# terms

id: PR:Q9Y7P7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC191.03c gene.","definition_xrefs":["UniProtKB:Q9Y7P7","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C191.03c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC191.03c","synonyms":[{"name":"Spom972h-SPCC191.03c","type":"exact"}],"termid":"PR:Q9Y7P7"}


id: GO:1904928
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Any coreceptor activity that is involved in a canonical Wnt signaling pathway.","definition_xrefs":["PMID:24431302","GO_REF:0000061","GOC:PARL","GOC:TermGenie","GOC:bf"],"gene_count":0,"genotype_count":0,"name":"obsolete coreceptor activity involved in canonical Wnt signaling pathway (obsolete GO:1904928)","synonyms":[{"name":"Wnt co-receptor activity, canonical signaling","type":"exact"},{"name":"Wnt co-receptor, canonical pathway","type":"exact"},{"name":"coreceptor activity involved in Wnt receptor signaling pathway through beta-catenin","type":"exact"},{"name":"coreceptor activity involved in Wnt receptor signaling pathway via beta-catenin","type":"exact"},{"name":"coreceptor activity involved in Wnt receptor signalling pathway through beta-catenin","type":"exact"},{"name":"coreceptor activity involved in canonical Wnt receptor signaling pathway","type":"exact"},{"name":"coreceptor activity involved in canonical Wnt-activated signaling pathway","type":"exact"},{"name":"coreceptor activity involved in frizzled-1 receptor signaling pathway","type":"narrow"},{"name":"coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin","type":"related"},{"name":"coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin","type":"related"},{"name":"coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin","type":"related"},{"name":"coreceptor, insoluble ligand activity involved in canonical Wnt receptor signaling pathway","type":"related"},{"name":"coreceptor, insoluble ligand activity involved in canonical Wnt signaling pathway","type":"related"},{"name":"coreceptor, insoluble ligand activity involved in canonical Wnt-activated signaling pathway","type":"related"},{"name":"coreceptor, insoluble ligand activity involved in frizzled-1 receptor signaling pathway","type":"related"},{"name":"coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin","type":"related"},{"name":"coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin","type":"related"},{"name":"coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin","type":"related"},{"name":"coreceptor, soluble ligand activity involved in canonical Wnt receptor signaling pathway","type":"related"},{"name":"coreceptor, soluble ligand activity involved in canonical Wnt signaling pathway","type":"related"},{"name":"coreceptor, soluble ligand activity involved in canonical Wnt-activated signaling pathway","type":"related"},{"name":"coreceptor, soluble ligand activity involved in frizzled-1 receptor signaling pathway","type":"related"}],"termid":"GO:1904928"}


id: PBO:0040367
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase peripheral stalk-membrane subunit b pseudogene 4","termid":"PBO:0040367"}


id: PBO:0075640
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small proline rich protein 5","termid":"PBO:0075640"}


id: PBO:0078449
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor gamma variable 2","termid":"PBO:0078449"}


id: MONDO:0015872
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete giant adenofibroma of the breast (obsolete MONDO:0015872)","termid":"MONDO:0015872","xrefs":{"Monarch":{"xref_id":"0015872"}}}


id: MONDO:0019873
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"4p16.3 microduplication syndrome is a rare genetic syndrome that results from the partial duplication of the short arm of chromosome 4. It has a highly variable phenotype, principally characterized by psychomotor and language delay, seizures and dysmorphic features such as high forehead with frontal bossing, hypertelorism, prominent glabella, long narrow palpebral fissures, low set ears and short neck. Eye abnormalities (glaucoma, irregular iris pigmentation, hyperopia) have also been reported.","definition_xrefs":["Orphanet:96072"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of the short arm of chromosome 4","termid":"MONDO:0016941"},{"relation_name":"is_a","term_name":"overgrowth syndrome","termid":"MONDO:0019716"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4p16.3 microduplication syndrome","secondary_identifiers":["SCTID:726706008","GARD:19306","UMLS:C4512053","MEDGEN:1387521"],"synonyms":[{"name":"distal duplication 4p","type":"exact"},{"name":"distal trisomy 4p","type":"exact"},{"name":"telomeric duplication 4p","type":"exact"},{"name":"trisomy 4pter","type":"exact"}],"termid":"MONDO:0019873","xrefs":{"Monarch":{"xref_id":"0019873"}}}


id: SO:0001431
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene that is not transcribed under normal conditions and is not critical to normal cellular functioning.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"cryptic","termid":"SO:0000976"},{"relation_name":"is_a","term_name":"gene","termid":"SO:0000704"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cryptic_gene","synonyms":[{"name":"cryptic gene","type":"exact"}],"termid":"SO:0001431"}


id: PBO:0004243
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PPP3/PP2B/calcineurin subfamily","termid":"PBO:0004243"}


id: GO:0009834
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.","definition_xrefs":["GOC:mtg_sensu","GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plant-type cell wall biogenesis","termid":"GO:0009832"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0071554"},{"rel_name":"is_a","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0071554","GO:0044085"],"is_obsolete":false,"name":"plant-type secondary cell wall biogenesis","synonyms":[{"name":"cellulose and pectin-containing secondary cell wall biogenesis","type":"exact"},{"name":"secondary cell wall anabolism","type":"broad"},{"name":"secondary cell wall biogenesis","type":"exact"},{"name":"secondary cell wall biosynthetic process","type":"broad"},{"name":"secondary cell wall formation","type":"broad"},{"name":"secondary cell wall synthesis","type":"broad"}],"termid":"GO:0009834"}


id: GO:0002513
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Tolerance induction directed at self antigens.","definition_xrefs":["ISBN:0781735149","GO_REF:0000022","GOC:jal"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tolerance induction","termid":"GO:0002507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tolerance induction to self antigen","termid":"GO:0002513"}


id: PBO:0059972
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND3 pseudogene 17","termid":"PBO:0059972"}


id: GO:1902847
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of neuronal signal transduction.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","GOC:sjp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"regulates","term_name":"neuronal signal transduction","termid":"GO:0023041"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of neuronal signal transduction","termid":"GO:1902847"}


id: MONDO:0014969
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of pentose phosphate metabolism","termid":"MONDO:0019231"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0005066"],"is_obsolete":false,"name":"isolated sedoheptulokinase deficiency","secondary_identifiers":["SCTID:124309005","UMLS:C1291373","OMIM:617213","MEDGEN:713680","Orphanet:440713","GARD:18652","ICD9:277.6"],"synonyms":[{"name":"SHPKD","type":"exact"},{"name":"isolated SHPK deficiency","type":"exact"},{"name":"sedoheptulokinase deficiency","type":"exact"}],"termid":"MONDO:0014969","xrefs":{"Monarch":{"xref_id":"0014969"}}}


id: GO:0019687
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetate metabolic process","termid":"GO:0006083"},{"relation_name":"is_a","term_name":"pyruvate biosynthetic process","termid":"GO:0042866"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"pyruvate biosynthetic process from acetate","synonyms":[{"name":"pyruvate anabolism from acetate","type":"exact"},{"name":"pyruvate formation from acetate","type":"exact"},{"name":"pyruvate synthesis from acetate","type":"exact"}],"termid":"GO:0019687"}


id: GO:0050166
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (R)-pantoate + NAD+ = (R)-4-dehydropantoate + H+ + NADH.","definition_xrefs":["EC:1.1.1.106","RHEA:23000"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"pantoate 4-dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R02471","MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN"],"synonyms":[{"name":"(R)-pantoate:NAD+ 4-oxidoreductase activity","type":"related"},{"name":"D-pantoate:NAD+ 4-oxidoreductase activity","type":"related"},{"name":"panthothenase activity","type":"related"},{"name":"pantoate dehydrogenase activity","type":"related"}],"termid":"GO:0050166"}


id: GO:0051875
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle localization","termid":"GO:0051648"},{"relation_name":"part_of","term_name":"cellular pigmentation","termid":"GO:0033059"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"pigment granule localization","synonyms":[{"name":"pigment granule localisation","type":"exact"}],"termid":"GO:0051875"}


id: GO:0052711
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).","definition_xrefs":["KEGG_REACTION:R04878"],"gene_count":0,"genotype_count":0,"name":"obsolete ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (obsolete GO:0052711)","synonyms":[{"name":"N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism to ergothioneine","type":"exact"},{"name":"ergothioneine biosynthesis from hercynine","type":"exact"},{"name":"ergothioneine biosynthesis from histidine betaine","type":"exact"},{"name":"hercynine catabolism to ergothioneine","type":"exact"},{"name":"histidine betaine catabolism to ergothioneine","type":"exact"}],"termid":"GO:0052711"}


