# terms

id: GO:0031901
data:
  {"annotated_genes":["SJAG_01112","SJAG_00314","SJAG_01379"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[95091,98903,111588],"is_not":false,"summary":null,"term":"GO:0031901"}]},"cv_name":"cellular_component","definition":"The lipid bilayer surrounding an early endosome.","definition_xrefs":["GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endosome membrane","termid":"GO:0010008"},{"relation_name":"part_of","term_name":"early endosome","termid":"GO:0005769"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00314":null,"SJAG_01112":null,"SJAG_01379":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005768"},{"rel_name":"part_of","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0031410","GO:0005575","GO:0005737","GO:0005768"],"is_obsolete":false,"name":"early endosome membrane","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0031901","terms_by_termid":{"GO:0031901":null}}


id: PBO:0033830
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Overexpression causing Deoxyglucose Resistance","termid":"PBO:0033830"}


id: PBO:0075122
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 172","termid":"PBO:0075122"}


id: GO:0106196
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the translocation of inorganic anions linked to the hydrolysis of a nucleoside triphosphate.","definition_xrefs":["GOC:hjd"],"gene_count":0,"genotype_count":0,"name":"obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a nucleoside triphosphate (obsolete GO:0106196)","termid":"GO:0106196"}


id: PBO:0056951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 17","termid":"PBO:0056951"}


id: PATO:0001651
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A resistance to a stimulus which is relatively low.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"resistant to","termid":"PATO:0001178"},{"relation_name":"is_a","term_name":"decreased object quality","termid":"PATO:0002303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased resistance to","synonyms":[{"name":"decreased resistance","type":"exact"},{"name":"low resistance to","type":"exact"}],"termid":"PATO:0001651"}


id: PBO:0062325
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 6 subfamily C member 7 pseudogene","termid":"PBO:0062325"}


id: PBO:0030445
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cell_separation_after_cytokinesis","termid":"PBO:0030445"}


id: GO:0038038
data:
  {"annotated_genes":["SJAG_01978"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[87348],"is_not":false,"summary":null,"term":"GO:0038038"}]},"cv_name":"cellular_component","definition":"A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.","definition_xrefs":["PMID:16670762","GOC:al","PMID:10713101","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor dimeric complex","termid":"GO:0038037"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01978":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005886","GO:0032991"],"is_obsolete":false,"name":"G protein-coupled receptor homodimeric complex","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"G-protein coupled receptor homodimer","type":"exact"},{"name":"G-protein coupled receptor homodimeric complex","type":"exact"},{"name":"GPCR homodimer","type":"exact"}],"termid":"GO:0038038","terms_by_termid":{"GO:0038038":null}}


id: PBO:0087665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and inner for ubiquitin-mediated degradation; acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids","termid":"PBO:0087665"}


id: PBO:0076098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syntaxin 4","termid":"PBO:0076098"}


id: MONDO:0007974
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal dominant condition caused by mutation(s) in the MBD5 gene, encoding methyl-CpG-binding domain protein 5. It is characterized by severe developmental and cognitive delay, short stature, craniofacial dysmorphism, and seizures.","definition_xrefs":["NCIT:C141424"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intellectual disability, autosomal dominant","termid":"MONDO:0100172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"intellectual disability, autosomal dominant 1","secondary_identifiers":["MEDGEN:409857","MESH:C566947","GARD:18623","OMIM:156200","UMLS:C1969562","DOID:0070031"],"synonyms":[{"name":"MBD5 autosomal dominant non-syndromic intellectual disability","type":"exact"},{"name":"MRD1","type":"exact"},{"name":"autosomal dominant intellectual disability 1","type":"exact"},{"name":"autosomal dominant mental retardation 1","type":"exact"},{"name":"autosomal dominant non-syndromic intellectual disability 1","type":"related"},{"name":"autosomal dominant non-syndromic intellectual disability caused by mutation in MBD5","type":"exact"},{"name":"chromosome 2Q23.1 deletion syndrome","type":"related"},{"name":"intellectual disability, autosomal dominant 1","type":"exact"},{"name":"intellectual disability, autosomal dominant type 1","type":"exact"},{"name":"mental retardation, autosomal dominant 1","type":"related"},{"name":"mental retardation, autosomal dominant type 1","type":"exact"}],"termid":"MONDO:0007974","xrefs":{"Monarch":{"xref_id":"0007974"}}}


id: PBO:0079915
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquinol-cytochrome c reductase hinge protein like","termid":"PBO:0079915"}


id: PBO:0027893
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-incomplete_mitotic_sister_chromatid_segregation,_with_unseparated_DNA_and_centromeric_DNA_dissociated_from_spindle","termid":"PBO:0027893"}


id: PBO:0045093
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"distal-less homeobox 4","termid":"PBO:0045093"}


id: PBO:0059772
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO3 pseudogene 46","termid":"PBO:0059772"}


id: GO:0035506
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity.","definition_xrefs":["GOC:bf","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of myosin light chain kinase activity (obsolete GO:0035506)","termid":"GO:0035506"}


id: PBO:0046934
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 50 member B","termid":"PBO:0046934"}


id: FYPO:0005259
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a population reaches stationary phase at, and maintains, a higher cell density than wild type.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"increased cell density in stationary phase","termid":"FYPO:0005259"}


id: GO:0032172
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.","definition_xrefs":["PMID:16151244","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"septin ring","termid":"GO:0005940"},{"relation_name":"part_of","term_name":"germ tube","termid":"GO:0032179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005938"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005938","GO:0005575"],"is_obsolete":false,"name":"germ tube septin ring","termid":"GO:0032172"}


id: PR:O94647
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppk24 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94647"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine-protein kinase ppk24, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC21.07c","synonyms":[{"name":"Spom972h-ppk24","type":"exact"},{"name":"meiotically up-regulated gene 29 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94647"}


id: PBO:0048545
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glial fibrillary acidic protein","termid":"PBO:0048545"}


id: PBO:0038815
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADAM metallopeptidase domain 20 pseudogene 2","termid":"PBO:0038815"}


id: GO:0000489
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maturation of SSU-rRNA","termid":"GO:0030490"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0042254"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0042254","GO:0044085"],"is_obsolete":false,"name":"maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)","termid":"GO:0000489"}


id: MONDO:0035740
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acquired hemophilia","termid":"MONDO:0019139"},{"relation_name":"is_a","term_name":"factor XI deficiency","termid":"MONDO:0020587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"acquired factor XI deficiency","secondary_identifiers":["Orphanet:599507","NCIT:C131627","GARD:22411","MEDGEN:1376431","UMLS:C4329257"],"synonyms":[{"name":"aFXI","type":"exact"}],"termid":"MONDO:0035740","xrefs":{"Monarch":{"xref_id":"0035740"}}}


id: PBO:0085568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein expressed during sporulation; SPS2 has a paralog, SPS22, that arose from the whole genome duplication; redundant with Sps22p for organization of the beta-glucan layer of the spore wall; S. pombe ortholog is a spore wall component","termid":"PBO:0085568"}


id: GO:0102684
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-phenylalanine + 2 NADPH + 2 O2 + 2 H+ = (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide.","definition_xrefs":["EC:1.14.14.40","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"L-phenylalanine N-monooxygenase activity","secondary_identifiers":["MetaCyc:RXN-4602","RHEA:33263"],"termid":"GO:0102684"}


id: GO:0015505
data:
  {"annotated_genes":["SJAG_04714"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[87658,94734],"is_not":false,"summary":null,"term":"GO:0015505"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).","definition_xrefs":["GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uracil transmembrane transporter activity","termid":"GO:0015210"},{"relation_name":"is_a","term_name":"nucleobase:monoatomic cation symporter activity","termid":"GO:0015391"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04714":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"uracil:monoatomic cation symporter activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"uracil permease activity","type":"related"},{"name":"uracil:cation symporter activity","type":"broad"}],"termid":"GO:0015505","terms_by_termid":{"GO:0015505":null}}


id: PBO:0029387
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_threonine_phosphorylation_at_Thr-Pro_site_during_cellular_response_to_hydrogen_peroxide","termid":"PBO:0029387"}


id: MONDO:0009032
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cranioectodermal dysplasia (CED) is a rare developmental disorder characterized by congenital skeletal and ectodermal defects associated with dysmorphic features, nephronophthisis, hepatic fibrosis and ocular anomalies (mainly retinitis pigmentosa).","definition_xrefs":["Orphanet:1515"],"direct_ancestors":[{"relation_name":"is_a","term_name":"craniosynostosis syndrome, autosomal recessive","termid":"MONDO:0011679"},{"relation_name":"is_a","term_name":"syndromic craniosynostosis","termid":"MONDO:0015338"},{"relation_name":"is_a","term_name":"short rib-polydactyly syndrome","termid":"MONDO:0015461"},{"relation_name":"is_a","term_name":"inherited renal tubular disease","termid":"MONDO:0015962"},{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240","MONDO:0006025","MONDO:0005497","MONDO:0005093"],"is_obsolete":false,"name":"cranioectodermal dysplasia","secondary_identifiers":["NCIT:C129305","SCTID:254093009","UMLS:C4551571","DOID:0050577","icd11.foundation:1588881145","GARD:359","MEDGEN:1641011","ICD9:756.9","OMIMPS:218330"],"synonyms":[{"name":"CED","type":"exact"},{"name":"Levin syndrome","type":"exact"},{"name":"Sensenbrenner syndrome","type":"exact"},{"name":"cranioectodermal dysplasia","type":"exact"}],"termid":"MONDO:0009032","xrefs":{"Monarch":{"xref_id":"0009032"}}}


id: PR:O43012
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dcd1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O43012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deoxycytidylate deaminase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC2G2.13c","synonyms":[{"name":"Spom972h-dcd1","type":"exact"},{"name":"dCMP deaminase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O43012"}


id: GO:0050605
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.","definition_xrefs":["EC:1.15.1.2","MetaCyc:1.15.1.2-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antioxidant activity","termid":"GO:0016209"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on superoxide radicals as acceptor","termid":"GO:0016721"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"superoxide reductase activity","secondary_identifiers":["RHEA:21324"],"synonyms":[{"name":"desulfoferrodoxin activity","type":"related"},{"name":"neelaredoxin activity","type":"related"},{"name":"rubredoxin:superoxide oxidoreductase activity","type":"related"}],"termid":"GO:0050605"}


id: PBO:0057690
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1279","termid":"PBO:0057690"}


id: PBO:0028316
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_wtf-derived_RNA_level","termid":"PBO:0028316"}


id: GO:0140122
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of Lewy body formation.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of inclusion body assembly","termid":"GO:0090083"},{"relation_name":"regulates","term_name":"Lewy body formation","termid":"GO:0140121"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"regulation of Lewy body formation","termid":"GO:0140122"}


id: PBO:0049009
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucose-6-phosphate isomerase","termid":"PBO:0049009"}


id: MOD:01752
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-130 reporter+balance group.","definition_xrefs":["Unimod:737"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"cysTMT6plex-130 reporter+balance reagent cysteine disulfide","termid":"MOD:01827"},{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent acylated residue","termid":"MOD:01715"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-130 reporter+balance reagent acylated residue","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01752"}


id: PBO:0045017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"divergent protein kinase domain 1B","termid":"PBO:0045017"}


id: PBO:0003649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Golgi transport complex subunit Cog8 (predicted)","termid":"PBO:0003649"}


id: PBO:0036540
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DENN domain Rab GDP-GTP exchange factor, unknown biological role (predicted)","termid":"PBO:0036540"}


id: GO:1901224
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the non-canonical NF-kappaB cascade.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of non-canonical NF-kappaB signal transduction","termid":"GO:1901222"},{"relation_name":"is_a","term_name":"positive regulation of intracellular signal transduction","termid":"GO:1902533"},{"relation_name":"positively_regulates","term_name":"non-canonical NF-kappaB signal transduction","termid":"GO:0038061"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of non-canonical NF-kappaB signal transduction","secondary_identifiers":["GO:0008588","GO:0042346"],"synonyms":[{"name":"activation of NIK/NF-kappaB cascade","type":"narrow"},{"name":"activation of non-canonical NF-KB signaling","type":"exact"},{"name":"activation of noncanonical NF-kappaB signaling","type":"exact"},{"name":"activation of noncanonical nuclear factor kappaB (NF-kappaB) pathway","type":"exact"},{"name":"activation of p52-dependent NF-kappaB signaling","type":"narrow"},{"name":"positive regulation of NF-kappaB import into nucleus","type":"narrow"},{"name":"positive regulation of NIK/NF-kappaB cascade","type":"exact"},{"name":"positive regulation of NIK/NF-kappaB signaling","type":"exact"},{"name":"positive regulation of non-canonical NF-KB signaling","type":"exact"},{"name":"positive regulation of noncanonical NF-kappaB signaling","type":"exact"},{"name":"positive regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway","type":"exact"},{"name":"positive regulation of p52-dependent NF-kappaB signaling","type":"narrow"},{"name":"up regulation of NIK/NF-kappaB cascade","type":"exact"},{"name":"up regulation of non-canonical NF-KB signaling","type":"exact"},{"name":"up regulation of noncanonical NF-kappaB signaling","type":"exact"},{"name":"up regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway","type":"exact"},{"name":"up regulation of p52-dependent NF-kappaB signaling","type":"narrow"},{"name":"up-regulation of NIK/NF-kappaB cascade","type":"related"},{"name":"up-regulation of non-canonical NF-KB signaling","type":"exact"},{"name":"up-regulation of noncanonical NF-kappaB signaling","type":"broad"},{"name":"up-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway","type":"exact"},{"name":"up-regulation of p52-dependent NF-kappaB signaling","type":"narrow"},{"name":"upregulation of NIK/NF-kappaB cascade","type":"exact"},{"name":"upregulation of non-canonical NF-KB signaling","type":"exact"},{"name":"upregulation of noncanonical NF-kappaB signaling","type":"broad"},{"name":"upregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway","type":"exact"},{"name":"upregulation of p52-dependent NF-kappaB signaling","type":"narrow"}],"termid":"GO:1901224"}


id: PBO:0039487
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 20 family member A10, pseudogene","termid":"PBO:0039487"}


id: GO:0003137
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.","definition_xrefs":["GOC:mtg_heart"],"gene_count":0,"genotype_count":0,"name":"obsolete Notch signaling pathway involved in heart induction (obsolete GO:0003137)","synonyms":[{"name":"Notch signalling pathway involved in heart induction","type":"exact"}],"termid":"GO:0003137"}


id: GO:0007140
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.","definition_xrefs":["GOC:mah","GOC:dph","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic nuclear division","termid":"GO:0140013"},{"relation_name":"part_of","term_name":"male gamete generation","termid":"GO:0048232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140013"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0140013","GO:0007049"],"is_obsolete":false,"name":"male meiotic nuclear division","synonyms":[{"name":"male meiosis","type":"related"},{"name":"male nuclear division","type":"broad"}],"termid":"GO:0007140"}


id: PBO:0034359
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_syngeny_relationship_with","termid":"PBO:0034359"}


id: GO:0047192
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.","definition_xrefs":["EC:2.3.1.67","MetaCyc:2.3.1.67-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acetyltransferase activity","termid":"GO:0016413"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016746","GO:0003824","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"1-alkylglycerophosphocholine O-acetyltransferase activity","secondary_identifiers":["RHEA:18461"],"synonyms":[{"name":"1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity","type":"related"},{"name":"1-alkyl-2-lysolecithin acetyltransferase activity","type":"related"},{"name":"acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity","type":"related"},{"name":"acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity","type":"related"},{"name":"acetyl-CoA:lyso-PAF acetyltransferase activity","type":"related"},{"name":"acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity","type":"related"},{"name":"blood platelet-activating factor acetyltransferase activity","type":"broad"},{"name":"lyso-GPC:acetyl CoA acetyltransferase activity","type":"broad"},{"name":"lyso-platelet activating factor:acetyl-CoA acetyltransferase activity","type":"broad"},{"name":"lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity","type":"broad"},{"name":"lysopaf:acetyl CoA acetyltransferase activity","type":"broad"},{"name":"platelet-activating factor acylhydrolase activity","type":"broad"},{"name":"platelet-activating factor-synthesizing enzyme activity","type":"broad"}],"termid":"GO:0047192"}


id: PBO:0078049
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 39","termid":"PBO:0078049"}


id: PBO:0074384
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMG6 intronic transcript 1","termid":"PBO:0074384"}


id: PBO:0090812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PI31 proteasome regulator, C-terminal","termid":"PBO:0090812"}


id: PBO:0054044
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1385","termid":"PBO:0054044"}


id: GO:0075222
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sporangium development","termid":"GO:0043582"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sporangium germination","synonyms":[{"name":"direct germination on or near host","type":"narrow"},{"name":"germination of symbiont sporangium on or near host","type":"exact"},{"name":"sporangium germination on or near host","type":"exact"},{"name":"symbiont sporangium germination on or near host","type":"exact"}],"termid":"GO:0075222"}


id: POMBASE_GENE_EX_REL:in_absence_of
data:
  {"annotation_feature_type":"gene","cv_name":"go/extensions/gorel","definition":"a substance is absent","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_absence_of","termid":"POMBASE_GENE_EX_REL:in_absence_of"}


id: PBO:0057498
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 616","termid":"PBO:0057498"}


id: GO:0035581
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.","definition_xrefs":["GOC:signaling","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extracellular negative regulation of signal transduction","termid":"GO:1900116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"sequestering of extracellular ligand from receptor","synonyms":[{"name":"extracellular sequestering of receptor ligand","type":"exact"},{"name":"negative regulation of protein bioavailability","type":"related"}],"termid":"GO:0035581"}


id: PBO:0043434
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cornichon family AMPA receptor auxiliary protein 4","termid":"PBO:0043434"}


id: PBO:0066482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase","termid":"PBO:0066482"}


id: PBO:0050209
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosome binding domain 1 pseudogene 26","termid":"PBO:0050209"}


id: MONDO:0019442
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete congenital toxoplasmosis (obsolete MONDO:0019442)","termid":"MONDO:0019442","xrefs":{"Monarch":{"xref_id":"0019442"}}}


id: PBO:0027198
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-cytoplasmic_microtubule_formation_from_nuclear_microtubules","termid":"PBO:0027198"}


id: GO:0039562
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated suppression of host JAK-STAT cascade","termid":"GO:0039514"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT activity","synonyms":[{"name":"disruption by virus of host JAK-STAT cascade via inhibition of STAT activity","type":"narrow"},{"name":"inhibition by virus of host STAT activity","type":"narrow"},{"name":"suppression by virus of host JAK-STAT cascade via inhibition of STAT activity","type":"exact"},{"name":"suppression by virus of host STAT activity","type":"exact"},{"name":"suppression by virus of host signal transducer and activator of transcription activity","type":"exact"}],"termid":"GO:0039562"}


id: PBO:0031683
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_rate_of_peroxisome_degradation","termid":"PBO:0031683"}


id: MOD:00404
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-methionine residue to homoserine lactone.","definition_xrefs":["Unimod:11#M","OMSSA:57","DeltaMass:90"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cyclized residue","termid":"MOD:00601"},{"relation_name":"is_a","term_name":"modified L-methionine residue","termid":"MOD:00913"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homoserine lactone","synonyms":[{"name":"Homoserine lactone","type":"related"},{"name":"Met->Hsl","type":"related"},{"name":"ctermpephselactm","type":"exact"}],"termid":"MOD:00404"}


id: PBO:0003347
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TENA/THI domain","termid":"PBO:0003347"}


id: MONDO:0800178
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Progressive, bilateral, and irreversible sensorineural hearing loss as a frequently encountered side effect of platinum-based chemotherapy such as cisplatin and carboplatin.","definition_xrefs":["PMID:32429551"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensorineural hearing loss disorder","termid":"MONDO:0020678"},{"relation_name":"is_a","term_name":"poisoning","termid":"MONDO:0029000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"platinum-induced ototoxicity","synonyms":[{"name":"deafness, platinum-induced","type":"exact"},{"name":"platinum-related ototoxicity","type":"exact"}],"termid":"MONDO:0800178","xrefs":{"Monarch":{"xref_id":"0800178"}}}


id: GO:0032761
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lymphotoxin A production","termid":"GO:0032681"},{"relation_name":"is_a","term_name":"positive regulation of protein metabolic process","termid":"GO:0051247"},{"relation_name":"is_a","term_name":"positive regulation of tumor necrosis factor superfamily cytokine production","termid":"GO:1903557"},{"relation_name":"positively_regulates","term_name":"lymphotoxin A production","termid":"GO:0032641"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of lymphotoxin A production","secondary_identifiers":["GO:0043017"],"synonyms":[{"name":"activation of lymphotoxin A production","type":"narrow"},{"name":"positive regulation of LTA production","type":"exact"},{"name":"positive regulation of TNF-beta production","type":"exact"},{"name":"positive regulation of lymphotoxin A biosynthetic process","type":"narrow"},{"name":"positive regulation of lymphotoxin-alpha production","type":"exact"},{"name":"positive regulation of tumor necrosis factor-beta production","type":"exact"},{"name":"stimulation of lymphotoxin A production","type":"narrow"},{"name":"up regulation of lymphotoxin A production","type":"exact"},{"name":"up-regulation of lymphotoxin A production","type":"exact"},{"name":"upregulation of lymphotoxin A production","type":"exact"}],"termid":"GO:0032761"}


id: PR:Q9USY2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A squamous cell carcinoma antigen recognized by T-cells 3 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04004","PANTHER:PTHR23269:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized RNA-binding protein C1861.04c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1861.04c","secondary_identifiers":["UniProtKB:Q9USY2"],"synonyms":[{"name":"Spom972h-SART3","type":"exact"}],"termid":"PR:Q9USY2"}


id: PBO:0091057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit L54","termid":"PBO:0091057"}


id: MOD:00287
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-proline residue to a (2S,3R,4S)-3,4-dihydroxyproline.","definition_xrefs":["DeltaMass:0","Unimod:425#P","RESID:AA0282","PubMed:12686488","ChEBI:141803"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dihydroxylated proline","termid":"MOD:00866"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"(2S,3R,4S)-3,4-dihydroxyproline","synonyms":[{"name":"(2S,3R,4S)-3,4-dihydroxyproline","type":"exact"},{"name":"(2S,3R,4S)-3,4-dihydroxypyrrolidine-2-carboxylic acid","type":"exact"},{"name":"2,3-trans-3,4-cis-3,4-dihydroxy-L-proline","type":"exact"},{"name":"2-alpha-3-beta-4-beta-3,4-dihydroxyproline","type":"exact"},{"name":"3,4-Dihydroxylation (of Proline)","type":"exact"},{"name":"3,4-dihydroxylated L-proline","type":"exact"},{"name":"34Hy2Pro","type":"exact"},{"name":"Dioxidation","type":"related"},{"name":"MOD_RES (3R,4S)-3,4-dihydroxyproline","type":"exact"},{"name":"dihydroxy","type":"related"},{"name":"trans-2,3-cis-3,4-dihydroxy-L-proline","type":"exact"}],"termid":"MOD:00287"}


id: PBO:0072369
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S26 pseudogene 55","termid":"PBO:0072369"}


id: MONDO:0014780
data:
  {"annotated_genes":["SJAG_06383"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84996],"is_not":false,"summary":null,"term":"MONDO:0014780"}]},"cv_name":"mondo","definition":"Any hyperphosphatasia-intellectual disability syndrome in which the cause of the disease is a mutation in the PIGY gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hyperphosphatasia-intellectual disability syndrome","termid":"MONDO:0016596"}],"gene_count":1,"genes_by_uniquename":{"SJAG_06383":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0024322"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0024322","MONDO:0005066"],"is_obsolete":false,"name":"hyperphosphatasia with intellectual disability syndrome 6","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4225201","GARD:18354","OMIM:616809","MEDGEN:906509","DOID:0070437"],"synonyms":[{"name":"HPMRS6","type":"exact"},{"name":"PIGY hyperphosphatasia-intellectual disability syndrome","type":"exact"},{"name":"glycosylphosphatidylinositol biosynthesis defect 12","type":"related"},{"name":"hyperphosphatasia with intellectual disability syndrome 6","type":"exact"},{"name":"hyperphosphatasia with intellectual disability syndrome 6; HPMRS6","type":"exact"},{"name":"hyperphosphatasia with intellectual disability syndrome type 6","type":"exact"},{"name":"hyperphosphatasia with mental retardation syndrome 6","type":"exact"},{"name":"hyperphosphatasia with mental retardation syndrome type 6","type":"exact"},{"name":"hyperphosphatasia-intellectual disability syndrome caused by mutation in PIGY","type":"exact"}],"termid":"MONDO:0014780","terms_by_termid":{"MONDO:0014780":null},"xrefs":{"Monarch":{"xref_id":"0014780"}}}


id: GO:0071808
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).","definition_xrefs":["GOC:mah","GOC:sl","PMID:20108326"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"axoneme","termid":"GO:0005930"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"satellite fibril","termid":"GO:0071808"}


id: PBO:0074258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier organic anion transporter family member 3A1","termid":"PBO:0074258"}


id: SO:1001249
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A CDS that is supported by domain similarity.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"supported_by_domain_match","termid":"SO:0000908"},{"relation_name":"is_a","term_name":"CDS_supported_by_sequence_similarity_data","termid":"SO:1001251"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDS_supported_by_domain_match_data","synonyms":[{"name":"CDS supported by domain match data","type":"exact"}],"termid":"SO:1001249"}


id: PBO:0041301
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C2CD4D and THEM5 antisense RNA 1","termid":"PBO:0041301"}


id: PBO:0113813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome large subunit export factor, Alb1 family, Ecm1","termid":"PBO:0113813"}


id: PBO:0041967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 9B","termid":"PBO:0041967"}


id: MONDO:0700059
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Actinobacillus infectious disease that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial infectious disease, non-human animal","termid":"MONDO:0700050"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Actinobacillus infectious disease, non-human animal","termid":"MONDO:0700059","xrefs":{"Monarch":{"xref_id":"0700059"}}}


id: GO:0048677
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Long distance growth of a single axon process involved in regeneration of the neuron.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"axon extension","termid":"GO:0048675"},{"relation_name":"is_a","term_name":"sprouting of injured axon","termid":"GO:0048682"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"axon extension involved in regeneration","termid":"GO:0048677"}


id: PBO:0029032
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K9_acetylation_at_telomere","termid":"PBO:0029032"}


id: GO:0061067
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.","definition_xrefs":["GOC:kmv","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of nematode larval development","termid":"GO:0061064"},{"relation_name":"is_a","term_name":"regulation of dauer larval development","termid":"GO:0061065"},{"relation_name":"negatively_regulates","term_name":"dauer larval development","termid":"GO:0040024"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of dauer larval development","termid":"GO:0061067"}


id: PBO:0079507
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thioredoxin pseudogene 5","termid":"PBO:0079507"}


id: GO:1902620
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding.","definition_xrefs":["GOC:TermGenie","PMID:22939623","GO_REF:0000059","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of microtubule minus-end binding","termid":"GO:1902619"},{"relation_name":"is_a","term_name":"positive regulation of microtubule binding","termid":"GO:1904528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of microtubule minus-end binding","synonyms":[{"name":"activation of microtubule minus-end binding","type":"narrow"},{"name":"up regulation of microtubule minus-end binding","type":"exact"},{"name":"up-regulation of microtubule minus-end binding","type":"exact"},{"name":"upregulation of microtubule minus-end binding","type":"exact"}],"termid":"GO:1902620"}


id: MONDO:0023558
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"muscle tissue disorder","termid":"MONDO:0003939"},{"relation_name":"is_a","term_name":"congenital hypothyroidism","termid":"MONDO:0018612"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kocher-debre-Semelaigne syndrome","secondary_identifiers":["MESH:C537211","icd11.foundation:109007822"],"synonyms":[{"name":"Kocher debre Semelaigne disease","type":"related"},{"name":"association of muscular pseudohypertrophy and hypothyroidism in children","type":"related"}],"termid":"MONDO:0023558","xrefs":{"Monarch":{"xref_id":"0023558"}}}


