# genes

id: YMR109W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04001":null,"YMR109W":null},"has_protein_features":false,"name":"MYO5","ortholog_annotations":[{"gene_uniquename":"YMR109W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04001","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR109W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04001","reference_uniquename":"PMID:26896847"}],"product":"One of two type I myosin motors; involved in clathrin-mediated endocytosis; activation by TEDS site phosphorylation increases actin gliding, motor activity and ligand-induced endocytosis; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO5 has a paralog, MYO3, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004715","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR109W"}


id: YMR110C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"HFD1","product":"Dehydrogenase involved in ubiquinone and sphingolipid metabolism; converts 4-hydroxybenzaldehyde into 4-hydroxybenzoate for ubiquinone anabolism, hexadecenal to hexadecenoic acid in sphingosine 1-phosphate catabolism; human homolog ALDH3A2, mutated in Sjogren-Larsson syndrome, can rescue yeast hfd1 mutant; human ALDH3A1, but not ALDH3A2, rescues pABA- respiratory growth phenotype of hfd1 null; data suggest that dual functions of Hfd1p have diverged in human ALDH3A1, ALDH3A2","secondary_identifier":"SGD:S000004716","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR110C"}


id: YMR111C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"EUC1","product":"Sequence-specific DNA binding protein; binds to a sequence motif associated with distinct genomic hotspots of non-H2B protein ubiquitylation (ub-hotspots); interacts with Slx5p to recruit the Slx5-Slx8  SUMO-targeted Ub ligase (STUbL) complex to ub-hotspots; deletion prevents ub-hotspot formation and exacerbates heat sensitivity of cells deficient in Rpd3L histone deacetylase complex members; forms nuclear foci upon DNA replication stress","secondary_identifier":"SGD:S000004717","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR111C"}


id: YMR112C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01403":null,"YMR112C":null},"has_protein_features":false,"name":"MED11","ortholog_annotations":[{"gene_uniquename":"YMR112C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01403","reference_uniquename":"PMID:29761456"}],"product":"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential protein","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004718","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR112C"}


id: YMR113W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00529":null,"YMR113W":null},"has_protein_features":false,"name":"FOL3","ortholog_annotations":[{"gene_uniquename":"YMR113W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00529","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR113W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00529","reference_uniquename":"PMID:26896847"}],"product":"Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis; FOL3 has a paralog, RMA1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004719","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR113W"}


id: YMR114C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR114C is not an essential gene","secondary_identifier":"SGD:S000004720","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR114C"}


id: YMR115W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00354":null,"YMR115W":null},"has_protein_features":false,"name":"MGR3","ortholog_annotations":[{"gene_uniquename":"YMR115W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00354","reference_uniquename":"PMID:29761456"}],"product":"Subunit of the mitochondrial (mt) i-AAA protease supercomplex; i-AAA degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004721","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR115W"}


id: YMR116C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05000":null,"YMR116C":null},"has_protein_features":false,"name":"ASC1","ortholog_annotations":[{"gene_uniquename":"YMR116C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05000","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR116C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05000","reference_uniquename":"PMID:26896847"}],"product":"G-protein beta subunit and guanine dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; required to prevent frameshifting at ribosomes stalled at repeated CGA codons; regulates P-body formation induced by replication stress; represses Gcn4p in the absence of amino acid starvation; controls phosphorylation of multiple proteins","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004722","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR116C"}


id: YMR117C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02814":null,"YMR117C":null},"has_protein_features":false,"name":"SPC24","ortholog_annotations":[{"gene_uniquename":"YMR117C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02814","reference_uniquename":"PMID:29761456"}],"product":"Component of the kinetochore-associated Ndc80 complex; involved in chromosome segregation, spindle checkpoint activity, and kinetochore clustering; evolutionarily conserved; other members include Ndc80p, Nuf2p, Spc24p, and Spc25p","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004723","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR117C"}


id: YMR118C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03920":null,"YMR118C":null},"has_protein_features":false,"name":"SHH3","ortholog_annotations":[{"gene_uniquename":"YMR118C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03920","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR118C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03920","reference_uniquename":"PMID:26896847"}],"product":"Putative mitochondrial inner membrane protein of unknown function; although similar to paralogous Sdh3p, Shh3p is not a stoichiometric subunit of either succinate dehydrogenase or of the TIM22 translocase; SHH3 has a paralog, SDH3, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004724","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR118C"}


id: YMR119W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ASI1","product":"Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and regulators of sterol biosynthesis for ubiquitin-mediated degradation; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids","secondary_identifier":"SGD:S000004725","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR119W"}


id: YMR119W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 3' end of ORF ASI1/YMR119W","secondary_identifier":"SGD:S000004726","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR119W-A"}


id: YMR120C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04681":null,"YMR120C":null},"has_protein_features":false,"name":"ADE17","ortholog_annotations":[{"gene_uniquename":"YMR120C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04681","reference_uniquename":"PMID:29761456"}],"product":"Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE17 has a paralog, ADE16, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004727","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR120C"}


id: YMR121C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03919":null,"SJAG_04478":null,"YMR121C":null},"has_protein_features":false,"name":"RPL15B","ortholog_annotations":[{"gene_uniquename":"YMR121C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03919","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR121C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03919","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR121C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04478","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR121C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04478","reference_uniquename":"PMID:29761456"}],"product":"Ribosomal 60S subunit protein L15B; binds to 5.8 S rRNA; homologous to mammalian ribosomal protein L15, no bacterial homolog; RPL15B has a paralog, RPL15A, that arose from the whole genome duplication; relocalizes from nucleus to nucleolus upon DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004728","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR121C"}


id: YMR122C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; conserved among S. cerevisiae strains; YMR122C is not an essential gene","secondary_identifier":"SGD:S000004729","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR122C"}


id: YMR122W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"NCW1","product":"Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and endoplasmic reticulum","secondary_identifier":"SGD:S000007524","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR122W-A"}


id: YMR123W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05306":null,"YMR123W":null},"has_protein_features":false,"name":"PKR1","ortholog_annotations":[{"gene_uniquename":"YMR123W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05306","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR123W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05306","reference_uniquename":"PMID:26896847"}],"product":"V-ATPase assembly factor; functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004730","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR123W"}


id: YMR124W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"EPO1","product":"Protein involved in septin-ER tethering; interacts with ER membrane protein, Scs2p, and Shs1p, a septin ring component, at bud neck to create ER diffusion barrier; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W has a paralog, YLR031W, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004731","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR124W"}


id: YMR125W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04360":null,"YMR125W":null},"has_protein_features":false,"name":"STO1","ortholog_annotations":[{"gene_uniquename":"YMR125W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04360","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR125W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04360","reference_uniquename":"PMID:26896847"}],"product":"Large subunit of the nuclear mRNA cap-binding protein complex; interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004732","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR125W"}


id: YMR126C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"DLT1","product":"Protein of unknown function; mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA)","secondary_identifier":"SGD:S000004733","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR126C"}


id: YMR127C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SAS2","product":"Histone acetyltransferase (HAT) catalytic subunit of the SAS complex; acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family; other members are Sas4p and Sas5p","secondary_identifier":"SGD:S000004734","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR127C"}


id: YMR128W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03077":null,"YMR128W":null},"has_protein_features":false,"name":"ECM16","ortholog_annotations":[{"gene_uniquename":"YMR128W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03077","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR128W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03077","reference_uniquename":"PMID:26896847"}],"product":"Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP; functions with methyltransferase Bud23p; predominantly nucleolar in distribution; required for 18S rRNA synthesis","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004735","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR128W"}


id: YMR129W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01834":null,"YMR129W":null},"has_protein_features":false,"name":"POM152","ortholog_annotations":[{"gene_uniquename":"YMR129W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01834","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR129W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01834","reference_uniquename":"PMID:26896847"}],"product":"Glycoprotein subunit of transmembrane ring of nuclear pore complex; contributes to nucleocytoplasmic transport, nuclear pore complex (NPC) biogenesis and spindle pole body duplication; type II transmembrane protein composed of N-terminal cytosolic and C-terminal nuclear envelope lumenal domains; homologous to human NUP210","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004736","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR129W"}


id: YMR130W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04501":null,"YMR130W":null},"has_protein_features":false,"name":"DPI35","ortholog_annotations":[{"gene_uniquename":"YMR130W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04501","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR130W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04501","reference_uniquename":"PMID:26896847"}],"product":"Putative mitochondrial protein of unknown function; DPI35 is not an essential gene","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004737","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR130W"}


id: YMR131C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01122":null,"YMR131C":null},"has_protein_features":false,"name":"RRB1","ortholog_annotations":[{"gene_uniquename":"YMR131C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01122","reference_uniquename":"PMID:29761456"}],"product":"Specific assembly chaperone for ribosomal protein Rpl3p; co-translationally associates with nascent Rpl3p, preventing aggregation, and facilitating nuclear import; required for biogenesis of preribosomal particles; essential gene; contains five WD-repeat motifs","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004738","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR131C"}


id: YMR132C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01390":null,"YMR132C":null},"has_protein_features":false,"name":"JLP2","ortholog_annotations":[{"gene_uniquename":"YMR132C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01390","reference_uniquename":"PMID:26896847"}],"product":"Protein of unknown function; contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)","references_by_uniquename":{"PMID:26896847":null},"secondary_identifier":"SGD:S000004739","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR132C"}


id: YMR133W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_07002":null,"YMR133W":null},"has_protein_features":false,"name":"REC114","ortholog_annotations":[{"gene_uniquename":"YMR133W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_07002","reference_uniquename":"PMID:29761456"}],"product":"Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004740","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR133W"}


id: YMR134W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ERG29","product":"Protein of unknown function involved in ergosterol biosynthesis; conditional mutants produce less ergosterol, display impaired oxygen consumption, respiratory growth, mitochondrial iron utilization, and are more sensitive to oxidative stress; mutant bm-8 has a growth defect on iron-limited medium that is complemented by overexpression of Yfh1p; protein localizes to the cytoplasm, ER and nuclear envelope; highly conserved in ascomycetes","secondary_identifier":"SGD:S000004741","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR134W"}


id: YMR135C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01886":null,"YMR135C":null},"has_protein_features":false,"name":"GID8","ortholog_annotations":[{"gene_uniquename":"YMR135C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01886","reference_uniquename":"PMID:29761456"}],"product":"Subunit of GID Complex, binds strongly to central component Vid30p; GID Complex is involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; recruits Rmd5p, Fyv10 and Vid28p to GID Complex; contains LisH, CTLH, and CRA domains that mediate binding to Vid30p (LisH) and Rmd5p and Vid28p (CTLH and CRA); dosage-dependent regulator of START","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004742","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR135C"}


id: YMR135W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data","secondary_identifier":"SGD:S000004743","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR135W-A"}


id: YMR136W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"GAT2","product":"Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine","secondary_identifier":"SGD:S000004744","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR136W"}


id: YMR137C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03734":null,"YMR137C":null},"has_protein_features":false,"name":"PSO2","ortholog_annotations":[{"gene_uniquename":"YMR137C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03734","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR137C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03734","reference_uniquename":"PMID:26896847"}],"product":"Nuclease required for DNA single- and double-strand break repair; acts at a post-incision step in repair of breaks that result from interstrand cross-links produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation; forms nuclear foci upon DNA replication stress; translocates to mitochondria under genotoxic agents","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004745","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR137C"}


id: YMR138W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00983":null,"YMR138W":null},"has_protein_features":false,"name":"CIN4","ortholog_annotations":[{"gene_uniquename":"YMR138W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00983","reference_uniquename":"PMID:29761456"}],"product":"GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl; regulated by the GTPase-activating protein, Cin2p, the human retinitis pigmentosa 2 (RP2) homolog","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004746","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR138W"}


id: YMR139W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00718":null,"SJAG_05304":null,"YMR139W":null},"has_protein_features":false,"name":"RIM11","ortholog_annotations":[{"gene_uniquename":"YMR139W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00718","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR139W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05304","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR139W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05304","reference_uniquename":"PMID:26896847"}],"product":"Ser/Thr protein kinase; required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta; protein abundance increases in response to DNA replication stress; RIM11 has a paralog, MRK1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004747","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR139W"}


id: YMR140W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02603":null,"YMR140W":null},"has_protein_features":false,"name":"SIP5","ortholog_annotations":[{"gene_uniquename":"YMR140W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02603","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR140W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02603","reference_uniquename":"PMID:26896847"}],"product":"Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase; forms cytoplasmic foci upon DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004748","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR140W"}


id: YMR141C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; conserved among S. cerevisiae strains; YMR141C is not an essential gene","secondary_identifier":"SGD:S000004749","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR141C"}


id: YMR141W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the verified gene RPL13B/YMR142C","secondary_identifier":"SGD:S000028575","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR141W-A"}


id: YMR142C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01608":null,"SJAG_03423":null,"YMR142C":null},"has_protein_features":false,"name":"RPL13B","ortholog_annotations":[{"gene_uniquename":"YMR142C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01608","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR142C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03423","reference_uniquename":"PMID:29761456"}],"product":"Ribosomal 60S subunit protein L13B; not essential for viability; homologous to mammalian ribosomal protein L13, no bacterial homolog; RPL13B has a paralog, RPL13A, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004750","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR142C"}


id: YMR143W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01609":null,"SJAG_03422":null,"YMR143W":null},"has_protein_features":false,"name":"RPS16A","ortholog_annotations":[{"gene_uniquename":"YMR143W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01609","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR143W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01609","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR143W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03422","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR143W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03422","reference_uniquename":"PMID:29761456"}],"product":"Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S16 and bacterial S9; RPS16A has a paralog, RPS16B, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004751","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR143W"}


id: YMR144W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"FDO1","product":"Protein involved in directionality of mating type switching; acts with Fkh1p to control which donor mating-type locus is inserted into MAT locus during mating type switching; localized to the nucleus; not an essential gene","secondary_identifier":"SGD:S000004752","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR144W"}


id: YMR145C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01539":null,"YMR145C":null},"has_protein_features":false,"name":"NDE1","ortholog_annotations":[{"gene_uniquename":"YMR145C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01539","reference_uniquename":"PMID:29761456"}],"product":"Mitochondrial external NADH dehydrogenase; type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain; NDE1 has a paralog, NDE2, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004753","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR145C"}


id: YMR146C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02164":null,"YMR146C":null},"has_protein_features":false,"name":"TIF34","ortholog_annotations":[{"gene_uniquename":"YMR146C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02164","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR146C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02164","reference_uniquename":"PMID:26896847"}],"product":"eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; essential for translation; stimulates rate of ribosomal scanning during translation reinitiation; eIF3 is also involved in programmed stop codon readthrough","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004754","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR146C"}


id: YMR147W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"LDO45","product":"Putative protein of unknown function; SWAT-GFP and mCherry fusion proteins localize to the cell periphery","secondary_identifier":"SGD:S000004755","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR147W"}


id: YMR148W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"LDO16","product":"Protein of unknown function with possible role in spore wall assembly; predicted to contain an N-terminal transmembrane domain; osw5 null mutant spores exhibit increased spore wall permeability and sensitivity to beta-glucanase digestion","secondary_identifier":"SGD:S000004756","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR148W"}


id: YMR149W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04090":null,"YMR149W":null},"has_protein_features":false,"name":"SWP1","ortholog_annotations":[{"gene_uniquename":"YMR149W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04090","reference_uniquename":"PMID:29761456"}],"product":"Delta subunit of the oligosaccharyl transferase glycoprotein complex; complex is required for N-linked glycosylation of proteins in the endoplasmic reticulum","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004757","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR149W"}


id: YMR150C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03648":null,"YMR150C":null},"has_protein_features":false,"name":"IMP1","ortholog_annotations":[{"gene_uniquename":"YMR150C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03648","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR150C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03648","reference_uniquename":"PMID:26896847"}],"product":"Catalytic subunit of mitochondrial inner membrane peptidase complex; required for maturation of mitochondrial proteins of the intermembrane space; complex contains two catalytic subunits (Imp1p and Imp2p that differ in substrate specificty) and Som1p","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004758","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR150C"}


id: YMR151W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"YIM2","product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 5% of ORF overlaps the verified gene IMP1","secondary_identifier":"SGD:S000004759","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR151W"}


id: YMR152W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04376":null,"YMR152W":null},"has_protein_features":false,"name":"YIM1","ortholog_annotations":[{"gene_uniquename":"YMR152W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04376","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR152W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04376","reference_uniquename":"PMID:26896847"}],"product":"Aldehyde reductase; involved in detoxification of lignocellulose-derived aldehydes; catalyzes the reduction of furan, aliphatic and aromatic aldehydes using either NADH or NADPH as co-factor; membrane of the quinone oxidoreductase subfamily of the medium-chain dehydrogenase/reductase family; null mutant displays sensitivity to DNA damaging agents; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004760","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR152W"}


id: YMR153C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps 3' end of verified gene NUP53/YMR153W","secondary_identifier":"SGD:S000004761","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR153C-A"}


id: YMR153W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03593":null,"YMR153W":null},"has_protein_features":false,"name":"NUP53","ortholog_annotations":[{"gene_uniquename":"YMR153W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03593","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR153W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03593","reference_uniquename":"PMID:26896847"}],"product":"FG-nucleoporin component of central core of nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes directly to nucleocytoplasmic transport; involved in regulation of transcription and mitosis; induces membrane tubulation, which may contribute to nuclear pore assembly; NUP53 has a paralog, ASM4, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004762","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR153W"}


id: YMR154C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RIM13","product":"Calpain-like cysteine protease; involved in proteolytic activation of Rim101p in response to alkaline pH; localizes to punctate structures in alkaline conditions and in vps4 mutant; has similarity to A. nidulans palB","secondary_identifier":"SGD:S000004763","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR154C"}


id: YMR155W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen","secondary_identifier":"SGD:S000004764","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR155W"}


id: YMR156C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02680":null,"YMR156C":null},"has_protein_features":false,"name":"TPP1","ortholog_annotations":[{"gene_uniquename":"YMR156C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02680","reference_uniquename":"PMID:29761456"}],"product":"DNA 3'-phosphatase; functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; similar to the l-2-haloacid dehalogenase superfamily; homolog of human polynucleotide kinase/3'-phosphatase","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004765","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR156C"}


id: YMR157C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"AIM36","product":"Protein of unknown function; null mutant displays reduced respiratory growth and elevated frequency of mitochondrial genome loss; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies","secondary_identifier":"SGD:S000004766","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR157C"}


id: YMR158C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; may contain a lipid attachment site; localizes to cytosol, and to peroxisomes in oleate-growing cells; YMR158C-A is not an essential gene","secondary_identifier":"SGD:S000007249","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR158C-A"}


id: YMR158W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05320":null,"YMR158W":null},"has_protein_features":false,"name":"MRPS8","ortholog_annotations":[{"gene_uniquename":"YMR158W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05320","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR158W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05320","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial ribosomal protein of the small subunit","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004767","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR158W"}