id: MONDO:0016063
data:
  {"annotated_genes":["SJAG_02426","SJAG_02539","SJAG_03131","SJAG_03153","SJAG_04206","SJAG_04394"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85050],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008021"},{"annotations":[84466,84467,84468],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014048"},{"annotations":[85026,85025],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014802"}]},"cv_name":"mondo","definition":"A genodermatosis characterized by the presence of multiple hamartomas in various tissues and an increased risk for malignancies of the breast, thyroid, endometrium, kidney and colorectum. When CS is accompanied by germline PTEN mutations, it belongs to the PTEN hamartoma tumor syndrome (PHTS) group.","definition_xrefs":["Orphanet:201"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"intestinal polyposis syndrome","termid":"MONDO:0015185"},{"relation_name":"excluded_subClassOf","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"},{"relation_name":"excluded_subClassOf","term_name":"PTEN hamartoma tumor syndrome","termid":"MONDO:0017623"},{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":6,"genes_by_uniquename":{"SJAG_02426":null,"SJAG_02539":null,"SJAG_03131":null,"SJAG_03153":null,"SJAG_04206":null,"SJAG_04394":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0000426"],"is_obsolete":false,"name":"Cowden disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:6457","NANDO:2200918","NCIT:C8419","OMIMPS:158350","MEDGEN:5420","MESH:D006223","NCIT:C3076","SCTID:58037000","GARD:6202","MedDRA:10051906","UMLS:C0018553"],"synonyms":[{"name":"CD","type":"related"},{"name":"Cowden disease","type":"exact"},{"name":"Cowden syndrome","type":"exact"},{"name":"Cowden's disease","type":"exact"},{"name":"MHAM","type":"related"},{"name":"dysplastic gangliocytoma of cerebellum","type":"related"},{"name":"multiple hamartoma syndrome","type":"exact"}],"termid":"MONDO:0016063","terms_by_termid":{"MONDO:0008021":null,"MONDO:0014048":null,"MONDO:0014802":null},"xrefs":{"Monarch":{"xref_id":"0016063"}}}


id: PBO:0043023
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"charged multivesicular body protein 1B","termid":"PBO:0043023"}


id: PBO:0036435
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA repair protein, SUMO-related Rad60","termid":"PBO:0036435"}


id: FYPO:0004107
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G2 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein level during vegetative growth","termid":"FYPO:0000833"},{"relation_name":"is_a","term_name":"altered protein level during vegetative growth","termid":"FYPO:0001325"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001985","FYPO:0000002","FYPO:0001312","FYPO:0006551","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"normal protein level during mitotic G2 phase","synonyms":[{"name":"normal protein accumulation during mitotic G2 phase","type":"related"},{"name":"normal protein level during G2 phase of mitotic cell cycle","type":"related"},{"name":"normal protein level during mitotic G2 phase during vegetative growth","type":"exact"}],"termid":"FYPO:0004107"}


id: MONDO:0007338
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cleft velum is a fissure type embryopathy that affects in varying degrees the soft palate.","definition_xrefs":["Orphanet:99772"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cleft palate","termid":"MONDO:0016064"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cleft soft palate","secondary_identifiers":["DOID:0110214","GARD:16907","icd11.foundation:797497023","ICD10CM:Q35.3","MEDGEN:98471","OMIM:119570","MESH:C562950","UMLS:C0432098","SCTID:253997002"],"synonyms":[{"name":"cleft soft palate","type":"exact"},{"name":"cleft velum","type":"exact"},{"name":"cleft velum palatinum","type":"exact"},{"name":"soft cleft palate","type":"exact"}],"termid":"MONDO:0007338","xrefs":{"Monarch":{"xref_id":"0007338"}}}


id: GO:1900144
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of BMP secretion.","definition_xrefs":["GOC:sart","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell communication","termid":"GO:0010647"},{"relation_name":"is_a","term_name":"positive regulation of signaling","termid":"GO:0023056"},{"relation_name":"is_a","term_name":"positive regulation of protein secretion","termid":"GO:0050714"},{"relation_name":"is_a","term_name":"regulation of BMP secretion","termid":"GO:2001284"},{"relation_name":"positively_regulates","term_name":"BMP secretion","termid":"GO:0038055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0023052","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of BMP secretion","synonyms":[{"name":"activation of BMP protein secretion","type":"narrow"},{"name":"activation of BMP secretion","type":"narrow"},{"name":"activation of bone morphogenetic protein secretion","type":"narrow"},{"name":"positive regulation of BMP protein secretion","type":"exact"},{"name":"positive regulation of bone morphogenetic protein secretion","type":"exact"},{"name":"up regulation of BMP protein secretion","type":"exact"},{"name":"up regulation of BMP secretion","type":"exact"},{"name":"up regulation of bone morphogenetic protein secretion","type":"exact"},{"name":"up-regulation of BMP protein secretion","type":"exact"},{"name":"up-regulation of BMP secretion","type":"exact"},{"name":"up-regulation of bone morphogenetic protein secretion","type":"exact"},{"name":"upregulation of BMP protein secretion","type":"exact"},{"name":"upregulation of BMP secretion","type":"exact"},{"name":"upregulation of bone morphogenetic protein secretion","type":"exact"}],"termid":"GO:1900144"}


id: PBO:0081376
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 214","termid":"PBO:0081376"}


id: PBO:0052161
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium inwardly rectifying channel subfamily J member 9","termid":"PBO:0052161"}


id: MONDO:0002366
data:
  {"annotated_genes":["SJAG_03163","SJAG_02398","SJAG_03920","SJAG_00260","SJAG_01671","SJAG_01895"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85071],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008192"},{"annotations":[86246],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011121"},{"annotations":[86156],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011544"},{"annotations":[84859],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007273"},{"annotations":[85068],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013602"},{"annotations":[86392],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032771"}]},"cv_name":"mondo","definition":"Benign and malignant neoplasms which arise from or directly involve the central or peripheral elements of the autonomic nervous system.","definition_xrefs":["NCIT:C5112"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autonomic nervous system disorder","termid":"MONDO:0001292"},{"relation_name":"is_a","term_name":"peripheral nervous system neoplasm","termid":"MONDO:0001406"},{"relation_name":"is_a","term_name":"central nervous system neoplasm","termid":"MONDO:0006130"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00260":null,"SJAG_01671":null,"SJAG_01895":null,"SJAG_02398":null,"SJAG_03163":null,"SJAG_03920":null},"genotype_count":0,"is_obsolete":false,"name":"autonomic nervous system neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:231389","DOID:2621","UMLS:C1332356"],"synonyms":[{"name":"autonomic nervous system neoplasm","type":"exact"},{"name":"autonomic nervous system neoplasm (disease)","type":"exact"},{"name":"autonomic nervous system neoplasms","type":"exact"},{"name":"autonomic nervous system tumor","type":"exact"},{"name":"autonomic nervous system tumour","type":"exact"},{"name":"neoplasm of autonomic nervous system","type":"exact"},{"name":"neoplasm of the autonomic nervous system","type":"exact"},{"name":"tumor of autonomic nervous system","type":"exact"},{"name":"tumor of the autonomic nervous system","type":"exact"},{"name":"tumour of autonomic nervous system","type":"exact"},{"name":"tumour of the autonomic nervous system","type":"exact"}],"termid":"MONDO:0002366","terms_by_termid":{"MONDO:0007273":null,"MONDO:0008192":null,"MONDO:0011121":null,"MONDO:0011544":null,"MONDO:0013602":null,"MONDO:0032771":null},"xrefs":{"Monarch":{"xref_id":"0002366"}}}


id: PBO:0068401
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNF217 antisense RNA 1 (head to head)","termid":"PBO:0068401"}


id: PBO:0059147
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MPN domain containing","termid":"PBO:0059147"}


id: PBO:0059990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND4L pseudogene 10","termid":"PBO:0059990"}


id: MONDO:0021386
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm (disease) that involves the mediastinum.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm of thorax","termid":"MONDO:0021350"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neoplasm of mediastinum","secondary_identifiers":["UMLS:C0025063","MEDGEN:44322","NCIT:C3221","ICD9:239.89","SCTID:126725000"],"synonyms":[{"name":"mediastinal neoplasm","type":"exact"},{"name":"mediastinal tumor","type":"exact"},{"name":"mediastinal tumour","type":"exact"},{"name":"mediastinum neoplasm","type":"exact"},{"name":"mediastinum neoplasm (disease)","type":"exact"},{"name":"mediastinum tumor","type":"exact"},{"name":"mediastinum tumour","type":"exact"},{"name":"neoplasm of mediastinum","type":"exact"},{"name":"neoplasm of the mediastinum","type":"exact"},{"name":"tumor of mediastinum","type":"exact"},{"name":"tumor of the mediastinum","type":"exact"},{"name":"tumour of mediastinum","type":"exact"},{"name":"tumour of the mediastinum","type":"exact"}],"termid":"MONDO:0021386","xrefs":{"Monarch":{"xref_id":"0021386"}}}


id: PBO:0078735
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Met (anticodon CAT) 7-1","termid":"PBO:0078735"}


id: PBO:0113279
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Plasma membrane transporter of the major facilitator superfamily; involved in the excretion of excess amino acids; member of the 12-spanner drug:H(+) antiporter DHA1 family; confers resistance to short-chain monocarboxylic acids and quinidine; relocalizes from plasma membrane to cytoplasm upon DNA replication stress; AQR1 has a paralog, QDR1, that arose from the whole genome duplication","termid":"PBO:0113279"}