id: MONDO:0009419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Woodhouse-Sakati syndrome is a multisystemic disorder characterized by hypogonadism, alopecia, diabetes mellitus, intellectual deficit and extrapyramidal signs with choreoathetoid movements and dystonia.","definition_xrefs":["Orphanet:3464"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"excluded_subClassOf","term_name":"diabetes mellitus","termid":"MONDO:0005015"},{"relation_name":"is_a","term_name":"congenital hypogonadotropic hypogonadism","termid":"MONDO:0015770"},{"relation_name":"is_a","term_name":"neurodegeneration with brain iron accumulation","termid":"MONDO:0018307"},{"relation_name":"is_a","term_name":"inherited dystonia","termid":"MONDO:0044807"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0003441","MONDO:0002039","MONDO:0005559"],"is_obsolete":false,"name":"Woodhouse-Sakati syndrome","secondary_identifiers":["MESH:C536742","OMIM:241080","GARD:5592","SCTID:237616002","icd11.foundation:1893572805","DOID:0112264","ICD9:759.89","MEDGEN:83337","UMLS:C0342286"],"synonyms":[{"name":"Woodhouse-Sakati syndrome","type":"exact"},{"name":"diabetes-hypogonadism-deafness-intellectual disability syndrome","type":"exact"},{"name":"extrapyramidal disorder, progressive, with primary hypogonadism, intellectual disability, and alopecia","type":"related"},{"name":"extrapyramidal disorder, progressive, with primary hypogonadism, mental retardation, and alopecia","type":"related"},{"name":"hypogonadism, alopecia, diabetes mellitus, intellectual disability, deafness, and extrapyramidal syndrome","type":"related"},{"name":"hypogonadism, alopecia, diabetes mellitus, mental retardation, deafness, and extrapyramidal syndrome","type":"related"},{"name":"hypogonadism, diabetes mellitus, alopecia, intellectual disability, and electrocardiographic abnormalities","type":"related"},{"name":"hypogonadism, diabetes mellitus, alopecia, mental retardation, and electrocardiographic abnormalities","type":"related"},{"name":"woodhouse Sakati syndrome","type":"related"},{"name":"woodhouse-Sakati syndrome","type":"exact"}],"termid":"MONDO:0009419","xrefs":{"Monarch":{"xref_id":"0009419"}}}


id: MONDO:0030376
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Martsolf syndrome","termid":"MONDO:0023910"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"Martsolf syndrome 2","secondary_identifiers":["UMLS:C5543626","MEDGEN:1779703","OMIM:619420"],"synonyms":[{"name":"MARTS2","type":"exact"}],"termid":"MONDO:0030376","xrefs":{"Monarch":{"xref_id":"0030376"}}}


id: PBO:0036113
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_protein_glycosylation_during_vegetative_growth","termid":"PBO:0036113"}


id: PBO:0060705
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit A5 pseudogene 2","termid":"PBO:0060705"}


id: GO:0021705
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.","definition_xrefs":["GOC:cls","GOC:dgh","GOC:dph","GOC:jid","ISBN:0838580343","GO_REF:0000021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"pons formation","termid":"GO:0021584"},{"relation_name":"part_of","term_name":"locus ceruleus morphogenesis","termid":"GO:0021704"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"locus ceruleus formation","termid":"GO:0021705"}


id: GO:1902112
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.","definition_xrefs":["GOC:TermGenie","PMID:12100563"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"},{"relation_name":"is_a","term_name":"response to diethyl maleate","termid":"GO:1902111"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to diethyl maleate","termid":"GO:1902112"}


id: FYPO:0002788
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are smaller than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vacuolar morphology during vegetative growth","termid":"FYPO:0000368"},{"relation_name":"is_a","term_name":"small vacuoles","termid":"FYPO:0002787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"small vacuoles during vegetative growth","synonyms":[{"name":"decreased vacuole size during vegetative growth","type":"exact"},{"name":"reduced vacuole size during vegetative growth","type":"exact"},{"name":"small vacuoles during mitotic cell cycle","type":"related"}],"termid":"FYPO:0002788"}


id: GO:0044472
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism.","definition_xrefs":["PMID:20920515","GOC:jl","GOC:fj"],"direct_ancestors":[{"relation_name":"is_a","term_name":"envenomation resulting in modulation of ion channel activity in another organism","termid":"GO:0044560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"envenomation resulting in modulation of calcium channel activity in another organism","synonyms":[{"name":"envenomation resulting in modulation of calcium channel activity in other organism","type":"exact"}],"termid":"GO:0044472"}


id: MONDO:0013268
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Frontonasal dysplasia with alopecia and genital anomaly is a new phenotype of frontonasal dysplasia associated with total alopecia and hypogonadism.","definition_xrefs":["Orphanet:228390"],"direct_ancestors":[{"relation_name":"is_a","term_name":"integumentary system disorder","termid":"MONDO:0002051"},{"relation_name":"is_a","term_name":"frontonasal dysplasia","termid":"MONDO:0016643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"frontonasal dysplasia with alopecia and genital anomaly","secondary_identifiers":["SCTID:725029001","UMLS:C3150703","GARD:12641","MEDGEN:462053","DOID:0081046","OMIM:613451"],"synonyms":[{"name":"ALX4-related FNDAG","type":"exact"},{"name":"FND2","type":"related"},{"name":"craniofrontonasal dysplasia with alopecia and hypogonadism","type":"exact"},{"name":"frontonasal dysplasia 2","type":"related"},{"name":"frontonasal dysplasia type 2","type":"exact"},{"name":"frontonasal dysplasia with alopecia and genital abnomality","type":"exact"}],"termid":"MONDO:0013268","xrefs":{"Monarch":{"xref_id":"0013268"}}}


id: PBO:0036356
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCR4-Not complex NOT box subunit Not3/5","termid":"PBO:0036356"}


id: GO:0102955
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = menaquinol-7 + S-adenosyl-L-homocysteine + H+.","definition_xrefs":["GOC:pz","PMID:1444716","PMID:9045837"],"gene_count":0,"genotype_count":0,"name":"obsolete S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity (obsolete GO:0102955)","termid":"GO:0102955"}


id: MONDO:0012318
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukemia, chronic lymphocytic, susceptibility to, 1","secondary_identifiers":["MEDGEN:351271","OMIM:609630","UMLS:C1864995"],"synonyms":[{"name":"Clls1","type":"related"},{"name":"leukemia, chronic lymphocytic, susceptibility to, 1","type":"exact"},{"name":"leukemia, chronic lymphocytic, susceptibility to, type 1","type":"exact"}],"termid":"MONDO:0012318","xrefs":{"Monarch":{"xref_id":"0012318"}}}


id: GO:0044835
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria.","definition_xrefs":["GOC:mengo_curators","PMID:22128188"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrogen biosynthetic process","termid":"GO:1902422"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hydrogen generation via nitrogenase","termid":"GO:0044835"}


id: GO:1903683
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.","definition_xrefs":["GO_REF:0000058","GOC:als","GOC:TermGenie","PMID:18394891"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell-cell adhesion","termid":"GO:0022409"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"is_a","term_name":"regulation of epithelial cell-cell adhesion involved in epithelium migration","termid":"GO:1903681"},{"relation_name":"positively_regulates","term_name":"epithelial cell-cell adhesion involved in epithelium migration","termid":"GO:0090137"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"positive regulation of epithelial cell-cell adhesion involved in epithelium migration","synonyms":[{"name":"activation of epithelial cell-cell adhesion involved in epithelium migration","type":"narrow"},{"name":"up regulation of epithelial cell-cell adhesion involved in epithelium migration","type":"exact"},{"name":"up-regulation of epithelial cell-cell adhesion involved in epithelium migration","type":"exact"},{"name":"upregulation of epithelial cell-cell adhesion involved in epithelium migration","type":"exact"}],"termid":"GO:1903683"}


id: GO:0150147
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The disaggregation of a cell-cell junction into its constituent components.","definition_xrefs":["GOC:aruk","PMID:25490267"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell junction organization","termid":"GO:0045216"},{"relation_name":"is_a","term_name":"cell junction disassembly","termid":"GO:0150146"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell-cell junction disassembly","termid":"GO:0150147"}


id: FYPO:0004825
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly lower than the range in wild type cells, but remains at the same level over successive generations.","definition_xrefs":["PomBase:mah","PMID:25417108"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased rDNA copy number during vegetative growth","termid":"FYPO:0006494"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"stably decreased rDNA copy number during vegetative growth","synonyms":[{"name":"stable shortened rDNA during vegetative growth","type":"related"},{"name":"stably decreased rDNA copy number during mitotic cell cycle","type":"related"},{"name":"stably decreased ribosomal DNA copy number during vegetative growth","type":"exact"}],"termid":"FYPO:0004825"}


id: GO:0031047
data:
  {"annotated_genes":["SJAG_00058","SJAG_02119","SJAG_04407","SJAG_03356","SJAG_04030","SJAG_03689","SJAG_01579","SJAG_04369","SJAG_03680","SJAG_04061","SJAG_02594","SJAG_02908","SJAG_03193","SJAG_01176","SJAG_01836","SJAG_01008","SJAG_02725","SJAG_03042","SJAG_03664","SJAG_04141","SJAG_04768","SJAG_01331","SJAG_00087","SJAG_01867","SJAG_04253","SJAG_03916","SJAG_02622","SJAG_03745","SJAG_02817","SJAG_03883","SJAG_00756","SJAG_04942","SJAG_00414","SJAG_02621","SJAG_01601","SJAG_02409","SJAG_03635","SJAG_04574","SJAG_00701","SJAG_01540"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[86712,88995,91454,105708,111000,114792,117244],"is_not":false,"summary":null,"term":"GO:0031047"},{"annotations":[98754,109627,115116,117214,98316],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033562"},{"annotations":[107643],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0060906"},{"annotations":[106938,117105,117217,87586],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1990431"},{"annotations":[116882],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0010964"},{"annotations":[92026,117243,91065],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0043628"},{"annotations":[98756,108269,103269,106512,117106,106939,112192,113703,117218,112801,111001],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031048"},{"annotations":[117220,106940],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1990432"},{"annotations":[108270,98759],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030422"},{"annotations":[105470],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902795"},{"annotations":[113123],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0141194"},{"annotations":[87989,111348,113438,117107,90478,94533,95927,112803,88044,98327,93292,109632,105709,109797,110353,113704,115121,114557,116827,98760,117940,117221],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140727"}]},"cv_name":"biological_process","definition":"A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.","definition_xrefs":["PMID:15020054"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of gene expression","termid":"GO:0010629"}],"gene_count":40,"genes_by_uniquename":{"SJAG_00058":null,"SJAG_00087":null,"SJAG_00414":null,"SJAG_00701":null,"SJAG_00756":null,"SJAG_01008":null,"SJAG_01176":null,"SJAG_01331":null,"SJAG_01540":null,"SJAG_01579":null,"SJAG_01601":null,"SJAG_01836":null,"SJAG_01867":null,"SJAG_02119":null,"SJAG_02409":null,"SJAG_02594":null,"SJAG_02621":null,"SJAG_02622":null,"SJAG_02725":null,"SJAG_02817":null,"SJAG_02908":null,"SJAG_03042":null,"SJAG_03193":null,"SJAG_03356":null,"SJAG_03635":null,"SJAG_03664":null,"SJAG_03680":null,"SJAG_03689":null,"SJAG_03745":null,"SJAG_03883":null,"SJAG_03916":null,"SJAG_04030":null,"SJAG_04061":null,"SJAG_04141":null,"SJAG_04253":null,"SJAG_04369":null,"SJAG_04407":null,"SJAG_04574":null,"SJAG_04768":null,"SJAG_04942":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulatory ncRNA-mediated gene silencing","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"RNA-dependent gene silencing","type":"exact"},{"name":"RNA-mediated gene silencing","type":"related"},{"name":"gene silencing by RNA","type":"related"}],"termid":"GO:0031047","terms_by_termid":{"GO:0010964":null,"GO:0030422":null,"GO:0031047":null,"GO:0031048":null,"GO:0033562":null,"GO:0043628":null,"GO:0060906":null,"GO:0140727":null,"GO:0141194":null,"GO:1902795":null,"GO:1990431":null,"GO:1990432":null}}


id: GO:0033899
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.","definition_xrefs":["EC:4.6.1.20"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA endonuclease activity, producing 3'-phosphomonoesters","termid":"GO:0016892"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0003824","GO:0140098","GO:0003674","GO:0016787","GO:0016788"],"is_obsolete":false,"name":"ribonuclease U2 activity","secondary_identifiers":["MetaCyc:RXN-19928"],"synonyms":[{"name":"RNase U2 activity","type":"related"},{"name":"pleospora RNase activity","type":"exact"},{"name":"purine specific endoribonuclease activity","type":"exact"},{"name":"purine-specific RNase activity","type":"exact"},{"name":"purine-specific ribonuclease activity","type":"exact"},{"name":"ribonuclease (purine) activity","type":"exact"},{"name":"trichoderma koningi RNase III activity","type":"exact"}],"termid":"GO:0033899"}


id: PBO:0013444
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMARCAD1 family ATP-dependent DNA helicase Fft3","termid":"PBO:0013444"}


id: PATO:0000539
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000539 drought sensitivity value (obsolete PATO:0000539)","termid":"PATO:0000539"}


id: PBO:0114433
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PIEZO1 antisense RNA 1","termid":"PBO:0114433"}


id: PBO:0055610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3049","termid":"PBO:0055610"}


id: PBO:0031148
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_beta-glucan_level","termid":"PBO:0031148"}


id: PBO:0038787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosine deaminase","termid":"PBO:0038787"}


id: PBO:0044032
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CSPG4 pseudogene 1 Y-linked","termid":"PBO:0044032"}


id: PBO:0028109
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_bis(5'-adenosyl)-hexaphosphatase_activity","termid":"PBO:0028109"}


id: PBO:0068093
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 400","termid":"PBO:0068093"}


id: PBO:0064999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PR/SET domain 6","termid":"PBO:0064999"}


id: PBO:0062238
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily BB member 1 pseudogene","termid":"PBO:0062238"}


id: PBO:0000395
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.1.7","termid":"PBO:0000395"}


id: PBO:0070303
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY1 pseudogene 9","termid":"PBO:0070303"}


id: MONDO:0000654
data:
  {"annotated_genes":["SJAG_02855","SJAG_00031"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84558],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010621"},{"annotations":[85911],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007908"}]},"cv_name":"mondo","definition":"A non-metastasizing neoplasm that arises from the connective and soft tissue. Representative examples include lipoma, leiomyoma, fibroma, and osteoma.","definition_xrefs":["NCIT:C53684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system benign neoplasm","termid":"MONDO:0000636"},{"relation_name":"is_a","term_name":"connective tissue disorder","termid":"MONDO:0003900"},{"relation_name":"is_a","term_name":"connective and soft tissue neoplasm","termid":"MONDO:0044334"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00031":null,"SJAG_02855":null},"genotype_count":0,"is_obsolete":false,"name":"benign connective and soft tissue neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C3377","MEDGEN:83866","SCTID:387837005","DOID:0060123","UMLS:C0347481"],"synonyms":[{"name":"benign connective and soft tissue neoplasm","type":"exact"},{"name":"benign connective and soft tissue tumor","type":"exact"},{"name":"benign connective and soft tissue tumour","type":"exact"},{"name":"benign mesenchymal cell neoplasm","type":"exact"},{"name":"benign neoplasm of the soft tissue and bone","type":"exact"},{"name":"benign tumor of the soft tissue and bone","type":"exact"},{"name":"benign tumour of the soft tissue and bone","type":"exact"},{"name":"connective and soft tissue neoplasm, benign","type":"exact"},{"name":"connective tissue benign neoplasm","type":"exact"},{"name":"neoplasm of soft tissue","type":"related"},{"name":"neoplasm of soft tissues","type":"related"},{"name":"soft tissue benign neoplasm","type":"related"},{"name":"tumor of the soft tissue","type":"related"},{"name":"tumour of the soft tissue","type":"related"}],"termid":"MONDO:0000654","terms_by_termid":{"MONDO:0007908":null,"MONDO:0010621":null},"xrefs":{"Monarch":{"xref_id":"0000654"}}}


id: PBO:0075345
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SOS Ras/Rac guanine nucleotide exchange factor 1","termid":"PBO:0075345"}


id: GO:0035381
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ligand-gated channel activity","termid":"GO:0022834"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"ATP-gated ion channel activity","termid":"GO:0035381"}


id: PBO:0003118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin family protein (predicted)","termid":"PBO:0003118"}


id: PBO:0072262
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPS21 divergent transcript","termid":"PBO:0072262"}


id: PBO:0051262
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable (III)-67-4 (pseudogene)","termid":"PBO:0051262"}


id: PBO:0082627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly of large protein complexes such as box C/D snoRNPs and RNA polymerase II; contains a single TPR domain with at least two TPR motifs; plays a role in determining prion variants","termid":"PBO:0082627"}


id: GO:0047200
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = L-2-acetamido-6-oxopimelate + CoA.","definition_xrefs":["RHEA:13085","EC:2.3.1.89"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acetyltransferase activity","termid":"GO:0008080"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016746","GO:0016740","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"tetrahydrodipicolinate N-acetyltransferase activity","secondary_identifiers":["MetaCyc:2.3.1.89-RXN","KEGG_REACTION:R04364"],"synonyms":[{"name":"acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity","type":"related"},{"name":"acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity","type":"related"},{"name":"acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity","type":"related"},{"name":"tetrahydrodipicolinate acetylase activity","type":"related"},{"name":"tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity","type":"related"}],"termid":"GO:0047200"}


id: PBO:0074791
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 11B","termid":"PBO:0074791"}


id: GO:0045065
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"T cell differentiation","termid":"GO:0030217"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cytotoxic T cell differentiation","synonyms":[{"name":"cytotoxic T cell development","type":"related"},{"name":"cytotoxic T lymphocyte selection","type":"exact"},{"name":"cytotoxic T-cell selection","type":"exact"},{"name":"cytotoxic T-lymphocyte selection","type":"exact"}],"termid":"GO:0045065"}


id: PBO:0077474
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 196","termid":"PBO:0077474"}


id: GO:0070249
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.","definition_xrefs":["GOC:mtg_apoptosis","ISBN:0781765196","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of lymphocyte apoptotic process","termid":"GO:0070230"},{"relation_name":"is_a","term_name":"regulation of natural killer cell apoptotic process","termid":"GO:0070247"},{"relation_name":"positively_regulates","term_name":"natural killer cell apoptotic process","termid":"GO:0070246"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of natural killer cell apoptotic process","synonyms":[{"name":"activation of natural killer cell apoptosis","type":"narrow"},{"name":"positive regulation of NK cell apoptosis","type":"exact"},{"name":"positive regulation of natural killer cell apoptosis","type":"narrow"},{"name":"stimulation of natural killer cell apoptosis","type":"narrow"},{"name":"up regulation of natural killer cell apoptosis","type":"exact"},{"name":"up-regulation of natural killer cell apoptosis","type":"exact"},{"name":"upregulation of natural killer cell apoptosis","type":"exact"}],"termid":"GO:0070249"}


id: PBO:0076986
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THAP domain containing 4","termid":"PBO:0076986"}


id: PBO:0025441
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G6PD deficiency","termid":"PBO:0025441"}


id: PBO:0058818
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 7975","termid":"PBO:0058818"}


id: MONDO:0005653
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete asbestosis (obsolete MONDO:0005653)","termid":"MONDO:0005653","xrefs":{"Monarch":{"xref_id":"0005653"}}}


id: PBO:0048059
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ferritin heavy chain 1 pseudogene 8","termid":"PBO:0048059"}


id: GO:1900065
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of ethanol catabolic process.","definition_xrefs":["GOC:TermGenie","PMID:10608811","PMID:7760841"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of alcohol catabolic process","termid":"GO:1900419"},{"relation_name":"regulates","term_name":"ethanol catabolic process","termid":"GO:0006068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"regulation of ethanol catabolic process","synonyms":[{"name":"regulation of ethanol breakdown","type":"exact"},{"name":"regulation of ethanol catabolism","type":"exact"},{"name":"regulation of ethanol degradation","type":"exact"}],"termid":"GO:1900065"}


id: PBO:0077978
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ala (anticodon TGC) 1-1","termid":"PBO:0077978"}


id: PBO:0064949
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRAME nuclear receptor transcriptional regulator","termid":"PBO:0064949"}


id: GO:0006647
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylethanolamine biosynthetic process","termid":"GO:0006646"},{"relation_name":"is_a","term_name":"phosphatidyl-N-monomethylethanolamine metabolic process","termid":"GO:0046468"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"phosphatidyl-N-monomethylethanolamine biosynthetic process","synonyms":[{"name":"PMME biosynthesis","type":"exact"},{"name":"PMME biosynthetic process","type":"exact"},{"name":"phosphatidyl-N-monomethylethanolamine anabolism","type":"exact"},{"name":"phosphatidyl-N-monomethylethanolamine biosynthesis","type":"exact"},{"name":"phosphatidyl-N-monomethylethanolamine formation","type":"exact"},{"name":"phosphatidyl-N-monomethylethanolamine synthesis","type":"exact"}],"termid":"GO:0006647"}


id: PBO:0058061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4281","termid":"PBO:0058061"}


id: PBO:0031598
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_cell_cycle_arrest_in_mitotic_metaphase","termid":"PBO:0031598"}


id: GO:0140712
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of a Frizzled Nuclear Import pathway.","definition_xrefs":["PMID:22579286","PMID:22510459"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of Frizzled Nuclear Import pathway","termid":"GO:0140710"},{"relation_name":"is_a","term_name":"negative regulation of non-canonical Wnt signaling pathway","termid":"GO:2000051"},{"relation_name":"negatively_regulates","term_name":"Frizzled Nuclear Import pathway","termid":"GO:0140709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of Frizzled Nuclear Import pathway","synonyms":[{"name":"negative regulation of FNI","type":"broad"},{"name":"negative regulation of Frizzled Nuclear Import Wnt Pathway","type":"exact"}],"termid":"GO:0140712"}


id: MONDO:0014652
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any exudative vitreoretinopathy in which the cause of the disease is a mutation in the ZNF408 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"exudative vitreoretinopathy","termid":"MONDO:0019516"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005559"],"is_obsolete":false,"name":"exudative vitreoretinopathy 6","secondary_identifiers":["OMIM:616468","UMLS:C4225316","DOID:0111410","MEDGEN:902559","GARD:16118"],"synonyms":[{"name":"EVR6","type":"related"},{"name":"ZNF408 exudative vitreoretinopathy","type":"exact"},{"name":"exudative vitreoretinopathy 6","type":"exact"},{"name":"exudative vitreoretinopathy caused by mutation in ZNF408","type":"exact"},{"name":"exudative vitreoretinopathy type 6","type":"exact"}],"termid":"MONDO:0014652","xrefs":{"Monarch":{"xref_id":"0014652"}}}


id: GO:0032687
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.","definition_xrefs":["PMID:15546383","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of type I interferon production","termid":"GO:0032480"},{"relation_name":"is_a","term_name":"regulation of interferon-alpha production","termid":"GO:0032647"},{"relation_name":"negatively_regulates","term_name":"interferon-alpha production","termid":"GO:0032607"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of interferon-alpha production","secondary_identifiers":["GO:0045355","GO:1902740"],"synonyms":[{"name":"down regulation of interferon-alpha production","type":"exact"},{"name":"down-regulation of interferon-alpha production","type":"exact"},{"name":"downregulation of interferon-alpha production","type":"exact"},{"name":"inhibition of interferon-alpha production","type":"narrow"},{"name":"negative regulation of interferon-alpha biosynthetic process","type":"narrow"},{"name":"negative regulation of interferon-alpha secretion","type":"narrow"}],"termid":"GO:0032687"}


id: PBO:0084506
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis","termid":"PBO:0084506"}


id: GO:0009124
data:
  {"annotated_genes":["SJAG_01070","SJAG_04123","SJAG_04845","SJAG_03811","SJAG_04970","SJAG_01859","SJAG_06634","SJAG_03164","SJAG_01081","SJAG_04354","SJAG_00444","SJAG_00533","SJAG_00044","SJAG_02364","SJAG_03355","SJAG_03771","SJAG_01814","SJAG_04681","SJAG_04627","SJAG_01298","SJAG_03708","SJAG_04487","SJAG_04709","SJAG_03140","SJAG_00964","SJAG_04713","SJAG_02850","SJAG_00694","SJAG_01661","SJAG_04882","SJAG_04634","SJAG_00197"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88089,102597],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044208"},{"annotations":[98765,102598,113639,96998,116484,109507,118104,109396],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006189"},{"annotations":[92613,97696,111054,115852,88659],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044205"},{"annotations":[115973,92733],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044209"},{"annotations":[67423],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009224"},{"annotations":[107531,88584],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006231"},{"annotations":[107532,98185],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006226"},{"annotations":[114863],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009398"},{"annotations":[100378,107423,59180],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006177"},{"annotations":[92949],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032263"},{"annotations":[118105],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006188"},{"annotations":[92951,100998],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032264"},{"annotations":[114092,96906,109074],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009156"},{"annotations":[92169,87662,91169,114048,86680],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044206"},{"annotations":[92953],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032265"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside monophosphate metabolic process","termid":"GO:0009123"},{"relation_name":"is_a","term_name":"nucleoside phosphate biosynthetic process","termid":"GO:1901293"}],"gene_count":32,"genes_by_uniquename":{"SJAG_00044":null,"SJAG_00197":null,"SJAG_00444":null,"SJAG_00533":null,"SJAG_00694":null,"SJAG_00964":null,"SJAG_01070":null,"SJAG_01081":null,"SJAG_01298":null,"SJAG_01661":null,"SJAG_01814":null,"SJAG_01859":null,"SJAG_02364":null,"SJAG_02850":null,"SJAG_03140":null,"SJAG_03164":null,"SJAG_03355":null,"SJAG_03708":null,"SJAG_03771":null,"SJAG_03811":null,"SJAG_04123":null,"SJAG_04354":null,"SJAG_04487":null,"SJAG_04627":null,"SJAG_04634":null,"SJAG_04681":null,"SJAG_04709":null,"SJAG_04713":null,"SJAG_04845":null,"SJAG_04882":null,"SJAG_04970":null,"SJAG_06634":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0055086","GO:0008150"],"is_obsolete":false,"name":"nucleoside monophosphate biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"nucleoside monophosphate anabolism","type":"exact"},{"name":"nucleoside monophosphate biosynthesis","type":"exact"},{"name":"nucleoside monophosphate formation","type":"exact"},{"name":"nucleoside monophosphate synthesis","type":"exact"}],"termid":"GO:0009124","terms_by_termid":{"GO:0006177":null,"GO:0006188":null,"GO:0006189":null,"GO:0006226":null,"GO:0006231":null,"GO:0009156":null,"GO:0009224":null,"GO:0009398":null,"GO:0032263":null,"GO:0032264":null,"GO:0032265":null,"GO:0044205":null,"GO:0044206":null,"GO:0044208":null,"GO:0044209":null}}


id: MONDO:0008879
data:
  {"annotated_genes":["SJAG_02024"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84801],"is_not":false,"summary":null,"term":"MONDO:0008879"}]},"cv_name":"mondo","definition":"Bowen-Conradi syndrome (BCS) is a lethal autosomal recessive ribosomal biogenesis disorder characterized by severe prenatal and postnatal growth retardation, microcephaly, a distinctive facial appearance, extreme psychomotor delay, hip and knee contractures and rockerbottom feet.","definition_xrefs":["Orphanet:1270"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02024":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Bowen-Conradi syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:C537081","GARD:5950","NORD:869","ICD9:759.89","OMIM:211180","MEDGEN:349160","icd11.foundation:1713786719","SCTID:711153001","UMLS:C1859405","DOID:0050684"],"synonyms":[{"name":"BWCNS","type":"exact"},{"name":"Bowen Hutterite Syndrome","type":"exact"},{"name":"Bowen Hutterite syndrome","type":"exact"},{"name":"Bowen Hutterite syndrome (formerly)","type":"exact"},{"name":"Bowen Hutterite syndrome, formerly","type":"exact"},{"name":"Bowen syndrome, Hutterite type","type":"exact"},{"name":"Bowen-Conradi Hutterite syndrome","type":"exact"},{"name":"Bowen-Conradi syndrome","type":"exact"}],"termid":"MONDO:0008879","terms_by_termid":{"MONDO:0008879":null},"xrefs":{"Monarch":{"xref_id":"0008879"}}}