id: YMR158W-B
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the verified gene ATG16/YMR159C","secondary_identifier":"SGD:S000004768","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR158W-B"}


id: YMR159C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03136":null,"YMR159C":null},"has_protein_features":false,"name":"ATG16","ortholog_annotations":[{"gene_uniquename":"YMR159C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03136","reference_uniquename":"PMID:29761456"}],"product":"Conserved protein involved in autophagy; interacts with Atg12p-Atg5p conjugates to form Atg12p-Atg5p-Atg16p multimers, which binds to membranes and localizes to the pre-autophagosomal structure and are required for autophagy; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004769","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR159C"}


id: YMR160W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"CVM1","product":"Protein involved in sphingolipid metabolism; localizes to vacuolar contact sites with mitochondria, ER and peroxisomes; mutant has enhanced sensitivity to overexpression of mutant huntingtin; relative distribution within the vacuolar membrane changes upon DNA replication stress","secondary_identifier":"SGD:S000004770","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR160W"}


id: YMR161W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01160":null,"YMR161W":null},"has_protein_features":false,"name":"HLJ1","ortholog_annotations":[{"gene_uniquename":"YMR161W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01160","reference_uniquename":"PMID:26896847"}],"product":"Co-chaperone for Hsp40p; anchored in the ER membrane; with its homolog Ydj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ","references_by_uniquename":{"PMID:26896847":null},"secondary_identifier":"SGD:S000004771","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR161W"}


id: YMR162C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00669":null,"YMR162C":null},"has_protein_features":false,"name":"DNF3","ortholog_annotations":[{"gene_uniquename":"YMR162C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00669","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR162C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00669","reference_uniquename":"PMID:26896847"}],"product":"Trans-golgi network aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to the maintenance of membrane lipid asymmetry in post-Golgi secretory vesicles; role in protein trafficking between the Golgi and endosomal system; localizes to the trans-Golgi network; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004772","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR162C"}


id: YMR163C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04315":null,"YMR163C":null},"has_protein_features":false,"name":"INP2","ortholog_annotations":[{"gene_uniquename":"YMR163C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04315","reference_uniquename":"PMID:29761456"}],"product":"Peroxisome-specific receptor important for peroxisome inheritance; co-fractionates with peroxisome membranes and co-localizes with peroxisomes in vivo; physically interacts with the myosin V motor Myo2p; INP2 is not an essential gene","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004773","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR163C"}


id: YMR164C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"MSS11","product":"Transcription factor; involved in regulation of invasive growth and starch degradation; controls the activation of FLO11 and STA2 in response to nutritional signals; forms a heterodimer with Flo8p that interacts with the Swi/Snf complex during transcriptional activation of FLO1, FLO11, and STA1","secondary_identifier":"SGD:S000004774","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR164C"}


id: YMR165C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02763":null,"YMR165C":null},"has_protein_features":false,"name":"PAH1","ortholog_annotations":[{"gene_uniquename":"YMR165C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02763","reference_uniquename":"PMID:29761456"}],"product":"Mg2+-dependent phosphatidate (PA) phosphatase; dephosphorylates PA to yield diacylglycerol; regulates phospholipid synthesis, nuclear/ER membrane growth, lipid droplet formation, triacylglycerol synthesis, vacuolar homeostasis and cell wall integrity; phosphorylated by Pho85p/Pho80p, Cdc28p/Cyclin B, PKA, PKC, and CKII, regulating activity, localization, and proteosomal degradation; homolog of mammalian lipins 1 and 2; human homologs LPIN1, LPIN2, LPIN3 complement the null","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004775","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR165C"}


id: YMR166C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02484":null,"YMR166C":null},"has_protein_features":false,"name":"MME1","ortholog_annotations":[{"gene_uniquename":"YMR166C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02484","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR166C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02484","reference_uniquename":"PMID:26896847"}],"product":"Transporter of the mitochondrial inner membrane that exports magnesium; involved in mitochondrial Mg2+ homeostasis; has similarity to human mitochondrial ATP-Mg/Pi carriers","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004776","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR166C"}


id: YMR167W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01620":null,"YMR167W":null},"has_protein_features":false,"name":"MLH1","ortholog_annotations":[{"gene_uniquename":"YMR167W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01620","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR167W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01620","reference_uniquename":"PMID:26896847"}],"product":"Protein required for mismatch repair in mitosis and meiosis; also required for crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; required for silencing at the silent mating-type loci and telomeres; human homolog is associated with hereditary non-polyposis colon cancer","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004777","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR167W"}


id: YMR168C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"CEP3","product":"Essential kinetochore protein; component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain","secondary_identifier":"SGD:S000004778","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR168C"}


id: YMR169C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ALD3","product":"Cytoplasmic aldehyde dehydrogenase; involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose","secondary_identifier":"SGD:S000004779","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR169C"}


id: YMR170C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ALD2","product":"Cytoplasmic aldehyde dehydrogenase; involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p","secondary_identifier":"SGD:S000004780","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR170C"}


id: YMR171C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01586":null,"YMR171C":null},"has_protein_features":false,"name":"EAR1","ortholog_annotations":[{"gene_uniquename":"YMR171C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01586","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR171C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01586","reference_uniquename":"PMID:26896847"}],"product":"Specificity factor required for Rsp5p-dependent ubiquitination; also required for sorting of specific cargo proteins at the multivesicular body; mRNA is targeted to the bud via the mRNA transport system involving She2p","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004781","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR171C"}


id: YMR172C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps 3' end of ORF HOT1/YMR172W","secondary_identifier":"SGD:S000004782","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR172C-A"}


id: YMR172W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"HOT1","product":"Transcription factor for glycerol biosynthetic genes; required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p","secondary_identifier":"SGD:S000004783","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR172W"}


id: YMR173W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02442":null,"YMR173W":null},"has_protein_features":false,"name":"DDR48","ortholog_annotations":[{"gene_uniquename":"YMR173W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02442","reference_uniquename":"PMID:29761456"}],"product":"DNA damage-responsive protein; expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004784","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR173W"}


id: YMR173W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the verified gene DDR48/YML173W","secondary_identifier":"SGD:S000004785","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR173W-A"}


id: YMR174C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"PAI3","product":"Cytoplasmic proteinase A (Pep4p) inhibitor; dependent on Pbs2p and Hog1p protein kinases for osmotic induction; intrinsically unstructured, N-terminal half becomes ordered in the active site of proteinase A upon contact","secondary_identifier":"SGD:S000004786","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR174C"}


id: YMR175W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SIP18","product":"Phospholipid-binding hydrophilin; essential to overcome desiccation-rehydration process; expression is induced by osmotic stress; SIP18 has a paralog, GRE1, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004787","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR175W"}


id: YMR175W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function","secondary_identifier":"SGD:S000028848","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR175W-A"}


id: YMR176W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01465":null,"SJAG_03635":null,"YMR176W":null},"has_protein_features":false,"name":"ECM5","ortholog_annotations":[{"gene_uniquename":"YMR176W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01465","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR176W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03635","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR176W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03635","reference_uniquename":"PMID:26896847"}],"product":"Subunit of the Snt2C complex; physically associates with Snt2p and Rpd3p; along with Snt2p, recruits Rpd3p to a small number of promoters; also colocalizes with Snt2p, independently of Rpd3p, to promoters of stress response genes in response to oxidative stress; contains ATP/GTP-binding site motif A; null mutant exhibits increased cellular volume, large drooping buds with elongated necks; relative distribution to the nucleus increases upon DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004788","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR176W"}


id: YMR177W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04260":null,"YMR177W":null},"has_protein_features":false,"name":"MMT1","ortholog_annotations":[{"gene_uniquename":"YMR177W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04260","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR177W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04260","reference_uniquename":"PMID:26896847"}],"product":"Putative metal transporter involved in mitochondrial iron accumulation; MMT1 has a paralog, MMT2, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004789","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR177W"}


id: YMR178W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"FPY1","product":"FAD pyrophosphatase; hydrolyzes FAD as the preferred substrate but also acts on NADH and ADP-ribose at lower rates; activity is dependent upon K+ and divalent metal cations; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus; FPY1 is not an essential gene; protein abundance increases in response to DNA replication stress","secondary_identifier":"SGD:S000004790","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR178W"}


id: YMR179W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03183":null,"YMR179W":null},"has_protein_features":false,"name":"SPT21","ortholog_annotations":[{"gene_uniquename":"YMR179W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03183","reference_uniquename":"PMID:29761456"}],"product":"Protein with a role in transcriptional silencing; required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; binds with Spt10p to histone gene promoters during S phase; localizes to nuclear foci that become diffuse upon DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004791","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR179W"}


id: YMR180C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04488":null,"YMR180C":null},"has_protein_features":false,"name":"CTL1","ortholog_annotations":[{"gene_uniquename":"YMR180C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04488","reference_uniquename":"PMID:29761456"}],"product":"RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm; CTL1 has a paralog, CET1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004792","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR180C"}


id: YMR181C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; mRNA transcribed as part of a bicistronic transcript with a predicted transcriptional repressor RGM1/YMR182C; mRNA is destroyed by nonsense-mediated decay (NMD); not an essential gene; YMR181C has a paralog, YPL229W, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004793","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR181C"}


id: YMR182C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RGM1","product":"Putative zinc finger DNA binding transcription factor; contains two N-terminal C2H2 zinc fingers and C-terminal proline rich domain; overproduction impairs cell growth and induces expression of genes involved in monosaccharide catabolism and aldehyde metabolism; regulates expression of of Y' telomeric elements and subtelomeric COS genes; relocalizes to the cytosol in response to hypoxia; RGM1 has a paralog, USV1, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004794","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR182C"}


id: YMR182W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"MIN3","product":"Mitochondrial protein of unknown function","secondary_identifier":"SGD:S000028693","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR182W-A"}


id: YMR183C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03536":null,"YMR183C":null},"has_protein_features":false,"name":"SSO2","ortholog_annotations":[{"gene_uniquename":"YMR183C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03536","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR183C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03536","reference_uniquename":"PMID:26896847"}],"product":"Plasma membrane t-SNARE; involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p; SSO2 has a paralog, SSO1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004795","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR183C"}


id: YMR184W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ADD37","product":"Protein of unknown function; involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene; protein abundance increases in response to DNA replication stress","secondary_identifier":"SGD:S000004796","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR184W"}


id: YMR185W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01328":null,"YMR185W":null},"has_protein_features":false,"name":"RTP1","ortholog_annotations":[{"gene_uniquename":"YMR185W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01328","reference_uniquename":"PMID:29761456"}],"product":"Protein required for the nuclear import and biogenesis of RNA pol II; conflicting evidence on whether null mutant is viable with elongated buds, or inviable; interacts with Rpb2, Rpb3, Nup116p, Nup100p and components of the R2TP complex (Rvb1p, Rvb2p, Pih1p); similar to human TMCO7 gene","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004797","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR185W"}


id: YMR186W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01664":null,"YMR186W":null},"has_protein_features":false,"name":"HSC82","ortholog_annotations":[{"gene_uniquename":"YMR186W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01664","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR186W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01664","reference_uniquename":"PMID:26896847"}],"product":"Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004798","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR186W"}


id: YMR187C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01212":null,"YMR187C":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YMR187C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01212","reference_uniquename":"PMID:29761456"}],"product":"Putative protein of unknown function; YMR187C is not an essential gene","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004799","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR187C"}


id: YMR188C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02359":null,"YMR188C":null},"has_protein_features":false,"name":"MRPS17","ortholog_annotations":[{"gene_uniquename":"YMR188C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02359","reference_uniquename":"PMID:29761456"}],"product":"Mitochondrial ribosomal protein of the small subunit","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004800","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR188C"}


id: YMR189W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03861":null,"YMR189W":null},"has_protein_features":false,"name":"GCV2","ortholog_annotations":[{"gene_uniquename":"YMR189W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03861","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR189W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03861","reference_uniquename":"PMID:26896847"}],"product":"P subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004801","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR189W"}


id: YMR190C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03898":null,"YMR190C":null},"has_protein_features":false,"name":"SGS1","ortholog_annotations":[{"gene_uniquename":"YMR190C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03898","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR190C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03898","reference_uniquename":"PMID:26896847"}],"product":"RecQ family nucleolar DNA helicase; role in genome integrity maintenance, chromosome synapsis, meiotic joint molecule/crossover formation; stimulates activity of Top3p; rapidly lost in response to rapamycin in Rrd1p-dependent manner; forms nuclear foci upon DNA replication stress; yeast SGS1 complements mutations in human homolog BLM implicated in Bloom syndrome; also similar to human WRN implicated in Werner syndrome; human BLM and WRN can each complement yeast null mutant","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004802","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR190C"}


id: YMR191W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SPG5","product":"Protein required for proteasome assembly during quiescence; binds to base of the proteasome regulartory particle; required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources","secondary_identifier":"SGD:S000004803","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR191W"}


id: YMR192W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00092":null,"SJAG_02012":null,"YMR192W":null},"has_protein_features":false,"name":"GYL1","ortholog_annotations":[{"gene_uniquename":"YMR192W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00092","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR192W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02012","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR192W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02012","reference_uniquename":"PMID:26896847"}],"product":"Putative GTPase activating protein (GAP) with a role in exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; increases in abundance and relocalizes from bud neck to cytoplasm upon DNA replication stress; GYL1 has a paralog, GYP5, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004804","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR192W"}


id: YMR193C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data","secondary_identifier":"SGD:S000004805","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR193C-A"}


id: YMR193W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02071":null,"YMR193W":null},"has_protein_features":false,"name":"MRPL24","ortholog_annotations":[{"gene_uniquename":"YMR193W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02071","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR193W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02071","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial ribosomal protein of the large subunit; two mitochondrial ribosomal proteins, YmL14 and YmL24, have been assigned to the same gene","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004806","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR193W"}


id: YMR194C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data","secondary_identifier":"SGD:S000007250","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR194C-A"}


id: YMR194C-B
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"CMC4","product":"Protein that localizes to the mitochondrial intermembrane space; localizes via the Mia40p-Erv1p system; contains twin cysteine-x(9)-cysteine motifs","secondary_identifier":"SGD:S000028514","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR194C-B"}


id: YMR194W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02121":null,"SJAG_03133":null,"YMR194W":null},"has_protein_features":false,"name":"RPL36A","ortholog_annotations":[{"gene_uniquename":"YMR194W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02121","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR194W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02121","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR194W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03133","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR194W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03133","reference_uniquename":"PMID:29761456"}],"product":"Ribosomal 60S subunit protein L36A; N-terminally acetylated; binds to 5.8 S rRNA; homologous to mammalian ribosomal protein L36, no bacterial homolog; RPL36A has a paralog, RPL36B, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004807","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR194W"}


id: YMR195W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ICY1","product":"Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ATG41, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004808","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR195W"}


id: YMR196W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR196W is not an essential gene","secondary_identifier":"SGD:S000004809","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR196W"}


id: YMR197C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04023":null,"YMR197C":null},"has_protein_features":false,"name":"VTI1","ortholog_annotations":[{"gene_uniquename":"YMR197C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04023","reference_uniquename":"PMID:29761456"}],"product":"Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways; human homolog VTI1A can complement yeast null mutant","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004810","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR197C"}


id: YMR198W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"CIK1","product":"Kinesin-associated protein; required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; locus encodes a long and short transcript with differing functions; CIK1 has a paralog, VIK1, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004811","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR198W"}


id: YMR199W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"CLN1","product":"G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p); CLN1 has a paralog, CLN2, that arose from the whole genome duplication; cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1","secondary_identifier":"SGD:S000004812","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR199W"}


id: YMR200W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05189":null,"YMR200W":null},"has_protein_features":false,"name":"ROT1","ortholog_annotations":[{"gene_uniquename":"YMR200W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05189","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR200W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05189","reference_uniquename":"PMID:26896847"}],"product":"Molecular chaperone involved in protein folding in ER; mutation causes defects in cell wall synthesis and lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations; involved in N-linked glycosylation and O-mannosylation; transmembrane helix Ser250 is essential for Rot1p to interact with other membrane components and exert its functional role, avoiding exposure of Ser H-bonding group at lipid-exposed surface","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004813","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR200W"}


id: YMR201C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02334":null,"YMR201C":null},"has_protein_features":false,"name":"RAD14","ortholog_annotations":[{"gene_uniquename":"YMR201C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02334","reference_uniquename":"PMID:29761456"}],"product":"Subunit of Nucleotide Excision Repair Factor 1 (NEF1); recognizes and binds damaged DNA during nucleotide excision repair (NER); also involved in regulation of transcription; contains zinc finger motif; homolog of human XPA protein","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004814","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR201C"}


id: YMR202W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03598":null,"YMR202W":null},"has_protein_features":false,"name":"ERG2","ortholog_annotations":[{"gene_uniquename":"YMR202W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03598","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR202W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03598","reference_uniquename":"PMID:26896847"}],"product":"C-8 sterol isomerase; catalyzes isomerization of delta-8 double bond to delta-7 position at an intermediate step in ergosterol biosynthesis; transcriptionally down-regulated when ergosterol is in excess; mutation is functionally complemented by human EBP","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004815","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR202W"}


id: YMR203W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03515":null,"YMR203W":null},"has_protein_features":false,"name":"TOM40","ortholog_annotations":[{"gene_uniquename":"YMR203W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03515","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR203W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03515","reference_uniquename":"PMID:26896847"}],"product":"Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore; pre-Tom40p is phosphorylated by PKA, which impairs its import into mitochondria under non-respiratory conditions","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004816","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR203W"}


id: YMR204C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"INP1","product":"Peripheral membrane protein of peroxisomes; involved in peroxisomal inheritance; recruitment to peroxisomes is mediated by interaction with Pex3p at the peroxisomal membrane; Inp1p and Pex3p tether peroxisomes to plasma membrane","secondary_identifier":"SGD:S000004817","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR204C"}


id: YMR205C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00605":null,"YMR205C":null},"has_protein_features":false,"name":"PFK2","ortholog_annotations":[{"gene_uniquename":"YMR205C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00605","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR205C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00605","reference_uniquename":"PMID:26896847"}],"product":"Beta subunit of heterooctameric phosphofructokinase; involved in glycolysis; indispensable for anaerobic growth; activated by fructose-2,6-bisphosphate and AMP; mutation inhibits glucose induction of cell cycle-related genes","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004818","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR205C"}


id: YMR206W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; not an essential gene; YMR206W has a paralog, YNR014W, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004819","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR206W"}


id: YMR207C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03313":null,"YMR207C":null},"has_protein_features":false,"name":"HFA1","ortholog_annotations":[{"gene_uniquename":"YMR207C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03313","reference_uniquename":"PMID:29761456"}],"product":"Mitochondrial acetyl-coenzyme A carboxylase; catalyzes production of malonyl-CoA in mitochondrial fatty acid biosynthesis; relocalizes from mitochondrion to cytoplasm upon DNA replication stress; genetic and comparative analysis suggests that translation begins at a non-canonical (Ile) start codon at -372 relative to the annotated start codon","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004820","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR207C"}


