# refs

id: PMID:24309281
data:
  {"abstract":"How do nuclear components, apart from chromosomes, partition equally to daughter nuclei during mitosis? In Schizosaccharomyces japonicus, the conserved LEM-domain nuclear envelope protein Man1 ensures the formation of identical daughter nuclei by coupling nuclear pore complexes to the segregating chromosomes. ","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Walters AD, Cohen-Fix O","authors_abbrev":"Walters AD et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Review or comment","citation":"Curr Biol 2013 Dec 02;23(23):R1045-7","cv_annotations":{},"doi":"10.1016/j.cub.2013.10.041","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2013","pubmed_entrez_date":"2013-12-07","pubmed_publication_date":"02 Dec 2013","terms_by_termid":{},"title":"Nuclear division: giving daughters their fair share.","uniquename":"PMID:24309281"}


id: PMID:23090706
data:
  {"abstract":"DNA damage response includes DNA repair, nucleotide metabolism and even a control of cell fates including differentiation, cell death pathway or some combination of these. The responses to DNA damage differ from species to species. Here we aim to delineate the checkpoint pathway in the dimorphic fission yeast Schizosaccharomyces japonicus, where DNA damage can trigger a differentiation pathway that is a switch from a bidirectional yeast growth mode to an apical hyphal growth mode, and the switching is regulated via a checkpoint kinase, Chk1. This Chk1-dependent switch to hyphal growth is activated with even low doses of agents that damage DNA; therefore, we reasoned that this switch may depend on other genes orthologous to the components of the classical Sz. pombe Chk1-dependent DNA checkpoint pathway. As an initial test of this hypothesis, we assessed the effects of mutations in Sz. japonicus orthologs of Sz. pombe checkpoint genes on this switch from bidirectional to hyphal growth. The same set of DNA checkpoint genes was confirmed in Sz. japonicus. We tested the effect of each DNA checkpoint mutants on hyphal differentiation by DNA damage. We found that the Sz. japonicus hyphal differentiation pathway was dependent on Sz. japonicus orthologs of Sz. pombe checkpoint genes-(SP)rad3, (SP)rad26, (SP)rad9, (SP)rad1, (SP)rad24, (SP)rad25, (SP)crb2, and (SP)chk1-that function in the DNA damage checkpoint pathway, but was not dependent on orthologs of two Sz. pombe genes-(SP)cds1 or (SP)mrc1-that function in the DNA replication checkpoint pathway. These findings indicated that although the role of each component of the DNA damage checkpoint and DNA replication checkpoint is mostly same between the two fission yeasts, the DNA damage checkpoint was the only pathway that governed DNA damage-dependent hyphal growth. We also examined whether DNA damage checkpoint signaling engaged in functional crosstalk with other hyphal differentiation pathways because hyphal differentiation can also be triggered by nutritional stress. Here, we discovered genetic interactions that indicated that the cAMP pathway engaged in crosstalk with Chk1-dependent signaling.","alleles_by_uniquename":{"SJAG_00364:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00364","name":"rad3delta","uniquename":"SJAG_00364:allele-1"},"SJAG_00429:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00429","name":"rad26delta","uniquename":"SJAG_00429:allele-1"},"SJAG_01205:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01205","name":"crb2delta","uniquename":"SJAG_01205:allele-1"},"SJAG_01605:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01605","name":"rad9delta","uniquename":"SJAG_01605:allele-1"},"SJAG_01680:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01680","name":"chk1delta","uniquename":"SJAG_01680:allele-1"},"SJAG_01680:allele-2":{"allele_type":"amino_acid_mutation","description":"P470L","gene_uniquename":"SJAG_01680","name":"chk1-P470L","synonyms":[{"name":"chk1- hyperactive (chk1-hyp)","reference":"PMID:23090706","type":"exact"},{"name":"chk1-hyperactive (chk1-hyp)","reference":"PMID:20368354","type":"exact"}],"uniquename":"SJAG_01680:allele-2"},"SJAG_02266:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02266","name":"rad24delta","uniquename":"SJAG_02266:allele-1"},"SJAG_02576:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02576","name":"rad25delta","uniquename":"SJAG_02576:allele-1"},"SJAG_02771:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02771","name":"rad1delta","uniquename":"SJAG_02771:allele-1"},"SJAG_03720:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03720","name":"tel1delta","uniquename":"SJAG_03720:allele-1"},"SJAG_04287:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04287","name":"cds1delta","uniquename":"SJAG_04287:allele-1"},"SJAG_04671:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04671","name":"mrc1delta","uniquename":"SJAG_04671:allele-1"}},"annotation_curators":[{"annotation_count":28,"community_curator":true,"file_name":null,"file_type":null,"name":"Sho Okamoto","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2022-11-21","authors":"Furuya K, Niki H","authors_abbrev":"Furuya K et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2022-11-21 17:21:20","canto_curator_name":"Sho Okamoto","canto_curator_role":"community","canto_first_approved_date":"2022-11-21 17:21:20","canto_session_key":"5f68f94ee65a99b7","canto_session_submitted_date":"2022-11-21 17:21:13","canto_triage_status":"Curatable","citation":"Curr Genet 2012 Dec;58(5-6):291-303","cv_annotations":{"multi_locus_phenotype":[{"annotations":[114414],"is_not":false,"summary":null,"term":"FYPO:0007790"},{"annotations":[114420],"is_not":false,"summary":null,"term":"FYPO:0000085"},{"annotations":[114417],"is_not":false,"summary":null,"term":"FYPO:0000088"}],"single_locus_phenotype":[{"annotations":[114405,114406,114407,114408,114409,114410,114412,114413],"is_not":false,"summary":null,"term":"FYPO:0007782"},{"annotations":[114431],"is_not":false,"summary":null,"term":"FYPO:0007774"},{"annotations":[114430],"is_not":false,"summary":null,"term":"FYPO:0001690"},{"annotations":[114404,114411],"is_not":false,"summary":null,"term":"FYPO:0007790"},{"annotations":[114429],"is_not":false,"summary":null,"term":"FYPO:0004693"},{"annotations":[114418,114419,114424,114425,114426],"is_not":false,"summary":null,"term":"FYPO:0000085"},{"annotations":[114415,114416,114421,114422,114423],"is_not":false,"summary":null,"term":"FYPO:0000088"},{"annotations":[114427,114428],"is_not":false,"summary":null,"term":"FYPO:0001234"}]},"doi":"10.1007/s00294-012-0384-4","gene_count":11,"genes_by_uniquename":{"SJAG_00364":null,"SJAG_00429":null,"SJAG_01205":null,"SJAG_01605":null,"SJAG_01680":null,"SJAG_02266":null,"SJAG_02576":null,"SJAG_02771":null,"SJAG_03720":null,"SJAG_04287":null,"SJAG_04671":null},"genotypes_by_uniquename":{"cds1delta":{"display_name":"cds1delta","display_uniquename":"cds1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04287:allele-1","expression":"Null"}]}]},"chk1-P470L-P470L-amino_acid_mutation-expression-not_assayed_or_wild_type__rad24delta":{"display_name":"chk1-P470L(aa) rad24delta","display_uniquename":"chk1-P470L-P470L-amino_acid_mutation-expression-not_assayed_or_wild_type__rad24delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01680:allele-2","expression":"Not assayed or wild type"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_02266:allele-1","expression":"Null"}]}]},"chk1delta":{"display_name":"chk1delta","display_uniquename":"chk1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01680:allele-1","expression":"Null"}]}]},"chk1delta__crb2delta":{"display_name":"chk1delta crb2delta","display_uniquename":"chk1delta__crb2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01680:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_01205:allele-1","expression":"Null"}]}]},"crb2delta":{"display_name":"crb2delta","display_uniquename":"crb2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01205:allele-1","expression":"Null"}]}]},"mrc1delta":{"display_name":"mrc1delta","display_uniquename":"mrc1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04671:allele-1","expression":"Null"}]}]},"rad1delta":{"display_name":"rad1delta","display_uniquename":"rad1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02771:allele-1","expression":"Null"}]}]},"rad24delta":{"display_name":"rad24delta","display_uniquename":"rad24delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02266:allele-1","expression":"Null"}]}]},"rad25delta":{"display_name":"rad25delta","display_uniquename":"rad25delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02576:allele-1","expression":"Null"}]}]},"rad26delta":{"display_name":"rad26delta","display_uniquename":"rad26delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00429:allele-1","expression":"Null"}]}]},"rad3delta":{"display_name":"rad3delta","display_uniquename":"rad3delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00364:allele-1","expression":"Null"}]}]},"rad9delta":{"display_name":"rad9delta","display_uniquename":"rad9delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01605:allele-1","expression":"Null"}]}]},"tel1delta":{"display_name":"tel1delta","display_uniquename":"tel1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03720:allele-1","expression":"Null"}]}]}},"ltp_gene_count":11,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2012","pubmed_entrez_date":"2012-10-24","pubmed_publication_date":"Dec 2012","references_by_uniquename":{"PMID:20368354":null,"PMID:23090706":null},"terms_by_termid":{"FYECO:0000005":null,"FYECO:0000137":null,"FYECO:0000314":null,"FYPO:0000085":null,"FYPO:0000088":null,"FYPO:0001234":null,"FYPO:0001690":null,"FYPO:0004693":null,"FYPO:0007774":null,"FYPO:0007782":null,"FYPO:0007790":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null,"FYPO_EXT:0000003":null},"title":"Hyphal differentiation induced via a DNA damage checkpoint-dependent pathway engaged in crosstalk with nutrient stress signaling in Schizosaccharomyces japonicus.","uniquename":"PMID:23090706"}


id: PMID:11921097
data:
  {"abstract":"The dimorphic fission yeast Schizosaccharomyces japonicus has proved to be an excellent experimental model for the investigation of the eukaryotic cell. Here we show that it has a haplontic life cycle, in which the diploid phase is confined to the zygote. To make it amenable to genetic and molecular analysis, we generated genetic markers and cloned a genomic sequence which acts as ars when integrated into a plasmid. Diploids suitable for testing complementation and recombination between markers can be formed by protoplast fusion. The complementation tests and the recombination frequencies determined in octads of spores identified 28 non-allelic groups (genes) of mutations of the auxotrophic and mycelium-negative mutants. Two groups of linked markers were also identified. The cloned fragment, which expresses ars activity, encodes a putative amino acid sequence highly similar to a conserved domain of proteins Cut1 (Schizosaccharomyces pombe), BimB (Aspergillus nidulans) and Esp1 (Saccharomyces cerevisiae).","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Bozsik A, Szilagyi Z, Benko Z, Sipiczki M","authors_abbrev":"Bozsik A et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Method or reagent","citation":"Yeast 2002 Apr;19(6):485-98","cv_annotations":{},"gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2002","pubmed_entrez_date":"2002-03-29","pubmed_publication_date":"Apr 2002","terms_by_termid":{},"title":"Marker construction and cloning of a cut1-like sequence with ARS activity in the fission yeast Schizosaccharomyces japonicus.","uniquename":"PMID:11921097"}


id: PMID:26343758
data:
  {"abstract":"CENP-A is a centromere-specific histone H3 variant that is required for kinetochore assembly and accurate chromosome segregation. For it to function properly, CENP-A must be specifically localized to centromeres. In fission yeast, Scm3sp and the Mis18 complex, composed of Mis16, Eic1, and Mis18, function as a CENP-A(Cnp1)-specific chaperone and a recruiting factor, respectively, and together ensure accurate delivery of CENP-A(Cnp1) to centromeres. Although how Scm3sp specifically recognizes CENP-A(Cnp1) has been revealed recently, the recruiting mechanism of CENP-A(Cnp1) via the Mis18 complex remains unknown. In this study, we have determined crystal structures of Schizosaccharomyces japonicus Mis16 alone and in complex with the helix 1 of histone H4 (H4α1). Crystal structures followed by mutant analysis and affinity pull-downs have revealed that Mis16 recognizes both H4α1 and Scm3sp independently within the CENP-A(Cnp1)/H4:Scm3sp complex. This observation suggests that Mis16 gains CENP-A(Cnp1) specificity by recognizing both Scm3sp and histone H4. Our studies provide insights into the molecular mechanisms underlying specific recruitment of CENP-A(Cnp1)/H4:Scm3sp into centromeres. ","alleles_by_uniquename":{},"annotation_curators":[{"annotation_count":4,"community_curator":false,"file_name":null,"file_type":null,"name":"Val Wood","orcid":"0000-0001-6330-7526"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-05-13","authors":"An S, Kim H, Cho US","authors_abbrev":"An S et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2021-05-13 14:11:41","canto_curator_name":"Val Wood","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-05-13 14:11:41","canto_session_key":"fb189c5ef542852c","canto_session_submitted_date":"2021-05-12 16:00:22","canto_triage_status":"Curatable","citation":"J Mol Biol 2015 Oct 09;427(20):3230-3240","cv_annotations":{"molecular_function":[{"annotations":[114364,114365,114366,114367],"is_not":false,"summary":null,"term":"GO:0042393"}]},"doi":"10.1016/j.jmb.2015.08.022","gene_count":4,"genes_by_uniquename":{"SJAG_00303":null,"SJAG_02513":null,"SJAG_03542":null,"SJAG_03867":null},"genotypes_by_uniquename":{},"ltp_gene_count":3,"ortholog_annotations":[],"paralog_annotations":[],"pdb_entries":[{"entry_authors":"An S,Kim H,Cho U-S","entry_authors_abbrev":"An S et al.","experimental_method":"X-ray","gene_chains":[{"chain":"A","gene_uniquename":"SJAG_03867","position":"1-427"}],"pdb_id":"4xyh","reference_uniquename":"PMID:26343758","resolution":"2.3","title":"Wild-type full length Mis16 in Schizosaccharomyces japonicus"},{"entry_authors":"An S,Kim H,Cho U-S","entry_authors_abbrev":"An S et al.","experimental_method":"X-ray","gene_chains":[{"chain":"B","gene_uniquename":"SJAG_03542","position":"1-103"},{"chain":"A","gene_uniquename":"SJAG_03867","position":"1-427"}],"pdb_id":"4xyi","reference_uniquename":"PMID:26343758","resolution":"3.0","title":"Mis16 with H4 peptide"}],"physical_interactions":[],"publication_year":"2015","pubmed_entrez_date":"2015-09-08","pubmed_publication_date":"09 Oct 2015","terms_by_termid":{"GO:0042393":null},"title":"Mis16 Independently Recognizes Histone H4 and the CENP-ACnp1-Specific Chaperone Scm3sp.","uniquename":"PMID:26343758"}


id: PMID:34427722
data:
  {"abstract":"Fungal pathogens, from phytopathogenic fungus to human pathogens, are able to alternate between the yeast-like form and filamentous forms. This morphological transition (dimorphism) is in close connection with their pathogenic lifestyles and with their responses to changing environmental conditions. The mechanisms governing these morphogenetic conversions are still not fully understood. Therefore, we studied the filamentous growth of the less-known, non-pathogenic dimorphic fission yeast, S. japonicus, which belongs to an ancient and early evolved branch of the Ascomycota. Its RNA sequencing revealed that several hundred genes were up- or down-regulated in the hyphae compared to the yeast-phase cells. These genes belonged to different GO categories, confirming that mycelial growth is a rather complex process. The genes of transport- and metabolic processes appeared especially in high numbers among them. High expression of genes involved in glycolysis and ethanol production was found in the hyphae, while other results pointed to the regulatory role of the protein kinase A (PKA) pathway. The homologues of 49 S. japonicus filament-associated genes were found by sequence alignments also in seven distantly related dimorphic and filamentous species. The comparative genomic analyses between S. japonicus and the closely related but non-dimorphic S. pombe shed some light on the differences in their genomes. All these data can contribute to a better understanding of hyphal growth and those genomic rearrangements that underlie it.","alleles_by_uniquename":{},"annotation_curators":[{"annotation_count":2,"community_curator":true,"file_name":null,"file_type":null,"name":"Ida Miklos","orcid":"0000-0002-7074-4019"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-10-06","authors":"Papp LA, Ács-Szabó L, Batta G, Miklós I","authors_abbrev":"Papp LA et al.","canto_added_date":"2021-09-29 13:11:40","canto_annotation_status":"APPROVED","canto_approved_date":"2021-10-06 13:34:09","canto_curator_name":"Ida Miklos","canto_curator_role":"community","canto_first_approved_date":"2021-10-06 13:34:09","canto_session_key":"acb5c82405799ef1","canto_session_submitted_date":"2021-09-29 13:38:18","canto_triage_status":"Curatable","citation":"Curr Genet 2021 Dec;67(6):953-968","cv_annotations":{"biological_process":[{"annotations":[114505,114506],"is_not":false,"summary":null,"term":"GO:0030448"}]},"doi":"10.1007/s00294-021-01206-y","gene_count":2,"genes_by_uniquename":{"SJAG_00124":null,"SJAG_04312":null},"genotypes_by_uniquename":{},"ltp_gene_count":2,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2021","pubmed_entrez_date":"2021-08-24","pubmed_publication_date":"Dec 2021","terms_by_termid":{"GO:0030448":null},"title":"Molecular and comparative genomic analyses reveal evolutionarily conserved and unique features of the Schizosaccharomyces japonicus mycelial growth and the underlying genomic changes.","uniquename":"PMID:34427722"}


id: PMID:8590481
data:
  {"abstract":"Fission yeasts form a small but heterogeneous group of ascomycetes and it is still unclear whether they should be subdivided into three genera (Schizosaccharomyces, Octosporomyces, Hasegawaea) or remain a single genus (Schizosaccharomyces). In order to decide whether a new genus Hasegawaea should be established for the species Schizosaccharomyces japonicus and Schizosaccharomyces versatilis, we have characterized the entire rDNA cluster in Schizosaccharomyces japonicus var. versatilis and compared it with the homologous region from Schizosaccharomyces pombe and with complete rRNA gene sequences from other yeast genera. From a phage genomic library a recombinant lambda phage containing the entire rDNA repeat unit was isolated. In this paper we report the primary sequence of the 18s, 5.8s and 25s rRNA coding regions. The S. japonicus var. versatilis rRNA genes are 1823 (18s), 158 (5.8s) and 3422 (25s) nucleotides long. The two sequences of the larger rRNA genes exhibit 95.7% (18s) and 93% (25s) similarity with the homologous genes from S. pombe. The differences between the rRNA genes of S. japonicus and S. pombe, however, are much smaller than the intrageneric differences within the rDNA sequences of other yeast genera. Therefore, subdivision of fission yeasts into the genera Schizosaccharomyces and Hasegawaea does not to seem to be justified.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Naehring J, Kiefer S, Wolf K","authors_abbrev":"Naehring J et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Sequence feature or region","citation":"Curr Genet 1995 Sep;28(4):353-9","cv_annotations":{},"gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"1995","pubmed_entrez_date":"1995-09-01","pubmed_publication_date":"Sep 1995","terms_by_termid":{},"title":"Nucleotide sequence of the Schizosaccharomyces japonicus var. versatilis ribosomal RNA gene cluster and its phylogenetic implications.","uniquename":"PMID:8590481"}


id: PMID:33837814
data:
  {"abstract":"The capability of RNA isolation with good efficiency and high quality is essential for a downstream application such as RNA sequencing. It requires successful cell culturing and an effective RNA isolation method. Although effective methods are available, production of the homogenous mycelia and extraction of good-quality mycelial RNA from true invasive hyphae, which penetrated into the agar plates, are difficult. To overcome these problems, the aim of this study was to develop technical modifications which allow production of homogenous mycelial biomass without extra stimuli agents and improve quality of the RNA extracted from the fungal hyphae. Our alternative culture medium was suitable for production both yeast-phase cells and hyphae of the Schizosaccharomyces japonicus and other dimorphic species, such as the Candida albicans, Saccharomyces cerevisiae, and Jaminaea angkorensis. To improve quality of the mycelial RNA, we developed an isolation procedure of the hyphal tip, which eliminated the unnecessary vacuoles-containing parts of the hyphae. To increase RNA quantity, we used glass beads in the RNA extraction protocol to achieve stronger breaking of the mycelial walls. All these modifications can also be useful for researchers working with other dimorphic fungi and can contribute to the higher comparability of the transcriptional data coming from yeast-phase cells and hyphae or even from different species.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Papp LA, Ács-Szabó L, Póliska S, Miklós I","authors_abbrev":"Papp LA et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Method or reagent","citation":"Curr Genet 2021 Oct;67(5):823-830","cv_annotations":{},"doi":"10.1007/s00294-021-01181-4","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2021","pubmed_entrez_date":"2021-04-10","pubmed_publication_date":"Oct 2021","terms_by_termid":{},"title":"A modified culture medium and hyphae isolation method can increase quality of the RNA extracted from mycelia of a dimorphic fungal species.","uniquename":"PMID:33837814"}


id: PMID:31732056
data:
  {"abstract":"Vitis davidii Föex is widely planted in South China as a potential wine making grape. In this study, yeast communities during the spontaneous fermentations of two varieties of Vitis davidii Föex in Guizhou, China were investigated. Hanseniaspora uvarum, Pichia terricola, Saccharomyces cerevisiae/S. mikatae, and Schizosaccharomyces japonicus were the four main yeast species detected by culture-dependent and high-throughput sequencing approaches. However, the composition of minor yeast species was quite different as revealed by the two approaches. Ten yeast species including Debaryomyces hansenii, Rhodotorula mucilaginosa, Sporidiobolus paraoseus, Starmerella bacillaris, Zygoascus meyerae, etc. were detected by culture-dependent approaches, whereas the other five species were found by high-throughput sequencing analysis. S. japonicus was widely found during spontaneous fermentations and its concentrations were mostly higher than that of S. cerevisiae. The difference in grape varieties and fermentation conditions contributed to yeast diversity. The results of this study provide basic information on indigenous yeast diversity from Vitis davidii Föex in Guizhou, which would help to exploit the potential of non-Saccharomyces yeast species with good oenological attributes.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Wang C, Wu C, Qiu S","authors_abbrev":"Wang C et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Biotech","citation":"Food Res Int 2019 12;126:108582","cv_annotations":{},"doi":"10.1016/j.foodres.2019.108582","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2019","pubmed_entrez_date":"2019-11-17","pubmed_publication_date":"12 2019","terms_by_termid":{},"title":"Yeast diversity investigation of Vitis davidii Föex during spontaneous fermentations using culture-dependent and high-throughput sequencing approaches.","uniquename":"PMID:31732056"}


id: GO_REF:0000108
data:
  {"alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"canto_curator_role":"JaponicusDB","cv_annotations":{"biological_process":[{"annotations":[65772],"is_not":false,"summary":null,"term":"GO:0071266"},{"annotations":[61539],"is_not":false,"summary":null,"term":"GO:0042886"},{"annotations":[56795,57207,57763,58994,61663,63533,64224,64246,66976],"is_not":false,"summary":null,"term":"GO:0106074"},{"annotations":[69055],"is_not":false,"summary":null,"term":"GO:0140331"},{"annotations":[66551],"is_not":false,"summary":null,"term":"GO:0009785"},{"annotations":[64094],"is_not":false,"summary":null,"term":"GO:0070574"},{"annotations":[60899,64910],"is_not":false,"summary":null,"term":"GO:0034219"},{"annotations":[58323,69340,69627],"is_not":false,"summary":null,"term":"GO:1905039"},{"annotations":[57179],"is_not":false,"summary":null,"term":"GO:0098869"},{"annotations":[57783,58047,58351,59285,61074,62114,62170,62219,63928,65596,65682,66137,66455,66614,67163,68541,69015,69557],"is_not":false,"summary":null,"term":"GO:0006338"},{"annotations":[68154],"is_not":false,"summary":null,"term":"GO:0009224"},{"annotations":[62824,63215],"is_not":false,"summary":null,"term":"GO:0071897"},{"annotations":[62861,63446,65964,69423],"is_not":false,"summary":null,"term":"GO:0022900"},{"annotations":[64668,65910],"is_not":false,"summary":null,"term":"GO:0006897"},{"annotations":[61740],"is_not":false,"summary":null,"term":"GO:0140479"},{"annotations":[63326],"is_not":false,"summary":null,"term":"GO:0006868"},{"annotations":[59247],"is_not":false,"summary":null,"term":"GO:0006177"},{"annotations":[63869],"is_not":false,"summary":null,"term":"GO:1903790"},{"annotations":[64602],"is_not":false,"summary":null,"term":"GO:0051170"},{"annotations":[57145],"is_not":false,"summary":null,"term":"GO:0120009"},{"annotations":[63324],"is_not":false,"summary":null,"term":"GO:1903826"},{"annotations":[61346],"is_not":false,"summary":null,"term":"GO:0097052"},{"annotations":[65885],"is_not":false,"summary":null,"term":"GO:0015825"},{"annotations":[59174,60249,60878],"is_not":false,"summary":null,"term":"GO:0019249"},{"annotations":[57274,61165,69826],"is_not":false,"summary":null,"term":"GO:0098734"},{"annotations":[56727],"is_not":false,"summary":null,"term":"GO:1903830"},{"annotations":[64652],"is_not":false,"summary":null,"term":"GO:1901553"},{"annotations":[60308,69211],"is_not":false,"summary":null,"term":"GO:0061025"},{"annotations":[59172,60876],"is_not":false,"summary":null,"term":"GO:0061727"},{"annotations":[61802,65938],"is_not":false,"summary":null,"term":"GO:0098656"},{"annotations":[57997],"is_not":false,"summary":null,"term":"GO:0098655"},{"annotations":[65886],"is_not":false,"summary":null,"term":"GO:0034220"},{"annotations":[64062],"is_not":false,"summary":null,"term":"GO:0035672"},{"annotations":[59370],"is_not":false,"summary":null,"term":"GO:0035435"},{"annotations":[61736,63359],"is_not":false,"summary":null,"term":"GO:0036092"},{"annotations":[57143],"is_not":false,"summary":null,"term":"GO:0043410"},{"annotations":[61357,65433,67334,67375,68500,69026],"is_not":false,"summary":null,"term":"GO:1901800"},{"annotations":[61886,62812,63127,65464,66431],"is_not":false,"summary":null,"term":"GO:0045944"},{"annotations":[57240,61250,67515],"is_not":false,"summary":null,"term":"GO:0071805"},{"annotations":[58872],"is_not":false,"summary":null,"term":"GO:0006457"},{"annotations":[56897,60963,66867],"is_not":false,"summary":null,"term":"GO:0071806"},{"annotations":[67645],"is_not":false,"summary":null,"term":"GO:0015986"},{"annotations":[57245,59190,59518,59658,60550,60898,61236,61678,61851,62041,63056,63567,63996,64096,64909,68148,68907],"is_not":false,"summary":null,"term":"GO:1902600"},{"annotations":[57255,66486,68825],"is_not":false,"summary":null,"term":"GO:0006357"},{"annotations":[57888],"is_not":false,"summary":null,"term":"GO:0019430"},{"annotations":[59764],"is_not":false,"summary":null,"term":"GO:0106005"},{"annotations":[65046,67460],"is_not":false,"summary":null,"term":"GO:0051123"},{"annotations":[57899,58340,59362,60360,62486,63386,64148,64287,68291],"is_not":false,"summary":null,"term":"GO:0001172"},{"annotations":[64434],"is_not":false,"summary":null,"term":"GO:0031167"},{"annotations":[61237,67516],"is_not":false,"summary":null,"term":"GO:0035725"},{"annotations":[57569],"is_not":false,"summary":null,"term":"GO:1903711"},{"annotations":[61746],"is_not":false,"summary":null,"term":"GO:1902981"},{"annotations":[61890],"is_not":false,"summary":null,"term":"GO:0006415"},{"annotations":[57019],"is_not":false,"summary":null,"term":"GO:0055085"},{"annotations":[61023],"is_not":false,"summary":null,"term":"GO:0099116"},{"annotations":[63325],"is_not":false,"summary":null,"term":"GO:0015828"}],"cellular_component":[{"annotations":[62089],"is_not":false,"summary":null,"term":"GO:0005938"},{"annotations":[58447,58721,59528,59804,59957,61446,62678,64194,65697,66207,66569,69497,69774],"is_not":false,"summary":null,"term":"GO:0140445"},{"annotations":[56777,58809,58982,60507,61450,61511,61579,62811,64006,64722,65366,66448,66690,67311,67879,69231,69238],"is_not":false,"summary":null,"term":"GO:0005829"},{"annotations":[60303],"is_not":false,"summary":null,"term":"GO:0005783"},{"annotations":[58572,66548],"is_not":false,"summary":null,"term":"GO:0000139"},{"annotations":[58702],"is_not":false,"summary":null,"term":"GO:0005739"},{"annotations":[60015,65329,69916],"is_not":false,"summary":null,"term":"GO:0005773"}]},"gene_count":165,"genes_by_uniquename":{"SJAG_00057":null,"SJAG_00063":null,"SJAG_00111":null,"SJAG_00119":null,"SJAG_00175":null,"SJAG_00211":null,"SJAG_00232":null,"SJAG_00233":null,"SJAG_00287":null,"SJAG_00293":null,"SJAG_00353":null,"SJAG_00399":null,"SJAG_00443":null,"SJAG_00455":null,"SJAG_00458":null,"SJAG_00475":null,"SJAG_00500":null,"SJAG_00576":null,"SJAG_00596":null,"SJAG_00601":null,"SJAG_00650":null,"SJAG_00669":null,"SJAG_00671":null,"SJAG_00676":null,"SJAG_00678":null,"SJAG_00687":null,"SJAG_00712":null,"SJAG_00756":null,"SJAG_00760":null,"SJAG_00766":null,"SJAG_00774":null,"SJAG_00785":null,"SJAG_00832":null,"SJAG_00884":null,"SJAG_00899":null,"SJAG_00906":null,"SJAG_00943":null,"SJAG_00964":null,"SJAG_00976":null,"SJAG_00980":null,"SJAG_01007":null,"SJAG_01017":null,"SJAG_01027":null,"SJAG_01077":null,"SJAG_01082":null,"SJAG_01131":null,"SJAG_01146":null,"SJAG_01190":null,"SJAG_01248":null,"SJAG_01259":null,"SJAG_01309":null,"SJAG_01313":null,"SJAG_01355":null,"SJAG_01358":null,"SJAG_01435":null,"SJAG_01436":null,"SJAG_01471":null,"SJAG_01488":null,"SJAG_01489":null,"SJAG_01516":null,"SJAG_01540":null,"SJAG_01544":null,"SJAG_01583":null,"SJAG_01640":null,"SJAG_01707":null,"SJAG_01797":null,"SJAG_01809":null,"SJAG_01837":null,"SJAG_01916":null,"SJAG_01941":null,"SJAG_02015":null,"SJAG_02056":null,"SJAG_02070":null,"SJAG_02101":null,"SJAG_02106":null,"SJAG_02119":null,"SJAG_02120":null,"SJAG_02125":null,"SJAG_02177":null,"SJAG_02193":null,"SJAG_02204":null,"SJAG_02252":null,"SJAG_02268":null,"SJAG_02282":null,"SJAG_02330":null,"SJAG_02345":null,"SJAG_02428":null,"SJAG_02463":null,"SJAG_02504":null,"SJAG_02602":null,"SJAG_02646":null,"SJAG_02658":null,"SJAG_02691":null,"SJAG_02704":null,"SJAG_02768":null,"SJAG_02779":null,"SJAG_02780":null,"SJAG_02811":null,"SJAG_02860":null,"SJAG_02872":null,"SJAG_02912":null,"SJAG_02958":null,"SJAG_02972":null,"SJAG_02988":null,"SJAG_03166":null,"SJAG_03298":null,"SJAG_03315":null,"SJAG_03332":null,"SJAG_03356":null,"SJAG_03385":null,"SJAG_03386":null,"SJAG_03400":null,"SJAG_03401":null,"SJAG_03487":null,"SJAG_03490":null,"SJAG_03537":null,"SJAG_03545":null,"SJAG_03546":null,"SJAG_03613":null,"SJAG_03624":null,"SJAG_03625":null,"SJAG_03644":null,"SJAG_03708":null,"SJAG_03820":null,"SJAG_03879":null,"SJAG_03900":null,"SJAG_03943":null,"SJAG_03963":null,"SJAG_04023":null,"SJAG_04028":null,"SJAG_04030":null,"SJAG_04034":null,"SJAG_04068":null,"SJAG_04097":null,"SJAG_04112":null,"SJAG_04114":null,"SJAG_04147":null,"SJAG_04167":null,"SJAG_04190":null,"SJAG_04205":null,"SJAG_04219":null,"SJAG_04233":null,"SJAG_04265":null,"SJAG_04270":null,"SJAG_04285":null,"SJAG_04338":null,"SJAG_04374":null,"SJAG_04391":null,"SJAG_04400":null,"SJAG_04402":null,"SJAG_04404":null,"SJAG_04477":null,"SJAG_04545":null,"SJAG_04565":null,"SJAG_04588":null,"SJAG_04698":null,"SJAG_04712":null,"SJAG_04738":null,"SJAG_04788":null,"SJAG_04894":null,"SJAG_04902":null,"SJAG_04988":null,"SJAG_05234":null,"SJAG_05239":null,"SJAG_05325":null},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"terms_by_termid":{"GO:0000139":null,"GO:0001172":null,"GO:0005739":null,"GO:0005773":null,"GO:0005783":null,"GO:0005829":null,"GO:0005938":null,"GO:0006177":null,"GO:0006338":null,"GO:0006357":null,"GO:0006415":null,"GO:0006457":null,"GO:0006868":null,"GO:0006897":null,"GO:0009224":null,"GO:0009785":null,"GO:0015825":null,"GO:0015828":null,"GO:0015986":null,"GO:0019249":null,"GO:0019430":null,"GO:0022900":null,"GO:0031167":null,"GO:0034219":null,"GO:0034220":null,"GO:0035435":null,"GO:0035672":null,"GO:0035725":null,"GO:0036092":null,"GO:0042886":null,"GO:0043410":null,"GO:0045944":null,"GO:0051123":null,"GO:0051170":null,"GO:0055085":null,"GO:0061025":null,"GO:0061727":null,"GO:0070574":null,"GO:0071266":null,"GO:0071805":null,"GO:0071806":null,"GO:0071897":null,"GO:0097052":null,"GO:0098655":null,"GO:0098656":null,"GO:0098734":null,"GO:0098869":null,"GO:0099116":null,"GO:0106005":null,"GO:0106074":null,"GO:0120009":null,"GO:0140331":null,"GO:0140445":null,"GO:0140479":null,"GO:1901553":null,"GO:1901800":null,"GO:1902600":null,"GO:1902981":null,"GO:1903711":null,"GO:1903790":null,"GO:1903826":null,"GO:1903830":null,"GO:1905039":null},"uniquename":"GO_REF:0000108"}


id: PMID:1934083
data:
  {"abstract":"By rhodamine-phalloidin fluorescence, distinct continuous F-actin rings were visualized in 18-20% of the protoplasts of Schizosaccharomyces pombe and S. japonicus var. versatilis, in addition to randomly distributed F-actin dots. Whereas the reversion of ring-lacking protoplasts coincided with the polarization of the dotted F-actin pattern, the ring-containing protoplasts became furrowed as the F-actin rings constricted. The furrowing was more conspicuous in S. japonicus var. versatilis than in S. pombe protoplasts and it was blocked when the reversion was inhibited by Novozyme 234 indicating that the cell wall formation is essential for the F-actin ring constriction.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Jochová J, Rupes I, Streiblová E","authors_abbrev":"Jochová J et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Cell composition or WT feature","citation":"Cell Biol Int Rep 1991 Jul;15(7):607-10","cv_annotations":{},"gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"1991","pubmed_entrez_date":"1991-07-01","pubmed_publication_date":"Jul 1991","terms_by_termid":{},"title":"F-actin contractile rings in protoplasts of the yeast Schizosaccharomyces.","uniquename":"PMID:1934083"}


id: PMID:7214237
data:
  {"abstract":"Hybridization studies based on the prototrophic selection technique, involving the use of auxotrophic mutants of strains of five accepted species of the genus Schizosaccharomyces, are reported. Intrastrain recombinants were recovered in five out of six tested parental pairs. Interstrain recombinants were recovered from crosses involving strains of S. japonicus and strains of S. pombe. No recombinants were recovered in 62 interspecific crosses involving all possible combinations of the six representatives of the genus.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Johannsen E","authors_abbrev":"Johannsen E","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Cell composition or WT feature","citation":"Can J Microbiol 1981 Feb;27(2):184-91","cv_annotations":{},"gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"1981","pubmed_entrez_date":"1981-02-01","pubmed_publication_date":"Feb 1981","terms_by_termid":{},"title":"Hybridization studies within the genus Schizosaccharomyces Lindner.","uniquename":"PMID:7214237"}


id: PMID:34251689
data:
  {"abstract":"The polymerase chain reaction (PCR)-based gene targeting method, which can delete a specific gene or introduce tags, has been widely utilized to study gene function in fission yeast. One of the critical steps in this method is to design primers for amplifying DNA fragments of deletion or tagging modules and for checking the integration of those DNA fragments at designated loci. Although the primer design tool Pombe PCR Primer Program (PPPP) is available for Schizosaccharomyces pombe, there is no such publicly available application for the other three fission yeast species, S. cryophilus, S. japonicus, and S. octosporus. Likewise, no application enabling DNA/protein sequence retrieval for these three fission yeast species is available either. Therefore, access to such functionality would substantially assist in retrieval of gene sequences of interest and primer design in these fission yeast species. In this report, we describe two applications for fission yeast study: Yesprit and Yeaseq. Yesprit is a primer design tool for strain construction using the PCR-based method, and Yeaseq is a sequence viewer that can acquire the DNA/protein sequences of specific genes. Both tools can be run on the Windows, macOS, and Linux platforms. We believe that the Yesprit and Yeaseq will facilitate research using the four fission yeast species.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Wang X, Xu R, Wang Y, Liu Z, Lou R, Sugiyama T","authors_abbrev":"Wang X et al.","canto_added_date":"2023-05-04 00:40:04","canto_curator_role":"JaponicusDB","canto_triage_status":"Method or reagent","citation":"Yeast 2021 Nov;38(11):583-591","cv_annotations":{},"doi":"10.1002/yea.3660","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2021","pubmed_entrez_date":"2021-07-12","pubmed_publication_date":"Nov 2021","terms_by_termid":{},"title":"Yesprit and Yeaseq: Applications for designing primers and browsing sequences for research using the four Schizosaccharomyces species.","uniquename":"PMID:34251689"}


id: PMID:28228545
data:
  {"abstract":"Inactivation of retrotransposons is accompanied by the emergence of centromere-binding protein-B (CENPB) in  Schizosaccharomyces , as well as in metazoans. The RNA interference (RNAi)-induced transcriptional silencing (RITS) complex, comprising chromodomain protein-1 (Chp1), Tas3 (protein with unknown function), and Argonaute (Ago1), plays an important role in RNAi-mediated heterochromatinization. We find that whereas the Ago1 subunit of the RITS complex is highly conserved, Tas3 is lost and Chp1 is truncated in  Schizosaccharomyces cryophilus  and  Schizosaccharomyces octosporus  We show that truncated Chp1 loses the property of heterochromatin localization and silencing when transformed in  Schizosaccharomyces pombe  Furthermore, multiple copies of CENPB, related to  Tc1/mariner and Tc5  transposons, occur in all  Schizosaccharomyces  species, as well as in humans, but with loss of transposase function (except  Schizosaccharomyces japonicus ). We propose that acquisition of  Tc1/mariner and Tc5  elements by horizontal transfer in  S. pombe  (and humans) is accompanied by alteration of their function from a transposase/endonuclease to a heterochromatin protein, designed to suppress transposon expression and recombination. The resulting redundancy of RITS may have eased the selection pressure, resulting in progressive loss or truncation of  tas3  and  chp1  genes in  S. octosporus  and  S. cryophilus  and triggered similar evolutionary dynamics in the metazoan orthologues.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Upadhyay U, Srivastava S, Khatri I, Nanda JS, Subramanian S, Arora A, Singh J","authors_abbrev":"Upadhyay U et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Phylogeny and evolutionary studies","citation":"Mol Biol Cell 2017 Apr 15;28(8):1132-1146","cv_annotations":{},"doi":"10.1091/mbc.E16-07-0485","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2017","pubmed_entrez_date":"2017-02-24","pubmed_publication_date":"15 Apr 2017","terms_by_termid":{},"title":"Ablation of RNA interference and retrotransposons accompany acquisition and evolution of transposases to heterochromatin protein CENPB.","uniquename":"PMID:28228545"}


id: PMID:30664646
data:
  {"abstract":"Cells of a specific cell type may divide within a certain size range. Yet, functionally optimal cellular organization is typically maintained across different cell sizes, a phenomenon known as scaling. The mechanisms underlying scaling and its physiological significance remain elusive. Here we approach this problem by interfering with scaling in the rod-shaped fission yeast Schizosaccharomyces japonicus that relies on cellular geometry cues to position the division site. We show that S. japonicus uses the Cdc42 polarity module to adjust its geometry to changes in the cell size. When scaling is prevented resulting in abnormal cellular length-to-width aspect ratio, cells exhibit severe division site placement defects. We further show that despite the generally accepted view, a similar scaling phenomenon can occur in the sister species, Schizosaccharomyces pombe. Our results demonstrate that scaling is required for normal cell function and delineate possible rules for cellular geometry maintenance in populations of proliferating cells.","alleles_by_uniquename":{"SJAG_00028:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00028","name":"rga6delta","uniquename":"SJAG_00028:allele-1"},"SJAG_00514:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00514","name":"scd1delta","uniquename":"SJAG_00514:allele-1"},"SJAG_03048:allele-1":{"allele_type":"amino_acid_mutation","description":"G146D","gene_uniquename":"SJAG_03048","name":"cdc2-1w","uniquename":"SJAG_03048:allele-1"},"SJAG_03581:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03581","name":"gef1delta","uniquename":"SJAG_03581:allele-1"},"SJAG_04280:allele-2":{"allele_type":"amino_acid_mutation","description":"T582G","gene_uniquename":"SJAG_04280","name":"wee1-as8","uniquename":"SJAG_04280:allele-2"},"SJAG_04280:allele-3":{"allele_type":"amino_acid_mutation","description":"G788E","gene_uniquename":"SJAG_04280","name":"wee1-G788E","uniquename":"SJAG_04280:allele-3"},"SJAG_04522:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04522","name":"rga4delta","uniquename":"SJAG_04522:allele-1"}},"annotation_curators":[{"annotation_count":3,"community_curator":false,"file_name":null,"file_type":null,"name":"Val Wood","orcid":"0000-0001-6330-7526"},{"annotation_count":22,"community_curator":true,"file_name":null,"file_type":null,"name":"Ying Gu","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-07-02","authors":"Gu Y, Oliferenko S","authors_abbrev":"Gu Y et al.","canto_added_date":"2021-05-10 02:37:31","canto_annotation_status":"APPROVED","canto_approved_date":"2021-09-01 07:53:28","canto_curator_name":"Ying Gu","canto_curator_role":"community","canto_first_approved_date":"2021-07-02 12:32:27","canto_session_key":"0922e2a5229110bd","canto_session_submitted_date":"2021-06-30 22:18:13","canto_triage_status":"Curatable","citation":"Nat Commun 2019 01 21;10(1):268","cv_annotations":{"biological_process":[{"annotations":[114557],"is_not":false,"summary":null,"term":"GO:0061171"},{"annotations":[114558,114559],"is_not":false,"summary":null,"term":"GO:0008360"}],"multi_locus_phenotype":[{"annotations":[114545,114550],"is_not":false,"summary":null,"term":"FYPO:0007783"},{"annotations":[114556],"is_not":false,"summary":null,"term":"FYPO:0004105"},{"annotations":[114547],"is_not":false,"summary":null,"term":"FYPO:0001369"},{"annotations":[114549],"is_not":false,"summary":null,"term":"FYPO:0004293"}],"single_locus_phenotype":[{"annotations":[114551],"is_not":false,"summary":null,"term":"FYPO:0000198"},{"annotations":[114552,114553,114555],"is_not":false,"summary":null,"term":"FYPO:0005503"},{"annotations":[114546],"is_not":false,"summary":null,"term":"FYPO:0007783"},{"annotations":[114540],"is_not":false,"summary":null,"term":"FYPO:0004105"},{"annotations":[114554],"is_not":false,"summary":null,"term":"FYPO:0002870"},{"annotations":[114548],"is_not":false,"summary":null,"term":"FYPO:0001369"},{"annotations":[114541],"is_not":false,"summary":null,"term":"FYPO:0001234"},{"annotations":[114535,114536,114539],"is_not":false,"summary":null,"term":"FYPO:0000648"},{"annotations":[114537,114538,114544],"is_not":false,"summary":null,"term":"FYPO:0001877"},{"annotations":[114542,114543],"is_not":false,"summary":null,"term":"FYPO:0006616"}]},"doi":"10.1038/s41467-018-08218-2","gene_count":8,"genes_by_uniquename":{"SJAG_00028":null,"SJAG_00030":null,"SJAG_00514":null,"SJAG_01794":null,"SJAG_03048":null,"SJAG_03581":null,"SJAG_04280":null,"SJAG_04522":null},"genotypes_by_uniquename":{"cdc2-1w-G146D-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"cdc2-1w(G146D aa)","display_uniquename":"cdc2-1w-G146D-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03048:allele-1","expression":"Not assayed or wild type"}]}]},"gef1delta":{"display_name":"gef1delta","display_uniquename":"gef1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03581:allele-1","expression":"Null"}]}]},"rga4delta":{"display_name":"rga4delta","display_uniquename":"rga4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]}]},"rga4delta__rga6delta":{"display_name":"rga4delta rga6delta","display_uniquename":"rga4delta__rga6delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_00028:allele-1","expression":"Null"}]}]},"rga4delta__wee1-G788E-G788E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"rga4delta wee1-G788E(aa)","display_uniquename":"rga4delta__wee1-G788E-G788E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-3","expression":"Not assayed or wild type"}]}]},"rga4delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"rga4delta wee1-as8(T582G aa)","display_uniquename":"rga4delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]},"rga6delta":{"display_name":"rga6delta","display_uniquename":"rga6delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00028:allele-1","expression":"Null"}]}]},"rga6delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"rga6delta wee1-as8(T582G aa)","display_uniquename":"rga6delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00028:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]},"scd1delta":{"display_name":"scd1delta","display_uniquename":"scd1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00514:allele-1","expression":"Null"}]}]},"wee1-G788E-G788E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"wee1-G788E(aa)","display_uniquename":"wee1-G788E-G788E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-3","expression":"Not assayed or wild type"}]}]},"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"wee1-as8(T582G aa)","display_uniquename":"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]}},"ltp_gene_count":6,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2019","pubmed_entrez_date":"2019-01-22","pubmed_publication_date":"21 01 2019","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000005":null,"FYECO:0000006":null,"FYECO:0000103":null,"FYECO:0000126":null,"FYECO:0000137":null,"FYECO:0000338":null,"FYPO:0000198":null,"FYPO:0000648":null,"FYPO:0001234":null,"FYPO:0001369":null,"FYPO:0001877":null,"FYPO:0002870":null,"FYPO:0004105":null,"FYPO:0004293":null,"FYPO:0005503":null,"FYPO:0006616":null,"FYPO:0007783":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null,"GO:0008360":null,"GO:0061171":null},"title":"Cellular geometry scaling ensures robust division site positioning.","uniquename":"PMID:30664646"}


id: PMID:12402243
data:
  {"abstract":"The structure and localization of the microtubule organization centres (MTOCs) of the fission yeast Schizosaccharomyces japonicus var. japonicus were examined by fluorescence microscopy and electron microscopy. Spindle pole bodies (SPBs), which are the fungal equivalent of centrosomes, of Sz. japonicus were visualized by immunofluorescent staining using a monoclonal anti-gamma-tubulin antibody. The behaviour of the SPBs during the cell cycle mostly coincided with previous reports on the most widely used fission yeast Schizosaccharomyces pombe. We cloned the gamma-tubulin gene from Sz. japonicus by PCR using redundant sets of primers corresponding to conserved regions of known gamma-tubulins. The predicted amino acid sequence of Sz. japonicus gamma-tubulin was most similar to the Sz. pombe gamma-tubulin. Under the electron microscope, the SPBs of Sz. japonicus were detected as electron-dense multilayered structures located just outside the nuclear envelope. The SPBs of Sz. japonicus were composed of three electron-dense layers and were surrounded by fuzzy material. Each layer showed structural changes according to the progression of the cell cycle. In mitotic cells, the SPBs were located on the fenestrae of the nuclear envelopes through which the mitotic spindle microtubules ran into the nucleoplasm. Our results show that Sz. japonicus is a very potent and attractive organism for the investigation of the microtubule nucleation system and morphogenesis in yeasts. The Accession No. for the nucleotide sequence of the Sz. japonicus gtb1(+) gene is AF159163.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Horio T, Kimura N, Basaki A, Tanaka Y, Noguchi T, Akashi T, Tanaka K","authors_abbrev":"Horio T et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Sequence feature or region","citation":"Yeast 2002 Nov;19(15):1335-50","cv_annotations":{},"gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2002","pubmed_entrez_date":"2002-10-29","pubmed_publication_date":"Nov 2002","terms_by_termid":{},"title":"Molecular and structural characterization of the spindle pole bodies in the fission yeast Schizosaccharomyces japonicus var japonicus.","uniquename":"PMID:12402243"}


id: PMID:22641476
data:
  {"abstract":"Measuring relative genetic distances is one of the best ways to locate genetic loci. Here we report the construction of a strains set for genetic mapping in Schizosaccharomyces japonicus, which belongs to the genus Schizosaccharomyces together with the well-studied fission yeast Sz. pombe. We constructed 29 strains that bear a positive-negative selection marker at different loci. The marker was inserted every 500 kb in the genome of Sz. japonicus. Each marker thus becomes a 'scale mark' of a chromosome that behaves like a yardstick. By determining the genetic distances from the inserted markers, the relative location of a genomic mutation can be determined. We also constructed a fosmid library that covers an entire genome of Sz. japonicus. These tools together would facilitate identification and cloning of the gene.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Furuya K, Aoki K, Niki H","authors_abbrev":"Furuya K et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Method or reagent","citation":"Yeast 2012 Jun;29(6):241-9","cv_annotations":{},"doi":"10.1002/yea.2907","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2012","pubmed_entrez_date":"2012-05-30","pubmed_publication_date":"Jun 2012","terms_by_termid":{},"title":"Construction of an insertion marker collection of Sz. japonicus (IMACS) for genetic mapping and a fosmid library covering its genome.","uniquename":"PMID:22641476"}


id: PMID:36058798
data:
  {"abstract":"Schizosaccharomyces japonicus is a dimorphic yeast, transiting between unicellular and hyphal growth. The glycoproteins of fission yeast contain, in addition to mannose (Man), a large number of galactose (Gal) residues. Previously, we reported that the cell-surface O-glycans of S. japonicus comprise mainly tri-saccharides (Gal-Man-Man) as a main component, in contrast to the tetra-saccharides observed in other Schizosaccharomyces species. Here we have investigated the function of cell-surface Gal residues in S. japonicus. Because disruption of gms1 + , encoding the UDP-Gal transporter required for galactomannan synthesis, abolishes cell-surface galactosylation in Schizosaccharomyces pombe, we constructed a deletion mutant of the homologous gene in S. japonicus gms1Δ [gms1 (S.j)] and determined the N- and O-linked oligosaccharide structures present on the cell surface. Disruption of gms1 (S.j) resulted in a complete lack of Gal on the cell surface, indicating that Gms1 plays an essential role in supplying UDP-Gal from the cytoplasm to the Golgi lumen. Analytical microscopy of gms1Δ demonstrated that the lack of cell-surface Gal did not affect cell growth or morphology during vegetative growth. However, hyphal development was blocked in gms1Δ, even in the presence of the topoisomerase I inhibitor camptothecin, which is known to induce hyphal differentiation in wild-type S. japonicus. Collectively, these findings show that Gal-containing oligosaccharides are required for cell wall integrity during filamentous growth in S. japonicus.","alleles_by_uniquename":{"SJAG_04697:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04697","name":"gms1delta","uniquename":"SJAG_04697:allele-1"}},"annotation_curators":[{"annotation_count":6,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":"0000-0002-8138-6851"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2022-12-01","authors":"Fukunaga T, Ohashi T, Tanaka Y, Yoshimatsu T, Higuchi Y, Maekawa H, Takegawa K","authors_abbrev":"Fukunaga T et al.","canto_added_date":"2022-11-25 12:12:27","canto_annotation_status":"APPROVED","canto_approved_date":"2022-12-01 10:35:53","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2022-12-01 10:35:53","canto_session_key":"465355706dc223a3","canto_session_submitted_date":"2022-11-25 12:49:07","canto_triage_status":"Curatable","citation":"J Biosci Bioeng 2022 Nov;134(5):384-392","cv_annotations":{"single_locus_phenotype":[{"annotations":[114658],"is_not":false,"summary":null,"term":"FYPO:0008029"},{"annotations":[114654],"is_not":false,"summary":null,"term":"FYPO:0000082"},{"annotations":[114657],"is_not":false,"summary":null,"term":"FYPO:0007776"},{"annotations":[114656],"is_not":false,"summary":null,"term":"FYPO:0007780"},{"annotations":[114653],"is_not":false,"summary":null,"term":"FYPO:0003727"},{"annotations":[114655],"is_not":false,"summary":null,"term":"FYPO:0000106"}]},"doi":"10.1016/j.jbiosc.2022.07.014","gene_count":1,"genes_by_uniquename":{"SJAG_04697":null},"genotypes_by_uniquename":{"gms1delta":{"display_name":"gms1delta","display_uniquename":"gms1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04697:allele-1","expression":"Null"}]}]}},"ltp_gene_count":1,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2022","pubmed_entrez_date":"2022-09-04","pubmed_publication_date":"Nov 2022","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000005":null,"FYECO:0000126":null,"FYECO:0000137":null,"FYECO:0000314":null,"FYPO:0000082":null,"FYPO:0000106":null,"FYPO:0003727":null,"FYPO:0007776":null,"FYPO:0007780":null,"FYPO:0008029":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null},"title":"Galactosylation of cell-surface glycoprotein required for hyphal growth and cell wall integrity in Schizosaccharomyces japonicus.","uniquename":"PMID:36058798"}


id: PMID:33791858
data:
  {"abstract":"Mitogen-activated protein kinase (MAPK) signalling pathways regulate multiple cellular functions in eukaryotic organisms in response to environmental cues, including the dynamic remodeling of the actin cytoskeleton. The fission yeast S. pombe is an optimal model to investigate the conserved regulatory mechanisms of cytokinesis, which relies in an actomyosin-based contractile ring (CAR) that prompts the physical separation of daughter cells during cellular division. Our group has recently shown that p38 MAPK ortholog Sty1, the core component of the stress-activated pathway (SAPK), negatively modulates CAR assembly and integrity in S. pombe during actin cytoskeletal damage induced with Latrunculin A and in response to environmental stress. This response involves downregulation of protein levels of the formin For3, which assembles actin filaments for cables and the CAR, likely through an ubiquitin-mediated degradation mechanism. Contrariwise, Sty1 function positively reinforces CAR assembly during stress in the close relative dimorphic fission yeast S. japonicus. The opposite effect of SAPK signaling on CAR integrity may represent an evolutionary refined adaptation to cope with the marked differences in cytokinesis onset in both fission yeast species.","alleles_by_uniquename":{"SJAG_00266:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00266","name":"atf1delta","uniquename":"SJAG_00266:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"}},"annotation_curators":[{"annotation_count":4,"community_curator":true,"file_name":null,"file_type":null,"name":"Elisa Gómez Gil","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-09-14","authors":"Madrid M, Gómez-Gil E, Cansado J","authors_abbrev":"Madrid M et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2021-09-14 21:24:28","canto_curator_name":"Elisa Gómez Gil","canto_curator_role":"community","canto_first_approved_date":"2021-09-14 21:24:28","canto_session_key":"84ac20b0ff20a3cd","canto_session_submitted_date":"2021-09-14 16:45:32","canto_triage_status":"Curatable","citation":"Curr Genet 2021 Oct;67(5):715-721","cv_annotations":{"PSI-MOD":[{"annotations":[114139],"is_not":false,"summary":null,"term":"MOD:00696"}],"single_locus_phenotype":[{"annotations":[114138],"is_not":false,"summary":null,"term":"FYPO:0002998"},{"annotations":[114136,114137],"is_not":false,"summary":null,"term":"FYPO:0000107"}]},"doi":"10.1007/s00294-021-01155-6","gene_count":2,"genes_by_uniquename":{"SJAG_00266":null,"SJAG_02592":null},"genotypes_by_uniquename":{"atf1delta":{"display_name":"atf1delta","display_uniquename":"atf1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00266:allele-1","expression":"Null"}]}]},"sty1delta":{"display_name":"sty1delta","display_uniquename":"sty1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02592:allele-1","expression":"Null"}]}]}},"ltp_gene_count":2,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2021","pubmed_entrez_date":"2021-04-01","pubmed_publication_date":"Oct 2021","terms_by_termid":{"FYECO:0000248":null,"FYPO:0000107":null,"FYPO:0002998":null,"FYPO_EXT:0000001":null,"GO:0120306":null,"MOD:00696":null},"title":"Negative control of cytokinesis by stress-activated MAPK signaling.","uniquename":"PMID:33791858"}