id: GO:1900674
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of olefin.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrocarbon biosynthetic process","termid":"GO:0120251"},{"relation_name":"is_a","term_name":"olefinic compound biosynthetic process","termid":"GO:0120255"},{"relation_name":"is_a","term_name":"olefin metabolic process","termid":"GO:1900673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"olefin biosynthetic process","synonyms":[{"name":"olefin anabolism","type":"exact"},{"name":"olefin biosynthesis","type":"exact"},{"name":"olefin formation","type":"exact"},{"name":"olefin synthesis","type":"exact"}],"termid":"GO:1900674"}


id: PBO:0051821
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interferon regulatory factor 1","termid":"PBO:0051821"}


id: PBO:0038480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP binding cassette subfamily B member 5","termid":"PBO:0038480"}


id: GO:0004702
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.","definition_xrefs":["GOC:bf","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity (obsolete GO:0004702)","synonyms":[{"name":"receptor signaling protein serine/threonine kinase activity","type":"exact"},{"name":"receptor signalling protein serine/threonine kinase activity","type":"exact"}],"termid":"GO:0004702"}


id: PBO:0059180
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MRE11 homolog, double strand break repair nuclease","termid":"PBO:0059180"}


id: GO:0001659
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A homeostatic process in which an organism modulates its internal body temperature.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multicellular organismal-level homeostasis","termid":"GO:0048871"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"temperature homeostasis","secondary_identifiers":["Wikipedia:Thermoregulation"],"synonyms":[{"name":"thermoregulation","type":"exact"}],"termid":"GO:0001659"}


id: PBO:0028477
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_galactose-specific_cell-cell_adhesion","termid":"PBO:0028477"}


id: PBO:0083887
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ferulic acid decarboxylase; involved in the decarboxylation of aromatic carboxylic acids such as phenylacrylic (cinnamic) acid, ferulic acid and coumaric acid and formation of the corresponding vinyl derivatives; overexpression of both Pad1p and Fdc1p increases decarboxylase activity due to the Pad1p-catalyzed formation of a diffusible cofactor required for Fdc1p activity; homolog of E. coli UbiD; GFP-fusion protein localizes to the cytoplasm in an HTP study","termid":"PBO:0083887"}


id: MONDO:0020753
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infectious disease causes by viruses in the subfamily Orthocoronavirinae (coronaviruses). In humans, coronaviruses cause respiratory tract infections that can be mild, such as some cases of the common cold (among other possible causes, predominantly rhinoviruses), and others that can be lethal, such as SARS, MERS, and COVID-19.","definition_xrefs":["Wikipedia:Coronavirus"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Coronaviridae infectious disease","termid":"MONDO:0005718"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Orthocoronavirinae infectious disease","secondary_identifiers":["DOID:0080599"],"synonyms":[{"name":"coronavirus infectious disease","type":"exact"}],"termid":"MONDO:0020753","xrefs":{"Monarch":{"xref_id":"0020753"}}}


id: PBO:0055348
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2777","termid":"PBO:0055348"}


id: PR:P31397
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- map3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P31397"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pheromone M-factor receptor (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3F10.10c","synonyms":[{"name":"Spom972h-map3","type":"exact"}],"termid":"PR:P31397"}


id: GO:1902159
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.","definition_xrefs":["GOC:TermGenie","PMID:11420311"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of monoatomic ion transmembrane transporter activity","termid":"GO:0032412"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"regulation of cyclic nucleotide-gated ion channel activity","synonyms":[{"name":"regulation of cyclic nucleotide activated ion channel activity","type":"exact"},{"name":"regulation of cyclic nucleotide gated ion channel activity","type":"exact"},{"name":"regulation of cyclic nucleotide-activated ion channel activity","type":"exact"}],"termid":"GO:1902159"}


id: GO:1900868
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of sarcinapterin.","definition_xrefs":["GOC:TermGenie","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tricarboxylic acid biosynthetic process","termid":"GO:0072351"},{"relation_name":"is_a","term_name":"sarcinapterin metabolic process","termid":"GO:1900867"},{"relation_name":"is_a","term_name":"methanopterin-containing compound biosynthetic process","termid":"GO:2001116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0042559"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0042559"],"is_obsolete":false,"name":"sarcinapterin biosynthetic process","synonyms":[{"name":"sarcinapterin anabolism","type":"exact"},{"name":"sarcinapterin biosynthesis","type":"exact"},{"name":"sarcinapterin formation","type":"exact"},{"name":"sarcinapterin synthesis","type":"exact"}],"termid":"GO:1900868"}


id: GO:0060001
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.","definition_xrefs":["GOC:dph","PMID:10519557"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microfilament motor activity","termid":"GO:0000146"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003774"}],"interesting_parent_ids":["GO:0003774","GO:0003674"],"is_obsolete":false,"name":"minus-end directed microfilament motor activity","synonyms":[{"name":"minus-end directed actin filament motor activity","type":"related"},{"name":"minus-end directed actin-filament motor activity","type":"exact"},{"name":"pointed-end directed actin-filament motor activity","type":"exact"}],"termid":"GO:0060001"}


id: MONDO:0030069
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hyper-IgE syndrome","termid":"MONDO:0018037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"hyper-IgE recurrent infection syndrome 5, autosomal recessive","secondary_identifiers":["MEDGEN:1716052","OMIM:618944","UMLS:C5394550"],"synonyms":[{"name":"HIES5","type":"exact"},{"name":"HYPER-IgE RECURRENT INFECTION SYNDROME 5, AUTOSOMAL RECESSIVE","type":"exact"},{"name":"hyper-IgE recurrent infection syndrome 5, autosomal recessive","type":"exact"}],"termid":"MONDO:0030069","xrefs":{"Monarch":{"xref_id":"0030069"}}}


id: PBO:0078977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ser (anticodon GCT) 4-2","termid":"PBO:0078977"}


id: PR:O94444
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 26S proteasome non-ATPase regulatory subunit 4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR10223:SF0","PRO:DNx","OMA:SCHPO01888"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"26S proteasome regulatory subunit rpn10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC637.10c","secondary_identifiers":["UniProtKB:O94444"],"synonyms":[{"name":"Spom972h-PSMD4","type":"exact"}],"termid":"PR:O94444"}


id: PBO:0070302
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY1 pseudogene 8","termid":"PBO:0070302"}


id: PBO:0073506
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SH2 domain containing 1B","termid":"PBO:0073506"}


id: GO:0010674
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.","definition_xrefs":["PMID:8618927","GOC:tb","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle (obsolete GO:0010674)","synonyms":[{"name":"activation of meiosis by negative regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"negative regulation of transcription from RNA polymerase II promoter, meiotic","type":"exact"},{"name":"positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter","type":"narrow"}],"termid":"GO:0010674"}


id: GO:0005935
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"site of polarized growth","termid":"GO:0030427"},{"relation_name":"part_of","term_name":"cellular bud","termid":"GO:0005933"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"cellular bud neck","termid":"GO:0005935"}


id: PBO:0071883
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPS3A pseudogene 21","termid":"PBO:0071883"}


id: GO:0097105
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.","definition_xrefs":["GOC:pr","GOC:sjp","GOC:BHF","PMID:18550748","PMID:15797875"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane assembly","termid":"GO:0071709"},{"relation_name":"is_a","term_name":"presynaptic membrane organization","termid":"GO:0097090"},{"relation_name":"part_of","term_name":"presynapse assembly","termid":"GO:0099054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0061024"],"is_obsolete":false,"name":"presynaptic membrane assembly","synonyms":[{"name":"pre-synaptic membrane assembly","type":"exact"}],"termid":"GO:0097105"}


id: PR:Q9P7K6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC21C3.19 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P7K6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SDO1-like protein C21C3.19 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC21C3.19","synonyms":[{"name":"Spom972h-SPBC21C3.19","type":"exact"}],"termid":"PR:Q9P7K6"}


id: MONDO:1011190
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Spinal stenosis that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spinal stenosis, non-human animal","termid":"MONDO:1010303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spinal stenosis, cattle","secondary_identifiers":["OMIA:000947-9913"],"termid":"MONDO:1011190","xrefs":{"Monarch":{"xref_id":"1011190"}}}


id: GO:0018132
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.","definition_xrefs":["RESID:AA0238","PMID:8895467"],"gene_count":0,"genotype_count":0,"name":"obsolete peptide cross-linking via L-cysteine oxazolecarboxylic acid (obsolete GO:0018132)","termid":"GO:0018132"}


id: GO:0004963
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with follicle-stimulating hormone to initiate a change in cell activity.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-hormone receptor activity","termid":"GO:0016500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"follicle-stimulating hormone receptor activity","synonyms":[{"name":"FSH receptor activity","type":"exact"},{"name":"follicle stimulating hormone receptor activity","type":"exact"}],"termid":"GO:0004963"}


id: PBO:0056284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotically associated long non coding RNA","termid":"PBO:0056284"}


id: MONDO:0016643
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of rare bone development disorders characterized by an array of abnormalities affecting the eyes, forehead, and nose, and linked to midfacial dysraphia. The clinical picture is highly variable, but the major findings include hypertelorism, a broad nasal root, a large and bifid nasal tip, and widow's peak. Occasionally, abnormalities can include accessory nasal tags, cleft lip, ocular abnormalities (coloboma, cataract, microphthalmia), conductive hearing loss, basal encephalocele and/or agenesis of the corpus callosum. Intellectual deficit is rare and more likely to occur in cases where hypertelorism is severe or where there is extra-cranial involvement.","definition_xrefs":["Orphanet:250"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"dysostosis","termid":"MONDO:0018234"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"frontonasal dysplasia","secondary_identifiers":["SCTID:86610004","MEDGEN:406292","UMLS:C1876203","DOID:0081044","GARD:2392","MESH:C538065","icd11.foundation:782645776","NORD:1165","OMIMPS:136760"],"synonyms":[{"name":"FND1","type":"narrow"},{"name":"frontonasal dysplasia 1","type":"narrow"},{"name":"median cleft face syndrome","type":"exact"},{"name":"median cleft syndrome","type":"related"}],"termid":"MONDO:0016643","xrefs":{"Monarch":{"xref_id":"0016643"}}}


id: GO:0022032
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.","definition_xrefs":["GOC:dph","GOC:jid","GO_REF:0000021","GOC:dgh","GOC:cls"],"direct_ancestors":[{"relation_name":"is_a","term_name":"telencephalon glial cell migration","termid":"GO:0022030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"telencephalon oligodendrocyte cell migration","termid":"GO:0022032"}


id: GO:0052898
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: H2O + N(1)-acetylspermidine + O2 = 1,3-diaminopropane + 4-acetamidobutanal + H2O2.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity (obsolete GO:0052898)","termid":"GO:0052898"}


id: MONDO:0009277
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive form of congenital glaucoma caused by mutation(s) in the CYP1B1 gene, encoding cytochrome P450 1B1.","definition_xrefs":["NCIT:C148260"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete hydrophthalmos (obsolete MONDO:0006788)","termid":"MONDO:0006788"},{"relation_name":"is_a","term_name":"CYP1B1-related glaucoma with or without anterior segment dysgenesis","termid":"MONDO:0800472"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"glaucoma 3A","secondary_identifiers":["GARD:18224","DOID:11211","Orphanet:98976","ICD9:743.21","MEDGEN:383912","UMLS:C1856439","OMIM:231300"],"synonyms":[{"name":"GLC3A","type":"related"},{"name":"Primary Congenital glaucoma 3A","type":"exact"},{"name":"buphthalmos","type":"broad"},{"name":"glaucoma 3, primary congenital, A","type":"related"},{"name":"glaucoma 3, primary congenital, type a","type":"exact"},{"name":"glaucoma 3A, primary open angle, congenital, juvenile, or adult onset","type":"exact"},{"name":"glaucoma, congenital","type":"related"},{"name":"glaucoma, primary open angle, adult-onset","type":"related"},{"name":"glaucoma, primary open angle, juvenile-onset","type":"related"},{"name":"simple buphthalmos","type":"exact"}],"termid":"MONDO:0009277","xrefs":{"Monarch":{"xref_id":"0009277"}}}


id: PBO:0004444
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NRDE-2 family protein (predicted)","termid":"PBO:0004444"}


id: GO:0002191
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.","definition_xrefs":["PMID:17284590","PMID:19604130"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic translational initiation","termid":"GO:0002183"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0002181"}],"interesting_parent_ids":["GO:0002181","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"cap-dependent translational initiation","termid":"GO:0002191"}


id: PBO:0049054
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 53, pseudogene","termid":"PBO:0049054"}


id: PBO:0109026
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3102","termid":"PBO:0109026"}


id: GO:0043041
data:
  {"annotated_genes":["SJAG_04031"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[93301],"is_not":false,"summary":null,"term":"GO:0043041"}]},"cv_name":"biological_process","definition":"Activation of an amino acid for incorporation into a peptide by a nonribosomal process.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid activation","termid":"GO:0043038"},{"relation_name":"part_of","term_name":"nonribosomal peptide biosynthetic process","termid":"GO:0019184"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04031":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0006520","GO:0008150"],"is_obsolete":false,"name":"amino acid activation for nonribosomal peptide biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"nonribosomal amino acid activation","type":"related"}],"termid":"GO:0043041","terms_by_termid":{"GO:0043041":null}}


id: GO:0098894
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.","definition_xrefs":["GOC:mf","GOC:autophagy"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extrinsic component of presynaptic membrane","termid":"GO:0098888"},{"relation_name":"part_of","term_name":"presynaptic endocytic zone membrane","termid":"GO:0098835"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005575","GO:0005886"],"is_obsolete":false,"name":"extrinsic component of presynaptic endocytic zone membrane","termid":"GO:0098894"}


id: MONDO:0006315
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete neoplastic medium-sized B-lymphocyte with basophilic cytoplasm (obsolete MONDO:0006315)","secondary_identifiers":["NCIT:C37005"],"termid":"MONDO:0006315","xrefs":{"Monarch":{"xref_id":"0006315"}}}


id: MONDO:0016803
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete unspecified inborn mitochondrial disorder (obsolete MONDO:0016803)","secondary_identifiers":["Orphanet:254837"],"synonyms":[{"name":"unspecified mitochondrial disorder","type":"exact"}],"termid":"MONDO:0016803","xrefs":{"Monarch":{"xref_id":"0016803"}}}


id: GO:1904784
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex.","definition_xrefs":["PMID:19124602","GO_REF:0000079","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"canonical inflammasome complex assembly","termid":"GO:0140632"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0065003","GO:0023052","GO:0044085"],"is_obsolete":false,"name":"NLRP1 inflammasome complex assembly","synonyms":[{"name":"NALP1 inflammasome complex assembly","type":"exact"},{"name":"NALP1 inflammasome complex formation","type":"exact"},{"name":"NLRP1 inflammasome complex formation","type":"exact"}],"termid":"GO:1904784"}


id: GO:0031723
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a CXCR4 chemokine receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"CXCR chemokine receptor binding","termid":"GO:0045236"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"CXCR4 chemokine receptor binding","synonyms":[{"name":"CXCR4 chemokine receptor ligand","type":"narrow"},{"name":"stromal cell-derived factor 1 receptor binding","type":"exact"}],"termid":"GO:0031723"}


id: FYPO:0001468
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases abnormally, or does not change, following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours.","definition_xrefs":["PMID:21811607","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered cellular calcium level","termid":"FYPO:0001462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abnormal steady-state intracellular calcium level following extracellular calcium stimulus","synonyms":[{"name":"abnormal increase in steady-state intracellular calcium level following extracellular calcium stimulus","type":"exact"},{"name":"abnormal increase in steady-state intracellular calcium level following extracellular calcium stimulus during vegetative growth","type":"exact"},{"name":"abnormal steady-state intracellular calcium level following extracellular calcium stimulus during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001468"}


id: PBO:0041410
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 6 open reading frame 226","termid":"PBO:0041410"}


id: PBO:0071222
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 63","termid":"PBO:0071222"}


id: MONDO:0030787
data:
  {"annotated_genes":["SJAG_03051"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86175],"is_not":false,"summary":null,"term":"MONDO:0030787"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03051":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 71","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5676963","OMIM:619831","DOID:0070570","MEDGEN:1801153"],"synonyms":[{"name":"SPGF71","type":"exact"},{"name":"spermatogenic failure 71","type":"exact"}],"termid":"MONDO:0030787","terms_by_termid":{"MONDO:0030787":null},"xrefs":{"Monarch":{"xref_id":"0030787"}}}


id: PBO:0066691
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of microtubule dynamics 2","termid":"PBO:0066691"}


id: GO:0048665
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell fate specification","termid":"GO:0001708"},{"relation_name":"part_of","term_name":"neuron fate commitment","termid":"GO:0048663"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neuron fate specification","termid":"GO:0048665"}


id: PBO:0039763
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenine phosphoribosyltransferase","termid":"PBO:0039763"}


id: PBO:0081740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNF670-ZNF695 readthrough (NMD candidate)","termid":"PBO:0081740"}


id: GO:0045189
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of CTGF, produced by human umbilical vein endothelial cells and by skin fibroblasts after activation with TGF-beta.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete connective tissue growth factor biosynthetic process (obsolete GO:0045189)","synonyms":[{"name":"CTGF biosynthesis","type":"exact"},{"name":"connective tissue growth factor anabolism","type":"exact"},{"name":"connective tissue growth factor biosynthesis","type":"exact"},{"name":"connective tissue growth factor formation","type":"exact"},{"name":"connective tissue growth factor synthesis","type":"exact"}],"termid":"GO:0045189"}


id: GO:0015577
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.","definition_xrefs":["GOC:mtg_transport","GOC:ai","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate transmembrane transporter activity","termid":"GO:0015144"},{"relation_name":"is_a","term_name":"polyol transmembrane transporter activity","termid":"GO:0015166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"galactitol transmembrane transporter activity","secondary_identifiers":["GO:0015588"],"synonyms":[{"name":"galactitol permease activity","type":"exact"}],"termid":"GO:0015577"}


id: MONDO:0008702
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Achondrogenesis type 2 (ACG2), a form of achondrogenesis, is a very rare and lethal skeletal dysplasia and part of the spectrum of type 2 collagen-related bone disorders, characterizedby severe micromelia, short neck with large head, small thorax, protuberant abdomen, underdeveloped lungs, distinctive facial features such as a prominent forehead, a small chin, a cleft palate (in some) and distinctive histological features of the cartilage.","definition_xrefs":["Orphanet:93296"],"direct_ancestors":[{"relation_name":"is_a","term_name":"achondrogenesis","termid":"MONDO:0019648"},{"relation_name":"is_a","term_name":"type 2 collagenopathy","termid":"MONDO:0022800"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"achondrogenesis type II","secondary_identifiers":["MESH:C536017","UMLS:C0220685","GARD:8713","NANDO:2201345","OMIM:200610","DOID:0080056","MEDGEN:66315"],"synonyms":[{"name":"ACG2","type":"related"},{"name":"achondrogenesis type 2","type":"related"},{"name":"achondrogenesis type II","type":"exact"},{"name":"achondrogenesis, Langer-Saldino type","type":"exact"},{"name":"achondrogenesis, type 2","type":"related"},{"name":"achondrogenesis, type IB","type":"related"},{"name":"achondrogenesis, type IB, formerly","type":"related"},{"name":"achondrogenesis, type II","type":"related"},{"name":"achondrogenesis, type II or hypochondrogenesis","type":"exact"},{"name":"chondrogenesis imperfecta","type":"related"},{"name":"hypochondrogenesis","type":"related"}],"termid":"MONDO:0008702","xrefs":{"Monarch":{"xref_id":"0008702"}}}


id: MONDO:1011612
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Von Willebrand disease that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Von Willebrand disease, non-human animal","termid":"MONDO:1011411"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Von Willebrand disease, dog","secondary_identifiers":["OMIA:001056-9615"],"termid":"MONDO:1011612","xrefs":{"Monarch":{"xref_id":"1011612"}}}


id: PBO:0039118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AIDA pseudogene 1","termid":"PBO:0039118"}


id: MONDO:0004126
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the thyroid gland. This category includes Hashimoto thyroiditis, Riedel thyroiditis, acute thyroiditis, subacute thyroiditis, and radiation-induced thyroiditis.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thyroid gland disorder","termid":"MONDO:0003240"},{"relation_name":"is_a","term_name":"inflammatory disease","termid":"MONDO:0021166"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thyroiditis","secondary_identifiers":["HP:0100646","DOID:7166","SCTID:82119001","UMLS:C0040147","icd11.foundation:587793334","ICD9:245.9","MEDGEN:21548","ICD9:245","NCIT:C26894","MESH:D013966"],"synonyms":[{"name":"inflammation of thyroid gland","type":"exact"},{"name":"thyroid gland inflammation","type":"exact"},{"name":"thyroiditis","type":"exact"},{"name":"thyroiditis (disease)","type":"exact"}],"termid":"MONDO:0004126","xrefs":{"Monarch":{"xref_id":"0004126"}}}


id: PBO:0078051
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 41","termid":"PBO:0078051"}


id: GO:0102089
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete dehydroscoulerine synthase activity (obsolete GO:0102089)","termid":"GO:0102089"}


id: FYPO:0007907
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal when a cell is subject to amino acid starvation.","definition_xrefs":["PMID:34805795nPomBase:val"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein phosphorylation during vegetative growth","termid":"FYPO:0001038"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0002274","FYPO:0002494","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased protein phosphorylation during amino acid starvation","termid":"FYPO:0007907"}


id: PBO:0039590
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anoctamin 7 like 1 (pseudogene)","termid":"PBO:0039590"}


id: GO:0044433
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete cytoplasmic vesicle part (obsolete GO:0044433)","termid":"GO:0044433"}


id: GO:0004154
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide.","definition_xrefs":["PMID:1745247","PMID:38786926","PMID:6815189","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor","termid":"GO:0016647"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"dihydropterin oxidase activity","secondary_identifiers":["MetaCyc:RXN-15269"],"termid":"GO:0004154"}


id: GO:0071963
data:
  {"annotated_genes":["SJAG_02536","SJAG_03581","SJAG_01799","SJAG_04461","SJAG_02022","SJAG_04509","SJAG_00610","SJAG_00596","SJAG_03637","SJAG_04522","SJAG_00333","SJAG_04666","SJAG_00661","SJAG_00236","SJAG_00845"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[103706],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061246"},{"annotations":[106771,115719],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:2000784"},{"annotations":[92937,104518,102879,99361],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:2000247"},{"annotations":[102880],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:0061361"},{"annotations":[117910,99364,93782,103710,104521,112184,94858,90344],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:2000100"},{"annotations":[87112,102027,91627],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:2000769"}]},"cv_name":"biological_process","definition":"Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment or maintenance of cell polarity","termid":"GO:0007163"},{"relation_name":"is_a","term_name":"regulation of cell shape","termid":"GO:0008360"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00236":null,"SJAG_00333":null,"SJAG_00596":null,"SJAG_00610":null,"SJAG_00661":null,"SJAG_00845":null,"SJAG_01799":null,"SJAG_02022":null,"SJAG_02536":null,"SJAG_03581":null,"SJAG_03637":null,"SJAG_04461":null,"SJAG_04509":null,"SJAG_04522":null,"SJAG_04666":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007163"}],"interesting_parent_ids":["GO:0007163","GO:0008150"],"is_obsolete":false,"name":"establishment or maintenance of cell polarity regulating cell shape","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0071963","terms_by_termid":{"GO:0061246":null,"GO:0061361":null,"GO:2000100":null,"GO:2000247":null,"GO:2000769":null,"GO:2000784":null}}


id: GO:0031459
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).","definition_xrefs":["RHEA:32783","GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino-acid betaine transmembrane transporter activity","termid":"GO:0015199"},{"relation_name":"is_a","term_name":"ABC-type quaternary ammonium compound transporting activity","termid":"GO:0015418"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"ABC-type glycine betaine transporter activity","secondary_identifiers":["MetaCyc:TRANS-RXN-283"],"synonyms":[{"name":"ATP-dependent glycine betaine transporter activity","type":"exact"},{"name":"ATPase-coupled glycine betaine transporter activity","type":"related"},{"name":"N-trimethylglycine-transporting ATPase activity","type":"exact"},{"name":"glycine betaine ABC transporter","type":"narrow"},{"name":"glycine betaine-transporting ATPase activity","type":"related"}],"termid":"GO:0031459"}


id: FYPO:0006275
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which pyknosis, the form of chromatin condensation typical of cell death by apoptosis, occurs at a greater frequency than normal when the population in which the cell is found is in stationary phase.","definition_xrefs":["PomBase:mah","PMID:18653539","GO:0030263"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal apoptotic process","termid":"FYPO:0000629"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"increased pyknosis during stationary phase","synonyms":[{"name":"increased apoptotic chromosome condensation during stationary phase","type":"exact"}],"termid":"FYPO:0006275"}


id: GO:0045159
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.","definition_xrefs":["GOC:mah","PMID:27697842"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myosin binding","termid":"GO:0017022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0008092"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0008092","GO:0003674"],"is_obsolete":false,"name":"myosin II binding","termid":"GO:0045159"}


id: MONDO:1010707
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Porphyria cutanea tarda that occurs in sheep.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"porphyria cutanea tarda, non-human animal","termid":"MONDO:1010102"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"porphyria cutanea tarda, sheep","secondary_identifiers":["OMIA:001176-9940"],"termid":"MONDO:1010707","xrefs":{"Monarch":{"xref_id":"1010707"}}}


id: PBO:0072114
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S14 pseudogene 3","termid":"PBO:0072114"}


id: PBO:0002563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"electron transfer flavoprotein alpha subunit (predicted)","termid":"PBO:0002563"}


id: MONDO:0015841
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Partial septate uterus is a rare, non-syndromic uterovaginal malformation characterized by a uterus that has a longitudinal septum which extends from the uterine fundus and does not reach the internal cervical os (variable lengths and widths may be observed). Although frequently asymptomatic, an increased risk of poor reproductive outcome has been observed. Urinary tract abnormalities are very rarely associated.","definition_xrefs":["Orphanet:180129"],"direct_ancestors":[{"relation_name":"is_a","term_name":"septate uterus","termid":"MONDO:0015839"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial septate uterus","secondary_identifiers":["SCTID:5364006","MEDGEN:539894","GARD:20182","UMLS:C0266401"],"synonyms":[{"name":"subtotal septate uterus","type":"exact"},{"name":"uterus subseptus","type":"exact"}],"termid":"MONDO:0015841","xrefs":{"Monarch":{"xref_id":"0015841"}}}


id: PBO:0066336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RCC1 like","termid":"PBO:0066336"}


id: PBO:0056160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"macroH2A.1 histone","termid":"PBO:0056160"}


id: FYPO:0000087
data:
  {"alleles_by_uniquename":{"SJAG_04312:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04312","name":"pka1delta","uniquename":"SJAG_04312:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[118618],"is_not":false,"summary":null,"term":"FYPO:0000087"}]},"cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrogen peroxide. Cells stop growing (and may die) at a concentration of hydrogen peroxide that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitive to DNA damaging agents","termid":"FYPO:0000266"},{"relation_name":"is_a","term_name":"sensitive to oxidative stress","termid":"FYPO:0000726"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04312":null},"genotype_count":1,"genotypes_by_uniquename":{"pka1delta":{"display_name":"pka1delta","display_uniquename":"pka1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04312:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000003","FYPO:0002683","FYPO:0000139"],"is_obsolete":false,"name":"sensitive to hydrogen peroxide","references_by_uniquename":{"PMID:27678009":null},"single_locus_annotated_genes":["SJAG_04312"],"single_locus_genotype_uniquenames":["pka1delta"],"synonyms":[{"name":"hypersensitive to hydrogen peroxide","type":"exact"},{"name":"sensitive to H2O2","type":"exact"},{"name":"sensitive to hydrogen peroxide during mitotic cell cycle","type":"related"},{"name":"sensitive to hydrogen peroxide during vegetative growth","type":"exact"}],"termid":"FYPO:0000087","terms_by_termid":{"FYPO:0000087":null}}


id: PBO:0074179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 38 member 2","termid":"PBO:0074179"}