id: YMR208W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04865":null,"YMR208W":null},"has_protein_features":false,"name":"ERG12","ortholog_annotations":[{"gene_uniquename":"YMR208W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04865","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR208W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04865","reference_uniquename":"PMID:26896847"}],"product":"Mevalonate kinase; acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate; human MVK functionally complements the lethality of the erg12 null mutation","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004821","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR208W"}


id: YMR209C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03087":null,"YMR209C":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YMR209C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03087","reference_uniquename":"PMID:29761456"}],"product":"Putative S-adenosylmethionine-dependent methyltransferase; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; YMR209C is not an essential gene","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004822","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR209C"}


id: YMR210W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"MGL2","product":"Monoacylglycerol and triacylglycerol lipase; MAG lipase with preference for palmitoyl-MAG; TAG lipase involved in TAG catabolism; minor role in medium-chain fatty acid ethyl ester biosynthesis; contains an alpha/beta hydrolase domain and a typical lipase motif (GXSXG); similar to acyltransferases, Eeb1p, Eht1p, and human ABHD1","secondary_identifier":"SGD:S000004823","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR210W"}


id: YMR211W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02265":null,"YMR211W":null},"has_protein_features":false,"name":"DML1","ortholog_annotations":[{"gene_uniquename":"YMR211W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02265","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR211W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02265","reference_uniquename":"PMID:26896847"}],"product":"Essential protein involved in mtDNA inheritance; may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004824","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR211W"}


id: YMR212C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04158":null,"SJAG_04930":null,"YMR212C":null},"has_protein_features":false,"name":"EFR3","ortholog_annotations":[{"gene_uniquename":"YMR212C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04158","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR212C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04930","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR212C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04930","reference_uniquename":"PMID:26896847"}],"product":"Protein required for Stt4-containing PI kinase complex localization; required for Stt4-containing phosphoinositide (PI) kinase patch assembly at plasma membrane; recruited to plasma membrane via conserved basic patch near N-terminus; exhibits synthetic lethal genetic interactions with PHO85; mutations in human homolog EFR3A implicated in autism spectrum disorders","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004825","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR212C"}


id: YMR213W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01408":null,"YMR213W":null},"has_protein_features":false,"name":"CEF1","ortholog_annotations":[{"gene_uniquename":"YMR213W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01408","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR213W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01408","reference_uniquename":"PMID:26896847"}],"product":"Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004826","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR213W"}


id: YMR214W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00403":null,"YMR214W":null},"has_protein_features":false,"name":"SCJ1","ortholog_annotations":[{"gene_uniquename":"YMR214W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00403","reference_uniquename":"PMID:29761456"}],"product":"One of several homologs of bacterial chaperone DnaJ; located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004827","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR214W"}


id: YMR215W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01835":null,"YMR215W":null},"has_protein_features":false,"name":"GAS3","ortholog_annotations":[{"gene_uniquename":"YMR215W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01835","reference_uniquename":"PMID:26896847"}],"product":"Putative 1,3-beta-glucanosyltransferase; has similarity go other GAS family members; low abundance, possibly inactive member of the GAS family of GPI-containing proteins; localizes to the cell wall; mRNA induced during sporulation","references_by_uniquename":{"PMID:26896847":null},"secondary_identifier":"SGD:S000004828","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR215W"}


id: YMR216C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02058":null,"SJAG_05231":null,"YMR216C":null},"has_protein_features":false,"name":"SKY1","ortholog_annotations":[{"gene_uniquename":"YMR216C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02058","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR216C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05231","reference_uniquename":"PMID:26896847"}],"product":"SR protein kinase (SRPK); involved in mRNA 3' splice site recognition with Prp8p and Cdc40p; phosphorylates one or more SR dipeptides on mRNA export factors Npl3p and Gbp2p to stimulate cytoplasmic release of mRNA and Mtr10p-mediated nuclear reimport; component of stress granules that regulates granule disassembly during recovery from stress; modulates cation uptake and homeostasis through membrane transporters; contains prion-like domains; similar to human SRPK1","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004829","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR216C"}


id: YMR217W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04634":null,"YMR217W":null},"has_protein_features":false,"name":"GUA1","ortholog_annotations":[{"gene_uniquename":"YMR217W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04634","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR217W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04634","reference_uniquename":"PMID:26896847"}],"product":"GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004830","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR217W"}


id: YMR218C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02750":null,"YMR218C":null},"has_protein_features":false,"name":"TRS130","ortholog_annotations":[{"gene_uniquename":"YMR218C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02750","reference_uniquename":"PMID:29761456"}],"product":"Component of transport protein particle (TRAPP) complex II; TRAPPII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating intra-Golgi and endosome-Golgi traffic","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004831","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR218C"}


id: YMR219W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ESC1","product":"Protein involved in telomeric silencing; required for quiescent cell telomere hypercluster localization at nuclear membrane vicinity; interacts with PAD4-domain of Sir4p","secondary_identifier":"SGD:S000004832","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR219W"}


id: YMR220W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01474":null,"YMR220W":null},"has_protein_features":false,"name":"ERG8","ortholog_annotations":[{"gene_uniquename":"YMR220W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01474","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR220W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01474","reference_uniquename":"PMID:26896847"}],"product":"Phosphomevalonate kinase; an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004833","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR220W"}


id: YMR221C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"FMP42","product":"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy; targeted to vacuole via AP-3 pathway","secondary_identifier":"SGD:S000004834","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR221C"}


id: YMR222C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03760":null,"YMR222C":null},"has_protein_features":false,"name":"FSH2","ortholog_annotations":[{"gene_uniquename":"YMR222C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03760","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR222C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03760","reference_uniquename":"PMID:26896847"}],"product":"Putative serine hydrolase that localizes to the cytoplasm; sequence is similar to S. cerevisiae Fsh1p and Fsh3p and the human candidate tumor suppressor OVCA2","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004835","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR222C"}


id: YMR223W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03752":null,"YMR223W":null},"has_protein_features":false,"name":"UBP8","ortholog_annotations":[{"gene_uniquename":"YMR223W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03752","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR223W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03752","reference_uniquename":"PMID:26896847"}],"product":"Ubiquitin-specific protease component of the SAGA acetylation complex; required for SAGA (Spt-Ada-Gcn5-Acetyltransferase)-mediated deubiquitination of histone H2B","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004836","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR223W"}


id: YMR224C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05373":null,"YMR224C":null},"has_protein_features":false,"name":"MRE11","ortholog_annotations":[{"gene_uniquename":"YMR224C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05373","reference_uniquename":"PMID:29761456"}],"product":"Nuclease subunit of the MRX complex with Rad50p and Xrs2p; complex functions in repair of DNA double-strand breaks and in telomere stability; Mre11p associates with Ser/Thr-rich ORFs in premeiotic phase; nuclease activity required for MRX function; widely conserved; forms nuclear foci upon DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004837","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR224C"}


id: YMR225C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_06110":null,"YMR225C":null},"has_protein_features":false,"name":"MRPL44","ortholog_annotations":[{"gene_uniquename":"YMR225C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06110","reference_uniquename":"PMID:29761456"}],"product":"Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004838","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR225C"}


id: YMR226C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01492":null,"SJAG_01690":null,"SJAG_01850":null,"SJAG_03492":null,"SJAG_04027":null,"YMR226C":null},"has_protein_features":false,"name":"ORA1","ortholog_annotations":[{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01492","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01492","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01690","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01690","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01850","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01850","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03492","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03492","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04027","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR226C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04027","reference_uniquename":"PMID:26896847"}],"product":"NADP(+)-dependent serine dehydrogenase and carbonyl reductase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; catalyzes the reduction of (S)-α-acetolactate to 2,3-dimethylglycerate; short-chain dehydrogenase/reductase (SDR) family member; GFP fusion protein localizes to the cytoplasm and nucleus","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004839","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR226C"}


id: YMR227C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01808":null,"YMR227C":null},"has_protein_features":false,"name":"TAF7","ortholog_annotations":[{"gene_uniquename":"YMR227C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01808","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR227C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01808","reference_uniquename":"PMID:26896847"}],"product":"TFIID subunit (67 kDa); involved in RNA polymerase II transcription initiation","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004840","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR227C"}


id: YMR228W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03289":null,"YMR228W":null},"has_protein_features":false,"name":"MTF1","ortholog_annotations":[{"gene_uniquename":"YMR228W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03289","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR228W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03289","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004841","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR228W"}


id: YMR229C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02530":null,"YMR229C":null},"has_protein_features":false,"name":"RRP5","ortholog_annotations":[{"gene_uniquename":"YMR229C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02530","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR229C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02530","reference_uniquename":"PMID:26896847"}],"product":"RNA binding protein involved in synthesis of 18S and 5.8S rRNAs; component of ribosomal small subunit (SSU) processome and 90S preribosome; required for pre-rRNA packaging and compaction of processome into dense terminal balls; part of Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription with role in biogenesis of large ribosomal subunit; binds single stranded tracts of U's; relocalizes from nucleolus to nucleus upon DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004842","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR229C"}


id: YMR230W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02904":null,"SJAG_04695":null,"YMR230W":null},"has_protein_features":false,"name":"RPS10B","ortholog_annotations":[{"gene_uniquename":"YMR230W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02904","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR230W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02904","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR230W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04695","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR230W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04695","reference_uniquename":"PMID:29761456"}],"product":"Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10B has a paralog, RPS10A, that arose from the whole genome duplication; mutations in the human homolog associated with Diamond-Blackfan anemia","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004843","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR230W"}


id: YMR230W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function","secondary_identifier":"SGD:S000028576","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR230W-A"}


id: YMR231W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01772":null,"SJAG_04966":null,"YMR231W":null},"has_protein_features":false,"name":"PEP5","ortholog_annotations":[{"gene_uniquename":"YMR231W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01772","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR231W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01772","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR231W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04966","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR231W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04966","reference_uniquename":"PMID:26896847"}],"product":"Histone E3 ligase, component of CORVET membrane tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p; involved in ubiquitination and degradation of excess histones","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004844","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR231W"}


id: YMR232W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02645":null,"SJAG_03581":null,"YMR232W":null},"has_protein_features":false,"name":"FUS2","ortholog_annotations":[{"gene_uniquename":"YMR232W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02645","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR232W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03581","reference_uniquename":"PMID:29761456"}],"product":"Cell fusion regulator; cytoplasmic protein localized to shmoo tip; required for alignment of parental nuclei before nuclear fusion during mating; contains a Dbl-homology domain; binds specifically with activated Cdc42p","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004845","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR232W"}


id: YMR233W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02747":null,"YMR233W":null},"has_protein_features":false,"name":"TRI1","ortholog_annotations":[{"gene_uniquename":"YMR233W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02747","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR233W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02747","reference_uniquename":"PMID:26896847"}],"product":"Non-essential sumoylated protein of unknown function; similar to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus; TRI1 has a paralog, UAF30, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004846","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR233W"}


id: YMR234W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_06022":null,"YMR234W":null},"has_protein_features":false,"name":"RNH1","ortholog_annotations":[{"gene_uniquename":"YMR234W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06022","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR234W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06022","reference_uniquename":"PMID:26896847"}],"product":"Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I.","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004847","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR234W"}


id: YMR235C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04400":null,"YMR235C":null},"has_protein_features":false,"name":"RNA1","ortholog_annotations":[{"gene_uniquename":"YMR235C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04400","reference_uniquename":"PMID:29761456"}],"product":"GTPase activating protein (GAP) for Gsp1p; involved in nuclear transport","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004848","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR235C"}


id: YMR236W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01475":null,"YMR236W":null},"has_protein_features":false,"name":"TAF9","ortholog_annotations":[{"gene_uniquename":"YMR236W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01475","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR236W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01475","reference_uniquename":"PMID:26896847"}],"product":"Subunit (17 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004849","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR236W"}


id: YMR237W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00916":null,"YMR237W":null},"has_protein_features":false,"name":"BCH1","ortholog_annotations":[{"gene_uniquename":"YMR237W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00916","reference_uniquename":"PMID:29761456"}],"product":"Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins from the Golgi to the plasma membrane; interacts selectively with the activated, GTP-bound form of Arf1p; may interact with ribosomes; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004850","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR237W"}


id: YMR238W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00310":null,"SJAG_04850":null,"SJAG_04851":null,"SJAG_05272":null,"YMR238W":null},"has_protein_features":false,"name":"DFG5","ortholog_annotations":[{"gene_uniquename":"YMR238W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00310","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR238W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00310","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR238W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04850","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR238W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04850","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR238W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04851","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR238W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04851","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR238W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05272","reference_uniquename":"PMID:26896847"}],"product":"Putative mannosidase; essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004851","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR238W"}


id: YMR239C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02156":null,"SJAG_04527":null,"YMR239C":null},"has_protein_features":false,"name":"RNT1","ortholog_annotations":[{"gene_uniquename":"YMR239C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02156","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR239C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04527","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR239C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04527","reference_uniquename":"PMID:26896847"}],"product":"Nuclear dsRNA-specific ribonuclease (RNase III); involved in rDNA transcription, rRNA processing and U2 snRNA 3' end formation by cleavage of a stem-loop structure at the 3' end of U2 snRNA; involved in polyadenylation-independent transcription termination; involved in the cell wall stress response, regulating the degradation of cell wall integrity and morphogenesis checkpoint genes","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004852","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR239C"}


id: YMR240C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00322":null,"YMR240C":null},"has_protein_features":false,"name":"CUS1","ortholog_annotations":[{"gene_uniquename":"YMR240C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00322","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR240C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00322","reference_uniquename":"PMID:26896847"}],"product":"Protein required for assembly of U2 snRNP into the spliceosome; forms a complex with Hsh49p and Hsh155p","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004853","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR240C"}


id: YMR241W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00275":null,"YMR241W":null},"has_protein_features":false,"name":"YHM2","ortholog_annotations":[{"gene_uniquename":"YMR241W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00275","reference_uniquename":"PMID:29761456"}],"product":"Citrate and oxoglutarate carrier protein; exports citrate from and imports oxoglutarate into the mitochondrion, causing net export of NADPH reducing equivalents; also associates with mt nucleoids and has a role in replication and segregation of the mt genome","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004854","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR241W"}


id: YMR242C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02283":null,"SJAG_04897":null,"YMR242C":null},"has_protein_features":false,"name":"RPL20A","ortholog_annotations":[{"gene_uniquename":"YMR242C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02283","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR242C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02283","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR242C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04897","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR242C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04897","reference_uniquename":"PMID:29761456"}],"product":"Ribosomal 60S subunit protein L20A; homologous to mammalian ribosomal protein L18A, no bacterial homolog; RPL20A has a paralog, RPL20B, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004855","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR242C"}


id: YMR242W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function","secondary_identifier":"SGD:S000028694","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR242W-A"}


id: YMR243C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01078":null,"SJAG_01803":null,"YMR243C":null},"has_protein_features":false,"name":"ZRC1","ortholog_annotations":[{"gene_uniquename":"YMR243C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01078","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR243C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01078","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR243C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01803","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR243C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01803","reference_uniquename":"PMID:26896847"}],"product":"Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004856","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR243C"}


id: YMR244C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02229":null,"YMR244C-A":null},"has_protein_features":false,"name":"COA6","ortholog_annotations":[{"gene_uniquename":"YMR244C-A","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02229","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR244C-A","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02229","reference_uniquename":"PMID:26896847"}],"product":"Protein involved in cytochrome c oxidase (Complex IV) assembly; involved in delivery of copper to Complex IV; also required for efficient formation of respiratory supercomplexes comprised of Complexes III and IV; localizes to the mitochondrial intermembrane space; ortholog implicated in cardiac defects in zebrafish and human; transcription is induced in response to the DNA-damaging agent MMS; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004857","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR244C-A"}


id: YMR244W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02478":null,"YMR244W":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YMR244W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02478","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR244W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02478","reference_uniquename":"PMID:26896847"}],"product":"Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004858","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR244W"}


id: YMR245W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data","secondary_identifier":"SGD:S000004859","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR245W"}


id: YMR246W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03471":null,"SJAG_03909":null,"YMR246W":null},"has_protein_features":false,"name":"FAA4","ortholog_annotations":[{"gene_uniquename":"YMR246W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03471","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR246W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03471","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR246W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03909","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR246W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03909","reference_uniquename":"PMID:26896847"}],"product":"Long chain fatty acyl-CoA synthetase; activates fatty acids with a preference for C12:0-C16:0 chain lengths; role in the competitive import of long-chain fatty acids and sphingoid long-chain bases; role in stationary phase survival; localizes to lipid particles and the plasma membrane; role in sphingolipid-to-glycerolipid metabolism; forms cytoplasmic foci upon replication stress; faa1 faa4 double null complemented by any of human ACSBG1, ACSL1, 3, 4, 5, 6, SLC27A2, or 4","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004860","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR246W"}


id: YMR247C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00188":null,"YMR247C":null},"has_protein_features":false,"name":"RKR1","ortholog_annotations":[{"gene_uniquename":"YMR247C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00188","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR247C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00188","reference_uniquename":"PMID:26896847"}],"product":"RING domain E3 ubiquitin ligase; involved in ubiquitin-mediated degradation of non-stop proteins and translationally stalled ER membrane proteins; component of ribosome-bound RQC (ribosome quality control) complex; degrades products of mRNAs lacking a termination codon regardless of a poly(A) tail; functional connections to chromatin modification; homolog of mouse Listerin, mutations in which reported to cause neurodegeneration","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004861","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR247C"}


id: YMR247W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole","secondary_identifier":"SGD:S000028849","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR247W-A"}


id: YMR250W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"GAD1","product":"Glutamate decarboxylase; converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress","secondary_identifier":"SGD:S000004862","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR250W"}


id: YMR251W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"GTO3","product":"Omega class glutathione transferase; putative cytosolic localization","secondary_identifier":"SGD:S000004863","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR251W"}


id: YMR251W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"HOR7","product":"Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor; HOR7 has a paralog, DDR2, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004864","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR251W-A"}


id: YMR252C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"MLO1","product":"Mitochondrial protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; MLO1 is not an essential gene","secondary_identifier":"SGD:S000004865","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR252C"}


id: YMR253C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative membrane protein, involved in salt tolerance; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene","secondary_identifier":"SGD:S000004866","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR253C"}


id: YMR254C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; conserved across S. cerevisiae strains","secondary_identifier":"SGD:S000004867","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR254C"}


id: YMR255W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"GFD1","product":"Coiled-coiled protein of unknown function; identified as a high-copy suppressor of a dbp5 mutation; protein abundance increases in response to DNA replication stress","secondary_identifier":"SGD:S000004868","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR255W"}


id: YMR256C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05629":null,"YMR256C":null},"has_protein_features":false,"name":"COX7","ortholog_annotations":[{"gene_uniquename":"YMR256C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05629","reference_uniquename":"PMID:29761456"}],"product":"Subunit VII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004869","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR256C"}