id: PBO:0047211
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 221 member B","termid":"PBO:0047211"}


id: PR:O13783
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A programmed cell death 6-interacting protein that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar protein-sorting protein bro1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17G6.05c","secondary_identifiers":["UniProtKB:O13783"],"synonyms":[{"name":"BRO domain-containing protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPAC17G6.05c","type":"related"},{"name":"Spom972h-PDCD6IP","type":"exact"}],"termid":"PR:O13783"}


id: GO:0033407
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A triplet codon-amino acid adaptor activity that recognizes a UCA codon.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triplet codon-amino acid adaptor activity","termid":"GO:0030533"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0003723"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0060090","GO:0003723"],"is_obsolete":false,"name":"UCA codon-amino acid adaptor activity","synonyms":[{"name":"TCA codon-amino acid adaptor activity","type":"exact"},{"name":"serine tRNA","type":"related"}],"termid":"GO:0033407"}


id: GO:0042698
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rhythmic process","termid":"GO:0048511"},{"relation_name":"is_a","term_name":"multicellular organismal reproductive process","termid":"GO:0048609"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ovulation cycle","termid":"GO:0042698"}


id: PBO:0040043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARNT2 divergent transcript","termid":"PBO:0040043"}


id: GO:0045053
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.","definition_xrefs":["ISBN:0716731363"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maintenance of protein location in cell","termid":"GO:0032507"},{"relation_name":"part_of","term_name":"protein localization to Golgi apparatus","termid":"GO:0034067"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein retention in Golgi apparatus","synonyms":[{"name":"maintenance of protein location in Golgi apparatus","type":"related"},{"name":"protein-Golgi retention","type":"exact"},{"name":"retention of protein in Golgi","type":"exact"}],"termid":"GO:0045053"}


id: GO:0140082
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin = Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.","definition_xrefs":["PMID:28552615"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SUMO ligase activity","termid":"GO:0061665"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0019787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"}],"interesting_parent_ids":["GO:0140096","GO:0019787","GO:0016746","GO:0003674","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"SUMO-ubiquitin ligase activity","termid":"GO:0140082"}


id: PBO:0071371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L29 pseudogene 30","termid":"PBO:0071371"}


id: PR:Q9UT98
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pos5 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UT98"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH kinase pos5, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC323.01c","synonyms":[{"name":"Spom972h-pos5","type":"exact"}],"termid":"PR:Q9UT98"}


id: GO:0061050
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell growth","termid":"GO:0001558"},{"relation_name":"is_a","term_name":"regulation of cardiac muscle tissue growth","termid":"GO:0055021"},{"relation_name":"regulates","term_name":"cell growth involved in cardiac muscle cell development","termid":"GO:0061049"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cell growth involved in cardiac muscle cell development","termid":"GO:0061050"}


id: MONDO:0020436
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"atrial septal defect","termid":"MONDO:0006664"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"atrial septal defect, sinus venosus type","secondary_identifiers":["UMLS:C0344730","icd11.foundation:1930019148","MESH:C548009","NANDO:2200267","Orphanet:99105","SCTID:95268002","MEDGEN:138011","GARD:10696"],"synonyms":[{"name":"ASD, sinus venosus type","type":"exact"},{"name":"atrial septal defect sinus venosus","type":"related"},{"name":"sinus venosus ASD","type":"related"},{"name":"sinus venosus atrial septal defects","type":"related"}],"termid":"MONDO:0020436","xrefs":{"Monarch":{"xref_id":"0020436"}}}


id: PATO:0002319
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape with properties between those of a square and those of a circle.","definition_xrefs":["wikipedia:Squircle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"superelliptic","termid":"PATO:0002318"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"squircle","termid":"PATO:0002319"}


id: GO:0004299
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the cleavage at peptide bonds with very broad specificity.","definition_xrefs":["EC:3.4.25.1"],"gene_count":0,"genotype_count":0,"name":"obsolete proteasome endopeptidase activity (obsolete GO:0004299)","synonyms":[{"name":"multicatalytic endopeptidase","type":"related"},{"name":"proteasome","type":"related"},{"name":"proteasome endopeptidase activity","type":"exact"},{"name":"proteasome endopeptidase complex","type":"related"}],"termid":"GO:0004299"}


id: GO:1990822
data:
  {"annotated_genes":["SJAG_01636","SJAG_04715","SJAG_04983","SJAG_03256","SJAG_00051","SJAG_02716","SJAG_03400","SJAG_04725","SJAG_01336","SJAG_01923","SJAG_00877","SJAG_02029"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[63810,87649,96539,103198,103199,103200,103201],"is_not":false,"summary":null,"term":"GO:1990822"},{"annotations":[89603],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034488"},{"annotations":[93791],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034490"},{"annotations":[103009],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090518"},{"annotations":[98019,62970],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903826"},{"annotations":[96555],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0089708"},{"annotations":[103012],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090513"},{"annotations":[101982,103013],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901482"},{"annotations":[109178,103014],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090517"}]},"cv_name":"biological_process","definition":"The directed movement of basic amino acids from one side of a membrane to the other.","definition_xrefs":["GOC:dph","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid transmembrane transport","termid":"GO:0003333"},{"relation_name":"is_a","term_name":"basic amino acid transport","termid":"GO:0015802"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00051":null,"SJAG_00877":null,"SJAG_01336":null,"SJAG_01636":null,"SJAG_01923":null,"SJAG_02029":null,"SJAG_02716":null,"SJAG_03256":null,"SJAG_03400":null,"SJAG_04715":null,"SJAG_04725":null,"SJAG_04983":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"basic amino acid transmembrane transport","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000108":null},"termid":"GO:1990822","terms_by_termid":{"GO:0034488":null,"GO:0034490":null,"GO:0089708":null,"GO:0090513":null,"GO:0090517":null,"GO:0090518":null,"GO:1901482":null,"GO:1903826":null,"GO:1990822":null}}


id: PATO:0005008
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A 3-D shape inhering in a bearer by virtue of the bearer's having dentition characterized by low-crowned teeth. Human teeth are brachydont.","definition_xrefs":["DOI:10.1111/j.1469-185X.2011.00176.x"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3-D shape","termid":"PATO:0002266"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brachydont","termid":"PATO:0005008"}


id: GO:0050422
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone.","definition_xrefs":["EC:3.2.1.105","RHEA:12917"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-glucosidase activity","termid":"GO:0008422"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016798","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"strictosidine beta-glucosidase activity","secondary_identifiers":["MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN","KEGG_REACTION:R03820"],"synonyms":[{"name":"strictosidine b-glucosidase activity","type":"exact"},{"name":"strictosidine beta-D-glucohydrolase activity","type":"related"}],"termid":"GO:0050422"}


id: GO:0003256
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.","definition_xrefs":["GOC:mtg_heart"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation (obsolete GO:0003256)","termid":"GO:0003256"}


id: GO:0004694
data:
  {"annotated_genes":["SJAG_01942","SJAG_00690","SJAG_00169"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[91718,92014,108830],"is_not":false,"summary":null,"term":"GO:0004694"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.","definition_xrefs":["InterPro:IPR015516","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein serine/threonine kinase activity","termid":"GO:0004674"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00169":null,"SJAG_00690":null,"SJAG_01942":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0004672"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"}],"interesting_parent_ids":["GO:0140096","GO:0004672","GO:0016740","GO:0003824","GO:0016301","GO:0003674"],"is_obsolete":false,"name":"eukaryotic translation initiation factor 2alpha kinase activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0004694","terms_by_termid":{"GO:0004694":null}}


id: GO:0015158
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.","definition_xrefs":["GOC:mtg_transport","ISBN:0198506732","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oligosaccharide transmembrane transporter activity","termid":"GO:0015157"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"raffinose transmembrane transporter activity","synonyms":[{"name":"raffinose permease","type":"related"}],"termid":"GO:0015158"}


id: GO:0042599
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.","definition_xrefs":["Wikipedia:Lamellar_granule","GOC:jl","GOC:cjm","PMID:12243725"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secretory granule","termid":"GO:0030141"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0005575","GO:0031410","GO:0005737"],"is_obsolete":false,"name":"lamellar body","secondary_identifiers":["NIF_Subcellular:sao1379604862"],"synonyms":[{"name":"Odland body","type":"narrow"},{"name":"keratinosome","type":"narrow"},{"name":"lamellar granule","type":"exact"},{"name":"membrane-coating granule","type":"exact"}],"termid":"GO:0042599"}


id: PATO:0002246
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A force which is relative low.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"force","termid":"PATO:0001035"},{"relation_name":"is_a","term_name":"decreased object quality","termid":"PATO:0002303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased force","synonyms":[{"name":"decreased force amplitude","type":"exact"}],"termid":"PATO:0002246"}


id: PBO:0027996
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_level_during_mitotic_G2_phase","termid":"PBO:0027996"}


id: PBO:0072240
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S20 pseudogene 15","termid":"PBO:0072240"}


id: PBO:0034507
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_meiotic_homologous_chromosome_biorientation_with_abnormal_kinetochore_orientation","termid":"PBO:0034507"}