id: GO:0006031
data:
  {"annotated_genes":["SJAG_00978","SJAG_03723","SJAG_00442","SJAG_04868","SJAG_01453","SJAG_04728","SJAG_02845"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70387,87404,87743,87915,101964,103831,109199],"is_not":false,"summary":null,"term":"GO:0006031"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoglycan biosynthetic process","termid":"GO:0006023"},{"relation_name":"is_a","term_name":"chitin metabolic process","termid":"GO:0006030"},{"relation_name":"is_a","term_name":"glucosamine-containing compound biosynthetic process","termid":"GO:1901073"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00442":null,"SJAG_00978":null,"SJAG_01453":null,"SJAG_02845":null,"SJAG_03723":null,"SJAG_04728":null,"SJAG_04868":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chitin biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:PWY-6981"],"synonyms":[{"name":"beta-1,4-linked N-acetylglucosamine biosynthesis","type":"exact"},{"name":"beta-1,4-linked N-acetylglucosamine biosynthetic process","type":"exact"},{"name":"chitin anabolism","type":"exact"},{"name":"chitin biosynthesis","type":"exact"},{"name":"chitin formation","type":"exact"},{"name":"chitin synthesis","type":"exact"}],"termid":"GO:0006031","terms_by_termid":{"GO:0006031":null}}


id: MONDO:1012271
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"thrombasthenia, non-human animal","termid":"MONDO:1011694"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombasthenia, domestic cat","secondary_identifiers":["OMIA:001000-9685"],"termid":"MONDO:1012271","xrefs":{"Monarch":{"xref_id":"1012271"}}}


id: FYPO:0005745
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transport phenotype in which the export of protein from the nucleus is abnormal. Export of all proteins or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nuclear transport","termid":"FYPO:0005573"},{"relation_name":"is_a","term_name":"abnormal protein transport","termid":"FYPO:0005744"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"abnormal protein export from nucleus","termid":"FYPO:0005745"}


id: PBO:0062555
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 10 subfamily A member 2","termid":"PBO:0062555"}


id: GO:1905099
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity.","definition_xrefs":["PMID:20484009","GOC:TermGenie","GO_REF:0000059"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of GTP binding","termid":"GO:1904426"},{"relation_name":"is_a","term_name":"regulation of guanyl-nucleotide exchange factor activity","termid":"GO:1905097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of guanyl-nucleotide exchange factor activity","synonyms":[{"name":"activation of GDP-dissociation stimulator activity","type":"narrow"},{"name":"activation of GDS","type":"narrow"},{"name":"activation of GEF","type":"narrow"},{"name":"activation of GNRP","type":"narrow"},{"name":"activation of guanyl-nucleotide exchange factor activity","type":"narrow"},{"name":"activation of guanyl-nucleotide release factor activity","type":"narrow"},{"name":"activation of guanyl-nucleotide releasing factor","type":"narrow"},{"name":"positive regulation of GDP-dissociation stimulator activity","type":"exact"},{"name":"positive regulation of GDS","type":"exact"},{"name":"positive regulation of GEF","type":"exact"},{"name":"positive regulation of GNRP","type":"narrow"},{"name":"positive regulation of guanyl-nucleotide release factor activity","type":"exact"},{"name":"positive regulation of guanyl-nucleotide releasing factor","type":"exact"},{"name":"up regulation of GDP-dissociation stimulator activity","type":"exact"},{"name":"up regulation of GDS","type":"exact"},{"name":"up regulation of GEF","type":"exact"},{"name":"up regulation of GNRP","type":"narrow"},{"name":"up regulation of guanyl-nucleotide exchange factor activity","type":"exact"},{"name":"up regulation of guanyl-nucleotide release factor activity","type":"exact"},{"name":"up regulation of guanyl-nucleotide releasing factor","type":"exact"},{"name":"up-regulation of GDP-dissociation stimulator activity","type":"exact"},{"name":"up-regulation of GDS","type":"exact"},{"name":"up-regulation of GEF","type":"exact"},{"name":"up-regulation of GNRP","type":"narrow"},{"name":"up-regulation of guanyl-nucleotide exchange factor activity","type":"exact"},{"name":"up-regulation of guanyl-nucleotide release factor activity","type":"exact"},{"name":"up-regulation of guanyl-nucleotide releasing factor","type":"exact"},{"name":"upregulation of GDP-dissociation stimulator activity","type":"exact"},{"name":"upregulation of GDS","type":"exact"},{"name":"upregulation of GEF","type":"exact"},{"name":"upregulation of GNRP","type":"narrow"},{"name":"upregulation of guanyl-nucleotide exchange factor activity","type":"exact"},{"name":"upregulation of guanyl-nucleotide release factor activity","type":"exact"},{"name":"upregulation of guanyl-nucleotide releasing factor","type":"exact"}],"termid":"GO:1905099"}


id: MONDO:0100220
data:
  {"annotated_genes":["SJAG_03626"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85090],"is_not":false,"summary":null,"term":"MONDO:0100220"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Rajab interstitial lung disease with brain calcifications","termid":"MONDO:0100214"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03626":null},"genotype_count":0,"is_obsolete":false,"name":"Rajab interstitial lung disease with brain calcifications 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5436603","OMIM:619013","MEDGEN:1770895","GARD:18298"],"synonyms":[{"name":"RAJAB INTERSTITIAL LUNG DISEASE WITH BRAIN CALCIFICATIONS 2","type":"exact"},{"name":"RILDBC2","type":"exact"}],"termid":"MONDO:0100220","terms_by_termid":{"MONDO:0100220":null},"xrefs":{"Monarch":{"xref_id":"0100220"}}}


id: FYPO:0003878
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to monensin. Cells stop growing (and may die) at a concentration of monensin that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002683","FYPO:0001985","FYPO:0000003","FYPO:0000139"],"is_obsolete":false,"name":"sensitive to monensin","synonyms":[{"name":"hypersensitive to monensin","type":"exact"},{"name":"sensitive to monensin A","type":"narrow"},{"name":"sensitive to monensin during mitotic cell cycle","type":"related"},{"name":"sensitive to monensin during vegetative growth","type":"exact"}],"termid":"FYPO:0003878"}


id: MONDO:0015164
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent is a subgroup of therapy-related myeloid neoplasms (t-MN), associated with a treatment of an unrelated neoplastic or autoimmune disease with cytotoxic agents, like cyclophosphamid, platins, melphalan and others. The neoplastic cells typically harbor unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. It usually presents with multilineage dysplasia and cytopenias 5-10 years after exposure, with symptoms related to the degree of bone marrow failure and the corresponding cytopenia (fatigue, bleeding and bruising, recurrent infections, bone pain).","definition_xrefs":["Orphanet:102379"],"direct_ancestors":[{"relation_name":"is_a","term_name":"therapy related acute myeloid leukemia and myelodysplastic syndrome","termid":"MONDO:0019457"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570","MONDO:0004992"],"is_obsolete":false,"name":"acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent","secondary_identifiers":["UMLS:C1332234","GARD:19835","icd11.foundation:1401970160","MEDGEN:233970"],"synonyms":[{"name":"AML and myelodysplastic syndromes related to alkylating agent","type":"exact"}],"termid":"MONDO:0015164","xrefs":{"Monarch":{"xref_id":"0015164"}}}


id: GO:0070601
data:
  {"annotated_genes":["SJAG_04259","SJAG_00600","SJAG_03418","SJAG_00229","SJAG_03989","SJAG_01082","SJAG_03926","SJAG_04126","SJAG_01805","SJAG_01601","SJAG_03681","SJAG_04699"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[112360,112913,106980,100459,115035,100980,103673,113632,98321,92993],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1990813"},{"annotations":[69820,90130],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051754"},{"annotations":[90132,98323],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071962"}]},"cv_name":"biological_process","definition":"The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sister chromatid cohesion","termid":"GO:0007062"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00229":null,"SJAG_00600":null,"SJAG_01082":null,"SJAG_01601":null,"SJAG_01805":null,"SJAG_03418":null,"SJAG_03681":null,"SJAG_03926":null,"SJAG_03989":null,"SJAG_04126":null,"SJAG_04259":null,"SJAG_04699":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"centromeric sister chromatid cohesion","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"sister chromatid cohesion at centromere","type":"exact"}],"termid":"GO:0070601","terms_by_termid":{"GO:0051754":null,"GO:0071962":null,"GO:1990813":null}}


id: GO:0014735
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of muscle atrophy.","definition_xrefs":["GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of muscle adaptation","termid":"GO:0043502"},{"relation_name":"regulates","term_name":"muscle atrophy","termid":"GO:0014889"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of muscle atrophy","termid":"GO:0014735"}


id: PBO:0036534
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleoprotein (RNP) complex Utp502 (predicted)","termid":"PBO:0036534"}


id: PBO:0031779
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_rate_of_endocytosis_during_vegetative_growth","termid":"PBO:0031779"}


id: PBO:0043715
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 6B1 pseudogene 3","termid":"PBO:0043715"}


id: PBO:0108698
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ArfGEF Syt22","termid":"PBO:0108698"}


id: PBO:0059156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metallophosphoesterase 1 pseudogene 1","termid":"PBO:0059156"}


id: PBO:0071478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L32 pseudogene 19","termid":"PBO:0071478"}


id: MONDO:0005064
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete infectious meningitis (obsolete MONDO:0005064)","termid":"MONDO:0005064","xrefs":{"Monarch":{"xref_id":"0005064"}}}


id: PBO:0027174
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_G418","termid":"PBO:0027174"}


id: FYPO:0001239
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tert-butyl hydroperoxide (t-BOOH, TBHP).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0002060","FYPO:0000257","FYPO:0000003","FYPO:0000139","FYPO:0002058"],"is_obsolete":false,"name":"normal growth on tert-butyl hydroperoxide","synonyms":[{"name":"normal cell population growth in presence of tert-butyl hydroperoxide","type":"exact"},{"name":"normal cell population growth on 2-methyl-prop-2-yl-hydroperoxide","type":"exact"},{"name":"normal cell population growth on tert-butyl hydroperoxide","type":"exact"},{"name":"normal cellular response to tert-butyl hydroperoxide","type":"related"},{"name":"normal growth on TBHP","type":"exact"},{"name":"normal growth on t-BOOH","type":"exact"},{"name":"normal vegetative cell population growth on tert-butyl hydroperoxide","type":"exact"}],"termid":"FYPO:0001239"}


id: GO:1903844
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.","definition_xrefs":["GO_REF:0000058","GOC:rph","PMID:22269326","GOC:TermGenie","GOC:BHF","GOC:BHF_miRNA"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular response to growth factor stimulus","termid":"GO:0090287"},{"relation_name":"regulates","term_name":"cellular response to transforming growth factor beta stimulus","termid":"GO:0071560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cellular response to transforming growth factor beta stimulus","synonyms":[{"name":"regulation of cellular response to TGF-beta stimulus","type":"exact"},{"name":"regulation of cellular response to TGFbeta stimulus","type":"exact"}],"termid":"GO:1903844"}


id: MONDO:0005662
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infection by parasites of the genus balantidium. The presence of Balantidium in the large intestine leads to diarrhea; dysentery; and occasionally ulcer.","definition_xrefs":["MESH:D001447"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protozoa infectious disease","termid":"MONDO:0002428"},{"relation_name":"is_a","term_name":"Ciliophora infectious disease","termid":"MONDO:0005704"},{"relation_name":"is_a","term_name":"parasitic intestinal disorder","termid":"MONDO:0024270"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"balantidiasis","secondary_identifiers":["ICD9:007.0","SCTID:57725006","icd11.foundation:2090337975","Orphanet:1223","UMLS:C0004692","MedDRA:10004080","NORD:833","DOID:12386","ICD10CM:A07.0","NCIT:C84583","MEDGEN:2540","GARD:809","EFO:0007163"],"synonyms":[{"name":"B coli infection","type":"related"},{"name":"Balantidiases","type":"related"},{"name":"Balantidium coli infection","type":"related"},{"name":"Human balantidiasis","type":"related"},{"name":"balantidiosis","type":"exact"},{"name":"ciliary dysentery","type":"exact"},{"name":"large-intestinal infection with Balantidium coli","type":"related"}],"termid":"MONDO:0005662","xrefs":{"Monarch":{"xref_id":"0005662"}}}


id: PBO:0042850
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CFAP58 divergent transcript","termid":"PBO:0042850"}


id: PBO:0071958
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPS5 pseudogene 8","termid":"PBO:0071958"}


id: GO:0010389
data:
  {"annotated_genes":["SJAG_00526","SJAG_02858","SJAG_00600","SJAG_04287","SJAG_03942","SJAG_02723","SJAG_01084","SJAG_04394","SJAG_02342","SJAG_01205","SJAG_02332","SJAG_03126","SJAG_02266","SJAG_03048","SJAG_01901","SJAG_02771","SJAG_04140","SJAG_03309","SJAG_03160","SJAG_04486","SJAG_04597","SJAG_00256","SJAG_01805","SJAG_00216","SJAG_01076","SJAG_01010","SJAG_03695","SJAG_01146","SJAG_01680","SJAG_02563","SJAG_02392","SJAG_03026","SJAG_03854","SJAG_00640","SJAG_02592","SJAG_03486","SJAG_02098","SJAG_03927","SJAG_02074","SJAG_01429","SJAG_01605","SJAG_01855","SJAG_03592","SJAG_03073","SJAG_01837","SJAG_03602","SJAG_03067","SJAG_01000","SJAG_01118","SJAG_00214","SJAG_04332","SJAG_02576","SJAG_01044","SJAG_00117","SJAG_06592","SJAG_01456","SJAG_00883","SJAG_04280","SJAG_00364","SJAG_01873","SJAG_00318","SJAG_00082","SJAG_04671","SJAG_05373"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[101573,110346,111106],"is_not":false,"summary":null,"term":"GO:0010389"},{"annotations":[89200,99721,115138,93607,100619],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044878"},{"annotations":[98385,116235,102497,106993,116404,99722,98551,93138,88327,90636,93159,115936,108466,115195,105776,111175,91728],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033314"},{"annotations":[97628,115140,95047,93738],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031569"},{"annotations":[116840,93139,98553,90637,105777,113393,116149,89419,100237,90993,88328,99723,108467,110872,87757],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007095"},{"annotations":[113603,105808,110706,100182,92412,92761,92124,89201,111614,93567,113394,95049,103674,107724,115141,106171,110963,110577],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010972"},{"annotations":[87269,115807,98195,109490,90933,87260,107726,93609,100942,95522,110344,93740,102669,93570,91338,92997,115621,106396,97629],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010971"},{"annotations":[100569,87061],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905287"}]},"cv_name":"biological_process","definition":"Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.","definition_xrefs":["PMID:17329565","GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mitotic cell cycle phase transition","termid":"GO:1901990"},{"relation_name":"is_a","term_name":"regulation of cell cycle G2/M phase transition","termid":"GO:1902749"},{"relation_name":"regulates","term_name":"G2/M transition of mitotic cell cycle","termid":"GO:0000086"}],"gene_count":64,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_00117":null,"SJAG_00214":null,"SJAG_00216":null,"SJAG_00256":null,"SJAG_00318":null,"SJAG_00364":null,"SJAG_00526":null,"SJAG_00600":null,"SJAG_00640":null,"SJAG_00883":null,"SJAG_01000":null,"SJAG_01010":null,"SJAG_01044":null,"SJAG_01076":null,"SJAG_01084":null,"SJAG_01118":null,"SJAG_01146":null,"SJAG_01205":null,"SJAG_01429":null,"SJAG_01456":null,"SJAG_01605":null,"SJAG_01680":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_01855":null,"SJAG_01873":null,"SJAG_01901":null,"SJAG_02074":null,"SJAG_02098":null,"SJAG_02266":null,"SJAG_02332":null,"SJAG_02342":null,"SJAG_02392":null,"SJAG_02563":null,"SJAG_02576":null,"SJAG_02592":null,"SJAG_02723":null,"SJAG_02771":null,"SJAG_02858":null,"SJAG_03026":null,"SJAG_03048":null,"SJAG_03067":null,"SJAG_03073":null,"SJAG_03126":null,"SJAG_03160":null,"SJAG_03309":null,"SJAG_03486":null,"SJAG_03592":null,"SJAG_03602":null,"SJAG_03695":null,"SJAG_03854":null,"SJAG_03927":null,"SJAG_03942":null,"SJAG_04140":null,"SJAG_04280":null,"SJAG_04287":null,"SJAG_04332":null,"SJAG_04394":null,"SJAG_04486":null,"SJAG_04597":null,"SJAG_04671":null,"SJAG_05373":null,"SJAG_06592":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0044772"}],"interesting_parent_ids":["GO:0007049","GO:0008150","GO:0044772"],"is_obsolete":false,"name":"regulation of G2/M transition of mitotic cell cycle","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of mitotic entry","type":"exact"}],"termid":"GO:0010389","terms_by_termid":{"GO:0007095":null,"GO:0010389":null,"GO:0010971":null,"GO:0010972":null,"GO:0031569":null,"GO:0033314":null,"GO:0044878":null,"GO:1905287":null}}


id: PBO:0050101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 11","termid":"PBO:0050101"}


id: GO:0120174
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway.","definition_xrefs":["GOC:rn","PMID:29861160","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to stress","termid":"GO:0033554"},{"relation_name":"is_a","term_name":"proteasome-mediated ubiquitin-dependent protein catabolic process","termid":"GO:0043161"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0030163"},{"rel_name":"is_a","termid":"GO:0030163"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0030163","GO:0008150"],"is_obsolete":false,"name":"stress-induced homeostatically regulated protein degradation pathway","synonyms":[{"name":"SHRED pathway","type":"related"}],"termid":"GO:0120174"}


id: PBO:0046538
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group E member 1","termid":"PBO:0046538"}


id: FYPO:0003295
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amitrole.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002058","FYPO:0000257","FYPO:0002060","FYPO:0002057","FYPO:0000139"],"is_obsolete":false,"name":"normal growth on amitrole","synonyms":[{"name":"normal cell population growth in presence of amitrole","type":"exact"},{"name":"normal cell population growth on 3-AT","type":"exact"},{"name":"normal cell population growth on 3-amino-1,2,4-triazole","type":"exact"},{"name":"normal cell population growth on 3AT","type":"exact"},{"name":"normal cell population growth on amitrole","type":"exact"},{"name":"normal cellular response to amitrole","type":"related"},{"name":"normal vegetative cell population growth on amitrole","type":"exact"}],"termid":"FYPO:0003295"}


id: MONDO:0007456
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diarrhea, glucose-stimulated secretory, with common variable immunodeficiency","secondary_identifiers":["MESH:C565099","UMLS:C1852087","OMIM:125890","MEDGEN:377585"],"synonyms":[{"name":"diarrhea, glucose-stimulated secretory, with common variable immunodeficiency","type":"exact"}],"termid":"MONDO:0007456","xrefs":{"Monarch":{"xref_id":"0007456"}}}


id: PBO:0027589
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_duration_of_protein_tyrosine_phosphorylation_during_cellular_response_to_salt_stress","termid":"PBO:0027589"}


id: GO:1903131
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.","definition_xrefs":["GO_REF:0000086","PMID:24759906","GOC:TermGenie","CL:0000842"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte differentiation","termid":"GO:0002521"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mononuclear cell differentiation","termid":"GO:1903131"}


id: GO:0080173
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana.","definition_xrefs":["PMID:21123745"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell recognition","termid":"GO:0009988"},{"relation_name":"is_a","term_name":"cellular process involved in reproduction in multicellular organism","termid":"GO:0022412"},{"relation_name":"part_of","term_name":"fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm","termid":"GO:0061936"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"male-female gamete recognition during double fertilization forming a zygote and endosperm","synonyms":[{"name":"gamete recognition","type":"broad"},{"name":"male-female gamete recognition","type":"exact"}],"termid":"GO:0080173"}


id: PBO:0034762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"clathrin light chain Clc1","termid":"PBO:0034762"}


id: MONDO:1030005
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A somatic mosaic condition caused by a postzygotic mutation (c.1234 C>T p.Leu412Phe) in the SMO gene. Two overlapping clinical syndromes associated with this variant in SMO have been reported; Curry-Jones Syndrome (MIM:601707) and Happle-Tinschert Syndrome. The syndrome is characterized by cutaneous and skeletal manifestations such as linear hypo‐ or hyperpigmented lesions, basaloid follicular hamartomas, palmoplantar pitting, atrophoderma, hypertrichosis, polydactyly or syndactyly, rib anomalies (rudimentary ribs), and limb‐length anomalies. Craniofacial and dental abnormalities such as dysmorphic facies, macrocephaly, craniosynostosis, jaw tumors (ameloblastoma) have also been reported. Additional abnormalities impacting the gastrointestinal, cerebral, ophthalmic, and gonadal organs should also be considered. Some of these features include anal anomaly, colonic adenocarcinoma, severe constipation, myelofibrosis and smooth muscle hamartomas, malrotation, medulloblastoma, cerebral malformations, developmental delay, cataract, microphthalmia, coloboma, glaucoma, and cryptorchidism.","definition_xrefs":["PMID:27236920","PMID:30497210","PMID:32413283","PMID:7606318","PMID:31120550"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mosaic SMO syndrome","termid":"MONDO:1030005","xrefs":{"Monarch":{"xref_id":"1030005"}}}


id: PR:O59698
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A glycerol-3-phosphate transporter GlpT that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO02606"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized transporter C36.01c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC36.01c","secondary_identifiers":["UniProtKB:O59698"],"synonyms":[{"name":"Spom972h-glpT","type":"exact"}],"termid":"PR:O59698"}


id: PBO:0077987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ala (anticodon TGC) 9-1","termid":"PBO:0077987"}


id: MONDO:0033334
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete genetic nose and cavum anomaly (obsolete MONDO:0033334)","secondary_identifiers":["Orphanet:435606"],"termid":"MONDO:0033334","xrefs":{"Monarch":{"xref_id":"0033334"}}}


id: MONDO:0001320
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"scleral disorder","termid":"MONDO:0001269"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"ring staphyloma","secondary_identifiers":["DOID:11594","MEDGEN:509937","ICD9:379.15","SCTID:5299007","UMLS:C0155363","icd11.foundation:7248227"],"termid":"MONDO:0001320","xrefs":{"Monarch":{"xref_id":"0001320"}}}


id: PBO:0001331
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"essential function does not appear to reside in its role in the folding or retention of misfolded proteins","termid":"PBO:0001331"}


id: GO:0071573
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.","definition_xrefs":["GOC:vw","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-DNA complex assembly","termid":"GO:0065004"},{"relation_name":"part_of","term_name":"telomere organization","termid":"GO:0032200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0032200"}],"interesting_parent_ids":["GO:0008150","GO:0065003","GO:0032200","GO:0044085"],"is_obsolete":false,"name":"shelterin complex assembly","synonyms":[{"name":"Pot1 complex assembly","type":"related"},{"name":"Pot1-Tpz1 complex assembly","type":"related"},{"name":"shelterin complex formation","type":"related"},{"name":"telosome assembly","type":"exact"}],"termid":"GO:0071573"}


id: PBO:0030272
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_negative_regulation_of_mitotic_DNA_replication_initiation_resulting_in_partial_rereplication","termid":"PBO:0030272"}


id: PBO:0080455
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-set and transmembrane domain containing 2A","termid":"PBO:0080455"}


id: GO:0090045
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.","definition_xrefs":["GOC:dph","GOC:BHF","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of catalytic activity","termid":"GO:0043085"},{"relation_name":"is_a","term_name":"regulation of deacetylase activity","termid":"GO:0150065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of deacetylase activity","termid":"GO:0090045"}


id: PBO:0051090
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy joining 2","termid":"PBO:0051090"}


id: MONDO:0018162
data:
  {"annotated_genes":["SJAG_02791","SJAG_04449","SJAG_02313"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84706],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009736"},{"annotations":[86103],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014466"},{"annotations":[86145],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011152"},{"annotations":[85748],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012596"},{"annotations":[85168],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013531"}]},"cv_name":"mondo","definition":"Serine-deficiency syndrome is a very rare infantile-onset potentially treatable neurometabolic disorder characterized clinically by microcephaly, neurodevelopmental disorders and seizures. Three serine-deficiency syndromes have been described: 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, 3-phosphoserine phosphatase (3-PSP) deficiency, and phosphoserine aminotransferase deficiency.","definition_xrefs":["Orphanet:35705"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn serine deficiency","termid":"MONDO:0000421"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02313":null,"SJAG_02791":null,"SJAG_04449":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"neurometabolic disorder due to serine deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:18815","MEDGEN:1842451","UMLS:C5680148"],"synonyms":[{"name":"neurometabolic disorder due to serine deficiency","type":"exact"},{"name":"serine deficiency","type":"exact"}],"termid":"MONDO:0018162","terms_by_termid":{"MONDO:0009736":null,"MONDO:0011152":null,"MONDO:0012596":null,"MONDO:0013531":null,"MONDO:0014466":null},"xrefs":{"Monarch":{"xref_id":"0018162"}}}


id: PBO:0072630
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger and SPRY domain containing 1","termid":"PBO:0072630"}


id: GO:0050253
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.","definition_xrefs":["RHEA:21508"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016788","GO:0003824","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"retinyl-palmitate esterase activity","secondary_identifiers":["Reactome:R-HSA-2404133","Reactome:R-HSA-975594","Reactome:R-HSA-8848355","Reactome:R-HSA-975593","MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN"],"synonyms":[{"name":"retinyl ester hydrolase activity","type":"related"},{"name":"retinyl palmitate hydrolase activity","type":"related"},{"name":"retinyl palmitate hydrolyase activity","type":"related"},{"name":"retinyl-palmitate palmitohydrolase activity","type":"related"}],"termid":"GO:0050253"}


id: PBO:0031611
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-delayed_onset_of_vacuolar_transport","termid":"PBO:0031611"}


id: PBO:0063567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidase B","termid":"PBO:0063567"}


id: SO:0000273
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A tRNA sequence that has a valine anticodon, and a 3' valine binding region.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"valine_tRNA_primary_transcript","termid":"SO:0000230"},{"relation_name":"is_a","term_name":"tRNA","termid":"SO:0000253"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"valyl_tRNA","synonyms":[{"name":"valyl tRNA","type":"exact"},{"name":"valyl-transfer RNA","type":"related"},{"name":"valyl-transfer ribonucleic acid","type":"exact"}],"termid":"SO:0000273"}


id: GO:0009644
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to light intensity","termid":"GO:0009642"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to high light intensity","termid":"GO:0009644"}


id: GO:0070487
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The adhesion of one monocyte to one or more other monocytes via adhesion molecules.","definition_xrefs":["GOC:sl","PMID:12972508"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte aggregation","termid":"GO:0070486"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"monocyte aggregation","synonyms":[{"name":"mononuclear phagocyte aggregation","type":"exact"}],"termid":"GO:0070487"}


id: PBO:0043381
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"clustered mitochondria homolog pseudogene 11","termid":"PBO:0043381"}


id: PBO:0061609
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear distribution C, dynein complex regulator","termid":"PBO:0061609"}


id: PBO:0064075
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 109","termid":"PBO:0064075"}


id: FYPO:0002018
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable mitotic spindle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic spindle","termid":"FYPO:0000338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000120"},{"rel_name":"is_a","termid":"FYPO:0002399"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0001320","FYPO:0000054","FYPO:0005447","FYPO:0000120","FYPO:0002399"],"is_obsolete":false,"name":"mitotic spindle absent from cell","synonyms":[{"name":"absent mitotic spindle","type":"exact"},{"name":"mitotic spindle absent from cell during vegetative growth","type":"exact"},{"name":"spindle absent from cell during mitotic cell cycle","type":"related"}],"termid":"FYPO:0002018"}


id: GO:0005254
data:
  {"annotated_genes":["SJAG_01168"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[110807],"is_not":false,"summary":null,"term":"GO:0005254"}]},"cv_name":"molecular_function","definition":"Enables the energy-independent facilitated diffusion of a chloride ion through a transmembrane aqueous pore or channel.","definition_xrefs":["GOC:mtg_transport","GOC:pr","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monoatomic anion channel activity","termid":"GO:0005253"},{"relation_name":"is_a","term_name":"chloride transmembrane transporter activity","termid":"GO:0015108"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01168":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"chloride channel activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-2744349","Reactome:R-HSA-975449","Reactome:R-HSA-427570","Reactome:R-HSA-2684901","Reactome:R-HSA-2744361","Reactome:R-HSA-9712204","Reactome:R-HSA-975340","Reactome:R-HSA-2744242","Reactome:R-HSA-9659568"],"termid":"GO:0005254","terms_by_termid":{"GO:0005254":null}}