id: PMID:21733045
data:
  {"abstract":"During open mitosis in higher eukaryotic cells, the nuclear envelope completely breaks down and then mitotic chromosomes are exposed in the cytoplasm. By contrast, mitosis in lower eukaryotes, including fungi, proceeds with the nucleus enclosed in an intact nuclear envelope. The mechanism of mitosis has been studied extensively in yeast, a closed mitosis organism. Here, we describe a form of mitosis in which the nuclear envelope is torn by elongation of the nucleus in the fission yeast Schizosaccharomyces japonicus. The mitotic nucleus of Sz. japonicus adopted a fusiform shape in anaphase, and its following extension caused separation. Finally, a tear in the nuclear envelope occurred in late anaphase. At the same time, a polarized-biased localization of nuclear pores was seen in the fusiform-shaped nuclear envelope, suggesting a compromise in the mechanical integrity of the lipid membrane. It has been known that nuclear membrane remains intact in some metazoan mitosis. We found that a similar tear of the nuclear envelope was also observed in late mitosis of the Caenorhabditis elegans embryo. These findings provide insight into the diversity of mitosis and the biological significance of breakdown of the nuclear envelope.","alleles_by_uniquename":{},"annotation_curators":[{"annotation_count":2,"community_curator":true,"file_name":null,"file_type":null,"name":"Sho Okamoto","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2022-11-21","authors":"Aoki K, Hayashi H, Furuya K, Sato M, Takagi T, Osumi M, Kimura A, Niki H","authors_abbrev":"Aoki K et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2022-11-21 17:28:56","canto_curator_name":"Sho Okamoto","canto_curator_role":"community","canto_first_approved_date":"2022-11-21 17:28:56","canto_session_key":"6063f08db89b54c7","canto_session_submitted_date":"2022-11-21 17:28:46","canto_triage_status":"Curatable","citation":"Genes Cells 2011 Sep;16(9):911-26","cv_annotations":{"cellular_component":[{"annotations":[114208],"is_not":false,"summary":null,"term":"GO:0070762"},{"annotations":[114209],"is_not":false,"summary":null,"term":"GO:0005816"}]},"doi":"10.1111/j.1365-2443.2011.01540.x","gene_count":1,"genes_by_uniquename":{"SJAG_03200":null},"genotypes_by_uniquename":{},"ltp_gene_count":1,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2011","pubmed_entrez_date":"2011-07-08","pubmed_publication_date":"Sep 2011","terms_by_termid":{"GO:0005816":null,"GO:0070762":null},"title":"Breakage of the nuclear envelope by an extending mitotic nucleus occurs during anaphase in Schizosaccharomyces japonicus.","uniquename":"PMID:21733045"}


id: PMID:24699070
data:
  {"abstract":"The post-cytokinetic separation of cells in cell-walled organisms involves enzymic processes that degrade a specific layer of the division septum and the region of the mother cell wall that edges the septum. In the fission yeast Schizosaccharomyces pombe, the 1,3-α-glucanase Agn1p, originally identified as a mutanase-like glycoside hydrolase family 71 (GH71) enzyme, dissolves the mother cell wall around the septum edge. Our search in the genomes of completely sequenced fungi identified GH71 hydrolases in Basidiomycota, Taphrinomycotina and Pezizomycotina, but not in Saccharomycotina. The most likely Agn1p orthologues in Pezizomycotina species are not mutanases having mutanase-binding domains, but experimentally non-characterized hypothetical proteins that have no carbohydrate-binding domains. The analysis of the GH71 domains corroborated the phylogenetic relationships of the Schizosaccharomyces species determined by previous studies, but suggested a closer relationship to the Basidiomycota proteins than to the Ascomycota proteins. In the Schizosaccharomyces genus, the Agn1p proteins are structurally conserved: their GH71 domains are flanked by N-terminal secretion signals and C-terminal sequences containing the conserved block YNFNA(Y)/HTG. The inactivation of the agn1(Sj) gene in Schizosaccharomyces japonicus, the only true dimorphic member of the genus, caused a severe cell-separation defect in its yeast phase, but had no effect on the hyphal growth and yeast-to-mycelium transition. It did not affect the mycelium-to-yeast transition either, only delaying the separation of the yeast cells arising from the fragmenting hyphae. The heterologous expression of agn1(Sj) partially rescued the separation defect of the agn1Δ cells of Schizosaccharomyces pombe. The results presented indicate that the fission yeast Agn1p 1,3-α-glucanases of Schizosaccharomyces japonicus and Schizosaccharomyces pombe share conserved functions in the yeast phase. ","alleles_by_uniquename":{"SJAG_03444:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03444","name":"agn1delta","uniquename":"SJAG_03444:allele-1"}},"annotation_curators":[{"annotation_count":1,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":"0000-0002-8138-6851"},{"annotation_count":1,"community_curator":false,"file_name":null,"file_type":null,"name":"Val Wood","orcid":"0000-0001-6330-7526"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-07-09","authors":"Sipiczki M, Balazs A, Monus A, Papp L, Horvath A, Sveiczer A, Miklos I","authors_abbrev":"Sipiczki M et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2021-09-01 07:35:20","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-07-09 13:16:43","canto_session_key":"b8bc1733e6f2c600","canto_session_submitted_date":"2021-07-09 13:16:35","canto_triage_status":"Curatable","citation":"Microbiology (Reading) 2014 Jun;160(Pt 6):1063-1074","cv_annotations":{"biological_process":[{"annotations":[114632],"is_not":false,"summary":null,"term":"GO:0030995"}],"single_locus_phenotype":[{"annotations":[114631],"is_not":false,"summary":null,"term":"FYPO:0001971"}]},"doi":"10.1099/mic.0.077511-0","gene_count":1,"genes_by_uniquename":{"SJAG_03444":null},"genotypes_by_uniquename":{"agn1delta":{"display_name":"agn1delta","display_uniquename":"agn1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03444:allele-1","expression":"Null"}]}]}},"ltp_gene_count":1,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2014","pubmed_entrez_date":"2014-04-05","pubmed_publication_date":"Jun 2014","terms_by_termid":{"FYPO:0001971":null,"GO:0030995":null},"title":"Phylogenetic and comparative functional analysis of the cell-separation α-glucanase Agn1p in Schizosaccharomyces.","uniquename":"PMID:24699070"}


id: PMID:31380845
data:
  {"abstract":"Lipid metabolism and its regulation are of interest to both basic and applied life sciences and biotechnology. In this regard, various yeast species are used as models in lipid metabolic research or for industrial lipid production. Lipid droplets are highly dynamic storage bodies and their cellular content represents a convenient readout of the lipid metabolic state. Fluorescence microscopy is a method of choice for quantitative analysis of cellular lipid droplets, as it relies on widely available equipment and allows analysis of individual lipid droplets. Furthermore, microscopic image analysis can be automated, greatly increasing overall analysis throughput. Here, we describe an experimental and analytical workflow for automated detection and quantitative description of individual lipid droplets in three different model yeast species: the fission yeasts Schizosaccharomyces pombe and Schizosaccharomyces japonicus, and the budding yeast Saccharomyces cerevisiae. Lipid droplets are visualized with BODIPY 493/503, and cell-impermeable fluorescent dextran is added to the culture media to help identify cell boundaries. Cells are subjected to 3D epifluorescence microscopy in green and blue channels and the resulting z-stack images are processed automatically by a MATLAB pipeline. The procedure outputs rich quantitative data on cellular lipid droplet content and individual lipid droplet characteristics in a tabular format suitable for downstream analyses in major spreadsheet or statistical packages. We provide example analyses of lipid droplet content under various conditions that affect cellular lipid metabolism.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Princová J, Schätz M, Ťupa O, Převorovský M","authors_abbrev":"Princová J et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Method or reagent","citation":"J Vis Exp 2019 07 17;(149)","cv_annotations":{},"doi":"10.3791/59889","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2019","pubmed_entrez_date":"2019-08-06","pubmed_publication_date":"17 07 2019","terms_by_termid":{},"title":"Analysis of Lipid Droplet Content in Fission and Budding Yeasts using Automated Image Processing.","uniquename":"PMID:31380845"}


id: PMID:20737410
data:
  {"abstract":"Schizosaccharomyces japonicus is a fission yeast for which new genetic tools have recently been developed. Here, we report novel plasmid vectors with high transformation efficiency and an electroporation method for Sz. japonicus. We isolated 44 replicating segments from 12 166 transformants of Sz. japonicus genomic fragments and found a chromosomal fragment, RS1, as a new replicating sequence that conferred high transformation activity to Sz. japonicus cells. This sequence was cloned into a pUC19 vector with ura4(+) of Sz. pombe (pSJU11) or the kan gene on the kanMX6 module (pSJK11) as selection markers. These plasmids transformed Sz. japonicus cells in the early-log phase by electroporation at a frequency of 123 cfu/µg for pSJK11 and 301 cfu/µg for pSJU11, which were higher than previously reported autonomously replicating sequences. Although a portion of plasmids remained in host cells by integration into the chromosome via RS1 segment, the plasmids could be recovered from transformants. The plasmid copy number was estimated to be 1.88 copies per cell by Southern blot analysis using a Sz. pombe ura4(+) probe. The plasmid containing ade6(+) suppressed the auxotrophic growth of the ade6-domE mutant, indicating that the plasmid would be useful for suppressor screening and complementation assays in Sz. japonicus. Furthermore, pSJU11 transformed Sz. pombe cells with the same frequency as the pREP2 plasmid. This study is a report to demonstrate practical use of episomal plasmid vectors for genetic research in Sz. japonicus.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Aoki K, Nakajima R, Furuya K, Niki H","authors_abbrev":"Aoki K et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Method or reagent","citation":"Yeast 2010 Dec;27(12):1049-60","cv_annotations":{},"doi":"10.1002/yea.1815","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2010","pubmed_entrez_date":"2010-08-26","pubmed_publication_date":"Dec 2010","terms_by_termid":{},"title":"Novel episomal vectors and a highly efficient transformation procedure for the fission yeast Schizosaccharomyces japonicus.","uniquename":"PMID:20737410"}


id: PMID:27734801
data:
  {"abstract":"Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown mechanism. Here we find in  Schizosaccharomyces japonicus  and  Schizosaccharomyces pombe  that, during actomyosin ring contraction, actin filaments associated with actomyosin rings are expelled as micron-scale bundles containing multiple actomyosin ring proteins. Using functional isolated actomyosin rings we show that expulsion of actin bundles does not require continuous presence of cytoplasm. Strikingly, mechanical compression of actomyosin rings results in expulsion of bundles predominantly at regions of high curvature. Our work unprecedentedly reveals that the increased curvature of the ring itself promotes its disassembly. It is likely that such a curvature-induced mechanism may operate in disassembly of other contractile networks.","alleles_by_uniquename":{},"annotation_curators":[{"annotation_count":2,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":"0000-0002-8138-6851"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-07-09","authors":"Huang J, Chew TG, Gu Y, Palani S, Kamnev A, Martin DS, Carter NJ, Cross RA, Oliferenko S, Balasubramanian MK","authors_abbrev":"Huang J et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2021-07-09 15:10:46","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-07-09 15:10:46","canto_session_key":"f47401f00ac444e0","canto_session_submitted_date":"2021-07-09 15:10:39","canto_triage_status":"Curatable","citation":"Elife 2016 10 13;5","cv_annotations":{"cellular_component":[{"annotations":[114504],"is_not":false,"summary":null,"term":"GO:0032432"},{"annotations":[114503],"is_not":false,"summary":null,"term":"GO:0005826"}]},"doi":"10.7554/eLife.21383","gene_count":1,"genes_by_uniquename":{"SJAG_04887":null},"genotypes_by_uniquename":{},"ltp_gene_count":1,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2016","pubmed_entrez_date":"2016-10-14","pubmed_publication_date":"13 10 2016","terms_by_termid":{"GO:0005826":null,"GO:0032432":null},"title":"Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction.","uniquename":"PMID:27734801"}


id: GO_REF:0000117
data:
  {"alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"canto_curator_role":"JaponicusDB","cv_annotations":{"biological_process":[{"annotations":[58399],"is_not":false,"summary":null,"term":"GO:0016043"},{"annotations":[59326,65187,68606],"is_not":false,"summary":null,"term":"GO:0006338"},{"annotations":[59323],"is_not":false,"summary":null,"term":"GO:0006281"},{"annotations":[68701],"is_not":false,"summary":null,"term":"GO:0016197"},{"annotations":[63966],"is_not":false,"summary":null,"term":"GO:0051649"},{"annotations":[67300],"is_not":false,"summary":null,"term":"GO:0061157"},{"annotations":[59482],"is_not":false,"summary":null,"term":"GO:0022613"},{"annotations":[68322],"is_not":false,"summary":null,"term":"GO:0044281"},{"annotations":[58973,66265],"is_not":false,"summary":null,"term":"GO:0006772"}],"cellular_component":[{"annotations":[60398],"is_not":false,"summary":null,"term":"GO:0005680"},{"annotations":[63031,65577],"is_not":false,"summary":null,"term":"GO:0005938"},{"annotations":[65578],"is_not":false,"summary":null,"term":"GO:0032153"},{"annotations":[56711,57126],"is_not":false,"summary":null,"term":"GO:0005737"},{"annotations":[59325,65186],"is_not":false,"summary":null,"term":"GO:0043229"},{"annotations":[62352],"is_not":false,"summary":null,"term":"GO:0016020"}],"molecular_function":[{"annotations":[62353],"is_not":false,"summary":null,"term":"GO:0005375"},{"annotations":[65579],"is_not":false,"summary":null,"term":"GO:0005096"},{"annotations":[59327],"is_not":false,"summary":null,"term":"GO:0097159"},{"annotations":[61493],"is_not":false,"summary":null,"term":"GO:0004521"},{"annotations":[69603],"is_not":false,"summary":null,"term":"GO:0022857"}]},"gene_count":20,"genes_by_uniquename":{"SJAG_00551":null,"SJAG_00773":null,"SJAG_00907":null,"SJAG_01119":null,"SJAG_01666":null,"SJAG_01742":null,"SJAG_01869":null,"SJAG_01943":null,"SJAG_02047":null,"SJAG_02156":null,"SJAG_02162":null,"SJAG_02725":null,"SJAG_02986":null,"SJAG_03058":null,"SJAG_03675":null,"SJAG_04329":null,"SJAG_04772":null,"SJAG_05161":null,"SJAG_06608":null,"SJAG_06641":null},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"terms_by_termid":{"GO:0004521":null,"GO:0005096":null,"GO:0005375":null,"GO:0005680":null,"GO:0005737":null,"GO:0005938":null,"GO:0006281":null,"GO:0006338":null,"GO:0006772":null,"GO:0016020":null,"GO:0016043":null,"GO:0016197":null,"GO:0022613":null,"GO:0022857":null,"GO:0032153":null,"GO:0043229":null,"GO:0044281":null,"GO:0051649":null,"GO:0061157":null,"GO:0097159":null},"uniquename":"GO_REF:0000117"}


id: PMID:22531001
data:
  {"abstract":"DNA replication initiates at distinct origins in eukaryotic genomes, but the genomic features that define these sites are not well understood.\nWe have taken a combined experimental and bioinformatic approach to identify and characterize origins of replication in three distantly related fission yeasts: Schizosaccharomyces pombe, Schizosaccharomyces octosporus and Schizosaccharomyces japonicus. Using single-molecule deep sequencing to construct amplification-free high-resolution replication profiles, we located origins and identified sequence motifs that predict origin function. We then mapped nucleosome occupancy by deep sequencing of mononucleosomal DNA from the corresponding species, finding that origins tend to occupy nucleosome-depleted regions.\nThe sequences that specify origins are evolutionarily plastic, with low complexity nucleosome-excluding sequences functioning in S. pombe and S. octosporus, and binding sites for trans-acting nucleosome-excluding proteins functioning in S. japonicus. Furthermore, chromosome-scale variation in replication timing is conserved independently of origin location and via a mechanism distinct from known heterochromatic effects on origin function. These results are consistent with a model in which origins are simply the nucleosome-depleted regions of the genome with the highest affinity for the origin recognition complex. This approach provides a general strategy for understanding the mechanisms that define DNA replication origins in eukaryotes.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Xu J, Yanagisawa Y, Tsankov AM, Hart C, Aoki K, Kommajosyula N, Steinmann KE, Bochicchio J, Russ C, Regev A, Rando OJ, Nusbaum C, Niki H, Milos P, Weng Z, Rhind N","authors_abbrev":"Xu J et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Sequence feature or region","citation":"Genome Biol 2012 Apr 24;13(4):R27","cv_annotations":{},"doi":"10.1186/gb-2012-13-4-r27","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2012","pubmed_entrez_date":"2012-04-26","pubmed_publication_date":"24 Apr 2012","terms_by_termid":{},"title":"Genome-wide identification and characterization of replication origins by deep sequencing.","uniquename":"PMID:22531001"}


id: PMID:9720056
data:
  {"abstract":"The cells of Schizosaccharomyces japonicus var. versatilis responded to the presence of cytochalasin D (CD), an inhibitor of actin polymerization, by the disappearance of contractile actin rings (ARs) that had already formed and by inhibition of new ring formation. Actin cables disappeared. Actin patches remained preserved and became co-localized with regions of actual cell wall formation (at cell poles and at the site of septum development). Removal of the AR arrested formation of the primary septum and led to the production of aberrant septum protrusions in that region. Nuclear division was accomplished in the presence of CD but new ARs were not produced. The wall (septum) material was deposited in the form of a wide band at the inner surface of the lateral cell wall in the cell centre. This layer showed a thin fibrillar structure. The removal of CD resulted in rapid formation of new ARs in the equatorial region of the cells. This implies that the signal for AR localization was not abolished either by CD effects or by removal of an AR already formed. Some of the newly developed ARs showed atypical localization and orientation. In addition, redundant, subcortically situated actin bundles were produced. The removal of CD was quickly followed by the development of primary septa co-localized with ARs. Wall protrusions occurred co-localized with the redundant actin bundles. If these were completed in a circle, redundant septa developed. The AR is a mechanism which, in time and space, triggers cytokinesis by building a septum sequentially dependent on the AR. Aberrant septa were not capable of separating daughter cells. However, non-separated daughter cells subsequently gave rise to normal cells.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Gabriel M, Horký D, Svoboda A, Kopecká M","authors_abbrev":"Gabriel M et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Cell composition or WT feature","citation":"Microbiology (Reading) 1998 Aug;144 ( Pt 8):2331-2344","cv_annotations":{},"doi":"10.1099/00221287-144-8-2331","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"1998","pubmed_entrez_date":"1998-08-28","pubmed_publication_date":"Aug 1998","terms_by_termid":{},"title":"Cytochalasin D interferes with contractile actin ring and septum formation in Schizosaccharomyces japonicus var. versatilis.","uniquename":"PMID:9720056"}


id: PMID:37164017
data:
  {"abstract":"Most eukaryotes respire oxygen, using it to generate biomass and energy. However, a few organisms have lost the capacity to respire. Understanding how they manage biomass and energy production may illuminate the critical points at which respiration feeds into central carbon metabolism and explain possible routes to its optimization. Here, we use two related fission yeasts, Schizosaccharomyces pombe and Schizosaccharomyces japonicus, as a comparative model system. We show that although S. japonicus does not respire oxygen, unlike S. pombe, it is capable of efficient NADH oxidation, amino acid synthesis, and ATP generation. We probe possible optimization strategies through the use of stable isotope tracing metabolomics, mass isotopologue distribution analysis, genetics, and physiological experiments. S. japonicus appears to have optimized cytosolic NADH oxidation via glycerol-3-phosphate synthesis. It runs a fully bifurcated TCA pathway, sustaining amino acid production. Finally, we propose that it has optimized glycolysis to maintain high ATP/ADP ratio, in part by using the pentose phosphate pathway as a glycolytic shunt, reducing allosteric inhibition of glycolysis and supporting biomass generation. By comparing two related organisms with vastly different metabolic strategies, our work highlights the versatility and plasticity of central carbon metabolism in eukaryotes, illuminating critical adaptations supporting the preferential use of glycolysis over oxidative phosphorylation.","alleles_by_uniquename":{"SJAG_00409:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00409","name":"gpd1delta","uniquename":"SJAG_00409:allele-1"},"SJAG_00601:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00601","name":"rip1delta","uniquename":"SJAG_00601:allele-1"},"SJAG_01355:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01355","name":"cox6delta","uniquename":"SJAG_01355:allele-1"},"SJAG_01753:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01753","name":"mdh1delta","uniquename":"SJAG_01753:allele-1"},"SJAG_02796:allele-1":{"allele_type":"amino_acid_mutation","description":"A343T","gene_uniquename":"SJAG_02796","name":"pyk1-A343T","uniquename":"SJAG_02796:allele-1"},"SJAG_03920:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03920","name":"sdh3delta","uniquename":"SJAG_03920:allele-1"},"SJAG_04843:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04843","name":"fum1delta","uniquename":"SJAG_04843:allele-1"}},"annotation_curators":[{"annotation_count":20,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2023-05-18","authors":"Alam S, Gu Y, Reichert P, Bähler J, Oliferenko S","authors_abbrev":"Alam S et al.","canto_added_date":"2023-05-12 00:40:04","canto_annotation_status":"APPROVED","canto_approved_date":"2023-05-18 12:11:55","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2023-05-18 12:11:54","canto_session_key":"94bcbfb72cf94809","canto_session_submitted_date":"2023-05-18 12:11:43","canto_triage_status":"Curatable","citation":"Curr Biol 2023 Apr 30;","cv_annotations":{"single_locus_phenotype":[{"annotations":[114648],"is_not":false,"summary":null,"term":"FYPO:0007363"},{"annotations":[114646],"is_not":false,"summary":null,"term":"FYPO:0000026"},{"annotations":[114645],"is_not":false,"summary":null,"term":"FYPO:0001355"},{"annotations":[114647],"is_not":false,"summary":null,"term":"FYPO:0001489"},{"annotations":[114649],"is_not":false,"summary":null,"term":"FYPO:0004165"},{"annotations":[114643,114644],"is_not":false,"summary":null,"term":"FYPO:0007790"},{"annotations":[114637,114640],"is_not":false,"summary":null,"term":"FYPO:0000760"},{"annotations":[114639,114642],"is_not":false,"summary":null,"term":"FYPO:0000579"},{"annotations":[114638,114641],"is_not":false,"summary":null,"term":"FYPO:0000590"},{"annotations":[114634,114635,114636],"is_not":false,"summary":null,"term":"FYPO:0001357"},{"annotations":[114633],"is_not":false,"summary":null,"term":"FYPO:0001234"},{"annotations":[114650,114651,114652],"is_not":false,"summary":null,"term":"FYPO:0002058"}]},"doi":"10.1016/j.cub.2023.04.046","gene_count":7,"genes_by_uniquename":{"SJAG_00409":null,"SJAG_00601":null,"SJAG_01355":null,"SJAG_01753":null,"SJAG_02796":null,"SJAG_03920":null,"SJAG_04843":null},"genotypes_by_uniquename":{"cox6delta":{"display_name":"cox6delta","display_uniquename":"cox6delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01355:allele-1","expression":"Null"}]}]},"fum1delta":{"display_name":"fum1delta","display_uniquename":"fum1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04843:allele-1","expression":"Null"}]}]},"gpd1delta":{"display_name":"gpd1delta","display_uniquename":"gpd1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00409:allele-1","expression":"Null"}]}]},"mdh1delta":{"display_name":"mdh1delta","display_uniquename":"mdh1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01753:allele-1","expression":"Null"}]}]},"pyk1-A343T-A343T-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"pyk1-A343T(aa)","display_uniquename":"pyk1-A343T-A343T-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02796:allele-1","expression":"Not assayed or wild type"}]}]},"rip1delta":{"display_name":"rip1delta","display_uniquename":"rip1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00601:allele-1","expression":"Null"}]}]},"sdh3delta":{"display_name":"sdh3delta","display_uniquename":"sdh3delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03920:allele-1","expression":"Null"}]}]}},"ltp_gene_count":7,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2023","pubmed_entrez_date":"2023-05-10","pubmed_publication_date":"30 Apr 2023","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000015":null,"FYECO:0000126":null,"FYECO:0000137":null,"FYPO:0000026":null,"FYPO:0000579":null,"FYPO:0000590":null,"FYPO:0000760":null,"FYPO:0001234":null,"FYPO:0001355":null,"FYPO:0001357":null,"FYPO:0001489":null,"FYPO:0002058":null,"FYPO:0004165":null,"FYPO:0007363":null,"FYPO:0007790":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null,"FYPO_EXT:0000003":null},"title":"Optimization of energy production and central carbon metabolism in a non-respiring eukaryote.","uniquename":"PMID:37164017"}


id: PMID:25318672
data:
  {"abstract":"Excess fatty acids and sterols are stored as triacylglycerols and sterol esters in specialized cellular organelles, called lipid droplets. Understanding what determines the cellular amount of neutral lipids and their packaging into lipid droplets is of fundamental and applied interest. Using two species of fission yeast, we show that cycling cells deficient in the function of the ER-resident CDP-DG synthase Cds1 exhibit markedly increased triacylglycerol content and assemble large lipid droplets closely associated with the ER membranes. We demonstrate that these unusual structures recruit the triacylglycerol synthesis machinery and grow by expansion rather than by fusion. Our results suggest that interfering with the CDP-DG route of phosphatidic acid utilization rewires cellular metabolism to adopt a triacylglycerol-rich lifestyle reliant on the Kennedy pathway. ","alleles_by_uniquename":{"SJAG_00426:allele-1":{"allele_type":"amino_acid_mutation","description":"P363S","gene_uniquename":"SJAG_00426","name":"bbl1-P363S","uniquename":"SJAG_00426:allele-1"}},"annotation_curators":[{"annotation_count":8,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":"0000-0002-8138-6851"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-05-17","authors":"He Y, Yam C, Pomraning K, Chin JS, Yew JY, Freitag M, Oliferenko S","authors_abbrev":"He Y et al.","canto_added_date":"2021-05-10 02:38:06","canto_annotation_status":"APPROVED","canto_approved_date":"2021-05-17 12:42:41","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-05-17 12:42:41","canto_session_key":"f89ee2d26032c510","canto_session_submitted_date":"2021-05-17 12:42:28","canto_triage_status":"Curatable","citation":"Mol Biol Cell 2014 Dec 15;25(25):4083-95","cv_annotations":{"biological_process":[{"annotations":[114339],"is_not":false,"summary":null,"term":"GO:0016024"}],"cellular_component":[{"annotations":[114340],"is_not":false,"summary":null,"term":"GO:0005783"}],"molecular_function":[{"annotations":[114338],"is_not":false,"summary":null,"term":"GO:0004605"}],"single_locus_phenotype":[{"annotations":[114342],"is_not":false,"summary":null,"term":"FYPO:0000356"},{"annotations":[114341],"is_not":false,"summary":null,"term":"FYPO:0006433"},{"annotations":[114344],"is_not":false,"summary":null,"term":"FYPO:0004695"},{"annotations":[114343],"is_not":false,"summary":null,"term":"FYPO:0002227"},{"annotations":[114345],"is_not":false,"summary":null,"term":"FYPO:0001357"}]},"doi":"10.1091/mbc.E14-03-0832","gene_count":1,"genes_by_uniquename":{"SJAG_00426":null},"genotypes_by_uniquename":{"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"bbl1-P363S(aa)","display_uniquename":"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00426:allele-1","expression":"Not assayed or wild type"}]}]}},"ltp_gene_count":1,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2014","pubmed_entrez_date":"2014-10-17","pubmed_publication_date":"15 Dec 2014","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000006":null,"FYECO:0000162":null,"FYPO:0000356":null,"FYPO:0001357":null,"FYPO:0002227":null,"FYPO:0004695":null,"FYPO:0006433":null,"FYPO_EXT:0000001":null,"GO:0004605":null,"GO:0005783":null,"GO:0008654":null,"GO:0016024":null},"title":"Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function.","uniquename":"PMID:25318672"}


id: PMID:33495454
data:
  {"abstract":"The endoplasmic reticulum (ER) network consists of tubules with high membrane curvature in cross-section, generated by the reticulons and REEPs. These proteins have two pairs of trans-membrane (TM) segments, followed by an amphipathic helix (APH), but how they induce curvature is poorly understood. Here, we show that REEPs form homodimers by interaction within the membrane. When overexpressed or reconstituted at high concentrations with phospholipids, REEPs cause extreme curvature through their TMs, generating lipoprotein particles instead of vesicles. The APH facilitates curvature generation, as its mutation prevents ER network formation of reconstituted proteoliposomes, and synthetic L- or D-amino acid peptides abolish ER network formation in Xenopus egg extracts. In Schizosaccharomyces japonicus, the APH is required for reticulon's exclusive ER-tubule localization and restricted mobility. Thus, the TMs and APH cooperate to generate high membrane curvature. We propose that the formation of splayed REEP/reticulon dimers is responsible for ER tubule formation.","alleles_by_uniquename":{"SJAG_01374:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01374","name":"nup132delta","uniquename":"SJAG_01374:allele-1"}},"annotation_curators":[{"annotation_count":8,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":"0000-0002-8138-6851"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-07-09","authors":"Wang N, Clark LD, Gao Y, Kozlov MM, Shemesh T, Rapoport TA","authors_abbrev":"Wang N et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2021-07-09 16:24:24","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-07-09 16:24:24","canto_session_key":"23c6ae79d435aba5","canto_session_submitted_date":"2021-07-09 16:24:16","canto_triage_status":"Curatable","citation":"Nat Commun 2021 01 25;12(1):568","cv_annotations":{"biological_process":[{"annotations":[114391,114397],"is_not":false,"summary":null,"term":"GO:0097753"}],"cellular_component":[{"annotations":[114392,114393],"is_not":false,"summary":null,"term":"GO:0032541"},{"annotations":[114394,114395],"is_not":false,"summary":null,"term":"GO:0005643"}],"single_locus_phenotype":[{"annotations":[114396],"is_not":false,"summary":null,"term":"FYPO:0003973"}]},"doi":"10.1038/s41467-020-20625-y","gene_count":4,"genes_by_uniquename":{"SJAG_01374":null,"SJAG_01834":null,"SJAG_01848":null,"SJAG_03795":null},"genotypes_by_uniquename":{"nup132delta":{"display_name":"nup132delta","display_uniquename":"nup132delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01374:allele-1","expression":"Null"}]}]}},"ltp_gene_count":4,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[{"evidence":"Reconstituted Complex","gene_uniquename":"SJAG_03795","interactor_uniquename":"SJAG_03795","reference_uniquename":"PMID:33495454","throughput":"low"}],"publication_year":"2021","pubmed_entrez_date":"2021-01-26","pubmed_publication_date":"25 01 2021","terms_by_termid":{"FYPO:0003973":null,"GO:0005643":null,"GO:0032541":null,"GO:0097753":null},"title":"Mechanism of membrane-curvature generation by ER-tubule shaping proteins.","uniquename":"PMID:33495454"}


id: GO_REF:0000043
data:
  {"alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"canto_curator_role":"JaponicusDB","cv_annotations":{"biological_process":[{"annotations":[67936],"is_not":false,"summary":null,"term":"GO:0009088"}],"molecular_function":[{"annotations":[66096,66804],"is_not":false,"summary":null,"term":"GO:0003779"},{"annotations":[69817],"is_not":false,"summary":null,"term":"GO:0004812"},{"annotations":[60088],"is_not":false,"summary":null,"term":"GO:0004190"},{"annotations":[57104,57631,64484,66550],"is_not":false,"summary":null,"term":"GO:0005524"},{"annotations":[67520],"is_not":false,"summary":null,"term":"GO:0008061"},{"annotations":[57971,67624],"is_not":false,"summary":null,"term":"GO:0008483"}]},"gene_count":12,"genes_by_uniquename":{"SJAG_00152":null,"SJAG_00521":null,"SJAG_00620":null,"SJAG_00691":null,"SJAG_01595":null,"SJAG_01874":null,"SJAG_01953":null,"SJAG_02263":null,"SJAG_02860":null,"SJAG_03420":null,"SJAG_03692":null,"SJAG_03856":null},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"terms_by_termid":{"GO:0003779":null,"GO:0004190":null,"GO:0004812":null,"GO:0005524":null,"GO:0008061":null,"GO:0008483":null,"GO:0009088":null},"uniquename":"GO_REF:0000043"}


id: PMID:23145069
data:
  {"abstract":"The ERH gene encodes a highly conserved small nuclear protein with a unique amino acid sequence and three-dimensional structure but unknown function. The gene is present in animals, plants, and protists but to date has only been found in few fungi. Here we report that ERH homologs are also present in all four species from the genus Schizosaccharomyces, S. pombe, S. octosporus, S. cryophilus, and S. japonicus, which, however, are an exception in this respect among Ascomycota and Basidiomycota. The ERH protein sequence is moderately conserved within the genus (58% identity between S. pombe and S.japonicus), but the intron-rich genes have almost identical intron-exon organizations in all four species. In S. pombe, erh1(+) is expressed at a roughly constant level during vegetative growth and adaptation to unfavorable conditions such as nutrient limitation and hyperosmotic stress caused by sorbitol. Erh1p localizes preferentially to the nucleus with the exception of the nucleolus, but is also present in the cytoplasm. Cells lacking erh1(+) have an aberrant cell morphology and a comma-like shape when cultured to the stationary phase, and exhibit a delayed recovery from this phase followed by slower growth. Loss of erh1(+) in an auxotrophic background results in enhanced arrest in the G1 phase following nutritional stress, and also leads to hypersensitivity to agents inducing hyperosmotic stress (sorbitol), inhibiting DNA replication (hydroxyurea), and destabilizing the plasma membrane (SDS); this hypersensitivity can be abolished by expression of S. pombe erh1(+) and, to a lesser extent, S. japonicus erh1(+) or human ERH. Erh1p fails to interact with the human Ciz1 and PDIP46/SKAR proteins, known molecular partners of human ERH. Our data suggest that in Schizosaccharomyces sp. erh1(+) is non-essential for normal growth and Erh1p could play a role in response to adverse environmental conditions and in cell cycle regulation.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Krzyzanowski MK, Kozlowska E, Kozlowski P","authors_abbrev":"Krzyzanowski MK et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Sequence feature or region","citation":"PLoS One 2012;7(11):e49059","cv_annotations":{},"doi":"10.1371/journal.pone.0049059","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2012","pubmed_entrez_date":"2012-11-13","pubmed_publication_date":"2012","terms_by_termid":{},"title":"Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe.","uniquename":"PMID:23145069"}


id: PMID:37088673
data:
  {"abstract":"Making wine via spontaneous fermentation without sulfur dioxide and commercial yeast (spontaneous winemaking) is increasing in recent year, but there is scant research regarding microbial communities present in Japan during spontaneous winemaking using culture-independent molecular methods. We analyzed fungal communities and populations during laboratory-scale spontaneous winemaking using sterilized labware to avoid winery-resident microbes. In the spontaneous fermentation of four grape varieties (Pinot Noir, Riesling, Koshu, and Koshusanjaku) grown in the same Japanese vineyard, our analysis of yeast and other fungal species by next-generation sequencing based on the ITS1 region demonstrated that Saccharomyces cerevisiae was eventually dominant in seven of 12 fermentation batches (three replications for each grape variety), whereas non-Saccharomyces species (e.g., Schizosaccharomyces japonicus, Lachancea dasiensis, and Hanseniaspora valbyensis) became dominant in four batches at the end of fermentation. In another batch, lactic acid bacteria (LAB) became dominant and the fermentation remained incomplete. Diverse microbes were involved in the spontaneous fermentation (particularly in Koshusanjaku), indicating that residual sugar remained and lactic and acetic acid largely increased. Compared to the control wine made with SO 2  and commercial yeast, the concentration of lactic acid was 47-fold higher in the must dominated by L. dasiensis, and the concentrations of acetic acid and lactic acid were 10-fold and 20-fold higher in the must dominated by LAB, respectively. Even when indigenous S. cerevisiae became dominant, the finished wines obtained high sensory-analysis scores for complexity but low scores for varietal typicality, indicating the risk of fermentation with unselected wild yeast on the grapes grown in Japan.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Shimizu H, Kamada A, Koyama K, Iwashita K, Goto-Yamamoto N","authors_abbrev":"Shimizu H et al.","canto_added_date":"2023-05-04 00:40:03","canto_curator_role":"JaponicusDB","canto_triage_status":"Cell composition or WT feature","citation":"J Biosci Bioeng 2023 Apr 21;","cv_annotations":{},"doi":"10.1016/j.jbiosc.2023.03.013","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2023","pubmed_entrez_date":"2023-04-23","pubmed_publication_date":"21 Apr 2023","terms_by_termid":{},"title":"Yeast diversity during the spontaneous fermentation of wine with only the microbiota on grapes cultivated in Japan.","uniquename":"PMID:37088673"}


id: PMID:33022982
data:
  {"abstract":"Nowadays commercial preparations of yeast polysaccharides (PSs), in particular mannoproteins, are widely used for wine colloidal and tartrate salt stabilization. In this context, the industry has developed different processes for the isolation and purification of PSs from the cell wall of  Saccharomyces cerevisiae . This yeast releases limited amounts of mannoproteins in the growth medium, thus making their direct isolation from the culture broth not economically feasible. On the contrary,  Schizosaccharomyces japonicus , a non- Saccharomyces  yeast isolated from wine, releases significant amounts of PSs during the alcoholic fermentation. In the present work, PSs released by  Sch. japonicus  were recovered from the growth medium by ultrafiltration and their impact on the wine colloidal stability was evaluated. Interestingly, these PSs contribute positively to the wine protein stability. The visible haziness of the heat-treated wine decreases as the concentration of added PSs increases. SDS-PAGE Gel electrophoresis results of the haze and of the supernatant after the heat stability test are consistent with the turbidity measurements. Moreover, particle size distributions of the heat-treated wines, as obtained by Dynamic Light Scattering (DLS), show a reduction in the average dimension of the protein aggregates as the concentration of added PSs increases.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Millarini V, Ignesti S, Cappelli S, Ferraro G, Adessi A, Zanoni B, Fratini E, Domizio P","authors_abbrev":"Millarini V et al.","canto_added_date":"2021-05-10 08:46:37","canto_curator_role":"JaponicusDB","canto_triage_status":"Biotech","citation":"Foods 2020 Oct 03;9(10)","cv_annotations":{},"doi":"10.3390/foods9101407","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2020","pubmed_entrez_date":"2020-10-07","pubmed_publication_date":"03 Oct 2020","terms_by_termid":{},"title":"Protection of Wine from Protein Haze Using  Schizosaccharomyces japonicus  Polysaccharides.","uniquename":"PMID:33022982"}


id: PMID:32915139
data:
  {"abstract":"Cytokinesis, which enables the physical separation of daughter cells once mitosis has been completed, is executed in fungal and animal cells by a contractile actin- and myosin-based ring (CAR). In the fission yeast  Schizosaccharomyces pombe,  the formin For3 nucleates actin cables and also co-operates for CAR assembly during cytokinesis. Mitogen-activated protein kinases (MAPKs) regulate essential adaptive responses in eukaryotic organisms to environmental changes. We show that the stress-activated protein kinase pathway (SAPK) and its effector, MAPK Sty1, downregulates CAR assembly in  S. pombe  when its integrity becomes compromised during cytoskeletal damage and stress by reducing For3 levels. Accurate control of For3 levels by the SAPK pathway may thus represent a novel regulatory mechanism of cytokinesis outcome in response to environmental cues. Conversely, SAPK signaling favors CAR assembly and integrity in its close relative  Schizosaccharomyces japonicus,  revealing a remarkable evolutionary divergence of this response within the fission yeast clade.","alleles_by_uniquename":{"SJAG_00266:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00266","name":"atf1delta","uniquename":"SJAG_00266:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"}},"annotation_curators":[{"annotation_count":5,"community_curator":true,"file_name":null,"file_type":null,"name":"Elisa Gómez Gil","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-05-13","authors":"Gómez-Gil E, Martín-García R, Vicente-Soler J, Franco A, Vázquez-Marín B, Prieto-Ruiz F, Soto T, Pérez P, Madrid M, Cansado J","authors_abbrev":"Gómez-Gil E et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2023-06-24 05:18:12","canto_curator_name":"Elisa Gómez Gil","canto_curator_role":"community","canto_first_approved_date":"2021-05-13 16:19:42","canto_session_key":"382ba25ae62a1134","canto_session_submitted_date":"2021-05-13 14:28:51","canto_triage_status":"Curatable","citation":"Elife 2020 09 11;9","cv_annotations":{"PSI-MOD":[{"annotations":[114262],"is_not":false,"summary":null,"term":"MOD:00696"}],"biological_process":[{"annotations":[114263],"is_not":false,"summary":null,"term":"GO:1903499"}],"single_locus_phenotype":[{"annotations":[114261],"is_not":false,"summary":null,"term":"FYPO:0002998"},{"annotations":[114259,114260],"is_not":false,"summary":null,"term":"FYPO:0000107"}]},"doi":"10.7554/eLife.57951","gene_count":2,"genes_by_uniquename":{"SJAG_00266":null,"SJAG_02592":null},"genotypes_by_uniquename":{"atf1delta":{"display_name":"atf1delta","display_uniquename":"atf1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00266:allele-1","expression":"Null"}]}]},"sty1delta":{"display_name":"sty1delta","display_uniquename":"sty1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02592:allele-1","expression":"Null"}]}]}},"ltp_gene_count":2,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2020","pubmed_entrez_date":"2020-09-11","pubmed_publication_date":"11 09 2020","terms_by_termid":{"FYECO:0000137":null,"FYECO:0000248":null,"FYPO:0000107":null,"FYPO:0002998":null,"FYPO_EXT:0000001":null,"GO:0120306":null,"GO:1903499":null,"MOD:00696":null},"title":"Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels.","uniquename":"PMID:32915139"}


id: PMID:28655757
data:
  {"abstract":"Cytokinesis in many eukaryotes involves a tension-generating actomyosin-based contractile ring. Many components of actomyosin rings turn over during contraction, although the significance of this turnover has remained enigmatic. Here, using  Schizosaccharomyces japonicus , we investigate the role of turnover of actin and myosin II in its contraction. Actomyosin ring components self-organize into ∼1-µm-spaced clusters instead of undergoing full-ring contraction in the absence of continuous actin polymerization. This effect is reversed when actin filaments are stabilized. We tested the idea that the function of turnover is to ensure actin filament homeostasis in a synthetic system, in which we abolished turnover by fixing rings in cell ghosts with formaldehyde. We found that these rings contracted fully upon exogenous addition of a vertebrate myosin. We conclude that actin turnover is required to maintain actin filament homeostasis during ring contraction and that the requirement for turnover can be bypassed if homeostasis is achieved artificially.","alleles_by_uniquename":{},"annotation_curators":[{"annotation_count":5,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":"0000-0002-8138-6851"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-07-09","authors":"Chew TG, Huang J, Palani S, Sommese R, Kamnev A, Hatano T, Gu Y, Oliferenko S, Sivaramakrishnan S, Balasubramanian MK","authors_abbrev":"Chew TG et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2021-07-09 13:45:34","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-07-09 13:45:34","canto_session_key":"5ead7a365a97d8ab","canto_session_submitted_date":"2021-07-09 13:45:28","canto_triage_status":"Curatable","citation":"J Cell Biol 2017 09 04;216(9):2657-2667","cv_annotations":{"cellular_component":[{"annotations":[114203,114204,114205,114206,114207],"is_not":false,"summary":null,"term":"GO:0005826"}]},"doi":"10.1083/jcb.201701104","gene_count":5,"genes_by_uniquename":{"SJAG_01665":null,"SJAG_02431":null,"SJAG_03596":null,"SJAG_03703":null,"SJAG_04498":null},"genotypes_by_uniquename":{},"ltp_gene_count":5,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2017","pubmed_entrez_date":"2017-06-29","pubmed_publication_date":"04 09 2017","terms_by_termid":{"GO:0005826":null},"title":"Actin turnover maintains actin filament homeostasis during cytokinetic ring contraction.","uniquename":"PMID:28655757"}


id: PMID:35940784
data:
  {"abstract":"Schizosaccharomyces japonicus have been found as dominant yeast species coexisting with Saccharomyces cerevisiae during late stages of spontaneous fermentation of local grapes in Guizhou, China. Therefore, this study further investigated the impacts of the two indigenous yeast species on typicality of crystal grape (Niagara) wine. Five indigenous and one commercial S. cerevisiae strains were firstly selected based on their genotypes and fermentation traits in synthetic medium. All the six S. cerevisiae exhibited high tolerance to glucose, temperature, and SO 2 . The two killer active strains FBKL2.996 and FBKL2.9126 showed relative higher tolerance capacity of ethanol, pH and osmotic pressure than the other four S. cerevisiae strains. Further pure fermentation of six strains using crystal grape must exhibited different contents of volatile compounds, with commercial strain CECA producing the highest levels of acetate esters (phenethyl acetate), ethyl esters (ethyl caprylate, ethyl hexanoate), n-caprylic acid isobutyl ester, and terpenes (linalool) whereas being ranked the last in the sensory analysis. The co-inoculation of indigenous S. japonicus with each of the six S. cerevisiae strains increased the acetate esters (mainly isoamyl acetate) by 2-3 times in crystal grape wine. The indigenous S. cerevisiae FBKL2.9128 showed the most obvious variation of volatile compounds between pure and mixed fermentation, exhibiting the significant increase of isoamyl acetate, ethyl decanoate, ethyl caprylate, ethyl hexanoate, methyl decanoate, and dodecanal when co-inoculated with S. japonicus. Sugar addition in immature crystal grape juice increased the ethanol, glycerol, and some volatile compounds such as ethyl butyrate, but decreased the volatile compounds with floral and animal odors. The aroma sensory analysis confirmed the decrease of varietal aroma in wines with sugar addition when comparing with wines made from immature crystal grape. The results of this study provide basic information on the impact of indigenous S. cerevisaie and S. japonicus, and sugar addition on typicality of crystal grape wine, which would help to improve the wine flavor made from crystal grape in southwest China.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Wang C, Liang S, Yang J, Wu C, Qiu S","authors_abbrev":"Wang C et al.","canto_added_date":"2023-05-04 00:40:03","canto_curator_role":"JaponicusDB","canto_triage_status":"Cell composition or WT feature","citation":"Food Res Int 2022 Sep;159:111580","cv_annotations":{},"doi":"10.1016/j.foodres.2022.111580","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2022","pubmed_entrez_date":"2022-08-08","pubmed_publication_date":"Sep 2022","terms_by_termid":{},"title":"The impact of indigenous Saccharomyces cerevisiae and Schizosaccharomyces japonicus on typicality of crystal grape (Niagara) wine.","uniquename":"PMID:35940784"}


id: PMID:22300943
data:
  {"abstract":"The fission yeasts (Schizosaccharomyces) representing a highly divergent phylogenetic branch of Fungi evolved from filamentous ancestors by gradual transition from mycelial growth to yeast morphology. For the transition, a mechanism had been developed that separates the sister cells after the completion of cytokinesis. Numerous components of the separation mechanism have been characterised in Schizosaccharomycespombe, including the zinc-finger transcription factor Ace2p and the fork-head transcription factor Sep1p. Here we show that both regulators have regions conserved within the genus. The most conserved parts contain the DNA-binding domains whose amino-acid sequences perfectly reflect the phylogenetic positions of the species. The less conserved parts of the proteins contain sequence blocks specific for the whole genus or only for the species propagating predominantly or exclusively as yeasts. Inactivation of either gene in the dimorphic species Schizosaccharomycesjaponicus abolished cell separation in the yeast phase conferring hypha-like morphology but did not change the growth pattern to unipolar and did not cause extensive polar vacuolation characteristic of the true mycelium. Neither mutation affected the mycelial phase, but both mutations hampered the hyphal fragmentation at the mycelium-to-yeast transition. Ace2p(Sj) acts downstream of Sep1p(Sj) and regulates the orthologues of the Ace2p-dependent S.pombe genes agn1(+) (1,3-alpha-glucanase) and eng1(+) (1,3-beta-glucanase) but does not regulate the orthologue of cfh4(+) (chitin synthase regulatory factor). These results and the complementation of the cell separation defects of the ace2(-) and sep1(-) mutations of S.pombe by heterologously expressed ace2(Sj) and sep1(Sj) indicate that the cell separation mechanism is conserved in the Schizosaccharomyces genus.","alleles_by_uniquename":{"SJAG_02252:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02252","name":"ace2delta","uniquename":"SJAG_02252:allele-1"},"SJAG_03143:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03143","name":"sep1delta","uniquename":"SJAG_03143:allele-1"}},"annotation_curators":[{"annotation_count":7,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2022-12-09","authors":"Balazs A, Batta G, Miklos I, Acs-Szabo L, Vazquez de Aldana CR, Sipiczki M","authors_abbrev":"Balazs A et al.","canto_added_date":"2022-12-09 17:19:01","canto_annotation_status":"APPROVED","canto_approved_date":"2022-12-09 17:39:12","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2022-12-09 17:39:12","canto_session_key":"f106e12e6366fbad","canto_session_submitted_date":"2022-12-09 17:38:34","canto_triage_status":"Curatable","citation":"Fungal Genet Biol 2012 Mar;49(3):235-49","cv_annotations":{"single_locus_phenotype":[{"annotations":[114368,114369],"is_not":false,"summary":null,"term":"FYPO:0006557"}]},"doi":"10.1016/j.fgb.2012.01.003","gene_count":2,"genes_by_uniquename":{"SJAG_02252":null,"SJAG_03143":null},"genotypes_by_uniquename":{"ace2delta":{"display_name":"ace2delta","display_uniquename":"ace2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02252:allele-1","expression":"Null"}]}]},"sep1delta":{"display_name":"sep1delta","display_uniquename":"sep1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03143:allele-1","expression":"Null"}]}]}},"ltp_gene_count":2,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2012","pubmed_entrez_date":"2012-02-04","pubmed_publication_date":"Mar 2012","terms_by_termid":{"FYECO:0000137":null,"FYPO:0006557":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null},"title":"Conserved regulators of the cell separation process in Schizosaccharomyces.","uniquename":"PMID:22300943"}


id: PMID:26263485
data:
  {"abstract":"Cytokinesis must be regulated in time and space in order to preserve genome integrity during cell proliferation and to allow daughter cells to adopt distinct fates and geometries during differentiation. The fission yeast Schizosaccharomyces pombe has been a popular model organism for understanding spatiotemporal regulation of cytokinesis in a symmetrically dividing cell. Recent work on another member of the same genus, Schisozaccharomyces japonicus, suggests that S. pombe may have evolved an unusual division site placement mechanism based on a recently duplicated anillin paralog. Here we discuss an extraordinary evolutionary plasticity of cytokinesis within the fission yeast clade and argue that the comparative cell biology approach may provide functional insights beyond those afforded by scrutinizing individual model species.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Gu Y, Oliferenko S","authors_abbrev":"Gu Y et al.","canto_added_date":"2023-05-04 00:40:04","canto_curator_role":"JaponicusDB","canto_triage_status":"Review or comment","citation":"Curr Opin Microbiol 2015 Dec;28:18-25","cv_annotations":{},"doi":"10.1016/j.mib.2015.07.011","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2015","pubmed_entrez_date":"2015-08-12","pubmed_publication_date":"Dec 2015","terms_by_termid":{},"title":"Comparative biology of cell division in the fission yeast clade.","uniquename":"PMID:26263485"}


id: PMID:28954740
data:
  {"abstract":"After mitosis, nuclear reorganization occurs together with decondensation of mitotic chromosomes and reformation of the nuclear envelope, thereby restoring the Ran-GTP gradient between the nucleus and cytoplasm. The Ran-GTP gradient is dependent on Pim1/RCC1. Interestingly, a defect in Pim1/RCC1 in  Schizosaccharomyces pombe  causes postmitotic condensation of chromatin, namely hypercondensation, suggesting a relationship between the Ran-GTP gradient and chromosome decondensation. However, how Ran-GTP interacts with chromosome decondensation is unresolved. To examine this interaction, we used  Schizosaccharomyces japonicus , which is known to undergo partial breakdown of the nuclear membrane during mitosis. We found that Pim1/RCC1 was localized on nuclear pores, but this localization failed in a temperature-sensitive mutant of Pim1/RCC1. The mutant cells exhibited hypercondensed chromatin after mitosis due to prolonged association of condensin on the chromosomes. Conceivably, a condensin-dephosphorylation defect might cause hypercondensed chromatin, since chromosomal localization of condensin is dependent on phosphorylation by cyclin-dependent kinase (CDK). Indeed, CDK-phospho-mimic mutation of condensin alone caused untimely condensin localization, resulting in hypercondensed chromatin. Together, these results suggest that dephosphorylation of CDK sites of condensin might require the Ran-GTP gradient produced by nuclear pore-localized Pim1/RCC1.","alleles_by_uniquename":{"SJAG_00871:allele-1":{"allele_type":"amino_acid_mutation","description":"cut3-T19E","gene_uniquename":"SJAG_00871","name":"cut3-T19E","uniquename":"SJAG_00871:allele-1"},"SJAG_04284:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04284","name":"nup61delta","uniquename":"SJAG_04284:allele-1"},"SJAG_04464:allele-1":{"allele_type":"amino_acid_mutation","description":"R152C","gene_uniquename":"SJAG_04464","name":"pim1-R152C","synonyms":[{"name":"Inferred CDK-phospho-mimic mutation","reference":"PMID:28954740","type":"exact"}],"uniquename":"SJAG_04464:allele-1"}},"annotation_curators":[{"annotation_count":12,"community_curator":true,"file_name":null,"file_type":null,"name":"Sho Okamoto","orcid":null}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2022-11-23","authors":"Aoki K, Niki H","authors_abbrev":"Aoki K et al.","canto_added_date":"2021-05-10 08:46:37","canto_annotation_status":"APPROVED","canto_approved_date":"2022-11-23 15:00:26","canto_curator_name":"Sho Okamoto","canto_curator_role":"community","canto_first_approved_date":"2022-11-23 15:00:26","canto_session_key":"7c26b8235c98c3eb","canto_session_submitted_date":"2022-11-23 15:00:18","canto_triage_status":"Curatable","citation":"Biol Open 2017 Nov 15;6(11):1614-1628","cv_annotations":{"biological_process":[{"annotations":[114433],"is_not":false,"summary":null,"term":"GO:0101024"},{"annotations":[114438],"is_not":false,"summary":null,"term":"GO:0006998"}],"cellular_component":[{"annotations":[114437],"is_not":false,"summary":null,"term":"GO:0120321"}],"multi_locus_phenotype":[{"annotations":[114440],"is_not":false,"summary":null,"term":"FYPO:0000619"},{"annotations":[114439],"is_not":false,"summary":null,"term":"FYPO:0001489"}],"single_locus_phenotype":[{"annotations":[114441],"is_not":false,"summary":null,"term":"FYPO:0000619"},{"annotations":[114435],"is_not":false,"summary":null,"term":"FYPO:0003738"},{"annotations":[114442],"is_not":false,"summary":null,"term":"FYPO:0000815"},{"annotations":[114434],"is_not":false,"summary":null,"term":"FYPO:0000082"},{"annotations":[114436],"is_not":false,"summary":null,"term":"FYPO:0003976"},{"annotations":[114432],"is_not":false,"summary":null,"term":"FYPO:0001387"}]},"doi":"10.1242/bio.027193","gene_count":4,"genes_by_uniquename":{"SJAG_00471":null,"SJAG_00871":null,"SJAG_04284":null,"SJAG_04464":null},"genotypes_by_uniquename":{"cut3-T19E-cut3-T19E-amino_acid_mutation-expression-not_assayed_or_wild_type__pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"cut3-T19E(aa) pim1-R152C(aa)","display_uniquename":"cut3-T19E-cut3-T19E-amino_acid_mutation-expression-not_assayed_or_wild_type__pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00871:allele-1","expression":"Not assayed or wild type"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_04464:allele-1","expression":"Not assayed or wild type"}]}]},"nup61delta":{"display_name":"nup61delta","display_uniquename":"nup61delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04284:allele-1","expression":"Null"}]}]},"pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"pim1-R152C(aa)","display_uniquename":"pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04464:allele-1","expression":"Not assayed or wild type"}]}]}},"ltp_gene_count":4,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[{"evidence":"Affinity Capture-Western","gene_uniquename":"SJAG_04464","interactor_uniquename":"SJAG_00471","reference_uniquename":"PMID:28954740","throughput":"low"}],"publication_year":"2017","pubmed_entrez_date":"2017-09-29","pubmed_publication_date":"15 Nov 2017","references_by_uniquename":{"PMID:28954740":null},"terms_by_termid":{"FYECO:0000004":null,"FYECO:0000005":null,"FYECO:0000137":null,"FYPO:0000082":null,"FYPO:0000619":null,"FYPO:0000815":null,"FYPO:0001387":null,"FYPO:0001489":null,"FYPO:0003738":null,"FYPO:0003976":null,"FYPO_EXT:0000001":null,"GO:0006998":null,"GO:0101024":null,"GO:0120321":null},"title":"Release of condensin from mitotic chromosomes requires the Ran-GTP gradient in the reorganized nucleus.","uniquename":"PMID:28954740"}