id: PBO:0082840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Constituent of the TIM23 complex; proposed alternatively to be a component of the import motor (PAM complex) or to interact with and modulate the core TIM23 (Translocase of the Inner mitochondrial Membrane) complex; protein abundance increases in response to DNA replication stress","termid":"PBO:0082840"}


id: GO:0015727
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.","definition_xrefs":["GOC:ai","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transport","termid":"GO:0015718"},{"relation_name":"is_a","term_name":"organic hydroxy compound transport","termid":"GO:0015850"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"lactate transport","termid":"GO:0015727"}


id: PBO:0027142
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histone_methyltransferase_activity","termid":"PBO:0027142"}


id: PBO:0082430
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Blocked reading frame otherwise encoding L-serine dehydratase","termid":"PBO:0082430"}


id: GO:0052151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont initiates, promotes, or enhances the normal execution of host apoptosis, leading to an increase in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:18037263","PMID:19801898","PMID:11805081","PMID:29571981"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated killing of host cell","termid":"GO:0001907"},{"relation_name":"is_a","term_name":"symbiont-mediated activation of host programmed cell death","termid":"GO:0052042"},{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host apoptosis","termid":"GO:0052150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated activation of host apoptosis","secondary_identifiers":["GO:0033669","GO:0060139","GO:0052030","GO:0039651"],"synonyms":[{"name":"activation by organism of host apoptosis","type":"exact"},{"name":"activation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"activation by symbiont of host apoptosis","type":"narrow"},{"name":"induction by organism of host apoptotic programmed cell death","type":"exact"},{"name":"induction by symbiont of host apoptosis","type":"exact"},{"name":"positive regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"positive regulation by symbiont of host apoptosis","type":"narrow"},{"name":"positive regulation by symbiont of host apoptotic process","type":"exact"},{"name":"positive regulation by virus of host apoptosis","type":"narrow"},{"name":"stimulation by symbiont of host apoptosis","type":"narrow"},{"name":"up regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"up regulation by symbiont of host apoptosis","type":"exact"},{"name":"up-regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"up-regulation by symbiont of host apoptosis","type":"exact"},{"name":"upregulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"upregulation by symbiont of host apoptosis","type":"exact"}],"termid":"GO:0052151"}


id: GO:0000431
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of transcription by galactose","termid":"GO:0000409"},{"relation_name":"is_a","term_name":"carbon catabolite regulation of transcription from RNA polymerase II promoter","termid":"GO:0000429"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0006355"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0006351","GO:0006355"],"is_obsolete":false,"name":"regulation of transcription from RNA polymerase II promoter by galactose","termid":"GO:0000431"}


id: PBO:0045509
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DSTN pseudogene 1","termid":"PBO:0045509"}


id: PBO:0066060
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAPGEF4 antisense RNA 1","termid":"PBO:0066060"}


id: GO:0034475
data:
  {"annotated_genes":["SJAG_04818","SJAG_01176","SJAG_01521","SJAG_04527","SJAG_04153","SJAG_04321","SJAG_02156","SJAG_03179","SJAG_00854","SJAG_04824","SJAG_04084"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72896,87590,92280,95118,96450,101270,101357,103584,104429,105632,117431],"is_not":false,"summary":null,"term":"GO:0034475"}]},"cv_name":"biological_process","definition":"Any process involved in forming the mature 3' end of a U4 snRNA molecule.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"snRNA 3'-end processing","termid":"GO:0034472"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00854":null,"SJAG_01176":null,"SJAG_01521":null,"SJAG_02156":null,"SJAG_03179":null,"SJAG_04084":null,"SJAG_04153":null,"SJAG_04321":null,"SJAG_04527":null,"SJAG_04818":null,"SJAG_04824":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016073"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0016073","GO:0008150"],"is_obsolete":false,"name":"U4 snRNA 3'-end processing","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"U4 snRNA 3' end processing","type":"exact"}],"termid":"GO:0034475","terms_by_termid":{"GO:0034475":null}}


id: PBO:0060185
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mucin 5AC, oligomeric mucus/gel-forming","termid":"PBO:0060185"}


id: PBO:0047368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box and leucine rich repeat protein 21, pseudogene","termid":"PBO:0047368"}


id: PBO:0060058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND5 pseudogene 5","termid":"PBO:0060058"}


id: GO:0042745
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.","definition_xrefs":["PMID:33537937","GOC:jl","PMID:26947521"],"direct_ancestors":[{"relation_name":"is_a","term_name":"circadian behavior","termid":"GO:0048512"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"circadian sleep/wake cycle","termid":"GO:0042745"}


id: MONDO:0020036
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Rare nervous system cancer.","gene_count":0,"genotype_count":0,"name":"obsolete rare nervous system tumor (obsolete MONDO:0020036)","secondary_identifiers":["Orphanet:98062"],"synonyms":[{"name":"nervous system rare tumor","type":"exact"},{"name":"rare nervous system cancer","type":"exact"},{"name":"rare nervous system neoplasm","type":"exact"}],"termid":"MONDO:0020036","xrefs":{"Monarch":{"xref_id":"0020036"}}}


id: PBO:0082037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2-dehydropantoate 2-reductase; part of the pantothenic acid pathway, structurally homologous to E. coli panE","termid":"PBO:0082037"}


id: PBO:0031570
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_septation_index","termid":"PBO:0031570"}


id: GO:0042296
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages.","definition_xrefs":["GOC:mah","PMID:12826404"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ubiquitin-like protein transferase activity","termid":"GO:0019787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0019787"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0019787","GO:0140096","GO:0003674","GO:0016746","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"ISG15 transferase activity","secondary_identifiers":["Reactome:R-HSA-5653754"],"synonyms":[{"name":"ISG15 conjugating enzyme activity","type":"narrow"}],"termid":"GO:0042296"}


id: FYPO:0001865
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) is normal. Transcription of specific genes is repressed in the presence of glucose, as in wild type.","definition_xrefs":["PomBase:mah","GO:0045014"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular response to chemical stimulus during vegetative growth","termid":"FYPO:0001318"},{"relation_name":"is_a","term_name":"transcription regulation phenotype during vegetative growth","termid":"FYPO:0001335"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001312","FYPO:0000298","FYPO:0001320"],"is_obsolete":false,"name":"normal negative regulation of transcription by glucose","synonyms":[{"name":"normal glucose repression","type":"exact"},{"name":"normal glucose repression during vegetative growth","type":"exact"},{"name":"normal glucose-sensitive transcription","type":"related"},{"name":"normal negative regulation of transcription by glucose during mitotic cell cycle","type":"related"},{"name":"normal negative regulation of transcription by glucose during vegetative growth","type":"exact"}],"termid":"FYPO:0001865"}


id: MONDO:0014510
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rhizomelic chondrodysplasia punctate that has material basis in homozygous or compound heterozygous mutation in the FAR1 gene on chromosome 11p15, which is required for the conversion of fatty acyl-CoAs to fatty alcohols, causing reduction or complete loss of FAR1 activity result in peroxisomal FAR1 deficiency.","definition_xrefs":["DOID:0081243"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"chondrodysplasia punctata","termid":"MONDO:0019701"},{"relation_name":"is_a","term_name":"fatty acyl-CoA reductase defects","termid":"MONDO:0100275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0019053"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005066","MONDO:0002525","MONDO:0019053"],"is_obsolete":false,"name":"fatty acyl-CoA reductase 1 deficiency","secondary_identifiers":["MEDGEN:863781","GARD:13319","UMLS:C4015344","Orphanet:438178","OMIM:616154"],"synonyms":[{"name":"FAR1 deficiency","type":"exact"},{"name":"PFCRD","type":"related"},{"name":"fatty acyl-CoA reductase 1 deficiency","type":"exact"},{"name":"fatty acyl-CoA reductase 1 disorder","type":"exact"},{"name":"fatty acyl-CoA reductase 1 disorder or fatty acyl-CoA reductase 1 deficiency","type":"exact"},{"name":"peroxisomal fatty acyl-CoA reductase 1 disorder","type":"related"},{"name":"rhizomelic chondrodysplasia punctata type 4","type":"exact"},{"name":"severe intellectual disability-epilepsy-cataract syndrome due to FAR1 deficiency","type":"exact"},{"name":"severe intellectual disability-epilepsy-cataract syndrome due to fatty acyl-CoA reductase 1 deficiency","type":"exact"},{"name":"severe intellectual disability-epilepsy-cataract syndrome due to peroxisomal disorder","type":"exact"}],"termid":"MONDO:0014510","xrefs":{"Monarch":{"xref_id":"0014510"}}}


id: GO:1903104
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:19853560","GOC:kmv"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of insulin receptor signaling pathway involved in determination of adult lifespan (obsolete GO:1903104)","synonyms":[{"name":"regulation of daf-2 receptor signaling pathway of determination of adult lifespan","type":"narrow"},{"name":"regulation of insulin receptor signaling pathway of determination of adult lifespan","type":"exact"},{"name":"regulation of insulin receptor signalling pathway of determination of adult lifespan","type":"exact"}],"termid":"GO:1903104"}