id: MONDO:0014820
data:
  {"annotated_genes":["SJAG_02656"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85056],"is_not":false,"summary":null,"term":"MONDO:0014820"}]},"cv_name":"mondo","definition":"Any mitochondrial DNA depletion syndrome in which the cause of the disease is a mutation in the OPA1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial DNA depletion syndrome","termid":"MONDO:0018158"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02656":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial DNA depletion syndrome 14 (cardioencephalomyopathic type)","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:903789","DOID:0080336","UMLS:C4225163","OMIM:616896"],"synonyms":[{"name":"MTDPS14","type":"exact"},{"name":"OPA1 mitochondrial DNA depletion syndrome","type":"exact"},{"name":"mitochondrial DNA depletion syndrome 14 (cardioencephalomyopathic type)","type":"exact"},{"name":"mitochondrial DNA depletion syndrome 14 (cardioencephalomyopathic type); MTDPS14","type":"exact"},{"name":"mitochondrial DNA depletion syndrome 14 (encephalocardiomyopathic type)","type":"exact"},{"name":"mitochondrial DNA depletion syndrome caused by mutation in OPA1","type":"exact"}],"termid":"MONDO:0014820","terms_by_termid":{"MONDO:0014820":null},"xrefs":{"Monarch":{"xref_id":"0014820"}}}


id: FYPO:0002363
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone acetylation during vegetative growth","termid":"FYPO:0000332"},{"relation_name":"is_a","term_name":"abnormal histone H3 acetylation during vegetative growth","termid":"FYPO:0002361"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0002494"],"is_obsolete":false,"name":"increased histone H3 acetylation during vegetative growth","synonyms":[{"name":"increased histone H3 acetylation during mitotic cell cycle","type":"related"}],"termid":"FYPO:0002363"}


id: PBO:0070739
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L10a pseudogene 9","termid":"PBO:0070739"}


id: PBO:0034335
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-obsolete_has_direct_output_(obsolete_RO:0002402)","termid":"PBO:0034335"}


id: SO:0000343
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region of sequence, aligned to another sequence with some statistical significance, using an algorithm such as BLAST or SIM4.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"experimental_feature","termid":"SO:0001410"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"match","termid":"SO:0000343"}


id: PBO:0080296
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 60 pseudogene","termid":"PBO:0080296"}


id: MONDO:0019033
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cutis verticis gyrata (CVG) is a progressive cutaneous disorder predominantly affecting males and characterized by hypertrophy and thickening of the skin of the scalp forming convoluted furrows with deep, tender, and cerebriform cutaneous folds. Hair is usually normal in the furrows and sparse on the folds. CG can be isolated (essential CVG) or associated with other abnormalities such as intellectual deficit, epilepsy, cataract, blindness, and deafness (non essential CVG).","definition_xrefs":["Orphanet:671"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dermis disorder","termid":"MONDO:0021154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"primary cutis verticis gyrata","secondary_identifiers":["GARD:1643","SCTID:51603000","icd11.foundation:71926572","MEDGEN:78095","ICD9:757.39","UMLS:C0263417"],"synonyms":[{"name":"cutis verticis gyrata","type":"exact"}],"termid":"MONDO:0019033","xrefs":{"Monarch":{"xref_id":"0019033"}}}


id: PBO:0059685
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 51","termid":"PBO:0059685"}


id: MONDO:0019113
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Benign paroxysmal torticollis of infancy (BPTI) is a rare functional disorder characterized by recurrent episodes of torticollic posturing of the head (inclination or tilting of the head to one side) in healthy children.","definition_xrefs":["Orphanet:71518"],"direct_ancestors":[{"relation_name":"is_a","term_name":"paroxysmal dystonia","termid":"MONDO:0016058"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"benign paroxysmal torticollis of infancy","secondary_identifiers":["icd11.foundation:545726308","GARD:18913","UMLS:C3494934","MEDGEN:782128","SCTID:719521002"],"termid":"MONDO:0019113","xrefs":{"Monarch":{"xref_id":"0019113"}}}


id: PBO:0089358
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pheromone p-factor receptor Mam2","termid":"PBO:0089358"}


id: PBO:0058023
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3973","termid":"PBO:0058023"}


id: PBO:0041709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calmodulin 2 pseudogene 4","termid":"PBO:0041709"}


id: PBO:0036150
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H4-K20_monomethylation_during_vegetative_growth","termid":"PBO:0036150"}


id: PBO:0004845
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.1.3.1","termid":"PBO:0004845"}


id: GO:1902789
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.","definition_xrefs":["GOC:TermGenie","GOC:mengo_curators","PMID:22328008","GO_REF:0000071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to alkane","termid":"GO:1902779"},{"relation_name":"is_a","term_name":"response to isooctane","termid":"GO:1902788"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to isooctane","termid":"GO:1902789"}


id: PATO:0001310
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A duration quality of a process inhering in a bearer by virtue of the bearer's duration of exhibition of thermal energy.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"duration","termid":"PATO:0001309"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"duration of temperature","termid":"PATO:0001310"}


id: MONDO:0019971
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"soft tissue neoplasm","termid":"MONDO:0006424"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"melanoma of soft tissue","secondary_identifiers":["Orphanet:97338","GARD:19367"],"synonyms":[{"name":"clear cell sarcoma of the tendons and aponeuroses","type":"exact"}],"termid":"MONDO:0019971","xrefs":{"Monarch":{"xref_id":"0019971"}}}


id: PBO:0061577
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurotrimin","termid":"PBO:0061577"}


id: PBO:0038538
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"abhydrolase domain containing 13","termid":"PBO:0038538"}


id: PBO:0070904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L17 pseudogene 12","termid":"PBO:0070904"}


id: GO:0030176
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.","definition_xrefs":["GOC:mah","GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete integral component of endoplasmic reticulum membrane (obsolete GO:0030176)","synonyms":[{"name":"ER integral membrane protein","type":"exact"},{"name":"integral to ER membrane","type":"exact"},{"name":"integral to endoplasmic reticulum membrane","type":"narrow"}],"termid":"GO:0030176"}


id: MONDO:0027749
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serpinopathy","secondary_identifiers":["Orphanet:250805","MEDGEN:1842372","GARD:20683","UMLS:C5680704"],"termid":"MONDO:0027749","xrefs":{"Monarch":{"xref_id":"0027749"}}}


id: PBO:0075274
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 18 pseudogene 27","termid":"PBO:0075274"}


id: FYPO:0002383
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 9 and 14 of histone H3 in regions of the genome that are actively transcribed occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah","PMID:23851719"],"gene_count":0,"genotype_count":0,"name":"obsolete increased histone H3-K9 and H3-K14 acetylation at centromere outer repeat during vegetative growth (obsolete FYPO:0002383)","synonyms":[{"name":"increased histone H3 acetylation (K9 and K14) at centromere outer repeat during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 and H3-K14 acetylation at centromere otr during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 and H3-K14 acetylation at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"increased histone H3-K9 and H3-K14 acetylation at centromeric outer repeat region during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 and H3-K14 acetylation at pericentric region during vegetative growth","type":"related"},{"name":"increased histone H3-K9 and H3-K14 acetylation at pericentromeric region during vegetative growth","type":"related"},{"name":"increased histone H3K9 and H3K14 acetylation at centromere outer repeat during vegetative growth","type":"exact"}],"termid":"FYPO:0002383"}


id: GO:0098543
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events in which a stimulus from another organism is received and converted into a molecular signal.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to other organism","termid":"GO:0051707"},{"relation_name":"is_a","term_name":"detection of external biotic stimulus","termid":"GO:0098581"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of other organism","secondary_identifiers":["GO:0051824"],"synonyms":[{"name":"recognition of other organism during symbiotic interaction","type":"narrow"},{"name":"recognition of other organism involved in symbiotic interaction","type":"narrow"}],"termid":"GO:0098543"}


id: GO:0033126
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of GTP catabolic process (obsolete GO:0033126)","synonyms":[{"name":"positive regulation of GTP breakdown","type":"exact"},{"name":"positive regulation of GTP catabolism","type":"exact"},{"name":"positive regulation of GTP degradation","type":"exact"}],"termid":"GO:0033126"}


id: PBO:0069441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 706, pseudogene","termid":"PBO:0069441"}


id: GO:0016527
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete brain-specific angiogenesis inhibitor activity (obsolete GO:0016527)","synonyms":[{"name":"brain-specific angiogenesis inhibitor activity","type":"exact"}],"termid":"GO:0016527"}


id: GO:0141027
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:20688909"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host cytoskeleton","termid":"GO:0052039"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host actin cytoskeleton","synonyms":[{"name":"disruption by symbiont of actin cytoskeleton","type":"related"},{"name":"modification by symbiont of host actin cytoskeleton","type":"related"},{"name":"perturbation by symbiont of host actin cytoskeleton","type":"exact"}],"termid":"GO:0141027"}


id: PBO:0090759
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CENP-A chaperone, NASP family, Sim3","termid":"PBO:0090759"}


id: PBO:0066343
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of chromosome condensation 2 pseudogene 5","termid":"PBO:0066343"}


id: PBO:0077717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transportin 1 pseudogene 3","termid":"PBO:0077717"}


id: PBO:0013438
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pombe FLocculin","termid":"PBO:0013438"}


id: PBO:0028501
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_UDP-galactose_transmembrane_transport","termid":"PBO:0028501"}


id: GO:1900509
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of pentose catabolic process to ethanol (obsolete GO:1900509)","synonyms":[{"name":"regulation of pentose catabolism to ethanol","type":"exact"}],"termid":"GO:1900509"}


id: GO:0007618
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.","definition_xrefs":["GOC:jl","ISBN:0387520546"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multi-organism reproductive process","termid":"GO:0044703"},{"relation_name":"part_of","term_name":"sexual reproduction","termid":"GO:0019953"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mating","termid":"GO:0007618"}


id: MONDO:1011982
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"vision disorder, non-human animal","termid":"MONDO:1011367"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rod-cone dysplasia, non-human animal","secondary_identifiers":["OMIA:000881"],"termid":"MONDO:1011982","xrefs":{"Monarch":{"xref_id":"1011982"}}}


id: MONDO:0005099
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Intracranial hemorrhage into the subarachnoid space.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brain disorder","termid":"MONDO:0005560"},{"relation_name":"is_a","term_name":"neurovascular disorder","termid":"MONDO:0043218"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"subarachnoid hemorrhage","secondary_identifiers":["UMLS:C0038525","HP:0002138","EFO:0000713","ICD9:430","MESH:D013345","SCTID:21454007","MEDGEN:11625"],"synonyms":[{"name":"subarachnoid haemorrhage (disease)","type":"exact"},{"name":"subarachnoid hemorrhage","type":"exact"},{"name":"subarachnoid hemorrhage (disease)","type":"exact"}],"termid":"MONDO:0005099","xrefs":{"Monarch":{"xref_id":"0005099"}}}


id: GO:0047901
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: formyl-CoA + H2O = CoA + formate + H+.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete formyl-CoA hydrolase activity (obsolete GO:0047901)","synonyms":[{"name":"formyl coenzyme A hydrolase activity","type":"related"}],"termid":"GO:0047901"}


id: PBO:0002529
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ABC transporter Ybt1","termid":"PBO:0002529"}


id: PBO:0113281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Polo-like kinase required for mitotic exit; regulates mitotic spindle assembly, nuclear shape, and protein localization to the nucleolus and SPBs; controls targeting and activation of Rho1p at the division site via Rho1p-GEFs; role in adaptation to DNA damage promotes genome instability during replicative senescence; regulates meiotic commitment, spindle assembly, chiasmata formation, recombination intermediate resolution and SC disassembly; human homologs PLK1 and PLK3 complement cdc5 mutants","termid":"PBO:0113281"}


id: PBO:0060419
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-acetylated alpha-linked acidic dipeptidase 2","termid":"PBO:0060419"}


id: GO:0022890
data:
  {"annotated_genes":["SJAG_01669","SJAG_03406","SJAG_01090","SJAG_04028","SJAG_02877","SJAG_02532","SJAG_01803","SJAG_07003","SJAG_04955","SJAG_03595","SJAG_01490","SJAG_01078","SJAG_04731","SJAG_00211","SJAG_02023","SJAG_04506","SJAG_01119","SJAG_03850","SJAG_00057","SJAG_02646","SJAG_02322","SJAG_04136","SJAG_04185","SJAG_00836","SJAG_02564","SJAG_05629","SJAG_01639","SJAG_04867","SJAG_00133","SJAG_02782","SJAG_02779","SJAG_03490","SJAG_04260","SJAG_07006","SJAG_02105","SJAG_01190","SJAG_04673","SJAG_02019","SJAG_04668","SJAG_01007","SJAG_04905","SJAG_02399","SJAG_03401","SJAG_04698","SJAG_03337","SJAG_01493","SJAG_03528","SJAG_MIT09","SJAG_02883","SJAG_01447","SJAG_00222","SJAG_04830","SJAG_02578","SJAG_04167","SJAG_MIT37","SJAG_03820","SJAG_03606","SJAG_03079","SJAG_MIT13","SJAG_05204","SJAG_00136","SJAG_01397","SJAG_04152","SJAG_05294","SJAG_04675","SJAG_04015","SJAG_00438","SJAG_01400","SJAG_02968","SJAG_03114","SJAG_MIT04","SJAG_01913","SJAG_01355","SJAG_02473","SJAG_02598","SJAG_00985","SJAG_01129","SJAG_04246","SJAG_05229","SJAG_00601","SJAG_03925","SJAG_01471","SJAG_07007","SJAG_00516","SJAG_01353","SJAG_01541","SJAG_04258","SJAG_04068","SJAG_01077","SJAG_04737","SJAG_MIT20","SJAG_MIT15","SJAG_00755","SJAG_01990","SJAG_01406","SJAG_03516","SJAG_00212","SJAG_04616","SJAG_02958","SJAG_04122","SJAG_02504","SJAG_00542","SJAG_01817","SJAG_02780","SJAG_00328","SJAG_04096","SJAG_02484","SJAG_03960","SJAG_03608","SJAG_MIT03","SJAG_00915","SJAG_00976","SJAG_04471"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[107820],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015410"},{"annotations":[111482],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140679"},{"annotations":[98448,118126],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008519"},{"annotations":[94525],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015086"},{"annotations":[116514,94880,91607,113572],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005262"},{"annotations":[108522],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015085"},{"annotations":[114698,90407,89913,97528],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015369"},{"annotations":[72485,109790,91692,113303,116337,113309,102161,75709],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005351"},{"annotations":[87154,61695,100669,113725],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005375"},{"annotations":[118175,88432,113360,87411,115953,91151,114592,118153,118174,118202,113791,107437,118203],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004129"},{"annotations":[102975,99677],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015093"},{"annotations":[98823],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008331"},{"annotations":[116341],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005358"},{"annotations":[91652],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061840"},{"annotations":[115133],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044750"},{"annotations":[96193,88722],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140107"},{"annotations":[99864],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034216"},{"annotations":[103352],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000006"},{"annotations":[97275,112347,112922],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005381"},{"annotations":[106744,113767,89428,56778,106474],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015095"},{"annotations":[100843],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015366"},{"annotations":[94967],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005364"},{"annotations":[102976,94526,89914],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005384"},{"annotations":[90408],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010486"},{"annotations":[91774,97240],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005366"},{"annotations":[111992],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008137"},{"annotations":[100818,107824],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005388"},{"annotations":[107014],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043682"},{"annotations":[107015],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140581"},{"annotations":[111485],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008556"},{"annotations":[111486],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008900"},{"annotations":[86917,86916,112905],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008553"},{"annotations":[111487],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008554"},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the transfer of inorganic cations from one side of a membrane to the other. 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id: PBO:0081228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger MYND-type containing 8","termid":"PBO:0081228"}


id: GO:0000012
data:
  {"annotated_genes":["SJAG_02680","SJAG_04410"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92898,114817],"is_not":false,"summary":null,"term":"GO:0000012"}]},"cv_name":"biological_process","definition":"The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.","definition_xrefs":["PMID:18626472"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA repair","termid":"GO:0006281"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02680":null,"SJAG_04410":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006281","GO:0006259"],"is_obsolete":false,"name":"single strand break repair","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0000012","terms_by_termid":{"GO:0000012":null}}


id: MONDO:0033365
data:
  {"annotated_genes":["SJAG_02576","SJAG_02266"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84479,84480],"is_not":false,"summary":null,"term":"MONDO:0033365"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02266":null,"SJAG_02576":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0005027","MONDO:0700092"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 56","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4540034","MEDGEN:1621755","DOID:0080282","OMIM:617665"],"synonyms":[{"name":"DEE56","type":"exact"},{"name":"EIEE56","type":"exact"},{"name":"developmental and epileptic encephalopathy 56","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 56","type":"exact"},{"name":"infantile epileptic encephalopathy 56","type":"exact"}],"termid":"MONDO:0033365","terms_by_termid":{"MONDO:0033365":null},"xrefs":{"Monarch":{"xref_id":"0033365"}}}


id: PBO:0035722
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_processing_during_vegetative_growth","termid":"PBO:0035722"}


id: MONDO:1010549
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Diprosopus that occurs in sheep.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diprosopus, non-human animal","termid":"MONDO:1010045"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diprosopus, sheep","secondary_identifiers":["OMIA:000290-9940"],"termid":"MONDO:1010549","xrefs":{"Monarch":{"xref_id":"1010549"}}}


id: MONDO:0859351
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  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"obesity and hypopigmentation","secondary_identifiers":["OMIM:620195","UMLS:C5774289","MEDGEN:1824062"],"termid":"MONDO:0859351","xrefs":{"Monarch":{"xref_id":"0859351"}}}


id: PBO:0063874
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol glycan anchor biosynthesis class F","termid":"PBO:0063874"}


id: MONDO:0009979
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Reticular dystrophy of the retinal pigment epithelium is a patterned dystrophy of the retinal pigment epithelium, of progressive course, characterized by the presence of a bilateral hyperpigmented reticular pattern resembling a fishnet with knots, resulting in a slowly progressive loss of vision that often only becomes apparent in old age. Reticular dystrophy of the retinal pigment epithelium is sometimes associated with scleral staphyloma, choroidal neovascularization, convergent strabismus, spherophakia with myopia and luxated lenses, and partial atrophy of the iris.","definition_xrefs":["Orphanet:99002"],"direct_ancestors":[{"relation_name":"is_a","term_name":"patterned dystrophy of the retinal pigment epithelium","termid":"MONDO:0018973"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"reticular dystrophy of the retinal pigment epithelium","secondary_identifiers":["GARD:16891","MESH:C564844","SCTID:723502001","UMLS:C1867332","OMIM:179840","ICD10CM:H35.5","icd11.foundation:878593681","MESH:C566721","MEDGEN:356753"],"synonyms":[{"name":"reticular dystrophy of retinal pigment epithelium","type":"exact"},{"name":"retinal dystrophy, reticular pigmentary, of POSTERIOR POLE","type":"related"}],"termid":"MONDO:0009979","xrefs":{"Monarch":{"xref_id":"0009979"}}}


id: MONDO:0008360
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete radioulnar synostosis (obsolete MONDO:0008360)","synonyms":[{"name":"obsolete radioulnar synostosis (disease)","type":"exact"}],"termid":"MONDO:0008360","xrefs":{"Monarch":{"xref_id":"0008360"}}}


id: MOD:01980
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-arginine residue to N4-glycosyl-arginine.","definition_xrefs":["PubMed:15279557","PubMed:8521968","RESID:AA0327","Unimod:41#R","PubMed:9536051"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-glycosylated residue","termid":"MOD:00006"},{"relation_name":"is_a","term_name":"modified L-arginine residue","termid":"MOD:00902"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"omega-N-glycosyl-L-arginine","synonyms":[{"name":"(2S)-2-amino-5-(beta-D-glucopyranosyl[imino(methylamino)methyl]amino)pentanoic acid","type":"exact"},{"name":"Hex","type":"related"},{"name":"Hexose","type":"related"},{"name":"NG-beta-D-glucosylarginine","type":"exact"},{"name":"omega-N-(beta-D-glucosyl)-L-arginine","type":"exact"},{"name":"omega-N-glucosyl-L-arginine","type":"exact"},{"name":"omega-N-glycosyl-L-arginine","type":"exact"}],"termid":"MOD:01980"}


id: GO:0002017
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.","definition_xrefs":["GOC:dph","GOC:tb","ISBN:0721643949"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal system process involved in regulation of blood volume","termid":"GO:0001977"},{"relation_name":"is_a","term_name":"regulation of systemic arterial blood pressure by hormone","termid":"GO:0001990"},{"relation_name":"is_a","term_name":"positive regulation of systemic arterial blood pressure","termid":"GO:0003084"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of blood volume by renal aldosterone","synonyms":[{"name":"aldosterone mediated control of body fluids","type":"related"},{"name":"aldosterone mediated regulation of blood volume","type":"exact"},{"name":"renal regulation of blood volume by aldosterone","type":"exact"}],"termid":"GO:0002017"}


id: FYPO:0004765
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cell population growth","termid":"FYPO:0000047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0000257","FYPO:0002057","FYPO:0000139","FYPO:0002058"],"is_obsolete":false,"name":"normal cell population growth during glucose starvation","synonyms":[{"name":"normal cell population growth during glucose depletion","type":"exact"},{"name":"normal cell population growth during glucose deprivation","type":"exact"},{"name":"normal cell population growth during glucose limitation","type":"related"},{"name":"normal growth during glucose starvation","type":"broad"}],"termid":"FYPO:0004765"}


id: GO:0097084
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscle cell development","termid":"GO:0055001"},{"relation_name":"part_of","term_name":"vascular associated smooth muscle cell differentiation","termid":"GO:0035886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"vascular associated smooth muscle cell development","synonyms":[{"name":"vascular smooth muscle cell development","type":"exact"}],"termid":"GO:0097084"}


id: GO:0043200
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.","definition_xrefs":["GOC:ef","GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to acid chemical","termid":"GO:0001101"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to amino acid","secondary_identifiers":["GO:0010237"],"synonyms":[{"name":"response to amino acid stimulus","type":"exact"}],"termid":"GO:0043200"}


id: MONDO:0002548
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A morphologic variant of schwannoma characterized by hypercellularity, Antoni A pattern, and the absence of well-formed Verocay bodies.","definition_xrefs":["NCIT:C4724"],"direct_ancestors":[{"relation_name":"is_a","term_name":"schwannoma","termid":"MONDO:0002546"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cellular schwannoma","secondary_identifiers":["SCTID:404026003","ICD9:215.9","ONCOTREE:CSCHW","MEDGEN:98124","UMLS:C0431124","DOID:3196"],"synonyms":[{"name":"CSCHW","type":"related"},{"name":"cellular neurilemmoma","type":"exact"},{"name":"cellular neurinoma","type":"exact"},{"name":"cellular schwannoma","type":"exact"}],"termid":"MONDO:0002548","xrefs":{"Monarch":{"xref_id":"0002548"}}}


id: PBO:0062218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily AN member 2 pseudogene","termid":"PBO:0062218"}


id: MONDO:0018132
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Congenital muscular alpha-dystroglycanopathy with brain and eye anomalies (MDDGA) is a cobblestone lissencephaly characterized by and considered to be pathognomonic of a continuum of recessive autosomal disorders with brain, ocular and muscular involvement. MDDGA includes Walker-Warburg syndrome, muscle-eye-brain disease, Fukuyama muscular and cerebral dystrophy and muscle eye brain disease with bilateral multicystic leukodystrophy.","definition_xrefs":["Orphanet:352687"],"gene_count":0,"genotype_count":0,"name":"obsolete congenital muscular alpha-dystroglycanopathy with brain and eye anomalies (obsolete MONDO:0018132)","secondary_identifiers":["DOID:0111229"],"synonyms":[{"name":"MDDGA","type":"exact"},{"name":"lissencephaly type 2 with muscular and ocular involvement","type":"exact"}],"termid":"MONDO:0018132","xrefs":{"Monarch":{"xref_id":"0018132"}}}


id: GO:0000170
data:
  {"annotated_genes":["SJAG_04913","SJAG_05311"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[91009,111676],"is_not":false,"summary":null,"term":"GO:0000170"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydroxylation of sphingolipid long chain bases.","definition_xrefs":["PMID:9556590"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity","termid":"GO:0016491"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04913":null,"SJAG_05311":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"sphingosine hydroxylase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-428260"],"termid":"GO:0000170","terms_by_termid":{"GO:0000170":null}}


id: PBO:0000598
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCR4-Not complex subunit Mot2 (predicted)","termid":"PBO:0000598"}


id: MONDO:0018355
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Prader-Willi-like syndrome","termid":"MONDO:0018354"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"SIM1-related Prader-Willi-like syndrome","secondary_identifiers":["Orphanet:398079","UMLS:C5680040","GARD:21642","MEDGEN:1802084"],"synonyms":[{"name":"PWS-like due to a point mutation","type":"related"},{"name":"PWS-like due to point mutation","type":"related"},{"name":"Prader-Willi-like syndrome due to a point mutation","type":"related"},{"name":"SIM1-related PWLS","type":"exact"}],"termid":"MONDO:0018355","xrefs":{"Monarch":{"xref_id":"0018355"}}}


id: PBO:0028304
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_phosphorylation_during_mitosis","termid":"PBO:0028304"}


id: PBO:0062396
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily E member 18 pseudogene","termid":"PBO:0062396"}


id: PBO:0070868
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPL14 pseudogene 6","termid":"PBO:0070868"}


id: PBO:0081142
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZFP42 zinc finger protein","termid":"PBO:0081142"}


id: GO:0075243
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sexual sporulation resulting in formation of a cellular spore","termid":"GO:0043935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"oospore formation","termid":"GO:0075243"}


id: MONDO:0016986
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital smooth muscle hamartoma (CSMH) is a rare cutaneous hamartomatous lesion most often located on the lumbosacral area or proximal limbs (but rarely on atypical areas such as scalp, eyelid or foot) and characterized by a disorganized proliferation of smooth muscle fibers of arrector pili presenting usually as a localized skin-colored or hyperpigmented plaque (up to 10 cm in diameter) with prominent vellus hairs (most common classic form) or less commonly by multiple skin-colored papules that can coalesce to form irregularly shaped plaques. With time, hyperpigmentation and vellus hairs usually diminish and neither malignant transformation nor associated systemic involvement has been reported.","definition_xrefs":["Orphanet:263435"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete rare skin tumor or hamartoma (obsolete MONDO:0019300)","termid":"MONDO:0019300"},{"relation_name":"is_a","term_name":"hamartoma","termid":"MONDO:0006499"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital smooth muscle hamartoma","secondary_identifiers":["GARD:20902","MEDGEN:590701","SCTID:239144007","ICD9:759.6","UMLS:C0406819"],"termid":"MONDO:0016986","xrefs":{"Monarch":{"xref_id":"0016986"}}}


id: PBO:0069336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 596, pseudogene","termid":"PBO:0069336"}


id: GO:0046952
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small molecule catabolic process","termid":"GO:0044282"},{"relation_name":"is_a","term_name":"fatty acid derivative catabolic process","termid":"GO:1901569"},{"relation_name":"is_a","term_name":"ketone body metabolic process","termid":"GO:1902224"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006091"}],"interesting_parent_ids":["GO:0044281","GO:0006091","GO:0006629","GO:0008150"],"is_obsolete":false,"name":"ketone body catabolic process","secondary_identifiers":["MetaCyc:PWY66-368"],"synonyms":[{"name":"ketolysis","type":"exact"},{"name":"ketone body breakdown","type":"exact"},{"name":"ketone body catabolism","type":"exact"},{"name":"ketone body degradation","type":"exact"},{"name":"utilization of ketone bodies","type":"exact"}],"termid":"GO:0046952"}


id: GO:0046225
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"toxin catabolic process","termid":"GO:0009407"},{"relation_name":"is_a","term_name":"peptide antibiotic catabolic process","termid":"GO:0030652"},{"relation_name":"is_a","term_name":"bacteriocin metabolic process","termid":"GO:0046224"},{"relation_name":"is_a","term_name":"detoxification of nitrogen compound","termid":"GO:0051410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0098754"},{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0098754","GO:0019748","GO:0008150","GO:0044248"],"is_obsolete":false,"name":"bacteriocin catabolic process","synonyms":[{"name":"bacteriocin breakdown","type":"exact"},{"name":"bacteriocin catabolism","type":"exact"},{"name":"bacteriocin degradation","type":"exact"}],"termid":"GO:0046225"}