id: PMID:31956022
data:
  {"abstract":"Membrane function is fundamental to life. Each species explores membrane lipid diversity within a genetically predefined range of possibilities. How membrane lipid composition in turn defines the functional space available for evolution of membrane-centered processes remains largely unknown. We address this fundamental question using related fission yeasts Schizosaccharomyces pombe and Schizosaccharomyces japonicus. We show that, unlike S. pombe that generates membranes where both glycerophospholipid acyl tails are predominantly 16-18 carbons long, S. japonicus synthesizes unusual \"asymmetrical\" glycerophospholipids where the tails differ in length by 6-8 carbons. This results in stiffer bilayers with distinct lipid packing properties. Retroengineered S. pombe synthesizing the S.-japonicus-type phospholipids exhibits unfolded protein response and downregulates secretion. Importantly, our protein sequence comparisons and domain swap experiments support the hypothesis that transmembrane helices co-evolve with membranes, suggesting that, on the evolutionary scale, changes in membrane lipid composition may necessitate extensive adaptation of the membrane-associated proteome.","alleles_by_uniquename":{"SJAG_01458:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01458","name":"acb1delta","uniquename":"SJAG_01458:allele-1"}},"annotation_curators":[{"annotation_count":4,"community_curator":false,"file_name":null,"file_type":null,"name":"Snezhana Oliferenko","orcid":"0000-0002-8138-6851"}],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-07-09","authors":"Makarova M, Peter M, Balogh G, Glatz A, MacRae JI, Lopez Mora N, Booth P, Makeyev E, Vigh L, Oliferenko S","authors_abbrev":"Makarova M et al.","canto_added_date":"2021-05-10 02:37:19","canto_annotation_status":"APPROVED","canto_approved_date":"2021-07-09 13:38:09","canto_curator_name":"Snezhana Oliferenko","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-07-09 13:38:09","canto_session_key":"801e82954edbb6c1","canto_session_submitted_date":"2021-07-09 13:38:00","canto_triage_status":"Curatable","citation":"Curr Biol 2020 02 03;30(3):367-380.e8","cv_annotations":{"cellular_component":[{"annotations":[114609],"is_not":false,"summary":null,"term":"GO:0005801"},{"annotations":[114611],"is_not":false,"summary":null,"term":"GO:0005829"}],"single_locus_phenotype":[{"annotations":[114610],"is_not":false,"summary":null,"term":"FYPO:0000719"}]},"doi":"10.1016/j.cub.2019.11.043","gene_count":4,"genes_by_uniquename":{"SJAG_00816":null,"SJAG_01458":null,"SJAG_04107":null,"SJAG_04972":null},"genotypes_by_uniquename":{"acb1delta":{"display_name":"acb1delta","display_uniquename":"acb1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01458:allele-1","expression":"Null"}]}]}},"ltp_gene_count":4,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[{"evidence":"Co-purification","gene_uniquename":"SJAG_04972","interactor_uniquename":"SJAG_04107","reference_uniquename":"PMID:31956022","throughput":"low"}],"publication_year":"2020","pubmed_entrez_date":"2020-01-21","pubmed_publication_date":"03 02 2020","terms_by_termid":{"FYECO:0000126":null,"FYPO:0000719":null,"GO:0005801":null,"GO:0005829":null},"title":"Delineating the Rules for Structural Adaptation of Membrane-Associated Proteins to Evolutionary Changes in Membrane Lipidome.","uniquename":"PMID:31956022"}


id: PMID:2021084
data:
  {"abstract":"The genus Schizosaccharomyces comprises a small, somewhat heterogeneous group of yeast species which have in common a unique mode of vegetative reproduction by cross-wall formation without constriction as well as a certain degree of osmophilia, most strains having been isolated from habitats of high sugar concentration. This study evaluated inter- and intraspecific relationships utilizing nDNA/nDNA optical reassociation and by the analysis of physiological profiles of several strains of each species. Results demonstrate that the genus should be divided into three species: Schiz. japonicus, Schiz. octosporus and Schiz. pombe.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Vaughan Martini A","authors_abbrev":"Vaughan Martini A","canto_added_date":"2023-05-04 00:40:04","canto_curator_role":"JaponicusDB","canto_triage_status":"Cell composition or WT feature","citation":"Yeast 1991 Jan;7(1):73-8","cv_annotations":{},"gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"1991","pubmed_entrez_date":"1991-01-01","pubmed_publication_date":"Jan 1991","terms_by_termid":{},"title":"Evaluation of phylogenetic relationships among fission yeast by nDNA/nDNA reassociation and conventional taxonomic criteria.","uniquename":"PMID:2021084"}


id: PMID:9611807
data:
  {"abstract":"The fission yeast Schizosaccharomyces pombe shows bipolar growth and is a convenient model for studying cell polarity and polar growth. This paper shows that the related Schiz. japonicus var. japonicus can switch to unipolar growth and can exist in both yeast and mycelial phases. On solid media, the yeast phase is unstable and prone to switch to the mycelial form, which shows unipolar growth by tip elongation. The hyphae can colonize the body of the substrate (true mycelium) or just its surface (pseudo-mycelium). The yeast-to-mycelium transition and the growth of the mycelium are regulated by a nutritional gradient and are associated with extensive vacuolation. The mycelium can convert into arthroconidia or return to the yeast phase in response to environmental changes. These environmentally controlled morphological transitions make Schiz. japonicus var. japonicus an attractive model for the investigation of cell polarity and morphogenesis.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"approved_date":"2021-10-07","authors":"Sipiczki M, Takeo K, Yamaguchi M, Yoshida S, Miklos I","authors_abbrev":"Sipiczki M et al.","canto_added_date":"2021-09-30 08:50:02","canto_annotation_status":"APPROVED","canto_approved_date":"2021-10-07 12:30:26","canto_curator_role":"JaponicusDB","canto_first_approved_date":"2021-10-07 12:30:26","canto_session_key":"fced61f1377cd206","canto_session_submitted_date":"2021-09-30 08:52:46","canto_triage_status":"Curatable","citation":"Microbiology (Reading) 1998 May;144 ( Pt 5):1319-1330","cv_annotations":{},"doi":"10.1099/00221287-144-5-1319","gene_count":0,"genes_by_uniquename":{},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"1998","pubmed_entrez_date":"1998-06-05","pubmed_publication_date":"May 1998","terms_by_termid":{},"title":"Environmentally controlled dimorphic cycle in a fission yeast.","uniquename":"PMID:9611807"}