id: YMR257C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"PET111","product":"Mitochondrial translational activator specific for the COX2 mRNA; located in the mitochondrial inner membrane","secondary_identifier":"SGD:S000004870","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR257C"}


id: YMR258C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ROY1","product":"GTPase inhibitor with similarity to F-box proteins; inhibits Ypt52p GTPase activity by preventing Ypt52p from binding GTP; involved in regulating intracellular trafficking; physically interacts with Skp1p","secondary_identifier":"SGD:S000004871","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR258C"}


id: YMR259C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04649":null,"YMR259C":null},"has_protein_features":false,"name":"TRM732","ortholog_annotations":[{"gene_uniquename":"YMR259C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04649","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR259C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04649","reference_uniquename":"PMID:26896847"}],"product":"Protein involved in 2'-O-methylation of C32 of substrate tRNAs; interacts with 2'-O-ribose methyltransferase Trm7p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; non-essential gene; yeast null mutant can be functionally complemented by human THADA, mutations in which have been implicated in epithelial thyroid adenomas, type 2 diabetes, and polycystic ovary syndrome (PCOS)","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004872","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR259C"}


id: YMR260C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01643":null,"YMR260C":null},"has_protein_features":false,"name":"TIF11","ortholog_annotations":[{"gene_uniquename":"YMR260C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01643","reference_uniquename":"PMID:29761456"}],"product":"Translation initiation factor eIF1A; essential protein that forms a complex with Sui1p (eIF1) and 40S ribosomal subunit and scans for start codons; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3; ortholog of bacterial translation initiation factor IF1","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004873","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR260C"}


id: YMR261C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00129":null,"SJAG_00182":null,"SJAG_01427":null,"YMR261C":null},"has_protein_features":false,"name":"TPS3","ortholog_annotations":[{"gene_uniquename":"YMR261C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00129","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR261C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00129","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR261C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00182","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR261C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01427","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR261C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01427","reference_uniquename":"PMID:26896847"}],"product":"Regulatory subunit of trehalose-6-phosphate synthase/phosphatase; involved in synthesis of storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway; TPS3 has a paralog, TSL1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004874","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR261C"}


id: YMR262W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03868":null,"YMR262W":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YMR262W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03868","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR262W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03868","reference_uniquename":"PMID:26896847"}],"product":"Protein of unknown function; interacts weakly with Knr4p; YMR262W is not an essential gene","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004875","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR262W"}


id: YMR263W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SAP30","product":"Component of Rpd3L histone deacetylase complex; involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance","secondary_identifier":"SGD:S000004876","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR263W"}


id: YMR264W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01051":null,"YMR264W":null},"has_protein_features":false,"name":"CUE1","ortholog_annotations":[{"gene_uniquename":"YMR264W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01051","reference_uniquename":"PMID:29761456"}],"product":"Ubiquitin-binding protein; ER membrane protein that recruits and integrates the ubiquitin-conjugating enzyme Ubc7p into ER membrane-bound ubiquitin ligase complexes that function in the ER-associated degradation (ERAD) pathway for misfolded proteins; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination and to promote diubiquitin elongation, facilitating polyubiquitin chain formation","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004877","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR264W"}


id: YMR265C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02350":null,"YMR265C":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YMR265C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02350","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR265C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02350","reference_uniquename":"PMID:26896847"}],"product":"Putative protein of unknown function","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004878","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR265C"}


id: YMR266W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02322":null,"YMR266W":null},"has_protein_features":false,"name":"RSN1","ortholog_annotations":[{"gene_uniquename":"YMR266W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02322","reference_uniquename":"PMID:29761456"}],"product":"Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant cells by restoring sodium pump (Ena1p) localization to the plasma membrane","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004879","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR266W"}


id: YMR267W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01875":null,"YMR267W":null},"has_protein_features":false,"name":"PPA2","ortholog_annotations":[{"gene_uniquename":"YMR267W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01875","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR267W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01875","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial inorganic pyrophosphatase; required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate; human ortholog, PPA2, functionally complements the null mutant; mutations in human PPA2 cause a mitochondrial disease resulting in sudden unexpected cardiac arrest in infants","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004880","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR267W"}


id: YMR268C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03214":null,"YMR268C":null},"has_protein_features":false,"name":"PRP24","ortholog_annotations":[{"gene_uniquename":"YMR268C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03214","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR268C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03214","reference_uniquename":"PMID:26896847"}],"product":"Splicing factor that reanneals snRNPs during spliceosome recycling; reanneals U4 and U6 snRNPs","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004881","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR268C"}


id: YMR268W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Merged open reading frame; does not encode a protein; YMR268W-A was originally annotated as an independent ORF, but as a result of a sequence change, it was merged with an adjacent ORF into a single reading frame, designated YMR269W","secondary_identifier":"SGD:S000028577","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR268W-A"}


id: YMR269W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02775":null,"YMR269W":null},"has_protein_features":false,"name":"TMA23","ortholog_annotations":[{"gene_uniquename":"YMR269W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02775","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR269W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02775","reference_uniquename":"PMID:26896847"}],"product":"Nucleolar protein implicated in ribosome biogenesis; deletion extends chronological lifespan","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004882","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR269W"}


id: YMR270C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04083":null,"YMR270C":null},"has_protein_features":false,"name":"RRN9","ortholog_annotations":[{"gene_uniquename":"YMR270C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04083","reference_uniquename":"PMID:29761456"}],"product":"Protein involved in promoting high level transcription of rDNA; subunit of UAF (upstream activation factor) for RNA polymerase I","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004883","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR270C"}


id: YMR271C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00694":null,"YMR271C":null},"has_protein_features":false,"name":"URA10","ortholog_annotations":[{"gene_uniquename":"YMR271C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00694","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR271C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00694","reference_uniquename":"PMID:26896847"}],"product":"Minor orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA10 has a paralog, URA5, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004884","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR271C"}


id: YMR272C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04913":null,"YMR272C":null},"has_protein_features":false,"name":"SCS7","ortholog_annotations":[{"gene_uniquename":"YMR272C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04913","reference_uniquename":"PMID:29761456"}],"product":"Sphingolipid alpha-hydroxylase; functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004885","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR272C"}


id: YMR272W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the verified gene SCS7/YMR272C","secondary_identifier":"SGD:S000028695","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR272W-A"}


id: YMR272W-B
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole","secondary_identifier":"SGD:S000028696","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR272W-B"}


id: YMR273C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01901":null,"YMR273C":null},"has_protein_features":false,"name":"ZDS1","ortholog_annotations":[{"gene_uniquename":"YMR273C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01901","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR273C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01901","reference_uniquename":"PMID:26896847"}],"product":"Protein with a role in regulating Swe1p-dependent polarized growth; involved in maintaining Cdc55p in the cytoplasm where it promotes mitotic entry; involved in mitotic exit through Cdc14p regulation; interacts with silencing proteins at telomeres; has a role in Bcy1p localization; implicated in mRNA nuclear export; ZDS1 has a paralog, ZDS2, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004886","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR273C"}


id: YMR274C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00730":null,"YMR274C":null},"has_protein_features":false,"name":"RCE1","ortholog_annotations":[{"gene_uniquename":"YMR274C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00730","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR274C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00730","reference_uniquename":"PMID:26896847"}],"product":"Type II CAAX prenyl protease; involved in the proteolysis and maturation of Ras and the a-factor mating pheromone","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004887","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR274C"}


id: YMR275C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"BUL1","product":"Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex; ubiquitin-binding adaptor involved in down-regulation of general amino acid transporter Gap1p upon shift to preferred nitrogen source; involved in lactate transporter Jen1p endocytosis; BUL1 has a paralog, BUL2, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004888","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR275C"}


id: YMR276W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_07000":null,"YMR276W":null},"has_protein_features":false,"name":"DSK2","ortholog_annotations":[{"gene_uniquename":"YMR276W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_07000","reference_uniquename":"PMID:29761456"}],"product":"Nuclear-enriched ubiquitin-like polyubiquitin-binding protein; K48-Ub chain binding protein that also binds K63-linked chains in vitro; required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle; involved in proteolysis; interacts with the proteasome; contains an N-terminal Ub-like (UBL) and a C-terminal Ub-associated (UBA) domain; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004889","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR276W"}


id: YMR277W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01286":null,"YMR277W":null},"has_protein_features":false,"name":"FCP1","ortholog_annotations":[{"gene_uniquename":"YMR277W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01286","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR277W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01286","reference_uniquename":"PMID:26896847"}],"product":"Carboxy-terminal domain (CTD) phosphatase; essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p); relocalizes to the cytosol in response to hypoxia","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004890","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR277W"}


id: YMR278W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00134":null,"YMR278W":null},"has_protein_features":false,"name":"PRM15","ortholog_annotations":[{"gene_uniquename":"YMR278W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00134","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR278W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00134","reference_uniquename":"PMID:26896847"}],"product":"Phosphoribomutase; catalyzes interconversion of ribose-1-phosphate and ribose-5-phosphate; has some phosphoglucomutase activity but primary activity in vivo is phosphoribomutase; contributes to ribose recycling in the pentose phosphate pathway; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004891","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR278W"}


id: YMR279C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ATR2","product":"Putative boron transporter involved in boron efflux and resistance; overexpression mutant but not null mutant displays boron tolerance phenotype; identified as a heat-induced gene in a high-throughout screen; YMR279C is not an essential gene; YMR279C has a paralog, ATR1, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004892","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR279C"}


id: YMR280C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"CAT8","product":"Zinc cluster transcriptional activator; necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements; relative distribution to the nucleus increases upon DNA replication stress","secondary_identifier":"SGD:S000004893","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR280C"}


id: YMR281W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01416":null,"YMR281W":null},"has_protein_features":false,"name":"GPI12","ortholog_annotations":[{"gene_uniquename":"YMR281W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01416","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR281W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01416","reference_uniquename":"PMID:26896847"}],"product":"ER membrane protein involved in the second step of GPI anchor assembly; the second step is the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp; GPI stands for glycosylphosphatidylinositol","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004894","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR281W"}


id: YMR282C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03674":null,"YMR282C":null},"has_protein_features":false,"name":"AEP2","ortholog_annotations":[{"gene_uniquename":"YMR282C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03674","reference_uniquename":"PMID:29761456"}],"product":"Mitochondrial protein; likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004895","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR282C"}


id: YMR283C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05228":null,"YMR283C":null},"has_protein_features":false,"name":"RIT1","ortholog_annotations":[{"gene_uniquename":"YMR283C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05228","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR283C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05228","reference_uniquename":"PMID:26896847"}],"product":"Initiator methionine 2'-O-ribosyl phosphate transferase; modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004896","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR283C"}


id: YMR284W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05372":null,"YMR284W":null},"has_protein_features":false,"name":"YKU70","ortholog_annotations":[{"gene_uniquename":"YMR284W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05372","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR284W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05372","reference_uniquename":"PMID:26896847"}],"product":"Subunit of the telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein to nucleus via interaction with the TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004897","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR284W"}


id: YMR285C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04519":null,"YMR285C":null},"has_protein_features":false,"name":"NGL2","ortholog_annotations":[{"gene_uniquename":"YMR285C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04519","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR285C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04519","reference_uniquename":"PMID:26896847"}],"product":"Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p; NGL2 has a paralog, NGL3, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004898","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR285C"}


id: YMR286W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_06253":null,"YMR286W":null},"has_protein_features":false,"name":"MRPL33","ortholog_annotations":[{"gene_uniquename":"YMR286W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06253","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR286W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06253","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial ribosomal protein of the large subunit","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004899","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR286W"}


id: YMR287C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_06586":null,"YMR287C":null},"has_protein_features":false,"name":"DSS1","ortholog_annotations":[{"gene_uniquename":"YMR287C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06586","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR287C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06586","reference_uniquename":"PMID:26896847"}],"product":"3'-5' exoribonuclease; component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004900","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR287C"}


id: YMR288W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01008":null,"YMR288W":null},"has_protein_features":false,"name":"HSH155","ortholog_annotations":[{"gene_uniquename":"YMR288W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01008","reference_uniquename":"PMID:29761456"}],"product":"U2-snRNP associated splicing factor; forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004901","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR288W"}


id: YMR289W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02225":null,"YMR289W":null},"has_protein_features":false,"name":"ABZ2","ortholog_annotations":[{"gene_uniquename":"YMR289W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02225","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR289W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02225","reference_uniquename":"PMID:26896847"}],"product":"Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase); catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004902","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR289W"}


id: YMR290C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04669":null,"YMR290C":null},"has_protein_features":false,"name":"HAS1","ortholog_annotations":[{"gene_uniquename":"YMR290C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04669","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR290C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04669","reference_uniquename":"PMID:26896847"}],"product":"ATP-dependent RNA helicase; involved in the biogenesis of 40S and 60S ribosome subunits; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004903","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR290C"}


id: YMR290W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1/YMR290C gene which encodes an ATP-dependent RNA helicase","secondary_identifier":"SGD:S000004904","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR290W-A"}


id: YMR291W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"TDA1","product":"Protein serine/threonine kinase; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress","secondary_identifier":"SGD:S000004905","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR291W"}


id: YMR292W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04112":null,"YMR292W":null},"has_protein_features":false,"name":"GOT1","ortholog_annotations":[{"gene_uniquename":"YMR292W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04112","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR292W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04112","reference_uniquename":"PMID:26896847"}],"product":"Homodimeric protein that is packaged into COPII vesicles; cycles between the ER and Golgi; involved in secretory transport but not directly required for aspects of transport assayed in vitro; may influence membrane composition","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004906","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR292W"}


id: YMR293C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02721":null,"YMR293C":null},"has_protein_features":false,"name":"HER2","ortholog_annotations":[{"gene_uniquename":"YMR293C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02721","reference_uniquename":"PMID:29761456"}],"product":"Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004907","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR293C"}


id: YMR294W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03673":null,"YMR294W":null},"has_protein_features":false,"name":"JNM1","ortholog_annotations":[{"gene_uniquename":"YMR294W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03673","reference_uniquename":"PMID:29761456"}],"product":"Component of the yeast dynactin complex; consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004908","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR294W"}


id: YMR294W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; substantially overlaps YMR295C; deletion causes sensitivity to unfolded protein response-inducing agents","secondary_identifier":"SGD:S000004909","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR294W-A"}


id: YMR295C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01255":null,"SJAG_04659":null,"YMR295C":null},"has_protein_features":false,"name":"GSR1","ortholog_annotations":[{"gene_uniquename":"YMR295C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01255","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR295C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04659","reference_uniquename":"PMID:29761456"}],"product":"Putative regulator of 1,3-beta-glucan biosynthesis; interacts with the catalytic (Fks1p and Gsc2p) and regulatory subunits (Rho1p) of 1,3-beta-glucan synthase; has a negative genetic interaction with RHO1; localizes to the cell periphery during early G1, to the bud tip in late G1, to the bud at S/G2, to the periphery of the bud at metaphase and at the bud neck during telophase; periodically expressed during the cell cycle; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004910","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR295C"}


id: YMR296C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04178":null,"YMR296C":null},"has_protein_features":false,"name":"LCB1","ortholog_annotations":[{"gene_uniquename":"YMR296C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04178","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR296C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04178","reference_uniquename":"PMID:26896847"}],"product":"Component of serine palmitoyltransferase; responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004911","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR296C"}


id: YMR297W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01868":null,"YMR297W":null},"has_protein_features":false,"name":"PRC1","ortholog_annotations":[{"gene_uniquename":"YMR297W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01868","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR297W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01868","reference_uniquename":"PMID:26896847"}],"product":"Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in vacuole; involved, along with functional homolog Prc1p, in vacuolar zymogen activation, breakdown of autophagic body, and autophagosome-dependent protein synthesis; role in phytochelatin synthesis; targeted to vacuole via Vps10p-dependent endosomal vacuolar protein sorting pathway; member of serine carboxypeptidase family; N-glycosylated","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004912","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR297W"}


id: YMR298W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"LIP1","product":"Ceramide synthase subunit; single-span ER membrane protein associated with Lag1p and Lac1p and required for ceramide synthase activity, null mutant grows extremely slowly and is defective in ceramide synthesis","secondary_identifier":"SGD:S000004913","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR298W"}


id: YMR299C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00113":null,"YMR299C":null},"has_protein_features":false,"name":"DYN3","ortholog_annotations":[{"gene_uniquename":"YMR299C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00113","reference_uniquename":"PMID:29761456"}],"product":"Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004914","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR299C"}


id: YMR300C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01661":null,"YMR300C":null},"has_protein_features":false,"name":"ADE4","ortholog_annotations":[{"gene_uniquename":"YMR300C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01661","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR300C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01661","reference_uniquename":"PMID:26896847"}],"product":"Phosphoribosylpyrophosphate amidotransferase (PRPPAT); catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway; also known as amidophosphoribosyltransferase","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004915","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR300C"}


id: YMR301C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02457":null,"YMR301C":null},"has_protein_features":false,"name":"ATM1","ortholog_annotations":[{"gene_uniquename":"YMR301C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02457","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR301C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02457","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial inner membrane ATP-binding cassette (ABC) transporter; exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol; human homolog ABCB7 can complement yeast null mutant","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004916","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR301C"}


id: YMR302C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03038":null,"YMR302C":null},"has_protein_features":false,"name":"YME2","ortholog_annotations":[{"gene_uniquename":"YMR302C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03038","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR302C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03038","reference_uniquename":"PMID:26896847"}],"product":"Integral inner mitochondrial membrane protein; role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004917","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR302C"}


id: YMR303C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01414":null,"SJAG_03370":null,"YMR303C":null},"has_protein_features":false,"name":"ADH2","ortholog_annotations":[{"gene_uniquename":"YMR303C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01414","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR303C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03370","reference_uniquename":"PMID:29761456"}],"product":"Glucose-repressible alcohol dehydrogenase II; catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004918","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR303C"}


id: YMR304C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps 3' end of verified ORF SCW10/YMR305C","secondary_identifier":"SGD:S000004919","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR304C-A"}


id: YMR304W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00573":null,"SJAG_03686":null,"YMR304W":null},"has_protein_features":false,"name":"UBP15","ortholog_annotations":[{"gene_uniquename":"YMR304W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00573","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR304W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00573","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR304W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03686","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR304W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03686","reference_uniquename":"PMID:26896847"}],"product":"Ubiquitin-specific protease involved in protein deubiquitination; forms a complex with AAA peroxins Pex1p and Pex6p; deubiquitinates mono- and polyubiquitinated forms of Pex5p; deubiquitinates Clb5p, counteracting APC activity, and facilitating both Clb5p accumulation and S phase entry; physically interacts with anaphase-promoting complex/cyclosome (APC/C) activator, Cdh1p; catalytic activity regulated by an N-terminal TRAF-like domain and and C-terminal sequences","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004920","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR304W"}


id: YMR305C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SCW10","product":"Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p; SWC10 has a paralog, SCW4, that arose from the whole genome duplication","secondary_identifier":"SGD:S000004921","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR305C"}


