format-version: 1.2 data-version: 2013-05-14 date: 14:05:2013 16:20 saved-by: midori auto-generated-by: OBO-Edit 2.3-beta5 subsetdef: abnormal_slim "Abnormal/normal slim" subsetdef: absent_slim "Absent/present slim" subsetdef: attribute_slim "Attribute slim" subsetdef: biosapiens "biosapiens protein feature ontology" subsetdef: cell_quality "cell_quality" subsetdef: Cross_product_review "Involved_in" subsetdef: cyclostome_subset "cyclostome structures" subsetdef: DBVAR "database of genomic structural variation" subsetdef: defined_by_ordinal_series "classes that are defined by relative position counting from first in a series of elements along an axis in an individual organism rather than by strict homology" subsetdef: developmental_classification "developmental_classification" subsetdef: disjointness_axiom_removed "A class which has a weakened disjointness axiom, to avoid inconsistency. These are kept separately in the uberon_disjoint_from_strict ontology." subsetdef: disposition_slim "Disposition slim" subsetdef: dubious_grouping "Indicates that subclasses in AOs may be inappropriately linked" subsetdef: early_development "A class that represents an early developmental structure, like a blastocyst. This part of the ontology is undergoing review to remove inappropriate grouping classes." subsetdef: emapa_ehdaa2 "derived from the union of EHDAA2 and EMAPA - still to be checked" subsetdef: functional_classification "functional_classification" subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation" subsetdef: gocheck_do_not_manually_annotate "Term not to be used for direct manual annotation" subsetdef: goslim_aspergillus "Aspergillus GO slim" subsetdef: goslim_candida "Candida GO slim" subsetdef: goslim_generic "Generic GO slim" subsetdef: goslim_goa "GOA and proteome slim" subsetdef: goslim_metagenomics "Metagenomics GO slim" subsetdef: goslim_pir "PIR GO slim" subsetdef: goslim_plant "Plant GO slim" subsetdef: goslim_pombe "Fission yeast GO slim" subsetdef: goslim_yeast "Yeast GO slim" subsetdef: gosubset_prok "Prokaryotic GO subset" subsetdef: grouping_class "Subset consisting of classes creating for grouping purposes" subsetdef: high_level_annotation_qc "High-level terms not to be used for direct annotation" subsetdef: inconsistent_with_fma "classes that have some inconsistency with FMA" subsetdef: inherited_grouping_class "A grouping class that originates in two or more separate anatomical ontologies. Includes 'region of X' type terms" subsetdef: loose_concept "loose concept" subsetdef: major_organ "somewhat fuzzy grouping for analysis purposes, currently composed of something like: liver, heart, skeletal, kidney, bladder, brain, skin, mouth, esophagus, stomach, small intestine, large intestines, trachea nose, lungs, brain, spinal cord, peripheral nerves, kidneys, ureters, bladder, urethra, gonads" subsetdef: metazoa_core "core classes typically found across metazoa. one purpose is to create a rough set of terms that could be used to start a new metazoan AO. Note this subset is not yet fully fleshed out" subsetdef: mf_needs_review "Catalytic activity terms in need of attention" subsetdef: mpath_slim "Pathology slim" subsetdef: non_informative "abstract class brought in to group ontology classes but not informative" subsetdef: organ_slim "organs, excluding individual muscles and skeletal elements" subsetdef: phenotype_rcn "A subset specifically created for the 2012 Phenotype RCN meeting. Includes some human-specific terms that may eventually be removed when they are adequately represented with part of relationships in FMA" subsetdef: qc_do_not_annotate "Term not to be used for direct annotation" subsetdef: qc_do_not_manually_annotate "Term not to be used for direct manual annotation" subsetdef: relational_slim "Relational slim: types of quality that require an additional entity in order to exist" subsetdef: scalar_slim "Scalar slim" subsetdef: SOFA "SO feature annotation" subsetdef: termgenie_unvetted "Terms created by TermGenie that do not follow a template and require additional vetting by editors" subsetdef: uberon_slim "Uberon slim - somewhat arbitrary subset that excludes obscure terms and deep compositional terms" subsetdef: ubprop:upper_level "abstract upper-level terms not directly useful for analysis" subsetdef: unverified_taxonomic_grouping "Indicates that the class encompasses classes from other AOs that have not been verified" subsetdef: unvetted "" subsetdef: upper_level "abstract upper-level terms not directly useful for analysis" subsetdef: upper_ontology_conflict "Terms in this subset group together terms from different anatomy ontologies that have conflicting upper ontology/CARO assignments. For example, in FMA the naris is immaterial and in ZFA it is an organism subdivision." subsetdef: value_slim "Value slim" subsetdef: vertebrate_core "core classes typically found across vertebrates. one purpose is to create a rough set of terms that could be used to start a new vertebrate AO" subsetdef: vessel_or_tree "A term classified differently in FMA due to its treatment of branching structures - to be reviewed and revised by editors" subsetdef: virus_checked "Viral overhaul terms" synonymtypedef: aa1 "amino acid 1 letter code" synonymtypedef: aa3 "amino acid 3 letter code" synonymtypedef: AAMOD "amino acid modification" synonymtypedef: ABBREVIATION "abbreviation" synonymtypedef: ATTRIBUTION_REQUIRED "expert consultation and attribution required" synonymtypedef: BRAND_NAME "BRAND NAME" synonymtypedef: BS "biosapiens" synonymtypedef: dbsnp "dbsnp variant terms" synonymtypedef: dbvar "DBVAR" synonymtypedef: DEPRECATED "A historic synonym, no longer encouraged" synonymtypedef: DEVELOPMENTAL "developmental term" synonymtypedef: DUBIOUS "dubious or contested synonym" synonymtypedef: ebi_variants "ensembl variant terms" synonymtypedef: FORMULA "FORMULA" synonymtypedef: GE "LANGUAGE GERMAN" synonymtypedef: HOMOLOGY "a synonym made on the basis of a possibly homologous structure in another species" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: InChI "InChI" synonymtypedef: InChIKey "InChIKey" synonymtypedef: INCONSISTENT "indicates that a synonym is used in an inconsistent or confusing way, typically between species" synonymtypedef: INN "INN" synonymtypedef: IUPAC_NAME "IUPAC NAME" synonymtypedef: LATIN "latin term" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "Unique short label for PRO terms for display purposes" EXACT synonymtypedef: PSI-MOD-label "Unique short label curated by PSI-MOD" EXACT synonymtypedef: RNAMOD "RNA modification" EXACT synonymtypedef: SCI "SCIENTIFIC NAME" synonymtypedef: SENSU "taxonomic disambiguation" synonymtypedef: SMILES "SMILES" synonymtypedef: systematic_synonym "Systematic synonym" EXACT default-namespace: fission_yeast_phenotype remark: svn version: $Revision: 654 $ ontology: fypo [Term] id: FYPO:0000001 name: phenotype def: "Any of the set of observable characteristics of an organism resulting from the interaction of its genotype with the environment." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast phenotype" EXACT [PomBase:mah] creation_date: 2011-03-16T03:59:25Z [Term] id: FYPO:0000002 name: cell phenotype def: "A phenotype that is observed at the level of an individual cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast cell phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-03-16T04:25:28Z [Term] id: FYPO:0000003 name: cell population phenotype def: "A phenotype that is observed at the level of a population of cells." [PomBase:mah] comment: note: differentium is population level, and may reflect observation conditions synonym: "fission yeast cell population phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-03-16T04:26:35Z [Term] id: FYPO:0000004 name: cell viability def: "A cell phenotype that consists of the cell's disposition to survive and develop normally." [PomBase:mah] comment: Viability is usually determined under standard laboratory conditions, i.e. a cell is generally considered viable if it can grow in rich medium under normal conditions such as temperature, pressure, oxygen level, pH, etc. is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000005 name: abnormal cell morphology alt_id: FYPO:0000019 def: "A cell phenotype characterized by altered cell morphology." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell morphology, misshapen cells" RELATED [PomBase:mah] synonym: "cellular morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000136 ! cellular structure phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000006 name: abnormal DNA damage checkpoint def: "A cell cycle checkpoint phenotype in which any DNA damage checkpoint is abnormal. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to activate under appropriate conditions, or may occur to a greater or lesser extent than wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal DNA damage checkpoint activation" EXACT [PomBase:mah] synonym: "abnormal DNA damage checkpoint during cellular response to DNA damage" EXACT [PomBase:al] synonym: "abnormal DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "DNA damage checkpoint defects" EXACT [PomBase:mah] is_a: FYPO:0000157 ! abnormal response to DNA damage stimulus is_a: FYPO:0000643 ! abnormal DNA integrity checkpoint created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000007 name: abnormal S-phase DNA damage checkpoint alt_id: FYPO:0000195 def: "A cell cycle checkpoint phenotype in which the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is abnormal. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to activate under appropriate conditions, or may occur to a greater or lesser extent than wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal intra-S DNA damage checkpoint" EXACT [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint activation" EXACT [PomBase:mah] synonym: "abnormal S-phase DNA damage checkpoint during vegetative growth" EXACT [PomBase:mah] synonym: "DNA damage checkpoint defects, S-phase" EXACT [PomBase:mah] is_a: FYPO:0000006 ! abnormal DNA damage checkpoint created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000008 name: abnormal meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination is abnormal. Meiotic recombination is a cellular process in which double strand breaks are formed and repaired through a double Holliday junction intermediate, resulting in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes." [GO:0007131, PomBase:mah] synonym: "abnormal meiotic DNA recombination" EXACT [PomBase:mah] synonym: "abnormal reciprocal meiotic recombination" EXACT [PomBase:mah] synonym: "DNA recombination defects, meiotic" EXACT [PomBase:mah] synonym: "meiotic recombination: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000063 ! abnormal DNA recombination created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000009 name: abnormal cell adhesion during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which adhesion of a cell to a substrate or another cell is abnormal." [PomBase:mah] synonym: "adhesion defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001872 ! abnormal cell adhesion created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000010 name: abolished cell-substrate adhesion def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells fail to adhere to a substrate." [PomBase:mah] synonym: "cell-substrate adhesion abolished" EXACT [PomBase:mah] synonym: "cell-substrate adhesion abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000011 name: abnormal cell cycle progression alt_id: FYPO:0000406 def: "A cellular process phenotype in which a cell does not proceed normally through a cell cycle." [PomBase:mah] synonym: "abnormal cell-division cycle" EXACT [GO:0007049, PomBase:mah] synonym: "cell cycle defects" EXACT [PomBase:mah] synonym: "cell cycle progression: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000631 ! cell cycle phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000012 name: mitotic G2/M transition delay alt_id: FYPO:0000205 alt_id: FYPO:0000401 alt_id: FYPO:0000604 alt_id: FYPO:0000605 alt_id: FYPO:0000606 alt_id: FYPO:0000971 def: "A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle takes place later than normal. The duration of G2 phase is thus longer than normal." [PomBase:mah] comment: A G2/M delay may indicate that a checkpoint, such as the DNA replication checkpoint or the G2/M DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "cell cycle progression through the G2/M phase transition: delayed" EXACT [SGD:phenotype_annotation] synonym: "cell cycle, mitotic G2 delay" RELATED [PomBase:mah] synonym: "decreased rate of mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "delayed cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "delayed mitotic G2 phase progression" RELATED [PomBase:mah] synonym: "DNA replication arrest" RELATED [PomBase:vw] synonym: "DNA replication checkpoint activated" RELATED [PomBase:mah] synonym: "G2/M transition DNA damage checkpoint activated" RELATED [PomBase:mah] synonym: "increased duration of mitotic G2 phase" EXACT [PomBase:mah] synonym: "increased duration of mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased mitotic G2 duration" EXACT [PomBase:mah] synonym: "mitotic cell cycle delay at G2/M transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G2 phase: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in G2 phase: delayed" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in G2 phase: increased duration" EXACT [SGD:phenotype_annotation] synonym: "mitotic G2 delay" RELATED [PomBase:mah] synonym: "mitotic G2/M transition delay during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of mitotic G2 phase progression" RELATED [PomBase:mah] is_a: FYPO:0000403 ! increased duration of cell cycle progression through mitotic G2/M phase transition is_a: FYPO:0000409 ! delayed cell cycle phase transition is_a: FYPO:0000563 ! abnormal mitotic G2 phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000013 name: T-shaped cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in the form of the letter T." [PomBase:mah, PomBase:vw] comment: A T-shaped cell may septate perpendicular to the normal septation axis, and divide to form normal-shaped daughter cells. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "cell morphology, T shaped" EXACT [PomBase:mah] synonym: "T-shaped cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000014 name: bottle-shaped cell def: "A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell morphology, bottle/skittle" EXACT [PomBase:mah] synonym: "skittle-shaped cell" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000015 name: branched cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a daughter cell grows from near, and at approximately a right angle to, the septum of the mother cell, resulting in the formation of a branched, septated cell. Cell division may give rise to branched or unbranched daughter cells." [PomBase:jh, PomBase:mah] synonym: "branched cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "cell morphology, branched" EXACT [PomBase:mah] is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000016 name: curved cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line." [PomBase:mah] synonym: "bent cell" EXACT [PomBase:mah] synonym: "cell morphology, curved" EXACT [PomBase:mah] synonym: "comma-shaped cell" EXACT [PomBase:vw] synonym: "curved cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000017 name: elongated cell def: "A cell morphology phenotype in which cells are longer than normal, i.e. the maximum distance between the cell ends is greater than normal." [PomBase:mah, PomBase:vw] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell morphology, elongated cell" EXACT [PomBase:mah] synonym: "long cell" EXACT [PomBase:vw] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000020 name: pear-shaped cell def: "A cell morphology phenotype in which a cell is shaped in the form of a pear." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell morphology, pear shaped" EXACT [PomBase:mah] is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000021 name: spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged." [PomBase:mah] synonym: "cell morphology, round vegetative cell" RELATED [PomBase:mah] synonym: "cell morphology, rounded vegetative cell" RELATED [PomBase:mah] synonym: "spheroid cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001955 ! spheroid cell created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000022 name: shmoo with long tip def: "A cell morphology phenotype in which a cell forms a mating projection with a longer tip than normal." [PomBase:mah] synonym: "cell morphology, shmoos with long tips" EXACT [PomBase:mah] synonym: "conjugation tube with long tip" EXACT [PomBase:mah] synonym: "mating projection with long tip" EXACT [PomBase:mah] is_a: FYPO:0000357 ! abnormal shmoo morphology created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000023 name: small cell def: "A cell morphology phenotype in which a cell has an abnormally low volume." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell size: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001127 ! abnormal cell size created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000024 name: stubby cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which the cell diameter is larger than normal and the cell length is shorter than normal." [PomBase:mah] synonym: "cell morphology, stubby cells" EXACT [PomBase:mah] synonym: "stubby cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000025 name: swollen cell def: "A cell morphology phenotype in which a cell has a larger volume than normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cell morphology, swollen cells" EXACT [PomBase:mah] is_a: FYPO:0001127 ! abnormal cell size created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000026 name: abnormal cell polarity def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is abnormal." [PomBase:mah] synonym: "abnormal cell polarity during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal establishment or maintenance of cell polarity" EXACT [PomBase:mah] synonym: "cell polarity defects" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000027 name: abnormal cell wall def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the cell wall is abnormal." [PomBase:mah] synonym: "abnormal cell wall during vegetative growth" EXACT [PomBase:mah] synonym: "cell wall defects" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000029 name: abnormal chromosome segregation alt_id: FYPO:0000226 def: "A cellular process phenotype in which chromosome segregation is abnormal. Chromosome segregation begins with the alignment of chromosomes at the metaphase plate, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GO:0007059, PomBase:mah] synonym: "centromere function defective" RELATED [PomBase:mah] synonym: "chromosome segregation defects" EXACT [PomBase:mah] synonym: "chromosome segregation: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000030 name: abnormal mitotic chromosome congression def: "A cellular process phenotype in which chromosome congression is abnormal during mitosis. Chromosome congression is the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle." [GO:0051310, PomBase:mah] synonym: "abnormal chromosome congression at mitotic metaphase plate" EXACT [PomBase:mah] synonym: "abnormal chromosome congression during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic metaphase plate congression" EXACT [GO:0007080] synonym: "chromosome segregation defects, chromosome congression" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth relationship: part_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000031 name: abnormal conjugation def: "A cellular process phenotype in which conjugation is abnormal. Conjugation, also known as mating, is a process that results in the union of cellular and genetic information from cells of compatible mating types." [GO:0000747, PomBase:mah] synonym: "abnormal conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "abnormal zygote formation" RELATED [PomBase:mah] synonym: "conjugation defects" EXACT [PomBase:mah] is_a: FYPO:0000301 ! mating phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000032 name: abnormal cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis is abnormal. Cytokinesis is part of the cell cycle and results in the division of the cytoplasm of a cell and its separation into two daughter cells." [GO:0033205, PomBase:mah] synonym: "abnormal cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "abnormal cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "cytokinesis defects" EXACT [PomBase:mah] synonym: "cytokinesis: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000033 name: abnormal contractile ring localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring localization is abnormal. Contractile ring localization is the part of cytokinesis in which contractile ring is assembled and/or maintained in a specific location." [GO:0032187, PomBase:mah] comment: Note that the location of the contractile ring is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. synonym: "abnormal contractile ring localisation" EXACT [PomBase:mah] synonym: "abnormal contractile ring localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring localization involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "cytokinesis defects, misplaced contractile ring" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000034 name: abnormal endocytosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [GO:0006897, PomBase:mah] synonym: "abnormal actin-mediated endocytosis" EXACT [PomBase:vw] synonym: "abnormal endocytosis during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis defects" EXACT [PomBase:mah] synonym: "endocytosis: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000035 name: growth auxotrophic for arginine def: "Auxotrophy in which arginine is required for vegetative cell growth." [PomBase:mah] synonym: "arginine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for arginine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000036 name: growth auxotrophic for asparagine def: "Auxotrophy in which asparagine is required for vegetative cell growth." [PomBase:mah] synonym: "asparagine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for asparagine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000037 name: growth auxotrophic for cysteine def: "Auxotrophy in which cysteine is required for vegetative cell growth." [PomBase:mah] synonym: "cysteine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for cysteine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000038 name: growth auxotrophic for ethanolamine def: "Auxotrophy in which ethanolamine is required for vegetative cell growth." [PomBase:mah] synonym: "ethanolamine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for ethanolamine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000039 name: growth auxotrophic for lysine def: "Auxotrophy in which lysine is required for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for lysine during vegetative growth" EXACT [PomBase:mah] synonym: "lysine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000040 name: growth auxotrophic for methionine def: "Auxotrophy in which methionine is required for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for methionine during vegetative growth" EXACT [PomBase:mah] synonym: "methionine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000041 name: growth auxotrophic for phenylalanine def: "Auxotrophy in which phenylalanine is required for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for phenylalanine during vegetative growth" EXACT [PomBase:mah] synonym: "phenylalanine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000042 name: growth auxotrophic for sulfite def: "Auxotrophy in which sulfite is required for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for sulfite during vegetative growth" EXACT [PomBase:mah] synonym: "sulfite auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000043 name: abnormal glucan synthesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which glucan biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal glucan biosynthetic process" EXACT [PomBase:mah] synonym: "abnormal glucan synthesis during vegetative growth" EXACT [PomBase:mah] synonym: "glucan synthesis defective" EXACT [PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000044 name: abnormal negative regulation of transcription by glucose alt_id: FYPO:0000210 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) is abnormal. Specific genes that are normally not transcribed in the presence of glucose are transcribed in the mutant." [GO:0045014, PomBase:mah] synonym: "abnormal glucose repression" EXACT [GO:0045014, PomBase:mah] synonym: "abnormal glucose repression during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal negative regulation of transcription by glucose during vegetative growth" EXACT [PomBase:mah] synonym: "glucose repression defects" EXACT [PomBase:mah] is_a: FYPO:0000624 ! abnormal negative regulation of transcription is_a: FYPO:0001484 ! abnormal cellular response to nutrient created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000045 name: abnormal cell population growth def: "A cell population phenotype in which a population of cells grow abnormally." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "growth defect" RELATED [PomBase:mah] is_a: FYPO:0000139 ! cell population growth phenotype is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000046 name: decreased cell population growth alt_id: FYPO:0000222 def: "A cell population phenotype in which cell population growth is decreased relative to normal. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "aerobic growth defects" RELATED [PomBase:mah] synonym: "decreased aerobic cell population growth" NARROW [PomBase:mah] synonym: "decreased growth" BROAD [PomBase:mah] synonym: "reduced aerobic cell population growth" NARROW [PomBase:mah] synonym: "reduced cell population growth" EXACT [PomBase:mah] synonym: "slow aerobic cell population growth" NARROW [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell population growth is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000047 name: normal cell population growth def: "A cell population phenotype in which a population of cells grow normally." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "growth normal" BROAD [PomBase:mah] is_a: FYPO:0000139 ! cell population growth phenotype is_a: FYPO:0002058 ! viable cell population relationship: has_part FYPO:0001419 ! normal cell population growth rate created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000048 name: invasive growth abolished alt_id: FYPO:0000465 def: "A cellular process phenotype in which invasive growth does not occur." [PomBase:mah] comment: This term was made obsolete because it is not required to describe fission yeast. synonym: "absent invasive growth" EXACT [PomBase:mah] synonym: "invasive growth abolished during vegetative growth" EXACT [PomBase:mah] synonym: "invasive growth: absent" EXACT [SGD:phenotype_annotation] is_obsolete: true consider: FYPO:0000551 created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000049 name: inviable cell def: "A viability phenotype in which a cell is unable to survive under conditions in which wild type cells survive." [PomBase:mah] comment: Viability is usually determined under standard laboratory conditions, i.e. a cell is generally considered inviable if it cannot grow in rich medium under normal conditions such as temperature, pressure, oxygen level, pH, etc. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "essential" RELATED [PomBase:mah] synonym: "lethal" EXACT [PomBase:mah] is_a: FYPO:0000004 ! cell viability created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000050 name: abnormal kinetochore structure def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the structure of the kinetochore is abnormal." [PomBase:mah] comment: Note that an abnormal kinetochore organization process may, but does not necessarily, result in abnormal kinetochore structure. synonym: "abnormal kinetochore structure during vegetative growth" EXACT [PomBase:mah] synonym: "kinetochore defects" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000807 ! abnormal kinetochore organization created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000051 name: abnormal meiosis alt_id: FYPO:0000738 def: "A cellular process phenotype in which meiosis is abnormal. Meiosis refers specifically to the nuclear division phase of a meiotic cell cycle." [PomBase:mah] synonym: "meiosis defects" EXACT [PomBase:mah] synonym: "meiosis: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000052 ! abnormal meiotic cell cycle progression created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000052 name: abnormal meiotic cell cycle progression def: "A cellular process phenotype in which a cell does not proceed normally through a meiotic cell cycle." [PomBase:mah] synonym: "meiotic cell cycle defects" EXACT [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000054 name: abnormal microtubule cytoskeleton organization alt_id: FYPO:0000053 def: "A phenotype that affects the organization of the microtubule cytoskeleton. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in abnormal microtubule cytoskeleton morphology. subset: qc_do_not_manually_annotate synonym: "abnormal microtubule cytoskeleton organisation" EXACT [PomBase:mah] synonym: "abnormal microtubule organisation" RELATED [PomBase:mah] synonym: "abnormal microtubule organization" RELATED [PomBase:mah] synonym: "microtubule cytoskeleton defects" EXACT [PomBase:mah] synonym: "microtubule organization defects" RELATED [PomBase:mah] is_a: FYPO:0000297 ! microtubule cytoskeleton organization phenotype is_a: FYPO:0000802 ! abnormal cytoskeleton organization created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000055 name: long microtubules def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are longer than normal." [PomBase:mah] synonym: "elongated microtubules" EXACT [PomBase:mah] synonym: "long microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule organization defects, long microtubules" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000056 name: mitochondria fused def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which mitochondria have fused into fewer and larger structures than normal." [PomBase:mah] synonym: "mitochondria fused during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000359 ! abnormal mitochondrial morphology created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000057 name: mitochondrial nucleoid enlarged def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the mitochondrial nucleoid is larger than normal." [PomBase:mah] synonym: "mitochondrial nucleoid enlarged during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000058 name: mitochondrial nucleoid decreased number def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer mitochondrial nucleoids than normal." [PomBase:mah] synonym: "mitochondrial nucleoid decreased number during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial nucleoid reduced number" EXACT [PomBase:mah] synonym: "mitochondrial nucleoids present in decreased number" RELATED [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000059 name: abnormal mitotic cell cycle progression def: "A cellular process phenotype in which a cell does not proceed normally through a mitotic cell cycle." [PomBase:mah] synonym: "mitotic cell cycle defects" EXACT [PomBase:mah] synonym: "mitotic cell cycle: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000011 ! abnormal cell cycle progression created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000060 name: mononucleate def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single nucleus." [PomBase:mah] synonym: "mononucleate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000061 name: multinucleate def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "multinucleate cells" EXACT [PomBase:al] synonym: "multinucleate during vegetative growth" EXACT [PomBase:mah] synonym: "multiple nuclei" EXACT [PomBase:al] is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000062 name: abnormal nuclear morphology alt_id: FYPO:0000259 def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the nucleus is abnormal." [PomBase:mah] comment: Note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "abnormal nuclear morphology during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear morphology defects" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000810 ! abnormal nucleus organization created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000063 name: abnormal DNA recombination def: "A cellular process phenotype in which DNA recombination is abnormal. DNA recombination is a process that results in reassortment of genes, producing gene combinations different from those that were present in the parents." [GO:0006310, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "recombination defects" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000064 name: resistance to 2-deoxyglucose def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 2-deoxyglucose than normal." [PomBase:mah] synonym: "resistance to 2-deoxyglucose during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to 2-DOG" EXACT [PomBase:mah] synonym: "resistant to 2-deoxy-D-glucose" EXACT [CHEBI:15866, PomBase:mah] synonym: "resistant to 2-DOG" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000065 name: resistance to 5-azacytidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-azacytidine than normal." [PomBase:mah] synonym: "resistance to 5-azacytidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to 5-azacytidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000066 name: resistance to L-azetidine-2-carboxylic acid def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-azetidine-2-carboxylic acid than normal." [PomBase:mah] synonym: "resistance to (S)-azetidine-2-carboxylic acid" EXACT [CHEBI:6198, PomBase:mah] synonym: "resistance to AZC" BROAD [PomBase:mah] synonym: "resistance to L-azetidine-2-carboxylic acid during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to L-azetidine-2-carboxylic acid" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000067 name: resistance to brefeldin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of brefeldin A than normal." [PomBase:mah] synonym: "resistance to BFA" EXACT [PomBase:mah] synonym: "resistance to brefeldin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to Brefeldin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000068 name: resistance to K-252a def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of K-252a than normal." [PomBase:mah] synonym: "resistance to K-252a during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to K-252a" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000069 name: resistance to thiabendazole def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of thiabendazole than normal." [PomBase:mah] synonym: "resistance to TBZ" EXACT [PomBase:mah] synonym: "resistance to thiabendazole during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to TBZ" EXACT [CHEBI:45979, PomBase:mah] synonym: "resistant to thiabendazole" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical [Term] id: FYPO:0000070 name: resistance to amphotericin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amphotericin B than normal." [PomBase:mah] synonym: "resistance to amphotericin B during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to amphotericin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000071 name: resistance to aureobasidin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aureobasidin A than normal." [PomBase:mah] synonym: "resistance to AbA" EXACT [PMID:9472078] synonym: "resistance to aureobasidin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to aureobasidin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000072 name: resistance to benomyl def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of benomyl than normal." [PomBase:mah] synonym: "resistance to benomyl during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to MBC" EXACT [PMID:6887244] synonym: "resistance to methyl benzimidazole-2-yl-carbamate" EXACT [PMID:6887244] synonym: "resistant to benomyl" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000073 name: resistance to caffeine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caffeine than normal." [PomBase:mah] synonym: "resistance to caffeine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to caffeine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000074 name: resistance to drug def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of a drug than normal." [PomBase:mah] synonym: "drug resistance" EXACT [PomBase:mah] synonym: "drug resistant" EXACT [PomBase:mah] synonym: "resistance to drug during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to drugs" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000075 name: resistance to lovastatin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lovastatin than normal." [PomBase:mah] synonym: "resistance to lovastatin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to lovastatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000076 name: resistance to nystatin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nystatin than normal." [PomBase:mah] synonym: "resistance to nystatin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to nystatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000077 name: resistance to rapamycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of rapamycin than normal." [PomBase:mah] synonym: "resistance to rapamycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to rapamycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000078 name: abnormal cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration is abnormal." [PomBase:mah] synonym: "abnormal cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal respiration" BROAD [PomBase:mah] synonym: "abnormal respiratory metabolism" EXACT [PomBase:mah] synonym: "respiratory metabolism: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000079 name: sensitive to caspofungin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caspofungin. Cells stop growing (and may die) at a concentration of caspofungin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to caspofungin" EXACT [PomBase:mah] synonym: "sensitive to caspofungin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to glucan synthase inhibitor" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000080 name: sensitive to cold def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cold; cells fail to grow or grow more slowly than normal at low temperatures." [PomBase:mah] synonym: "cold sensitive" EXACT [PomBase:mah] synonym: "cold sensitivity: increased" EXACT [SGD:phenotype_annotation] synonym: "hypersensitive to cold" EXACT [PomBase:mah] synonym: "sensitive to cold during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000081 name: sensitive to high osmolarity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to conditions of high osmolarity." [PomBase:mah] synonym: "hyperosmotic stress resistance: decreased" EXACT [SGD:phenotype_annotation] synonym: "hypersensitive to high osmolarity" EXACT [PomBase:mah] synonym: "sensitive to high osmolarity during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to hyperosmotic conditions" EXACT [PomBase:mah] is_a: FYPO:0000270 ! sensitive to osmotic stress created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000082 name: sensitive to high temperature def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to heat. For example, cells may fail to grow or grow more slowly than normal at high temperatures." [PomBase:mah] comment: For fission yeast, high temperature usually corresponds to above 32 degrees Celsius. synonym: "heat sensitive" EXACT [PomBase:mah] synonym: "heat sensitivity: increased" EXACT [SGD:phenotype_annotation] synonym: "hypersensitive to high temperature" EXACT [PomBase:mah] synonym: "sensitive to heat" EXACT [PomBase:mah] synonym: "sensitive to high temperature during vegetative growth" EXACT [PomBase:mah] synonym: "temperature sensitive" RELATED [PomBase:mah] is_a: FYPO:0000212 ! abnormal cellular response to heat is_a: FYPO:0000304 ! sensitive to stress created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000083 name: sensitive to enfumafungin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to enfumafungin. Cells stop growing (and may die) at a concentration of enfumafungin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to enfumafungin" EXACT [PomBase:mah] synonym: "sensitive to enfumafungin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to glucan synthase inhibitor" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000084 name: sensitive to 6-azauracil def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 6-azauracil. Cells stop growing (and may die) at a concentration of 6-azauracil that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 6-azauracil" EXACT [PomBase:mah] synonym: "sensitive to 6-azauracil during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000085 name: sensitive to camptothecin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to camptothecin. Cells stop growing (and may die) at a concentration of camptothecin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to camptothecin" EXACT [PomBase:mah] synonym: "sensitive to camptothecin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to CPT" EXACT [CHEBI:27656, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000086 name: sensitive to tacrolimus def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tacrolimus. Cells stop growing (and may die) at a concentration of tacrolimus that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tacrolimus" EXACT [PomBase:mah] synonym: "sensitive to FK506" EXACT [CHEBI:61057, PomBase:mah] synonym: "sensitive to tacrolimus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000087 name: sensitive to hydrogen peroxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrogen peroxide. Cells stop growing (and may die) at a concentration of hydrogen peroxide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hydrogen peroxide" EXACT [PomBase:mah] synonym: "sensitive to H2O2" EXACT [PomBase:mah] synonym: "sensitive to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000088 name: sensitive to hydroxyurea def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydroxyurea. Cells stop growing (and may die) at a concentration of hydroxyurea that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hydroxyurea" EXACT [PomBase:mah] synonym: "sensitive to HU" EXACT [PomBase:mah] synonym: "sensitive to hydroxyurea during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000089 name: sensitive to methyl methanesulfonate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methyl methanesulfonate. Cells stop growing (and may die) at a concentration of methyl methanesulfonate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to methyl methanesulfonate" EXACT [PomBase:mah] synonym: "sensitive to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to MMS" EXACT [CHEBI:25255, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000090 name: sensitive to N-ethylmaleimide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N-ethylmaleimide. Cells stop growing (and may die) at a concentration of N-ethylmaleimide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to N-ethylmaleimide" EXACT [PomBase:mah] synonym: "sensitive to N-ethylmaleimide during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to NEM" EXACT [CHEBI:44485, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000091 name: sensitive to thiabendazole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to thiabendazole. Cells stop growing (and may die) at a concentration of thiabendazole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to thiabendazole" EXACT [PomBase:mah] synonym: "sensitive to TBZ" EXACT [CHEBI:45979, PomBase:mah] synonym: "sensitive to thiabendazole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000092 name: sensitive to amiodarone def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amiodarone. Cells stop growing (and may die) at a concentration of amiodarone that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to amiodarone" EXACT [PomBase:mah] synonym: "sensitive to amiodarone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000093 name: sensitive to arsenic def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to arsenic. Cells stop growing (and may die) at a concentration of arsenic that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to arsenic" EXACT [PomBase:mah] synonym: "sensitive to arsenic during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000094 name: sensitive to benomyl def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to benomyl. Cells stop growing (and may die) at a concentration of benomyl that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to benomyl" EXACT [PomBase:mah] synonym: "sensitive to benomyl during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000095 name: sensitive to bleomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bleomycin. Cells stop growing (and may die) at a concentration of bleomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bleomycin" EXACT [PomBase:mah] synonym: "sensitive to bleomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000096 name: sensitive to cadmium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cadmium. Cells stop growing (and may die) at a concentration of cadmium that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cadmium" EXACT [PomBase:mah] synonym: "sensitive to cadmium during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000097 name: sensitive to caffeine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caffeine. Cells stop growing (and may die) at a concentration of caffeine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to caffeine" EXACT [PomBase:mah] synonym: "sensitive to caffeine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000098 name: sensitive to calcium def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium. Cells stop growing (and may die) at a concentration of calcium ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to calcium" EXACT [PomBase:mah] synonym: "sensitive to calcium during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to calcium ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000099 name: sensitive to canavanine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to canavanine. Cells stop growing (and may die) at a concentration of canavanine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to canavanine" EXACT [PomBase:mah] synonym: "sensitive to canavanine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000100 name: sensitive to chloramphenicol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chloramphenicol. Cells stop growing (and may die) at a concentration of chloramphenicol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to chloramphenicol" EXACT [PomBase:mah] synonym: "sensitive to chloramphenicol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000101 name: sensitive to chlorpropham def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chlorpropham. Cells stop growing (and may die) at a concentration of chlorpropham that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to chlorpropham" EXACT [PomBase:mah] synonym: "sensitive to chlorpropham during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to isopropyl N-3-chlorophenyl carbamate" EXACT [PomBase:mah] synonym: "sensitive to spindle poison" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000102 name: sensitive to cisplatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cisplatin. Cells stop growing (and may die) at a concentration of cisplatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cisplatin" EXACT [PomBase:mah] synonym: "sensitive to cis-DDP" EXACT [CHEBI:27899] synonym: "sensitive to cisplatin during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to DDP" BROAD [CHEBI:27899, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000103 name: sensitive to copper def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to copper ions. Cells stop growing (and may die) at a concentration of copper ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to copper" EXACT [PomBase:mah] synonym: "sensitive to copper during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to copper ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:53:56Z [Term] id: FYPO:0000104 name: sensitive to cycloheximide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cycloheximide. Cells stop growing (and may die) at a concentration of cycloheximide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cycloheximide" EXACT [PomBase:mah] synonym: "sensitive to cycloheximide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000105 name: sensitive to cyclosporin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cyclosporin A. Cells stop growing (and may die) at a concentration of cyclosporin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cyclosporin A" EXACT [PomBase:mah] synonym: "sensitive to cyclosporin A during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to cyclosporine" EXACT [CHEBI:4031, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000106 name: sensitive to hygromycin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hygromycin B. Cells stop growing (and may die) at a concentration of hygromycin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to hygromycin B" EXACT [PomBase:mah] synonym: "sensitive to hygromycin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000107 name: sensitive to latrunculin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to latrunculin A. Cells stop growing (and may die) at a concentration of latrunculin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to latrunculin A" EXACT [PomBase:mah] synonym: "sensitive to latrunculin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000108 name: sensitive to menadione def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to menadione. Cells stop growing (and may die) at a concentration of menadione that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to menadione" EXACT [PomBase:mah] synonym: "sensitive to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to vitamin K3" RELATED [PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000109 name: sensitive to papulacandin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to papulacandin B. Cells stop growing (and may die) at a concentration of papulacandin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to papulacandin B" EXACT [PomBase:mah] synonym: "sensitive to papulacandin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000110 name: sensitive to pravastatin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to pravastatin. Cells stop growing (and may die) at a concentration of pravastatin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to pravastatin" EXACT [PomBase:mah] synonym: "sensitive to pravastatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000111 name: sensitive to rapamycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to rapamycin. Cells stop growing (and may die) at a concentration of rapamycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to rapamycin" EXACT [PomBase:mah] synonym: "sensitive to rapamycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000112 name: sensitive to sorbitol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sorbitol. Cells stop growing (and may die) at a concentration of sorbitol that allows wild type cells to grow." [PomBase:mah] comment: Also consider annotating to 'sensitive to osmotic stress' (FYPO:0000270). synonym: "hypersensitive to sorbitol" EXACT [PomBase:mah] synonym: "sensitive to glucitol" EXACT [CHEBI:30911, PomBase:mah] synonym: "sensitive to sorbitol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000113 name: sensitive to staurosporine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to staurosporine. Cells stop growing (and may die) at a concentration of staurosporine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to staurosporine" EXACT [PomBase:mah] synonym: "sensitive to staurosporine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000114 name: cellular process phenotype def: "A phenotype that affects a cellular process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "fission yeast cellular process phenotype" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2011-04-12T12:00:38Z [Term] id: FYPO:0000115 name: sensitive to valproic acid def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to valproic acid. Cells stop growing (and may die) at a concentration of valproic acid that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to valproic acid" EXACT [PomBase:mah] synonym: "sensitive to valproic acid during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000116 name: sensitive to zinc def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zinc ions. Cells stop growing (and may die) at a concentration of zinc ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to zinc" EXACT [PomBase:mah] synonym: "sensitive to zinc during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to zinc ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000117 name: abnormal septation alt_id: FYPO:0000170 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation is abnormal." [PomBase:mah] synonym: "abnormal barrier septum formation involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "abnormal septation during vegetative growth" EXACT [PomBase:mah] synonym: "septation defects" EXACT [PomBase:mah] synonym: "septum formation: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000118 name: multiseptate def: "A septation phenotype characterized by the presence of more than one septum in a cell." [PomBase:mah] synonym: "multiseptate cells" EXACT [PomBase:al] synonym: "multiseptate during vegetative growth" EXACT [PomBase:mah] synonym: "septation defects, multiple septa" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000117 ! abnormal septation created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000119 name: abnormal spindle assembly alt_id: FYPO:0000285 def: "A cellular process phenotype in which spindle assembly is abnormal. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle." [GO:0051225, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization is_a: FYPO:0000336 ! abnormal cellular component assembly created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000120 name: abnormal spindle alt_id: FYPO:0000367 def: "A cellular structure phenotype in which the structure of the mitotic or meiotic spindle is abnormal." [PomBase:mah] synonym: "abnormal spindle morphology" EXACT [PomBase:mah] synonym: "spindle defects" EXACT [PomBase:mah] synonym: "spindle morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000287 ! abnormal subcellular structure created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000121 name: abnormal sporulation def: "A cellular process phenotype in which ascospore formation is abnormal." [PomBase:mah] synonym: "abnormal ascospore formation" EXACT [PomBase:mah] synonym: "sporulation defects" EXACT [PomBase:mah] synonym: "sporulation: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000122 name: abnormal telomere maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is abnormal." [GO:0000723, PomBase:mah] synonym: "abnormal telomere maintenance during vegetative growth" EXACT [PomBase:mah] synonym: "telomere maintenance defects" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000123 name: large vacuoles def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are larger than normal." [PomBase:mah] synonym: "large vacuoles during vegetative growth" EXACT [PomBase:mah] synonym: "vacuole organization defects, large vacuoles" EXACT [PomBase:mah] is_a: FYPO:0000368 ! abnormal vacuolar morphology created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000124 name: viable cell def: "A viability phenotype in which a cell is able to survive under the specified conditions." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000004 ! cell viability created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000125 name: resistance to amiloride def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amiloride than normal." [PomBase:mah] synonym: "resistance to amiloride during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to amiloride" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000126 name: increased resistance to chemical def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased resistance to a chemical stimulus. Resistance to a chemical is usually measured by determining the maximum concentration of the chemical at which a population of cells grow and divide." [PomBase:mah] synonym: "increased resistance to chemical during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to chemicals: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001358 ! vegetative cell population growth phenotype created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000127 name: increased sensitivity to chemical def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased resistance to a chemical stimulus. Resistance to a chemical is measured by determining the maximum concentration of the chemical at which a population of cells grow and divide. Typically, cells are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type cells to grow." [PomBase:mah] synonym: "increased sensitivity to chemical during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to chemicals: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001358 ! vegetative cell population growth phenotype created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000128 name: auxotrophy def: "A phenotype characterized by a cell's inability to synthesize a particular organic compound required for its growth." [PATO:0000422, PomBase:mah] synonym: "auxotrophy during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth is_a: FYPO:0001358 ! vegetative cell population growth phenotype created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000129 name: spherical vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is formed in the shape of a sphere." [PomBase:mah] synonym: "orb during vegetative growth" EXACT [PomBase:jh, PomBase:vw] synonym: "spherical cells during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0001956 ! spherical cell created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000130 name: short spindle def: "A spindle phenotype in which the spindle is shorter than normal." [PomBase:mah] synonym: "short spindles" EXACT [PomBase:mah] synonym: "spindle defects, short spindles" EXACT [PomBase:mah] is_a: FYPO:0000120 ! abnormal spindle created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000131 name: abnormal mitotic spindle elongation def: "A spindle phenotype in which mitotic spindle elongation, i.e. the process of lengthening the distance between poles of the mitotic spindle, is abnormal." [GO:0000022, PomBase:mah] synonym: "abnormal mitotic spindle elongation during vegetative growth" EXACT [PomBase:mah] synonym: "spindle elongation defects" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth relationship: part_of FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000132 name: abnormal septum disassembly def: "A cellular process phenotype characterized by abnormal primary cell septum disassembly; may result in the formation of chains of attached cells." [PomBase:mah] synonym: "abnormal septum disassembly during vegetative growth" EXACT [PomBase:mah] synonym: "chained cells" RELATED [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000133 name: elongated multinucleate cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus and is elongated." [PomBase:mah] synonym: "elongated multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "long multinucleate cell" EXACT [PomBase:vw] is_a: FYPO:0000061 ! multinucleate is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000061 ! multinucleate relationship: output_of FYPO:0000032 ! abnormal cytokinesis created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000134 name: branched, elongated, multiseptate cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell forms one or more branches near a septum, is elongated, and has more than one septum." [PomBase:mah] synonym: "branched, elongated, multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, long, multiseptate cell" EXACT [PomBase:vw] is_a: FYPO:0000223 ! elongated multiseptate cells is_a: FYPO:0001512 ! branched, elongated cell relationship: has_part FYPO:0000015 ! branched cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000118 ! multiseptate created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000135 name: abnormal plasma membrane sterol distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the plasma membrane is abnormal." [PomBase:mah] synonym: "abnormal plasma membrane sterol distribution during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of plasma membrane sterol distribution" EXACT [PomBase:mah] synonym: "localization defects, sterol distribution defects" EXACT [PomBase:mah] is_a: FYPO:0000813 ! abnormal plasma membrane organization is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-03-29T05:54:40Z [Term] id: FYPO:0000136 name: cellular structure phenotype def: "A phenotype that affects the structure of a cell or a cellular component." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast cellular structure phenotype" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2011-04-12T12:01:21Z [Term] id: FYPO:0000137 name: cell cycle checkpoint phenotype def: "A cell phenotype that affects any cell cycle checkpoint." [PomBase:mah] synonym: "fission yeast cell cycle checkpoint phenotype" EXACT [PomBase:mah] is_a: FYPO:0000631 ! cell cycle phenotype is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2011-04-12T12:55:38Z [Term] id: FYPO:0000138 name: localization phenotype def: "A cell phenotype that affects the localization of a structure or substance in a cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast localization phenotype" EXACT [PomBase:mah] synonym: "localisation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T02:16:04Z [Term] id: FYPO:0000139 name: cell population growth phenotype def: "A cell phenotype that affects the rate or extent of cell population growth." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast cell population growth phenotype" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2011-04-12T02:22:51Z [Term] id: FYPO:0000140 name: cellular metabolism phenotype def: "A cellular process phenotype that affects metabolism in the cell." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast cellular metabolism phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T02:23:26Z [Term] id: FYPO:0000141 name: abnormal mitotic sister chromatid segregation alt_id: FYPO:0001359 def: "A cellular process phenotype in which mitotic sister chromatid segregation is abnormal. Mitotic sister chromatid segregation is the entire process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle." [GO:0000070, PomBase:mah] synonym: "abnormal chromosome segregation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid segregation during vegetative growth" EXACT [PomBase:mah] synonym: "centromere function defective during vegetative growth" RELATED [PomBase:mah] synonym: "chromosome segregation defects during vegetative growth" EXACT [PomBase:mah] synonym: "chromosome segregation defects, mitotic" EXACT [PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation is_a: FYPO:0000641 ! abnormal chromosome organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth relationship: part_of FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2011-04-12T05:41:15Z [Term] id: FYPO:0000142 name: gene expression phenotype def: "A cellular process phenotype that affects gene expression. Gene expression includes transcription, RNA processing, and, for protein-coding genes, translation and protein maturation." [GO:0010467, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast gene expression phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T05:46:51Z [Term] id: FYPO:0000143 name: transcription regulation phenotype def: "A gene expression phenotype that affects the regulation of DNA-dependent transcription." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast transcription regulation phenotype" EXACT [PomBase:mah] synonym: "gene-specific transcription regulation phenotype" RELATED [GO:0006355, PomBase:mah] synonym: "transcriptional control phenotype" BROAD [GO:0006355, PomBase:mah] is_a: FYPO:0000288 ! gene expression regulation phenotype created_by: midori creation_date: 2011-04-12T05:47:38Z [Term] id: FYPO:0000144 name: abnormal chromatin silencing def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal. Chromatin silencing is repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into heterochromatin." [GO:0006342, PomBase:mah] synonym: "abnormal chromatin silencing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000574 ! abnormal gene silencing is_a: FYPO:0000624 ! abnormal negative regulation of transcription created_by: midori creation_date: 2011-04-12T05:48:37Z [Term] id: FYPO:0000145 name: regulation phenotype def: "A cellular process phenotype that affects the regulation of a molecular function, biological process, or biological quality." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast regulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-12T06:00:44Z [Term] id: FYPO:0000146 name: abnormal chromatin silencing at centromere def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromeric regions is abnormal." [PomBase:mah] synonym: "abnormal chromatin silencing at centromere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000147 name: abnormal activation of bipolar cell growth def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which activation of bipolar cell growth is abnormal; results in abnormal new end take-off." [PomBase:mah] synonym: "abnormal activation of bipolar vegetative cell growth" EXACT [PomBase:mah] synonym: "abnormal NETO" EXACT [PomBase:mah] synonym: "abnormal new end take off" EXACT [PomBase:mah] is_a: FYPO:0000191 ! abnormal regulation of establishment or maintenance of cell polarity is_a: FYPO:0001392 ! abnormal regulation of cell growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000148 name: abnormal regulation of mitotic cell cycle def: "A regulation phenotype in which regulation of the mitotic cell cycle is abnormal." [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000149 name: transport phenotype def: "A cell process phenotype that affects a transport process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast transport phenotype" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype created_by: midori creation_date: 2011-04-14T05:43:20Z [Term] id: FYPO:0000150 name: abnormal colony morphology def: "A cell population phenotype in which the morphology of a colony growing on a solid surface is abnormal." [PomBase:mah] synonym: "colony shape: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000151 name: abnormal meiotic chromosome segregation def: "A cellular process phenotype in which meiotic chromosome segregation is abnormal. Meiotic chromosome segregation is the entire process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GO:0045132, PomBase:mah] is_a: FYPO:0000029 ! abnormal chromosome segregation is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000152 name: abnormal cellular response to nitrogen starvation def: "A stress response phenotype in which the response to nitrogen starvation is abnormal." [PomBase:mah] is_a: FYPO:0000713 ! abnormal cellular response to starvation created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000153 name: clumped cells def: "A colony morphology phenotype in which cells form clumps due to incomplete hydrolysis of septum edging material; cells remain attached via remnants of the septum edging." [PMID:15194814, PomBase:mah] is_a: FYPO:0000150 ! abnormal colony morphology created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000154 name: abnormal negative regulation of G0 to G1 transition def: "A regulation phenotype in which negative regulation of the G0 to G1 transition is abnormal." [PomBase:mah] synonym: "abnormal maintenance of cell cycle quiescence" EXACT [PomBase:mah] synonym: "abnormal maintenance of cell quiescence" EXACT [PomBase:mah] synonym: "abnormal maintenance of G0 arrest" EXACT [PomBase:mah] synonym: "abnormal maintenance of G0 phase" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000155 name: flocculating cells alt_id: FYPO:0000462 def: "A cell population phenotype that reflects increased occurrence of flocculation. Flocculation is the non-sexual aggregation of single cells." [GO:0000128, PomBase:mah] synonym: "flocculation: increased" EXACT [SGD:phenotype_annotation] synonym: "increased cell-cell adhesion" BROAD [PomBase:mah, PomBase:vw] synonym: "increased flocculation" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-19T02:50:53Z [Term] id: FYPO:0000156 name: abnormal chromatin silencing at silent mating-type cassette def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is abnormal." [PomBase:mah] synonym: "abnormal chromatin silencing at silent mating-type cassette during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000157 name: abnormal response to DNA damage stimulus def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to DNA damage is abnormal." [PomBase:mah] comment: Also consider specific phenotype terms for sensitivity to substances or other stimuli that can damage DNA, e.g. 'sensitive to DNA damaging agents' (FYPO:0000266), 'sensitive to methyl methanesulfonate' (FYPO:0000089), 'sensitive to UV' (FYPO:0000268), etc. synonym: "abnormal response to DNA damage stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000158 name: DNA content increased def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of DNA in a cell is greater than normal." [PomBase:mah] synonym: "DNA content increased during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000159 name: abnormal chromosome condensation alt_id: FYPO:0000028 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromosome condensation is abnormal. Chromosome condensation is the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division." [GO:0030261, PomBase:mah] synonym: "abnormal chromosome condensation during vegetative growth" EXACT [PomBase:mah] synonym: "chromosome condensation defects" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-04-14T10:44:38Z [Term] id: FYPO:0000160 name: DNA fragmentation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA is broken into small fragments." [PomBase:mah] synonym: "DNA fragmentation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000161 name: abnormal actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly is abnormal." [PomBase:mah] synonym: "abnormal actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:mah] synonym: "abnormal contractile ring assembly" EXACT [PomBase:mah] synonym: "abnormal cytokinesis, actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "abnormal cytokinetic ring assembly" NARROW [PomBase:vw] synonym: "abnormal cytokinetic ring formation" RELATED [PomBase:vw] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000162 name: abnormal cellular response to stress def: "A cellular response phenotype in which a cellular response to stress is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000163 name: abnormal autophagy alt_id: FYPO:0000379 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagy is abnormal. Autophagy is the process in which cells digest parts of their own cytoplasm." [GO:0006914, PomBase:mah] synonym: "abnormal autophagy during vegetative growth" EXACT [PomBase:mah] synonym: "autophagy: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000164 name: abnormal cytokinetic cell separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinetic cell separation is abnormal. Cell separation is the process of physically separating progeny cells during cytokinesis, and involves enzymatic digestion of septum components." [GO:0000920, PomBase:mah] synonym: "abnormal cytokinetic cell separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000165 name: abnormal regulation of conjugation def: "A regulation phenotype in which regulation of conjugation is abnormal." [PomBase:mah] synonym: "abnormal regulation of conjugation with cellular fusion" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000166 name: abnormal regulation of G2/M transition of mitotic cell cycle def: "A regulation phenotype in which negative regulation of the G2 to M transition of the mitotic cell cycle is abnormal." [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000167 name: increased DNA recombination at mitotic DNA replication fork barriers def: "A cellular process phenotype in which the frequency of DNA recombination at replication fork barriers is increased." [PomBase:mah] synonym: "DNA recombination defect, at mitotic DNA replication fork barriers, elevated" EXACT [PomBase:mah] synonym: "increased DNA recombination at mitotic DNA replication fork barriers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000168 name: abnormal mitotic cell cycle spindle assembly checkpoint def: "A cell cycle checkpoint phenotype in which the spindle assembly checkpoint of a mitotic cell cycle is abnormal. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. In a mutant, the checkpoint may fail to activate under appropriate conditions, or may occur to a greater or lesser extent than wild type under any specified set of conditions." [GO:0007094, PomBase:mah] synonym: "abnormal mitotic cell cycle spindle assembly checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0000200 ! abnormal regulation of mitotic metaphase/anaphase transition is_a: FYPO:0001704 ! abnormal cell cycle checkpoint created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000169 name: abnormal chromatin silencing at telomere def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at telomeric regions is abnormal." [PomBase:mah] synonym: "abnormal chromatin silencing at telomere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000171 name: abnormal late endosome to vacuole transport def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which late endosome to vacuole transport is abnormal." [PomBase:mah] synonym: "abnormal late endosome to vacuole transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000213 ! abnormal vesicle-mediated transport is_a: FYPO:0000597 ! abnormal vacuolar transport created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000172 name: abnormal meiotic telomere clustering def: "A meiosis phenotype in which meiotic telomere clustering is abnormal. Meiotic telomere clustering is the dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body." [GO:0045141, PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000173 name: abnormal mitotic cell cycle DNA replication checkpoint alt_id: FYPO:0000823 def: "A cell cycle checkpoint phenotype in which the DNA replication checkpoint in a mitotic cell cycle is abnormal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. In a mutant, the checkpoint may fail to activate under appropriate conditions, or may occur to a greater or lesser extent than wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal DNA replication checkpoint" BROAD [PomBase:mah] synonym: "abnormal mitotic cell cycle DNA replication checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0000166 ! abnormal regulation of G2/M transition of mitotic cell cycle is_a: FYPO:0000643 ! abnormal DNA integrity checkpoint created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000174 name: abnormal cell wall biogenesis def: "A cellular process phenotype in which cell wall biogenesis is abnormal." [PomBase:mah] synonym: "abnormal fungal-type cell wall biogenesis" EXACT [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process relationship: results_in_formation_of FYPO:0000027 ! abnormal cell wall created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000175 name: abnormal ascospore wall assembly def: "A sporulation phenotype in which ascospore wall assembly is abnormal." [PomBase:mah] synonym: "abnormal spore wall formation" RELATED [PomBase:mah] synonym: "spore wall formation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0000679 ! developmental process phenotype relationship: part_of FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000176 name: abnormal DNA replication initiation def: "A cellular process phenotype in which the initiation of DNA replication is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal DNA-dependent DNA replication initiation" EXACT [PomBase:mah] is_a: FYPO:0000217 ! abnormal DNA replication created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000177 name: abnormal mitotic spindle assembly def: "A cellular process phenotype in which assembly of the mitotic spindle is abnormal." [PomBase:mah] synonym: "abnormal mitotic spindle assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001349 ! abnormal spindle assembly during vegetative growth relationship: part_of FYPO:0000337 ! abnormal mitosis relationship: results_in_formation_of FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000178 name: abnormal regulation of cytokinesis def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of cytokinesis is abnormal." [PomBase:mah] synonym: "abnormal regulation of cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "abnormal regulation of cytokinesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000179 name: abnormal protein targeting via the multivesicular body sorting pathway def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole via the multivesicular sorting pathway, leading to ubiquitin-dependent protein degradation, is abnormal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway" EXACT [PomBase:mah] synonym: "abnormal protein targeting via the multivesicular body sorting pathway during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000171 ! abnormal late endosome to vacuole transport is_a: FYPO:0000676 ! abnormal protein targeting to vacuole created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000180 name: abnormal cellular response to oxidative stress def: "A stress response phenotype in which a cellular response to oxidative stress is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000162 ! abnormal cellular response to stress created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000181 name: abolished crossover def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which reciprocal DNA recombination does not occur." [PomBase:mah] synonym: "crossover abolished" EXACT [PomBase:mah] synonym: "crossover abolished during vegetative growth" EXACT [PomBase:mah] synonym: "DNA recombination defects, crossover, abolished" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000182 name: abnormal cell wall organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GO:0031505, PomBase:mah] synonym: "abnormal cell wall organisation" EXACT [PomBase:mah] synonym: "abnormal cell wall organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal fungal-type cell wall organization" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000183 name: abnormal poly(A)+ mRNA export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of polyadenylated mRNA from the nucleus is abnormal." [PomBase:mah] synonym: "abnormal poly(A)+ mRNA export from nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000204 ! abnormal mRNA export from nucleus created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000184 name: abnormal regulation of pseudohyphal growth def: "A regulation phenotype in which regulation of pseudohyphal growth is abnormal." [PomBase:mah] synonym: "abnormal regulation of filamentous growth" BROAD [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-13T03:34:54Z [Term] id: FYPO:0000185 name: decreased gene conversion def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which gene conversion occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased gene conversion during vegetative growth" EXACT [PomBase:mah] synonym: "DNA recombination defects, gene conversion, reduced" EXACT [PomBase:mah] synonym: "reduced gene conversion" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000186 name: abnormal cell division def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell division is abnormal." [PomBase:mah] synonym: "abnormal cell division during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000187 name: abnormal chromatin silencing by small RNA def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing mediated by small RNA is abnormal." [PomBase:mah] synonym: "abnormal chromatin silencing by small RNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000188 name: abnormal DNA repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which DNA repair is abnormal." [PomBase:mah] synonym: "abnormal DNA repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000157 ! abnormal response to DNA damage stimulus is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000189 name: abnormal nuclear mRNA splicing, via spliceosome def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome is abnormal." [PomBase:mah] synonym: "abnormal nuclear mRNA splicing, via spliceosome during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000190 name: abnormal actin cortical patch localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch localisation" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin patch localization" EXACT [PomBase:vw] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000191 name: abnormal regulation of establishment or maintenance of cell polarity def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the establishment or maintenance of cell polarity is abnormal." [PomBase:mah] synonym: "abnormal regulation of establishment or maintenance of cell polarity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000192 name: abnormal regulation of S phase of mitotic cell cycle def: "A regulation phenotype in which regulation of progression through S phase of the mitotic cell cycle is abnormal." [PomBase:mah] comment: This term was made obsolete because it was based on a GO term (GO:0007090) that has itself been made obsolete. is_obsolete: true created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000193 name: abnormal cellular response to osmotic stress def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which a cellular response to osmotic stress is abnormal." [PomBase:mah] synonym: "abnormal cellular response to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000194 name: abnormal cellular response to hydrogen peroxide def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which a cellular response to hydrogen peroxide is abnormal." [PomBase:mah] synonym: "abnormal cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001340 ! abnormal cellular response to oxidative stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000196 name: abnormal forespore formation def: "A sporulation phenotype in which prospore formation is abnormal." [PomBase:mah] synonym: "abnormal ascospore-type prospore assembly" EXACT [GO:0031321] synonym: "abnormal ascospore-type prospore formation" EXACT [PomBase:mah] synonym: "abnormal prospore formation" EXACT [PomBase:mah] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0000679 ! developmental process phenotype relationship: part_of FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000197 name: abnormal horsetail movement def: "A cellular process phenotype in which horsetail movement is abnormal. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [GO:0030989, PomBase:mah] synonym: "abnormal dynein-driven meiotic oscillatory nuclear movement" EXACT [GO:0030989, PomBase:mah] synonym: "abnormal horsetail nuclear movement" EXACT [GO:0030989, PomBase:mah] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000198 name: abnormal establishment or maintenance of actin cytoskeleton polarity def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of actin cytoskeleton polarity is abnormal." [PomBase:mah] synonym: "abnormal establishment or maintenance of actin cytoskeleton polarity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000026 ! abnormal cell polarity is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000199 name: increased long tract gene conversion def: "A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of long tract gene conversion is increased." [PomBase:mah] synonym: "DNA recombination defects, long tract gene conversion, increased" EXACT [PomBase:mah] synonym: "increased long tract gene conversion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000200 name: abnormal regulation of mitotic metaphase/anaphase transition def: "A regulation phenotype in which regulation of the mitotic metaphase to anaphase transition is abnormal." [PomBase:mah] synonym: "abnormal regulation of mitotic metaphase/anaphase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000201 name: abnormal histone deacetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone deacetylation is abnormal." [PomBase:mah] synonym: "abnormal histone deacetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000202 name: abnormal regulation of cytokinetic cell separation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of cytokinetic cell separation is abnormal." [PomBase:mah] synonym: "abnormal regulation of cytokinetic cell separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000203 name: abnormal ergosterol biosynthetic process def: "A metabolism phenotype observed in the vegetative growth phase of the life cycle in which ergosterol biosynthesis is abnormal." [PomBase:mah] synonym: "abnormal ergosterol biosynthesis" EXACT [PomBase:mah] synonym: "abnormal ergosterol biosynthetic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000204 name: abnormal mRNA export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of mRNA from the nucleus is abnormal." [PomBase:mah] synonym: "abnormal mRNA export from nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000506 ! abnormal nuclear export created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000206 name: abnormal chromatin silencing at rDNA def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at ribosomal DNA repeats is abnormal." [PomBase:mah] synonym: "abnormal chromatin silencing at rDNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000144 ! abnormal chromatin silencing created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000207 name: abnormal cellular response to caffeine def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to caffeine is abnormal." [PomBase:mah] synonym: "abnormal cellular response to caffeine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000208 name: abnormal cellular response to cadmium ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to cadmium ions is abnormal." [PomBase:mah] synonym: "abnormal cellular response to cadmium ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000209 name: abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the attachment of spindle microtubules to the kinetochore during the first meiotic division is abnormal." [PomBase:mah] synonym: "abnormal attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000211 name: abnormal cellular response to drug def: "A chemical response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a chemical is abnormal." [PomBase:mah] synonym: "abnormal cellular response to drug during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000212 name: abnormal cellular response to heat def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to heat is abnormal." [PomBase:mah] synonym: "abnormal cellular response to heat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000213 name: abnormal vesicle-mediated transport def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is abnormal." [PomBase:mah] synonym: "abnormal vesicle-mediated transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000214 name: abnormal mitotic chromosome condensation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation is abnormal." [PomBase:mah] synonym: "abnormal mitotic chromosome condensation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000159 ! abnormal chromosome condensation created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000215 name: abnormal intracellular protein transport def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which intracellular protein transport is abnormal." [PomBase:mah] synonym: "abnormal intracellular protein transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000540 ! abnormal protein transport created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000216 name: abnormal negative regulation of DNA replication initiation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, resulting in re-replication of all or part of the genome." [PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation" EXACT [PomBase:mah] synonym: "DNA re-replication" RELATED [PomBase:mah] synonym: "DNA replication defects, endoreduplication" RELATED [PomBase:mah] synonym: "DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of DNA replication initiation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000217 name: abnormal DNA replication def: "A cellular process phenotype in which DNA replication is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal DNA-dependent DNA replication" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype is_a: FYPO:0000860 ! abnormal metabolic process created_by: midori creation_date: 2011-04-13T03:41:10Z [Term] id: FYPO:0000218 name: decreased Mre11 complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of Mre11 complex assembly is reduced." [PomBase:mah] synonym: "decreased Mre11 complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "MRN complex formation, reduced" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein complex assembly created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000219 name: increased protein oxidation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins." [PomBase:mah] synonym: "accumulation of carbonylated proteins" RELATED [PomBase:mah] synonym: "increased level of disulfides" RELATED [PomBase:al] synonym: "increased level of oxidised thiols in proteins" RELATED [PomBase:al] synonym: "increased level of oxidized protein thiols" RELATED [PomBase:mah] synonym: "increased protein oxidation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000547 ! increased protein modification created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000220 name: accumulation of centromeric outer repeat transcripts def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are present at greater levels than normal." [PMID:20211136, PomBase:mah] synonym: "accumulation of centromeric outer repeat transcripts during vegetative growth" EXACT [PomBase:mah] synonym: "accumulation of non-coding outer repeat transcripts" EXACT [PomBase:vw] synonym: "accumulation of siRNAs homologous to outer repeats" EXACT [PomBase:vw] synonym: "increased centromeric outer repeat transcript level" EXACT [PomBase:mah] synonym: "increased level of centromeric outer repeat transcripts" EXACT [PomBase:mah] synonym: "increased level of siRNAs homologous to outer repeats" EXACT [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000221 name: transcription regulation phenotype, adaptive response to loss of mtDNA def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which the transcription of specific genes is regulated in response to the loss of mitochondrial DNA." [PMID:17868468, PomBase:mah] synonym: "adaptive expression responses" EXACT [PomBase:mah] synonym: "fission yeast transcription regulation phenotype, adaptive response to loss of mtDNA" EXACT [PomBase:mah] synonym: "transcription regulation phenotype, adaptive response to loss of mtDNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000223 name: elongated multiseptate cells def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which cells are elongated and have more than one septum per cell." [PomBase:mah] synonym: "elongated multiseptate cells during vegetative growth" EXACT [PomBase:mah] synonym: "long multiseptate cells" EXACT [PomBase:vw] is_a: FYPO:0000118 ! multiseptate is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000118 ! multiseptate created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000224 name: lemon-shaped def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in the form of a lemon. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc." [http://mathworld.wolfram.com/Lemon.html, PomBase:mah] synonym: "cell morphology, lemon shaped" EXACT [PomBase:mah] synonym: "lemon-shaped during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000225 name: snowman-shaped spore def: "A cell morphology phenotype in which a spore assumes a snowman shape, having two connected parts, roughly spherical, of different sizes." [PomBase:mah] synonym: "cell morphology, snowman during sporulation" RELATED [PomBase:mah] synonym: "snowman during sporulation" RELATED [PomBase:mah] is_a: FYPO:0000348 ! abnormal spore morphology created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000227 name: chromosome loss during mitotic chromosome segregation def: "A chromosome segregation phenotype observed in the vegetative growth phase of the life cycle in which one or more chromosome or minichromosome is not correctly segregated to either daughter cells during mitosis." [PMID:11809834, PMID:20211136, PomBase:mah] synonym: "chromosome loss during mitotic sister chromatid segregation" EXACT [PomBase:mah] synonym: "chromosome loss during segregation during vegetative growth" EXACT [PomBase:mah] synonym: "chromosome segregation defects, chromosome loss" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000228 name: lagging mitotic chromosomes def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which sister chromatids do not move towards the spindle poles at the same time during mitosis, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Mitotic sister chromatid segregation stops before completing separation of chromosomes." [PMID:11809834, PMID:20211136, PomBase:mah] synonym: "chromosome segregation defects, lagging mitotic chromosomes" EXACT [PomBase:mah] synonym: "lagging chromosomes during vegetative growth" EXACT [PomBase:mah] synonym: "lagging mitotic sister chromatids" EXACT [PomBase:mah] is_a: FYPO:0001271 ! incomplete, unequal mitotic sister chromatid separation is_a: FYPO:0002090 ! lagging chromosomes created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000229 name: cut alt_id: FYPO:0000322 alt_id: FYPO:0000323 def: "An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal chromosome segregation, and gives rise to inviable daughter cells." [PomBase:jh, PomBase:mah, PomBase:vw] comment: In a cut phenotype, the septum may partition the two nuclei into the two daughter cells, partition both nuclei into one daughter cell, or physically divide one nucleus, depending on septum placement. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cut during vegetative growth" EXACT [PomBase:mah] synonym: "cut, binucleate cell formation" NARROW [PomBase:mah, PomBase:vw] synonym: "cut, septum dividing nucleus" NARROW [PomBase:mah, PomBase:vw] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000230 name: abnormal contractile ring actin filament organization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filament bundles does not occur normally, resulting in the formation of an abnormal contractile ring in which actin is absent or mislocalized." [GO:2000689, PMID:19713940, PomBase:mah] synonym: "abnormal contractile ring actin filament organisation" EXACT [PomBase:mah] synonym: "abnormal contractile ring actin filament organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000727 ! abnormal actin filament organization created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000231 name: abnormal contractile ring myosin filament organization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which myosin filaments are not localized normally within the contractile ring." [GO:2000708, PMID:19713940, PomBase:mah] synonym: "abnormal contractile ring myosin filament organisation" EXACT [PomBase:mah] synonym: "abnormal contractile ring myosin filament organization during vegetative growth" EXACT [PomBase:mah] synonym: "cytokinesis defects, contractile ring myosin distribution, defective" RELATED [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000232 name: actomyosin contractile ring splitting def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the contractile ring splits upon initiation of contraction during anaphase B, resulting in the formation of a primary ring that undergoes constriction and a secondary ring that does not constrict." [PMID:18272786, PomBase:mah] synonym: "abnormal contractile ring contraction with contractile ring splitting" EXACT [PomBase:mah] synonym: "actomyosin contractile ring splitting during vegetative growth" EXACT [PomBase:mah] synonym: "actomyosin contractile ring splitting upon contraction" EXACT [PomBase:mah] synonym: "cytokinesis defects, splitting of the actinomyosin ring" RELATED [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth is_a: FYPO:0001364 ! abnormal contractile ring contraction created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000233 name: long cytoplasmic microtubules def: "A microtubule organization phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are longer than normal." [PomBase:mah] synonym: "long cytoplasmic microtubules during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule organization defect, long cytoplasmic microtubules" EXACT [PomBase:mah] synonym: "microtubule organization defects, long cytoplasmic microtubules" EXACT [PomBase:mah] is_a: FYPO:0000055 ! long microtubules created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000234 name: abnormal interphase microtubule nucleation def: "A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from interphase microtubule organizing centers (iMTOCs) is abnormal." [PMID:19001497, PomBase:mah] synonym: "abnormal interphase microtubule nucleation by interphase microtubule organizing center" EXACT [PomBase:mah] synonym: "abnormal interphase microtubule nucleation during vegetative growth" EXACT [PomBase:mah] synonym: "cytoskeletal defects, cytoplasmic microtubule nucleation defects, Non-SPB" RELATED [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000235 name: abnormal regulation of translation in response to osmotic stress def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to osmotic stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress." [PMID:18065650, PomBase:mah] synonym: "abnormal regulation of translation in response to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "defective in recovery of translation after hyperosmotic shock" RELATED [PomBase:mah] is_a: FYPO:0001332 ! abnormal regulation of translation in response to stress during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000236 name: abnormal regulation of translation in response to oxidative stress def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to oxidative stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress." [PMID:18065650, PomBase:mah] synonym: "abnormal regulation of translation in response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "defective in recovery of translation after oxidative stress" RELATED [PomBase:mah] is_a: FYPO:0001332 ! abnormal regulation of translation in response to stress during vegetative growth is_a: FYPO:0001340 ! abnormal cellular response to oxidative stress during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000237 name: abnormal regulation of translation in response to nitrogen starvation def: "A gene expression phenotype in which regulation of translation in response to nitrogen starvation is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels upon prolonged nitrogen starvation." [PMID:18065650, PomBase:mah] synonym: "defective in recovery of translation during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0000152 ! abnormal cellular response to nitrogen starvation is_a: FYPO:0000263 ! abnormal regulation of translation in response to stress created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000238 name: inviable cell upon G0 to G1 transition def: "A cell phenotype in which a cell fails to resume growth after several days in G0 phase. The inviable cells show some features characteristic of apoptosis, including loss of DNA." [PMID:19197239, PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "die in G0 with an apoptotic-like phenotype" EXACT [PomBase:mah] synonym: "essential upon G0 to G1 transition" RELATED [PomBase:mah] is_a: FYPO:0000049 ! inviable cell created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000239 name: expression of MBF target genes increased def: "A gene expression phenotype observed in the vegetative growth phase of the life cycle in which transcription of genes that are regulated by MBF (the MluI cell cycle box factor) is increased." [PomBase:mah] synonym: "expression of MBF target genes increased during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000240 name: abnormal filament morphology def: "A cell population phenotype in which the morphology of invasively growing filaments is abnormal." [PomBase:mah] synonym: "filament morphology aberrant" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000241 name: genome stability defects def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which any process that affects the physical integrity, replication, or segregation of genomic DNA is abnormal. Encompasses effects on DNA metabolism, chromosome organization, the spindle assembly checkpoint, and any DNA integrity checkpoint." [PomBase:jh, PomBase:mah, PomBase:vw] comment: Consider annotating to 'abnormal chromosome organization' (FYPO:0000641), 'DNA metabolism phenotype' (FYPO:0000293) or any of its children, 'abnormal mitotic cell cycle spindle assembly checkpoint' (FYPO:0000168), or 'abnormal DNA integrity checkpoint' (FYPO:0000643) or any of its children. synonym: "genome stability defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000242 name: normal cell population growth on ammonia nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing ammonia as the nitrogen source." [PomBase:mah] synonym: "growth defect, normal growth with ammonia nitrogen source" RELATED [PomBase:mah] synonym: "normal growth on ammonia nitrogen source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on ammonia nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000243 name: normal cell population growth on proline nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing L-proline as the nitrogen source." [PomBase:mah] synonym: "growth defect, normal growth with proline nitrogen source" RELATED [PomBase:mah] synonym: "normal growth on proline nitrogen source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on proline nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000244 name: loss of viability upon nutrient depletion def: "A cell population phenotype in which a smaller than normal proportion of the population remains viable when cells are deprived of nutrients such as carbon or nitrogen." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown under nutrient-depleted conditions, and then the number of cells viable enough to form a colony upon return to nutrient-replete conditions is measured and compared to wild type. synonym: "growth defect, required during nutrient depletion" RELATED [PomBase:mah] synonym: "loss of viability upon nutrient starvation" EXACT [PomBase:al] synonym: "sensitive to nitrogen starvation" RELATED [PomBase:al] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability relationship: includes_cells_with_phenotype FYPO:0000713 ! abnormal cellular response to starvation created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000245 name: loss of viability in stationary phase def: "A cell population phenotype in which a smaller than normal proportion of the population remains viable after entering stationary phase." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown to stationary phase, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "decreased viability in stationary phase" EXACT [PomBase:mah] synonym: "growth defect, required for stationary phase" RELATED [PomBase:mah] synonym: "reduced viability in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000246 name: antioxidant required for growth def: "A cell population phenotype in which a cell population grows only in the presence of an antioxidant in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "antioxidant required for cell population growth" EXACT [PomBase:mah] synonym: "antioxidant required for vegetative cell growth" EXACT [PomBase:mah] synonym: "growth auxotrophic for antioxidant" EXACT [PomBase:al] synonym: "growth defect, requires antioxidant for growth" EXACT [PomBase:mah] is_a: FYPO:0001356 ! abnormal vegetative cell population growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000247 name: decreased cell population growth at high temperature def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal at a high temperature." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. For fission yeast, high temperature usually corresponds to above 32 degrees Celsius. synonym: "decreased growth at high temperature" BROAD [PomBase:mah] synonym: "decreased vegetative cell population growth at high temperature" EXACT [PomBase:mah] synonym: "growth defect, slow growth at high temperatures" RELATED [PomBase:mah] synonym: "reduced growth at high temperature" RELATED [PomBase:mah] synonym: "slow growth at high temperature" RELATED [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000249 name: decreased cell population growth on ammonia nitrogen source alt_id: FYPO:0000248 def: "A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing ammonia as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on ammonia nitrogen source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on ammonia nitrogen source" EXACT [PomBase:mah] synonym: "growth defect, slow growth in minimal media" RELATED [PomBase:mah] synonym: "growth defect, slow growth with ammonia nitrogen source" NARROW [PomBase:mah] synonym: "reduced cell growth on ammonia nitrogen source" EXACT [PomBase:mah] synonym: "slow cell growth in minimal medium" RELATED [PomBase:mah] synonym: "slow cell growth on ammonia nitrogen source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000250 name: decreased cell population growth on proline nitrogen source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-proline as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on proline nitrogen source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on proline nitrogen source" EXACT [PomBase:mah] synonym: "growth defect, slow growth with proline nitrogen source" RELATED [PomBase:mah] synonym: "reduced cell growth on proline nitrogen source" RELATED [PomBase:mah] synonym: "slow cell growth on proline nitrogen source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000251 name: decreased cell population growth on galactose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing galactose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on galactose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on galactose carbon source" EXACT [PomBase:mah] synonym: "growth defects, growth inhibition in galactose-based medium" RELATED [PomBase:mah] synonym: "reduced cell growth on galactose carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on galactose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000252 name: increased spontaneous diploidization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which heterothallic haploid cells spontaneously form cells with diploid DNA content at a higher frequency than normal." [PMID:19101542, PomBase:mah] synonym: "high-frequency diploidization in heterothallic strains" EXACT [PomBase:mah] synonym: "increased spontaneous diploidization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000253 name: increased HMG-CoA reductase activity def: "A molecular function phenotype in which the observed rate of hydroxymethylglutaryl-CoA reductase (NADPH) activity is increased." [PMID:19041767, PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000254 name: increased protein processing def: "A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which the observed occurrence of protein processing is increased." [PMID:19520858, PomBase:mah] synonym: "increased protein processing during vegetative growth" EXACT [PomBase:mah] synonym: "increased Sre1 cleavage" NARROW [PomBase:mah] is_a: FYPO:0001421 ! abnormal protein processing created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000255 name: nuclear protein accumulation def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which specific proteins abnormally accumulate, and are constitutively located in, the nucleus." [PMID:12896976, PomBase:mah] synonym: "localization defects, nuclear accumulation of Pap1 and Sty1" NARROW [PomBase:mah] synonym: "nuclear accumulation of Pap1 and Sty1" NARROW [PomBase:mah] synonym: "nuclear accumulation of protein" EXACT [PomBase:mah] synonym: "nuclear protein accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000762 ! protein accumulation is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000256 name: mutator def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a higher rate than normal." [PomBase:mah] synonym: "mutator during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000257 name: normal phenotype def: "A phenotype that shows no detectable differences from normal. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast normal phenotype" EXACT [PomBase:mah] synonym: "no obvious phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype relationship: inheres_in FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000258 name: normal phenotype during exponential phase def: "A cell phenotype that shows no detectable differences from normal during exponential growth." [PomBase:mah] synonym: "fission yeast normal phenotype during exponential phase" EXACT [PomBase:mah] synonym: "no phenotype in exponential phase" EXACT [PomBase:mah] synonym: "normal phenotype during exponential phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000260 name: abnormal G1/S phase transcription def: "A gene expression phenotype in which regulation of transcription during the G1/S phase of the cell cycle is abnormal." [PomBase:mah] synonym: "abnormal G1/S phase transcription during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of transcription involved in G1/S phase of mitotic cell cycle" EXACT [PomBase:mah] synonym: "periodic cell-cycle expression, abolished" RELATED [PomBase:mah] is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000261 name: pleiotropic effects def: "Multiple different phenotypes due to a single mutation." [PomBase:mah] comment: This term was made obsolete because genes, alleles, etc. can be annotated with multiple specific phenotype terms. synonym: "pleiotropic effects during vegetative growth" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000262 name: abnormal cellular response to reactive oxygen species during G0 phase def: "A cell phenotype in which cells do not respond normally to reactive oxygen species, resulting in accumulation of oxidative damage including DNA damage, during G0 phase." [PMID:19197239, PomBase:mah] synonym: "protects against physiological oxidative damage in G0" RELATED [PomBase:mah] is_a: FYPO:0000180 ! abnormal cellular response to oxidative stress created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000263 name: abnormal regulation of translation in response to stress def: "A gene expression phenotype in which regulation of translation in response to stress is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "protein synthesis after stress, defective" RELATED [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress is_a: FYPO:0000289 ! translation regulation phenotype created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000264 name: resistance to microtubule-destabilizing substance def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of a microtubule-destabilizing substance than normal." [PomBase:mah] synonym: "resistance to microtubule depolymerizing drugs" EXACT [PomBase:mah] synonym: "resistance to microtubule destabilising substance" EXACT [PomBase:mah] synonym: "resistance to microtubule-destabilizing substance during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000265 name: sensitive to DNA damage def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to DNA damage." [PomBase:mah] comment: Also consider specific phenotype terms for sensitivity to substances or other stimuli that can damage DNA, e.g. 'sensitive to DNA damaging agents' (FYPO:0000266), 'sensitive to methyl methanesulfonate' (FYPO:0000089), 'sensitive to UV' (FYPO:0000268), etc. synonym: "hypersensitive to DNA damage" EXACT [PomBase:mah] synonym: "sensitive to DNA damage during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000157 ! abnormal response to DNA damage stimulus is_a: FYPO:0000304 ! sensitive to stress created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000266 name: sensitive to DNA damaging agents def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a genotoxin, any chemical compound that can act to induce direct or indirect DNA damage. Cells stop growing (and may die) at a concentration of a DNA damaging agent that allows wild type cells to grow." [CHEBI:50902, PomBase:mah] synonym: "hypersensitive to DNA damaging agents" EXACT [PomBase:mah] synonym: "sensitive to DNA damaging agents during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000267 name: sensitive to ionizing radiation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ionizing radiation." [PomBase:mah] synonym: "hypersensitive to ionizing radiation" EXACT [PomBase:mah] synonym: "sensitive to gamma irradiation" NARROW [PomBase:al] synonym: "sensitive to gamma radiation" NARROW [PomBase:al] synonym: "sensitive to ionizing radiation during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to IR" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000268 name: sensitive to UV def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light." [PomBase:mah] synonym: "hypersensitive to UV" EXACT [PomBase:mah] synonym: "increased sensitivity to UV irradiation" EXACT [PomBase:vw] synonym: "sensitive to ultraviolet light" EXACT [PomBase:mah] synonym: "sensitive to UV during vegetative growth" EXACT [PomBase:mah] synonym: "UV resistance: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000304 ! sensitive to stress created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000269 name: sensitive to microtubule depolymerizing drugs def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a microtubule-destabilizing substance. Cells stop growing (and may die) at a concentration of a microtubule-depolymerizing drug that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to microtubule depolymerizing drugs" EXACT [PomBase:mah] synonym: "sensitive to microtubule depolymerizing drugs during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-04-19T02:59:38Z [Term] id: FYPO:0000270 name: sensitive to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to osmotic stress." [PomBase:mah] synonym: "hypersensitive to osmotic stress" EXACT [PomBase:mah] synonym: "osmotic stress resistance: decreased" EXACT [SGD:phenotype_annotation] synonym: "sensitive to osmotic stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000193 ! abnormal cellular response to osmotic stress is_a: FYPO:0000304 ! sensitive to stress created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000271 name: sensitive to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a salt stress." [PomBase:mah] synonym: "hypersensitive to salt stress" EXACT [PomBase:mah] synonym: "ionic stress resistance: decreased" EXACT [SGD:phenotype_annotation] synonym: "sensitive to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000270 ! sensitive to osmotic stress created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000272 name: abolished septum formation def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell fails to form a septum." [PMID:9649519, PomBase:mah] synonym: "septum formation abolished" EXACT [PomBase:mah] synonym: "septum formation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "septum formation: absent" EXACT [SGD:phenotype_annotation] synonym: "septum initiation defective" RELATED [PomBase:mah] is_a: FYPO:0000117 ! abnormal septation is_a: FYPO:0000186 ! abnormal cell division is_a: FYPO:0000417 ! abolished cytokinesis created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000273 name: centromeric outer repeat transcripts absent def: "An RNA metabolism phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are absent." [PMID:20211136, PomBase:mah] synonym: "centromeric outer repeat transcripts absent during vegetative growth" EXACT [PomBase:mah] synonym: "siRNAs homologous to outer repeats absent" EXACT [PomBase:vw] synonym: "siRNAs homologous to outer repeats undetectable" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000274 name: increased duration of mitotic M phase alt_id: FYPO:0000609 def: "A cell cycle phenotype in the duration of M phase of the mitotic cell cycle is longer than normal." [PomBase:mah] synonym: "delayed mitotic M phase progression" RELATED [PomBase:mah] synonym: "delayed mitotic M phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "increased mitotic M phase duration" EXACT [PomBase:mah] synonym: "increased mitotic M phase duration during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in M phase: delayed" EXACT [SGD:phenotype_annotation] synonym: "spindle checkpoint activated" RELATED [PomBase:mah] is_a: FYPO:0000607 ! abnormal mitotic M phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000275 name: spindle checkpoint required def: "A cell cycle phenotype in which cells are viable only if a spindle checkpoint functions normally." [PMID:15483052, PomBase:mah] comment: This term was made obsolete because it was used to represent two different phenotypes. is_obsolete: true consider: FYPO:0000029 consider: FYPO:0000324 consider: FYPO:0000333 created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000276 name: monopolar mitotic spindle def: "A cellular structure phenotype in which the mitotic spindle forms with microtubules emanating from only one pole." [PMID:11792803, PMID:9763447, PomBase:mah] synonym: "monopolar mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "spindle defects, monopolar mitotic spindle" EXACT [PomBase:mah] synonym: "spindle defects, monopolar spindle" EXACT [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000278 name: decreased cell population growth following spore germination def: "A cell population phenotype in which cell population growth is decreased following spore germination, resulting in the formation of a smaller colony than normal in a given amount of time." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth following spore germination" BROAD [PomBase:mah] synonym: "reduced cell population growth following spore germination" EXACT [PomBase:mah] synonym: "slow cell population growth following spore germination" NARROW [PomBase:mah] synonym: "spores produced smaller colonies" RELATED [PomBase:mah] is_a: FYPO:0000046 ! decreased cell population growth is_a: FYPO:0000305 ! abnormal spore germination created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000279 name: formation of azygotic ascus upon sporulation def: "A sporulation phenotype in which azygotic asci form following conjugation and subsequent sporulation. Azygotic ascus formation occurs when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell." [PMID:16169489, PMID:18780734, PMID:20404563, PomBase:mah] synonym: "abnormal sporulation resulting in formation of azygotic asci" EXACT [PomBase:mah] synonym: "formation of azygotic asci upon sporulation" EXACT [PomBase:mah] synonym: "sporulation defects, azygotic asci" EXACT [PomBase:mah] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000280 name: sterile alt_id: FYPO:0000638 def: "A cellular process phenotype in which conjugation does not occur." [PomBase:mah] synonym: "conjugation abolished" EXACT [PomBase:mah] synonym: "zygote formation abolished" RELATED [PomBase:mah] is_a: FYPO:0000031 ! abnormal conjugation created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000281 name: fragmented vacuoles def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are broken into more, smaller fragments than normal." [PomBase:mah] synonym: "fragmented vacuoles during vegetative growth" EXACT [PomBase:mah] synonym: "vacuole organization defects, fragmented vacuoles" EXACT [PomBase:mah] is_a: FYPO:0000368 ! abnormal vacuolar morphology created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000282 name: viable cell at high temperature def: "A viability phenotype observed in the vegetative growth phase of the life cycle in which a cell is able to survive at a high temperature." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "cell viable at high temperature" EXACT [PomBase:mah] synonym: "viable cell at high temperature during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000283 name: mitotic chromosome fragmentation upon segregation def: "A chromosome segregation phenotype in which chromosomes are broken during mitotic chromosome segregation." [PomBase:mah] synonym: "chromosome fragmentation upon mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "chromosome fragmentation upon segregation during mitosis" EXACT [PomBase:mah] synonym: "chromosome fragmentation upon segregation during vegetative growth" EXACT [PomBase:mah] synonym: "chromosome segregation defects, chromosome fragmentation" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000284 name: large and small daughter nuclei def: "A mitosis phenotype observed in the vegetative growth phase of the life cycle in which the nucleus divides unequally to produce one daughter nucleus that is larger than the other." [PMID:8769419, PomBase:mah] synonym: "large and small daughter nuclei during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2011-04-19T04:37:01Z [Term] id: FYPO:0000286 name: sensitive to manganese depletion def: "A cell population phenotype observed in the vegetative growth phase of the life cycle in which a population of cells grow poorly in medium that has a low concentration of manganese (Mn2+)." [PMID:14723709, PomBase:mah] synonym: "hypersensitive to manganese depletion" EXACT [PomBase:mah] synonym: "sensitive to manganese depletion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001356 ! abnormal vegetative cell population growth created_by: midori creation_date: 2011-04-20T01:42:21Z [Term] id: FYPO:0000287 name: abnormal subcellular structure def: "A cellular structure phenotype in which the amount, distribution, or morphology of a cell part is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate is_a: FYPO:0000136 ! cellular structure phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-04-21T11:18:18Z [Term] id: FYPO:0000288 name: gene expression regulation phenotype def: "A regulation phenotype that affects the regulation of gene expression." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast gene expression regulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0000145 ! regulation phenotype created_by: midori creation_date: 2011-04-21T02:22:36Z [Term] id: FYPO:0000289 name: translation regulation phenotype def: "A gene expression phenotype that affects the regulation of translation." [PomBase:mah] synonym: "fission yeast translation regulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000288 ! gene expression regulation phenotype created_by: midori creation_date: 2011-04-21T02:25:06Z [Term] id: FYPO:0000290 name: transcription phenotype def: "A cellular process phenotype that affects DNA-dependent transcription." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast transcription phenotype" EXACT [PomBase:mah] synonym: "transcription phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0000294 ! RNA metabolism phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000291 name: translation phenotype def: "A cellular process phenotype that affects translation." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast translation phenotype" EXACT [PomBase:mah] synonym: "translation phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000292 name: nucleic acid metabolism phenotype def: "A cellular process phenotype that affects any nucleic acid metabolic process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast nucleic acid metabolism phenotype" EXACT [PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000293 name: DNA metabolism phenotype def: "A cellular process phenotype that affects any DNA metabolic process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast DNA metabolism phenotype" EXACT [PomBase:mah] is_a: FYPO:0000292 ! nucleic acid metabolism phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000294 name: RNA metabolism phenotype def: "A cellular process phenotype that affects any RNA metabolic process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast RNA metabolism phenotype" EXACT [PomBase:mah] synonym: "RNA metabolism phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000295 name: cytoskeleton organization phenotype def: "A cellular process phenotype that affects cytoskeleton organization. Cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GO:0007010, PomBase:mah] synonym: "cytoskeleton organisation phenotype" EXACT [PomBase:mah] synonym: "fission yeast cytoskeleton organization phenotype" EXACT [PomBase:mah] is_a: FYPO:0000334 ! cellular component organization phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000296 name: actin cytoskeleton organization phenotype def: "A cellular process phenotype that affects the organization of the actin cytoskeleton. Actin cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and associated proteins." [GO:0030036, PomBase:mah] comment: Consider annotating to 'abnormal actin cytoskeleton morphology' (FYPO:0000350), but note that an abnormal cytoskeleton organization process may, but does not necessarily, result in abnormal cytoskeleton morphology. synonym: "actin cytoskeleton organisation phenotype" EXACT [PomBase:mah] synonym: "actin cytoskeleton organization phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast actin cytoskeleton organization phenotype" EXACT [PomBase:mah] is_a: FYPO:0000295 ! cytoskeleton organization phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000297 name: microtubule cytoskeleton organization phenotype def: "A cellular process phenotype that affects the organization of the microtubule cytoskeleton. Microtubule cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and associated proteins." [GO:0000226, PomBase:mah] synonym: "fission yeast microtubule cytoskeleton organization phenotype" EXACT [PomBase:mah] synonym: "microtubule cytoskeleton organisation phenotype" EXACT [PomBase:mah] is_a: FYPO:0000295 ! cytoskeleton organization phenotype created_by: midori creation_date: 2011-04-21T02:31:20Z [Term] id: FYPO:0000298 name: cellular response phenotype def: "A cellular process phenotype that affects a response to a stimulus." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast cellular response phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-21T04:47:15Z [Term] id: FYPO:0000299 name: microcolony formation def: "A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few cells." [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype relationship: comprises_cells_with_phenotype FYPO:0000049 ! inviable cell created_by: midori creation_date: 2011-04-26T02:13:39Z [Term] id: FYPO:0000300 name: biological process phenotype def: "A phenotype that affects a biological process." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast biological process phenotype" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-04-26T02:25:13Z [Term] id: FYPO:0000301 name: mating phenotype def: "A biological process phenotype that affects conjugation." [PomBase:mah] synonym: "conjugation phenotype" EXACT [PomBase:mah] synonym: "fission yeast mating phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-04-26T02:29:20Z [Term] id: FYPO:0000302 name: abnormal response to pheromone def: "A conjugation phenotype in which a cell's response to mating pheromone is abnormal." [PomBase:mah] synonym: "abnormal response to pheromone involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "defective response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-04-26T02:36:20Z [Term] id: FYPO:0000303 name: decreased conjugation frequency def: "A conjugation phenotype in which conjugation occurs less frequently than normal." [PomBase:mah] comment: Note that this term refers specifically to conjugation, whereas experiments that measure mating efficiency often do so by counting zygotes plus asci, sometimes also including spores. For such experiments, we recommend using 'decreased mating efficiency' (FYPO:0000708). synonym: "decreased conjugation efficiency" EXACT [PomBase:mah] synonym: "decreased occurrence of conjugation" EXACT [PomBase:mah] synonym: "reduced conjugation efficiency" EXACT [PomBase:mah] synonym: "reduced conjugation frequency" EXACT [PomBase:mah] synonym: "reduced zygote formation" RELATED [PomBase:mah] is_a: FYPO:0000031 ! abnormal conjugation created_by: midori creation_date: 2011-04-26T02:40:00Z [Term] id: FYPO:0000304 name: sensitive to stress def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a stress." [PomBase:mah] synonym: "hypersensitive to stress" EXACT [PomBase:mah] synonym: "sensitive to stress during vegetative growth" EXACT [PomBase:mah] synonym: "stress resistance: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2011-04-26T03:10:44Z [Term] id: FYPO:0000305 name: abnormal spore germination def: "A cellular process phenotype in which spore germination is abnormal." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000306 name: abolished spore germination def: "A cellular process phenotype in which spore germination does not occur." [PomBase:mah] synonym: "inviable spore" EXACT [PomBase:jh, PomBase:mah] synonym: "spore germination abolished" EXACT [PomBase:mah] is_a: FYPO:0000305 ! abnormal spore germination created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000307 name: spore germination abolished, small spores def: "A cellular process phenotype in which spore germination does not occur, and spores are smaller than normal." [PomBase:mah] is_a: FYPO:0000309 ! spore germination abolished, abnormal spore morphology relationship: has_part FYPO:0000306 ! abolished spore germination relationship: has_part FYPO:0000346 ! small spores created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000308 name: spore germination abolished, swollen spores def: "A cellular process phenotype in which spore germination does not occur, and spores have a larger volume than normal." [PomBase:mah] is_a: FYPO:0000309 ! spore germination abolished, abnormal spore morphology relationship: has_part FYPO:0000306 ! abolished spore germination relationship: has_part FYPO:0000347 ! swollen spores created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000309 name: spore germination abolished, abnormal spore morphology def: "A cellular process phenotype in which spore germination does not occur, and spores have abnormal morphology." [PomBase:mah] synonym: "spore germination abolished, misshapen spores" EXACT [PomBase:mah] is_a: FYPO:0000306 ! abolished spore germination relationship: has_part FYPO:0000306 ! abolished spore germination relationship: has_part FYPO:0000348 ! abnormal spore morphology created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000310 name: inviable after spore germination with normal germ tube morphology def: "A phenotype in which a spore germinates to produce a normal germ tube, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "essential; germinating spore with normal germ tube morphology" RELATED [PomBase:mah] synonym: "inviable following spore germination with normal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinating spore with normal germ tube morphology" RELATED [PomBase:mah] is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000311 name: inviable after spore germination with normal, unseptated germ tube morphology def: "A phenotype in which a spore germinates to produce a normal germ tube, but does not septate or go on to form a viable dividing cell." [PomBase:mah] synonym: "essential; germinating spore with normal, unseptated germ tube morphology" RELATED [PomBase:mah] synonym: "inviable following spore germination with normal, unseptated germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinating spore with normal, unseptated germ tube morphology" RELATED [PomBase:mah] is_a: FYPO:0000310 ! inviable after spore germination with normal germ tube morphology created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000312 name: inviable after spore germination with normal, septated germ tube morphology def: "A phenotype in which a spore germinates to produce a normal germ tube, and undergoes septation, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "essential; germinating spore with normal, septated germ tube morphology" RELATED [PomBase:mah] synonym: "inviable following spore germination with normal, septated germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinating spore with normal, septated germ tube morphology" RELATED [PomBase:mah] is_a: FYPO:0000310 ! inviable after spore germination with normal germ tube morphology created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000313 name: inviable after spore germination with abnormal germ tube morphology def: "A phenotype in which a spore germinates to produce a germ tube with abnormal morphology, and does not go on to form a viable dividing cell." [PomBase:mah] synonym: "essential; germinating spore with abnormal germ tube morphology" RELATED [PomBase:mah] synonym: "inviable following spore germination with abnormal germ tube morphology" EXACT [PomBase:mah] synonym: "inviable germinating spore with abnormal germ tube morphology" RELATED [PomBase:mah] is_a: FYPO:0000348 ! abnormal spore morphology is_a: FYPO:0001118 ! abnormal vegetative cell morphology is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth is_a: FYPO:0001991 ! inviable after spore germination, without cell division created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000314 name: inviable after spore germination with elongated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and does not go on to form a viable dividing cell." [PomBase:mah] synonym: "essential; germinating spore with elongated germ tube" RELATED [PomBase:mah] synonym: "inviable following spore germination with elongated germ tube" EXACT [PomBase:mah] synonym: "inviable germinating spore with elongated germ tube" RELATED [PomBase:mah] synonym: "inviable germinating spore with long germ tube" EXACT [PomBase:vw] is_a: FYPO:0000313 ! inviable after spore germination with abnormal germ tube morphology is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0001123 ! elongated spore created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000315 name: inviable after spore germination with elongated, septated germ tube def: "A phenotype in which a spore germinates to produce an elongated germ tube, and undergoes septation, but does not go on to form a viable dividing cell." [PomBase:mah] synonym: "essential; germinating spore with elongated, septated germ tube" RELATED [PomBase:mah] synonym: "inviable following spore germination with elongated, septated germ tube" EXACT [PomBase:mah] synonym: "inviable germinating spore with elongated, septated germ tube" RELATED [PomBase:mah] synonym: "inviable germinating spore with long, septated germ tube" EXACT [PomBase:vw] is_a: FYPO:0000313 ! inviable after spore germination with abnormal germ tube morphology created_by: midori creation_date: 2011-04-27T11:47:04Z [Term] id: FYPO:0000316 name: inviable after spore germination def: "A viability phenotype in which a spore germinates but fails to produce dividing cells that can survive under normal conditions." [PomBase:jh, PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "essential in germinating spore" RELATED [PomBase:mah] synonym: "inviable after spore germination" EXACT [PomBase:mah] synonym: "inviable germinating spore" RELATED [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2011-04-27T01:13:41Z [Term] id: FYPO:0000317 name: mixed population def: "A cell population phenotype in which a population contains cells with more than one phenotype, usually different morphologies." [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype created_by: midori creation_date: 2011-04-27T01:32:52Z [Term] id: FYPO:0000318 name: inviable mixed population including long cells def: "A mixed population phenotype in which a microcolony forms, and all cells in the population divide once upon spore germination but are inviable, and some cells are longer than normal." [PomBase:jh, PomBase:mah] comment: Consider also annotating to 'elongated inviable vegetative cell' (FYPO:0001490) or one of its descendants, to describe the phenotype of the individual elongated cells in the population. synonym: "essential; mixed population including long cells" RELATED [PomBase:mah] synonym: "long low penetrance" EXACT [PomBase:jh, PomBase:vw] is_a: FYPO:0000299 ! microcolony formation is_a: FYPO:0000317 ! mixed population relationship: includes_cells_with_phenotype FYPO:0000017 ! elongated cell created_by: midori creation_date: 2011-04-27T04:18:16Z [Term] id: FYPO:0000319 name: inviable mixed population including spores and divided germinated spores def: "A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of spores and germinated spores most of which go on to divide once or twice. Some germinated spores remain septated and do not complete cell division." [PomBase:jh, PomBase:mah] synonym: "essential; mixed population including spores and divided germinated spores" RELATED [PomBase:mah] synonym: "put cut" RELATED [PomBase:jh] is_a: FYPO:0000317 ! mixed population relationship: comprises_cells_with_phenotype FYPO:0000049 ! inviable cell relationship: includes_cells_with_phenotype FYPO:0000306 ! abolished spore germination relationship: includes_cells_with_phenotype FYPO:0000320 ! inviable after spore germination, single cell division created_by: midori creation_date: 2011-04-27T04:20:40Z [Term] id: FYPO:0000320 name: inviable after spore germination, single cell division def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes a single round of cell division, and then dies." [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "essential; germinating spore, single cell division" RELATED [PomBase:mah] synonym: "inviable following spore germination, single cell division" EXACT [PomBase:mah] synonym: "inviable germinating spore, single cell division" RELATED [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination created_by: midori creation_date: 2011-04-27T04:25:13Z [Term] id: FYPO:0000321 name: inviable mixed population including spores and undivided germinated spores def: "A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores and germinated spores that fail to divide." [PomBase:jh, PomBase:mah] synonym: "essential; mixed population including spores and undivided germinated spores" RELATED [PomBase:mah] is_a: FYPO:0000317 ! mixed population relationship: comprises_cells_with_phenotype FYPO:0000049 ! inviable cell relationship: includes_cells_with_phenotype FYPO:0000316 ! inviable after spore germination created_by: midori creation_date: 2011-04-27T04:32:25Z [Term] id: FYPO:0000324 name: mitotic metaphase/anaphase transition delay alt_id: FYPO:0000393 def: "A cell cycle phenotype in which the onset of anaphase of the mitotic cell cycle takes place later than normal." [PomBase:mah] synonym: "cell cycle passage through the metaphase-anaphase transition: delayed" EXACT [SGD:phenotype_annotation] synonym: "delayed cell cycle passage through mitotic metaphase-anaphase transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle delay at metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "mitotic metaphase/anaphase transition delay during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-05-09T04:36:10Z [Term] id: FYPO:0000325 name: abnormal attachment of spindle microtubules to kinetochore def: "A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division is abnormal." [PomBase:mah] synonym: "abnormal attachment of spindle microtubules to kinetochore during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-05-11T01:50:15Z [Term] id: FYPO:0000326 name: abnormal sister chromatid biorientation def: "A cellular process phenotype in which the stable attachment of sister chromatids to microtubules emanating from opposite poles of the mitotic spindle is abnormal." [PomBase:mah] synonym: "abnormal sister chromatid biorientation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000325 ! abnormal attachment of spindle microtubules to kinetochore is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2011-05-11T01:51:05Z [Term] id: FYPO:0000327 name: resistance to trichostatin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of trichostatin A than normal." [PomBase:mah] synonym: "resistance to trichostatin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to trichostatin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-05-11T02:55:53Z [Term] id: FYPO:0000328 name: abnormal protein metabolic process def: "A cellular process phenotype that affects protein metabolism in the cell." [PomBase:mah] synonym: "abnormal cellular protein metabolic process" EXACT [PomBase:mah] synonym: "abnormal protein metabolic process during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-05-11T03:39:46Z [Term] id: FYPO:0000329 name: abnormal protein modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] synonym: "abnormal protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000328 ! abnormal protein metabolic process created_by: midori creation_date: 2011-05-11T03:40:46Z [Term] id: FYPO:0000330 name: abnormal histone modification def: "A cellular process phenotype that affects histone modification." [PomBase:mah] synonym: "abnormal histone modification during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2011-05-11T03:41:32Z [Term] id: FYPO:0000331 name: decreased histone acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone acetylation" EXACT [PomBase:mah] is_a: FYPO:0000456 ! abnormal histone acetylation created_by: midori creation_date: 2011-05-11T03:42:20Z [Term] id: FYPO:0000332 name: increased histone acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000456 ! abnormal histone acetylation created_by: midori creation_date: 2011-05-11T03:43:21Z [Term] id: FYPO:0000333 name: mitotic G1/S transition delay alt_id: FYPO:0000396 alt_id: FYPO:0000480 alt_id: FYPO:0000543 def: "A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle takes place later than normal. The duration of G1 phase is thus longer than normal." [PomBase:mah] comment: A G1/S delay may indicate that a checkpoint, such as the cell size checkpoint or the G1/S DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants. synonym: "cell cycle progression through the G1/S phase transition: delayed" EXACT [SGD:phenotype_annotation] synonym: "delayed cell cycle progression through mitotic G1/S phase transition" EXACT [PomBase:mah] synonym: "delayed mitotic G1 phase progression" RELATED [PomBase:mah] synonym: "increased duration of mitotic G1 phase" EXACT [PomBase:mah] synonym: "increased duration of mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic G1 phase progression" EXACT [PomBase:mah] synonym: "mitotic cell cycle delay at G1/S transition" EXACT [PomBase:mah] synonym: "mitotic cell cycle delay in G1" RELATED [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: delayed" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in G1 phase: increased duration" EXACT [SGD:phenotype_annotation] synonym: "mitotic G1/S transition delay during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000394 ! abnormal cell cycle progression through mitotic G1/S phase transition is_a: FYPO:0000409 ! delayed cell cycle phase transition is_a: FYPO:0000602 ! abnormal mitotic G1 phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-05-11T04:08:59Z [Term] id: FYPO:0000334 name: cellular component organization phenotype def: "A phenotype that affects a process of cellular component organization, i.e. the assembly, arrangement of constituent parts, or disassembly of a cellular component, that occurs at the cellular level." [PomBase:mah] synonym: "cellular component organisation phenotype" EXACT [PomBase:mah] synonym: "cellular component organization phenotype at cellular level" EXACT [PomBase:mah] synonym: "fission yeast cellular component organization phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-06-03T11:55:29Z [Term] id: FYPO:0000335 name: abnormal cellular component organization def: "A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal." [GO:0071842, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular component organisation" EXACT [PomBase:mah] synonym: "abnormal cellular component organization at cellular level" EXACT [PomBase:mah] is_a: FYPO:0000334 ! cellular component organization phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-06-03T11:57:14Z [Term] id: FYPO:0000336 name: abnormal cellular component assembly def: "A cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular component assembly at cellular level" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2011-06-03T12:00:35Z [Term] id: FYPO:0000337 name: abnormal mitosis def: "A cellular process phenotype in which mitosis is abnormal." [PomBase:mah] synonym: "abnormal mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000607 ! abnormal mitotic M phase progression created_by: midori creation_date: 2011-06-03T12:29:47Z [Term] id: FYPO:0000338 name: abnormal mitotic spindle alt_id: FYPO:0000277 def: "A cellular structure phenotype in which the structure of the mitotic spindle is abnormal." [PomBase:mah] synonym: "abnormal mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic spindle defects" EXACT [PomBase:mah] synonym: "spindle polarity defects" RELATED [PomBase:mah] is_a: FYPO:0000120 ! abnormal spindle is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-06-03T01:43:41Z [Term] id: FYPO:0000339 name: mislocalized septum def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum in an abnormal location. The normal location is at the midpoint of the long axis of the cell." [PomBase:mah] comment: Note that the location of the septum is determined by the location of the contractile ring, which in turn is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. synonym: "abnormal barrier septum site selection" RELATED [PomBase:mah] synonym: "abnormal septum localization" RELATED [PomBase:mah] synonym: "abnormal septum location" EXACT [PomBase:mah] synonym: "abnormal septum position" EXACT [PomBase:mah] synonym: "abnormal septum positioning" RELATED [PomBase:mah] synonym: "asymmetric septum" EXACT [PomBase:mah] synonym: "asymmetrically located septum" EXACT [PomBase:mah] synonym: "mislocalised septum" EXACT [PomBase:mah] synonym: "mislocalized septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2011-06-13T02:57:21Z [Term] id: FYPO:0000340 name: haploinsufficient def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a single functional copy of a gene does not provide sufficient normal function in a diploid cell." [PomBase:mah] synonym: "haploinsufficient during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2011-06-13T04:23:38Z [Term] id: FYPO:0000341 name: haplosufficient def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a single functional copy of a gene provides sufficient normal function in a diploid cell." [PomBase:mah] synonym: "haploproficient" EXACT [PomBase:mah] synonym: "haplosufficient during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2011-06-13T04:25:07Z [Term] id: FYPO:0000342 name: decreased cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular respiration is decreased." [PomBase:mah] synonym: "decreased cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "decreased respiration" BROAD [PomBase:mah] synonym: "decreased respiratory metabolism" EXACT [PomBase:mah] synonym: "reduced cellular respiration" EXACT [PomBase:mah] synonym: "respiratory metabolism: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2011-06-14T04:25:19Z [Term] id: FYPO:0000343 name: increased hydrogen sulfide biosynthesis def: "A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of hydrogen sulfide is increased." [PomBase:mah] synonym: "increased H2S biosynthesis " EXACT [PomBase:mah] synonym: "increased hydrogen sulfide biosynthesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth relationship: has_output FYPO:0001413 ! increased cellular sulfide level created_by: midori creation_date: 2011-06-14T04:44:26Z [Term] id: FYPO:0000344 name: enlarged nucleus def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is larger than normal." [PomBase:mah] synonym: "enlarged nuclei" EXACT [PomBase:vw] synonym: "enlarged nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology created_by: midori creation_date: 2011-06-15T03:45:06Z [Term] id: FYPO:0000345 name: abnormal protein export from nucleus def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of protein from the nucleus is abnormal. Export of all proteins or a specific protein may be affected." [PomBase:mah] comment: Encompasses both export of proteins normally retained in the nucleus and nuclear retention of normally exported proteins. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein export from nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport is_a: FYPO:0000506 ! abnormal nuclear export created_by: midori creation_date: 2011-06-15T05:11:00Z [Term] id: FYPO:0000346 name: small spores def: "A cell morphology phenotype in which spores have an abnormally low volume." [PomBase:mah] is_a: FYPO:0000023 ! small cell is_a: FYPO:0000348 ! abnormal spore morphology created_by: midori creation_date: 2011-07-07T03:26:17Z [Term] id: FYPO:0000347 name: swollen spores def: "A cell morphology phenotype in which a spore has a larger volume than normal." [PomBase:mah] is_a: FYPO:0000025 ! swollen cell is_a: FYPO:0000348 ! abnormal spore morphology created_by: midori creation_date: 2011-07-07T03:34:09Z [Term] id: FYPO:0000348 name: abnormal spore morphology def: "A cell phenotype characterized by altered spore morphology." [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology relationship: output_of FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-07-07T03:35:26Z [Term] id: FYPO:0000349 name: abnormal Golgi morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the Golgi apparatus is abnormal." [PomBase:mah] comment: Note that an abnormal Golgi organization process may, but does not necessarily, result in abnormal Golgi morphology. synonym: "abnormal Golgi morphology during vegetative growth" EXACT [PomBase:mah] synonym: "Golgi morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000353 ! abnormal endomembrane system morphology relationship: output_of FYPO:0000806 ! abnormal Golgi organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000350 name: abnormal actin cytoskeleton morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the actin cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in abnormal actin cytoskeleton morphology. synonym: "abnormal actin cytoskeleton morphology during vegetative growth" EXACT [PomBase:mah] synonym: "actin cytoskeleton morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000352 ! abnormal cytoskeleton morphology relationship: output_of FYPO:0000801 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000351 name: abnormal cell wall morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the fungal-type cell wall is abnormal." [PomBase:mah] synonym: "abnormal cell wall morphology during vegetative growth" EXACT [PomBase:mah] synonym: "cell wall morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000027 ! abnormal cell wall created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000352 name: abnormal cytoskeleton morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal cytoskeleton organization process may, but does not necessarily, result in abnormal cytoskeleton morphology. synonym: "abnormal cytoskeleton morphology during vegetative growth" EXACT [PomBase:mah] synonym: "cytoskeleton morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000802 ! abnormal cytoskeleton organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000353 name: abnormal endomembrane system morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of all or part of the endomembrane system is abnormal." [PomBase:mah] comment: Note that an abnormal endomembrane system organization process may, but does not necessarily, result in abnormal endomembrane system morphology. synonym: "abnormal endomembrane system morphology during vegetative growth" EXACT [PomBase:mah] synonym: "endomembrane system morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000804 ! abnormal endomembrane system organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000354 name: abnormal endoplasmic reticulum morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the endoplasmic reticulum is abnormal." [PomBase:mah] comment: Note that an abnormal endoplasmic reticulum organization process may, but does not necessarily, result in abnormal endoplasmic reticulum morphology. synonym: "abnormal endoplasmic reticulum morphology during vegetative growth" EXACT [PomBase:mah] synonym: "endoplasmic reticulum morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000353 ! abnormal endomembrane system morphology relationship: output_of FYPO:0000805 ! abnormal endoplasmic reticulum organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000355 name: normal endoplasmic reticulum morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the endoplasmic reticulum is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "endoplasmic reticulum morphology: normal" EXACT [SGD:phenotype_annotation] synonym: "normal endoplasmic reticulum morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular structure during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000356 name: abnormal lipid particle morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of lipid particles is abnormal." [PomBase:mah] comment: Note that an abnormal lipid particle organization process may, but does not necessarily, result in abnormal lipid particle morphology. synonym: "abnormal lipid particle morphology during vegetative growth" EXACT [PomBase:mah] synonym: "lipid particle morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000808 ! abnormal lipid particle organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000357 name: abnormal shmoo morphology def: "A cellular structure phenotype in which the morphology of the mating projection is abnormal." [PomBase:mah] synonym: "abnormal conjugation tube morphology" EXACT [PomBase:mah] synonym: "abnormal mating projection morphology" EXACT [PomBase:mah] synonym: "mating projection morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000287 ! abnormal subcellular structure relationship: output_of FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000358 name: mating projection absent def: "A cellular structure phenotype in which cells do not form mating projections." [PomBase:mah] synonym: "absent mating projection morphology" EXACT [PomBase:mah] synonym: "mating projection morphology: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000287 ! abnormal subcellular structure is_a: FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000359 name: abnormal mitochondrial morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the mitochondrion is abnormal." [PomBase:mah] comment: Note that an abnormal mitochondrion organization process may, but does not necessarily, result in abnormal mitochondrial morphology. synonym: "abnormal mitochondrial morphology during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000809 ! abnormal mitochondrion organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000360 name: abnormal RNA localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA localization is abnormal." [PomBase:mah] synonym: "abnormal RNA localisation" EXACT [PomBase:mah] synonym: "abnormal RNA localization during vegetative growth" EXACT [PomBase:mah] synonym: "RNA localization: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000361 name: abnormal nucleolar morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the nucleolus is abnormal." [PomBase:mah] comment: Note that an abnormal nucleolus organization process may, but does not necessarily, result in abnormal nucleolar morphology. synonym: "abnormal nucleolar morphology during vegetative growth" EXACT [PomBase:mah] synonym: "nucleolar morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000814 ! abnormal nucleolus organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000362 name: abnormal peroxisomal morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the peroxisome is abnormal." [PomBase:mah] comment: Note that an abnormal peroxisome organization process may, but does not necessarily, result in abnormal peroxisome morphology. synonym: "abnormal peroxisomal morphology during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000811 ! abnormal peroxisome organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000363 name: peroxisomes absent def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain peroxisomes." [PomBase:mah] synonym: "absent peroxisomal morphology" EXACT [PomBase:mah] synonym: "peroxisomal morphology: absent" EXACT [SGD:phenotype_annotation] synonym: "peroxisomes absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000364 name: abnormal plasma membrane morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the plasma membrane is abnormal." [PomBase:mah] comment: Note that an abnormal plasma membrane organization process may, but does not necessarily, result in abnormal plasma membrane morphology. synonym: "abnormal plasma membrane morphology during vegetative growth" EXACT [PomBase:mah] synonym: "plasma membrane morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000813 ! abnormal plasma membrane organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000365 name: small nucleus def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is smaller than normal." [PomBase:mah] synonym: "size of nucleus: decreased" EXACT [SGD:phenotype_annotation] synonym: "small nuclei" EXACT [PomBase:vw] synonym: "small nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000366 name: decreased RNA localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA localization is decreased." [PomBase:mah] synonym: "decreased RNA localisation" EXACT [PomBase:mah] synonym: "decreased RNA localization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA localization" EXACT [PomBase:mah] synonym: "RNA localization: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000360 ! abnormal RNA localization created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000368 name: abnormal vacuolar morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the fungal-type vacuole is abnormal." [PomBase:mah] comment: Note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. synonym: "abnormal vacuolar morphology during vegetative growth" EXACT [PomBase:mah] synonym: "vacuolar morphology: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000812 ! abnormal vacuole organization created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000369 name: vacuoles absent def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain vacuoles." [PomBase:mah] synonym: "absent vacuolar morphology" EXACT [PomBase:mah] synonym: "vacuolar morphology: absent" EXACT [SGD:phenotype_annotation] synonym: "vacuoles absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2011-07-14T05:04:23Z [Term] id: FYPO:0000370 name: abnormal RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA modification is abnormal. All RNA modification may be abnormal, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "abnormal RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "RNA modification: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000371 name: abolished RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA modification does not occur. All RNA modification may be abolished, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "absent RNA modification" EXACT [PomBase:mah] synonym: "RNA modification abolished" EXACT [PomBase:mah] synonym: "RNA modification abolished during vegetative growth" EXACT [PomBase:mah] synonym: "RNA modification: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000372 name: decreased RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA modification is decreased. All RNA modification may be decreased, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "decreased RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA modification" EXACT [PomBase:mah] synonym: "RNA modification: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000373 name: decreased rate of RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of RNA modification is decreased." [PomBase:mah] synonym: "decreased rate of RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of RNA modification" EXACT [PomBase:mah] synonym: "RNA modification: decreased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000374 name: increased RNA modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA modification is increased. All RNA modification may be increased, or one or more specific RNA modifications may be selectively affected." [PomBase:mah] synonym: "increased RNA modification during vegetative growth" EXACT [PomBase:mah] synonym: "RNA modification: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000370 ! abnormal RNA modification created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000375 name: abolished apoptosis def: "A cellular process phenotype in which apoptosis does not occur. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "absent apoptosis" EXACT [PomBase:mah] synonym: "apoptosis abolished" EXACT [PomBase:mah] synonym: "apoptosis: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000629 ! abnormal apoptosis created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000376 name: decreased apoptosis def: "A cellular process phenotype in which the occurrence of apoptosis is decreased. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "apoptosis: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced apoptosis" EXACT [PomBase:mah] is_a: FYPO:0000629 ! abnormal apoptosis created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000377 name: increased apoptosis def: "A cellular process phenotype in which the occurrence of apoptosis is increased. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "apoptosis: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000629 ! abnormal apoptosis created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000378 name: normal apoptosis def: "A cellular process phenotype in which apoptosis is normal (i.e. indistinguishable from wild type). Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] synonym: "apoptosis: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000380 name: abolished autophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagy does not occur." [PomBase:mah] synonym: "absent autophagy" EXACT [PomBase:mah] synonym: "autophagy abolished" EXACT [PomBase:mah] synonym: "autophagy abolished during vegetative growth" EXACT [PomBase:mah] synonym: "autophagy: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000163 ! abnormal autophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000381 name: decreased autophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophagy is decreased." [PomBase:mah] synonym: "autophagy: decreased" EXACT [SGD:phenotype_annotation] synonym: "decreased autophagy during vegetative growth" EXACT [PomBase:mah] synonym: "reduced autophagy" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal autophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000382 name: decreased rate of autophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of autophagy is decreased." [PomBase:mah] synonym: "autophagy: decreased rate" EXACT [SGD:phenotype_annotation] synonym: "decreased rate of autophagy during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of autophagy" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal autophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000383 name: delayed autophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagy is delayed." [PomBase:mah] synonym: "autophagy: delayed" EXACT [SGD:phenotype_annotation] synonym: "delayed autophagy during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal autophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000384 name: increased autophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophagy is increased." [PomBase:mah] synonym: "autophagy: increased" EXACT [SGD:phenotype_annotation] synonym: "increased autophagy during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000163 ! abnormal autophagy created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000385 name: normal autophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagy is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "autophagy: normal" EXACT [SGD:phenotype_annotation] synonym: "normal autophagy during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000386 name: abolished biofilm formation def: "A cellular process phenotype in which biofilm formation does not occur." [PomBase:mah] synonym: "absent biofilm formation" EXACT [PomBase:mah] synonym: "biofilm formation abolished" EXACT [PomBase:mah] synonym: "biofilm formation: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000630 ! abnormal biofilm formation created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000387 name: decreased biofilm formation def: "A cellular process phenotype in which the occurrence of biofilm formation is decreased." [PomBase:mah] synonym: "biofilm formation: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced biofilm formation" EXACT [PomBase:mah] is_a: FYPO:0000630 ! abnormal biofilm formation created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000388 name: increased biofilm formation def: "A cellular process phenotype in which the occurrence of biofilm formation is increased." [PomBase:mah] synonym: "biofilm formation: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000630 ! abnormal biofilm formation created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000389 name: mitotic cell cycle arrest at START def: "A cellular process phenotype in which traversing the start control point of the mitotic cell cycle is arrested." [PomBase:mah] synonym: "cell cycle passage through START: arrested" EXACT [SGD:phenotype_annotation] synonym: "mitotic cell cycle arrest at START during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000390 name: advanced passage through START of mitotic cell cycle def: "A cellular process phenotype in which traversing the start control point of the mitotic cell cycle takes place earlier than normal." [PomBase:mah] synonym: "advanced mitotic cell cycle passage through START" EXACT [PomBase:mah] synonym: "advanced passage through START of mitotic cell cycle during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle passage through START: increased rate" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000148 ! abnormal regulation of mitotic cell cycle is_a: FYPO:0000827 ! advanced cell cycle progression created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000391 name: normal passage through START of mitotic cell cycle def: "A cellular process phenotype in which traversing the start control point of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "cell cycle passage through START: normal" EXACT [SGD:phenotype_annotation] synonym: "normal mitotic cell cycle passage through START" EXACT [PomBase:mah] synonym: "normal passage through START of mitotic cell cycle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001928 ! normal regulation of mitotic cell cycle created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000392 name: cell cycle arrest at mitotic metaphase/anaphase transition def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the metaphase/anaphase transition." [PomBase:mah] synonym: "abnormal cell cycle arrest at mitotic metaphase/anaphase transition" EXACT [PomBase:mah] synonym: "cell cycle arrest at mitotic metaphase/anaphase transition during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle passage through the metaphase-anaphase transition: arrested" EXACT [SGD:phenotype_annotation] synonym: "mitotic metaphase/anaphase arrest" EXACT [PomBase:mah] is_a: FYPO:0000608 ! mitotic cell cycle arrest in M phase created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000394 name: abnormal cell cycle progression through mitotic G1/S phase transition def: "A cellular process phenotype in which the G1/S transition of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal cell cycle progression through mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle progression through the G1/S phase transition: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000395 name: mitotic cell cycle arrest at G1/S phase transition def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the G1/S transition." [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest at G1/S phase transition" EXACT [PomBase:mah] synonym: "cell cycle progression through the G1/S phase transition: arrested" EXACT [SGD:phenotype_annotation] synonym: "mitotic cell cycle arrest at G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic G1/S phase arrest" EXACT [PomBase:mah] is_a: FYPO:0000394 ! abnormal cell cycle progression through mitotic G1/S phase transition is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000397 name: decreased duration of cell cycle progression through mitotic G1/S phase transition def: "A cellular process phenotype in which the duration of progression through the G1/S transition of the mitotic cell cycle is shorter than normal." [PomBase:mah] synonym: "cell cycle progression through the G1/S phase transition: increased rate" RELATED [SGD:phenotype_annotation] synonym: "decreased duration of cell cycle progression through mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of cell cycle progression through mitotic G1/S phase transition" RELATED [PomBase:mah] synonym: "reduced duration of cell cycle progression through mitotic G1/S phase transition" EXACT [PomBase:mah] is_a: FYPO:0000394 ! abnormal cell cycle progression through mitotic G1/S phase transition is_a: FYPO:0000410 ! decreased duration of cell cycle phase created_by: midori creation_date: 2011-07-14T06:06:09Z [Term] id: FYPO:0000398 name: premature cell cycle progression through mitotic G1/S phase transition def: "A cellular process phenotype in which progression through the G1/S transition of the mitotic cell cycle is premature." [PomBase:mah] synonym: "cell cycle progression through the G1/S phase transition: premature" EXACT [SGD:phenotype_annotation] synonym: "premature cell cycle progression through mitotic G1/S phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000394 ! abnormal cell cycle progression through mitotic G1/S phase transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000399 name: abnormal cell cycle progression through mitotic G2/M phase transition def: "A cellular process phenotype in which the G2/M transition of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal cell cycle progression through mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000400 name: cell cycle arrest at mitotic G2/M phase transition def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the G2/M transition." [PomBase:mah] synonym: "abnormal cell cycle arrest at mitotic G2/M phase transition" EXACT [PomBase:mah] synonym: "cell cycle arrest at mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: arrested" EXACT [SGD:phenotype_annotation] synonym: "mitotic G2/M phase arrest" EXACT [PomBase:mah] is_a: FYPO:0000399 ! abnormal cell cycle progression through mitotic G2/M phase transition is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000402 name: increased cell cycle progression through mitotic G2/M phase transition def: "A cellular process phenotype in which the occurrence of progression through the G2/M transition of the mitotic cell cycle is increased." [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: increased" EXACT [SGD:phenotype_annotation] synonym: "increased cell cycle progression through mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000399 ! abnormal cell cycle progression through mitotic G2/M phase transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000403 name: increased duration of cell cycle progression through mitotic G2/M phase transition def: "A cellular process phenotype in which the duration of progression through the G2/M transition of the mitotic cell cycle is increased." [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: increased duration" EXACT [SGD:phenotype_annotation] synonym: "increased duration of cell cycle progression through mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000399 ! abnormal cell cycle progression through mitotic G2/M phase transition is_a: FYPO:0000408 ! increased duration of cell cycle phase created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000404 name: decreased duration of cell cycle progression through mitotic G2/M phase transition def: "A cellular process phenotype in which the duration of progression through the G2/M transition of the mitotic cell cycle is shorter than normal." [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: increased rate" EXACT [SGD:phenotype_annotation] synonym: "decreased duration of cell cycle progression through mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of cell cycle progression through mitotic G2/M phase transition" RELATED [PomBase:mah] synonym: "reduced duration of cell cycle progression through mitotic G2/M phase transition" EXACT [PomBase:mah] is_a: FYPO:0000399 ! abnormal cell cycle progression through mitotic G2/M phase transition is_a: FYPO:0000410 ! decreased duration of cell cycle phase created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000405 name: normal cell cycle progression through mitotic G2/M phase transition def: "A cellular process phenotype in which the G2/M transition of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "cell cycle progression through the G2/M phase transition: normal" EXACT [SGD:phenotype_annotation] synonym: "normal cell cycle progression through mitotic G2/M phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000411 ! normal cell cycle progression created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000407 name: abnormally arrested cell cycle progression def: "A cellular process phenotype in which cell cycle progression is arrested under conditions where arrest does not normally occur." [PomBase:mah] comment: Note that this term should be used only for cell cycle arrest that occurs in mutants but not in wild type cells. For phenotypes affecting cell cycle that normally occurs, e.g. in response to mating pheromone, see 'normally arrested cell cycle progression' (FYPO:0001025), 'abnormal occurrence of normal cell cycle arrest' (FYPO:0001026), and their child terms. synonym: "abnormal cell cycle arrest" EXACT [PomBase:mah] synonym: "abnormally arrested cell cycle progression during vegetative growth" EXACT [PomBase:mah] synonym: "cell cycle progression: arrested" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0001024 ! cell cycle arrest phenotype is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000408 name: increased duration of cell cycle phase def: "A cellular process phenotype in which the duration of one or more cell cycle phases is longer than normal." [PomBase:mah] synonym: "cell cycle progression: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "decreased rate of cell cycle progression" RELATED [PomBase:mah] synonym: "increased duration of cell cycle phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of cell cycle progression" RELATED [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000409 name: delayed cell cycle phase transition def: "A cellular process phenotype in which one or more cell cycle phase transitions takes place later than normal." [PomBase:mah] synonym: "cell cycle progression: delayed" EXACT [SGD:phenotype_annotation] synonym: "delayed cell cycle phase transition during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000410 name: decreased duration of cell cycle phase def: "A cellular process phenotype in which the duration of one or more cell cycle phases is shorter than normal." [PomBase:mah] synonym: "cell cycle progression: increased rate" RELATED [SGD:phenotype_annotation] synonym: "decreased duration of cell cycle phase during vegetative growth" EXACT [PomBase:mah] synonym: "increased rate of cell cycle progression" RELATED [PomBase:mah] synonym: "reduced duration of cell cycle phase" EXACT [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000411 name: normal cell cycle progression def: "A cellular process phenotype in which cell cycle progression is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "cell cycle progression: normal" EXACT [SGD:phenotype_annotation] synonym: "normal cell cycle progression during vegetative growth" EXACT [PomBase:mah] synonym: "normal cell-division cycle" EXACT [GO:0007049, PomBase:mah] is_a: FYPO:0000631 ! cell cycle phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000412 name: abnormal cell fusion def: "A cellular process phenotype in which plasma membrane fusion is abnormal." [PomBase:mah] synonym: "cell fusion: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001013 ! abnormal membrane organization created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000413 name: abolished cell fusion def: "A cellular process phenotype in which plasma membrane fusion does not occur." [PomBase:mah] synonym: "absent cell fusion" EXACT [PomBase:mah] synonym: "cell fusion abolished" EXACT [PomBase:mah] synonym: "cell fusion: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000412 ! abnormal cell fusion created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000414 name: decreased cell fusion def: "A cellular process phenotype in which the occurrence of plasma membrane fusion is decreased." [PomBase:mah] synonym: "cell fusion: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced cell fusion" EXACT [PomBase:mah] is_a: FYPO:0000412 ! abnormal cell fusion created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000415 name: decreased mitotic sister chromatid segregation def: "A cellular process phenotype in which the occurrence of mitotic sister chromatid segregation is decreased." [PomBase:mah] synonym: "chromosome segregation: decreased" BROAD [SGD:phenotype_annotation] synonym: "decreased chromosome segregation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic chromosome segregation" EXACT [GO:0000070] synonym: "reduced mitotic sister chromatid segregation" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000416 name: premature mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation occurs prematurely." [PomBase:mah] synonym: "chromosome segregation: premature" BROAD [SGD:phenotype_annotation] synonym: "premature chromosome segregation during vegetative growth" EXACT [PomBase:mah] synonym: "premature mitotic chromosome segregation" EXACT [GO:0000070] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000417 name: abolished cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell cycle cytokinesis does not occur." [PomBase:mah] synonym: "absent cytokinesis" EXACT [PomBase:mah] synonym: "cytokinesis abolished" EXACT [PomBase:mah] synonym: "cytokinesis abolished during vegetative growth" EXACT [PomBase:mah] synonym: "cytokinesis: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000032 ! abnormal cytokinesis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000418 name: decreased cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cell cycle cytokinesis is decreased." [PomBase:mah] synonym: "cytokinesis: decreased" EXACT [SGD:phenotype_annotation] synonym: "decreased cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000419 name: decreased rate of cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of cell cycle cytokinesis is decreased." [PomBase:mah] synonym: "cytokinesis: decreased rate" EXACT [SGD:phenotype_annotation] synonym: "decreased rate of cytokinesis during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000420 name: delayed cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell cycle cytokinesis is delayed." [PomBase:mah] synonym: "cytokinesis: delayed" EXACT [SGD:phenotype_annotation] synonym: "delayed cytokinesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000421 name: endocytosis abolished def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis does not occur." [PomBase:mah] synonym: "abolished actin-mediated endocytosis" EXACT [PomBase:vw] synonym: "absent endocytosis" EXACT [PomBase:mah] synonym: "endocytosis abolished during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000034 ! abnormal endocytosis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000422 name: decreased endocytosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of endocytosis is decreased." [PomBase:mah] synonym: "decreased endocytosis during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced actin-mediated endocytosis" EXACT [PomBase:vw] synonym: "reduced endocytosis" EXACT [PomBase:mah] is_a: FYPO:0000034 ! abnormal endocytosis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000423 name: decreased rate of endocytosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of endocytosis is decreased." [PomBase:mah] synonym: "decreased rate of actin-mediated endocytosis" EXACT [PomBase:vw] synonym: "decreased rate of endocytosis during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis: decreased rate" EXACT [SGD:phenotype_annotation] synonym: "reduced rate of endocytosis" EXACT [PomBase:mah] is_a: FYPO:0000034 ! abnormal endocytosis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000424 name: delayed endocytosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is delayed." [PomBase:mah] synonym: "delayed actin-mediated endocytosis" EXACT [PomBase:vw] synonym: "delayed endocytosis during vegetative growth" EXACT [PomBase:mah] synonym: "endocytosis: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000034 ! abnormal endocytosis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000425 name: increased endocytosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of endocytosis is increased." [PomBase:mah] synonym: "endocytosis: increased" EXACT [SGD:phenotype_annotation] synonym: "increased actin-mediated endocytosis" EXACT [PomBase:vw] synonym: "increased endocytosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000034 ! abnormal endocytosis created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000426 name: normal endocytosis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "endocytosis: normal" EXACT [SGD:phenotype_annotation] synonym: "normal endocytosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000427 name: abnormal G1 to G0 transition def: "A cellular process phenotype in which the G1 to G0 transition is abnormal." [PomBase:mah] synonym: "abnormal cell cycle quiescence" RELATED [GO:0070314, PomBase:mah] synonym: "abnormal establishment of cell quiescence" EXACT [GO:0070314, PomBase:mah] synonym: "abnormal G1/G0 transition" EXACT [GO:0070314, PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000428 name: abolished entry into G0 def: "A cellular process phenotype in which the G1 to G0 transition does not occur." [PomBase:mah] synonym: "cell cycle quiescence abolished" RELATED [GO:0070314, PomBase:mah] synonym: "entry into G0 abolished" EXACT [PomBase:mah] synonym: "establishment of cell quiescence abolished" EXACT [GO:0070314, PomBase:mah] synonym: "G1/G0 transition abolished" EXACT [GO:0070314, PomBase:mah] is_a: FYPO:0000427 ! abnormal G1 to G0 transition created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000429 name: delayed G0 to G1 transition def: "A cellular process phenotype in which the G0 to G1 transition is abnormal." [PomBase:mah] synonym: "delayed cell cycle quiescence" RELATED [GO:0070314, PomBase:mah] synonym: "delayed establishment of cell quiescence" EXACT [GO:0070314, PomBase:mah] synonym: "delayed G1/G0 transition" EXACT [GO:0070314, PomBase:mah] synonym: "slow cell growth following nitrogen starvation" RELATED [PomBase:al] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000430 name: abnormal fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation is abnormal." [PomBase:mah] synonym: "abnormal fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal fermentative metabolism" EXACT [PomBase:mah] synonym: "fermentative metabolism: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000431 name: abolished fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation does not occur." [PomBase:mah] synonym: "absent fermentative metabolism" EXACT [PomBase:mah] synonym: "fermentation abolished" EXACT [PomBase:mah] synonym: "fermentation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "fermentative metabolism abolished" EXACT [PomBase:mah] synonym: "fermentative metabolism: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000430 ! abnormal fermentation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000432 name: decreased fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of fermentation is decreased." [PomBase:mah] synonym: "decreased fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased fermentative metabolism" EXACT [PomBase:mah] synonym: "fermentative metabolism: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced fermentation" EXACT [PomBase:mah] is_a: FYPO:0000430 ! abnormal fermentation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000433 name: increased fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of fermentation is increased." [PomBase:mah] synonym: "fermentative metabolism: increased" EXACT [SGD:phenotype_annotation] synonym: "increased fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "increased fermentative metabolism" EXACT [PomBase:mah] is_a: FYPO:0000430 ! abnormal fermentation created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000434 name: normal fermentation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "fermentative metabolism: normal" EXACT [SGD:phenotype_annotation] synonym: "normal fermentation during vegetative growth" EXACT [PomBase:mah] synonym: "normal fermentative metabolism" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process created_by: midori creation_date: 2011-07-14T06:45:37Z [Term] id: FYPO:0000440 name: sensitive to antimycin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to antimycin A. Cells stop growing (and may die) at a concentration of antimycin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to antimycin A" EXACT [PomBase:mah] synonym: "sensitive to antimycin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-08-03T04:41:43Z [Term] id: FYPO:0000441 name: resistance to antimycin A def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of antimycin than normal." [PomBase:mah] synonym: "resistance to antimycin A during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to antimycin A" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-08-03T04:41:43Z [Term] id: FYPO:0000442 name: decreased cell population growth on glycerol/ethanol carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol and ethanol as the carbon sources." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased cell growth on glycerol plus ethanol" EXACT [PomBase:mah] synonym: "decreased growth on glycerol/ethanol carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on glycerol/ethanol carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on glycerol/ethanol carbon source" RELATED [PomBase:mah] synonym: "slow cell growth on glycerol/ethanol carbon source" NARROW [PomBase:mah] is_a: FYPO:0000684 ! decreased cell population growth on glycerol carbon source created_by: midori creation_date: 2011-08-03T05:18:32Z [Term] id: FYPO:0000443 name: abnormal protein localization during vegetative growth def: "A cell phenotype that affects the localization of a protein in a cell in the vegetative growth phase of the life cycle. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] comment: We recommend using one of the more specific terms instead of annotating to this term directly, if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abnormal cellular protein localisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular protein localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localisation during vegetative growth" EXACT [PomBase:mah] synonym: "protein/peptide distribution: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2011-08-04T04:19:46Z [Term] id: FYPO:0000444 name: cell cycle arrest with replicated DNA def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have replicated genomic DNA." [PomBase:mah] comment: Arrest with replicated DNA may occur between late S and G2/M; if only DNA content is measured, the arrest point cannot be determined with greater precision. synonym: "cell cycle arrest with 2C DNA content" NARROW [PomBase:mah] synonym: "cell cycle arrest with replicated DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000407 ! abnormally arrested cell cycle progression created_by: midori creation_date: 2011-08-12T02:03:05Z [Term] id: FYPO:0000445 name: cell cycle arrest in mitotic G1 phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G1 phase." [PomBase:mah] comment: Note that this term should be used only for cell cycle arrest that occurs in mutants. For phenotypes affecting the G1 cell cycle that normally occurs in response to mating pheromone, see 'abnormal cell cycle arrest in response to pheromone' (FYPO:0000530) and its child terms. synonym: "cell cycle arrest in mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: arrested" EXACT [SGD:phenotype_annotation] synonym: "mitotic G1 phase arrest" EXACT [PomBase:mah] is_a: FYPO:0000837 ! cell cycle arrest in mitotic interphase is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2011-08-12T02:07:59Z [Term] id: FYPO:0000446 name: cell cycle arrest in mitotic G2 phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G2 phase." [PomBase:mah] synonym: "cell cycle arrest in mitotic G2 phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G2 phase: arrested" EXACT [SGD:phenotype_annotation] synonym: "mitotic G2 phase arrest" EXACT [PomBase:mah] is_a: FYPO:0000837 ! cell cycle arrest in mitotic interphase is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2011-08-12T02:11:06Z [Term] id: FYPO:0000447 name: abnormal protein complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of protein complex assembly at the cellular level is abnormal." [PomBase:mah] synonym: "abnormal protein complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2011-08-12T02:26:26Z [Term] id: FYPO:0000448 name: abnormal MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is abnormal." [PomBase:mah] synonym: "abnormal MCM complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000447 ! abnormal protein complex assembly created_by: midori creation_date: 2011-08-12T02:27:22Z [Term] id: FYPO:0000449 name: abnormal protein localization to centromere def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the centromere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to centromere" EXACT [PomBase:mah] synonym: "abnormal protein localisation to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2011-08-12T02:29:38Z [Term] id: FYPO:0000450 name: decreased protein localization to centromere def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to centromere" EXACT [PomBase:mah] synonym: "decreased protein localisation to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "decreased protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "reduced protein localization to centromere" EXACT [PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere created_by: midori creation_date: 2011-08-12T02:33:53Z [Term] id: FYPO:0000451 name: increased protein localization to centromere def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to centromere" EXACT [PomBase:mah] synonym: "increased protein localisation to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "increased protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0000449 ! abnormal protein localization to centromere created_by: midori creation_date: 2011-08-12T02:34:10Z [Term] id: FYPO:0000452 name: abnormal protein localization to chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to chromatin during vegetative growth" EXACT [GO:0071168, PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001679 ! abnormal protein localization to chromatin created_by: midori creation_date: 2011-08-12T02:35:06Z [Term] id: FYPO:0000453 name: DNA content decreased def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains less DNA than normal." [PomBase:mah] synonym: "DNA content decreased during vegetative growth" EXACT [PomBase:mah] synonym: "DNA content reduced" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2011-08-12T02:37:29Z [Term] id: FYPO:0000454 name: inviable mixed population including long and short cells def: "A mixed population phenotype in which a microcolony forms, all cells in the population are inviable, and some cells are longer and other cells smaller than normal." [PomBase:mah] synonym: "essential; mixed population including long and short cells" RELATED [PomBase:mah] is_a: FYPO:0000299 ! microcolony formation is_a: FYPO:0000317 ! mixed population relationship: includes_cells_with_phenotype FYPO:0000017 ! elongated cell relationship: includes_cells_with_phenotype FYPO:0000023 ! small cell created_by: midori creation_date: 2011-08-12T02:39:05Z [Term] id: FYPO:0000455 name: accumulation of double-strand break sites def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of double-strand breaks in DNA is greater than normal." [PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of Rad22 foci' (FYPO:0000972). synonym: "accumulation of DNA damage foci" EXACT [PomBase:mah] synonym: "accumulation of double-strand break sites during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of DNA damage foci" EXACT [PomBase:mah] synonym: "increased number of double-strand break sites" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2011-08-12T02:44:35Z [Term] id: FYPO:0000456 name: abnormal histone acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation is abnormal." [PomBase:mah] synonym: "abnormal histone acetylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification created_by: midori creation_date: 2011-08-12T02:55:54Z [Term] id: FYPO:0000457 name: abnormal histone methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered." [PomBase:mah] synonym: "abnormal histone methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000330 ! abnormal histone modification created_by: midori creation_date: 2011-08-12T02:56:38Z [Term] id: FYPO:0000458 name: abnormal histone H3-K9 methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] synonym: "abnormal histone H3-K9 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9me" EXACT [GO:0051567, PomBase:mah] synonym: "abnormal histone lysine H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation created_by: midori creation_date: 2011-08-12T02:57:59Z [Term] id: FYPO:0000459 name: abnormal mitotic centromeric sister chromatid cohesion def: "A cellular process phenotype in which cohesion between centromeres of sister chromatids is abnormal during mitosis." [PomBase:mah] synonym: "abnormal centromeric sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid cohesion, centromeric" EXACT [GO:0071962, PomBase:mah] synonym: "abnormal sister chromatid cohesion at centromere during mitosis" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth relationship: part_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-08-12T03:12:26Z [Term] id: FYPO:0000460 name: decreased mitotic centromeric sister chromatid cohesion def: "A cellular process phenotype in which cohesion between centromeres of sister chromatids is decreased during mitosis." [PomBase:mah] synonym: "decreased centromeric sister chromatid cohesion during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mitotic sister chromatid cohesion, centromeric" EXACT [GO:0071962, PomBase:mah] synonym: "decreased sister chromatid cohesion at centromere during mitosis" EXACT [PomBase:mah] synonym: "reduced mitotic centromeric sister chromatid cohesion" EXACT [PomBase:mah] is_a: FYPO:0000459 ! abnormal mitotic centromeric sister chromatid cohesion created_by: midori creation_date: 2011-08-12T03:14:23Z [Term] id: FYPO:0000461 name: flocculation abolished def: "A cellular process phenotype in which flocculation does not occur." [PomBase:mah] synonym: "absent flocculation" EXACT [PomBase:mah] synonym: "flocculation: absent" EXACT [SGD:phenotype_annotation] is_obsolete: true created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000463 name: normal flocculation def: "A cellular process phenotype in which flocculation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "flocculation: normal" EXACT [SGD:phenotype_annotation] is_obsolete: true created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000464 name: decreased intracellular transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of intracellular transport is decreased." [PomBase:mah] synonym: "decreased intracellular transport during vegetative growth" EXACT [PomBase:mah] synonym: "intracellular transport: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced intracellular transport" EXACT [PomBase:mah] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000466 name: decreased invasive growth def: "A cellular process phenotype in which the occurrence of invasive growth is decreased." [PomBase:mah] comment: This term was made obsolete because it is not required to describe fission yeast. synonym: "invasive growth: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced invasive growth" EXACT [PomBase:mah] is_obsolete: true consider: FYPO:0000552 created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000467 name: increased invasive growth def: "A cellular process phenotype in which the occurrence of invasive growth is increased." [PomBase:mah] comment: This term was made obsolete because it is not required to describe fission yeast. synonym: "invasive growth: increased" EXACT [SGD:phenotype_annotation] is_obsolete: true consider: FYPO:0000553 created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000468 name: abnormal mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching is abnormal." [PomBase:mah] synonym: "abnormal mating type switching during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000469 name: abolished mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching does not occur." [PomBase:mah] synonym: "absent mating type switching" EXACT [PomBase:mah] synonym: "mating type switching abolished" EXACT [PomBase:mah] synonym: "mating type switching abolished during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000468 ! abnormal mating type switching created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000470 name: decreased mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mating type switching is decreased." [PomBase:mah] synonym: "decreased mating type switching during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced mating type switching" EXACT [PomBase:mah] is_a: FYPO:0000468 ! abnormal mating type switching created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000471 name: increased mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mating type switching is increased." [PomBase:mah] synonym: "increased mating type switching during vegetative growth" EXACT [PomBase:mah] synonym: "mating type switching: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000468 ! abnormal mating type switching created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000472 name: normal mating type switching def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mating type switching: normal" EXACT [SGD:phenotype_annotation] synonym: "normal mating type switching during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0000859 ! normal metabolic process is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-08-12T04:05:34Z [Term] id: FYPO:0000473 name: increased mitotic recombination def: "A cellular process phenotype in which the occurrence of mitotic recombination is increased." [PomBase:mah] synonym: "increased mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000481 ! abnormal mitotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000474 name: abolished meiosis def: "A cellular process phenotype in which meiosis does not occur." [PomBase:mah] synonym: "absent meiosis" EXACT [PomBase:mah] synonym: "meiosis abolished" EXACT [PomBase:mah] synonym: "meiosis: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000475 name: arrested meiosis def: "A cellular process phenotype in which meiosis is arrested." [PomBase:mah] synonym: "meiosis: arrested" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000476 name: decreased meiosis def: "A cellular process phenotype in which the occurrence of meiosis is decreased." [PomBase:mah] synonym: "meiosis: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced meiosis" EXACT [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000477 name: delayed meiosis def: "A cellular process phenotype in which meiosis is delayed." [PomBase:mah] synonym: "meiosis: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000478 name: normal meiosis def: "A cellular process phenotype in which meiosis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "meiosis: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000479 name: premature meiosis def: "A cellular process phenotype in which meiosis occurs prematurely." [PomBase:mah] synonym: "meiosis: premature" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000051 ! abnormal meiosis created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000481 name: abnormal mitotic recombination def: "A cellular process phenotype in which mitotic recombination is abnormal." [PomBase:mah] synonym: "abnormal mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001345 ! abnormal DNA recombination during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000482 name: decreased mitotic recombination def: "A cellular process phenotype in which the occurrence of mitotic recombination is decreased." [PomBase:mah] synonym: "decreased mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced mitotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000481 ! abnormal mitotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000483 name: increased rate of mitotic recombination def: "A cellular process phenotype in which the rate of mitotic recombination is increased." [PomBase:mah] synonym: "increased rate of mitotic recombination during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic recombination: increased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000481 ! abnormal mitotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000484 name: abolished meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination does not occur." [PomBase:mah] synonym: "absent meiotic recombination" EXACT [PomBase:mah] synonym: "meiotic recombination abolished" EXACT [PomBase:mah] synonym: "meiotic recombination: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000485 name: decreased meiotic recombination def: "A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is decreased." [PomBase:mah] synonym: "meiotic recombination: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced meiotic recombination" EXACT [PomBase:mah] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000486 name: delayed meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination is delayed." [PomBase:mah] synonym: "meiotic recombination: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000487 name: increased meiotic recombination def: "A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is increased." [PomBase:mah] synonym: "meiotic recombination: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000008 ! abnormal meiotic recombination created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000488 name: normal meiotic recombination def: "A cellular process phenotype in which reciprocal meiotic recombination is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "meiotic recombination: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000293 ! DNA metabolism phenotype is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000489 name: abnormal mitochondrial distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion distribution is abnormal." [PomBase:mah] synonym: "abnormal mitochondrial distribution during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial distribution: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000809 ! abnormal mitochondrion organization is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000490 name: abnormal mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance is abnormal." [PomBase:mah] synonym: "abnormal mitochondrial genome maintenance during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000809 ! abnormal mitochondrion organization created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000491 name: abolished mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance does not occur." [PomBase:mah] synonym: "absent mitochondrial genome maintenance" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance abolished" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance abolished during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000490 ! abnormal mitochondrial genome maintenance created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000492 name: decreased mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial genome maintenance is decreased." [PomBase:mah] synonym: "decreased mitochondrial genome maintenance during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced mitochondrial genome maintenance" EXACT [PomBase:mah] is_a: FYPO:0000490 ! abnormal mitochondrial genome maintenance created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000493 name: increased mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial genome maintenance is increased." [PomBase:mah] synonym: "increased mitochondrial genome maintenance during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial genome maintenance: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000490 ! abnormal mitochondrial genome maintenance created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000494 name: normal mitochondrial genome maintenance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitochondrial genome maintenance: normal" EXACT [SGD:phenotype_annotation] synonym: "normal mitochondrial genome maintenance during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000495 name: abnormal mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial transport is abnormal." [PomBase:mah] synonym: "abnormal mitochondrial transport during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial transport: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000496 name: decreased mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial transport is decreased." [PomBase:mah] synonym: "decreased mitochondrial transport during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial transport: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced mitochondrial transport" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000495 ! abnormal mitochondrial transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000497 name: decreased rate of mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of mitochondrial transport is decreased." [PomBase:mah] synonym: "decreased rate of mitochondrial transport during vegetative growth" EXACT [PomBase:mah] synonym: "mitochondrial transport: decreased rate" EXACT [SGD:phenotype_annotation] synonym: "reduced rate of mitochondrial transport" EXACT [PomBase:mah] is_a: FYPO:0000495 ! abnormal mitochondrial transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000498 name: normal mitochondrial transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitochondrial transport: normal" EXACT [SGD:phenotype_annotation] synonym: "normal mitochondrial transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000499 name: abolished mitophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitophagy does not occur." [PomBase:mah] synonym: "absent mitophagy" EXACT [PomBase:mah] synonym: "mitophagy abolished" EXACT [PomBase:mah] synonym: "mitophagy abolished during vegetative growth" EXACT [PomBase:mah] synonym: "mitophagy: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000380 ! abolished autophagy created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000500 name: decreased mitophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitophagy is decreased." [PomBase:mah] synonym: "decreased mitophagy during vegetative growth" EXACT [PomBase:mah] synonym: "mitophagy: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced mitophagy" EXACT [PomBase:mah] is_a: FYPO:0000381 ! decreased autophagy created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000501 name: increased mitophagy def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitophagy is increased." [PomBase:mah] synonym: "increased mitophagy during vegetative growth" EXACT [PomBase:mah] synonym: "mitophagy: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000384 ! increased autophagy created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000502 name: abnormally arrested mitotic cell cycle def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested under conditions where arrest does not normally occur." [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest" RELATED [PomBase:mah] synonym: "abnormally arrested mitotic cell cycle during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle abnormally arrested" EXACT [PomBase:mah] synonym: "mitotic cell cycle: arrested" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0000407 ! abnormally arrested cell cycle progression created_by: midori creation_date: 2011-08-15T10:19:32Z [Term] id: FYPO:0000503 name: normal mitotic recombination def: "A cellular process phenotype in which mitotic recombination is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitotic recombination: normal" EXACT [SGD:phenotype_annotation] synonym: "normal mitotic recombination during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000504 name: decreased necrotic cell death def: "A cellular process phenotype in which the occurrence of necrotic cell death is decreased. Necrotic cell death is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [GO:0070265, PomBase:mah] comment: This term was made obsolete because necrotic cell death has not been observed in fission yeast. synonym: "necrotic cell death: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced necrotic cell death" EXACT [PomBase:mah] is_obsolete: true created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000505 name: increased necrotic cell death def: "A cellular process phenotype in which the occurrence of necrotic cell death is increased. Necrotic cell death is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents." [GO:0070265, PomBase:mah] comment: This term was made obsolete because necrotic cell death has not been observed in fission yeast. synonym: "necrotic cell death: increased" EXACT [SGD:phenotype_annotation] is_obsolete: true created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000506 name: abnormal nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export is abnormal. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "abnormal nuclear export during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000518 ! abnormal nuclear transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000507 name: abolished nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export does not occur. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "absent nuclear export" EXACT [PomBase:mah] synonym: "nuclear export abolished" EXACT [PomBase:mah] synonym: "nuclear export abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000506 ! abnormal nuclear export created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000508 name: decreased nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of nuclear export is decreased. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "decreased nuclear export during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced nuclear export" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000506 ! abnormal nuclear export created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000509 name: normal nuclear export def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export is normal (i.e. indistinguishable from wild type). Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "normal nuclear export during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000510 name: abnormal nuclear fusion during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion is abnormal." [PomBase:mah] synonym: "abnormal karyogamy" EXACT [PomBase:mah] synonym: "abnormal karyogamy involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "nuclear fusion during mating: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000511 name: abolished nuclear fusion during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur." [PomBase:mah] synonym: "absent nuclear fusion during mating" EXACT [PomBase:mah] synonym: "karyogamy abolished" EXACT [PomBase:mah] synonym: "karyogamy involved in conjugation with cellular fusion abolished" EXACT [PomBase:mah] synonym: "nuclear fusion during mating abolished" EXACT [PomBase:mah] synonym: "nuclear fusion during mating: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000510 ! abnormal nuclear fusion during mating created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000512 name: decreased nuclear fusion during mating def: "A cellular process phenotype in which the occurrence of karyogamy involved in conjugation with cellular fusion is decreased." [PomBase:mah] synonym: "decreased karyogamy" EXACT [PomBase:mah] synonym: "decreased karyogamy involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "nuclear fusion during mating: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced nuclear fusion during mating" EXACT [PomBase:mah] is_a: FYPO:0000510 ! abnormal nuclear fusion during mating created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000513 name: delayed nuclear fusion during mating def: "A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion is delayed." [PomBase:mah] synonym: "delayed karyogamy" EXACT [PomBase:mah] synonym: "delayed karyogamy involved in conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "nuclear fusion during mating: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000510 ! abnormal nuclear fusion during mating created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000514 name: abolished nuclear import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear import does not occur. Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "absent nuclear import" EXACT [PomBase:mah] synonym: "nuclear import abolished" EXACT [PomBase:mah] synonym: "nuclear import abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear import: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001217 ! abnormal nuclear import created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000515 name: decreased nuclear import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of nuclear import is decreased. Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "decreased nuclear import during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear import: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced nuclear import" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0001217 ! abnormal nuclear import created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000516 name: normal nuclear import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear import is normal (i.e. indistinguishable from wild type). Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "normal nuclear import during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear import: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000517 name: abnormal nucleus localization def: "A cellular process phenotype in which nucleus localization is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal nuclear localization" EXACT [PomBase:mah] synonym: "abnormal nucleus localisation" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000518 name: abnormal nuclear transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear transport is abnormal." [PomBase:mah] synonym: "abnormal nuclear transport during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear transport: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000519 name: decreased oxidative phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidative phosphorylation is decreased." [PomBase:mah] synonym: "decreased oxidative phosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "oxidative phosphorylation: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced oxidative phosphorylation" EXACT [PomBase:mah] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000520 name: increased oxidative phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidative phosphorylation is increased." [PomBase:mah] synonym: "increased oxidative phosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "oxidative phosphorylation: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000521 name: abnormal peroxisome localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisome localization is abnormal." [PomBase:mah] synonym: "abnormal peroxisomal distribution" EXACT [PomBase:mah] synonym: "abnormal peroxisome localisation" EXACT [PomBase:mah] synonym: "abnormal peroxisome localization during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal distribution: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000522 name: abnormal peroxisomal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisomal transport is abnormal." [PomBase:mah] synonym: "abnormal peroxisomal transport during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal transport: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000523 name: abolished peroxisomal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisomal transport does not occur." [PomBase:mah] synonym: "absent peroxisomal transport" EXACT [PomBase:mah] synonym: "peroxisomal transport abolished" EXACT [PomBase:mah] synonym: "peroxisomal transport abolished during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal transport: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000522 ! abnormal peroxisomal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000524 name: decreased peroxisomal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of peroxisomal transport is decreased." [PomBase:mah] synonym: "decreased peroxisomal transport during vegetative growth" EXACT [PomBase:mah] synonym: "peroxisomal transport: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced peroxisomal transport" EXACT [PomBase:mah] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000522 ! abnormal peroxisomal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000525 name: abolished peroxisome degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which pexophagy does not occur." [PomBase:mah] synonym: "absent pexophagy" EXACT [PomBase:mah] synonym: "peroxisome degradation abolished" EXACT [PomBase:mah] synonym: "peroxisome degradation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "pexophagy abolished" EXACT [PomBase:mah] synonym: "pexophagy: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000380 ! abolished autophagy created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000526 name: decreased peroxisome degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of pexophagy is decreased." [PomBase:mah] synonym: "decreased peroxisome degradation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pexophagy" EXACT [PomBase:mah] synonym: "pexophagy: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced peroxisome degradation" EXACT [PomBase:mah] is_a: FYPO:0000381 ! decreased autophagy is_a: FYPO:0000811 ! abnormal peroxisome organization created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000527 name: decreased rate of peroxisome degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of pexophagy is decreased." [PomBase:mah] synonym: "decreased rate of peroxisome degradation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of pexophagy" EXACT [PomBase:mah] synonym: "pexophagy: decreased rate" EXACT [SGD:phenotype_annotation] synonym: "reduced rate of peroxisome degradation" EXACT [PomBase:mah] is_a: FYPO:0000382 ! decreased rate of autophagy is_a: FYPO:0000811 ! abnormal peroxisome organization created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000528 name: delayed peroxisome degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which pexophagy is delayed." [PomBase:mah] synonym: "delayed peroxisome degradation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed pexophagy" EXACT [PomBase:mah] synonym: "pexophagy: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000383 ! delayed autophagy is_a: FYPO:0000811 ! abnormal peroxisome organization created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000529 name: normal peroxisome degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisome degradation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal peroxisome degradation during vegetative growth" EXACT [PomBase:mah] synonym: "normal pexophagy" EXACT [PomBase:mah] synonym: "pexophagy: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000385 ! normal autophagy created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000530 name: abnormal cell cycle arrest in response to pheromone def: "A cellular process phenotype in which the cell cycle arrest that normally occurs in response to pheromone is abnormal." [PomBase:mah] synonym: "abnormal pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000302 ! abnormal response to pheromone is_a: FYPO:0001026 ! abnormal occurrence of normal cell cycle arrest created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000531 name: abolished cell cycle arrest in response to pheromone def: "A cellular process phenotype in which cell cycle arrest in response to pheromone does not occur." [PomBase:mah] synonym: "absent pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "cell cycle arrest in response to pheromone abolished" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest abolished" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000530 ! abnormal cell cycle arrest in response to pheromone created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000532 name: decreased cell cycle arrest in response to pheromone def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to pheromone is decreased." [PomBase:mah] synonym: "decreased pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced cell cycle arrest in response to pheromone" EXACT [PomBase:mah] is_a: FYPO:0000530 ! abnormal cell cycle arrest in response to pheromone created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000533 name: normal cell cycle arrest in response to pheromone def: "A cellular process phenotype in which cell cycle arrest in response to pheromone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "pheromone-induced cell cycle arrest: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001025 ! normally arrested cell cycle progression created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000534 name: abnormal spindle pole body localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body localization is abnormal." [PomBase:mah] synonym: "abnormal position of spindle pole body" EXACT [PomBase:mah] synonym: "abnormal SPB localization" EXACT [PomBase:mah] synonym: "abnormal spindle pole body localisation" EXACT [PomBase:mah] synonym: "abnormal spindle pole body localization during vegetative growth" EXACT [PomBase:mah] synonym: "position of spindle pole body: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000535 name: normal spindle pole body localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body localization is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal position of spindle pole body" EXACT [PomBase:mah] synonym: "normal SPB localization" EXACT [PomBase:mah] synonym: "normal spindle pole body localisation" EXACT [PomBase:mah] synonym: "normal spindle pole body localization during vegetative growth" EXACT [PomBase:mah] synonym: "position of spindle pole body: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000536 name: abnormal protein secretion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion is abnormal." [PomBase:mah] synonym: "abnormal protein secretion during vegetative growth" EXACT [PomBase:mah] synonym: "protein secretion: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000540 ! abnormal protein transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000537 name: abolished protein secretion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion does not occur." [PomBase:mah] synonym: "absent protein secretion" EXACT [PomBase:mah] synonym: "protein secretion abolished" EXACT [PomBase:mah] synonym: "protein secretion abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein secretion: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000536 ! abnormal protein secretion created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000538 name: decreased protein secretion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein secretion is decreased." [PomBase:mah] synonym: "decreased protein secretion during vegetative growth" EXACT [PomBase:mah] synonym: "protein secretion: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced protein secretion" EXACT [PomBase:mah] is_a: FYPO:0000536 ! abnormal protein secretion is_a: FYPO:0000541 ! decreased protein transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000539 name: increased protein secretion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein secretion is increased." [PomBase:mah] synonym: "increased protein secretion during vegetative growth" EXACT [PomBase:mah] synonym: "protein secretion: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000536 ! abnormal protein secretion created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000540 name: abnormal protein transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport is abnormal." [PomBase:mah] synonym: "abnormal protein transport during vegetative growth" EXACT [PomBase:mah] synonym: "protein transport: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000541 name: decreased protein transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein transport is decreased." [PomBase:mah] synonym: "decreased protein transport during vegetative growth" EXACT [PomBase:mah] synonym: "protein transport: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced protein transport" EXACT [PomBase:mah] is_a: FYPO:0000540 ! abnormal protein transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000542 name: increased rate of protein transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of protein transport is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased rate of protein transport during vegetative growth" EXACT [PomBase:mah] synonym: "protein transport: increased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000540 ! abnormal protein transport created_by: midori creation_date: 2011-08-15T11:08:30Z [Term] id: FYPO:0000544 name: abolished protein modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification does not occur. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] synonym: "abolished protein/peptide modification" EXACT [PomBase:mah] synonym: "absent protein/peptide modification" EXACT [PomBase:mah] synonym: "protein modification abolished" EXACT [PomBase:mah] synonym: "protein modification abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein/peptide modification: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000329 ! abnormal protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000545 name: decreased protein modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein modification is decreased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] synonym: "decreased protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced protein modification" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000546 name: delayed protein modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is delayed. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] synonym: "delayed protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "delayed protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000329 ! abnormal protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000547 name: increased protein modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein modification is increased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] synonym: "increased protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000329 ! abnormal protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000548 name: increased duration of protein modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein modification processes is increased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins." [PomBase:mah] synonym: "increased duration of protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: increased duration" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000329 ! abnormal protein modification created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000549 name: normal protein modification def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal protein modification during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein/peptide modification" EXACT [PomBase:mah] synonym: "protein/peptide modification: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000859 ! normal metabolic process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000550 name: abnormal pseudohyphal growth alt_id: FYPO:0000435 def: "A cellular process phenotype in which pseudohyphal growth is abnormal." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abnormal filamentous growth" BROAD [PomBase:mah] synonym: "filamentous growth: abnormal" BROAD [SGD:phenotype_annotation] synonym: "pseudohyphal growth: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000045 ! abnormal cell population growth is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000551 name: pseudohyphal growth abolished alt_id: FYPO:0000436 def: "A cellular process phenotype in which pseudohyphal growth does not occur." [PomBase:mah] synonym: "abolished filamentous growth" BROAD [PomBase:mah] synonym: "abolished pseudohyphal growth" EXACT [PomBase:mah] synonym: "absent filamentous growth" BROAD [PomBase:mah] synonym: "absent pseudohyphal growth" EXACT [PomBase:mah] synonym: "filamentous growth abolished" BROAD [PomBase:mah] synonym: "filamentous growth: absent" BROAD [SGD:phenotype_annotation] synonym: "pseudohyphal growth: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000550 ! abnormal pseudohyphal growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000552 name: decreased pseudohyphal growth alt_id: FYPO:0000437 def: "A cellular process phenotype in which the occurrence of pseudohyphal growth is decreased." [PomBase:mah] synonym: "decreased filamentous growth" BROAD [PomBase:mah] synonym: "filamentous growth: decreased" BROAD [SGD:phenotype_annotation] synonym: "pseudohyphal growth: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced pseudohyphal growth" EXACT [PomBase:mah] is_a: FYPO:0000550 ! abnormal pseudohyphal growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000553 name: increased pseudohyphal growth during cellular hyperosmotic response alt_id: FYPO:0000438 def: "A cellular process phenotype in which the occurrence of pseudohyphal growth is increased during a cellular hyperosmotic response." [PomBase:mah] synonym: "increased filamentous growth during cellular hyperosmotic response" BROAD [PomBase:mah] is_a: FYPO:0000550 ! abnormal pseudohyphal growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000554 name: normal pseudohyphal growth alt_id: FYPO:0000439 def: "A cell population phenotype in which pseudohyphal growth is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "filamentous growth: normal" BROAD [SGD:phenotype_annotation] synonym: "normal filamentous growth" BROAD [PomBase:mah] synonym: "pseudohyphal growth: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000047 ! normal cell population growth is_a: FYPO:0002062 ! normal cell growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000555 name: abnormal re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest is abnormal." [PomBase:mah] synonym: "abnormal recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000302 ! abnormal response to pheromone created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000556 name: abolished re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest does not occur." [PomBase:mah] synonym: "absent recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "re-entry into mitotic cell cycle after pheromone arrest abolished" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest abolished" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000557 name: decreased re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle after pheromone arrest is decreased." [PomBase:mah] synonym: "decreased recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced re-entry into mitotic cell cycle after pheromone arrest" EXACT [PomBase:mah] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000558 name: increased re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle after pheromone arrest is increased." [PomBase:mah] synonym: "increased recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000559 name: increased rate of re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which the rate of re-entry into the mitotic cell cycle after pheromone arrest is increased." [PomBase:mah] synonym: "increased rate of recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: increased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000555 ! abnormal re-entry into mitotic cell cycle after pheromone arrest created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000560 name: normal re-entry into mitotic cell cycle after pheromone arrest def: "A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal recovery from pheromone-induced cell cycle arrest" EXACT [PomBase:mah] synonym: "recovery from pheromone-induced cell cycle arrest: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0001113 ! normal cellular response to pheromone created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000561 name: normal mitotic G1 phase progression def: "A cellular process phenotype in which progression through the G1 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: normal" EXACT [SGD:phenotype_annotation] synonym: "normal mitotic cell cycle progression in G1" EXACT [PomBase:mah] synonym: "normal mitotic G1 phase progression during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000411 ! normal cell cycle progression created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000562 name: abolished cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration does not occur." [PomBase:mah] synonym: "absent respiratory metabolism" EXACT [PomBase:mah] synonym: "cellular respiration abolished" EXACT [PomBase:mah] synonym: "cellular respiration abolished during vegetative growth" EXACT [PomBase:mah] synonym: "respiration abolished" BROAD [PomBase:mah] synonym: "respiratory metabolism abolished" EXACT [PomBase:mah] synonym: "respiratory metabolism: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000563 name: abnormal mitotic G2 phase progression def: "A cellular process phenotype in which progression through the G2 phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in G2" EXACT [PomBase:mah] synonym: "abnormal mitotic G2 phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G2 phase: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000564 name: decreased rate of cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of cellular respiration is decreased." [PomBase:mah] synonym: "decreased rate of cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of respiration" BROAD [PomBase:mah] synonym: "decreased rate of respiratory metabolism" EXACT [PomBase:mah] synonym: "reduced rate of cellular respiration" EXACT [PomBase:mah] synonym: "respiratory metabolism: decreased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000565 name: increased cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular respiration is increased." [PomBase:mah] synonym: "increased cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "increased respiration" BROAD [PomBase:mah] synonym: "increased respiratory metabolism" EXACT [PomBase:mah] synonym: "respiratory metabolism: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000078 ! abnormal cellular respiration created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000566 name: normal cellular respiration def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular respiration during vegetative growth" EXACT [PomBase:mah] synonym: "normal respiration" BROAD [PomBase:mah] synonym: "normal respiratory metabolism" EXACT [PomBase:mah] synonym: "respiratory metabolism: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000859 ! normal metabolic process created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000567 name: decreased duration of septation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septation is decreased." [PomBase:mah] synonym: "decreased barrier septum formation involved in cell cycle cytokinesis" RELATED [PomBase:mah] synonym: "decreased duration of barrier septum formation involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "decreased duration of septation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased septation" RELATED [PomBase:mah] synonym: "decreased septum formation" RELATED [PomBase:mah] synonym: "reduced duration of septation" EXACT [PomBase:mah] synonym: "septum formation: decreased" BROAD [SGD:phenotype_annotation] is_a: FYPO:0000117 ! abnormal septation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000568 name: abnormal shmoo formation def: "A cellular process phenotype in which mating projection assembly is abnormal." [PomBase:mah] synonym: "abnormal conjugation tube formation" EXACT [PomBase:mah] synonym: "abnormal mating projection assembly" EXACT [PomBase:mah] synonym: "abnormal mating projection formation" EXACT [PomBase:mah] synonym: "abnormal shmoo assembly" EXACT [PomBase:mah] synonym: "shmoo formation: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000569 name: abolished shmoo formation def: "A cellular process phenotype in which mating projection assembly does not occur." [PomBase:mah] synonym: "abolished conjugation tube formation" EXACT [PomBase:mah] synonym: "absent shmoo formation" EXACT [PomBase:mah] synonym: "mating projection assembly abolished" EXACT [PomBase:mah] synonym: "mating projection formation abolished" EXACT [PomBase:mah] synonym: "shmoo assembly abolished" EXACT [PomBase:mah] synonym: "shmoo formation abolished" EXACT [PomBase:mah] synonym: "shmoo formation: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000570 name: decreased shmoo formation def: "A cellular process phenotype in which the occurrence of mating projection assembly is decreased." [PomBase:mah] synonym: "decreased conjugation tube formation" EXACT [PomBase:mah] synonym: "decreased mating projection assembly" EXACT [PomBase:mah] synonym: "decreased mating projection formation" EXACT [PomBase:mah] synonym: "decreased shmoo assembly" EXACT [PomBase:mah] synonym: "reduced shmoo formation" EXACT [PomBase:mah] synonym: "shmoo formation: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000571 name: decreased rate of shmoo formation def: "A cellular process phenotype in which the rate of mating projection assembly is decreased." [PomBase:mah] synonym: "decreased rate of conjugation tube formation" EXACT [PomBase:mah] synonym: "decreased rate of mating projection assembly" EXACT [PomBase:mah] synonym: "decreased rate of mating projection formation" EXACT [PomBase:mah] synonym: "decreased rate of shmoo assembly" EXACT [PomBase:mah] synonym: "reduced rate of shmoo formation" EXACT [PomBase:mah] synonym: "shmoo formation: decreased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000572 name: increased rate of shmoo formation def: "A cellular process phenotype in which the rate of mating projection assembly is increased." [PomBase:mah] synonym: "increased rate of conjugation tube formation" EXACT [PomBase:mah] synonym: "increased rate of mating projection assembly" EXACT [PomBase:mah] synonym: "increased rate of mating projection formation" EXACT [PomBase:mah] synonym: "increased rate of shmoo assembly" EXACT [PomBase:mah] synonym: "shmoo formation: increased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000568 ! abnormal shmoo formation created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000573 name: normal shmoo formation def: "A cellular process phenotype in which mating projection assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal conjugation tube formation" EXACT [PomBase:mah] synonym: "normal mating projection assembly" EXACT [PomBase:mah] synonym: "normal mating projection formation" EXACT [PomBase:mah] synonym: "normal shmoo assembly" EXACT [PomBase:mah] synonym: "shmoo formation: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000574 name: abnormal gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing is abnormal." [PomBase:mah] synonym: "abnormal gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000575 name: abolished gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing does not occur." [PomBase:mah] synonym: "absent silencing" EXACT [PomBase:mah] synonym: "gene silencing abolished" EXACT [PomBase:mah] synonym: "gene silencing abolished during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000574 ! abnormal gene silencing created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000576 name: decreased gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of gene silencing is decreased." [PomBase:mah] synonym: "decreased gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "reduced gene silencing" EXACT [PomBase:mah] synonym: "silencing: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000574 ! abnormal gene silencing created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000577 name: increased gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of gene silencing is increased." [PomBase:mah] synonym: "increased gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000574 ! abnormal gene silencing created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000578 name: normal gene silencing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal gene silencing during vegetative growth" EXACT [PomBase:mah] synonym: "silencing: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000579 name: normal spore germination def: "A cellular process phenotype in which spore germination is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "spore germination: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000580 name: abnormal ascospore wall biogenesis def: "A cellular process phenotype in which ascospore wall biogenesis is abnormal." [PomBase:mah] synonym: "abnormal spore wall formation" RELATED [PomBase:mah] synonym: "spore wall formation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000174 ! abnormal cell wall biogenesis created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000581 name: decreased spore germination def: "A cellular process phenotype in which the occurrence of spore germination is decreased." [PomBase:mah] synonym: "reduced spore germination" EXACT [PomBase:mah] synonym: "spore germination: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000305 ! abnormal spore germination created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000582 name: decreased rate of spore germination def: "A cellular process phenotype in which the rate of spore germination is decreased." [PomBase:mah] synonym: "reduced rate of spore germination" EXACT [PomBase:mah] synonym: "spore germination: decreased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000305 ! abnormal spore germination created_by: midori creation_date: 2011-08-15T11:41:34Z [Term] id: FYPO:0000583 name: abolished sporulation def: "A cellular process phenotype in which ascospore formation does not occur." [PomBase:mah] synonym: "absent sporulation" EXACT [PomBase:mah] synonym: "ascospore formation abolished" EXACT [PomBase:mah] synonym: "sporulation abolished" EXACT [PomBase:mah] synonym: "sporulation: absent" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000584 name: decreased sporulation def: "A cellular process phenotype in which the occurrence of ascospore formation is decreased." [PomBase:mah] synonym: "decreased ascospore formation" EXACT [PomBase:mah] synonym: "decreased sporulation frequency" EXACT [PomBase:mah] synonym: "reduced sporulation" EXACT [PomBase:mah] synonym: "sporulation: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000585 name: abolished ascospore wall biogenesis def: "A cellular process phenotype in which ascospore wall biogenesis does not occur." [PomBase:mah] synonym: "absent spore wall formation" RELATED [PomBase:mah] synonym: "ascospore wall biogenesis abolished" EXACT [PomBase:mah] synonym: "spore wall formation abolished" RELATED [PomBase:mah] synonym: "spore wall formation: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000580 ! abnormal ascospore wall biogenesis created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000586 name: abolished ascospore wall assembly def: "A cellular process phenotype in which ascospore wall assembly does not occur." [PomBase:mah] synonym: "absent spore wall formation" RELATED [PomBase:mah] synonym: "ascospore wall assembly abolished" EXACT [PomBase:mah] synonym: "spore wall formation abolished" RELATED [PomBase:mah] synonym: "spore wall formation: absent" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000175 ! abnormal ascospore wall assembly created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000587 name: delayed sporulation def: "A cellular process phenotype in which ascospore formation is delayed." [PomBase:mah] synonym: "delayed ascospore formation" EXACT [PomBase:mah] synonym: "sporulation: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000588 name: increased sporulation def: "A cellular process phenotype in which the occurrence of ascospore formation is increased." [PomBase:mah] synonym: "increased ascospore formation" EXACT [PomBase:mah] synonym: "sporulation: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000589 name: increased rate of sporulation def: "A cellular process phenotype in which the rate of ascospore formation is increased, i.e. sporulation takes place more rapidly than in wild type." [PomBase:mah] synonym: "increased rate of ascospore formation" EXACT [PomBase:mah] synonym: "sporulation: increased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000590 name: normal sporulation def: "A cellular process phenotype in which ascospore formation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal ascospore formation" EXACT [PomBase:mah] synonym: "sporulation: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0000679 ! developmental process phenotype created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000591 name: abnormal transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition is abnormal." [PomBase:mah] synonym: "abnormal transposable element transposition" EXACT [PomBase:mah] synonym: "abnormal transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000592 name: abolished transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition does not occur." [PomBase:mah] synonym: "absent transposable element transposition" EXACT [PomBase:mah] synonym: "transposable element transposition abolished" EXACT [PomBase:mah] synonym: "transposable element transposition: absent" EXACT [SGD:phenotype_annotation] synonym: "transposition abolished" EXACT [PomBase:mah] synonym: "transposition abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000593 name: decreased transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of transposition is decreased." [PomBase:mah] synonym: "decreased transposable element transposition" EXACT [PomBase:mah] synonym: "decreased transposition during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transposition" EXACT [PomBase:mah] synonym: "transposable element transposition: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000594 name: increased transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of transposition is increased." [PomBase:mah] synonym: "increased transposable element transposition" EXACT [PomBase:mah] synonym: "increased transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000595 name: increased rate of transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of transposition is increased." [PomBase:mah] synonym: "increased rate of transposable element transposition" EXACT [PomBase:mah] synonym: "increased rate of transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: increased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000591 ! abnormal transposition created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000596 name: normal transposition def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal transposable element transposition" EXACT [PomBase:mah] synonym: "normal transposition during vegetative growth" EXACT [PomBase:mah] synonym: "transposable element transposition: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000597 name: abnormal vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport is abnormal." [PomBase:mah] synonym: "abnormal vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "vacuolar transport: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000598 name: decreased vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of vacuolar transport is decreased." [PomBase:mah] synonym: "decreased vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "reduced vacuolar transport" EXACT [PomBase:mah] synonym: "vacuolar transport: decreased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000464 ! decreased intracellular transport is_a: FYPO:0000597 ! abnormal vacuolar transport created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000599 name: decreased rate of vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of vacuolar transport is decreased." [PomBase:mah] synonym: "decreased rate of vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "reduced rate of vacuolar transport" EXACT [PomBase:mah] synonym: "vacuolar transport: decreased rate" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000597 ! abnormal vacuolar transport created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000600 name: delayed vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport is delayed." [PomBase:mah] synonym: "delayed vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "vacuolar transport: delayed" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000597 ! abnormal vacuolar transport created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000601 name: normal vacuolar transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal vacuolar transport during vegetative growth" EXACT [PomBase:mah] synonym: "vacuolar transport: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000602 name: abnormal mitotic G1 phase progression def: "A cellular process phenotype in which progression through the G1 phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in G1" EXACT [PomBase:mah] synonym: "abnormal mitotic G1 phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000603 name: decreased duration of mitotic G1 phase def: "A cellular process phenotype in which the duration of G1 phase of a mitotic cell cycle is shorter than normal." [PomBase:mah] synonym: "decreased duration of mitotic G1 phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in G1 phase: decreased duration" EXACT [SGD:phenotype_annotation] synonym: "reduced duration of mitotic G1 phase" EXACT [PomBase:mah] is_a: FYPO:0000602 ! abnormal mitotic G1 phase progression is_a: FYPO:0001070 ! decreased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-15T12:00:20Z [Term] id: FYPO:0000607 name: abnormal mitotic M phase progression def: "A cellular process phenotype in which progression through M phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in M" EXACT [PomBase:mah] synonym: "abnormal mitotic M phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in M phase: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000608 name: mitotic cell cycle arrest in M phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in M phase." [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in M phase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in M phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in M phase: arrested" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle is_a: FYPO:0000607 ! abnormal mitotic M phase progression created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000610 name: abnormal mitotic S phase progression def: "A cellular process phenotype in which progression through S phase of the mitotic cell cycle is abnormal." [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in S" EXACT [PomBase:mah] synonym: "abnormal mitotic S phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in S phase: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000611 name: mitotic cell cycle arrest in S phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in S phase." [PomBase:mah] comment: Cells arrested in S phase typically have more than 1C, but less than 2C, DNA content. synonym: "abnormal mitotic cell cycle arrest in S phase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in S phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in S phase: arrested" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000610 ! abnormal mitotic S phase progression is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000614 name: increased duration of mitotic S phase alt_id: FYPO:0000612 alt_id: FYPO:0000613 def: "A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is longer than normal." [PomBase:mah] synonym: "decreased rate of mitotic S phase progression" RELATED [PomBase:mah] synonym: "delayed mitotic S phase progression" RELATED [PomBase:mah] synonym: "delayed mitotic S phase progression during vegetative growth" RELATED [PomBase:mah] synonym: "increased duration of mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in S phase: decreased rate" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in S phase: delayed" EXACT [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in S phase: increased duration" EXACT [SGD:phenotype_annotation] synonym: "reduced rate of mitotic S phase progression" RELATED [PomBase:mah] is_a: FYPO:0000610 ! abnormal mitotic S phase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000615 name: decreased duration of mitotic S phase def: "A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is shorter than normal." [PomBase:mah] synonym: "decreased duration of mitotic S phase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in S phase: increased rate" RELATED [SGD:phenotype_annotation] synonym: "reduced duration of mitotic S phase" EXACT [PomBase:mah] is_a: FYPO:0000610 ! abnormal mitotic S phase progression is_a: FYPO:0001070 ! decreased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000616 name: abnormal mitotic anaphase progression def: "A cellular process phenotype in which progression through mitotic anaphase is abnormal." [PomBase:mah] synonym: "abnormal mitotic anaphase progression during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic cell cycle progression in anaphase" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in anaphase: abnormal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000607 ! abnormal mitotic M phase progression created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000618 name: increased duration of mitotic anaphase alt_id: FYPO:0000617 def: "A cellular process phenotype in which the duration of progression through the anaphase of mitosis is longer than normal." [PomBase:mah] synonym: "delayed mitotic anaphase progression" RELATED [PomBase:mah] synonym: "increased duration of mitotic anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of mitotic anaphase progression" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in anaphase: delayed" RELATED [SGD:phenotype_annotation] synonym: "mitotic cell cycle progression in anaphase: increased duration" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000616 ! abnormal mitotic anaphase progression is_a: FYPO:0001069 ! increased duration of mitotic cell cycle phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000619 name: mitotic cell cycle arrest in anaphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in anaphase." [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in anaphase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in anaphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in late anaphase: arrested" NARROW [SGD:phenotype_annotation] is_a: FYPO:0000608 ! mitotic cell cycle arrest in M phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000620 name: mitotic cell cycle arrest in metaphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in metaphase." [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in metaphase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in metaphase: arrested" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000608 ! mitotic cell cycle arrest in M phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000621 name: delayed onset of mitotic metaphase def: "A cellular process phenotype in which the onset of metaphase of mitosis is delayed." [PomBase:mah] synonym: "delayed mitotic metaphase" EXACT [PomBase:mah] synonym: "delayed onset of mitotic metaphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in metaphase: delayed" EXACT [SGD:phenotype_annotation] synonym: "mitotic metaphase delay" EXACT [PomBase:mah] is_a: FYPO:0000409 ! delayed cell cycle phase transition created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000622 name: mitotic cell cycle arrest in telophase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in telophase." [PomBase:mah] synonym: "abnormal mitotic cell cycle arrest in telophase" EXACT [PomBase:mah] synonym: "mitotic cell cycle arrest in telophase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle progression in telophase: arrested" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000608 ! mitotic cell cycle arrest in M phase created_by: midori creation_date: 2011-08-16T10:03:01Z [Term] id: FYPO:0000623 name: abnormal positive regulation of transcription def: "A transcription regulation phenotype in which any process of positive regulation of transcription is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. There may be enough evidence to support annotation to a more specific term such as 'abnormal transcriptional response to pheromone' (FYPO:0000984); if not, it is safer to annotate to 'increased transcription' (FYPO:0000780) or 'decreased transcription' (FYPO:0000781) rather than explicitly claiming that an effect on regulation was observed. subset: qc_do_not_annotate synonym: "abnormal activation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal activation of transcription, DNA-dependent" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of cellular transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal positive regulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal stimulation of gene-specific transcription" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal stimulation of transcription, DNA-dependent" NARROW [GO:0045893, PomBase:mah] synonym: "abnormal up regulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal up regulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal up-regulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal up-regulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] synonym: "abnormal upregulation of gene-specific transcription" RELATED [GO:0045893, PomBase:mah] synonym: "abnormal upregulation of transcription, DNA-dependent" EXACT [GO:0045893, PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-19T03:38:05Z [Term] id: FYPO:0000624 name: abnormal negative regulation of transcription def: "A transcription regulation phenotype in which any process of negative regulation of transcription is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. There may be enough evidence to support annotation to a more specific term such as 'abnormal chromatin silencing' (FYPO:0000144); if not, it is safer to annotate to 'increased transcription' (FYPO:0000780) or 'decreased transcription' (FYPO:0000781) rather than explicitly claiming that an effect on regulation was observed. subset: qc_do_not_annotate synonym: "abnormal down regulation of gene-specific transcription" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal down regulation of transcription, DNA-dependent" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal down-regulation of gene-specific transcription" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal down-regulation of transcription, DNA-dependent" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal downregulation of gene-specific transcription" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal downregulation of transcription, DNA-dependent" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal inhibition of gene-specific transcription" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal inhibition of transcription, DNA-dependent" NARROW [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of cellular transcription, DNA-dependent" EXACT [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of gene-specific transcription" RELATED [GO:0045892, PomBase:mah] synonym: "abnormal negative regulation of transcription during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal negative regulation of transcription, DNA-dependent" EXACT [GO:0045892, PomBase:mah] is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-19T03:40:47Z [Term] id: FYPO:0000625 name: abnormal premeiotic DNA replication def: "A cellular process phenotype in which premeiotic DNA replication is abnormal." [PomBase:mah] synonym: "abnormal meiotic DNA replication" RELATED [GO:0006279, GOC:mah] synonym: "abnormal meiotic DNA synthesis" RELATED [GO:0006279, GOC:mah] synonym: "abnormal premeiotic DNA synthesis" RELATED [GO:0006279, GOC:mah] is_a: FYPO:0000217 ! abnormal DNA replication created_by: midori creation_date: 2011-08-19T03:48:13Z [Term] id: FYPO:0000626 name: abnormal initiation of premeiotic DNA replication def: "A cellular process phenotype in which the initiation of premeiotic DNA replication is abnormal." [PomBase:mah] synonym: "abnormal initiation of meiotic DNA synthesis" RELATED [GO:0072691, GOC:mah] synonym: "abnormal initiation of premeiotic DNA synthesis" RELATED [GO:0072691, GOC:mah] synonym: "abnormal meiotic DNA replication initiation" RELATED [GO:0072691, GOC:mah] synonym: "abnormal premeiotic DNA replication initiation" EXACT [GO:0072691, GOC:mah] is_a: FYPO:0000176 ! abnormal DNA replication initiation is_a: FYPO:0000625 ! abnormal premeiotic DNA replication created_by: midori creation_date: 2011-08-19T03:49:02Z [Term] id: FYPO:0000627 name: normal cellular process def: "A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000114 ! cellular process phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2011-08-19T04:05:16Z [Term] id: FYPO:0000628 name: abnormal cellular process def: "A phenotype in which a specific cellular process is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000114 ! cellular process phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-08-19T04:06:34Z [Term] id: FYPO:0000629 name: abnormal apoptosis def: "A cellular process phenotype in which apoptosis is abnormal. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies." [GO:0006915, PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-19T04:10:09Z [Term] id: FYPO:0000630 name: abnormal biofilm formation def: "A cellular process phenotype in which biofilm formation is abnormal." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2011-08-19T04:12:58Z [Term] id: FYPO:0000631 name: cell cycle phenotype def: "A cellular process phenotype that affects progression of the mitotic or meiotic cell cycle, or regulation of cell cycle progression." [PomBase:mah] synonym: "cell-division cycle phenotype" EXACT [GO:0007049, PomBase:mah] synonym: "fission yeast cell cycle phenotype" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype created_by: midori creation_date: 2011-08-19T04:16:04Z [Term] id: FYPO:0000632 name: mitochondrial translation phenotype def: "A cellular process phenotype that affects mitochondrial translation." [PomBase:mah] synonym: "fission yeast mitochondrial translation phenotype" EXACT [PomBase:mah] synonym: "mitochondrial translation phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000291 ! translation phenotype created_by: midori creation_date: 2011-08-23T04:58:17Z [Term] id: FYPO:0000633 name: sensitive to G418 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to G418. Cells stop growing (and may die) at a concentration of G418 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to G418" EXACT [PomBase:mah] synonym: "sensitive to G418 during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to Geneticin" EXACT [CHEBI:459363, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-08-23T04:58:25Z [Term] id: FYPO:0000634 name: protein localization to centromere abolished def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to centromere" EXACT [PomBase:mah] synonym: "protein absent from centromere" RELATED [PomBase:mah] synonym: "protein localisation to centromere abolished" EXACT [PomBase:mah] synonym: "protein localisation to chromosome, centromeric region, abolished" EXACT [GO:0071459, PomBase:mah] synonym: "protein localization to centromere abolished during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to chromosome, centric region, abolished" EXACT [GO:0071459, PomBase:mah] synonym: "protein localization to chromosome, centromeric region, abolished" EXACT [GO:0071459, PomBase:mah] is_a: FYPO:0001179 ! protein localization abolished during vegetative growth created_by: midori creation_date: 2011-08-23T04:58:31Z [Term] id: FYPO:0000635 name: growth auxotrophic for leucine def: "Auxotrophy in which leucine is required for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for leucine during vegetative growth" EXACT [PomBase:mah] synonym: "leucine auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2011-08-23T05:17:07Z [Term] id: FYPO:0000636 name: increased cell population growth rate def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced cell population growth" RELATED [PomBase:mah] synonym: "fast cell population growth" EXACT [PomBase:mah] synonym: "increased cell population growth rate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001356 ! abnormal vegetative cell population growth created_by: midori creation_date: 2011-08-31T01:30:12Z [Term] id: FYPO:0000637 name: increased cell population growth rate on glucose carbon source def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing glucose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced growth on glucose" RELATED [PomBase:mah] synonym: "fast cell population growth on glucose carbon source" EXACT [PomBase:mah] synonym: "increased vegetative cell population growth rate on glucose carbon source" EXACT [PomBase:mah] is_a: FYPO:0000636 ! increased cell population growth rate is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-08-31T02:20:29Z [Term] id: FYPO:0000639 name: delayed septation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation takes place later than normal." [PomBase:al, PomBase:mah] synonym: "delayed barrier septum formation involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "delayed septation during vegetative growth" EXACT [PomBase:mah] synonym: "delayed septum formation" BROAD [PomBase:mah] is_a: FYPO:0000117 ! abnormal septation is_a: FYPO:0000420 ! delayed cytokinesis created_by: midori creation_date: 2011-08-31T02:55:54Z [Term] id: FYPO:0000640 name: abnormal chromatin silencing at centromere central core def: "A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the central core of the centromeric regions is abnormal." [PomBase:mah] comment: Note that the centromere central core corresponds to SO:0001796. synonym: "abnormal centromere central core chromatin silencing" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromere central core during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal chromatin silencing at centromeric central core" EXACT [PomBase:mah] synonym: "abnormal heterochromatic silencing at centromere central core" EXACT [PomBase:mah] is_a: FYPO:0000146 ! abnormal chromatin silencing at centromere created_by: midori creation_date: 2011-09-12T03:33:40Z [Term] id: FYPO:0000641 name: abnormal chromosome organization def: "A cellular process phenotype in which any process of chromosome organization is abnormal. Chromosome organization results in the assembly, arrangement of constituent parts, or disassembly of chromosomes." [GO:0051276, PomBase:mah] comment: Consider annotating to 'abnormal chromosome morphology' (FYPO:0000848), but note that an abnormal chromosome organization process may, but does not necessarily, result in abnormal chromosome morphology. synonym: "abnormal chromosome organisation" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2011-09-28T12:10:13Z [Term] id: FYPO:0000642 name: abnormal chromatin organization def: "A cellular process phenotype in which any process of chromatin organization is abnormal. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal chromatin organisation" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2011-09-28T12:16:57Z [Term] id: FYPO:0000643 name: abnormal DNA integrity checkpoint def: "A cell cycle checkpoint phenotype in which a DNA integrity checkpoint is abnormal. A DNA integrity checkpoint normally regulates cell cycle progression in response to changes in DNA structure. In a mutant, the checkpoint may fail to activate under appropriate conditions, or may occur to a greater or lesser extent than wild type under any specified set of conditions." [PomBase:mah] synonym: "abnormal DNA integrity checkpoint activation" EXACT [PomBase:mah] is_a: FYPO:0001704 ! abnormal cell cycle checkpoint created_by: midori creation_date: 2011-09-28T12:28:26Z [Term] id: FYPO:0000644 name: normal protein localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular protein localization is normal." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal cellular protein localization" EXACT [PomBase:mah] synonym: "normal protein localisation" EXACT [PomBase:mah] synonym: "normal protein localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2011-10-05T04:52:48Z [Term] id: FYPO:0000645 name: small vegetative cell def: "A cell morphology phenotype in which a vegetative cell has an abnormally low volume." [PomBase:mah] is_a: FYPO:0000023 ! small cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2011-10-07T02:03:07Z [Term] id: FYPO:0000646 name: swollen vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell has a larger volume than normal." [PomBase:mah] is_a: FYPO:0000025 ! swollen cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2011-10-07T04:19:54Z [Term] id: FYPO:0000647 name: cell lysis def: "An inviable phenotype in which a vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised." [PomBase:mah] synonym: "cell lysis during vegetative growth" EXACT [PomBase:mah] synonym: "cytolysis" EXACT [PomBase:mah] synonym: "inviable, lysed cell" EXACT [PomBase:mah] is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth relationship: has_part FYPO:0000049 ! inviable cell created_by: midori creation_date: 2011-10-10T03:28:02Z [Term] id: FYPO:0000648 name: small viable vegetative cell def: "A cell morphology phenotype in which a vegetatively growing cell is viable but has an abnormally low volume. Note that small viable cells result from a cell cycle size regulation defect." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "small viable cell during vegetative growth" EXACT [PomBase:mah] synonym: "wee" EXACT [PomBase:jh, PomBase:mah] is_a: FYPO:0000645 ! small vegetative cell is_a: FYPO:0001491 ! viable vegetative cell relationship: has_part FYPO:0000023 ! small cell relationship: has_part FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2011-10-13T12:06:45Z [Term] id: FYPO:0000650 name: increased septation index def: "A cell population phenotype in which the septation index is higher than normal. The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for wild type." [PomBase:mah, PomBase:vw] synonym: "increased septation" RELATED [PomBase:mah] synonym: "septated" RELATED [PomBase:vw] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype relationship: includes_cells_with_phenotype FYPO:0000651 ! increased duration of septation created_by: midori creation_date: 2011-10-13T12:34:42Z [Term] id: FYPO:0000651 name: increased duration of septation alt_id: FYPO:0000649 def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septation is increased." [PomBase:mah] synonym: "increased barrier septum formation involved in cell cycle cytokinesis" RELATED [PomBase:mah] synonym: "increased duration of barrier septum formation involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "increased duration of septation during vegetative growth" EXACT [PomBase:mah] synonym: "increased duration of septum formation" BROAD [PomBase:mah] synonym: "increased septation" RELATED [PomBase:mah] synonym: "increased septum formation" RELATED [PomBase:mah] is_a: FYPO:0000117 ! abnormal septation created_by: midori creation_date: 2011-10-13T03:07:53Z [Term] id: FYPO:0000652 name: molecular function phenotype def: "A phenotype that affects a molecular function such as binding or catalytic activity." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast molecular function phenotype" EXACT [PomBase:mah] synonym: "molecular function phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000001 ! phenotype created_by: midori creation_date: 2011-11-11T10:42:36Z [Term] id: FYPO:0000653 name: DNA binding phenotype def: "A phenotype that affects DNA binding." [PomBase:mah] synonym: "fission yeast DNA binding phenotype" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2011-11-11T10:43:39Z [Term] id: FYPO:0000654 name: catalytic activity phenotype def: "A phenotype that affects a catalytic activity." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "enzymatic activity phenotype" EXACT [PomBase:mah] synonym: "fission yeast catalytic activity phenotype" EXACT [PomBase:mah] is_a: FYPO:0000652 ! molecular function phenotype created_by: midori creation_date: 2011-11-11T10:44:09Z [Term] id: FYPO:0000655 name: normal DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a mutated gene product is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000653 ! DNA binding phenotype is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000656 name: abnormal DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is abnormal, when the gene product or the bound DNA sequence is mutated." [PomBase:mah] is_a: FYPO:0000653 ! DNA binding phenotype is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000657 name: increased DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is increased, when the gene product or the bound DNA sequence is mutated." [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000658 name: decreased DNA binding def: "A molecular function phenotype in which occurrence of DNA binding by a gene product is decreased, when the gene product or the bound DNA sequence is mutated." [PomBase:mah] synonym: "reduced DNA binding" EXACT [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000659 name: abolished DNA binding def: "A molecular function phenotype in which DNA binding by a gene product does not occur, when the gene product or the bound DNA sequence is mutated." [PomBase:mah] synonym: "DNA binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000656 ! abnormal DNA binding created_by: midori creation_date: 2011-11-11T10:45:30Z [Term] id: FYPO:0000660 name: normal catalytic activity def: "A molecular function phenotype in which a the observed rate of a specified catalytic activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000654 ! catalytic activity phenotype is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000661 name: abnormal catalytic activity def: "A molecular function phenotype in which a the observed rate of a specified catalytic activity is abnormal." [PomBase:mah] is_a: FYPO:0000654 ! catalytic activity phenotype is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000662 name: increased catalytic activity def: "A molecular function phenotype in which a the observed rate of a specified catalytic activity is increased." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000663 name: decreased catalytic activity def: "A molecular function phenotype in which a the observed rate of a specified catalytic activity is decreased." [PomBase:mah] synonym: "reduced catalytic activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000664 name: abolished catalytic activity def: "A molecular function phenotype in which a specified catalytic activity is absent." [PomBase:mah] synonym: "catalytic activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:28Z [Term] id: FYPO:0000665 name: normal peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal protease activity" EXACT [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000666 name: abnormal peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is abnormal." [PomBase:mah] synonym: "abnormal protease activity" EXACT [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000667 name: increased peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is increased." [PomBase:mah] synonym: "increased protease activity" EXACT [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000666 ! abnormal peptidase activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000668 name: decreased peptidase activity def: "A molecular function phenotype in which the observed rate of a peptidase activity is decreased." [PomBase:mah] synonym: "decreased protease activity" EXACT [PomBase:mah] synonym: "reduced peptidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000666 ! abnormal peptidase activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000669 name: abolished peptidase activity def: "A molecular function phenotype in which a peptidase activity is absent." [PomBase:mah] synonym: "abolished protease activity" EXACT [PomBase:mah] synonym: "peptidase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000666 ! abnormal peptidase activity created_by: midori creation_date: 2011-11-11T10:46:47Z [Term] id: FYPO:0000670 name: abnormal mitotic chromosome separation def: "A cellular process phenotype in which mitotic chromosome separation is abnormal." [PomBase:mah] synonym: "abnormal chromosome separation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal mitotic sister chromatid separation" EXACT [GO:0051306] synonym: "aneuploidy" RELATED [PomBase:vw] synonym: "mitotic chromosome nondisjunction" EXACT [PomBase:mah] is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth relationship: part_of FYPO:0000141 ! abnormal mitotic sister chromatid segregation created_by: midori creation_date: 2011-11-11T01:51:59Z [Term] id: FYPO:0000671 name: abnormal rDNA separation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome separation at the rDNA repeat regions is abnormal." [PomBase:mah] synonym: "abnormal rDNA separation during mitosis" EXACT [PomBase:mah] synonym: "abnormal rDNA separation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal segregation of nucleolar rDNA" RELATED [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic chromosome separation created_by: midori creation_date: 2011-11-11T01:59:59Z [Term] id: FYPO:0000672 name: normal cell morphology def: "A cell phenotype characterized by normal cell morphology." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "cellular morphology: normal" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000136 ! cellular structure phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2011-11-11T02:51:12Z [Term] id: FYPO:0000673 name: normal septation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal septation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2011-11-11T02:53:07Z [Term] id: FYPO:0000674 name: normal cell population growth at high temperature def: "A cell population growth phenotype in which vegetative cells grow normally at a high temperature." [PomBase:mah] synonym: "heat sensitivity: normal" RELATED [SGD:phenotype_annotation] synonym: "normal growth at high temperature" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth at high temperature" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth is_a: FYPO:0002060 ! viable vegetative cell population relationship: includes_cells_with_phenotype FYPO:0000282 ! viable cell at high temperature created_by: midori creation_date: 2011-11-11T02:55:04Z [Term] id: FYPO:0000675 name: abnormal protein targeting def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which protein targeting is abnormal." [PomBase:mah] comment: Encompasses both targeting of proteins to a particular location where they are not normally found and decreased or no targeting of proteins normally found in the location. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein targeting during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000215 ! abnormal intracellular protein transport created_by: midori creation_date: 2011-11-11T03:24:12Z [Term] id: FYPO:0000676 name: abnormal protein targeting to vacuole def: "A transport phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole is abnormal." [PomBase:mah] comment: Encompasses both targeting of proteins to the vacuole where they are not normally found and decreased or no targeting of proteins normally found in the vacuole. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein targeting to vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vacuolar protein sorting" EXACT [PomBase:mah] is_a: FYPO:0000597 ! abnormal vacuolar transport is_a: FYPO:0000675 ! abnormal protein targeting created_by: midori creation_date: 2011-11-11T03:25:01Z [Term] id: FYPO:0000677 name: abnormal protein targeting to prospore membrane def: "A transport phenotype in which protein targeting to the prospore membrane is abnormal." [PomBase:mah] comment: Encompasses both targeting of proteins to the prospore membrane where they are not normally found and decreased or no targeting of proteins normally found in the prospore membrane. We recommend noting which protein(s) were used in the assay when annotating to this term. is_a: FYPO:0000675 ! abnormal protein targeting created_by: midori creation_date: 2011-11-29T05:16:27Z [Term] id: FYPO:0000678 name: chromosome nondisjunction at meiosis I def: "A cellular process phenotype in which homologous chromosomes fail to segregate properly, or disjoin, during meiosis I." [PomBase:mah] is_a: FYPO:0000925 ! unequal meiotic chromosome segregation created_by: midori creation_date: 2011-11-29T05:44:25Z [Term] id: FYPO:0000679 name: developmental process phenotype def: "A phenotype that affects a developmental process." [PomBase:mah] synonym: "fission yeast developmental process phenotype" EXACT [PomBase:mah] is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2011-11-29T06:02:16Z [Term] id: FYPO:0000680 name: abnormal ascus development def: "A developmental process phenotype in which ascus development is abnormal." [PomBase:mah] is_a: FYPO:0000679 ! developmental process phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-11-29T06:03:31Z [Term] id: FYPO:0000681 name: abnormal sporulation resulting in formation of two-spore ascus def: "A sporulation phenotype that results in the formation of an ascus that has abnormal morphology and contains two diploid spores." [PMID:11156975, PomBase:mah, PomBase:vw] synonym: "abnormal ascospore formation resulting in formation of two-spore ascus" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of two-spore asci" EXACT [PomBase:mah] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2011-12-01T01:29:02Z [Term] id: FYPO:0000682 name: abnormal regulation of molecular function def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a molecular function is abnormal." [PomBase:mah] synonym: "abnormal regulation of molecular function during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-12-01T01:43:05Z [Term] id: FYPO:0000683 name: constitutive catalytic activity def: "A regulation phenotype in which the basal activity of an enzyme is increased relative to normal. Basal enzyme activity is the activity observed in the absence of a regulator. Abnormally elevated basal activity may or may not reach the levels observed in the normal activated state." [PomBase:al, PomBase:mah] synonym: "constitutive catalytic activity during vegetative growth" EXACT [PomBase:mah] synonym: "constitutive enzymatic activity" EXACT [PomBase:mah] synonym: "constitutively active enzyme" RELATED [PomBase:mah] is_a: FYPO:0000682 ! abnormal regulation of molecular function created_by: midori creation_date: 2011-12-01T01:51:53Z [Term] id: FYPO:0000684 name: decreased cell population growth on glycerol carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol as the carbon source." [PomBase:al, PomBase:mah] comment: Note that trace amounts of another carbon source are usually required for S. pombe growth on glycerol; yeast extract-based rich medium supplies the trace substance, but minimal medium must be supplemented. It is therefore important to annotate the growth medium as an experimental condition when using this term. Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on glycerol carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on glycerol carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on glycerol carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on glycerol carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-12-01T04:41:03Z [Term] id: FYPO:0000685 name: transcriptional response to pheromone at decreased pheromone level def: "A cellular response phenotype in which pheromone-responsive positive regulation of transcription occurs at a lower level of pheromone than normal." [PomBase:mah] synonym: "increased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "increased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "sensitive to pheromone" RELATED [PomBase:al, PomBase:mah] is_a: FYPO:0000623 ! abnormal positive regulation of transcription is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2011-12-01T04:46:17Z [Term] id: FYPO:0000686 name: normal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity def: "A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000687 name: abnormal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity def: "A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000688 name: decreased peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity def: "A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is decreased." [PomBase:mah] synonym: "reduced peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000687 ! abnormal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000689 name: abnormal oxidoreductase activity def: "A molecular function phenotype in which the observed rate of an oxidoreductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000690 name: decreased oxidoreductase activity def: "A molecular function phenotype in which the observed rate of an oxidoreductase activity is decreased." [PomBase:mah] synonym: "reduced oxidoreductase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000691 name: normal DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000692 name: abnormal DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000693 name: decreased DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is decreased." [PomBase:mah] synonym: "reduced DNA-1,N6-ethenoadenine N-glycosylase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000692 ! abnormal DNA-1,N6-ethenoadenine N-glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000694 name: abolished DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which DNA-1,N6-ethenoadenine N-glycosylase activity is absent." [PomBase:mah] synonym: "DNA-1,N6-ethenoadenine N-glycosylase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000692 ! abnormal DNA-1,N6-ethenoadenine N-glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000695 name: increased DNA-1,N6-ethenoadenine N-glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000692 ! abnormal DNA-1,N6-ethenoadenine N-glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000696 name: normal DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000697 name: abnormal DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000698 name: decreased DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is decreased." [PomBase:mah] synonym: "reduced DNA-7-methylguanine glycosylase activity" EXACT [PomBase:al] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000697 ! abnormal DNA-7-methylguanine glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000699 name: abolished DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which DNA-7-methylguanine glycosylase activity is absent." [PomBase:mah] synonym: "DNA-7-methylguanine glycosylase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000697 ! abnormal DNA-7-methylguanine glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000700 name: increased DNA-7-methylguanine glycosylase activity def: "A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000697 ! abnormal DNA-7-methylguanine glycosylase activity created_by: midori creation_date: 2011-12-01T05:15:00Z [Term] id: FYPO:0000701 name: abolished DNA damage checkpoint override in response to caffeine def: "A cellular response phenotype in which caffeine does not override the DNA damage checkpoint (as it does in wild type cells), allowing mitotic cell cycle arrest to occur." [PMID:10224243, PomBase:mah] synonym: "caffeine-mediated DNA damage checkpoint override abolished" EXACT [GOC:mah, GOC:vw] synonym: "DNA damage checkpoint override in response to caffeine abolished" EXACT [PomBase:mah] synonym: "DNA damage checkpoint override in response to caffeine abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000207 ! abnormal cellular response to caffeine is_a: FYPO:0001704 ! abnormal cell cycle checkpoint created_by: midori creation_date: 2011-12-05T01:59:12Z [Term] id: FYPO:0000702 name: protein binding phenotype def: "A phenotype that protein affects the binding of one protein to another." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast protein binding phenotype" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2011-12-05T02:24:49Z [Term] id: FYPO:0000703 name: normal protein binding def: "A molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is tested in a mutant, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "normal protein-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0000702 ! protein binding phenotype is_a: FYPO:0000706 ! normal molecular function created_by: midori creation_date: 2011-12-05T02:25:15Z [Term] id: FYPO:0000704 name: abnormal protein binding def: "A molecular function phenotype in which the binding of one protein to another is abnormal." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abnormal protein-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0000702 ! protein binding phenotype is_a: FYPO:0000707 ! abnormal molecular function created_by: midori creation_date: 2011-12-05T02:25:58Z [Term] id: FYPO:0000705 name: abolished protein binding def: "A molecular function phenotype in which the binding of one protein to another does not occur." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "abolished protein-protein interaction" EXACT [PomBase:mah] synonym: "protein binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein binding created_by: midori creation_date: 2011-12-05T02:26:17Z [Term] id: FYPO:0000706 name: normal molecular function def: "A phenotype in which a specific molecular function is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0000652 ! molecular function phenotype created_by: midori creation_date: 2011-12-05T03:06:23Z [Term] id: FYPO:0000707 name: abnormal molecular function def: "A phenotype in which a specific molecular function is abnormal." [PomBase:mah] is_a: FYPO:0000652 ! molecular function phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2011-12-05T03:09:24Z [Term] id: FYPO:0000708 name: decreased mating efficiency def: "A biological process phenotype in which the observed mating efficiency is lower than normal." [PMID:15300681, PMID:16598689, PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). synonym: "mating efficiency: decreased" EXACT [SGD:phenotype_annotation] synonym: "reduced mating efficiency" EXACT [PomBase:mah] is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2011-12-05T04:26:20Z [Term] id: FYPO:0000709 name: decreased cell population growth during nitrogen starvation def: "A cell growth phenotype in which cell population growth is decreased relative to normal under nitrogen starvation conditions, such as in nitrogen-deficient minimal medium." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased cell population growth in response to nitrogen starvation" EXACT [PomBase:mah] synonym: "reduced cell population growth during nitrogen starvation" RELATED [PomBase:mah] synonym: "slow cell population growth during nitrogen starvation" NARROW [PomBase:mah] synonym: "slow cell population growth in nitrogen-deficient minimal medium" RELATED [PomBase:al, PomBase:mah] synonym: "slow growth during nitrogen starvation" BROAD [PomBase:mah] is_a: FYPO:0000046 ! decreased cell population growth is_a: FYPO:0000152 ! abnormal cellular response to nitrogen starvation created_by: midori creation_date: 2011-12-05T04:43:53Z [Term] id: FYPO:0000710 name: abnormal cell cycle arrest in response to nitrogen starvation def: "A cellular process phenotype in which cell cycle arrest in response to nitrogen starvation, which normally occurs in G1 phase, is abnormal." [PomBase:mah] is_a: FYPO:0000152 ! abnormal cellular response to nitrogen starvation is_a: FYPO:0001026 ! abnormal occurrence of normal cell cycle arrest created_by: midori creation_date: 2011-12-06T12:15:03Z [Term] id: FYPO:0000711 name: decreased cell cycle arrest in response to nitrogen starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation is decreased." [PomBase:mah] synonym: "reduced cell cycle arrest in response to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000710 ! abnormal cell cycle arrest in response to nitrogen starvation created_by: midori creation_date: 2011-12-06T12:15:32Z [Term] id: FYPO:0000712 name: delayed cell cycle arrest in response to nitrogen starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation is delayed." [PomBase:mah] is_a: FYPO:0000710 ! abnormal cell cycle arrest in response to nitrogen starvation created_by: midori creation_date: 2011-12-06T12:16:53Z [Term] id: FYPO:0000713 name: abnormal cellular response to starvation def: "A stress response phenotype in which the response to starvation for one or more nutrients is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000162 ! abnormal cellular response to stress created_by: midori creation_date: 2011-12-06T12:25:40Z [Term] id: FYPO:0000714 name: sensitive to leptomycin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to leptomycin B. Cells stop growing (and may die) at a concentration of leptomycin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to leptomycin B" EXACT [PomBase:mah] synonym: "sensitive to leptomycin B during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to LMB" EXACT [CHEBI:52646, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000715 name: sensitive to K-252a def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to K-252a. Cells stop growing (and may die) at a concentration of K-252a that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to K-252a" EXACT [PomBase:mah] synonym: "sensitive to K-252a during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000716 name: sensitive to valinomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to valinomycin. Cells stop growing (and may die) at a concentration of valinomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to valinomycin" EXACT [PomBase:mah] synonym: "sensitive to valinomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000717 name: sensitive to actinomycin D def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to actinomycin D. Cells stop growing (and may die) at a concentration of actinomycin D that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to actinomycin D" EXACT [PomBase:mah] synonym: "sensitive to actinomycin D during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000718 name: sensitive to trisodium vanadate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trisodium vanadate (also known as sodium orthovanadate). Cells stop growing (and may die) at a concentration of trisodium vanadate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to trisodium vanadate" EXACT [PomBase:mah] synonym: "sensitive to sodium orthovanadate" EXACT [CHEBI:35607, PomBase:al] synonym: "sensitive to trisodium vanadate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2011-12-06T12:31:38Z [Term] id: FYPO:0000719 name: normal fatty acid synthase activity def: "A molecular function phenotype in which the observed rate of fatty acid synthase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal FAS activity" EXACT [PomBase:al, PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2011-12-06T01:43:30Z [Term] id: FYPO:0000720 name: abnormal fatty acid synthase activity def: "A molecular function phenotype in which the observed rate of fatty acid synthase activity is abnormal." [PomBase:mah] synonym: "abnormal FAS activity" EXACT [PomBase:al, PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2011-12-06T01:57:58Z [Term] id: FYPO:0000721 name: abnormal cellular response to pH def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a pH stimulus is abnormal." [PomBase:mah] synonym: "abnormal cellular response to pH during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2011-12-06T02:45:18Z [Term] id: FYPO:0000722 name: sensitive to acidity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acidic pH. Cells stop growing (and may die) at a pH that allows wild type cells to grow." [PomBase:mah] comment: In chemistry, acid pH is below 7.0. This term, however, is most useful for annotating phenotypes observed at any pH lower than that of standard fission yeast media, about 5.8. Also see 'sensitive to low pH' (FYPO:0001989). synonym: "acid pH resistance: decreased" EXACT [SGD:phenotype_annotation] synonym: "hypersensitive to acidity" EXACT [PomBase:mah] synonym: "sensitive to acidity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000721 ! abnormal cellular response to pH created_by: midori creation_date: 2011-12-06T02:47:00Z [Term] id: FYPO:0000723 name: sensitive to alkalinity def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to alkaline pH. Cells stop growing (and may die) at a pH that allows wild type cells to grow." [PomBase:mah] comment: In chemistry, alkaline pH is over 7.0. This term, however, is most useful for annotating phenotypes observed at any pH higher than that of standard fission yeast media, about 5.8. Also see 'sensitive to high pH' (FYPO:0001987). synonym: "alkaline pH resistance: decreased" EXACT [SGD:phenotype_annotation] synonym: "hypersensitive to alkalinity" EXACT [PomBase:mah] synonym: "sensitive to alkalinity during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000721 ! abnormal cellular response to pH created_by: midori creation_date: 2011-12-06T02:48:18Z [Term] id: FYPO:0000724 name: resistance to N-methyl-N'-nitro-N-nitrosoguanidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N-methyl-N'-nitro-N-nitrosoguanidine than normal." [PomBase:mah] synonym: "resistance to methylnitronitrosoguanidine" EXACT [CHEBI:21759] synonym: "resistance to N-methyl-N'-nitro-N-nitrosoguanidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to MNNG" EXACT [CHEBI:21759] synonym: "resistant to N-methyl-N'-nitro-N-nitrosoguanidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-12-06T04:17:30Z [Term] id: FYPO:0000725 name: resistance to methyl methanesulfonate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methyl methanesulfonate than normal." [PomBase:mah] synonym: "resistance to methyl methanesulfonate during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to methyl methanesulphonate" EXACT [PomBase:mah] synonym: "resistance to MMS" EXACT [PomBase:mah] synonym: "resistant to methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2011-12-07T11:28:32Z [Term] id: FYPO:0000726 name: sensitive to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to oxidative stress." [PomBase:mah] synonym: "hypersensitive to oxidative stress" EXACT [PomBase:mah] synonym: "oxidative stress resistance: decreased" EXACT [SGD:phenotype_annotation] synonym: "sensitive to oxidative stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress is_a: FYPO:0001340 ! abnormal cellular response to oxidative stress during vegetative growth created_by: midori creation_date: 2011-12-07T01:17:37Z [Term] id: FYPO:0000727 name: abnormal actin filament organization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of cytoskeletal structures comprising actin filaments does not occur normally." [GO:0007015, PomBase:mah] synonym: "abnormal actin filament organisation" EXACT [PomBase:mah] synonym: "abnormal actin filament organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization created_by: midori creation_date: 2011-12-07T02:53:31Z [Term] id: FYPO:0000728 name: abnormal actin cortical patch assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch assembly is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000790 ! abnormal actin cortical patch organization created_by: midori creation_date: 2011-12-07T03:02:33Z [Term] id: FYPO:0000729 name: delayed actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly is delayed." [PomBase:mah] synonym: "delayed actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "delayed actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:vw] synonym: "delayed contractile ring assembly" EXACT [PomBase:mah] synonym: "delayed cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "delayed cytokinetic ring formation" RELATED [PomBase:vw] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly is_a: FYPO:0000420 ! delayed cytokinesis created_by: midori creation_date: 2011-12-07T04:50:03Z [Term] id: FYPO:0000730 name: long spindle def: "A spindle phenotype in which the spindle is longer than normal." [PomBase:mah] synonym: "long spindles" EXACT [PomBase:mah] is_a: FYPO:0000120 ! abnormal spindle created_by: midori creation_date: 2011-12-07T04:51:57Z [Term] id: FYPO:0000731 name: abnormal protein localization to medial cortex during vegetative growth def: "A cell phenotype in which the localization of a protein to the medial cortex is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to medial cortex during vegetative growth" EXACT [GO:0071574, PomBase:mah] synonym: "abnormal protein localization to medial ring during vegetative growth" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0000928 ! abnormal protein localization to cell cortex is_a: FYPO:0001373 ! abnormal protein localization to medial cortex created_by: midori creation_date: 2011-12-07T05:16:57Z [Term] id: FYPO:0000732 name: short mitotic spindle def: "A spindle phenotype in which the mitotic spindle is shorter than normal." [PomBase:mah] comment: Note that short mitotic spindles are usually not parallel to the long axis of the cell, because short spindle formation takes place before spindle orientation is established (see GO:0000132). synonym: "short bipolar mitotic spindle" EXACT [PomBase:vw] synonym: "short mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "short mitotic spindles" EXACT [PomBase:mah] is_a: FYPO:0000130 ! short spindle is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle created_by: midori creation_date: 2012-01-11T11:30:01Z [Term] id: FYPO:0000733 name: long mitotic spindle def: "A spindle phenotype in which the mitotic spindle is longer than normal." [PomBase:mah] synonym: "long bipolar mitotic spindle" EXACT [PomBase:vw] synonym: "long mitotic spindle during vegetative growth" EXACT [PomBase:mah] synonym: "long mitotic spindles" EXACT [PomBase:mah] is_a: FYPO:0000730 ! long spindle is_a: FYPO:0001574 ! abnormal bipolar mitotic spindle created_by: midori creation_date: 2012-01-11T11:30:01Z [Term] id: FYPO:0000734 name: abnormal meiotic spindle def: "A cellular structure phenotype in which the structure of the meiotic spindle is abnormal." [PomBase:mah] is_a: FYPO:0000120 ! abnormal spindle created_by: midori creation_date: 2012-01-11T11:30:13Z [Term] id: FYPO:0000735 name: short meiotic spindle def: "A spindle phenotype in which the meiotic spindle is shorter than normal." [PomBase:mah] synonym: "short meiotic spindles" EXACT [PomBase:mah] is_a: FYPO:0000130 ! short spindle is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2012-01-11T11:30:48Z [Term] id: FYPO:0000736 name: long meiotic spindle def: "A spindle phenotype in which the meiotic spindle is longer than normal." [PomBase:mah] synonym: "long meiotic spindles" EXACT [PomBase:mah] is_a: FYPO:0000730 ! long spindle is_a: FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2012-01-11T11:30:48Z [Term] id: FYPO:0000737 name: abnormal meiotic spindle assembly def: "A cellular process phenotype in which assembly of the meiotic spindle is abnormal." [PomBase:mah] synonym: "abnormal spindle assembly involved in meiosis" EXACT [PomBase:mah] is_a: FYPO:0000051 ! abnormal meiosis is_a: FYPO:0000119 ! abnormal spindle assembly relationship: results_in_formation_of FYPO:0000734 ! abnormal meiotic spindle created_by: midori creation_date: 2012-01-11T11:42:55Z [Term] id: FYPO:0000739 name: cellular pigment accumulation phenotype def: "A cellular process phenotype that affects the occurrence of pigment accumulation in a cell." [PomBase:mah] comment: Note that this term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "cellular pigment accumulation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast cellular pigment accumulation phenotype" EXACT [PomBase:mah] is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-01-11T12:21:14Z [Term] id: FYPO:0000740 name: normal cellular pigment accumulation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Note that normal cells do not accumulate detectable levels of any pigment; also note that this term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "normal cellular pigment accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000739 ! cellular pigment accumulation phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-01-11T12:27:26Z [Term] id: FYPO:0000741 name: increased cellular pigment accumulation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased." [PomBase:mah] comment: Note that normal cells do not accumulate detectable levels of any pigment; for this reason, FYPO does not include separate terms for 'increased' and 'abnormal' pigment accumulation. Also note that pigment accumulates in the vacuole. This term refers to GO:0033059 'cellular pigmentation', rather than GO:0043482 'cellular pigment accumulation', because GO:0043482 has paths to 'response to stimulus' in GO. synonym: "abnormal cellular pigment accumulation" EXACT [PomBase:mah] synonym: "altered colony color" RELATED [PomBase:al, PomBase:mah] synonym: "altered colony colour" RELATED [PomBase:al, PomBase:mah] synonym: "increased cellular pigment accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000739 ! cellular pigment accumulation phenotype is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-01-11T12:29:34Z [Term] id: FYPO:0000742 name: abnormal protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found in actin cortical patches and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to actin cortical patch" EXACT [PomBase:mah] synonym: "abnormal protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-01-11T12:45:30Z [Term] id: FYPO:0000743 name: abnormal actin cortical patch internalization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch internalisation" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch internalization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal actin patch internalization" EXACT [PomBase:vw] is_a: FYPO:0000190 ! abnormal actin cortical patch localization is_a: FYPO:0000790 ! abnormal actin cortical patch organization created_by: midori creation_date: 2012-01-11T12:50:31Z [Term] id: FYPO:0000744 name: normal protein localization to actin cortical patch def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to actin cortical patch" EXACT [PomBase:mah] synonym: "normal protein localization to actin cortical patch during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization created_by: midori creation_date: 2012-01-11T01:47:11Z [Term] id: FYPO:0000745 name: delayed actin cortical patch internalization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization is delayed." [PomBase:mah] synonym: "delayed abnormal actin cortical patch internalization during vegetative growth" EXACT [PomBase:mah] synonym: "delayed actin cortical patch internalisation" EXACT [PomBase:mah] is_a: FYPO:0000743 ! abnormal actin cortical patch internalization created_by: midori creation_date: 2012-01-11T01:57:25Z [Term] id: FYPO:0000746 name: abolished actin cortical patch internalization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization does not occur." [PomBase:mah] synonym: "abolished actin cortical patch internalisation" EXACT [PomBase:mah] synonym: "abolished actin cortical patch internalization during vegetative growth" EXACT [PomBase:mah] synonym: "actin cortical patch internalization abolished" EXACT [PomBase:mah] is_a: FYPO:0000743 ! abnormal actin cortical patch internalization created_by: midori creation_date: 2012-01-11T01:57:40Z [Term] id: FYPO:0000747 name: growth auxotrophic for adenine def: "Auxotrophy in which adenine is required for vegetative cell growth." [PomBase:mah] synonym: "adenine auxotrophy" EXACT [PomBase:mah] synonym: "growth auxotrophic for adenine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2012-01-11T01:59:50Z [Term] id: FYPO:0000748 name: sensitive to mercury def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mercury ions. Cells stop growing (and may die) at a concentration of mercury ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mercury" EXACT [PomBase:mah] synonym: "sensitive to mercury during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to mercury ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-11T02:03:34Z [Term] id: FYPO:0000749 name: sensitive to selenite ion def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to selenite ((SeO3)2-) ions. Cells stop growing (and may die) at a concentration of selenite ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to selenite ion" EXACT [PomBase:mah] synonym: "sensitive to selenite ion during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to selenite ions" EXACT [PomBase:mah] synonym: "sensitive to selenium" RELATED [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-11T02:09:20Z [Term] id: FYPO:0000750 name: sensitive to silver def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to silver ions. Cells stop growing (and may die) at a concentration of silver ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to silver" EXACT [PomBase:mah] synonym: "sensitive to silver during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to silver ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-11T02:23:17Z [Term] id: FYPO:0000751 name: sensitive to nickel def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nickel ions. Cells stop growing (and may die) at a concentration of nickel ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nickel" EXACT [PomBase:mah] synonym: "sensitive to nickel during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to nickel ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-11T02:23:37Z [Term] id: FYPO:0000752 name: resistance to selenate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of selenate ions than normal." [PomBase:mah] synonym: "resistance to selenate during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to selenate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-01-11T02:24:43Z [Term] id: FYPO:0000753 name: normal glutathione gamma-glutamylcysteinyltransferase activity def: "A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-01-11T02:33:09Z [Term] id: FYPO:0000754 name: abnormal glutathione gamma-glutamylcysteinyltransferase activity def: "A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-01-11T02:34:18Z [Term] id: FYPO:0000755 name: decreased glutathione gamma-glutamylcysteinyltransferase activity def: "A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is decreased." [PomBase:mah] synonym: "reduced glutathione gamma-glutamylcysteinyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000754 ! abnormal glutathione gamma-glutamylcysteinyltransferase activity created_by: midori creation_date: 2012-01-11T02:34:31Z [Term] id: FYPO:0000756 name: sensitive to bafilomycin A1 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bafilomycin A1. Cells stop growing (and may die) at a concentration of bafilomycin A1 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bafilomycin A1" EXACT [PomBase:mah] synonym: "sensitive to bafilomycin A" RELATED [PomBase:mah] synonym: "sensitive to bafilomycin A1 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-12T11:24:11Z [Term] id: FYPO:0000757 name: sensitive to nigericin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nigericin. Cells stop growing (and may die) at a concentration of nigericin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to nigericin" EXACT [PomBase:mah] synonym: "sensitive to nigericin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-12T11:25:08Z [Term] id: FYPO:0000758 name: sensitive to bismuth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bismuth. Cells stop growing (and may die) at a concentration of bismuth that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to bismuth" EXACT [PomBase:mah] synonym: "sensitive to bismuth during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-18T03:00:13Z [Term] id: FYPO:0000759 name: sensitive to lead def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to lead ions. Cells stop growing (and may die) at a concentration of lead ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to lead" EXACT [PomBase:mah] synonym: "sensitive to lead during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to lead ions" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-01-18T03:00:32Z [Term] id: FYPO:0000760 name: normal conjugation def: "A cellular process phenotype in which conjugation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal conjugation frequency" NARROW [PomBase:mah] synonym: "normal conjugation with cellular fusion" EXACT [PomBase:mah] synonym: "normal zygote formation" RELATED [PomBase:mah] is_a: FYPO:0000301 ! mating phenotype is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2012-01-18T03:02:59Z [Term] id: FYPO:0000761 name: increased conjugation frequency def: "A conjugation phenotype in which conjugation occurs more frequently than normal." [PomBase:mah] comment: Note that this term refers specifically to conjugation, whereas experiments that measure mating efficiency often do so by counting zygotes plus asci, sometimes also including spores. For such experiments, we recommend using 'increased mating efficiency' (FYPO:0001043). synonym: "increased conjugation efficiency" EXACT [PomBase:mah] synonym: "increased occurrence of conjugation" EXACT [PomBase:mah] synonym: "increased zygote formation" RELATED [PomBase:mah] is_a: FYPO:0000031 ! abnormal conjugation created_by: midori creation_date: 2012-01-18T03:03:19Z [Term] id: FYPO:0000762 name: protein accumulation def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which specific proteins abnormally accumulate in the cell, or in a part of the cell such as within an organelle." [PomBase:mah] synonym: "protein accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-02-09T02:50:56Z [Term] id: FYPO:0000763 name: resistance to cadmium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cadmium ions than normal." [PomBase:mah] synonym: "resistance to cadmium during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000764 name: resistance to cycloheximide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of selenate ions than normal." [PomBase:mah] synonym: "resistance to cycloheximide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000765 name: resistance to leptomycin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of leptomycin B than normal." [PomBase:mah] synonym: "resistance to leptomycin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000766 name: resistance to N-ethylmaleimide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of selenate ions than normal." [PomBase:mah] synonym: "resistance to N-ethylmaleimide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000767 name: resistance to staurosporine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of selenate ions than normal." [PomBase:mah] synonym: "resistance to staurosporine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000768 name: resistance to valinomycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of selenate ions than normal." [PomBase:mah] synonym: "resistance to valinomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-02-09T03:40:24Z [Term] id: FYPO:0000769 name: abnormal nuclear envelope morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of all or part of the nuclear envelope is abnormal." [PomBase:mah] comment: Note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "abnormal nuclear envelope morphology during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nuclear membrane morphology" NARROW [PomBase:mah] is_a: FYPO:0000062 ! abnormal nuclear morphology is_a: FYPO:0000353 ! abnormal endomembrane system morphology relationship: output_of FYPO:0000815 ! abnormal nuclear envelope organization created_by: midori creation_date: 2012-02-09T03:51:02Z [Term] id: FYPO:0000770 name: branched nuclear inner membrane def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the nuclear inner membrane forms branched structures that extend into the nuclear lumen." [PMID:21880100, PomBase:mah] synonym: "branched nuclear inner membrane during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology created_by: midori creation_date: 2012-02-09T03:54:48Z [Term] id: FYPO:0000771 name: normal nuclear pore distribution def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which the spatial arrangement of nuclear pores within the nuclear envelope is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal nuclear pore distribution during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization created_by: midori creation_date: 2012-02-09T04:03:08Z [Term] id: FYPO:0000772 name: perforated nuclear envelope def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has perforations or gaps (other than nuclear pores) instead of a continuous structure." [PMID:22156749, PomBase:mah] synonym: "disrupted nuclear envelope" RELATED [PomBase:mah] synonym: "disrupted nuclear membrane" RELATED [PomBase:mah] synonym: "gapped nuclear envelope" EXACT [PomBase:mah] synonym: "perforated nuclear envelope during vegetative growth" EXACT [PomBase:mah] synonym: "perforated nuclear membrane" RELATED [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology created_by: midori creation_date: 2012-02-09T04:12:08Z [Term] id: FYPO:0000773 name: abnormal pre-replicative complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which pre-replicative complex assembly is abnormal." [PomBase:mah] synonym: "abnormal pre-RC assembly" EXACT [PomBase:mah] synonym: "abnormal pre-replicative complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal pre-replicative complex formation" EXACT [GO:0006267, PomBase:mah] is_a: FYPO:0000447 ! abnormal protein complex assembly created_by: midori creation_date: 2012-02-09T04:18:40Z [Term] id: FYPO:0000774 name: decreased pre-replicative complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of pre-replicative complex assembly is decreased." [PomBase:mah] synonym: "decreased pre-RC assembly" EXACT [PomBase:mah] synonym: "decreased pre-replicative complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "decreased pre-replicative complex formation" EXACT [GO:0006267, PomBase:mah] synonym: "reduced pre-replicative complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000773 ! abnormal pre-replicative complex assembly created_by: midori creation_date: 2012-02-09T04:26:56Z [Term] id: FYPO:0000775 name: abnormal protein phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is abnormal." [PomBase:mah] comment: When using this term, it is recommended to note the specific protein(s) affected. synonym: "abnormal protein phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification created_by: midori creation_date: 2012-02-09T04:32:41Z [Term] id: FYPO:0000776 name: normal protein phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: When using this term, it is recommended to note the specific protein(s) affected. synonym: "normal protein phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification created_by: midori creation_date: 2012-02-09T04:33:28Z [Term] id: FYPO:0000777 name: abnormal double-strand break repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair is abnormal." [PomBase:mah] synonym: "abnormal double-strand break repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000188 ! abnormal DNA repair created_by: midori creation_date: 2012-02-09T04:35:48Z [Term] id: FYPO:0000778 name: delayed double-strand break repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair is delayed." [PomBase:mah] synonym: "delayed double-strand break repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000777 ! abnormal double-strand break repair created_by: midori creation_date: 2012-02-09T04:37:10Z [Term] id: FYPO:0000779 name: dumbbell-shaped cell alt_id: FYPO:0000018 def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer than normal and shaped in the form of a dumbbell, i.e. having two connected, rounded parts of approximately equal size, tapering towards a narrower region in the center of the long axis. In some dumbbell-shaped cells, the diameter at the ends is much greater than in wild-type cells." [PomBase:mah] comment: Note that all dumbbell-shaped cells observed are also elongated. The distinction between this phenotype and swollen elongated cells (FYPO:0001429) is that dumbbell-shaped cells have a constriction along the long axis, whereas swollen elongated cells do not. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cell morphology, elongated dumbbell" EXACT [PomBase:mah] synonym: "cell morphology, long dumbbell" EXACT [PomBase:vw] synonym: "dumbbell-shaped cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated dumbbell morphology" EXACT [PomBase:mah] synonym: "elongated inviable dumbbell-shaped cell" EXACT [PomBase:vw] is_a: FYPO:0000950 ! elongated aseptate cell relationship: has_part FYPO:0000017 ! elongated cell created_by: midori creation_date: 2012-02-13T12:48:01Z [Term] id: FYPO:0000780 name: increased transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'increased RNA level' (FYPO:0000825). synonym: "increased transcription during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth relationship: has_output FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-02-28T03:56:27Z [Term] id: FYPO:0000781 name: decreased transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal. All genes, or a specific subset of genes, may be affected." [PomBase:mah] comment: Use this term if there is evidence, such as labeled nucleotide incorporation, showing that transcription rather than RNA stability is affected; otherwise, use 'decreased RNA level' (FYPO:0000826). synonym: "decreased transcription during vegetative growth" EXACT [PomBase:mah] synonym: "reduced transcription" EXACT [PomBase:mah] is_a: FYPO:0000290 ! transcription phenotype is_a: FYPO:0001335 ! transcription regulation phenotype during vegetative growth relationship: has_output FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2012-02-28T03:57:44Z [Term] id: FYPO:0000782 name: mislocalized protein def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is observed in a particular location where it is not normally found." [PomBase:mah] comment: The difference between this term and 'abnormal protein localization' (FYPO:0000443) is that 'mislocalized protein' describes a protein that is observed in a place where it is not normally found, whereas 'abnormal protein localization' additionally encompasses the absence of protein from a place where it is normally found. FYPO:0000782 can therefore be used in any case where a protein is in a different location in a mutant compared to wild type, whereas additional information is usually required to support annotation to FYPO:0000443 or its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "mislocalised protein" EXACT [PomBase:mah] synonym: "mislocalized protein during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype relationship: output_of FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-02-29T12:48:27Z [Term] id: FYPO:0000783 name: protein mislocalized to cytoplasm def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the cytoplasm in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein mislocalised to cytoplasm" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein created_by: midori creation_date: 2012-02-29T12:49:47Z [Term] id: FYPO:0000784 name: protein mislocalized to nucleus alt_id: FYPO:0001251 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nucleus is observed there." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the nucleus in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein mislocalised to nucleus" EXACT [PomBase:mah] synonym: "protein mislocalised to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000782 ! mislocalized protein relationship: output_of FYPO:0001129 ! abnormal protein localization to nucleus created_by: midori creation_date: 2012-02-29T12:50:40Z [Term] id: FYPO:0000785 name: sensitive to formamide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to formamide. Cells stop growing (and may die) at a concentration of formamide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to formamide" EXACT [PomBase:mah] synonym: "sensitive to formamide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-02-29T01:30:18Z [Term] id: FYPO:0000786 name: increased plasmid loss def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which plasmids are lost at a higher frequency than normal. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation." [PomBase:mah] comment: Note that in budding yeast, increased plasmid loss is often called a minichromosome maintenance defect, because "minichromosome" is roughly synonymous with an autonomously replicated and segregated plasmid in that organism. synonym: "increased plasmid loss during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-02-29T01:39:20Z [Term] id: FYPO:0000787 name: abnormal histone H3-K9 trimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 trimethylation" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation created_by: midori creation_date: 2012-02-29T01:43:54Z [Term] id: FYPO:0000788 name: abnormal histone H3-K14 acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K14 acetylation" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0000456 ! abnormal histone acetylation created_by: midori creation_date: 2012-02-29T01:46:18Z [Term] id: FYPO:0000789 name: sensitive to 1-NA-PP1 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1-NA-PP1. Cells stop growing (and may die) at a concentration of 1-NA-PP1 that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 1-NA-PP1" EXACT [PomBase:mah] synonym: "sensitive to 1-NA-PP1 during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to 1-tert-butyl-3-naphthalen-1-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine " EXACT [CHEBI:52310, PomBase:mah] synonym: "sensitive to 4-amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine " EXACT [CHEBI:52310, PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-02-29T01:53:55Z [Term] id: FYPO:0000790 name: abnormal actin cortical patch organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch." [GO:0044396, PomBase:mah] synonym: "abnormal actin cortical patch organisation" EXACT [PomBase:mah] synonym: "abnormal actin cortical patch organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000801 ! abnormal actin cytoskeleton organization is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2012-02-29T03:11:58Z [Term] id: FYPO:0000791 name: abnormal actin cortical patch morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of actin cortical patches is abnormal." [PomBase:mah] synonym: "abnormal actin cortical patch morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology relationship: output_of FYPO:0000790 ! abnormal actin cortical patch organization created_by: midori creation_date: 2012-02-29T03:14:15Z [Term] id: FYPO:0000792 name: normal glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-02-29T03:25:55Z [Term] id: FYPO:0000793 name: abnormal glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is abnormal." [PomBase:mah] is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2012-02-29T03:26:33Z [Term] id: FYPO:0000794 name: abolished glycerol dehydrogenase activity def: "A molecular function phenotype in which glycerol dehydrogenase activity is absent." [PomBase:mah] synonym: "glycerol dehydrogenase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0000793 ! abnormal glycerol dehydrogenase activity created_by: midori creation_date: 2012-02-29T03:27:45Z [Term] id: FYPO:0000795 name: decreased glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is decreased." [PomBase:mah] synonym: "reduced glycerol dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0000690 ! decreased oxidoreductase activity is_a: FYPO:0000793 ! abnormal glycerol dehydrogenase activity created_by: midori creation_date: 2012-02-29T03:27:51Z [Term] id: FYPO:0000796 name: increased glycerol dehydrogenase activity def: "A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is increased." [PomBase:mah] synonym: "increased peptidase activity" EXACT [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000793 ! abnormal glycerol dehydrogenase activity created_by: midori creation_date: 2012-02-29T03:27:58Z [Term] id: FYPO:0000797 name: sensitive to TBPH def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tert-butyl hydroperoxide (TBPH or t-BOOH). Cells stop growing (and may die) at a concentration of TBPH that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to TBPH" EXACT [PomBase:mah] synonym: "sensitive to 2-methyl-prop-2-yl-hydroperoxide" EXACT [CHEBI:64090] synonym: "sensitive to t-BOOH" EXACT [PomBase:al, PomBase:mah] synonym: "sensitive to TBPH during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to tert-butyl hydroperoxide" EXACT [CHEBI:64090, PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-02-29T03:49:47Z [Term] id: FYPO:0000798 name: sensitive to anisomycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to anisomycin. Cells stop growing (and may die) at a concentration of anisomycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to anisomycin" EXACT [PomBase:mah] synonym: "sensitive to anisomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-02-29T03:54:43Z [Term] id: FYPO:0000799 name: sensitive to diamide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide, also known as diamide. Cells stop growing (and may die) at a concentration of diamide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to diamide" EXACT [PomBase:mah] synonym: "sensitive to diamide during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide" EXACT [CHEBI:48958] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-03-01T01:37:57Z [Term] id: FYPO:0000800 name: increased concentration of substance in growth medium def: "A phenotype in which the concentration of a substance released into the growth medium by cells is higher than normal." [PomBase:mah] comment: Note that this term refers only to substances released into the growth medium by cells, not to the concentration of ingredients in the medium as formulated. Consider also annotating to 'increased level of substance in cell' (FYPO:0000990), if there is evidence that the intracellular level of a substance is also increased. synonym: "increased accumulation of substance in growth medium" RELATED [PomBase:mah] synonym: "increased level of substance in growth medium" EXACT [PomBase:mah] synonym: "increased release of substance into growth medium" RELATED [PomBase:mah] is_a: FYPO:0001155 ! altered effect on growth medium created_by: midori creation_date: 2012-03-07T03:41:12Z [Term] id: FYPO:0000801 name: abnormal actin cytoskeleton organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is abnormal." [GO:0030036, PMID:19713940, PomBase:mah] comment: Consider annotating to 'abnormal actin cytoskeleton morphology' (FYPO:0000350), but note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in abnormal actin cytoskeleton morphology. synonym: "abnormal actin cytoskeleton organisation" EXACT [PomBase:mah] synonym: "abnormal actin cytoskeleton organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype is_a: FYPO:0001328 ! abnormal cytoskeleton organization during vegetative growth created_by: midori creation_date: 2012-03-01T02:05:28Z [Term] id: FYPO:0000802 name: abnormal cytoskeleton organization def: "A cellular process phenotype in which cytoskeleton organization is abnormal." [GO:0007010, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cytoskeleton organisation" EXACT [PomBase:mah] is_a: FYPO:0000295 ! cytoskeleton organization phenotype is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2012-03-01T02:43:53Z [Term] id: FYPO:0000803 name: increased concentration of DHA in growth medium def: "A phenotype in which the concentration of glycerone (also called 1,3-dihydroxypropan-2-one, dihydroxyacetone, or DHA) released into the growth medium by cells is higher than normal." [PomBase:mah] synonym: "increased accumulation of DHA in growth medium" RELATED [PomBase:mah] synonym: "increased concentration of 1,3-dihydroxypropan-2-one in growth medium" EXACT [CHEBI:16016] synonym: "increased concentration of dihydroxyacetone in growth medium" EXACT [CHEBI:16016] synonym: "increased concentration of glycerone in growth medium" EXACT [CHEBI:16016] synonym: "increased level of DHA in growth medium" EXACT [PomBase:mah] synonym: "increased release of DHA into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000800 ! increased concentration of substance in growth medium created_by: midori creation_date: 2012-03-07T03:42:46Z [Term] id: FYPO:0000804 name: abnormal endomembrane system organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endomembrane system organization is abnormal. Endomembrane system organization results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system, which encompasses the endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope." [GO:0010256, GO:0012505, PomBase:mah] comment: Consider annotating to 'abnormal endomembrane system morphology' (FYPO:0000353), but note that an abnormal endomembrane system organization process may, but does not necessarily, result in abnormal endomembrane system morphology. synonym: "abnormal endomembrane system organisation" EXACT [PomBase:mah] synonym: "abnormal endomembrane system organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001351 ! abnormal membrane organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:25:09Z [Term] id: FYPO:0000805 name: abnormal endoplasmic reticulum organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endoplasmic reticulum (ER) organization is abnormal. ER organization results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum." [GO:0007029, PomBase:mah] comment: Consider annotating to 'abnormal endoplasmic reticulum morphology' (FYPO:0000354), but note that an abnormal endoplasmic reticulum organization process may, but does not necessarily, result in abnormal endoplasmic reticulum morphology. synonym: "abnormal endoplasmic reticulum organisation" EXACT [PomBase:mah] synonym: "abnormal endoplasmic reticulum organization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal ER organization" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:25:48Z [Term] id: FYPO:0000806 name: abnormal Golgi organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Golgi organization is abnormal. Golgi organization results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GO:0007030, PomBase:mah] comment: Consider annotating to 'abnormal Golgi morphology' (FYPO:0000349), but note that an abnormal Golgi organization process may, but does not necessarily, result in abnormal Golgi morphology. synonym: "abnormal Golgi organisation" EXACT [PomBase:mah] synonym: "abnormal Golgi organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:29:07Z [Term] id: FYPO:0000807 name: abnormal kinetochore organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore organization is abnormal. Kinetochore organization results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, the chromosomal attachment point for the spindle microtubules." [GO:0051383, PomBase:mah] comment: Consider annotating to 'abnormal kinetochore structure' (FYPO:0000050), but note that an abnormal kinetochore organization process may, but does not necessarily, result in abnormal kinetochore structure. synonym: "abnormal kinetochore organisation" EXACT [PomBase:mah] synonym: "abnormal kinetochore organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000641 ! abnormal chromosome organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:29:58Z [Term] id: FYPO:0000808 name: abnormal lipid particle organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lipid particle organization is abnormal. Lipid particle organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle." [GO:0034389, PomBase:mah] comment: Consider annotating to 'abnormal lipid particle morphology' (FYPO:0000356), but note that an abnormal lipid particle organization process may, but does not necessarily, result in abnormal lipid particle morphology. synonym: "abnormal lipid particle organisation" EXACT [PomBase:mah] synonym: "abnormal lipid particle organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:31:02Z [Term] id: FYPO:0000809 name: abnormal mitochondrion organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion organization is abnormal. Mitochondrion organization results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion, and includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome, as well as synthesis of new mitochondrial components." [GO:0007005, PomBase:mah] comment: Consider annotating to 'abnormal mitochondrial morphology' (FYPO:0000359), but note that an abnormal mitochondrion organization process may, but does not necessarily, result in abnormal mitochondrial morphology. synonym: "abnormal mitochondrion organisation" EXACT [PomBase:mah] synonym: "abnormal mitochondrion organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:31:48Z [Term] id: FYPO:0000810 name: abnormal nucleus organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleus organization is abnormal. Nucleus organization results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GO:0006997, PomBase:mah] comment: Consider annotating to 'abnormal nuclear morphology' (FYPO:0000062), but note that an abnormal nucleus organization process may, but does not necessarily, result in abnormal nuclear morphology. synonym: "abnormal nuclear organization" EXACT [PomBase:mah] synonym: "abnormal nucleus organisation" EXACT [PomBase:mah] synonym: "abnormal nucleus organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:34:22Z [Term] id: FYPO:0000811 name: abnormal peroxisome organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisome organization is abnormal. Peroxisome organization results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome." [GO:0007031, PomBase:mah] comment: Consider annotating to 'abnormal peroxisomal morphology' (FYPO:0000362), but note that an abnormal peroxisome organization process may, but does not necessarily, result in abnormal peroxisome morphology. synonym: "abnormal peroxisome organisation" EXACT [PomBase:mah] synonym: "abnormal peroxisome organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:38:04Z [Term] id: FYPO:0000812 name: abnormal vacuole organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole organization is abnormal. Vacuole organization results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GO:0007033, PomBase:mah] comment: Consider annotating to 'abnormal vacuolar morphology' (FYPO:0000368), but note that an abnormal vacuole organization process may, but does not necessarily, result in abnormal vacuolar morphology. synonym: "abnormal vacuolar organisation" EXACT [PomBase:vw] synonym: "abnormal vacuolar organization" EXACT [PomBase:vw] synonym: "abnormal vacuole organisation" EXACT [PomBase:mah] synonym: "abnormal vacuole organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:38:52Z [Term] id: FYPO:0000813 name: abnormal plasma membrane organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which plasma membrane organization is abnormal. Plasma membrane organization results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GO:0007009, PomBase:mah] comment: Consider annotating to 'abnormal plasma membrane morphology' (FYPO:0000364), but note that an abnormal plasma membrane organization process may, but does not necessarily, result in abnormal plasma membrane morphology. synonym: "abnormal plasma membrane organisation" EXACT [PomBase:mah] synonym: "abnormal plasma membrane organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001351 ! abnormal membrane organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:41:39Z [Term] id: FYPO:0000814 name: abnormal nucleolus organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolus organization is abnormal. Nucleolus organization results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [PomBase:mah] comment: Consider annotating to 'abnormal nucleolar morphology' (FYPO:0000361), but note that an abnormal nucleolus organization process may, but does not necessarily, result in abnormal nucleolar morphology. synonym: "abnormal nucleolus organisation" EXACT [PomBase:mah] synonym: "abnormal nucleolus organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000810 ! abnormal nucleus organization created_by: midori creation_date: 2012-03-01T03:42:44Z [Term] id: FYPO:0000815 name: abnormal nuclear envelope organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear envelope organization is abnormal. Nuclear envelope organization results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [PomBase:mah] comment: Consider annotating to 'abnormal nuclear envelope morphology' (FYPO:0000769), but note that an abnormal nuclear envelope organization process may, but does not necessarily, result in abnormal nuclear envelope morphology. synonym: "abnormal nuclear envelope organisation" EXACT [PomBase:mah] synonym: "abnormal nuclear envelope organization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000810 ! abnormal nucleus organization is_a: FYPO:0001351 ! abnormal membrane organization during vegetative growth created_by: midori creation_date: 2012-03-01T03:45:03Z [Term] id: FYPO:0000816 name: decreased concentration of substance in growth medium def: "A phenotype in which the concentration of a substance released into the growth medium by cells is lower than normal." [PomBase:mah] comment: Note that this term refers only to substances released into the growth medium by cells, not to the concentration of ingredients in the medium as formulated. Consider also annotating to 'decreased level of substance in cell' (FYPO:0000991), if there is evidence that the intracellular level of a substance is also increased. synonym: "decreased accumulation of substance in growth medium" RELATED [PomBase:mah] synonym: "decreased level of substance in growth medium" EXACT [PomBase:mah] synonym: "decreased release of substance into growth medium" RELATED [PomBase:mah] synonym: "reduced concentration of substance in growth medium" EXACT [PomBase:mah] is_a: FYPO:0001155 ! altered effect on growth medium created_by: midori creation_date: 2012-03-07T03:47:46Z [Term] id: FYPO:0000817 name: increased concentration of pheromone in growth medium def: "A phenotype in which the concentration of a peptide pheromone released into the growth medium by cells is higher than normal." [PomBase:mah] synonym: "increased accumulation of pheromone in growth medium" RELATED [PomBase:mah] synonym: "increased concentration of peptide pheromone in growth medium" EXACT [PomBase:mah] synonym: "increased level of pheromone in growth medium" EXACT [PomBase:mah] synonym: "increased release of pheromone into growth medium" RELATED [PomBase:mah] synonym: "pheromone production: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000800 ! increased concentration of substance in growth medium created_by: midori creation_date: 2012-03-07T03:50:03Z [Term] id: FYPO:0000818 name: increased concentration of M-factor in growth medium def: "A phenotype in which the concentration of M-factor, the mating pheromone produced by mating type minus cells, released into the growth medium is higher than normal." [PomBase:mah] synonym: "increased accumulation of M-factor in growth medium" RELATED [PomBase:mah] synonym: "increased level of M-factor in growth medium" EXACT [PomBase:mah] synonym: "increased release of M-factor into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000817 ! increased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:12:02Z [Term] id: FYPO:0000819 name: increased concentration of P-factor in growth medium def: "A phenotype in which the concentration of P-factor, the mating pheromone produced by mating type plus cells, released into the growth medium is higher than normal." [PomBase:mah] synonym: "increased accumulation of P-factor in growth medium" RELATED [PomBase:mah] synonym: "increased level of P-factor in growth medium" EXACT [PomBase:mah] synonym: "increased release of P-factor into growth medium" RELATED [PomBase:mah] is_a: FYPO:0000817 ! increased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:14:04Z [Term] id: FYPO:0000820 name: decreased concentration of pheromone in growth medium def: "A phenotype in which the concentration of a peptide pheromone released into the growth medium by cells is lower than normal." [PomBase:mah] synonym: "decreased accumulation of pheromone in growth medium" RELATED [PomBase:mah] synonym: "decreased concentration of peptide pheromone in growth medium" EXACT [PomBase:mah] synonym: "decreased level of pheromone in growth medium" EXACT [PomBase:mah] synonym: "decreased release of pheromone into growth medium" RELATED [PomBase:mah] synonym: "pheromone production: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced concentration of pheromone in growth medium" EXACT [PomBase:mah] is_a: FYPO:0000816 ! decreased concentration of substance in growth medium created_by: midori creation_date: 2012-03-07T04:14:58Z [Term] id: FYPO:0000821 name: decreased concentration of M-factor in growth medium def: "A phenotype in which the concentration of M-factor, the mating pheromone produced by mating type minus cells, released into the growth medium is lower than normal." [PomBase:mah] synonym: "decreased accumulation of M-factor in growth medium" RELATED [PomBase:mah] synonym: "decreased level of M-factor in growth medium" EXACT [PomBase:mah] synonym: "decreased release of M-factor into growth medium" RELATED [PomBase:mah] synonym: "reduced concentration of M-factor in growth medium" EXACT [PomBase:mah] is_a: FYPO:0000820 ! decreased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:15:08Z [Term] id: FYPO:0000822 name: decreased concentration of P-factor in growth medium def: "A phenotype in which the concentration of P-factor, the mating pheromone produced by mating type plus cells, released into the growth medium is lower than normal." [PomBase:mah] synonym: "decreased accumulation of P-factor in growth medium" RELATED [PomBase:mah] synonym: "decreased level of P-factor in growth medium" EXACT [PomBase:mah] synonym: "decreased release of P-factor into growth medium" RELATED [PomBase:mah] synonym: "reduced concentration of P-factor in growth medium" EXACT [PomBase:mah] is_a: FYPO:0000820 ! decreased concentration of pheromone in growth medium created_by: midori creation_date: 2012-03-07T04:15:24Z [Term] id: FYPO:0000824 name: altered RNA level def: "A cell phenotype in which the amount of RNA measured in a cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal RNA level" EXACT [PomBase:mah] synonym: "altered cellular mRNA level" NARROW [PomBase:vw] synonym: "altered cellular RNA level" EXACT [PomBase:mah] synonym: "RNA accumulation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000989 ! altered level of substance in cell relationship: output_of FYPO:0000142 ! gene expression phenotype created_by: midori creation_date: 2012-03-08T03:02:56Z [Term] id: FYPO:0000825 name: increased RNA level during vegetative growth alt_id: FYPO:0001247 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased cellular mRNA level during vegetative growth" NARROW [PomBase:vw] synonym: "increased cellular RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "increased mRNA level during vegetative growth" NARROW [PomBase:mah] synonym: "increased RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "increased RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "RNA accumulation: increased during vegetative growth" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001326 ! altered RNA level during vegetative growth is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001890 ! increased RNA level created_by: midori creation_date: 2012-03-08T03:15:26Z [Term] id: FYPO:0000826 name: decreased RNA level def: "A cell phenotype in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. subset: qc_do_not_manually_annotate synonym: "decreased cellular mRNA level" NARROW [PomBase:vw] synonym: "decreased cellular RNA level" EXACT [PomBase:mah] synonym: "decreased RNA accumulation" RELATED [PomBase:mah] synonym: "reduced RNA level" EXACT [PomBase:mah] synonym: "RNA accumulation: decreased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000824 ! altered RNA level is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2012-03-08T03:16:30Z [Term] id: FYPO:0000827 name: advanced cell cycle progression def: "A cellular process phenotype in which cell cycle progression is advanced, one or more cell cycle phase transitions takes place earlier than normal." [PomBase:mah] synonym: "advanced cell cycle progression during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-03-08T03:30:50Z [Term] id: FYPO:0000828 name: advanced mitotic G1 phase progression def: "A cellular process phenotype in which progression through the G1 phase of the mitotic cell cycle is advanced." [PomBase:mah] synonym: "accelerated entry into G1" RELATED [PomBase:al] synonym: "advanced mitotic G1 phase progression during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic cell cycle advance in G1" EXACT [PomBase:mah] is_a: FYPO:0000602 ! abnormal mitotic G1 phase progression is_a: FYPO:0000827 ! advanced cell cycle progression created_by: midori creation_date: 2012-03-08T03:30:59Z [Term] id: FYPO:0000829 name: resistance to cisplatin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cisplatin than normal." [PomBase:mah] synonym: "resistance to cis-DPP" EXACT [CHEBI:27899] synonym: "resistance to cisplatin during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to DPP" BROAD [CHEBI:27899] synonym: "resistant to cisplatin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-03-08T03:43:33Z [Term] id: FYPO:0000830 name: resistance to vanadate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of vanadate ions than normal." [PomBase:mah] synonym: "resistance to vanadate during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to vanadium oxoanion" EXACT [CHEBI:30528] synonym: "resistant to vanadate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-03-08T03:44:55Z [Term] id: FYPO:0000831 name: resistance to actinomycin D def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of actinomycin D than normal." [PomBase:mah] synonym: "resistance to actinomycin D during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to actinomycin D" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-03-08T03:46:56Z [Term] id: FYPO:0000832 name: elongated nucleus def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is longer than normal." [PomBase:mah] synonym: "elongated nuclei" EXACT [PomBase:vw] synonym: "elongated nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "long nucleus" EXACT [PomBase:vw] is_a: FYPO:0000062 ! abnormal nuclear morphology created_by: midori creation_date: 2012-03-09T03:40:40Z [Term] id: FYPO:0000833 name: normal protein level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "normal protein level during vegetative growth" EXACT [PomBase:mah] synonym: "protein/peptide accumulation: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-03-09T03:50:03Z [Term] id: FYPO:0000834 name: altered protein level def: "A cell phenotype in which the amount of protein measured in a cell differs from normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. subset: qc_do_not_manually_annotate synonym: "abnormal protein level" EXACT [PomBase:mah] synonym: "altered cellular protein level" EXACT [PomBase:mah] synonym: "protein/peptide accumulation: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000989 ! altered level of substance in cell relationship: output_of FYPO:0000142 ! gene expression phenotype created_by: midori creation_date: 2012-03-09T03:50:50Z [Term] id: FYPO:0000835 name: decreased protein level def: "A cell phenotype in which the amount of protein measured in a cell is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. subset: qc_do_not_manually_annotate synonym: "decreased protein accumulation" RELATED [PomBase:mah] synonym: "protein/peptide accumulation: decreased" RELATED [SGD:phenotype_annotation] synonym: "reduced protein level" EXACT [PomBase:mah] is_a: FYPO:0000834 ! altered protein level is_a: FYPO:0000991 ! decreased level of substance in cell created_by: midori creation_date: 2012-03-09T03:50:57Z [Term] id: FYPO:0000836 name: increased protein level def: "A cell phenotype in which the amount of protein measured in a cell is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. subset: qc_do_not_manually_annotate synonym: "increased protein accumulation" RELATED [PomBase:mah] synonym: "protein/peptide accumulation: increased" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000834 ! altered protein level is_a: FYPO:0000990 ! increased level of substance in cell created_by: midori creation_date: 2012-03-09T03:51:05Z [Term] id: FYPO:0000837 name: cell cycle arrest in mitotic interphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in any part of interphase. Includes normal and abnormal occurrences of arrest." [PomBase:mah] synonym: "cell cycle arrest in mitotic interphase during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic interphase cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0001024 ! cell cycle arrest phenotype created_by: midori creation_date: 2012-03-09T04:18:58Z [Term] id: FYPO:0000838 name: normal protein localization to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to nucleus" EXACT [PomBase:mah] synonym: "normal protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization created_by: midori creation_date: 2012-03-12T03:24:23Z [Term] id: FYPO:0000839 name: elongated mononucleate aseptate cell def: "A cell phenotype in which a cell contains one nucleus, has no septum, is elongated, and is inviable." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated mononucleate aseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "inviable elongated mononucleate aseptate cell" EXACT [PomBase:mah, PomBase:vw] synonym: "long aseptate mononucleate cell" EXACT [PomBase:vw] is_a: FYPO:0001916 ! elongated mononucleate cell is_a: FYPO:0002066 ! inviable elongated aseptate cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000060 ! mononucleate relationship: has_part FYPO:0000949 ! aseptate relationship: has_part FYPO:0001489 ! inviable vegetative cell relationship: output_of FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2012-03-12T03:25:38Z [Term] id: FYPO:0000840 name: normal RNA level def: "A cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. subset: qc_do_not_manually_annotate synonym: "normal cellular RNA level" EXACT [PomBase:mah] synonym: "normal mRNA level" NARROW [PomBase:mah] synonym: "RNA accumulation: normal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0001076 ! normal level of substance in cell created_by: midori creation_date: 2012-03-14T12:06:03Z [Term] id: FYPO:0000841 name: sensitive to sodium dodecyl sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium dodecyl sulfate (SDS). Cells stop growing (and may die) at a concentration of SDS that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sodium dodecyl sulfate" EXACT [PomBase:mah] synonym: "sensitive to SDS" EXACT [CHEBI:8984] synonym: "sensitive to sodium dodecyl sulfate during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to sodium dodecyl sulphate" EXACT [CHEBI:8984] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-03-14T01:14:35Z [Term] id: FYPO:0000842 name: sensitive to ethanol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethanol. Cells stop growing (and may die) at a concentration of ethanol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to ethanol" EXACT [PomBase:mah] synonym: "sensitive to ethanol during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to ethyl alcohol" EXACT [CHEBI:16236] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-03-14T01:25:07Z [Term] id: FYPO:0000843 name: sensitive to dithiothreitol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1,4-dithiothreitol (DTT). Cells stop growing (and may die) at a concentration of dithiothreitol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to dithiothreitol" EXACT [PomBase:mah] synonym: "sensitive to 1,4-dithiothreitol" EXACT [CHEBI:18320] synonym: "sensitive to dithiothreitol during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to DTT" EXACT [PomBase:al] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-03-14T01:26:35Z [Term] id: FYPO:0000844 name: sensitive to mercaptoethanol def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mercaptoethanol. Cells stop growing (and may die) at a concentration of mercaptoethanol that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mercaptoethanol" EXACT [PomBase:mah] synonym: "sensitive to 2-sulfanylethanol" EXACT [CHEBI:41218] synonym: "sensitive to mercaptoethanol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-03-14T01:27:55Z [Term] id: FYPO:0000845 name: abnormal protein degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is abnormal. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds." [GO:0030163, PomBase:mah] synonym: "abnormal protein breakdown" EXACT [GO:0030163] synonym: "abnormal protein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein catabolism" EXACT [GO:0030163, PomBase:mah] synonym: "abnormal protein degradation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000328 ! abnormal protein metabolic process created_by: midori creation_date: 2012-03-14T02:33:44Z [Term] id: FYPO:0000846 name: decreased protein degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased." [PomBase:mah] synonym: "decreased protein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein catabolism" EXACT [GO:0030163, PomBase:mah] synonym: "decreased protein degradation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein degradation" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation relationship: has_output FYPO:0000836 ! increased protein level created_by: midori creation_date: 2012-03-14T02:57:05Z [Term] id: FYPO:0000847 name: increased protein degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is increased." [PomBase:mah] synonym: "increased protein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein catabolism" EXACT [GO:0030163, PomBase:mah] synonym: "increased protein degradation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000845 ! abnormal protein degradation created_by: midori creation_date: 2012-03-14T03:00:52Z [Term] id: FYPO:0000848 name: abnormal chromosome morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of one or more chromosomes is abnormal." [PomBase:mah] comment: Note that an abnormal chromosome organization process may, but does not necessarily, result in abnormal chromosome morphology. synonym: "abnormal chromosome morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000641 ! abnormal chromosome organization created_by: midori creation_date: 2012-03-14T03:09:26Z [Term] id: FYPO:0000849 name: cytoplasmic protein accumulation def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which specific proteins abnormally accumulate, and are constitutively located in, the cytoplasm." [PomBase:mah] synonym: "cytoplasmic accumulation of protein" EXACT [PomBase:mah] synonym: "cytoplasmic protein accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000762 ! protein accumulation is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-03-14T04:24:49Z [Term] id: FYPO:0000850 name: resistance to stress during vegetative growth def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to a stress." [PomBase:mah] synonym: "resistant to stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth is_a: FYPO:0002046 ! resistance to stress created_by: midori creation_date: 2012-03-15T10:55:12Z [Term] id: FYPO:0000851 name: resistance to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to osmotic stress." [PomBase:mah] synonym: "resistance to osmotic stress during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0000193 ! abnormal cellular response to osmotic stress is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2012-03-15T10:55:59Z [Term] id: FYPO:0000852 name: resistance to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to a salt stress." [PomBase:mah] synonym: "ionic stress resistance: increased" EXACT [SGD:phenotype_annotation] synonym: "resistant to salt stress" EXACT [PomBase:mah] synonym: "resistant to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000851 ! resistance to osmotic stress created_by: midori creation_date: 2012-03-15T10:56:15Z [Term] id: FYPO:0000853 name: abnormal nucleosome positioning def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "abnormal nucleosome positioning during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome spacing" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0001352 ! abnormal chromatin organization during vegetative growth created_by: midori creation_date: 2012-03-20T11:46:43Z [Term] id: FYPO:0000854 name: abnormal nucleosome positioning in euchromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of euchromatin is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "abnormal nucleosome positioning in euchromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome spacing in euchromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000853 ! abnormal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:52:16Z [Term] id: FYPO:0000855 name: abnormal nucleosome positioning in heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of heterochromatin is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "abnormal nucleosome positioning in heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleosome spacing in heterochromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000853 ! abnormal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:53:31Z [Term] id: FYPO:0000856 name: normal nucleosome positioning def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "normal nucleosome positioning during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome spacing" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-20T11:54:42Z [Term] id: FYPO:0000857 name: normal nucleosome positioning in euchromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of euchromatin is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "normal nucleosome positioning in euchromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome spacing in euchromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000856 ! normal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:55:39Z [Term] id: FYPO:0000858 name: normal nucleosome positioning in heterochromatin def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of heterochromatin is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another." [GO:0016584, PomBase:mah] synonym: "normal nucleosome positioning in heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleosome spacing in heterochromatin" EXACT [GO:0016584, PomBase:mah] is_a: FYPO:0000856 ! normal nucleosome positioning created_by: midori creation_date: 2012-03-20T11:55:49Z [Term] id: FYPO:0000859 name: normal metabolic process def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a cellular metabolic process is normal (i.e. indistinguishable from wild type). A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances." [GO:0044237, PomBase:mah] synonym: "normal cellular metabolic process" EXACT [GO:0044237, PomBase:mah] synonym: "normal metabolic process during vegetative growth" EXACT [PomBase:mah] synonym: "normal metabolism" EXACT [GO:0044237, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-03-20T12:10:04Z [Term] id: FYPO:0000860 name: abnormal metabolic process def: "A cellular process phenotype in which a cellular metabolic process is abnormal. A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances." [GO:0044237, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular metabolic process" EXACT [GO:0044237, PomBase:mah] synonym: "abnormal metabolism" EXACT [GO:0044237, PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2012-03-20T12:11:59Z [Term] id: FYPO:0000861 name: normal histone methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000549 ! normal protein modification created_by: midori creation_date: 2012-03-20T12:15:03Z [Term] id: FYPO:0000862 name: normal histone H3-K9 dimethylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal centromeric histone H3-K9 dimethylation " EXACT [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000861 ! normal histone methylation created_by: midori creation_date: 2012-03-20T12:18:40Z [Term] id: FYPO:0000863 name: normal histone H3-K9 dimethylation at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000862 ! normal histone H3-K9 dimethylation at centromere created_by: midori creation_date: 2012-03-20T12:20:16Z [Term] id: FYPO:0000864 name: abnormal histone H3-K9 trimethylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions is abnormal." [PomBase:mah] synonym: "abnormal centromeric histone H3-K9 trimethylation" EXACT [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation at centromere" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation at centromere" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 trimethylation at centromere" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000787 ! abnormal histone H3-K9 trimethylation created_by: midori creation_date: 2012-03-20T12:22:17Z [Term] id: FYPO:0000865 name: abnormal histone H3-K9 trimethylation at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation at centromere inner repeat" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation at centromere inner repeat" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 trimethylation at centromere inner repeat" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere created_by: midori creation_date: 2012-03-20T12:25:24Z [Term] id: FYPO:0000866 name: abnormal histone H3-K9 dimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 dimethylation" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation created_by: midori creation_date: 2012-03-20T12:28:22Z [Term] id: FYPO:0000867 name: abnormal histone H3-K9 dimethylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions is abnormal." [PomBase:mah] synonym: "abnormal centromeric histone H3-K9 dimethylation" EXACT [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation at centromere" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation at centromere" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 dimethylation at centromere" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000866 ! abnormal histone H3-K9 dimethylation created_by: midori creation_date: 2012-03-20T12:29:39Z [Term] id: FYPO:0000868 name: abnormal histone H3-K9 dimethylation at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation at centromere inner repeat" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation at centromere inner repeat" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 dimethylation at centromere inner repeat" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere created_by: midori creation_date: 2012-03-20T12:29:52Z [Term] id: FYPO:0000869 name: increased histone methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation occurs to a greater extent than normal. All histone methylation may be affected, or methylation of specific sites on specific histones may be increased." [PomBase:mah] synonym: "increased histone methylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation created_by: midori creation_date: 2012-03-20T12:32:05Z [Term] id: FYPO:0000870 name: decreased histone methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation occurs to a lower extent than normal. All histone methylation may be affected, or methylation of specific sites on specific histones may be decreased." [PomBase:mah] synonym: "decreased histone methylation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced histone methylation" EXACT [PomBase:mah] is_a: FYPO:0000457 ! abnormal histone methylation created_by: midori creation_date: 2012-03-20T12:32:18Z [Term] id: FYPO:0000871 name: increased histone H3-K9 methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone H3-K9 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9me" EXACT [GO:0051567, PomBase:mah] synonym: "increased histone lysine H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation is_a: FYPO:0000869 ! increased histone methylation created_by: midori creation_date: 2012-03-20T12:33:11Z [Term] id: FYPO:0000872 name: decreased histone H3-K9 methylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone H3-K9 methylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9me" EXACT [GO:0051567, PomBase:mah] synonym: "decreased histone lysine H3 K9 methylation" EXACT [GO:0051567, PomBase:mah] synonym: "reduced histone H3-K9 methylation" EXACT [PomBase:mah] is_a: FYPO:0000458 ! abnormal histone H3-K9 methylation is_a: FYPO:0000870 ! decreased histone methylation created_by: midori creation_date: 2012-03-20T12:34:25Z [Term] id: FYPO:0000873 name: increased histone H3-K9 dimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 dimethylation" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 dimethylation" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000866 ! abnormal histone H3-K9 dimethylation is_a: FYPO:0000871 ! increased histone H3-K9 methylation created_by: midori creation_date: 2012-03-20T01:25:01Z [Term] id: FYPO:0000874 name: increased histone H3-K9 dimethylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3-K9 dimethylation" EXACT [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at centromere" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 dimethylation at centromere" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 dimethylation at centromere" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere is_a: FYPO:0000873 ! increased histone H3-K9 dimethylation created_by: midori creation_date: 2012-03-20T01:25:10Z [Term] id: FYPO:0000875 name: increased histone H3-K9 dimethylation at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at centromere inner repeat" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 dimethylation at centromere inner repeat" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 dimethylation at centromere inner repeat" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000868 ! abnormal histone H3-K9 dimethylation at centromere inner repeat is_a: FYPO:0000874 ! increased histone H3-K9 dimethylation at centromere created_by: midori creation_date: 2012-03-20T01:25:53Z [Term] id: FYPO:0000876 name: decreased histone H3-K9 dimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 dimethylation" EXACT [PomBase:vw] synonym: "decreased histone lysine H3 K9 dimethylation" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation" EXACT [PomBase:mah] is_a: FYPO:0000866 ! abnormal histone H3-K9 dimethylation is_a: FYPO:0000872 ! decreased histone H3-K9 methylation created_by: midori creation_date: 2012-03-20T01:35:21Z [Term] id: FYPO:0000877 name: decreased histone H3-K9 dimethylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased centromeric histone H3-K9 dimethylation" EXACT [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at centromere" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at centromere" EXACT [PomBase:vw] synonym: "decreased histone lysine H3 K9 dimethylation at centromere" EXACT [GO:0036123, PomBase:mah] synonym: "reduced histone H3-K9 dimethylation at centromere" EXACT [PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere is_a: FYPO:0000876 ! decreased histone H3-K9 dimethylation created_by: midori creation_date: 2012-03-20T01:36:04Z [Term] id: FYPO:0000878 name: decreased histone H3-K9 dimethylation at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at centromere inner repeat" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at centromere inner repeat" EXACT [PomBase:vw] synonym: "reduced histone H3-K9 dimethylation at centromere inner repeat" EXACT [PomBase:mah] synonym: "v histone lysine H3 K9 dimethylation at centromere inner repeat" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000868 ! abnormal histone H3-K9 dimethylation at centromere inner repeat is_a: FYPO:0000877 ! decreased histone H3-K9 dimethylation at centromere created_by: midori creation_date: 2012-03-20T01:36:23Z [Term] id: FYPO:0000879 name: increased histone H3-K9 trimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 trimethylation" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 trimethylation" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 trimethylation" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000787 ! abnormal histone H3-K9 trimethylation is_a: FYPO:0000871 ! increased histone H3-K9 methylation created_by: midori creation_date: 2012-03-20T01:42:40Z [Term] id: FYPO:0000880 name: increased histone H3-K9 trimethylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3-K9 trimethylation" EXACT [PomBase:mah] synonym: "increased histone H3 K9 trimethylation at centromere" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 trimethylation at centromere" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 trimethylation at centromere" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere is_a: FYPO:0000879 ! increased histone H3-K9 trimethylation created_by: midori creation_date: 2012-03-20T01:42:53Z [Term] id: FYPO:0000881 name: increased histone H3-K9 trimethylation at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 trimethylation at centromere inner repeat" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 trimethylation at centromere inner repeat" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 trimethylation at centromere inner repeat" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000865 ! abnormal histone H3-K9 trimethylation at centromere inner repeat is_a: FYPO:0000880 ! increased histone H3-K9 trimethylation at centromere created_by: midori creation_date: 2012-03-20T01:43:01Z [Term] id: FYPO:0000882 name: decreased histone H3-K9 trimethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 trimethylation" EXACT [PomBase:vw] synonym: "decreased histone lysine H3 K9 trimethylation" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation" EXACT [PomBase:mah] is_a: FYPO:0000787 ! abnormal histone H3-K9 trimethylation is_a: FYPO:0000872 ! decreased histone H3-K9 methylation created_by: midori creation_date: 2012-03-20T01:47:31Z [Term] id: FYPO:0000883 name: decreased histone H3-K9 trimethylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased centromeric histone H3-K9 trimethylation" EXACT [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at centromere" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at centromere" EXACT [PomBase:vw] synonym: "decreased histone lysine H3 K9 trimethylation at centromere" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at centromere" EXACT [PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere is_a: FYPO:0000882 ! decreased histone H3-K9 trimethylation created_by: midori creation_date: 2012-03-20T01:47:38Z [Term] id: FYPO:0000884 name: decreased histone H3-K9 trimethylation at centromere inner repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at centromere inner repeat" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromere inner repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at centromere inner repeat" EXACT [PomBase:vw] synonym: "decreased histone lysine H3 K9 trimethylation at centromere inner repeat" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at centromere inner repeat" EXACT [PomBase:mah] is_a: FYPO:0000865 ! abnormal histone H3-K9 trimethylation at centromere inner repeat is_a: FYPO:0000883 ! decreased histone H3-K9 trimethylation at centromere created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000885 name: abnormal histone H3-K9 trimethylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 trimethylation at centromere outer repeat" EXACT [GO:0036124, PomBase:mah] synonym: "abnormal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 trimethylation at centromere outer repeat" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 trimethylation at centromere outer repeat" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000864 ! abnormal histone H3-K9 trimethylation at centromere created_by: midori creation_date: 2012-03-20T12:25:24Z [Term] id: FYPO:0000886 name: abnormal histone H3-K9 dimethylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3 K9 dimethylation at centromere outer repeat" EXACT [GO:0036123, PomBase:mah] synonym: "abnormal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 dimethylation at centromere outer repeat" EXACT [PomBase:vw] synonym: "abnormal histone lysine H3 K9 dimethylation at centromere outer repeat" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000867 ! abnormal histone H3-K9 dimethylation at centromere created_by: midori creation_date: 2012-03-20T12:29:52Z [Term] id: FYPO:0000887 name: increased histone H3-K9 dimethylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 dimethylation at centromere outer repeat" EXACT [GO:0036123, PomBase:mah] synonym: "increased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 dimethylation at centromere outer repeat" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 dimethylation at centromere outer repeat" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000874 ! increased histone H3-K9 dimethylation at centromere is_a: FYPO:0000886 ! abnormal histone H3-K9 dimethylation at centromere outer repeat created_by: midori creation_date: 2012-03-20T01:25:53Z [Term] id: FYPO:0000888 name: decreased histone H3-K9 dimethylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 dimethylation at centromere outer repeat" EXACT [GO:0036123, PomBase:mah] synonym: "decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 dimethylation at centromere outer repeat" EXACT [PomBase:vw] synonym: "reduced histone H3-K9 dimethylation at centromere outer repeat" EXACT [PomBase:mah] synonym: "v histone lysine H3 K9 dimethylation at centromere outer repeat" EXACT [GO:0036123, PomBase:mah] is_a: FYPO:0000877 ! decreased histone H3-K9 dimethylation at centromere is_a: FYPO:0000886 ! abnormal histone H3-K9 dimethylation at centromere outer repeat created_by: midori creation_date: 2012-03-20T01:36:23Z [Term] id: FYPO:0000889 name: increased histone H3-K9 trimethylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3 K9 trimethylation at centromere outer repeat" EXACT [GO:0036124, PomBase:mah] synonym: "increased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 trimethylation at centromere outer repeat" EXACT [PomBase:vw] synonym: "increased histone lysine H3 K9 trimethylation at centromere outer repeat" EXACT [GO:0036124, PomBase:mah] is_a: FYPO:0000880 ! increased histone H3-K9 trimethylation at centromere is_a: FYPO:0000885 ! abnormal histone H3-K9 trimethylation at centromere outer repeat created_by: midori creation_date: 2012-03-20T01:43:01Z [Term] id: FYPO:0000890 name: decreased histone H3-K9 trimethylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 trimethylation at centromere outer repeat" EXACT [GO:0036124, PomBase:mah] synonym: "decreased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K9 trimethylation at centromere outer repeat" EXACT [PomBase:vw] synonym: "decreased histone lysine H3 K9 trimethylation at centromere outer repeat" EXACT [GO:0036124, PomBase:mah] synonym: "reduced histone H3-K9 trimethylation at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0000883 ! decreased histone H3-K9 trimethylation at centromere is_a: FYPO:0000885 ! abnormal histone H3-K9 trimethylation at centromere outer repeat created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000891 name: abnormal histone H3-K9 acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 is abnormal." [PomBase:mah] synonym: "abnormal histone H3-K9 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K9 acetylation" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0000456 ! abnormal histone acetylation created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000892 name: increased histone H3-K9 acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K9 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 acetylation" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0000332 ! increased histone acetylation is_a: FYPO:0000891 ! abnormal histone H3-K9 acetylation created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000893 name: increased histone H3-K9 acetylation at centromere def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased centromeric histone H3K9 acetylation" EXACT [GO:0044154, PomBase:mah] synonym: "increased histone H3-K9 acetylation at centromere during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K9 acetylation at centromere" EXACT [GO:0044154, PomBase:mah] is_a: FYPO:0000892 ! increased histone H3-K9 acetylation created_by: midori creation_date: 2012-03-20T01:47:46Z [Term] id: FYPO:0000894 name: abnormal intracellular mitochondrion distribution def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which intracellular mitochondrion distribution, the process that results in the spatial arrangement of mitochondria in a cell, is abnormal." [GO:0048312, PomBase:mah] synonym: "abnormal intracellular mitochondrion distribution during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000489 ! abnormal mitochondrial distribution created_by: midori creation_date: 2012-03-29T02:42:20Z [Term] id: FYPO:0000895 name: mitochondrial aggregation def: "An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal." [PomBase:mah] synonym: "mitochondrial aggregation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000894 ! abnormal intracellular mitochondrion distribution is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-03-29T02:45:02Z [Term] id: FYPO:0000896 name: mitochondrial aggregation at cell tip def: "An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal, with a cluster at one or both ends of the cell." [PomBase:mah] synonym: "mitochondrial aggregation at cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000895 ! mitochondrial aggregation created_by: midori creation_date: 2012-03-29T02:53:52Z [Term] id: FYPO:0000897 name: normal mitochondrial fission def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, is normal (i.e. indistinguishable from wild type)." [GO:0000266, PomBase:mah] synonym: "normal mitochondrial division" EXACT [GO:0000266, PomBase:mah] synonym: "normal mitochondrial fission during vegetative growth" EXACT [PomBase:mah] synonym: "normal mitochondrial proliferation" RELATED [GO:0000266, PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-29T02:55:09Z [Term] id: FYPO:0000898 name: normal mitochondrial fusion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fusion, the merging of two or more separate mitochondria into a single compartment, is normal (i.e. indistinguishable from wild type)." [GO:0008053, PomBase:mah] synonym: "normal mitochondrial fusion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-29T02:56:39Z [Term] id: FYPO:0000899 name: normal microtubule cytoskeleton organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule cytoskeleton organization is normal (i.e. indistinguishable from wild type). Microtubule cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] synonym: "normal microtubule cytoskeleton organisation" EXACT [PomBase:mah] synonym: "normal microtubule cytoskeleton organization during vegetative growth" EXACT [PomBase:mah] synonym: "normal microtubule dynamics" EXACT [GO:0000226, PomBase:mah] synonym: "normal microtubule organization" RELATED [GO:0000226, PomBase:mah] is_a: FYPO:0000297 ! microtubule cytoskeleton organization phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-03-29T03:10:18Z [Term] id: FYPO:0000900 name: abnormal linear element assembly def: "A cellular process phenotype in which linear element assembly, the formation of a proteinaceous scaffold in association with S. pombe chromosomes during meiotic prophase, is abnormal." [PomBase:mah] synonym: "linear element formation" EXACT [GO:0030999, PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2012-03-30T04:40:50Z [Term] id: FYPO:0000901 name: abnormal microtubule polymerization or depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization or depolymerization, by the addition or removal of tubulin dimers respectively, is abnormal." [GO:0031109, PomBase:mah] synonym: "abnormal microtubule polymerization or depolymerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2012-03-29T03:29:01Z [Term] id: FYPO:0000902 name: abnormal microtubule depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is abnormal." [GO:0007019, PomBase:mah] synonym: "abnormal microtubule depolymerization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000901 ! abnormal microtubule polymerization or depolymerization created_by: midori creation_date: 2012-03-29T03:30:40Z [Term] id: FYPO:0000903 name: decreased microtubule depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, occurs to a lower extent than normal." [GO:0007019, PomBase:mah] synonym: "decreased microtubule depolymerization during vegetative growth" EXACT [PomBase:mah] synonym: "decreased microtubule shrinkage" RELATED [PomBase:vw] synonym: "increased microtubule stability" RELATED [PomBase:vw] synonym: "reduced microtubule depolymerization" EXACT [PomBase:mah] is_a: FYPO:0000902 ! abnormal microtubule depolymerization is_a: FYPO:0000904 ! decreased microtubule polymerization or depolymerization created_by: midori creation_date: 2012-03-29T03:32:17Z [Term] id: FYPO:0000904 name: decreased microtubule polymerization or depolymerization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization or depolymerization, by the addition or removal of tubulin dimers respectively, occurs to a lesser extent than normal. Microtubules are thus less dynamic than normal." [GO:0031109, PomBase:mah] synonym: "decreased microtubule dynamicity" RELATED [PomBase:vw] synonym: "decreased microtubule polymerization or depolymerization during vegetative growth" EXACT [PomBase:mah] synonym: "reduced microtubule polymerization or depolymerization" EXACT [PomBase:mah] is_a: FYPO:0000901 ! abnormal microtubule polymerization or depolymerization created_by: midori creation_date: 2012-03-29T03:33:35Z [Term] id: FYPO:0000905 name: abnormal protein ubiquitination def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, is abnormal." [PomBase:mah] comment: When using this term, it is recommended to note the specific protein(s) affected. synonym: "abnormal protein ubiquitination during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal protein ubiquitinylation" RELATED [GO:0016567, PomBase:mah] synonym: "abnormal protein ubiquitylation" EXACT [GO:0016567, PomBase:mah] is_a: FYPO:0000329 ! abnormal protein modification created_by: midori creation_date: 2012-03-30T04:12:43Z [Term] id: FYPO:0000906 name: abnormal mitochondrion inheritance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion inheritance is abnormal. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton." [GO:0000001, PomBase:mah] synonym: "abnormal mitochondrial inheritance" EXACT [GO:0000001, PomBase:mah] synonym: "abnormal mitochondrion inheritance during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000489 ! abnormal mitochondrial distribution created_by: midori creation_date: 2012-03-29T03:41:35Z [Term] id: FYPO:0000907 name: abolished mitochondrion inheritance def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion inheritance is abolished, resulting in the formation of a daughter cell that lacks mitochondria." [GO:0000001, PomBase:mah] synonym: "abolished mitochondrion inheritance during vegetative growth" EXACT [PomBase:mah] synonym: "asymmetric mitochondrial inheritance" RELATED [PomBase:vw] synonym: "mitochondrion inheritance abolished" EXACT [PomBase:mah] is_a: FYPO:0000906 ! abnormal mitochondrion inheritance created_by: midori creation_date: 2012-03-29T03:47:40Z [Term] id: FYPO:0000908 name: mixed population including viable and inviable cells def: "A mixed population phenotype in which some cells in a population are viable and others are inviable." [PomBase:mah] is_a: FYPO:0000317 ! mixed population is_a: FYPO:0002057 ! cell population viability relationship: includes_cells_with_phenotype FYPO:0000049 ! inviable cell relationship: includes_cells_with_phenotype FYPO:0000124 ! viable cell created_by: midori creation_date: 2012-03-29T03:52:40Z [Term] id: FYPO:0000909 name: abnormal protein localization to linear element def: "A cell phenotype in which the localization of a protein to linear elements is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to linear element" EXACT [GO:0036181, PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-03-30T04:48:31Z [Term] id: FYPO:0000910 name: RNA accumulation def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which specific RNA molecules abnormally accumulate in the cell, or in a part of the cell such as within an organelle." [PomBase:mah] synonym: "RNA accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000360 ! abnormal RNA localization created_by: midori creation_date: 2012-03-29T04:00:37Z [Term] id: FYPO:0000911 name: nuclear RNA accumulation def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which specific RNA molecules abnormally accumulate, and are constitutively located in, the nucleus." [PMID:12896976, PomBase:mah] synonym: "nuclear accumulation of RNA" EXACT [PomBase:mah] synonym: "nuclear RNA accumulation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000910 ! RNA accumulation is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-03-29T04:01:15Z [Term] id: FYPO:0000912 name: abolished protein ubiquitination def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, does not occur." [PomBase:mah] comment: When using this term, it is recommended to note the specific protein(s) affected. synonym: "abolished protein ubiquitination during vegetative growth" EXACT [PomBase:mah] synonym: "abolished protein ubiquitinylation" RELATED [GO:0016567, PomBase:mah] synonym: "abolished protein ubiquitylation" EXACT [GO:0016567, PomBase:mah] synonym: "protein ubiquitination abolished" EXACT [PomBase:mah] is_a: FYPO:0000544 ! abolished protein modification is_a: FYPO:0000905 ! abnormal protein ubiquitination created_by: midori creation_date: 2012-03-30T04:14:39Z [Term] id: FYPO:0000913 name: abnormal sporulation resulting in formation of ascus containing non-uniform spores def: "A sporulation phenotype that results in the formation of an ascus that contains spores of non-uniform size and DNA content." [PMID:20298435, PomBase:mah, PomBase:vw] synonym: "abnormal ascospore formation resulting in formation ascus containing non-uniform spores" EXACT [GO:0030437, PomBase:mah] synonym: "abnormal sporulation resulting in formation of asci containing non-uniform spores" RELATED [PomBase:mah] is_a: FYPO:0000121 ! abnormal sporulation created_by: midori creation_date: 2012-04-02T12:04:59Z [Term] id: FYPO:0000914 name: normal glutamate-ammonia ligase activity def: "A molecular function phenotype in which the observed rate of glutamate-ammonia ligase (also known as glutamine synthetase) activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glutamine synthetase activity" EXACT [GO:0004356, PomBase:mah] synonym: "normal glutamylhydroxamic synthetase activity" EXACT [GO:0004356] synonym: "normal GS activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-04-02T01:46:50Z [Term] id: FYPO:0000915 name: abnormal pyruvate dehydrogenase activity def: "A molecular function phenotype in which the observed rate of pyruvate dehydrogenase activity is abnormal." [PomBase:mah] synonym: "abnormal PDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2012-04-02T01:51:18Z [Term] id: FYPO:0000916 name: decreased pyruvate dehydrogenase activity def: "A molecular function phenotype in which the observed rate of pyruvate dehydrogenase activity is decreased." [PomBase:mah] synonym: "decreased PDH activity" EXACT [PMID:7851743, PomBase:al] synonym: "reduced pyruvate dehydrogenase activity" EXACT [PomBase:mah] is_a: FYPO:0000690 ! decreased oxidoreductase activity is_a: FYPO:0000915 ! abnormal pyruvate dehydrogenase activity created_by: midori creation_date: 2012-04-02T01:51:30Z [Term] id: FYPO:0000917 name: abnormal citrate (Si)-synthase activity def: "A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is abnormal." [PomBase:mah] synonym: "abnormal citrate synthase activity" BROAD [GO:0004108, PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-04-02T01:54:26Z [Term] id: FYPO:0000918 name: decreased citrate (Si)-synthase activity def: "A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is decreased." [PomBase:mah] synonym: "decreased citrate synthase activity" BROAD [GO:0004108, PMID:7851743, PomBase:al] synonym: "reduced citrate (Si)-synthase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0000917 ! abnormal citrate (Si)-synthase activity created_by: midori creation_date: 2012-04-02T01:54:32Z [Term] id: FYPO:0000919 name: increased citrate (Si)-synthase activity def: "A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is increased." [PomBase:mah] synonym: "increased citrate synthase activity" BROAD [GO:0004108, PMID:7851743, PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000917 ! abnormal citrate (Si)-synthase activity created_by: midori creation_date: 2012-04-02T02:24:33Z [Term] id: FYPO:0000920 name: abnormal aconitate hydratase activity def: "A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is abnormal." [PomBase:mah] synonym: "abnormal aconitase activity" EXACT [GO:0003994, PMID:7851743, PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-04-02T02:26:26Z [Term] id: FYPO:0000921 name: increased aconitate hydratase activity def: "A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is increased." [PomBase:mah] synonym: "increased aconitase activity" EXACT [GO:0003994, PMID:7851743, PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000920 ! abnormal aconitate hydratase activity created_by: midori creation_date: 2012-04-02T02:26:32Z [Term] id: FYPO:0000922 name: abnormal isocitrate dehydrogenase (NAD+) activity def: "A molecular function phenotype in which the observed rate of isocitrate dehydrogenase (NAD+) activity is abnormal." [PomBase:mah] synonym: "abnormal NAD-IDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2012-04-02T02:33:48Z [Term] id: FYPO:0000923 name: increased isocitrate dehydrogenase (NAD+) activity def: "A molecular function phenotype in which the observed rate of isocitrate dehydrogenase (NAD+) activity is increased." [PomBase:mah] synonym: "increased NAD-IDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0000922 ! abnormal isocitrate dehydrogenase (NAD+) activity created_by: midori creation_date: 2012-04-02T02:33:56Z [Term] id: FYPO:0000924 name: resistance to anisomycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of anisomycin than normal." [PomBase:mah] synonym: "resistance to anisomycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-04-02T02:43:27Z [Term] id: FYPO:0000925 name: unequal meiotic chromosome segregation def: "A cellular process phenotype in which chromosomes are not segregated equally to both spindle poles in a meiotic division." [PomBase:mah] is_a: FYPO:0000151 ! abnormal meiotic chromosome segregation created_by: midori creation_date: 2012-04-02T03:09:45Z [Term] id: FYPO:0000926 name: normal volume cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal volume." [PomBase:mah] synonym: "normal volume cells during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001124 ! normal cell size created_by: midori creation_date: 2012-04-03T03:12:03Z [Term] id: FYPO:0000927 name: abolished horsetail movement def: "A cellular process phenotype in which horsetail movement does not occur. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I." [PomBase:mah] synonym: "absent horsetail movement" EXACT [PomBase:vw] synonym: "dynein-driven meiotic oscillatory nuclear movement abolished" EXACT [GO:0030989, PomBase:mah] synonym: "horsetail movement abolished" EXACT [PomBase:mah] synonym: "horsetail nuclear movement abolished" EXACT [GO:0030989, PomBase:mah] is_a: FYPO:0000197 ! abnormal horsetail movement created_by: midori creation_date: 2012-04-02T03:23:19Z [Term] id: FYPO:0000928 name: abnormal protein localization to cell cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell cortex" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000929 name: decreased protein localization to cell cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell cortex" EXACT [PomBase:mah] synonym: "decreased protein localization to cell cortex during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cell cortex" EXACT [PomBase:mah] is_a: FYPO:0000928 ! abnormal protein localization to cell cortex created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000930 name: protein localization to cell cortex abolished def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to cell cortex" EXACT [PomBase:mah] synonym: "protein absent from cell cortex" RELATED [PomBase:mah] synonym: "protein localisation to cell cortex abolished" EXACT [PomBase:mah] synonym: "protein localization to cell cortex abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! protein localization abolished during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000931 name: abnormal protein localization to microtubule cytoskeleton def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with the microtubule cytoskeleton and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "abnormal protein localization to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000932 name: increased protein localization to microtubule cytoskeleton def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "increased protein localization to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000933 name: decreased protein localization to microtubule cytoskeleton def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "decreased protein localization to microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to microtubule cytoskeleton" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000934 name: protein localization to microtubule cytoskeleton abolished def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "protein absent from microtubule cytoskeleton" RELATED [PomBase:mah] synonym: "protein localisation to microtubule cytoskeleton abolished" EXACT [PomBase:mah] synonym: "protein localization to microtubule cytoskeleton abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001179 ! protein localization abolished during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000935 name: abnormal protein localization to cortical microtubule cytoskeleton def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with the cortical microtubule cytoskeleton and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cortical microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "abnormal protein localization to cortical microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000931 ! abnormal protein localization to microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000936 name: increased protein localization to cortical microtubule cytoskeleton def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to cortical microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "increased protein localization to cortical microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000932 ! increased protein localization to microtubule cytoskeleton is_a: FYPO:0000935 ! abnormal protein localization to cortical microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000937 name: decreased protein localization to cortical microtubule cytoskeleton def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cortical microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "decreased protein localization to cortical microtubule cytoskeleton during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to cortical microtubule cytoskeleton" EXACT [PomBase:mah] is_a: FYPO:0000933 ! decreased protein localization to microtubule cytoskeleton is_a: FYPO:0000935 ! abnormal protein localization to cortical microtubule cytoskeleton created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000938 name: protein localization to cortical microtubule cytoskeleton abolished def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localization to cortical microtubule cytoskeleton" EXACT [PomBase:mah] synonym: "protein absent from cortical microtubule cytoskeleton" RELATED [PomBase:mah] synonym: "protein localisation to cortical microtubule cytoskeleton abolished" EXACT [PomBase:mah] synonym: "protein localization to cortical microtubule cytoskeleton abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000934 ! protein localization to microtubule cytoskeleton abolished created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000939 name: abnormal protein localization to spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the spindle pole body is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the spindle pole body and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to spindle pole body" EXACT [PomBase:mah] synonym: "abnormal protein localization to SPB" EXACT [PomBase:mah] synonym: "abnormal protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000940 name: decreased protein localization to spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the spindle pole body is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to spindle pole body" EXACT [PomBase:mah] synonym: "decreased protein localization to SPB" EXACT [PomBase:mah] synonym: "decreased protein localization to spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to spindle pole body" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to spindle pole body created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000941 name: abolished protein localization to spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the spindle pole body does not occur." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein absent from spindle pole body" RELATED [PomBase:mah] synonym: "protein localisation to spindle pole body abolished" EXACT [PomBase:mah] synonym: "protein localization to SPB abolished" EXACT [PomBase:mah] synonym: "protein localization to spindle pole body abolished" EXACT [PomBase:mah] synonym: "protein localization to spindle pole body abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000939 ! abnormal protein localization to spindle pole body is_a: FYPO:0001179 ! protein localization abolished during vegetative growth created_by: midori creation_date: 2012-04-02T03:52:49Z [Term] id: FYPO:0000942 name: abnormal nucleus localization in prospore def: "A cellular process phenotype in which nucleus localization is abnormal in a prospore." [PomBase:mah] synonym: "abnormal nuclear localization in prospore" EXACT [PomBase:mah] synonym: "abnormal nucleus localisation in prospore" EXACT [PomBase:mah] synonym: "abnormal nucleus localization in ascospore-type prospore" EXACT [GO:0005628, PomBase:mah] is_a: FYPO:0000517 ! abnormal nucleus localization created_by: midori creation_date: 2012-04-02T04:22:13Z [Term] id: FYPO:0000943 name: normal spore morphology def: "A cell phenotype characterized by normal spore morphology." [PomBase:mah] is_a: FYPO:0000672 ! normal cell morphology created_by: midori creation_date: 2012-04-03T02:27:00Z [Term] id: FYPO:0000944 name: spore germination abolished, normal spore morphology def: "A cellular process phenotype in which spore germination does not occur, and spores have normal morphology." [PomBase:mah] is_a: FYPO:0000306 ! abolished spore germination relationship: has_part FYPO:0000306 ! abolished spore germination relationship: has_part FYPO:0000943 ! normal spore morphology created_by: midori creation_date: 2012-04-03T02:28:22Z [Term] id: FYPO:0000945 name: swollen spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, and has a larger volume than normal." [PomBase:mah] synonym: "enlarged volume spheroid vegetative cell" EXACT [PomBase:mah] synonym: "swollen rounded vegetative cell" RELATED [PomBase:mah] synonym: "swollen spheroid cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0000646 ! swollen vegetative cell relationship: has_part FYPO:0000021 ! spheroid vegetative cell relationship: has_part FYPO:0000025 ! swollen cell created_by: midori creation_date: 2012-04-03T03:14:05Z [Term] id: FYPO:0000946 name: normal volume spheroid vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, and has a normal volume." [PomBase:mah] synonym: "normal volume rounded vegetative cell" RELATED [PomBase:mah] synonym: "normal volume spheroid cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000021 ! spheroid vegetative cell is_a: FYPO:0001121 ! vegetative cell, abnormal cell shape, normal cell size relationship: has_part FYPO:0000021 ! spheroid vegetative cell relationship: has_part FYPO:0000926 ! normal volume cell created_by: midori creation_date: 2012-04-03T03:16:37Z [Term] id: FYPO:0000947 name: swollen spherical vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a sphere, and has a larger volume than normal." [PomBase:mah] synonym: "enlarged volume spherical vegetative cell" EXACT [PomBase:mah] synonym: "swollen orb during vegetative growth" EXACT [PomBase:vw] synonym: "swollen spherical cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000129 ! spherical vegetative cell is_a: FYPO:0000945 ! swollen spheroid vegetative cell relationship: has_part FYPO:0000025 ! swollen cell relationship: has_part FYPO:0000129 ! spherical vegetative cell created_by: midori creation_date: 2012-04-03T03:27:05Z [Term] id: FYPO:0000948 name: normal volume spherical vegetative cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a sphere, and has a normal volume." [PomBase:mah] synonym: "normal volume orb during vegetative growth" EXACT [PomBase:vw] synonym: "normal volume spherical cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000129 ! spherical vegetative cell is_a: FYPO:0000946 ! normal volume spheroid vegetative cell relationship: has_part FYPO:0000129 ! spherical vegetative cell relationship: has_part FYPO:0000926 ! normal volume cell created_by: midori creation_date: 2012-04-03T03:28:08Z [Term] id: FYPO:0000949 name: aseptate def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell does not contain a septum." [PomBase:mah] synonym: "absent septum" EXACT [PomBase:mah] synonym: "aseptate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth relationship: output_of FYPO:0000272 ! abolished septum formation created_by: midori creation_date: 2012-04-03T03:38:09Z [Term] id: FYPO:0000950 name: elongated aseptate cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell does not contain a septum and is elongated." [PomBase:mah] synonym: "elongated aseptate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000949 ! aseptate is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000949 ! aseptate created_by: midori creation_date: 2012-04-03T03:41:12Z [Term] id: FYPO:0000951 name: small inviable vegetative cell def: "A cell morphology in which a vegetative cell is inviable and has an abnormally low volume." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "essential; small vegetative cell" RELATED [PomBase:mah] synonym: "small inviable cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000645 ! small vegetative cell is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0000023 ! small cell relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-04-03T04:12:31Z [Term] id: FYPO:0000952 name: vacuoles present in greater numbers def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which cells contain more vacuoles than normal." [PomBase:mah] synonym: "additional vacuoles present" EXACT [PomBase:mah] synonym: "extra vacuoles" EXACT [PomBase:mah] synonym: "vacuoles present in greater numbers during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2012-04-03T04:18:23Z [Term] id: FYPO:0000953 name: normal cellular response to chemical stimulus def: "A cellular response phenotype in which the cellular response to a chemical stimulus is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0000627 ! normal cellular process created_by: midori creation_date: 2012-04-12T12:15:57Z [Term] id: FYPO:0000954 name: normal cell population growth on nickel cation def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing nickel cations." [PomBase:mah] synonym: "normal cell population growth in presence of nickel cations" EXACT [PomBase:mah] synonym: "normal cell population growth on nickel" EXACT [GO:0071289, PomBase:mah] synonym: "normal cellular response to nickel cation" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on nickel cation" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on nickel cation" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:18:01Z [Term] id: FYPO:0000955 name: normal cell population growth on lead ion def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing lead ions." [PomBase:mah] synonym: "normal cell population growth in presence of lead ion" EXACT [PomBase:mah] synonym: "normal cellular response to lead ion" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on lead ion" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on lead ion" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:21:54Z [Term] id: FYPO:0000956 name: normal cell population growth on bismuth def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing bismuth." [PomBase:mah] synonym: "normal cell population growth in presence of bismuth" EXACT [PomBase:mah] synonym: "normal cellular response to bismuth" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on bismuth" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on bismuth" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:22:52Z [Term] id: FYPO:0000957 name: normal cell population growth on methyl methanesulfonate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methyl methanesulfonate." [PomBase:mah] synonym: "normal cell population growth in presence of methyl methanesulfonate" EXACT [PomBase:mah] synonym: "normal cell population growth on MMS" EXACT [CHEBI:25255] synonym: "normal cellular response to methyl methanesulfonate" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on methyl methanesulfonate" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on methyl methanesulfonate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:23:26Z [Term] id: FYPO:0000958 name: normal cell population growth on mercaptoethanol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mercaptoethanol." [PomBase:mah] synonym: "normal cell population growth in presence of mercaptoethanol" EXACT [PomBase:mah] synonym: "normal cell population growth on 2-sulfanylethanol" EXACT [CHEBI:41218] synonym: "normal cellular response to mercaptoethanol" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on mercaptoethanol" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on mercaptoethanol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:25:12Z [Term] id: FYPO:0000959 name: normal cell population growth on sodium dodecyl sulfate def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium dodecyl sulfate (SDS." [PomBase:mah] synonym: "normal cell population growth in presence of sodium dodecyl sulfate" EXACT [PomBase:mah] synonym: "normal cell population growth on SDS" EXACT [CHEBI:8984] synonym: "normal cellular response to sodium dodecyl sulfate" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on sodium dodecyl sulfate" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on sodium dodecyl sulfate" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:28:02Z [Term] id: FYPO:0000960 name: normal cell population growth on ethanol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethanol." [PomBase:mah] synonym: "normal cell population growth in presence of ethanol" EXACT [PomBase:mah] synonym: "normal cell population growth on to ethyl alcohol" EXACT [PomBase:mah] synonym: "normal cellular response to ethanol" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on ethanol" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on ethanol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:35:28Z [Term] id: FYPO:0000961 name: normal cell population growth on sorbitol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sorbitol." [PomBase:mah] synonym: "normal cell population growth in presence of sorbitol" EXACT [PomBase:mah] synonym: "normal cell population growth on glucitol" EXACT [CHEBI:30199] synonym: "normal cellular response to sorbitol" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on sorbitol" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on sorbitol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:36:31Z [Term] id: FYPO:0000962 name: normal cell population growth on hydrogen peroxide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hydrogen peroxide." [PomBase:mah] synonym: "normal cell population growth in presence of hydrogen peroxide" EXACT [PomBase:mah] synonym: "normal cell population growth on H2O2" EXACT [CHEBI:16240] synonym: "normal cellular response to hydrogen peroxide" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on hydrogen peroxide" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:37:24Z [Term] id: FYPO:0000963 name: normal cell population growth on hydroxyurea def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hydroxyurea." [PomBase:mah] synonym: "normal cell population growth in presence of hydroxyurea" EXACT [PomBase:mah] synonym: "normal cell population growth on HU" EXACT [PomBase:mah] synonym: "normal growth on hydroxyurea" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on hydroxyurea" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:38:22Z [Term] id: FYPO:0000964 name: normal cell population growth on thiabendazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing thiabendazole." [PomBase:mah] synonym: "normal cell population growth in presence of thiabendazole" EXACT [PomBase:mah] synonym: "normal cell population growth on TBZ" EXACT [CHEBI:45979] synonym: "normal cellular response to thiabendazole" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on thiabendazole" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on thiabendazole" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-12T12:39:39Z [Term] id: FYPO:0000965 name: abnormal histone H3-K14 acetylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions is abnormal." [PomBase:mah] synonym: "abnormal histone H3-K14 acetylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal histone H3K14 acetylation at centromere outer repeat" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0000788 ! abnormal histone H3-K14 acetylation created_by: midori creation_date: 2012-04-12T12:56:33Z [Term] id: FYPO:0000966 name: increased histone H3-K14 acetylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal." [PomBase:mah] synonym: "increased histone H3-K14 acetylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "increased histone H3K14 acetylation at centromere outer repeat" EXACT [GO:0044154, PomBase:vw] is_a: FYPO:0000332 ! increased histone acetylation is_a: FYPO:0000547 ! increased protein modification is_a: FYPO:0000965 ! abnormal histone H3-K14 acetylation at centromere outer repeat created_by: midori creation_date: 2012-04-12T02:31:26Z [Term] id: FYPO:0000967 name: decreased histone H3-K14 acetylation at centromere outer repeat def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3-K14 acetylation at centromere outer repeat during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone H3K14 acetylation at centromere outer repeat" EXACT [GO:0044154, PomBase:vw] synonym: "reduced histone H3-K14 acetylation at centromere outer repeat" EXACT [PomBase:mah] is_a: FYPO:0000545 ! decreased protein modification is_a: FYPO:0000965 ! abnormal histone H3-K14 acetylation at centromere outer repeat is_a: FYPO:0001458 ! decreased histone H3-K14 acetylation created_by: midori creation_date: 2012-04-12T02:32:04Z [Term] id: FYPO:0000968 name: normal cellular response to stress def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a stress is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2012-04-19T01:25:21Z [Term] id: FYPO:0000969 name: normal cell population growth during cellular response to UV def: "A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) during a cellular response to ultraviolet light." [PomBase:mah] synonym: "normal cell population growth during cellular response to ultraviolet light" EXACT [PomBase:mah] synonym: "normal cellular response to UV" RELATED [PomBase:mah] synonym: "normal sensitivity to UV irradiation" RELATED [PomBase:vw] synonym: "normal vegetative cell population growth during cellular response to UV" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T01:25:40Z [Term] id: FYPO:0000970 name: sensitive to mitomycin C def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mitomycin C. Cells stop growing (and may die) at a concentration of mitomycin C that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to mitomycin C" EXACT [PomBase:mah] synonym: "sensitive to mitomycin C during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-04-19T01:38:22Z [Term] id: FYPO:0000972 name: increased number of Rad22 foci def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad22 accumulates is greater than normal." [PMID:22064477, PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'accumulation of double-strand break sites' (FYPO:0000455). synonym: "increased number of Rad22 foci during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-04-19T02:09:54Z [Term] id: FYPO:0000973 name: normal cellular response to copper ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to copper ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to copper" EXACT [GO:0071280] synonym: "normal cellular response to copper ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:30:26Z [Term] id: FYPO:0000974 name: normal cellular response to zinc ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to zinc ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to zinc" EXACT [GO:0071294] synonym: "normal cellular response to zinc ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:31:30Z [Term] id: FYPO:0000975 name: normal cellular response to mercury ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to mercury ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to mercury" EXACT [GO:0071248] synonym: "normal cellular response to mercury ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:32:52Z [Term] id: FYPO:0000976 name: normal cellular response to selenite ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to selenite ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to selenite" EXACT [PomBase:mah] synonym: "normal cellular response to selenite ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:33:28Z [Term] id: FYPO:0000977 name: normal cellular response to silver ion def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to silver ions is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to silver ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-19T02:34:05Z [Term] id: FYPO:0000978 name: normal cell population growth on mevastatin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mevastatin." [PomBase:mah] synonym: "normal cell population growth on compactin" EXACT [PomBase:al] synonym: "normal growth on mevastatin" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on mevastatin" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T04:43:12Z [Term] id: FYPO:0000979 name: normal cell population growth on miconazole def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing miconazole." [PomBase:mah] synonym: "normal growth on miconazole" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on miconazole" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T04:45:21Z [Term] id: FYPO:0000980 name: normal cell population growth on amphotericin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amphotericin B." [PomBase:mah] synonym: "normal growth on amphotericin B" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on amphotericin B" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-19T04:46:40Z [Term] id: FYPO:0000981 name: normal glutamate dehydrogenase (NAD+) activity def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAD+ as a cofactor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal NAD-GDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-04-20T02:09:01Z [Term] id: FYPO:0000982 name: abnormal glutamate dehydrogenase (NADP+) activity def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is abnormal." [PomBase:mah] synonym: "abnormal NADP-GDH activity" EXACT [PMID:7851743, PomBase:al] is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2012-04-20T02:12:39Z [Term] id: FYPO:0000983 name: decreased glutamate dehydrogenase (NADP+) activity def: "A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is decreased." [PomBase:mah] synonym: "decreased NADP-GDH activity" EXACT [PMID:7851743, PomBase:al] synonym: "reduced glutamate dehydrogenase (NADP+) activity" EXACT [PomBase:mah] is_a: FYPO:0000690 ! decreased oxidoreductase activity is_a: FYPO:0000982 ! abnormal glutamate dehydrogenase (NADP+) activity created_by: midori creation_date: 2012-04-20T02:12:45Z [Term] id: FYPO:0000984 name: abnormal transcriptional response to pheromone def: "A conjugation phenotype in which regulation of transcription in response to mating pheromone is abnormal." [PomBase:mah] synonym: "abnormal regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0046019, PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype is_a: FYPO:0000302 ! abnormal response to pheromone created_by: midori creation_date: 2012-04-25T12:26:50Z [Term] id: FYPO:0000985 name: transcriptional response to pheromone at increased pheromone level def: "A cellular response phenotype in which pheromone-responsive positive regulation of transcription occurs only at a higher level of pheromone than normal." [PomBase:mah] synonym: "decreased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "decreased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "resistant to pheromone" RELATED [PomBase:al, PomBase:mah] is_a: FYPO:0000623 ! abnormal positive regulation of transcription is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2012-04-25T12:29:45Z [Term] id: FYPO:0000986 name: increased transcriptional response to pheromone at normal pheromone level def: "A cellular response phenotype in which pheromone-responsive positive regulation of transcription results in a higher-than-normal level of transcription at a given pheromone level." [PomBase:mah] synonym: "increased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "increased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "sensitive to pheromone" RELATED [PomBase:al, PomBase:mah] is_a: FYPO:0000623 ! abnormal positive regulation of transcription is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2012-04-25T12:34:59Z [Term] id: FYPO:0000987 name: decreased transcriptional response to pheromone at normal pheromone level def: "A cellular response phenotype in which pheromone-responsive positive regulation of transcription results in a lower-than-normal level of transcription at a given pheromone level." [PomBase:mah] synonym: "decreased sensitivity of positive regulation of transcription from RNA polymerase II promoter by pheromones to pheromone" RELATED [PomBase:mah] synonym: "decreased transcriptional response to pheromone" RELATED [PomBase:mah] synonym: "reduced transcriptional response to pheromone at normal pheromone level" EXACT [PomBase:mah] synonym: "resistant to pheromone" RELATED [PomBase:al, PomBase:mah] is_a: FYPO:0000623 ! abnormal positive regulation of transcription is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2012-04-25T12:49:41Z [Term] id: FYPO:0000988 name: normal cellular response to arsenic def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to arsenic is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to arsenic during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-04-25T01:27:55Z [Term] id: FYPO:0000989 name: altered level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell differs from normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal level of substance in cell" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-04-25T02:06:49Z [Term] id: FYPO:0000990 name: increased level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell is higher than normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "increased accumulation of substance in cell" RELATED [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2012-04-25T02:07:28Z [Term] id: FYPO:0000991 name: decreased level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell is lower than normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "reduced level of substance in cell" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2012-04-25T02:08:00Z [Term] id: FYPO:0000992 name: altered cellular phosphatidylinositol-3-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular phosphatidylinositol-3-phosphate level" EXACT [PomBase:mah] synonym: "altered cellular phosphatidylinositol-3-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular PI-3-P level" EXACT [PomBase:al] synonym: "altered PI-3-P accumulation" RELATED [PomBase:al] is_a: FYPO:0001290 ! altered cellular phosphoinositide level created_by: midori creation_date: 2012-04-25T02:15:24Z [Term] id: FYPO:0000993 name: decreased cellular phosphatidylinositol-3-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular phosphatidylinositol-3-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular PI-3-P level" EXACT [PomBase:al] synonym: "decreased PI-3-P accumulation" RELATED [PomBase:al] synonym: "reduced cellular phosphatidylinositol-3-phosphate level" EXACT [PomBase:mah] is_a: FYPO:0000992 ! altered cellular phosphatidylinositol-3-phosphate level is_a: FYPO:0001289 ! decreased phospholipid level created_by: midori creation_date: 2012-04-25T02:18:12Z [Term] id: FYPO:0000994 name: increased cellular phosphatidylinositol-4-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular phosphatidylinositol-4-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PI-4-P level" EXACT [PomBase:al] synonym: "increased PI-4-P accumulation" RELATED [PomBase:al] is_a: FYPO:0001015 ! altered cellular phosphatidylinositol-4-phosphate level is_a: FYPO:0001286 ! increased cellular phosphoinositide level created_by: midori creation_date: 2012-04-25T02:19:52Z [Term] id: FYPO:0000995 name: abnormal cell morphology during nitrogen starvation def: "A cell phenotype in which cell morphology is altered when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2012-04-25T02:40:49Z [Term] id: FYPO:0000996 name: bottle-shaped cell during nitrogen starvation def: "A cell morphology phenotype in which the cell takes on a bottle shape, i.e. tapers at one end to a diameter smaller than the other, when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] synonym: "cell morphology, bottle/skittle during nitrogen starvation" EXACT [PomBase:mah] synonym: "skittle-shaped cell during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000014 ! bottle-shaped cell is_a: FYPO:0000995 ! abnormal cell morphology during nitrogen starvation created_by: midori creation_date: 2012-04-25T02:41:14Z [Term] id: FYPO:0000997 name: pear-shaped cell during nitrogen starvation def: "A cell morphology phenotype in which a cell is shaped in the form of a pear when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] comment: Discussing what this means; may rename. synonym: "cell morphology, pear shaped during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000020 ! pear-shaped cell is_a: FYPO:0000995 ! abnormal cell morphology during nitrogen starvation created_by: midori creation_date: 2012-04-25T02:41:20Z [Term] id: FYPO:0000998 name: elongated cell during nitrogen starvation def: "A cell morphology phenotype in which a cell becomes longer than normal, i.e. the maximum distance between the cell ends is greater than normal, when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] synonym: "cell morphology, elongated cell during nitrogen starvation" EXACT [PomBase:mah] synonym: "long cell during nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0000017 ! elongated cell is_a: FYPO:0000995 ! abnormal cell morphology during nitrogen starvation created_by: midori creation_date: 2012-04-25T02:41:23Z [Term] id: FYPO:0000999 name: enlarged nucleus during nitrogen starvation def: "A cellular structure phenotype in which the nucleus is larger than normal when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] synonym: "enlarged nuclei during nitrogen starvation" EXACT [PomBase:vw] is_a: FYPO:0000344 ! enlarged nucleus created_by: midori creation_date: 2012-04-25T03:07:07Z [Term] id: FYPO:0001000 name: normal cell cycle arrest in mitotic G1 phase during nitrogen starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally in G1 phase when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] synonym: "mitotic G1 phase arrest during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0000445 ! cell cycle arrest in mitotic G1 phase is_a: FYPO:0001025 ! normally arrested cell cycle progression is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-04-25T03:36:56Z [Term] id: FYPO:0001001 name: abnormal cell cycle arrest in mitotic G2 phase during nitrogen starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G2 phase, instead of the normal G1 phase, when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] synonym: "mitotic G2 phase arrest during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000710 ! abnormal cell cycle arrest in response to nitrogen starvation is_a: FYPO:0001151 ! cell cycle arrest in mitotic G2 phase during starvation is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-04-25T03:39:33Z [Term] id: FYPO:0001002 name: abolished cell division prior to G0 entry def: "A cellular process phenotype in which a cell does not undergo the normal two rounds of cell division prior to entering quiescence (G0)." [PMID:19366728, PomBase:mah] synonym: "cell division prior to G0 entry abolished" EXACT [PomBase:mah] synonym: "loss of pre-quiescence cell divisions following nitrogen starvation" EXACT [PomBase:al] is_a: FYPO:0000427 ! abnormal G1 to G0 transition created_by: midori creation_date: 2012-04-25T03:42:48Z [Term] id: FYPO:0001003 name: fragmented vacuoles during nitrogen starvation def: "A cell phenotype in which vacuoles are broken into more, smaller fragments than normal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "vacuole organization defects, fragmented vacuoles during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000281 ! fragmented vacuoles created_by: midori creation_date: 2012-04-25T03:48:58Z [Term] id: FYPO:0001004 name: viable upon G0 to G1 transition def: "A cell phenotype in which cells to resume growth normally upon exiting G0 phase." [PMID:19366728, PomBase:mah] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-04-25T03:50:33Z [Term] id: FYPO:0001005 name: DNA fragmentation during nitrogen starvation def: "A cell phenotype in which DNA is broken into small fragments when the cell is subject to nitrogen starvation." [PMID:19366728, PomBase:mah] is_a: FYPO:0000160 ! DNA fragmentation created_by: midori creation_date: 2012-04-25T04:01:19Z [Term] id: FYPO:0001006 name: multinucleate dumbbell-shaped cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus, is elongated, is inviable, and is shaped in the form of a dumbbell, i.e. having two connected, rounded parts of approximately equal size, tapering towards a narrower region in the center of the long axis. In a cell with this phenotype, the diameter at the ends may be much greater than in wild-type cells. Septal material may accumulate in patches at the cell surface, but no septum forms." [PMID:8834798, PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated, multinucleate dumbbell-shaped cell" EXACT [PomBase:mah] synonym: "inviable, elongated, multinucleate dumbbell-shaped cell" EXACT [PomBase:vw] synonym: "long, multinucleate dumbbell-shaped cell" EXACT [PomBase:vw] synonym: "multinucleate dumbbell-shaped cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000779 ! dumbbell-shaped cell is_a: FYPO:0002049 ! elongated multinucleate aseptate vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000061 ! multinucleate relationship: has_part FYPO:0000779 ! dumbbell-shaped cell relationship: has_part FYPO:0000949 ! aseptate created_by: midori creation_date: 2012-04-25T04:07:50Z [Term] id: FYPO:0001007 name: normal mitosis def: "A cellular process phenotype in which mitosis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "mitosis: normal" EXACT [PomBase:mah] synonym: "normal mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-04-25T04:16:58Z [Term] id: FYPO:0001008 name: contractile ring absent def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the actomyosin contractile ring is absent from the cell." [PomBase:mah] comment: In the absence of filamentous actin, a ring structure may form, but is not considered a contractile ring. synonym: "actomyosin contractile ring absent" EXACT [PomBase:mah] synonym: "contractile ring absent during vegetative growth" EXACT [PomBase:mah] synonym: "contractile ring actin absent" NARROW [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2012-04-25T04:19:40Z [Term] id: FYPO:0001009 name: abolished actomyosin contractile ring assembly def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filament bundles does not occur, resulting in the failure to form an actomyosin contractile ring." [PMID:19713940, PomBase:mah] comment: Note that a ring structure may form without filamentous actin, but a ring lacking F-actin is not considered a contractile ring. synonym: "abolished actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "abolished actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:mah] synonym: "abolished contractile ring assembly" EXACT [PomBase:mah] synonym: "abolished cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "abolished cytokinetic ring formation" RELATED [PomBase:vw] synonym: "actomyosin contractile ring assembly abolished" EXACT [PomBase:mah] synonym: "cytokinesis defects, contractile ring actin, absent" RELATED [PomBase:mah] is_a: FYPO:0000161 ! abnormal actomyosin contractile ring assembly relationship: has_output FYPO:0001008 ! contractile ring absent created_by: midori creation_date: 2012-04-25T04:37:10Z [Term] id: FYPO:0001010 name: abolished actin filament organization def: "A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of cytoskeletal structures comprising actin filaments does not occur." [PomBase:mah] synonym: "abolished actin filament organisation" EXACT [PomBase:mah] synonym: "abolished actin filament organization during vegetative growth" EXACT [PomBase:mah] synonym: "actin filament organization abolished" EXACT [PomBase:mah] is_a: FYPO:0000727 ! abnormal actin filament organization relationship: has_output FYPO:0001011 ! filamentous actin absent created_by: midori creation_date: 2012-04-25T04:55:17Z [Term] id: FYPO:0001011 name: filamentous actin absent def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain filamentous actin structures, such as cortical patches or dots, or rings." [PomBase:mah] synonym: "actin filaments absent" EXACT [PomBase:mah] synonym: "F-actin absent" EXACT [PomBase:mah] synonym: "filamentous actin absent during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2012-04-25T04:58:49Z [Term] id: FYPO:0001012 name: growth auxotrophic for uracil def: "Auxotrophy in which uracil is required for vegetative cell growth." [PomBase:mah] synonym: "growth auxotrophic for uracil during vegetative growth" EXACT [PomBase:mah] synonym: "uracil auxotrophy" EXACT [PomBase:mah] is_a: FYPO:0000128 ! auxotrophy created_by: midori creation_date: 2012-04-26T12:15:11Z [Term] id: FYPO:0001013 name: abnormal membrane organization def: "A cellular process phenotype in which cellular membrane organization is abnormal. Cellular membrane organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid bilayer membrane, such as the plasma membrane or an organelle membrane." [GO:0016044, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular membrane organization" EXACT [GO:0016044, PomBase:mah] synonym: "abnormal membrane organisation" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization created_by: midori creation_date: 2012-04-26T12:57:24Z [Term] id: FYPO:0001014 name: abnormal membrane organization during nitrogen starvation def: "A cellular process phenotype in which cellular membrane organization is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "abnormal cellular membrane organization" EXACT [GO:0016044, PomBase:mah] synonym: "abnormal membrane organisation" EXACT [PomBase:mah] is_a: FYPO:0001013 ! abnormal membrane organization created_by: midori creation_date: 2012-04-26T12:59:57Z [Term] id: FYPO:0001015 name: altered cellular phosphatidylinositol-4-phosphate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular phosphatidylinositol-4-phosphate level" EXACT [PomBase:mah] synonym: "altered cellular phosphatidylinositol-4-phosphate level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular PI-4-P level" EXACT [PomBase:al] synonym: "altered PI-4-P accumulation" RELATED [PomBase:al] is_a: FYPO:0001290 ! altered cellular phosphoinositide level created_by: midori creation_date: 2012-04-25T02:15:24Z [Term] id: FYPO:0001016 name: normal cell population growth on actinomycin D def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing actinomycin D." [PomBase:mah] synonym: "normal cell population growth in presence of actinomycin D" EXACT [PomBase:mah] synonym: "normal cellular response to actinomycin D" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on actinomycin D" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on actinomycin D" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-26T03:36:00Z [Term] id: FYPO:0001017 name: premature activation of bipolar cell growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which activation of bipolar cell growth occurs prematurely; results in early occurrence of new end take-off." [PomBase:mah] synonym: "early NETO" EXACT [PomBase:mah] synonym: "premature activation of bipolar vegetative cell growth" EXACT [PomBase:mah] synonym: "premature NETO" EXACT [PomBase:mah] synonym: "premature new end take-off" EXACT [PomBase:mah] is_a: FYPO:0000147 ! abnormal activation of bipolar cell growth created_by: midori creation_date: 2012-04-30T11:46:57Z [Term] id: FYPO:0001018 name: abolished activation of bipolar cell growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which activation of bipolar cell growth does not occur; results in absence of new end take-off." [PomBase:mah] synonym: "abolished activation of bipolar vegetative cell growth" EXACT [PomBase:mah] synonym: "abolished NETO" EXACT [PomBase:mah] synonym: "abolished new end take-off" EXACT [PomBase:mah] synonym: "absence of NETO" EXACT [PomBase:vw] synonym: "activation of bipolar cell growth abolished" EXACT [PomBase:mah] is_a: FYPO:0000147 ! abnormal activation of bipolar cell growth relationship: has_output FYPO:0001391 ! mislocalized septum, near new end created_by: midori creation_date: 2012-04-30T11:49:16Z [Term] id: FYPO:0001019 name: monopolar actin cortical patch localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only one end of a cell." [PomBase:mah] synonym: "monopolar actin cortical patch localisation" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000190 ! abnormal actin cortical patch localization created_by: midori creation_date: 2012-04-30T02:17:33Z [Term] id: FYPO:0001020 name: normal cell population growth on calcium ion def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing calcium ions." [PomBase:mah] synonym: "normal cell population growth in presence of calcium ions" EXACT [PomBase:mah] synonym: "normal cell population growth on calcium" EXACT [PomBase:mah] synonym: "normal cellular response to calcium ion" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on calcium ion" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on calcium ion" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-30T02:48:06Z [Term] id: FYPO:0001021 name: normal cell population growth during cellular response to osmotic stress def: "A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) during a cellular response to osmotic stress." [PomBase:mah] synonym: "normal cellular response to osmotic stress" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-30T02:50:20Z [Term] id: FYPO:0001022 name: normal cell population growth during cellular response to high osmolarity def: "A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) during a cellular response to high osmolarity." [PomBase:mah] synonym: "normal cell population growth during cellular response to hyperosmotic conditions" EXACT [PomBase:mah] synonym: "normal cellular response to high osmolarity" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to high osmolarity" EXACT [PomBase:mah] is_a: FYPO:0001021 ! normal cell population growth during cellular response to osmotic stress created_by: midori creation_date: 2012-04-30T02:50:58Z [Term] id: FYPO:0001023 name: normal cell population growth on cisplatin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cisplatin." [PomBase:mah] synonym: "normal cell population growth in presence of cisplatin" EXACT [PomBase:mah] synonym: "normal cell population growth on cis-DDP" EXACT [CHEBI:27899] synonym: "normal cell population growth on DDP" BROAD [PomBase:mah] synonym: "normal cellular response to cisplatin" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cisplatin" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on cisplatin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-04-30T02:59:00Z [Term] id: FYPO:0001024 name: cell cycle arrest phenotype def: "A cell cycle phenotype that affects or involves the normal or abnormal occurrence of cell cycle arrest. In cell cycle arrest, progression through the cell cycle is halted during one of the normal phases (G1, S, G2, or M)." [PomBase:mah] synonym: "cell cycle arrest phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast cell cycle arrest phenotype" EXACT [PomBase:mah] is_a: FYPO:0000631 ! cell cycle phenotype created_by: midori creation_date: 2012-05-09T01:15:41Z [Term] id: FYPO:0001025 name: normally arrested cell cycle progression def: "A cellular process phenotype in which cell cycle progression is arrested under conditions where arrest normally occurs." [PomBase:mah] synonym: "normal cell cycle arrest" EXACT [PomBase:mah] synonym: "normal cell cycle arrest in mitotic interphase" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0001024 ! cell cycle arrest phenotype created_by: midori creation_date: 2012-05-09T01:38:00Z [Term] id: FYPO:0001026 name: abnormal occurrence of normal cell cycle arrest def: "A cellular process phenotype in which a cell cycle arrest that normally occurs is abnormal (does not occur, or occurs abnormally)." [PomBase:mah] is_a: FYPO:0000011 ! abnormal cell cycle progression is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0001024 ! cell cycle arrest phenotype created_by: midori creation_date: 2012-05-09T01:43:53Z [Term] id: FYPO:0001027 name: normal cell cycle arrest in mitotic G2 phase during glucose starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally in G2 phase when the cell is subject to glucose starvation." [PomBase:al, PomBase:mah] comment: Note that this term should be used only for cell cycle arrest that occurs in mutants. For phenotypes affecting the G1 cell cycle that normally occurs in response to mating pheromone, see 'abnormal cell cycle arrest in response to pheromone' (FYPO:0000530) and its child terms. synonym: "mitotic G1 phase arrest during glucose starvation" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0001025 ! normally arrested cell cycle progression is_a: FYPO:0001151 ! cell cycle arrest in mitotic G2 phase during starvation is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-05-09T01:54:19Z [Term] id: FYPO:0001028 name: abnormal cell cycle arrest in mitotic interphase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in any part of interphase, under conditions where arrest is not a normal occurrence." [PomBase:mah] synonym: "abnormal mitotic interphase cell cycle arrest" EXACT [PomBase:mah] is_a: FYPO:0000502 ! abnormally arrested mitotic cell cycle is_a: FYPO:0000837 ! cell cycle arrest in mitotic interphase created_by: midori creation_date: 2012-05-09T02:46:23Z [Term] id: FYPO:0001029 name: resistance to canavanine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of canavanine than normal." [PomBase:mah] synonym: "resistance to canavanine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to canavanine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-05-15T16:55:19Z [Term] id: FYPO:0001030 name: normal cell population growth on dithiothreitol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing dithiothreitol." [PomBase:mah] synonym: "normal cell population growth in presence of dithiothreitol" EXACT [PomBase:mah] synonym: "normal cell population growth on 1,4-dithiothreitol" EXACT [CHEBI:18320] synonym: "normal cell population growth on DTT" EXACT [PomBase:mah] synonym: "normal cellular response to dithiothreitol" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on dithiothreitol" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on dithiothreitol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-05-09T04:26:29Z [Term] id: FYPO:0001031 name: accumulation of single-strand break sites def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of single-strand breaks in DNA is greater than normal." [PomBase:mah] comment: Because Rad22 often accumulates at double-strand breaks, consider also annotating to 'increased number of Rad22 foci' (FYPO:0000972). synonym: "accumulation of single-strand break sites during vegetative growth" EXACT [PomBase:mah] synonym: "increased number of single-strand break sites" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-05-09T04:33:36Z [Term] id: FYPO:0001032 name: resistance to camptothecin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of camptothecin than normal." [PomBase:mah] synonym: "resistance to camptothecin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to camptothecin" EXACT [PomBase:mah] synonym: "resistant to CPT" EXACT [CHEBI:27656, PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-05-09T04:35:09Z [Term] id: FYPO:0001033 name: normal double-strand break repair def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal double-strand break repair during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process is_a: FYPO:0000968 ! normal cellular response to stress is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-05-09T04:36:23Z [Term] id: FYPO:0001034 name: resistance to tunicamycin def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tunicamycin than normal." [PomBase:mah] synonym: "resistance to tunicamycin during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to TM" EXACT [PomBase:al] synonym: "resistant to tunicamycin" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-05-09T04:43:09Z [Term] id: FYPO:0001035 name: increased cell wall thickness def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thicker than normal." [PomBase:mah] synonym: "increased cell wall thickness during vegetative growth" EXACT [PomBase:mah] synonym: "thickened cell wall" EXACT [PomBase:mah] is_a: FYPO:0000351 ! abnormal cell wall morphology created_by: midori creation_date: 2012-05-09T04:44:26Z [Term] id: FYPO:0001036 name: delaminated cell wall def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is delaminated, i.e. one or more of its layers peels off." [PomBase:al, PomBase:mah] synonym: "delaminate cell wall" EXACT [PomBase:mah] synonym: "delaminated cell wall during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000351 ! abnormal cell wall morphology created_by: midori creation_date: 2012-05-09T04:45:40Z [Term] id: FYPO:0001037 name: normal cell population growth during cellular response to salt stress def: "A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress." [PomBase:mah] synonym: "normal cell population growth during cellular response to ionic osmotic stress" EXACT [GO:0071472, PomBase:mah] synonym: "normal cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal cellular salinity response" RELATED [GO:0071472, PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001021 ! normal cell population growth during cellular response to osmotic stress created_by: midori creation_date: 2012-05-09T04:57:53Z [Term] id: FYPO:0001038 name: increased protein phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal." [PomBase:mah] synonym: "increased protein phosphorylation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000547 ! increased protein modification is_a: FYPO:0000775 ! abnormal protein phosphorylation created_by: midori creation_date: 2012-05-09T05:01:01Z [Term] id: FYPO:0001039 name: abnormal thiamine diphosphokinase activity def: "A molecular function phenotype in which the observed rate of thiamine diphosphokinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-05-09T05:07:50Z [Term] id: FYPO:0001040 name: decreased thiamine diphosphokinase activity def: "A molecular function phenotype in which the observed rate of thiamine diphosphokinase activity is decreased." [PomBase:mah] synonym: "reduced thiamine diphosphokinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001039 ! abnormal thiamine diphosphokinase activity created_by: midori creation_date: 2012-05-09T05:07:58Z [Term] id: FYPO:0001041 name: increased cellular thiamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of thiamine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular thiamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased thiamine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-09T05:09:40Z [Term] id: FYPO:0001042 name: inviable after spore germination, single or double cell division def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and then dies." [PomBase:al, PomBase:mah] synonym: "essential; germinating spore, single or double cell division" RELATED [PomBase:mah] synonym: "inviable following spore germination, single or double cell division" EXACT [PomBase:mah] synonym: "inviable germinating spore, single or double cell division" RELATED [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination created_by: midori creation_date: 2012-05-09T05:12:57Z [Term] id: FYPO:0001043 name: increased mating efficiency def: "A biological process phenotype in which the observed mating efficiency is higher than normal." [PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). synonym: "mating efficiency: increased" EXACT [SGD:phenotype_annotation] is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2012-05-09T05:15:28Z [Term] id: FYPO:0001044 name: abnormal acid phosphatase activity def: "A molecular function phenotype in which the observed rate of acid phosphatase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-05-10T04:20:28Z [Term] id: FYPO:0001045 name: decreased acid phosphatase activity def: "A molecular function phenotype in which the observed rate of acid phosphatase activity is decreased." [PomBase:mah] synonym: "reduced acid phosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001044 ! abnormal acid phosphatase activity created_by: midori creation_date: 2012-05-10T04:20:35Z [Term] id: FYPO:0001046 name: premature mitosis def: "A cellular process phenotype in which cells enter mitosis earlier, relative to cell size or DNA integrity checkpoint status, than normal." [PomBase:mah] synonym: "early mitosis" EXACT [PomBase:mah] synonym: "premature mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001204 ! mistimed mitosis created_by: midori creation_date: 2012-05-11T01:28:00Z [Term] id: FYPO:0001047 name: mitotic catastrophe def: "An inviable phenotype in which a cell enters mitosis prematurely, undergoes abnormal mitotic chromosome segregation, and subsequently dies." [PomBase:mah] comment: Note that in higher eukaryotes, mitotic catastrophe is more broadly defined as any phenotype in which cells undergo an aberrant mitosis that arrests before completion, and subsequently die by necrosis or apoptosis. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "mitotic catastrophe during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000141 ! abnormal mitotic sister chromatid segregation is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-05-11T01:34:45Z [Term] id: FYPO:0001048 name: mitotic catastrophe with cut def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), and then undergoes septation and subsequently dies." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cut with mitotic catastrophe" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000229 ! cut is_a: FYPO:0001047 ! mitotic catastrophe relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0000229 ! cut relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-05-11T01:37:41Z [Term] id: FYPO:0001049 name: mitotic catastrophe, small cell def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis when smaller than wild type." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "mitotic catastrophe, small cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000951 ! small inviable vegetative cell is_a: FYPO:0001047 ! mitotic catastrophe relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0000951 ! small inviable vegetative cell relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-05-11T01:59:31Z [Term] id: FYPO:0001050 name: mitotic catastrophe, normal size cell def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis at the same size as wild type." [PomBase:mah] comment: Note that mitotic catastrophe in normal-size cells is usually interpreted to mean that cells enter mitosis despite failing to activate a DNA integrity checkpoint. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "mitotic catastrophe, normal size cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001047 ! mitotic catastrophe relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0001124 ! normal cell size relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-05-11T02:09:56Z [Term] id: FYPO:0001051 name: mitotic catastrophe, elongated cell def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis when longer than wild type." [PomBase:mah] comment: Note that mitotic catastrophe in elongated cells is usually interpreted to mean that cells enter mitosis despite failing to maintain a DNA integrity checkpoint. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "mitotic catastrophe, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic catastrophe, long cell" EXACT [PomBase:vw] is_a: FYPO:0001047 ! mitotic catastrophe is_a: FYPO:0001490 ! elongated inviable vegetative cell relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0001490 ! elongated inviable vegetative cell created_by: midori creation_date: 2012-05-11T02:16:25Z [Term] id: FYPO:0001052 name: mitotic catastrophe with cut, small cell def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis when smaller than wild type, and then undergoes septation and subsequently dies." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cut with mitotic catastrophe, small cell" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, small cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001048 ! mitotic catastrophe with cut is_a: FYPO:0001049 ! mitotic catastrophe, small cell relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0000229 ! cut relationship: has_part FYPO:0000951 ! small inviable vegetative cell relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-05-11T02:38:12Z [Term] id: FYPO:0001053 name: mitotic catastrophe with cut, normal size cell def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis at the same size as wild type, and then undergoes septation and subsequently dies." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cut with mitotic catastrophe, normal size cell" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, normal size cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001048 ! mitotic catastrophe with cut is_a: FYPO:0001050 ! mitotic catastrophe, normal size cell relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0000229 ! cut relationship: has_part FYPO:0001124 ! normal cell size relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-05-11T02:39:40Z [Term] id: FYPO:0001054 name: mitotic catastrophe with cut, elongated cell def: "An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), entering mitosis when longer than wild type, and then undergoes septation and subsequently dies." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "cut with mitotic catastrophe, elongated cell" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "mitotic catastrophe with cut, long cell" EXACT [PomBase:vw] is_a: FYPO:0001048 ! mitotic catastrophe with cut is_a: FYPO:0001051 ! mitotic catastrophe, elongated cell relationship: has_part FYPO:0000141 ! abnormal mitotic sister chromatid segregation relationship: has_part FYPO:0000229 ! cut relationship: has_part FYPO:0001204 ! mistimed mitosis relationship: has_part FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0001490 ! elongated inviable vegetative cell created_by: midori creation_date: 2012-05-11T02:39:47Z [Term] id: FYPO:0001055 name: cut following normal mitotic entry def: "An inviable phenotype in which a cell enters mitosis normally, but then undergoes septation despite abnormal chromosome segregation, and gives rise to inviable daughter cells." [PomBase:mah] synonym: "cut following normal entry into mitosis" EXACT [PomBase:mah] synonym: "cut following normal mitotic entry during vegetative growth" EXACT [PomBase:mah] synonym: "cut with normal mitotic entry" EXACT [PomBase:mah] is_a: FYPO:0000229 ! cut created_by: midori creation_date: 2012-05-11T02:46:40Z [Term] id: FYPO:0001056 name: normal arginine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-arginine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal arginine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal arginine import into cell" EXACT [PomBase:al] synonym: "normal arginine uptake" EXACT [GO:0043091] synonym: "normal L-arginine import" NARROW [PomBase:mah] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-05-11T03:49:08Z [Term] id: FYPO:0001057 name: abnormal amino acid import def: "A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal amino acid import into cell" EXACT [PomBase:al] synonym: "abnormal amino acid uptake" EXACT [GO:0043090] is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-05-11T03:54:42Z [Term] id: FYPO:0001058 name: decreased amino acid import def: "A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a lower extent than normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "decreased amino acid import into cell" EXACT [PomBase:al] synonym: "decreased amino acid uptake" EXACT [GO:0043090] synonym: "reduced amino acid import" EXACT [PomBase:mah] is_a: FYPO:0001057 ! abnormal amino acid import is_a: FYPO:0001336 ! transport phenotype during vegetative growth created_by: midori creation_date: 2012-05-11T03:55:46Z [Term] id: FYPO:0001059 name: abnormal glutamate import during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamate into the cell is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal glutamate import into cell" EXACT [PomBase:al] synonym: "abnormal glutamate uptake" EXACT [GO:0051938] synonym: "abnormal L-glutamate import" NARROW [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth is_a: FYPO:0001646 ! abnormal glutamate import created_by: midori creation_date: 2012-05-11T03:57:30Z [Term] id: FYPO:0001060 name: decreased glutamate import during vegetative growth def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamate into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased glutamate import into cell" EXACT [PomBase:al] synonym: "decreased glutamate uptake" EXACT [GO:0051938] synonym: "decreased L-glutamate import" NARROW [PomBase:mah] synonym: "reduced glutamate import" EXACT [PomBase:mah] is_a: FYPO:0001059 ! abnormal glutamate import during vegetative growth is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001649 ! decreased glutamate import created_by: midori creation_date: 2012-05-11T04:06:25Z [Term] id: FYPO:0001061 name: abnormal glutamine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamine into the cell is abnormal." [PomBase:mah] synonym: "abnormal glutamine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal glutamine import into cell" EXACT [PomBase:al] synonym: "abnormal glutamine uptake" EXACT [GO:0036229] synonym: "abnormal L-glutamine import" NARROW [PomBase:mah] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:08:09Z [Term] id: FYPO:0001062 name: decreased glutamine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased glutamine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glutamine import into cell" EXACT [PomBase:al] synonym: "decreased glutamine uptake" EXACT [GO:0036229] synonym: "decreased L-glutamine import" NARROW [PomBase:mah] synonym: "reduced glutamine import" EXACT [PomBase:mah] is_a: FYPO:0001061 ! abnormal glutamine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:08:19Z [Term] id: FYPO:0001063 name: abnormal glycine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glycine into the cell is abnormal." [PomBase:mah] synonym: "abnormal glycine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal glycine import into cell" EXACT [PomBase:al] synonym: "abnormal glycine uptake" EXACT [GO:0036233] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:10:09Z [Term] id: FYPO:0001064 name: decreased glycine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glycine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased glycine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased glycine import into cell" EXACT [PomBase:al] synonym: "decreased glycine uptake" EXACT [GO:0036233] synonym: "reduced glycine import" EXACT [PomBase:mah] is_a: FYPO:0001063 ! abnormal glycine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:10:17Z [Term] id: FYPO:0001065 name: abnormal threonine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of threonine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-threonine import" NARROW [PomBase:mah] synonym: "abnormal threonine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal threonine import into cell" EXACT [PomBase:al] synonym: "abnormal threonine uptake" EXACT [GO:0036231] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:11:34Z [Term] id: FYPO:0001066 name: decreased threonine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of threonine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-threonine import" NARROW [PomBase:mah] synonym: "decreased threonine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased threonine import into cell" EXACT [PomBase:al] synonym: "decreased threonine uptake" EXACT [GO:0036231] synonym: "reduced threonine import" EXACT [PomBase:mah] is_a: FYPO:0001065 ! abnormal threonine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:11:43Z [Term] id: FYPO:0001067 name: abnormal tyrosine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of tyrosine into the cell is abnormal." [PomBase:mah] synonym: "abnormal L-tyrosine import" NARROW [PomBase:mah] synonym: "abnormal tyrosine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal tyrosine import into cell" EXACT [PomBase:al] synonym: "abnormal tyrosine uptake" EXACT [GO:0036232] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:14:15Z [Term] id: FYPO:0001068 name: decreased tyrosine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of tyrosine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-tyrosine import" NARROW [PomBase:mah] synonym: "decreased tyrosine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased tyrosine import into cell" EXACT [PomBase:al] synonym: "decreased tyrosine uptake" EXACT [GO:0036232] synonym: "reduced tyrosine import" EXACT [PomBase:mah] is_a: FYPO:0001067 ! abnormal tyrosine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-05-11T04:14:20Z [Term] id: FYPO:0001069 name: increased duration of mitotic cell cycle phase def: "A cellular process phenotype in which the duration of one or more mitotic cell cycle phases is longer than normal." [PomBase:mah] synonym: "increased duration of mitotic cell cycle phase during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0000408 ! increased duration of cell cycle phase created_by: midori creation_date: 2012-05-31T14:19:07Z [Term] id: FYPO:0001070 name: decreased duration of mitotic cell cycle phase def: "A cellular process phenotype in which the duration of one or more mitotic cell cycle phases is shorter than normal." [PomBase:mah] synonym: "decreased duration of mitotic cell cycle phase during vegetative growth" EXACT [PomBase:mah] synonym: "reduced duration of mitotic cell cycle phase" EXACT [PomBase:mah] is_a: FYPO:0000059 ! abnormal mitotic cell cycle progression is_a: FYPO:0000410 ! decreased duration of cell cycle phase created_by: midori creation_date: 2012-05-31T14:19:54Z [Term] id: FYPO:0001071 name: normal transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001336 ! transport phenotype during vegetative growth created_by: midori creation_date: 2012-05-31T15:46:37Z [Term] id: FYPO:0001072 name: normal myo-inositol import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which myo-inositol import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal myo-inositol import during vegetative growth" EXACT [PomBase:mah] synonym: "normal myo-inositol import into cell" EXACT [PomBase:al] synonym: "normal myo-inositol uptake" EXACT [GO:0043091] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-05-31T15:59:13Z [Term] id: FYPO:0001073 name: abnormal myo-inositol import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of myo-inositol into the cell is abnormal." [PomBase:mah] synonym: "abnormal myo-inositol import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal myo-inositol import into cell" EXACT [PomBase:al] synonym: "abnormal myo-inositol uptake" EXACT [GO:0043090] is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth is_a: FYPO:0001720 ! abnormal transport created_by: midori creation_date: 2012-05-31T16:00:28Z [Term] id: FYPO:0001074 name: decreased myo-inositol import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of myo-inositol into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased myo-inositol import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased myo-inositol import into cell" EXACT [PomBase:al] synonym: "decreased myo-inositol uptake" EXACT [GO:0043090] synonym: "reduced myo-inositol import" EXACT [PomBase:mah] is_a: FYPO:0001073 ! abnormal myo-inositol import created_by: midori creation_date: 2012-05-31T16:00:49Z [Term] id: FYPO:0001075 name: normal cell population growth on papulacandin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing papulacandin B." [PomBase:mah] synonym: "normal cell population growth in presence of papulacandin B" EXACT [PomBase:mah] synonym: "normal cellular response to papulacandin B" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on papulacandin B" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on papulacandin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-05-31T16:05:26Z [Term] id: FYPO:0001076 name: normal level of substance in cell def: "A cell phenotype in which the amount of a specific substance measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000002 ! cell phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-05-31T16:27:42Z [Term] id: FYPO:0001077 name: normal polysaccharide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal polysaccharide accumulation" RELATED [PomBase:mah] synonym: "normal polysaccharide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:29:26Z [Term] id: FYPO:0001078 name: normal beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "normal beta-glucan accumulation" RELATED [PomBase:mah] synonym: "normal beta-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular beta-glucan level" EXACT [PomBase:al] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-05-31T16:30:57Z [Term] id: FYPO:0001079 name: normal galactomannan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular galactomannan level" EXACT [PomBase:al] synonym: "normal galactomannan accumulation" RELATED [PomBase:mah] synonym: "normal galactomannan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-05-31T16:33:06Z [Term] id: FYPO:0001080 name: decreased polysaccharide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular polysaccharide level" EXACT [PomBase:mah] synonym: "decreased polysaccharide accumulation" RELATED [PomBase:mah] synonym: "decreased polysaccharide level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced polysaccharide level" EXACT [PomBase:mah] is_a: FYPO:0001085 ! altered polysaccharide level is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:33:42Z [Term] id: FYPO:0001081 name: decreased cell wall alpha-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased cell wall alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "decreased cell wall alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "decreased cell wall alpha-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cell wall alpha-glucan level" EXACT [PomBase:mah] is_a: FYPO:0000027 ! abnormal cell wall is_a: FYPO:0001080 ! decreased polysaccharide level is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2012-05-31T16:35:00Z [Term] id: FYPO:0001082 name: decreased cell wall beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell wall is lower than normal." [PomBase:mah] synonym: "decreased cell wall beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "decreased cell wall beta-glucan accumulation" RELATED [PomBase:mah] synonym: "decreased cell wall beta-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cell wall beta-glucan level" EXACT [PomBase:mah] is_a: FYPO:0000027 ! abnormal cell wall is_a: FYPO:0001080 ! decreased polysaccharide level is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2012-05-31T16:36:19Z [Term] id: FYPO:0001083 name: increased polysaccharide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is greater than normal." [PomBase:mah] synonym: "increased cellular polysaccharide level" EXACT [PomBase:mah] synonym: "increased polysaccharide accumulation" RELATED [PomBase:mah] synonym: "increased polysaccharide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001085 ! altered polysaccharide level is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:37:01Z [Term] id: FYPO:0001084 name: increased cell wall alpha-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is greater than normal." [PomBase:mah] synonym: "increased cell wall alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "increased cell wall alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "increased cell wall alpha-glucan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000027 ! abnormal cell wall is_a: FYPO:0001083 ! increased polysaccharide level is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2012-05-31T16:37:12Z [Term] id: FYPO:0001085 name: altered polysaccharide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal polysaccharide level" EXACT [PomBase:mah] synonym: "altered cellular polysaccharide level" EXACT [PomBase:mah] synonym: "altered polysaccharide level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-05-31T16:39:05Z [Term] id: FYPO:0001086 name: normal glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-05-31T16:41:20Z [Term] id: FYPO:0001087 name: abnormal glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-05-31T16:41:54Z [Term] id: FYPO:0001088 name: decreased glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is decreased." [PomBase:mah] synonym: "reduced glucosyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001087 ! abnormal glucosyltransferase activity created_by: midori creation_date: 2012-05-31T16:42:14Z [Term] id: FYPO:0001089 name: increased glucosyltransferase activity def: "A molecular function phenotype in which the observed rate of a glucosyltransferase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001087 ! abnormal glucosyltransferase activity created_by: midori creation_date: 2012-05-31T16:42:35Z [Term] id: FYPO:0001090 name: resistance to heat shock during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] synonym: "resistant to heat shock during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth is_a: FYPO:0002045 ! resistance to heat shock created_by: midori creation_date: 2012-06-01T13:48:51Z [Term] id: FYPO:0001091 name: normal cellular response to heat shock def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to heat shock is normal (i.e. indistinguishable from wild type). Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] synonym: "normal cellular response to heat shock during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress created_by: midori creation_date: 2012-06-01T13:59:10Z [Term] id: FYPO:0001092 name: binding phenotype def: "A phenotype that affects the binding of a gene product to another substance." [PomBase:mah] synonym: "fission yeast binding phenotype" EXACT [PomBase:mah] is_a: FYPO:0000652 ! molecular function phenotype created_by: midori creation_date: 2012-06-01T14:07:32Z [Term] id: FYPO:0001093 name: abolished chromatin binding def: "A molecular function phenotype in which chromatin binding by a mutated gene product does not occur. The gene product may normally bind DNA, protein, or both in chromatin." [PomBase:mah] synonym: "abolished chromatin association" EXACT [PomBase:vw] synonym: "chromatin binding abolished" EXACT [PomBase:mah] is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-06-01T14:08:25Z [Term] id: FYPO:0001094 name: normal DNA replication origin binding def: "A molecular function phenotype in which occurrence of DNA binding at a replication origin by a mutated gene product is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal origin binding" EXACT [PomBase:mah] is_a: FYPO:0000655 ! normal DNA binding created_by: midori creation_date: 2012-06-01T14:23:10Z [Term] id: FYPO:0001095 name: abolished DNA replication origin binding def: "A molecular function phenotype in which DNA binding at a replication origin by a gene product does not occur, when the gene product or the bound DNA sequence is mutated." [PomBase:mah] synonym: "abolished origin binding" EXACT [PomBase:mah] synonym: "DNA replication origin binding abolished" EXACT [PomBase:mah] is_a: FYPO:0000659 ! abolished DNA binding created_by: midori creation_date: 2012-06-01T14:24:32Z [Term] id: FYPO:0001096 name: normal RNA level during nitrogen starvation def: "A cell phenotype in which the amount of RNA measured in a cell during nitrogen starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal cellular RNA level during nitrogen starvation" EXACT [PomBase:mah] synonym: "normal mRNA level during nitrogen starvation" NARROW [PomBase:mah] synonym: "normal RNA accumulation during nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level created_by: midori creation_date: 2012-06-01T14:32:55Z [Term] id: FYPO:0001097 name: sensitive to amitrole def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amitrole. Cells stop growing (and may die) at a concentration of amitrole that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to amitrole" EXACT [PomBase:mah] synonym: "sensitive to 3-amino-1,2,4-triazole" EXACT [CHEBI:40036, PomBase:al] synonym: "sensitive to amitrole during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-06-01T14:35:59Z [Term] id: FYPO:0001098 name: sensitive to 4-nitroquinoline N-oxide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-nitroquinoline N-oxide. Cells stop growing (and may die) at a concentration of 4-nitroquinoline N-oxide that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to 4-nitroquinoline N-oxide" EXACT [PomBase:mah] synonym: "sensitive to 4-nitroquinoline N-oxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-06-01T14:37:39Z [Term] id: FYPO:0001099 name: normal cell population growth on CCCP def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing carbonyl cyanide m-chlorophenyl hydrazone (CCCP)." [PomBase:mah] synonym: "normal cell population growth in presence of CCCP" EXACT [PomBase:mah] synonym: "normal cell population growth on carbonyl cyanide m-chlorophenyl hydrazone" EXACT [CHEBI:3259] synonym: "normal cellular response to CCCP" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on CCCP" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on CCCP" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-01T14:38:51Z [Term] id: FYPO:0001100 name: normal cell population growth on Gentian violet def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Gentian violet (also known as crystal violet)." [PomBase:mah] synonym: "normal cell population growth in presence of Gentian violet" EXACT [PomBase:mah] synonym: "normal cell population growth on crystal violet" EXACT [PomBase:mah] synonym: "normal cell population growth on {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride" EXACT [CHEBI:198346] synonym: "normal vegetative cell population growth on Gentian violet" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-01T14:39:48Z [Term] id: FYPO:0001101 name: decreased protein level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydrogen peroxide is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "decreased protein accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0001548 ! altered protein level during cellular response to hydrogen peroxide created_by: midori creation_date: 2012-06-01T14:47:37Z [Term] id: FYPO:0001102 name: increased protein level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydrogen peroxide is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "increased protein accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth is_a: FYPO:0001548 ! altered protein level during cellular response to hydrogen peroxide created_by: midori creation_date: 2012-06-01T14:48:16Z [Term] id: FYPO:0001103 name: resistance to hydrogen peroxide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hydrogen peroxide than normal." [PomBase:mah] synonym: "resistance to H2O2" EXACT [CHEBI:16240, PomBase:mah] synonym: "resistance to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-06-01T14:49:59Z [Term] id: FYPO:0001104 name: abnormal catalase activity def: "A molecular function phenotype in which the observed rate of catalase activity is abnormal." [PomBase:mah] is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2012-06-01T15:00:27Z [Term] id: FYPO:0001105 name: abolished catalase activity def: "A molecular function phenotype in which catalase activity is absent." [PomBase:mah] synonym: "catalase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001104 ! abnormal catalase activity created_by: midori creation_date: 2012-06-01T15:00:35Z [Term] id: FYPO:0001106 name: abnormal glutathione-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is abnormal." [PomBase:mah] is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2012-06-01T15:14:45Z [Term] id: FYPO:0001107 name: decreased glutathione-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is decreased." [PomBase:mah] synonym: "reduced glutathione-disulfide reductase activity" EXACT [PomBase:mah] is_a: FYPO:0000690 ! decreased oxidoreductase activity is_a: FYPO:0001106 ! abnormal glutathione-disulfide reductase activity created_by: midori creation_date: 2012-06-01T15:14:58Z [Term] id: FYPO:0001108 name: increased glutathione-disulfide reductase activity def: "A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is increased." [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001106 ! abnormal glutathione-disulfide reductase activity created_by: midori creation_date: 2012-06-01T15:15:04Z [Term] id: FYPO:0001109 name: resistance to menadione def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of menadione than normal." [PomBase:mah] synonym: "resistance to menadione during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to vitamin K3" RELATED [PomBase:al] synonym: "resistant to menadione" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-06-01T15:18:55Z [Term] id: FYPO:0001110 name: inviable after spore germination, multiple cell divisions, normal morphology def: "A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes two or more rounds of cell division, and then dies." [PomBase:al, PomBase:mah] synonym: "essential; germinating spore, multiple cell divisions, normal morphology" RELATED [PomBase:mah] synonym: "inviable following spore germination, multiple cell divisions, normal morphology" EXACT [PomBase:mah] synonym: "inviable germinating spore, multiple cell divisions, normal morphology" RELATED [PomBase:mah] synonym: "inviable germinating spore, multiple cell divisions, normal morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000316 ! inviable after spore germination relationship: has_output FYPO:0000299 ! microcolony formation created_by: midori creation_date: 2012-06-01T15:21:23Z [Term] id: FYPO:0001111 name: increased cellular glutathione disulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione disulfide (GSSG) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glutathione disulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular GSSG level" EXACT [CHEBI:17858, PomBase:al] synonym: "increased cellular oxidised glutathione level" EXACT [CHEBI:17858, PomBase:al] synonym: "increased glutathione disulfide accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-06-01T15:26:21Z [Term] id: FYPO:0001112 name: advanced cell cycle arrest in response to nitrogen starvation def: "A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation takes place earlier than normal." [PomBase:mah] is_a: FYPO:0000710 ! abnormal cell cycle arrest in response to nitrogen starvation created_by: midori creation_date: 2012-06-01T15:29:57Z [Term] id: FYPO:0001113 name: normal cellular response to pheromone def: "A cellular response phenotype in which the cellular response to a pheromone is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000953 ! normal cellular response to chemical stimulus created_by: midori creation_date: 2012-06-01T15:37:34Z [Term] id: FYPO:0001114 name: normal cellular response to M-factor def: "A cellular response phenotype in which the cellular response to M-factor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001113 ! normal cellular response to pheromone created_by: midori creation_date: 2012-06-01T15:39:05Z [Term] id: FYPO:0001115 name: normal cellular response to P-factor def: "A cellular response phenotype in which the cellular response to P-factor is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001113 ! normal cellular response to pheromone created_by: midori creation_date: 2012-06-01T15:39:33Z [Term] id: FYPO:0001116 name: decreased RNA level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased mRNA level during cellular response to hydrogen peroxide" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] is_a: FYPO:0001280 ! decreased RNA level during cellular response to oxidative stress created_by: midori creation_date: 2012-06-07T11:25:57Z [Term] id: FYPO:0001117 name: decreased RNA level during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased cellular mRNA level during vegetative growth" NARROW [PomBase:vw] synonym: "decreased cellular RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased RNA accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level is_a: FYPO:0001326 ! altered RNA level during vegetative growth is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-06-07T11:31:36Z [Term] id: FYPO:0001118 name: abnormal vegetative cell morphology def: "A cell phenotype in which cell morphology is altered in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal cell morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-06-07T11:45:38Z [Term] id: FYPO:0001119 name: bottle-shaped cell during vegetative growth def: "A cell morphology phenotype in which the cell takes on a bottle shape, i.e. tapers at one end to a diameter smaller than the other, in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "cell morphology, bottle/skittle during vegetative growth" EXACT [PomBase:mah] synonym: "skittle-shaped cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000014 ! bottle-shaped cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2012-06-07T11:47:07Z [Term] id: FYPO:0001120 name: pear-shaped cell during vegetative growth def: "A cell morphology phenotype in which a cell is shaped in the form of a pear in the vegetative growth phase of the life cycle." [PomBase:mah] comment: Discussing what this means; may rename. synonym: "cell morphology, pear shaped during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000020 ! pear-shaped cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2012-06-07T11:47:18Z [Term] id: FYPO:0001121 name: vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype in which cell shape is altered, but cell size remains normal, in the vegetative growth phase of the life cycle." [PomBase:mah, PomBase:vw] synonym: "abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] synonym: "lumpy" RELATED [PomBase:vw] is_a: FYPO:0001118 ! abnormal vegetative cell morphology relationship: has_part FYPO:0001124 ! normal cell size relationship: has_part FYPO:0001126 ! abnormal cell shape created_by: midori creation_date: 2012-06-07T11:56:50Z [Term] id: FYPO:0001122 name: elongated vegetative cell def: "A cell phenotype in which a cell is elongated in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "long vegetative cell" EXACT [PomBase:vw] is_a: FYPO:0000017 ! elongated cell is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2012-06-07T13:10:57Z [Term] id: FYPO:0001123 name: elongated spore def: "A cell phenotype in which a spore is longer than normal." [PomBase:mah] synonym: "long spores" EXACT [PomBase:vw] is_a: FYPO:0000017 ! elongated cell is_a: FYPO:0000348 ! abnormal spore morphology created_by: midori creation_date: 2012-06-07T13:11:48Z [Term] id: FYPO:0001124 name: normal cell size def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal volume and dimensions." [PomBase:mah] synonym: "normal cell size during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001315 ! normal cell morphology during vegetative growth created_by: midori creation_date: 2012-06-07T15:28:36Z [Term] id: FYPO:0001125 name: normal cell shape def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal shape." [PomBase:mah] synonym: "normal cell shape during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001315 ! normal cell morphology during vegetative growth created_by: midori creation_date: 2012-06-07T15:28:36Z [Term] id: FYPO:0001126 name: abnormal cell shape def: "A cell morphology phenotype in which a cell has an abnormal shape." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2012-06-07T15:28:36Z [Term] id: FYPO:0001127 name: abnormal cell size def: "A cell morphology phenotype in which a cell has a volume or dimensions that differ from normal." [PomBase:mah] is_a: FYPO:0000005 ! abnormal cell morphology created_by: midori creation_date: 2012-06-07T16:00:41Z [Term] id: FYPO:0001128 name: decreased septation index def: "A cell population phenotype in which the septation index is lower than normal. The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for wild type." [PomBase:mah] synonym: "decreased septation" RELATED [PomBase:mah] synonym: "reduced septation index" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype relationship: includes_cells_with_phenotype FYPO:0000567 ! decreased duration of septation created_by: midori creation_date: 2012-06-08T11:45:02Z [Term] id: FYPO:0001129 name: abnormal protein localization to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to nucleus" EXACT [GO:0034504, PomBase:mah] synonym: "abnormal protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-06-08T12:02:23Z [Term] id: FYPO:0001130 name: increased protein localization to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "increased protein localisation to nucleus" EXACT [GO:0034504, PomBase:mah] synonym: "increased protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus created_by: midori creation_date: 2012-06-08T12:04:38Z [Term] id: FYPO:0001131 name: abnormal protein localization to heterochromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein heterochromatin to chromatin" EXACT [PomBase:mah] synonym: "abnormal protein localisation to heterochromatin" EXACT [PomBase:mah] synonym: "abnormal protein localization to heterochromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth created_by: midori creation_date: 2012-06-08T15:14:15Z [Term] id: FYPO:0001132 name: abolished protein localization to heterochromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to heterochromatin" EXACT [PomBase:mah] synonym: "abolished protein localization to heterochromatin during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to heterochromatin abolished" EXACT [PomBase:mah] is_a: FYPO:0001131 ! abnormal protein localization to heterochromatin is_a: FYPO:0001508 ! abolished protein localization to chromatin during vegetative growth created_by: midori creation_date: 2012-06-08T15:15:02Z [Term] id: FYPO:0001133 name: normal DNA replication def: "A cellular process phenotype in which DNA replication is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal DNA replication during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000859 ! normal metabolic process is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-06-08T15:41:39Z [Term] id: FYPO:0001134 name: normal 18S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 18S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal 18S rRNA accumulation" RELATED [PomBase:mah] synonym: "normal 18S rRNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-06-08T16:38:01Z [Term] id: FYPO:0001135 name: increased 35S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the 35S rRNA primary transcript measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased 35S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "increased 35S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] synonym: "increased 35S rRNA primary transcript level" EXACT [PomBase:mah, SO:0000325] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-06-08T16:40:54Z [Term] id: FYPO:0001136 name: increased 27S rRNA precursor level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 27S rRNA precursor measured in a cell is higher than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased 27S rRNA precursor accumulation" RELATED [PomBase:mah] synonym: "increased 27S rRNA precursor level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-06-08T16:44:25Z [Term] id: FYPO:0001137 name: decreased 25S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 25S rRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 25S rRNA accumulation" RELATED [PomBase:mah] synonym: "decreased 25S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature 25S rRNA transcript" EXACT [PomBase:vw] synonym: "reduced 25S rRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-06-08T16:45:47Z [Term] id: FYPO:0001138 name: decreased 5.8S rRNA level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 5.8S rRNA measured in a cell is lower than normal." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased 5.8S rRNA accumulation" RELATED [PomBase:mah] synonym: "decreased 5.8S rRNA level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased mature 5.8S rRNA transcript" EXACT [PomBase:vw] synonym: "reduced 5.8S rRNA level" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-06-08T16:47:19Z [Term] id: FYPO:0001139 name: abnormal leucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell is abnormal." [PomBase:mah] synonym: "abnormal leucine import during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal leucine import into cell" EXACT [PomBase:al] synonym: "abnormal leucine uptake" EXACT [GO:0036233] is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-06-11T14:24:42Z [Term] id: FYPO:0001140 name: decreased leucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased leucine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased leucine import into cell" EXACT [PomBase:al] synonym: "decreased leucine uptake" EXACT [GO:0036233] synonym: "reduced leucine import" EXACT [PomBase:mah] is_a: FYPO:0001139 ! abnormal leucine import is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth created_by: midori creation_date: 2012-06-11T14:26:26Z [Term] id: FYPO:0001141 name: abolished transcriptional response to pheromone def: "A conjugation phenotype in which regulation of transcription in response to mating pheromone is abolished." [PomBase:mah] synonym: "abolished regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [GO:0046019, PomBase:mah] synonym: "transcriptional response to pheromone abolished" EXACT [PomBase:mah] is_a: FYPO:0000984 ! abnormal transcriptional response to pheromone created_by: midori creation_date: 2012-06-11T14:48:00Z [Term] id: FYPO:0001142 name: normal Man8GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is normal (i.e. indistinguishable from wild type). Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:64048, CHEBI:64052, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "normal cellular Man8GlcNAc level" EXACT [PomBase:al] synonym: "normal Man8GlcNAc accumulation" RELATED [PomBase:mah] synonym: "normal Man8GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "normal Man8GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-06-14T15:52:46Z [Term] id: FYPO:0001143 name: normal Man9GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man9GlcNAc2 measured in a cell is normal (i.e. indistinguishable from wild type). Man9GlcNAc2 is any N-glycan that consists of a branched undecasaccharide consisting of nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59579, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "normal cellular Man9GlcNAc level" EXACT [PomBase:al] synonym: "normal Man9GlcNAc accumulation" RELATED [PomBase:mah] synonym: "normal Man9GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "normal Man9GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-06-14T15:55:35Z [Term] id: FYPO:0001144 name: decreased Man8GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is lower than normal. Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:64048, CHEBI:64052, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "decreased cellular Man8GlcNAc level" EXACT [PomBase:al] synonym: "decreased Man8GlcNAc accumulation" RELATED [PomBase:mah] synonym: "decreased Man8GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Man8GlcNAc2 level" EXACT [PomBase:mah] synonym: "reduced Man8GlcNAc level" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level created_by: midori creation_date: 2012-06-14T15:59:43Z [Term] id: FYPO:0001145 name: increased Man9GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man9GlcNAc2 measured in a cell is higher than normal. Man9GlcNAc2 is any N-glycan that consists of a branched undecasaccharide consisting of nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59579, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "increased cellular Man9GlcNAc level" EXACT [PomBase:al] synonym: "increased Man9GlcNAc accumulation" RELATED [PomBase:mah] synonym: "increased Man9GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "increased Man9GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level created_by: midori creation_date: 2012-06-14T16:00:30Z [Term] id: FYPO:0001146 name: decreased misfolded glycoprotein degradation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of misfolded glycoprotein degradation is decreased." [PomBase:mah] synonym: "decreased misfolded glycoprotein catabolic process" EXACT [GO:0030163, PomBase:mah] synonym: "decreased misfolded glycoprotein catabolism" EXACT [PomBase:mah] synonym: "decreased misfolded glycoprotein degradation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein degradation" EXACT [PomBase:mah] is_a: FYPO:0000846 ! decreased protein degradation created_by: midori creation_date: 2012-06-14T16:04:32Z [Term] id: FYPO:0001147 name: normal mating efficiency def: "A biological process phenotype in which the observed mating efficiency is normal (i.e. the same as in wild-type cells)." [PomBase:al, PomBase:mah] comment: Note that mating efficiency is often measured by counting zygotes plus asci, sometimes also including spores, so a change in measured mating efficiency may reflect a change in conjugation frequency (see FYPO:0000031 and its descendants), a change in sporulation (see FYPO:0000121 and its descendants), or both. For this reason, this term is not a child of 'mating phenotype' (FYPO:0000031). is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0000300 ! biological process phenotype created_by: midori creation_date: 2012-06-14T16:21:22Z [Term] id: FYPO:0001148 name: normal cell population growth on amiloride def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amiloride." [PomBase:mah] synonym: "normal cell population growth in presence of amiloride" EXACT [PomBase:mah] synonym: "normal cellular response to amiloride" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on amiloride" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on amiloride" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-14T16:30:50Z [Term] id: FYPO:0001149 name: normal cell population growth on methylamine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methylamine." [PomBase:mah] synonym: "normal cell population growth in presence of methylamine" EXACT [PomBase:mah] synonym: "normal cellular response to methylamine" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on methylamine" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on methylamine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-14T16:33:06Z [Term] id: FYPO:0001150 name: sensitive to methylamine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methylamine. Cells stop growing (and may die) at a concentration of methylamine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to methylamine" EXACT [PomBase:mah] synonym: "sensitive to methylamine during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-06-14T16:34:29Z [Term] id: FYPO:0001151 name: cell cycle arrest in mitotic G2 phase during starvation def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G2 phase when the cell is subject to starvation for one or more nutrients." [PMID:19366728, PomBase:mah] synonym: "mitotic G2 phase arrest during starvation" EXACT [PomBase:mah] is_a: FYPO:0000446 ! cell cycle arrest in mitotic G2 phase created_by: midori creation_date: 2012-06-14T16:45:50Z [Term] id: FYPO:0001152 name: decreased RNA level during nitrogen starvation def: "A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to nitrogen starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased RNA accumulation during nitrogen starvation" RELATED [PomBase:mah] synonym: "reduced RNA level during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000826 ! decreased RNA level created_by: midori creation_date: 2012-06-14T16:52:51Z [Term] id: FYPO:0001153 name: normal cellular methylamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of methylamine measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular methylamine accumulation" RELATED [PomBase:mah] synonym: "normal cellular methylamine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-06-14T16:54:23Z [Term] id: FYPO:0001154 name: increased cellular methylamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of methylamine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular methylamine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased methylamine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-06-14T16:55:28Z [Term] id: FYPO:0001155 name: altered effect on growth medium def: "A phenotype in which the changes that take place in growth medium, due to metabolism, secretion, etc. by a cell or population of cells, differs from normal." [PomBase:mah] synonym: "abnormal effect on growth medium" EXACT [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-06-15T12:57:29Z [Term] id: FYPO:0001156 name: decreased pH of growth medium def: "A phenotype in which cells cause the pH of their growth medium to decrease by a greater amount than normal." [PomBase:mah] synonym: "decreased pH level of growth medium" EXACT [PomBase:al] synonym: "increased growth medium acidification" EXACT [PMID:10467002, PomBase:mah] is_a: FYPO:0001155 ! altered effect on growth medium created_by: midori creation_date: 2012-06-15T13:37:06Z [Term] id: FYPO:0001157 name: increased cell population growth rate at high pH def: "A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium with higher than standard pH. Standard S. pombe growth media are approximately pH 5.6." [PMID:10467002, PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "enhanced growth at high pH" RELATED [PomBase:mah] synonym: "fast cell population growth at high pH" EXACT [PomBase:mah] synonym: "increased cell population growth rate at high pH during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000636 ! increased cell population growth rate created_by: midori creation_date: 2012-06-15T13:43:25Z [Term] id: FYPO:0001158 name: normal cellular pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular pH during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular pH level" EXACT [PomBase:al] is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-06-15T13:47:22Z [Term] id: FYPO:0001159 name: increased cellular pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is higher than normal." [PomBase:mah] synonym: "increased cellular pH during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular pH level" EXACT [PomBase:al] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-06-15T13:47:43Z [Term] id: FYPO:0001160 name: cell cycle arrest in mitotic G2 phase during stationary phase def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G2 phase when the population in which the cell is found is in stationary phase." [PMID:19366728, PomBase:mah] synonym: "mitotic G2 phase arrest during stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000446 ! cell cycle arrest in mitotic G2 phase is_a: FYPO:0000563 ! abnormal mitotic G2 phase progression is_a: FYPO:0001028 ! abnormal cell cycle arrest in mitotic interphase created_by: midori creation_date: 2012-06-15T14:04:54Z [Term] id: FYPO:0001161 name: decreased aerobic cell population growth on glucose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal under aerobic conditions and in a medium containing glucose as the carbon source." [PomBase:mah] synonym: "decreased aerobic vegetative cell growth on glucose carbon source" EXACT [PomBase:mah] synonym: "decreased hypoxic growth on glucose carbon source" BROAD [PomBase:mah] synonym: "reduced aerobic cell growth on glucose carbon source" EXACT [PomBase:mah] synonym: "slow aerobic cell growth on glucose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001407 ! decreased cell population growth on glucose carbon source created_by: midori creation_date: 2012-06-15T14:18:50Z [Term] id: FYPO:0001162 name: decreased cell population growth on raffinose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal under aerobic conditions and in a medium containing raffinose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased aerobic cell growth on raffinose carbon source" NARROW [PomBase:mah] synonym: "decreased growth on raffinose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on raffinose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on raffinose carbon source" EXACT [PomBase:mah] synonym: "slow aerobic cell growth on raffinose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-06-15T14:21:23Z [Term] id: FYPO:0001163 name: decreased hypoxic cell population growth on glucose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal under semi-anaerobic conditions and in a medium containing glucose as the carbon source." [PomBase:mah] synonym: "decreased hypoxic growth on glucose carbon source" BROAD [PomBase:mah] synonym: "decreased hypoxic vegetative cell growth on glucose carbon source" EXACT [PomBase:mah] synonym: "decreased semi-anaerobic cell growth on glucose carbon source" EXACT [PomBase:al] synonym: "sensitive to hypoxia" RELATED [PomBase:community_curation] synonym: "slow semi-anaerobic cell growth on glucose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001407 ! decreased cell population growth on glucose carbon source created_by: midori creation_date: 2012-06-15T14:22:11Z [Term] id: FYPO:0001164 name: normal cell population growth on glucose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing glucose as the carbon source." [PomBase:mah] synonym: "normal growth on glucose carbon source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on dextrose carbon source" EXACT [PomBase:al] synonym: "normal vegetative cell population growth on glucose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-15T14:22:57Z [Term] id: FYPO:0001165 name: inviable cell following anaerobic growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell that is exposed to anaerobic conditions fails to grow upon being returned to aerobic conditions, and eventually dies." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "essential following anaerobic growth" RELATED [PomBase:mah] synonym: "inviable following anaerobic vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-06-15T14:28:05Z [Term] id: FYPO:0001166 name: normal cell population growth on fructose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing fructose as the carbon source." [PomBase:mah] synonym: "normal growth on fructose carbon source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on fructose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-18T14:58:12Z [Term] id: FYPO:0001167 name: abnormal ATPase activity def: "A molecular function phenotype in which the observed rate of ATPase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-06-18T15:16:22Z [Term] id: FYPO:0001168 name: decreased ATPase activity def: "A molecular function phenotype in which the observed rate of ATPase activity is decreased." [PomBase:mah] synonym: "reduced ATPase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001167 ! abnormal ATPase activity created_by: midori creation_date: 2012-06-18T15:16:30Z [Term] id: FYPO:0001169 name: normal proton transport def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which proton (H+) transport is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal hydrogen ion transport" EXACT [PomBase:mah] synonym: "normal proton transport during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-06-18T15:18:27Z [Term] id: FYPO:0001170 name: decreased methionine import during nitrogen starvation def: "A cellular process phenotype in which the import of methionine into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "decreased methionine import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased methionine transport into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased methionine uptake during nitrogen starvation" EXACT [GO:0036233] synonym: "reduced methionine import during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001558 ! decreased methionine import is_a: FYPO:0001648 ! abnormal amino acid import during nitrogen starvation created_by: midori creation_date: 2012-06-18T15:29:46Z [Term] id: FYPO:0001171 name: decreased cellular pH def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is lower than normal." [PomBase:mah] synonym: "decreased cellular pH during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular pH level" EXACT [PomBase:al] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-06-18T15:37:06Z [Term] id: FYPO:0001172 name: abnormal 7-methylguanosine cap hypermethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to form a 2,2,7-trimethylguanosine cap structure is abnormal." [PomBase:mah] synonym: "abnormal 2,2,7-trimethylguanosine cap formation" EXACT [GO:0036261, PomBase:mah] synonym: "abnormal 7-methylguanosine cap hypermethylation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal conversion of m(7)G to m(3)G" EXACT [GO:0036261, PomBase:mah] synonym: "abnormal snoRNA capping" NARROW [GO:0036261, PomBase:mah] synonym: "abnormal snRNA capping" NARROW [GO:0036261, PomBase:mah] synonym: "abnormal TMG cap formation" EXACT [GO:0036261, PomBase:mah] is_a: FYPO:0000370 ! abnormal RNA modification is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2012-06-18T15:51:40Z [Term] id: FYPO:0001173 name: abolished 7-methylguanosine cap hypermethylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to form a 2,2,7-trimethylguanosine cap structure is abolished." [PomBase:mah] synonym: "2,2,7-trimethylguanosine cap formation abolished" EXACT [GO:0036261, PomBase:mah] synonym: "7-methylguanosine cap hypermethylation abolished" EXACT [PomBase:mah] synonym: "7-methylguanosine cap hypermethylation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "conversion of m(7)G to m(3)G abolished" EXACT [GO:0036261, PomBase:mah] synonym: "snoRNA capping abolished" NARROW [GO:0036261, PomBase:mah] synonym: "snRNA capping abolished" NARROW [GO:0036261, PomBase:mah] synonym: "TMG cap formation abolished" EXACT [GO:0036261, PomBase:mah] is_a: FYPO:0000371 ! abolished RNA modification is_a: FYPO:0001172 ! abnormal 7-methylguanosine cap hypermethylation created_by: midori creation_date: 2012-06-18T15:57:19Z [Term] id: FYPO:0001174 name: normal cell population growth on sucrose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing sucrose as the carbon source." [PomBase:mah] synonym: "normal growth on sucrose carbon source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on sucrose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-21T11:11:55Z [Term] id: FYPO:0001175 name: normal cell population growth on maltose carbon source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing maltose as the carbon source." [PomBase:mah] synonym: "normal growth on maltose carbon source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on maltose carbon source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-06-21T11:12:36Z [Term] id: FYPO:0001176 name: decreased cell population growth on sucrose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing sucrose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on sucrose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on sucrose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on sucrose carbon source" RELATED [PomBase:mah] synonym: "slow cell growth on sucrose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-06-21T11:13:07Z [Term] id: FYPO:0001177 name: decreased cell population growth on trehalose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing trehalose as the carbon source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on trehalose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on trehalose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on trehalose carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on trehalose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-06-21T11:13:29Z [Term] id: FYPO:0001178 name: loss of viability in stationary phase upon nitrogen depletion def: "A cell population phenotype in which a smaller than normal proportion of the population remains viable when cells in a culture in stationary phase are deprived of nitrogen." [PomBase:mah] comment: Use this term to annotate experiments in which a culture is grown to stationary phase under nitrogen-depleted conditions, and then the number of cells viable enough to form a colony upon return to conditions supporting vegetative growth is measured and compared to wild type. synonym: "loss of viability upon nitrogen starvation" EXACT [PomBase:al] synonym: "sensitive to nitrogen starvation" RELATED [PomBase:al] is_a: FYPO:0000244 ! loss of viability upon nutrient depletion is_a: FYPO:0000245 ! loss of viability in stationary phase created_by: midori creation_date: 2012-06-27T14:04:23Z [Term] id: FYPO:0001179 name: protein localization abolished during vegetative growth def: "A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found in the vegetative growth phase of the life cycle." [PomBase:mah] comment: We recommend using one of the more specific terms instead of annotating to this term directly, if possible. If this term is used, we recommend noting which protein(s) were used in the assay. synonym: "abolished protein localization during vegetative growth" EXACT [PomBase:mah] synonym: "protein absent from specific location in cell during vegetative growth" RELATED [PomBase:mah] synonym: "protein localisation abolished during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth is_a: FYPO:0001375 ! protein localization abolished created_by: midori creation_date: 2012-06-27T15:07:09Z [Term] id: FYPO:0001180 name: increased protein tyrosine phosphorylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of tyrosine residues in one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal." [PomBase:mah] synonym: "increased peptidyl-tyrosine phosphorylation" EXACT [GO:0018108, PomBase:mah] synonym: "increased protein tyrosine phosphorylation during vegetative growth" EXACT [PomBase:mah] synonym: "increased tyrosine phosphorylation" EXACT [PomBase:al] is_a: FYPO:0001038 ! increased protein phosphorylation created_by: midori creation_date: 2012-06-27T15:32:08Z [Term] id: FYPO:0001181 name: normal maltase activity def: "A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal maltose alpha-glucosidase activity" EXACT [GO:0032450, PomBase:mah] is_a: FYPO:0001182 ! normal alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:33:02Z [Term] id: FYPO:0001182 name: normal alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-07-05T13:33:56Z [Term] id: FYPO:0001183 name: abnormal alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-07-05T13:36:08Z [Term] id: FYPO:0001184 name: abnormal maltase activity def: "A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is abnormal." [PomBase:mah] synonym: "abnormal maltose alpha-glucosidase activity" EXACT [GO:0032450, PomBase:mah] is_a: FYPO:0001183 ! abnormal alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:36:57Z [Term] id: FYPO:0001185 name: decreased alpha-glucosidase activity def: "A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is decreased." [PomBase:mah] synonym: "reduced alpha-glucosidase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001183 ! abnormal alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:38:13Z [Term] id: FYPO:0001186 name: decreased maltase activity def: "A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is decreased." [PomBase:mah] synonym: "decreased maltose alpha-glucosidase activity" EXACT [GO:0032450, PomBase:mah] synonym: "reduced maltase activity" EXACT [PomBase:mah] synonym: "reduced maltose alpha-glucosidase activity" RELATED [GO:0032450, PomBase:mah] is_a: FYPO:0001184 ! abnormal maltase activity is_a: FYPO:0001185 ! decreased alpha-glucosidase activity created_by: midori creation_date: 2012-07-05T13:38:33Z [Term] id: FYPO:0001187 name: decreased cell density in stationary phase def: "A cell population phenotype in which a population reaches stationary phase at, and maintains, a lower cell density than wild type." [PomBase:mah] synonym: "reduced cell density in stationary phase" EXACT [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype created_by: midori creation_date: 2012-07-05T14:04:36Z [Term] id: FYPO:0001188 name: sensitive to Calcofluor White def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Calcofluor White. Cells stop growing (and may die) at a concentration of Calcofluor White that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to Calcofluor White" EXACT [PomBase:mah] synonym: "sensitive to Calcofluor White during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-07-05T14:32:40Z [Term] id: FYPO:0001189 name: sensitive to cilofungin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cilofungin. Cells stop growing (and may die) at a concentration of cilofungin that allows wild type cells to grow." [PomBase:mah] comment: Cilofungin is an echinocandin antibiotic, related to echinocandin B. synonym: "hypersensitive to cilofungin" EXACT [PomBase:mah] synonym: "sensitive to cilofungin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-07-05T14:34:21Z [Term] id: FYPO:0001190 name: sensitive to cell wall-degrading enzymes alt_id: FYPO:0001191 def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more enzymes that degrades cell wall polysaccharides. Cells stop growing (and may die) at a concentration of such enzymes that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cell wall-degrading enzymes" EXACT [PomBase:mah] synonym: "sensitive to beta-1,3-glucan laminaripentaohydrolase" NARROW [PomBase:al, PomBase:mah] synonym: "sensitive to cell wall-degrading enzymes during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to lysing enzymes from Trichoderma harzianum" NARROW [PomBase:al] synonym: "sensitive to Lyticase" NARROW [PomBase:mah] synonym: "sensitive to Novozyme 234" NARROW [PomBase:mah] synonym: "sensitive to Zymolyase" NARROW [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-07-05T14:41:18Z [Term] id: FYPO:0001192 name: normal cell population growth on cell wall-degrading enzymes alt_id: FYPO:0001193 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which vegetative cell growth is normal (i.e. indistinguishable from wild type) in a medium containing one or more enzymes that degrades cell wall polysaccharides." [PomBase:mah] synonym: "normal cell population growth in presence of cell wall-degrading enzymes" EXACT [PomBase:mah] synonym: "normal cell population growth on beta-1,3-glucan laminaripentaohydrolase" NARROW [PomBase:al, PomBase:mah] synonym: "normal cell population growth on lysing enzymes from Trichoderma harzianum" NARROW [PomBase:al] synonym: "normal cell population growth on Lyticase" NARROW [PomBase:mah] synonym: "normal cell population growth on Novozyme 234" NARROW [PomBase:mah] synonym: "normal cell population growth on Zymolyase" NARROW [PomBase:mah] synonym: "normal cellular response to cell wall-degrading enzymes" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cell wall-degrading enzymes" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on cell wall-degrading enzymes" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-05T15:35:28Z [Term] id: FYPO:0001194 name: increased beta-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell is greater than normal." [PomBase:mah] synonym: "increased beta-D-glucan level" EXACT [CHEBI:28793, PomBase:mah] synonym: "increased beta-glucan accumulation" RELATED [PomBase:mah] synonym: "increased beta-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular beta-glucan level" EXACT [PomBase:mah] is_a: FYPO:0000027 ! abnormal cell wall is_a: FYPO:0001083 ! increased polysaccharide level is_a: FYPO:0001118 ! abnormal vegetative cell morphology created_by: midori creation_date: 2012-07-05T15:53:01Z [Term] id: FYPO:0001195 name: decreased galactomannan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular galactomannan level" EXACT [PomBase:mah] synonym: "decreased galactomannan accumulation" RELATED [PomBase:mah] synonym: "decreased galactomannan level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced galactomannan level" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level created_by: midori creation_date: 2012-07-05T15:54:27Z [Term] id: FYPO:0001196 name: normal alpha-glucan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal alpha-D-glucan level" EXACT [CHEBI:22385, PomBase:mah] synonym: "normal alpha-glucan accumulation" RELATED [PomBase:mah] synonym: "normal alpha-glucan level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular alpha-glucan level" EXACT [PomBase:al] is_a: FYPO:0001077 ! normal polysaccharide level created_by: midori creation_date: 2012-07-05T15:55:45Z [Term] id: FYPO:0001197 name: decreased cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased calcium accumulation" RELATED [PomBase:al] synonym: "decreased cellular calcium ion level" EXACT [PomBase:mah] synonym: "decreased cellular calcium level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cellular calcium level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-07-05T16:12:05Z [Term] id: FYPO:0001198 name: increased cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is higher than normal." [PomBase:mah] synonym: "increased calcium accumulation" RELATED [PomBase:mah] synonym: "increased cellular calcium ion level" EXACT [PomBase:mah] synonym: "increased cellular calcium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-07-05T16:13:54Z [Term] id: FYPO:0001199 name: normal cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular calcium accumulation" RELATED [PomBase:mah] synonym: "normal cellular calcium ion level" EXACT [PomBase:mah] synonym: "normal cellular calcium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-05T16:14:49Z [Term] id: FYPO:0001200 name: abnormal cellular response to calcium starvation def: "A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to calcium starvation is abnormal." [PomBase:mah] synonym: "abnormal cellular response to calcium ion starvation" EXACT [GO:0072732, PomBase:mah] synonym: "abnormal cellular response to calcium starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001339 ! abnormal cellular response to starvation during vegetative growth created_by: midori creation_date: 2012-07-05T16:38:24Z [Term] id: FYPO:0001201 name: sensitive to calcium starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium starvation." [PomBase:mah] synonym: "hypersensitive to calcium starvation" EXACT [PomBase:mah] synonym: "sensitive to calcium ion starvation" EXACT [GO:0072732, PomBase:mah] synonym: "sensitive to calcium starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress is_a: FYPO:0001200 ! abnormal cellular response to calcium starvation created_by: midori creation_date: 2012-07-05T16:43:08Z [Term] id: FYPO:0001202 name: normal cellular response to calcium starvation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to calcium starvation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to calcium ion starvation" EXACT [GO:0072732, PomBase:mah] synonym: "normal cellular response to calcium starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress created_by: midori creation_date: 2012-07-05T16:45:20Z [Term] id: FYPO:0001203 name: coflocculating cells def: "A cell population phenotype that reflects increased occurrence of coflocculation. In coflocculation, yeast cells coaggregate with cells of another species, usually bacteria." [PMID:11472912, PomBase:mah] comment: Note: coflocculation between S. pombe and E. coli is sensitive to mannose but not to glucose or galactose. Plant lectins such as HHA, GNA, NPA, or Concanavalin A (ConA) decrease but do not abolish S. pombe-E. coli coflocculation. Cations have different effects: Li+, Na+, K+, Mg2+ or Mn2+ increase coflocculation, Co2+, Zn2+ , and Ca2+ have no effect, and Cu2+ or Hg2+ completely abolish coflocculation. synonym: "co-flocculating cells" EXACT [PomBase:mah] synonym: "increased coflocculation" EXACT [PomBase:mah] is_a: FYPO:0000155 ! flocculating cells created_by: midori creation_date: 2012-07-06T15:40:35Z [Term] id: FYPO:0001204 name: mistimed mitosis def: "A cellular process phenotype in which cells enter mitosis earlier or later than normal, relative to cell size or DNA integrity checkpoint status." [PomBase:mah] synonym: "abnormal onset of mitosis" EXACT [PomBase:mah] synonym: "mistimed mitosis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000337 ! abnormal mitosis created_by: midori creation_date: 2012-07-06T16:15:36Z [Term] id: FYPO:0001205 name: abolished alpha-glucosidase activity def: "A molecular function phenotype in which alpha-glucosidase activity is absent." [PomBase:mah] synonym: "alpha-glucosidase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity created_by: midori creation_date: 2012-07-09T17:10:25Z [Term] id: FYPO:0001206 name: abolished maltase activity def: "A molecular function phenotype in which maltase activity is absent." [PomBase:mah] synonym: "abolished protease activity" EXACT [PomBase:mah] synonym: "maltase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0001184 ! abnormal maltase activity is_a: FYPO:0001205 ! abolished alpha-glucosidase activity created_by: midori creation_date: 2012-07-09T17:13:55Z [Term] id: FYPO:0001207 name: sensitive to raffinose def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to raffinose. Cells stop growing (and may die) at a concentration of raffinose that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to raffinose" EXACT [PomBase:mah] synonym: "sensitive to raffinose during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-07-12T10:30:03Z [Term] id: FYPO:0001208 name: substance absent from cell during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in a cell is too low to detect." [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001888 ! substance absent from cell created_by: midori creation_date: 2012-07-12T12:09:35Z [Term] id: FYPO:0001209 name: polysaccharide absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is too low to detect." [PomBase:mah] synonym: "polysaccharide absent from cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level is_a: FYPO:0001208 ! substance absent from cell during vegetative growth created_by: midori creation_date: 2012-07-12T12:12:20Z [Term] id: FYPO:0001210 name: Glc2Man9GlcNAc absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc2Man9GlcNAc2 measured in a cell is too low to detect. Glc2Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing two D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59082, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "absent Glc2Man9GlcNAc" EXACT [PomBase:al] synonym: "Glc2Man9GlcNAc absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "Glc2Man9GlcNAc2 absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001209 ! polysaccharide absent from cell created_by: midori creation_date: 2012-07-12T12:13:39Z [Term] id: FYPO:0001211 name: Glc3Man9GlcNAc absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc3Man9GlcNAc measured in a cell is too low to detect. Glc3Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing three D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:53019, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "absent Glc3Man9GlcNAc" EXACT [PomBase:al] synonym: "Glc3Man9GlcNAc absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "Glc3Man9GlcNAc2 absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001209 ! polysaccharide absent from cell is_a: FYPO:0001289 ! decreased phospholipid level created_by: midori creation_date: 2012-07-12T12:15:33Z [Term] id: FYPO:0001212 name: decreased Glc1Man9GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc1Man9GlcNAc2 measured in a cell is lower than normal. Glc1Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing one D-glucose residue, nine D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:59080, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "decreased cellular Glc1Man9GlcNAc level" EXACT [PomBase:al] synonym: "decreased Glc1Man9GlcNAc accumulation" RELATED [PomBase:mah] synonym: "decreased Glc1Man9GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Glc1Man9GlcNAc2 level" EXACT [PomBase:mah] synonym: "reduced Glc1Man9GlcNAc level" EXACT [PomBase:mah] is_a: FYPO:0001080 ! decreased polysaccharide level created_by: midori creation_date: 2012-07-12T12:16:24Z [Term] id: FYPO:0001213 name: increased Man8GlcNAc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is higher than normal. Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues." [CHEBI:64048, CHEBI:64052, PomBase:mah] comment: Note that these terms treat Man(n)GlcNAc and Man(n)GlcNAc2 as equivalent. The reason is that the GlcNAc2 form is attached to N-linked glycoproteins, but the GlcNAc form is what is usually detected in experiments, following cleavage by endoglycosidase H. For the purposes of observing and interpreting phenotypes, the difference is not significant. synonym: "increased cellular Man8GlcNAc level" EXACT [PomBase:al] synonym: "increased Man8GlcNAc accumulation" RELATED [PomBase:mah] synonym: "increased Man8GlcNAc level during vegetative growth" EXACT [PomBase:mah] synonym: "increased Man8GlcNAc2 level" EXACT [PomBase:mah] is_a: FYPO:0001083 ! increased polysaccharide level created_by: midori creation_date: 2012-07-12T12:17:32Z [Term] id: FYPO:0001214 name: sensitive to potassium chloride def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium chloride. Cells stop growing (and may die) at a concentration of potassium chloride that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to potassium chloride" EXACT [PomBase:mah] synonym: "sensitive to potassium chloride during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-07-12T14:21:19Z [Term] id: FYPO:0001215 name: normal protein complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of a protein complex at the cellular level is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular protein complex assembly" EXACT [GO:0043623] synonym: "normal protein complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-07-12T14:30:00Z [Term] id: FYPO:0001216 name: normal SAGA complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of a SAGA complex onto chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal SAGA complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly created_by: midori creation_date: 2012-07-12T14:32:23Z [Term] id: FYPO:0001217 name: abnormal nuclear import def: "A cellular process phenotype in which nuclear import is abnormal. Nuclear import is the directed movement of any substance out of the nucleus; import of all substances or a specific substance may be affected." [PomBase:mah] synonym: "abnormal nuclear import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000518 ! abnormal nuclear transport created_by: midori creation_date: 2012-07-12T14:39:54Z [Term] id: FYPO:0001218 name: abolished nuclear export during cellular response to nitrogen starvation def: "A cellular process phenotype in which nuclear export does not occur when the cell is subject to nitrogen starvation. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "absent nuclear export during response to nitrogen starvation" EXACT [PomBase:mah] synonym: "nuclear export during response to nitrogen starvation abolished" EXACT [PomBase:mah] synonym: "nuclear export during response to nitrogen starvation abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export in response to nitrogen starvation abolished" EXACT [PomBase:al] is_a: FYPO:0000507 ! abolished nuclear export created_by: midori creation_date: 2012-07-12T14:41:50Z [Term] id: FYPO:0001219 name: increased protein level during cellular response to nitrogen starvation def: "A cell phenotype in which the amount of protein measured in a cell during a cellular response to nitrogen starvation is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "increased protein accumulation during cellular response to nitrogen starvation" RELATED [PomBase:mah] is_a: FYPO:0000836 ! increased protein level created_by: midori creation_date: 2012-07-12T15:10:12Z [Term] id: FYPO:0001220 name: increased protein level during cellular response to pheromone def: "A cell phenotype in which the amount of protein measured in a cell during a cellular response to a pheromone is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "increased protein accumulation during cellular response to pheromone" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to pheromone during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2012-07-12T15:13:41Z [Term] id: FYPO:0001221 name: normal nucleus:cytoplasm ratio def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is in the same range as wild type (approximately 0.076-0.089)." [PMID:17998401, PomBase:mah] synonym: "normal nuclear:cytoplasmic ratio" EXACT [PomBase:mah] synonym: "normal nuclear:cytoplasmic volume ratio" EXACT [PomBase:mah] synonym: "normal nucleus:cell volume ratio" EXACT [PomBase:mah] synonym: "normal nucleus:cytoplasm ratio during vegetative growth" EXACT [PomBase:mah] synonym: "normal nucleus:cytoplasm volume ratio" EXACT [PomBase:mah] is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-07-12T15:15:47Z [Term] id: FYPO:0001222 name: binucleate def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell contains two nuclei." [PomBase:mah] synonym: "binucleate cells" EXACT [PomBase:al] synonym: "binucleate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000061 ! multinucleate created_by: midori creation_date: 2012-07-12T15:37:08Z [Term] id: FYPO:0001223 name: binucleate multiseptate cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and more than one septum. The septa are grouped together between the two nuclei." [PomBase:mah] synonym: "binucleate multiseptate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001222 ! binucleate is_a: FYPO:0001252 ! multinucleate multiseptate cell relationship: has_part FYPO:0000118 ! multiseptate relationship: has_part FYPO:0001222 ! binucleate created_by: midori creation_date: 2012-07-12T15:39:43Z [Term] id: FYPO:0001224 name: binucleate monoseptate cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and one septum." [PomBase:mah] synonym: "binucleate monoseptate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001222 ! binucleate is_a: FYPO:0001225 ! monoseptate relationship: has_part FYPO:0001222 ! binucleate relationship: has_part FYPO:0001225 ! monoseptate created_by: midori creation_date: 2012-07-12T15:40:42Z [Term] id: FYPO:0001225 name: monoseptate def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single septum." [PomBase:mah] synonym: "monoseptate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-07-12T15:42:41Z [Term] id: FYPO:0001226 name: mononucleate with mislocalized septum def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single nucleus and an asymmetrically located septum." [PomBase:mah] synonym: "mononucleate with abnormal septum location" EXACT [PomBase:mah] synonym: "mononucleate with abnormal septum position" EXACT [PomBase:mah] synonym: "mononucleate with asymmetric septum" EXACT [PomBase:mah] synonym: "mononucleate with asymmetrically located septum" EXACT [PomBase:mah] synonym: "mononucleate with mislocalised septum" EXACT [PomBase:mah] synonym: "mononucleate with mislocalized septum during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000339 ! mislocalized septum is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth is_a: FYPO:0002000 ! septated mononucleate cell relationship: has_part FYPO:0000060 ! mononucleate relationship: has_part FYPO:0000339 ! mislocalized septum created_by: midori creation_date: 2012-07-12T15:44:34Z [Term] id: FYPO:0001227 name: protein mislocalized to cytoplasm during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there, during a cellular response to hydrogen peroxide." [PomBase:mah] comment: Note that this term can be used to annotate any case where a protein is found in the cytoplasm in a mutant, but not in wild type. In some cases, there may be enough additional information to annotate to 'abnormal protein localization' (FYPO:0000443) or one of its descendants. synonym: "protein mislocalised to cytoplasm during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "protein mislocalized to cytoplasm in response to hydrogen peroxide" EXACT [PomBase:al] is_a: FYPO:0000783 ! protein mislocalized to cytoplasm created_by: midori creation_date: 2012-07-13T16:15:07Z [Term] id: FYPO:0001228 name: nuclear protein accumulation during cellular response to hydrogen peroxide def: "A localization phenotype observed in the vegetative growth phase of the life cycle in which specific proteins abnormally accumulate, and are constitutively located in, the nucleus during a cellular response to hydrogen peroxide." [PomBase:mah] synonym: "nuclear accumulation of protein during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "nuclear protein accumulation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear protein accumulation in response to hydrogen peroxide" EXACT [PomBase:al] is_a: FYPO:0000255 ! nuclear protein accumulation created_by: midori creation_date: 2012-07-13T16:39:13Z [Term] id: FYPO:0001229 name: abnormal cell cortex morphology def: "A cellular structure phenotype in which the morphology of all or part of the cell cortex is abnormal. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. is_a: FYPO:0000287 ! abnormal subcellular structure created_by: midori creation_date: 2012-07-16T13:51:27Z [Term] id: FYPO:0001230 name: abnormal cell cortex morphology during nitrogen starvation def: "A cellular structure phenotype in which the morphology of all or part of the cell cortex is abnormal when the cell is subject to nitrogen starvation. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. is_a: FYPO:0001229 ! abnormal cell cortex morphology created_by: midori creation_date: 2012-07-16T13:52:15Z [Term] id: FYPO:0001231 name: normal cell cortex morphology def: "A cellular structure phenotype in which the morphology of all or part of the cell cortex is normal (i.e. indistinguishable from wild type). The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. subset: qc_do_not_manually_annotate is_a: FYPO:0001233 ! normal subcellular structure created_by: midori creation_date: 2012-07-16T13:54:21Z [Term] id: FYPO:0001232 name: normal cell cortex morphology during nitrogen starvation def: "A cellular structure phenotype in which the morphology of all or part of the cell cortex is normal when the cell is subject to nitrogen starvation. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] comment: Note that an abnormal cell cortex organization process may, but does not necessarily, result in abnormal cell cortex morphology. is_a: FYPO:0001231 ! normal cell cortex morphology created_by: midori creation_date: 2012-07-16T13:56:11Z [Term] id: FYPO:0001233 name: normal subcellular structure def: "A cell phenotype in which the amount, distribution, or morphology of a cell part is normal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal cellular pH level" EXACT [PomBase:al] is_a: FYPO:0000136 ! cellular structure phenotype is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-07-16T13:59:40Z [Term] id: FYPO:0001234 name: slow vegetative cell population growth def: "A cell population phenotype in which vegetative cell population growth is slower than normal." [PomBase:mah] comment: Use this term when growth rate, e.g. as measured by population doubling time, is reduced. Note that with growth on plates, growth rate can be difficult to assess, so it may be better to use 'decreased cell growth' (FYPO:0000046). Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased vegetative cell population growth rate" EXACT [PomBase:mah] synonym: "growth defect, slow growth" BROAD [PomBase:mah] synonym: "reduced vegetative cell population growth rate" EXACT [PomBase:mah] is_a: FYPO:0001356 ! abnormal vegetative cell population growth created_by: midori creation_date: 2012-07-16T14:20:51Z [Term] id: FYPO:0001235 name: decreased extent of cell population growth def: "A cellular process phenotype in which cell growth in a cell population occurs to a lower extent than normal, i.e. the population stops growing earlier than normal." [PomBase:mah] is_a: FYPO:0000003 ! cell population phenotype is_a: FYPO:0001985 ! abnormal phenotype relationship: has_part FYPO:0000046 ! decreased cell population growth created_by: midori creation_date: 2012-07-16T14:25:09Z [Term] id: FYPO:0001236 name: normal cell population growth on cycloheximide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cycloheximide." [PomBase:mah] synonym: "normal cell population growth in presence of cycloheximide" EXACT [PomBase:mah] synonym: "normal cellular response to cycloheximide" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cycloheximide" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on cycloheximide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:25:03Z [Term] id: FYPO:0001237 name: normal cell population growth on cadmium def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cadmium ions." [PomBase:mah] synonym: "normal cell population growth in presence of cadmium" EXACT [PomBase:mah] synonym: "normal cell population growth on cadmium ion" EXACT [PomBase:mah] synonym: "normal cellular response to cadmium" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cadmium" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on cadmium" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:25:47Z [Term] id: FYPO:0001238 name: normal cell population growth on staurosporine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing staurosporine." [PomBase:mah] synonym: "normal cell population growth in presence of staurosporine" EXACT [PomBase:mah] synonym: "normal cellular response to staurosporine" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on staurosporine" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on staurosporine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:27:03Z [Term] id: FYPO:0001239 name: normal cell population growth on t-BOOH def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tert-butyl hydroperoxide (t-BOOH)." [PomBase:mah] synonym: "normal cell population growth in presence of t-BOOH" EXACT [PomBase:mah] synonym: "normal cell population growth on 2-methyl-prop-2-yl-hydroperoxide" EXACT [CHEBI:365419] synonym: "normal cell population growth on tert-butyl hydroperoxide" EXACT [PomBase:mah] synonym: "normal cellular response to t-BOOH" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on t-BOOH" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on t-BOOH" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:28:00Z [Term] id: FYPO:0001240 name: normal cell population growth on diamide def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide, also known as diamide." [PomBase:mah] synonym: "normal cell population growth in presence of diamide" EXACT [PomBase:mah] synonym: "normal cell population growth on N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide" EXACT [CHEBI:48958, PomBase:mah] synonym: "normal cellular response to diamide" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on diamide" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on diamide" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:30:45Z [Term] id: FYPO:0001241 name: normal cell population growth on anisomycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing anisomycin." [PomBase:mah] synonym: "normal cell population growth in presence of anisomycin" EXACT [PomBase:mah] synonym: "normal cellular response to anisomycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on anisomycin" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on anisomycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-07-16T15:31:50Z [Term] id: FYPO:0001242 name: increased RNA level during cellular response to adenine starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to adenine starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mRNA level during cellular response to adenine starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to adenine starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to adenine starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-07-16T15:56:42Z [Term] id: FYPO:0001243 name: increased RNA level during cellular response to vitamin B1 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to vitamin B1 is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mRNA level during cellular response to vitamin B1" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to vitamin B1" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to thiamine" EXACT [GO:0071301, PomBase:mah] synonym: "increased RNA level during cellular response to vitamin B1 during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-07-16T15:57:59Z [Term] id: FYPO:0001244 name: decreased RNA level during cellular response to vitamin B1 starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to vitamin B1 starvation is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased mRNA level during cellular response to vitamin B1 starvation" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to vitamin B1 starvation" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to thiamine starvation" EXACT [GO:0036225, PomBase:mah] synonym: "decreased RNA level during cellular response to vitamin B1 starvation during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA level during cellular response to vitamin B1 starvation" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-07-16T16:01:16Z [Term] id: FYPO:0001245 name: sensitive to cobalt def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cobalt ions." [PomBase:mah] synonym: "hypersensitive to cobalt" EXACT [PomBase:mah] synonym: "sensitive to cobalt during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to cobalt ions" EXACT [CHEBI:23336] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-07-16T16:15:13Z [Term] id: FYPO:0001246 name: normal RNA level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal mRNA level during cellular response to hydrogen peroxide" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to hydrogen peroxide" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-07-17T13:17:07Z [Term] id: FYPO:0001248 name: abnormal regulation of DNA replication initiation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the initiation of DNA-dependent DNA replication is abnormal." [PomBase:mah] synonym: "abnormal regulation of DNA replication initiation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal regulation of DNA-dependent DNA replication initiation" EXACT [GO:0006270, PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-07-17T13:25:25Z [Term] id: FYPO:0001249 name: increased origin firing efficiency def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin is higher than in wild type. In cells with increased origin firing efficiency, genomic DNA replication initiates from more origins than wild type, and is completed in more, smaller segments, than wild type." [PMID:18799612, PomBase:mah] synonym: "increased origin firing efficiency during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of DNA replication initiation created_by: midori creation_date: 2012-07-17T13:28:55Z [Term] id: FYPO:0001250 name: decreased origin firing efficiency def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin is lower than in wild type. In cells with decreased origin firing efficiency, genomic DNA replication initiates from fewer origins than wild type, and is completed in fewer, larger segments, than wild type." [PMID:18799612, PomBase:mah] synonym: "decreased origin firing efficiency during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001248 ! abnormal regulation of DNA replication initiation created_by: midori creation_date: 2012-07-17T13:31:48Z [Term] id: FYPO:0001252 name: multinucleate multiseptate cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two or more nuclei and more than one septum per cell." [PomBase:mah] synonym: "multinucleate multiseptate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000061 ! multinucleate is_a: FYPO:0000118 ! multiseptate relationship: has_part FYPO:0000061 ! multinucleate relationship: has_part FYPO:0000118 ! multiseptate created_by: midori creation_date: 2012-07-19T15:38:21Z [Term] id: FYPO:0001253 name: multinucleate multiseptate cell, septa between nuclei def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two or more nuclei and more than one septum, and the septa are located so as to form separate compartments with a single nucleus in each." [PomBase:mah] synonym: "multinucleate multiseptate cell, septa between nuclei during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001252 ! multinucleate multiseptate cell created_by: midori creation_date: 2012-07-19T15:40:18Z [Term] id: FYPO:0001254 name: multinucleate multiseptate cell, septa grouped def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two or more nuclei and more than one septum, and the septa are grouped together between two compartments, one or more of which may contain multiple nuclei." [PomBase:mah] synonym: "multinucleate multiseptate cell, septa grouped during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002002 ! multiseptate cell, septa grouped created_by: midori creation_date: 2012-07-19T15:41:59Z [Term] id: FYPO:0001255 name: increased protein level during cellular response to oxygen def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to the level of oxygen is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "increased protein accumulation during cellular response to oxygen" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to oxygen during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to oxygen levels" EXACT [GO:0071453] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2012-07-19T16:01:11Z [Term] id: FYPO:0001256 name: increased protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "increased protein accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "increased protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to increased oxygen tension" EXACT [GO:0071456] is_a: FYPO:0001255 ! increased protein level during cellular response to oxygen is_a: FYPO:0001549 ! altered protein level during cellular response to hypoxia created_by: midori creation_date: 2012-07-19T16:03:44Z [Term] id: FYPO:0001257 name: normal protein level during cellular response to oxygen def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to the level of oxygen is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "normal protein accumulation during cellular response to oxygen" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to oxygen during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to oxygen levels" EXACT [GO:0071453] is_a: FYPO:0000833 ! normal protein level created_by: midori creation_date: 2012-07-19T16:05:22Z [Term] id: FYPO:0001258 name: normal protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "normal protein accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "normal protein level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "normal protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "normal protein level during cellular response to increased oxygen tension" EXACT [GO:0071456] is_a: FYPO:0001257 ! normal protein level during cellular response to oxygen created_by: midori creation_date: 2012-07-19T16:06:01Z [Term] id: FYPO:0001259 name: decreased RNA level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased protein level during cellular response to increased oxygen tension" EXACT [GO:0071456] synonym: "decreased RNA accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "decreased RNA level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-07-19T16:07:22Z [Term] id: FYPO:0001260 name: normal RNA level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal mRNA level during cellular response to hypoxia" NARROW [PomBase:mah] synonym: "normal protein level during cellular response to increased oxygen tension" EXACT [GO:0071456] synonym: "normal RNA accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "normal RNA level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-07-19T16:10:05Z [Term] id: FYPO:0001261 name: decreased cytokinesis during cellular hyperosmotic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cell cycle cytokinesis is decreased during a cellular hyperosmotic response." [PomBase:mah] synonym: "decreased cytokinesis during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] synonym: "reduced cytokinesis during cellular hyperosmotic response" EXACT [PomBase:mah] is_a: FYPO:0000418 ! decreased cytokinesis created_by: midori creation_date: 2012-07-19T16:20:14Z [Term] id: FYPO:0001262 name: stubby cell during cellular hyperosmotic response def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which the cell diameter is larger than normal and the cell length is shorter than normal, during a cellular hyperosmotic response." [PomBase:mah] synonym: "stubby cell during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000024 ! stubby cell created_by: midori creation_date: 2012-07-19T16:21:16Z [Term] id: FYPO:0001263 name: branched cell during cellular hyperosmotic response def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched during a cellular hyperosmotic response. In branched cells, a daughter cell grows from near, and at approximately a right angle to, the septum of the mother cell, resulting in the formation of a branched, septated cell. Cell division may give rise to branched or unbranched daughter cells." [PomBase:jh, PomBase:mah] synonym: "branched cell during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000015 ! branched cell created_by: midori creation_date: 2012-07-19T16:22:02Z [Term] id: FYPO:0001264 name: abnormal cell polarity during cellular hyperosmotic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is abnormal during a cellular hyperosmotic response." [PomBase:mah] synonym: "abnormal cell polarity during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal establishment or maintenance of cell polarity during cellular hyperosmotic response" EXACT [PomBase:mah] synonym: "cell polarity defects during cellular hyperosmotic response" EXACT [PomBase:mah] is_a: FYPO:0000026 ! abnormal cell polarity created_by: midori creation_date: 2012-07-19T16:23:32Z [Term] id: FYPO:0001265 name: increased protein phosphorylation during cellular hyperosmotic response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular hyperosmotic response." [PomBase:mah] synonym: "increased protein phosphorylation during cellular hyperosmotic response during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001038 ! increased protein phosphorylation created_by: midori creation_date: 2012-07-19T16:27:02Z [Term] id: FYPO:0001266 name: normal protein phosphorylation during cellular response to salt stress def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal during a cellular response to salt stress." [PomBase:mah] comment: When using this term, it is recommended to note the specific protein(s) affected. synonym: "normal protein phosphorylation during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation created_by: midori creation_date: 2012-07-19T16:28:13Z [Term] id: FYPO:0001267 name: abolished nuclear export during cellular hypotonic salinity response def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export does not occur when the cell is subject to a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected." [PomBase:mah] synonym: "absent nuclear export during cellular hypotonic salinity response" EXACT [PomBase:mah] synonym: "nuclear export during cellular hypotonic salinity response abolished" EXACT [PomBase:mah] synonym: "nuclear export during cellular hypotonic salinity response abolished during vegetative growth" EXACT [PomBase:mah] synonym: "nuclear export in response to salt starvation abolished" EXACT [PomBase:al] is_a: FYPO:0000507 ! abolished nuclear export created_by: midori creation_date: 2012-07-19T16:50:01Z [Term] id: FYPO:0001268 name: abnormal protein localization to kinetochore def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the centromere and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to kinetochore" EXACT [PomBase:mah] synonym: "abnormal protein localization to chromosome, centric region" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to chromosome, centromeric region" EXACT [GO:0071459, PomBase:mah] synonym: "abnormal protein localization to kinetochore during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-07-19T16:53:31Z [Term] id: FYPO:0001269 name: abolished protein localization to kinetochore def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to kinetochore" EXACT [PomBase:mah] synonym: "abolished protein localization to kinetochore during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to kinetochore abolished" EXACT [PomBase:mah] is_a: FYPO:0001179 ! protein localization abolished during vegetative growth is_a: FYPO:0001268 ! abnormal protein localization to kinetochore created_by: midori creation_date: 2012-07-19T16:54:02Z [Term] id: FYPO:0001270 name: complete but unequal mitotic sister chromatid separation def: "A cellular process phenotype in which mitotic sister chromatid separation results in the separation of chromosomes into two distinct unequal masses, located at or near the ends of an elongated mitotic spindle." [PMID:22711988, PomBase:mah] synonym: "complete but unequal mitotic chromosome separation" EXACT [PomBase:mah] synonym: "complete but unequal mitotic sister chromatid segregation" RELATED [PomBase:mah] synonym: "complete but unequal mitotic sister chromatid separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic chromosome separation created_by: midori creation_date: 2012-07-19T17:05:51Z [Term] id: FYPO:0001271 name: incomplete, unequal mitotic sister chromatid separation def: "A cellular process phenotype in which mitotic sister chromatid separation stops before completing separation of chromosomes; some, but not all, DNA may be moved towards the ends of an elongated mitotic spindle. Chromosomes do not segregate into two equal masses." [PMID:22711988, PomBase:mah] synonym: "incomplete, unequal mitotic chromosome separation" EXACT [PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid segregation" RELATED [PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid separation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000670 ! abnormal mitotic chromosome separation created_by: midori creation_date: 2012-07-19T17:09:10Z [Term] id: FYPO:0001272 name: incomplete, unequal mitotic sister chromatid separation, with smeared DNA def: "A cellular process phenotype in which mitotic sister chromatid separation stops before completing separation of chromosomes, and DNA becomes spread into an indistinct mass along much of the length of the mitotic spindle." [PMID:22711988, PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid segregation, with smeared DNA" RELATED [PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid separation, with smeared DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001271 ! incomplete, unequal mitotic sister chromatid separation created_by: midori creation_date: 2012-07-19T17:15:07Z [Term] id: FYPO:0001273 name: incomplete, unequal mitotic sister chromatid separation, with unseparated DNA def: "A cellular process phenotype in which mitotic sister chromatid separation stops before completing separation of chromosomes, and DNA remains in a single mass at or near the midpoint of the mitotic spindle." [PMID:22711988, PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid segregation, with unseparated DNA" RELATED [PomBase:mah] synonym: "incomplete, unequal mitotic sister chromatid separation, with unseparated DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001271 ! incomplete, unequal mitotic sister chromatid separation created_by: midori creation_date: 2012-07-19T17:15:33Z [Term] id: FYPO:0001274 name: decreased protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "decreased protein accumulation during cellular response to hypoxia" RELATED [PomBase:mah] synonym: "decreased protein level during cellular response to hyperoxic stress" EXACT [GO:0071456] synonym: "decreased protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] synonym: "decreased protein level during cellular response to increased oxygen tension" EXACT [GO:0071456] synonym: "reduced protein level during cellular response to hypoxia" EXACT [PomBase:mah] is_a: FYPO:0001324 ! decreased protein level during vegetative growth is_a: FYPO:0001549 ! altered protein level during cellular response to hypoxia created_by: midori creation_date: 2012-07-19T17:21:36Z [Term] id: FYPO:0001275 name: decreased protein binding during cellular response to hypoxia def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to hypoxia." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein binding in response to hypoxia" RELATED [PomBase:al] synonym: "decreased protein-protein interaction during cellular response to hypoxia" EXACT [PomBase:mah] is_a: FYPO:0001645 ! decreased protein binding created_by: midori creation_date: 2012-07-19T17:23:30Z [Term] id: FYPO:0001276 name: decreased MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of MCM complex assembly is decreased." [PomBase:mah] synonym: "decreased MCM complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "reduced MCM complex assembly" EXACT [PomBase:mah] is_a: FYPO:0000448 ! abnormal MCM complex assembly created_by: midori creation_date: 2012-07-20T17:32:31Z [Term] id: FYPO:0001277 name: abolished MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is abolished." [PomBase:mah] synonym: "abolished MCM complex assembly during vegetative growth" EXACT [PomBase:mah] synonym: "MCM complex assembly abolished" EXACT [PomBase:mah] is_a: FYPO:0000448 ! abnormal MCM complex assembly created_by: midori creation_date: 2012-07-20T17:34:14Z [Term] id: FYPO:0001278 name: normal MCM complex assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal MCM complex assembly during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001215 ! normal protein complex assembly created_by: midori creation_date: 2012-07-20T17:36:38Z [Term] id: FYPO:0001279 name: increased RNA level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to oxidative stress is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mRNA level during cellular response to oxidative stress" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to DEM" NARROW [PomBase:al] synonym: "increased RNA level during cellular response to diethyl maleate" NARROW [PomBase:mah] synonym: "increased RNA level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-07-26T10:59:25Z [Term] id: FYPO:0001280 name: decreased RNA level during cellular response to oxidative stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to oxidative stress is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased mRNA level during cellular response to oxidative stress" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to oxidative stress" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to DEM" NARROW [PomBase:al] synonym: "decreased RNA level during cellular response to diethyl maleate" NARROW [PomBase:mah] synonym: "decreased RNA level during cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] synonym: "reduced RNA level during cellular response to oxidative stress" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-07-26T11:06:41Z [Term] id: FYPO:0001281 name: normal protein phosphorylation during cellular response to hydrogen peroxide def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal during a cellular response to hydrogen peroxide." [PomBase:mah] comment: When using this term, it is recommended to note the specific protein(s) affected. synonym: "normal protein phosphorylation during cellular response to H2O2" EXACT [PomBase:mah] synonym: "normal protein phosphorylation during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000776 ! normal protein phosphorylation created_by: midori creation_date: 2012-07-26T11:15:18Z [Term] id: FYPO:0001282 name: abnormal chromatin organization during nitrogen starvation def: "A cellular process phenotype in which any process of chromatin organization is abnormal when the cell is subject to nitrogen starvation. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PomBase:mah] synonym: "abnormal chromatin organisation during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000642 ! abnormal chromatin organization created_by: midori creation_date: 2012-07-26T11:50:10Z [Term] id: FYPO:0001283 name: decreased protein level during cellular response to nitrogen starvation def: "A cell phenotype in which the amount of protein measured in a cell during a cellular response to nitrogen starvation is lower than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "decreased protein accumulation during cellular response to nitrogen starvation" RELATED [PomBase:mah] synonym: "reduced protein level during cellular response to nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2012-07-26T11:59:16Z [Term] id: FYPO:0001284 name: phosphatidylserine absent from cell def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is too low to detect." [PomBase:mah] synonym: "phosphatidyl-L-serine absent from cell" EXACT [CHEBI:18303] synonym: "phosphatidylserine absent from cell during vegetative growth" EXACT [PomBase:mah] synonym: "PS absent from cell" EXACT [PomBase:mah] is_a: FYPO:0001208 ! substance absent from cell during vegetative growth is_a: FYPO:0001289 ! decreased phospholipid level created_by: midori creation_date: 2012-07-26T12:20:15Z [Term] id: FYPO:0001285 name: decreased cellular phosphatidylethanolamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular PE level" EXACT [PomBase:mah] synonym: "decreased cellular phosphatidylethanolamine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased phosphatidylethanolamine accumulation" RELATED [PomBase:al] synonym: "reduced cellular phosphatidylethanolamine level" EXACT [PomBase:mah] is_a: FYPO:0001289 ! decreased phospholipid level created_by: midori creation_date: 2012-07-26T12:25:19Z [Term] id: FYPO:0001286 name: increased cellular phosphoinositide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell is higher than normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." [PomBase:mah] synonym: "increased cellular phosphoinositide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PI level" RELATED [PomBase:al] synonym: "increased PI accumulation" RELATED [PomBase:al] is_a: FYPO:0001288 ! increased phospholipid level is_a: FYPO:0001290 ! altered cellular phosphoinositide level created_by: midori creation_date: 2012-07-26T12:26:35Z [Term] id: FYPO:0001287 name: altered phospholipid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell differs from normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester." [CHEBI:16247, PomBase:mah] synonym: "abnormal phospholipid level" EXACT [PomBase:mah] synonym: "altered cellular phospholipid level" EXACT [PomBase:mah] synonym: "altered phospholipid level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-26T13:16:37Z [Term] id: FYPO:0001288 name: increased phospholipid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell is higher than normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester." [CHEBI:16247, PomBase:mah] synonym: "increased cellular phospholipid level" EXACT [PomBase:mah] synonym: "increased phospholipid accumulation" RELATED [PomBase:mah] synonym: "increased phospholipid level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001287 ! altered phospholipid level is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-26T13:21:43Z [Term] id: FYPO:0001289 name: decreased phospholipid level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell is lower than normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester." [CHEBI:16247, PomBase:mah] synonym: "decreased cellular phospholipid level" EXACT [PomBase:mah] synonym: "decreased phospholipid accumulation" RELATED [PomBase:mah] synonym: "decreased phospholipid level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced phospholipid level" EXACT [PomBase:mah] is_a: FYPO:0001287 ! altered phospholipid level is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-07-26T13:22:15Z [Term] id: FYPO:0001290 name: altered cellular phosphoinositide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell differs from normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." [PomBase:mah] synonym: "abnormal cellular phosphoinositide level" EXACT [PomBase:mah] synonym: "altered cellular phosphoinositide level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular PI level" RELATED [PomBase:al] synonym: "altered PI accumulation" RELATED [PomBase:al] is_a: FYPO:0001287 ! altered phospholipid level created_by: midori creation_date: 2012-07-26T13:23:26Z [Term] id: FYPO:0001291 name: abnormal CDP-diacylglycerol-serine O-phosphatidyltransferase activity def: "A molecular function phenotype in which the observed rate of CDP-diacylglycerol-serine O-phosphatidyltransferase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-07-26T13:33:37Z [Term] id: FYPO:0001292 name: decreased CDP-diacylglycerol-serine O-phosphatidyltransferase activity def: "A molecular function phenotype in which the observed rate of CDP-diacylglycerol-serine O-phosphatidyltransferase activity is decreased." [PomBase:mah] synonym: "reduced CDP-diacylglycerol-serine O-phosphatidyltransferase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001291 ! abnormal CDP-diacylglycerol-serine O-phosphatidyltransferase activity created_by: midori creation_date: 2012-07-26T13:34:04Z [Term] id: FYPO:0001293 name: normal cell wall biogenesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell wall biogenesis is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cell wall biogenesis during vegetative growth" EXACT [PomBase:mah] synonym: "normal fungal-type cell wall biogenesis" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-07-26T13:49:47Z [Term] id: FYPO:0001294 name: normal actin cortical patch localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actin cortical patch localisation" EXACT [PomBase:mah] synonym: "normal actin cortical patch localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2012-07-26T14:12:03Z [Term] id: FYPO:0001295 name: normal palmitoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-07-26T14:25:18Z [Term] id: FYPO:0001296 name: normal oleoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal oleoyl-CoA synthetase activity" EXACT [GO:0090434, PomBase:mah] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-07-26T14:31:43Z [Term] id: FYPO:0001297 name: abnormal palmitoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:33:36Z [Term] id: FYPO:0001298 name: decreased palmitoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] synonym: "reduced palmitoyl-CoA ligase activity" EXACT [PomBase:al] is_a: FYPO:0001297 ! abnormal palmitoyl-CoA ligase activity is_a: FYPO:0001307 ! decreased long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:34:05Z [Term] id: FYPO:0001299 name: abolished palmitoyl-CoA ligase activity def: "A molecular function phenotype in which palmitoyl-CoA ligase activity is absent." [PomBase:mah] synonym: "abolished palmitoyl-CoA synthetase activity" EXACT [GO:0090433, PomBase:mah] synonym: "palmitoyl-CoA ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0001297 ! abnormal palmitoyl-CoA ligase activity is_a: FYPO:0001306 ! abolished long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:34:26Z [Term] id: FYPO:0001300 name: abnormal oleoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal oleoyl-CoA synthetase activity" EXACT [GO:0090434, PomBase:mah] is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:38:21Z [Term] id: FYPO:0001301 name: abolished oleoyl-CoA ligase activity def: "A molecular function phenotype in which oleoyl-CoA ligase activity is absent." [PomBase:mah] synonym: "abolished oleoyl-CoA synthetase activity" EXACT [GO:0090434, PomBase:mah] synonym: "oleoyl-CoA ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0001300 ! abnormal oleoyl-CoA ligase activity is_a: FYPO:0001306 ! abolished long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:38:28Z [Term] id: FYPO:0001302 name: decreased oleoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased oleoyl-CoA synthetase activity" RELATED [GO:0090434, PomBase:mah] synonym: "reduced oleoyl-CoA ligase activity" EXACT [PomBase:al] is_a: FYPO:0001300 ! abnormal oleoyl-CoA ligase activity is_a: FYPO:0001307 ! decreased long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:38:38Z [Term] id: FYPO:0001303 name: abnormal myristoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of myristoyl-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal myristoyl-CoA synthetase activity" EXACT [GO:0090432, PomBase:mah] is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:40:40Z [Term] id: FYPO:0001304 name: decreased myristoyl-CoA ligase activity def: "A molecular function phenotype in which the observed rate of myristoyl-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased myristoyl-CoA synthetase activity" RELATED [GO:0090432, PomBase:mah] synonym: "reduced myristoyl-CoA ligase activity" EXACT [PomBase:al] is_a: FYPO:0001303 ! abnormal myristoyl-CoA ligase activity is_a: FYPO:0001307 ! decreased long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:40:44Z [Term] id: FYPO:0001305 name: abnormal long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which the observed rate of any long-chain fatty acid-CoA ligase activity is abnormal." [PomBase:mah] synonym: "abnormal lcfa-ligase activity" EXACT [PomBase:al] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-07-26T14:44:02Z [Term] id: FYPO:0001306 name: abolished long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which long-chain fatty acid-CoA ligase activity is absent." [PomBase:mah] synonym: "abolished lcfa-ligase activity" EXACT [PomBase:al] synonym: "long-chain fatty acid-CoA ligase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:45:16Z [Term] id: FYPO:0001307 name: decreased long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which the observed rate of long-chain fatty acid-CoA ligase activity is decreased." [PomBase:mah] synonym: "decreased lcfa-ligase activity" EXACT [PomBase:al] synonym: "reduced long-chain fatty acid-CoA ligase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:45:21Z [Term] id: FYPO:0001308 name: increased long-chain fatty acid-CoA ligase activity def: "A molecular function phenotype in which the observed rate of long-chain fatty acid-CoA ligase activity is increased." [PomBase:mah] synonym: "increased lcfa-ligase activity" EXACT [PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001305 ! abnormal long-chain fatty acid-CoA ligase activity created_by: midori creation_date: 2012-07-26T14:45:26Z [Term] id: FYPO:0001309 name: increased viability in stationary phase def: "A cell population phenotype in which a larger than normal proportion of the population remains viable after entering stationary phase." [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2012-07-26T14:58:27Z [Term] id: FYPO:0001310 name: normal viability in stationary phase def: "A cell population phenotype in which a normal proportion of the population remains viable after entering stationary phase." [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype is_a: FYPO:0002057 ! cell population viability created_by: midori creation_date: 2012-07-26T14:59:20Z [Term] id: FYPO:0001311 name: decreased plasmid loss def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which plasmids are lost at a lower frequency than normal. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation." [PomBase:mah] synonym: "decreased plasmid loss during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-07-26T15:11:43Z [Term] id: FYPO:0001312 name: normal vegetative phenotype def: "A normal phenotype that is observed when cells are in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast normal vegetative phenotype" EXACT [PomBase:mah] is_a: FYPO:0000257 ! normal phenotype created_by: midori creation_date: 2012-08-01T11:18:45Z [Term] id: FYPO:0001313 name: normal subcellular structure during vegetative growth def: "A cell phenotype in which the amount, distribution, or morphology of a cell part is normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0001233 ! normal subcellular structure is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T12:32:26Z [Term] id: FYPO:0001314 name: normal cell cortex morphology during vegetative growth def: "A cellular structure phenotype in which the morphology of all or part of the cell cortex is normal when the cell is in the vegetative growth phase of the life cycle. The cell cortex is the region of a cell that lies just beneath the plasma membrane." [GO:0005938, PomBase:mah] is_a: FYPO:0001231 ! normal cell cortex morphology is_a: FYPO:0001313 ! normal subcellular structure during vegetative growth created_by: midori creation_date: 2012-08-01T12:33:02Z [Term] id: FYPO:0001315 name: normal cell morphology during vegetative growth def: "A cell phenotype characterized by normal cell morphology when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000672 ! normal cell morphology is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T13:09:00Z [Term] id: FYPO:0001316 name: normal level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell is normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0001076 ! normal level of substance in cell is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T13:14:57Z [Term] id: FYPO:0001317 name: normal RNA level during vegetative growth def: "A cell phenotype in which the amount of RNA measured in a cell is normal when the cell is in the vegetative growth phase of the life cycle. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal cellular RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "normal mRNA level during vegetative growth" NARROW [PomBase:mah] is_a: FYPO:0000840 ! normal RNA level is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T13:15:43Z [Term] id: FYPO:0001318 name: normal cellular response to chemical stimulus during vegetative growth def: "A cellular response phenotype in which the cellular response to a chemical stimulus is normal in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000953 ! normal cellular response to chemical stimulus is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T13:37:42Z [Term] id: FYPO:0001319 name: normal cellular process during vegetative growth def: "A phenotype in which a specific cellular process is normal in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0001312 ! normal vegetative phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T13:42:47Z [Term] id: FYPO:0001320 name: vegetative cell phenotype def: "A phenotype that is observed at the level of an individual cell, when the cell is in the vegetative growth phase of the cell cycle." [PomBase:mah] synonym: "cell phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast vegetative cell phenotype" EXACT [PomBase:mah] synonym: "vegetative cell phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000002 ! cell phenotype created_by: midori creation_date: 2012-08-01T13:52:18Z [Term] id: FYPO:0001321 name: cellular structure phenotype during vegetative growth def: "A phenotype that affects the structure of a cell or a cellular component in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast cellular structure phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000136 ! cellular structure phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T14:44:55Z [Term] id: FYPO:0001322 name: abnormal subcellular structure during vegetative growth def: "A cellular structure phenotype in which the amount, distribution, or morphology of a cell part is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000287 ! abnormal subcellular structure is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T14:46:27Z [Term] id: FYPO:0001323 name: altered level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal level of substance in cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T14:57:41Z [Term] id: FYPO:0001324 name: decreased protein level during vegetative growth def: "A cell phenotype in which the amount of protein measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "decreased protein accumulation during vegetative growth" RELATED [PomBase:mah] synonym: "reduced protein level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level is_a: FYPO:0001325 ! altered protein level during vegetative growth is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T15:37:56Z [Term] id: FYPO:0001325 name: altered protein level during vegetative growth def: "A cell phenotype in which the amount of protein measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "abnormal protein level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular protein level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000834 ! altered protein level is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T15:11:16Z [Term] id: FYPO:0001326 name: altered RNA level during vegetative growth def: "A cell phenotype in which the amount of RNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "abnormal RNA level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular mRNA level during vegetative growth" NARROW [PomBase:vw] synonym: "altered cellular RNA level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000824 ! altered RNA level is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T15:11:33Z [Term] id: FYPO:0001327 name: increased protein level during vegetative growth def: "A cell phenotype in which the amount of protein measured in a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "increased protein accumulation during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000836 ! increased protein level is_a: FYPO:0001325 ! altered protein level during vegetative growth is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T15:43:39Z [Term] id: FYPO:0001328 name: abnormal cytoskeleton organization during vegetative growth def: "A cellular process phenotype in which cytoskeleton organization is abnormal in the vegetative growth phase of the cell cycle." [GO:0007010, PomBase:mah] comment: Consider annotating to 'abnormal cytoskeleton morphology' (FYPO:0000352), but note that an abnormal cytoskeleton organization process may, but does not necessarily, result in abnormal cytoskeleton morphology. synonym: "abnormal cytoskeleton organisation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000802 ! abnormal cytoskeleton organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-08-02T17:17:46Z [Term] id: FYPO:0001329 name: decreased level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "reduced level of substance in cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T16:23:22Z [Term] id: FYPO:0001330 name: increased level of substance in cell during vegetative growth def: "A cell phenotype in which the amount of a specific substance measured in a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "increased accumulation of substance in cell during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000990 ! increased level of substance in cell is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-01T16:24:14Z [Term] id: FYPO:0001331 name: cellular process phenotype during vegetative growth def: "A phenotype that affects a cellular process in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast cellular process phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-01T16:27:01Z [Term] id: FYPO:0001332 name: abnormal regulation of translation in response to stress during vegetative growth def: "A gene expression phenotype in which regulation of translation in response to stress is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "protein synthesis after stress, defective during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000263 ! abnormal regulation of translation in response to stress is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-08-01T16:31:58Z [Term] id: FYPO:0001333 name: gene expression regulation phenotype during vegetative growth def: "A regulation phenotype that affects the regulation of gene expression in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast gene expression regulation phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000288 ! gene expression regulation phenotype is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:33:19Z [Term] id: FYPO:0001334 name: regulation phenotype during vegetative growth def: "A cellular process phenotype that affects the regulation of a molecular function, biological process, or biological quality in the vegetative growth phase of the life cycle." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_annotate synonym: "fission yeast regulation phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000145 ! regulation phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:33:52Z [Term] id: FYPO:0001335 name: transcription regulation phenotype during vegetative growth def: "A gene expression phenotype that affects the regulation of DNA-dependent transcription in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast transcription regulation phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "gene-specific transcription regulation phenotype during vegetative growth" RELATED [GO:0006355, PomBase:mah] synonym: "transcriptional control phenotype during vegetative growth" BROAD [GO:0006355, PomBase:mah] is_a: FYPO:0000143 ! transcription regulation phenotype is_a: FYPO:0001333 ! gene expression regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:36:22Z [Term] id: FYPO:0001336 name: transport phenotype during vegetative growth def: "A cell process phenotype that affects a transport process in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast transport phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000149 ! transport phenotype is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:55:04Z [Term] id: FYPO:0001337 name: localization phenotype during vegetative growth def: "A cell phenotype that affects the localization of a structure or substance in a cell in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast localization phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "localisation phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T16:55:18Z [Term] id: FYPO:0001338 name: abnormal nucleus localization during vegetative growth def: "A cellular process phenotype in which nucleus localization is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal nuclear localization during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal nucleus localisation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000517 ! abnormal nucleus localization is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-01T17:07:26Z [Term] id: FYPO:0001339 name: abnormal cellular response to starvation during vegetative growth def: "A stress response phenotype in which the response to starvation for one or more nutrients is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000713 ! abnormal cellular response to starvation is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-08-01T17:15:31Z [Term] id: FYPO:0001340 name: abnormal cellular response to oxidative stress during vegetative growth def: "A stress response phenotype in which a cellular response to oxidative stress is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000180 ! abnormal cellular response to oxidative stress is_a: FYPO:0001341 ! abnormal cellular response to stress during vegetative growth created_by: midori creation_date: 2012-08-01T17:18:23Z [Term] id: FYPO:0001341 name: abnormal cellular response to stress during vegetative growth def: "A cellular response phenotype in which a cellular response to stress is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000162 ! abnormal cellular response to stress is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-01T17:19:19Z [Term] id: FYPO:0001342 name: cellular response phenotype during vegetative growth def: "A cellular process phenotype that affects a response to a stimulus in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast cellular response phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000298 ! cellular response phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:32:10Z [Term] id: FYPO:0001343 name: abnormal DNA replication during vegetative growth def: "A cellular process phenotype in which DNA replication is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal DNA-dependent DNA replication during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000217 ! abnormal DNA replication is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2012-08-01T17:33:51Z [Term] id: FYPO:0001344 name: abnormal DNA replication initiation during vegetative growth def: "A cellular process phenotype in which the initiation of DNA replication is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal DNA-dependent DNA replication initiation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000176 ! abnormal DNA replication initiation is_a: FYPO:0001343 ! abnormal DNA replication during vegetative growth created_by: midori creation_date: 2012-08-01T17:34:25Z [Term] id: FYPO:0001345 name: abnormal DNA recombination during vegetative growth def: "A cellular process phenotype in which DNA recombination is abnormal in the vegetative growth phase of the life cycle. DNA recombination is a process that results in reassortment of genes, producing gene combinations different from those that were present in the parents." [GO:0006310, PomBase:mah] synonym: "recombination defects during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000063 ! abnormal DNA recombination is_a: FYPO:0001346 ! DNA metabolism phenotype during vegetative growth is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2012-08-01T17:37:10Z [Term] id: FYPO:0001346 name: DNA metabolism phenotype during vegetative growth def: "A cellular process phenotype that affects any DNA metabolic process in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast DNA metabolism phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000293 ! DNA metabolism phenotype is_a: FYPO:0001347 ! nucleic acid metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:38:00Z [Term] id: FYPO:0001347 name: nucleic acid metabolism phenotype during vegetative growth def: "A cellular process phenotype that affects any nucleic acid metabolic process in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast nucleic acid metabolism phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000292 ! nucleic acid metabolism phenotype is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:39:21Z [Term] id: FYPO:0001348 name: cellular metabolism phenotype during vegetative growth def: "A cellular process phenotype that affects metabolism in the cell in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "fission yeast cellular metabolism phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000140 ! cellular metabolism phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T17:40:24Z [Term] id: FYPO:0001349 name: abnormal spindle assembly during vegetative growth def: "A cellular process phenotype in which spindle assembly is abnormal in the vegetative growth phase of the life cycle. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle." [GO:0051225, PomBase:mah] is_a: FYPO:0000119 ! abnormal spindle assembly is_a: FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth is_a: FYPO:0001354 ! abnormal cellular component assembly during vegetative growth created_by: midori creation_date: 2012-08-01T17:43:57Z [Term] id: FYPO:0001350 name: abnormal microtubule cytoskeleton organization during vegetative growth def: "A phenotype that affects the organization of the microtubule cytoskeleton in the vegetative growth phase of the life cycle. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GO:0000226, PomBase:mah] comment: Note that an abnormal microtubule cytoskeleton organization process may, but does not necessarily, result in abnormal microtubule cytoskeleton morphology. synonym: "abnormal microtubule cytoskeleton organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal microtubule organisation during vegetative growth" RELATED [PomBase:mah] synonym: "abnormal microtubule organization during vegetative growth" RELATED [PomBase:mah] synonym: "microtubule cytoskeleton defects during vegetative growth" EXACT [PomBase:mah] synonym: "microtubule organization defects during vegetative growth" RELATED [PomBase:mah] is_a: FYPO:0000054 ! abnormal microtubule cytoskeleton organization is_a: FYPO:0001328 ! abnormal cytoskeleton organization during vegetative growth created_by: midori creation_date: 2012-08-01T17:45:38Z [Term] id: FYPO:0001351 name: abnormal membrane organization during vegetative growth def: "A cellular process phenotype in which cellular membrane organization is abnormal in the vegetative growth phase of the life cycle. Cellular membrane organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid bilayer membrane, such as the plasma membrane or an organelle membrane." [GO:0016044, PomBase:mah] synonym: "abnormal cellular membrane organization during vegetative growth" EXACT [GO:0016044, PomBase:mah] synonym: "abnormal membrane organisation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001013 ! abnormal membrane organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-08-01T17:51:07Z [Term] id: FYPO:0001352 name: abnormal chromatin organization during vegetative growth def: "A cellular process phenotype in which any process of chromatin organization is abnormal in the vegetative growth phase of the life cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin." [GO:0006325, PomBase:mah] synonym: "abnormal chromatin organisation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000642 ! abnormal chromatin organization is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-08-01T17:56:15Z [Term] id: FYPO:0001353 name: abnormal cellular component organization during vegetative growth def: "A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal in the vegetative growth phase of the life cycle." [GO:0071842, PomBase:mah] synonym: "abnormal cellular component organisation during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal cellular component organization at cellular level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000335 ! abnormal cellular component organization is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-01T18:11:39Z [Term] id: FYPO:0001354 name: abnormal cellular component assembly during vegetative growth def: "A cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal cellular component assembly at cellular level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000336 ! abnormal cellular component assembly is_a: FYPO:0001353 ! abnormal cellular component organization during vegetative growth created_by: midori creation_date: 2012-08-01T18:14:28Z [Term] id: FYPO:0001355 name: decreased vegetative cell population growth def: "A cell population phenotype in which the growth of a population of cells is decreased relative to normal in the vegetative growth phase of the life cycle. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise (e.g. as for 'decreased cell growth on glucose carbon source' FYPO:0001407). synonym: "aerobic vegetative growth defects" RELATED [PomBase:mah] synonym: "decreased vegetative aerobic cell population growth" NARROW [PomBase:mah] synonym: "reduced vegetative aerobic cell population growth" NARROW [PomBase:mah] synonym: "reduced vegetative growth" BROAD [PomBase:mah] synonym: "slow vegetative aerobic cell population growth" NARROW [PomBase:mah] is_a: FYPO:0000046 ! decreased cell population growth is_a: FYPO:0001356 ! abnormal vegetative cell population growth created_by: midori creation_date: 2012-08-01T18:16:46Z [Term] id: FYPO:0001356 name: abnormal vegetative cell population growth def: "A cellular process phenotype in which vegetative cell population growth is abnormal." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "vegetative growth defect" RELATED [PomBase:mah] is_a: FYPO:0000045 ! abnormal cell population growth is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0001358 ! vegetative cell population growth phenotype created_by: midori creation_date: 2012-08-01T18:17:46Z [Term] id: FYPO:0001357 name: normal vegetative cell population growth def: "A cell population phenotype in which a population of cells grows normally in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "vegetative growth normal" BROAD [PomBase:mah] synonym: "vegetative population growth normal" EXACT [PomBase:mah] is_a: FYPO:0000047 ! normal cell population growth is_a: FYPO:0000627 ! normal cellular process is_a: FYPO:0001358 ! vegetative cell population growth phenotype relationship: has_part FYPO:0001420 ! normal vegetative cell population growth rate created_by: midori creation_date: 2012-08-01T18:20:01Z [Term] id: FYPO:0001358 name: vegetative cell population growth phenotype def: "A cell phenotype that affects the rate or extent of cell population growth in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "cell population growth phenotype during vegetative growth" EXACT [PomBase:mah] synonym: "fission yeast cell population growth phenotype during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000139 ! cell population growth phenotype is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-01T18:21:02Z [Term] id: FYPO:0001360 name: decreased amino acid import during vegetative growth def: "A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased amino acid import into cell during vegetative growth" EXACT [PomBase:al] synonym: "decreased amino acid uptake during vegetative growth" EXACT [GO:0043090] synonym: "reduced amino acid import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001058 ! decreased amino acid import is_a: FYPO:0001361 ! abnormal amino acid import during vegetative growth created_by: midori creation_date: 2012-08-02T14:51:40Z [Term] id: FYPO:0001361 name: abnormal amino acid import during vegetative growth def: "A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "abnormal amino acid import into cell during vegetative growth" EXACT [PomBase:al] synonym: "abnormal amino acid uptake during vegetative growth" EXACT [GO:0043090] is_a: FYPO:0001057 ! abnormal amino acid import is_a: FYPO:0001336 ! transport phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-02T14:52:32Z [Term] id: FYPO:0001362 name: abnormal cellular process during vegetative growth def: "A phenotype in which a specific cellular process is abnormal in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0000628 ! abnormal cellular process is_a: FYPO:0001331 ! cellular process phenotype during vegetative growth created_by: midori creation_date: 2012-08-02T14:55:51Z [Term] id: FYPO:0001363 name: abnormal metabolic process during vegetative growth def: "A cellular process phenotype in which a cellular metabolic process is abnormal in the vegetative growth phase of the life cycle. A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances." [GO:0044237, PomBase:mah] synonym: "abnormal cellular metabolic process during vegetative growth" EXACT [GO:0044237, PomBase:mah] synonym: "abnormal metabolism during vegetative growth" EXACT [GO:0044237, PomBase:mah] is_a: FYPO:0000860 ! abnormal metabolic process is_a: FYPO:0001348 ! cellular metabolism phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-02T18:07:32Z [Term] id: FYPO:0001364 name: abnormal contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring contraction is abnormal. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:0000916, PomBase:mah] synonym: "abnormal actomyosin contractile ring contraction" EXACT [GO:0000916, PomBase:mah] synonym: "abnormal contractile ring constriction" EXACT [PomBase:vw] synonym: "abnormal contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal contractile ring contraction involved in cell cycle cytokinesis" EXACT [PomBase:mah] is_a: FYPO:0000032 ! abnormal cytokinesis created_by: midori creation_date: 2012-08-07T12:39:39Z [Term] id: FYPO:0001365 name: decreased rate of contractile ring contraction def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of contractile ring contraction is decreased. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts." [GO:0000916, PomBase:mah] synonym: "decreased rate of actomyosin contractile ring contraction" EXACT [GO:0000916, PomBase:mah] synonym: "decreased rate of contractile ring constriction" EXACT [PomBase:mah] synonym: "decreased rate of contractile ring contraction during vegetative growth" EXACT [PomBase:mah] synonym: "decreased rate of contractile ring contraction involved in cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "reduced rate of contractile ring contraction" EXACT [PomBase:mah] is_a: FYPO:0000419 ! decreased rate of cytokinesis is_a: FYPO:0001364 ! abnormal contractile ring contraction created_by: midori creation_date: 2012-08-07T12:41:50Z [Term] id: FYPO:0001366 name: normal actin cytoskeleton organization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is normal (i.e. indistinguishable from wild type). Actin cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GO:0030036, PomBase:mah] synonym: "normal actin cytoskeleton organisation" EXACT [PomBase:mah] synonym: "normal actin cytoskeleton organization during vegetative growth" EXACT [PomBase:mah] synonym: "normal actin filament organization" RELATED [PomBase:mah] is_a: FYPO:0000296 ! actin cytoskeleton organization phenotype is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-08-07T12:51:48Z [Term] id: FYPO:0001367 name: normal cytokinesis def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis is normal (i.e. indistinguishable from wild type). Cytokinesis is part of the cell cycle and results in the division of the cytoplasm of a cell and its separation into two daughter cells." [GO:0033205, PomBase:mah] synonym: "normal cell cycle cytokinesis" EXACT [PomBase:mah] synonym: "normal cytokinesis during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth created_by: midori creation_date: 2012-08-07T12:54:44Z [Term] id: FYPO:0001368 name: normal actomyosin contractile ring assembly def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal actomyosin contractile ring assembly during vegetative growth" EXACT [PomBase:mah] synonym: "normal actomyosin contractile ring formation" RELATED [GO:0000915, PomBase:vw] synonym: "normal contractile ring assembly" EXACT [PomBase:mah] synonym: "normal cytokinesis, actomyosin contractile ring assembly" EXACT [PomBase:mah] synonym: "normal cytokinetic ring assembly" RELATED [PomBase:vw] synonym: "normal cytokinetic ring formation" RELATED [PomBase:vw] is_a: FYPO:0001366 ! normal actin cytoskeleton organization is_a: FYPO:0001367 ! normal cytokinesis is_a: FYPO:0001845 ! normal kinetochore organization created_by: midori creation_date: 2012-08-07T12:54:57Z [Term] id: FYPO:0001369 name: mislocalized actomyosin contractile ring def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring in an abnormal location. The normal location is at the midpoint of, and perpendicular to, the long axis of the cell." [PomBase:mah] comment: Note that the location of the contractile ring is determined by the location of the cell division site, so an abnormality in cell division site determination can be inferred from this phenotype. synonym: "contractile ring displaced from cell centre" EXACT [PomBase:vw] synonym: "mislocalised actomyosin contractile ring" EXACT [PomBase:mah] synonym: "mislocalized actomyosin contractile ring during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000350 ! abnormal actin cytoskeleton morphology relationship: output_of FYPO:0000033 ! abnormal contractile ring localization created_by: midori creation_date: 2012-08-07T13:31:19Z [Term] id: FYPO:0001370 name: abnormal protein localization def: "A cell phenotype that affects the localization of a protein in a cell. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "abnormal cellular protein localisation" EXACT [PomBase:mah] synonym: "abnormal cellular protein localization" EXACT [PomBase:mah] synonym: "abnormal protein localisation" EXACT [PomBase:mah] synonym: "protein/peptide distribution: abnormal" RELATED [SGD:phenotype_annotation] is_a: FYPO:0000138 ! localization phenotype is_a: FYPO:0000628 ! abnormal cellular process created_by: midori creation_date: 2012-08-07T13:40:05Z [Term] id: FYPO:0001371 name: abolished protein localization to medial cortex def: "A cell phenotype in which the localization of a protein to the medial cortex is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein localisation to medial cortex abolished" EXACT [GO:0071574, PomBase:mah] synonym: "protein localization to medial cortex abolished" EXACT [PomBase:mah] synonym: "protein localization to medial ring abolished" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001373 ! abnormal protein localization to medial cortex is_a: FYPO:0001375 ! protein localization abolished created_by: midori creation_date: 2012-08-07T13:55:44Z [Term] id: FYPO:0001372 name: abnormal protein localization to medial cortex in spores def: "A cell phenotype in which the localization of a protein to the medial cortex of a spore is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to medial cortex in spores" EXACT [GO:0071574, PomBase:mah] synonym: "abnormal protein localization to medial ring in spores" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001373 ! abnormal protein localization to medial cortex created_by: midori creation_date: 2012-08-07T13:49:04Z [Term] id: FYPO:0001373 name: abnormal protein localization to medial cortex def: "A cell phenotype in which the localization of a protein to the medial cortex is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Encompasses both presence of proteins not normally found at the medial cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. subset: qc_do_not_manually_annotate synonym: "abnormal protein localisation to medial cortex" EXACT [GO:0071574, PomBase:mah] synonym: "abnormal protein localization to medial ring" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-08-07T13:49:11Z [Term] id: FYPO:0001374 name: protein localization to medial cortex abolished in spores def: "A cell phenotype in which the localization of a protein to the medial cortex of a spore is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "protein localisation to medial cortex abolished in spores" EXACT [GO:0071574, PomBase:mah] synonym: "protein localization to medial ring abolished in spores" EXACT [GO:0031097, GO:0071574] is_a: FYPO:0001371 ! abolished protein localization to medial cortex is_a: FYPO:0001372 ! abnormal protein localization to medial cortex in spores created_by: midori creation_date: 2012-08-07T13:56:10Z [Term] id: FYPO:0001375 name: protein localization abolished def: "A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. If this term is used, we recommend noting which protein(s) were used in the assay. subset: qc_do_not_manually_annotate synonym: "abolished protein localization" EXACT [PomBase:mah] synonym: "protein absent from specific location in cell" RELATED [PomBase:mah] is_a: FYPO:0001370 ! abnormal protein localization created_by: midori creation_date: 2012-08-07T13:56:37Z [Term] id: FYPO:0001376 name: normal cellular calcium level during cellular response to salt stress def: "A cell phenotype in which the amount of calcium ion measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular calcium accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal cellular calcium ion level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001199 ! normal cellular calcium level created_by: midori creation_date: 2012-08-07T14:56:53Z [Term] id: FYPO:0001377 name: decreased cellular calcium level during cellular response to salt stress def: "A cell phenotype in which the amount of calcium ion measured in a cell during a cellular response to salt stress is lower than normal." [PomBase:mah] synonym: "decreased calcium accumulation during cellular response to salt stress" RELATED [PomBase:al] synonym: "decreased cellular calcium ion level during cellular response to salt stress" EXACT [PomBase:mah] synonym: "reduced cellular calcium level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001197 ! decreased cellular calcium level created_by: midori creation_date: 2012-08-07T14:58:22Z [Term] id: FYPO:0001378 name: increased cellular calcium level during cellular response to salt stress def: "A cell phenotype in which the amount of calcium ion measured in a cell during a cellular response to salt stress is higher than normal." [PomBase:mah] synonym: "increased calcium accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "increased cellular calcium ion level during cellular response to salt stress" EXACT [PomBase:mah] is_a: FYPO:0001198 ! increased cellular calcium level created_by: midori creation_date: 2012-08-07T14:58:54Z [Term] id: FYPO:0001379 name: resistance to tacrolimus def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tacrolimus than normal." [PomBase:mah] synonym: "resistance to FK506" EXACT [CHEBI:61057, PomBase:mah] synonym: "resistance to tacrolimus during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tacrolimus" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-08-07T15:05:20Z [Term] id: FYPO:0001380 name: normal nuclear morphology during vegetative growth def: "A cellular structure phenotype in which the morphology of the nucleus is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle." [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular structure during vegetative growth is_a: FYPO:0001673 ! normal nuclear morphology created_by: midori creation_date: 2012-08-07T15:06:55Z [Term] id: FYPO:0001381 name: abnormal protein kinase activity def: "A molecular function phenotype in which the observed rate of a protein kinase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-08-09T16:05:03Z [Term] id: FYPO:0001382 name: decreased protein kinase activity def: "A molecular function phenotype in which the observed rate of a protein kinase activity is decreased." [PomBase:mah] synonym: "reduced protein kinase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2012-08-09T16:06:18Z [Term] id: FYPO:0001383 name: normal DNA content def: "A cell phenotype in which the amount of DNA measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0001076 ! normal level of substance in cell created_by: midori creation_date: 2012-08-09T16:33:17Z [Term] id: FYPO:0001384 name: abolished protein kinase activity def: "A molecular function phenotype in which a protein kinase activity is absent." [PomBase:mah] synonym: "protein kinase activity abolished" EXACT [PomBase:mah] is_a: FYPO:0000664 ! abolished catalytic activity is_a: FYPO:0001381 ! abnormal protein kinase activity created_by: midori creation_date: 2012-08-10T13:54:04Z [Term] id: FYPO:0001385 name: inviable after spore germination, cell cycle arrest with replicated DNA def: "A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest with replicated DNA, and eventually dies." [PMID:9705504, PomBase:mah] synonym: "essential; germinating spore, cell cycle arrest with replicated DNA" RELATED [PomBase:mah] synonym: "inviable following spore germination, cell cycle arrest with replicated DNA" EXACT [PomBase:mah] synonym: "inviable germinating spore, cell cycle arrest with replicated DNA" RELATED [PomBase:mah] is_a: FYPO:0001924 ! inviable after spore germination, cell cycle arrest relationship: has_part FYPO:0000444 ! cell cycle arrest with replicated DNA created_by: midori creation_date: 2012-08-10T14:06:51Z [Term] id: FYPO:0001386 name: increased haploidization alt_id: FYPO:0001781 def: "A cell phenotype in which non-sporulating diploid cells become haploid, without undergoing meiosis, at a higher frequency than normal." [PMID:9914167, PomBase:al, PomBase:mah] comment: Diploid cells may become haploid by chromosome loss, or by undergoing premature mitosis. Chromosome loss may also cause aneuploidy or cell death. synonym: "unstable diploid" EXACT [PomBase:mah] is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-10T14:51:16Z [Term] id: FYPO:0001387 name: loss of viability at high temperature def: "A cell population phenotype in which a smaller than normal proportion of the population remains viable when are grown at a temperature higher than standard." [PomBase:mah] comment: For S. pombe, high temperature usually means above 32 degrees C. Use this term to annotate experiments in which a culture is grown at high temperature, and then the number of cells viable enough to form a colony upon return to standard or low temperature is measured and compared to wild type. synonym: "loss of viability at restrictive temperature" RELATED [PomBase:mah] is_a: FYPO:0001985 ! abnormal phenotype is_a: FYPO:0002057 ! cell population viability relationship: includes_cells_with_phenotype FYPO:0000713 ! abnormal cellular response to starvation created_by: midori creation_date: 2012-08-10T14:55:36Z [Term] id: FYPO:0001388 name: decreased protein level in germinating spore def: "A cell phenotype in which the amount of protein measured in a cell is lower than normal during or just after spore germination. Total protein or a specific protein may be affected." [PomBase:mah] is_a: FYPO:0000835 ! decreased protein level created_by: midori creation_date: 2012-08-10T16:32:24Z [Term] id: FYPO:0001389 name: normal nucleus localization def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleus localization is normal." [PomBase:mah] synonym: "normal nuclear localization" EXACT [PomBase:mah] synonym: "normal nuclear position" EXACT [PomBase:mah] synonym: "normal nucleus localisation" EXACT [PomBase:mah] synonym: "normal nucleus localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001337 ! localization phenotype during vegetative growth created_by: midori creation_date: 2012-08-15T11:46:28Z [Term] id: FYPO:0001390 name: misoriented septum def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is not perpendicular to the long axis of the cell." [PomBase:mah] synonym: "abnormal septum orientation" EXACT [PomBase:mah] synonym: "misoriented septum during vegetative growth" EXACT [PomBase:mah] synonym: "tilted septum" EXACT [PomBase:al] is_a: FYPO:0002023 ! abnormal septum morphology created_by: midori creation_date: 2012-08-15T13:03:09Z [Term] id: FYPO:0001391 name: mislocalized septum, near new end def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum closer to the new end of the cell (when the new end is not yet growing), instead of at the midpoint of the long axis." [PomBase:mah] synonym: "abnormal septum location, near new end" EXACT [PomBase:mah] synonym: "abnormal septum location, near non-growing end" NARROW [PomBase:mah] synonym: "abnormal septum position, near new end" EXACT [PomBase:mah] synonym: "abnormal septum position, near non-growing end" NARROW [PomBase:mah] synonym: "asymmetric septum, near new end" EXACT [PomBase:mah] synonym: "asymmetric septum, near non-growing end" NARROW [PomBase:mah] synonym: "asymmetrically located septum, near new end" EXACT [PomBase:mah] synonym: "asymmetrically located septum, near non-growing end" NARROW [PomBase:mah] synonym: "mislocalised septum, near new end" EXACT [PomBase:mah] synonym: "mislocalised septum, near non-growing end" NARROW [PomBase:mah] synonym: "mislocalized septum, near new end, during vegetative growth" EXACT [PomBase:mah] synonym: "mislocalized septum, near non-growing end" NARROW [PomBase:mah] synonym: "mislocalized septum, near non-growing end, during vegetative growth" NARROW [PomBase:mah] is_a: FYPO:0000339 ! mislocalized septum is_a: FYPO:0001225 ! monoseptate created_by: midori creation_date: 2012-08-15T13:08:14Z [Term] id: FYPO:0001392 name: abnormal regulation of cell growth def: "A regulation phenotype in which regulation of vegetative cell growth is abnormal." [PomBase:mah] synonym: "abnormal regulation of vegetative cell growth" EXACT [PomBase:mah] is_a: FYPO:0001334 ! regulation phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-15T13:20:37Z [Term] id: FYPO:0001393 name: abnormal activation of monopolar cell growth def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, is abnormal." [PomBase:mah] synonym: "abnormal regulation of monopolar vegetative cell growth" EXACT [PomBase:mah] is_a: FYPO:0001392 ! abnormal regulation of cell growth created_by: midori creation_date: 2012-08-15T13:21:29Z [Term] id: FYPO:0001394 name: activation of monopolar cell growth at either end def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth may occur at either the new or old end of the cell, instead of exclusively at the old end, following cell division. A population of cells with this phenotype has a 1:1 mix of cells initiating growth at the new end and cells initiating growth at the old end." [PomBase:mah] synonym: "abnormal initiation of growth from either old or new end following cell division" EXACT [PomBase:al] synonym: "activation of monopolar vegetative cell growth at either end" EXACT [PomBase:mah] is_a: FYPO:0001393 ! abnormal activation of monopolar cell growth created_by: midori creation_date: 2012-08-15T13:23:28Z [Term] id: FYPO:0001395 name: normal activation of monopolar cell growth def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal activation of monopolar vegetative cell growth" EXACT [PomBase:mah] synonym: "normal initiation of growth from old end following cell division" EXACT [PomBase:al] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-15T13:35:02Z [Term] id: FYPO:0001396 name: normal activation of bipolar cell growth def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which activation of bipolar cell growth is normal; results in normal new end take-off." [PomBase:mah] synonym: "normal activation of bipolar vegetative cell growth" EXACT [PomBase:mah] synonym: "normal NETO" EXACT [PomBase:mah] synonym: "normal new end take off" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-15T13:48:18Z [Term] id: FYPO:0001397 name: monopolar actin cortical patch localization to old end def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only the old end of a cell following cell division." [PomBase:mah] synonym: "monopolar actin cortical patch localisation to old end" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch localization to old end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001019 ! monopolar actin cortical patch localization created_by: midori creation_date: 2012-08-15T14:00:14Z [Term] id: FYPO:0001398 name: monopolar actin cortical patch localization to either end def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only one end of a cell following cell division; patches may localize to either the old or the new end. A population of cells with this phenotype has a 1:1 mix of cells with actin patches at the old end and cells with patches at the new end." [PomBase:mah] synonym: "monopolar actin cortical patch localisation to either end" EXACT [PomBase:mah] synonym: "monopolar actin cortical patch localization to either end during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001019 ! monopolar actin cortical patch localization created_by: midori creation_date: 2012-08-15T14:06:42Z [Term] id: FYPO:0001399 name: normal mitotic spindle def: "A cellular structure phenotype in which the structure of the mitotic spindle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal mitotic spindle during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001313 ! normal subcellular structure during vegetative growth created_by: midori creation_date: 2012-08-15T14:29:30Z [Term] id: FYPO:0001400 name: normal interphase cytoplasmic microtubules def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the structure of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle." [PomBase:mah] synonym: "normal cytoplasmic microtubules during interphase" EXACT [PomBase:mah] synonym: "normal interphase cytoplasmic microtubules during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001976 ! normal cytoplasmic microtubules created_by: midori creation_date: 2012-08-15T14:40:33Z [Term] id: FYPO:0001401 name: abnormal protein localization to cell division site def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found at the cell cortex and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell division site" EXACT [PomBase:mah] synonym: "abnormal protein localization to cell division site during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-08-15T15:14:14Z [Term] id: FYPO:0001402 name: normal protein localization to cell cortex def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell cortex" EXACT [PomBase:mah] synonym: "normal protein localization to cell cortex during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization created_by: midori creation_date: 2012-08-15T15:15:59Z [Term] id: FYPO:0001403 name: increased cell-substrate adhesion def: "A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells adhere to a substrate more strongly or to a greater extent than normal." [PomBase:mah] synonym: "increased cell-substrate adhesion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000009 ! abnormal cell adhesion during vegetative growth created_by: midori creation_date: 2012-08-15T15:36:37Z [Term] id: FYPO:0001404 name: irregular colony morphology def: "A colony morphology phenotype in which the outline of a colony growing on a solid surface is not symmetrical." [PomBase:mah, PomBase:mp] is_a: FYPO:0000150 ! abnormal colony morphology created_by: midori creation_date: 2012-08-15T15:38:42Z [Term] id: FYPO:0001405 name: glossy colony morphology def: "A colony morphology phenotype in which a colony growing on a solid surface has an abnormally glossy surface." [PomBase:mah, PomBase:mp] synonym: "smooth colony morphology" RELATED [PomBase:vw] is_a: FYPO:0000150 ! abnormal colony morphology created_by: midori creation_date: 2012-08-15T15:40:06Z [Term] id: FYPO:0001406 name: increased septum thickness def: "A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is thicker than normal." [PomBase:mah] synonym: "increased septum thickness during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0002023 ! abnormal septum morphology created_by: midori creation_date: 2012-08-15T15:43:42Z [Term] id: FYPO:0001407 name: decreased cell population growth on glucose carbon source def: "A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glucose as the carbon source." [PomBase:mah] comment: Note that this term encompasses growth under aerobic or semi-anaerobic conditions, whereas most cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "decreased growth on glucose carbon source" BROAD [PomBase:mah] synonym: "decreased vegetative cell growth on glucose carbon source" EXACT [PomBase:mah] synonym: "reduced cell growth on glucose carbon source" EXACT [PomBase:mah] synonym: "slow cell growth on glucose carbon source" NARROW [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-16T15:53:30Z [Term] id: FYPO:0001408 name: sensitive to heat shock def: "A cell phenotype in which cells show increased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature." [PomBase:mah] synonym: "hypersensitive to heat shock" EXACT [PomBase:mah] is_a: FYPO:0000082 ! sensitive to high temperature created_by: midori creation_date: 2012-08-16T16:02:56Z [Term] id: FYPO:0001409 name: normal cell population growth on glycerol carbon source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing glycerol as the carbon source." [PomBase:mah] synonym: "normal growth on glycerol carbon source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on glycerol carbon source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-16T16:19:09Z [Term] id: FYPO:0001410 name: normal cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-), also called acid labile sulfide) measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "normal cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "normal cellular sulfide ion level" EXACT [PomBase:mah] synonym: "normal cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular sulphide level" EXACT [PomBase:mah] is_a: FYPO:0001544 ! normal cellular sulfur level created_by: midori creation_date: 2012-08-16T16:41:11Z [Term] id: FYPO:0001411 name: altered cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular sulfide level" EXACT [PomBase:mah] synonym: "altered cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "altered cellular sulfide ion level" EXACT [PomBase:mah] synonym: "altered cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "altered cellular sulphide level" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-16T16:43:19Z [Term] id: FYPO:0001412 name: decreased cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "decreased cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "decreased cellular sulfide ion level" EXACT [PomBase:mah] synonym: "decreased cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular sulphide level" EXACT [PomBase:mah] synonym: "reduced cellular sulfide level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001411 ! altered cellular sulfide level created_by: midori creation_date: 2012-08-16T16:54:55Z [Term] id: FYPO:0001413 name: increased cellular sulfide level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular acid labile sulfide level" EXACT [PomBase:al] synonym: "increased cellular sulfide accumulation" RELATED [PomBase:mah] synonym: "increased cellular sulfide ion level" EXACT [PomBase:mah] synonym: "increased cellular sulfide level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular sulphide level" EXACT [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001411 ! altered cellular sulfide level created_by: midori creation_date: 2012-08-16T16:56:12Z [Term] id: FYPO:0001414 name: sensitive to sulfide def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sulfide (S2-). Cells stop growing (and may die) at a concentration of sulfide ions that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to sulfide" EXACT [PomBase:mah] synonym: "sensitive to sulfide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-08-16T17:01:57Z [Term] id: FYPO:0001415 name: abnormal sulfide:quinone oxidoreductase activity def: "A molecular function phenotype in which the observed rate of sulfide:quinone oxidoreductase activity is abnormal." [PomBase:mah] synonym: "abnormal sulfide-quinone reductase activity" EXACT [GO:0070224] synonym: "abnormal sulfide:quinone reductase activity" EXACT [PomBase:al] synonym: "abnormal sulphide:quinone oxidoreductase activity" EXACT [PomBase:mah] is_a: FYPO:0000689 ! abnormal oxidoreductase activity created_by: midori creation_date: 2012-08-16T17:02:48Z [Term] id: FYPO:0001416 name: decreased sulfide:quinone oxidoreductase activity def: "A molecular function phenotype in which the observed rate of sulfide:quinone oxidoreductase activity is decreased." [PomBase:mah] synonym: "decreased sulfide-quinone reductase activity" EXACT [GO:0070224] synonym: "decreased sulfide:quinone reductase activity" EXACT [PomBase:al] synonym: "decreased sulphide:quinone oxidoreductase activity" EXACT [PomBase:mah] synonym: "reduced sulfide:quinone oxidoreductase activity" EXACT [PomBase:mah] is_a: FYPO:0000690 ! decreased oxidoreductase activity is_a: FYPO:0001415 ! abnormal sulfide:quinone oxidoreductase activity created_by: midori creation_date: 2012-08-16T17:03:37Z [Term] id: FYPO:0001417 name: mislocalized equatorial microtubule organizing center def: "A cell phenotype in which a cell forms an equatorial microtubule organizing center in an abnormal location. The normal location is at the center of the cell." [PomBase:mah] synonym: "mislocalised equatorial microtubule organizing center" EXACT [PomBase:mah] is_a: FYPO:0001418 ! abnormal microtubule cytoskeleton morphology created_by: midori creation_date: 2012-08-22T11:59:56Z [Term] id: FYPO:0001418 name: abnormal microtubule cytoskeleton morphology def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the morphology of the microtubule cytoskeleton is abnormal." [PomBase:mah] comment: Note that an abnormal actin cytoskeleton organization process may, but does not necessarily, result in abnormal actin cytoskeleton morphology. synonym: "abnormal microtubule cytoskeleton morphology during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000352 ! abnormal cytoskeleton morphology relationship: output_of FYPO:0001350 ! abnormal microtubule cytoskeleton organization during vegetative growth created_by: midori creation_date: 2012-08-22T12:00:57Z [Term] id: FYPO:0001419 name: normal cell population growth rate def: "A cell population phenotype in which a population of cells grows at the same rate as wild type." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate synonym: "normal growth rate" BROAD [PomBase:mah] is_a: FYPO:0002058 ! viable cell population created_by: midori creation_date: 2012-08-22T13:05:17Z [Term] id: FYPO:0001420 name: normal vegetative cell population growth rate def: "A cell population phenotype in which a population of cells grow at the same rate as wild type in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "normal growth rate" BROAD [PomBase:mah] is_a: FYPO:0000114 ! cellular process phenotype is_a: FYPO:0001419 ! normal cell population growth rate created_by: midori creation_date: 2012-08-22T13:07:40Z [Term] id: FYPO:0001421 name: abnormal protein processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein processing is abnormal. Protein processing is the cleavage of one or more bonds within a protein that leads to the formation of mature, fully functional protein." [GO:0030163, PomBase:mah] synonym: "abnormal protein cleavage" RELATED [PomBase:vw] synonym: "abnormal protein maturation by peptide bond cleavage" EXACT [GO:0016485] synonym: "abnormal protein maturation by peptide bond hydrolysis" EXACT [GO:0016485] synonym: "abnormal protein processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000328 ! abnormal protein metabolic process created_by: midori creation_date: 2012-08-22T13:47:53Z [Term] id: FYPO:0001422 name: decreased protein processing def: "A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which the observed occurrence of protein processing is decreased." [PMID:19520858, PomBase:mah] synonym: "decreased protein cleavage" RELATED [PomBase:vw] synonym: "decreased protein maturation by peptide bond cleavage" EXACT [GO:0016485] synonym: "decreased protein maturation by peptide bond hydrolysis" EXACT [GO:0016485] synonym: "decreased protein processing during vegetative growth" EXACT [PomBase:mah] synonym: "decreased Sre1 cleavage" NARROW [PomBase:mah] synonym: "reduced protein processing" EXACT [PomBase:mah] is_a: FYPO:0001421 ! abnormal protein processing created_by: midori creation_date: 2012-08-22T14:19:01Z [Term] id: FYPO:0001423 name: normal protein targeting to vacuole def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein targeting to vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar protein sorting" EXACT [PomBase:mah] is_a: FYPO:0000601 ! normal vacuolar transport created_by: midori creation_date: 2012-08-22T14:28:30Z [Term] id: FYPO:0001424 name: abolished protein localization to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to nucleus" EXACT [PomBase:mah] synonym: "abolished protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to nucleus abolished" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus is_a: FYPO:0001179 ! protein localization abolished during vegetative growth created_by: midori creation_date: 2012-08-22T14:54:11Z [Term] id: FYPO:0001425 name: abnormal negative regulation of DNA replication initiation resulting in complete rereplication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome." [PMID:10388806, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during vegetative growth, resulting in complete rereplication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation resulting in complete rereplication" EXACT [PomBase:mah] synonym: "complete DNA re-replication" RELATED [PomBase:mah] synonym: "complete DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0000216 ! abnormal negative regulation of DNA replication initiation created_by: midori creation_date: 2012-08-22T15:01:52Z [Term] id: FYPO:0001426 name: abnormal negative regulation of DNA replication initiation resulting in partial rereplication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, resulting in rereplication of part of the genome." [PMID:10388806, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during vegetative growth, resulting in partial rereplication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation resulting in partial rereplication" EXACT [PomBase:mah] synonym: "partial DNA re-replication" RELATED [PomBase:mah] synonym: "partial DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0000216 ! abnormal negative regulation of DNA replication initiation created_by: midori creation_date: 2012-08-22T15:05:13Z [Term] id: FYPO:0001427 name: abnormal negative regulation of DNA replication initiation resulting in slow rereplication def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, resulting in a single round of rereplication of the entire genome, which takes place more slowly than normal replication." [PMID:10388806, PomBase:mah] synonym: "abnormal negative regulation of DNA replication initiation during vegetative growth, resulting in slow rereplication" EXACT [PomBase:mah] synonym: "abnormal negative regulation of DNA-dependent DNA replication initiation resulting in slow rereplication" EXACT [PomBase:mah] synonym: "slow DNA re-replication" RELATED [PomBase:mah] synonym: "slow DNA rereplication" RELATED [PomBase:mah] is_a: FYPO:0000216 ! abnormal negative regulation of DNA replication initiation created_by: midori creation_date: 2012-08-22T15:06:50Z [Term] id: FYPO:0001428 name: normal negative regulation of DNA replication initiation def: "A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal negative regulation of DNA replication initiation during vegetative growth" EXACT [PomBase:mah] synonym: "normal negative regulation of DNA-dependent DNA replication initiation" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001334 ! regulation phenotype during vegetative growth created_by: midori creation_date: 2012-08-22T15:08:32Z [Term] id: FYPO:0001429 name: swollen elongated cell def: "A cell morphology phenotype in which a cell has a larger volume, and is longer, than normal." [PMID:10388806, PomBase:mah] comment: The distinction between this phenotype and dumbbell-shaped cells (FYPO:0000779) is that swollen elongated cells do not have a constriction along the long axis. Swollen elongated cells may have a uniform diameter, or may be swollen only around the nucleus. is_a: FYPO:0000017 ! elongated cell is_a: FYPO:0000025 ! swollen cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000025 ! swollen cell created_by: midori creation_date: 2012-08-22T15:16:12Z [Term] id: FYPO:0001430 name: cell cycle arrest with unreplicated DNA def: "A cellular process phenotype in which progression through the mitotic cell cycle is arrested before cells have replicated genomic DNA." [PomBase:mah] comment: Arrest with replicated DNA may occur between mitosis and the beginning of S phase; if only DNA content is measured, the arrest point cannot be determined with greater precision. synonym: "cell cycle arrest with 1C DNA content" NARROW [PomBase:mah] synonym: "cell cycle arrest with unreplicated DNA during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000407 ! abnormally arrested cell cycle progression created_by: midori creation_date: 2012-08-22T15:27:17Z [Term] id: FYPO:0001431 name: resistance to Dio-9 def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of the antibiotic Dio-9 than normal." [PomBase:mah] comment: DIO 9 has CAS registry number 11006-20-5. synonym: "resistance to DIO 9" EXACT [PomBase:mah] synonym: "resistance to Dio-9 during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to Dio-9" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-08-23T12:22:31Z [Term] id: FYPO:0001432 name: resistance to ethidium bromide def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethidium bromide than normal." [PomBase:mah] synonym: "resistance to EtBr" EXACT [PomBase:mah] synonym: "resistance to ethidium bromide during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to ethidium bromide" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-08-23T12:45:11Z [Term] id: FYPO:0001433 name: resistance to decamethylenediguanidine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of decamethylenediguanidine than normal." [PomBase:mah] synonym: "resistance to Anticoman" EXACT [CHEBI:768260, PomBase:mah] synonym: "resistance to decamethylenediguanidine during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to decamethylenediguanidine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-08-23T12:49:28Z [Term] id: FYPO:0001434 name: resistance to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N,N'-(p-xylylidene)bis-aminoguanidine 2HCl than normal." [PomBase:mah] synonym: "resistance to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-08-23T12:50:30Z [Term] id: FYPO:0001435 name: normal cell population growth on erythromycin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing erythromycin." [PomBase:mah] synonym: "normal cell population growth in presence of erythromycin" EXACT [PomBase:mah] synonym: "normal cellular response to erythromycin" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on erythromycin" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on erythromycin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:53:50Z [Term] id: FYPO:0001436 name: normal cell population growth on trichodermin def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing trichodermin." [PomBase:mah] synonym: "normal cell population growth in presence of trichodermin" EXACT [PomBase:mah] synonym: "normal cellular response to trichodermin" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on trichodermin" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on trichodermin" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:55:40Z [Term] id: FYPO:0001437 name: normal cell population growth on antimycin A def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing antimycin A." [PomBase:mah] synonym: "normal cell population growth in presence of antimycin A" EXACT [PomBase:mah] synonym: "normal cellular response to antimycin A" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on antimycin A" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on antimycin A" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:56:12Z [Term] id: FYPO:0001438 name: normal cell population growth on tetracycline def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tetracycline." [PomBase:mah] synonym: "normal cell population growth in presence of tetracycline" EXACT [PomBase:mah] synonym: "normal cellular response to tetracycline" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on tetracycline" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on tetracycline" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:58:33Z [Term] id: FYPO:0001439 name: normal cell population growth on chloramphenicol def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chloramphenicol." [PomBase:mah] synonym: "normal cell population growth in presence of chloramphenicol" EXACT [PomBase:mah] synonym: "normal cellular response to chloramphenicol" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on chloramphenicol" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on chloramphenicol" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T12:59:01Z [Term] id: FYPO:0001440 name: abnormal protein complex localization def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal." [PomBase:mah] synonym: "abnormal cellular protein complex localization" EXACT [GO:0034629, PomBase:mah] synonym: "abnormal protein complex localisation" EXACT [GO:0034629, PomBase:mah] synonym: "abnormal protein complex localization during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-08-23T14:24:05Z [Term] id: FYPO:0001441 name: decreased SAGA complex localization to promoter region def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is decreased." [PomBase:mah] synonym: "decreased SAGA complex localisation to promoter region" EXACT [PomBase:mah] synonym: "decreased SAGA complex localization to promoter region during vegetative growth" EXACT [PomBase:mah] synonym: "decreased SAGA complex localization to transcription regulatory region" EXACT [GO:0072742, PomBase:mah] synonym: "decreased SAGA complex recruitment" EXACT [GO:0072742, PomBase:mah] synonym: "reduced SAGA complex localization to promoter region" EXACT [PomBase:mah] synonym: "reduced SAGA complex recruitment" EXACT [PomBase:vw] is_a: FYPO:0001440 ! abnormal protein complex localization created_by: midori creation_date: 2012-08-23T14:34:58Z [Term] id: FYPO:0001442 name: decreased histone H3-K9 acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K9 acetylation" EXACT [GO:0043970, PomBase:mah] synonym: "decreased histone H3-K9 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K9 acetylation" EXACT [GO:0043970, PomBase:mah] synonym: "reduced histone H3-K9 acetylation" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation is_a: FYPO:0000891 ! abnormal histone H3-K9 acetylation created_by: midori creation_date: 2012-08-23T14:45:03Z [Term] id: FYPO:0001443 name: abolished transcription def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription does not occur. All genes, or a specific subset of genes, may be affected." [PomBase:mah] synonym: "abolished transcription during vegetative growth" EXACT [PomBase:mah] synonym: "transcription abolished" EXACT [PomBase:mah] is_a: FYPO:0000781 ! decreased transcription created_by: midori creation_date: 2012-08-23T14:53:02Z [Term] id: FYPO:0001444 name: increased cellular trehalose level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular trehalose level during vegetative growth" EXACT [PomBase:mah] synonym: "increased trehalose accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth is_a: FYPO:0001446 ! altered cellular trehalose level created_by: midori creation_date: 2012-08-23T15:18:12Z [Term] id: FYPO:0001445 name: increased cellular trehalose level during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal when the cell is subject to heat shock." [PomBase:mah] synonym: "increased cellular trehalose level during vegetative growth and during heat shock" EXACT [PomBase:mah] synonym: "increased trehalose accumulation during heat shock" RELATED [PomBase:mah] is_a: FYPO:0001444 ! increased cellular trehalose level created_by: midori creation_date: 2012-08-23T15:19:11Z [Term] id: FYPO:0001446 name: altered cellular trehalose level def: "A cell phenotype in which the amount of trehalose measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular trehalose accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular trehalose level" EXACT [PomBase:mah] is_a: FYPO:0000989 ! altered level of substance in cell created_by: midori creation_date: 2012-08-23T15:22:37Z [Term] id: FYPO:0001447 name: decreased cellular trehalose level def: "A cell phenotype in which the amount of trehalose measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular trehalose accumulation" RELATED [PomBase:mah] synonym: "reduced cellular trehalose level" EXACT [PomBase:mah] is_a: FYPO:0000991 ! decreased level of substance in cell is_a: FYPO:0001446 ! altered cellular trehalose level created_by: midori creation_date: 2012-08-23T15:24:19Z [Term] id: FYPO:0001448 name: trehalose absent from cell during heat shock def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is too low to detect." [PomBase:mah] synonym: "absent trehalose" EXACT [PomBase:al] synonym: "trehalose absent from cell during vegetative growth and during heat shock" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth is_a: FYPO:0001446 ! altered cellular trehalose level created_by: midori creation_date: 2012-08-23T15:26:41Z [Term] id: FYPO:0001449 name: normal cellular trehalose level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular trehalose accumulation" RELATED [PomBase:mah] synonym: "normal cellular trehalose level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-23T15:28:23Z [Term] id: FYPO:0001450 name: resistance to cold def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to cold." [PomBase:mah] synonym: "resistance to cold during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to cold" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2012-08-23T15:46:25Z [Term] id: FYPO:0001451 name: resistance to freezing def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to freezing." [PomBase:mah] synonym: "resistance to freezing during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to freeze-thawing" RELATED [PomBase:al] synonym: "resistant to freezing" EXACT [PomBase:mah] is_a: FYPO:0001450 ! resistance to cold created_by: midori creation_date: 2012-08-23T15:47:42Z [Term] id: FYPO:0001452 name: resistance to water deprivation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to water deprivation." [PomBase:mah] synonym: "resistance to water deprivation during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to dehydration" EXACT [GO:0009414, PomBase:al] synonym: "resistant to water deprivation" EXACT [PomBase:mah] is_a: FYPO:0000850 ! resistance to stress during vegetative growth created_by: midori creation_date: 2012-08-23T15:49:03Z [Term] id: FYPO:0001453 name: resistance to ethanol def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethanol than normal." [PomBase:mah] synonym: "resistance to ethanol during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to ethyl alcohol" EXACT [CHEBI:16236] synonym: "resistant to ethanol" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-08-23T15:50:53Z [Term] id: FYPO:0001454 name: normal cell population growth during cellular response to freezing def: "A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) during a cellular response to freezing conditions." [PomBase:mah] synonym: "normal cellular response to freeze-thawing" RELATED [PomBase:al] synonym: "normal cellular response to freezing" RELATED [PomBase:mah] synonym: "normal vegetative cell population growth during cellular response to freezing" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-23T15:54:30Z [Term] id: FYPO:0001455 name: normal cellular response to water deprivation def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to water deprivation is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to dehydration" EXACT [GO:0009414, GO:0042631, PomBase:al] synonym: "normal cellular response to water deprivation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-08-23T15:58:02Z [Term] id: FYPO:0001456 name: increased RNA level during cellular response to endoplasmic reticulum stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to endoplasmic reticulum stress is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mRNA level during cellular response to endoplasmic reticulum stress" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to endoplasmic reticulum stress" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to endoplasmic reticulum stress during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during response to ER stress" EXACT [GO:0034976, PomBase:mah] synonym: "increased RNA level under ER stress-inducing conditions" RELATED [PomBase:vw] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-08-23T16:26:07Z [Term] id: FYPO:0001457 name: sensitive to tunicamycin def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tunicamycin. Cells stop growing (and may die) at a concentration of tunicamycin that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to tunicamycin" EXACT [PomBase:mah] synonym: "sensitive to tunicamycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-08-23T16:33:02Z [Term] id: FYPO:0001458 name: decreased histone H3-K14 acetylation def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histone H3 K14 acetylation" EXACT [GO:0044154, PomBase:mah] synonym: "decreased histone H3-K14 acetylation during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histone lysine H3 K14 acetylation" EXACT [GO:0044154, PomBase:mah] synonym: "reduced histone H3-K14 acetylation" EXACT [PomBase:mah] is_a: FYPO:0000331 ! decreased histone acetylation is_a: FYPO:0000788 ! abnormal histone H3-K14 acetylation created_by: midori creation_date: 2012-08-24T14:22:25Z [Term] id: FYPO:0001459 name: increased basal transcription from CDRE promoter def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the level of transcription from a calcineurin-dependent response element (CDRE)-containing promoter is higher than normal in the absence of a calcium ion stimulus." [PMID:21811607, PomBase:mah] synonym: "increased basal transcription from CDRE promoter during vegetative growth" EXACT [PomBase:mah] synonym: "increased transcription from CRDE promoter in the absence of calcium" EXACT [PomBase:al] is_a: FYPO:0000780 ! increased transcription created_by: midori creation_date: 2012-08-29T14:03:47Z [Term] id: FYPO:0001460 name: increased duration of positive regulation of transcription from CDRE promoter in response to calcium ion def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is increased for longer than normal following a calcium ion stimulus." [PMID:21811607, PomBase:mah] synonym: "increased duration of positive regulation of transcription from CDRE promoter in response to calcium ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000780 ! increased transcription created_by: midori creation_date: 2012-08-29T14:14:33Z [Term] id: FYPO:0001461 name: normal immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases normally immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "normal immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001199 ! normal cellular calcium level created_by: midori creation_date: 2012-08-29T14:47:54Z [Term] id: FYPO:0001462 name: altered cellular calcium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell differs from normal." [PomBase:mah] synonym: "abnormal cellular calcium accumulation" RELATED [PomBase:mah] synonym: "abnormal cellular calcium level" EXACT [PomBase:mah] synonym: "altered cellular calcium ion level" EXACT [PomBase:mah] synonym: "altered cellular calcium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-08-29T14:51:00Z [Term] id: FYPO:0001463 name: abnormal immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases abnormally, or does not change, immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "abnormal immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-08-29T14:59:29Z [Term] id: FYPO:0001464 name: increased immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases to a greater extent than normal immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "increased immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001198 ! increased cellular calcium level is_a: FYPO:0001463 ! abnormal immediate intracellular calcium spike following extracellular calcium stimulus created_by: midori creation_date: 2012-08-29T15:00:24Z [Term] id: FYPO:0001465 name: decreased immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases to a lesser extent than normal immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "decreased immediate intracellular calcium spike following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced immediate intracellular calcium spike following extracellular calcium stimulus" EXACT [PomBase:mah] is_a: FYPO:0001463 ! abnormal immediate intracellular calcium spike following extracellular calcium stimulus created_by: midori creation_date: 2012-08-29T15:03:36Z [Term] id: FYPO:0001466 name: abolished immediate intracellular calcium spike following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration does not increase immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a \"burst\" within one minute, and then decreases to a new steady-state concentration." [PMID:21811607, PomBase:mah] synonym: "immediate intracellular calcium spike following extracellular calcium stimulus abolished" EXACT [PomBase:mah] synonym: "immediate intracellular calcium spike following extracellular calcium stimulus abolished during vegetative growth" EXACT [PomBase:mah] synonym: "immediate intracellular calcium spike following extracellular calcium stimulus absent" EXACT [PomBase:mah] is_a: FYPO:0001463 ! abnormal immediate intracellular calcium spike following extracellular calcium stimulus created_by: midori creation_date: 2012-08-29T15:32:06Z [Term] id: FYPO:0001467 name: normal increase in steady-state intracellular calcium level following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases normally following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours." [PMID:21811607, PomBase:mah] synonym: "normal increase in steady-state intracellular calcium level following extracellular calcium stimulus" EXACT [PomBase:mah] synonym: "normal increase in steady-state intracellular calcium level following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001199 ! normal cellular calcium level created_by: midori creation_date: 2012-08-29T15:52:34Z [Term] id: FYPO:0001468 name: abnormal steady-state intracellular calcium level following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases abnormally, or does not change, following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours." [PMID:21811607, PomBase:mah] synonym: "abnormal increase in steady-state intracellular calcium level following extracellular calcium stimulus" EXACT [PomBase:mah] synonym: "abnormal increase in steady-state intracellular calcium level following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001462 ! altered cellular calcium level created_by: midori creation_date: 2012-08-29T15:54:22Z [Term] id: FYPO:0001469 name: increased steady-state intracellular calcium level following extracellular calcium stimulus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases to a greater extent than normal following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours." [PMID:21811607, PomBase:mah] synonym: "greater increase in steady-state intracellular calcium level following extracellular calcium stimulus during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001468 ! abnormal steady-state intracellular calcium level following extracellular calcium stimulus created_by: midori creation_date: 2012-08-29T15:55:25Z [Term] id: FYPO:0001470 name: normal cell population growth on tacrolimus def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus." [PomBase:mah] synonym: "normal cell population growth in presence of tacrolimus" EXACT [PomBase:mah] synonym: "normal cellular response to FK506" EXACT [CHEBI:61057] synonym: "normal cellular response to tacrolimus" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on tacrolimus" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on tacrolimus" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-29T16:03:18Z [Term] id: FYPO:0001471 name: normal cell population growth on tacrolimus during salt stress def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus, when the cell is subject to salt stress." [PomBase:mah] synonym: "normal cell population growth in presence of tacrolimus during salt stress" EXACT [PomBase:mah] synonym: "normal cell population growth on FK506 during salt stress" EXACT [CHEBI:61057] synonym: "normal cellular response to salt stress and tacrolimus" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus and salt stress" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus during salt stress" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on tacrolimus during salt stress" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on tacrolimus during salt stress" EXACT [PomBase:mah] is_a: FYPO:0001037 ! normal cell population growth during cellular response to salt stress is_a: FYPO:0001472 ! normal cell population growth on tacrolimus during osmotic stress created_by: midori creation_date: 2012-08-29T16:04:35Z [Term] id: FYPO:0001472 name: normal cell population growth on tacrolimus during osmotic stress def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus, when the cell is subject to osmotic stress." [PomBase:mah] synonym: "normal cell population growth in presence of tacrolimus during osmotic stress" EXACT [PomBase:mah] synonym: "normal cell population growth on tacrolimus and sorbitol" NARROW [PomBase:al] synonym: "normal cellular response to FK506 during osmotic stress" EXACT [CHEBI:61057] synonym: "normal cellular response to tacrolimus and osmotic stress" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus and sorbitol" RELATED [PomBase:al] synonym: "normal cellular response to tacrolimus during osmotic stress" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on tacrolimus during osmotic stress" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on tacrolimus during osmotic stress" EXACT [PomBase:mah] is_a: FYPO:0001021 ! normal cell population growth during cellular response to osmotic stress is_a: FYPO:0001470 ! normal cell population growth on tacrolimus created_by: midori creation_date: 2012-08-29T16:08:07Z [Term] id: FYPO:0001473 name: resistance to tacrolimus during salt stress def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tacrolimus than normal when the cells are subject to salt stress." [PomBase:mah] synonym: "resistance to FK506 during salt stress" EXACT [CHEBI:61057, PomBase:mah] synonym: "resistance to salt stress and tacrolimus" EXACT [PomBase:al] synonym: "resistance to tacrolimus and salt stress" EXACT [PomBase:al] synonym: "resistance to tacrolimus during salt stress during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to tacrolimus" EXACT [PomBase:mah] is_a: FYPO:0001379 ! resistance to tacrolimus created_by: midori creation_date: 2012-08-29T16:11:06Z [Term] id: FYPO:0001474 name: abnormal spindle pole body structure def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which the structure of the spindle pole body is abnormal." [PomBase:mah] comment: Note that an abnormal spindle pole body organization process may, but does not necessarily, result in abnormal spindle pole body structure. synonym: "abnormal SPB structure" EXACT [PomBase:mah] synonym: "abnormal spindle pole body structure during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2012-08-29T16:52:01Z [Term] id: FYPO:0001475 name: fragmented spindle pole body def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the spindle pole body is broken into fragments." [PomBase:mah] synonym: "fragmented SPB" EXACT [PomBase:mah] synonym: "fragmented spindle pole body during vegetative growth" EXACT [PomBase:mah] synonym: "spindle pole body fragmentation" EXACT [PomBase:vw] is_a: FYPO:0001474 ! abnormal spindle pole body structure created_by: midori creation_date: 2012-08-29T16:52:11Z [Term] id: FYPO:0001476 name: abnormal guanosine-diphosphatase activity def: "A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is abnormal." [PomBase:mah] synonym: "abnormal GDPase activity" EXACT [GO:0004382, PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-08-30T11:37:58Z [Term] id: FYPO:0001477 name: decreased guanosine-diphosphatase activity def: "A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is decreased." [PomBase:mah] synonym: "decreased GDPase activity" EXACT [GO:0004382, PomBase:mah] synonym: "reduced guanosine-diphosphatase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001476 ! abnormal guanosine-diphosphatase activity created_by: midori creation_date: 2012-08-30T11:38:10Z [Term] id: FYPO:0001478 name: increased guanosine-diphosphatase activity def: "A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is increased." [PomBase:mah] synonym: "increased GDPase activity" EXACT [GO:0004382, PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001476 ! abnormal guanosine-diphosphatase activity created_by: midori creation_date: 2012-08-30T11:38:17Z [Term] id: FYPO:0001479 name: abnormal alpha,alpha-trehalase activity def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is abnormal." [PomBase:mah] synonym: "abnormal neutral trehalase activity" EXACT [PMID:9729425, PomBase:mah] synonym: "abnormal trehalase activity" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-08-30T11:47:38Z [Term] id: FYPO:0001480 name: normal alpha,alpha-trehalase activity def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal neutral trehalase activity" EXACT [PMID:9729425, PomBase:mah] synonym: "normal trehalase activity" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0000660 ! normal catalytic activity created_by: midori creation_date: 2012-08-30T12:05:18Z [Term] id: FYPO:0001481 name: alpha,alpha-trehalase activity increase abolished during cellular response to nutrient def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a nutrient stimulus." [PomBase:mah] synonym: "absent increase in trehalase activity following nutrient stimulus" EXACT [PomBase:al] synonym: "neutral trehalase activity increase abolished during cellular response to nutrient" EXACT [PMID:9729425, PomBase:mah] synonym: "trehalase activity increase abolished during cellular response to nutrient" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity is_a: FYPO:0001484 ! abnormal cellular response to nutrient created_by: midori creation_date: 2012-08-30T12:11:19Z [Term] id: FYPO:0001482 name: alpha,alpha-trehalase activity increase abolished during cellular response to heat def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a heat stimulus." [PomBase:mah] synonym: "absent increase in trehalase activity in response to high temperature" EXACT [PomBase:al] synonym: "neutral trehalase activity increase abolished during cellular response to heat" EXACT [PMID:9729425, PomBase:mah] synonym: "trehalase activity increase abolished during cellular response to heat" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0000212 ! abnormal cellular response to heat is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2012-08-30T12:15:03Z [Term] id: FYPO:0001483 name: normal alpha,alpha-trehalase activity increase during cellular response to oxidative stress def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity increases normally (i.e. as in wild type) as a result of oxidative stress." [PomBase:mah] synonym: "normal increase in trehalase activity in response to oxidative stress" EXACT [PomBase:al] synonym: "normal neutral trehalase activity increase during cellular response to oxidative stress" EXACT [PMID:9729425, PomBase:mah] synonym: "normal trehalase activity increase during cellular response to oxidative stress" BROAD [GO:0004555, GO:0015927] is_a: FYPO:0001480 ! normal alpha,alpha-trehalase activity is_a: FYPO:0001485 ! normal cellular response to oxidative stress created_by: midori creation_date: 2012-08-30T12:18:52Z [Term] id: FYPO:0001484 name: abnormal cellular response to nutrient def: "A chemical response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a nutrient is abnormal." [PomBase:mah] synonym: "abnormal cellular response to nutrient during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001342 ! cellular response phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-08-30T13:01:53Z [Term] id: FYPO:0001485 name: normal cellular response to oxidative stress def: "A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to oxidative stress is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular response to oxidative stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000968 ! normal cellular response to stress is_a: FYPO:0001318 ! normal cellular response to chemical stimulus during vegetative growth created_by: midori creation_date: 2012-08-30T13:03:23Z [Term] id: FYPO:0001486 name: normal RNA level during cellular response to salt stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal mRNA level during cellular response to salt stress" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to salt stress" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to salt stress during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-08-30T13:08:09Z [Term] id: FYPO:0001487 name: normal RNA level during cellular response to heat def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to heat is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "normal mRNA level during cellular response to heat" NARROW [PomBase:mah] synonym: "normal RNA accumulation during cellular response to heat" RELATED [PomBase:mah] synonym: "normal RNA level during cellular response to heat during vegetative growth" EXACT [PomBase:mah] synonym: "normal RNA level during cellular response to high temperature" EXACT [PomBase:al] is_a: FYPO:0001317 ! normal RNA level during vegetative growth created_by: midori creation_date: 2012-08-30T13:09:03Z [Term] id: FYPO:0001488 name: sensitive to protamine sulfate def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to protamine sulfate. A protamine is any of a group of simple proteins that yield basic amino acids on hydrolysis, and forms a complex with heparin. Cells stop growing (and may die) at a concentration of protamine sulfate that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to protamine sulfate" EXACT [PomBase:mah] synonym: "sensitive to protamine sulfate during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-08-30T13:32:12Z [Term] id: FYPO:0001489 name: inviable vegetative cell def: "A cell phenotype in which a cell is inviable in the phase of the life cycle during which wild type cells undergo vegetative growth." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "essential in vegetative cell" RELATED [PomBase:mah] synonym: "inviable cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000049 ! inviable cell is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-30T13:59:02Z [Term] id: FYPO:0001490 name: elongated inviable vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable and longer than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell during vegetative growth" EXACT [PomBase:mah] synonym: "essential; elongated vegetative cell" RELATED [PomBase:mah] is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000049 ! inviable cell created_by: midori creation_date: 2012-08-30T14:08:27Z [Term] id: FYPO:0001491 name: viable vegetative cell def: "A cell phenotype in which a vegetatively growing cell is viable." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000124 ! viable cell is_a: FYPO:0001320 ! vegetative cell phenotype created_by: midori creation_date: 2012-08-30T14:12:48Z [Term] id: FYPO:0001492 name: elongated viable vegetative cell def: "A cell morphology phenotype in which a vegetative cell is viable and longer than normal." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated viable cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001122 ! elongated vegetative cell is_a: FYPO:0001491 ! viable vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000124 ! viable cell created_by: midori creation_date: 2012-08-30T14:17:56Z [Term] id: FYPO:0001493 name: inviable elongated multinucleate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, longer than normal, and contains more than one nucleus apiece." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable multinucleate cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate inviable vegetative cell" EXACT [PomBase:mah] synonym: "essential; elongated multinucleate vegetative cell" RELATED [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate cell is_a: FYPO:0001490 ! elongated inviable vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000049 ! inviable cell relationship: has_part FYPO:0000061 ! multinucleate created_by: midori creation_date: 2012-08-30T14:27:16Z [Term] id: FYPO:0001494 name: elongated multiseptate inviable vegetative cell def: "A cell morphology phenotype in which a vegetative cell is inviable, longer than normal, and contains more than one septum." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable multiseptate cell during vegetative growth" EXACT [PomBase:mah] synonym: "essential; elongated multiseptate vegetative cell" RELATED [PomBase:mah] is_a: FYPO:0000223 ! elongated multiseptate cells is_a: FYPO:0001490 ! elongated inviable vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000049 ! inviable cell relationship: has_part FYPO:0000118 ! multiseptate created_by: midori creation_date: 2012-08-30T14:30:53Z [Term] id: FYPO:0001495 name: viable elongated multinucleate vegetative cell def: "A cell morphology phenotype in which a vegetative cell is viable, longer than normal, and contains more than one nucleus." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated multinucleate viable cell during vegetative growth" EXACT [PomBase:mah] synonym: "elongated multinucleate viable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0000133 ! elongated multinucleate cell is_a: FYPO:0001492 ! elongated viable vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000061 ! multinucleate relationship: has_part FYPO:0000124 ! viable cell created_by: midori creation_date: 2012-08-30T14:32:23Z [Term] id: FYPO:0001496 name: elongated multiseptate viable vegetative cell def: "A cell morphology phenotype in which a vegetative cell is viable, longer than normal, and contain more than one septum." [PomBase:mah] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "elongated viable multiseptate cell during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000223 ! elongated multiseptate cells is_a: FYPO:0001492 ! elongated viable vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000118 ! multiseptate relationship: has_part FYPO:0000124 ! viable cell created_by: midori creation_date: 2012-08-30T14:32:53Z [Term] id: FYPO:0001497 name: elongated inviable vegetative cell with mitotic cell cycle arrest in S phase def: "A cell morphology phenotype in which a vegetative cell is inviable and longer than normal, and progress through the mitotic cell cycle is arrested in S phase." [PomBase:mah] comment: A population of cells with this phenotype usually shows a marginal increase in cell number before all cells die. Cells arrested in S phase typically have more than 1C, but less than 2C, DNA content. Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "elongated inviable cell with mitotic cell cycle arrest in S phase during vegetative growth" EXACT [PomBase:mah] synonym: "essential; elongated vegetative cell with mitotic cell cycle arrest in S phase" RELATED [PomBase:mah] synonym: "mitotic cell cycle arrest in S-phase with elongated inviable cell" EXACT [PomBase:vw] synonym: "mitotic S-phase arrested elongated inviable vegetative cell" EXACT [PomBase:mah] is_a: FYPO:0001490 ! elongated inviable vegetative cell relationship: has_part FYPO:0000017 ! elongated cell relationship: has_part FYPO:0000049 ! inviable cell relationship: has_part FYPO:0000611 ! mitotic cell cycle arrest in S phase created_by: midori creation_date: 2012-08-30T14:37:31Z [Term] id: FYPO:0001498 name: sensitive to cytochalasin B def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cytochalasin B. Cells stop growing (and may die) at a concentration of cytochalasin B that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to cytochalasin B" EXACT [PomBase:mah] synonym: "sensitive to cytochalasin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-08-30T15:23:47Z [Term] id: FYPO:0001499 name: resistance to cytochalasin B def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cytochalasin B than normal." [PomBase:mah] synonym: "resistance to cytochalasin B during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-08-30T15:24:42Z [Term] id: FYPO:0001500 name: normal cell population growth on cytochalasin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cytochalasin B." [PomBase:mah] synonym: "normal cell population growth in presence of cytochalasin B" EXACT [PomBase:mah] synonym: "normal cellular response to cytochalasin B" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on cytochalasin B" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on cytochalasin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-08-30T15:25:41Z [Term] id: FYPO:0001501 name: sensitive to brefeldin A def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to brefeldin A. Cells stop growing (and may die) at a concentration of brefeldin A that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to brefeldin A" EXACT [PomBase:mah] synonym: "sensitive to BFA" EXACT [PomBase:mah] synonym: "sensitive to brefeldin A during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-08-30T15:29:30Z [Term] id: FYPO:0001502 name: increased cellular trehalose level during cellular response to osmotic stress def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal when the cell is subject to osmotic stress." [PomBase:mah] synonym: "increased cellular trehalose level during vegetative growth and during cellular response to osmotic stress" EXACT [PomBase:mah] synonym: "increased cellular trehalose level in response to osmotic stress" EXACT [PomBase:al] synonym: "increased trehalose accumulation during cellular response to osmotic stress" RELATED [PomBase:mah] is_a: FYPO:0001444 ! increased cellular trehalose level created_by: midori creation_date: 2012-08-31T14:27:51Z [Term] id: FYPO:0001503 name: decreased alpha,alpha-trehalase activity during sporulation def: "A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during sporulation." [PomBase:mah] synonym: "decreased neutral trehalase activity during sporulation" EXACT [PMID:9729425, PomBase:mah] synonym: "decreased trehalase activity during sporulation" BROAD [GO:0004555, GO:0015927] synonym: "reduced alpha,alpha-trehalase activity during sporulation" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001479 ! abnormal alpha,alpha-trehalase activity created_by: midori creation_date: 2012-08-31T14:29:44Z [Term] id: FYPO:0001504 name: decreased cellular trehalose level during sporulation def: "A cell phenotype in which the amount of trehalose measured in a cell is lower than normal during sporulation." [PomBase:mah] synonym: "decreased cellular trehalose accumulation during sporulation" RELATED [PomBase:mah] synonym: "reduced cellular trehalose level during sporulation" EXACT [PomBase:mah] is_a: FYPO:0001447 ! decreased cellular trehalose level created_by: midori creation_date: 2012-08-31T14:31:44Z [Term] id: FYPO:0001505 name: increased cellular phosphatidylserine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular phosphatidyl-L-serine level" EXACT [CHEBI:18303] synonym: "increased cellular phosphatidylserine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular PS level" EXACT [PomBase:mah] synonym: "increased phosphatidylserine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001288 ! increased phospholipid level created_by: midori creation_date: 2012-08-31T14:45:54Z [Term] id: FYPO:0001506 name: normal cellular phosphatidylcholine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylcholine measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular PC level" EXACT [PomBase:mah] synonym: "normal cellular phosphatidylcholine accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylcholine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001543 ! normal cellular phosphorus level created_by: midori creation_date: 2012-08-31T14:48:33Z [Term] id: FYPO:0001507 name: normal cellular phosphatidylinositol level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular phosphatidylinositol accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphatidylinositol level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular PI level" EXACT [CHEBI:28874, PomBase:mah] is_a: FYPO:0001543 ! normal cellular phosphorus level created_by: midori creation_date: 2012-08-31T14:49:23Z [Term] id: FYPO:0001508 name: abolished protein localization to chromatin during vegetative growth def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abolished in the vegetative growth phase of the life cycle." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to chromatin during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to chromatin during vegetative growth abolished" EXACT [PomBase:mah] is_a: FYPO:0000452 ! abnormal protein localization to chromatin during vegetative growth is_a: FYPO:0001179 ! protein localization abolished during vegetative growth is_a: FYPO:0001678 ! abolished protein localization to chromatin created_by: midori creation_date: 2012-09-04T17:02:28Z [Term] id: FYPO:0001509 name: normal protein localization to chromatin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to chromatin" EXACT [PomBase:mah] synonym: "normal protein localization to chromatin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization created_by: midori creation_date: 2012-09-04T17:04:49Z [Term] id: FYPO:0001510 name: viable vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype in which a cell is viable, cell shape is altered, and cell size remains normal, in the vegetative growth phase of the life cycle." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'viable cell population' (FYPO:0002058) or one of its descendants. synonym: "viable lumpy cell" RELATED [PomBase:vw] synonym: "viable, abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001121 ! vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0001491 ! viable vegetative cell relationship: has_part FYPO:0001124 ! normal cell size relationship: has_part FYPO:0001126 ! abnormal cell shape relationship: has_part FYPO:0001491 ! viable vegetative cell created_by: midori creation_date: 2012-09-13T10:47:20Z [Term] id: FYPO:0001511 name: inviable vegetative cell, abnormal cell shape, normal cell size def: "A cell phenotype in which a cell is inviable, cell shape is altered, and cell size remains normal, in the vegetative growth phase of the life cycle." [PomBase:mah, PomBase:vw] comment: Note that if you have done an experiment that assays the viability of a population of cells, such as looking at colony growth or growth in liquid culture, you should also annotate to 'inviable cell population' (FYPO:0002059) or one of its descendants. synonym: "inviable lumpy cell" RELATED [PomBase:vw] synonym: "inviable, abnormal cell shape, normal cell size during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001121 ! vegetative cell, abnormal cell shape, normal cell size is_a: FYPO:0001489 ! inviable vegetative cell relationship: has_part FYPO:0001124 ! normal cell size relationship: has_part FYPO:0001126 ! abnormal cell shape relationship: has_part FYPO:0001489 ! inviable vegetative cell created_by: midori creation_date: 2012-09-13T10:52:33Z [Term] id: FYPO:0001512 name: branched, elongated cell def: "A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched, and therefore septated, and longer than normal." [PomBase:mah] synonym: "branched, elongated cell during vegetative growth" EXACT [PomBase:mah] synonym: "branched, elongated, septated cell" EXACT [PomBase:jh, PomBase:mah, PomBase:vw] synonym: "branched, long, septated cell" EXACT [PomBase:vw] is_a: FYPO:0000015 ! branched cell is_a: FYPO:0001122 ! elongated vegetative cell relationship: has_part FYPO:0000015 ! branched cell relationship: has_part FYPO:0000017 ! elongated cell created_by: midori creation_date: 2012-09-13T10:58:38Z [Term] id: FYPO:0001513 name: normal mitotic sister chromatid segregation def: "A cellular process phenotype in which mitotic sister chromatid segregation is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid segregation is the entire process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle." [GO:0000070, PomBase:mah] synonym: "normal mitotic chromosome segregation" EXACT [PomBase:mah] synonym: "normal mitotic sister chromatid segregation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001007 ! normal mitosis created_by: midori creation_date: 2012-09-13T11:23:11Z [Term] id: FYPO:0001514 name: decreased protein localization to nucleus def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to nucleus" EXACT [GO:0034504, PomBase:mah] synonym: "decreased protein localization to nucleus during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus" EXACT [PomBase:mah] is_a: FYPO:0001129 ! abnormal protein localization to nucleus created_by: midori creation_date: 2012-09-13T11:39:44Z [Term] id: FYPO:0001515 name: abnormal telomere tethering at nuclear periphery def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery is abnormal." [PomBase:mah] synonym: "abnormal telomere anchoring at nuclear periphery" EXACT [PomBase:vw] synonym: "abnormal telomere tethering at nuclear periphery during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001337 ! localization phenotype during vegetative growth is_a: FYPO:0001362 ! abnormal cellular process during vegetative growth created_by: midori creation_date: 2012-09-13T11:46:25Z [Term] id: FYPO:0001516 name: resistance to mercury def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of mercury ions than normal." [PomBase:mah] synonym: "resistance to mercury during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to mercury ion" EXACT [PomBase:mah] synonym: "resistant to mercury" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-09-13T13:16:13Z [Term] id: FYPO:0001517 name: resistance to aluminium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aluminium ions than normal." [PomBase:mah] synonym: "resistance to aluminium cation" EXACT [CHEBI:63062] synonym: "resistance to aluminium during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to aluminum" EXACT [PomBase:mah] synonym: "resistant to aluminium" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-09-13T13:22:53Z [Term] id: FYPO:0001518 name: resistance to diethyl maleate def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of diethyl maleate than normal." [PomBase:mah] comment: Note that diethyl maleate should not be written without a space, as diethylmaleate is a different compound. synonym: "resistance to DEM" EXACT [PomBase:al] synonym: "resistance to diethyl maleate during vegetative growth" EXACT [PomBase:mah] synonym: "resistant to diethyl maleate" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-09-13T13:41:57Z [Term] id: FYPO:0001519 name: abnormal gamma-glutamyltransferase activity def: "A molecular function phenotype in which the observed rate of gamma-glutamyltransferase activity is abnormal." [PomBase:mah] synonym: "abnormal gamma-glutamyl transpeptidase activity" EXACT [GO:0003840, PomBase:mah] synonym: "abnormal GGT activity" BROAD [PomBase:al, PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-09-13T13:53:10Z [Term] id: FYPO:0001520 name: increased gamma-glutamyltransferase activity def: "A molecular function phenotype in which the observed rate of gamma-glutamyltransferase activity is increased." [PomBase:mah] synonym: "increased gamma-glutamyl transpeptidase activity" EXACT [GO:0003840, PomBase:mah] synonym: "increased GGT activity" BROAD [PomBase:al, PomBase:mah] is_a: FYPO:0000662 ! increased catalytic activity is_a: FYPO:0001519 ! abnormal gamma-glutamyltransferase activity created_by: midori creation_date: 2012-09-13T13:53:17Z [Term] id: FYPO:0001521 name: increased cellular glutathione level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glutathione level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular GSH level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular L-gamma-glutamyl-L-cysteinylglycine level" EXACT [CHEBI:16856] synonym: "increased cellular reduced glutathione level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased glutathione accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T14:02:16Z [Term] id: FYPO:0001522 name: normal cell population growth on caffeine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing caffeine." [PomBase:mah] synonym: "normal cell population growth in presence of caffeine" EXACT [PomBase:mah] synonym: "normal cellular response to caffeine" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on caffeine" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on caffeine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-13T14:06:29Z [Term] id: FYPO:0001523 name: normal cell population growth on leptomycin B def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing leptomycin B." [PomBase:mah] synonym: "normal cell population growth in presence of leptomycin B" EXACT [PomBase:mah] synonym: "normal cellular response to leptomycin B" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on leptomycin B" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on leptomycin B" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-13T14:09:56Z [Term] id: FYPO:0001524 name: resistance to L-thialysine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-thialysine than normal." [PomBase:mah] synonym: "resistance to L-thialysine during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to thialysine" BROAD [PomBase:mah] synonym: "resistant to L-thialysine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-09-13T14:36:42Z [Term] id: FYPO:0001525 name: sensitive to L-thialysine def: "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to L-thialysine. Cells stop growing (and may die) at a concentration of L-thialysine that allows wild type cells to grow." [PomBase:mah] synonym: "hypersensitive to L-thialysine" EXACT [PomBase:mah] synonym: "sensitive to L-thialysine during vegetative growth" EXACT [PomBase:mah] synonym: "sensitive to thialysine" BROAD [PomBase:mah] is_a: FYPO:0000127 ! increased sensitivity to chemical created_by: midori creation_date: 2012-09-13T14:43:00Z [Term] id: FYPO:0001526 name: normal cell population growth on L-thialysine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing L-thialysine." [PomBase:mah] synonym: "normal cell population growth in presence of L-thialysine" EXACT [PomBase:mah] synonym: "normal cell population growth on thialysine" BROAD [PomBase:mah] synonym: "normal cellular response to L-thialysine" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on L-thialysine" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on L-thialysine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-13T14:46:44Z [Term] id: FYPO:0001527 name: normal GTP binding def: "A molecular function phenotype in which occurrence of GTP binding by a mutated gene product is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000706 ! normal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-09-13T14:53:26Z [Term] id: FYPO:0001528 name: abnormal GTP binding def: "A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is abnormal." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds GTP differently from wild type, or that a mutation in one gene affects GTP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. is_a: FYPO:0000707 ! abnormal molecular function is_a: FYPO:0001092 ! binding phenotype created_by: midori creation_date: 2012-09-13T14:54:29Z [Term] id: FYPO:0001529 name: decreased GTP binding def: "A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is decreased." [PomBase:mah] comment: This term can mean that the mutated gene product itself binds GTP less than wild type, or that a mutation in one gene decreases GTP binding by a second gene product. When using this term, it is therefore recommended to note the specific protein(s) affected. synonym: "reduced GTP binding" EXACT [PomBase:mah] is_a: FYPO:0001528 ! abnormal GTP binding created_by: midori creation_date: 2012-09-13T14:55:25Z [Term] id: FYPO:0001530 name: abnormal GTPase activity def: "A molecular function phenotype in which the observed rate of GTPase activity is abnormal." [PomBase:mah] is_a: FYPO:0000661 ! abnormal catalytic activity created_by: midori creation_date: 2012-09-13T15:01:53Z [Term] id: FYPO:0001531 name: decreased GTPase activity def: "A molecular function phenotype in which the observed rate of GTPase activity is decreased." [PomBase:mah] synonym: "reduced GTPase activity" EXACT [PomBase:mah] is_a: FYPO:0000663 ! decreased catalytic activity is_a: FYPO:0001530 ! abnormal GTPase activity created_by: midori creation_date: 2012-09-13T15:02:01Z [Term] id: FYPO:0001532 name: normal duration of mitotic S phase def: "A cell cycle phenotype in the duration of S phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type)." [PomBase:mah] is_a: FYPO:0000411 ! normal cell cycle progression created_by: midori creation_date: 2012-09-13T15:28:30Z [Term] id: FYPO:0001533 name: sensitive to zinc starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zinc starvation." [PomBase:mah] synonym: "hypersensitive to zinc starvation" EXACT [PomBase:mah] synonym: "sensitive to zinc ion starvation" EXACT [PomBase:mah] synonym: "sensitive to zinc starvation during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000304 ! sensitive to stress is_a: FYPO:0001339 ! abnormal cellular response to starvation during vegetative growth created_by: midori creation_date: 2012-09-13T15:35:17Z [Term] id: FYPO:0001534 name: decreased cellular zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular zinc ion level" EXACT [PomBase:mah] synonym: "decreased cellular zinc level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased zinc accumulation" RELATED [PomBase:al] synonym: "reduced cellular zinc level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T15:43:51Z [Term] id: FYPO:0001535 name: normal cellular zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular zinc accumulation" RELATED [PomBase:mah] synonym: "normal cellular zinc ion level" EXACT [PomBase:mah] synonym: "normal cellular zinc level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T15:48:08Z [Term] id: FYPO:0001536 name: normal cellular copper level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of copper ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular copper accumulation" RELATED [PomBase:mah] synonym: "normal cellular copper ion level" EXACT [PomBase:mah] synonym: "normal cellular copper level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:07:14Z [Term] id: FYPO:0001537 name: normal cellular iron level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of iron ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular iron accumulation" RELATED [PomBase:mah] synonym: "normal cellular iron ion level" EXACT [PomBase:mah] synonym: "normal cellular iron level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:07:47Z [Term] id: FYPO:0001538 name: normal cellular potassium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of potassium ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular potassium accumulation" RELATED [PomBase:mah] synonym: "normal cellular potassium ion level" EXACT [PomBase:mah] synonym: "normal cellular potassium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:08:23Z [Term] id: FYPO:0001539 name: normal cellular magnesium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of magnesium ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular magnesium accumulation" RELATED [PomBase:mah] synonym: "normal cellular magnesium ion level" EXACT [PomBase:mah] synonym: "normal cellular magnesium level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:14:33Z [Term] id: FYPO:0001540 name: normal cellular manganese level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of manganese ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular manganese accumulation" RELATED [PomBase:mah] synonym: "normal cellular manganese ion level" EXACT [PomBase:mah] synonym: "normal cellular manganese level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:08:54Z [Term] id: FYPO:0001541 name: normal cellular molybdenum level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of molybdenum ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular molybdenum accumulation" RELATED [PomBase:mah] synonym: "normal cellular molybdenum ion level" EXACT [PomBase:mah] synonym: "normal cellular molybdenum level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:09:45Z [Term] id: FYPO:0001542 name: normal cellular nickel level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nickel ion measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular nickel accumulation" RELATED [PomBase:mah] synonym: "normal cellular nickel ion level" EXACT [PomBase:mah] synonym: "normal cellular nickel level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:10:13Z [Term] id: FYPO:0001543 name: normal cellular phosphorus level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphorus measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular phosphorus accumulation" RELATED [PomBase:mah] synonym: "normal cellular phosphorus level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:11:42Z [Term] id: FYPO:0001544 name: normal cellular sulfur level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfur measured in a cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular sulfur accumulation" RELATED [PomBase:mah] synonym: "normal cellular sulfur level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular sulphur level" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-13T16:12:10Z [Term] id: FYPO:0001545 name: normal cell population growth on L-canavanine def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing L-canavanine." [PomBase:mah] synonym: "normal cell population growth in presence of L-canavanine" EXACT [PomBase:mah] synonym: "normal cell population growth on canavanine" BROAD [PomBase:mah] synonym: "normal cellular response to L-canavanine" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on L-canavanine" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on L-canavanine" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-14T14:23:13Z [Term] id: FYPO:0001546 name: decreased RNA level during cellular response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion is lower than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "decreased mRNA level during cellular response to zinc ion" NARROW [PomBase:mah] synonym: "decreased RNA accumulation during cellular response to zinc ion" RELATED [PomBase:mah] synonym: "decreased RNA level during cellular response to zinc" EXACT [GO:0071456] synonym: "decreased RNA level during cellular response to zinc ion during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001117 ! decreased RNA level during vegetative growth created_by: midori creation_date: 2012-09-14T14:26:22Z [Term] id: FYPO:0001547 name: increased RNA level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion starvation is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mRNA level during cellular response to zinc ion starvation" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased RNA level during cellular response to zinc starvation" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-09-14T14:28:30Z [Term] id: FYPO:0001548 name: altered protein level during cellular response to hydrogen peroxide def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to hydrogen peroxide. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "abnormal protein level during cellular response to hydrogen peroxide" EXACT [PomBase:mah] synonym: "altered cellular protein level during cellular response to hydrogen peroxide during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:32:40Z [Term] id: FYPO:0001549 name: altered protein level during cellular response to hypoxia def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to hypoxia. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "abnormal protein level during cellular response to hypoxia" EXACT [PomBase:mah] synonym: "altered cellular protein level during cellular response to hypoxia during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:34:37Z [Term] id: FYPO:0001550 name: altered protein level during cellular response to zinc ion def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to zinc ions. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "abnormal protein level during cellular response to zinc ion" EXACT [PomBase:mah] synonym: "altered cellular protein level during cellular response to zinc ion during vegetative growth" EXACT [PomBase:mah] synonym: "altered protein level during cellular response to zinc" EXACT [PomBase:mah] is_a: FYPO:0001325 ! altered protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:36:13Z [Term] id: FYPO:0001551 name: increased protein level during cellular response to zinc ion starvation def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to zinc ion starvation is higher than normal. Total protein or a specific protein may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. synonym: "increased protein accumulation during cellular response to zinc ion starvation" RELATED [PomBase:mah] synonym: "increased protein level during cellular response to zinc ion starvation during vegetative growth" EXACT [PomBase:mah] synonym: "increased protein level during cellular response to zinc starvation" EXACT [GO:0071453] is_a: FYPO:0001327 ! increased protein level during vegetative growth created_by: midori creation_date: 2012-09-14T14:37:37Z [Term] id: FYPO:0001552 name: increased cellular zinc level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular zinc ion level" EXACT [PomBase:mah] synonym: "increased cellular zinc level during vegetative growth" EXACT [PomBase:mah] synonym: "increased zinc accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T14:42:05Z [Term] id: FYPO:0001553 name: abnormal RNA processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is abnormal. RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." [GO:0006396, PomBase:mah] synonym: "abnormal RNA processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000142 ! gene expression phenotype is_a: FYPO:0000294 ! RNA metabolism phenotype is_a: FYPO:0001363 ! abnormal metabolic process during vegetative growth created_by: midori creation_date: 2012-09-14T15:07:19Z [Term] id: FYPO:0001554 name: abnormal tRNA processing def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA processing is abnormal. tRNA processing is the conversion a primary tRNA transcript into a mature tRNA molecules." [GO:0008033, PomBase:mah] synonym: "abnormal tRNA processing during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001553 ! abnormal RNA processing created_by: midori creation_date: 2012-09-14T15:10:20Z [Term] id: FYPO:0001555 name: formation of abnormal tRNA processing intermediates def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the intermediate RNAs formed during tRNA processing differ from wild type in size." [PomBase:al, PomBase:mah] comment: Note that the mature tRNA may be of normal or abnormal size. synonym: "abnormal tRNA maturation intermediates" EXACT [PomBase:al] synonym: "formation of abnormal tRNA processing intermediates during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001554 ! abnormal tRNA processing created_by: midori creation_date: 2012-09-14T15:12:24Z [Term] id: FYPO:0001556 name: excess nuclear envelope present def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which cells contain more nuclear envelope than normal. Excess nuclear envelopes may take the form of intranuclear membrane stacks or small cytoplasmic spheres that are attached to the nucleus, have double lipid bilayer membranes, and may structures resembling nuclear pores." [PMID:22156749, PomBase:mah] synonym: "excess nuclear envelope present during vegetative growth" EXACT [PomBase:mah] synonym: "increased nuclear envelope proliferation" RELATED [PMID:22156749, PomBase:vw] synonym: "nuclear envelope present in greater amount" EXACT [PomBase:mah] is_a: FYPO:0000769 ! abnormal nuclear envelope morphology created_by: midori creation_date: 2012-09-14T15:22:32Z [Term] id: FYPO:0001557 name: resistance to ethionine def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethionine than normal." [PomBase:mah] comment: Note that a racemic mixture of D and L enantiomers of ethionine is usually used to test sensitivity or resistance. synonym: "resistance to DL-ethionine" RELATED [PomBase:mah] synonym: "resistance to ethionine during vegetative growth" EXACT [PomBase:mah] synonym: "resistance to S-ethylhomocysteine" EXACT [CHEBI:68662, PomBase:mah] synonym: "resistant to ethionine" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-09-14T16:15:57Z [Term] id: FYPO:0001558 name: decreased methionine import def: "A cellular process phenotype in which the import of methionine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased methionine import into cell" EXACT [PomBase:al] synonym: "decreased methionine transport into cell" EXACT [PomBase:al] synonym: "decreased methionine uptake" EXACT [GO:0036233] synonym: "reduced methionine import" EXACT [PomBase:mah] synonym: "reduced methionine uptake" EXACT [PomBase:vw] is_a: FYPO:0001058 ! decreased amino acid import created_by: midori creation_date: 2012-09-14T16:32:14Z [Term] id: FYPO:0001559 name: normal methionine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methionine import into the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal methionine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal methionine import into cell" EXACT [PomBase:al] synonym: "normal methionine uptake" EXACT [GO:0043091] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-14T16:34:42Z [Term] id: FYPO:0001560 name: decreased cellular threonine level alt_id: FYPO:0001614 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-threonine level" EXACT [PomBase:mah] synonym: "decreased cellular threonine level" EXACT [PomBase:mah] synonym: "decreased cellular threonine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of threonine in cell" EXACT [PomBase:mah] synonym: "decreased threonine accumulation" RELATED [PomBase:al] synonym: "reduced cellular threonine level" EXACT [PomBase:mah] synonym: "reduced level of threonine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:44:29Z [Term] id: FYPO:0001561 name: decreased cellular citrulline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-citrulline measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular citrulline level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-citrulline level" EXACT [PomBase:mah] synonym: "decreased citrulline accumulation" RELATED [PomBase:al] synonym: "reduced cellular citrulline level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:45:19Z [Term] id: FYPO:0001562 name: decreased cellular histidine level alt_id: FYPO:0001620 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-histidine level" EXACT [PomBase:mah] synonym: "decreased histidine accumulation" RELATED [PomBase:al] synonym: "reduced cellular histidine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:46:05Z [Term] id: FYPO:0001563 name: decreased cellular glutamate level alt_id: FYPO:0001615 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular glutamate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular glutamic acid level" RELATED [PomBase:mah] synonym: "decreased cellular L-glutamate level" EXACT [PomBase:mah] synonym: "decreased glutamate accumulation" RELATED [PomBase:al] synonym: "reduced cellular glutamate level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:46:41Z [Term] id: FYPO:0001564 name: decreased cellular ornithine level alt_id: FYPO:0001618 def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-ornithine level" EXACT [PomBase:mah] synonym: "decreased cellular ornithine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased ornithine accumulation" RELATED [PomBase:al] synonym: "reduced cellular ornithine level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:47:41Z [Term] id: FYPO:0001565 name: increased cellular threonine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-threonine level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular threonine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased threonine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:48:22Z [Term] id: FYPO:0001566 name: increased cellular citrulline level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-citrulline measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular citrulline level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-citrulline level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased citrulline accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:49:05Z [Term] id: FYPO:0001567 name: increased cellular histidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-histidine level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased histidine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:49:35Z [Term] id: FYPO:0001568 name: increased cellular glutamate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular glutamate level during vegetative growth" EXACT [PomBase:mah] synonym: "increased cellular L-glutamate level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased glutamate accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:50:25Z [Term] id: FYPO:0001569 name: increased cellular ornithine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in a cell is higher than normal." [PomBase:mah] synonym: "increased cellular L-ornithine level" EXACT [CHEBI:16856, PomBase:al] synonym: "increased cellular ornithine level during vegetative growth" EXACT [PomBase:mah] synonym: "increased ornithine accumulation" RELATED [PomBase:mah] is_a: FYPO:0001330 ! increased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:51:00Z [Term] id: FYPO:0001570 name: decreased cellular glutathione level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular glutathione level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular GSH level" EXACT [CHEBI:16856, PomBase:al] synonym: "decreased cellular L-gamma-glutamyl-L-cysteinylglycine level" EXACT [CHEBI:16856] synonym: "decreased cellular reduced glutathione level" EXACT [CHEBI:16856, PomBase:al] synonym: "decreased glutathione accumulation" RELATED [PomBase:mah] synonym: "reduced cellular glutathione level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-14T16:51:27Z [Term] id: FYPO:0001571 name: increased protein binding def: "A molecular function phenotype in which the binding of one protein to another occurs to a greater extent than normal." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "increased protein-protein interaction" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein binding created_by: midori creation_date: 2012-09-20T13:22:04Z [Term] id: FYPO:0001572 name: abolished cell population growth on methionine nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing L-methionine as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on methionine nitrogen source" BROAD [PomBase:mah] synonym: "abolished methionine utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on methionine nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on methionine nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2012-09-20T13:55:30Z [Term] id: FYPO:0001573 name: increased RNA level during cellular response to rapamycin def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to rapamycin is higher than normal. Total RNA or a specific RNA may be affected." [PomBase:mah] comment: Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. synonym: "increased mRNA level during cellular response to rapamycin" NARROW [PomBase:mah] synonym: "increased RNA accumulation during cellular response to rapamycin" RELATED [PomBase:mah] synonym: "increased RNA level during cellular response to rapamycin during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000825 ! increased RNA level during vegetative growth created_by: midori creation_date: 2012-09-20T14:11:44Z [Term] id: FYPO:0001574 name: abnormal bipolar mitotic spindle def: "A cellular structure phenotype in which the mitotic spindle has two poles but is otherwise structurally abnormal." [PomBase:mah] is_a: FYPO:0000338 ! abnormal mitotic spindle created_by: midori creation_date: 2012-09-20T14:36:56Z [Term] id: FYPO:0001575 name: abolished vegetative cell population growth def: "A cellular process phenotype in which vegetative cell population growth does not occur, although cells remain viable." [PomBase:mah] comment: This term's primary purpose is to organize terms beneath it in the ontology, and we recommend that it not be used for direct annotations. Please consider using one of the more specific terms, which mention carbon or nitrogen sources, to annotate each phenotype, as cells that do not grow on any media would be considered inviable. subset: qc_do_not_annotate synonym: "vegetative cell population growth abolished" EXACT [PomBase:mah] synonym: "vegetative population growth abolished" EXACT [PomBase:mah] is_a: FYPO:0001355 ! decreased vegetative cell population growth created_by: midori creation_date: 2012-09-20T14:52:12Z [Term] id: FYPO:0001576 name: abolished cell population growth on dipeptide nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing a dipeptide such as Leu-Ala as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished dipeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on dipeptide nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on dipeptide nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:01:27Z [Term] id: FYPO:0001577 name: abolished cell population growth on tetrapeptide nitrogen source def: "A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing a tetrapeptide such as Leu-Ser-Lys-Leu as the nitrogen source." [PomBase:mah] comment: Note that cell growth terms refer to growth under aerobic conditions unless stated otherwise. synonym: "abolished growth on tetrapeptide nitrogen source" BROAD [PomBase:mah] synonym: "abolished tetrapeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "abolished vegetative cell population growth on tetrapeptide nitrogen source" EXACT [PomBase:mah] synonym: "cell population growth on tetrapeptide nitrogen source abolished" EXACT [PomBase:mah] is_a: FYPO:0001575 ! abolished vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:03:18Z [Term] id: FYPO:0001578 name: normal cell population growth on dipeptide nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing a dipeptide such as Leu-Ala as the nitrogen source." [PomBase:mah] synonym: "normal dipeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "normal growth on dipeptide nitrogen source" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on dipeptide nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:07:14Z [Term] id: FYPO:0001579 name: normal cell population growth on tetrapeptide nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing a tetrapeptide such as Leu-Ser-Lys-Leu as the nitrogen source." [PomBase:mah] synonym: "normal growth on tetrapeptide nitrogen source" BROAD [PomBase:mah] synonym: "normal tetrapeptide utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "normal vegetative cell population growth on tetrapeptide nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:08:09Z [Term] id: FYPO:0001580 name: normal cell population growth on leucine nitrogen source def: "A vegetative cell population growth phenotype in which cells grow normally in a medium containing leucine as the nitrogen source." [PomBase:mah] synonym: "normal cell population growth on monomeric leucine nitrogen source" EXACT [PomBase:vw] synonym: "normal growth on leucine nitrogen source" BROAD [PomBase:mah] synonym: "normal leucine utilization" RELATED [PomBase:mah, PomBase:vw] synonym: "normal monomeric leucine utilization" RELATED [PomBase:vw] synonym: "normal vegetative cell population growth on leucine nitrogen source" EXACT [PomBase:mah] is_a: FYPO:0001319 ! normal cellular process during vegetative growth is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T15:08:58Z [Term] id: FYPO:0001581 name: vacuolated def: "A cellular structure phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are more visible (usually by microscopy) than normal. A vacuolated phenotype may be due to the presence of more vacuoles in a cell than normal, or to vacuoles located nearer the cell surface (and hence more visible) than normal." [PomBase:mah] comment: Also see 'abnormal vacuole morphology (FYPO:0000368)' and 'vacuoles present in greater numbers' (FYPO:0000952). synonym: "vacuolated during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001322 ! abnormal subcellular structure during vegetative growth created_by: midori creation_date: 2012-09-20T15:57:31Z [Term] id: FYPO:0001582 name: normal cell population growth on glutathione def: "A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing glutathione." [PomBase:mah] synonym: "normal cell population growth in presence of glutathione" EXACT [PomBase:mah] synonym: "normal cell population growth on GSH" EXACT [CHEBI:16856] synonym: "normal cell population growth on L-gamma-glutamyl-L-cysteinylglycine" EXACT [CHEBI:16856] synonym: "normal cell population growth on reduced glutathione" EXACT [CHEBI:16856] synonym: "normal cellular response to glutathione" RELATED [PomBase:al, PomBase:mah] synonym: "normal growth on glutathione" BROAD [PomBase:mah] synonym: "normal vegetative cell population growth on glutathione" EXACT [PomBase:mah] is_a: FYPO:0001357 ! normal vegetative cell population growth created_by: midori creation_date: 2012-09-20T16:02:56Z [Term] id: FYPO:0001583 name: resistance to lithium def: "An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lithium ions than normal." [PomBase:mah] synonym: "resistance to lithium during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000126 ! increased resistance to chemical created_by: midori creation_date: 2012-09-21T15:24:01Z [Term] id: FYPO:0001584 name: abnormal protein localization to cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abnormal." [PomBase:mah] comment: Encompasses both presence of proteins not normally found associated with chromatin and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abnormal protein localisation to cell tip" EXACT [GO:0034504, PomBase:mah] synonym: "abnormal protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000443 ! abnormal protein localization during vegetative growth created_by: midori creation_date: 2012-09-21T15:26:12Z [Term] id: FYPO:0001585 name: abolished protein localization to cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abolished." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "abolished protein localisation to cell tip" EXACT [PomBase:mah] synonym: "abolished protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "protein localization to cell tip abolished" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip created_by: midori creation_date: 2012-09-21T15:26:25Z [Term] id: FYPO:0001586 name: decreased protein localization to cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "decreased protein localisation to cell tip" EXACT [GO:0034504, PomBase:mah] synonym: "decreased protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] synonym: "reduced protein localization to nucleus" EXACT [PomBase:mah] is_a: FYPO:0001584 ! abnormal protein localization to cell tip created_by: midori creation_date: 2012-09-21T15:26:32Z [Term] id: FYPO:0001587 name: normal protein localization to cell tip def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type)." [PomBase:mah] comment: We recommend noting which protein(s) were used in the assay when annotating to this term. synonym: "normal protein localisation to cell tip" EXACT [PomBase:mah] synonym: "normal protein localization to cell tip during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0000644 ! normal protein localization created_by: midori creation_date: 2012-09-21T15:26:58Z [Term] id: FYPO:0001588 name: decreased lysine import during nitrogen starvation def: "A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "decreased lysine import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased lysine transport into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased lysine uptake during nitrogen starvation" EXACT [GO:0036233] synonym: "reduced lysine import during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001650 ! decreased lysine import is_a: FYPO:0001652 ! abnormal lysine import during nitrogen starvation created_by: midori creation_date: 2012-09-27T11:07:56Z [Term] id: FYPO:0001589 name: decreased glutamate import during nitrogen starvation def: "A cellular process phenotype in which the import of glutamate into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "decreased glutamate import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased glutamate transport into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "decreased glutamate uptake during nitrogen starvation" EXACT [GO:0036233] synonym: "reduced glutamate import during nitrogen starvation" EXACT [PomBase:mah] is_a: FYPO:0001647 ! abnormal glutamate import during nitrogen starvation is_a: FYPO:0001649 ! decreased glutamate import created_by: midori creation_date: 2012-09-27T11:08:38Z [Term] id: FYPO:0001590 name: decreased lysine import during vegetative growth def: "A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle." [PomBase:mah] synonym: "decreased L-lysine import during vegetative growth" NARROW [PomBase:mah] synonym: "decreased lysine import into cell during vegetative growth" EXACT [PomBase:al] synonym: "decreased lysine uptake during vegetative growth" EXACT [GO:0036232] synonym: "reduced lysine import during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001650 ! decreased lysine import is_a: FYPO:0001653 ! abnormal lysine import during vegetative growth created_by: midori creation_date: 2012-09-27T11:36:23Z [Term] id: FYPO:0001591 name: decreased histidine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of histidine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased histidine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased histidine import into cell" EXACT [PomBase:al] synonym: "decreased histidine uptake" EXACT [GO:0036232] synonym: "decreased L-histidine import" NARROW [PomBase:mah] synonym: "reduced histidine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001655 ! abnormal histidine import created_by: midori creation_date: 2012-09-27T11:37:19Z [Term] id: FYPO:0001592 name: decreased arginine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased arginine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased arginine import into cell" EXACT [PomBase:al] synonym: "decreased arginine uptake" EXACT [GO:0036232] synonym: "decreased L-arginine import" NARROW [PomBase:mah] synonym: "reduced arginine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001654 ! abnormal arginine import created_by: midori creation_date: 2012-09-27T11:59:09Z [Term] id: FYPO:0001593 name: decreased valine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of valine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-valine import" NARROW [PomBase:mah] synonym: "decreased valine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased valine import into cell" EXACT [PomBase:al] synonym: "decreased valine uptake" EXACT [GO:0036232] synonym: "reduced valine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001658 ! abnormal valine import created_by: midori creation_date: 2012-09-27T11:59:59Z [Term] id: FYPO:0001594 name: decreased asparagine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of asparagine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased asparagine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased asparagine import into cell" EXACT [PomBase:al] synonym: "decreased asparagine uptake" EXACT [GO:0036232] synonym: "decreased L-asparagine import" NARROW [PomBase:mah] synonym: "reduced asparagine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001656 ! abnormal asparagine import created_by: midori creation_date: 2012-09-27T12:00:40Z [Term] id: FYPO:0001595 name: decreased serine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of serine into the cell occurs to a lower extent than normal." [PomBase:mah] synonym: "decreased L-serine import" NARROW [PomBase:mah] synonym: "decreased serine import during vegetative growth" EXACT [PomBase:mah] synonym: "decreased serine import into cell" EXACT [PomBase:al] synonym: "decreased serine uptake" EXACT [GO:0036232] synonym: "reduced serine import" EXACT [PomBase:mah] is_a: FYPO:0001360 ! decreased amino acid import during vegetative growth is_a: FYPO:0001657 ! abnormal serine import created_by: midori creation_date: 2012-09-27T12:01:24Z [Term] id: FYPO:0001596 name: normal amino acid import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which amino acid import is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal amino acid import during vegetative growth" EXACT [PomBase:mah] synonym: "normal amino acid import into cell" EXACT [PomBase:al] synonym: "normal amino acid uptake" EXACT [GO:0043090] is_a: FYPO:0001071 ! normal transport created_by: midori creation_date: 2012-09-27T12:17:29Z [Term] id: FYPO:0001597 name: normal valine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which valine import is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal L-valine import" NARROW [PomBase:mah] synonym: "normal valine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal valine import into cell" EXACT [PomBase:al] synonym: "normal valine uptake" EXACT [PomBase:mah] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:22:29Z [Term] id: FYPO:0001598 name: normal glutamine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which glutamine import is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal glutamine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal glutamine import into cell" EXACT [PomBase:al] synonym: "normal glutamine uptake" EXACT [PomBase:mah] synonym: "normal L-glutamine import" NARROW [PomBase:mah] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:23:11Z [Term] id: FYPO:0001599 name: normal asparagine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which asparagine import is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal asparagine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal asparagine import into cell" EXACT [PomBase:al] synonym: "normal asparagine uptake" EXACT [PomBase:mah] synonym: "normal L-asparagine import" NARROW [PomBase:mah] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:23:36Z [Term] id: FYPO:0001600 name: normal isoleucine import def: "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which isoleucine import is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal isoleucine import during vegetative growth" EXACT [PomBase:mah] synonym: "normal isoleucine import into cell" EXACT [PomBase:al] synonym: "normal isoleucine uptake" EXACT [PomBase:mah] synonym: "normal L-isoleucine import" NARROW [PomBase:mah] is_a: FYPO:0001596 ! normal amino acid import created_by: midori creation_date: 2012-09-27T12:24:12Z [Term] id: FYPO:0001601 name: altered level of substance in vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole differs from normal." [PomBase:mah] synonym: "abnormal level of substance in vacuole" EXACT [PomBase:mah] synonym: "abnormal level of substance in vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "abnormal vacuolar level of substance" EXACT [PomBase:mah] synonym: "altered vacuolar level of substance" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:06:05Z [Term] id: FYPO:0001602 name: decreased level of substance in vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of substance in vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar level of substance" EXACT [PomBase:mah] synonym: "reduced level of substance in vacuole" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001601 ! altered level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:07:26Z [Term] id: FYPO:0001603 name: normal level of substance in vacuole def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of substance in vacuole during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar level of substance" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-09-27T13:07:41Z [Term] id: FYPO:0001604 name: altered level of substance in cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol differs from normal." [PomBase:mah] synonym: "abnormal cytosolic level of substance" EXACT [PomBase:mah] synonym: "abnormal level of substance in cytosol" EXACT [PomBase:mah] synonym: "abnormal level of substance in cytosol during vegetative growth" EXACT [PomBase:mah] synonym: "altered cytosolic level of substance" EXACT [PomBase:mah] is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth is_a: FYPO:0001323 ! altered level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:17:34Z [Term] id: FYPO:0001605 name: decreased level of substance in cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is lower than normal." [PomBase:mah] synonym: "decreased cytosolic level of substance" EXACT [PomBase:mah] synonym: "decreased level of substance in cytosol during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of substance in cytosol" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth is_a: FYPO:0001604 ! altered level of substance in cytosol created_by: midori creation_date: 2012-09-27T13:18:39Z [Term] id: FYPO:0001606 name: normal level of substance in cytosol def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cytosolic level of substance" EXACT [PomBase:mah] synonym: "normal level of substance in cytosol during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth is_a: FYPO:0001321 ! cellular structure phenotype during vegetative growth created_by: midori creation_date: 2012-09-27T13:19:00Z [Term] id: FYPO:0001607 name: decreased vacuolar aspartate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of aspartate in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar aspartate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar aspartic acid level" RELATED [PomBase:mah] synonym: "decreased vacuolar L-aspartate level" EXACT [PomBase:mah] synonym: "reduced level of aspartate in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar aspartate level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0001613 ! decreased cellular aspartate level created_by: midori creation_date: 2012-09-27T13:35:58Z [Term] id: FYPO:0001608 name: decreased vacuolar glutamate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of glutamate in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar glutamate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar glutamic acid level" RELATED [PomBase:mah] synonym: "decreased vacuolar L-glutamate level" EXACT [PomBase:mah] synonym: "reduced level of glutamate in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar glutamate level" EXACT [PomBase:mah] is_a: FYPO:0001563 ! decreased cellular glutamate level is_a: FYPO:0001602 ! decreased level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:37:52Z [Term] id: FYPO:0001609 name: decreased vacuolar ornithine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of ornithine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar L-ornithine level" EXACT [PomBase:mah] synonym: "decreased vacuolar ornithine level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of ornithine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar ornithine level" EXACT [PomBase:mah] is_a: FYPO:0001564 ! decreased cellular ornithine level is_a: FYPO:0001602 ! decreased level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:38:40Z [Term] id: FYPO:0001610 name: decreased vacuolar lysine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of lysine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar L-lysine level" EXACT [PomBase:mah] synonym: "decreased vacuolar lysine level during vegetative growth" EXACT [PomBase:mah] synonym: "reduced level of lysine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar lysine level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0001619 ! decreased cellular lysine level created_by: midori creation_date: 2012-09-27T13:40:52Z [Term] id: FYPO:0001611 name: decreased vacuolar histidine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of histidine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar histidine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar L-histidine level" EXACT [PomBase:mah] synonym: "reduced level of histidine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar histidine level" EXACT [PomBase:mah] is_a: FYPO:0001562 ! decreased cellular histidine level is_a: FYPO:0001602 ! decreased level of substance in vacuole created_by: midori creation_date: 2012-09-27T13:41:34Z [Term] id: FYPO:0001612 name: decreased vacuolar arginine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the vacuole is lower than normal." [PomBase:mah] synonym: "decreased level of arginine in vacuole" EXACT [PomBase:mah] synonym: "decreased vacuolar arginine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased vacuolar L-arginine level" EXACT [PomBase:mah] synonym: "reduced level of arginine in vacuole" EXACT [PomBase:mah] synonym: "reduced vacuolar arginine level" EXACT [PomBase:mah] is_a: FYPO:0001602 ! decreased level of substance in vacuole is_a: FYPO:0001621 ! decreased cellular arginine level created_by: midori creation_date: 2012-09-27T13:42:12Z [Term] id: FYPO:0001613 name: decreased cellular aspartate level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular aspartate level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular aspartic acid level" RELATED [PomBase:mah] synonym: "decreased cellular L-aspartate level" EXACT [PomBase:mah] synonym: "decreased cellular level aspartate level" EXACT [PomBase:mah] synonym: "decreased level of aspartate in cell" EXACT [PomBase:mah] synonym: "reduced cellular aspartate level" EXACT [PomBase:mah] synonym: "reduced level of aspartate in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T13:57:23Z [Term] id: FYPO:0001616 name: decreased cellular valine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-valine level" EXACT [PomBase:mah] synonym: "decreased cellular valine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of valine in cell" EXACT [PomBase:mah] synonym: "reduced cellular valine level" EXACT [PomBase:mah] synonym: "reduced level of valine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:00:08Z [Term] id: FYPO:0001617 name: decreased cellular isoleucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular isoleucine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-isoleucine level" EXACT [PomBase:mah] synonym: "decreased level of isoleucine in cell" EXACT [PomBase:mah] synonym: "reduced cellular isoleucine level" EXACT [PomBase:mah] synonym: "reduced level of isoleucine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:02:19Z [Term] id: FYPO:0001619 name: decreased cellular lysine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular L-lysine level" EXACT [PomBase:mah] synonym: "decreased cellular lysine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased level of lysine in cell" EXACT [PomBase:mah] synonym: "reduced cellular lysine level" EXACT [PomBase:mah] synonym: "reduced level of lysine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:03:22Z [Term] id: FYPO:0001621 name: decreased cellular arginine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the cell is lower than normal." [PomBase:mah] synonym: "decreased cellular arginine level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased cellular L-arginine level" EXACT [PomBase:mah] synonym: "decreased level of arginine in cell" EXACT [PomBase:mah] synonym: "reduced cellular arginine level" EXACT [PomBase:mah] synonym: "reduced level of arginine in cell" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:04:37Z [Term] id: FYPO:0001622 name: normal vacuolar threonine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of threonine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-threonine level" EXACT [PomBase:mah] synonym: "normal vacuolar threonine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole created_by: midori creation_date: 2012-09-27T14:07:43Z [Term] id: FYPO:0001623 name: normal vacuolar serine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of serine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-serine level" EXACT [PomBase:mah] synonym: "normal vacuolar serine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001635 ! normal cellular serine level created_by: midori creation_date: 2012-09-27T14:15:13Z [Term] id: FYPO:0001624 name: normal vacuolar asparagine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of asparagine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar asparagine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-asparagine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole created_by: midori creation_date: 2012-09-27T14:15:39Z [Term] id: FYPO:0001625 name: normal vacuolar glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of glutamine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-glutamine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001636 ! normal cellular glutamine level created_by: midori creation_date: 2012-09-27T14:16:08Z [Term] id: FYPO:0001626 name: normal vacuolar glycine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of glycine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar glycine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001637 ! normal cellular glycine level created_by: midori creation_date: 2012-09-27T14:16:32Z [Term] id: FYPO:0001627 name: normal vacuolar alanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of alanine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar alanine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-alanine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001638 ! normal cellular alanine level created_by: midori creation_date: 2012-09-27T14:17:07Z [Term] id: FYPO:0001628 name: normal vacuolar valine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of valine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-valine level" EXACT [PomBase:mah] synonym: "normal vacuolar valine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole created_by: midori creation_date: 2012-09-27T14:18:04Z [Term] id: FYPO:0001629 name: normal vacuolar methionine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of methionine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-methionine level" EXACT [PomBase:mah] synonym: "normal vacuolar methionine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001639 ! normal cellular methionine level created_by: midori creation_date: 2012-09-27T14:18:27Z [Term] id: FYPO:0001630 name: normal vacuolar isoleucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of isoleucine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar isoleucine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal vacuolar L-isoleucine level" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole created_by: midori creation_date: 2012-09-27T14:18:49Z [Term] id: FYPO:0001631 name: normal vacuolar leucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-leucine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of leucine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-leucine level" EXACT [PomBase:mah] synonym: "normal vacuolar leucine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001640 ! normal cellular leucine level created_by: midori creation_date: 2012-09-27T14:19:17Z [Term] id: FYPO:0001632 name: normal vacuolar tyrosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of tyrosine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-tyrosine level" EXACT [PomBase:mah] synonym: "normal vacuolar tyrosine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001641 ! normal cellular tyrosine level created_by: midori creation_date: 2012-09-27T14:20:13Z [Term] id: FYPO:0001633 name: normal vacuolar phenylalanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-phenylalanine measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of phenylalanine in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar L-phenylalanine level" EXACT [PomBase:mah] synonym: "normal vacuolar phenylalanine level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001642 ! normal cellular phenylalanine level created_by: midori creation_date: 2012-09-27T14:20:37Z [Term] id: FYPO:0001634 name: normal vacuolar tryptophan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of tryptophan measured in the vacuole is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal level of tryptophan in vacuole" EXACT [PomBase:mah] synonym: "normal vacuolar tryptophan level during vegetative growth" EXACT [PomBase:mah] is_a: FYPO:0001603 ! normal level of substance in vacuole is_a: FYPO:0001643 ! normal cellular tryptophan level created_by: midori creation_date: 2012-09-27T14:21:05Z [Term] id: FYPO:0001635 name: normal cellular serine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-serine level" EXACT [PomBase:mah] synonym: "normal cellular serine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of serine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:42:14Z [Term] id: FYPO:0001636 name: normal cellular glutamine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular glutamine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular L-glutamine level" EXACT [PomBase:mah] synonym: "normal level of glutamine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:43:22Z [Term] id: FYPO:0001637 name: normal cellular glycine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glycine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular glycine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular L-glycine level" EXACT [PomBase:mah] synonym: "normal level of glycine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:43:46Z [Term] id: FYPO:0001638 name: normal cellular alanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular alanine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal cellular L-alanine level" EXACT [PomBase:mah] synonym: "normal level of alanine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:44:07Z [Term] id: FYPO:0001639 name: normal cellular methionine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-methionine level" EXACT [PomBase:mah] synonym: "normal cellular methionine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of methionine in cell" EXACT [PomBase:mah] is_a: FYPO:0001544 ! normal cellular sulfur level created_by: midori creation_date: 2012-09-27T14:44:34Z [Term] id: FYPO:0001640 name: normal cellular leucine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-leucine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-leucine level" EXACT [PomBase:mah] synonym: "normal cellular leucine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of leucine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:44:59Z [Term] id: FYPO:0001641 name: normal cellular tyrosine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-tyrosine level" EXACT [PomBase:mah] synonym: "normal cellular tyrosine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of tyrosine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:45:39Z [Term] id: FYPO:0001642 name: normal cellular phenylalanine level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-phenylalanine measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular L-phenylalanine level" EXACT [PomBase:mah] synonym: "normal cellular phenylalanine level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of phenylalanine in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:46:14Z [Term] id: FYPO:0001643 name: normal cellular tryptophan level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of tryptophan measured in the cell is normal (i.e. indistinguishable from wild type)." [PomBase:mah] synonym: "normal cellular tryptophan level during vegetative growth" EXACT [PomBase:mah] synonym: "normal level of tryptophan in cell" EXACT [PomBase:mah] is_a: FYPO:0001316 ! normal level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:46:41Z [Term] id: FYPO:0001644 name: decreased cellular lithium level def: "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lithium ion measured in a cell is lower than normal." [PomBase:mah] synonym: "decreased cellular lithium ion level" EXACT [PomBase:mah] synonym: "decreased cellular lithium level during vegetative growth" EXACT [PomBase:mah] synonym: "decreased lithium accumulation" RELATED [PomBase:al] synonym: "reduced cellular lithium level" EXACT [PomBase:mah] is_a: FYPO:0001329 ! decreased level of substance in cell during vegetative growth created_by: midori creation_date: 2012-09-27T14:48:30Z [Term] id: FYPO:0001645 name: decreased protein binding def: "A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal." [PomBase:mah] comment: This term can be used for any protein-protein interaction that is affected by a mutation, whether or not the mutated gene product is one of the interacting proteins. We recommend noting which proteins were used in the assay when annotating to this term. synonym: "decreased protein-protein interaction" EXACT [PomBase:mah] synonym: "reduced protein binding" EXACT [PomBase:mah] is_a: FYPO:0000704 ! abnormal protein binding created_by: midori creation_date: 2012-09-27T14:50:07Z [Term] id: FYPO:0001646 name: abnormal glutamate import def: "A cellular process phenotype in which the import of glutamate into the cell is abnormal." [PomBase:mah] comment: This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. subset: qc_do_not_manually_annotate is_a: FYPO:0001057 ! abnormal amino acid import created_by: midori creation_date: 2012-09-27T15:50:49Z [Term] id: FYPO:0001647 name: abnormal glutamate import during nitrogen starvation def: "A cellular process phenotype in which the import of L-glutamate into the cell is abnormal when the cell is subject to nitrogen starvation." [PomBase:mah] synonym: "abnormal glutamate import into cell during nitrogen starvation" EXACT [PomBase:al] synonym: "abnormal glutamate uptake during nitrogen starvation" EXACT [GO:0051938] synonym: "abnormal L-glutamate import during nitrogen starvation" NARROW [PomBase:mah] is_a: FYPO:0001646 ! abnormal glutamate import is_a: FYPO:0001648 ! ab