id: PMID:21873635
data:
  {"abstract":"The goal of the Gene Ontology (GO) project is to provide a uniform way to describe the functions of gene products from organisms across all kingdoms of life and thereby enable analysis of genomic data. Protein annotations are either based on experiments or predicted from protein sequences. Since most sequences have not been experimentally characterized, most available annotations need to be based on predictions. To make as accurate inferences as possible, the GO Consortium's Reference Genome Project is using an explicit evolutionary framework to infer annotations of proteins from a broad set of genomes from experimental annotations in a semi-automated manner. Most components in the pipeline, such as selection of sequences, building multiple sequence alignments and phylogenetic trees, retrieving experimental annotations and depositing inferred annotations, are fully automated. However, the most crucial step in our pipeline relies on software-assisted curation by an expert biologist. This curation tool, Phylogenetic Annotation and INference Tool (PAINT) helps curators to infer annotations among members of a protein family. PAINT allows curators to make precise assertions as to when functions were gained and lost during evolution and record the evidence (e.g. experimentally supported GO annotations and phylogenetic information including orthology) for those assertions. In this article, we describe how we use PAINT to infer protein function in a phylogenetic context with emphasis on its strengths, limitations and guidelines. We also discuss specific examples showing how PAINT annotations compare with those generated by other highly used homology-based methods.","alleles_by_uniquename":{},"annotation_curators":[],"annotation_details":{},"annotation_file_curators":[],"authors":"Gaudet P, Livstone MS, Lewis SE, Thomas PD","authors_abbrev":"Gaudet P et al.","canto_curator_role":"JaponicusDB","citation":"Brief Bioinform 2011 Sep;12(5):449-62","cv_annotations":{"biological_process":[{"annotations":[76096,77613],"is_not":false,"summary":null,"term":"GO:0044208"},{"annotations":[78590],"is_not":false,"summary":null,"term":"GO:0051083"},{"annotations":[70143,71574,76138],"is_not":false,"summary":null,"term":"GO:0006189"},{"annotations":[77480],"is_not":false,"summary":null,"term":"GO:0006458"},{"annotations":[70305,71335,71691,71833,73123,73604],"is_not":false,"summary":null,"term":"GO:0006207"},{"annotations":[74598,75910],"is_not":false,"summary":null,"term":"GO:0006078"},{"annotations":[71883],"is_not":false,"summary":null,"term":"GO:0009265"},{"annotations":[77428,77723],"is_not":false,"summary":null,"term":"GO:0070935"},{"annotations":[72744],"is_not":false,"summary":null,"term":"GO:0006666"},{"annotations":[78259],"is_not":false,"summary":null,"term":"GO:0051072"},{"annotations":[72400,73517],"is_not":false,"summary":null,"term":"GO:0006015"},{"annotations":[73476],"is_not":false,"summary":null,"term":"GO:0042791"},{"annotations":[74303],"is_not":false,"summary":null,"term":"GO:0036261"},{"annotations":[74766,78194],"is_not":false,"summary":null,"term":"GO:0006370"},{"annotations":[77087],"is_not":false,"summary":null,"term":"GO:0044571"},{"annotations":[72454,73158,74162,77822],"is_not":false,"summary":null,"term":"GO:0006086"},{"annotations":[78717],"is_not":false,"summary":null,"term":"GO:0006084"},{"annotations":[72955,73237,74665,76299,77966,78634],"is_not":false,"summary":null,"term":"GO:0000147"},{"annotations":[74662,75544,78023],"is_not":false,"summary":null,"term":"GO:0051666"},{"annotations":[75951],"is_not":false,"summary":null,"term":"GO:0030036"},{"annotations":[71585,75543,76247],"is_not":false,"summary":null,"term":"GO:0051017"},{"annotations":[74028],"is_not":false,"summary":null,"term":"GO:0071846"},{"annotations":[70270],"is_not":false,"summary":null,"term":"GO:0030042"},{"annotations":[71586],"is_not":false,"summary":null,"term":"GO:0051639"},{"annotations":[78573],"is_not":false,"summary":null,"term":"GO:0031032"},{"annotations":[77179],"is_not":false,"summary":null,"term":"GO:0046464"},{"annotations":[70853],"is_not":false,"summary":null,"term":"GO:0046084"},{"annotations":[73577],"is_not":false,"summary":null,"term":"GO:0006168"},{"annotations":[77871],"is_not":false,"summary":null,"term":"GO:1901911"},{"annotations":[74137],"is_not":false,"summary":null,"term":"GO:0015866"},{"annotations":[76550],"is_not":false,"summary":null,"term":"GO:0006066"},{"annotations":[74689],"is_not":false,"summary":null,"term":"GO:0000256"},{"annotations":[71620],"is_not":false,"summary":null,"term":"GO:0015742"},{"annotations":[76009],"is_not":false,"summary":null,"term":"GO:0032974"},{"annotations":[73035,74770,74895,75443,75912,75933,76659,76675,77494,78519,78730,78883],"is_not":false,"summary":null,"term":"GO:0003333"},{"annotations":[72060],"is_not":false,"summary":null,"term":"GO:0019676"},{"annotations":[70258,74781],"is_not":false,"summary":null,"term":"GO:0072488"},{"annotations":[75635],"is_not":false,"summary":null,"term":"GO:0046033"},{"annotations":[73578],"is_not":false,"summary":null,"term":"GO:0044209"},{"annotations":[70335,72833,75726,76691,77762,77838,78557,78821],"is_not":false,"summary":null,"term":"GO:0031145"},{"annotations":[70541,70846],"is_not":false,"summary":null,"term":"GO:0006526"},{"annotations":[70577,77346],"is_not":false,"summary":null,"term":"GO:0042450"},{"annotations":[77263],"is_not":false,"summary":null,"term":"GO:0019544"},{"annotations":[70669],"is_not":false,"summary":null,"term":"GO:0019547"},{"annotations":[77265],"is_not":false,"summary":null,"term":"GO:0010121"},{"annotations":[70848],"is_not":false,"summary":null,"term":"GO:0000053"},{"annotations":[72457,75885,77039],"is_not":false,"summary":null,"term":"GO:0009073"},{"annotations":[75752],"is_not":false,"summary":null,"term":"GO:0009074"},{"annotations":[71284,71738,73529],"is_not":false,"summary":null,"term":"GO:0000949"},{"annotations":[74312,75677,76780,77158,77684,78371,78499],"is_not":false,"summary":null,"term":"GO:0034314"},{"annotations":[72204],"is_not":false,"summary":null,"term":"GO:0006528"},{"annotations":[76590],"is_not":false,"summary":null,"term":"GO:0006532"},{"annotations":[71158],"is_not":false,"summary":null,"term":"GO:0006533"},{"annotations":[75984],"is_not":false,"summary":null,"term":"GO:0006422"},{"annotations":[78187],"is_not":false,"summary":null,"term":"GO:1902626"},{"annotations":[75689],"is_not":false,"summary":null,"term":"GO:0060172"},{"annotations":[74171],"is_not":false,"summary":null,"term":"GO:0061509"},{"annotations":[71097,74089,74099],"is_not":false,"summary":null,"term":"GO:0016255"},{"annotations":[72082,72678,75164],"is_not":false,"summary":null,"term":"GO:0051315"},{"annotations":[71026,71399,71993,72168,72571,72909,75806,77305,77531,78161,78350],"is_not":false,"summary":null,"term":"GO:0000045"},{"annotations":[74877],"is_not":false,"summary":null,"term":"GO:0097352"},{"annotations":[74372,78301],"is_not":false,"summary":null,"term":"GO:0006914"},{"annotations":[75039,77986,78678],"is_not":false,"summary":null,"term":"GO:0051016"},{"annotations":[70216,72966,78506],"is_not":false,"summary":null,"term":"GO:0006284"},{"annotations":[73920,75864],"is_not":false,"summary":null,"term":"GO:0006285"},{"annotations":[77148],"is_not":false,"summary":null,"term":"GO:0097510"},{"annotations":[73688,74593],"is_not":false,"summary":null,"term":"GO:0006287"},{"annotations":[75379,78048],"is_not":false,"summary":null,"term":"GO:0009102"},{"annotations":[73085],"is_not":false,"summary":null,"term":"GO:0000494"},{"annotations":[78306],"is_not":false,"summary":null,"term":"GO:0000492"},{"annotations":[78830],"is_not":false,"summary":null,"term":"GO:0000495"},{"annotations":[75810,78790],"is_not":false,"summary":null,"term":"GO:0000493"},{"annotations":[70250,74320],"is_not":false,"summary":null,"term":"GO:0071586"},{"annotations":[72823,78265],"is_not":false,"summary":null,"term":"GO:0097720"},{"annotations":[73884],"is_not":false,"summary":null,"term":"GO:0098703"},{"annotations":[72359,73284,77267],"is_not":false,"summary":null,"term":"GO:0070588"},{"annotations":[76814],"is_not":false,"summary":null,"term":"GO:0061621"},{"annotations":[70973],"is_not":false,"summary":null,"term":"GO:0035965"},{"annotations":[71405,78674],"is_not":false,"summary":null,"term":"GO:0032049"},{"annotations":[78863],"is_not":false,"summary":null,"term":"GO:0046705"},{"annotations":[78671],"is_not":false,"summary":null,"term":"GO:0016024"},{"annotations":[70423,73023,75127,77843,78196,78236,78290],"is_not":false,"summary":null,"term":"GO:0045454"},{"annotations":[73778],"is_not":false,"summary":null,"term":"GO:0006038"},{"annotations":[71910,74121,74318,76109,76408,76964,78058,78894],"is_not":false,"summary":null,"term":"GO:0000032"},{"annotations":[70918],"is_not":false,"summary":null,"term":"GO:0098849"},{"annotations":[77785],"is_not":false,"summary":null,"term":"GO:0070370"},{"annotations":[70989,76059],"is_not":false,"summary":null,"term":"GO:0044255"},{"annotations":[71657,75201],"is_not":false,"summary":null,"term":"GO:0034198"},{"annotations":[76582],"is_not":false,"summary":null,"term":"GO:0071244"},{"annotations":[75266,75367],"is_not":false,"summary":null,"term":"GO:0042149"},{"annotations":[71223],"is_not":false,"summary":null,"term":"GO:0071218"},{"annotations":[70427,73074,73116,74378,74511,75930,76584,77846],"is_not":false,"summary":null,"term":"GO:0034599"},{"annotations":[71935],"is_not":false,"summary":null,"term":"GO:0016036"},{"annotations":[76158,77214],"is_not":false,"summary":null,"term":"GO:0009267"},{"annotations":[70309,71358,78438],"is_not":false,"summary":null,"term":"GO:0034080"},{"annotations":[73951,75970,76953,77649,77840],"is_not":false,"summary":null,"term":"GO:0046513"},{"annotations":[75600,75703,77112],"is_not":false,"summary":null,"term":"GO:0051131"},{"annotations":[71286],"is_not":false,"summary":null,"term":"GO:0019988"},{"annotations":[70537],"is_not":false,"summary":null,"term":"GO:1902476"},{"annotations":[70465,70624],"is_not":false,"summary":null,"term":"GO:0006338"},{"annotations":[70310,73275],"is_not":false,"summary":null,"term":"GO:0007059"},{"annotations":[71332,71830,77347],"is_not":false,"summary":null,"term":"GO:0019240"},{"annotations":[78387],"is_not":false,"summary":null,"term":"GO:0072318"},{"annotations":[73404,73822,77187,78388],"is_not":false,"summary":null,"term":"GO:0072583"},{"annotations":[71475],"is_not":false,"summary":null,"term":"GO:0000448"},{"annotations":[71304,71571,77396,78808],"is_not":false,"summary":null,"term":"GO:0015937"},{"annotations":[77089],"is_not":false,"summary":null,"term":"GO:0015938"},{"annotations":[71406],"is_not":false,"summary":null,"term":"GO:0048205"},{"annotations":[72892],"is_not":false,"summary":null,"term":"GO:0090114"},{"annotations":[71521,74177,74530,74909,75484,75871,77303],"is_not":false,"summary":null,"term":"GO:0090110"},{"annotations":[77475],"is_not":false,"summary":null,"term":"GO:0015677"},{"annotations":[74535,77432],"is_not":false,"summary":null,"term":"GO:0042407"},{"annotations":[74493,76510],"is_not":false,"summary":null,"term":"GO:0071034"},{"annotations":[78774],"is_not":false,"summary":null,"term":"GO:0061504"},{"annotations":[72491,75361,76545],"is_not":false,"summary":null,"term":"GO:0006535"},{"annotations":[72322],"is_not":false,"summary":null,"term":"GO:0006423"},{"annotations":[70147],"is_not":false,"summary":null,"term":"GO:0009972"},{"annotations":[78614],"is_not":false,"summary":null,"term":"GO:0031122"},{"annotations":[70489,70505,71154,71927,72183,72286,72947,73059,73229,73289,74182,74675,75328,75564,75794,75920,76227,76445,76615,76878,77162,77165,77178,77182,78418,78700],"is_not":false,"summary":null,"term":"GO:0002181"},{"annotations":[73561],"is_not":false,"summary":null,"term":"GO:0002183"},{"annotations":[73464],"is_not":false,"summary":null,"term":"GO:0002184"},{"annotations":[74206,74337,75180],"is_not":false,"summary":null,"term":"GO:0061640"},{"annotations":[78857],"is_not":false,"summary":null,"term":"GO:0019478"},{"annotations":[78559,78843],"is_not":false,"summary":null,"term":"GO:0046177"},{"annotations":[74071],"is_not":false,"summary":null,"term":"GO:0006014"},{"annotations":[77663],"is_not":false,"summary":null,"term":"GO:0036088"},{"annotations":[73940,75035,76593,78336],"is_not":false,"summary":null,"term":"GO:0000290"},{"annotations":[75207,77730],"is_not":false,"summary":null,"term":"GO:0031087"},{"annotations":[75148],"is_not":false,"summary":null,"term":"GO:0009159"},{"annotations":[70919],"is_not":false,"summary":null,"term":"GO:0010273"},{"annotations":[77870],"is_not":false,"summary":null,"term":"GO:1901909"},{"annotations":[77869],"is_not":false,"summary":null,"term":"GO:1901907"},{"annotations":[71137],"is_not":false,"summary":null,"term":"GO:0046452"},{"annotations":[71823],"is_not":false,"summary":null,"term":"GO:0140206"},{"annotations":[77866],"is_not":false,"summary":null,"term":"GO:0071543"},{"annotations":[70566,72493,73553,73569,77961],"is_not":false,"summary":null,"term":"GO:0006974"},{"annotations":[75597,78034],"is_not":false,"summary":null,"term":"GO:1990683"},{"annotations":[72231,74588,74983],"is_not":false,"summary":null,"term":"GO:0000730"},{"annotations":[71247,71483,71733,72216,72759,73469,76395,77152],"is_not":false,"summary":null,"term":"GO:0006281"},{"annotations":[73686,74591],"is_not":false,"summary":null,"term":"GO:0045004"},{"annotations":[75210,78837],"is_not":false,"summary":null,"term":"GO:0043137"},{"annotations":[74067,78439],"is_not":false,"summary":null,"term":"GO:0006335"},{"annotations":[70575],"is_not":false,"summary":null,"term":"GO:1902983"},{"annotations":[72230],"is_not":false,"summary":null,"term":"GO:0042148"},{"annotations":[76001],"is_not":false,"summary":null,"term":"GO:1904161"},{"annotations":[70655],"is_not":false,"summary":null,"term":"GO:0006265"},{"annotations":[71948,74005],"is_not":false,"summary":null,"term":"GO:0019408"},{"annotations":[71327,74459],"is_not":false,"summary":null,"term":"GO:0006488"},{"annotations":[78636],"is_not":false,"summary":null,"term":"GO:0043048"},{"annotations":[75598,77918,78035],"is_not":false,"summary":null,"term":"GO:0006302"},{"annotations":[71896,73897,74159,78567,78799],"is_not":false,"summary":null,"term":"GO:0000727"},{"annotations":[70314,70675,70983,72373,73833,74396,74685,76163,76533,76557,76673,77285,77740,78053,78072,78103],"is_not":false,"summary":null,"term":"GO:0000724"},{"annotations":[75657,76212],"is_not":false,"summary":null,"term":"GO:0045002"},{"annotations":[70954,76986],"is_not":false,"summary":null,"term":"GO:0045003"},{"annotations":[70963],"is_not":false,"summary":null,"term":"GO:0006233"},{"annotations":[78331],"is_not":false,"summary":null,"term":"GO:0006231"},{"annotations":[70964],"is_not":false,"summary":null,"term":"GO:0006235"},{"annotations":[70962],"is_not":false,"summary":null,"term":"GO:0006227"},{"annotations":[78002],"is_not":false,"summary":null,"term":"GO:0006226"},{"annotations":[78000],"is_not":false,"summary":null,"term":"GO:0046081"},{"annotations":[71510],"is_not":false,"summary":null,"term":"GO:0034498"},{"annotations":[74227],"is_not":false,"summary":null,"term":"GO:0045022"},{"annotations":[70122,70600,71608,76329],"is_not":false,"summary":null,"term":"GO:0070941"},{"annotations":[72740,74349,78242,78357],"is_not":false,"summary":null,"term":"GO:0032456"},{"annotations":[70124,70533,71398,71461,71610,71817,72108,73096,73460,74664,74888,75247,76331,78025,78207,78368,78490,78633],"is_not":false,"summary":null,"term":"GO:0006897"},{"annotations":[70597,72781,76907],"is_not":false,"summary":null,"term":"GO:0000480"},{"annotations":[70595,71275,71923,72779,74096],"is_not":false,"summary":null,"term":"GO:0000447"},{"annotations":[73856,75124,75926],"is_not":false,"summary":null,"term":"GO:0000479"},{"annotations":[74097],"is_not":false,"summary":null,"term":"GO:0000461"},{"annotations":[70596,72780,76906],"is_not":false,"summary":null,"term":"GO:0000472"},{"annotations":[77273],"is_not":false,"summary":null,"term":"GO:0016320"},{"annotations":[71887],"is_not":false,"summary":null,"term":"GO:0090158"},{"annotations":[70171,70648,71065,71215,71473,72011,72273,72541,72599,73252,73538,73835,74001,74217,74325,74427,74464,74815,74923,76065,76175,76630,76894,77124,77508,77692,77715,78252,78467],"is_not":false,"summary":null,"term":"GO:0006888"},{"annotations":[75616],"is_not":false,"summary":null,"term":"GO:0030968"},{"annotations":[71888],"is_not":false,"summary":null,"term":"GO:0061817"},{"annotations":[71814,72105,78628],"is_not":false,"summary":null,"term":"GO:0016197"},{"annotations":[71451,74371,76159,78300],"is_not":false,"summary":null,"term":"GO:0034058"},{"annotations":[75654],"is_not":false,"summary":null,"term":"GO:0007032"},{"annotations":[74943],"is_not":false,"summary":null,"term":"GO:0000455"},{"annotations":[73094],"is_not":false,"summary":null,"term":"GO:0035621"},{"annotations":[73414],"is_not":false,"summary":null,"term":"GO:0036503"},{"annotations":[70299,71121,71701,72933,73719,73927,75365,75435,75561,76252,78586,78718,78783,78849],"is_not":false,"summary":null,"term":"GO:0006696"},{"annotations":[70733],"is_not":false,"summary":null,"term":"GO:0070987"},{"annotations":[70732,73221,74501,76916],"is_not":false,"summary":null,"term":"GO:0042276"},{"annotations":[70815,77307],"is_not":false,"summary":null,"term":"GO:0030010"},{"annotations":[70263],"is_not":false,"summary":null,"term":"GO:0051654"},{"annotations":[72044],"is_not":false,"summary":null,"term":"GO:0034085"},{"annotations":[73006],"is_not":false,"summary":null,"term":"GO:0030950"},{"annotations":[75502],"is_not":false,"summary":null,"term":"GO:0007163"},{"annotations":[70532,70942,71192,71460,72034,73095,77023,78780],"is_not":false,"summary":null,"term":"GO:0006887"},{"annotations":[71502,71793,72356,73819,74499,76516],"is_not":false,"summary":null,"term":"GO:0043928"},{"annotations":[70880,71503,71794,72357,74500,76517],"is_not":false,"summary":null,"term":"GO:0000467"},{"annotations":[74379],"is_not":false,"summary":null,"term":"GO:0140570"},{"annotations":[77488],"is_not":false,"summary":null,"term":"GO:0006747"},{"annotations":[70861,77452],"is_not":false,"summary":null,"term":"GO:0045337"},{"annotations":[73925,78716],"is_not":false,"summary":null,"term":"GO:0010142"},{"annotations":[75363],"is_not":false,"summary":null,"term":"GO:0045338"},{"annotations":[73012],"is_not":false,"summary":null,"term":"GO:0001561"},{"annotations":[72932],"is_not":false,"summary":null,"term":"GO:0006635"},{"annotations":[70409,76100,76363],"is_not":false,"summary":null,"term":"GO:0006633"},{"annotations":[73304,78338],"is_not":false,"summary":null,"term":"GO:0030497"},{"annotations":[76728],"is_not":false,"summary":null,"term":"GO:0034625"},{"annotations":[76726],"is_not":false,"summary":null,"term":"GO:0019367"},{"annotations":[72256,76039,76733],"is_not":false,"summary":null,"term":"GO:0006631"},{"annotations":[72515],"is_not":false,"summary":null,"term":"GO:0009398"},{"annotations":[73524],"is_not":false,"summary":null,"term":"GO:1904947"},{"annotations":[71139,72155,73145],"is_not":false,"summary":null,"term":"GO:0046655"},{"annotations":[72465],"is_not":false,"summary":null,"term":"GO:0009396"},{"annotations":[77073],"is_not":false,"summary":null,"term":"GO:0046294"},{"annotations":[74560],"is_not":false,"summary":null,"term":"GO:0001732"},{"annotations":[73248,77306],"is_not":false,"summary":null,"term":"GO:0001731"},{"annotations":[76816],"is_not":false,"summary":null,"term":"GO:0030388"},{"annotations":[73177,74384,77521,78833],"is_not":false,"summary":null,"term":"GO:0006003"},{"annotations":[76817,77080],"is_not":false,"summary":null,"term":"GO:0006002"},{"annotations":[78011],"is_not":false,"summary":null,"term":"GO:0006106"},{"annotations":[70810,71595,72934,73117,77596],"is_not":false,"summary":null,"term":"GO:0070600"},{"annotations":[70473,70656,70806,71629,74397,78150],"is_not":false,"summary":null,"term":"GO:0009272"},{"annotations":[71037,72148,77082],"is_not":false,"summary":null,"term":"GO:0034221"},{"annotations":[71340,73591,74597,75542,75909,76808,78266,78496,76797],"is_not":false,"summary":null,"term":"GO:0031505"},{"annotations":[72232],"is_not":false,"summary":null,"term":"GO:0071966"},{"annotations":[72318],"is_not":false,"summary":null,"term":"GO:0007186"},{"annotations":[73635],"is_not":false,"summary":null,"term":"GO:0000082"},{"annotations":[76313],"is_not":false,"summary":null,"term":"GO:0006012"},{"annotations":[74859,76880],"is_not":false,"summary":null,"term":"GO:0009298"},{"annotations":[76912],"is_not":false,"summary":null,"term":"GO:0000349"},{"annotations":[72900,76477],"is_not":false,"summary":null,"term":"GO:0000350"},{"annotations":[70639,70710,72949,74385,76006],"is_not":false,"summary":null,"term":"GO:0009251"},{"annotations":[70402,70518],"is_not":false,"summary":null,"term":"GO:0051156"},{"annotations":[72129,74185,77828],"is_not":false,"summary":null,"term":"GO:0006006"},{"annotations":[78041],"is_not":false,"summary":null,"term":"GO:0006538"},{"annotations":[71479],"is_not":false,"summary":null,"term":"GO:0006542"},{"annotations":[71835,72205],"is_not":false,"summary":null,"term":"GO:0006541"},{"annotations":[71858,74538],"is_not":false,"summary":null,"term":"GO:0070681"},{"annotations":[70435,72639],"is_not":false,"summary":null,"term":"GO:0006424"},{"annotations":[76467,77566],"is_not":false,"summary":null,"term":"GO:0006750"},{"annotations":[75787],"is_not":false,"summary":null,"term":"GO:0006751"},{"annotations":[76103,77847],"is_not":false,"summary":null,"term":"GO:0006749"},{"annotations":[71983],"is_not":false,"summary":null,"term":"GO:0046166"},{"annotations":[71984,77455],"is_not":false,"summary":null,"term":"GO:0019563"},{"annotations":[71636],"is_not":false,"summary":null,"term":"GO:0046474"},{"annotations":[71679,75685,76308,77377],"is_not":false,"summary":null,"term":"GO:0046475"},{"annotations":[72005],"is_not":false,"summary":null,"term":"GO:0006545"},{"annotations":[72157,73147],"is_not":false,"summary":null,"term":"GO:0019264"},{"annotations":[73669,76980],"is_not":false,"summary":null,"term":"GO:0019464"},{"annotations":[76239],"is_not":false,"summary":null,"term":"GO:0034203"},{"annotations":[71795,72956],"is_not":false,"summary":null,"term":"GO:1903189"},{"annotations":[74135],"is_not":false,"summary":null,"term":"GO:0006177"},{"annotations":[74756],"is_not":false,"summary":null,"term":"GO:0032263"},{"annotations":[70841],"is_not":false,"summary":null,"term":"GO:0032468"},{"annotations":[71992,72274,73651,74002,74906,75653,76066,76622,77509],"is_not":false,"summary":null,"term":"GO:0007030"},{"annotations":[73421,75838,76717,76756,78367],"is_not":false,"summary":null,"term":"GO:0006895"},{"annotations":[76620],"is_not":false,"summary":null,"term":"GO:0043001"},{"annotations":[70943,72125,75289,76548],"is_not":false,"summary":null,"term":"GO:0006893"},{"annotations":[70164,73422,75424,76553,76718,76757,76979,78359],"is_not":false,"summary":null,"term":"GO:0006896"},{"annotations":[76616],"is_not":false,"summary":null,"term":"GO:0048194"},{"annotations":[70642],"is_not":false,"summary":null,"term":"GO:0048211"},{"annotations":[70151,70792,71328,71844,72920,73049,74376,74915,74934,75577,75618,76360,76504,76505,76657,76809,77206],"is_not":false,"summary":null,"term":"GO:0006506"},{"annotations":[72540],"is_not":false,"summary":null,"term":"GO:0006505"},{"annotations":[74300],"is_not":false,"summary":null,"term":"GO:0006183"},{"annotations":[77202,78597],"is_not":false,"summary":null,"term":"GO:0006784"},{"annotations":[73949],"is_not":false,"summary":null,"term":"GO:0006783"},{"annotations":[70564],"is_not":false,"summary":null,"term":"GO:0031507"},{"annotations":[71318,74958,75819,77317,78881],"is_not":false,"summary":null,"term":"GO:0000105"},{"annotations":[77449],"is_not":false,"summary":null,"term":"GO:0006427"},{"annotations":[70877],"is_not":false,"summary":null,"term":"GO:0071044"},{"annotations":[74107,77810],"is_not":false,"summary":null,"term":"GO:0050667"},{"annotations":[71258,73308],"is_not":false,"summary":null,"term":"GO:0009090"},{"annotations":[75360,75467],"is_not":false,"summary":null,"term":"GO:0009092"},{"annotations":[70428,71127,75129],"is_not":false,"summary":null,"term":"GO:0042744"},{"annotations":[74754],"is_not":false,"summary":null,"term":"GO:0046100"},{"annotations":[77610],"is_not":false,"summary":null,"term":"GO:0046040"},{"annotations":[74757],"is_not":false,"summary":null,"term":"GO:0032264"},{"annotations":[74950,76699],"is_not":false,"summary":null,"term":"GO:0000073"},{"annotations":[74988],"is_not":false,"summary":null,"term":"GO:0007007"},{"annotations":[70227],"is_not":false,"summary":null,"term":"GO:0006190"},{"annotations":[71238],"is_not":false,"summary":null,"term":"GO:0006020"},{"annotations":[71239,71446,74354,74796],"is_not":false,"summary":null,"term":"GO:0032958"},{"annotations":[73332,75440],"is_not":false,"summary":null,"term":"GO:0006673"},{"annotations":[74721,76985],"is_not":false,"summary":null,"term":"GO:0036297"},{"annotations":[70605,71117,71511,73254,74905,75423,76368,76896,77125,77716,78468],"is_not":false,"summary":null,"term":"GO:0006891"},{"annotations":[70455,71001,71718,72360,73203,73285,74571,77269,78661,78692],"is_not":false,"summary":null,"term":"GO:0006874"},{"annotations":[74507,77097],"is_not":false,"summary":null,"term":"GO:0006878"},{"annotations":[75494],"is_not":false,"summary":null,"term":"GO:0048312"},{"annotations":[70524,75405],"is_not":false,"summary":null,"term":"GO:0001678"},{"annotations":[71354,73917,74330,74508,76951,77098],"is_not":false,"summary":null,"term":"GO:0006879"},{"annotations":[70479,74042],"is_not":false,"summary":null,"term":"GO:0010961"},{"annotations":[70560,73316,75027],"is_not":false,"summary":null,"term":"GO:0030026"},{"annotations":[77911],"is_not":false,"summary":null,"term":"GO:0008298"},{"annotations":[70778,72241,77030],"is_not":false,"summary":null,"term":"GO:0030007"},{"annotations":[70105,70647,70715,71115,71977,72014,72033,72272,73251,74000,74178,74814,75099,75587,76064,76599,76627,76893,77368,77507,77756,78343,78482,78721],"is_not":false,"summary":null,"term":"GO:0006886"},{"annotations":[73318],"is_not":false,"summary":null,"term":"GO:0006880"},{"annotations":[71366,71569,72282,73062,75428,76154,76258,76417,76569,77051,77728,77820,77878],"is_not":false,"summary":null,"term":"GO:0035556"},{"annotations":[71966,76046],"is_not":false,"summary":null,"term":"GO:0032366"},{"annotations":[74373],"is_not":false,"summary":null,"term":"GO:0046907"},{"annotations":[72686,73878,74151,77190],"is_not":false,"summary":null,"term":"GO:0006882"},{"annotations":[76820],"is_not":false,"summary":null,"term":"GO:0036498"},{"annotations":[70580],"is_not":false,"summary":null,"term":"GO:0048250"},{"annotations":[70411,71565,71676,77792,78087],"is_not":false,"summary":null,"term":"GO:0016226"},{"annotations":[70885,73431],"is_not":false,"summary":null,"term":"GO:0006102"},{"annotations":[75556,76125,76682],"is_not":false,"summary":null,"term":"GO:0009097"},{"annotations":[71664,74670],"is_not":false,"summary":null,"term":"GO:0006428"},{"annotations":[74480],"is_not":false,"summary":null,"term":"GO:0009240"},{"annotations":[73923,76135,78584],"is_not":false,"summary":null,"term":"GO:0019287"},{"annotations":[77391],"is_not":false,"summary":null,"term":"GO:0008299"},{"annotations":[77574],"is_not":false,"summary":null,"term":"GO:0000742"},{"annotations":[78414],"is_not":false,"summary":null,"term":"GO:0051382"},{"annotations":[75165],"is_not":false,"summary":null,"term":"GO:0051383"},{"annotations":[75856,76771,77217,77970,78620],"is_not":false,"summary":null,"term":"GO:0019509"},{"annotations":[76885],"is_not":false,"summary":null,"term":"GO:0009094"},{"annotations":[76836],"is_not":false,"summary":null,"term":"GO:0055129"},{"annotations":[72998,78289],"is_not":false,"summary":null,"term":"GO:0006564"},{"annotations":[72159,73149,76684],"is_not":false,"summary":null,"term":"GO:0006565"},{"annotations":[78801],"is_not":false,"summary":null,"term":"GO:1903457"},{"annotations":[73638,74776,75804,76274],"is_not":false,"summary":null,"term":"GO:0045324"},{"annotations":[74745,75255,77983],"is_not":false,"summary":null,"term":"GO:0032511"},{"annotations":[70565],"is_not":false,"summary":null,"term":"GO:0006272"},{"annotations":[74307,75923,78432],"is_not":false,"summary":null,"term":"GO:0009098"},{"annotations":[75101,76929],"is_not":false,"summary":null,"term":"GO:0006429"},{"annotations":[70968,73748],"is_not":false,"summary":null,"term":"GO:0055088"},{"annotations":[75943],"is_not":false,"summary":null,"term":"GO:0030258"},{"annotations":[74554],"is_not":false,"summary":null,"term":"GO:0009107"},{"annotations":[72145],"is_not":false,"summary":null,"term":"GO:0042759"},{"annotations":[76296,77634],"is_not":false,"summary":null,"term":"GO:0001676"},{"annotations":[76295,77633],"is_not":false,"summary":null,"term":"GO:0035336"},{"annotations":[70447,74399,75534,75751,76482],"is_not":false,"summary":null,"term":"GO:0019878"},{"annotations":[73307],"is_not":false,"summary":null,"term":"GO:0009089"},{"annotations":[71808,73354],"is_not":false,"summary":null,"term":"GO:0006430"},{"annotations":[75417,76156,76275,77862],"is_not":false,"summary":null,"term":"GO:0016236"},{"annotations":[75024],"is_not":false,"summary":null,"term":"GO:1990616"},{"annotations":[70527,71454,73089],"is_not":false,"summary":null,"term":"GO:0030011"},{"annotations":[76991],"is_not":false,"summary":null,"term":"GO:0034088"},{"annotations":[70460],"is_not":false,"summary":null,"term":"GO:0043007"},{"annotations":[77745],"is_not":false,"summary":null,"term":"GO:0001193"},{"annotations":[73029,78012],"is_not":false,"summary":null,"term":"GO:0006108"},{"annotations":[70839],"is_not":false,"summary":null,"term":"GO:0071421"},{"annotations":[75403],"is_not":false,"summary":null,"term":"GO:0006013"},{"annotations":[74747,77997],"is_not":false,"summary":null,"term":"GO:0051999"},{"annotations":[71593,74633,76092,77769,77974,78189],"is_not":false,"summary":null,"term":"GO:0000460"},{"annotations":[77281,77547],"is_not":false,"summary":null,"term":"GO:0000466"},{"annotations":[77110],"is_not":false,"summary":null,"term":"GO:0000481"},{"annotations":[71594,74634,77587,77975,78190],"is_not":false,"summary":null,"term":"GO:0000470"},{"annotations":[70507,71262,72407,73141,73257,73388,73914,74389,74694,75532,76561,77280,77546,78305],"is_not":false,"summary":null,"term":"GO:0000463"},{"annotations":[70211,72444,73022,73195,73282,74297,75106,78170,78475],"is_not":false,"summary":null,"term":"GO:0030490"},{"annotations":[71107,71546,71694,71769,72536,72632,72874,73243,73855,74620,74628,74645,75123,75303,76131,77138,77298,78164,78376,78709],"is_not":false,"summary":null,"term":"GO:0000462"},{"annotations":[78100,78137],"is_not":false,"summary":null,"term":"GO:0042138"},{"annotations":[78139],"is_not":false,"summary":null,"term":"GO:0000706"},{"annotations":[77733],"is_not":false,"summary":null,"term":"GO:0044778"},{"annotations":[77376],"is_not":false,"summary":null,"term":"GO:0000707"},{"annotations":[77014],"is_not":false,"summary":null,"term":"GO:0051598"},{"annotations":[70800],"is_not":false,"summary":null,"term":"GO:0051754"},{"annotations":[71987],"is_not":false,"summary":null,"term":"GO:0061025"},{"annotations":[76705],"is_not":false,"summary":null,"term":"GO:0110051"},{"annotations":[71665],"is_not":false,"summary":null,"term":"GO:0030001"},{"annotations":[72834],"is_not":false,"summary":null,"term":"GO:0007091"},{"annotations":[71009,71811,74109,75306,75359,75611,77812],"is_not":false,"summary":null,"term":"GO:0009086"},{"annotations":[77260],"is_not":false,"summary":null,"term":"GO:0006431"},{"annotations":[72524,74062],"is_not":false,"summary":null,"term":"GO:0019243"},{"annotations":[77412],"is_not":false,"summary":null,"term":"GO:0016237"},{"annotations":[73620],"is_not":false,"summary":null,"term":"GO:1990810"},{"annotations":[74437,75383,76259,76418,76570],"is_not":false,"summary":null,"term":"GO:0000226"},{"annotations":[73506],"is_not":false,"summary":null,"term":"GO:0007018"},{"annotations":[71020],"is_not":false,"summary":null,"term":"GO:0007017"},{"annotations":[71302,71678,72198,72578,72691,73190],"is_not":false,"summary":null,"term":"GO:0006298"},{"annotations":[70658],"is_not":false,"summary":null,"term":"GO:0031930"},{"annotations":[71621,72437],"is_not":false,"summary":null,"term":"GO:0006843"},{"annotations":[70704],"is_not":false,"summary":null,"term":"GO:1990559"},{"annotations":[70469,72021,72432,75037,75979,77369],"is_not":false,"summary":null,"term":"GO:0033617"},{"annotations":[71311,75550],"is_not":false,"summary":null,"term":"GO:0043504"},{"annotations":[74239],"is_not":false,"summary":null,"term":"GO:0006264"},{"annotations":[78098],"is_not":false,"summary":null,"term":"GO:0097552"},{"annotations":[72041,73754,75315],"is_not":false,"summary":null,"term":"GO:0006123"},{"annotations":[74964,75314],"is_not":false,"summary":null,"term":"GO:0006122"},{"annotations":[72411],"is_not":false,"summary":null,"term":"GO:0008053"},{"annotations":[72721],"is_not":false,"summary":null,"term":"GO:0140053"},{"annotations":[75468,77939],"is_not":false,"summary":null,"term":"GO:0000002"},{"annotations":[72729],"is_not":false,"summary":null,"term":"GO:0070150"},{"annotations":[76721],"is_not":false,"summary":null,"term":"GO:1990575"},{"annotations":[76463],"is_not":false,"summary":null,"term":"GO:0045016"},{"annotations":[70265],"is_not":false,"summary":null,"term":"GO:0070096"},{"annotations":[76386,77010],"is_not":false,"summary":null,"term":"GO:0034982"},{"annotations":[73107,73630,77009],"is_not":false,"summary":null,"term":"GO:0033615"},{"annotations":[76172],"is_not":false,"summary":null,"term":"GO:0006850"},{"annotations":[70829,77008],"is_not":false,"summary":null,"term":"GO:0034553"},{"annotations":[77200],"is_not":false,"summary":null,"term":"GO:0034551"},{"annotations":[70898],"is_not":false,"summary":null,"term":"GO:0000965"},{"annotations":[78027],"is_not":false,"summary":null,"term":"GO:0000964"},{"annotations":[72858],"is_not":false,"summary":null,"term":"GO:0070158"},{"annotations":[70388,71860,74540,74669,74709,75142,76288,76928,77048,77448,77981],"is_not":false,"summary":null,"term":"GO:0032543"},{"annotations":[73265,78569],"is_not":false,"summary":null,"term":"GO:0070125"},{"annotations":[73803,77525],"is_not":false,"summary":null,"term":"GO:0070124"},{"annotations":[76423],"is_not":false,"summary":null,"term":"GO:0070126"},{"annotations":[77025],"is_not":false,"summary":null,"term":"GO:0070901"},{"annotations":[75013],"is_not":false,"summary":null,"term":"GO:0072670"},{"annotations":[75406],"is_not":false,"summary":null,"term":"GO:0070899"},{"annotations":[71598],"is_not":false,"summary":null,"term":"GO:0070183"},{"annotations":[76537],"is_not":false,"summary":null,"term":"GO:0034514"},{"annotations":[73641,74252,74779,76217,78670],"is_not":false,"summary":null,"term":"GO:0007005"},{"annotations":[70266,78524],"is_not":false,"summary":null,"term":"GO:1990456"},{"annotations":[72475],"is_not":false,"summary":null,"term":"GO:0000423"},{"annotations":[72462],"is_not":false,"summary":null,"term":"GO:1903475"},{"annotations":[76447],"is_not":false,"summary":null,"term":"GO:1903479"},{"annotations":[74438],"is_not":false,"summary":null,"term":"GO:0000278"},{"annotations":[70783,71920],"is_not":false,"summary":null,"term":"GO:0007076"},{"annotations":[78574],"is_not":false,"summary":null,"term":"GO:0000281"},{"annotations":[78876],"is_not":false,"summary":null,"term":"GO:0140278"},{"annotations":[78805],"is_not":false,"summary":null,"term":"GO:0044773"},{"annotations":[71246,71980,74473,77737,78084],"is_not":false,"summary":null,"term":"GO:0033314"},{"annotations":[74157,77963,70301,71895,71981,72699,73336,74656,76148,77578,78085],"is_not":false,"summary":null,"term":"GO:1902975"},{"annotations":[71894],"is_not":false,"summary":null,"term":"GO:1902977"},{"annotations":[71982,74661,78101],"is_not":false,"summary":null,"term":"GO:0007095"},{"annotations":[73895,77736,77917,78099],"is_not":false,"summary":null,"term":"GO:0031573"},{"annotations":[72229,74585,74980,76214],"is_not":false,"summary":null,"term":"GO:0006312"},{"annotations":[70114,71972],"is_not":false,"summary":null,"term":"GO:0007064"},{"annotations":[71359],"is_not":false,"summary":null,"term":"GO:0000070"},{"annotations":[74873],"is_not":false,"summary":null,"term":"GO:0051228"},{"annotations":[71686,75117,75492],"is_not":false,"summary":null,"term":"GO:0007052"},{"annotations":[75333],"is_not":false,"summary":null,"term":"GO:0044820"},{"annotations":[72603,75081,78327,78888],"is_not":false,"summary":null,"term":"GO:0019941"},{"annotations":[70323],"is_not":false,"summary":null,"term":"GO:0050801"},{"annotations":[72901],"is_not":false,"summary":null,"term":"GO:0000389"},{"annotations":[78134],"is_not":false,"summary":null,"term":"GO:0000395"},{"annotations":[75539],"is_not":false,"summary":null,"term":"GO:0006402"},{"annotations":[77109,78117,70589,70698,71049,71266,71722,71864,71944,72151,72666,72768,73001,73056,73632,73767,73810,73814,74082,74105,74188,74423,75146,75204,75253,75783,76112,76324,76370,76383,76605,76790,76913,77228,77558,78068,78106,78476,78531,78763],"is_not":false,"summary":null,"term":"GO:0045292"},{"annotations":[72451,72684,73766,75937,76542,78624],"is_not":false,"summary":null,"term":"GO:0006406"},{"annotations":[70930,72702,75063,77343,78827],"is_not":false,"summary":null,"term":"GO:1990481"},{"annotations":[74017,76337],"is_not":false,"summary":null,"term":"GO:0006376"},{"annotations":[73956],"is_not":false,"summary":null,"term":"GO:0034496"},{"annotations":[72090,72785],"is_not":false,"summary":null,"term":"GO:1904679"},{"annotations":[76117,77276],"is_not":false,"summary":null,"term":"GO:0006491"},{"annotations":[71090],"is_not":false,"summary":null,"term":"GO:0034356"},{"annotations":[74170,76473],"is_not":false,"summary":null,"term":"GO:0009435"},{"annotations":[72237],"is_not":false,"summary":null,"term":"GO:0019677"},{"annotations":[78528],"is_not":false,"summary":null,"term":"GO:0034355"},{"annotations":[72866],"is_not":false,"summary":null,"term":"GO:0110155"},{"annotations":[72239],"is_not":false,"summary":null,"term":"GO:0006734"},{"annotations":[74284,78643],"is_not":false,"summary":null,"term":"GO:0006116"},{"annotations":[71228,76883,78451],"is_not":false,"summary":null,"term":"GO:0006741"},{"annotations":[72240],"is_not":false,"summary":null,"term":"GO:0006742"},{"annotations":[74030],"is_not":false,"summary":null,"term":"GO:0034316"},{"annotations":[70256,72404],"is_not":false,"summary":null,"term":"GO:1990625"},{"annotations":[71060],"is_not":false,"summary":null,"term":"GO:0045717"},{"annotations":[70786,77405],"is_not":false,"summary":null,"term":"GO:0110031"},{"annotations":[76149,77815],"is_not":false,"summary":null,"term":"GO:0045719"},{"annotations":[72769,75445],"is_not":false,"summary":null,"term":"GO:0045820"},{"annotations":[76316],"is_not":false,"summary":null,"term":"GO:0032435"},{"annotations":[72247],"is_not":false,"summary":null,"term":"GO:0046580"},{"annotations":[76344],"is_not":false,"summary":null,"term":"GO:0061188"},{"annotations":[72126],"is_not":false,"summary":null,"term":"GO:1902369"},{"annotations":[72460],"is_not":false,"summary":null,"term":"GO:0031030"},{"annotations":[76343],"is_not":false,"summary":null,"term":"GO:0061186"},{"annotations":[71670,73320],"is_not":false,"summary":null,"term":"GO:1904262"},{"annotations":[70660,71821,73382,73487,73601,73782,75868,76201],"is_not":false,"summary":null,"term":"GO:0000122"},{"annotations":[73478],"is_not":false,"summary":null,"term":"GO:0016480"},{"annotations":[73953],"is_not":false,"summary":null,"term":"GO:0046461"},{"annotations":[70225],"is_not":false,"summary":null,"term":"GO:0071590"},{"annotations":[70226],"is_not":false,"summary":null,"term":"GO:0071592"},{"annotations":[73358,74418,76236],"is_not":false,"summary":null,"term":"GO:0006607"},{"annotations":[74084],"is_not":false,"summary":null,"term":"GO:0070651"},{"annotations":[71059,74439],"is_not":false,"summary":null,"term":"GO:0000280"},{"annotations":[77034],"is_not":false,"summary":null,"term":"GO:0006998"},{"annotations":[70932],"is_not":false,"summary":null,"term":"GO:0071765"},{"annotations":[71990],"is_not":false,"summary":null,"term":"GO:0031468"},{"annotations":[71052,74432],"is_not":false,"summary":null,"term":"GO:0098863"},{"annotations":[71494,71785,72348,72977,74034],"is_not":false,"summary":null,"term":"GO:0071028"},{"annotations":[70352],"is_not":false,"summary":null,"term":"GO:0071031"},{"annotations":[70876],"is_not":false,"summary":null,"term":"GO:0071040"},{"annotations":[70357,70875],"is_not":false,"summary":null,"term":"GO:0071039"},{"annotations":[71497,71788,72351],"is_not":false,"summary":null,"term":"GO:0071042"},{"annotations":[70353,70871,71495,71786,72349,74494,76511],"is_not":false,"summary":null,"term":"GO:0071035"},{"annotations":[70354,70872],"is_not":false,"summary":null,"term":"GO:0071036"},{"annotations":[70355,70873],"is_not":false,"summary":null,"term":"GO:0071037"},{"annotations":[70356,70874,71496,71787,72350,74495,76512],"is_not":false,"summary":null,"term":"GO:0071038"},{"annotations":[75471,76237],"is_not":false,"summary":null,"term":"GO:0006999"},{"annotations":[75709],"is_not":false,"summary":null,"term":"GO:0071630"},{"annotations":[72867,78582],"is_not":false,"summary":null,"term":"GO:0000956"},{"annotations":[74712],"is_not":false,"summary":null,"term":"GO:0070478"},{"annotations":[70852,75739,78075],"is_not":false,"summary":null,"term":"GO:0000288"},{"annotations":[72626],"is_not":false,"summary":null,"term":"GO:0000291"},{"annotations":[74085],"is_not":false,"summary":null,"term":"GO:0070966"},{"annotations":[73297],"is_not":false,"summary":null,"term":"GO:0000294"},{"annotations":[71370,72427,77703],"is_not":false,"summary":null,"term":"GO:0000289"},{"annotations":[77130],"is_not":false,"summary":null,"term":"GO:0015851"},{"annotations":[75133,77902,78461],"is_not":false,"summary":null,"term":"GO:0042790"},{"annotations":[71846,73366,78547],"is_not":false,"summary":null,"term":"GO:0044804"},{"annotations":[70725],"is_not":false,"summary":null,"term":"GO:0009134"},{"annotations":[70995],"is_not":false,"summary":null,"term":"GO:0009141"},{"annotations":[74167],"is_not":false,"summary":null,"term":"GO:0009117"},{"annotations":[70333,72197,72577,73694,75477,77738],"is_not":false,"summary":null,"term":"GO:0006289"},{"annotations":[70213,74393],"is_not":false,"summary":null,"term":"GO:1901255"},{"annotations":[73689,74594,76003,78818],"is_not":false,"summary":null,"term":"GO:0006297"},{"annotations":[78895],"is_not":false,"summary":null,"term":"GO:0071562"},{"annotations":[71968],"is_not":false,"summary":null,"term":"GO:1903461"},{"annotations":[78485],"is_not":false,"summary":null,"term":"GO:0006490"},{"annotations":[78112],"is_not":false,"summary":null,"term":"GO:1901565"},{"annotations":[72220,75843],"is_not":false,"summary":null,"term":"GO:0006592"},{"annotations":[72203],"is_not":false,"summary":null,"term":"GO:0006107"},{"annotations":[71762,73939,75208,75876],"is_not":false,"summary":null,"term":"GO:0033962"},{"annotations":[70496,72911],"is_not":false,"summary":null,"term":"GO:0038066"},{"annotations":[72275,76523],"is_not":false,"summary":null,"term":"GO:0015940"},{"annotations":[72376],"is_not":false,"summary":null,"term":"GO:0098717"},{"annotations":[72853],"is_not":false,"summary":null,"term":"GO:0008153"},{"annotations":[72875,73480,74069],"is_not":false,"summary":null,"term":"GO:0009052"},{"annotations":[72127,72696,74183,77826,78844],"is_not":false,"summary":null,"term":"GO:0009051"},{"annotations":[72763,76501],"is_not":false,"summary":null,"term":"GO:0043171"},{"annotations":[70159],"is_not":false,"summary":null,"term":"GO:0006518"},{"annotations":[75692],"is_not":false,"summary":null,"term":"GO:0016559"},{"annotations":[78598],"is_not":false,"summary":null,"term":"GO:0007031"},{"annotations":[76587,77492,77707],"is_not":false,"summary":null,"term":"GO:0006432"},{"annotations":[70974,71491,71613],"is_not":false,"summary":null,"term":"GO:0006654"},{"annotations":[77012],"is_not":false,"summary":null,"term":"GO:0006656"},{"annotations":[71195,73113,74961,77876],"is_not":false,"summary":null,"term":"GO:0006646"},{"annotations":[71903],"is_not":false,"summary":null,"term":"GO:0036149"},{"annotations":[75749,78696],"is_not":false,"summary":null,"term":"GO:0006661"},{"annotations":[71388],"is_not":false,"summary":null,"term":"GO:0036092"},{"annotations":[71390,71799,72633],"is_not":false,"summary":null,"term":"GO:0048015"},{"annotations":[75760],"is_not":false,"summary":null,"term":"GO:1990536"},{"annotations":[70253,70795,77329],"is_not":false,"summary":null,"term":"GO:0008654"},{"annotations":[73963],"is_not":false,"summary":null,"term":"GO:0009395"},{"annotations":[72706,74077,74346],"is_not":false,"summary":null,"term":"GO:0045332"},{"annotations":[70917],"is_not":false,"summary":null,"term":"GO:0046938"},{"annotations":[70531,71459,72167,72474,72570,72908,73093,73219,73957,78160,78349],"is_not":false,"summary":null,"term":"GO:0034727"},{"annotations":[76664],"is_not":false,"summary":null,"term":"GO:0032220"},{"annotations":[72938],"is_not":false,"summary":null,"term":"GO:0017121"},{"annotations":[71378,72789,73232,73673,73967,74902,78840],"is_not":false,"summary":null,"term":"GO:0016973"},{"annotations":[70878,72978,74035,74496,75391,76513],"is_not":false,"summary":null,"term":"GO:0071051"},{"annotations":[70695],"is_not":false,"summary":null,"term":"GO:0006798"},{"annotations":[71084],"is_not":false,"summary":null,"term":"GO:0006797"},{"annotations":[73322],"is_not":false,"summary":null,"term":"GO:0010508"},{"annotations":[70100],"is_not":false,"summary":null,"term":"GO:2000767"},{"annotations":[70616,78424],"is_not":false,"summary":null,"term":"GO:0032786"},{"annotations":[70817,73260],"is_not":false,"summary":null,"term":"GO:0010971"},{"annotations":[73261],"is_not":false,"summary":null,"term":"GO:0110032"},{"annotations":[74841],"is_not":false,"summary":null,"term":"GO:0016239"},{"annotations":[76891],"is_not":false,"summary":null,"term":"GO:0140281"},{"annotations":[73594,74698,74760],"is_not":false,"summary":null,"term":"GO:0048026"},{"annotations":[72622],"is_not":false,"summary":null,"term":"GO:0060213"},{"annotations":[76653],"is_not":false,"summary":null,"term":"GO:0032436"},{"annotations":[71468],"is_not":false,"summary":null,"term":"GO:0070863"},{"annotations":[76899],"is_not":false,"summary":null,"term":"GO:2000234"},{"annotations":[72893],"is_not":false,"summary":null,"term":"GO:0032008"},{"annotations":[74840,75198,75888],"is_not":false,"summary":null,"term":"GO:1904263"},{"annotations":[72922,75298,76898,78028],"is_not":false,"summary":null,"term":"GO:0045943"},{"annotations":[70552,70887,71186,71523,71771,71820,71901,73179,73348,73486,74504,74879,75701,75865,76679,77094,77855],"is_not":false,"summary":null,"term":"GO:0045944"},{"annotations":[71167,71646,77127],"is_not":false,"summary":null,"term":"GO:0032968"},{"annotations":[72620],"is_not":false,"summary":null,"term":"GO:0045948"},{"annotations":[74350,78243],"is_not":false,"summary":null,"term":"GO:0006892"},{"annotations":[75022],"is_not":false,"summary":null,"term":"GO:0000973"},{"annotations":[70224,74603],"is_not":false,"summary":null,"term":"GO:0006620"},{"annotations":[72945,72992,73397,78852],"is_not":false,"summary":null,"term":"GO:0031204"},{"annotations":[70780,72243],"is_not":false,"summary":null,"term":"GO:1990573"},{"annotations":[78664],"is_not":false,"summary":null,"term":"GO:0071805"},{"annotations":[70568,77056],"is_not":false,"summary":null,"term":"GO:0010133"},{"annotations":[70824,76320],"is_not":false,"summary":null,"term":"GO:0006433"},{"annotations":[70906,74716,76016,77749],"is_not":false,"summary":null,"term":"GO:0010499"},{"annotations":[78785],"is_not":false,"summary":null,"term":"GO:0070682"},{"annotations":[71308,71484,71734,71915,71991,72883,73647,73698,75175,75567,76373,76411,76857,77064,77805,78020,78354,78409,78794],"is_not":false,"summary":null,"term":"GO:0043161"},{"annotations":[75368,78795],"is_not":false,"summary":null,"term":"GO:0007039"},{"annotations":[71233,75375,77732],"is_not":false,"summary":null,"term":"GO:0000338"},{"annotations":[72894],"is_not":false,"summary":null,"term":"GO:0032527"},{"annotations":[71642],"is_not":false,"summary":null,"term":"GO:0006611"},{"annotations":[70112,70342,72521,73391,74279,74737,75386,75602,75630,75706,75813,76849,76872,76923,76942,77238,77834,78210,78396,78404,78619],"is_not":false,"summary":null,"term":"GO:0006457"},{"annotations":[71950,74860],"is_not":false,"summary":null,"term":"GO:0006486"},{"annotations":[75986,76745,77835,78725],"is_not":false,"summary":null,"term":"GO:0017183"},{"annotations":[76055,76534,77247],"is_not":false,"summary":null,"term":"GO:0045041"},{"annotations":[70360,71144,71464,71515,71641,72533,72669,72685,72895,73233,73345,73582,73841,73968,74546,74903,75021,75086,75463,76713,77402,78230,78625,78714,78841],"is_not":false,"summary":null,"term":"GO:0006606"},{"annotations":[70328,70911,72130,73126],"is_not":false,"summary":null,"term":"GO:0016558"},{"annotations":[70938,73290],"is_not":false,"summary":null,"term":"GO:0016560"},{"annotations":[73014,73736,75007,76838],"is_not":false,"summary":null,"term":"GO:0045039"},{"annotations":[77199],"is_not":false,"summary":null,"term":"GO:0032979"},{"annotations":[70260,75755],"is_not":false,"summary":null,"term":"GO:0045040"},{"annotations":[71063],"is_not":false,"summary":null,"term":"GO:0070973"},{"annotations":[71954,76479],"is_not":false,"summary":null,"term":"GO:0072657"},{"annotations":[74542,76233],"is_not":false,"summary":null,"term":"GO:0036228"},{"annotations":[70601,71548],"is_not":false,"summary":null,"term":"GO:0072659"},{"annotations":[70909,78606],"is_not":false,"summary":null,"term":"GO:0106035"},{"annotations":[71542],"is_not":false,"summary":null,"term":"GO:0097428"},{"annotations":[77248],"is_not":false,"summary":null,"term":"GO:0022417"},{"annotations":[70239,70728,71289,71632,71909,73166,74120,74316,74788,75119,75433,76022,76107,76407,76963,77083,77666,77722,78056,78484,78515,78893],"is_not":false,"summary":null,"term":"GO:0006487"},{"annotations":[73990,75671,77643,77929,78108],"is_not":false,"summary":null,"term":"GO:0018279"},{"annotations":[71534,72600,73678,74407,78323],"is_not":false,"summary":null,"term":"GO:0045116"},{"annotations":[76108,78057,78260],"is_not":false,"summary":null,"term":"GO:0006493"},{"annotations":[70160,75949,77119,78565,78782],"is_not":false,"summary":null,"term":"GO:0006627"},{"annotations":[72297,74288,76243,76387,77115],"is_not":false,"summary":null,"term":"GO:0006515"},{"annotations":[70893,71413,71756,72364,72478,74075,74630,75239,76607,76996,77788,78759],"is_not":false,"summary":null,"term":"GO:0042026"},{"annotations":[72371,72381,74846,75089],"is_not":false,"summary":null,"term":"GO:0016925"},{"annotations":[71152,72677,74256,74520,75323],"is_not":false,"summary":null,"term":"GO:0006612"},{"annotations":[71452,73640,74778,76160,76279,76716,76978,78793],"is_not":false,"summary":null,"term":"GO:0006623"},{"annotations":[70979,71068,72213,72314,73109,73423,76758,77256,77312],"is_not":false,"summary":null,"term":"GO:0043328"},{"annotations":[74076,77789],"is_not":false,"summary":null,"term":"GO:0043335"},{"annotations":[70764,74025],"is_not":false,"summary":null,"term":"GO:0032447"},{"annotations":[73752,74214],"is_not":false,"summary":null,"term":"GO:0022618"},{"annotations":[70685,76497],"is_not":false,"summary":null,"term":"GO:0051603"},{"annotations":[72611],"is_not":false,"summary":null,"term":"GO:1902600"},{"annotations":[78513],"is_not":false,"summary":null,"term":"GO:0006782"},{"annotations":[70635],"is_not":false,"summary":null,"term":"GO:0009113"},{"annotations":[73241],"is_not":false,"summary":null,"term":"GO:0006145"},{"annotations":[70339,74864],"is_not":false,"summary":null,"term":"GO:0006144"},{"annotations":[74673],"is_not":false,"summary":null,"term":"GO:0006152"},{"annotations":[72401,73518],"is_not":false,"summary":null,"term":"GO:0006164"},{"annotations":[73224],"is_not":false,"summary":null,"term":"GO:0006166"},{"annotations":[75031],"is_not":false,"summary":null,"term":"GO:0033387"},{"annotations":[70680],"is_not":false,"summary":null,"term":"GO:0015847"},{"annotations":[74640,76934],"is_not":false,"summary":null,"term":"GO:0009443"},{"annotations":[74730],"is_not":false,"summary":null,"term":"GO:0042823"},{"annotations":[74728],"is_not":false,"summary":null,"term":"GO:0008615"},{"annotations":[77320],"is_not":false,"summary":null,"term":"GO:0008614"},{"annotations":[74044],"is_not":false,"summary":null,"term":"GO:0006206"},{"annotations":[77938],"is_not":false,"summary":null,"term":"GO:1990519"},{"annotations":[73120],"is_not":false,"summary":null,"term":"GO:0046132"},{"annotations":[72837,73028],"is_not":false,"summary":null,"term":"GO:0006090"},{"annotations":[72739],"is_not":false,"summary":null,"term":"GO:0031623"},{"annotations":[70957,76672,78138],"is_not":false,"summary":null,"term":"GO:0007131"},{"annotations":[74725,76669],"is_not":false,"summary":null,"term":"GO:0000725"},{"annotations":[71168],"is_not":false,"summary":null,"term":"GO:0034402"},{"annotations":[77670],"is_not":false,"summary":null,"term":"GO:0032956"},{"annotations":[76298,78222],"is_not":false,"summary":null,"term":"GO:0030833"},{"annotations":[77142],"is_not":false,"summary":null,"term":"GO:0031991"},{"annotations":[72567,77215,78157],"is_not":false,"summary":null,"term":"GO:0010506"},{"annotations":[75068],"is_not":false,"summary":null,"term":"GO:0045540"},{"annotations":[71471],"is_not":false,"summary":null,"term":"GO:0003400"},{"annotations":[74819,77143],"is_not":false,"summary":null,"term":"GO:0032955"},{"annotations":[70466,71856,72055,72851,74412,74928,75195,75412,77499],"is_not":false,"summary":null,"term":"GO:0006355"},{"annotations":[76392,77335],"is_not":false,"summary":null,"term":"GO:0030100"},{"annotations":[70461],"is_not":false,"summary":null,"term":"GO:0007096"},{"annotations":[71549],"is_not":false,"summary":null,"term":"GO:0017157"},{"annotations":[71558],"is_not":false,"summary":null,"term":"GO:0060237"},{"annotations":[70623,73078],"is_not":false,"summary":null,"term":"GO:0010468"},{"annotations":[71015,71661,72984,76459],"is_not":false,"summary":null,"term":"GO:0051453"},{"annotations":[74266,78912],"is_not":false,"summary":null,"term":"GO:0043408"},{"annotations":[71091,73276,73760],"is_not":false,"summary":null,"term":"GO:0007346"},{"annotations":[75273],"is_not":false,"summary":null,"term":"GO:0050684"},{"annotations":[70659],"is_not":false,"summary":null,"term":"GO:0006808"},{"annotations":[75448],"is_not":false,"summary":null,"term":"GO:0043456"},{"annotations":[71965],"is_not":false,"summary":null,"term":"GO:0097036