id: YMR306C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps 3' end of ORF FKS3/YMR306W","secondary_identifier":"SGD:S000004922","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR306C-A"}


id: YMR306W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01288":null,"SJAG_02222":null,"SJAG_03587":null,"SJAG_05285":null,"YMR306W":null},"has_protein_features":false,"name":"FKS3","ortholog_annotations":[{"gene_uniquename":"YMR306W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01288","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR306W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02222","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR306W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03587","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR306W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05285","reference_uniquename":"PMID:29761456"}],"product":"Protein involved in spore wall assembly; has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004923","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR306W"}


id: YMR307C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene GAS1/YMR307W","secondary_identifier":"SGD:S000028578","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR307C-A"}


id: YMR307W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01290":null,"YMR307W":null},"has_protein_features":false,"name":"GAS1","ortholog_annotations":[{"gene_uniquename":"YMR307W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01290","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR307W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01290","reference_uniquename":"PMID:26896847"}],"product":"Beta-1,3-glucanosyltransferase required for cell wall assembly; also has role in transcriptional silencing; localizes to cell surface via glycosylphosphatidylinositol (GPI) anchor, also found at nuclear periphery; genetic interactions with histone H3 lysine acetyltransferases GCN5 and SAS3 indicate functions for Gas1p in DNA damage response and cell cycle regulation; protein demonstrates amyloid properties in vivo","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004924","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR307W"}


id: YMR308C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02998":null,"YMR308C":null},"has_protein_features":false,"name":"PSE1","ortholog_annotations":[{"gene_uniquename":"YMR308C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02998","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR308C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02998","reference_uniquename":"PMID:26896847"}],"product":"Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p; required for stability of the Dam1p-Duo1p complex","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004925","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR308C"}


id: YMR309C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04981":null,"YMR309C":null},"has_protein_features":false,"name":"NIP1","ortholog_annotations":[{"gene_uniquename":"YMR309C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04981","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR309C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04981","reference_uniquename":"PMID:26896847"}],"product":"eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3); involved in the assembly of preinitiation complex and start codon selection; eIF3 is also involved in programmed stop codon readthrough","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004926","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR309C"}


id: YMR310C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03554":null,"YMR310C":null},"has_protein_features":false,"name":"UPA2","ortholog_annotations":[{"gene_uniquename":"YMR310C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03554","reference_uniquename":"PMID:29761456"}],"product":"Putative SPOUT methyltransferase; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; not an essential gene; YMR310C has a paralog, YGR283C, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004927","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR310C"}


id: YMR311C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03272":null,"YMR311C":null},"has_protein_features":false,"name":"GLC8","ortholog_annotations":[{"gene_uniquename":"YMR311C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03272","reference_uniquename":"PMID:29761456"}],"product":"Regulatory subunit of protein phosphatase 1 (Glc7p); involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004928","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR311C"}


id: YMR312W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04452":null,"YMR312W":null},"has_protein_features":false,"name":"ELP6","ortholog_annotations":[{"gene_uniquename":"YMR312W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04452","reference_uniquename":"PMID:29761456"}],"product":"Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004929","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR312W"}


id: YMR313C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02487":null,"YMR313C":null},"has_protein_features":false,"name":"TGL3","ortholog_annotations":[{"gene_uniquename":"YMR313C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02487","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR313C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02487","reference_uniquename":"PMID:26896847"}],"product":"Bifunctional triacylglycerol lipase and LPE acyltransferase; major lipid particle-localized triacylglycerol (TAG) lipase; catalyzes acylation of lysophosphatidylethanolamine (LPE), a function which is essential for sporulation; protein level and stability of Tgl3p are markedly reduced in the absence of lipid droplets; required with Tgl4p for timely bud formation","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004930","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR313C"}


id: YMR314W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04357":null,"YMR314W":null},"has_protein_features":false,"name":"PRE5","ortholog_annotations":[{"gene_uniquename":"YMR314W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04357","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR314W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04357","reference_uniquename":"PMID:26896847"}],"product":"Alpha 6 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004931","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR314W"}


id: YMR315W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02154":null,"SJAG_02191":null,"YMR315W":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YMR315W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02154","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR315W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02154","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR315W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02191","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR315W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02191","reference_uniquename":"PMID:29761456"}],"product":"Protein with NADP(H) oxidoreductase activity; transcription is regulated by Stb5p in response to NADPH depletion induced by diamide; promoter contains an Stb5p binding site and Stb5p binding is enriched at the promoter; negative regulator of nonselective autophagy; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004932","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR315W"}


id: YMR315W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function","secondary_identifier":"SGD:S000028697","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR315W-A"}


id: YMR316C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; mRNA identified as translated by ribosome profiling data; overlaps the verified gene DIA1/YMR316W","secondary_identifier":"SGD:S000004933","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR316C-A"}


id: YMR316C-B
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps 5' end of ORF YMR317W","secondary_identifier":"SGD:S000004934","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR316C-B"}


id: YMR316W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"DIA1","product":"Protein of unknown function; involved in invasive and pseudohyphal growth; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern","secondary_identifier":"SGD:S000004935","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR316W"}


id: YMR317W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; YMR317W is not an essential gene","secondary_identifier":"SGD:S000004936","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR317W"}


id: YMR318C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02963":null,"YMR318C":null},"has_protein_features":false,"name":"ADH6","ortholog_annotations":[{"gene_uniquename":"YMR318C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02963","reference_uniquename":"PMID:26896847"}],"product":"NADPH-dependent medium chain alcohol dehydrogenase; has broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null},"secondary_identifier":"SGD:S000004937","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR318C"}


id: YMR319C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02968":null,"YMR319C":null},"has_protein_features":false,"name":"FET4","ortholog_annotations":[{"gene_uniquename":"YMR319C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02968","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR319C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02968","reference_uniquename":"PMID:26896847"}],"product":"Low-affinity Fe(II) transporter of the plasma membrane","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004938","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR319C"}


id: YMR320W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; conserved among S. cerevisiae strains; YMR320W is not an essential gene","secondary_identifier":"SGD:S000004939","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR320W"}


id: YMR321C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04425":null,"YMR321C":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YMR321C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04425","reference_uniquename":"PMID:26896847"}],"product":"Putative protein of unknown function; proposed to be a palmitoylated membrane protein; YMR321C has a paralog, SAM4, that arose from a single-locus duplication","references_by_uniquename":{"PMID:26896847":null},"secondary_identifier":"SGD:S000004940","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR321C"}


id: YMR322C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02988":null,"SJAG_04674":null,"YMR322C":null},"has_protein_features":false,"name":"SNO4","ortholog_annotations":[{"gene_uniquename":"YMR322C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02988","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR322C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02988","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR322C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02988","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR322C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04674","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR322C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04674","reference_uniquename":"PMID:26896847"}],"product":"Possible chaperone and cysteine protease; required for transcriptional reprogramming during the diauxic shift and for survival in stationary phase; similar to bacterial Hsp31 and yeast Hsp31p, Hsp32p, and Hsp33p; DJ-1/ThiJ/PfpI superfamily member; predicted involvement in pyridoxine metabolism; induced by mild heat stress and copper deprivation","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004941","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR322C"}


id: YMR323W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00461":null,"SJAG_02107":null,"SJAG_02369":null,"YMR323W":null},"has_protein_features":false,"name":"ERR3","ortholog_annotations":[{"gene_uniquename":"YMR323W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00461","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR323W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00461","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR323W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02107","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR323W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02107","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YMR323W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02369","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YMR323W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02369","reference_uniquename":"PMID:26896847"}],"product":"Enolase, a phosphopyruvate hydratase; catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate; complements the growth defect of an ENO1 ENO2 double mutant in glucose","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004942","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR323W"}


id: YMR324C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; transcription is AZF1 dependent in glycerol-lactate medium and SLT2 dependent in response to the lipid hydroperoxides","secondary_identifier":"SGD:S000004943","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR324C"}


id: YMR325W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"PAU19","product":"Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions","secondary_identifier":"SGD:S000004944","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR325W"}


id: YMR326C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the telomere on the right arm of chromosome 13","secondary_identifier":"SGD:S000004945","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YMR326C"}


id: YNCA0001W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"HRA1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCA0001W"}


id: YNCA0003W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR18","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCA0003W"}


id: YNCB0003W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR56","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCB0003W"}


id: YNCB0008W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCB0008W"}


id: YNCB0009C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR161","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCB0009C"}


id: YNCB0014W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"TBRT","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCB0014W"}


id: YNCC0003C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR43","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCC0003C"}


id: YNCC0006C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR33","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCC0006C"}


id: YNCC0011W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR65","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCC0011W"}


id: YNCC0012C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR189","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCC0012C"}


id: YNCC0015W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT035","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCC0015W"}


id: YNCD0002C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR63","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCD0002C"}


id: YNCD0010C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR47","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCD0010C"}


id: YNCD0030W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR13","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCD0030W"}


id: YNCD0032C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR84","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCD0032C"}


id: YNCD0033W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT053","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCD0033W"}


id: YNCD0034C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT468","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCD0034C"}


id: YNCE0001C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR80","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0001C"}


id: YNCE0002W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR67","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0002W"}


id: YNCE0003W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR53","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0003W"}


id: YNCE0007C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RPR1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0007C"}


id: YNCE0017W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SRG1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0017W"}


id: YNCE0019W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR4","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0019W"}


id: YNCE0020C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR52","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0020C"}


id: YNCE0024W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SCR1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCE0024W"}


id: YNCF0001C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RUF21","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCF0001C"}


id: YNCF0003C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RUF20","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCF0003C"}


id: YNCF0010C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RUF22","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCF0010C"}


id: YNCF0013W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RUF23","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCF0013W"}


id: YNCG0001C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RME3","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0001C"}


id: YNCG0006C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RME2","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0006C"}


id: YNCG0010W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR82","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0010W"}


id: YNCG0013W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR10","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0013W"}


id: YNCG0014C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR39","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0014C"}


id: YNCG0015C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR39B","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0015C"}


id: YNCG0024W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR46","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0024W"}


id: YNCG0026W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR48","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0026W"}


id: YNCG0047C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT532","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0047C"}


id: YNCG0048W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT125","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0048W"}


id: YNCG0049W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT126","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCG0049W"}


id: YNCH0007W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RUF5-1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCH0007W"}


id: YNCH0008W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RUF5-2","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCH0008W"}


id: YNCH0011W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT169","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCH0011W"}


id: YNCH0012W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR32","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCH0012W"}


id: YNCH0014W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR71","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCH0014W"}


id: YNCI0001W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR68","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCI0001W"}


id: YNCI0012
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ICR1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCI0012"}


id: YNCI0013W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"PWR1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCI0013W"}


id: YNCJ0003C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR128","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCJ0003C"}


id: YNCJ0004C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR190","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCJ0004C"}


id: YNCJ0007C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR37","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCJ0007C"}


id: YNCJ0009C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR60","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCJ0009C"}


id: YNCJ0028C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"IRT1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCJ0028C"}


id: YNCJ0030W
data:
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id: YNCK0001W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR64","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCK0001W"}


id: YNCK0009W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR38","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCK0009W"}


id: YNCK0013W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR69","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCK0013W"}


id: YNCK0015C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR87","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCK0015C"}


id: YNCK0020C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR42","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCK0020C"}


id: YNCL0003W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR30","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCL0003W"}


id: YNCL0005C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR79","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCL0005C"}


id: YNCL0041C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR61","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCL0041C"}


id: YNCL0042C
data:
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id: YNCL0043C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR57","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCL0043C"}


id: YNCL0046W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR44","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCL0046W"}


id: YNCL0048W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR34","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCL0048W"}


id: YNCM0001W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0001W"}


id: YNCM0002C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR85","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0002C"}


id: YNCM0003W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ZOD1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0003W"}


id: YNCM0005C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR54","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0005C"}


id: YNCM0011W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR78","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0011W"}


id: YNCM0012W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR77","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0012W"}


id: YNCM0013W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR76","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0013W"}


id: YNCM0014W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR75","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0014W"}


id: YNCM0015W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR74","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0015W"}


id: YNCM0016W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR73","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0016W"}


id: YNCM0017W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR72","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0017W"}


id: YNCM0026C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR24","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0026C"}


id: YNCM0030W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR83","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0030W"}


id: YNCM0031W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR11","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0031W"}


id: YNCM0032C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RNA170","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0032C"}


id: YNCM0034C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR86","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCM0034C"}


id: YNCN0001W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR40","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCN0001W"}


id: YNCN0013W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"NME1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCN0013W"}


id: YNCN0014W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR66","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCN0014W"}


id: YNCN0018W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR49","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCN0018W"}


id: YNCN0019C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR191","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCN0019C"}


id: YNCO0003C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR58","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0003C"}


id: YNCO0006W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR81","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0006W"}


id: YNCO0007W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR50","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0007W"}


id: YNCO0014C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR9","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0014C"}


id: YNCO0015C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR62","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0015C"}


id: YNCO0022C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR36","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0022C"}


id: YNCO0024C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR35","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0024C"}


id: YNCO0025W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR17A","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0025W"}


id: YNCO0026W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR8","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0026W"}


id: YNCO0027C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR31","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0027C"}


id: YNCO0028W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR5","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCO0028W"}


id: YNCP0002W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0002W"}


id: YNCP0003W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR59","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0003W"}


id: YNCP0005C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR17B","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0005C"}


id: YNCP0013C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR51","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0013C"}


id: YNCP0014C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR70","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0014C"}


id: YNCP0015C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR41","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0015C"}


id: YNCP0021W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNR45","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0021W"}


id: YNCP0025W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SUT390","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCP0025W"}


id: YNCP0026W
data:
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id: YNCQ0027W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RPM1","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNCQ0027W"}


id: YNL001W
data:
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id: YNL002C
data:
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id: YNL003C
data:
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id: YNL004W
data:
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id: YNL005C
data:
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id: YNL006W
data:
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id: YNL007C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03794":null,"YNL007C":null},"has_protein_features":false,"name":"SIS1","ortholog_annotations":[{"gene_uniquename":"YNL007C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03794","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL007C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03794","reference_uniquename":"PMID:26896847"}],"product":"Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; shuttles between cytosol and nucleus; mediates delivery of misfolded proteins into the nucleus for degradation; involved in proteasomal degradation of misfolded cytosolic proteins; protein abundance increases in response to DNA replication stress; polyQ aggregates sequester Sis1p and interfere with clearance of misfolded proteins; similar to bacterial DnaJ proteins and mammalian DnaJB1","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004952","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL007C"}


id: YNL008C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ASI3","product":"Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and regulators of sterol biosynthesis for ubiquitin-mediated degradation; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids","secondary_identifier":"SGD:S000004953","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL008C"}


id: YNL009W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04362":null,"YNL009W":null},"has_protein_features":false,"name":"IDP3","ortholog_annotations":[{"gene_uniquename":"YNL009W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04362","reference_uniquename":"PMID:29761456"}],"product":"Peroxisomal NADP-dependent isocitrate dehydrogenase; catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids; IDP3 has a paralog, IDP2, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004954","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL009W"}


id: YNL010W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04964":null,"YNL010W":null},"has_protein_features":false,"name":"PYP1","ortholog_annotations":[{"gene_uniquename":"YNL010W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04964","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL010W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04964","reference_uniquename":"PMID:26896847"}],"product":"Sugar alcohol phosphatase; polyol phosphatase that hydrolyzes sorbitol-6-phosphate, ribitol-5-phosphate, and (D)-glycerol-3-phosphate, maintaining phosphoglucose isomerase (PGI) activity in the presence of PGI-inhibitory sugar alcohols; expression correlated with growth rate; GFP-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant displays increased glycogen accumulation; member of the haloacid dehalogenase (HAD) superfamily","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004955","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL010W"}


id: YNL011C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; YNL011C is not an essential gene","secondary_identifier":"SGD:S000004956","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL011C"}


id: YNL012W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SPO1","product":"Meiosis-specific prospore protein; required for meiotic spindle pole body duplication and separation; required to produce bending force necessary for proper prospore membrane assembly during sporulation; has similarity to phospholipase B","secondary_identifier":"SGD:S000004957","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL012W"}


id: YNL013C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF HEF3/YNL014W","secondary_identifier":"SGD:S000004958","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL013C"}


id: YNL014W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02738":null,"YNL014W":null},"has_protein_features":false,"name":"HEF3","ortholog_annotations":[{"gene_uniquename":"YNL014W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02738","reference_uniquename":"PMID:29761456"}],"product":"Translational elongation factor EF-3; member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells; HEF3 has a paralog, YEF3, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004959","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL014W"}


id: YNL015W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01072":null,"YNL015W":null},"has_protein_features":false,"name":"PBI2","ortholog_annotations":[{"gene_uniquename":"YNL015W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01072","reference_uniquename":"PMID:29761456"}],"product":"Cytosolic inhibitor of vacuolar proteinase B (PRB1); required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004960","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL015W"}


id: YNL016W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01440":null,"YNL016W":null},"has_protein_features":false,"name":"PUB1","ortholog_annotations":[{"gene_uniquename":"YNL016W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01440","reference_uniquename":"PMID:26896847"}],"product":"Poly (A)+ RNA-binding protein; abundant mRNP-component protein that binds cell wall mRNAs; required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; implicated in regulation of translation; carries Q/N-rich domain at C- terminus, identified as candidate prion; ribosome-bound Pub1p modulates stop codon decoding during translation termination","references_by_uniquename":{"PMID:26896847":null},"secondary_identifier":"SGD:S000004961","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL016W"}


id: YNL017C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the tRNA ORF tI(AAU)N2","secondary_identifier":"SGD:S000004962","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL017C"}


id: YNL018C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein required for sporulation; induced during meiosis and sporulation; gene is a member of Centroid, a centromere-linked gene family; YNL018C has a paralog, YNL034W, that arose from a segmental duplication","secondary_identifier":"SGD:S000004963","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL018C"}


id: YNL019C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; expression induced during heat stress; YNL019C has a paralog, YNL033W, that arose from a segmental duplication","secondary_identifier":"SGD:S000004964","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL019C"}


id: YNL020C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00649":null,"SJAG_04052":null,"SJAG_04465":null,"YNL020C":null},"has_protein_features":false,"name":"ARK1","ortholog_annotations":[{"gene_uniquename":"YNL020C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00649","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL020C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00649","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL020C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04052","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL020C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04052","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL020C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04465","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL020C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04465","reference_uniquename":"PMID:26896847"}],"product":"Ser/Thr protein kinase; phosphorylates Pan1p-Sla1p-End3p protein complex subunits, Pan1p and Sla1p; involved in regulation of the cortical actin cytoskeleton and endocytosis; functional overlap with PRK1","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004965","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL020C"}


id: YNL021W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03844":null,"YNL021W":null},"has_protein_features":false,"name":"HDA1","ortholog_annotations":[{"gene_uniquename":"YNL021W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03844","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL021W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03844","reference_uniquename":"PMID:26896847"}],"product":"Catalytic subunit of class II HDA1 histone deacetylase complex; role in azole resistance via Hsp90p, and in heat shock response; Hda1p interacts with Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation; the HDA1 histone deacetylase complex regulates aging through trehalose metabolism","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004966","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL021W"}