id: PBO:0003412
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acetolactate synthase catalytic subunit","termid":"PBO:0003412"}


id: PBO:0086379
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress","termid":"PBO:0086379"}


id: MONDO:0016047
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An infectious process affecting the internal structures of the eye.","definition_xrefs":["NCIT:C34586"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inflammatory disease","termid":"MONDO:0021166"},{"relation_name":"is_a","term_name":"eye infectious disorder","termid":"MONDO:0043885"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"endophthalmitis","secondary_identifiers":["SCTID:1847009","UMLS:C0014236","MEDGEN:8633","icd11.foundation:1211141166","GARD:20333","Orphanet:199323","ICD9:360.19","MedDRA:10014801","DOID:4692","MESH:D009877"],"termid":"MONDO:0016047","xrefs":{"Monarch":{"xref_id":"0016047"}}}


id: PBO:0067730
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 28","termid":"PBO:0067730"}


id: MONDO:0018177
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma, IDH-mutant), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma, IDH- wildtype). (Adapted from WHO)","definition_xrefs":["NCIT:C3058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"high grade astrocytic tumor","termid":"MONDO:0016680"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"glioblastoma","secondary_identifiers":["MedDRA:10018336","EFO:0000519","ONCOTREE:GBM","SCTID:393563007","DOID:3068","HP:0100843","GARD:2491","NANDO:2200087","NORD:1187","ICDO:9440/3","MESH:D005909","MEDGEN:42228","HP:0012174","ONCOTREE:GB","MedDRA:10018337","Orphanet:360","UMLS:C0017636"],"synonyms":[{"name":"GBM","type":"exact"},{"name":"GBM (glioblastoma)","type":"exact"},{"name":"WHO grade IV glioma","type":"exact"},{"name":"giant cell glioblastoma (histologic variant)","type":"related"},{"name":"glioblastoma","type":"exact"},{"name":"glioblastoma (disease)","type":"exact"},{"name":"glioblastoma multiforme","type":"exact"},{"name":"glioblastoma multiforme (disease)","type":"exact"},{"name":"gliosarcoma (histologic variant)","type":"related"},{"name":"grade IV adult astrocytic tumor","type":"narrow"},{"name":"grade IV adult astrocytic tumour","type":"narrow"},{"name":"grade IV astrocytic neoplasm","type":"exact"},{"name":"grade IV astrocytic tumor","type":"exact"},{"name":"grade IV astrocytic tumour","type":"exact"},{"name":"grade IV astrocytoma","type":"exact"},{"name":"primary glioblastoma multiforme","type":"exact"},{"name":"spongioblastoma multiforme","type":"exact"}],"termid":"MONDO:0018177","xrefs":{"Monarch":{"xref_id":"0018177"}}}


id: MONDO:0013107
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing atopic dermatitis that is associated with variation in the region 11q13.5.","definition_xrefs":["DOID:0110103","MONDO:patterns/inherited_susceptibility","PMID:19349984"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"excluded_subClassOf","term_name":"atopic eczema","termid":"MONDO:0004980"},{"relation_name":"is_a","term_name":"dermatitis, atopic, susceptibility to","termid":"MONDO:0100178"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dermatitis, atopic, 7","secondary_identifiers":["MEDGEN:414058","UMLS:C2751599","OMIM:613064","MESH:C567796"],"synonyms":[{"name":"ATOD7","type":"exact"},{"name":"atopic dermatitis 7","type":"exact"},{"name":"atopic dermatitis type 7","type":"exact"},{"name":"dermatitis, ATOPIC, 7","type":"related"},{"name":"dermatitis, atopic, susceptibility to, 7","type":"exact"}],"termid":"MONDO:0013107","xrefs":{"Monarch":{"xref_id":"0013107"}}}


id: FYPO:0003631
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which U2-type prespliceosome assembly is decreased. The U2-type prespliceosome is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP, and also contains other proteins.","definition_xrefs":["GO:1903241","GO:0071004","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal ribonucleoprotein complex assembly","termid":"FYPO:0003628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased U2-type prespliceosome assembly","synonyms":[{"name":"decreased U2-type prespliceosome assembly during mitotic cell cycle","type":"related"},{"name":"decreased U2-type prespliceosome assembly during vegetative growth","type":"exact"},{"name":"reduced U2-type prespliceosome assembly","type":"exact"}],"termid":"FYPO:0003631"}


id: FYPO:0006159
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to linear elements is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to linear element","termid":"FYPO:0000909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0000138","FYPO:0005447"],"is_obsolete":false,"name":"increased protein localization to linear element","synonyms":[{"name":"increased protein localisation to linear element","type":"exact"}],"termid":"FYPO:0006159"}


id: PBO:0086934
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi","termid":"PBO:0086934"}


id: MONDO:0005311
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.","definition_xrefs":["NCIT:C35768"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arteriosclerosis disorder","termid":"MONDO:0002277"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atherosclerosis","secondary_identifiers":["ICD9:440.8","UMLS:C0004153","EFO:0003914","MESH:D050197","SCTID:441574008","MEDGEN:13948","ICD9:440","NCIT:C35771","ICD10CM:I70","DOID:1936"],"synonyms":[{"name":"atherosclerosis artery","type":"related"},{"name":"atherosclerosis of artery","type":"exact"},{"name":"atherosclerotic cardiovascular disease","type":"exact"}],"termid":"MONDO:0005311","xrefs":{"Monarch":{"xref_id":"0005311"}}}


id: PATO:0000511
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000511 absolute disease sensitivity value (obsolete PATO:0000511)","termid":"PATO:0000511"}


id: PBO:0086500
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative plasma membrane sensor; involved in cell integrity signaling and stress response during glucose starvation and oxidative stress; has structural and functional similarity to Mid2p; MTL1 has a paralog, MID2, that arose from the whole genome duplication","termid":"PBO:0086500"}


id: GO:2000129
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of octopamine or tyramine signaling pathway","termid":"GO:2000126"},{"relation_name":"is_a","term_name":"regulation of octopamine signaling pathway","termid":"GO:2000128"},{"relation_name":"negatively_regulates","term_name":"octopamine signaling pathway","termid":"GO:0071927"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of octopamine signaling pathway","synonyms":[{"name":"negative regulation of octopamine signalling pathway","type":"exact"}],"termid":"GO:2000129"}


id: PBO:0068251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 28S ribosomal N3","termid":"PBO:0068251"}


id: GO:0018420
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues.","definition_xrefs":["RESID:AA0294"],"gene_count":0,"genotype_count":0,"name":"obsolete peptide cross-linking via N6-(L-isoaspartyl)-L-lysine (obsolete GO:0018420)","termid":"GO:0018420"}


id: MONDO:0017833
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hypereosinophilic syndrome","termid":"MONDO:0015691"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046","MONDO:0005267"],"is_obsolete":false,"name":"primary hypereosinophilic syndrome","secondary_identifiers":["UMLS:C5679898","MEDGEN:1830089","GARD:21395","Orphanet:314950"],"synonyms":[{"name":"HES-M","type":"exact"},{"name":"HES-N","type":"exact"},{"name":"clonal hypereosinophilic syndrome","type":"exact"},{"name":"neoplastic hypereosinophilic syndrome","type":"exact"},{"name":"primary HES","type":"exact"}],"termid":"MONDO:0017833","xrefs":{"Monarch":{"xref_id":"0017833"}}}


id: SO:0001950
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A kind of histone modification site, whereby the 4th residue (a lysine), from the start of the H4 protein is tri-methylated.","definition_xrefs":["EBI:nj"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone_methylation_site","termid":"SO:0001701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"H4K4_trimethylation_site","synonyms":[{"name":" H4K4me3","type":"exact"},{"name":"H4K4 trimethylation site","type":"exact"}],"termid":"SO:0001950"}


id: PBO:0029059
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-small_vacuoles_present_in_increased_numbers_during_cellular_hypotonic_response","termid":"PBO:0029059"}


id: PBO:0081855
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger family member 788, pseudogene","termid":"PBO:0081855"}


id: GO:0016630
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+.","definition_xrefs":["EC:1.3.1.33"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"protochlorophyllide reductase activity","secondary_identifiers":["MetaCyc:RXN1F-10","RHEA:11132"],"synonyms":[{"name":"NADPH-protochlorophyllide oxidoreductase activity","type":"related"},{"name":"NADPH-protochlorophyllide reductase activity","type":"related"},{"name":"NADPH2-protochlorophyllide oxidoreductase activity","type":"related"},{"name":"chlorophyllide-a:NADP+ 7,8-oxidoreductase activity","type":"related"},{"name":"protochlorophyllide oxidoreductase activity","type":"related"},{"name":"protochlorophyllide photooxidoreductase activity","type":"related"}],"termid":"GO:0016630"}