"},{"annotations":[76425,77099],"is_not":false,"summary":null,"term":"GO:0061136"},{"annotations":[75996],"is_not":false,"summary":null,"term":"GO:0032210"},{"annotations":[73567],"is_not":false,"summary":null,"term":"GO:0006356"},{"annotations":[70617,71782,72171,72559,72610,72809,72813,73100,73556,73695,75321,75742,76439,76635,77232,77860,78145,78747,78907],"is_not":false,"summary":null,"term":"GO:0006357"},{"annotations":[73568,75633,77041],"is_not":false,"summary":null,"term":"GO:0006359"},{"annotations":[77602],"is_not":false,"summary":null,"term":"GO:0006450"},{"annotations":[72386],"is_not":false,"summary":null,"term":"GO:0032889"},{"annotations":[72634],"is_not":false,"summary":null,"term":"GO:0051209"},{"annotations":[77153,78766],"is_not":false,"summary":null,"term":"GO:0043111"},{"annotations":[77916,78052],"is_not":false,"summary":null,"term":"GO:0031297"},{"annotations":[74785],"is_not":false,"summary":null,"term":"GO:0071932"},{"annotations":[70116,75770,77250],"is_not":false,"summary":null,"term":"GO:0072344"},{"annotations":[73896,74395,77919],"is_not":false,"summary":null,"term":"GO:0000712"},{"annotations":[72661,78684],"is_not":false,"summary":null,"term":"GO:0034976"},{"annotations":[76918],"is_not":false,"summary":null,"term":"GO:0009314"},{"annotations":[72562,72906,78152,78347],"is_not":false,"summary":null,"term":"GO:0061709"},{"annotations":[74878,77771],"is_not":false,"summary":null,"term":"GO:0030970"},{"annotations":[70163,70714,71078,71564,71660,71976,75098,75246,75422,76263,76564,76626,77501,78358,78481],"is_not":false,"summary":null,"term":"GO:0042147"},{"annotations":[71116,71216,72058,72596,73253,73539,74924,76621,76677,76895],"is_not":false,"summary":null,"term":"GO:0006890"},{"annotations":[71364,75655,76944,77512],"is_not":false,"summary":null,"term":"GO:0009231"},{"annotations":[77697],"is_not":false,"summary":null,"term":"GO:0034517"},{"annotations":[73795],"is_not":false,"summary":null,"term":"GO:0046390"},{"annotations":[73605],"is_not":false,"summary":null,"term":"GO:0019693"},{"annotations":[70234,70349,70504,70699,71926,72500,72718,73596,73840,74446,75339,75349,75834,75855,75919,76084,76303,78738],"is_not":false,"summary":null,"term":"GO:0042273"},{"annotations":[75316,75790,76086,78626],"is_not":false,"summary":null,"term":"GO:0000055"},{"annotations":[70285,70320,71768,71842,72549,72946,73196,74142,74264,74274,74404,74674,75746,75793,76221],"is_not":false,"summary":null,"term":"GO:0000028"},{"annotations":[70175,72719,72846,73979],"is_not":false,"summary":null,"term":"GO:0042274"},{"annotations":[70178,70594,75317,78627],"is_not":false,"summary":null,"term":"GO:0000056"},{"annotations":[71516,75529,76753,78188],"is_not":false,"summary":null,"term":"GO:0000054"},{"annotations":[72878],"is_not":false,"summary":null,"term":"GO:0042254"},{"annotations":[70867,74087],"is_not":false,"summary":null,"term":"GO:0032790"},{"annotations":[70117,75772],"is_not":false,"summary":null,"term":"GO:1990116"},{"annotations":[73555],"is_not":false,"summary":null,"term":"GO:1904802"},{"annotations":[77134],"is_not":false,"summary":null,"term":"GO:0031123"},{"annotations":[70897],"is_not":false,"summary":null,"term":"GO:0006401"},{"annotations":[74545,75020,75606,78713],"is_not":false,"summary":null,"term":"GO:0006405"},{"annotations":[77364],"is_not":false,"summary":null,"term":"GO:1990113"},{"annotations":[76736],"is_not":false,"summary":null,"term":"GO:0001188"},{"annotations":[77365],"is_not":false,"summary":null,"term":"GO:1990114"},{"annotations":[70756,71372,71932,73984,75964],"is_not":false,"summary":null,"term":"GO:0051123"},{"annotations":[77366],"is_not":false,"summary":null,"term":"GO:1990115"},{"annotations":[71872],"is_not":false,"summary":null,"term":"GO:0070898"},{"annotations":[74834,78588],"is_not":false,"summary":null,"term":"GO:0070476"},{"annotations":[72102],"is_not":false,"summary":null,"term":"GO:1904812"},{"annotations":[74884,77144,77585,77593,78256],"is_not":false,"summary":null,"term":"GO:0070475"},{"annotations":[76804],"is_not":false,"summary":null,"term":"GO:0016075"},{"annotations":[74448,77545,77994],"is_not":false,"summary":null,"term":"GO:0031167"},{"annotations":[70819,71442,72250,73374,73781,73980,74191,74241,74263,74701,74870,75259,75342,75848,75954,77567,78385,78542,78581,78773],"is_not":false,"summary":null,"term":"GO:0006364"},{"annotations":[78828],"is_not":false,"summary":null,"term":"GO:0031118"},{"annotations":[74617],"is_not":false,"summary":null,"term":"GO:0006556"},{"annotations":[76520],"is_not":false,"summary":null,"term":"GO:0033353"},{"annotations":[75612],"is_not":false,"summary":null,"term":"GO:0033528"},{"annotations":[71958],"is_not":false,"summary":null,"term":"GO:0010265"},{"annotations":[73732,78705],"is_not":false,"summary":null,"term":"GO:0031146"},{"annotations":[70485],"is_not":false,"summary":null,"term":"GO:0031106"},{"annotations":[72064,75043],"is_not":false,"summary":null,"term":"GO:0042989"},{"annotations":[75903],"is_not":false,"summary":null,"term":"GO:0006434"},{"annotations":[73542,75370],"is_not":false,"summary":null,"term":"GO:0006465"},{"annotations":[71080,71171,71711,72260,73105,73136,73453,73706,76334,76649,77351],"is_not":false,"summary":null,"term":"GO:0007165"},{"annotations":[71580],"is_not":false,"summary":null,"term":"GO:0030466"},{"annotations":[71727],"is_not":false,"summary":null,"term":"GO:0030422"},{"annotations":[71531,75895],"is_not":false,"summary":null,"term":"GO:0019354"},{"annotations":[77442],"is_not":false,"summary":null,"term":"GO:0071171"},{"annotations":[72778],"is_not":false,"summary":null,"term":"GO:0034462"},{"annotations":[75075],"is_not":false,"summary":null,"term":"GO:0035493"},{"annotations":[75586],"is_not":false,"summary":null,"term":"GO:0035494"},{"annotations":[74057],"is_not":false,"summary":null,"term":"GO:0000454"},{"annotations":[78302],"is_not":false,"summary":null,"term":"GO:0048254"},{"annotations":[74768],"is_not":false,"summary":null,"term":"GO:0034247"},{"annotations":[75190],"is_not":false,"summary":null,"term":"GO:0040031"},{"annotations":[78829],"is_not":false,"summary":null,"term":"GO:0031120"},{"annotations":[72844],"is_not":false,"summary":null,"term":"GO:0006062"},{"annotations":[74366,76576],"is_not":false,"summary":null,"term":"GO:0008295"},{"annotations":[76578],"is_not":false,"summary":null,"term":"GO:0006597"},{"annotations":[72417,72743,73303,73331,76727],"is_not":false,"summary":null,"term":"GO:0030148"},{"annotations":[71967],"is_not":false,"summary":null,"term":"GO:0006665"},{"annotations":[73426,75969,77648],"is_not":false,"summary":null,"term":"GO:0046512"},{"annotations":[71943,73547,75277,77583],"is_not":false,"summary":null,"term":"GO:0000245"},{"annotations":[71879,74322,77592],"is_not":false,"summary":null,"term":"GO:0000390"},{"annotations":[71763,72557,74997,76081,77951],"is_not":false,"summary":null,"term":"GO:0000387"},{"annotations":[72488,75458,76323],"is_not":false,"summary":null,"term":"GO:0000244"},{"annotations":[70223],"is_not":false,"summary":null,"term":"GO:0006614"},{"annotations":[72994,73399,74825],"is_not":false,"summary":null,"term":"GO:0006616"},{"annotations":[71962],"is_not":false,"summary":null,"term":"GO:0016125"},{"annotations":[75877],"is_not":false,"summary":null,"term":"GO:0034063"},{"annotations":[77007],"is_not":false,"summary":null,"term":"GO:0006105"},{"annotations":[71778],"is_not":false,"summary":null,"term":"GO:0006104"},{"annotations":[75915],"is_not":false,"summary":null,"term":"GO:0005987"},{"annotations":[74356,77636],"is_not":false,"summary":null,"term":"GO:0000103"},{"annotations":[76874],"is_not":false,"summary":null,"term":"GO:0010134"},{"annotations":[76873,78534],"is_not":false,"summary":null,"term":"GO:0019379"},{"annotations":[75520],"is_not":false,"summary":null,"term":"GO:0070221"},{"annotations":[70620,74655],"is_not":false,"summary":null,"term":"GO:1902981"},{"annotations":[72657],"is_not":false,"summary":null,"term":"GO:0071816"},{"annotations":[75995],"is_not":false,"summary":null,"term":"GO:0016233"},{"annotations":[70613,71067,71674,71706,77060,77739,78102],"is_not":false,"summary":null,"term":"GO:0000723"},{"annotations":[70926],"is_not":false,"summary":null,"term":"GO:0007004"},{"annotations":[73805],"is_not":false,"summary":null,"term":"GO:0010833"},{"annotations":[75019],"is_not":false,"summary":null,"term":"GO:0034398"},{"annotations":[70550,73376,73863,73972],"is_not":false,"summary":null,"term":"GO:0006369"},{"annotations":[70377],"is_not":false,"summary":null,"term":"GO:0006729"},{"annotations":[71138,78398],"is_not":false,"summary":null,"term":"GO:0046654"},{"annotations":[71010,71812,72466,75060,75720],"is_not":false,"summary":null,"term":"GO:0035999"},{"annotations":[72187],"is_not":false,"summary":null,"term":"GO:0046901"},{"annotations":[70510,73617,73661,76179,77314],"is_not":false,"summary":null,"term":"GO:0009228"},{"annotations":[77004],"is_not":false,"summary":null,"term":"GO:0009229"},{"annotations":[75307,76127],"is_not":false,"summary":null,"term":"GO:0009088"},{"annotations":[72006,76685],"is_not":false,"summary":null,"term":"GO:0006567"},{"annotations":[71093,73435],"is_not":false,"summary":null,"term":"GO:0006435"},{"annotations":[76019,76579],"is_not":false,"summary":null,"term":"GO:0038203"},{"annotations":[77440],"is_not":false,"summary":null,"term":"GO:0006360"},{"annotations":[74733,75668],"is_not":false,"summary":null,"term":"GO:0006366"},{"annotations":[76735],"is_not":false,"summary":null,"term":"GO:0006362"},{"annotations":[71652,72302,77901],"is_not":false,"summary":null,"term":"GO:0006361"},{"annotations":[72625,75474,77616,77744,78756,78900],"is_not":false,"summary":null,"term":"GO:0006367"},{"annotations":[71264,73475,78413],"is_not":false,"summary":null,"term":"GO:0006384"},{"annotations":[70243],"is_not":false,"summary":null,"term":"GO:0001113"},{"annotations":[71869,77743],"is_not":false,"summary":null,"term":"GO:0006283"},{"annotations":[73234,74547,75830,78842],"is_not":false,"summary":null,"term":"GO:0000972"},{"annotations":[70641],"is_not":false,"summary":null,"term":"GO:0045056"},{"annotations":[73249,74561],"is_not":false,"summary":null,"term":"GO:0002188"},{"annotations":[71741],"is_not":false,"summary":null,"term":"GO:0006413"},{"annotations":[76752],"is_not":false,"summary":null,"term":"GO:0006415"},{"annotations":[70138,71180,74053,76366,78149,78686],"is_not":false,"summary":null,"term":"GO:0055085"},{"annotations":[70747,74720,78091],"is_not":false,"summary":null,"term":"GO:0019346"},{"annotations":[73592,74014,75264,77776,78046,78497],"is_not":false,"summary":null,"term":"GO:0005992"},{"annotations":[71481],"is_not":false,"summary":null,"term":"GO:0005993"},{"annotations":[73589,74012,75262,77774,78044,78494],"is_not":false,"summary":null,"term":"GO:0070413"},{"annotations":[70545,70828,70884,71777,72928,73800,73936,74919,75111,78010],"is_not":false,"summary":null,"term":"GO:0006099"},{"annotations":[74112,76068],"is_not":false,"summary":null,"term":"GO:0019432"},{"annotations":[71487],"is_not":false,"summary":null,"term":"GO:0019433"},{"annotations":[70440,74428],"is_not":false,"summary":null,"term":"GO:0001680"},{"annotations":[71276],"is_not":false,"summary":null,"term":"GO:0001682"},{"annotations":[74051],"is_not":false,"summary":null,"term":"GO:0002943"},{"annotations":[72018,77389],"is_not":false,"summary":null,"term":"GO:0006409"},{"annotations":[72137,72470,73417,73572,74696,74835,75221,75409],"is_not":false,"summary":null,"term":"GO:0030488"},{"annotations":[71109],"is_not":false,"summary":null,"term":"GO:0006400"},{"annotations":[77028],"is_not":false,"summary":null,"term":"GO:0002939"},{"annotations":[72961],"is_not":false,"summary":null,"term":"GO:0002940"},{"annotations":[71377,71575],"is_not":false,"summary":null,"term":"GO:0008033"},{"annotations":[72703,75064,77344],"is_not":false,"summary":null,"term":"GO:0031119"},{"annotations":[78277],"is_not":false,"summary":null,"term":"GO:0071528"},{"annotations":[73385,73442],"is_not":false,"summary":null,"term":"GO:0006388"},{"annotations":[74749,75669,76037,78272],"is_not":false,"summary":null,"term":"GO:0042797"},{"annotations":[72179,78317],"is_not":false,"summary":null,"term":"GO:0002926"},{"annotations":[73613,74026,76422],"is_not":false,"summary":null,"term":"GO:0002143"},{"annotations":[72664,73715],"is_not":false,"summary":null,"term":"GO:0101030"},{"annotations":[71584,72608,73584,77719],"is_not":false,"summary":null,"term":"GO:0000379"},{"annotations":[71319,72855,73246,73703,76241,78128],"is_not":false,"summary":null,"term":"GO:0000162"},{"annotations":[70380],"is_not":false,"summary":null,"term":"GO:0006436"},{"annotations":[71021],"is_not":false,"summary":null,"term":"GO:0007021"},{"annotations":[75753],"is_not":false,"summary":null,"term":"GO:0006571"},{"annotations":[77517],"is_not":false,"summary":null,"term":"GO:0006437"},{"annotations":[71499,71790,72353],"is_not":false,"summary":null,"term":"GO:0034473"},{"annotations":[71500,71791,72354,72982,73375,74039,74498,75395,75955,76515],"is_not":false,"summary":null,"term":"GO:0034475"},{"annotations":[71501,71792,72355],"is_not":false,"summary":null,"term":"GO:0034476"},{"annotations":[78182],"is_not":false,"summary":null,"term":"GO:0034477"},{"annotations":[72757,73494,73655,73726,77393],"is_not":false,"summary":null,"term":"GO:0006744"},{"annotations":[71914],"is_not":false,"summary":null,"term":"GO:0010992"},{"annotations":[77359,77905,78225],"is_not":false,"summary":null,"term":"GO:0070086"},{"annotations":[71669,71874,73552,75501],"is_not":false,"summary":null,"term":"GO:0006511"},{"annotations":[73825],"is_not":false,"summary":null,"term":"GO:0071596"},{"annotations":[78867],"is_not":false,"summary":null,"term":"GO:0006225"},{"annotations":[75517],"is_not":false,"summary":null,"term":"GO:0006256"},{"annotations":[75269],"is_not":false,"summary":null,"term":"GO:0072334"},{"annotations":[70834,71036,72147,75879],"is_not":false,"summary":null,"term":"GO:0006048"},{"annotations":[70457,74613],"is_not":false,"summary":null,"term":"GO:0006636"},{"annotations":[73238],"is_not":false,"summary":null,"term":"GO:0019628"},{"annotations":[70847],"is_not":false,"summary":null,"term":"GO:0000050"},{"annotations":[74333],"is_not":false,"summary":null,"term":"GO:0006780"},{"annotations":[71336,71834],"is_not":false,"summary":null,"term":"GO:0006228"},{"annotations":[70215],"is_not":false,"summary":null,"term":"GO:0070914"},{"annotations":[71178,72650,72798,73770,77423,78668],"is_not":false,"summary":null,"term":"GO:0007035"},{"annotations":[72387,75825],"is_not":false,"summary":null,"term":"GO:0006624"},{"annotations":[73207],"is_not":false,"summary":null,"term":"GO:0034486"},{"annotations":[71177,71956,76481,77416],"is_not":false,"summary":null,"term":"GO:0007034"},{"annotations":[77414],"is_not":false,"summary":null,"term":"GO:0042144"},{"annotations":[73051],"is_not":false,"summary":null,"term":"GO:0007033"},{"annotations":[75557,76126,78433],"is_not":false,"summary":null,"term":"GO:0009099"},{"annotations":[72775],"is_not":false,"summary":null,"term":"GO:0006574"},{"annotations":[72482,73305,76729],"is_not":false,"summary":null,"term":"GO:0042761"},{"annotations":[70194,73407,75582,77984],"is_not":false,"summary":null,"term":"GO:0006900"},{"annotations":[72028,76595],"is_not":false,"summary":null,"term":"GO:0048278"},{"annotations":[70106,71552],"is_not":false,"summary":null,"term":"GO:0006904"},{"annotations":[72035,75732,76600,77024],"is_not":false,"summary":null,"term":"GO:0006906"},{"annotations":[73531,75414,76628],"is_not":false,"summary":null,"term":"GO:0048280"},{"annotations":[70289,71070,73929,75797,78200],"is_not":false,"summary":null,"term":"GO:0030050"},{"annotations":[72012,75429,75960,77367,78281],"is_not":false,"summary":null,"term":"GO:0016192"},{"annotations":[72138,73418,74254],"is_not":false,"summary":null,"term":"GO:0031591"},{"annotations":[78545],"is_not":false,"summary":null,"term":"GO:0042906"},{"annotations":[74758],"is_not":false,"summary":null,"term":"GO:0032265"},{"annotations":[74148],"is_not":false,"summary":null,"term":"GO:1904257"},{"annotations":[77189],"is_not":false,"summary":null,"term":"GO:0071577"}],"cellular_component":[{"annotations":[76812],"is_not":false,"summary":null,"term":"GO:0005945"},{"annotations":[70591,71105,71921,72629,73280,75122,75299,75645,76904],"is_not":false,"summary":null,"term":"GO:0030686"},{"annotations":[74999,75555],"is_not":false,"summary":null,"term":"GO:0005948"},{"annotations":[74029,74311,74663,75545,75837,76058,77988,78024,78204,78370,78632,78679],"is_not":false,"summary":null,"term":"GO:0030479"},{"annotations":[71588,75042],"is_not":false,"summary":null,"term":"GO:0005884"},{"annotations":[71589,76249],"is_not":false,"summary":null,"term":"GO:0032432"},{"annotations":[70619,72698,74654],"is_not":false,"summary":null,"term":"GO:0005658"},{"annotations":[73588,74011,75261,77773,78043,78493],"is_not":false,"summary":null,"term":"GO:0005946"},{"annotations":[70822,75981,77257],"is_not":false,"summary":null,"term":"GO:0017101"},{"annotations":[71882],"is_not":false,"summary":null,"term":"GO:0031250"},{"annotations":[70334,70744,72831,72914,75725,76690,77760,77837,77880,78556,78820],"is_not":false,"summary":null,"term":"GO:0005680"},{"annotations":[76551],"is_not":false,"summary":null,"term":"GO:0030121"},{"annotations":[73820,77185],"is_not":false,"summary":null,"term":"GO:0030122"},{"annotations":[76976],"is_not":false,"summary":null,"term":"GO:0030123"},{"annotations":[74310,75676,76778,77156,77683,78369,78498],"is_not":false,"summary":null,"term":"GO:0005885"},{"annotations":[72165,72471,78346],"is_not":false,"summary":null,"term":"GO:1990316"},{"annotations":[72288,72804],"is_not":false,"summary":null,"term":"GO:0034274"},{"annotations":[72565,76169,78155],"is_not":false,"summary":null,"term":"GO:0005776"},{"annotations":[71098,73081,74861],"is_not":false,"summary":null,"term":"GO:0031428"},{"annotations":[74056,78826],"is_not":false,"summary":null,"term":"GO:0031429"},{"annotations":[71421,73585],"is_not":false,"summary":null,"term":"GO:0005953"},{"annotations":[72822,78262],"is_not":false,"summary":null,"term":"GO:0005955"},{"annotations":[71039,73159],"is_not":false,"summary":null,"term":"GO:0005952"},{"annotations":[70538],"is_not":false,"summary":null,"term":"GO:0005951"},{"annotations":[70130,70557,70588,70682,70775,71878,71952,72150,72210,72306,72897,73546,73626,73631,74753,74937,74996,75104,75454,75959,76080,76322,77061,77227,77555,77621,77950,78116],"is_not":false,"summary":null,"term":"GO:0071013"},{"annotations":[70418,70689,74966],"is_not":false,"summary":null,"term":"GO:0016602"},{"annotations":[70500,73816,74090],"is_not":false,"summary":null,"term":"GO:0030015"},{"annotations":[71166,72408,75609],"is_not":false,"summary":null,"term":"GO:0016593"},{"annotations":[78612],"is_not":false,"summary":null,"term":"GO:0005938"},{"annotations":[70397],"is_not":false,"summary":null,"term":"GO:1902716"},{"annotations":[74741,77824],"is_not":false,"summary":null,"term":"GO:0032153"},{"annotations":[73777],"is_not":false,"summary":null,"term":"GO:0071944"},{"annotations":[70640,70711,71339,72950,73786,75541,76007,76800,78796],"is_not":false,"summary":null,"term":"GO:0009986"},{"annotations":[70111,72520,73390,75385,75812,76922,77237,78403],"is_not":false,"summary":null,"term":"GO:0005832"},{"annotations":[72758,77734],"is_not":false,"summary":null,"term":"GO:0030896"},{"annotations":[70562],"is_not":false,"summary":null,"term":"GO:0008623"},{"annotations":[70188,70306,70462,70621,73872,75193,76989,77458,77624,78905],"is_not":false,"summary":null,"term":"GO:0000785"},{"annotations":[70934],"is_not":false,"summary":null,"term":"GO:0034506"},{"annotations":[71675,78086],"is_not":false,"summary":null,"term":"GO:0097361"},{"annotations":[74463,78250],"is_not":false,"summary":null,"term":"GO:0005801"},{"annotations":[77714],"is_not":false,"summary":null,"term":"GO:0033106"},{"annotations":[75836],"is_not":false,"summary":null,"term":"GO:0071439"},{"annotations":[73456,78363],"is_not":false,"summary":null,"term":"GO:0030125"},{"annotations":[73405],"is_not":false,"summary":null,"term":"GO:0005905"},{"annotations":[73406],"is_not":false,"summary":null,"term":"GO:0030136"},{"annotations":[72109,76072,77942,78130],"is_not":false,"summary":null,"term":"GO:0000243"},{"annotations":[70782],"is_not":false,"summary":null,"term":"GO:0000793"},{"annotations":[74584,74979],"is_not":false,"summary":null,"term":"GO:0000794"},{"annotations":[71880,75373],"is_not":false,"summary":null,"term":"GO:0008180"},{"annotations":[71114,73250,76892,77120,78466],"is_not":false,"summary":null,"term":"GO:0030126"},{"annotations":[71466,71519,72890,74175,74528,74907,75482,75869,77301],"is_not":false,"summary":null,"term":"GO:0030127"},{"annotations":[70170,71214,72271,73999,74216,74922,74971,76063,76174,77506],"is_not":false,"summary":null,"term":"GO:0030134"},{"annotations":[70109,73741,74269,75234,76451,76740,77222],"is_not":false,"summary":null,"term":"GO:0070847"},{"annotations":[70530,70536,71964,76044],"is_not":false,"summary":null,"term":"GO:0032541"},{"annotations":[78029],"is_not":false,"summary":null,"term":"GO:0070692"},{"annotations":[72509,76208,76843],"is_not":false,"summary":null,"term":"GO:0031390"},{"annotations":[74386],"is_not":false,"summary":null,"term":"GO:0031463"},{"annotations":[71061,75356],"is_not":false,"summary":null,"term":"GO:0080008"},{"annotations":[75595,78032,78050],"is_not":false,"summary":null,"term":"GO:0035361"},{"annotations":[74261,77386],"is_not":false,"summary":null,"term":"GO:0032545"},{"annotations":[70371,70789,71528,73758,74442,75764,77105],"is_not":false,"summary":null,"term":"GO:0000307"},{"annotations":[74484],"is_not":false,"summary":null,"term":"GO:0097268"},{"annotations":[70448,70497,70549,70722,70748,70821,70977,70982,71280,71369,71432,71572,71603,71685,71690,71913,71928,72070,72079,72141,72186,72196,72316,72333,72576,72710,72832,72997,73077,73509,73515,73530,73788,73826,73829,73832,74050,74199,74357,74444,74637,74772,74789,74847,74898,75088,75272,75275,75311,75486,75495,75629,75683,75766,75914,75945,76583,76712,76746,76871,76993,77013,77107,77218,77284,77628,77641,77779,77852,77957,77977,77992,78121,78209,78257,78464,78599,78699],"is_not":false,"summary":null,"term":"GO:0005737"},{"annotations":[76351,78339],"is_not":false,"summary":null,"term":"GO:0005868"},{"annotations":[71493,71784,72347,72976,74033,74144,74492,75389,76509],"is_not":false,"summary":null,"term":"GO:0000177"},{"annotations":[75690],"is_not":false,"summary":null,"term":"GO:0005881"},{"annotations":[75580],"is_not":false,"summary":null,"term":"GO:0009898"},{"annotations":[70738,72724,73675,74302,75875,78105],"is_not":false,"summary":null,"term":"GO:0010494"},{"annotations":[74150,74887],"is_not":false,"summary":null,"term":"GO:0031410"},{"annotations":[70141,70146,70165,70177,70184,70230,70329,70338,70359,70404,70442,70511,70521,70528,70578,70636,70671,70743,70760,70767,70809,70854,70905,70913,70986,71004,71042,71153,71231,71237,71243,71282,71314,71334,71344,71412,71456,71639,71656,71696,71709,71736,71740,71806,71832,71847,71961,71985,71989,72004,72038,72047,72083,72095,72128,72131,72178,72191,72336,72394,72458,72473,72566,72581,72628,72654,72668,72697,72771,72841,72927,73024,73090,73103,73128,73134,73160,73176,73185,73292,73309,73352,73368,73445,73463,73481,73491,73527,73565,73603,73607,73618,73637,73646,73653,73662,73709,73774,73874,73902,73916,74016,74019,74060,74110,74134,74184,74207,74242,74246,74282,74295,74308,74329,74367,74383,74400,74450,74577,74616,74625,74641,74652,74672,74715,74824,74843,74876,74927,74989,75047,75051,75059,75085,75097,75128,75174,75212,75228,75310,75401,75408,75447,75528,75538,75593,75636,75686,75705,75719,75735,75771,75820,75851,75889,75901,75982,76015,76093,76095,76136,76142,76152,76196,76240,76267,76309,76312,76336,76409,76500,76519,76577,76589,76618,76647,76769,76772,76881,76935,76945,76960,77075,77172,77192,77258,77315,77321,77361,77378,77395,77401,77410,77418,77446,77456,77470,77472,77520,77528,77536,77560,77660,77696,77710,77713,77748,77787,77793,77813,77818,77827,77833,77845,77907,77930,77956,77968,78040,78061,78067,78081,78114,78156,78186,78227,78238,78253,78284,78291,78296,78329,78421,78527,78549,78585,78592,78641,78810,78832,78845,78861,78871,78916],"is_not":false,"summary":null,"term":"GO:0005829"},{"annotations":[70348,70446,70476,70488,70503,70583,71200,71261,71402,71615,71773,71925,72002,72025,72099,72182,72285,72748,73058,73131,73140,73154,73228,73288,73751,73785,73877,73888,73891,73913,73950,74181,74213,74471,74477,74693,74856,75004,75083,75327,75563,75699,75833,75918,75938,76053,76444,76614,76914,76956,77161,77164,77184,77290,77662,77861,78417,78517,78521,78898],"is_not":false,"summary":null,"term":"GO:0022625"},{"annotations":[70282,70318,70629,71028,71287,71297,71839,72646,73194,73326,73438,73521,73977,73992,74095,74141,74272,74403,74619,74644,75217,75745,76220,76761,77292,77297,77464,77800,78708],"is_not":false,"summary":null,"term":"GO:0022627"},{"annotations":[76421],"is_not":false,"summary":null,"term":"GO:0002144"},{"annotations":[74516,75524,78183],"is_not":false,"summary":null,"term":"GO:0042729"},{"annotations":[74951],"is_not":false,"summary":null,"term":"GO:0031431"},{"annotations":[71947,74004],"is_not":false,"summary":null,"term":"GO:1904423"},{"annotations":[71094,74592,76000],"is_not":false,"summary":null,"term":"GO:0043625"},{"annotations":[70480,71653],"is_not":false,"summary":null,"term":"GO:0000935"},{"annotations":[78817],"is_not":false,"summary":null,"term":"GO:0032807"},{"annotations":[71893,76147],"is_not":false,"summary":null,"term":"GO:0031261"},{"annotations":[71277],"is_not":false,"summary":null,"term":"GO:0044695"},{"annotations":[72738,74228,78666],"is_not":false,"summary":null,"term":"GO:0005769"},{"annotations":[70603],"is_not":false,"summary":null,"term":"GO:0032126"},{"annotations":[70121,71607,76328],"is_not":false,"summary":null,"term":"GO:0036286"},{"annotations":[71537,78293],"is_not":false,"summary":null,"term":"GO:0000408"},{"annotations":[72510,76209,76844],"is_not":false,"summary":null,"term":"GO:0031391"},{"annotations":[72093,72177,78314],"is_not":false,"summary":null,"term":"GO:0033588"},{"annotations":[71959,74122,75159,76088,77304,78731],"is_not":false,"summary":null,"term":"GO:0072546"},{"annotations":[75245,77193],"is_not":false,"summary":null,"term":"GO:0030139"},{"annotations":[70245,70515,70644,71278,71488,71905,72268,72378,72675,72734,72919,73749,73996,74006,74163,74970,75434,75560,75758,75852,76060,76292,76955,77122,77338,77503,77571,77630,77912],"is_not":false,"summary":null,"term":"GO:0005783"},{"annotations":[77384],"is_not":false,"summary":null,"term":"GO:0034663"},{"annotations":[71470,71520,74176,74529,74908,75483,75870,77302],"is_not":false,"summary":null,"term":"GO:0070971"},{"annotations":[77770,78683],"is_not":false,"summary":null,"term":"GO:0005788"},{"annotations":[70150,70168,70298,70599,71064,71119,71225,71326,71700,71843,71889,71949,72416,72742,73183,73415,73535,74125,74215,74323,74375,74611,74914,75118,75364,75418,75438,75628,75966,76069,76190,76238,77017,77155,77205,77479,77573,78483,78675,78743],"is_not":false,"summary":null,"term":"GO:0005789"},{"annotations":[74255],"is_not":false,"summary":null,"term":"GO:0031211"},{"annotations":[70169,70832,72269,73536,73997,76061,77123,77504],"is_not":false,"summary":null,"term":"GO:0005793"},{"annotations":[76045],"is_not":false,"summary":null,"term":"GO:0140268"},{"annotations":[70713,71395,71550,71975,73337,73458,74614,75074,75650,76563,76625,77255,77883,78344,78365],"is_not":false,"summary":null,"term":"GO:0005768"},{"annotations":[72431,76977,78695],"is_not":false,"summary":null,"term":"GO:0010008"},{"annotations":[70646,73537,75420],"is_not":false,"summary":null,"term":"GO:0012507"},{"annotations":[77639],"is_not":false,"summary":null,"term":"GO:0035657"},{"annotations":[70262,78522],"is_not":false,"summary":null,"term":"GO:0032865"},{"annotations":[72313],"is_not":false,"summary":null,"term":"GO:0000813"},{"annotations":[70978,72211,77310],"is_not":false,"summary":null,"term":"GO:0000814"},{"annotations":[70191,71249,75167,75578,76525],"is_not":false,"summary":null,"term":"GO:0000815"},{"annotations":[73108],"is_not":false,"summary":null,"term":"GO:0033565"},{"annotations":[73987],"is_not":false,"summary":null,"term":"GO:0016282"},{"annotations":[71556,76888],"is_not":false,"summary":null,"term":"GO:0005850"},{"annotations":[72120,73558],"is_not":false,"summary":null,"term":"GO:0005851"},{"annotations":[74558],"is_not":false,"summary":null,"term":"GO:0071540"},{"annotations":[73908,74559,75011],"is_not":false,"summary":null,"term":"GO:0071541"},{"annotations":[72414,73722,74203],"is_not":false,"summary":null,"term":"GO:0016281"},{"annotations":[70941,75287,76546],"is_not":false,"summary":null,"term":"GO:0000145"},{"annotations":[72123,76397],"is_not":false,"summary":null,"term":"GO:0034044"},{"annotations":[70804,78655],"is_not":false,"summary":null,"term":"GO:0035145"},{"annotations":[70638,70709,72948,76005,76798,77271],"is_not":false,"summary":null,"term":"GO:0005576"},{"annotations":[71848,73369,73639,74777,78550],"is_not":false,"summary":null,"term":"GO:0019898"},{"annotations":[77985,78677],"is_not":false,"summary":null,"term":"GO:0008290"},{"annotations":[76491],"is_not":false,"summary":null,"term":"GO:0035101"},{"annotations":[74172],"is_not":false,"summary":null,"term":"GO:0090443"},{"annotations":[71128,72144],"is_not":false,"summary":null,"term":"GO:0005835"},{"annotations":[71338,72233,72935,73118,75540,76087,76799],"is_not":false,"summary":null,"term":"GO:0009277"},{"annotations":[70325,70683,70813,72013,72175,72537,73394,73598,74607,74648,75498,75927,77352,78083,78544,78734],"is_not":false,"summary":null,"term":"GO:0000324"},{"annotations":[70687],"is_not":false,"summary":null,"term":"GO:0000328"},{"annotations":[70454,70609,70741,70944,71176,72077,72202,72422,72430,72797,72815,72884,73367,73769,74041,74248,74369,74744,75312,75649,77325,77413,77863,77891,78298,78378,78548,78665,78694,78896],"is_not":false,"summary":null,"term":"GO:0000329"},{"annotations":[70162,77500,78356],"is_not":false,"summary":null,"term":"GO:0000938"},{"annotations":[73319],"is_not":false,"summary":null,"term":"GO:1990130"},{"annotations":[74839],"is_not":false,"summary":null,"term":"GO:0061700"},{"annotations":[72656,74602],"is_not":false,"summary":null,"term":"GO:0043529"},{"annotations":[76372,77804,78792],"is_not":false,"summary":null,"term":"GO:0034657"},{"annotations":[70574,77962,78566,78798],"is_not":false,"summary":null,"term":"GO:0000811"},{"annotations":[76116,77275],"is_not":false,"summary":null,"term":"GO:0017177"},{"annotations":[76465,77565],"is_not":false,"summary":null,"term":"GO:0017109"},{"annotations":[77318],"is_not":false,"summary":null,"term":"GO:1903600"},{"annotations":[71857,74537],"is_not":false,"summary":null,"term":"GO:0030956"},{"annotations":[73667],"is_not":false,"summary":null,"term":"GO:0005960"},{"annotations":[76503],"is_not":false,"summary":null,"term":"GO:1990529"},{"annotations":[71179,76359],"is_not":false,"summary":null,"term":"GO:0000506"},{"annotations":[70726,70757,70833,70840,71151,71190,71658,71667,71937,72270,72379,72384,72598,72676,73650,73981,73998,74164,74519,75515,75748,75853,76062,76676,77505],"is_not":false,"summary":null,"term":"GO:0005794"},{"annotations":[74968],"is_not":false,"summary":null,"term":"GO:0000137"},{"annotations":[76619],"is_not":false,"summary":null,"term":"GO:0031985"},{"annotations":[71408,75643,77466],"is_not":false,"summary":null,"term":"GO:0005797"},{"annotations":[71288,71631,71714,73534,74813,74969,75096,75432,76021,76262,77121,77334,77709,77755,78514],"is_not":false,"summary":null,"term":"GO:0000139"},{"annotations":[70645],"is_not":false,"summary":null,"term":"GO:0005795"},{"annotations":[78779],"is_not":false,"summary":null,"term":"GO:0070319"},{"annotations":[71407,75642,77465],"is_not":false,"summary":null,"term":"GO:0000138"},{"annotations":[70604,74904,76367],"is_not":false,"summary":null,"term":"GO:0017119"},{"annotations":[71096,74088,74098],"is_not":false,"summary":null,"term":"GO:0042765"},{"annotations":[74742],"is_not":false,"summary":null,"term":"GO:0035838"},{"annotations":[73559],"is_not":false,"summary":null,"term":"GO:0032045"},{"annotations":[76861],"is_not":false,"summary":null,"term":"GO:0033573"},{"annotations":[73299],"is_not":false,"summary":null,"term":"GO:0000417"},{"annotations":[73893,77915],"is_not":false,"summary":null,"term":"GO:0048476"},{"annotations":[71322,71482,74218],"is_not":false,"summary":null,"term":"GO:0033503"},{"annotations":[76242],"is_not":false,"summary":null,"term":"GO:0031942"},{"annotations":[70220,72215,72483],"is_not":false,"summary":null,"term":"GO:0031011"},{"annotations":[73330,75439],"is_not":false,"summary":null,"term":"GO:0070916"},{"annotations":[76821],"is_not":false,"summary":null,"term":"GO:1990604"},{"annotations":[73501,75282],"is_not":false,"summary":null,"term":"GO:0005871"},{"annotations":[70801,72679,75488,77990],"is_not":false,"summary":null,"term":"GO:0000776"},{"annotations":[70611,77058],"is_not":false,"summary":null,"term":"GO:0043564"},{"annotations":[76049],"is_not":false,"summary":null,"term":"GO:1990221"},{"annotations":[71077,71450,71563,74229,76157,76276,78480,78667],"is_not":false,"summary":null,"term":"GO:0005770"},{"annotations":[75421,77311],"is_not":false,"summary":null,"term":"GO:0031902"},{"annotations":[71120,71489,73649,73718,74007,76293,77631],"is_not":false,"summary":null,"term":"GO:0005811"},{"annotations":[71048,75033,77556,77622],"is_not":false,"summary":null,"term":"GO:1990726"},{"annotations":[70237],"is_not":false,"summary":null,"term":"GO:0000136"},{"annotations":[70484,72267,73702,76663],"is_not":false,"summary":null,"term":"GO:0043332"},{"annotations":[71577],"is_not":false,"summary":null,"term":"GO:0031934"},{"annotations":[75076,76413,76468],"is_not":false,"summary":null,"term":"GO:0030907"},{"annotations":[70247,71161,73032,73312,74155,76402],"is_not":false,"summary":null,"term":"GO:0042555"},{"annotations":[72266,73701],"is_not":false,"summary":null,"term":"GO:0031097"},{"annotations":[70108,73349,73740,74268,75233,76450,76739,77221,77856],"is_not":false,"summary":null,"term":"GO:0016592"},{"annotations":[70135,70415,70529,70727,71005,71181,71409,71630,71659,71955,72039,72331,72819,73278,73510,74550,74570,74578,74827,75516,75644,76177,77168,77467,77522,77884,78215,78660],"is_not":false,"summary":null,"term":"GO:0016020"},{"annotations":[70433,78728],"is_not":false,"summary":null,"term":"GO:0017102"},{"annotations":[74534],"is_not":false,"summary":null,"term":"GO:0061617"},{"annotations":[77780],"is_not":false,"summary":null,"term":"GO:0005874"},{"annotations":[71134,72497,72587,74209,74339,75182,76269,76786],"is_not":false,"summary":null,"term":"GO:0015630"},{"annotations":[70935],"is_not":false,"summary":null,"term":"GO:0034992"},{"annotations":[78613],"is_not":false,"summary":null,"term":"GO:0035371"},{"annotations":[74536],"is_not":false,"summary":null,"term":"GO:0044284"},{"annotations":[70896],"is_not":false,"summary":null,"term":"GO:0045025"},{"annotations":[76456],"is_not":false,"summary":null,"term":"GO:0034245"},{"annotations":[78026,78400],"is_not":false,"summary":null,"term":"GO:0005740"},{"annotations":[70303,70703,70971,71353,72075,73493,74251,74987,75294,76385,76464,76535,76839,77198,78596,78647,78669],"is_not":false,"summary":null,"term":"GO:0005743"},{"annotations":[75947,78564],"is_not":false,"summary":null,"term":"GO:0042720"},{"annotations":[70400,75313,75978,76056,77006,77249,77511],"is_not":false,"summary":null,"term":"GO:0005758"},{"annotations":[70992,71268,71946,72067,72368,72694,72870,74224,74708,74941,75768,75792,76287,76826,77047,77078,77287,77926,77980,78235,78453,78914],"is_not":false,"summary":null,"term":"GO:0005762"},{"annotations":[70393,70910,71439,71600,72219,73935,74021,74074,75842,76732,76950,77027,77045,77055,77114,77245,77920,78570],"is_not":false,"summary":null,"term":"GO:0005759"},{"annotations":[75001],"is_not":false,"summary":null,"term":"GO:0042645"},{"annotations":[71007,71623,72735,74380],"is_not":false,"summary":null,"term":"GO:0005741"},{"annotations":[70665],"is_not":false,"summary":null,"term":"GO:0005742"},{"annotations":[70208],"is_not":false,"summary":null,"term":"GO:0000276"},{"annotations":[72617],"is_not":false,"summary":null,"term":"GO:0005754"},{"annotations":[77953],"is_not":false,"summary":null,"term":"GO:0000274"},{"annotations":[72452,73156,74160],"is_not":false,"summary":null,"term":"GO:0005967"},{"annotations":[74102,75223],"is_not":false,"summary":null,"term":"GO:0005749"},{"annotations":[74963],"is_not":false,"summary":null,"term":"GO:0005750"},{"annotations":[72040,73753],"is_not":false,"summary":null,"term":"GO:0005751"},{"annotations":[72391,72546,73003,73802,73851,75141,75722,77197],"is_not":false,"summary":null,"term":"GO:0005763"},{"annotations":[70118,70207,70408,70425,70520,70882,70889,70929,70946,70950,71108,71141,71541,71637,71775,71798,71804,71970,72190,72446,72464,72486,72705,72722,72792,72817,72931,72959,73027,73270,73430,74101,74235,74287,74553,74771,74807,74837,74917,75014,75092,75214,75296,75378,75400,75521,75784,75811,75922,76041,76099,76124,76362,76499,76524,77003,77088,77147,77180,77348,77844,78009,78079,78237,78328,78505,78608],"is_not":false,"summary":null,"term":"GO:0005739"},{"annotations":[72681,73622,74949],"is_not":false,"summary":null,"term":"GO:0072686"},{"annotations":[73505,77677],"is_not":false,"summary":null,"term":"GO:0061673"},{"annotations":[73504,75691,77676],"is_not":false,"summary":null,"term":"GO:1990023"},{"annotations":[70936,71164,74221],"is_not":false,"summary":null,"term":"GO:0044732"},{"annotations":[75257,77254,78770],"is_not":false,"summary":null,"term":"GO:0034457"},{"annotations":[78096],"is_not":false,"summary":null,"term":"GO:0030870"},{"annotations":[78192],"is_not":false,"summary":null,"term":"GO:0031533"},{"annotations":[70450],"is_not":false,"summary":null,"term":"GO:0005847"},{"annotations":[75500],"is_not":false,"summary":null,"term":"GO:1990304"},{"annotations":[74557],"is_not":false,"summary":null,"term":"GO:0043614"},{"annotations":[70192,71251,75169,75254,75579,77982],"is_not":false,"summary":null,"term":"GO:0005771"},{"annotations":[70901],"is_not":false,"summary":null,"term":"GO:0032389"},{"annotations":[72688],"is_not":false,"summary":null,"term":"GO:0032301"},{"annotations":[73619],"is_not":false,"summary":null,"term":"GO:1990811"},{"annotations":[71744,72461,78571],"is_not":false,"summary":null,"term":"GO:0016460"},{"annotations":[75850],"is_not":false,"summary":null,"term":"GO:0005854"},{"annotations":[70394,75236,76494],"is_not":false,"summary":null,"term":"GO:0031415"},{"annotations":[70899,76858],"is_not":false,"summary":null,"term":"GO:0031416"},{"annotations":[72245],"is_not":false,"summary":null,"term":"GO:0031417"},{"annotations":[74460,75163,75191,76182],"is_not":false,"summary":null,"term":"GO:0031262"},{"annotations":[72498,78736],"is_not":false,"summary":null,"term":"GO:0030690"},{"annotations":[72499,78737],"is_not":false,"summary":null,"term":"GO:0030691"},{"annotations":[72441,77588],"is_not":false,"summary":null,"term":"GO:0030692"},{"annotations":[72787,73381,73467,75320,76701,77653,78746],"is_not":false,"summary":null,"term":"GO:0035267"},{"annotations":[73862,73971],"is_not":false,"summary":null,"term":"GO:0016604"},{"annotations":[70697],"is_not":false,"summary":null,"term":"GO:0005846"},{"annotations":[78136],"is_not":false,"summary":null,"term":"GO:0000228"},{"annotations":[72507,75509,76206,76841],"is_not":false,"summary":null,"term":"GO:0043599"},{"annotations":[70181,70358,71455,71638,72680,75084,77400],"is_not":false,"summary":null,"term":"GO:0005635"},{"annotations":[70870,71492,71783,72346,72975,73225,74032,74143,74491,75388,76508],"is_not":false,"summary":null,"term":"GO:0000176"},{"annotations":[70933],"is_not":false,"summary":null,"term":"GO:0005637"},{"annotations":[78279],"is_not":false,"summary":null,"term":"GO:0016363"},{"annotations":[75710],"is_not":false,"summary":null,"term":"GO:0031965"},{"annotations":[75334],"is_not":false,"summary":null,"term":"GO:1990862"},{"annotations":[70300,74275,77577],"is_not":false,"summary":null,"term":"GO:0005664"},{"annotations":[77913],"is_not":false,"summary":null,"term":"GO:0042175"},{"annotations":[75341],"is_not":false,"summary":null,"term":"GO:0034399"},{"annotations":[70361,73966,74901,75827,77485,78276,78463],"is_not":false,"summary":null,"term":"GO:0005643"},{"annotations":[71143,76235,78712],"is_not":false,"summary":null,"term":"GO:0044613"},{"annotations":[75018],"is_not":false,"summary":null,"term":"GO:0044614"},{"annotations":[70750,74544,75470],"is_not":false,"summary":null,"term":"GO:0044611"},{"annotations":[71781,72683,72891,73231,73562,76925,78839],"is_not":false,"summary":null,"term":"GO:0031080"},{"annotations":[76394],"is_not":false,"summary":null,"term":"GO:0043596"},{"annotations":[70475],"is_not":false,"summary":null,"term":"GO:0031380"},{"annotations":[72114,78019],"is_not":false,"summary":null,"term":"GO:0016607"},{"annotations":[71376,71507],"is_not":false,"summary":null,"term":"GO:0005655"},{"annotations":[70235,70267,70506,70558,70593,70666,70700,70736,70807,70879,70920,71029,71106,71112,71362,71545,71592,71729,71922,72103,72249,72292,72406,72443,72502,72519,72529,72535,72636,72720,72777,72824,72847,72873,72879,72980,73162,73256,73324,73335,73512,73597,73780,73959,73993,74037,74166,74447,74627,74636,74687,74869,74885,74938,75340,75393,75450,75531,75647,75674,75925,76085,76130,76146,76229,76245,76304,76560,76762,76905,76930,77133,77137,77145,77279,77544,77586,77590,77753,77895,78120,78163,78185,78233,78361,78474,78580,78589,78740],"is_not":false,"summary":null,"term":"GO:0005730"},{"annotations":[72501,72709,72712,73357,73373,74417,75173,75953,77991,78093,78437,78739,78788],"is_not":false,"summary":null,"term":"GO:0005654"},{"annotations":[70383],"is_not":false,"summary":null,"term":"GO:0031588"},{"annotations":[70214,74394],"is_not":false,"summary":null,"term":"GO:0000110"},{"annotations":[72194,72574],"is_not":false,"summary":null,"term":"GO:0000111"},{"annotations":[70126,70154,70176,70189,70254,70274,70313,70337,70369,70372,70384,70395,70430,70464,70482,70491,70631,70654,70662,70673,70721,70759,70763,70784,70790,70818,70888,70904,70956,70959,70966,70981,71041,71053,71081,71088,71147,71169,71172,71187,71219,71281,71290,71309,71323,71356,71379,71410,71431,71440,71444,71513,71529,71535,71671,71684,71693,71725,71735,71753,71796,71868,71873,71911,71912,71957,71988,71998,72008,72043,72069,72087,72094,72117,72140,72162,72170,72185,72264,72344,72366,72372,72393,72402,72420,72425,72433,72439,72492,72504,72560,72614,72643,72653,72701,72715,72800,72810,72850,72864,72877,72885,72957,72965,73069,73076,73188,73205,73222,73258,73301,73361,73412,73441,73449,73451,73468,73479,73526,73549,73571,73580,73606,73645,73704,73806,73831,73865,73867,73894,73915,73919,73960,74066,74117,74193,74195,74198,74219,74253,74258,74276,74281,74290,74294,74328,74345,74353,74433,74443,74449,74487,74489,74506,74599,74605,74621,74657,74676,74683,74700,74702,74714,74732,74775,74794,74850,74875,74880,74926,74947,75087,75090,75115,75144,75147,75151,75194,75274,75279,75309,75355,75411,75425,75504,75537,75548,75570,75640,75658,75702,75704,75734,75788,75845,75859,75863,75867,75886,75893,75977,76014,76027,76150,76200,76253,76283,76314,76410,76428,76441,76565,76624,76633,76640,76667,76671,76686,76696,76707,76776,76805,76848,76932,76937,76966,77015,77049,77096,77106,77146,77231,77235,77243,77327,77341,77394,77397,77403,77409,77417,77430,77434,77443,77459,77478,77529,77534,77580,77594,77625,77627,77675,77690,77725,77747,77796,77816,77851,77867,77934,77998,78004,78015,78033,78037,78051,78069,78144,78165,78181,78220,78282,78285,78295,78304,78315,78320,78335,78340,78395,78407,78449,78457,78504,78577,78611,78629,78640,78644,78701,78786,78806,78809,78865,78874,78906],"is_not":false,"summary":null,"term":"GO:0005634"},{"annotations":[76277],"is_not":false,"summary":null,"term":"GO:0071561"},{"annotations":[73989,74787,77642,77928],"is_not":false,"summary":null,"term":"GO:0008250"},{"annotations":[70152,70501,70993,71761,72624,73818,73938,74091,75034,75206,75738,75874,76591,76832,77557,77702,77729,78074,78311,78334,78473],"is_not":false,"summary":null,"term":"GO:0000932"},{"annotations":[71184,73677,75975],"is_not":false,"summary":null,"term":"GO:0001405"},{"annotations":[77700],"is_not":false,"summary":null,"term":"GO:0031251"},{"annotations":[78693],"is_not":false,"summary":null,"term":"GO:0070772"},{"annotations":[71299],"is_not":false,"summary":null,"term":"GO:0043626"},{"annotations":[73387,74388,75348],"is_not":false,"summary":null,"term":"GO:0070545"},{"annotations":[71458,73092,74115],"is_not":false,"summary":null,"term":"GO:0097038"},{"annotations":[71668,72048,73904],"is_not":false,"summary":null,"term":"GO:0048471"},{"annotations":[70937,74828],"is_not":false,"summary":null,"term":"GO:1990429"},{"annotations":[70912],"is_not":false,"summary":null,"term":"GO:0005782"},{"annotations":[70939,71699,73127,73291,74797,76959],"is_not":false,"summary":null,"term":"GO:0005778"},{"annotations":[70426,71396,72238,73239,73924,75694,78410],"is_not":false,"summary":null,"term":"GO:0005777"},{"annotations":[71393,72472,77530],"is_not":false,"summary":null,"term":"GO:0000407"},{"annotations":[71849,72289,72568,72805,73370,78158,78348,78551],"is_not":false,"summary":null,"term":"GO:0034045"},{"annotations":[76585,77704],"is_not":false,"summary":null,"term":"GO:0009328"},{"annotations":[71391,75802,76272],"is_not":false,"summary":null,"term":"GO:0034271"},{"annotations":[71392,75803,76273],"is_not":false,"summary":null,"term":"GO:0034272"},{"annotations":[72554,73625,74993,76077,77947],"is_not":false,"summary":null,"term":"GO:0034715"},{"annotations":[70104,70123,70259,70326,70391,70478,70602,70681,70684,70779,70814,71016,71197,71457,71551,71609,71716,71816,71890,71938,72107,72142,72242,72254,72377,72380,72538,72707,72737,72752,72795,72887,72902,72939,72943,72974,72985,73091,73104,73199,73210,73459,73599,73710,73847,73903,74065,74078,74165,74230,74348,74364,74515,74596,74608,74649,74782,75499,75553,75652,75731,75908,75928,76043,76294,76330,76460,77022,77031,77131,77407,77474,77483,77632,77823,77908,78217,78228,78241,78366,78435,78442,78603,78631,78720,78735,78884],"is_not":false,"summary":null,"term":"GO:0005886"},{"annotations":[77102],"is_not":false,"summary":null,"term":"GO:1902929"},{"annotations":[70131,71942,72767,76789,76911,77332],"is_not":false,"summary":null,"term":"GO:0071014"},{"annotations":[72899],"is_not":false,"summary":null,"term":"GO:0071020"},{"annotations":[78303],"is_not":false,"summary":null,"term":"GO:0070761"},{"annotations":[70587,72556,73000,74422,74995,75252,75479,76079,76604,77554,77949,78762],"is_not":false,"summary":null,"term":"GO:0071011"},{"annotations":[70155,71018,75599,77362],"is_not":false,"summary":null,"term":"GO:0016272"},{"annotations":[71360,71591,72173,72291,74387,74632,75338,75347,75505,75854,76302,77543,77973,78184,78578],"is_not":false,"summary":null,"term":"GO:0030687"},{"annotations":[70174,70592,71343,73854,74293,74626,78118,78168],"is_not":false,"summary":null,"term":"GO:0030688"},{"annotations":[70125,72116,72392,72799,74604,74799,77208],"is_not":false,"summary":null,"term":"GO:0019773"},{"annotations":[72880,78406],"is_not":false,"summary":null,"term":"GO:0008540"},{"annotations":[71386,72652,73377,73697,73755,75565,76971,78268],"is_not":false,"summary":null,"term":"GO:0008541"},{"annotations":[72882,78408],"is_not":false,"summary":null,"term":"GO:0034515"},{"annotations":[71422,73339],"is_not":false,"summary":null,"term":"GO:0005965"},{"annotations":[73563],"is_not":false,"summary":null,"term":"GO:0005956"},{"annotations":[72711],"is_not":false,"summary":null,"term":"GO:0030289"},{"annotations":[71242,71682,75113,77224],"is_not":false,"summary":null,"term":"GO:0000159"},{"annotations":[77952],"is_not":false,"summary":null,"term":"GO:0045261"},{"annotations":[70129,71862,71940,72896,73052,76377,76852,76909],"is_not":false,"summary":null,"term":"GO:0000974"},{"annotations":[71384,71767,73020,75847,78374],"is_not":false,"summary":null,"term":"GO:0034388"},{"annotations":[73488,77605,78280],"is_not":false,"summary":null,"term":"GO:0005968"},{"annotations":[72508,76207,76842],"is_not":false,"summary":null,"term":"GO:0031389"},{"annotations":[77373],"is_not":false,"summary":null,"term":"GO:0033063"},{"annotations":[77374],"is_not":false,"summary":null,"term":"GO:0033065"},{"annotations":[72649],"is_not":false,"summary":null,"term":"GO:0043291"},{"annotations":[71578],"is_not":false,"summary":null,"term":"GO:0033553"},{"annotations":[71191,76391],"is_not":false,"summary":null,"term":"GO:0055037"},{"annotations":[77151,78765],"is_not":false,"summary":null,"term":"GO:0031298"},{"annotations":[78530],"is_not":false,"summary":null,"term":"GO:0070274"},{"annotations":[71974],"is_not":false,"summary":null,"term":"GO:0030904"},{"annotations":[70712],"is_not":false,"summary":null,"term":"GO:0030905"},{"annotations":[78834],"is_not":false,"summary":null,"term":"GO:0032299"},{"annotations":[71272,71506,73295,75329],"is_not":false,"summary":null,"term":"GO:0000172"},{"annotations":[72723,76141,77523,77695,77850,77910,78382,78860],"is_not":false,"summary":null,"term":"GO:1990904"},{"annotations":[75622],"is_not":false,"summary":null,"term":"GO:0005971"},{"annotations":[72396,73513],"is_not":false,"summary":null,"term":"GO:0002189"},{"annotations":[75095,76261],"is_not":false,"summary":null,"term":"GO:0034066"},{"annotations":[75605],"is_not":false,"summary":null,"term":"GO:0042565"},{"annotations":[70439,71211,73846,74123,74567,74956,75139,75161,75666,76034,76734],"is_not":false,"summary":null,"term":"GO:0005736"},{"annotations":[75132,78460],"is_not":false,"summary":null,"term":"GO:0070860"},{"annotations":[72301,77900],"is_not":false,"summary":null,"term":"GO:0000500"},{"annotations":[78724],"is_not":false,"summary":null,"term":"GO:0090575"},{"annotations":[71209,72621,72989,73995,74565,75056,75137,75664,76032,76947,77742],"is_not":false,"summary":null,"term":"GO:0005665"},{"annotations":[70438,71210,71263,71448,73047,73845,74455,74566,74748,75138,75665,75835,76033,78271,78412],"is_not":false,"summary":null,"term":"GO:0005666"},{"annotations":[75290,76341],"is_not":false,"summary":null,"term":"GO:0033698"},{"annotations":[74358,76342,77069,77497],"is_not":false,"summary":null,"term":"GO:0070210"},{"annotations":[72609,72786,75741],"is_not":false,"summary":null,"term":"GO:0032221"},{"annotations":[70115,73064,75769],"is_not":false,"summary":null,"term":"GO:1990112"},{"annotations":[73433,78177,78391],"is_not":false,"summary":null,"term":"GO:0016586"},{"annotations":[72265,73700],"is_not":false,"summary":null,"term":"GO:1990528"},{"annotations":[73099,73466,73554,76222],"is_not":false,"summary":null,"term":"GO:0000124"},{"annotations":[70261,73211],"is_not":false,"summary":null,"term":"GO:0001401"},{"annotations":[75077,76414,76469],"is_not":false,"summary":null,"term":"GO:0033309"},{"annotations":[73759,78703],"is_not":false,"summary":null,"term":"GO:0019005"},{"annotations":[72991,73396],"is_not":false,"summary":null,"term":"GO:0005784"},{"annotations":[70222,72944],"is_not":false,"summary":null,"term":"GO:0031207"},{"annotations":[71436,75078],"is_not":false,"summary":null,"term":"GO:0048188"},{"annotations":[77496,77859],"is_not":false,"summary":null,"term":"GO:0034967"},{"annotations":[71579],"is_not":false,"summary":null,"term":"GO:0070824"},{"annotations":[73540],"is_not":false,"summary":null,"term":"GO:0005787"},{"annotations":[72388,74822],"is_not":false,"summary":null,"term":"GO:0005786"},{"annotations":[71306,71732,74659,74684,76919,77735,78097],"is_not":false,"summary":null,"term":"GO:0035861"},{"annotations":[75776],"is_not":false,"summary":null,"term":"GO:0030427"},{"annotations":[74711,77897],"is_not":false,"summary":null,"term":"GO:0055087"},{"annotations":[76532],"is_not":false,"summary":null,"term":"GO:0033557"},{"annotations":[70735,71099,71111,71383,71544,71766,72442,72528,72630,73019,73082,73978,74686,74862,74883,75256,75300,75646,75846,76129,76643,77136,77253,77385,77589,77894,78162,78360,78373,78769],"is_not":false,"summary":null,"term":"GO:0032040"},{"annotations":[70312,72370,74682],"is_not":false,"summary":null,"term":"GO:0030915"},{"annotations":[76078,77948],"is_not":false,"summary":null,"term":"GO:0034719"},{"annotations":[72030,72056,73533,75416,75585,75730,76597,77021],"is_not":false,"summary":null,"term":"GO:0031201"},{"annotations":[75808,78471],"is_not":false,"summary":null,"term":"GO:0005732"},{"annotations":[74948],"is_not":false,"summary":null,"term":"GO:0005876"},{"annotations":[70555,73595,74081,74761,76008,77353],"is_not":false,"summary":null,"term":"GO:0005681"},{"annotations":[75069],"is_not":false,"summary":null,"term":"GO:0032936"},{"annotations":[71774],"is_not":false,"summary":null,"term":"GO:0042709"},{"annotations":[74916],"is_not":false,"summary":null,"term":"GO:0009361"},{"annotations":[74845],"is_not":false,"summary":null,"term":"GO:0031510"},{"annotations":[70219,71647,72558,75319,76834,78745],"is_not":false,"summary":null,"term":"GO:0016514"},{"annotations":[73380,76082,78702],"is_not":false,"summary":null,"term":"GO:0000812"},{"annotations":[72631,75301],"is_not":false,"summary":null,"term":"GO:0034455"},{"annotations":[70924],"is_not":false,"summary":null,"term":"GO:0000333"},{"annotations":[75249,75816],"is_not":false,"summary":null,"term":"GO:0000445"},{"annotations":[73015],"is_not":false,"summary":null,"term":"GO:0042721"},{"annotations":[74532,75008,76115,77569],"is_not":false,"summary":null,"term":"GO:0005744"},{"annotations":[77211,77667],"is_not":false,"summary":null,"term":"GO:0031931"},{"annotations":[76020,76580,77668],"is_not":false,"summary":null,"term":"GO:0031932"},{"annotations":[70351,75449,77132],"is_not":false,"summary":null,"term":"GO:0031499"},{"annotations":[72124,73338,74347,74912,75651,76617,76629,76755,76829,78214,78240,78251,78601],"is_not":false,"summary":null,"term":"GO:0005802"},{"annotations":[72590,75934],"is_not":false,"summary":null,"term":"GO:0070390"},{"annotations":[71931,77468],"is_not":false,"summary":null,"term":"GO:0005672"},{"annotations":[70217,70755,71371,73983,74802,75963,77615,78755],"is_not":false,"summary":null,"term":"GO:0005669"},{"annotations":[70242,75473],"is_not":false,"summary":null,"term":"GO:0005673"},{"annotations":[70218,78899],"is_not":false,"summary":null,"term":"GO:0005674"},{"annotations":[70331,75475,77437],"is_not":false,"summary":null,"term":"GO:0000439"},{"annotations":[70332,73693,75476,77438],"is_not":false,"summary":null,"term":"GO:0005675"},{"annotations":[71871,76639],"is_not":false,"summary":null,"term":"GO:0000126"},{"annotations":[70134,71226,71865,73474,75679],"is_not":false,"summary":null,"term":"GO:0000127"},{