id: MONDO:0009771
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Oculotrichodysplasia is characterized by retinitis pigmentosa, trichodysplasia, dental anomalies, and onychodysplasia. It has been described in two siblings (brother and sister) born to first cousin parents. Transmission appears to be autosomal recessive.","definition_xrefs":["Orphanet:2718"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"oculotrichodysplasia","secondary_identifiers":["GARD:16607","MEDGEN:340517","icd11.foundation:1202969811","OMIM:257960","SCTID:722062004","UMLS:C1850332","MESH:C564934"],"synonyms":[{"name":"Cecato de Lima-Pinheiro syndrome","type":"exact"},{"name":"OTD","type":"related"},{"name":"oculotrichodysplasia","type":"exact"}],"termid":"MONDO:0009771","xrefs":{"Monarch":{"xref_id":"0009771"}}}


id: PBO:0001198
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.8.1.4","termid":"PBO:0001198"}


id: GO:0070002
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidase activity","termid":"GO:0008233"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0008233"}],"interesting_parent_ids":["GO:0140096","GO:0008233","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"glutamic-type peptidase activity","termid":"GO:0070002"}


id: MONDO:0014293
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal dominant nonsyndromic deafness that has material basis in variation in the chromosome region 2p21-p12.","definition_xrefs":["PMID:19159392","DOID:0110582"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0019497"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 58","secondary_identifiers":["GARD:18139","OMIM:615654","UMLS:C3888210","MEDGEN:854817"],"synonyms":[{"name":"DFNA58","type":"narrow"},{"name":"autosomal dominant deafness 58","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 58","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 58","type":"narrow"},{"name":"deafness, autosomal dominant 58","type":"narrow"}],"termid":"MONDO:0014293","xrefs":{"Monarch":{"xref_id":"0014293"}}}


id: MONDO:0008552
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited blood coagulation disease characterized by autosomal dominant inheritance with macrothrombocytopenia, platelet anisocytosis, prolonged bleeding time but only mildly increased bleeding tendency that has material basis in heterozygous mutation in the ITGA2B gene on chromosome 17q21.31 or the ITGB3 gene on chromosome 17q21.32.","definition_xrefs":["PMID:21454453","PMID:18065693","PMID:9834222","DOID:0060691"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited bleeding disorder, platelet-type","termid":"MONDO:0000009"},{"relation_name":"is_a","term_name":"inherited blood coagulation disorder","termid":"MONDO:0021181"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"platelet-type bleeding disorder 16","secondary_identifiers":["MEDGEN:1781222","UMLS:C5442010","OMIM:187800","MESH:C566061"],"synonyms":[{"name":"BDPLT16","type":"related"},{"name":"Glanzmann thrombasthenia, autosomal dominant","type":"related"},{"name":"autosomal dominant Glanzmann thrombasthenia","type":"exact"},{"name":"autosomal dominant thrombasthenia of Glanzmann and Naegeli","type":"exact"},{"name":"bleeding disorder, platelet-type, 16","type":"related"},{"name":"bleeding disorder, platelet-type, 16, autosomal dominant","type":"exact"},{"name":"platelet-type bleeding disorder 16","type":"exact"},{"name":"thrombasthenia of Glanzmann and Naegeli, autosomal dominant","type":"related"}],"termid":"MONDO:0008552","xrefs":{"Monarch":{"xref_id":"0008552"}}}


id: PBO:0042901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complement factor H related 5","termid":"PBO:0042901"}


id: PBO:0045907
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EF-hand calcium binding domain 5","termid":"PBO:0045907"}


id: FYPO:0007990
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"Auxotrophy in which a cell is unable to synthesize isoleucine, and therefore requires isoleucine in the medium for vegetative cell growth.","definition_xrefs":["PMID:35325114","PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"auxotrophy","termid":"FYPO:0000128"},{"relation_name":"is_a","term_name":"abnormal cellular physical quality phenotype","termid":"FYPO:0004638"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"growth auxotrophic for isoleucine","synonyms":[{"name":"growth auxotrophic for isoleucine during mitotic cell cycle","type":"exact"},{"name":"growth auxotrophic for isoleucine during vegetative growth","type":"exact"},{"name":"isoleucine auxotrophy","type":"exact"}],"termid":"FYPO:0007990"}


id: PBO:0082806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of U4/U6-U5 snRNP complex; involved in second catalytic step of splicing; participates in spliceosomal assembly through its interaction with U1 snRNA; largest and most evolutionarily conserved protein of the spliceosome; mutations in human ortholog, PRPF8, cause Retinitis pigmentosa and missplicing in Myelodysplastic syndrome; mouse ortholog interacts with androgen receptor and may have a role in prostate cancer","termid":"PBO:0082806"}


id: PBO:0044432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 4 subfamily A member 26, pseudogene","termid":"PBO:0044432"}


id: MONDO:0017369
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autoinflammatory syndrome with immune deficiency (obsolete MONDO:0017369)","secondary_identifiers":["Orphanet:290839"],"termid":"MONDO:0017369","xrefs":{"Monarch":{"xref_id":"0017369"}}}


id: FYPO:0008190
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to chromatin at the centromere central core is increased during the meiotic prophase I.","direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization during meiosis","termid":"FYPO:0003549"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased protein localization to chromatin at centromere central core during meiotic prophase I","termid":"FYPO:0008190"}


id: GO:0098570
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"side of membrane","termid":"GO:0098552"},{"relation_name":"part_of","term_name":"plastid inner membrane","termid":"GO:0009528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"stromal side of plastid inner membrane","termid":"GO:0098570"}


id: GO:0106373
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD+ = 2-dehydro-3-deoxy-D-gluconate + 2 H+ + NADH.","definition_xrefs":["PMID:17175089","RHEA:67244"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aldehyde dehydrogenase (NAD+) activity","termid":"GO:0004029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"3-deoxyglucosone dehydrogenase activity","termid":"GO:0106373"}


id: PBO:0052386
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin family member 26A","termid":"PBO:0052386"}


id: GO:0030565
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule.","definition_xrefs":["PMID:11733745"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA pseudouridylation guide activity","termid":"GO:0030558"},{"relation_name":"is_a","term_name":"snRNA modification guide activity","termid":"GO:0030566"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003723","GO:0003674"],"is_obsolete":false,"name":"snRNA pseudouridylation guide activity","termid":"GO:0030565"}


id: MONDO:0012429
data:
  {"annotated_genes":["SJAG_00400"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84571],"is_not":false,"summary":null,"term":"MONDO:0012429"}]},"cv_name":"mondo","definition":"Any Aicardi-Goutieres syndrome in which the cause of the disease is a mutation in the RNASEH2B gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Aicardi-Goutieres syndrome","termid":"MONDO:0018866"},{"relation_name":"is_a","term_name":"RNASEH2B-related type 1 interferonopathy","termid":"MONDO:0700257"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00400":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005559","MONDO:0005046"],"is_obsolete":false,"name":"Aicardi-Goutieres syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:610181","UMLS:C3489724","NANDO:2200894","GARD:15472","MEDGEN:483677","NCIT:C165673"],"synonyms":[{"name":"AGS2","type":"related"},{"name":"Aicardi-Goutieres syndrome 2","type":"exact"},{"name":"Aicardi-Goutieres syndrome caused by mutation in RNASEH2B","type":"exact"},{"name":"Aicardi-Goutieres syndrome type 2","type":"exact"},{"name":"RNASEH2B Aicardi-Goutieres syndrome","type":"exact"},{"name":"RNASEH2B-related Aicardi-Goutieres syndrome","type":"related"}],"termid":"MONDO:0012429","terms_by_termid":{"MONDO:0012429":null},"xrefs":{"Monarch":{"xref_id":"0012429"}}}


id: PBO:0091576
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial protein adenylyltransferase SelO","termid":"PBO:0091576"}


id: MONDO:0968977
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"bilateral striopallidodentate calcinosis","termid":"MONDO:0008947"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0002039"],"is_obsolete":false,"name":"basal ganglia calcification, idiopathic, 9, autosomal recessive","secondary_identifiers":["OMIM:620786"],"termid":"MONDO:0968977","xrefs":{"Monarch":{"xref_id":"0968977"}}}


id: GO:0030449
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of complement activation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune effector process","termid":"GO:0002697"},{"relation_name":"is_a","term_name":"regulation of humoral immune response","termid":"GO:0002920"},{"relation_name":"regulates","term_name":"complement activation","termid":"GO:0006956"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of complement activation","synonyms":[{"name":"regulation of complement cascade","type":"exact"}],"termid":"GO:0030449"}


id: PBO:0049238
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRM7 antisense RNA 2","termid":"PBO:0049238"}


id: MONDO:0007297
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cerebral amyloid angiopathy characterized by ataxia, intention tremor, psychosis and dementia that has material basis in an autosomal dominant mutation of ITM2B on chromosome 13q14.2.","definition_xrefs":["DOID:0070030"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebral amyloid angiopathy","termid":"MONDO:0005620"},{"relation_name":"is_a","term_name":"ITM2B amyloidosis","termid":"MONDO:0018591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0021179"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005559","MONDO:0021179"],"is_obsolete":false,"name":"ADan amyloidosis","secondary_identifiers":["ICD10EXP:E85.4+","UMLS:C1861735","Orphanet:97346","MESH:C538209","ICD10EXP:I68.0*","GARD:9169","MEDGEN:396208","icd11.foundation:54507082","OMIM:117300"],"synonyms":[{"name":"FDD","type":"exact"},{"name":"HOOE","type":"exact"},{"name":"Heredopathia Ophthalmootoencephalica","type":"exact"},{"name":"ITM2B-related cerebral amyloid angiopathy 2","type":"related"},{"name":"cerebellar ataxia, cataract, deafness, and dementia Or psychosis","type":"exact"},{"name":"cerebellar ataxia, cataract, deafness, and dementia or psychosis","type":"related"},{"name":"cerebral amyloid angiopathy, ITM2B-RELATED, 2","type":"related"},{"name":"cerebral amyloid angiopathy, ITM2B-related, type 2","type":"exact"},{"name":"dementia, familial Danish","type":"related"},{"name":"familial Danish dementia","type":"exact"},{"name":"familial dementia, Danish type","type":"exact"}],"termid":"MONDO:0007297","xrefs":{"Monarch":{"xref_id":"0007297"}}}


id: MONDO:0016297
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetically highly heterogeneous otorhinolaryngologic disease, resulting from inner and/or middle ear or hearing nerve anomalies, typically characterized by bilateral, severe to profound hearing loss (mean sensorineural hearing impairment of 60 dB or more for 500-, 1,000-, and 2,000-Hz frequency tones in the better ear) which occurs before the onset of speech development and is not associated with visible external ear abnormalities or any other medical problems. It is usually nonprogressive and impedes oral language acquisition.","definition_xrefs":["Orphanet:216445"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nonsyndromic genetic hearing loss","termid":"MONDO:0019497"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0019497"],"is_obsolete":false,"name":"prelingual non-syndromic genetic hearing loss","secondary_identifiers":["SCTID:764098007","UMLS:C4706679","MEDGEN:1647959"],"synonyms":[{"name":"isolated prelingual genetic deafness","type":"narrow"},{"name":"prelingual non-syndromic genetic deafness","type":"narrow"},{"name":"prelingual non-syndromic genetic hearing loss","type":"exact"}],"termid":"MONDO:0016297","xrefs":{"Monarch":{"xref_id":"0016297"}}}


id: SO:0000971
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000971 DNA_replication_mode (obsolete SO:0000971)","synonyms":[{"name":"DNA replication mode","type":"exact"}],"termid":"SO:0000971"}


id: PBO:0060689
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-deacetylase and N-sulfotransferase 4","termid":"PBO:0060689"}


id: PBO:0085066
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-essential sumoylated protein of unknown function; similar to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus; TRI1 has a paralog, UAF30, that arose from the whole genome duplication","termid":"PBO:0085066"}


id: PBO:0028077
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-incomplete_mitotic_sister_chromatid_segregation","termid":"PBO:0028077"}


id: PBO:0054409
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1805","termid":"PBO:0054409"}


id: GO:0002490
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.","definition_xrefs":["GOC:add","PMID:15928678"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway","termid":"GO:0002488"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent","synonyms":[{"name":"TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway","type":"exact"},{"name":"TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway","type":"exact"},{"name":"endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent","type":"exact"}],"termid":"GO:0002490"}


id: PBO:0003224
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RecA family ATPase Rlp1","termid":"PBO:0003224"}


id: GO:0033288
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"quaternary ammonium group transmembrane transporter activity","termid":"GO:0015651"},{"relation_name":"is_a","term_name":"alcohol transmembrane transporter activity","termid":"GO:0015665"},{"relation_name":"is_a","term_name":"ATPase-coupled monocarboxylic acid transmembrane transporter activity","termid":"GO:0033285"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"ATPase-coupled hydroxyectoine transmembrane transporter activity","secondary_identifiers":["GO:0033287"],"synonyms":[{"name":"ATP-dependent hydroxyectoine transmembrane transporter activity","type":"exact"},{"name":"hydroxyectoine transmembrane transporter activity","type":"broad"},{"name":"hydroxyectoine-transporting ATPase activity","type":"exact"}],"termid":"GO:0033288"}


id: MONDO:1011580
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Osteogenesis imperfecta that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteogenesis imperfecta, non-human animal","termid":"MONDO:1011454"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteogenesis imperfecta, cattle","secondary_identifiers":["OMIA:000754-9913"],"termid":"MONDO:1011580","xrefs":{"Monarch":{"xref_id":"1011580"}}}


id: PBO:0091011
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH-dependent flavin oxidoreductase, implicated in cellular detoxification from family members","termid":"PBO:0091011"}


id: PR:Q9P7M5
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An H/ACA ribonucleoprotein complex subunit 3 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR13305:SF0","PRO:DNx","OMA:SCHPO00663"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H/ACA ribonucleoprotein complex subunit 3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAP27G11.13c","secondary_identifiers":["UniProtKB:Q9P7M5"],"synonyms":[{"name":"Spom972h-NOP10","type":"exact"},{"name":"nucleolar protein 10 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"nucleolar protein family A member 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"snoRNP protein nop10 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P7M5"}


id: MONDO:0001856
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"arterial disorder","termid":"MONDO:0000473"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"splenic artery aneurysm","secondary_identifiers":["ICD9:442.83","UMLS:C0155747","SCTID:70405009","DOID:14006","MEDGEN:510069"],"termid":"MONDO:0001856","xrefs":{"Monarch":{"xref_id":"0001856"}}}


id: PR:O13959
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An E3 ubiquitin-protein ligase RBX1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00632","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RING-box protein pip1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC23H4.18c","secondary_identifiers":["UniProtKB:O13959"],"synonyms":[{"name":"Pop-interacting protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RING-box protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-RBX1","type":"exact"}],"termid":"PR:O13959"}


id: PBO:0089475
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyridoxal phosphate-dependent transferase, unknown specificity, implicated in sulfur compound metabolism","termid":"PBO:0089475"}


id: MONDO:0013533
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hyperlipidemia due to hepatic triacylglycerol lipase deficiency is a rare, genetic hyperalphalipoproteinemia characterized by elevated plasma cholesterol and triglyceride (TG) levels with a marked TG enrichment of low- and high-density lipoproteins (HDL), presence of circulating beta-very low density lipoproteins and elevated HDL cholesterol levels, in the presence of a very low, or undetectable, postheparin plasma hepatic lipase activity. Premature atherosclerosis and/or coronary heart disease may be associated.","definition_xrefs":["Orphanet:140905"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hyperlipidemia","termid":"MONDO:0001336"},{"relation_name":"is_a","term_name":"hyperalphalipoproteinemia","termid":"MONDO:0015903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002525"],"is_obsolete":false,"name":"hyperlipidemia due to hepatic triglyceride lipase deficiency","secondary_identifiers":["GARD:12864","OMIM:614025","UMLS:C3151466","SCTID:720940008","MEDGEN:462816"],"synonyms":[{"name":"HL deficiency","type":"related"},{"name":"hepatic lipase deficiency","type":"related"},{"name":"hyperlipidemia due to HL deficiency","type":"exact"},{"name":"hyperlipidemia due to HTGL deficiency","type":"exact"},{"name":"hyperlipidemia due to hepatic lipase deficiency","type":"exact"},{"name":"hyperlipidemia due to hepatic triacylglycerol lipase deficiency","type":"related"},{"name":"lipc deficiency","type":"related"}],"termid":"MONDO:0013533","xrefs":{"Monarch":{"xref_id":"0013533"}}}


id: FYPO:0005663
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which re-entry into the mitotic cell cycle is abnormal after arrest resulting from heat shock.","definition_xrefs":["PMID:19546237","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular response to heat","termid":"FYPO:0000212"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0000298","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"abnormal re-entry into mitotic cell cycle after arrest in response to heat shock","synonyms":[{"name":"abnormal re-entry into mitotic cell cycle after arrest in response to heat shock during vegetative growth","type":"exact"},{"name":"abnormal re-entry into mitotic cell cycle after heat shock arrest","type":"exact"},{"name":"abnormal re-entry into mitotic cell cycle after heat shock-induced arrest","type":"exact"}],"termid":"FYPO:0005663"}


id: GO:0052633
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: cis-aconitate + H2O = isocitrate.","definition_xrefs":["GOC:pde","EC:4.2.1.3","MetaCyc:ACONITATEHYDR-RXN","GOC:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete isocitrate hydro-lyase (cis-aconitate-forming) activity (obsolete GO:0052633)","synonyms":[{"name":"aconitate hydratase activity","type":"broad"},{"name":"cis-aconitase activity","type":"broad"},{"name":"citrate hydro-lyase activity","type":"broad"},{"name":"citrate(isocitrate) hydro-lyase (cis-aconitate-forming)","type":"broad"},{"name":"citrate(isocitrate) hydro-lyase activity","type":"broad"}],"termid":"GO:0052633"}


id: PBO:0038776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activin A receptor type 1","termid":"PBO:0038776"}


id: GO:0052598
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + histamine + O2 = H2O2 + imidazole-4-acetaldehyde + NH4+.","definition_xrefs":["RHEA:25625"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diamine oxidase activity","termid":"GO:0052597"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"histamine oxidase activity","secondary_identifiers":["MetaCyc:RXN-9600","Reactome:R-HSA-5696131","KEGG_REACTION:R02150"],"synonyms":[{"name":"1H-Imidazole-4-ethanamine oxidase activity","type":"exact"},{"name":"1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) activity","type":"exact"},{"name":"histamine:oxygen oxidoreductase (deaminating) activity","type":"exact"}],"termid":"GO:0052598"}


id: GO:0050988
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.","definition_xrefs":["RESID:AA0363"],"gene_count":0,"genotype_count":0,"name":"obsolete N-terminal peptidyl-methionine carboxylation (obsolete GO:0050988)","termid":"GO:0050988"}


id: GO:0052419
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete metabolism by host of substance in symbiont (obsolete GO:0052419)","termid":"GO:0052419"}


id: PBO:0082217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha 6 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress","termid":"PBO:0082217"}


id: GO:0160114
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The structure which joins the B1 protofilament of the B tubule to the A10 and A11 protofilaments of the A tubule within an axonemal microtubule doublet.","definition_xrefs":["PMID:37295417","PMID:29430673","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"axonemal doublet microtubule","termid":"GO:0097545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737"],"is_obsolete":false,"name":"axonemal microtubule doublet outer junction","termid":"GO:0160114"}


id: GO:0019044
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral process","termid":"GO:0016032"},{"relation_name":"part_of","term_name":"viral latency","termid":"GO:0019042"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"maintenance of viral latency","secondary_identifiers":["GO:0075716","GO:0032360"],"synonyms":[{"name":"latent virus maintenance","type":"exact"},{"name":"prophage maintenance","type":"exact"},{"name":"provirus maintenance","type":"exact"}],"termid":"GO:0019044"}


id: MONDO:0010781
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"DNA repair disease","termid":"MONDO:0021190"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021190"}],"interesting_parent_ids":["MONDO:0021190","MONDO:0005066"],"is_obsolete":false,"name":"ataxia and polyneuropathy, adult-onset","secondary_identifiers":["OMIM:500010","UMLS:C1838916","MEDGEN:374087","DOID:0111750","MESH:C564020"],"termid":"MONDO:0010781","xrefs":{"Monarch":{"xref_id":"0010781"}}}


id: PBO:0028927
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-premature_protein_localization_to_medial_cortex_during_vegetative_growth","termid":"PBO:0028927"}


id: PBO:0068061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 366","termid":"PBO:0068061"}


id: MONDO:0013865
data:
  {"annotated_genes":["SJAG_04367"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85372],"is_not":false,"summary":null,"term":"MONDO:0013865"}]},"cv_name":"mondo","definition":"A rare mitochondrial oxidative phosphorylation disorder with complex I and IV deficiency characterized by lactic acidosis, hypotonia, hypertrophic cardiomyopathy and global developmental delay. Other clinical features include feeding difficulties, failure to thrive, seizures, optic atrophy and ataxia.","definition_xrefs":["Orphanet:314637"],"direct_ancestors":[{"relation_name":"is_a","term_name":"combined oxidative phosphorylation deficiency","termid":"MONDO:0000732"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04367":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0111480","OMIM:614702","GARD:17428","UMLS:C4749921","MEDGEN:1664257"],"synonyms":[{"name":"COXPD10","type":"exact"},{"name":"MTO1 combined oxidative phosphorylation deficiency","type":"exact"},{"name":"cardiomyopathy, infantile hypertrophic mitochondrial, and lactic acidosis","type":"related"},{"name":"combined oxidative phosphorylation defect type 10","type":"exact"},{"name":"combined oxidative phosphorylation deficiency 10","type":"related"},{"name":"combined oxidative phosphorylation deficiency caused by mutation in MTO1","type":"exact"},{"name":"combined oxidative phosphorylation deficiency type 10","type":"exact"},{"name":"mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency","type":"exact"}],"termid":"MONDO:0013865","terms_by_termid":{"MONDO:0013865":null},"xrefs":{"Monarch":{"xref_id":"0013865"}}}


id: PBO:0043125
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium and integrin binding family member 3","termid":"PBO:0043125"}


id: FYPO:0004806
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the cell wall is broken down to a lesser extent than in wild type at the site of cell-cell fusion during mating.","definition_xrefs":["PMID:25825517","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell wall disassembly at cell fusion site","termid":"FYPO:0006499"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0004805"},{"rel_name":"is_a","termid":"FYPO:0000301"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000301","FYPO:0004805","FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"incomplete cell wall disassembly at cell fusion site","synonyms":[{"name":"incomplete cell wall disassembly at cell fusion site during conjugation with cellular fusion","type":"exact"},{"name":"incomplete cell wall disassembly at cell fusion site during mating","type":"exact"},{"name":"incomplete cell wall disassembly at cell-cell fusion focus","type":"exact"},{"name":"incomplete cell wall disassembly at cell-cell fusion site","type":"exact"},{"name":"incomplete fungal-type cell wall disassembly at cell fusion site","type":"exact"},{"name":"incomplete fungal-type cell wall disassembly involved in conjugation with cellular fusion","type":"exact"}],"termid":"FYPO:0004806"}


id: GO:0099063
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.","definition_xrefs":["GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete integral component of postsynaptic recycling endosome membrane (obsolete GO:0099063)","termid":"GO:0099063"}


id: PBO:0088101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Urea amidolyase; contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation; protein abundance increases in response to DNA replication stress","termid":"PBO:0088101"}


id: PBO:0062702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 51 subfamily F member 1","termid":"PBO:0062702"}


id: MONDO:0015304
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Arachnoiditis (ARC) is a chronic inflammation of the arachnoid layer of the meninges, of which adhesive arachnoiditis is the most severe form, characterized by debilitating, intractable neurogenic back and limb pain and a range of other neurological problems.","definition_xrefs":["Orphanet:137817"],"direct_ancestors":[{"relation_name":"is_a","term_name":"infectious meningitis","termid":"MONDO:0004796"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arachnoiditis","secondary_identifiers":["SCTID:13980006","UMLS:C0003708","DOID:12156","GARD:5839","MESH:D001100","NORD:800","icd11.foundation:414817254","NCIT:C37913","MEDGEN:8175","MedDRA:10003074"],"synonyms":[{"name":"adhesive arachnoiditis","type":"exact"},{"name":"arachnoid mater inflammation","type":"exact"},{"name":"chronic arachnoiditis","type":"exact"},{"name":"inflammation of arachnoid mater","type":"exact"}],"termid":"MONDO:0015304","xrefs":{"Monarch":{"xref_id":"0015304"}}}


id: PBO:0060840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurofilament heavy pseudogene 1","termid":"PBO:0060840"}


id: PBO:0018048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZIP zinc transmembrane transporter Zrt1","termid":"PBO:0018048"}


id: FYPO:0005955
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the duration of the entire mitotic cell cycle is longer than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic cell cycle","termid":"FYPO:0000059"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000631","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"increased duration of mitotic cell cycle","synonyms":[{"name":"increased duration of mitotic cell cycle during vegetative growth","type":"exact"},{"name":"prolonged mitotic cell cycle","type":"exact"}],"termid":"FYPO:0005955"}


id: GO:0046000
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ecdysteroid secretion","termid":"GO:0007555"},{"relation_name":"is_a","term_name":"positive regulation of steroid hormone secretion","termid":"GO:2000833"},{"relation_name":"positively_regulates","term_name":"ecdysteroid secretion","termid":"GO:0045457"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of ecdysteroid secretion","synonyms":[{"name":"activation of ecdysteroid secretion","type":"narrow"},{"name":"stimulation of ecdysteroid secretion","type":"narrow"},{"name":"up regulation of ecdysteroid secretion","type":"exact"},{"name":"up-regulation of ecdysteroid secretion","type":"exact"},{"name":"upregulation of ecdysteroid secretion","type":"exact"}],"termid":"GO:0046000"}


id: PBO:0059864
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotubularin related protein 1","termid":"PBO:0059864"}


id: PR:Q09875
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- gms2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09875"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C12G12.12 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC12G12.12","synonyms":[{"name":"Spom972h-gms2","type":"exact"}],"termid":"PR:Q09875"}


id: PBO:0091336
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"The Bioneer strain appears to be incorrect (possibly Pab1 SPAC227.07c)","termid":"PBO:0091336"}


id: GO:0003385
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.","definition_xrefs":["GOC:dph","GOC:ascb_2009","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete cell-cell signaling involved in amphid sensory organ development (obsolete GO:0003385)","synonyms":[{"name":"cell-cell signalling involved in amphid sensory organ development","type":"exact"}],"termid":"GO:0003385"}


id: MONDO:0021960
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute or chronic inflammatory process affecting the ureter.","definition_xrefs":["NCIT:C78666"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ureteral disorder","termid":"MONDO:0001926"},{"relation_name":"is_a","term_name":"inflammatory disease","termid":"MONDO:0021166"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ureteritis","secondary_identifiers":["SCTID:111405003","UMLS:C0041959","icd11.foundation:817532938","MEDGEN:21777"],"synonyms":[{"name":"Inflammation of ureter","type":"related"},{"name":"Ureteritis","type":"related"},{"name":"ureteritis","type":"exact"}],"termid":"MONDO:0021960","xrefs":{"Monarch":{"xref_id":"0021960"}}}


id: PBO:0046902
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 25 member A","termid":"PBO:0046902"}


id: PR:Q10240
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug133 gene.","definition_xrefs":["UniProtKB:Q10240","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 133 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4G9.07","synonyms":[{"name":"Spom972h-mug133","type":"exact"}],"termid":"PR:Q10240"}


id: FYPO:0000774
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of pre-replicative complex assembly is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal pre-replicative complex assembly","termid":"FYPO:0000773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0000293","FYPO:0001985","FYPO:0001320","FYPO:0000631"],"is_obsolete":false,"name":"decreased pre-replicative complex assembly","synonyms":[{"name":"decreased pre-RC assembly","type":"exact"},{"name":"decreased pre-replicative complex assembly during mitotic cell cycle","type":"related"},{"name":"decreased pre-replicative complex assembly during vegetative growth","type":"exact"},{"name":"decreased pre-replicative complex formation","type":"exact"},{"name":"reduced pre-replicative complex assembly","type":"exact"}],"termid":"FYPO:0000774"}


id: PBO:0091605
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2 sequence errors 5368262TC->T 5368273 and G->GT would change amino acids PPIYGL to PPYTVL","termid":"PBO:0091605"}


id: MONDO:0010290
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"multinodular goiter","termid":"MONDO:0000334"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"goiter, multinodular 2","secondary_identifiers":["MEDGEN:337370","MESH:C564546","OMIM:300273","UMLS:C1846033"],"synonyms":[{"name":"MNG2","type":"exact"},{"name":"goiter, multinodular 2","type":"exact"},{"name":"goiter, multinodular, 2, X-linked dominant","type":"exact"}],"termid":"MONDO:0010290","xrefs":{"Monarch":{"xref_id":"0010290"}}}