id: GO:1901169
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of 3-chlorocatechol.","definition_xrefs":["GOC:yaf","UniPathway:UPA00083","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catechol-containing compound biosynthetic process","termid":"GO:0009713"},{"relation_name":"is_a","term_name":"3-chlorocatechol metabolic process","termid":"GO:1901167"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"3-chlorocatechol biosynthetic process","synonyms":[{"name":"3-chlorocatechol anabolism","type":"exact"},{"name":"3-chlorocatechol biosynthesis","type":"exact"},{"name":"3-chlorocatechol formation","type":"exact"},{"name":"3-chlorocatechol synthesis","type":"exact"}],"termid":"GO:1901169"}


id: GO:0036531
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine.","definition_xrefs":["GOC:PARL","GOC:bf","PMID:25416785"],"gene_count":0,"genotype_count":0,"name":"obsolete glutathione deglycation (obsolete GO:0036531)","termid":"GO:0036531"}


id: MONDO:0035295
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital primary megaureter","termid":"MONDO:0018960"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"congenital primary megaureter, refluxing and obstructed form","secondary_identifiers":["MEDGEN:1843335","UMLS:C5681326","ICD10CM:Q62.2","Orphanet:544578","GARD:22236"],"termid":"MONDO:0035295","xrefs":{"Monarch":{"xref_id":"0035295"}}}


id: PBO:0005382
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase activating protein Gyp2 (predicted)","termid":"PBO:0005382"}


id: GO:0097561
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.","definition_xrefs":["PMID:16607022","ISBN:9780124260207","GOC:giardia","PMID:5961344"],"direct_ancestors":[{"relation_name":"is_a","term_name":"9+2 motile cilium","termid":"GO:0097729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"right caudal flagellum","synonyms":[{"name":"right caudal cilium","type":"exact"}],"termid":"GO:0097561"}


id: PBO:0028821
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_sporulation_resulting_in_formation_of_ascus_with_fewer_than_four_spores","termid":"PBO:0028821"}


id: PBO:0004420
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amino acid permease, predicted Meu22","termid":"PBO:0004420"}


id: PBO:0031040
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_endomembrane_system_organization","termid":"PBO:0031040"}


id: FYPO:0005084
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at ribosomal RNA (rRNA) genes is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:21151114","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to chromatin at ncRNA gene","termid":"FYPO:0005083"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000138","FYPO:0000257","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal protein localization to chromatin at rRNA gene","synonyms":[{"name":"normal protein localisation to chromatin at rRNA gene","type":"exact"},{"name":"normal protein localization to chromatin at rDNA","type":"exact"},{"name":"normal protein localization to chromatin at rRNA gene during mitotic cell cycle","type":"related"},{"name":"normal protein localization to chromatin at rRNA gene during vegetative growth","type":"exact"},{"name":"normal protein localization to chromatin at ribosomal DNA","type":"exact"}],"termid":"FYPO:0005084"}


id: PATO:0001532
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color pattern inhering in a bearer by virtue of the bearer's having one hue.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"color pattern","termid":"PATO:0000019"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mono-colored","synonyms":[{"name":"evenly colored","type":"exact"},{"name":"homogeneously colored","type":"exact"},{"name":"homogenously pigmented","type":"related"},{"name":"uniformly colored","type":"exact"}],"termid":"PATO:0001532"}


id: PBO:0057008
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 100","termid":"PBO:0057008"}


id: PBO:0045707
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dysferlin","termid":"PBO:0045707"}


id: MONDO:0957430
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"schizophrenia","termid":"MONDO:0005090"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0002039"],"is_obsolete":false,"name":"childhood-onset schizophrenia","secondary_identifiers":["UMLS:C0036346","GARD:4766","MEDGEN:48576","Orphanet:641496"],"termid":"MONDO:0957430","xrefs":{"Monarch":{"xref_id":"0957430"}}}


id: PBO:0077685
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TNF superfamily member 14","termid":"PBO:0077685"}


id: MONDO:0014300
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Proximal myopathy with extrapyramidal signs is a rare, hereditary non-dystrophic myopathy characterized by proximal muscle weakness, delayed motor development, learning difficulties, and progressive extrapyramidal motor signs including chorea, dystonia and tremor. Variable additional features have been reported - ataxia, microcephaly, ophthalmoplegia, ptosis, and optic atrophy.","definition_xrefs":["Orphanet:401768"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myopathy","termid":"MONDO:0005336"},{"relation_name":"is_a","term_name":"movement disorder","termid":"MONDO:0005395"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"},{"relation_name":"is_a","term_name":"hereditary skeletal muscle disorder","termid":"MONDO:0700223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"proximal myopathy with extrapyramidal signs","secondary_identifiers":["UMLS:C3810285","OMIM:615673","DOID:0111335","MEDGEN:816615","GARD:12978"],"synonyms":[{"name":"MPXPS","type":"related"},{"name":"myopathy with extrapyramidal signs","type":"related"}],"termid":"MONDO:0014300","xrefs":{"Monarch":{"xref_id":"0014300"}}}


id: PBO:0041482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 11 open reading frame 91","termid":"PBO:0041482"}


id: MONDO:0957253
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital diarrhea","termid":"MONDO:0000824"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"diarrhea 13","secondary_identifiers":["MEDGEN:1841113","OMIM:620357","UMLS:C5830477"],"termid":"MONDO:0957253","xrefs":{"Monarch":{"xref_id":"0957253"}}}


id: GO:0007613
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).","definition_xrefs":["ISBN:0582227089","GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"learning or memory","termid":"GO:0007611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"memory","secondary_identifiers":["Wikipedia:Memory"],"termid":"GO:0007613"}


id: FYPO:0003577
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the transport of a substance from the plasma membrane to the vacuole does not occur when the cell is subject to, or recovering from, nitrogen starvation. Transport normally occurs in two stages, plasma membrane to endosome followed by endosome to vacuole transport.","definition_xrefs":["PMID:22194353","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vacuolar transport","termid":"FYPO:0003578"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abolished plasma membrane to vacuole transport after nitrogen starvation","synonyms":[{"name":"abolished plasma membrane to vacuole protein transport after nitrogen starvation","type":"narrow"}],"termid":"FYPO:0003577"}


id: PBO:0086819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; YMR084W and adjacent ORF YMR085W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1","termid":"PBO:0086819"}


id: MOD:01806
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-leucine residue to N,N-dimethyl-L-leucine.","definition_xrefs":["RESID:AA0538","PubMed:19522542"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-amino dimethylated residue","termid":"MOD:01686"},{"relation_name":"is_a","term_name":"N-methylated leucine","termid":"MOD:01808"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"N,N-dimethyl-L-leucine","synonyms":[{"name":"(2S)-2-(dimethylamino)-4-methylpentanoic acid","type":"exact"},{"name":"2-(dimethylamino)-4-methylvaleric acid","type":"exact"},{"name":"2-(dimethylazanyl)-4-methylpentanoic acid","type":"exact"},{"name":"MOD_RES N,N-dimethylleucine","type":"exact"},{"name":"N,N-dimethyl-L-leucine","type":"exact"},{"name":"N,N-dimethylleucine","type":"exact"}],"termid":"MOD:01806"}


id: MONDO:0033551
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 72 with autoinflammation","secondary_identifiers":["DOID:0112015","MEDGEN:1749856","OMIM:618982","UMLS:C5436540"],"synonyms":[{"name":"IMD72","type":"related"},{"name":"IMMUNODEFICIENCY 72 WITH AUTOINFLAMMATION","type":"related"}],"termid":"MONDO:0033551","xrefs":{"Monarch":{"xref_id":"0033551"}}}


id: GO:1905628
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.","definition_xrefs":["GOC:PARL","GOC:pad","GOC:TermGenie","PMID:25642596","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biosynthetic process","termid":"GO:0009890"},{"relation_name":"is_a","term_name":"regulation of serotonin biosynthetic process","termid":"GO:1905627"},{"relation_name":"negatively_regulates","term_name":"serotonin biosynthetic process","termid":"GO:0042427"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of serotonin biosynthetic process","synonyms":[{"name":"down regulation of serotonin anabolism","type":"exact"},{"name":"down regulation of serotonin biosynthesis","type":"exact"},{"name":"down regulation of serotonin biosynthetic process","type":"exact"},{"name":"down regulation of serotonin formation","type":"exact"},{"name":"down regulation of serotonin synthesis","type":"exact"},{"name":"down-regulation of serotonin anabolism","type":"exact"},{"name":"down-regulation of serotonin biosynthesis","type":"exact"},{"name":"down-regulation of serotonin biosynthetic process","type":"exact"},{"name":"down-regulation of serotonin formation","type":"exact"},{"name":"down-regulation of serotonin synthesis","type":"exact"},{"name":"downregulation of serotonin anabolism","type":"exact"},{"name":"downregulation of serotonin biosynthesis","type":"exact"},{"name":"downregulation of serotonin biosynthetic process","type":"exact"},{"name":"downregulation of serotonin formation","type":"exact"},{"name":"downregulation of serotonin synthesis","type":"exact"},{"name":"inhibition of serotonin anabolism","type":"narrow"},{"name":"inhibition of serotonin biosynthesis","type":"narrow"},{"name":"inhibition of serotonin biosynthetic process","type":"narrow"},{"name":"inhibition of serotonin formation","type":"narrow"},{"name":"inhibition of serotonin synthesis","type":"narrow"},{"name":"negative regulation of serotonin anabolism","type":"exact"},{"name":"negative regulation of serotonin biosynthesis","type":"exact"},{"name":"negative regulation of serotonin formation","type":"exact"},{"name":"negative regulation of serotonin synthesis","type":"exact"}],"termid":"GO:1905628"}