"annotations":[75352],"is_not":false,"summary":null,"term":"GO:0070985"},{"annotations":[76281,76638],"is_not":false,"summary":null,"term":"GO:0097550"},{"annotations":[75866],"is_not":false,"summary":null,"term":"GO:0005667"},{"annotations":[72223,73462],"is_not":false,"summary":null,"term":"GO:0018444"},{"annotations":[74231],"is_not":false,"summary":null,"term":"GO:0030133"},{"annotations":[74424],"is_not":false,"summary":null,"term":"GO:1990070"},{"annotations":[71509,74425],"is_not":false,"summary":null,"term":"GO:1990071"},{"annotations":[73341,74426,76666],"is_not":false,"summary":null,"term":"GO:1990072"},{"annotations":[73570,74488],"is_not":false,"summary":null,"term":"GO:0031515"},{"annotations":[71583,73583,77718],"is_not":false,"summary":null,"term":"GO:0000214"},{"annotations":[70275],"is_not":false,"summary":null,"term":"GO:0033596"},{"annotations":[74232],"is_not":false,"summary":null,"term":"GO:0097422"},{"annotations":[70198,70770,72551,72968,73624,74991,75904,76074,77944,78131],"is_not":false,"summary":null,"term":"GO:0005685"},{"annotations":[70586,70771,72208,72552,72999,73544,74699,74992,75102,75251,76075,76381,76574,77945,78761],"is_not":false,"summary":null,"term":"GO:0005686"},{"annotations":[70921,73053,76378,76853],"is_not":false,"summary":null,"term":"GO:0071006"},{"annotations":[71941,76379,76854,76910,78065],"is_not":false,"summary":null,"term":"GO:0071007"},{"annotations":[77591],"is_not":false,"summary":null,"term":"GO:0071008"},{"annotations":[76476],"is_not":false,"summary":null,"term":"GO:0071021"},{"annotations":[70199,70774,72111,72209,72969,73545,75103,75958,77620,78132],"is_not":false,"summary":null,"term":"GO:0071004"},{"annotations":[71265,74767,75203,76573,77331,78529],"is_not":false,"summary":null,"term":"GO:0005684"},{"annotations":[72112,75781],"is_not":false,"summary":null,"term":"GO:0089701"},{"annotations":[70772,72553,74421,76076,77946],"is_not":false,"summary":null,"term":"GO:0005687"},{"annotations":[70773,71047,71720,72555,73809,74994,76321,76369,76475,76603,77108,77355,77553,78064,78472],"is_not":false,"summary":null,"term":"GO:0046540"},{"annotations":[70769,72338,72550,74990,75453,76073,76474,77354,77943],"is_not":false,"summary":null,"term":"GO:0005682"},{"annotations":[71046,71760,76602,77552,77619,78470],"is_not":false,"summary":null,"term":"GO:0005688"},{"annotations":[73643,73679,73824,74646,76650],"is_not":false,"summary":null,"term":"GO:0000151"},{"annotations":[77694],"is_not":false,"summary":null,"term":"GO:1990861"},{"annotations":[74457],"is_not":false,"summary":null,"term":"GO:0043541"},{"annotations":[74262,75632,77040,77387],"is_not":false,"summary":null,"term":"GO:0034456"},{"annotations":[71449,76155],"is_not":false,"summary":null,"term":"GO:1902500"},{"annotations":[73321,74842],"is_not":false,"summary":null,"term":"GO:0005774"},{"annotations":[71320],"is_not":false,"summary":null,"term":"GO:0000221"},{"annotations":[72814,77411],"is_not":false,"summary":null,"term":"GO:0033254"},{"annotations":[70863,74872],"is_not":false,"summary":null,"term":"GO:0034098"},{"annotations":[70292,71073,73932,75800,78205,78390],"is_not":false,"summary":null,"term":"GO:0031982"},{"annotations":[78342],"is_not":false,"summary":null,"term":"GO:0012506"},{"annotations":[73883],"is_not":false,"summary":null,"term":"GO:0005891"},{"annotations":[74743],"is_not":false,"summary":null,"term":"GO:0034424"},{"annotations":[72195,72575],"is_not":false,"summary":null,"term":"GO:0071942"}],"molecular_function":[{"annotations":[74100],"is_not":false,"summary":null,"term":"GO:0019171"},{"annotations":[76097],"is_not":false,"summary":null,"term":"GO:0070626"},{"annotations":[74127,75152,78507],"is_not":false,"summary":null,"term":"GO:0003843"},{"annotations":[71012,72736,74064,75185],"is_not":false,"summary":null,"term":"GO:0042124"},{"annotations":[71316],"is_not":false,"summary":null,"term":"GO:0003949"},{"annotations":[71611,75939],"is_not":false,"summary":null,"term":"GO:0003841"},{"annotations":[75944],"is_not":false,"summary":null,"term":"GO:0047184"},{"annotations":[74045],"is_not":false,"summary":null,"term":"GO:0003847"},{"annotations":[75648],"is_not":false,"summary":null,"term":"GO:0004430"},{"annotations":[73402],"is_not":false,"summary":null,"term":"GO:0005545"},{"annotations":[71389],"is_not":false,"summary":null,"term":"GO:0016303"},{"annotations":[72429],"is_not":false,"summary":null,"term":"GO:0000285"},{"annotations":[78216],"is_not":false,"summary":null,"term":"GO:0016308"},{"annotations":[77054],"is_not":false,"summary":null,"term":"GO:0003842"},{"annotations":[71543,73918,76952,78049,78609],"is_not":false,"summary":null,"term":"GO:0051537"},{"annotations":[72428,75754],"is_not":false,"summary":null,"term":"GO:0047536"},{"annotations":[75921],"is_not":false,"summary":null,"term":"GO:0003852"},{"annotations":[74186,76731],"is_not":false,"summary":null,"term":"GO:0016706"},{"annotations":[77595],"is_not":false,"summary":null,"term":"GO:0052907"},{"annotations":[77635],"is_not":false,"summary":null,"term":"GO:0008441"},{"annotations":[77757],"is_not":false,"summary":null,"term":"GO:0004115"},{"annotations":[77759],"is_not":false,"summary":null,"term":"GO:0047555"},{"annotations":[70984,74158,74292,76668,76987,77286,78175],"is_not":false,"summary":null,"term":"GO:0043138"},{"annotations":[72184,74236],"is_not":false,"summary":null,"term":"GO:0008408"},{"annotations":[73815],"is_not":false,"summary":null,"term":"GO:0034458"},{"annotations":[74589,74939],"is_not":false,"summary":null,"term":"GO:0008296"},{"annotations":[70868],"is_not":false,"summary":null,"term":"GO:0000175"},{"annotations":[73898],"is_not":false,"summary":null,"term":"GO:0048257"},{"annotations":[76943],"is_not":false,"summary":null,"term":"GO:0008686"},{"annotations":[72745],"is_not":false,"summary":null,"term":"GO:0047560"},{"annotations":[73724],"is_not":false,"summary":null,"term":"GO:0008682"},{"annotations":[75883,77037],"is_not":false,"summary":null,"term":"GO:0003849"},{"annotations":[72773],"is_not":false,"summary":null,"term":"GO:0003860"},{"annotations":[74306],"is_not":false,"summary":null,"term":"GO:0003862"},{"annotations":[71118],"is_not":false,"summary":null,"term":"GO:0000253"},{"annotations":[76522],"is_not":false,"summary":null,"term":"GO:0003864"},{"annotations":[76098],"is_not":false,"summary":null,"term":"GO:0004315"},{"annotations":[72071],"is_not":false,"summary":null,"term":"GO:0003866"},{"annotations":[70414,72929,73446,78610],"is_not":false,"summary":null,"term":"GO:0051539"},{"annotations":[72856],"is_not":false,"summary":null,"term":"GO:0046820"},{"annotations":[76300],"is_not":false,"summary":null,"term":"GO:0008412"},{"annotations":[76038],"is_not":false,"summary":null,"term":"GO:0043139"},{"annotations":[77241],"is_not":false,"summary":null,"term":"GO:0008409"},{"annotations":[73411,76803],"is_not":false,"summary":null,"term":"GO:0004534"},{"annotations":[78261],"is_not":false,"summary":null,"term":"GO:0002953"},{"annotations":[74784,76530,77242],"is_not":false,"summary":null,"term":"GO:0017108"},{"annotations":[72463],"is_not":false,"summary":null,"term":"GO:0030272"},{"annotations":[76102],"is_not":false,"summary":null,"term":"GO:0017168"},{"annotations":[71201,72026,72248],"is_not":false,"summary":null,"term":"GO:0008097"},{"annotations":[77510],"is_not":false,"summary":null,"term":"GO:0000906"},{"annotations":[73175,74381,77518,78831],"is_not":false,"summary":null,"term":"GO:0003873"},{"annotations":[76810],"is_not":false,"summary":null,"term":"GO:0003872"},{"annotations":[72695,78645],"is_not":false,"summary":null,"term":"GO:0017057"},{"annotations":[74820],"is_not":false,"summary":null,"term":"GO:0008312"},{"annotations":[73191,73921],"is_not":false,"summary":null,"term":"GO:0034039"},{"annotations":[70407],"is_not":false,"summary":null,"term":"GO:0004314"},{"annotations":[74108,77811],"is_not":false,"summary":null,"term":"GO:0030586"},{"annotations":[75297],"is_not":false,"summary":null,"term":"GO:0004741"},{"annotations":[75006],"is_not":false,"summary":null,"term":"GO:0015421"},{"annotations":[77482],"is_not":false,"summary":null,"term":"GO:0015123"},{"annotations":[78060],"is_not":false,"summary":null,"term":"GO:0003987"},{"annotations":[75554],"is_not":false,"summary":null,"term":"GO:0003984"},{"annotations":[72930],"is_not":false,"summary":null,"term":"GO:0003985"},{"annotations":[76361],"is_not":false,"summary":null,"term":"GO:0003989"},{"annotations":[72218,75841],"is_not":false,"summary":null,"term":"GO:0004042"},{"annotations":[72704],"is_not":false,"summary":null,"term":"GO:0018773"},{"annotations":[74152],"is_not":false,"summary":null,"term":"GO:0003993"},{"annotations":[71381],"is_not":false,"summary":null,"term":"GO:0010309"},{"annotations":[77971],"is_not":false,"summary":null,"term":"GO:0043874"},{"annotations":[72925,73443],"is_not":false,"summary":null,"term":"GO:0003994"},{"annotations":[70273,70293,70559,71074,71590,73933,74313,75044,75546,75678,75801,76449,76781,77159,77685,77801,77989,78208,78372,78500,78681],"is_not":false,"summary":null,"term":"GO:0051015"},{"annotations":[76246],"is_not":false,"summary":null,"term":"GO:0003786"},{"annotations":[72062,75038],"is_not":false,"summary":null,"term":"GO:0003785"},{"annotations":[74984],"is_not":false,"summary":null,"term":"GO:0000035"},{"annotations":[74985],"is_not":false,"summary":null,"term":"GO:0000036"},{"annotations":[70990,77181,77682],"is_not":false,"summary":null,"term":"GO:0047372"},{"annotations":[71486],"is_not":false,"summary":null,"term":"GO:0000140"},{"annotations":[73573],"is_not":false,"summary":null,"term":"GO:0002055"},{"annotations":[73574],"is_not":false,"summary":null,"term":"GO:0003999"},{"annotations":[73187],"is_not":false,"summary":null,"term":"GO:0035485"},{"annotations":[70336],"is_not":false,"summary":null,"term":"GO:0004001"},{"annotations":[76518],"is_not":false,"summary":null,"term":"GO:0004013"},{"annotations":[76575],"is_not":false,"summary":null,"term":"GO:0004014"},{"annotations":[75376],"is_not":false,"summary":null,"term":"GO:0004015"},{"annotations":[70244,70758,71183,75733,77383],"is_not":false,"summary":null,"term":"GO:0000774"},{"annotations":[71917,71997],"is_not":false,"summary":null,"term":"GO:0004017"},{"annotations":[77611],"is_not":false,"summary":null,"term":"GO:0004019"},{"annotations":[74355],"is_not":false,"summary":null,"term":"GO:0004020"},{"annotations":[73609],"is_not":false,"summary":null,"term":"GO:0047631"},{"annotations":[71279,72078],"is_not":false,"summary":null,"term":"GO:0004022"},{"annotations":[76549],"is_not":false,"summary":null,"term":"GO:0008106"},{"annotations":[77074],"is_not":false,"summary":null,"term":"GO:0004024"},{"annotations":[77420,78270],"is_not":false,"summary":null,"term":"GO:0004029"},{"annotations":[73652],"is_not":false,"summary":null,"term":"GO:0004032"},{"annotations":[72829,75436,77425],"is_not":false,"summary":null,"term":"GO:0004033"},{"annotations":[72076],"is_not":false,"summary":null,"term":"GO:0004035"},{"annotations":[74688],"is_not":false,"summary":null,"term":"GO:0004037"},{"annotations":[71480],"is_not":false,"summary":null,"term":"GO:0004555"},{"annotations":[73587,74010,75260,77772,78042,78492],"is_not":false,"summary":null,"term":"GO:0003825"},{"annotations":[74118,74314,74374,74913,76105,76405,76961,78054],"is_not":false,"summary":null,"term":"GO:0000026"},{"annotations":[70812,71597,72936,73119,77598],"is_not":false,"summary":null,"term":"GO:0047657"},{"annotations":[72861],"is_not":false,"summary":null,"term":"GO:0000033"},{"annotations":[70236,71907,78891],"is_not":false,"summary":null,"term":"GO:0000009"},{"annotations":[76118],"is_not":false,"summary":null,"term":"GO:0090599"},{"annotations":[72332],"is_not":false,"summary":null,"term":"GO:0004044"},{"annotations":[73034,74769,74894,75442,75911,75932,76658,76674,77493,78518,78729,78882],"is_not":false,"summary":null,"term":"GO:0015171"},{"annotations":[75226,76796],"is_not":false,"summary":null,"term":"GO:0004045"},{"annotations":[74780],"is_not":false,"summary":null,"term":"GO:0008519"},{"annotations":[70382,73575,76811],"is_not":false,"summary":null,"term":"GO:0016208"},{"annotations":[75634],"is_not":false,"summary":null,"term":"GO:0003876"},{"annotations":[75724,77836,77879,78555,78819],"is_not":false,"summary":null,"term":"GO:0010997"},{"annotations":[71801,75757],"is_not":false,"summary":null,"term":"GO:0015297"},{"annotations":[73828],"is_not":false,"summary":null,"term":"GO:0004059"},{"annotations":[70668],"is_not":false,"summary":null,"term":"GO:0004053"},{"annotations":[75573],"is_not":false,"summary":null,"term":"GO:0004814"},{"annotations":[70576],"is_not":false,"summary":null,"term":"GO:0004056"},{"annotations":[70844],"is_not":false,"summary":null,"term":"GO:0004055"},{"annotations":[72234],"is_not":false,"summary":null,"term":"GO:0004057"},{"annotations":[74031,74666],"is_not":false,"summary":null,"term":"GO:0071933"},{"annotations":[73943],"is_not":false,"summary":null,"term":"GO:0004067"},{"annotations":[77967],"is_not":false,"summary":null,"term":"GO:0004066"},{"annotations":[71329,71827],"is_not":false,"summary":null,"term":"GO:0004070"},{"annotations":[73306],"is_not":false,"summary":null,"term":"GO:0004072"},{"annotations":[75305],"is_not":false,"summary":null,"term":"GO:0004073"},{"annotations":[75898,75983],"is_not":false,"summary":null,"term":"GO:0004815"},{"annotations":[70241,71809,72921,75230,78501],"is_not":false,"summary":null,"term":"GO:0004190"},{"annotations":[73214],"is_not":false,"summary":null,"term":"GO:0019778"},{"annotations":[73215],"is_not":false,"summary":null,"term":"GO:0019779"},{"annotations":[72802],"is_not":false,"summary":null,"term":"GO:0019776"},{"annotations":[71624,71996,72319,72397,72728,72852,73514,73628,75623,76700,76750,76813,78816],"is_not":false,"summary":null,"term":"GO:0005524"},{"annotations":[70268,70458,70891,70900,71031,71087,71677,71754,72214,72361,72476,72727,73038,73125,73500,73858,74072,74285,74601,74871,75237,75281,75496,76957,77672,77784,78142,78757,78904],"is_not":false,"summary":null,"term":"GO:0016887"},{"annotations":[77316],"is_not":false,"summary":null,"term":"GO:0003879"},{"annotations":[78147,78909],"is_not":false,"summary":null,"term":"GO:0140658"},{"annotations":[76706],"is_not":false,"summary":null,"term":"GO:0047453"},{"annotations":[72295,77113],"is_not":false,"summary":null,"term":"GO:0004176"},{"annotations":[70799],"is_not":false,"summary":null,"term":"GO:0046404"},{"annotations":[70441,74429],"is_not":false,"summary":null,"term":"GO:0052929"},{"annotations":[73676,77832],"is_not":false,"summary":null,"term":"GO:0001671"},{"annotations":[73771],"is_not":false,"summary":null,"term":"GO:0051117"},{"annotations":[70997,74568,78658],"is_not":false,"summary":null,"term":"GO:0019829"},{"annotations":[73941],"is_not":false,"summary":null,"term":"GO:0008798"},{"annotations":[75991],"is_not":false,"summary":null,"term":"GO:0048487"},{"annotations":[78047],"is_not":false,"summary":null,"term":"GO:0004076"},{"annotations":[77640],"is_not":false,"summary":null,"term":"GO:0004077"},{"annotations":[77872],"is_not":false,"summary":null,"term":"GO:0034431"},{"annotations":[77873],"is_not":false,"summary":null,"term":"GO:0034432"},{"annotations":[70327],"is_not":false,"summary":null,"term":"GO:0080139"},{"annotations":[74058],"is_not":false,"summary":null,"term":"GO:0034513"},{"annotations":[70297],"is_not":false,"summary":null,"term":"GO:0000254"},{"annotations":[74762,77829],"is_not":false,"summary":null,"term":"GO:0000248"},{"annotations":[71425,73586],"is_not":false,"summary":null,"term":"GO:0004662"},{"annotations":[75025],"is_not":false,"summary":null,"term":"GO:0015086"},{"annotations":[72358],"is_not":false,"summary":null,"term":"GO:0005262"},{"annotations":[73743,74521,77278,77802,78005],"is_not":false,"summary":null,"term":"GO:0005509"},{"annotations":[72794,78441],"is_not":false,"summary":null,"term":"GO:0005227"},{"annotations":[72820],"is_not":false,"summary":null,"term":"GO:0008597"},{"annotations":[70452,77266],"is_not":false,"summary":null,"term":"GO:0015369"},{"annotations":[73072,74509,76446,78263],"is_not":false,"summary":null,"term":"GO:0005516"},{"annotations":[73073,73115,74510],"is_not":false,"summary":null,"term":"GO:0004683"},{"annotations":[78267],"is_not":false,"summary":null,"term":"GO:0033192"},{"annotations":[71040],"is_not":false,"summary":null,"term":"GO:0030552"},{"annotations":[73161],"is_not":false,"summary":null,"term":"GO:0004691"},{"annotations":[71043],"is_not":false,"summary":null,"term":"GO:0004862"},{"annotations":[70539,71330,71828],"is_not":false,"summary":null,"term":"GO:0004088"},{"annotations":[71101,72750,72941,72972,74362,75551],"is_not":false,"summary":null,"term":"GO:0005351"},{"annotations":[76581],"is_not":false,"summary":null,"term":"GO:0004089"},{"annotations":[71198,78436,78604],"is_not":false,"summary":null,"term":"GO:0046943"},{"annotations":[70472,70948],"is_not":false,"summary":null,"term":"GO:0052689"},{"annotations":[72791],"is_not":false,"summary":null,"term":"GO:0004180"},{"annotations":[71123],"is_not":false,"summary":null,"term":"GO:0004096"},{"annotations":[71403],"is_not":false,"summary":null,"term":"GO:0008444"},{"annotations":[75747],"is_not":false,"summary":null,"term":"GO:0003881"},{"annotations":[73776,73973],"is_not":false,"summary":null,"term":"GO:0004100"},{"annotations":[77270],"is_not":false,"summary":null,"term":"GO:0004568"},{"annotations":[70535],"is_not":false,"summary":null,"term":"GO:0005254"},{"annotations":[73110],"is_not":false,"summary":null,"term":"GO:0004103"},{"annotations":[70179],"is_not":false,"summary":null,"term":"GO:0004105"},{"annotations":[74466],"is_not":false,"summary":null,"term":"GO:0004106"},{"annotations":[72456],"is_not":false,"summary":null,"term":"GO:0004107"},{"annotations":[70187,70649,71244,71739,72262,72641,73334,73836,75318,75608,76393,76631,77457,77623,78141,78455,78744,78753],"is_not":false,"summary":null,"term":"GO:0003682"},{"annotations":[70563,76026,78392],"is_not":false,"summary":null,"term":"GO:0031490"},{"annotations":[73934],"is_not":false,"summary":null,"term":"GO:0004108"},{"annotations":[72438],"is_not":false,"summary":null,"term":"GO:0071913"},{"annotations":[71897,73821,76552,77186],"is_not":false,"summary":null,"term":"GO:0035615"},{"annotations":[73455,78362,78386],"is_not":false,"summary":null,"term":"GO:0030276"},{"annotations":[73408],"is_not":false,"summary":null,"term":"GO:0032050"},{"annotations":[75840],"is_not":false,"summary":null,"term":"GO:0032051"},{"annotations":[70702],"is_not":false,"summary":null,"term":"GO:0015228"},{"annotations":[71973],"is_not":false,"summary":null,"term":"GO:0061775"},{"annotations":[76176],"is_not":false,"summary":null,"term":"GO:0097020"},{"annotations":[74505,76764,77095],"is_not":false,"summary":null,"term":"GO:0005507"},{"annotations":[78511],"is_not":false,"summary":null,"term":"GO:0004109"},{"annotations":[71349],"is_not":false,"summary":null,"term":"GO:0001046"},{"annotations":[76506],"is_not":false,"summary":null,"term":"GO:0051267"},{"annotations":[74804],"is_not":false,"summary":null,"term":"GO:0000402"},{"annotations":[73892,76531,77372,77914],"is_not":false,"summary":null,"term":"GO:0008821"},{"annotations":[74481],"is_not":false,"summary":null,"term":"GO:0003883"},{"annotations":[72918,73682,73734,76436],"is_not":false,"summary":null,"term":"GO:0097602"},{"annotations":[71644,73642],"is_not":false,"summary":null,"term":"GO:0030332"},{"annotations":[70618,73763,78426],"is_not":false,"summary":null,"term":"GO:0061575"},{"annotations":[75354,77976,78123,78533],"is_not":false,"summary":null,"term":"GO:0004693"},{"annotations":[70370,70788,71526,73347,77854],"is_not":false,"summary":null,"term":"GO:0016538"},{"annotations":[74735,76865,76870,76940,78617],"is_not":false,"summary":null,"term":"GO:0016018"},{"annotations":[74719],"is_not":false,"summary":null,"term":"GO:0003962"},{"annotations":[77533],"is_not":false,"summary":null,"term":"GO:0031071"},{"annotations":[72489,76543],"is_not":false,"summary":null,"term":"GO:0004124"},{"annotations":[74866],"is_not":false,"summary":null,"term":"GO:0033229"},{"annotations":[72321],"is_not":false,"summary":null,"term":"GO:0004817"},{"annotations":[73889,75569,75615,75946,76426,77100],"is_not":false,"summary":null,"term":"GO:0004843"},{"annotations":[73663],"is_not":false,"summary":null,"term":"GO:0004197"},{"annotations":[70145],"is_not":false,"summary":null,"term":"GO:0004126"},{"annotations":[78864],"is_not":false,"summary":null,"term":"GO:0004127"},{"annotations":[76692,76975],"is_not":false,"summary":null,"term":"GO:0004128"},{"annotations":[71749,78576],"is_not":false,"summary":null,"term":"GO:0140659"},{"annotations":[78856],"is_not":false,"summary":null,"term":"GO:0003884"},{"annotations":[75241],"is_not":false,"summary":null,"term":"GO:0003885"},{"annotations":[73425],"is_not":false,"summary":null,"term":"GO:0017050"},{"annotations":[78802],"is_not":false,"summary":null,"term":"GO:0004458"},{"annotations":[78800],"is_not":false,"summary":null,"term":"GO:0008720"},{"annotations":[73482],"is_not":false,"summary":null,"term":"GO:0004750"},{"annotations":[77664],"is_not":false,"summary":null,"term":"GO:0008721"},{"annotations":[73473],"is_not":false,"summary":null,"term":"GO:0051500"},{"annotations":[70212,72192,72572,74391,74680],"is_not":false,"summary":null,"term":"GO:0003684"},{"annotations":[78111],"is_not":false,"summary":null,"term":"GO:0019239"},{"annotations":[71951,74009],"is_not":false,"summary":null,"term":"GO:0045547"},{"annotations":[78784],"is_not":false,"summary":null,"term":"GO:0050613"},{"annotations":[78848],"is_not":false,"summary":null,"term":"GO:0000246"},{"annotations":[71232,75372,77731],"is_not":false,"summary":null,"term":"GO:0019784"},{"annotations":[70731],"is_not":false,"summary":null,"term":"GO:0017125"},{"annotations":[71576],"is_not":false,"summary":null,"term":"GO:0019135"},{"annotations":[71024],"is_not":false,"summary":null,"term":"GO:0034038"},{"annotations":[75149],"is_not":false,"summary":null,"term":"GO:0070694"},{"annotations":[71303,71570],"is_not":false,"summary":null,"term":"GO:0004140"},{"annotations":[70182],"is_not":false,"summary":null,"term":"GO:0016929"},{"annotations":[75377],"is_not":false,"summary":null,"term":"GO:0004141"},{"annotations":[71504],"is_not":false,"summary":null,"term":"GO:0101005"},{"annotations":[76067],"is_not":false,"summary":null,"term":"GO:0004144"},{"annotations":[71140],"is_not":false,"summary":null,"term":"GO:0004146"},{"annotations":[78076],"is_not":false,"summary":null,"term":"GO:0008841"},{"annotations":[73157,74161],"is_not":false,"summary":null,"term":"GO:0004742"},{"annotations":[75109],"is_not":false,"summary":null,"term":"GO:0004149"},{"annotations":[71331,71689,71829],"is_not":false,"summary":null,"term":"GO:0004151"},{"annotations":[78399],"is_not":false,"summary":null,"term":"GO:0004156"},{"annotations":[71416],"is_not":false,"summary":null,"term":"GO:0004160"},{"annotations":[70859,77450],"is_not":false,"summary":null,"term":"GO:0004161"},{"annotations":[71826],"is_not":false,"summary":null,"term":"GO:0071916"},{"annotations":[70390],"is_not":false,"summary":null,"term":"GO:0008239"},{"annotations":[71240],"is_not":false,"summary":null,"term":"GO:0033857"},{"annotations":[77865],"is_not":false,"summary":null,"term":"GO:0008486"},{"annotations":[76134],"is_not":false,"summary":null,"term":"GO:0004163"},{"annotations":[78727],"is_not":false,"summary":null,"term":"GO:0061685"},{"annotations":[75985],"is_not":false,"summary":null,"term":"GO:0017178"},{"annotations":[70551,70753,72640,72716,72952,73036,73178,73779,76170,77495,77562,78140,78273,78454,78814,78902],"is_not":false,"summary":null,"term":"GO:0003677"},{"annotations":[71245,72506,75508,76205,76840],"is_not":false,"summary":null,"term":"GO:0003689"},{"annotations":[72042],"is_not":false,"summary":null,"term":"GO:0003678"},{"annotations":[78815],"is_not":false,"summary":null,"term":"GO:0003910"},{"annotations":[71298],"is_not":false,"summary":null,"term":"GO:0030337"},{"annotations":[72225,74580,74975],"is_not":false,"summary":null,"term":"GO:0000150"},{"annotations":[70955,76670],"is_not":false,"summary":null,"term":"GO:0015616"},{"annotations":[72963],"is_not":false,"summary":null,"term":"GO:0003906"},{"annotations":[74965,78319,78723],"is_not":false,"summary":null,"term":"GO:0001228"},{"annotations":[72053,72849,77230],"is_not":false,"summary":null,"term":"GO:0003700"},{"annotations":[72808,72812,76199],"is_not":false,"summary":null,"term":"GO:0000981"},{"annotations":[76455,77741],"is_not":false,"summary":null,"term":"GO:0003899"},{"annotations":[70730,73220,73685,74237,74590,75999,76915],"is_not":false,"summary":null,"term":"GO:0003887"},{"annotations":[75779],"is_not":false,"summary":null,"term":"GO:0052925"},{"annotations":[78635],"is_not":false,"summary":null,"term":"GO:0004168"},{"annotations":[78486],"is_not":false,"summary":null,"term":"GO:0042283"},{"annotations":[76193],"is_not":false,"summary":null,"term":"GO:0042281"},{"annotations":[75670],"is_not":false,"summary":null,"term":"GO:0004579"},{"annotations":[71325],"is_not":false,"summary":null,"term":"GO:0004582"},{"annotations":[70172,74413,76230],"is_not":false,"summary":null,"term":"GO:0004169"},{"annotations":[73167],"is_not":false,"summary":null,"term":"GO:0047874"},{"annotations":[72962],"is_not":false,"summary":null,"term":"GO:0008311"},{"annotations":[70330,70610,70796,72226,74581,74976,76988,77057,77958],"is_not":false,"summary":null,"term":"GO:0003690"},{"annotations":[73804],"is_not":false,"summary":null,"term":"GO:0003691"},{"annotations":[78001],"is_not":false,"summary":null,"term":"GO:0004170"},{"annotations":[76354],"is_not":false,"summary":null,"term":"GO:0045504"},{"annotations":[76353],"is_not":false,"summary":null,"term":"GO:0045503"},{"annotations":[75222],"is_not":false,"summary":null,"term":"GO:0009055"},{"annotations":[73365],"is_not":false,"summary":null,"term":"GO:0004519"},{"annotations":[73756,76972],"is_not":false,"summary":null,"term":"GO:0061133"},{"annotations":[74823],"is_not":false,"summary":null,"term":"GO:0030942"},{"annotations":[70691,77864],"is_not":false,"summary":null,"term":"GO:0000298"},{"annotations":[75626,78741],"is_not":false,"summary":null,"term":"GO:0034737"},{"annotations":[73111],"is_not":false,"summary":null,"term":"GO:0004305"},{"annotations":[74959],"is_not":false,"summary":null,"term":"GO:0004306"},{"annotations":[72085],"is_not":false,"summary":null,"term":"GO:0071074"},{"annotations":[74678],"is_not":false,"summary":null,"term":"GO:0004694"},{"annotations":[70693,71978],"is_not":false,"summary":null,"term":"GO:0004309"},{"annotations":[70570,71011,71813,75523],"is_not":false,"summary":null,"term":"GO:0071949"},{"annotations":[73523],"is_not":false,"summary":null,"term":"GO:0015230"},{"annotations":[75362],"is_not":false,"summary":null,"term":"GO:0004310"},{"annotations":[72257],"is_not":false,"summary":null,"term":"GO:0080132"},{"annotations":[76725],"is_not":false,"summary":null,"term":"GO:0009922"},{"annotations":[78869],"is_not":false,"summary":null,"term":"GO:0047617"},{"annotations":[73947],"is_not":false,"summary":null,"term":"GO:0004325"},{"annotations":[76948],"is_not":false,"summary":null,"term":"GO:0008198"},{"annotations":[70579],"is_not":false,"summary":null,"term":"GO:0015093"},{"annotations":[71891],"is_not":false,"summary":null,"term":"GO:0033149"},{"annotations":[74809,77244],"is_not":false,"summary":null,"term":"GO:0070336"},{"annotations":[70951,74111,75225,75337,75410,75558,75594,76197,77174,77814,77848],"is_not":false,"summary":null,"term":"GO:0050660"},{"annotations":[70949,75335],"is_not":false,"summary":null,"term":"GO:0016971"},{"annotations":[77783],"is_not":false,"summary":null,"term":"GO:1903425"},{"annotations":[77487],"is_not":false,"summary":null,"term":"GO:0003919"},{"annotations":[72455,74106,75591,76194,77170,77809],"is_not":false,"summary":null,"term":"GO:0010181"},{"annotations":[73522],"is_not":false,"summary":null,"term":"GO:0008517"},{"annotations":[76984,77371,78172],"is_not":false,"summary":null,"term":"GO:0000400"},{"annotations":[70980,76983,77282,78171],"is_not":false,"summary":null,"term":"GO:0009378"},{"annotations":[70517,75396],"is_not":false,"summary":null,"term":"GO:0008865"},{"annotations":[72770,74382,75446,77519],"is_not":false,"summary":null,"term":"GO:0004331"},{"annotations":[76818],"is_not":false,"summary":null,"term":"GO:0070095"},{"annotations":[71313,72840],"is_not":false,"summary":null,"term":"GO:0004332"},{"annotations":[78008],"is_not":false,"summary":null,"term":"GO:0004333"},{"annotations":[72315],"is_not":false,"summary":null,"term":"GO:0001965"},{"annotations":[75997],"is_not":false,"summary":null,"term":"GO:0098505"},{"annotations":[76311],"is_not":false,"summary":null,"term":"GO:0004335"},{"annotations":[75785],"is_not":false,"summary":null,"term":"GO:0003839"},{"annotations":[72252,74573],"is_not":false,"summary":null,"term":"GO:0019003"},{"annotations":[70724,75514],"is_not":false,"summary":null,"term":"GO:0004382"},{"annotations":[72084],"is_not":false,"summary":null,"term":"GO:0005092"},{"annotations":[75965],"is_not":false,"summary":null,"term":"GO:0004377"},{"annotations":[71802],"is_not":false,"summary":null,"term":"GO:0005458"},{"annotations":[70860,77451],"is_not":false,"summary":null,"term":"GO:0004337"},{"annotations":[77720],"is_not":false,"summary":null,"term":"GO:0004573"},{"annotations":[73787,76801,78797],"is_not":false,"summary":null,"term":"GO:0042973"},{"annotations":[72951],"is_not":false,"summary":null,"term":"GO:0046557"},{"annotations":[70519,75399],"is_not":false,"summary":null,"term":"GO:0004340"},{"annotations":[78560],"is_not":false,"summary":null,"term":"GO:0046316"},{"annotations":[70830],"is_not":false,"summary":null,"term":"GO:0004343"},{"annotations":[70403],"is_not":false,"summary":null,"term":"GO:0004347"},{"annotations":[74595,75907],"is_not":false,"summary":null,"term":"GO:0015926"},{"annotations":[70229],"is_not":false,"summary":null,"term":"GO:0004349"},{"annotations":[78039],"is_not":false,"summary":null,"term":"GO:0004351"},{"annotations":[72580],"is_not":false,"summary":null,"term":"GO:0004354"},{"annotations":[72059],"is_not":false,"summary":null,"term":"GO:0016040"},{"annotations":[75248],"is_not":false,"summary":null,"term":"GO:0004350"},{"annotations":[76466],"is_not":false,"summary":null,"term":"GO:0004357"},{"annotations":[70434,72638],"is_not":false,"summary":null,"term":"GO:0004818"},{"annotations":[76471,77319],"is_not":false,"summary":null,"term":"GO:0004359"},{"annotations":[71477],"is_not":false,"summary":null,"term":"GO:0004356"},{"annotations":[77079],"is_not":false,"summary":null,"term":"GO:0004360"},{"annotations":[71861,74541],"is_not":false,"summary":null,"term":"GO:0050567"},{"annotations":[70768],"is_not":false,"summary":null,"term":"GO:0043295"},{"annotations":[73068,77433],"is_not":false,"summary":null,"term":"GO:0015038"},{"annotations":[70916],"is_not":false,"summary":null,"term":"GO:0016756"},{"annotations":[70766],"is_not":false,"summary":null,"term":"GO:0004363"},{"annotations":[77842],"is_not":false,"summary":null,"term":"GO:0004362"},{"annotations":[72335,74245,78870],"is_not":false,"summary":null,"term":"GO:0004365"},{"annotations":[70252,70794],"is_not":false,"summary":null,"term":"GO:0004366"},{"annotations":[77454],"is_not":false,"summary":null,"term":"GO:0004371"},{"annotations":[70251,70793],"is_not":false,"summary":null,"term":"GO:0016287"},{"annotations":[71680],"is_not":false,"summary":null,"term":"GO:0047389"},{"annotations":[73665],"is_not":false,"summary":null,"term":"GO:0016594"},{"annotations":[73668],"is_not":false,"summary":null,"term":"GO:0004375"},{"annotations":[72156,73146],"is_not":false,"summary":null,"term":"GO:0004372"},{"annotations":[72732],"is_not":false,"summary":null,"term":"GO:0004820"},{"annotations":[77062],"is_not":false,"summary":null,"term":"GO:0004379"},{"annotations":[72523,74061],"is_not":false,"summary":null,"term":"GO:0019172"},{"annotations":[74624,74651],"is_not":false,"summary":null,"term":"GO:0030267"},{"annotations":[74133],"is_not":false,"summary":null,"term":"GO:0003921"},{"annotations":[70375,71051,71189,71708,72253,72259,72495,73102,73133,73170,73294,73708,73853,74431,74574,75121,76339,76389,76646,76876,76890,77778,78488,78698],"is_not":false,"summary":null,"term":"GO:0005525"},{"annotations":[70374],"is_not":false,"summary":null,"term":"GO:0003934"},{"annotations":[70277,70316,70363,71560,72049,73323,74324,74910,75872,75890,75988,77091,77336,78465],"is_not":false,"summary":null,"term":"GO:0005096"},{"annotations":[70233,70386,70865,71130,71188,71465,71512,71547,71707,72222,72258,72583,72594,73101,73132,73707,73852,74204,74335,74361,74572,74821,75120,75178,75295,75527,75992,76140,76264,76338,76388,76489,76645,76782,76889,77272,78063,78307,78401,78859],"is_not":false,"summary":null,"term":"GO:0003924"},{"annotations":[73738],"is_not":false,"summary":null,"term":"GO:0051020"},{"annotations":[70661,75270],"is_not":false,"summary":null,"term":"GO:0030695"},{"annotations":[77658],"is_not":false,"summary":null,"term":"GO:0008892"},{"annotations":[74892],"is_not":false,"summary":null,"term":"GO:0001409"},{"annotations":[70185,72122,72317,73560,73581,74233,74817,77141,77194,77408,78885],"is_not":false,"summary":null,"term":"GO:0005085"},{"annotations":[75211],"is_not":false,"summary":null,"term":"GO:0004385"},{"annotations":[70340,70892,70975,71755,72362,72477,75238,78758],"is_not":false,"summary":null,"term":"GO:0031072"},{"annotations":[70368],"is_not":false,"summary":null,"term":"GO:0004386"},{"annotations":[70598,71122,76974,77154],"is_not":false,"summary":null,"term":"GO:0020037"},{"annotations":[73882],"is_not":false,"summary":null,"term":"GO:0008331"},{"annotations":[70781,72244],"is_not":false,"summary":null,"term":"GO:0140107"},{"annotations":[76828],"is_not":false,"summary":null,"term":"GO:0009927"},{"annotations":[77447],"is_not":false,"summary":null,"term":"GO:0004821"},{"annotations":[78879],"is_not":false,"summary":null,"term":"GO:0004399"},{"annotations":[75818],"is_not":false,"summary":null,"term":"GO:0004401"},{"annotations":[74925],"is_not":false,"summary":null,"term":"GO:0008469"},{"annotations":[70190,70269,71648,72217,73043,73762,73839,74068,76493,76835,77626,78148,78440,78910],"is_not":false,"summary":null,"term":"GO:0042393"},{"annotations":[73868],"is_not":false,"summary":null,"term":"GO:0043998"},{"annotations":[73086],"is_not":false,"summary":null,"term":"GO:1990259"},{"annotations":[70626],"is_not":false,"summary":null,"term":"GO:0051864"},{"annotations":[70463,71853,74409],"is_not":false,"summary":null,"term":"GO:0034647"},{"annotations":[72494],"is_not":false,"summary":null,"term":"GO:0032931"},{"annotations":[70625],"is_not":false,"summary":null,"term":"GO:0032454"},{"annotations":[77053],"is_not":false,"summary":null,"term":"GO:0072354"},{"annotations":[73866],"is_not":false,"summary":null,"term":"GO:0010485"},{"annotations":[71902],"is_not":false,"summary":null,"term":"GO:0046972"},{"annotations":[74398],"is_not":false,"summary":null,"term":"GO:0008897"},{"annotations":[72526,76188],"is_not":false,"summary":null,"term":"GO:0004408"},{"annotations":[75533],"is_not":false,"summary":null,"term":"GO:0004410"},{"annotations":[70886],"is_not":false,"summary":null,"term":"GO:0047046"},{"annotations":[71256],"is_not":false,"summary":null,"term":"GO:0004412"},{"annotations":[75358,75465],"is_not":false,"summary":null,"term":"GO:0004414"},{"annotations":[71224,76847,78394,78591],"is_not":false,"summary":null,"term":"GO:0030544"},{"annotations":[75708,75823,76850,78397],"is_not":false,"summary":null,"term":"GO:0051879"},{"annotations":[75617],"is_not":false,"summary":null,"term":"GO:0016788"},{"annotations":[75231],"is_not":false,"summary":null,"term":"GO:0004553"},{"annotations":[73271],"is_not":false,"summary":null,"term":"GO:0004416"},{"annotations":[75485],"is_not":false,"summary":null,"term":"GO:0004418"},{"annotations":[78715],"is_not":false,"summary":null,"term":"GO:0004421"},{"annotations":[70509,73616,73660],"is_not":false,"summary":null,"term":"GO:0008902"},{"annotations":[74623,74650],"is_not":false,"summary":null,"term":"GO:0016618"},{"annotations":[74755],"is_not":false,"summary":null,"term":"GO:0004422"},{"annotations":[74957],"is_not":false,"summary":null,"term":"GO:0004424"},{"annotations":[75202],"is_not":false,"summary":null,"term":"GO:0000107"},{"annotations":[70228],"is_not":false,"summary":null,"term":"GO:0050483"},{"annotations":[70140],"is_not":false,"summary":null,"term":"GO:0003937"},{"annotations":[74298],"is_not":false,"summary":null,"term":"GO:0003938"},{"annotations":[78126],"is_not":false,"summary":null,"term":"GO:0004425"},{"annotations":[70204,77698],"is_not":false,"summary":null,"term":"GO:0004427"},{"annotations":[71083,77537],"is_not":false,"summary":null,"term":"GO:0005315"},{"annotations":[71236],"is_not":false,"summary":null,"term":"GO:0000829"},{"annotations":[71933],"is_not":false,"summary":null,"term":"GO:0000822"},{"annotations":[71443,74792],"is_not":false,"summary":null,"term":"GO:0000828"},{"annotations":[76332],"is_not":false,"summary":null,"term":"GO:0008934"},{"annotations":[74352],"is_not":false,"summary":null,"term":"GO:0035299"},{"annotations":[73333],"is_not":false,"summary":null,"term":"GO:0045140"},{"annotations":[75441],"is_not":false,"summary":null,"term":"GO:0070917"},{"annotations":[74791],"is_not":false,"summary":null,"term":"GO:0000824"},{"annotations":[74793],"is_not":false,"summary":null,"term":"GO:0008440"},{"annotations":[70410,74610,76749,78605],"is_not":false,"summary":null,"term":"GO:0005506"},{"annotations":[70881],"is_not":false,"summary":null,"term":"GO:0004449"},{"annotations":[73429],"is_not":false,"summary":null,"term":"GO:0004450"},{"annotations":[71663,74668],"is_not":false,"summary":null,"term":"GO:0004822"},{"annotations":[74478],"is_not":false,"summary":null,"term":"GO:0004452"},{"annotations":[76317],"is_not":false,"summary":null,"term":"GO:0036435"},{"annotations":[77885],"is_not":false,"summary":null,"term":"GO:0061578"},{"annotations":[76123],"is_not":false,"summary":null,"term":"GO:0004455"},{"annotations":[73268],"is_not":false,"summary":null,"term":"GO:0016212"},{"annotations":[78059],"is_not":false,"summary":null,"term":"GO:0004021"},{"annotations":[72003],"is_not":false,"summary":null,"term":"GO:0008732"},{"annotations":[77893],"is_not":false,"summary":null,"term":"GO:0061459"},{"annotations":[71156,76588],"is_not":false,"summary":null,"term":"GO:0004069"},{"annotations":[77890],"is_not":false,"summary":null,"term":"GO:0005313"},{"annotations":[77888],"is_not":false,"summary":null,"term":"GO:0005290"},{"annotations":[72843],"is_not":false,"summary":null,"term":"GO:0003939"},{"annotations":[77886],"is_not":false,"summary":null,"term":"GO:0015189"},{"annotations":[73797],"is_not":false,"summary":null,"term":"GO:0030060"},{"annotations":[76719],"is_not":false,"summary":null,"term":"GO:0000064"},{"annotations":[76681],"is_not":false,"summary":null,"term":"GO:0003941"},{"annotations":[77887],"is_not":false,"summary":null,"term":"GO:0015194"},{"annotations":[77889],"is_not":false,"summary":null,"term":"GO:0005302"},{"annotations":[73717],"is_not":false,"summary":null,"term":"GO:0000250"},{"annotations":[70584,71617,74225],"is_not":false,"summary":null,"term":"GO:0070180"},{"annotations":[75100,76927],"is_not":false,"summary":null,"term":"GO:0004823"},{"annotations":[73723],"is_not":false,"summary":null,"term":"GO:0016298"},{"annotations":[70120,71606,72733,73492,74326,76327],"is_not":false,"summary":null,"term":"GO:0008289"},{"annotations":[74552],"is_not":false,"summary":null,"term":"GO:0016992"},{"annotations":[70890],"is_not":false,"summary":null,"term":"GO:0033819"},{"annotations":[77001],"is_not":false,"summary":null,"term":"GO:0017118"},{"annotations":[75243],"is_not":false,"summary":null,"term":"GO:0036042"},{"annotations":[70907,74717,76017,77750],"is_not":false,"summary":null,"term":"GO:0070577"},{"annotations":[71807,73353],"is_not":false,"summary":null,"term":"GO:0004824"},{"annotations":[70969],"is_not":false,"summary":null,"term":"GO:0042171"},{"annotations":[70826],"is_not":false,"summary":null,"term":"GO:0004622"},{"annotations":[71229,72996,76521,77999,78419],"is_not":false,"summary":null,"term":"GO:0000287"},{"annotations":[70477,74040,75023,76462],"is_not":false,"summary":null,"term":"GO:0015095"},{"annotations":[73026],"is_not":false,"summary":null,"term":"GO:0004471"},{"annotations":[70667,76185],"is_not":false,"summary":null,"term":"GO:0030145"},{"annotations":[73315,75026],"is_not":false,"summary":null,"term":"GO:0005384"},{"annotations":[75397],"is_not":false,"summary":null,"term":"GO:0019158"},{"annotations":[74857],"is_not":false,"summary":null,"term":"GO:0004475"},{"annotations":[76879],"is_not":false,"summary":null,"term":"GO:0004476"},{"annotations":[71845,77207],"is_not":false,"summary":null,"term":"GO:0051377"},{"annotations":[74746],"is_not":false,"summary":null,"term":"GO:0000030"},{"annotations":[74080],"is_not":false,"summary":null,"term":"GO:0004707"},{"annotations":[71553],"is_not":false,"summary":null,"term":"GO:0004708"},{"annotations":[71222],"is_not":false,"summary":null,"term":"GO:0033550"},{"annotations":[71218],"is_not":false,"summary":null,"term":"GO:0017017"},{"annotations":[70398],"is_not":false,"summary":null,"term":"GO:0005078"},{"annotations":[76040],"is_not":false,"summary":null,"term":"GO:0031956"},{"annotations":[73901,77370,77513],"is_not":false,"summary":null,"term":"GO:0032977"},{"annotations":[73483,77921],"is_not":false,"summary":null,"term":"GO:0046872"},{"annotations":[72764,73875],"is_not":false,"summary":null,"term":"GO:0070006"},{"annotations":[70157,70249,74319,75108,75844,76384,76498,77043,77117],"is_not":false,"summary":null,"term":"GO:0004222"},{"annotations":[75371],"is_not":false,"summary":null,"term":"GO:0008237"},{"annotations":[75057,75717],"is_not":false,"summary":null,"term":"GO:0004477"},{"annotations":[74615],"is_not":false,"summary":null,"term":"GO:0004478"},{"annotations":[77259],"is_not":false,"summary":null,"term":"GO:0004825"},{"annotations":[77035],"is_not":false,"summary":null,"term":"GO:0004479"},{"annotations":[75291,76223,76345,77498,77654],"is_not":false,"summary":null,"term":"GO:0035064"},{"annotations":[70634],"is_not":false,"summary":null,"term":"GO:0004487"},{"annotations":[75058,75718],"is_not":false,"summary":null,"term":"GO:0004488"},{"annotations":[77219,78622],"is_not":false,"summary":null,"term":"GO:0046570"},{"annotations":[73654],"is_not":false,"summary":null,"term":"GO:0008168"},{"annotations":[78583],"is_not":false,"summary":null,"term":"GO:0004496"},{"annotations":[70288,71069,73928,75796,78199],"is_not":false,"summary":null,"term":"GO:0000146"},{"annotations":[73502,73744,75283,75688,76119,76181,77674],"is_not":false,"summary":null,"term":"GO:0008017"},{"annotations":[78615],"is_not":false,"summary":null,"term":"GO:0051010"},{"annotations":[76244],"is_not":false,"summary":null,"term":"GO:0051787"},{"annotations":[76454],"is_not":false,"summary":null,"term":"GO:0001018"},{"annotations":[72081],"is_not":false,"summary":null,"term":"GO:0097177"},{"annotations":[73016,73737],"is_not":false,"summary":null,"term":"GO:0030943"},{"annotations":[71136,71174,72169,72589,74093,74211,74341,75184,76271,76788,78351],"is_not":false,"summary":null,"term":"GO:0060090"},{"annotations":[73277],"is_not":false,"summary":null,"term":"GO:0008324"},{"annotations":[70406,70835,76819],"is_not":false,"summary":null,"term":"GO:0048029"},{"annotations":[75737,77429,77724,78073],"is_not":false,"summary":null,"term":"GO:0035925"},{"annotations":[70850,75682,77084],"is_not":false,"summary":null,"term":"GO:0003730"},{"annotations":[72868],"is_not":false,"summary":null,"term":"GO:0034353"},{"annotations":[70098,70107,70197,70279,70547,70843,71555,71602,71752,71836,72051,72097,72149,72412,72517,72543,72967,73075,73247,73286,73519,73543,73727,73911,74015,74456,74555,74635,74774,74936,75002,75205,75278,75325,75493,75815,75873,76335,76371,76775,76992,77421,77548,77693,77849,77909,77924,78104],"is_not":false,"summary":null,"term":"GO:0003729"},{"annotations":[74765],"is_not":false,"summary":null,"term":"GO:0004484"},{"annotations":[72088,72783],"is_not":false,"summary":null,"term":"GO:0005366"},{"annotations":[71748,78575],"is_not":false,"summary":null,"term":"GO:0032036"},{"annotations":[71438],"is_not":false,"summary":null,"term":"GO:0003942"},{"annotations":[74458],"is_not":false,"summary":null,"term":"GO:0004577"},{"annotations":[70791],"is_not":false,"summary":null,"term":"GO:0000225"},{"annotations":[70627],"is_not":false,"summary":null,"term":"GO:0008080"},{"annotations":[73393],"is_not":false,"summary":null,"term":"GO:0016410"},{"annotations":[76350],"is_not":false,"summary":null,"term":"GO:0071885"},{"annotations":[76094],"is_not":false,"summary":null,"term":"GO:0004018"},{"annotations":[74890],"is_not":false,"summary":null,"term":"GO:0051724"},{"annotations":[70967,72325,76347],"is_not":false,"summary":null,"term":"GO:0070403"},{"annotations":[71227,76882,78450],"is_not":false,"summary":null,"term":"GO:0003951"},{"annotations":[76470],"is_not":false,"summary":null,"term":"GO:0003952"},{"annotations":[76348],"is_not":false,"summary":null,"term":"GO:0046970"},{"annotations":[72236],"is_not":false,"summary":null,"term":"GO:0035529"},{"annotations":[73267],"is_not":false,"summary":null,"term":"GO:0052856"},{"annotations":[71142,78847],"is_not":false,"summary":null,"term":"GO:0050661"},{"annotations":[73775],"is_not":false,"summary":null,"term":"GO:0070402"},{"annotations":[76195],"is_not":false,"summary":null,"term":"GO:0003958"},{"annotations":[73773],"is_not":false,"summary":null,"term":"GO:0003960"},{"annotations":[71533,78322],"is_not":false,"summary":null,"term":"GO:0019781"},{"annotations":[71086,74168],"is_not":false,"summary":null,"term":"GO:0000309"},{"annotations":[78526],"is_not":false,"summary":null,"term":"GO:0004516"},{"annotations":[74169],"is_not":false,"summary":null,"term":"GO:0004515"},{"annotations":[71640],"is_not":false,"summary":null,"term":"GO:0005049"},{"annotations":[71145,72534,72670,73346,73359,74419,75464,76714],"is_not":false,"summary":null,"term":"GO:0061608"},{"annotations":[72530,73342,73355,74415,75017,75460,76710,77486],"is_not":false,"summary":null,"term":"GO:0008139"},{"annotations":[75536],"is_not":false,"summary":null,"term":"GO:0004518"},{"annotations":[77129],"is_not":false,"summary":null,"term":"GO:0015205"},{"annotations":[70958,75229],"is_not":false,"summary":null,"term":"GO:0004550"},{"annotations":[70996],"is_not":false,"summary":null,"term":"GO:0047429"},{"annotations":[73300,76083,76492],"is_not":false,"summary":null,"term":"GO:0031491"},{"annotations":[74932],"is_not":false,"summary":null,"term":"GO:0008374"},{"annotations":[78288],"is_not":false,"summary":null,"term":"GO:0004648"},{"annotations":[72206],"is_not":false,"summary":null,"term":"GO:0050152"},{"annotations":[77262],"is_not":false,"summary":null,"term":"GO:0004587"},{"annotations":[77345],"is_not":false,"summary":null,"term":"GO:0004585"},{"annotations":[75029],"is_not":false,"summary":null,"term":"GO:0004586"},{"annotations":[73121],"is_not":false,"summary":null,"term":"GO:0004588"},{"annotations":[73602],"is_not":false,"summary":null,"term":"GO:0004590"},{"annotations":[73192],"is_not":false,"summary":null,"term":"GO:0032357"},{"annotations":[70456,71075,71561,72115,75519,76232,76364,78446],"is_not":false,"summary":null,"term":"GO:0016491"},{"annotations":[76113],"is_not":false,"summary":null,"term":"GO:0016651"},{"annotations":[77853,77995],"is_not":false,"summary":null,"term":"GO:0050664"},{"annotations":[70765],"is_not":false,"summary":null,"term":"GO:0016616"},{"annotations":[70544],"is_not":false,"summary":null,"term":"GO:0004591"},{"annotations":[71003,72037],"is_not":false,"summary":null,"term":"GO:0008142"},{"annotations":[71712,78691],"is_not":false,"summary":null,"term":"GO:0005388"},{"annotations":[76767],"is_not":false,"summary":null,"term":"GO:0043682"},{"annotations":[70998],"is_not":false,"summary":null,"term":"GO:0015662"},{"annotations":[71014,72983,76458],"is_not":false,"summary":null,"term":"GO:0008553"},{"annotations":[73197],"is_not":false,"summary":null,"term":"GO:0008554"},{"annotations":[70470],"is_not":false,"summary":null,"term":"GO:0008474"},{"annotations":[72276],"is_not":false,"summary":null,"term":"GO:0004592"},{"annotations":[78811],"is_not":false,"summary":null,"term":"GO:0004594"},{"annotations":[72375],"is_not":false,"summary":null,"term":"GO:0015233"},{"annotations":[70903,74713,76013,77746],"is_not":false,"summary":null,"term":"GO:0016504"},{"annotations":[72246,76859],"is_not":false,"summary":null,"term":"GO:0004596"},{"annotations":[72765],"is_not":false,"summary":null,"term":"GO:0042277"},{"annotations":[76496],"is_not":false,"summary":null,"term":"GO:1990190"},{"annotations":[73869,76495],"is_not":false,"summary":null,"term":"GO:1990189"},{"annotations":[70490,71681,72015,72604,74734,74752,75112,75308,75478,76864,76869,76939,78616],"is_not":false,"summary":null,"term":"GO:0003755"},{"annotations":[73293],"is_not":false,"summary":null,"term":"GO:0005052"},{"annotations":[70914],"is_not":false,"summary":null,"term":"GO:0005053"},{"annotations":[76586,77491,77706],"is_not":false,"summary":null,"term":"GO:0004826"},{"annotations":[71230,73383,78420],"is_not":false,"summary":null,"term":"GO:0016791"},{"annotations":[72821],"is_not":false,"summary":null,"term":"GO:0019902"},{"annotations":[71934],"is_not":false,"summary":null,"term":"GO:0015114"},{"annotations":[78673],"is_not":false,"summary":null,"term":"GO:0004605"},{"annotations":[71374,75503,76057],"is_not":false,"summary":null,"term":"GO:0008195"},{"annotations":[70401],"is_not":false,"summary":null,"term":"GO:1990050"},{"annotations":[70180],"is_not":false,"summary":null,"term":"GO:0031210"},{"annotations":[70739],"is_not":false,"summary":null,"term":"GO:0008429"},{"annotations":[77011],"is_not":false,"summary":null,"term":"GO:0004608"},{"annotations":[71995,73614,76562,77166],"is_not":false,"summary":null,"term":"GO:0035091"},{"annotations":[72542],"is_not":false,"summary":null,"term":"GO:0050185"},{"annotations":[76358],"is_not":false,"summary":null,"term":"GO:0017176"},{"annotations":[72635],"is_not":false,"summary":null,"term":"GO:0004435"},{"annotations":[75795],"is_not":false,"summary":null,"term":"GO:0008526"},{"annotations":[77471],"is_not":false,"summary":null,"term":"GO:0016314"},{"annotations":[73419,73511,74551],"is_not":false,"summary":null,"term":"GO:0043813"},{"annotations":[71851,73372,78553],"is_not":false,"summary":null,"term":"GO:0080025"},{"annotations":[70716,71850,72910,73371,78552],"is_not":false,"summary":null,"term":"GO:0032266"},{"annotations":[73508,74548,74726],"is_not":false,"summary":null,"term":"GO:0004439"},{"annotations":[73403],"is_not":false,"summary":null,"term":"GO:0005546"},{"annotations":[76623],"is_not":false,"summary":null,"term":"GO:0070273"},{"annotations":[73498,77204],"is_not":false,"summary":null,"term":"GO:0043812"},{"annotations":[71194,77875],"is_not":false,"summary":null,"term":"GO:0004609"},{"annotations":[71035,72146],"is_not":false,"summary":null,"term":"GO:0004610"},{"annotations":[78535],"is_not":false,"summary":null,"term":"GO:0004604"},{"annotations":[75761],"is_not":false,"summary":null,"term":"GO:0089721"},{"annotations":[75821],"is_not":false,"summary":null,"term":"GO:0004614"},{"annotations":[78846],"is_not":false,"summary":null,"term":"GO:0004616"},{"annotations":[70972,75687,76310,77379],"is_not":false,"summary":null,"term":"GO:0004623"},{"annotations":[75053,77000],"is_not":false,"summary":null,"term":"GO:0004620"},{"annotations":[73964],"is_not":false,"summary":null,"term":"GO:0004630"},{"annotations":[78711],"is_not":false,"summary":null,"term":"GO:0005543"},{"annotations":[72937],"is_not":false,"summary":null,"term":"GO:0017128"},{"annotations":[74116],"is_not":false,"summary":null,"term":"GO:0046027"},{"annotations":[70508,73615,73659],"is_not":false,"summary":null,"term":"GO:0008972"},{"annotations":[73926],"is_not":false,"summary":null,"term":"GO:0004631"},{"annotations":[77399],"is_not":false,"summary":null,"term":"GO:0004632"},{"annotations":[73223],"is_not":false,"summary":null,"term":"GO:0008973"},{"annotations":[71822],"is_not":false,"summary":null,"term":"GO:0004721"},{"annotations":[76827],"is_not":false,"summary":null,"term":"GO:0000155"},{"annotations":[70855],"is_not":false,"summary":null,"term":"GO:0004637"},{"annotations":[70142],"is_not":false,"summary":null,"term":"GO:0004643"},{"annotations":[76137],"is_not":false,"summary":null,"term":"GO:0004639"},{"annotations":[78127],"is_not":false,"summary":null,"term":"GO:0004640"},{"annotations":[70856],"is_not":false,"summary":null,"term":"GO:0004641"},{"annotations":[70202],"is_not":false,"summary":null,"term":"GO:0004642"},{"annotations":[71573],"is_not":false,"summary":null,"term":"GO:0004644"},{"annotations":[70692,78503],"is_not":false,"summary":null,"term":"GO:0008081"},{"annotations":[73499,74945,75280,76694,77671],"is_not":false,"summary":null,"term":"GO:0008574"},{"annotations":[71368,72424,73817,76485,77701],"is_not":false,"summary":null,"term":"GO:0004535"},{"annotations":[72110],"is_not":false,"summary":null,"term":"GO:0008187"},{"annotations":[70798],"is_not":false,"summary":null,"term":"GO:0046403"},{"annotations":[71476],"is_not":false,"summary":null,"term":"GO:0051731"},{"annotations":[78193],"is_not":false,"summary":null,"term":"GO:0004651"},{"annotations":[74003],"is_not":false,"summary":null,"term":"GO:0002094"},{"annotations":[70864,74874,75172],"is_not":false,"summary":null,"term":"GO:0031593"},{"annotations":[71697],"is_not":false,"summary":null,"term":"GO:0004655"},{"annotations":[78663],"is_not":false,"summary":null,"term":"GO:0015386"},{"annotations":[72113,75782],"is_not":false,"summary":null,"term":"GO:0030628"},{"annotations":[78133],"is_not":false,"summary":null,"term":"GO:0030627"},{"annotations":[76380,76855],"is_not":false,"summary":null,"term":"GO:0036002"},{"annotations":[75459],"is_not":false,"summary":null,"term":"GO:0097157"},{"annotations":[75896],"is_not":false,"summary":null,"term":"GO:0043115"},{"annotations":[76886],"is_not":false,"summary":null,"term":"GO:0004664"},{"annotations":[71034],"is_not":false,"summary":null,"term":"GO:1990275"},{"annotations":[70569],"is_not":false,"summary":null,"term":"GO:0004657"},{"annotations":[70823,76319],"is_not":false,"summary":null,"term":"GO:0004827"},{"annotations":[70908,71702,73699,73757,74718,75177,75711,76018,76427,76973,77101,77751],"is_not":false,"summary":null,"term":"GO:0070628"},{"annotations":[78873],"is_not":false,"summary":null,"term":"GO:0019702"},{"annotations":[75444],"is_not":false,"summary":null,"term":"GO:0018423"},{"annotations":[74897],"is_not":false,"summary":null,"term":"GO:0004671"},{"annotations":[70514,72659],"is_not