id: YNL022C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03877":null,"YNL022C":null},"has_protein_features":false,"name":"RCM1","ortholog_annotations":[{"gene_uniquename":"YNL022C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03877","reference_uniquename":"PMID:29761456"}],"product":"rRNA m5C methyltransferase; methylates cytosine at position 2278 of 25S rRNA while Nop2p methylates cytosine at position 2870; contains seven beta-strand methyltransferase motif; localized to the nucleolus; interacts with Trm112p; homolog of NSUN5A, a human gene which is deleted in Williams-Beuren Syndrome","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004967","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL022C"}


id: YNL023C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02752":null,"YNL023C":null},"has_protein_features":false,"name":"FAP1","ortholog_annotations":[{"gene_uniquename":"YNL023C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02752","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL023C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02752","reference_uniquename":"PMID:26896847"}],"product":"Protein that acts as sensor of stalled ribosomes; binds to Fpr1p and Smu2p, and triggers ubiquitination of stalled monosomes for subsequent degradation; confers rapamycin resistance by competing with rapamycin for Fpr1p binding; accumulates in the nucleus upon treatment of cells with rapamycin; has similarity to D. melanogaster shuttle craft and human NFX1","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004968","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL023C"}


id: YNL024C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"EFM6","product":"Putative S-adenosylmethionine-dependent lysine methyltransferase; responsible for modifying Lys-390 in translational elongation factor EF-1 alpha (eEF1A); has seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm","secondary_identifier":"SGD:S000004969","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL024C"}


id: YNL024C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05736":null,"YNL024C-A":null},"has_protein_features":false,"name":"KSH1","ortholog_annotations":[{"gene_uniquename":"YNL024C-A","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05736","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL024C-A","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05736","reference_uniquename":"PMID:26896847"}],"product":"Essential protein suggested to function early in the secretory pathway; inviability is suppressed by overexpression of Golgi protein Tvp23p; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and cytosol respectively; ortholog of human Kish","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000028698","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL024C-A"}


id: YNL025C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00613":null,"YNL025C":null},"has_protein_features":false,"name":"SSN8","ortholog_annotations":[{"gene_uniquename":"YNL025C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00613","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL025C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00613","reference_uniquename":"PMID:26896847"}],"product":"Cyclin-like component of RNA polymerase II holoenzyme; involved in phosphorylation of RNAPII C-terminal domain; forms kinase-cyclin pair in RNAPII holoenzyme with Ssn3p; needed for entry into and execution of meiotic program; involved in glucose repression, telomere maintenance; degraded in response to nitrogen starvation, and also to oxidative stress, but in different cellular compartments, and with different cellular outcomes; 35% identical to human cyclin C","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004970","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL025C"}


id: YNL026W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01951":null,"YNL026W":null},"has_protein_features":false,"name":"SAM50","ortholog_annotations":[{"gene_uniquename":"YNL026W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01951","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL026W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01951","reference_uniquename":"PMID:26896847"}],"product":"Component of the Sorting and Assembly Machinery (SAM) complex; the SAM (or TOB) complex is located in the mitochondrial outer membrane; the complex binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; homologous to bacterial Omp85","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004971","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL026W"}


id: YNL027W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03879":null,"YNL027W":null},"has_protein_features":false,"name":"CRZ1","ortholog_annotations":[{"gene_uniquename":"YNL027W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03879","reference_uniquename":"PMID:29761456"}],"product":"Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004972","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL027W"}


id: YNL028W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data","secondary_identifier":"SGD:S000004973","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL028W"}


id: YNL029C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02519":null,"SJAG_03082":null,"YNL029C":null},"has_protein_features":false,"name":"KTR5","ortholog_annotations":[{"gene_uniquename":"YNL029C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02519","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL029C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02519","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL029C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03082","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL029C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03082","reference_uniquename":"PMID:26896847"}],"product":"Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR5 has a paralog, KTR7, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004974","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL029C"}


id: YNL030W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00303":null,"SJAG_00336":null,"SJAG_03542":null,"YNL030W":null},"has_protein_features":false,"name":"HHF2","ortholog_annotations":[{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00303","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00303","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00303","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00336","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00336","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00336","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00336","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03542","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03542","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL030W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03542","reference_uniquename":"PMID:29761456"}],"product":"Histone H4; core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF1); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004975","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL030W"}


id: YNL031C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00302":null,"SJAG_00335":null,"SJAG_03543":null,"YNL031C":null},"has_protein_features":false,"name":"HHT2","ortholog_annotations":[{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00302","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00302","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00302","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00335","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00335","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00335","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03543","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03543","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL031C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03543","reference_uniquename":"PMID:26896847"}],"product":"Histone H3; core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT1); regulated by acetylation, methylation, and phosphorylation; H3K14 acetylation plays an important role in the unfolding of strongly positioned nucleosomes during repair of UV damage","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004976","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL031C"}


id: YNL032W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01154":null,"YNL032W":null},"has_protein_features":false,"name":"SIW14","ortholog_annotations":[{"gene_uniquename":"YNL032W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01154","reference_uniquename":"PMID:29761456"}],"product":"Inositol phosphatase involved in inositol pyrophosphate metabolism; hydrolyzes the beta-phosphate from the 5-diphosphate group of PP-InsPs including: 5PP-IP5 (IP7), 1,5PP-IP4 (IP8) and 5-PP-InsP4; functions as an anti-prion (anti-[PSI]) component; member of the atypical dual-specificity subgroup of the protein tyrosine-phosphatase (PTP) superfamily; localizes to the cytoplasm","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004977","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL032W"}


id: YNL033W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; YNL033W has a paralog, YNL019C, that arose from a segmental duplication","secondary_identifier":"SGD:S000004978","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL033W"}


id: YNL034W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein required for sporulation; induced during meiosis and sporulation; gene is a member of Centroid, a centromere-linked gene family; not an essential gene; YNL034W has a paralog, YNL018C, that arose from a segmental duplication","secondary_identifier":"SGD:S000004979","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL034W"}


id: YNL035C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04234":null,"YNL035C":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YNL035C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04234","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL035C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04234","reference_uniquename":"PMID:26896847"}],"product":"Nuclear protein of unknown function; relocalizes to the cytosol in response to hypoxia; contains WD-40 domains; not an essential gene; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004980","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL035C"}


id: YNL036W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_06611":null,"YNL036W":null},"has_protein_features":false,"name":"NCE103","ortholog_annotations":[{"gene_uniquename":"YNL036W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06611","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL036W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06611","reference_uniquename":"PMID:26896847"}],"product":"Carbonic anhydrase; metalloenzyme that catalyzes CO2 hydration to bicarbonate, which is an important metabolic substrate, and protons; not expressed under conditions of high CO2, such as inside a growing colony, but transcription is induced in response to low CO2 levels, such as on the colony surface in ambient air; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004981","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL036W"}


id: YNL037C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"IDH1","product":"Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase; complex catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle","secondary_identifier":"SGD:S000004982","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL037C"}


id: YNL038W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02804":null,"YNL038W":null},"has_protein_features":false,"name":"GPI15","ortholog_annotations":[{"gene_uniquename":"YNL038W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02804","reference_uniquename":"PMID:29761456"}],"product":"Protein involved in the synthesis of GlcNAc-PI; GlcNAc-PI is the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-H protein; GlcNAc-PI stands for N-acetylglucosaminyl phosphatidylinositol","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004983","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL038W"}


id: YNL039W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03007":null,"YNL039W":null},"has_protein_features":false,"name":"BDP1","ortholog_annotations":[{"gene_uniquename":"YNL039W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03007","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL039W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03007","reference_uniquename":"PMID:26896847"}],"product":"Essential subunit of RNA polymerase III transcription factor (TFIIIB); TFIIIB is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004984","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL039W"}


id: YNL040C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; deletion confers sensitivity to osmotic stress","secondary_identifier":"SGD:S000350098","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL040C-A"}


id: YNL040W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Ser-tRNA(Ala) hydrolase; hydrolyzes Ser-mischarged cytoplasmic and mitochondrial tRNAs; regulates translational fidelity based on Ala- and Thr-to-Ser misincorporation in the null mutant; trans-editing factor for alanyl- and threonyl-tRNA synthetases and seryl-tRNA synthetase (SerRS) via hydrolysis; null mutant displays decreased translation rate and increased readthrough of premature stop codons; (GFP)-fusion protein localizes to the cytoplasm; homologous to human trans-editing factor AARSD","secondary_identifier":"SGD:S000004985","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL040W"}


id: YNL041C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03158":null,"YNL041C":null},"has_protein_features":false,"name":"COG6","ortholog_annotations":[{"gene_uniquename":"YNL041C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03158","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL041C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03158","reference_uniquename":"PMID:26896847"}],"product":"Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004986","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL041C"}


id: YNL042W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"BOP3","product":"Protein of unknown function; potential Cdc28p substrate; overproduction confers resistance to methylmercury","secondary_identifier":"SGD:S000004987","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL042W"}


id: YNL042W-B
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function","secondary_identifier":"SGD:S000028850","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL042W-B"}


id: YNL043C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YIP3/YNL044W","secondary_identifier":"SGD:S000004988","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL043C"}


id: YNL044W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00767":null,"YNL044W":null},"has_protein_features":false,"name":"YIP3","ortholog_annotations":[{"gene_uniquename":"YNL044W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00767","reference_uniquename":"PMID:29761456"}],"product":"Protein localized to COPII vesicles; proposed to be involved in ER-to-Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p; integral membrane protein that localizes to the ER, the Golgi apparatus, transport vesicles and the peroxisome; two isoforms exist, a full-length Yip3L (Yip3 Long) and a shorter peroxisomal matrix isoform Yip3S (Yip3 Short)","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004989","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL044W"}


id: YNL045W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01088":null,"YNL045W":null},"has_protein_features":false,"name":"LAP2","ortholog_annotations":[{"gene_uniquename":"YNL045W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01088","reference_uniquename":"PMID:29761456"}],"product":"Leucyl aminopeptidase yscIV with epoxide hydrolase activity; metalloenzyme containing one zinc atom; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; also known as leukotriene A4 hydrolase","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004990","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL045W"}


id: YNL046W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)","secondary_identifier":"SGD:S000004991","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL046W"}


id: YNL047C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02989":null,"YNL047C":null},"has_protein_features":false,"name":"SLM2","ortholog_annotations":[{"gene_uniquename":"YNL047C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02989","reference_uniquename":"PMID:29761456"}],"product":"Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; TORC2 complex substrate and effector; SLM2 has a paralog, SLM1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004992","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL047C"}


id: YNL048W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00747":null,"YNL048W":null},"has_protein_features":false,"name":"ALG11","ortholog_annotations":[{"gene_uniquename":"YNL048W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00747","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL048W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00747","reference_uniquename":"PMID:26896847"}],"product":"Alpha-1,2-mannosyltransferase; catalyzes sequential addition of the two terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004993","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL048W"}


id: YNL049C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00072":null,"YNL049C":null},"has_protein_features":false,"name":"SFB2","ortholog_annotations":[{"gene_uniquename":"YNL049C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00072","reference_uniquename":"PMID:29761456"}],"product":"Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat; required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sfb3p; SFB2 has a paralog, SEC24, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004994","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL049C"}


id: YNL050C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03020":null,"YNL050C":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YNL050C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03020","reference_uniquename":"PMID:29761456"}],"product":"Putative protein of unknown function; YNL050c is not an essential gene","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004995","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL050C"}


id: YNL051W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02211":null,"YNL051W":null},"has_protein_features":false,"name":"COG5","ortholog_annotations":[{"gene_uniquename":"YNL051W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02211","reference_uniquename":"PMID:29761456"}],"product":"Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004996","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL051W"}


id: YNL052W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01077":null,"YNL052W":null},"has_protein_features":false,"name":"COX5A","ortholog_annotations":[{"gene_uniquename":"YNL052W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01077","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL052W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01077","reference_uniquename":"PMID:26896847"}],"product":"Subunit Va of cytochrome c oxidase; cytochrome c oxidase is the terminal member of the mitochondrial inner membrane electron transport chain; Cox5Ap is predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth; COX5A has a paralog, COX5B, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004997","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL052W"}


id: YNL053W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03263":null,"YNL053W":null},"has_protein_features":false,"name":"MSG5","ortholog_annotations":[{"gene_uniquename":"YNL053W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03263","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL053W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03263","reference_uniquename":"PMID:26896847"}],"product":"Dual-specificity protein phosphatase; maintains low levels of both basal and induced cell integrity pathway signaling by dephosphorylation of the Slt2p MAPK; reciprocally regulated by Slt2p through phosphorylation; minor role with Ptp2p in the adaptive response to pheromone through the dephosphorylation of the Fus3p MAPK with major contribution by Ptp3p; inhibits the nuclear accumulation of Fus3p; two isoforms exist as the result of alternative translation initiation starts","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000004998","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL053W"}


id: YNL054W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02665":null,"YNL054W":null},"has_protein_features":false,"name":"VAC7","ortholog_annotations":[{"gene_uniquename":"YNL054W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02665","reference_uniquename":"PMID:29761456"}],"product":"Integral vacuolar membrane protein; involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock; targeted to vacuole via AP-3 pathway","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000004999","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL054W"}


id: YNL055C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00048":null,"YNL055C":null},"has_protein_features":false,"name":"POR1","ortholog_annotations":[{"gene_uniquename":"YNL055C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00048","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL055C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00048","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial porin and phospholipid scramblase; voltage-dependent anion channel in the outer mitochondrial membrane required for maintenance of mitochondrial osmotic stability and membrane permeability; scramblase involved in mitochondrial transbilayer translocation of phospholipids; ubiquinone binding protein; couples glutathione pools of the intermembrane space and the cytosol; phosphorylated; protein abundance increases in response to DNA replication stress; orthologous to human VDAC1 and 2","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005000","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL055C"}


id: YNL056W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"OCA2","product":"Protein of unknown function; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene","secondary_identifier":"SGD:S000005001","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL056W"}


id: YNL057W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data","secondary_identifier":"SGD:S000005002","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL057W"}


id: YNL058C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to vacuole; not an essential gene; YNL058C has a paralog, PRM5, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005003","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL058C"}


id: YNL059C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03839":null,"YNL059C":null},"has_protein_features":false,"name":"ARP5","ortholog_annotations":[{"gene_uniquename":"YNL059C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03839","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL059C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03839","reference_uniquename":"PMID:26896847"}],"product":"Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes; promotes nucleosome shifts in the 3 prime direction","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005004","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL059C"}


id: YNL061W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02417":null,"YNL061W":null},"has_protein_features":false,"name":"NOP2","ortholog_annotations":[{"gene_uniquename":"YNL061W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02417","reference_uniquename":"PMID:29761456"}],"product":"rRNA m5C methyltransferase; methylates cytosine at position 2870 of 25S rRNA; has an essential function independent of rRNA methylation; contains seven beta-strand methyltransferase motif; essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles; rRNA methylation defect and lethality are functionally complemented by human NOP2, a gene upregulated in cancer","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005005","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL061W"}


id: YNL062C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02637":null,"YNL062C":null},"has_protein_features":false,"name":"GCD10","ortholog_annotations":[{"gene_uniquename":"YNL062C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02637","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL062C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02637","reference_uniquename":"PMID:26896847"}],"product":"Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p; required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005006","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL062C"}


id: YNL063W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00286":null,"YNL063W":null},"has_protein_features":false,"name":"MTQ1","ortholog_annotations":[{"gene_uniquename":"YNL063W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00286","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL063W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00286","reference_uniquename":"PMID:26896847"}],"product":"S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005007","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL063W"}


id: YNL064C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00436":null,"YNL064C":null},"has_protein_features":false,"name":"YDJ1","ortholog_annotations":[{"gene_uniquename":"YNL064C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00436","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL064C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00436","reference_uniquename":"PMID:26896847"}],"product":"Type I HSP40 co-chaperone; regulates HSP90 and HSP70 functions; acts as an adaptor that helps Rsp5p recognize and ubiquitinate misfolded, cytosolic proteins after heat shock; critical for determining cell size at Start as a function of growth rate; involved in protein translocation across membranes; forms cytotoxic amyloidogenic-like structures in vitro; DnaJ family member; chimeric protein in which the human p58IPK J domain replaces the yeast Ydj1p J domain can complement yeast ydj1 mutant","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005008","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL064C"}


id: YNL065W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"AQR1","product":"Plasma membrane transporter of the major facilitator superfamily; involved in the excretion of excess amino acids; member of the 12-spanner drug:H(+) antiporter DHA1 family; confers resistance to short-chain monocarboxylic acids and quinidine; relocalizes from plasma membrane to cytoplasm upon DNA replication stress; AQR1 has a paralog, QDR1, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005009","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL065W"}


id: YNL066W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02649":null,"SJAG_03295":null,"YNL066W":null},"has_protein_features":false,"name":"SUN4","ortholog_annotations":[{"gene_uniquename":"YNL066W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02649","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL066W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02649","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL066W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03295","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL066W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03295","reference_uniquename":"PMID:26896847"}],"product":"Cell wall protein related to glucanases localized in birth scars; possibly involved in cell wall septation; member of the SUN family; SUN4 has a paralog, SIM1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005010","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL066W"}


id: YNL067W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00629":null,"SJAG_00748":null,"YNL067W":null},"has_protein_features":false,"name":"RPL9B","ortholog_annotations":[{"gene_uniquename":"YNL067W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00629","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL067W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00629","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL067W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00748","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL067W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00748","reference_uniquename":"PMID:29761456"}],"product":"Ribosomal 60S subunit protein L9B; homologous to mammalian ribosomal protein L9 and bacterial L6; RPL9B has a paralog, RPL9A, that arose from a single-locus duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005011","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL067W"}


id: YNL067W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data","secondary_identifier":"SGD:S000007623","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL067W-A"}


id: YNL067W-B
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function","secondary_identifier":"SGD:S000028810","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL067W-B"}


id: YNL068C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04813":null,"YNL068C":null},"has_protein_features":false,"name":"FKH2","ortholog_annotations":[{"gene_uniquename":"YNL068C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04813","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL068C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04813","reference_uniquename":"PMID:26896847"}],"product":"Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005012","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL068C"}


id: YNL069C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02207":null,"SJAG_04160":null,"YNL069C":null},"has_protein_features":false,"name":"RPL16B","ortholog_annotations":[{"gene_uniquename":"YNL069C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02207","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL069C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02207","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL069C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02207","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL069C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04160","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL069C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04160","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL069C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04160","reference_uniquename":"PMID:29761456"}],"product":"Ribosomal 60S subunit protein L16B; N-terminally acetylated, binds 5.8 S rRNA; transcriptionally regulated by Rap1p; homologous to mammalian ribosomal protein L13A and bacterial L13; RPL16B has a paralog, RPL16A, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005013","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL069C"}