id: GO:0060271
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.","definition_xrefs":["GOC:pr","ISBN:0198506732","PMID:27350441","GOC:cilia","GOC:vw","GOC:dph","GOC:BHF","GOC:kmv","PMID:13978319"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cilium organization","termid":"GO:0044782"},{"relation_name":"is_a","term_name":"organelle assembly","termid":"GO:0070925"},{"relation_name":"is_a","term_name":"plasma membrane bounded cell projection assembly","termid":"GO:0120031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"cilium assembly","secondary_identifiers":["GO:0042384"],"synonyms":[{"name":"ciliogenesis","type":"exact"},{"name":"cilium biogenesis","type":"related"},{"name":"cilium formation","type":"exact"},{"name":"cilium morphogenesis","type":"related"},{"name":"cilium organization","type":"related"},{"name":"microtubule-based flagellum assembly","type":"exact"}],"termid":"GO:0060271"}


id: GO:0097610
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates.","definition_xrefs":["GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cell surface","termid":"GO:0009986"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0009986"}],"interesting_parent_ids":["GO:0009986","GO:0005575"],"is_obsolete":false,"name":"cell surface furrow","synonyms":[{"name":"cell surface groove","type":"related"},{"name":"furrow","type":"broad"},{"name":"groove","type":"broad"}],"termid":"GO:0097610"}


id: PBO:0056032
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukotriene A4 hydrolase","termid":"PBO:0056032"}


id: GO:0097146
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.","definition_xrefs":["PMID:14634621","GOC:so"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Bcl-2 family protein complex","termid":"GO:0097136"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"NOXA-BCL-xl complex","termid":"GO:0097146"}


id: GO:0018479
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.","definition_xrefs":["EC:1.2.1.28"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aldehyde dehydrogenase (NAD+) activity","termid":"GO:0004029"},{"relation_name":"is_a","term_name":"benzaldehyde dehydrogenase [NAD(P)+] activity","termid":"GO:0019115"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"benzaldehyde dehydrogenase (NAD+) activity","secondary_identifiers":["MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN","UM-BBD_reactionID:r0269","RHEA:11840"],"synonyms":[{"name":"benzaldehyde (NAD) dehydrogenase activity","type":"related"},{"name":"benzaldehyde:NAD+ oxidoreductase activity","type":"related"}],"termid":"GO:0018479"}


id: PATO:0001989
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A curvature quality inhering in a bearer by virtue of the bearer's having many curves and turns.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"curvature","termid":"PATO:0001591"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sinuous","synonyms":[{"name":"twisted","type":"related"}],"termid":"PATO:0001989"}


id: PBO:0004096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotic cohesin complex subunit Psm1","termid":"PBO:0004096"}


id: PBO:0044206
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cathepsin L pseudogene 4","termid":"PBO:0044206"}


id: PBO:0089528
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 snoRNA associated protein Dip2","termid":"PBO:0089528"}


id: GO:0050732
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein phosphorylation","termid":"GO:0001933"},{"relation_name":"is_a","term_name":"regulation of peptidyl-tyrosine phosphorylation","termid":"GO:0050730"},{"relation_name":"negatively_regulates","term_name":"peptidyl-tyrosine phosphorylation","termid":"GO:0018108"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of peptidyl-tyrosine phosphorylation","synonyms":[{"name":"down regulation of peptidyl-tyrosine phosphorylation","type":"exact"},{"name":"down-regulation of peptidyl-tyrosine phosphorylation","type":"exact"},{"name":"downregulation of peptidyl-tyrosine phosphorylation","type":"exact"},{"name":"inhibition of peptidyl-tyrosine phosphorylation","type":"narrow"}],"termid":"GO:0050732"}


id: MONDO:0020672
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder characterized by occlusion of blood vessels. It differs from thrombosis in that it can be used to describe any form of blockage, not just one formed by a clot.","definition_xrefs":["Wikipedia:Vascular_occlusion"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vascular disorder","termid":"MONDO:0005385"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vascular occlusion disorder","synonyms":[{"name":"vascular occlusion","type":"exact"}],"termid":"MONDO:0020672","xrefs":{"Monarch":{"xref_id":"0020672"}}}


id: SO:0001922
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A scaffold composed of mitochondrial contigs.","definition_xrefs":["GMOD:ea"],"direct_ancestors":[{"relation_name":"is_a","term_name":"supercontig","termid":"SO:0000148"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial_supercontig","synonyms":[{"name":"mitochondrial scaffold","type":"exact"},{"name":"mitochondrial supercontig","type":"exact"},{"name":"mitochondrial_scaffold","type":"exact"}],"termid":"SO:0001922"}


id: PBO:0088520
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial carrier, 2-oxoadipate/2-oxoglutarate","termid":"PBO:0088520"}


id: GO:1990113
data:
  {"annotated_genes":["SJAG_04093","SJAG_04012"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[105645,117183],"is_not":false,"summary":null,"term":"GO:1990113"}]},"cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.","definition_xrefs":["PMID:23459708","GOC:rb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04012":null,"SJAG_04093":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0065003","GO:0008150","GO:0044085"],"is_obsolete":false,"name":"RNA polymerase I assembly","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"DNA-directed RNA polymerase I complex assembly","type":"exact"},{"name":"RNA Polymerase I complex assembly","type":"exact"}],"termid":"GO:1990113","terms_by_termid":{"GO:1990113":null}}


id: GO:0005607
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.","definition_xrefs":["PMID:10842354","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"laminin complex","termid":"GO:0043256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"laminin-2 complex","synonyms":[{"name":"laminin-211 complex","type":"exact"}],"termid":"GO:0005607"}


id: PBO:0091017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudouridine-5'-phosphatase Pud1","termid":"PBO:0091017"}


id: PR:O14279
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rrp14 gene.","definition_xrefs":["UniProtKB:O14279","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal RNA-processing protein 14-N (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC8C9.10c","synonyms":[{"name":"Spom972h-rrp14","type":"exact"},{"name":"ribosome biogenesis protein rrp14-N (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14279"}


id: PBO:0053357
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 261","termid":"PBO:0053357"}


id: GO:0032497
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.","definition_xrefs":["GOC:add","PMID:15998797"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of molecule of bacterial origin","termid":"GO:0032490"},{"relation_name":"is_a","term_name":"response to lipopolysaccharide","termid":"GO:0032496"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of lipopolysaccharide","synonyms":[{"name":"detection of LPS","type":"exact"}],"termid":"GO:0032497"}


id: PBO:0088778
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin cortical patch component Lsb4","termid":"PBO:0088778"}


id: PBO:0109132
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CRIPTO pseudogene 5","termid":"PBO:0109132"}


id: FYPO:0007316
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the amount of any macromolecular complex present in a cell differs from wild type.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered level of substance in cell","termid":"FYPO:0000989"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"altered level of macromolecular complex","synonyms":[{"name":"abnormal level of macromolecular complex","type":"exact"}],"termid":"FYPO:0007316"}


id: PBO:0052320
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KIAA1210","termid":"PBO:0052320"}


id: PBO:0079703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBOX5 antisense RNA 1","termid":"PBO:0079703"}


id: MONDO:0017615
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A genetic epileptic syndrome characterized by the occurrence of afebrile repeated seizures in healthy infants, between the third and eighth month of life.","definition_xrefs":["Orphanet:306"],"direct_ancestors":[{"relation_name":"is_a","term_name":"infancy electroclinical syndrome","termid":"MONDO:0000413"},{"relation_name":"is_a","term_name":"benign partial infantile seizures","termid":"MONDO:0015642"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"benign familial infantile epilepsy","secondary_identifiers":["UMLS:C5575231","GARD:857","DOID:0060169","OMIMPS:601764","ICD9:V17.2","SCTID:230410004","icd11.foundation:1944845279","MEDGEN:1806836"],"synonyms":[{"name":"BFIC","type":"exact"},{"name":"BFIE","type":"exact"},{"name":"BFIS","type":"exact"},{"name":"benign familial infantile convulsion","type":"exact"},{"name":"benign familial infantile convulsions","type":"exact"},{"name":"benign familial infantile seizures","type":"exact"},{"name":"seizures, benign familial infantile","type":"exact"}],"termid":"MONDO:0017615","xrefs":{"Monarch":{"xref_id":"0017615"}}}


id: PBO:0079105
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TSC22 domain family member 1","termid":"PBO:0079105"}


id: PR:Q7Z9I1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pfl4 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q7Z9I1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell agglutination protein C188.09c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC188.09c","synonyms":[{"name":"Spom972h-pfl4","type":"exact"}],"termid":"PR:Q7Z9I1"}


id: PBO:0031340
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_N-ethylmaleimide","termid":"PBO:0031340"}