":false,"summary":null,"term":"GO:0003756"},{"annotations":[71424,73340],"is_not":false,"summary":null,"term":"GO:0004660"},{"annotations":[70493],"is_not":false,"summary":null,"term":"GO:0044183"},{"annotations":[71044],"is_not":false,"summary":null,"term":"GO:0034236"},{"annotations":[70429,70630,72163,72747,77289],"is_not":false,"summary":null,"term":"GO:0030295"},{"annotations":[70803],"is_not":false,"summary":null,"term":"GO:0004672"},{"annotations":[72714],"is_not":false,"summary":null,"term":"GO:0072542"},{"annotations":[70389],"is_not":false,"summary":null,"term":"GO:0004864"},{"annotations":[74739,74954],"is_not":false,"summary":null,"term":"GO:0043539"},{"annotations":[70196,70498,70513,71079,71170,71292,71345,71365,71568,71626,71634,72143,72278,72281,72385,72440,72569,72888,72954,73061,73236,73452,73566,73705,74222,74660,74690,74703,74833,75276,75381,75427,75491,75589,75697,75712,76153,76257,76278,76416,76430,76487,76568,76688,76708,76823,77016,77324,77350,77582,77727,77819,77965,77978,78135,78159,78297,78639,78654,78689,78807,78812],"is_not":false,"summary":null,"term":"GO:0004674"},{"annotations":[72818,72827,72838,73274,73634,73962,74173,74451,77931,78071],"is_not":false,"summary":null,"term":"GO:0004722"},{"annotations":[74277,75265],"is_not":false,"summary":null,"term":"GO:0004865"},{"annotations":[70571,70762,72601,75079,75143,78325,78886],"is_not":false,"summary":null,"term":"GO:0031386"},{"annotations":[70221,72990,73013,73395,73735,77568],"is_not":false,"summary":null,"term":"GO:0008320"},{"annotations":[70787,71293,77406],"is_not":false,"summary":null,"term":"GO:0004713"},{"annotations":[71683,75114],"is_not":false,"summary":null,"term":"GO:0008160"},{"annotations":[71886,72828,73262],"is_not":false,"summary":null,"term":"GO:0004725"},{"annotations":[71217],"is_not":false,"summary":null,"term":"GO:0008330"},{"annotations":[71149,72674,74517],"is_not":false,"summary":null,"term":"GO:0019706"},{"annotations":[76768,77246,78682],"is_not":false,"summary":null,"term":"GO:0015035"},{"annotations":[70344,70495,71743,72648,74280,75603,75707,76539,77791,77923],"is_not":false,"summary":null,"term":"GO:0051087"},{"annotations":[72086,73360,74486,75071,76773,77326,77356],"is_not":false,"summary":null,"term":"GO:0016279"},{"annotations":[77212,77357,77540,77903,78223,78776],"is_not":false,"summary":null,"term":"GO:0030674"},{"annotations":[72658,78897],"is_not":false,"summary":null,"term":"GO:0043495"},{"annotations":[77686],"is_not":false,"summary":null,"term":"GO:0008418"},{"annotations":[77419,77688],"is_not":false,"summary":null,"term":"GO:0070773"},{"annotations":[70210,70366,74931,76795,77068,77954],"is_not":false,"summary":null,"term":"GO:0046933"},{"annotations":[71321,77424,78245],"is_not":false,"summary":null,"term":"GO:0046961"},{"annotations":[72700,74942,77340,78825],"is_not":false,"summary":null,"term":"GO:0009982"},{"annotations":[74671],"is_not":false,"summary":null,"term":"GO:0008477"},{"annotations":[77808],"is_not":false,"summary":null,"term":"GO:0004731"},{"annotations":[73186],"is_not":false,"summary":null,"term":"GO:0000701"},{"annotations":[70677],"is_not":false,"summary":null,"term":"GO:0015489"},{"annotations":[74639,76933],"is_not":false,"summary":null,"term":"GO:0008478"},{"annotations":[70206,70746,72153,72340,73143,73666,74020,77261,78090,78286],"is_not":false,"summary":null,"term":"GO:0030170"},{"annotations":[75054],"is_not":false,"summary":null,"term":"GO:0004733"},{"annotations":[77936],"is_not":false,"summary":null,"term":"GO:0015218"},{"annotations":[76837],"is_not":false,"summary":null,"term":"GO:0004735"},{"annotations":[72836],"is_not":false,"summary":null,"term":"GO:0004736"},{"annotations":[71283,71737,73528],"is_not":false,"summary":null,"term":"GO:0004737"},{"annotations":[72453,77821],"is_not":false,"summary":null,"term":"GO:0004739"},{"annotations":[78247],"is_not":false,"summary":null,"term":"GO:0004743"},{"annotations":[76173],"is_not":false,"summary":null,"term":"GO:0050833"},{"annotations":[71205],"is_not":false,"summary":null,"term":"GO:0048038"},{"annotations":[75431],"is_not":false,"summary":null,"term":"GO:0005093"},{"annotations":[73489,77607],"is_not":false,"summary":null,"term":"GO:0004663"},{"annotations":[72299,73958],"is_not":false,"summary":null,"term":"GO:0000182"},{"annotations":[72513],"is_not":false,"summary":null,"term":"GO:0008531"},{"annotations":[76101],"is_not":false,"summary":null,"term":"GO:0042602"},{"annotations":[75656],"is_not":false,"summary":null,"term":"GO:0004746"},{"annotations":[71271],"is_not":false,"summary":null,"term":"GO:0000171"},{"annotations":[71274],"is_not":false,"summary":null,"term":"GO:0004526"},{"annotations":[75332],"is_not":false,"summary":null,"term":"GO:0033204"},{"annotations":[70994],"is_not":false,"summary":null,"term":"GO:0017111"},{"annotations":[71884],"is_not":false,"summary":null,"term":"GO:0004748"},{"annotations":[71881],"is_not":false,"summary":null,"term":"GO:0008998"},{"annotations":[72399,73516],"is_not":false,"summary":null,"term":"GO:0004749"},{"annotations":[74070],"is_not":false,"summary":null,"term":"GO:0004751"},{"annotations":[71435,73067,75773,75791,78191],"is_not":false,"summary":null,"term":"GO:0043023"},{"annotations":[73988,76754],"is_not":false,"summary":null,"term":"GO:0043024"},{"annotations":[72995,73400,76144,76357,77251,78593,78862],"is_not":false,"summary":null,"term":"GO:0043022"},{"annotations":[73720,74201,78333],"is_not":false,"summary":null,"term":"GO:0000340"},{"annotations":[70232,70346,70350,70367,70474,70486,70590,71259,71295,71367,71375,71400,71687,71728,71876,72000,72019,72207,72342,72717,72753,72776,72788,72845,72871,73129,73138,73152,73386,73410,73593,73623,73691,73783,73812,73861,73864,73937,73970,73985,74103,74139,74240,74401,74469,74490,74642,74691,74697,74706,74783,74848,74851,75009,75015,75343,75530,75535,75604,75743,75826,75831,75916,75957,75980,76218,76442,76507,76559,76572,76802,76936,77176,77195,77226,77444,77462,77575,78115,78706],"is_not":false,"summary":null,"term":"GO:0003723"},{"annotations":[70696,75032],"is_not":false,"summary":null,"term":"GO:0000339"},{"annotations":[70445,72073,72343,75924,76822,78169],"is_not":false,"summary":null,"term":"GO:0004521"},{"annotations":[75673],"is_not":false,"summary":null,"term":"GO:0016891"},{"annotations":[70895,71877,71960,72020,73672,73765,74710,74868,74935,75050,75344,76089,77645,77766,77955,78381,78915],"is_not":false,"summary":null,"term":"GO:0003724"},{"annotations":[76791],"is_not":false,"summary":null,"term":"GO:0061632"},{"annotations":[76110],"is_not":false,"summary":null,"term":"GO:0008419"},{"annotations":[73440],"is_not":false,"summary":null,"term":"GO:0003972"},{"annotations":[76744],"is_not":false,"summary":null,"term":"GO:0070063"},{"annotations":[70436,71206,73843,74562,74955,75134,75160,75661,76028],"is_not":false,"summary":null,"term":"GO:0001054"},{"annotations":[77899],"is_not":false,"summary":null,"term":"GO:0001165"},{"annotations":[71649],"is_not":false,"summary":null,"term":"GO:0001042"},{"annotations":[75130],"is_not":false,"summary":null,"term":"GO:0001164"},{"annotations":[71650,72300],"is_not":false,"summary":null,"term":"GO:0001181"},{"annotations":[78459],"is_not":false,"summary":null,"term":"GO:0001179"},{"annotations":[78458],"is_not":false,"summary":null,"term":"GO:0001163"},{"annotations":[71207,72988,73994,74563,75055,75135,75662,76029,76946],"is_not":false,"summary":null,"term":"GO:0001055"},{"annotations":[72409,77128],"is_not":false,"summary":null,"term":"GO:1990269"},{"annotations":[70416,71818,72132,72807,72811,73163,73447,73484,73789,73870,74502,75156,75619,76737,77092,77229,77293,78124,78427,78443,78648],"is_not":false,"summary":null,"term":"GO:0000978"},{"annotations":[70546,71165,75607],"is_not":false,"summary":null,"term":"GO:0000993"},{"annotations":[75639,77234],"is_not":false,"summary":null,"term":"GO:0001139"},{"annotations":[78448],"is_not":false,"summary":null,"term":"GO:0008420"},{"annotations":[71350,71930,73982,74801,75962,76282,77614,78754,78889],"is_not":false,"summary":null,"term":"GO:0016251"},{"annotations":[75638,76198,77233],"is_not":false,"summary":null,"term":"GO:0000977"},{"annotations":[70437,71208,71447,73046,73844,74564,75136,75663,76030],"is_not":false,"summary":null,"term":"GO:0001056"},{"annotations":[73477],"is_not":false,"summary":null,"term":"GO:0000994"},{"annotations":[76636],"is_not":false,"summary":null,"term":"GO:0000995"},{"annotations":[70132],"is_not":false,"summary":null,"term":"GO:0001002"},{"annotations":[70133],"is_not":false,"summary":null,"term":"GO:0001003"},{"annotations":[76637],"is_not":false,"summary":null,"term":"GO:0001006"},{"annotations":[74305],"is_not":false,"summary":null,"term":"GO:0071164"},{"annotations":[78313,78543],"is_not":false,"summary":null,"term":"GO:0050265"},{"annotations":[75209,78835],"is_not":false,"summary":null,"term":"GO:0004523"},{"annotations":[76145],"is_not":false,"summary":null,"term":"GO:0016433"},{"annotations":[77584],"is_not":false,"summary":null,"term":"GO:0009383"},{"annotations":[74886],"is_not":false,"summary":null,"term":"GO:0070037"},{"annotations":[74836,75213,77541],"is_not":false,"summary":null,"term":"GO:0008650"},{"annotations":[78258],"is_not":false,"summary":null,"term":"GO:0070042"},{"annotations":[70281,71838,72172,72405,72545,73255,74882,76228,76286,77135],"is_not":false,"summary":null,"term":"GO:0019843"},{"annotations":[72104],"is_not":false,"summary":null,"term":"GO:1990883"},{"annotations":[73080],"is_not":false,"summary":null,"term":"GO:0008649"},{"annotations":[73296],"is_not":false,"summary":null,"term":"GO:0042134"},{"annotations":[75293,78646],"is_not":false,"summary":null,"term":"GO:0000095"},{"annotations":[75610],"is_not":false,"summary":null,"term":"GO:0008898"},{"annotations":[76770],"is_not":false,"summary":null,"term":"GO:0017061"},{"annotations":[75857],"is_not":false,"summary":null,"term":"GO:0046523"},{"annotations":[73796],"is_not":false,"summary":null,"term":"GO:0050278"},{"annotations":[73465],"is_not":false,"summary":null,"term":"GO:1990825"},{"annotations":[72161,73151],"is_not":false,"summary":null,"term":"GO:0070905"},{"annotations":[75972,77651],"is_not":false,"summary":null,"term":"GO:0004758"},{"annotations":[75357],"is_not":false,"summary":null,"term":"GO:0009001"},{"annotations":[72860,75902],"is_not":false,"summary":null,"term":"GO:0004828"},{"annotations":[74911,75631,78082],"is_not":false,"summary":null,"term":"GO:0004185"},{"annotations":[73922,74365,74891,75369,76404,78212],"is_not":false,"summary":null,"term":"GO:0004252"},{"annotations":[73656,73899],"is_not":false,"summary":null,"term":"GO:0015343"},{"annotations":[72389,78310],"is_not":false,"summary":null,"term":"GO:0005047"},{"annotations":[72993,73398],"is_not":false,"summary":null,"term":"GO:0005048"},{"annotations":[75199],"is_not":false,"summary":null,"term":"GO:0035591"},{"annotations":[72687,73879],"is_not":false,"summary":null,"term":"GO:0038023"},{"annotations":[70940],"is_not":false,"summary":null,"term":"GO:0005102"},{"annotations":[73684],"is_not":false,"summary":null,"term":"GO:0008310"},{"annotations":[72505],"is_not":false,"summary":null,"term":"GO:0045145"},{"annotations":[70246,70311,71159,71892,72193,72227,72573,72618,73030,73310,74153,74343,74392,74582,74681,74977,76400,77111],"is_not":false,"summary":null,"term":"GO:0003697"},{"annotations":[72072,78095],"is_not":false,"summary":null,"term":"GO:0000014"},{"annotations":[73031,73311,74154],"is_not":false,"summary":null,"term":"GO:0017116"},{"annotations":[70097,70869,72619,75672,76202],"is_not":false,"summary":null,"term":"GO:0003727"},{"annotations":[72045,73579,77191],"is_not":false,"summary":null,"term":"GO:0031267"},{"annotations":[71030,71113,76763],"is_not":false,"summary":null,"term":"GO:0070181"},{"annotations":[72029,72597,73532,75415,75729,76596,77020],"is_not":false,"summary":null,"term":"GO:0005484"},{"annotations":[71517,72027,73401,74226,74526,75072,75413,75480,76594,77299],"is_not":false,"summary":null,"term":"GO:0000149"},{"annotations":[71100,73021,74863,75258,75302,78119,78375,78771],"is_not":false,"summary":null,"term":"GO:0030515"},{"annotations":[75187],"is_not":false,"summary":null,"term":"GO:0017069"},{"annotations":[77029,78662],"is_not":false,"summary":null,"term":"GO:0015385"},{"annotations":[75584],"is_not":false,"summary":null,"term":"GO:0005483"},{"annotations":[74368],"is_not":false,"summary":null,"term":"GO:0004766"},{"annotations":[70678],"is_not":false,"summary":null,"term":"GO:0015606"},{"annotations":[78377],"is_not":false,"summary":null,"term":"GO:0000297"},{"annotations":[72418,73952],"is_not":false,"summary":null,"term":"GO:0042284"},{"annotations":[72415],"is_not":false,"summary":null,"term":"GO:0000170"},{"annotations":[76954,77841],"is_not":false,"summary":null,"term":"GO:0050291"},{"annotations":[78676],"is_not":false,"summary":null,"term":"GO:0042392"},{"annotations":[78768],"is_not":false,"summary":null,"term":"GO:0106166"},{"annotations":[76250],"is_not":false,"summary":null,"term":"GO:0004506"},{"annotations":[75366],"is_not":false,"summary":null,"term":"GO:0051996"},{"annotations":[74612],"is_not":false,"summary":null,"term":"GO:0004768"},{"annotations":[75559],"is_not":false,"summary":null,"term":"GO:0003838"},{"annotations":[76047],"is_not":false,"summary":null,"term":"GO:0032934"},{"annotations":[76048],"is_not":false,"summary":null,"term":"GO:0120015"},{"annotations":[71050,73169,74430,76779,77777],"is_not":false,"summary":null,"term":"GO:0005200"},{"annotations":[70749,72449,72682,73230,73965,74543,74900,75016,75469,76234,76540,77484,78710,78732,78838],"is_not":false,"summary":null,"term":"GO:0017056"},{"annotations":[70280,70317,70347,70487,70502,70582,70628,70991,71027,71199,71260,71267,71296,71401,71614,71772,71837,71924,71945,72001,72024,72066,72098,72181,72284,72367,72390,72544,72645,72693,72746,72869,73002,73057,73130,73139,73153,73193,73227,73287,73325,73437,73520,73750,73784,73801,73850,73876,73887,73890,73912,73991,74094,74140,74180,74212,74223,74271,74402,74470,74476,74618,74643,74692,74707,74855,75003,75082,75140,75216,75326,75562,75698,75721,75744,75767,75832,75917,76219,76285,76443,76613,76760,76825,76968,77046,77077,77160,77163,77177,77196,77288,77296,77463,77661,77799,77925,77979,78234,78352,78416,78452,78520,78707,78853,78913],"is_not":false,"summary":null,"term":"GO:0003735"},{"annotations":[71385,72212,72651,72889,74174],"is_not":false,"summary":null,"term":"GO:0005198"},{"annotations":[75224],"is_not":false,"summary":null,"term":"GO:0008177"},{"annotations":[71776,74918],"is_not":false,"summary":null,"term":"GO:0004775"},{"annotations":[75304,76665],"is_not":false,"summary":null,"term":"GO:0004777"},{"annotations":[75913],"is_not":false,"summary":null,"term":"GO:0004575"},{"annotations":[75048],"is_not":false,"summary":null,"term":"GO:0008506"},{"annotations":[76875],"is_not":false,"summary":null,"term":"GO:0004781"},{"annotations":[73548],"is_not":false,"summary":null,"term":"GO:0015116"},{"annotations":[75522],"is_not":false,"summary":null,"term":"GO:0070224"},{"annotations":[75931],"is_not":false,"summary":null,"term":"GO:0032542"},{"annotations":[77173],"is_not":false,"summary":null,"term":"GO:0004783"},{"annotations":[74844],"is_not":false,"summary":null,"term":"GO:0019948"},{"annotations":[75091],"is_not":false,"summary":null,"term":"GO:0061656"},{"annotations":[72374,72382],"is_not":false,"summary":null,"term":"GO:0061665"},{"annotations":[74260],"is_not":false,"summary":null,"term":"GO:0070139"},{"annotations":[76187],"is_not":false,"summary":null,"term":"GO:0004784"},{"annotations":[70102,70161,74812,75583,75728,77019,78355],"is_not":false,"summary":null,"term":"GO:0019905"},{"annotations":[75384,76260,76419,76571],"is_not":false,"summary":null,"term":"GO:0050321"},{"annotations":[70754,71929,75131,75961,76280],"is_not":false,"summary":null,"term":"GO:0017025"},{"annotations":[75993],"is_not":false,"summary":null,"term":"GO:0010521"},{"annotations":[70927],"is_not":false,"summary":null,"term":"GO:0070034"},{"annotations":[70923],"is_not":false,"summary":null,"term":"GO:0003721"},{"annotations":[70612,70925,76104,77059],"is_not":false,"summary":null,"term":"GO:0042162"},{"annotations":[72188,78077],"is_not":false,"summary":null,"term":"GO:0004326"},{"annotations":[75472],"is_not":false,"summary":null,"term":"GO:0001097"},{"annotations":[71870],"is_not":false,"summary":null,"term":"GO:0001156"},{"annotations":[77005],"is_not":false,"summary":null,"term":"GO:0004788"},{"annotations":[73010],"is_not":false,"summary":null,"term":"GO:0030976"},{"annotations":[76180],"is_not":false,"summary":null,"term":"GO:0004789"},{"annotations":[70422,75126,78195],"is_not":false,"summary":null,"term":"GO:0008379"},{"annotations":[73025,78292],"is_not":false,"summary":null,"term":"GO:0004791"},{"annotations":[70119,74024],"is_not":false,"summary":null,"term":"GO:0004792"},{"annotations":[76683],"is_not":false,"summary":null,"term":"GO:0004794"},{"annotations":[76128],"is_not":false,"summary":null,"term":"GO:0004795"},{"annotations":[71092,73434],"is_not":false,"summary":null,"term":"GO:0004829"},{"annotations":[73944],"is_not":false,"summary":null,"term":"GO:0004298"},{"annotations":[70961],"is_not":false,"summary":null,"term":"GO:0004798"},{"annotations":[78330],"is_not":false,"summary":null,"term":"GO:0004799"},{"annotations":[72485],"is_not":false,"summary":null,"term":"GO:0019166"},{"annotations":[72876],"is_not":false,"summary":null,"term":"GO:0004801"},{"annotations":[71770,72052,72848,75700,78752],"is_not":false,"summary":null,"term":"GO:0000976"},{"annotations":[73098,74731,76025,76632,77220],"is_not":false,"summary":null,"term":"GO:0003713"},{"annotations":[71900,76440,76678,76742,78176],"is_not":false,"summary":null,"term":"GO:0003712"},{"annotations":[73379,77858],"is_not":false,"summary":null,"term":"GO:0003714"},{"annotations":[72303],"is_not":false,"summary":null,"term":"GO:0003711"},{"annotations":[73860,73969],"is_not":false,"summary":null,"term":"GO:0001147"},{"annotations":[78254],"is_not":false,"summary":null,"term":"GO:0004802"},{"annotations":[72726,73264,76139,78568],"is_not":false,"summary":null,"term":"GO:0003746"},{"annotations":[71418,72119,72413,73557,73721,73907,73986,74202,74556,75010,75714,76355,76660,77524,77763,78748],"is_not":false,"summary":null,"term":"GO:0003743"},{"annotations":[71557,72121,72623,73909,78750],"is_not":false,"summary":null,"term":"GO:0031369"},{"annotations":[72221],"is_not":false,"summary":null,"term":"GO:0003747"},{"annotations":[73461],"is_not":false,"summary":null,"term":"GO:0016149"},{"annotations":[70137,70296,70952,71202,74533,74810,75065,75525,76365],"is_not":false,"summary":null,"term":"GO:0022857"},{"annotations":[73590,74013,75263,77775,78045,78495],"is_not":false,"summary":null,"term":"GO:0004805"},{"annotations":[71618],"is_not":false,"summary":null,"term":"GO:0005371"},{"annotations":[71490],"is_not":false,"summary":null,"term":"GO:0004806"},{"annotations":[71825],"is_not":false,"summary":null,"term":"GO:0042937"},{"annotations":[73636],"is_not":false,"summary":null,"term":"GO:0008240"},{"annotations":[77933],"is_not":false,"summary":null,"term":"GO:0052735"},{"annotations":[70720,78014],"is_not":false,"summary":null,"term":"GO:0016428"},{"annotations":[71427],"is_not":false,"summary":null,"term":"GO:0008176"},{"annotations":[73384],"is_not":false,"summary":null,"term":"GO:0000215"},{"annotations":[70719,71805,72092,72101,72176,72857,73063,73351,75900,76420,77599,78013,78275],"is_not":false,"summary":null,"term":"GO:0000049"},{"annotations":[71110],"is_not":false,"summary":null,"term":"GO:0052381"},{"annotations":[73044],"is_not":false,"summary":null,"term":"GO:0008193"},{"annotations":[72135,73416],"is_not":false,"summary":null,"term":"GO:0008175"},{"annotations":[78775],"is_not":false,"summary":null,"term":"GO:0061503"},{"annotations":[72663],"is_not":false,"summary":null,"term":"GO:0008479"},{"annotations":[71582,72607,77717],"is_not":false,"summary":null,"term":"GO:0000213"},{"annotations":[71751],"is_not":false,"summary":null,"term":"GO:0043829"},{"annotations":[73245],"is_not":false,"summary":null,"term":"GO:0004834"},{"annotations":[70379,71601],"is_not":false,"summary":null,"term":"GO:0004830"},{"annotations":[70987,77516],"is_not":false,"summary":null,"term":"GO:0004831"},{"annotations":[72970,75455,75905],"is_not":false,"summary":null,"term":"GO:0030619"},{"annotations":[70525],"is_not":false,"summary":null,"term":"GO:1990446"},{"annotations":[75456,76382],"is_not":false,"summary":null,"term":"GO:0030620"},{"annotations":[73857,75125,76908,77139],"is_not":false,"summary":null,"term":"GO:0034511"},{"annotations":[71721],"is_not":false,"summary":null,"term":"GO:0030621"},{"annotations":[75457,78066],"is_not":false,"summary":null,"term":"GO:0030623"},{"annotations":[71719,71758,75452,76376,76851],"is_not":false,"summary":null,"term":"GO:0017070"},{"annotations":[73551],"is_not":false,"summary":null,"term":"GO:0004839"},{"annotations":[71916,71994,72741,73424,73761,75176,75829,76412,76759,77313,77339,77798,78462],"is_not":false,"summary":null,"term":"GO:0043130"},{"annotations":[71485,77065],"is_not":false,"summary":null,"term":"GO:0061631"},{"annotations":[73644,73680,76651],"is_not":false,"summary":null,"term":"GO:0031624"},{"annotations":[75727,77839,77882,78558,78822],"is_not":false,"summary":null,"term":"GO:1990757"},{"annotations":[71342,71875,71953,72091,72917,73648,73808,73827,74773,74790,74899,75614,75774,76326,76655,77252,77604,78021,78600],"is_not":false,"summary":null,"term":"GO:0061630"},{"annotations":[70572,72602,73008,75080,77358,77795,77904,78224,78326,78887],"is_not":false,"summary":null,"term":"GO:0031625"},{"annotations":[73681],"is_not":false,"summary":null,"term":"GO:0032182"},{"annotations":[74200],"is_not":false,"summary":null,"term":"GO:0034450"},{"annotations":[70729,75518],"is_not":false,"summary":null,"term":"GO:0045134"},{"annotations":[74334,75267],"is_not":false,"summary":null,"term":"GO:0005459"},{"annotations":[70808,72627,73490],"is_not":false,"summary":null,"term":"GO:0003978"},{"annotations":[75268],"is_not":false,"summary":null,"term":"GO:0005460"},{"annotations":[78107],"is_not":false,"summary":null,"term":"GO:0003980"},{"annotations":[72467],"is_not":false,"summary":null,"term":"GO:0008108"},{"annotations":[75878],"is_not":false,"summary":null,"term":"GO:0003977"},{"annotations":[76730],"is_not":false,"summary":null,"term":"GO:0005462"},{"annotations":[78868],"is_not":false,"summary":null,"term":"GO:0033862"},{"annotations":[70113,70343,70494,71185,71742,72522,73392,73842,73906,74631,75324,75387,75814,76824,76924,77239,77481,77790,77922,78110,78211,78405,78791],"is_not":false,"summary":null,"term":"GO:0051082"},{"annotations":[77149],"is_not":false,"summary":null,"term":"GO:0004844"},{"annotations":[73240],"is_not":false,"summary":null,"term":"GO:0004846"},{"annotations":[70676],"is_not":false,"summary":null,"term":"GO:0015204"},{"annotations":[73946],"is_not":false,"summary":null,"term":"GO:0050385"},{"annotations":[77647],"is_not":false,"summary":null,"term":"GO:0004849"},{"annotations":[74027],"is_not":false,"summary":null,"term":"GO:0042292"},{"annotations":[71532],"is_not":false,"summary":null,"term":"GO:0004851"},{"annotations":[74243],"is_not":false,"summary":null,"term":"GO:0004853"},{"annotations":[74332],"is_not":false,"summary":null,"term":"GO:0004852"},{"annotations":[70166,70443],"is_not":false,"summary":null,"term":"GO:0004832"},{"annotations":[71622],"is_not":false,"summary":null,"term":"GO:0008308"},{"annotations":[78546],"is_not":false,"summary":null,"term":"GO:0042907"},{"annotations":[74805],"is_not":false,"summary":null,"term":"GO:0000403"},{"annotations":[70144,70373,71312,71518,71695,72152,72644,72761,72839,73142,74527,74609,75481,76031,76054,77072,77300,77657],"is_not":false,"summary":null,"term":"GO:0008270"},{"annotations":[74147,77188],"is_not":false,"summary":null,"term":"GO:0005385"}]},"doi":"10.1093/bib/bbr042","gene_count":2630,"genes_by_uniquename":{"SJAG_00004":null,"SJAG_00018":null,"SJAG_00027":null,"SJAG_00029":null,"SJAG_00030":null,"SJAG_00031":null,"SJAG_00033":null,"SJAG_00034":null,"SJAG_00035":null,"SJAG_00038":null,"SJAG_00039":null,"SJAG_00040":null,"SJAG_00043":null,"SJAG_00044":null,"SJAG_00048":null,"SJAG_00052":null,"SJAG_00054":null,"SJAG_00057":null,"SJAG_00058":null,"SJAG_00059":null,"SJAG_00063":null,"SJAG_00065":null,"SJAG_00066":null,"SJAG_00067":null,"SJAG_00070":null,"SJAG_00071":null,"SJAG_00072":null,"SJAG_00073":null,"SJAG_00074":null,"SJAG_00076":null,"SJAG_00078":null,"SJAG_00081":null,"SJAG_00082":null,"SJAG_00084":null,"SJAG_00085":null,"SJAG_00086":null,"SJAG_00087":null,"SJAG_00088":null,"SJAG_00091":null,"SJAG_00093":null,"SJAG_00094":null,"SJAG_00099":null,"SJAG_00102":null,"SJAG_00103":null,"SJAG_00106":null,"SJAG_00107":null,"SJAG_00108":null,"SJAG_00109":null,"SJAG_00111":null,"SJAG_00114":null,"SJAG_00115":null,"SJAG_00116":null,"SJAG_00118":null,"SJAG_00119":null,"SJAG_00120":null,"SJAG_00125":null,"SJAG_00126":null,"SJAG_00129":null,"SJAG_00133":null,"SJAG_00134":null,"SJAG_00135":null,"SJAG_00136":null,"SJAG_00142":null,"SJAG_00143":null,"SJAG_00147":null,"SJAG_00149":null,"SJAG_00150":null,"SJAG_00154":null,"SJAG_00155":null,"SJAG_00159":null,"SJAG_00163":null,"SJAG_00164":null,"SJAG_00166":null,"SJAG_00168":null,"SJAG_00169":null,"SJAG_00170":null,"SJAG_00175":null,"SJAG_00178":null,"SJAG_00181":null,"SJAG_00182":null,"SJAG_00183":null,"SJAG_00184":null,"SJAG_00185":null,"SJAG_00186":null,"SJAG_00188":null,"SJAG_00195":null,"SJAG_00196":null,"SJAG_00197":null,"SJAG_00198":null,"SJAG_00199":null,"SJAG_00202":null,"SJAG_00204":null,"SJAG_00209":null,"SJAG_00211":null,"SJAG_00212":null,"SJAG_00214":null,"SJAG_00218":null,"SJAG_00220":null,"SJAG_00221":null,"SJAG_00222":null,"SJAG_00224":null,"SJAG_00225":null,"SJAG_00228":null,"SJAG_00229":null,"SJAG_00231":null,"SJAG_00232":null,"SJAG_00233":null,"SJAG_00234":null,"SJAG_00236":null,"SJAG_00237":null,"SJAG_00242":null,"SJAG_00243":null,"SJAG_00244":null,"SJAG_00245":null,"SJAG_00246":null,"SJAG_00248":null,"SJAG_00252":null,"SJAG_00253":null,"SJAG_00254":null,"SJAG_00255":null,"SJAG_00256":null,"SJAG_00259":null,"SJAG_00261":null,"SJAG_00265":null,"SJAG_00266":null,"SJAG_00271":null,"SJAG_00272":null,"SJAG_00275":null,"SJAG_00276":null,"SJAG_00277":null,"SJAG_00278":null,"SJAG_00281":null,"SJAG_00283":null,"SJAG_00285":null,"SJAG_00287":null,"SJAG_00288":null,"SJAG_00293":null,"SJAG_00295":null,"SJAG_00296":null,"SJAG_00299":null,"SJAG_00300":null,"SJAG_00301":null,"SJAG_00303":null,"SJAG_00305":null,"SJAG_00306":null,"SJAG_00307":null,"SJAG_00309":null,"SJAG_00310":null,"SJAG_00311":null,"SJAG_00312":null,"SJAG_00313":null,"SJAG_00315":null,"SJAG_00319":null,"SJAG_00321":null,"SJAG_00322":null,"SJAG_00323":null,"SJAG_00324":null,"SJAG_00325":null,"SJAG_00326":null,"SJAG_00328":null,"SJAG_00329":null,"SJAG_00331":null,"SJAG_00332":null,"SJAG_00333":null,"SJAG_00334":null,"SJAG_00337":null,"SJAG_00338":null,"SJAG_00339":null,"SJAG_00341":null,"SJAG_00342":null,"SJAG_00344":null,"SJAG_00349":null,"SJAG_00354":null,"SJAG_00355":null,"SJAG_00356":null,"SJAG_00357":null,"SJAG_00358":null,"SJAG_00359":null,"SJAG_00364":null,"SJAG_00369":null,"SJAG_00370":null,"SJAG_00375":null,"SJAG_00376":null,"SJAG_00378":null,"SJAG_00380":null,"SJAG_00381":null,"SJAG_00384":null,"SJAG_00390":null,"SJAG_00391":null,"SJAG_00392":null,"SJAG_00394":null,"SJAG_00395":null,"SJAG_00396":null,"SJAG_00402":null,"SJAG_00403":null,"SJAG_00405":null,"SJAG_00409":null,"SJAG_00410":null,"SJAG_00412":null,"SJAG_00413":null,"SJAG_00414":null,"SJAG_00416":null,"SJAG_00420":null,"SJAG_00421":null,"SJAG_00424":null,"SJAG_00425":null,"SJAG_00426":null,"SJAG_00427":null,"SJAG_00428":null,"SJAG_00430":null,"SJAG_00432":null,"SJAG_00434":null,"SJAG_00435":null,"SJAG_00436":null,"SJAG_00437":null,"SJAG_00438":null,"SJAG_00439":null,"SJAG_00442":null,"SJAG_00443":null,"SJAG_00444":null,"SJAG_00445":null,"SJAG_00446":null,"SJAG_00447":null,"SJAG_00450":null,"SJAG_00452":null,"SJAG_00453":null,"SJAG_00457":null,"SJAG_00459":null,"SJAG_00464":null,"SJAG_00466":null,"SJAG_00469":null,"SJAG_00470":null,"SJAG_00471":null,"SJAG_00474":null,"SJAG_00475":null,"SJAG_00476":null,"SJAG_00480":null,"SJAG_00482":null,"SJAG_00486":null,"SJAG_00488":null,"SJAG_00490":null,"SJAG_00493":null,"SJAG_00495":null,"SJAG_00498":null,"SJAG_00499":null,"SJAG_00501":null,"SJAG_00502":null,"SJAG_00504":null,"SJAG_00505":null,"SJAG_00506":null,"SJAG_00507":null,"SJAG_00508":null,"SJAG_00509":null,"SJAG_00512":null,"SJAG_00513":null,"SJAG_00514":null,"SJAG_00516":null,"SJAG_00518":null,"SJAG_00519":null,"SJAG_00521":null,"SJAG_00523":null,"SJAG_00524":null,"SJAG_00526":null,"SJAG_00529":null,"SJAG_00530":null,"SJAG_00531":null,"SJAG_00532":null,"SJAG_00534":null,"SJAG_00536":null,"SJAG_00538":null,"SJAG_00541":null,"SJAG_00544":null,"SJAG_00547":null,"SJAG_00551":null,"SJAG_00553":null,"SJAG_00554":null,"SJAG_00557":null,"SJAG_00558":null,"SJAG_00559":null,"SJAG_00560":null,"SJAG_00562":null,"SJAG_00564":null,"SJAG_00567":null,"SJAG_00570":null,"SJAG_00571":null,"SJAG_00572":null,"SJAG_00576":null,"SJAG_00577":null,"SJAG_00579":null,"SJAG_00580":null,"SJAG_00581":null,"SJAG_00582":null,"SJAG_00585":null,"SJAG_00586":null,"SJAG_00587":null,"SJAG_00589":null,"SJAG_00591":null,"SJAG_00592":null,"SJAG_00593":null,"SJAG_00596":null,"SJAG_00597":null,"SJAG_00598":null,"SJAG_00599":null,"SJAG_00600":null,"SJAG_00601":null,"SJAG_00602":null,"SJAG_00604":null,"SJAG_00605":null,"SJAG_00609":null,"SJAG_00610":null,"SJAG_00612":null,"SJAG_00613":null,"SJAG_00615":null,"SJAG_00616":null,"SJAG_00618":null,"SJAG_00619":null,"SJAG_00620":null,"SJAG_00622":null,"SJAG_00623":null,"SJAG_00624":null,"SJAG_00626":null,"SJAG_00629":null,"SJAG_00630":null,"SJAG_00632":null,"SJAG_00633":null,"SJAG_00635":null,"SJAG_00636":null,"SJAG_00637":null,"SJAG_00638":null,"SJAG_00639":null,"SJAG_00643":null,"SJAG_00645":null,"SJAG_00649":null,"SJAG_00653":null,"SJAG_00657":null,"SJAG_00659":null,"SJAG_00660":null,"SJAG_00661":null,"SJAG_00663":null,"SJAG_00666":null,"SJAG_00667":null,"SJAG_00669":null,"SJAG_00673":null,"SJAG_00674":null,"SJAG_00677":null,"SJAG_00678":null,"SJAG_00682":null,"SJAG_00683":null,"SJAG_00684":null,"SJAG_00685":null,"SJAG_00686":null,"SJAG_00687":null,"SJAG_00689":null,"SJAG_00690":null,"SJAG_00691":null,"SJAG_00692":null,"SJAG_00693":null,"SJAG_00694":null,"SJAG_00695":null,"SJAG_00696":null,"SJAG_00698":null,"SJAG_00699":null,"SJAG_00700":null,"SJAG_00702":null,"SJAG_00704":null,"SJAG_00705":null,"SJAG_00706":null,"SJAG_00713":null,"SJAG_00714":null,"SJAG_00717":null,"SJAG_00718":null,"SJAG_00720":null,"SJAG_00722":null,"SJAG_00726":null,"SJAG_00727":null,"SJAG_00728":null,"SJAG_00729":null,"SJAG_00730":null,"SJAG_00731":null,"SJAG_00732":null,"SJAG_00734":null,"SJAG_00735":null,"SJAG_00738":null,"SJAG_00739":null,"SJAG_00744":null,"SJAG_00747":null,"SJAG_00748":null,"SJAG_00749":null,"SJAG_00750":null,"SJAG_00752":null,"SJAG_00754":null,"SJAG_00757":null,"SJAG_00758":null,"SJAG_00759":null,"SJAG_00760":null,"SJAG_00762":null,"SJAG_00763":null,"SJAG_00765":null,"SJAG_00767":null,"SJAG_00769":null,"SJAG_00772":null,"SJAG_00773":null,"SJAG_00776":null,"SJAG_00777":null,"SJAG_00778":null,"SJAG_00779":null,"SJAG_00784":null,"SJAG_00785":null,"SJAG_00786":null,"SJAG_00790":null,"SJAG_00794":null,"SJAG_00795":null,"SJAG_00798":null,"SJAG_00799":null,"SJAG_00800":null,"SJAG_00801":null,"SJAG_00802":null,"SJAG_00803":null,"SJAG_00808":null,"SJAG_00809":null,"SJAG_00810":null,"SJAG_00811":null,"SJAG_00813":null,"SJAG_00814":null,"SJAG_00815":null,"SJAG_00816":null,"SJAG_00820":null,"SJAG_00821":null,"SJAG_00822":null,"SJAG_00823":null,"SJAG_00825":null,"SJAG_00826":null,"SJAG_00830":null,"SJAG_00836":null,"SJAG_00837":null,"SJAG_00838":null,"SJAG_00839":null,"SJAG_00840":null,"SJAG_00841":null,"SJAG_00846":null,"SJAG_00847":null,"SJAG_00850":null,"SJAG_00853":null,"SJAG_00854":null,"SJAG_00857":null,"SJAG_00859":null,"SJAG_00861":null,"SJAG_00863":null,"SJAG_00865":null,"SJAG_00866":null,"SJAG_00870":null,"SJAG_00871":null,"SJAG_00874":null,"SJAG_00876":null,"SJAG_00878":null,"SJAG_00879":null,"SJAG_00880":null,"SJAG_00881":null,"SJAG_00882":null,"SJAG_00884":null,"SJAG_00886":null,"SJAG_00891":null,"SJAG_00894":null,"SJAG_00895":null,"SJAG_00897":null,"SJAG_00899":null,"SJAG_00900":null,"SJAG_00901":null,"SJAG_00902":null,"SJAG_00903":null,"SJAG_00904":null,"SJAG_00906":null,"SJAG_00907":null,"SJAG_00910":null,"SJAG_00911":null,"SJAG_00912":null,"SJAG_00914":null,"SJAG_00916":null,"SJAG_00920":null,"SJAG_00921":null,"SJAG_00923":null,"SJAG_00930":null,"SJAG_00936":null,"SJAG_00937":null,"SJAG_00938":null,"SJAG_00940":null,"SJAG_00941":null,"SJAG_00942":null,"SJAG_00943":null,"SJAG_00944":null,"SJAG_00945":null,"SJAG_00946":null,"SJAG_00947":null,"SJAG_00949":null,"SJAG_00950":null,"SJAG_00954":null,"SJAG_00955":null,"SJAG_00956":null,"SJAG_00957":null,"SJAG_00958":null,"SJAG_00962":null,"SJAG_00963":null,"SJAG_00964":null,"SJAG_00965":null,"SJAG_00966":null,"SJAG_00968":null,"SJAG_00970":null,"SJAG_00971":null,"SJAG_00972":null,"SJAG_00973":null,"SJAG_00975":null,"SJAG_00978":null,"SJAG_00979":null,"SJAG_00980":null,"SJAG_00983":null,"SJAG_00984":null,"SJAG_00986":null,"SJAG_00987":null,"SJAG_00988":null,"SJAG_00989":null,"SJAG_00992":null,"SJAG_00996":null,"SJAG_00998":null,"SJAG_00999":null,"SJAG_01000":null,"SJAG_01002":null,"SJAG_01003":null,"SJAG_01004":null,"SJAG_01005":null,"SJAG_01006":null,"SJAG_01007":null,"SJAG_01008":null,"SJAG_01010":null,"SJAG_01012":null,"SJAG_01016":null,"SJAG_01017":null,"SJAG_01018":null,"SJAG_01019":null,"SJAG_01020":null,"SJAG_01021":null,"SJAG_01028":null,"SJAG_01036":null,"SJAG_01039":null,"SJAG_01040":null,"SJAG_01043":null,"SJAG_01044":null,"SJAG_01045":null,"SJAG_01047":null,"SJAG_01049":null,"SJAG_01050":null,"SJAG_01052":null,"SJAG_01055":null,"SJAG_01056":null,"SJAG_01057":null,"SJAG_01058":null,"SJAG_01059":null,"SJAG_01061":null,"SJAG_01062":null,"SJAG_01064":null,"SJAG_01065":null,"SJAG_01067":null,"SJAG_01069":null,"SJAG_01070":null,"SJAG_01073":null,"SJAG_01074":null,"SJAG_01075":null,"SJAG_01077":null,"SJAG_01080":null,"SJAG_01082":null,"SJAG_01083":null,"SJAG_01087":null,"SJAG_01088":null,"SJAG_01095":null,"SJAG_01110":null,"SJAG_01112":null,"SJAG_01116":null,"SJAG_01117":null,"SJAG_01119":null,"SJAG_01120":null,"SJAG_01121":null,"SJAG_01122":null,"SJAG_01126":null,"SJAG_01127":null,"SJAG_01129":null,"SJAG_01132":null,"SJAG_01134":null,"SJAG_01136":null,"SJAG_01137":null,"SJAG_01139":null,"SJAG_01142":null,"SJAG_01146":null,"SJAG_01147":null,"SJAG_01148":null,"SJAG_01149":null,"SJAG_01151":null,"SJAG_01152":null,"SJAG_01159":null,"SJAG_01160":null,"SJAG_01161":null,"SJAG_01162":null,"SJAG_01163":null,"SJAG_01164":null,"SJAG_01167":null,"SJAG_01168":null,"SJAG_01169":null,"SJAG_01171":null,"SJAG_01172":null,"SJAG_01173":null,"SJAG_01176":null,"SJAG_01178":null,"SJAG_01179":null,"SJAG_01180":null,"SJAG_01182":null,"SJAG_01183":null,"SJAG_01185":null,"SJAG_01186":null,"SJAG_01187":null,"SJAG_01189":null,"SJAG_01192":null,"SJAG_01193":null,"SJAG_01194":null,"SJAG_01197":null,"SJAG_01198":null,"SJAG_01199":null,"SJAG_01200":null,"SJAG_01202":null,"SJAG_01203":null,"SJAG_01204":null,"SJAG_01209":null,"SJAG_01211":null,"SJAG_01213":null,"SJAG_01214":null,"SJAG_01215":null,"SJAG_01221":null,"SJAG_01222":null,"SJAG_01226":null,"SJAG_01227":null,"SJAG_01229":null,"SJAG_01231":null,"SJAG_01234":null,"SJAG_01235":null,"SJAG_01236":null,"SJAG_01238":null,"SJAG_01239":null,"SJAG_01240":null,"SJAG_01242":null,"SJAG_01243":null,"SJAG_01245":null,"SJAG_01246":null,"SJAG_01248":null,"SJAG_01253":null,"SJAG_01259":null,"SJAG_01260":null,"SJAG_01261":null,"SJAG_01262":null,"SJAG_01263":null,"SJAG_01264":null,"SJAG_01266":null,"SJAG_01268":null,"SJAG_01269":null,"SJAG_01270":null,"SJAG_01271":null,"SJAG_01272":null,"SJAG_01274":null,"SJAG_01276":null,"SJAG_01277":null,"SJAG_01281":null,"SJAG_01286":null,"SJAG_01288":null,"SJAG_01290":null,"SJAG_01292":null,"SJAG_01293":null,"SJAG_01296":null,"SJAG_01298":null,"SJAG_01299":null,"SJAG_01300":null,"SJAG_01301":null,"SJAG_01302":null,"SJAG_01303":null,"SJAG_01305":null,"SJAG_01308":null,"SJAG_01309":null,"SJAG_01310":null,"SJAG_01313":null,"SJAG_01314":null,"SJAG_01315":null,"SJAG_01320":null,"SJAG_01321":null,"SJAG_01326":null,"SJAG_01327":null,"SJAG_01329":null,"SJAG_01330":null,"SJAG_01331":null,"SJAG_01336":null,"SJAG_01338":null,"SJAG_01339":null,"SJAG_01343":null,"SJAG_01346":null,"SJAG_01349":null,"SJAG_01351":null,"SJAG_01352":null,"SJAG_01353":null,"SJAG_01354":null,"SJAG_01355":null,"SJAG_01358":null,"SJAG_01359":null,"SJAG_01360":null,"SJAG_01364":null,"SJAG_01365":null,"SJAG_01366":null,"SJAG_01368":null,"SJAG_01372":null,"SJAG_01373":null,"SJAG_01374":null,"SJAG_01375":null,"SJAG_01376":null,"SJAG_01377":null,"SJAG_01383":null,"SJAG_01384":null,"SJAG_01385":null,"SJAG_01386":null,"SJAG_01387":null,"SJAG_01388":null,"SJAG_01389":null,"SJAG_01391":null,"SJAG_01397":null,"SJAG_01400":null,"SJAG_01401":null,"SJAG_01404":null,"SJAG_01405":null,"SJAG_01408":null,"SJAG_01409":null,"SJAG_01410":null,"SJAG_01411":null,"SJAG_01413":null,"SJAG_01414":null,"SJAG_01415":null,"SJAG_01416":null,"SJAG_01417":null,"SJAG_01422":null,"SJAG_01425":null,"SJAG_01427":null,"SJAG_01430":null,"SJAG_01432":null,"SJAG_01433":null,"SJAG_01435":null,"SJAG_01436":null,"SJAG_01438":null,"SJAG_01443":null,"SJAG_01444":null,"SJAG_01445":null,"SJAG_01449":null,"SJAG_01452":null,"SJAG_01454":null,"SJAG_01455":null,"SJAG_01456":null,"SJAG_01457":null,"SJAG_01458":null,"SJAG_01459":null,"SJAG_01461":null,"SJAG_01463":null,"SJAG_01465":null,"SJAG_01466":null,"SJAG_01467":null,"SJAG_01469":null,"SJAG_01470":null,"SJAG_01471":null,"SJAG_01472":null,"SJAG_01474":null,"SJAG_01476":null,"SJAG_01478":null,"SJAG_01480":null,"SJAG_01482":null,"SJAG_01487":null,"SJAG_01488":null,"SJAG_01491":null,"SJAG_01492":null,"SJAG_01494":null,"SJAG_01497":null,"SJAG_01498":null,"SJAG_01500":null,"SJAG_01501":null,"SJAG_01503":null,"SJAG_01504":null,"SJAG_01505":null,"SJAG_01508":null,"SJAG_01509":null,"SJAG_01510":null,"SJAG_01511":null,"SJAG_01516":null,"SJAG_01518":null,"SJAG_01519":null,"SJAG_01521":null,"SJAG_01522":null,"SJAG_01523":null,"SJAG_01524":null,"SJAG_01527":null,"SJAG_01528":null,"SJAG_01529":null,"SJAG_01531":null,"SJAG_01532":null,"SJAG_01533":null,"SJAG_01534":null,"SJAG_01541":null,"SJAG_01545":null,"SJAG_01547":null,"SJAG_01548":null,"SJAG_01551":null,"SJAG_01556":null,"SJAG_01557":null,"SJAG_01558":null,"SJAG_01560":null,"SJAG_01561":null,"SJAG_01562":null,"SJAG_01565":null,"SJAG_01566":null,"SJAG_01568":null,"SJAG_01570":null,"SJAG_01571":null,"SJAG_01575":null,"SJAG_01577":null,"SJAG_01580":null,"SJAG_01581":null,"SJAG_01582":null,"SJAG_01585":null,"SJAG_01586":null,"SJAG_01588":null,"SJAG_01589":null,"SJAG_01590":null,"SJAG_01591":null,"SJAG_01592":null,"SJAG_01593":null,"SJAG_01595":null,"SJAG_01596":null,"SJAG_01597":null,"SJAG_01600":null,"SJAG_01604":null,"SJAG_01606":null,"SJAG_01608":null,"SJAG_01609":null,"SJAG_01610":null,"SJAG_01612":null,"SJAG_01615":null,"SJAG_01616":null,"SJAG_01618":null,"SJAG_01620":null,"SJAG_01621":null,"SJAG_01622":null,"SJAG_01623":null,"SJAG_01624":null,"SJAG_01625":null,"SJAG_01630":null,"SJAG_01632":null,"SJAG_01633":null,"SJAG_01634":null,"SJAG_01636":null,"SJAG_01638":null,"SJAG_01639":null,"SJAG_01640":null,"SJAG_01641":null,"SJAG_01642":null,"SJAG_01643":null,"SJAG_01644":null,"SJAG_01646":null,"SJAG_01647":null,"SJAG_01648":null,"SJAG_01650":null,"SJAG_01653":null,"SJAG_01655":null,"SJAG_01659":null,"SJAG_01661":null,"SJAG_01662":null,"SJAG_01664":null,"SJAG_01665":null,"SJAG_01668":null,"SJAG_01669":null,"SJAG_01670":null,"SJAG_01671":null,"SJAG_01672":null,"SJAG_01673":null,"SJAG_01676":null,"SJAG_01680":null,"SJAG_01684":null,"SJAG_01685":null,"SJAG_01686":null,"SJAG_01690":null,"SJAG_01693":null,"SJAG_01694":null,"SJAG_01695":null,"SJAG_01696":null,"SJAG_01697":null,"SJAG_01698":null,"SJAG_01702":null,"SJAG_01704":null,"SJAG_01707":null,"SJAG_01710":null,"SJAG_01713":null,"SJAG_01714":null,"SJAG_01715":null,"SJAG_01717":null,"SJAG_01722":null,"SJAG_01724":null,"SJAG_01725":null,"SJAG_01731":null,"SJAG_01733":null,"SJAG_01741":null,"SJAG_01744":null,"SJAG_01747":null,"SJAG_01748":null,"SJAG_01753":null,"SJAG_01759":null,"SJAG_01760":null,"SJAG_01762":null,"SJAG_01764":null,"SJAG_01765":null,"SJAG_01766":null,"SJAG_01768":null,"SJAG_01769":null,"SJAG_01774":null,"SJAG_01776":null,"SJAG_01781":null,"SJAG_01783":null,"SJAG_01784":null,"SJAG_01786":null,"SJAG_01787":null,"SJAG_01789":null,"SJAG_01790":null,"SJAG_01798":null,"SJAG_01799":null,"SJAG_01805":null,"SJAG_01807":null,"SJAG_01808":null,"SJAG_01809":null,"SJAG_01811":null,"SJAG_01813":null,"SJAG_01814":null,"SJAG_01816":null,"SJAG_01817":null,"SJAG_01818":null,"SJAG_01819":null,"SJAG_01822":null,"SJAG_01824":null,"SJAG_01825":null,"SJAG_01826":null,"SJAG_01827":null,"SJAG_01829":null,"SJAG_01831":null,"SJAG_01835":null,"SJAG_01836":null,"SJAG_01838":null,"SJAG_01839":null,"SJAG_01841":null,"SJAG_01843":null,"SJAG_01850":null,"SJAG_01851":null,"SJAG_01858":null,"SJAG_01859":null,"SJAG_01860":null,"SJAG_01862":null,"SJAG_01863":null,"SJAG_01865":null,"SJAG_01866":null,"SJAG_01868":null,"SJAG_01870":null,"SJAG_01872":null,"SJAG_01874":null,"SJAG_01875":null,"SJAG_01876":null,"SJAG_01877":null,"SJAG_01878":null,"SJAG_01879":null,"SJAG_01880":null,"SJAG_01881":null,"SJAG_01882":null,"SJAG_01885":null,"SJAG_01887":null,"SJAG_01888":null,"SJAG_01890":null,"SJAG_01894":null,"SJAG_01895":null,"SJAG_01896":null,"SJAG_01897":null,"SJAG_01900":null,"SJAG_01901":null,"SJAG_01903":null,"SJAG_01906":null,"SJAG_01907":null,"SJAG_01909":null,"SJAG_01912":null,"SJAG_01913":null,"SJAG_01914":null,"SJAG_01918":null,"SJAG_01919":null,"SJAG_01922":null,"SJAG_01923":null,"SJAG_01924":null,"SJAG_01926":null,"SJAG_01927":null,"SJAG_01929":null,"SJAG_01930":null,"SJAG_01935":null,"SJAG_01936":null,"SJAG_01937":null,"SJAG_01938":null,"SJAG_01941":null,"SJAG_01942":null,"SJAG_01945":null,"SJAG_01946":null,"SJAG_01948":null,"SJAG_01950":null,"SJAG_01951":null,"SJAG_01953":null,"SJAG_01954":null,"SJAG_01955":null,"SJAG_01956":null,"SJAG_01957":null,"SJAG_01958":null,"SJAG_01964":null,"SJAG_01968":null,"SJAG_01971":null,"SJAG_01972":null,"SJAG_01973":null,"SJAG_01974":null,"SJAG_01983":null,"SJAG_01993":null,"SJAG_01994":null,"SJAG_01995":null,"SJAG_01996":null,"SJAG_01997":null,"SJAG_01998":null,"SJAG_02006":null,"SJAG_02007":null,"SJAG_02010":null,"SJAG_02015":null,"SJAG_02016":null,"SJAG_02017":null,"SJAG_02018":null,"SJAG_02019":null,"SJAG_02020":null,"SJAG_02021":null,"SJAG_02022":null,"SJAG_02024":null,"SJAG_02025":null,"SJAG_02026":null,"SJAG_02027":null,"SJAG_02029":null,"SJAG_02031":null,"SJAG_02033":null,"SJAG_02034":null,"SJAG_02036":null,"SJAG_02037":null,"SJAG_02038":null,"SJAG_02039":null,"SJAG_02040":null,"SJAG_02041":null,"SJAG_02043":null,"SJAG_02046":null,"SJAG_02056":null,"SJAG_02057":null,"SJAG_02058":null,"SJAG_02061":null,"SJAG_02063":null,"SJAG_02064":null,"SJAG_02065":null,"SJAG_02066":null,"SJAG_02067":null,"SJAG_02070":null,"SJAG_02071":null,"SJAG_02074":null,"SJAG_02075":null,"SJAG_02076":null,"SJAG_02077":null,"SJAG_02078":null,"SJAG_02079":null,"SJAG_02080":null,"SJAG_02081":null,"SJAG_02082":null,"SJAG_02083":null,"SJAG_02084":null,"SJAG_02085":null,"SJAG_02091":null,"SJAG_02093":null,"SJAG_02094":null,"SJAG_02098":null,"SJAG_02099":null,"SJAG_02100":null,"SJAG_02101":null,"SJAG_02102":null,"SJAG_02104":null,"SJAG_02106":null,"SJAG_02114":null,"SJAG_02117":null,"SJAG_02121":null,"SJAG_02125":null,"SJAG_02132":null,"SJAG_02147":null,"SJAG_02148":null,"SJAG_02150":null,"SJAG_02156":null,"SJAG_02158":null,"SJAG_02163":null,"SJAG_02164":null,"SJAG_02165":null,"SJAG_02168":null,"SJAG_02171":null,"SJAG_02172":null,"SJAG_02174":null,"SJAG_02176":null,"SJAG_02177":null,"SJAG_02180":null,"SJAG_02182":null,"SJAG_02184":null,"SJAG_02187":null,"SJAG_02192":null,"SJAG_02193":null,"SJAG_02194":null,"SJAG_02197":null,"SJAG_02199":null,"SJAG_02200":null,"SJAG_02201":null,"SJAG_02205":null,"SJAG_02206":null,"SJAG_02207":null,"SJAG_02208":null,"SJAG_02210":null,"SJAG_02212":null,"SJAG_02213":null,"SJAG_02214":null,"SJAG_02215":null,"SJAG_02222":null,"SJAG_02226":null,"SJAG_02227":null,"SJAG_02228":null,"SJAG_02231":null,"SJAG_02235":null,"SJAG_02236":null,"SJAG_02239":null,"SJAG_02240":null,"SJAG_02241":null,"SJAG_02242":null,"SJAG_02243":null,"SJAG_02244":null,"SJAG_02245":null,"SJAG_02247":null,"SJAG_02249":null,"SJAG_02250":null,"SJAG_02253":null,"SJAG_02255":null,"SJAG_02256":null,"SJAG_02260":null,"SJAG_02261":null,"SJAG_02263":null,"SJAG_02264":null,"SJAG_02267":null,"SJAG_02268":null,"SJAG_02271":null,"SJAG_02274":null,"SJAG_02275":null,"SJAG_02276":null,"SJAG_02279":null,"SJAG_02281":null,"SJAG_02282":null,"SJAG_02283":null,"SJAG_02285":null,"SJAG_02287":null,"SJAG_02288":null,"SJAG_02289":null,"SJAG_02292":null,"SJAG_02293":null,"SJAG_02294":null,"SJAG_02296":null,"SJAG_02297":null,"SJAG_02298":null,"SJAG_02300":null,"SJAG_02302":null,"SJAG_02303":null,"SJAG_02304":null,"SJAG_02305":null,"SJAG_02306":null,"SJAG_02308":null,"SJAG_02311":null,"SJAG_02312":null,"SJAG_02314":null,"SJAG_02315":null,"SJAG_02319":null,"SJAG_02321":null,"SJAG_02322":null,"SJAG_02323":null,"SJAG_02324":null,"SJAG_02328":null,"SJAG_02330":null,"SJAG_02331":null,"SJAG_02334":null,"SJAG_02335":null,"SJAG_02336":null,"SJAG_02338":null,"SJAG_02340":null,"SJAG_02341":null,"SJAG_02342":null,"SJAG_02344":null,"SJAG_02345":null,"SJAG_02348":null,"SJAG_02349":null,"SJAG_02354":null,"SJAG_02355":null,"SJAG_02356":null,"SJAG_02358":null,"SJAG_02360":null,"SJAG_02364":null,"SJAG_02366":null,"SJAG_02367":null,"SJAG_02368":null,"SJAG_02370":null,"SJAG_02371":null,"SJAG_02372":null,"SJAG_02374":null,"SJAG_02375":null,"SJAG_02376":null,"SJAG_02377":null,"SJAG_02378":null,"SJAG_02379":null,"SJAG_02380":null,"SJAG_02381":null,"SJAG_02382":null,"SJAG_02383":null,"SJAG_02384":null,"SJAG_02385":null,"SJAG_02386":null,"SJAG_02388":null,"SJAG_02389":null,"SJAG_02390":null,"SJAG_02392":null,"SJAG_02394":null,"SJAG_02395":null,"SJAG_02396":null,"SJAG_02397":null,"SJAG_02399":null,"SJAG_02404":null,"SJAG_02405":null,"SJAG_02406":null,"SJAG_02408":null,"SJAG_02413":null,"SJAG_02414":null,"SJAG_02415":null,"SJAG_02417":null,"SJAG_02418":null,"SJAG_02420":null,"SJAG_02421":null,"SJAG_02422":null,"SJAG_02424":null,"SJAG_02425":null,"SJAG_02426":null,"SJAG_02427":null,"SJAG_02428":null,"SJAG_02429":null,"SJAG_02430":null,"SJAG_02431":null,"SJAG_02432":null,"SJAG_02437":null,"SJAG_02441":null,"SJAG_02445":null,"SJAG_02446":null,"SJAG_02447":null,"SJAG_02450":null,"SJAG_02451":null,"SJAG_02455":null,"SJAG_02457":null,"SJAG_02458":null,"SJAG_02460":null,"SJAG_02461":null,"SJAG_02462":null,"SJAG_02464":null,"SJAG_02468":null,"SJAG_02469":null,"SJAG_02471":null,"SJAG_02472":null,"SJAG_02473":null,"SJAG_02474":null,"SJAG_02477":null,"SJAG_02479":null,"SJAG_02481":null,"SJAG_02484":null,"SJAG_02486":null,"SJAG_02488":null,"SJAG_02491":null,"SJAG_02492":null,"SJAG_02493":null,"SJAG_02494":null,"SJAG_02496":null,"SJAG_02497":null,"SJAG_02498":null,"SJAG_02501":null,"SJAG_02502":null,"SJAG_02503":null,"SJAG_02505":null,"SJAG_02506":null,"SJAG_02508":null,"SJAG_02509":null,"SJAG_02511":null,"SJAG_02515":null,"SJAG_02516":null,"SJAG_02519":null,"SJAG_02520":null,"SJAG_02521":null,"SJAG_02523":null,"SJAG_02525":null,"SJAG_02526":null,"SJAG_02527":null,"SJAG_02528":null,"SJAG_02530":null,"SJAG_02532":null,"SJAG_02534":null,"SJAG_02535":null,"SJAG_02536":null,"SJAG_02539":null,"SJAG_02540":null,"SJAG_02541":null,"SJAG_02542":null,"SJAG_02545":null,"SJAG_02546":null,"SJAG_02551":null,"SJAG_02554":null,"SJAG_02556":null,"SJAG_02558":null,"SJAG_02560":null,"SJAG_02561":null,"SJAG_02562":null,"SJAG_02563":null,"SJAG_02564":null,"SJAG_02565":null,"SJAG_02566":null,"SJAG_02570":null,"SJAG_02571":null,"SJAG_02573":null,"SJAG_02575":null,"SJAG_02578":null,"SJAG_02580":null,"SJAG_02581":null,"SJAG_02582":null,"SJAG_02583":null,"SJAG_02584":null,"SJAG_02588":null,"SJAG_02589":null,"SJAG_02590":null,"SJAG_02592":null,"SJAG_02593":null,"SJAG_02595":null,"SJAG_02596":null,"SJAG_02597":null,"SJAG_02598":null,"SJAG_02599":null,"SJAG_02600":null,"SJAG_02601":null,"SJAG_02602":null,"SJAG_02604":null,"SJAG_02605":null,"SJAG_02608":null,"SJAG_02610":null,"SJAG_02615":null,"SJAG_02618":null,"SJAG_02619":null,"SJAG_02620":null,"SJAG_02621":null,"SJAG_02625":null,"SJAG_02626":null,"SJAG_02627":null,"SJAG_02628":null,"SJAG_02629":null,"SJAG_02637":null,"SJAG_02643":null,"SJAG_02645":null,"SJAG_02647":null,"SJAG_02648":null,"SJAG_02649":null,"SJAG_02654":null,"SJAG_02655":null,"SJAG_02658":null,"SJAG_02659":null,"SJAG_02660":null,"SJAG_02661":null,"SJAG_02663":null,"SJAG_02666":null,"SJAG_02667":null,"SJAG_02668":null,"SJAG_02679":null,"SJAG_02680":null,"SJAG_02681":null,"SJAG_02684":null,"SJAG_02685":null,"SJAG_02686":null,"SJAG_02688":null,"SJAG_02689":null,"SJAG_02690":null,"SJAG_02691":null,"SJAG_02692":null,"SJAG_02696":null,"SJAG_02698":null,"SJAG_02700":null,"SJAG_02702":null,"SJAG_02703":null,"SJAG_02704":null,"SJAG_02705":null,"SJAG_02706":null,"SJAG_02707":null,"SJAG_02708":null,"SJAG_02713":null,"SJAG_02716":null,"SJAG_02717":null,"SJAG_02719":null,"SJAG_02721":null,"SJAG_02723":null,"SJAG_02724":null,"SJAG_02725":null,"SJAG_02727":null,"SJAG_02728":null,"SJAG_02729":null,"SJAG_02730":null,"SJAG_02734":null,"SJAG_02735":null,"SJAG_02736":null,"SJAG_02738":null,"SJAG_02741":null,"SJAG_02744":null,"SJAG_02746":null,"SJAG_02747":null,"SJAG_02748":null,"SJAG_02749":null,"SJAG_02750":null,"SJAG_02751":null,"SJAG_02752":null,"SJAG_02753":null,"SJAG_02754":null,"SJAG_02755":null,"SJAG_02756":null,"SJAG_02757":null,"SJAG_02759":null,"SJAG_02760":null,"SJAG_02762":null,"SJAG_02763":null,"SJAG_02765":null,"SJAG_02768":null,"SJAG_02769":null,"SJAG_02771":null,"SJAG_02772":null,"SJAG_02773":null,"SJAG_02774":null,"SJAG_02778":null,"SJAG_02785":null,"SJAG_02786":null,"SJAG_02790":null,"SJAG_02791":null,"SJAG_02794":null,"SJAG_02796":null,"SJAG_02797":null,"SJAG_02799":null,"SJAG_02800":null,"SJAG_02802":null,"SJAG_02803":null,"SJAG_02809":null,"SJAG_02810":null,"SJAG_02811":null,"SJAG_02814":null,"SJAG_02815":null,"SJAG_02817":null,"SJAG_02818":null,"SJAG_02819":null,"SJAG_02821":null,"SJAG_02822":null,"SJAG_02824":null,"SJAG_02825":null,"SJAG_02829":null,"SJAG_02830":null,"SJAG_02831":null,"SJAG_02833":null,"SJAG_02834":null,"SJAG_02835":null,"SJAG_02837":null,"SJAG_02838":null,"SJAG_02840":null,"SJAG_02841":null,"SJAG_02842":null,"SJAG_02843":null,"SJAG_02844":null,"SJAG_02847":null,"SJAG_02848":null,"SJAG_02849":null,"SJAG_02850":null,"SJAG_02851":null,"SJAG_02853":null,"SJAG_02854":null,"SJAG_02856":null,"SJAG_02858":null,"SJAG_02860":null,"SJAG_02866":null,"SJAG_02872":null,"SJAG_02873":null,"SJAG_02875":null,"SJAG_02878":null,"SJAG_02879":null,"SJAG_02883":null,"SJAG_02885":null,"SJAG_02887":null,"SJAG_02889":null,"SJAG_02890":null,"SJAG_02895":null,"SJAG_02896":null,"SJAG_02897":null,"SJAG_02898":null,"SJAG_02900":null,"SJAG_02903":null,"SJAG_02904":null,"SJAG_02908":null,"SJAG_02911":null,"SJAG_02912":null,"SJAG_02913":null,"SJAG_02914":null,"SJAG_02916":null,"SJAG_02920":null,"SJAG_02922":null,"SJAG_02926":null,"SJAG_02943":null,"SJAG_02946":null,"SJAG_02947":null,"SJAG_02948":null,"SJAG_02950":null,"SJAG_02951":null,"SJAG_02952":null,"SJAG_02954":null,"SJAG_02955":null,"SJAG_02957":null,"SJAG_02958":null,"SJAG_02959":null,"SJAG_02963":null,"SJAG_02974":null,"SJAG_02977":null,"SJAG_02978":null,"SJAG_02980":null,"SJAG_02984":null,"SJAG_02985":null,"SJAG_02988":null,"SJAG_02990":null,"SJAG_02991":null,"SJAG_02993":null,"SJAG_02994":null,"SJAG_02995":null,"SJAG_02996":null,"SJAG_02997":null,"SJAG_02998":null,"SJAG_03002":null,"SJAG_03006":null,"SJAG_03007":null,"SJAG_03008":null,"SJAG_03011":null,"SJAG_03012":null,"SJAG_03014":null,"SJAG_03015":null,"SJAG_03016":null,"SJAG_03018":null,"SJAG_03023":null,"SJAG_03024":null,"SJAG_03025":null,"SJAG_03026":null,"SJAG_03028":null,"SJAG_03029":null,"SJAG_03035":null,"SJAG_03038":null,"SJAG_03039":null,"SJAG_03041":null,"SJAG_03044":null,"SJAG_03045":null,"SJAG_03046":null,"SJAG_03050":null,"SJAG_03054":null,"SJAG_03056":null,"SJAG_03057":null,"SJAG_03061":null,"SJAG_03062":null,"SJAG_03064":null,"SJAG_03066":null,"SJAG_03067":null,"SJAG_03068":null,"SJAG_03069":null,"SJAG_03070":null,"SJAG_03071":null,"SJAG_03072":null,"SJAG_03073":null,"SJAG_03077":null,"SJAG_03082":null,"SJAG_03086":null,"SJAG_03088":null,"SJAG_03091":null,"SJAG_03094":null,"SJAG_03096":null,"SJAG_03097":null,"SJAG_03098":null,"SJAG_03100":null,"SJAG_03102":null,"SJAG_03106":null,"SJAG_03107":null,"SJAG_03112":null,"SJAG_03114":null,"SJAG_03115":null,"SJAG_03118":null,"SJAG_03120":null,"SJAG_03121":null,"SJAG_03124":null,"SJAG_03125":null,"SJAG_03127":null,"SJAG_03128":null,"SJAG_03130":null,"SJAG_03131":null,"SJAG_03132":null,"SJAG_03133":null,"SJAG_03135":null,"SJAG_03137":null,"SJAG_03140":null,"SJAG_03143":null,"SJAG_03144":null,"SJAG_03147":null,"SJAG_03152":null,"SJAG_03153":null,"SJAG_03156":null,"SJAG_03157":null,"SJAG_03158":null,"SJAG_03159":null,"SJAG_03160":null,"SJAG_03162":null,"SJAG_03163":null,"SJAG_03164":null,"SJAG_03166":null,"SJAG_03167":null,"SJAG_03170":null,"SJAG_03173":null,"SJAG_03176":null,"SJAG_03179":null,"SJAG_03181":null,"SJAG_03182":null,"SJAG_03188":null,"SJAG_03192":null,"SJAG_03193":null,"SJAG_03196":null,"SJAG_03198":null,"SJAG_03199":null,"SJAG_03200":null,"SJAG_03204":null,"SJAG_03209":null,"SJAG_03210":null,"SJAG_03214":null,"SJAG_03219":null,"SJAG_03220":null,"SJAG_03222":null,"SJAG_03223":null,"SJAG_03224":null,"SJAG_03228":null,"SJAG_03230":null,"SJAG_03232":null,"SJAG_03233":null,"SJAG_03235":null,"SJAG_03236":null,"SJAG_03237":null,"SJAG_03238":null,"SJAG_03241":null,"SJAG_03244":null,"SJAG_03245":null,"SJAG_03250":null,"SJAG_03252":null,"SJAG_03254":null,"SJAG_03255":null,"SJAG_03256":null,"SJAG_03261":null,"SJAG_03262":null,"SJAG_03263":null,"SJAG_03266":null,"SJAG_03268":null,"SJAG_03270":null,"SJAG_03272":null,"SJAG_03273":null,"SJAG_03275":null,"SJAG_03276":null,"SJAG_03277":null,"SJAG_03278":null,"SJAG_03280":null,"SJAG_03283":null,"SJAG_03284":null,"SJAG_03286":null,"SJAG_03291":null,"SJAG_03292":null,"SJAG_03293":null,"SJAG_03295":null,"SJAG_03297":null,"SJAG_03298":null,"SJAG_03299":null,"SJAG_03300":null,"SJAG_03301":null,"SJAG_03303":null,"SJAG_03305":null,"SJAG_03306":null,"SJAG_03310":null,"SJAG_03312":null,"SJAG_03313":null,"SJAG_03315":null,"SJAG_03316":null,"SJAG_03319":null,"SJAG_03320":null,"SJAG_03321":null,"SJAG_03324":null,"SJAG_03326":null,"SJAG_03327":null,"SJAG_03328":null,"SJAG_03330":null,"SJAG_03332":null,"SJAG_03333":null,"SJAG_03335":null,"SJAG_03336":null,"SJAG_03342":null,"SJAG_03345":null,"SJAG_03349":null,"SJAG_03350":null,"SJAG_03351":null,"SJAG_03352":null,"SJAG_03354":null,"SJAG_03355":null,"SJAG_03362":null,"SJAG_03364":null,"SJAG_03366":null,"SJAG_03367":null