id: GO:0000053
data:
  {"annotated_genes":["SJAG_04577"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[109609],"is_not":false,"summary":null,"term":"GO:0000053"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified amino acid metabolic process","termid":"GO:0006575"},{"relation_name":"is_a","term_name":"tricarboxylic acid metabolic process","termid":"GO:0072350"},{"relation_name":"is_a","term_name":"L-amino acid metabolic process","termid":"GO:0170033"},{"relation_name":"is_a","term_name":"non-proteinogenic amino acid metabolic process","termid":"GO:0170041"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04577":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"argininosuccinate metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"argininosuccinate metabolism","type":"exact"}],"termid":"GO:0000053","terms_by_termid":{"GO:0000053":null}}


id: PBO:0062775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 56 subfamily A member 3","termid":"PBO:0062775"}


id: PBO:0048322
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyceraldehyde 3 phosphate dehydrogenase pseudogene 33","termid":"PBO:0048322"}


id: GO:0140933
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.","definition_xrefs":["PMID:18820299","PMID:29483298"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrophosphatase activity","termid":"GO:0016462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity","secondary_identifiers":["RHEA:67484","EC:3.6.1.62"],"synonyms":[{"name":"m(7)GpppN-mRNA hydrolase activity","type":"exact"}],"termid":"GO:0140933"}


id: MONDO:0010924
data:
  {"annotated_genes":["SJAG_04362","SJAG_03804"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84707],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024554"},{"annotations":[86271],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013345"}]},"cv_name":"mondo","definition":"D-2-hydroxyglutaric aciduria (D-2-HGA) is a rare clinically variable neurological form of 2-hydroxyglutaric aciduria characterized biochemically by elevated D-2-hydroxyglutaric acid (D-2-HG) in the urine, plasma and cerebrospinal fluid.","definition_xrefs":["Orphanet:79315"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-hydroxyglutaric aciduria","termid":"MONDO:0016001"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03804":null,"SJAG_04362":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"D-2-hydroxyglutaric aciduria","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:237960000","UMLS:C1833429","DOID:0050575","MEDGEN:322192","GARD:5661","icd11.foundation:1170122566","OMIMPS:600721"],"synonyms":[{"name":"D-2-HGA","type":"exact"},{"name":"D-2-hydroxyglutaric acidemia","type":"exact"},{"name":"D-2-hydroxyglutaric aciduria 1","type":"related"},{"name":"D-2-hydroxyglutaric aciduria type 1","type":"exact"},{"name":"D2HA","type":"related"},{"name":"D2HGA","type":"related"}],"termid":"MONDO:0010924","terms_by_termid":{"MONDO:0013345":null,"MONDO:0024554":null},"xrefs":{"Monarch":{"xref_id":"0010924"}}}


id: PBO:0084854
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; mutation confers increased replicative lifespan","termid":"PBO:0084854"}


id: PBO:0064250
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pleckstrin","termid":"PBO:0064250"}


id: GO:1900048
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of hemostasis.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of biological process","termid":"GO:0048518"},{"relation_name":"is_a","term_name":"regulation of hemostasis","termid":"GO:1900046"},{"relation_name":"positively_regulates","term_name":"hemostasis","termid":"GO:0007599"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of hemostasis","synonyms":[{"name":"activation of hemostasis","type":"narrow"},{"name":"up regulation of hemostasis","type":"exact"},{"name":"up-regulation of hemostasis","type":"exact"},{"name":"upregulation of hemostasis","type":"exact"}],"termid":"GO:1900048"}


id: MOD:00105
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-serine residue to L-serine amide.","definition_xrefs":["PubMed:743209","RESID:AA0096"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C1-amidated residue","termid":"MOD:00883"},{"relation_name":"is_a","term_name":"modified L-serine residue","termid":"MOD:00916"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-serine amide","synonyms":[{"name":"(2S)-2-amino-3-hydroxypropanamide","type":"exact"},{"name":"L-serine amide","type":"exact"},{"name":"MOD_RES Serine amide","type":"exact"},{"name":"SerN","type":"exact"},{"name":"amidated L-serine","type":"exact"},{"name":"serinamide","type":"exact"}],"termid":"MOD:00105"}


id: PBO:0078566
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 50","termid":"PBO:0078566"}


id: PBO:0047966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, aphidicolin type, common, fra(X)(q27.2) D","termid":"PBO:0047966"}


id: FYPO:0000798
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to anisomycin. Cells stop growing (and may die) at a concentration of anisomycin that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000003","FYPO:0000139","FYPO:0001985","FYPO:0002683"],"is_obsolete":false,"name":"sensitive to anisomycin","synonyms":[{"name":"hypersensitive to anisomycin","type":"exact"},{"name":"sensitive to anisomycin during mitotic cell cycle","type":"related"},{"name":"sensitive to anisomycin during vegetative growth","type":"exact"}],"termid":"FYPO:0000798"}


id: PBO:0042146
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine ligand 4 like 2","termid":"PBO:0042146"}


id: MONDO:1011046
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nephrolithiasis that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nephrolithiasis, non-human animal","termid":"MONDO:1010260"},{"relation_name":"is_a","term_name":"urolithiasis, domestic cat","termid":"MONDO:1011080"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nephrolithiasis, domestic cat","secondary_identifiers":["OMIA:000709-9685"],"termid":"MONDO:1011046","xrefs":{"Monarch":{"xref_id":"1011046"}}}


id: GO:0030295
data:
  {"annotated_genes":["SJAG_03340","SJAG_00333","SJAG_02026","SJAG_04020","SJAG_05017","SJAG_03699","SJAG_03618","SJAG_01411","SJAG_01213","SJAG_03371","SJAG_00424","SJAG_04509","SJAG_02332","SJAG_04666","SJAG_02785","SJAG_03090","SJAG_03695","SJAG_01401","SJAG_02057","SJAG_00142","SJAG_03453","SJAG_04502","SJAG_02605","SJAG_03936","SJAG_02232","SJAG_00236","SJAG_04614","SJAG_01000","SJAG_04140","SJAG_00457","SJAG_01605","SJAG_00318","SJAG_04200","SJAG_00439"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[87046,88427,90514,98280,98281,98388,106303,108987,108988,109668,110579,111618,115457,116407,117911,118031,118032],"is_not":false,"summary":null,"term":"GO:0030295"},{"annotations":[91342],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019912"},{"annotations":[108027,104177,100810,116206,111226,110059,110348,112103],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061575"},{"annotations":[90394,112104,90065,109689,90393,117493,116408,90346,88442,88650,87119,91633,104287,99174,108421],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043539"}]},"cv_name":"molecular_function","definition":"Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activator activity","termid":"GO:0019209"},{"relation_name":"is_a","term_name":"protein kinase regulator activity","termid":"GO:0019887"}],"gene_count":34,"genes_by_uniquename":{"SJAG_00142":null,"SJAG_00236":null,"SJAG_00318":null,"SJAG_00333":null,"SJAG_00424":null,"SJAG_00439":null,"SJAG_00457":null,"SJAG_01000":null,"SJAG_01213":null,"SJAG_01401":null,"SJAG_01411":null,"SJAG_01605":null,"SJAG_02026":null,"SJAG_02057":null,"SJAG_02232":null,"SJAG_02332":null,"SJAG_02605":null,"SJAG_02785":null,"SJAG_03090":null,"SJAG_03340":null,"SJAG_03371":null,"SJAG_03453":null,"SJAG_03618":null,"SJAG_03695":null,"SJAG_03699":null,"SJAG_03936":null,"SJAG_04020":null,"SJAG_04140":null,"SJAG_04200":null,"SJAG_04502":null,"SJAG_04509":null,"SJAG_04614":null,"SJAG_04666":null,"SJAG_05017":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0140677"}],"interesting_parent_ids":["GO:0003674","GO:0030234","GO:0098772","GO:0140677"],"is_obsolete":false,"name":"protein kinase activator activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0030295","terms_by_termid":{"GO:0019912":null,"GO:0030295":null,"GO:0043539":null,"GO:0061575":null}}


id: FYPO:0006445
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation of one or more proteins involved in amino acid biosynthesis is decreased.","definition_xrefs":["PMID:29432178","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased translation","termid":"FYPO:0001798"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0006551","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased translation of amino acid biosynthesis proteins during vegetative growth","synonyms":[{"name":"decreased translation of amino acid biosynthesis genes during vegetative growth","type":"exact"},{"name":"decreased translation of amino acid biosynthesis mRNAs during vegetative growth","type":"exact"},{"name":"decreased translation of amino acid biosynthesis proteins during mitotic cell cycle","type":"related"},{"name":"reduced translation of amino acid biosynthesis proteins during vegetative growth","type":"exact"}],"termid":"FYPO:0006445"}


id: PBO:0051155
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 3-35 (non-functional)","termid":"PBO:0051155"}


id: PBO:0030742
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_cell_morphology_during_nitrogen_starvation","termid":"PBO:0030742"}


id: FYPO:0003531
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which peroxisome size is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal subcellular component during vegetative growth","termid":"FYPO:0001313"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal peroxisome size","synonyms":[{"name":"normal peroxisome size during mitotic cell cycle","type":"related"},{"name":"normal peroxisome size during vegetative growth","type":"exact"}],"termid":"FYPO:0003531"}


id: GO:0140438
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The covalent attachment of a stearoyl group to an amino acid in a protein.","definition_xrefs":["PMID:26214738"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein lipidation","termid":"GO:0006497"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0042158"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0042158","GO:0008150"],"is_obsolete":false,"name":"protein stearoylation","termid":"GO:0140438"}


id: PBO:0074702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 71B","termid":"PBO:0074702"}


id: GO:0151001
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A dense cluster of elongated, thick microvilli on the apical surface of tuft cells in epithelial tissues, such as the intestine and respiratory tract. The apical tuft extends further into the lumen than typical microvilli, featuring larger, more compact projections with unique actin cores that penetrate deep into the cytoplasm, often reaching the perinuclear region. This distinctive structure, rich in microfilaments and microtubules, supports the chemosensory functions of the cell.","definition_xrefs":["PMID:15817800","PMID:35237268"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cluster of actin-based cell projections","termid":"GO:0098862"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"tuft","termid":"GO:0151001"}


id: PBO:0084683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58","termid":"PBO:0084683"}


id: FYPO:0005141
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is decreased.","definition_xrefs":["PMID:15238514","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiotic recombination double-strand break repair","termid":"FYPO:0005139"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000298","FYPO:0000002","FYPO:0005447","FYPO:0000293","FYPO:0001985"],"is_obsolete":false,"name":"decreased meiotic recombination double-strand break repair","synonyms":[{"name":"decreased DSB repair involved in reciprocal meiotic recombination","type":"exact"},{"name":"decreased double-strand break repair during meiotic recombination","type":"exact"},{"name":"decreased double-strand break repair involved in reciprocal meiotic recombination","type":"exact"},{"name":"reduced meiotic recombination double-strand break repair","type":"exact"}],"termid":"FYPO:0005141"}


id: SO:0000969
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000969 rolling_circle (obsolete SO:0000969)","secondary_identifiers":["http://en.wikipedia.org/wiki/Rolling_circle"],"synonyms":[{"name":"rolling circle","type":"exact"}],"termid":"SO:0000969"}


id: PBO:0081409
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 257","termid":"PBO:0081409"}


id: MOD:01816
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-tryptophan residue to a 2'-hydroxy-L-tryptophan.","definition_xrefs":["RESID:AA0542","PubMed:11714714"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monohydroxylated tryptophan","termid":"MOD:01622"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2'-hydroxy-L-tryptophan","synonyms":[{"name":"(2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid","type":"exact"},{"name":"2'-hydroxy-L-tryptophan","type":"exact"},{"name":"2-azanyl-3-(2-hydroxy-1H-indol-3-yl)propanoic acid","type":"exact"},{"name":"2-hydroxy-L-tryptophan","type":"exact"},{"name":"2-hydroxy-tryptophan","type":"exact"}],"termid":"MOD:01816"}


id: PBO:0000664
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EF hand family protein, unknown role","termid":"PBO:0000664"}


id: PBO:0011112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intergenic RNA Omt3","termid":"PBO:0011112"}


id: MONDO:0020450
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital anomaly of the inferior vena cava","termid":"MONDO:0019830"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"azygos continuation of the inferior vena cava","secondary_identifiers":["UMLS:C1859772","Orphanet:99121","MEDGEN:347231","GARD:19662"],"synonyms":[{"name":"azygos continuation of the IVC","type":"exact"},{"name":"azygos continuation of the inferior caval vein","type":"exact"}],"termid":"MONDO:0020450","xrefs":{"Monarch":{"xref_id":"0020450"}}}


id: MONDO:0012756
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A chromosomal anomaly characterized by developmental and language delays, mild intellectual disability, social impairments (autism spectrum disorders), mild variable dysmorphism and predisposition to obesity.","definition_xrefs":["Orphanet:261197"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of the short arm of chromosome 16","termid":"MONDO:0016894"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proximal 16p11.2 microdeletion syndrome","secondary_identifiers":["SCTID:718227006","UMLS:C3150154","SCTID:699307007","DOID:0070515","MEDGEN:461504","OMIM:611913","ICD9:758.39","MESH:C579850","NCIT:C120408","GARD:10740"],"synonyms":[{"name":"16p11.2 deletion syndrome","type":"related"},{"name":"Del(16)(p11.2)","type":"related"},{"name":"autism susceptibility 14A","type":"exact"},{"name":"autism, susceptibility to, 14A","type":"related"},{"name":"chromosome 16p11.2 deletion syndrome","type":"related"},{"name":"chromosome 16p11.2 deletion syndrome, 593-KB","type":"related"},{"name":"chromosome 16p11.2 deletion syndrome, 593kb","type":"exact"},{"name":"microdeletion 16p11.2","type":"related"},{"name":"monosomy 16p11.2","type":"related"},{"name":"proximal del(16)(p11.2)","type":"exact"},{"name":"proximal monosomy 16p11.2","type":"exact"}],"termid":"MONDO:0012756","xrefs":{"Monarch":{"xref_id":"0012756"}}}


id: PBO:0056421
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MARCKS like 1 pseudogene 2","termid":"PBO:0056421"}


id: PBO:0061260
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"notch 2 N-terminal like C","termid":"PBO:0061260"}


id: GO:1904505
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.","definition_xrefs":["PMID:22579284","GOC:BHF","GO_REF:0000058","GOC:BHF_telomere","GOC:nc","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of telomere maintenance","termid":"GO:0032204"},{"relation_name":"is_a","term_name":"regulation of cellular response to stress","termid":"GO:0080135"},{"relation_name":"regulates","term_name":"telomere maintenance in response to DNA damage","termid":"GO:0043247"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0032200"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006259","GO:0032200"],"is_obsolete":false,"name":"regulation of telomere maintenance in response to DNA damage","synonyms":[{"name":"regulation of DNA damage response, telomere maintenance","type":"exact"}],"termid":"GO:1904505"}


id: GO:0032631
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine production","termid":"GO:0001816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"interleukin-27 production","secondary_identifiers":["GO:0045527","GO:0072625"],"synonyms":[{"name":"IL-27 production","type":"exact"},{"name":"interleukin-27 biosynthetic process","type":"narrow"},{"name":"interleukin-27 formation","type":"narrow"},{"name":"interleukin-27 secretion","type":"narrow"},{"name":"interleukin-27 synthesis","type":"narrow"}],"termid":"GO:0032631"}


id: PBO:0064686
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase A pseudogene 22","termid":"PBO:0064686"}


id: PBO:0084084
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA1 has a paralog, GEA2, that arose from the whole genome duplication","termid":"PBO:0084084"}


id: PBO:0074277
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLIRP. pseudogene 1","termid":"PBO:0074277"}


id: GO:1900667
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ketone biosynthetic process","termid":"GO:0010566"},{"relation_name":"is_a","term_name":"regulation of secondary metabolite biosynthetic process","termid":"GO:1900376"},{"relation_name":"regulates","term_name":"endocrocin biosynthetic process","termid":"GO:1900602"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0019748"],"is_obsolete":false,"name":"regulation of endocrocin biosynthetic process","synonyms":[{"name":"regulation of endocrocin anabolism","type":"exact"},{"name":"regulation of endocrocin biosynthesis","type":"exact"},{"name":"regulation of endocrocin formation","type":"exact"},{"name":"regulation of endocrocin synthesis","type":"exact"}],"termid":"GO:1900667"}


id: GO:1903504
data:
  {"annotated_genes":["SJAG_01679","SJAG_00883","SJAG_04259","SJAG_01837","SJAG_02336","SJAG_01297","SJAG_02169","SJAG_03681","SJAG_03126","SJAG_02451","SJAG_03353"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[115034,89932,103069,111101,107405,113401,112911,98782,106393],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902426"},{"annotations":[93399],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140499"},{"annotations":[115809],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090267"},{"annotations":[93400],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090266"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.","definition_xrefs":["PMID:23442800","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mitotic cell cycle","termid":"GO:0007346"},{"relation_name":"is_a","term_name":"regulation of spindle checkpoint","termid":"GO:0090231"},{"relation_name":"regulates","term_name":"mitotic spindle checkpoint signaling","termid":"GO:0071174"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00883":null,"SJAG_01297":null,"SJAG_01679":null,"SJAG_01837":null,"SJAG_02169":null,"SJAG_02336":null,"SJAG_02451":null,"SJAG_03126":null,"SJAG_03353":null,"SJAG_03681":null,"SJAG_04259":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0023052"],"is_obsolete":false,"name":"regulation of mitotic spindle checkpoint","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of mitotic cell cycle spindle checkpoint","type":"exact"}],"termid":"GO:1903504","terms_by_termid":{"GO:0090266":null,"GO:0090267":null,"GO:0140499":null,"GO:1902426":null}}


id: PBO:0018224
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit Med1","termid":"PBO:0018224"}


id: PBO:0059471
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MSL complex subunit 1","termid":"PBO:0059471"}


id: GO:0020018
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket).","definition_xrefs":["GOC:mb","GOC:cilia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ciliary membrane","termid":"GO:0060170"},{"relation_name":"part_of","term_name":"ciliary pocket","termid":"GO:0020016"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"ciliary pocket membrane","synonyms":[{"name":"cilial pocket membrane","type":"exact"},{"name":"cilium pocket membrane","type":"exact"},{"name":"flagellar pocket membrane","type":"exact"}],"termid":"GO:0020018"}


id: GO:0070273
data:
  {"annotated_genes":["SJAG_01769","SJAG_05179","SJAG_00663","SJAG_01516","SJAG_01945","SJAG_04077"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[93707,97917,98486,99308,101610,111635],"is_not":false,"summary":null,"term":"GO:0070273"}]},"cv_name":"molecular_function","definition":"Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.","definition_xrefs":["GOC:bf","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylinositol phosphate binding","termid":"GO:1901981"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00663":null,"SJAG_01516":null,"SJAG_01769":null,"SJAG_01945":null,"SJAG_04077":null,"SJAG_05179":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008289"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0008289","GO:0005488"],"is_obsolete":false,"name":"phosphatidylinositol-4-phosphate binding","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0070273","terms_by_termid":{"GO:0070273":null}}


id: PATO:0001426
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of purple and brown hue.","definition_xrefs":["Wikipedia:http://en.wikipedia.org/wiki/Maroon"],"direct_ancestors":[{"relation_name":"is_a","term_name":"color","termid":"PATO:0000014"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"maroon","termid":"PATO:0001426"}


id: FYPO:0007588
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to late endosomes does not occur.","definition_xrefs":["PMID:19624755","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to endosome","termid":"FYPO:0007587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"abolished protein localization to late endosome","synonyms":[{"name":"abolished protein localisation to late endosome","type":"exact"},{"name":"abolished protein localization to PVE","type":"exact"},{"name":"abolished protein localization to late endosome during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to late endosome during vegetative growth","type":"exact"},{"name":"abolished protein localization to prevacuolar compartment","type":"exact"},{"name":"abolished protein localization to prevacuolar endosome","type":"exact"},{"name":"protein localization to late endosome abolished","type":"exact"}],"termid":"FYPO:0007588"}


id: PBO:0034115
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_habitat","termid":"PBO:0034115"}


id: GO:0007638
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Behavior that is dependent upon the sensation of a mechanical stimulus.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavior","termid":"GO:0007610"},{"relation_name":"part_of","term_name":"response to mechanical stimulus","termid":"GO:0009612"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mechanosensory behavior","synonyms":[{"name":"behavioral response to mechanical stimulus","type":"exact"},{"name":"behavioural response to mechanical stimulus","type":"exact"},{"name":"mechanosensory behaviour","type":"exact"}],"termid":"GO:0007638"}


id: GO:0120034
data:
  {"annotated_genes":["SJAG_00514","SJAG_03453","SJAG_01794","SJAG_02379","SJAG_04509"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92674,89074,87107,110508,90054],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902917"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell projection organization","termid":"GO:0031346"},{"relation_name":"is_a","term_name":"positive regulation of cellular component biogenesis","termid":"GO:0044089"},{"relation_name":"is_a","term_name":"regulation of plasma membrane bounded cell projection assembly","termid":"GO:0120032"},{"relation_name":"positively_regulates","term_name":"plasma membrane bounded cell projection assembly","termid":"GO:0120031"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00514":null,"SJAG_01794":null,"SJAG_02379":null,"SJAG_03453":null,"SJAG_04509":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"positive regulation of plasma membrane bounded cell projection assembly","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0120034","terms_by_termid":{"GO:1902917":null}}


id: GO:0090513
data:
  {"annotated_genes":["SJAG_03256"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[103012],"is_not":false,"summary":null,"term":"GO:0090513"}]},"cv_name":"biological_process","definition":"The directed movement of L-histidine into the vacuole across the vacuolar membrane.","definition_xrefs":["GOC:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"basic amino acid transmembrane import into vacuole","termid":"GO:0034490"},{"relation_name":"is_a","term_name":"L-histidine transmembrane transport","termid":"GO:0089709"},{"relation_name":"is_a","term_name":"L-histidine transport","termid":"GO:1902024"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03256":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0055085","GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"L-histidine transmembrane import into vacuole","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0090457"],"synonyms":[{"name":"histidine transmembrane import into vacuole","type":"broad"},{"name":"vacuolar histidine import","type":"broad"}],"termid":"GO:0090513","terms_by_termid":{"GO:0090513":null}}


id: PBO:0080235
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vimentin type intermediate filament associated coiled-coil protein","termid":"PBO:0080235"}


id: PBO:0074007
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 25 member 5 pseudogene 8","termid":"PBO:0074007"}


id: FYPO:0002446
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to hydrogen peroxide.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein phosphorylation during cellular response to oxidative stress","termid":"FYPO:0007620"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002274","FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0002494"],"is_obsolete":false,"name":"decreased protein phosphorylation during cellular response to hydrogen peroxide","synonyms":[{"name":"decreased protein phosphorylation during cellular response to H2O2","type":"exact"},{"name":"decreased protein phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle","type":"related"},{"name":"decreased protein phosphorylation during cellular response to hydrogen peroxide during vegetative growth","type":"exact"},{"name":"reduced protein phosphorylation during cellular response to H2O2","type":"exact"},{"name":"reduced protein phosphorylation during cellular response to hydrogen peroxide","type":"exact"}],"termid":"FYPO:0002446"}


id: PBO:0046833
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fatty acid binding protein 5 pseudogene 6","termid":"PBO:0046833"}


id: PBO:0030451
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-growth_auxotrophic_for_lysine_and_methionine","termid":"PBO:0030451"}


id: PBO:0113167
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Integral ER membrane protein with type-III transmembrane domains; promotes ER membrane expansion by inhibiting the Nem1-Spo7 phosphatase complex, resulting in reduced dephosphorylation and activation of Pah1p; maintains homeostasis during ER stress; required for post-translational SRP-independent protein translocation into the ER; necessary for efficient targeting of the Trm1p to the inner nuclear membrane; mutations cause defects in cortical ER morphology; member of the SERINC superfamily","termid":"PBO:0113167"}


id: FYPO:0003853
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to fluconazole. Cells stop growing (and may die) at a concentration of fluconazole that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002683","FYPO:0001985","FYPO:0000003","FYPO:0000139"],"is_obsolete":false,"name":"sensitive to fluconazole","synonyms":[{"name":"hypersensitive to fluconazole","type":"exact"},{"name":"sensitive to fluconazole during mitotic cell cycle","type":"related"},{"name":"sensitive to fluconazole during vegetative growth","type":"exact"}],"termid":"FYPO:0003853"}


id: GO:0006232
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine ribonucleoside diphosphate biosynthetic process","termid":"GO:0009194"},{"relation_name":"is_a","term_name":"pyrimidine ribonucleotide biosynthetic process","termid":"GO:0009220"},{"relation_name":"is_a","term_name":"TDP metabolic process","termid":"GO:0046043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0055086","GO:0008150"],"is_obsolete":false,"name":"TDP biosynthetic process","synonyms":[{"name":"TDP anabolism","type":"exact"},{"name":"TDP biosynthesis","type":"exact"},{"name":"TDP formation","type":"exact"},{"name":"TDP synthesis","type":"exact"}],"termid":"GO:0006232"}


id: MONDO:0002183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder involving the attachment of a tendon or ligament to a bone","definition_xrefs":["Wikipedia:Enthesopathy"],"direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder","termid":"MONDO:0002081"},{"relation_name":"is_a","term_name":"connective tissue disorder","termid":"MONDO:0003900"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enthesopathy","secondary_identifiers":["ICD9:726.90","MESH:D012216","EFO:0009666","SCTID:23680005","MEDGEN:66909","ICD9:726.9","MESH:D000070676","DOID:204","UMLS:C0242490"],"synonyms":[{"name":"disease of enthesis","type":"exact"},{"name":"disease or disorder of enthesis","type":"exact"},{"name":"disorder of enthesis","type":"exact"},{"name":"enthesis disease","type":"exact"},{"name":"enthesis disease or disorder","type":"exact"}],"termid":"MONDO:0002183","xrefs":{"Monarch":{"xref_id":"0002183"}}}


id: MONDO:0010199
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"White forelock with malformations is a multiple congenital anomalies syndrome characterized by poliosis, distinct facial features (epicanthal folds, hypertelorism, posterior rotation of ears, prominent philtrum, high-arched palate) and congenital anomalies/malformations of the eye (blue sclera), cardiopulmonary (atrial septal defect, prominent thoracic and abdominal veins), and skeletal (clinodactyly, syndactyly of the fingers and 2nd and 3rd toes) systems. There have been no further descriptions in the literature since 1980.","definition_xrefs":["Orphanet:2475"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"white forelock with malformations","secondary_identifiers":["SCTID:763619009","MESH:C536700","GARD:10081","OMIM:277740","MEDGEN:376362","UMLS:C1848463"],"synonyms":[{"name":"white forelock with malformations","type":"exact"}],"termid":"MONDO:0010199","xrefs":{"Monarch":{"xref_id":"0010199"}}}


id: GO:0072227
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"macula densa development","termid":"GO:0072024"},{"relation_name":"is_a","term_name":"metanephric nephron epithelium development","termid":"GO:0072243"},{"relation_name":"part_of","term_name":"metanephric juxtaglomerular apparatus development","termid":"GO:0072206"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric macula densa development","termid":"GO:0072227"}


id: PR:O74340
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DDB1- and CUL4-associated factor 13 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03079","PRO:DNx","PANTHER:PTHR22851:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein sof1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1A4.07c","secondary_identifiers":["UniProtKB:O74340"],"synonyms":[{"name":"Spom972h-DCAF13","type":"exact"},{"name":"U3 small nucleolar RNA-associated protein sof1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"U3 snoRNA-associated protein sof1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74340"}


id: PBO:0113361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein serine/threonine kinase; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress","termid":"PBO:0113361"}


id: GO:0061882
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.","definition_xrefs":["PMID:24302729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of intracellular transport","termid":"GO:0032387"},{"relation_name":"is_a","term_name":"regulation of anterograde axonal transport of mitochondrion","termid":"GO:0061880"},{"relation_name":"negatively_regulates","term_name":"anterograde axonal transport of mitochondrion","termid":"GO:0098957"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of anterograde axonal transport of mitochondrion","synonyms":[{"name":"negative regulation of anterograde axon transport of mitochondria","type":"exact"}],"termid":"GO:0061882"}