id: YNL070W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03502":null,"YNL070W":null},"has_protein_features":false,"name":"TOM7","ortholog_annotations":[{"gene_uniquename":"YNL070W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03502","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL070W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03502","reference_uniquename":"PMID:26896847"}],"product":"Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005014","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL070W"}


id: YNL071W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02158":null,"YNL071W":null},"has_protein_features":false,"name":"LAT1","ortholog_annotations":[{"gene_uniquename":"YNL071W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02158","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL071W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02158","reference_uniquename":"PMID:26896847"}],"product":"Dihydrolipoamide acetyltransferase component (E2) of the PDC; the pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA; metabolic longevity factor required for calorie restriction-mediated life span extension","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005015","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL071W"}


id: YNL072W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02039":null,"YNL072W":null},"has_protein_features":false,"name":"RNH201","ortholog_annotations":[{"gene_uniquename":"YNL072W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02039","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL072W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02039","reference_uniquename":"PMID:26896847"}],"product":"Ribonuclease H2 catalytic subunit; removes RNA primers during Okazaki fragment synthesis and errant ribonucleotides misincorporated during DNA replication; role in ribonucleotide excision repair; homolog of RNAse HI; related to human AGS4 which causes Aicardi-Goutieres syndrome","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005016","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL072W"}


id: YNL073W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04409":null,"YNL073W":null},"has_protein_features":false,"name":"MSK1","ortholog_annotations":[{"gene_uniquename":"YNL073W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04409","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL073W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04409","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial lysine-tRNA synthetase; required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria and for aminoacylation of mitochondrially encoded tRNA(Lys)","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005017","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL073W"}


id: YNL074C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"MLF3","product":"Serine-rich protein of unknown function; predicted to be palmitoylated; overproduction suppresses growth inhibition caused by exposure to immunosuppressant leflunomide; MLF3 has a paralog, VHS2, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005018","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL074C"}


id: YNL075W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03252":null,"YNL075W":null},"has_protein_features":false,"name":"IMP4","ortholog_annotations":[{"gene_uniquename":"YNL075W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03252","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL075W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03252","reference_uniquename":"PMID:26896847"}],"product":"Component of the SSU processome; SSU processome is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005019","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL075W"}


id: YNL076W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03319":null,"YNL076W":null},"has_protein_features":false,"name":"MKS1","ortholog_annotations":[{"gene_uniquename":"YNL076W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03319","reference_uniquename":"PMID:29761456"}],"product":"Pleiotropic negative transcriptional regulator; involved in Ras-cAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005020","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL076W"}


id: YNL077W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"APJ1","product":"Hsp40 chaperone with a role in SUMO-mediated protein degradation; works in concert with Hsp70 and Hsp110 (Sse1p) to promote disaggregation of intranuclear protein inclusions; competes with Hsp104 in disaggregation, supporting turnover instead of refolding; member of DnaJ-like family, conserved across eukaryotes; overexpression interferes with propagation of the [Psi+] prion; forms nuclear foci upon DNA replication stress","secondary_identifier":"SGD:S000005021","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL077W"}


id: YNL078W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"NIS1","product":"Protein involved in axial bud site selection; prevents repolarization of cells at previous division sites; recruited with Nba1p to the cell cortex and to cytokinesis remnants (bud scars) by Aim44p and Nap1p where Nba1p prevents Rsr1p-mediated activation of Cdc24p, and therefore Cdc42p activation; acts with Nba1p to establish transient bud scar localization of Rga1p, a Cdc42p GAP; localizes to the nucleus and to cell division site during G2/M, and is then stably recruited to cytokinesis remnants","secondary_identifier":"SGD:S000005022","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL078W"}


id: YNL079C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04887":null,"YNL079C":null},"has_protein_features":false,"name":"TPM1","ortholog_annotations":[{"gene_uniquename":"YNL079C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04887","reference_uniquename":"PMID:29761456"}],"product":"Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently; TPM1 has a paralog, TPM2, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005023","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL079C"}


id: YNL080C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03330":null,"YNL080C":null},"has_protein_features":false,"name":"EOS1","ortholog_annotations":[{"gene_uniquename":"YNL080C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03330","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL080C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03330","reference_uniquename":"PMID:26896847"}],"product":"Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005024","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL080C"}


id: YNL081C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00782":null,"YNL081C":null},"has_protein_features":false,"name":"SWS2","ortholog_annotations":[{"gene_uniquename":"YNL081C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00782","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL081C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00782","reference_uniquename":"PMID:26896847"}],"product":"Component of mitochondrial small ribosomal subunit; similar to E. coli S13 ribosomal protein; participates in controlling sporulation efficiency; localizes to vacuole in response to H2O2; localizes to peroxisomes in glucose-growing cells","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005025","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL081C"}


id: YNL082W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02187":null,"YNL082W":null},"has_protein_features":false,"name":"PMS1","ortholog_annotations":[{"gene_uniquename":"YNL082W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02187","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL082W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02187","reference_uniquename":"PMID:26896847"}],"product":"ATP-binding protein required for mismatch repair; required for both mitosis and meiosis; functions as a heterodimer with Mlh1p; binds double- and single-stranded DNA via its N-terminal domain; required for silencing at the silent mating-type loci and telomeres; similar to E. coli MutL","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005026","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL082W"}


id: YNL083W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00612":null,"YNL083W":null},"has_protein_features":false,"name":"SAL1","ortholog_annotations":[{"gene_uniquename":"YNL083W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00612","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL083W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00612","reference_uniquename":"PMID:26896847"}],"product":"ADP/ATP transporter; member of the Ca2+-binding subfamily of mitochondrial carriers, with two EF-hand motifs; transport activity of either Sal1p or Pet9p is critical for viability; polymorphic in different S. cerevisiae strains","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005027","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL083W"}


id: YNL084C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03465":null,"YNL084C":null},"has_protein_features":false,"name":"END3","ortholog_annotations":[{"gene_uniquename":"YNL084C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03465","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL084C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03465","reference_uniquename":"PMID:26896847"}],"product":"EH domain-containing protein involved in endocytosis; actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005028","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL084C"}


id: YNL085W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00670":null,"YNL085W":null},"has_protein_features":false,"name":"MKT1","ortholog_annotations":[{"gene_uniquename":"YNL085W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00670","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL085W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00670","reference_uniquename":"PMID:26896847"}],"product":"Protein similar to nucleases that forms a complex with Pbp1p; complex may mediate posttranscriptional regulation of HO; involved in propagation of M2 dsRNA satellite of L-A virus; allelic variation affects mitochondrial genome stability, drug resistance, and more; forms cytoplasmic foci upon DNA replication stress; localization to P-bodies under ethanol stress differs between strains","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005029","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL085W"}


id: YNL086W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"SNN1","product":"Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to endosomes","secondary_identifier":"SGD:S000005030","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL086W"}


id: YNL087W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01437":null,"SJAG_04413":null,"SJAG_04417":null,"YNL087W":null},"has_protein_features":false,"name":"TCB2","ortholog_annotations":[{"gene_uniquename":"YNL087W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01437","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL087W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01437","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL087W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04413","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL087W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04413","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL087W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04417","reference_uniquename":"PMID:29761456"}],"product":"Lipid-binding ER tricalbin involved in ER-plasma membrane tethering; one of at least 7 proteins (Ice2p, Ist2p, Scs2/Scs22p, Tcb1-Tcb3p) that affect cER tethering and contact with the plasma membrane (PM); regulates PI4P levels by controlling access of Sac1p to its substrate PI4P in the PM; regulates PM phospholipid homeostasis; contains 3 calcium and lipid binding domains; localizes to the cortical ER, the cell periphery and is enriched in bud membranes; mRNA is targeted to the bud tip","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005031","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL087W"}


id: YNL088W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03567":null,"YNL088W":null},"has_protein_features":false,"name":"TOP2","ortholog_annotations":[{"gene_uniquename":"YNL088W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03567","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL088W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03567","reference_uniquename":"PMID:26896847"}],"product":"Topoisomerase II; relieves torsional strain in DNA by cleaving and re-sealing phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis; required for replication slow zone (RSZ) breakage following Mec1p inactivation; human homolog TOP2A implicated in cancers, and can complement yeast null mutant","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005032","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL088W"}


id: YNL089C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame unlikely to encode a functional protein; almost completely overlaps YNL090W/RHO2 which encodes a small GTPase of the Rho/Rac subfamily of Ras-like proteins","secondary_identifier":"SGD:S000005033","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL089C"}


id: YNL090W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00424":null,"YNL090W":null},"has_protein_features":false,"name":"RHO2","ortholog_annotations":[{"gene_uniquename":"YNL090W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00424","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL090W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00424","reference_uniquename":"PMID:26896847"}],"product":"Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity and in microtubule assembly","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005034","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL090W"}


id: YNL091W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00423":null,"YNL091W":null},"has_protein_features":false,"name":"NST1","ortholog_annotations":[{"gene_uniquename":"YNL091W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00423","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL091W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00423","reference_uniquename":"PMID:26896847"}],"product":"Translational inhibitor and suppressor of proteasome-assembly defects; P-body component that inhibits translation, rescues proteasome base assembly defects and aggregation of regulatory particle subunits during stress when overexpressed; proposed to function to bridge the HOG and pheromone pathways with the cell wall integrity pathway in response to heat stress; interacts physically and genetically with splicing factor MSL1; large, highly-charge protein containing many disordered regions","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005035","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL091W"}


id: YNL092W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03087":null,"YNL092W":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YNL092W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03087","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL092W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03087","reference_uniquename":"PMID:26896847"}],"product":"S-adenosylmethionine-dependent protein methyltransferase; capable of automethylation; member of the seven beta-strand family; YNL092W is not an essential gene","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005036","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL092W"}


id: YNL093W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01379":null,"YNL093W":null},"has_protein_features":false,"name":"YPT53","ortholog_annotations":[{"gene_uniquename":"YNL093W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01379","reference_uniquename":"PMID:29761456"}],"product":"Stress-induced Rab family GTPase; required for vacuolar protein sorting and endocytosis; involved in ionic stress tolerance; similar to Vps21p and Ypt52p; functional homolog of Vps21p; mammalian Rab5 homolog; YPT53 has a paralog, VPS21, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005037","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL093W"}


id: YNL094W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00920":null,"YNL094W":null},"has_protein_features":false,"name":"APP1","ortholog_annotations":[{"gene_uniquename":"YNL094W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00920","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL094W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00920","reference_uniquename":"PMID:26896847"}],"product":"Phosphatidate phosphatase, converts phosphatidate to diacylglycerol; App1p, Pah1p, Dpp1p, and Lpp1p are responsible for all the phosphatidate phosphatase activity; component of cortical actin patches; interacts with components of endocytic pathway","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005038","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL094W"}


id: YNL095C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; predicted to contain a transmembrane domain; not an essential gene; YNL095C has a paralog, ECM3, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005039","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL095C"}


id: YNL096C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02046":null,"YNL096C":null},"has_protein_features":false,"name":"RPS7B","ortholog_annotations":[{"gene_uniquename":"YNL096C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02046","reference_uniquename":"PMID:29761456"}],"product":"Protein component of the small (40S) ribosomal subunit; interacts with Kti11p; deletion causes hypersensitivity to zymocin; homologous to mammalian ribosomal protein S7, no bacterial homolog; RPS7B has a paralog, RPS7A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005040","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL096C"}


id: YNL097C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03230":null,"SJAG_03628":null,"YNL097C":null},"has_protein_features":false,"name":"PHO23","ortholog_annotations":[{"gene_uniquename":"YNL097C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03230","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL097C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03230","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL097C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03628","reference_uniquename":"PMID:29761456"}],"product":"Component of the Rpd3L histone deacetylase complex; involved in transcriptional regulation of PHO5; affects termination of snoRNAs and cryptic unstable transcripts (CUTs); C-terminus shares significant sequence identity with the human candidate tumor suppressor p33-ING1 and its isoform ING3","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005041","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL097C"}


id: YNL097C-B
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"PLS1","product":"Peroxisomal matrix protein that regulates lysine biosynthesis; localization to peroxisomes upon lysine deprivation is dependent on targeting factor Pex5p and lysine biosynthesis enzyme Lys1p; affects abundance of Lys1p and the lysine biosynthesis pathway","secondary_identifier":"SGD:S000028699","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL097C-B"}


id: YNL097W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene PHO23/YNL097C","secondary_identifier":"SGD:S000028700","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL097W-A"}


id: YNL098C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03453":null,"YNL098C":null},"has_protein_features":false,"name":"RAS2","ortholog_annotations":[{"gene_uniquename":"YNL098C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03453","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL098C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03453","reference_uniquename":"PMID:26896847"}],"product":"GTP-binding protein; regulates nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; activated by increased levels of glycolysis intermediate fructose-1,6-bisphosphate; homolog of mammalian Ras proto-oncogenes; RAS2 has a paralog, RAS1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005042","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL098C"}


id: YNL099C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"OCA1","product":"Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA","secondary_identifier":"SGD:S000005043","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL099C"}


id: YNL100W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02501":null,"YNL100W":null},"has_protein_features":false,"name":"MIC27","ortholog_annotations":[{"gene_uniquename":"YNL100W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02501","reference_uniquename":"PMID:29761456"}],"product":"Component of the MICOS complex; MICOS (formerly MINOS or MitOS), a mitochondrial inner membrane complex that extends into the intermembrane space with a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; forms a subcomplex with Mic10p and Mic12p whose assembly and stability requires cardiolipin; orthologous to human APOO and APOOL","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005044","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL100W"}


id: YNL101W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03400":null,"YNL101W":null},"has_protein_features":false,"name":"AVT4","ortholog_annotations":[{"gene_uniquename":"YNL101W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03400","reference_uniquename":"PMID:29761456"}],"product":"Vacuolar transporter; exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs)","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005045","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL101W"}


id: YNL102W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05239":null,"YNL102W":null},"has_protein_features":false,"name":"POL1","ortholog_annotations":[{"gene_uniquename":"YNL102W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05239","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL102W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05239","reference_uniquename":"PMID:26896847"}],"product":"Catalytic subunit of the DNA polymerase I alpha-primase complex; required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis; H3-H4 histone chaperone, downstream of Pol32p, involved in the transfer of parental histones to the lagging strand during DNA replication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005046","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL102W"}


id: YNL103W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04749":null,"YNL103W":null},"has_protein_features":false,"name":"MET4","ortholog_annotations":[{"gene_uniquename":"YNL103W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04749","reference_uniquename":"PMID:29761456"}],"product":"Leucine-zipper transcriptional activator; responsible for regulation of sulfur amino acid pathway; requires different combinations of auxiliary factors Cbf1p, Met28p, Met31p and Met32p; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; can be ubiquitinated by ubiquitin ligase SCF-Met30p, is either degraded or maintained in an inactive state; regulates degradation of its own DNA-binding cofactors by targeting them to SCF-Met30p","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005047","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL103W"}


id: YNL103W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MET4/YNL104C","secondary_identifier":"SGD:S000028701","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL103W-A"}


id: YNL104C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02841":null,"YNL104C":null},"has_protein_features":false,"name":"LEU4","ortholog_annotations":[{"gene_uniquename":"YNL104C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02841","reference_uniquename":"PMID:29761456"}],"product":"Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway; LEU4 has a paralog, LEU9, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005048","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL104C"}


id: YNL105W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"RRT16","product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified gene INP52; identified in a screen for mutants with decreased levels of rDNA transcription","secondary_identifier":"SGD:S000005049","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL105W"}


id: YNL106C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00063":null,"SJAG_03375":null,"YNL106C":null},"has_protein_features":false,"name":"INP52","ortholog_annotations":[{"gene_uniquename":"YNL106C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00063","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL106C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03375","reference_uniquename":"PMID:29761456"}],"product":"Polyphosphatidylinositol phosphatase; dephosphorylates a number of phosphatidylinositol phosphates (PtdInsPs, PIPs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain; INP52 has a paralog, INP53, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005050","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL106C"}


id: YNL107W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04097":null,"YNL107W":null},"has_protein_features":false,"name":"YAF9","ortholog_annotations":[{"gene_uniquename":"YNL107W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04097","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL107W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04097","reference_uniquename":"PMID:26896847"}],"product":"Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes; may function to antagonize silencing near telomeres; interacts directly with Swc4p; has homology to human leukemogenic protein AF9; contains a YEATS domain","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005051","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL107W"}


id: YNL108C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein phosphatase; similar to prokaryotic phosphotransfer enzymes; null mutant shows alterations in glucose metabolism; GFP-fusion protein localizes to the cytoplasm and nucleus; YNL108C has a paralog, TFC7, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005052","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL108C"}


id: YNL109W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YNL108C","secondary_identifier":"SGD:S000005053","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL109W"}


id: YNL110C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00949":null,"SJAG_02952":null,"YNL110C":null},"has_protein_features":false,"name":"NOP15","ortholog_annotations":[{"gene_uniquename":"YNL110C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00949","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL110C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00949","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL110C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02952","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL110C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02952","reference_uniquename":"PMID:26896847"}],"product":"Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005054","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL110C"}


id: YNL111C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03929":null,"SJAG_04217":null,"YNL111C":null},"has_protein_features":false,"name":"CYB5","ortholog_annotations":[{"gene_uniquename":"YNL111C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03929","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL111C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03929","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL111C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04217","reference_uniquename":"PMID:29761456"}],"product":"Cytochrome b5; involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005055","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL111C"}


id: YNL112W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05276":null,"YNL112W":null},"has_protein_features":false,"name":"DBP2","ortholog_annotations":[{"gene_uniquename":"YNL112W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05276","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL112W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05276","reference_uniquename":"PMID:26896847"}],"product":"ATP-dependent RNA helicase of the DEAD-box protein family; strong preference for dsRNA; remodels RNA-protein complex (RNP) to facilitate efficient transcription termination; required for assembly of Yra1p, Nab2p and Mex67p onto mRNA and formation of nuclear mRNP; involved in mRNA decay and rRNA processing; may be involved in suppression of transcription from cryptic initiation sites; promotes Mex67p-mediated nuclear export of mRNA by facilitating annealing with antisense RNAs to create dsRNAs","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005056","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL112W"}


id: YNL113W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00731":null,"YNL113W":null},"has_protein_features":false,"name":"RPC19","ortholog_annotations":[{"gene_uniquename":"YNL113W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00731","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL113W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00731","reference_uniquename":"PMID:26896847"}],"product":"RNA polymerase subunit AC19; common to RNA polymerases I and III","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005057","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL113W"}


id: YNL114C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RPC19/YNL113W, an RNA polymerase subunit","secondary_identifier":"SGD:S000005058","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL114C"}


id: YNL115C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01795":null,"YNL115C":null},"has_protein_features":false,"ortholog_annotations":[{"gene_uniquename":"YNL115C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01795","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL115C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01795","reference_uniquename":"PMID:26896847"}],"product":"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL115C is not an essential gene","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005059","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL115C"}