,"SJAG_03371":null,"SJAG_03373":null,"SJAG_03374":null,"SJAG_03375":null,"SJAG_03376":null,"SJAG_03379":null,"SJAG_03383":null,"SJAG_03384":null,"SJAG_03385":null,"SJAG_03386":null,"SJAG_03395":null,"SJAG_03396":null,"SJAG_03398":null,"SJAG_03401":null,"SJAG_03403":null,"SJAG_03408":null,"SJAG_03409":null,"SJAG_03413":null,"SJAG_03414":null,"SJAG_03416":null,"SJAG_03418":null,"SJAG_03421":null,"SJAG_03422":null,"SJAG_03424":null,"SJAG_03425":null,"SJAG_03427":null,"SJAG_03434":null,"SJAG_03436":null,"SJAG_03440":null,"SJAG_03442":null,"SJAG_03447":null,"SJAG_03451":null,"SJAG_03452":null,"SJAG_03453":null,"SJAG_03454":null,"SJAG_03455":null,"SJAG_03457":null,"SJAG_03459":null,"SJAG_03461":null,"SJAG_03466":null,"SJAG_03467":null,"SJAG_03469":null,"SJAG_03470":null,"SJAG_03471":null,"SJAG_03475":null,"SJAG_03476":null,"SJAG_03481":null,"SJAG_03483":null,"SJAG_03484":null,"SJAG_03485":null,"SJAG_03491":null,"SJAG_03492":null,"SJAG_03494":null,"SJAG_03495":null,"SJAG_03498":null,"SJAG_03499":null,"SJAG_03501":null,"SJAG_03503":null,"SJAG_03504":null,"SJAG_03506":null,"SJAG_03509":null,"SJAG_03511":null,"SJAG_03515":null,"SJAG_03516":null,"SJAG_03524":null,"SJAG_03529":null,"SJAG_03531":null,"SJAG_03534":null,"SJAG_03535":null,"SJAG_03536":null,"SJAG_03537":null,"SJAG_03538":null,"SJAG_03539":null,"SJAG_03545":null,"SJAG_03546":null,"SJAG_03548":null,"SJAG_03551":null,"SJAG_03553":null,"SJAG_03555":null,"SJAG_03556":null,"SJAG_03558":null,"SJAG_03560":null,"SJAG_03561":null,"SJAG_03562":null,"SJAG_03563":null,"SJAG_03570":null,"SJAG_03572":null,"SJAG_03573":null,"SJAG_03574":null,"SJAG_03578":null,"SJAG_03579":null,"SJAG_03580":null,"SJAG_03581":null,"SJAG_03583":null,"SJAG_03584":null,"SJAG_03585":null,"SJAG_03586":null,"SJAG_03587":null,"SJAG_03588":null,"SJAG_03591":null,"SJAG_03592":null,"SJAG_03594":null,"SJAG_03595":null,"SJAG_03597":null,"SJAG_03598":null,"SJAG_03601":null,"SJAG_03602":null,"SJAG_03604":null,"SJAG_03606":null,"SJAG_03609":null,"SJAG_03614":null,"SJAG_03616":null,"SJAG_03617":null,"SJAG_03618":null,"SJAG_03621":null,"SJAG_03622":null,"SJAG_03623":null,"SJAG_03625":null,"SJAG_03626":null,"SJAG_03627":null,"SJAG_03628":null,"SJAG_03629":null,"SJAG_03631":null,"SJAG_03632":null,"SJAG_03633":null,"SJAG_03634":null,"SJAG_03635":null,"SJAG_03636":null,"SJAG_03638":null,"SJAG_03641":null,"SJAG_03643":null,"SJAG_03644":null,"SJAG_03646":null,"SJAG_03648":null,"SJAG_03649":null,"SJAG_03650":null,"SJAG_03651":null,"SJAG_03653":null,"SJAG_03654":null,"SJAG_03656":null,"SJAG_03658":null,"SJAG_03659":null,"SJAG_03662":null,"SJAG_03665":null,"SJAG_03666":null,"SJAG_03667":null,"SJAG_03669":null,"SJAG_03670":null,"SJAG_03671":null,"SJAG_03676":null,"SJAG_03679":null,"SJAG_03680":null,"SJAG_03682":null,"SJAG_03683":null,"SJAG_03684":null,"SJAG_03688":null,"SJAG_03692":null,"SJAG_03693":null,"SJAG_03694":null,"SJAG_03695":null,"SJAG_03696":null,"SJAG_03697":null,"SJAG_03698":null,"SJAG_03699":null,"SJAG_03701":null,"SJAG_03702":null,"SJAG_03703":null,"SJAG_03706":null,"SJAG_03708":null,"SJAG_03709":null,"SJAG_03712":null,"SJAG_03713":null,"SJAG_03715":null,"SJAG_03718":null,"SJAG_03720":null,"SJAG_03721":null,"SJAG_03723":null,"SJAG_03724":null,"SJAG_03730":null,"SJAG_03732":null,"SJAG_03739":null,"SJAG_03743":null,"SJAG_03744":null,"SJAG_03745":null,"SJAG_03755":null,"SJAG_03756":null,"SJAG_03759":null,"SJAG_03760":null,"SJAG_03773":null,"SJAG_03774":null,"SJAG_03775":null,"SJAG_03776":null,"SJAG_03777":null,"SJAG_03783":null,"SJAG_03784":null,"SJAG_03785":null,"SJAG_03786":null,"SJAG_03789":null,"SJAG_03790":null,"SJAG_03793":null,"SJAG_03794":null,"SJAG_03798":null,"SJAG_03799":null,"SJAG_03804":null,"SJAG_03805":null,"SJAG_03809":null,"SJAG_03810":null,"SJAG_03811":null,"SJAG_03813":null,"SJAG_03818":null,"SJAG_03820":null,"SJAG_03821":null,"SJAG_03827":null,"SJAG_03829":null,"SJAG_03836":null,"SJAG_03840":null,"SJAG_03842":null,"SJAG_03846":null,"SJAG_03849":null,"SJAG_03850":null,"SJAG_03851":null,"SJAG_03852":null,"SJAG_03854":null,"SJAG_03857":null,"SJAG_03858":null,"SJAG_03860":null,"SJAG_03861":null,"SJAG_03863":null,"SJAG_03864":null,"SJAG_03866":null,"SJAG_03869":null,"SJAG_03871":null,"SJAG_03872":null,"SJAG_03873":null,"SJAG_03876":null,"SJAG_03877":null,"SJAG_03878":null,"SJAG_03881":null,"SJAG_03882":null,"SJAG_03884":null,"SJAG_03886":null,"SJAG_03887":null,"SJAG_03888":null,"SJAG_03889":null,"SJAG_03891":null,"SJAG_03892":null,"SJAG_03895":null,"SJAG_03896":null,"SJAG_03897":null,"SJAG_03898":null,"SJAG_03899":null,"SJAG_03900":null,"SJAG_03901":null,"SJAG_03905":null,"SJAG_03906":null,"SJAG_03907":null,"SJAG_03909":null,"SJAG_03910":null,"SJAG_03913":null,"SJAG_03914":null,"SJAG_03915":null,"SJAG_03919":null,"SJAG_03920":null,"SJAG_03921":null,"SJAG_03922":null,"SJAG_03923":null,"SJAG_03924":null,"SJAG_03927":null,"SJAG_03929":null,"SJAG_03930":null,"SJAG_03931":null,"SJAG_03932":null,"SJAG_03933":null,"SJAG_03934":null,"SJAG_03935":null,"SJAG_03936":null,"SJAG_03943":null,"SJAG_03944":null,"SJAG_03946":null,"SJAG_03949":null,"SJAG_03950":null,"SJAG_03951":null,"SJAG_03952":null,"SJAG_03953":null,"SJAG_03954":null,"SJAG_03955":null,"SJAG_03956":null,"SJAG_03959":null,"SJAG_03960":null,"SJAG_03963":null,"SJAG_03964":null,"SJAG_03967":null,"SJAG_03968":null,"SJAG_03970":null,"SJAG_03972":null,"SJAG_03977":null,"SJAG_03982":null,"SJAG_03984":null,"SJAG_03985":null,"SJAG_03986":null,"SJAG_03987":null,"SJAG_03990":null,"SJAG_03992":null,"SJAG_03993":null,"SJAG_03994":null,"SJAG_03995":null,"SJAG_03996":null,"SJAG_04000":null,"SJAG_04001":null,"SJAG_04002":null,"SJAG_04003":null,"SJAG_04004":null,"SJAG_04006":null,"SJAG_04008":null,"SJAG_04011":null,"SJAG_04012":null,"SJAG_04014":null,"SJAG_04016":null,"SJAG_04017":null,"SJAG_04018":null,"SJAG_04020":null,"SJAG_04021":null,"SJAG_04023":null,"SJAG_04024":null,"SJAG_04025":null,"SJAG_04027":null,"SJAG_04028":null,"SJAG_04029":null,"SJAG_04030":null,"SJAG_04033":null,"SJAG_04036":null,"SJAG_04038":null,"SJAG_04039":null,"SJAG_04042":null,"SJAG_04044":null,"SJAG_04046":null,"SJAG_04047":null,"SJAG_04049":null,"SJAG_04052":null,"SJAG_04053":null,"SJAG_04054":null,"SJAG_04055":null,"SJAG_04056":null,"SJAG_04058":null,"SJAG_04059":null,"SJAG_04060":null,"SJAG_04065":null,"SJAG_04066":null,"SJAG_04068":null,"SJAG_04069":null,"SJAG_04070":null,"SJAG_04074":null,"SJAG_04076":null,"SJAG_04081":null,"SJAG_04084":null,"SJAG_04085":null,"SJAG_04087":null,"SJAG_04088":null,"SJAG_04089":null,"SJAG_04091":null,"SJAG_04092":null,"SJAG_04094":null,"SJAG_04095":null,"SJAG_04096":null,"SJAG_04097":null,"SJAG_04098":null,"SJAG_04100":null,"SJAG_04105":null,"SJAG_04107":null,"SJAG_04108":null,"SJAG_04109":null,"SJAG_04110":null,"SJAG_04111":null,"SJAG_04112":null,"SJAG_04113":null,"SJAG_04114":null,"SJAG_04117":null,"SJAG_04118":null,"SJAG_04119":null,"SJAG_04121":null,"SJAG_04123":null,"SJAG_04125":null,"SJAG_04126":null,"SJAG_04127":null,"SJAG_04130":null,"SJAG_04131":null,"SJAG_04136":null,"SJAG_04140":null,"SJAG_04142":null,"SJAG_04144":null,"SJAG_04145":null,"SJAG_04147":null,"SJAG_04149":null,"SJAG_04150":null,"SJAG_04153":null,"SJAG_04154":null,"SJAG_04155":null,"SJAG_04156":null,"SJAG_04159":null,"SJAG_04160":null,"SJAG_04162":null,"SJAG_04163":null,"SJAG_04165":null,"SJAG_04167":null,"SJAG_04171":null,"SJAG_04173":null,"SJAG_04174":null,"SJAG_04175":null,"SJAG_04176":null,"SJAG_04178":null,"SJAG_04179":null,"SJAG_04182":null,"SJAG_04183":null,"SJAG_04184":null,"SJAG_04185":null,"SJAG_04186":null,"SJAG_04187":null,"SJAG_04190":null,"SJAG_04192":null,"SJAG_04196":null,"SJAG_04198":null,"SJAG_04203":null,"SJAG_04205":null,"SJAG_04206":null,"SJAG_04210":null,"SJAG_04211":null,"SJAG_04213":null,"SJAG_04214":null,"SJAG_04216":null,"SJAG_04217":null,"SJAG_04218":null,"SJAG_04221":null,"SJAG_04222":null,"SJAG_04224":null,"SJAG_04228":null,"SJAG_04230":null,"SJAG_04231":null,"SJAG_04232":null,"SJAG_04233":null,"SJAG_04235":null,"SJAG_04236":null,"SJAG_04237":null,"SJAG_04248":null,"SJAG_04249":null,"SJAG_04252":null,"SJAG_04258":null,"SJAG_04261":null,"SJAG_04262":null,"SJAG_04263":null,"SJAG_04265":null,"SJAG_04270":null,"SJAG_04271":null,"SJAG_04275":null,"SJAG_04276":null,"SJAG_04280":null,"SJAG_04282":null,"SJAG_04283":null,"SJAG_04285":null,"SJAG_04287":null,"SJAG_04288":null,"SJAG_04289":null,"SJAG_04292":null,"SJAG_04293":null,"SJAG_04294":null,"SJAG_04295":null,"SJAG_04296":null,"SJAG_04299":null,"SJAG_04300":null,"SJAG_04301":null,"SJAG_04304":null,"SJAG_04305":null,"SJAG_04306":null,"SJAG_04307":null,"SJAG_04308":null,"SJAG_04311":null,"SJAG_04312":null,"SJAG_04316":null,"SJAG_04318":null,"SJAG_04320":null,"SJAG_04321":null,"SJAG_04323":null,"SJAG_04324":null,"SJAG_04327":null,"SJAG_04328":null,"SJAG_04330":null,"SJAG_04332":null,"SJAG_04334":null,"SJAG_04335":null,"SJAG_04336":null,"SJAG_04337":null,"SJAG_04338":null,"SJAG_04341":null,"SJAG_04342":null,"SJAG_04343":null,"SJAG_04345":null,"SJAG_04346":null,"SJAG_04349":null,"SJAG_04351":null,"SJAG_04352":null,"SJAG_04357":null,"SJAG_04358":null,"SJAG_04359":null,"SJAG_04362":null,"SJAG_04363":null,"SJAG_04366":null,"SJAG_04367":null,"SJAG_04368":null,"SJAG_04370":null,"SJAG_04372":null,"SJAG_04375":null,"SJAG_04376":null,"SJAG_04378":null,"SJAG_04379":null,"SJAG_04380":null,"SJAG_04384":null,"SJAG_04387":null,"SJAG_04388":null,"SJAG_04391":null,"SJAG_04395":null,"SJAG_04396":null,"SJAG_04397":null,"SJAG_04398":null,"SJAG_04399":null,"SJAG_04400":null,"SJAG_04401":null,"SJAG_04402":null,"SJAG_04404":null,"SJAG_04405":null,"SJAG_04407":null,"SJAG_04408":null,"SJAG_04409":null,"SJAG_04411":null,"SJAG_04414":null,"SJAG_04424":null,"SJAG_04425":null,"SJAG_04426":null,"SJAG_04427":null,"SJAG_04432":null,"SJAG_04433":null,"SJAG_04434":null,"SJAG_04435":null,"SJAG_04449":null,"SJAG_04451":null,"SJAG_04457":null,"SJAG_04459":null,"SJAG_04460":null,"SJAG_04461":null,"SJAG_04462":null,"SJAG_04465":null,"SJAG_04468":null,"SJAG_04469":null,"SJAG_04470":null,"SJAG_04472":null,"SJAG_04473":null,"SJAG_04474":null,"SJAG_04475":null,"SJAG_04476":null,"SJAG_04479":null,"SJAG_04480":null,"SJAG_04481":null,"SJAG_04483":null,"SJAG_04484":null,"SJAG_04486":null,"SJAG_04487":null,"SJAG_04488":null,"SJAG_04489":null,"SJAG_04492":null,"SJAG_04494":null,"SJAG_04495":null,"SJAG_04496":null,"SJAG_04497":null,"SJAG_04498":null,"SJAG_04499":null,"SJAG_04500":null,"SJAG_04501":null,"SJAG_04502":null,"SJAG_04506":null,"SJAG_04507":null,"SJAG_04509":null,"SJAG_04511":null,"SJAG_04514":null,"SJAG_04516":null,"SJAG_04518":null,"SJAG_04519":null,"SJAG_04524":null,"SJAG_04527":null,"SJAG_04529":null,"SJAG_04530":null,"SJAG_04531":null,"SJAG_04532":null,"SJAG_04533":null,"SJAG_04534":null,"SJAG_04537":null,"SJAG_04539":null,"SJAG_04544":null,"SJAG_04545":null,"SJAG_04547":null,"SJAG_04549":null,"SJAG_04551":null,"SJAG_04552":null,"SJAG_04553":null,"SJAG_04562":null,"SJAG_04563":null,"SJAG_04569":null,"SJAG_04571":null,"SJAG_04572":null,"SJAG_04573":null,"SJAG_04577":null,"SJAG_04579":null,"SJAG_04580":null,"SJAG_04582":null,"SJAG_04587":null,"SJAG_04589":null,"SJAG_04591":null,"SJAG_04592":null,"SJAG_04597":null,"SJAG_04598":null,"SJAG_04599":null,"SJAG_04600":null,"SJAG_04601":null,"SJAG_04603":null,"SJAG_04609":null,"SJAG_04611":null,"SJAG_04612":null,"SJAG_04613":null,"SJAG_04616":null,"SJAG_04621":null,"SJAG_04622":null,"SJAG_04624":null,"SJAG_04626":null,"SJAG_04627":null,"SJAG_04628":null,"SJAG_04629":null,"SJAG_04631":null,"SJAG_04632":null,"SJAG_04634":null,"SJAG_04638":null,"SJAG_04640":null,"SJAG_04641":null,"SJAG_04643":null,"SJAG_04644":null,"SJAG_04645":null,"SJAG_04647":null,"SJAG_04650":null,"SJAG_04653":null,"SJAG_04654":null,"SJAG_04655":null,"SJAG_04656":null,"SJAG_04657":null,"SJAG_04661":null,"SJAG_04665":null,"SJAG_04666":null,"SJAG_04668":null,"SJAG_04669":null,"SJAG_04672":null,"SJAG_04674":null,"SJAG_04675":null,"SJAG_04678":null,"SJAG_04680":null,"SJAG_04681":null,"SJAG_04686":null,"SJAG_04688":null,"SJAG_04689":null,"SJAG_04695":null,"SJAG_04697":null,"SJAG_04698":null,"SJAG_04699":null,"SJAG_04700":null,"SJAG_04701":null,"SJAG_04705":null,"SJAG_04712":null,"SJAG_04715":null,"SJAG_04716":null,"SJAG_04717":null,"SJAG_04719":null,"SJAG_04724":null,"SJAG_04725":null,"SJAG_04728":null,"SJAG_04731":null,"SJAG_04732":null,"SJAG_04734":null,"SJAG_04735":null,"SJAG_04738":null,"SJAG_04743":null,"SJAG_04744":null,"SJAG_04745":null,"SJAG_04747":null,"SJAG_04749":null,"SJAG_04752":null,"SJAG_04753":null,"SJAG_04754":null,"SJAG_04755":null,"SJAG_04756":null,"SJAG_04757":null,"SJAG_04761":null,"SJAG_04762":null,"SJAG_04766":null,"SJAG_04767":null,"SJAG_04772":null,"SJAG_04777":null,"SJAG_04781":null,"SJAG_04783":null,"SJAG_04785":null,"SJAG_04791":null,"SJAG_04792":null,"SJAG_04810":null,"SJAG_04813":null,"SJAG_04814":null,"SJAG_04816":null,"SJAG_04818":null,"SJAG_04819":null,"SJAG_04821":null,"SJAG_04823":null,"SJAG_04824":null,"SJAG_04825":null,"SJAG_04827":null,"SJAG_04828":null,"SJAG_04829":null,"SJAG_04837":null,"SJAG_04838":null,"SJAG_04839":null,"SJAG_04840":null,"SJAG_04841":null,"SJAG_04842":null,"SJAG_04843":null,"SJAG_04845":null,"SJAG_04846":null,"SJAG_04847":null,"SJAG_04849":null,"SJAG_04850":null,"SJAG_04851":null,"SJAG_04852":null,"SJAG_04853":null,"SJAG_04859":null,"SJAG_04862":null,"SJAG_04863":null,"SJAG_04864":null,"SJAG_04865":null,"SJAG_04866":null,"SJAG_04867":null,"SJAG_04868":null,"SJAG_04870":null,"SJAG_04874":null,"SJAG_04877":null,"SJAG_04879":null,"SJAG_04880":null,"SJAG_04881":null,"SJAG_04882":null,"SJAG_04884":null,"SJAG_04886":null,"SJAG_04889":null,"SJAG_04890":null,"SJAG_04892":null,"SJAG_04894":null,"SJAG_04897":null,"SJAG_04898":null,"SJAG_04899":null,"SJAG_04901":null,"SJAG_04902":null,"SJAG_04903":null,"SJAG_04905":null,"SJAG_04906":null,"SJAG_04907":null,"SJAG_04908":null,"SJAG_04909":null,"SJAG_04911":null,"SJAG_04912":null,"SJAG_04913":null,"SJAG_04914":null,"SJAG_04916":null,"SJAG_04917":null,"SJAG_04920":null,"SJAG_04923":null,"SJAG_04924":null,"SJAG_04928":null,"SJAG_04931":null,"SJAG_04933":null,"SJAG_04934":null,"SJAG_04936":null,"SJAG_04938":null,"SJAG_04940":null,"SJAG_04944":null,"SJAG_04952":null,"SJAG_04955":null,"SJAG_04963":null,"SJAG_04965":null,"SJAG_04971":null,"SJAG_04972":null,"SJAG_04973":null,"SJAG_04974":null,"SJAG_04975":null,"SJAG_04978":null,"SJAG_04979":null,"SJAG_04980":null,"SJAG_04981":null,"SJAG_04982":null,"SJAG_04983":null,"SJAG_04986":null,"SJAG_04988":null,"SJAG_04994":null,"SJAG_04995":null,"SJAG_04996":null,"SJAG_04998":null,"SJAG_04999":null,"SJAG_05001":null,"SJAG_05003":null,"SJAG_05007":null,"SJAG_05008":null,"SJAG_05009":null,"SJAG_05010":null,"SJAG_05011":null,"SJAG_05014":null,"SJAG_05016":null,"SJAG_05017":null,"SJAG_05018":null,"SJAG_05019":null,"SJAG_05024":null,"SJAG_05033":null,"SJAG_05105":null,"SJAG_05173":null,"SJAG_05175":null,"SJAG_05184":null,"SJAG_05186":null,"SJAG_05187":null,"SJAG_05189":null,"SJAG_05190":null,"SJAG_05194":null,"SJAG_05200":null,"SJAG_05204":null,"SJAG_05208":null,"SJAG_05212":null,"SJAG_05213":null,"SJAG_05214":null,"SJAG_05218":null,"SJAG_05220":null,"SJAG_05228":null,"SJAG_05229":null,"SJAG_05230":null,"SJAG_05231":null,"SJAG_05235":null,"SJAG_05236":null,"SJAG_05237":null,"SJAG_05240":null,"SJAG_05247":null,"SJAG_05248":null,"SJAG_05252":null,"SJAG_05253":null,"SJAG_05257":null,"SJAG_05264":null,"SJAG_05271":null,"SJAG_05272":null,"SJAG_05273":null,"SJAG_05276":null,"SJAG_05277":null,"SJAG_05278":null,"SJAG_05280":null,"SJAG_05283":null,"SJAG_05287":null,"SJAG_05288":null,"SJAG_05290":null,"SJAG_05295":null,"SJAG_05296":null,"SJAG_05297":null,"SJAG_05300":null,"SJAG_05302":null,"SJAG_05304":null,"SJAG_05311":null,"SJAG_05313":null,"SJAG_05314":null,"SJAG_05316":null,"SJAG_05319":null,"SJAG_05322":null,"SJAG_05325":null,"SJAG_05327":null,"SJAG_05328":null,"SJAG_05342":null,"SJAG_05343":null,"SJAG_05344":null,"SJAG_05345":null,"SJAG_05346":null,"SJAG_05351":null,"SJAG_05353":null,"SJAG_05372":null,"SJAG_05373":null,"SJAG_05736":null,"SJAG_05977":null,"SJAG_05978":null,"SJAG_05979":null,"SJAG_06022":null,"SJAG_06284":null,"SJAG_06309":null,"SJAG_06588":null,"SJAG_06603":null,"SJAG_06611":null,"SJAG_06612":null,"SJAG_06621":null,"SJAG_06622":null,"SJAG_06634":null,"SJAG_06635":null,"SJAG_16453":null,"SJAG_16454":null,"SJAG_16455":null,"SJAG_16457":null,"SJAG_16459":null},"genotypes_by_uniquename":{},"ltp_gene_count":0,"ortholog_annotations":[],"paralog_annotations":[],"physical_interactions":[],"publication_year":"2011","pubmed_entrez_date":"2011-08-30","pubmed_publication_date":"Sep 2011","terms_by_termid":{"GO:0000002":null,"GO:0000009":null,"GO:0000014":null,"GO:0000026":null,"GO:0000028":null,"GO:0000030":null,"GO:0000032":null,"GO:0000033":null,"GO:0000035":null,"GO:0000036":null,"GO:0000045":null,"GO:0000049":null,"GO:0000050":null,"GO:0000053":null,"GO:0000054":null,"GO:0000055":null,"GO:0000056":null,"GO:0000064":null,"GO:0000070":null,"GO:0000073":null,"GO:0000082":null,"GO:0000095":null,"GO:0000103":null,"GO:0000105":null,"GO:0000107":null,"GO:0000110":null,"GO:0000111":null,"GO:0000122":null,"GO:0000124":null,"GO:0000126":null,"GO:0000127":null,"GO:0000136":null,"GO:0000137":null,"GO:0000138":null,"GO:0000139":null,"GO:0000140":null,"GO:0000145":null,"GO:0000146":null,"GO:0000147":null,"GO:0000149":null,"GO:0000150":null,"GO:0000151":null,"GO:0000155":null,"GO:0000159":null,"GO:0000162":null,"GO:0000170":null,"GO:0000171":null,"GO:0000172":null,"GO:0000175":null,"GO:0000176":null,"GO:0000177":null,"GO:0000182":null,"GO:0000213":null,"GO:0000214":null,"GO:0000215":null,"GO:0000221":null,"GO:0000225":null,"GO:0000226":null,"GO:0000228":null,"GO:0000243":null,"GO:0000244":null,"GO:0000245":null,"GO:0000246":null,"GO:0000248":null,"GO:0000250":null,"GO:0000253":null,"GO:0000254":null,"GO:0000256":null,"GO:0000274":null,"GO:0000276":null,"GO:0000278":null,"GO:0000280":null,"GO:0000281":null,"GO:0000285":null,"GO:0000287":null,"GO:0000288":null,"GO:0000289":null,"GO:0000290":null,"GO:0000291":null,"GO:0000294":null,"GO:0000297":null,"GO:0000298":null,"GO:0000307":null,"GO:0000309":null,"GO:0000324":null,"GO:0000328":null,"GO:0000329":null,"GO:0000333":null,"GO:0000338":null,"GO:0000339":null,"GO:0000340":null,"GO:0000349":null,"GO:0000350":null,"GO:0000379":null,"GO:0000387":null,"GO:0000389":null,"GO:0000390":null,"GO:0000395":null,"GO:0000400":null,"GO:0000402":null,"GO:0000403":null,"GO:0000407":null,"GO:0000408":null,"GO:0000417":null,"GO:0000423":null,"GO:0000439":null,"GO:0000445":null,"GO:0000447":null,"GO:0000448":null,"GO:0000454":null,"GO:0000455":null,"GO:0000460":null,"GO:0000461":null,"GO:0000462":null,"GO:0000463":null,"GO:0000466":null,"GO:0000467":null,"GO:0000470":null,"GO:0000472":null,"GO:0000479":null,"GO:0000480":null,"GO:0000481":null,"GO:0000492":null,"GO:0000493":null,"GO:0000494":null,"GO:0000495":null,"GO:0000500":null,"GO:0000506":null,"GO:0000701":null,"GO:0000706":null,"GO:0000707":null,"GO:0000712":null,"GO:0000723":null,"GO:0000724":null,"GO:0000725":null,"GO:0000727":null,"GO:0000730":null,"GO:0000742":null,"GO:0000774":null,"GO:0000776":null,"GO:0000785":null,"GO:0000793":null,"GO:0000794":null,"GO:0000811":null,"GO:0000812":null,"GO:0000813":null,"GO:0000814":null,"GO:0000815":null,"GO:0000822":null,"GO:0000824":null,"GO:0000828":null,"GO:0000829":null,"GO:0000906":null,"GO:0000932":null,"GO:0000935":null,"GO:0000938":null,"GO:0000949":null,"GO:0000956":null,"GO:0000964":null,"GO:0000965":null,"GO:0000972":null,"GO:0000973":null,"GO:0000974":null,"GO:0000976":null,"GO:0000977":null,"GO:0000978":null,"GO:0000981":null,"GO:0000993":null,"GO:0000994":null,"GO:0000995":null,"GO:0001002":null,"GO:0001003":null,"GO:0001006":null,"GO:0001018":null,"GO:0001042":null,"GO:0001046":null,"GO:0001054":null,"GO:0001055":null,"GO:0001056":null,"GO:0001097":null,"GO:0001113":null,"GO:0001139":null,"GO:0001147":null,"GO:0001156":null,"GO:0001163":null,"GO:0001164":null,"GO:0001165":null,"GO:0001179":null,"GO:0001181":null,"GO:0001188":null,"GO:0001193":null,"GO:0001228":null,"GO:0001401":null,"GO:0001405":null,"GO:0001409":null,"GO:0001561":null,"GO:0001671":null,"GO:0001676":null,"GO:0001678":null,"GO:0001680":null,"GO:0001682":null,"GO:0001731":null,"GO:0001732":null,"GO:0001965":null,"GO:0002055":null,"GO:0002094":null,"GO:0002143":null,"GO:0002144":null,"GO:0002181":null,"GO:0002183":null,"GO:0002184":null,"GO:0002188":null,"GO:0002189":null,"GO:0002926":null,"GO:0002939":null,"GO:0002940":null,"GO:0002943":null,"GO:0002953":null,"GO:0003333":null,"GO:0003400":null,"GO:0003677":null,"GO:0003678":null,"GO:0003682":null,"GO:0003684":null,"GO:0003689":null,"GO:0003690":null,"GO:0003691":null,"GO:0003697":null,"GO:0003700":null,"GO:0003711":null,"GO:0003712":null,"GO:0003713":null,"GO:0003714":null,"GO:0003721":null,"GO:0003723":null,"GO:0003724":null,"GO:0003727":null,"GO:0003729":null,"GO:0003730":null,"GO:0003735":null,"GO:0003743":null,"GO:0003746":null,"GO:0003747":null,"GO:0003755":null,"GO:0003756":null,"GO:0003785":null,"GO:0003786":null,"GO:0003825":null,"GO:0003838":null,"GO:0003839":null,"GO:0003841":null,"GO:0003842":null,"GO:0003843":null,"GO:0003847":null,"GO:0003849":null,"GO:0003852":null,"GO:0003860":null,"GO:0003862":null,"GO:0003864":null,"GO:0003866":null,"GO:0003872":null,"GO:0003873":null,"GO:0003876":null,"GO:0003879":null,"GO:0003881":null,"GO:0003883":null,"GO:0003884":null,"GO:0003885":null,"GO:0003887":null,"GO:0003899":null,"GO:0003906":null,"GO:0003910":null,"GO:0003919":null,"GO:0003921":null,"GO:0003924":null,"GO:0003934":null,"GO:0003937":null,"GO:0003938":null,"GO:0003939":null,"GO:0003941":null,"GO:0003942":null,"GO:0003949":null,"GO:0003951":null,"GO:0003952":null,"GO:0003958":null,"GO:0003960":null,"GO:0003962":null,"GO:0003972":null,"GO:0003977":null,"GO:0003978":null,"GO:0003980":null,"GO:0003984":null,"GO:0003985":null,"GO:0003987":null,"GO:0003989":null,"GO:0003993":null,"GO:0003994":null,"GO:0003999":null,"GO:0004001":null,"GO:0004013":null,"GO:0004014":null,"GO:0004015":null,"GO:0004017":null,"GO:0004018":null,"GO:0004019":null,"GO:0004020":null,"GO:0004021":null,"GO:0004022":null,"GO:0004024":null,"GO:0004029":null,"GO:0004032":null,"GO:0004033":null,"GO:0004035":null,"GO:0004037":null,"GO:0004042":null,"GO:0004044":null,"GO:0004045":null,"GO:0004053":null,"GO:0004055":null,"GO:0004056":null,"GO:0004057":null,"GO:0004059":null,"GO:0004066":null,"GO:0004067":null,"GO:0004069":null,"GO:0004070":null,"GO:0004072":null,"GO:0004073":null,"GO:0004076":null,"GO:0004077":null,"GO:0004088":null,"GO:0004089":null,"GO:0004096":null,"GO:0004100":null,"GO:0004103":null,"GO:0004105":null,"GO:0004106":null,"GO:0004107":null,"GO:0004108":null,"GO:0004109":null,"GO:0004115":null,"GO:0004124":null,"GO:0004126":null,"GO:0004127":null,"GO:0004128":null,"GO:0004140":null,"GO:0004141":null,"GO:0004144":null,"GO:0004146":null,"GO:0004149":null,"GO:0004151":null,"GO:0004156":null,"GO:0004160":null,"GO:0004161":null,"GO:0004163":null,"GO:0004168":null,"GO:0004169":null,"GO:0004170":null,"GO:0004176":null,"GO:0004180":null,"GO:0004185":null,"GO:0004190":null,"GO:0004197":null,"GO:0004222":null,"GO:0004252":null,"GO:0004298":null,"GO:0004305":null,"GO:0004306":null,"GO:0004309":null,"GO:0004310":null,"GO:0004314":null,"GO:0004315":null,"GO:0004325":null,"GO:0004326":null,"GO:0004331":null,"GO:0004332":null,"GO:0004333":null,"GO:0004335":null,"GO:0004337":null,"GO:0004340":null,"GO:0004343":null,"GO:0004347":null,"GO:0004349":null,"GO:0004350":null,"GO:0004351":null,"GO:0004354":null,"GO:0004356":null,"GO:0004357":null,"GO:0004359":null,"GO:0004360":null,"GO:0004362":null,"GO:0004363":null,"GO:0004365":null,"GO:0004366":null,"GO:0004371":null,"GO:0004372":null,"GO:0004375":null,"GO:0004377":null,"GO:0004379":null,"GO:0004382":null,"GO:0004385":null,"GO:0004386":null,"GO:0004399":null,"GO:0004401":null,"GO:0004408":null,"GO:0004410":null,"GO:0004412":null,"GO:0004414":null,"GO:0004416":null,"GO:0004418":null,"GO:0004421":null,"GO:0004422":null,"GO:0004424":null,"GO:0004425":null,"GO:0004427":null,"GO:0004430":null,"GO:0004435":null,"GO:0004439":null,"GO:0004449":null,"GO:0004450":null,"GO:0004452":null,"GO:0004455":null,"GO:0004458":null,"GO:0004471":null,"GO:0004475":null,"GO:0004476":null,"GO:0004477":null,"GO:0004478":null,"GO:0004479":null,"GO:0004484":null,"GO:0004487":null,"GO:0004488":null,"GO:0004496":null,"GO:0004506":null,"GO:0004515":null,"GO:0004516":null,"GO:0004518":null,"GO:0004519":null,"GO:0004521":null,"GO:0004523":null,"GO:0004526":null,"GO:0004534":null,"GO:0004535":null,"GO:0004550":null,"GO:0004553":null,"GO:0004555":null,"GO:0004568":null,"GO:0004573":null,"GO:0004575":null,"GO:0004577":null,"GO:0004579":null,"GO:0004582":null,"GO:0004585":null,"GO:0004586":null,"GO:0004587":null,"GO:0004588":null,"GO:0004590":null,"GO:0004591":null,"GO:0004592":null,"GO:0004594":null,"GO:0004596":null,"GO:0004604":null,"GO:0004605":null,"GO:0004608":null,"GO:0004609":null,"GO:0004610":null,"GO:0004614":null,"GO:0004616":null,"GO:0004620":null,"GO:0004622":null,"GO:0004623":null,"GO:0004630":null,"GO:0004631":null,"GO:0004632":null,"GO:0004637":null,"GO:0004639":null,"GO:0004640":null,"GO:0004641":null,"GO:0004642":null,"GO:0004643":null,"GO:0004644":null,"GO:0004648":null,"GO:0004651":null,"GO:0004655":null,"GO:0004657":null,"GO:0004660":null,"GO:0004662":null,"GO:0004663":null,"GO:0004664":null,"GO:0004671":null,"GO:0004672":null,"GO:0004674":null,"GO:0004683":null,"GO:0004691":null,"GO:0004693":null,"GO:0004694":null,"GO:0004707":null,"GO:0004708":null,"GO:0004713":null,"GO:0004721":null,"GO:0004722":null,"GO:0004725":null,"GO:0004731":null,"GO:0004733":null,"GO:0004735":null,"GO:0004736":null,"GO:0004737":null,"GO:0004739":null,"GO:0004741":null,"GO:0004742":null,"GO:0004743":null,"GO:0004746":null,"GO:0004748":null,"GO:0004749":null,"GO:0004750":null,"GO:0004751":null,"GO:0004758":null,"GO:0004766":null,"GO:0004768":null,"GO:0004775":null,"GO:0004777":null,"GO:0004781":null,"GO:0004783":null,"GO:0004784":null,"GO:0004788":null,"GO:0004789":null,"GO:0004791":null,"GO:0004792":null,"GO:0004794":null,"GO:0004795":null,"GO:0004798":null,"GO:0004799":null,"GO:0004801":null,"GO:0004802":null,"GO:0004805":null,"GO:0004806":null,"GO:0004814":null,"GO:0004815":null,"GO:0004817":null,"GO:0004818":null,"GO:0004820":null,"GO:0004821":null,"GO:0004822":null,"GO:0004823":null,"GO:0004824":null,"GO:0004825":null,"GO:0004826":null,"GO:0004827":null,"GO:0004828":null,"GO:0004829":null,"GO:0004830":null,"GO:0004831":null,"GO:0004832":null,"GO:0004834":null,"GO:0004839":null,"GO:0004843":null,"GO:0004844":null,"GO:0004846":null,"GO:0004849":null,"GO:0004851":null,"GO:0004852":null,"GO:0004853":null,"GO:0004862":null,"GO:0004864":null,"GO:0004865":null,"GO:0005047":null,"GO:0005048":null,"GO:0005049":null,"GO:0005052":null,"GO:0005053":null,"GO:0005078":null,"GO:0005085":null,"GO:0005092":null,"GO:0005093":null,"GO:0005096":null,"GO:0005102":null,"GO:0005198":null,"GO:0005200":null,"GO:0005227":null,"GO:0005254":null,"GO:0005262":null,"GO:0005290":null,"GO:0005302":null,"GO:0005313":null,"GO:0005315":null,"GO:0005351":null,"GO:0005366":null,"GO:0005371":null,"GO:0005384":null,"GO:0005385":null,"GO:0005388":null,"GO:0005458":null,"GO:0005459":null,"GO:0005460":null,"GO:0005462":null,"GO:0005483":null,"GO:0005484":null,"GO:0005506":null,"GO:0005507":null,"GO:0005509":null,"GO:0005516":null,"GO:0005524":null,"GO:0005525":null,"GO:0005543":null,"GO:0005545":null,"GO:0005546":null,"GO:0005576":null,"GO:0005634":null,"GO:0005635":null,"GO:0005637":null,"GO:0005643":null,"GO:0005654":null,"GO:0005655":null,"GO:0005658":null,"GO:0005664":null,"GO:0005665":null,"GO:0005666":null,"GO:0005667":null,"GO:0005669":null,"GO:0005672":null,"GO:0005673":null,"GO:0005674":null,"GO:0005675":null,"GO:0005680":null,"GO:0005681":null,"GO:0005682":null,"GO:0005684":null,"GO:0005685":null,"GO:0005686":null,"GO:0005687":null,"GO:0005688":null,"GO:0005730":null,"GO:0005732":null,"GO:0005736":null,"GO:0005737":null,"GO:0005739":null,"GO:0005740":null,"GO:0005741":null,"GO:0005742":null,"GO:0005743":null,"GO:0005744":null,"GO:0005749":null,"GO:0005750":null,"GO:0005751":null,"GO:0005754":null,"GO:0005758":null,"GO:0005759":null,"GO:0005762":null,"GO:0005763":null,"GO:0005768":null,"GO:0005769":null,"GO:0005770":null,"GO:0005771":null,"GO:0005774":null,"GO:0005776":null,"GO:0005777":null,"GO:0005778":null,"GO:0005782":null,"GO:0005783":null,"GO:0005784":null,"GO:0005786":null,"GO:0005787":null,"GO:0005788":null,"GO:0005789":null,"GO:0005793":null,"GO:0005794":null,"GO:0005795":null,"GO:0005797":null,"GO:0005801":null,"GO:0005802":null,"GO:0005811":null,"GO:0005829":null,"GO:0005832":null,"GO:0005835":null,"GO:0005846":null,"GO:0005847":null,"GO:0005850":null,"GO:0005851":null,"GO:0005854":null,"GO:0005868":null,"GO:0005871":null,"GO:0005874":null,"GO:0005876":null,"GO:0005881":null,"GO:0005884":null,"GO:0005885":null,"GO:0005886":null,"GO:0005891":null,"GO:0005905":null,"GO:0005938":null,"GO:0005945":null,"GO:0005946":null,"GO:0005948":null,"GO:0005951":null,"GO:0005952":null,"GO:0005953":null,"GO:0005955":null,"GO:0005956":null,"GO:0005960":null,"GO:0005965":null,"GO:0005967":null,"GO:0005968":null,"GO:0005971":null,"GO:0005987":null,"GO:0005992":null,"GO:0005993":null,"GO:0006002":null,"GO:0006003":null,"GO:0006006":null,"GO:0006012":null,"GO:0006013":null,"GO:0006014":null,"GO:0006015":null,"GO:0006020":null,"GO:0006038":null,"GO:0006048":null,"GO:0006062":null,"GO:0006066":null,"GO:0006078":null,"GO:0006084":null,"GO:0006086":null,"GO:0006090":null,"GO:0006099":null,"GO:0006102":null,"GO:0006104":null,"GO:0006105":null,"GO:0006106":null,"GO:0006107":null,"GO:0006108":null,"GO:0006116":null,"GO:0006122":null,"GO:0006123":null,"GO:0006144":null,"GO:0006145":null,"GO:0006152":null,"GO:0006164":null,"GO:0006166":null,"GO:0006168":null,"GO:0006177":null,"GO:0006183":null,"GO:0006189":null,"GO:0006190":null,"GO:0006206":null,"GO:0006207":null,"GO:0006225":null,"GO:0006226":null,"GO:0006227":null,"GO:0006228":null,"GO:0006231":null,"GO:0006233":null,"GO:0006235":null,"GO:0006256":null,"GO:0006264":null,"GO:0006265":null,"GO:0006272":null,"GO:0006281":null,"GO:0006283":null,"GO:0006284":null,"GO:0006285":null,"GO:0006287":null,"GO:0006289":null,"GO:0006297":null,"GO:0006298":null,"GO:0006302":null,"GO:0006312":null,"GO:0006335":null,"GO:0006338":null,"GO:0006355":null,"GO:0006356":null,"GO:0006357":null,"GO:0006359":null,"GO:0006360":null,"GO:0006361":null,"GO:0006362":null,"GO:0006364":null,"GO:0006366":null,"GO:0006367":null,"GO:0006369":null,"GO:0006370":null,"GO:0006376":null,"GO:0006384":null,"GO:0006388":null,"GO:0006400":null,"GO:0006401":null,"GO:0006402":null,"GO:0006405":null,"GO:0006406":null,"GO:0006409":null,"GO:0006413":null,"GO:0006415":null,"GO:0006422":null,"GO:0006423":null,"GO:0006424":null,"GO:0006427":null,"GO:0006428":null,"GO:0006429":null,"GO:0006430":null,"GO:0006431":null,"GO:0006432":null,"GO:0006433":null,"GO:0006434":null,"GO:0006435":null,"GO:0006436":null,"GO:0006437":null,"GO:0006450":null,"GO:0006457":null,"GO:0006458":null,"GO:0006465":null,"GO:0006486":null,"GO:0006487":null,"GO:0006488":null,"GO:0006490":null,"GO:0006491":null,"GO:0006493":null,"GO:0006505":null,"GO:0006506":null,"GO:0006511":null,"GO:0006515":null,"GO:0006518":null,"GO:0006526":null,"GO:0006528":null,"GO:0006532":null,"GO:0006533":null,"GO:0006535":null,"GO:0006538":null,"GO:0006541":null,"GO:0006542":null,"GO:0006545":null,"GO:0006556":null,"GO:0006564":null,"GO:0006565":null,"GO:0006567":null,"GO:0006571":null,"GO:0006574":null,"GO:0006592":null,"GO:0006597":null,"GO:0006606":null,"GO:0006607":null,"GO:0006611":null,"GO:0006612":null,"GO:0006614":null,"GO:0006616":null,"GO:0006620":null,"GO:0006623":null,"GO:0006624":null,"GO:0006627":null,"GO:0006631":null,"GO:0006633":null,"GO:0006635":null,"GO:0006636":null,"GO:0006646":null,"GO:0006654":null,"GO:0006656":null,"GO:0006661":null,"GO:0006665":null,"GO:0006666":null,"GO:0006673":null,"GO:0006696":null,"GO:0006729":null,"GO:0006734":null,"GO:0006741":null,"GO:0006742":null,"GO:0006744":null,"GO:0006747":null,"GO:0006749":null,"GO:0006750":null,"GO:0006751":null,"GO:0006780":null,"GO:0006782":null,"GO:0006783":null,"GO:0006784":null,"GO:0006797":null,"GO:0006798":null,"GO:0006808":null,"GO:0006843":null,"GO:0006850":null,"GO:0006874":null,"GO:0006878":null,"GO:0006879":null,"GO:0006880":null,"GO:0006882":null,"GO:0006886":null,"GO:0006887":null,"GO:0006888":null,"GO:0006890":null,"GO:0006891":null,"GO:0006892":null,"GO:0006893":null,"GO:0006895":null,"GO:0006896":null,"GO:0006897":null,"GO:0006900":null,"GO:0006904":null,"GO:0006906":null,"GO:0006914":null,"GO:0006974":null,"GO:0006998":null,"GO:0006999":null,"GO:0007004":null,"GO:0007005":null,"GO:0007007":null,"GO:0007017":null,"GO:0007018":null,"GO:0007021":null,"GO:0007030":null,"GO:0007031":null,"GO:0007032":null,"GO:0007033":null,"GO:0007034":null,"GO:0007035":null,"GO:0007039":null,"GO:0007052":null,"GO:0007059":null,"GO:0007064":null,"GO:0007076":null,"GO:0007091":null,"GO:0007095":null,"GO:0007096":null,"GO:0007131":null,"GO:0007163":null,"GO:0007165":null,"GO:0007186":null,"GO:0007346":null,"GO:0008017":null,"GO:0008033":null,"GO:0008053":null,"GO:0008080":null,"GO:0008081":null,"GO:0008097":null,"GO:0008106":null,"GO:0008108":null,"GO:0008139":null,"GO:0008142":null,"GO:0008153":null,"GO:0008160":null,"GO:0008168":null,"GO:0008175":null,"GO:0008176":null,"GO:0008177":null,"GO:0008180":null,"GO:0008187":null,"GO:0008193":null,"GO:0008195":null,"GO:0008198":null,"GO:0008237":null,"GO:0008239":null,"GO:0008240":null,"GO:0008250":null,"GO:0008270":null,"GO:0008289":null,"GO:0008290":null,"GO:0008295":null,"GO:0008296":null,"GO:0008298":null,"GO:0008299":null,"GO:0008308":null,"GO:0008310":null,"GO:0008311":null,"GO:0008312":null,"GO:0008320":null,"GO:0008324":null,"GO:0008330":null,"GO:0008331":null,"GO:0008374":null,"GO:0008379":null,"GO:0008408":null,"GO:0008409":null,"GO:0008412":null,"GO:0008418":null,"GO:0008419":null,"GO:0008420":null,"GO:0008429":null,"GO:0008440":null,"GO:0008441":null,"GO:0008444":null,"GO:0008469":null,"GO:0008474":null,"GO:0008477":null,"GO:0008478":null,"GO:0008479":null,"GO:0008486":null,"GO:0008506":null,"GO:0008517":null,"GO:0008519":null,"GO:0008526":null,"GO:0008531":null,"GO:0008540":null,"GO:0008541":null,"GO:0008553":null,"GO:0008554":null,"GO:0008574":null,"GO:0008597":null,"GO:0008614":null,"GO:0008615":null,"GO:0008623":null,"GO:0008649":null,"GO:0008650":null,"GO:0008654":null,"GO:0008682":null,"GO:0008686":null,"GO:0008720":null,"GO:0008721":null,"GO:0008732":null,"GO:0008798":null,"GO:0008821":null,"GO:0008841":null,"GO:0008865":null,"GO:0008892":null,"GO:0008897":null,"GO:0008898":null,"GO:0008902":null,"GO:0008934":null,"GO:0008972":null,"GO:0008973":null,"GO:0008998":null,"GO:0009001":null,"GO:0009051":null,"GO:0009052":null,"GO:0009055":null,"GO:0009073":null,"GO:0009074":null,"GO:0009086":null,"GO:0009088":null,"GO:0009089":null,"GO:0009090":null,"GO:0009092":null,"GO:0009094":null,"GO:0009097":null,"GO:0009098":null,"GO:0009099":null,"GO:0009102":null,"GO:0009107":null,"GO:0009113":null,"GO:0009117":null,"GO:0009134":null,"GO:0009141":null,"GO:0009159":null,"GO:0009228":null,"GO:0009229":null,"GO:0009231":null,"GO:0009240":null,"GO:0009251":null,"GO:0009265":null,"GO:0009267":null,"GO:0009272":null,"GO:0009277":null,"GO:0009298":null,"GO:0009314":null,"GO:0009328":null,"GO:0009361":null,"GO:0009378":null,"GO:0009383":null,"GO:0009395":null,"GO:0009396":null,"GO:0009398":null,"GO:0009435":null,"GO:0009443":null,"GO:0009898":null,"GO:0009922":null,"GO:0009927":null,"GO:0009972":null,"GO:0009982":null,"GO:0009986":null,"GO:0010008":null,"GO:0010121":null,"GO:0010133":null,"GO:0010134":null,"GO:0010142":null,"GO:0010181":null,"GO:0010265":null,"GO:0010273":null,"GO:0010309":null,"GO:0010468":null,"GO:0010485":null,"GO:0010494":null,"GO:0010499":null,"GO:0010506":null,"GO:0010508":null,"GO:0010521":null,"GO:0010833":null,"GO:0010961":null,"GO:0010971":null,"GO:0010992":null,"GO:0010997":null,"GO:0012506":null,"GO:0012507":null,"GO:0015035":null,"GO:0015038":null,"GO:0015086":null,"GO:0015093":null,"GO:0015095":null,"GO:0015114":null,"GO:0015116":null,"GO:0015123":null,"GO:0015171":null,"GO:0015189":null,"GO:0015194":null,"GO:0015204":null,"GO:0015205":null,"GO:0015218":null,"GO:0015228":null,"GO:0015230":null,"GO:0015233":null,"GO:0015297":null,"GO:0015343":null,"GO:0015369":null,"GO:0015385":null,"GO:0015386":null,"GO:0015421":null,"GO:0015489":null,"GO:0015606":null,"GO:0015616":null,"GO:0015630":null,"GO:0015662":null,"GO:0015677":null,"GO:0015742":null,"GO:0015847":null,"GO:0015851":null,"GO:0015866":null,"GO:0015926":null,"GO:0015937":null,"GO:0015938":null,"GO:0015940":null,"GO:0016018":null,"GO:0016020":null,"GO:0016024":null,"GO:0016036":null,"GO:0016040":null,"GO:0016075":null,"GO:0016125":null,"GO:0016149":null,"GO:0016192":null,"GO:0016197":null,"GO:0016208":null,"GO:0016212":null,"GO:0016226":null,"GO:0016233":null,"GO:0016236":null,"GO:0016237":null,"GO:0016239":null,"GO:0016251":null,"GO:0016255":null,"GO:0016272":null,"GO:0016279":null,"GO:0016281":null,"GO:0016282":null,"GO:0016287":null,"GO:0016298":null,"GO:0016303":null,"GO:0016308":null,"GO:0016314":null,"GO:0016320":null,"GO:0016363":null,"GO:0016410":null,"GO:0016428":null,"GO:0016433":null,"GO:0016460":null,"GO:0016480":null,"GO:0016491":null,"GO:0016504":null,"GO:0016514":null,"GO:0016538":null,"GO:0016558":null,"GO:0016559":null,"GO:0016560":null,"GO:0016586":null,"GO:0016592":null,"GO:0016593":null,"GO:0016594":null,"GO:0016602":null,"GO:0016604":null,"GO:0016607":null,"GO:0016616":null,"GO:0016618":null,"GO:0016651":null,"GO:0016706":null,"GO:0016756":null,"GO:0016788":null,"GO:0016791":null,"GO:0016887":null,"GO:0016891":null,"GO:0016925":null,"GO:0016929":null,"GO:0016971":null,"GO:0016973":null,"GO:0016992":null,"GO:0017017":null,"GO:0017025":null,"GO:0017050":null,"GO:0017056":null,"GO:0017057":null,"GO:0017061":null,"GO:0017069":null,"GO:0017070":null,"GO:0017101":null,"GO:0017102":null,"GO:0017108":null,"GO:0017109":null,"GO:0017111":null,"GO:0017116":null,"GO:0017118":null,"GO:0017119":null,"GO:0017121":null,"GO:0017125":null,"GO:0017128":null,"GO:0017157":null,"GO:0017168":null,"GO:0017176":null,"GO:0017177":null,"GO:0017178":null,"GO:0017183":null,"GO:0018279":null,"GO:0018423":null,"GO:0018444":null,"GO:0018773":null,"GO:0019003":null,"GO:0019005":null,"GO:0019135":null,"GO:0019158":null,"GO:0019166":null,"GO:0019171":null,"GO:0019172":null,"GO:0019239":null,"GO:0019240":null,"GO:0019243":null,"GO:0019264":null,"GO:0019287":null,"GO:0019346":null,"GO:0019354":null,"GO:0019367":null,"GO:0019379":null,"GO:0019408":null,"GO:0019432":null,"GO:0019433":null,"GO:0019464":null,"GO:0019478":null,"GO:0019509":null,"GO:0019544":null,"GO:0019547":null,"GO:0019563":null,"GO:0019628":null,"GO:0019676":null,"GO:0019677":null,"GO:0019693":null,"GO:0019702":null,"GO:0019706":null,"GO:0019773":null,"GO:0019776":null,"GO:0019778":null,"GO:0019779":null,"GO:0019781":null,"GO:0019784":null,"GO:0019829":null,"GO:0019843":null,"GO:0019878":null,"GO:0019898":null,"GO:0019902":null,"GO:0019905":null,"GO:0019941":null,"GO:0019948":null,"GO:0019988":null,"GO:0020037":null,"GO:0022417":null,"GO:0022618":null,"GO:0022625":null,"GO:0022627":null,"GO:0022857":null,"GO:0030001":null,"GO:0030007":null,"GO:0030010":null,"GO:0030011":null,"GO:0030015":null,"GO:0030026":null,"GO:0030036":null,"GO:0030042":null,"GO:0030050":null,"GO:0030060":null,"GO:0030100":null,"GO:0030121":null,"GO:0030122":null,"GO:0030123":null,"GO:0030125":null,"GO:0030126":null,"GO:0030127":null,"GO:0030133":null,"GO:0030134":null,"GO:0030136":null,"GO:0030139":null,"GO:0030145":null,"GO:0030148":null,"GO:0030170":null,"GO:0030258":null,"GO:0030267":null,"GO:0030272":null,"GO:0030276":null,"GO:0030289":null,"GO:0030295":null,"GO:0030332":null,"GO:0030337":null,"GO:0030388":null,"GO:0030422":null,"GO:0030427":null,"GO:0030466":null,"GO:0030479":null,"GO:0030488":null,"GO:0030490":null,"GO:0030497":null,"GO:0030515":null,"GO:0030544":null,"GO:0030552":null,"GO:0030586":null,"GO:0030619":null,"GO:0030620":null,"GO:0030621":null,"GO:0030623":null,"GO:0030627":null,"GO:0030628":null,"GO:0030674":null,"GO:0030686":null,"GO:0030687":null,"GO:0030688":null,"GO:0030690":null,"GO:0030691":null,"GO:0030692":null,"GO:0030695":null,"GO:0030833":null,"GO:0030870":null,"GO:0030896":null,"GO:0030904":null,"GO:0030905":null,"GO:0030907":null,"GO:0030915":null,"GO:0030942":null,"GO:0030943":null,"GO:0030950":null,"GO:0030956":null,"GO:0030968":null,"GO:0030970":null,"GO:0030976":null,"GO:0031011":null,"GO:0031030":null,"GO:0031032":null,"GO:0031071":null,"GO:0031072":null,"GO:0031080":null,"GO:0031087":null,"GO:0031097":null,"GO:0031106":null,"GO:0031118":null,"GO:0031119":null,"GO:0031120":null,"GO:0031122":null,"GO:0031123":null,"GO:0031145":null,"GO:0031146":null,"GO:0031167":null,"GO:0031201":null,"GO:0031204":null,"GO:0031207":null,"GO:0031210":null,"GO:0031211":null,"GO:0031250":null,"GO:0031251":null,"GO:0031261":null,"GO:0031262":null,"GO:0031267":null,"GO:0031297":null,"GO:0031298":null,"GO:0031369":null,"GO:0031380":null,"GO:0031386":null,"GO:0031389":null,"GO:0031390":null,"GO:0031391":null,"GO:0031410":null,"GO:0031415":null,"GO:0031416":null,"GO:0031417":null,"GO:0031428":null,"GO:0031429":null,"GO:0031431":null,"GO:0031463":null,"GO:0031468":null,"GO:0031490":null,"GO:0031491":null,"GO:0031499":null,"GO:0031505":null,"GO:0031507":null,"GO:0031510":null,"GO:0031515":null,"GO:0031533":null,"GO:0031573":null,"GO:0031588":null,"GO:0031591":null,"GO:0031593":null,"GO:0031623":null,"GO:0031624":null,"GO:0031625":null,"GO:0031902":null,"GO:0031930":null,"GO:0031931":null,"GO:0031932":null,"GO:0031934":null,"GO:0031942":null,"GO:0031956":null,"GO:0031965":null,"GO:0031982":null,"GO:0031985":null,"GO:0031991":null,"GO:0032008":null,"GO:0032036":null,"GO:0032040":null,"GO:0032045":null,"GO:0032049":null,"GO:0032050":null,"GO:0032051":null,"GO:0032126":null,"GO:0032153":null,"GO:0032182":null,"GO:0032210":null,"GO:0032220":null,"GO:0032221":null,"GO:0032263":null,"GO:0032264":null,"GO:0032265":null,"GO:0032266":null,"GO:0032299":null,"GO:0032301":null,"GO:0032357":null,"GO:0032366":null,"GO:0032389":null,"GO:0032432":null,"GO:0032435":null,"GO:0032436":null,"GO:0032447":null,"GO:0032454":null,"GO:0032456":null,"GO:0032468":null,"GO:0032511":null,"GO:0032527":null,"GO:0032541":null,"GO:0032542":null,"GO:0032543":null,"GO:0032545":null,"GO:0032786":null,"GO:0032790":null,"GO:0032807":null,"GO:0032865":null,"GO:0032889":null,"GO:0032931":null,"GO:0032934":null,"GO:0032936":null,"GO:0032955":null,"GO:0032956":null,"GO:0032958":null,"GO:0032968":null,"GO:0032974":null,"GO:0032977":null,"GO:0032979":null,"GO:0033063":null,"GO:0033065":null,"GO:0033106":null,"GO:0033149":null,"GO:0033192":null,"GO:0033204":null,"GO:0033229":null,"GO:0033254":null,"GO:0033309":null,"GO:0033314":null,"GO:0033353":null,"GO:0033387":null,"GO:0033503":null,"GO:0033528":null,"GO:0033550":null,"GO:0033553":null,"GO:0033557":null,"GO:0033565":null,"GO:0033573":null,"GO:0033588":null,"GO:0033596":null,"GO:0033615":null,"GO:0033617":null,"GO:0033698":null,"GO:0033819":null,"GO:0033857":null,"GO:0033862":null,"GO:0033962":null,"GO:0034038":null,"GO:0034039":null,"GO:0034044":null,"GO:0034045":null,"GO:0034058":null,"GO:0034063":null,"GO:0034066":null,"GO:0034080":null,"GO:0034085":null,"GO:0034088":null,"GO:0034098":null,"GO:0034198":null,"GO:0034203":null,"GO:0034221":null,"GO:0034236":null,"GO:0034245":null,"GO:0034247":null,"GO:0034271":null,"GO:0034272":null,"GO:0034274":null,"GO:0034314":null,"GO:0034316":null,"GO:0034353":null,"GO:0034355":null,"GO:0034356":null,"GO:0034388":null,"GO:0034398":null,"GO:0034399":null,"GO:0034402":null,"GO:0034424":null,"GO:0034431":null,"GO:0034432":null,"GO:0034450":null,"GO:0034455":null,"GO:0034456":null,"GO:0034457":null,"GO:0034458":null,"GO:0034462":null,"GO:0034473":null,"GO:0034475":null,"GO:0034476":null,"GO:0034477":null,"GO:0034486":null,"GO:0034496":null,"GO:0034498":null,"GO:0034506":null,"GO:0034511":null,"GO:0034513":null,"GO:0034514":null,"GO:0034515":null,"GO:0034517":null,"GO:0034551":null,"GO:0034553":null,"GO:0034599":null,"GO:0034625":null,"GO:0034647":null,"GO:0034657":null,"GO:0034663":null,"GO:0034715":null,"GO:0034719":null,"GO:0034727":null,"GO:0034737":null,"GO:0034967":null,"GO:0034976":null,"GO:0034982":null,"GO:0034992":null,"GO:0035064":null,"GO:0035091":null,"GO:0035101":null,"GO:0035145":null,"GO:0035267":null,"GO:0035299":null,"GO:0035336":null,"GO:0035361":null,"GO:0035371":null,"GO:0035485":null,"GO:0035493":null,"GO:0035494":null,"GO:0035529":null,"GO:0035556":null,"GO:0035591":null,"GO:0035615":null,"GO:0035621":null,"GO:0035657":null,"GO:0035838":null,"GO:0035861":null,"GO:0035925":null,"GO:0035965":null,"GO:0035999":null,"GO:0036002":null,"GO:0036042":null,"GO:0036088":null,"GO:0036092":null,"GO:0036149":null,"GO:0036228":null,"GO:0036261":null,"GO:0036286":null,"GO:0036297":null,"GO:0036435":null,"GO:0036498":null,"GO:0036503":null,"GO:0038023":null,"GO:0038066":null,"GO:0038203":null,"GO:0040031":null,"GO:0042026":null,"GO:0042124":null,"GO:0042134":null,"GO:0042138":null,"GO:0042144":null,"GO:0042147":null,"GO:0042148":null,"GO:0042149":null,"GO:0042162":null,"GO:0042171":null,"GO:0042175":null,"GO:0042254":null,"GO:0042273":null,"GO:0042274":null,"GO:0042276":null,"GO:0042277":null,"GO:0042281":null,"GO:0042283":null,"GO:0042284":null,"GO:0042292":null,"GO:0042392":null,"GO:0042393":null,"GO:0042407":null,"GO:0042450":null,"GO:0042555":null,"GO:0042565":null,"GO:0042602":null,"GO:0042645":null,"GO:0042709":null,"GO:0042720":null,"GO:0042721":null,"GO:0042729":null,"GO:0042744":null,"GO:0042759":null,"GO:0042761":null,"GO:0042765":null,"GO:0042790":null,"GO:0042791":null,"GO:0042797":null,"GO:0042823":null,"GO:0042906":null,"GO:0042907":null,"GO:0042937":null,"GO:0042973":null,"GO:0042989":null,"GO:0043001":null,"GO:0043007":null,"GO:0043022":null,"GO:0043023":null,"GO:0043024":null,"GO:0043048":null,"GO:0043111":null,"GO:0043115":null,"GO:0043130":null,"GO:0043137":null,"GO:0043138":null,"GO:0043139":null,"GO:0043161":null,"GO:0043171":null,"GO:0043291":null,"GO:0043295":null,"GO:0043328":null,"GO:0043332":null,"GO:0043335":null,"GO:0043408":null,"GO:0043456":null,"GO:0043495":null,"GO:0043504":null,"GO:0043529":null,"GO:0043539":null,"GO:0043541":null,"GO:0043564":null,"GO:0043596":null,"GO:0043599":null,"GO:0043614":null,"GO:0043625":null,"GO:0043626":null,"GO:0043682":null,"GO:0043812":null,"GO:0043813":null,"GO:0043829":null,"GO:0043874":null,"GO:0043928":null,"GO:0043998":null,"GO:0044183":null,"GO:0044208":null,"GO:0044209":null,"GO:0044255":null,"GO:0044284":null,"GO:0044571":null,"GO:0044611":null,"GO:0044613":null,"GO:0044614":null,"GO:0044695":null,"GO:0044732":null,"GO:0044773":null,"GO:0044778":null,"GO:0044804":null,"GO:0044820":null,"GO:0045002":null,"GO:0045003":null,"GO:0045004":null,"GO:0045016":null,"GO:0045022":null,"GO:0045025":null,"GO:0045039":null,"GO:0045040":null,"GO:0045041":null,"GO:0045056":null,"GO:0045116":null,"GO:0045134":null,"GO:0045140":null,"GO:0045145":null,"GO:0045261":null,"GO:0045292":null,"GO:0045324":null,"GO:0045332":null,"GO:0045337":null,"GO:0045338":null,"GO:0045454":null,"GO:0045503":null,"GO:0045504":null,"GO:0045540":null,"GO:0045547":null,"GO:0045717":null,"GO:0045719":null,"GO:0045820":null,"GO:0045943":null,"GO:0045944":null,"GO:0045948":null,"GO:0046027":null,"GO:0046033":null,"GO:0046040":null,"GO:0046081":null,"GO:0046084":null,"GO:0046100":null,"GO:0046132":null,"GO:0046166":null,"GO:0046177":null,"GO:0046294":null,"GO:0046316":null,"GO:0046390":null,"GO:0046403":null,"GO:0046404":null,"GO:0046452":null,"GO:0046461":null,"GO:0046464":null,"GO:0046474":null,"GO:0046475":null,"GO:0046512":null,"GO:0046513":null,"GO:0046523":null,"GO:0046540":null,"GO:0046557":null,"GO:0046570":null,"GO:0046580":null,"GO:0046654":null,"GO:0046655":null,"GO:0046705":null,"GO:0046820":null,"GO:0046872":null,"GO:0046901":null,"GO:0046907":null,"GO:0046933":null,"GO:0046938":null,"GO:0046943":null,"GO:0046961":null,"GO:0046970":null,"GO:0046972":null,"GO:0047046":null,"GO:0047184":null,"GO:0047372":null,"GO:0047389":null,"GO:0047429":null,"GO:0047453":null,"GO:0047536":null,"GO:0047555":null,"GO:0047560":null,"GO:0047617":null,"GO:0047631":null,"GO:0047657":null,"GO:0047874":null,"GO:0048015":null,"GO:0048026":null,"GO:0048029":null,"GO:0048038":null,"GO:0048188":null,"GO:0048194":null,"GO:0048205":null,"GO:0048211":null,"GO:0048250":null,"GO:0048254":null,"GO:0048257":null,"GO:0048278":null,"GO:0048280":null,"GO:0048312":null,"GO:0048471":null,"GO:0048476":null,"GO:0048487":null,"GO:0050152":null,"GO:0050185":null,"GO:0050265":null,"GO:0050278":null,"GO:0050291":null,"GO:0050321":null,"GO:0050385":null,"GO:0050483":null,"GO:0050567":null,"GO:0050613":null,"GO:0050660":null,"GO:0050661":null,"GO:0050664":null,"GO:0050667":null,"GO:0050684":null,"GO:0050801":null,"GO:0050833":null,"GO:0051010":null,"GO:0051015":null,"GO:0051016":null,"GO:0051017":null,"GO:0051020":null,"GO:0051072":null,"GO:0051082":null,"GO:0051083":null,"GO:0051087":null,"GO:0051117":null,"GO:0051123":null,"GO:0051131":null,"GO:0051156":null,"GO:0051209":null,"GO:0051228":null,"GO:0051267":null,"GO:0051315":null,"GO:0051377":null,"GO:0051382":null,"GO:0051383":null,"GO:0051453":null,"GO:0051500":null,"GO:0051537":null,"GO:0051539":null,"GO:0051598":null,"GO:0051603":null,"GO:0051639":null,"GO:0051654":null,"GO:0051666":null,"GO:0051724":null,"GO:0051731":null,"GO:0051754":null,"GO:0051787":null,"GO:0051864":null,"GO:0051879":null,"GO:0051996":null,"GO:0051999":null,"GO:0052381":null,"GO:0052689":null,"GO:0052735":null,"GO:0052856":null,"GO:0052907":null,"GO:0052925":null,"GO:0052929":null,"GO:0055037":null,"GO:0055085":null,"GO:0055087":null,"GO:0055088":null,"GO:0055129":null,"GO:0060090":null,"GO:0060172":null,"GO:0060213":null,"GO:0060237":null,"GO:0061025":null,"GO:0061133":null,"GO:0061136":null,"GO:0061186":null,"GO:0061188":null,"GO:0061459":null,"GO:0061503":null,"GO:0061504":null,"GO:0061509":null,"GO:0061575":null,"GO:0061578":null,"GO:0061608":null,"GO:0061617":null,"GO:0061621":null,"GO:0061630":null,"GO:0061631":null,"GO:0061632":null,"GO:0061640":null,"GO:0061656":null,"GO:0061665":null,"GO:0061673":null,"GO:0061685":null,"GO:0061700":null,"GO:0061709":null,"GO:0061775":null,"GO:0061817":null,"GO:0070006":null,"GO:0070034":null,"GO:0070037":null,"GO:0070042":null,"GO:0070063":null,"GO:0070086":null,"GO:0070095":null,"GO:0070096":null,"GO:0070124":null,"GO:0070125":null,"GO:0070126":null,"GO:0070139":null,"GO:0070150":null,"GO:0070158":null,"GO:0070180":null,"GO:0070181":null,"GO:0070183":null,"GO:0070210":null,"GO:0070221":null,"GO:0070224":null,"GO:0070273":null,"GO:0070274":null,"GO:0070319":null,"GO:0070336":null,"GO:0070370":null,"GO:0070390":null,"GO:0070402":null,"GO:0070403":null,"GO:0070413":null,"GO:0070475":null,"GO:0070476":null,"GO:0070478":null,"GO:0070545":null,"GO:0070577":null,"GO:0070588":null,"GO:0070600":null,"GO:0070626":null,"GO:0070628":null,"GO:0070651":null,"GO:0070681":null,"GO:0070682":null,"GO:0070692":null,"GO:0070694":null,"GO:0070761":null,"GO:0070772":null,"GO:0070773":null,"GO:0070824":null,"GO:0070847":null,"GO:0070860":null,"GO:0070863":null,"GO:0070898":null,"GO:0070899":null,"GO:0070901":null,"GO:0070905":null,"GO:0070914":null,"GO:0070916":null,"GO:0070917":null,"GO:0070935":null,"GO:0070941":null,"GO:0070966":null,"GO:0070971":null,"GO:0070973":null,"GO:0070985":null,"GO:0070987":null,"GO:0071004":null,"GO:0071006":null,"GO:0071007":null,"GO:0071008":null,"GO:0071011":null,"GO:0071013":null,"GO:0071014":null,"GO:0071020":null,"GO:0071021":null,"GO:0071028":null,"GO:0071031":null,"GO:0071034":null,"GO:0071035":null,"GO:0071036":null,"GO:0071037":null,"GO:0071038":null,"GO:0071039":null,"GO:0071040":null,"GO:0071042":null,"GO:0071044":null,"GO:0071051":null,"GO:0071074":null,"GO:0071164":null,"GO:0071171":null,"GO:0071218":null,"GO:0071244":null,"GO:0071421":null,"GO:0071439":null,"GO:0071528":null,"GO:0071540":null,"GO:0071541":null,"GO:0071543":null,"GO:0071561":null,"GO:0071562":null,"GO:0071577":null,"GO:0071586":null,"GO:0071590":null,"GO:0071592":null,"GO:0071596":null,"GO:0071630":null,"GO:0071765":null,"GO:0071805":null,"GO:0071816":null,"GO:0071846":null,"GO:0071885":null,"GO:0071913":null,"GO:0071916":null,"GO:0071932":null,"GO:0071933":null,"GO:0071942":null,"GO:0071944":null,"GO:0071949":null,"GO:0071966":null,"GO:0072318":null,"GO:0072334":null,"GO:0072344":null,"GO:0072354":null,"GO:0072488":null,"GO:0072542":null,"GO:0072546":null,"GO:0072583":null,"GO:0072657":null,"GO:0072659":null,"GO:0072670":null,"GO:0072686":null,"GO:0080008":null,"GO:0080025":null,"GO:0080132":null,"GO:0080139":null,"GO:0089701":null,"GO:0089721":null,"GO:0090110":null,"GO:0090114":null,"GO:0090158":null,"GO:0090443":null,"GO:0090575":null,"GO:0090599":null,"GO:0097020":null,"GO:0097036":null,"GO:0097038":null,"GO:0097157":null,"GO:0097177":null,"GO:0097268":null,"GO:0097352":null,"GO:0097361":null,"GO:0097422":null,"GO:0097428":null,"GO:0097510":null,"GO:0097550":null,"GO:0097552":null,"GO:0097602":null,"GO:0097720":null,"GO:0098505":null,"GO:0098703":null,"GO:0098717":null,"GO:0098849":null,"GO:0098863":null,"GO:0101005":null,"GO:0101030":null,"GO:0106035":null,"GO:0106166":null,"GO:0110031":null,"GO:0110032":null,"GO:0110051":null,"GO:0110155":null,"GO:0120015":null,"GO:0140053":null,"GO:0140107":null,"GO:0140206":null,"GO:0140268":null,"GO:0140278":null,"GO:0140281":null,"GO:0140570":null,"GO:0140658":null,"GO:0140659":null,"GO:1901255":null,"GO:1901565":null,"GO:1901907":null,"GO:1901909":null,"GO:1901911":null,"GO:1902369":null,"GO:1902476":null,"GO:1902500":null,"GO:1902600":null,"GO:1902626":null,"GO:1902716":null,"GO:1902929":null,"GO:1902975":null,"GO:1902977":null,"GO:1902981":null,"GO:1902983":null,"GO:1903189":null,"GO:1903425":null,"GO:1903457":null,"GO:1903461":null,"GO:1903475":null,"GO:1903479":null,"GO:1903600":null,"GO:1904161":null,"GO:1904257":null,"GO:1904262":null,"GO:1904263":null,"GO:1904423":null,"GO:1904679":null,"GO:1904802":null,"GO:1904812":null,"GO:1904947":null,"GO:1990023":null,"GO:1990050":null,"GO:1990070":null,"GO:1990071":null,"GO:1990072":null,"GO:1990112":null,"GO:1990113":null,"GO:1990114":null,"GO:1990115":null,"GO:1990116":null,"GO:1990130":null,"GO:1990189":null,"GO:1990190":null,"GO:1990221":null,"GO:1990259":null,"GO:1990269":null,"GO:1990275":null,"GO:1990304":null,"GO:1990316":null,"GO:1990429":null,"GO:1990446":null,"GO:1990456":null,"GO:1990481":null,"GO:1990519":null,"GO:1990528":null,"GO:1990529":null,"GO:1990536":null,"GO:1990559":null,"GO:1990573":null,"GO:1990575":null,"GO:1990604":null,"GO:1990616":null,"GO:1990625":null,"GO:1990683":null,"GO:1990726":null,"GO:1990757":null,"GO:1990810":null,"GO:1990811":null,"GO:1990825":null,"GO:1990861":null,"GO:1990862":null,"GO:1990883":null,"GO:1990904":null,"GO:2000234":null,"GO:2000767":null},"title":"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.","uniquename":"PMID:21873635"}