id: MONDO:0002566
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete complex regional pain syndrome (obsolete MONDO:0002566)","termid":"MONDO:0002566","xrefs":{"Monarch":{"xref_id":"0002566"}}}


id: PBO:0046200
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin A3 family member D, pseudogene","termid":"PBO:0046200"}


id: MONDO:0009006
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Complement component 2 deficiency (C2D) is a genetic condition that affects the immune system. Signs and symptoms include recurrent bacterial infections and risk for a variety of autoimmune conditions. Infections can be very serious and are common in early life. They become less frequent during the teen and adult years. The most frequent autoimmune conditions associated with C2D are lupus (10-20%) and vasculitis. C2D is caused by mutations in the C2 gene and is inherited in an autosomal recessive fashion.","direct_ancestors":[{"relation_name":"is_a","term_name":"classic complement early component deficiency","termid":"MONDO:0000015"},{"relation_name":"is_a","term_name":"immunodeficiency due to a classical component pathway complement deficiency","termid":"MONDO:0015699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"complement component 2 deficiency","secondary_identifiers":["OMIM:217000","NCIT:C119992","NANDO:2200781","UMLS:C3150275","GARD:1452","MEDGEN:461625","DOID:0060295"],"synonyms":[{"name":"C2 complement deficiency","type":"exact"},{"name":"C2 deficiency","type":"related"},{"name":"C2D","type":"related"},{"name":"complement component 2 deficiency","type":"exact"},{"name":"complement deficiency caused by mutation in C2","type":"exact"}],"termid":"MONDO:0009006","xrefs":{"Monarch":{"xref_id":"0009006"}}}


id: PBO:0108980
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sperm associated microtubule inner protein 4","termid":"PBO:0108980"}


id: PBO:0070144
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 58 pseudogene","termid":"PBO:0070144"}


id: MOD:01983
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts a glycine residue to N,N-dimethyllglycine.","definition_xrefs":["RESID:AA0620","PubMed:23818633","ChEBI:17724","PubMed:23978223"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methylated glycine","termid":"MOD:00714"},{"relation_name":"is_a","term_name":"alpha-amino dimethylated residue","termid":"MOD:01686"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"N,N-dimethylglycine","synonyms":[{"name":"(dimethylamino)ethanoic acid","type":"exact"},{"name":"1-carboxy-N,N-dimethylaminomethane","type":"exact"},{"name":"2-(dimethylamino)acetic acid","type":"exact"},{"name":"MOD_RES N,N-dimethylglycine","type":"exact"},{"name":"vitamin B16","type":"exact"}],"termid":"MOD:01983"}


id: GO:0043417
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of skeletal muscle tissue regeneration","termid":"GO:0043416"},{"relation_name":"is_a","term_name":"negative regulation of developmental growth","termid":"GO:0048640"},{"relation_name":"is_a","term_name":"negative regulation of wound healing","termid":"GO:0061045"},{"relation_name":"negatively_regulates","term_name":"skeletal muscle tissue regeneration","termid":"GO:0043403"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of skeletal muscle tissue regeneration","synonyms":[{"name":"down regulation of skeletal muscle regeneration","type":"exact"},{"name":"down-regulation of skeletal muscle regeneration","type":"exact"},{"name":"downregulation of skeletal muscle regeneration","type":"exact"},{"name":"inhibition of skeletal muscle regeneration","type":"narrow"}],"termid":"GO:0043417"}


id: PR:Q9P6L9
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A dentin sialophosphoprotein that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01307","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C688.07c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC688.07c","secondary_identifiers":["UniProtKB:Q9P6L9"],"synonyms":[{"name":"Spom972h-DSPP","type":"exact"}],"termid":"PR:Q9P6L9"}


id: GO:0035199
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The specific avoidance actions or reactions of an organism in response to the perception of salt.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"feeding behavior","termid":"GO:0007631"},{"relation_name":"part_of","term_name":"response to chemical","termid":"GO:0042221"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"salt aversion","synonyms":[{"name":"behavioral response to salt","type":"broad"}],"termid":"GO:0035199"}


id: MONDO:0700021
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chromosomal disorder in which chromosome 14 is affected.","definition_xrefs":["MONDO:patterns/chromosome_type"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal anomaly","termid":"MONDO:0020049"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 14 disorder","termid":"MONDO:0700021","xrefs":{"Monarch":{"xref_id":"0700021"}}}


id: FYPO:0003825
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has two nuclei but no septum, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell cycle arrest at mitotic G2/M phase transition","termid":"FYPO:0000400"},{"relation_name":"is_a","term_name":"inviable binucleate aseptate cell with mitotic cell cycle arrest before cell separation","termid":"FYPO:0005689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0000032","FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0000631","FYPO:0000004","FYPO:0001985"],"is_obsolete":false,"name":"inviable binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation","synonyms":[{"name":"inviable binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation during vegetative growth","type":"exact"},{"name":"inviable binucleate aseptate cell with cell cycle arrest in mitotic G2 phase before cell separation","type":"related"},{"name":"inviable binucleate aseptate cell with mitotic G2/M phase transition arrest before cell separation","type":"exact"},{"name":"inviable binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cytokinesis","type":"exact"},{"name":"inviable binucleate aseptate cell with mitotic cell cycle arrest at G2/M phase transition before cell separation","type":"exact"},{"name":"inviable binucleate cell with mitotic cell cycle arrest at G2/M before division septum assembly","type":"exact"},{"name":"inviable cell with mitotic G2/M arrest after failed cytokinesis","type":"related"},{"name":"inviable cell with nuclear division arrest at G2/M without septation (normal cell length)","type":"exact"},{"name":"lethal; binucleate aseptate cell with mitotic cell cycle arrest at G2/M before cell separation","type":"exact"},{"name":"mitotic cell cycle arrest at G2/M before cell separation with inviable binucleate aseptate cell","type":"exact"}],"termid":"FYPO:0003825"}


id: MONDO:0018213
data:
  {"annotated_genes":["SJAG_04178","SJAG_02119","SJAG_02305"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85158],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013584"},{"annotations":[86169],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008086"},{"annotations":[86262],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013337"}]},"cv_name":"mondo","definition":"Hereditary sensory neuropathy type I (HSN I) is a slowly progressive neurological disorder characterized by prominent predominantly distal sensory loss, autonomic disturbances, autosomal dominant inheritance, and juvenile or adulthood disease onset.","definition_xrefs":["Orphanet:36386"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary sensory and autonomic neuropathy","termid":"MONDO:0015364"},{"relation_name":"is_a","term_name":"disorder of phospholipids, sphingolipids and fatty acids biosynthesis","termid":"MONDO:0018117"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02119":null,"SJAG_02305":null,"SJAG_04178":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005244","MONDO:0002525","MONDO:0005066"],"is_obsolete":false,"name":"hereditary sensory and autonomic neuropathy type 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0020071","DOID:0070162","GARD:6635","SCTID:397734008","MEDGEN:5645","icd11.foundation:1989773046","NORD:1237","PMID:18348718"],"synonyms":[{"name":"HSAN 1","type":"related"},{"name":"HSAN1","type":"exact"},{"name":"HSN1","type":"related"},{"name":"Hereditary Sensory Neuropathy Type I","type":"exact"},{"name":"hereditary sensory and autonomic neuropathy type I","type":"exact"},{"name":"hereditary sensory neuropathy type 1","type":"related"},{"name":"neuropathy hereditary sensory and autonomic type 1","type":"related"},{"name":"neuropathy hereditary sensory radicular, autosomal dominant","type":"related"}],"termid":"MONDO:0018213","terms_by_termid":{"MONDO:0008086":null,"MONDO:0013337":null,"MONDO:0013584":null},"xrefs":{"Monarch":{"xref_id":"0018213"}}}


id: PBO:0085462
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Predicted protein kinase; negatively regulates the hexosamine biosynthetic pathway (HBP), which converts fructose-6-phosphate into UDP-N-acetylglucosamine, a precursor of chitin biosynthesis, GPI-anchor formation and glycosylation; interacts genetically with GFA1, encoding the first enzyme in the HBP; involved in Gfa1p phosphorylation (S332, T334); contains a Pho85p-regulated SCF-CDC4 phosphodegron; unstable, cell cycle regulated protein, peaking at G1/S","termid":"PBO:0085462"}


id: GO:0071330
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to disaccharide stimulus","termid":"GO:0071324"},{"relation_name":"is_a","term_name":"response to trehalose-6-phosphate","termid":"GO:0080094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to trehalose-6-phosphate stimulus","termid":"GO:0071330"}


id: PBO:0063169
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAX interacting protein 1","termid":"PBO:0063169"}


id: MONDO:0017039
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"interstitial lung disease","termid":"MONDO:0015925"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"drug or radiation exposure-related interstitial lung disease","secondary_identifiers":["MEDGEN:1843006","UMLS:C5680746","Orphanet:264978","GARD:20942"],"termid":"MONDO:0017039","xrefs":{"Monarch":{"xref_id":"0017039"}}}


id: PBO:0053573
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 593","termid":"PBO:0053573"}


id: MONDO:0005122
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A bacterial infection induced by Pectobacterium carotovorum which is is a bacterium of the family Enterobacteriaceae. This bacterius is a ubiquitous plant pathogen with a wide host range (carrot, potato, tomato, leafy greens, squash and other cucurbits, onion, green peppers, African violets etc.), able to cause disease in almost any plant tissue it invades. It is a very economically important pathogen in terms of postharvest losses, and a common cause of decay in stored fruits and vegetables. Decay caused by E. carotovora is often simply referred to as \\\"bacterial soft rot\\\" (BSR) though this may also be caused by other bacteria. Most plants or plant parts can resist invasion by the bacteria, unless some type of wound is present. High humidity and temperatures around 30°C favor development of decay. Mutants can be produced which are less virulent. Virulence factors include: pectinases, cellulases, (which degrade plant cell walls), and also proteases, lipases, xylanases and nucleases (along with the normal virulence factors for pathogens – Fe acquisition, LPS integrity, multiple global regulatory systems).","definition_xrefs":["EFO:0000781"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial infectious disease","termid":"MONDO:0005113"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pectobacterium carotovorum infection","secondary_identifiers":["Wikipedia:Pectobacterium_carotovorum"],"synonyms":[{"name":"Pectobacterium caused disease or disorder","type":"exact"},{"name":"Pectobacterium disease or disorder","type":"exact"},{"name":"Pectobacterium infectious disease","type":"exact"}],"termid":"MONDO:0005122","xrefs":{"Monarch":{"xref_id":"0005122"}}}


id: MONDO:0800459
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Noxacusis/pain hyperacusis is characterized by individuals who experience otalgia or pain (e.g., dull ache, burning, sharp, stabbing pain and throbbing pain) in response to everyday sounds. This differs clinically from those whose primary symptom is the perception of everyday sounds as excessively loud (termed loudness hyperacusis).","definition_xrefs":["PMID:25104073","PMID:26553995"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hyperacusis","termid":"MONDO:0043303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"noxacusis","synonyms":[{"name":"auditory nociception","type":"exact"},{"name":"noise-induced pain","type":"exact"},{"name":"noxacusis","type":"exact"},{"name":"pain hyperacusis","type":"exact"}],"termid":"MONDO:0800459","xrefs":{"Monarch":{"xref_id":"0800459"}}}


id: GO:0005848
data:
  {"annotated_genes":["SJAG_02037","SJAG_04022","SJAG_03853","SJAG_03594","SJAG_01791","SJAG_01412"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[92659,97329,98286,98817,108968,110712],"is_not":false,"summary":null,"term":"GO:0005848"}]},"cv_name":"cellular_component","definition":"A protein complex required for mRNA cleavage but not for poly(A) addition.","definition_xrefs":["GOC:mah","PMID:10357856"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA cleavage factor complex","termid":"GO:0005849"}],"gene_count":6,"genes_by_uniquename":{"SJAG_01412":null,"SJAG_01791":null,"SJAG_02037":null,"SJAG_03594":null,"SJAG_03853":null,"SJAG_04022":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0032991","GO:0005634","GO:0005575"],"is_obsolete":false,"name":"mRNA cleavage stimulating factor complex","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"CstF complex","type":"narrow"},{"name":"cleavage stimulation factor activity","type":"related"}],"termid":"GO:0005848","terms_by_termid":{"GO:0005848":null}}


id: FYPO:0002419
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell population phenotype in which all vegetative cells arising from a population of germinated spores are inviable, and do not divide before dying.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable vegetative cell population after spore germination, without cell division (obsolete FYPO:0002419)","synonyms":[{"name":"inviable germinated spore population, without cell division","type":"exact"},{"name":"inviable population of undivided germinated spores","type":"exact"}],"termid":"FYPO:0002419"}


id: PBO:0061846
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Obg like ATPase 1","termid":"PBO:0061846"}


id: PBO:0074482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SET and MYND domain containing 1","termid":"PBO:0074482"}


id: GO:0048475
data:
  {"annotated_genes":["SJAG_01508","SJAG_00104","SJAG_05345","SJAG_02482","SJAG_02234","SJAG_04474","SJAG_00906","SJAG_03726","SJAG_04569","SJAG_00379","SJAG_04002","SJAG_00284","SJAG_00800","SJAG_00192","SJAG_02805","SJAG_00072","SJAG_04391","SJAG_02539","SJAG_01167","SJAG_04609","SJAG_04070","SJAG_03907","SJAG_02453","SJAG_02349","SJAG_03558","SJAG_04565","SJAG_04517","SJAG_02282","SJAG_01809","SJAG_05344","SJAG_03153","SJAG_00108","SJAG_04644","SJAG_04931","SJAG_02177"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[100310,111914,112129,118004],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030121"},{"annotations":[107482,95460,110792,110733],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030122"},{"annotations":[88112,110634,93383,95324],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030123"},{"annotations":[110637],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030131"},{"annotations":[94087,112038],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030130"},{"annotations":[94088],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0071439"},{"annotations":[117615,114011],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030125"},{"annotations":[103293,112880,97650,97739,102442,115506,92422,106281,116531],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030126"},{"annotations":[107877,92554,70770,115725,94706,111845,74362,105723,109353,111115],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030127"}]},"cv_name":"cellular_component","definition":"A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane","termid":"GO:0016020"}],"gene_count":35,"genes_by_uniquename":{"SJAG_00072":null,"SJAG_00104":null,"SJAG_00108":null,"SJAG_00192":null,"SJAG_00284":null,"SJAG_00379":null,"SJAG_00800":null,"SJAG_00906":null,"SJAG_01167":null,"SJAG_01508":null,"SJAG_01809":null,"SJAG_02177":null,"SJAG_02234":null,"SJAG_02282":null,"SJAG_02349":null,"SJAG_02453":null,"SJAG_02482":null,"SJAG_02539":null,"SJAG_02805":null,"SJAG_03153":null,"SJAG_03558":null,"SJAG_03726":null,"SJAG_03907":null,"SJAG_04002":null,"SJAG_04070":null,"SJAG_04391":null,"SJAG_04474":null,"SJAG_04517":null,"SJAG_04565":null,"SJAG_04569":null,"SJAG_04609":null,"SJAG_04644":null,"SJAG_04931":null,"SJAG_05344":null,"SJAG_05345":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"coated membrane","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0048475","terms_by_termid":{"GO:0030121":null,"GO:0030122":null,"GO:0030123":null,"GO:0030125":null,"GO:0030126":null,"GO:0030127":null,"GO:0030130":null,"GO:0030131":null,"GO:0071439":null}}


id: PBO:0039086
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP/GTP binding carboxypeptidase 1","termid":"PBO:0039086"}


id: GO:0016084
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.","definition_xrefs":["PMID:12204246","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hormone activity","termid":"GO:0005179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140677"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0098772","GO:0003674","GO:0140677","GO:0005515"],"is_obsolete":false,"name":"myostimulatory hormone activity","termid":"GO:0016084"}


id: MONDO:0035605
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"precursor lymphoblastic lymphoma/leukemia","termid":"MONDO:0003538"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality","secondary_identifiers":["UMLS:C2698313","MEDGEN:396322","ICD10CM:C91.0","NCIT:C80328","Orphanet:585877","GARD:22341"],"termid":"MONDO:0035605","xrefs":{"Monarch":{"xref_id":"0035605"}}}


id: PBO:0069347
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 607, pseudogene","termid":"PBO:0069347"}


id: PBO:0016982
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U2 Auxiliary Factor","termid":"PBO:0016982"}


id: GO:1900289
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.","definition_xrefs":["GOC:TermGenie","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of catabolic process","termid":"GO:0009895"},{"relation_name":"is_a","term_name":"regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process","termid":"GO:1900288"},{"relation_name":"negatively_regulates","term_name":"coenzyme F420-dependent bicyclic nitroimidazole catabolic process","termid":"GO:0052799"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process","synonyms":[{"name":"down regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process","type":"exact"},{"name":"down regulation of coenzyme F420-dependent nitroimidazole breakdown","type":"exact"},{"name":"down regulation of coenzyme F420-dependent nitroimidazole catabolism","type":"exact"},{"name":"down regulation of coenzyme F420-dependent nitroimidazole reduction","type":"exact"},{"name":"down regulation of coenzyme F420-dependent nitroreductase activity","type":"related"},{"name":"down-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process","type":"exact"},{"name":"down-regulation of coenzyme F420-dependent nitroimidazole breakdown","type":"exact"},{"name":"down-regulation of coenzyme F420-dependent nitroimidazole catabolism","type":"exact"},{"name":"down-regulation of coenzyme F420-dependent nitroimidazole reduction","type":"exact"},{"name":"down-regulation of coenzyme F420-dependent nitroreductase activity","type":"related"},{"name":"downregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process","type":"exact"},{"name":"downregulation of coenzyme F420-dependent nitroimidazole breakdown","type":"exact"},{"name":"downregulation of coenzyme F420-dependent nitroimidazole catabolism","type":"exact"},{"name":"downregulation of coenzyme F420-dependent nitroimidazole reduction","type":"exact"},{"name":"downregulation of coenzyme F420-dependent nitroreductase activity","type":"related"},{"name":"inhibition of coenzyme F420-dependent bicyclic nitroimidazole catabolic process","type":"narrow"},{"name":"inhibition of coenzyme F420-dependent nitroimidazole breakdown","type":"narrow"},{"name":"inhibition of coenzyme F420-dependent nitroimidazole catabolism","type":"narrow"},{"name":"inhibition of coenzyme F420-dependent nitroimidazole reduction","type":"narrow"},{"name":"inhibition of coenzyme F420-dependent nitroreductase activity","type":"related"},{"name":"negative regulation of coenzyme F420-dependent nitroimidazole breakdown","type":"exact"},{"name":"negative regulation of coenzyme F420-dependent nitroimidazole catabolism","type":"exact"},{"name":"negative regulation of coenzyme F420-dependent nitroimidazole reduction","type":"exact"},{"name":"negative regulation of coenzyme F420-dependent nitroreductase activity","type":"related"}],"termid":"GO:1900289"}


id: PBO:0030998
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_degradation_during_vegetative_growth","termid":"PBO:0030998"}


id: PBO:0028161
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_ATP_binding","termid":"PBO:0028161"}


id: GO:0110098
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.","definition_xrefs":["PMID:24085037","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of calcium import into the mitochondrion","termid":"GO:0110097"},{"relation_name":"is_a","term_name":"positive regulation of calcium ion transmembrane transport","termid":"GO:1904427"},{"relation_name":"positively_regulates","term_name":"calcium import into the mitochondrion","termid":"GO:0036444"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"positive regulation of calcium import into the mitochondrion","termid":"GO:0110098"}


id: GO:0030195
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of blood coagulation","termid":"GO:0030193"},{"relation_name":"is_a","term_name":"negative regulation of coagulation","termid":"GO:0050819"},{"relation_name":"is_a","term_name":"negative regulation of wound healing","termid":"GO:0061045"},{"relation_name":"is_a","term_name":"negative regulation of hemostasis","termid":"GO:1900047"},{"relation_name":"negatively_regulates","term_name":"blood coagulation","termid":"GO:0007596"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of blood coagulation","synonyms":[{"name":"down regulation of blood coagulation","type":"exact"},{"name":"down-regulation of blood coagulation","type":"exact"},{"name":"downregulation of blood coagulation","type":"exact"},{"name":"inhibition of blood coagulation","type":"narrow"}],"termid":"GO:0030195"}


id: PBO:0032746
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol polyphosphate phosphatase Fig4 (predicted)","termid":"PBO:0032746"}


id: GO:0015341
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force.","definition_xrefs":["TC:2.A.4.1.4","GOC:mtg_transport","ISBN:0815340729","TC:2.A.4.2.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secondary active transmembrane transporter activity","termid":"GO:0015291"},{"relation_name":"is_a","term_name":"active monoatomic ion transmembrane transporter activity","termid":"GO:0022853"},{"relation_name":"is_a","term_name":"zinc efflux transmembrane transporter activity","termid":"GO:0022883"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"zinc efflux active transmembrane transporter activity","synonyms":[{"name":"zinc efflux permease activity","type":"broad"}],"termid":"GO:0015341"}


id: MONDO:0011123
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing type 1 diabetes mellitus that has material basis in mutation of the locus at chromosome 6q21.","definition_xrefs":["DOID:0110753","PMID:8981961","MONDO:patterns/inherited_susceptibility"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"type 1 diabetes mellitus","termid":"MONDO:0005147"},{"relation_name":"is_a","term_name":"diabetes mellitus, insulin-dependent, X-linked, susceptibility to","termid":"MONDO:0010255"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"type 1 diabetes mellitus 15","secondary_identifiers":["MEDGEN:401019","MESH:C566645","OMIM:601666","UMLS:C1866519"],"synonyms":[{"name":"IDDM15","type":"exact"},{"name":"diabetes mellitus, insulin-dependent, 15","type":"related"},{"name":"insulin-dependent diabetes mellitus 15","type":"exact"}],"termid":"MONDO:0011123","xrefs":{"Monarch":{"xref_id":"0011123"}}}


id: SO:0000112
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An oligo to which new deoxyribonucleotides can be added by DNA polymerase.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ss_oligo","termid":"SO:0000441"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"primer","secondary_identifiers":["http://en.wikipedia.org/wiki/Primer_(molecular_biology)"],"synonyms":[{"name":"DNA primer","type":"exact"},{"name":"primer oligonucleotide","type":"exact"},{"name":"primer polynucleotide","type":"exact"},{"name":"primer sequence","type":"exact"}],"termid":"SO:0000112"}


id: PBO:0001501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNase P subunit (predicted)","termid":"PBO:0001501"}


id: MONDO:0100454
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any inherited retinal dystrophy in which the cause of the disease is a mutation in the GUCY2D gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited retinal dystrophy","termid":"MONDO:0019118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"GUCY2D retinopathy","synonyms":[{"name":"retinopathy caused by mutation in GUCY2D","type":"exact"}],"termid":"MONDO:0100454","xrefs":{"Monarch":{"xref_id":"0100454"}}}


id: PBO:0056557
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"minichromosome maintenance complex component 5","termid":"PBO:0056557"}


id: PBO:0066260
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RBMX like 3","termid":"PBO:0066260"}


id: PBO:0080583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 6","termid":"PBO:0080583"}


id: PBO:0049614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H3 histone pseudogene 17","termid":"PBO:0049614"}


id: PBO:0083231
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely within telomere TEL08L","termid":"PBO:0083231"}


id: FYPO:0006552
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to cytoplasm","termid":"FYPO:0006098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"increased protein localization to cytoplasm","synonyms":[{"name":"increased protein localisation to cytoplasm","type":"exact"},{"name":"increased protein localization to cytoplasm during mitotic cell cycle","type":"related"},{"name":"increased protein localization to cytoplasm during vegetative growth","type":"exact"}],"termid":"FYPO:0006552"}


id: PBO:0080564
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Williams-Beuren syndrome chromosome region 2","termid":"PBO:0080564"}


id: MONDO:0001219
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acute conjunctivitis","termid":"MONDO:0001214"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"serous conjunctivitis except viral","secondary_identifiers":["SCTID:9824006","MEDGEN:509805","UMLS:C0155142","ICD9:372.01","DOID:11197"],"synonyms":[{"name":"serous conjunctivitis, except viral","type":"exact"}],"termid":"MONDO:0001219","xrefs":{"Monarch":{"xref_id":"0001219"}}}


id: PBO:0029821
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_microcolony,_swollen_cells,_abnormal_cell_shape_(obsolete_FYPO:0002416)","termid":"PBO:0029821"}


id: MONDO:0021025
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cirrhosis, familial","termid":"MONDO:0007329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0019303"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004335","MONDO:0019303"],"is_obsolete":false,"name":"cirrhosis, familial, with antigenemia","secondary_identifiers":["OMIM:118900"],"synonyms":[{"name":"cirrhosis, familial","type":"related"}],"termid":"MONDO:0021025","xrefs":{"Monarch":{"xref_id":"0021025"}}}


id: PBO:0040534
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beta-1,3-galactosyltransferase 1","termid":"PBO:0040534"}


id: GO:0003360
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"brainstem development","termid":"GO:0003360"}


id: PBO:0039273
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ALG1 like 1, pseudogene","termid":"PBO:0039273"}


id: GO:0002563
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which immune receptor genes are diversified through alternate splicing.","definition_xrefs":["GOC:add","ISBN:0781735149","PMID:16166509"],"direct_ancestors":[{"relation_name":"is_a","term_name":"somatic diversification of immune receptors","termid":"GO:0002200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"somatic diversification of immune receptors via alternate splicing","termid":"GO:0002563"}


id: PBO:0049106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 161","termid":"PBO:0049106"}


id: PBO:0086583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin; null mutant sensitive to expression of top1-T722A allele","termid":"PBO:0086583"}


id: MONDO:0016449
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"dermis disorder","termid":"MONDO:0021154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"mid-dermal elastolysis","secondary_identifiers":["icd11.foundation:1379952112","UMLS:C4728147","MEDGEN:1672488","Orphanet:228299","GARD:20589"],"termid":"MONDO:0016449","xrefs":{"Monarch":{"xref_id":"0016449"}}}


id: PBO:0085057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-essential protein of unknown function; required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation; contains twin cysteine-x9-cysteine motifs; deletion affects mitochondrial morphology","termid":"PBO:0085057"}


id: PBO:0065134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein activator of interferon induced protein kinase EIF2AK2 pseudogene 1","termid":"PBO:0065134"}


id: FYPO:0000201
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone deacetylation is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone modification during vegetative growth","termid":"FYPO:0000330"},{"relation_name":"is_a","term_name":"abnormal protein deacetylation during vegetative growth","termid":"FYPO:0004485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0002494","FYPO:0002274","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"abnormal histone deacetylation during vegetative growth","synonyms":[{"name":"abnormal histone deacetylation during mitotic cell cycle","type":"related"}],"termid":"FYPO:0000201"}


id: PR:000027587
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A fungal histone H3.1, initiator methionine removed unphosphorylated form in Schizosaccharomyces pombe. Example: UniProtKB:P09988-1, 2-136.","definition_xrefs":["PomBase:MAH","PMID:11242054","PMID:20929775"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H3.1, initiator methionine removed form (Schizosaccharomyces pombe)","termid":"PR:000027574"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone H3.1, initiator methionine removed unphosphorylated form (Schizosaccharomyces pombe)","pombase_gene_id":"SPAC1834.04","synonyms":[{"name":"Spom-hht1/InitMet-/PhosRes-","type":"exact"}],"termid":"PR:000027587"}


id: PBO:0031336
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_benomyl","termid":"PBO:0031336"}


id: PBO:0061878
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oocyte secreted protein 1 pseudogene 2","termid":"PBO:0061878"}


id: GO:0099106
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"channel regulator activity","termid":"GO:0016247"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0098772","GO:0003674"],"is_obsolete":false,"name":"ion channel regulator activity","termid":"GO:0099106"}


id: GO:0090637
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane.","definition_xrefs":["PMID:20066089"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"desmosome","termid":"GO:0030057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"inner dense plaque of desmosome","termid":"GO:0090637"}


id: GO:0051498
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.","definition_xrefs":["MetaCyc:RXN-8528"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular lyase activity","termid":"GO:0016872"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016853","GO:0003674"],"is_obsolete":false,"name":"syn-copalyl diphosphate synthase activity","secondary_identifiers":["RHEA:25524","EC:5.5.1.14"],"synonyms":[{"name":"diterpene cyclase activity","type":"broad"}],"termid":"GO:0051498"}


id: GO:0060255
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