id: YNL116W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02169":null,"YNL116W":null},"has_protein_features":false,"name":"DMA2","ortholog_annotations":[{"gene_uniquename":"YNL116W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02169","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL116W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02169","reference_uniquename":"PMID:26896847"}],"product":"Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005060","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL116W"}


id: YNL117W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"MLS1","product":"Malate synthase, enzyme of the glyoxylate cycle; involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth on oleic acid, otherwise cytosolic; can accept butyryl-CoA as acyl-CoA donor in addition to traditional substrate acetyl-CoA","secondary_identifier":"SGD:S000005061","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL117W"}


id: YNL118C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05010":null,"YNL118C":null},"has_protein_features":false,"name":"DCP2","ortholog_annotations":[{"gene_uniquename":"YNL118C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05010","reference_uniquename":"PMID:29761456"}],"product":"Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex; removes 5' cap structure from mRNAs prior to their degradation; also enters nucleus and positively regulates transcription initiation; nudix hydrolase family member; forms cytoplasmic foci upon DNA replication stress; human homolog DCP2 complements yeast dcp2 thermosensitive mutant","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005062","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL118C"}


id: YNL119W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01302":null,"YNL119W":null},"has_protein_features":false,"name":"NCS2","ortholog_annotations":[{"gene_uniquename":"YNL119W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01302","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL119W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01302","reference_uniquename":"PMID:26896847"}],"product":"Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs; required for the thiolation of uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005063","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL119W"}


id: YNL120C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; deletion enhances replication of Brome mosaic virus in S. cerevisiae, but likely due to effects on the overlapping gene","secondary_identifier":"SGD:S000005064","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL120C"}


id: YNL121C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04996":null,"YNL121C":null},"has_protein_features":false,"name":"TOM70","ortholog_annotations":[{"gene_uniquename":"YNL121C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04996","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL121C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04996","reference_uniquename":"PMID:26896847"}],"product":"Component of the TOM (translocase of outer membrane) complex; involved in the recognition and initial import steps for all mitochondrially-directed proteins, acting as a receptor for incoming precursor proteins; moonlighting role as a transcriptional regulator of mitochondrial proteins; age-dependent reduction in Tom70p results in mitochondrial dysfunction, a hallmark of aging; localizes to mitochondria–ER contact sites; TOM70 has a paralog, TOM71, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005065","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL121C"}


id: YNL122C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_07009":null,"YNL122C":null},"has_protein_features":false,"name":"MRP35","ortholog_annotations":[{"gene_uniquename":"YNL122C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_07009","reference_uniquename":"PMID:29761456"}],"product":"Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L35 and human MRPL35 ribosomal proteins","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005066","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL122C"}


id: YNL123W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00737":null,"SJAG_03258":null,"YNL123W":null},"has_protein_features":false,"name":"NMA111","ortholog_annotations":[{"gene_uniquename":"YNL123W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00737","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL123W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00737","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL123W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03258","reference_uniquename":"PMID:29761456"}],"product":"Serine protease and general molecular chaperone; cleaves Roq1p, which modifies the substrate specificity of the Ubr1p Ub-ligase, promoting the stress-induced homeostatically-regulated protein degradation (SHRED) of misfolded and native ER-membrane and cytosolic proteins; chaperone activity involved in the heat stress response; promotes apoptosis through proteolysis of Bir1p; role in lipid homeostasis; mammalian Omi/HtrA2 serine protease family member","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005067","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL123W"}


id: YNL124W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03125":null,"YNL124W":null},"has_protein_features":false,"name":"NAF1","ortholog_annotations":[{"gene_uniquename":"YNL124W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03125","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL124W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03125","reference_uniquename":"PMID:26896847"}],"product":"RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005068","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL124W"}


id: YNL125C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ESBP6","product":"Protein with similarity to monocarboxylate permeases; appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane","secondary_identifier":"SGD:S000005069","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL125C"}


id: YNL126W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02609":null,"YNL126W":null},"has_protein_features":false,"name":"SPC98","ortholog_annotations":[{"gene_uniquename":"YNL126W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02609","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL126W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02609","reference_uniquename":"PMID:26896847"}],"product":"Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005070","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL126W"}


id: YNL127W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03508":null,"YNL127W":null},"has_protein_features":false,"name":"FAR11","ortholog_annotations":[{"gene_uniquename":"YNL127W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03508","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL127W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03508","reference_uniquename":"PMID:26896847"}],"product":"Protein involved in recovery from cell cycle arrest; acts in response to pheromone; also involved in regulation of intra-S DNA damage checkpoint and autophagy; is essential for dephosphorylation of Atg13p; interacts with Far3p, Far7p, Far8p, Far9p, Far10p and with the phosphatases Pph21p, Pph22p and Pph3p; has similarity to the N- and C-termini of N. crassa HAM-2; similar to human Fam40A and Fam40B","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005071","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL127W"}


id: YNL128W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03131":null,"YNL128W":null},"has_protein_features":false,"name":"TEP1","ortholog_annotations":[{"gene_uniquename":"YNL128W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03131","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL128W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03131","reference_uniquename":"PMID:26896847"}],"product":"PTEN homolog with no demonstrated inositol lipid phosphatase activity; plays a role in normal sporulation; homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and fission yeast ptn1","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005072","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL128W"}


id: YNL129W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04693":null,"YNL129W":null},"has_protein_features":false,"name":"NRK1","ortholog_annotations":[{"gene_uniquename":"YNL129W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04693","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL129W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04693","reference_uniquename":"PMID:26896847"}],"product":"Nicotinamide riboside kinase; catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005073","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL129W"}


id: YNL130C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04319":null,"YNL130C":null},"has_protein_features":false,"name":"CPT1","ortholog_annotations":[{"gene_uniquename":"YNL130C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04319","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL130C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04319","reference_uniquename":"PMID:26896847"}],"product":"Cholinephosphotransferase; required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription; CPT1 has a paralog, EPT1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005074","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL130C"}


id: YNL130C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"DGR1","product":"Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose","secondary_identifier":"SGD:S000028579","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL130C-A"}


id: YNL131W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03415":null,"YNL131W":null},"has_protein_features":false,"name":"TOM22","ortholog_annotations":[{"gene_uniquename":"YNL131W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03415","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL131W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03415","reference_uniquename":"PMID:26896847"}],"product":"Component of the TOM (Translocase of Outer Membrane) complex; responsible for initial import of mitochondrially directed proteins; mediates interaction between TOM and TIM complexes and acts as receptor for precursor proteins; implicated in mitochondrial accumulation of amyloid beta peptides via direct interaction with amyloid beta peptide residues 25-42 followed by transfer to Tom40p and transport through the TOM channel","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005075","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL131W"}


id: YNL132W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01877":null,"YNL132W":null},"has_protein_features":false,"name":"KRE33","ortholog_annotations":[{"gene_uniquename":"YNL132W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01877","reference_uniquename":"PMID:29761456"}],"product":"Acetyltransferase required for biogenesis of small ribosomal subunit; conserved 18S rRNA cytosine acetyltransferase that modifies tRNAs assisted by adaptor Tan1p; responsible for incorporation of N4-acetylcytidine into mRNAs; human homolog NAT10 implicated in several types of cancer and premature aging","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005076","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL132W"}


id: YNL133C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"FYV6","product":"Protein of unknown function; required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining","secondary_identifier":"SGD:S000005077","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL133C"}


id: YNL134C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"NADH-dependent aldehyde reductase; involved in detoxification of furfural; expression is up-regulated in the presence of furfural and 5-hydroxymethylfurfural, which are compounds generated during lignocellulosic biomass pre-treatment; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress","secondary_identifier":"SGD:S000005078","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL134C"}


id: YNL135C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04155":null,"YNL135C":null},"has_protein_features":false,"name":"FPR1","ortholog_annotations":[{"gene_uniquename":"YNL135C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04155","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL135C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04155","reference_uniquename":"PMID:26896847"}],"product":"Peptidyl-prolyl cis-trans isomerase (PPIase); binds to FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function; associates with promoters of ribosomal protein genes; acts as chaperone to prevent protein aggregation; N-terminally propionylated in vivo; mutation is functionally complemented by human FKBP1A","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005079","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL135C"}


id: YNL136W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04793":null,"YNL136W":null},"has_protein_features":false,"name":"EAF7","ortholog_annotations":[{"gene_uniquename":"YNL136W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04793","reference_uniquename":"PMID:29761456"}],"product":"Subunit of the NuA4 histone acetyltransferase complex; NuA4 acetylates the N-terminal tails of histones H4 and H2A","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005080","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL136W"}


id: YNL137C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00889":null,"YNL137C":null},"has_protein_features":false,"name":"NAM9","ortholog_annotations":[{"gene_uniquename":"YNL137C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00889","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL137C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00889","reference_uniquename":"PMID:26896847"}],"product":"Mitochondrial ribosomal component of the small subunit","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005081","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL137C"}


id: YNL138W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_01754":null,"YNL138W":null},"has_protein_features":false,"name":"SRV2","ortholog_annotations":[{"gene_uniquename":"YNL138W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01754","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL138W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01754","reference_uniquename":"PMID:26896847"}],"product":"Cyclase-associated protein, CAP; N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005082","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL138W"}


id: YNL138W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05208":null,"YNL138W-A":null},"has_protein_features":false,"name":"YSF3","ortholog_annotations":[{"gene_uniquename":"YNL138W-A","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05208","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL138W-A","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05208","reference_uniquename":"PMID:26896847"}],"product":"Component of the SF3b subcomplex of the U2 snRNP; essential protein required for splicing and for assembly of SF3b","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000028509","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL138W-A"}


id: YNL139C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00992":null,"YNL139C":null},"has_protein_features":false,"name":"THO2","ortholog_annotations":[{"gene_uniquename":"YNL139C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00992","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL139C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00992","reference_uniquename":"PMID:26896847"}],"product":"Subunit of the THO complex; THO is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005083","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL139C"}


id: YNL140C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; expressed at both mRNA and protein levels; partially overlaps THO2/YNL139C","secondary_identifier":"SGD:S000005084","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL140C"}


id: YNL141W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"AAH1","product":"Adenine deaminase (adenine aminohydrolase); converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome","secondary_identifier":"SGD:S000005085","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL141W"}


id: YNL142W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04136":null,"YNL142W":null},"has_protein_features":false,"name":"MEP2","ortholog_annotations":[{"gene_uniquename":"YNL142W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04136","reference_uniquename":"PMID:29761456"}],"product":"Ammonium permease involved in regulation of pseudohyphal growth; belongs to Mep-Amt-Rh family of well-conserved ammonium (NH4+) transporters that includes human Rh factors; expression is under nitrogen catabolite repression regulation; activity is controlled by phospho-silencing; phosphorylation of Mep2 mediated by Npr1; dephosphorylation involves Psr1p and Psr2p; Twin-His motif ensures transport specificity","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005086","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL142W"}


id: YNL143C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; expressed at both mRNA and protein levels","secondary_identifier":"SGD:S000005087","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL143C"}


id: YNL144C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; contains a PH domain and binds phosphatidylinositols and phosphatidylethanolamine in a large-scale study; YNL144C has a paralog, YHR131C, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005088","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL144C"}


id: YNL144W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YNL144C","secondary_identifier":"SGD:S000028702","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL144W-A"}


id: YNL145W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"MFA2","product":"Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1","secondary_identifier":"SGD:S000005089","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL145W"}


id: YNL146C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function","secondary_identifier":"SGD:S000028851","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL146C-A"}


id: YNL146W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNL146W is not an essential gene","secondary_identifier":"SGD:S000005090","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL146W"}


id: YNL147W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_05240":null,"YNL147W":null},"has_protein_features":false,"name":"LSM7","ortholog_annotations":[{"gene_uniquename":"YNL147W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05240","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL147W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_05240","reference_uniquename":"PMID:26896847"}],"product":"Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005091","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL147W"}


id: YNL148C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02040":null,"YNL148C":null},"has_protein_features":false,"name":"ALF1","ortholog_annotations":[{"gene_uniquename":"YNL148C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02040","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL148C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02040","reference_uniquename":"PMID:26896847"}],"product":"Alpha-tubulin folding protein; similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005092","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL148C"}


id: YNL149C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00919":null,"YNL149C":null},"has_protein_features":false,"name":"PGA2","ortholog_annotations":[{"gene_uniquename":"YNL149C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00919","reference_uniquename":"PMID:29761456"}],"product":"Essential protein required for maturation of Gas1p and Pho8p; involved in protein trafficking; GFP-fusion protein localizes to the ER and YFP-fusion protein to the nuclear envelope-ER network; null mutants have a cell separation defect","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005093","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL149C"}


id: YNL150W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; extensive overlap with PGA2/YNL149C, an uncharacterized gene with a proposed role in protein trafficking","secondary_identifier":"SGD:S000005094","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL150W"}


id: YNL151C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04161":null,"YNL151C":null},"has_protein_features":false,"name":"RPC31","ortholog_annotations":[{"gene_uniquename":"YNL151C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04161","reference_uniquename":"PMID:29761456"}],"product":"RNA polymerase III subunit C31","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005095","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL151C"}


id: YNL152W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00268":null,"YNL152W":null},"has_protein_features":false,"name":"INN1","ortholog_annotations":[{"gene_uniquename":"YNL152W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00268","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL152W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00268","reference_uniquename":"PMID:26896847"}],"product":"Essential protein that associates with contractile actomyosin ring; required for ingression of the plasma membrane into the bud neck during cytokinesis; C2 domain, a membrane targeting module, is required for function; activates chitin synthase activity of Chs2p during cytokinesis","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005096","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL152W"}


id: YNL153C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00524":null,"YNL153C":null},"has_protein_features":false,"name":"GIM3","ortholog_annotations":[{"gene_uniquename":"YNL153C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00524","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL153C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00524","reference_uniquename":"PMID:26896847"}],"product":"Subunit of the heterohexameric cochaperone prefoldin complex; prefoldin binds specifically to cytosolic chaperonin and transfers target proteins to it; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005097","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL153C"}


id: YNL154C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00402":null,"SJAG_01373":null,"SJAG_03987":null,"YNL154C":null},"has_protein_features":false,"name":"YCK2","ortholog_annotations":[{"gene_uniquename":"YNL154C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00402","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL154C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01373","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL154C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_01373","reference_uniquename":"PMID:26896847"},{"gene_uniquename":"YNL154C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03987","reference_uniquename":"PMID:29761456"}],"product":"Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005098","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL154C"}


id: YNL155C-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Protein of unknown function; well conserved across Saccharomyces species; added to genome annotation based on proteomic, translation, and evolutionary evidence","secondary_identifier":"SGD:S000350099","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL155C-A"}


id: YNL155W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"CUZ1","product":"Protein with a role in the ubiquitin-proteasome pathway; interacts with ubiquitinated protein, Cdc48p and the proteasomal regulatory particle; may protect cells from trivalent metalloid induced proteotoxicity; contains a PACE promoter element and is co-regulated with proteasome subunit genes; AN1-type zinc finger protein, with DHHC and ubiquitin-like domains (UBL); ortholog of ZFAND1, a human gene linked to cancer; protein abundance increases under DNA replication stress","secondary_identifier":"SGD:S000005099","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL155W"}


id: YNL156C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"NSG2","product":"Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins; NSG2 has a paralog, NSG1, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005100","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL156C"}


id: YNL157W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_03309":null,"YNL157W":null},"has_protein_features":false,"name":"IGO1","ortholog_annotations":[{"gene_uniquename":"YNL157W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03309","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL157W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_03309","reference_uniquename":"PMID:26896847"}],"product":"Protein required for initiation of the G0 program; prevents degradation of nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway; phosphorylation (S63) by Rim15p increases interaction with and inhibition of PP2A-Cdc55 for timely mitotic progression; can also activate PP2A-Cdc55 complexes and influence Cdc55p localization along with Igo2p; GFP protein localizes to the cytoplasm and nucleus; IGO1 has a paralog, IGO2, that arose from the whole genome duplication","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005101","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL157W"}


id: YNL158W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_06425":null,"YNL158W":null},"has_protein_features":false,"name":"PGA1","ortholog_annotations":[{"gene_uniquename":"YNL158W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_06425","reference_uniquename":"PMID:29761456"}],"product":"Essential component of GPI-mannosyltransferase II; complex is responsible for second mannose addition to GPI precursors as a partner of Gpi18p; required for maturation of Gas1p and Pho8p; has synthetic genetic interactions with secretory pathway genes","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005102","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL158W"}


id: YNL159C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"ASI2","product":"Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and inner for ubiquitin-mediated degradation; acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids","secondary_identifier":"SGD:S000005103","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL159C"}


id: YNL160W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"YGP1","product":"Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; protein demonstrates amyloid properties in vivo; YGP1 has a paralog, SPS100, that arose from the whole genome duplication","secondary_identifier":"SGD:S000005104","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL160W"}


id: YNL161W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_00661":null,"YNL161W":null},"has_protein_features":false,"name":"CBK1","ortholog_annotations":[{"gene_uniquename":"YNL161W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00661","reference_uniquename":"PMID:29761456"},{"gene_uniquename":"YNL161W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_00661","reference_uniquename":"PMID:26896847"}],"product":"Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress","references_by_uniquename":{"PMID:26896847":null,"PMID:29761456":null},"secondary_identifier":"SGD:S000005105","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL161W"}


id: YNL162W
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_04626":null,"YNL162W":null},"has_protein_features":false,"name":"RPL42A","ortholog_annotations":[{"gene_uniquename":"YNL162W","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_04626","reference_uniquename":"PMID:29761456"}],"product":"Ribosomal 60S subunit protein L42A; homologous to mammalian ribosomal protein L36A, no bacterial homolog; RPL42A has a paralog, RPL42B, that arose from the whole genome duplication","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005106","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL162W"}


id: YNL162W-A
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"product":"Putative protein of unknown function; identified by homology","secondary_identifier":"SGD:S000007624","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL162W-A"}


id: YNL163C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"genes_by_uniquename":{"SJAG_02171":null,"YNL163C":null},"has_protein_features":false,"name":"RIA1","ortholog_annotations":[{"gene_uniquename":"YNL163C","ortholog_taxonid":4897,"ortholog_uniquename":"SJAG_02171","reference_uniquename":"PMID:29761456"}],"product":"Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis; with Sdo1p, a guanine nucleotide exchange factor (GEF), promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; required for quality control check of newly made large ribosomal subunits before they are released into the pool of translating ribosomes","references_by_uniquename":{"PMID:29761456":null},"secondary_identifier":"SGD:S000005107","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL163C"}


id: YNL164C
data:
  {"cv_annotations":{},"deletion_viability":"unknown","feature_so_termid":"SO:0000704","feature_type":"gene","flags":["not_load_organism"],"has_protein_features":false,"name":"IBD2","product":"Component of the BUB2-dependent spindle checkpoint pathway; interacts with Bfa1p and functions upstream of Bub2p and Bfa1p","secondary_identifier":"SGD:S000005108","taxonid":4932,"taxonomic_distribution":"not curated","transcript_so_termid":null,"uniquename":"YNL164C"}