id: GO:0050986
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.","definition_xrefs":["RESID:AA0360","PMID:14531691"],"gene_count":0,"genotype_count":0,"name":"obsolete isopeptide cross-linking via N-(L-isoglutamyl)-glycine (obsolete GO:0050986)","termid":"GO:0050986"}


id: MONDO:0007419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Darwinian tubercle of pinna (obsolete MONDO:0007419)","termid":"MONDO:0007419","xrefs":{"Monarch":{"xref_id":"0007419"}}}


id: MONDO:0018518
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete adenocarcinoma of the anal canal (obsolete MONDO:0018518)","termid":"MONDO:0018518","xrefs":{"Monarch":{"xref_id":"0018518"}}}


id: FYPO:0000625
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which premeiotic DNA replication is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA replication","termid":"FYPO:0000217"},{"relation_name":"is_a","term_name":"abnormal meiotic cell cycle process","termid":"FYPO:0002739"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000293"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0005447","FYPO:0001985","FYPO:0000293","FYPO:0000002"],"is_obsolete":false,"name":"abnormal premeiotic DNA replication","synonyms":[{"name":"abnormal meiotic DNA replication","type":"related"},{"name":"abnormal meiotic DNA synthesis","type":"related"},{"name":"abnormal premeiotic DNA synthesis","type":"related"}],"termid":"FYPO:0000625"}


id: PBO:0030291
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cell_population_growth_on_glucose_carbon_source","termid":"PBO:0030291"}


id: PBO:0083782
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential protein, constituent of 66S pre-ribosomal particles; interacts with proteins involved in ribosomal biogenesis and cell polarity; member of the SURF-6 family","termid":"PBO:0083782"}


id: PBO:0043475
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCR4-NOT transcription complex subunit 11","termid":"PBO:0043475"}


id: GO:0002864
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of acute inflammatory response","termid":"GO:0002673"},{"relation_name":"is_a","term_name":"regulation of inflammatory response to antigenic stimulus","termid":"GO:0002861"},{"relation_name":"regulates","term_name":"acute inflammatory response to antigenic stimulus","termid":"GO:0002438"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of acute inflammatory response to antigenic stimulus","termid":"GO:0002864"}


id: PBO:0087805
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tap42p-interacting protein; negative regulator of the TORC1 signaling pathway that activates the type 2A-related phosphatase Sit4p by binding and antagonizing Tap42p, a SIT4 inhibitor; proposed to be part of a feedback loop to amplify Sit4p activity when TORC1 is inactivated; protein abundance increases in response to DNA replication stress","termid":"PBO:0087805"}


id: PBO:0056692
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic double-stranded break formation protein 4","termid":"PBO:0056692"}


id: PATO:0000721
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000721 absolute yield value (obsolete PATO:0000721)","termid":"PATO:0000721"}


id: GO:0003357
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron differentiation","termid":"GO:0030182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"noradrenergic neuron differentiation","synonyms":[{"name":"norepinephrine secreting neuron differentiation","type":"exact"}],"termid":"GO:0003357"}


id: MONDO:0000576
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete CD3delta deficiency (obsolete MONDO:0000576)","termid":"MONDO:0000576","xrefs":{"Monarch":{"xref_id":"0000576"}}}


id: PBO:0057452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 571","termid":"PBO:0057452"}


id: PBO:0070048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6atac small nuclear 5, pseudogene","termid":"PBO:0070048"}


id: MONDO:0011505
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypobetalipoproteinemia in which the cause of the disease is a mutation in the ANGPTL3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypobetalipoproteinemia","termid":"MONDO:0017774"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002525"],"is_obsolete":false,"name":"familial hypobetalipoproteinemia 2","secondary_identifiers":["MESH:C565732","GARD:15376","MEDGEN:341895","OMIM:605019","UMLS:C1857970","DOID:0111061"],"synonyms":[{"name":"ANGPTL3 hypobetalipoproteinemia","type":"exact"},{"name":"FHBL2","type":"exact"},{"name":"combined familial hypolipidemia","type":"exact"},{"name":"familial hypobetalipoproteinemia 2","type":"exact"},{"name":"familial hypobetalipoproteinemia type 2","type":"exact"},{"name":"hypobetalipoproteinemia caused by mutation in ANGPTL3","type":"exact"},{"name":"hypobetalipoproteinemia, familial, 2","type":"related"},{"name":"hypobetalipoproteinemia, familial, type 2","type":"exact"},{"name":"hypolipidemia, familial, combined","type":"related"}],"termid":"MONDO:0011505","xrefs":{"Monarch":{"xref_id":"0011505"}}}


id: GO:0003343
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.","definition_xrefs":["GOC:dph","PMID:18722343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesenchyme development","termid":"GO:0060485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"septum transversum development","termid":"GO:0003343"}


id: GO:0072535
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tumor necrosis factor superfamily cytokine production","termid":"GO:0071706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"tumor necrosis factor (ligand) superfamily member 11 production","synonyms":[{"name":"RANKL production","type":"exact"},{"name":"TNFSF11 production","type":"exact"},{"name":"tumor necrosis factor ligand superfamily member 11 production","type":"exact"}],"termid":"GO:0072535"}


id: PBO:0036211
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-two_Mei2_nuclear_dots_present_in_cell","termid":"PBO:0036211"}


id: PBO:0005376
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor TFIID complex subunit 8 (predicted)","termid":"PBO:0005376"}


id: FYPO:0001292
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of CDP-diacylglycerol-serine O-phosphatidyltransferase activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal CDP-diacylglycerol-serine O-phosphatidyltransferase activity","termid":"FYPO:0001291"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000707","FYPO:0001985","FYPO:0000661","FYPO:0000652"],"is_obsolete":false,"name":"decreased CDP-diacylglycerol-serine O-phosphatidyltransferase activity","synonyms":[{"name":"reduced CDP-diacylglycerol-serine O-phosphatidyltransferase activity","type":"exact"}],"termid":"FYPO:0001292"}


id: PATO:0002073
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A molecular quality that arises from the synergistic strength of bond affinities between multiple bond interactions.","definition_xrefs":["Wikipedia:Wikipedia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molecular quality","termid":"PATO:0002182"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"avidity","termid":"PATO:0002073"}


id: MONDO:0014644
data:
  {"annotated_genes":["SJAG_02306"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84341],"is_not":false,"summary":null,"term":"MONDO:0014644"}]},"cv_name":"mondo","definition":"Autosomal recessive spastic paraplegia type 74 is a rare, genetic, spastic paraplegia-optic atrophy-neuropathy-related (SPOAN-like) disorder characterized by childhood onset of mild to moderate spastic paraparesis which manifests with gait impairment that very slowly progresses into late adulthood, hyperactive patellar reflex and bilateral extensor plantar response, in association with optic atrophy and typical symptoms of peripheral neuropathy, including reduced or absent ankle reflexes, lower limb atrophy and distal sensory impairment. Reduced visual acuity and pes cavus are frequently reported.","definition_xrefs":["Orphanet:468661"],"direct_ancestors":[{"relation_name":"is_a","term_name":"complex hereditary spastic paraplegia","termid":"MONDO:0015150"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02306":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"hereditary spastic paraplegia 74","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1800260","DOID:0110819","OMIM:616451","UMLS:C5568837","GARD:17842"],"synonyms":[{"name":"IBA57 hereditary spastic paraplegia","type":"exact"},{"name":"SPG74","type":"exact"},{"name":"autosomal recessive spastic paraplegia 74","type":"exact"},{"name":"autosomal recessive spastic paraplegia type 74","type":"related"},{"name":"hereditary spastic paraplegia caused by mutation in IBA57","type":"exact"},{"name":"hereditary spastic paraplegia type 74","type":"exact"},{"name":"spastic paraplegia 74, autosomal recessive","type":"related"}],"termid":"MONDO:0014644","terms_by_termid":{"MONDO:0014644":null},"xrefs":{"Monarch":{"xref_id":"0014644"}}}


id: PBO:0005048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hexose transporter Ght6","termid":"PBO:0005048"}


id: MONDO:1010952
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Embryonal rhabdomyosarcoma that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bovine neoplasm","termid":"MONDO:0700134"},{"relation_name":"is_a","term_name":"embryonal rhabdomyosarcoma, non-human animal","termid":"MONDO:1010216"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"embryonal rhabdomyosarcoma, cattle","secondary_identifiers":["OMIA:001921-9913"],"termid":"MONDO:1010952","xrefs":{"Monarch":{"xref_id":"1010952"}}}


id: FYPO:0007209
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which cohesion between sister chromatids is decreased along the length of the chromosome arms during interphase of the mitotic cell cycle.","definition_xrefs":["PMID:31483748","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic sister chromatid cohesion","termid":"FYPO:0006521"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0000631","FYPO:0000641"],"is_obsolete":false,"name":"decreased sister chromatid cohesion along chromosome arms during mitotic interphase","synonyms":[{"name":"decreased mitotic sister chromatid cohesion along chromosome arms during interphase","type":"exact"},{"name":"decreased sister chromatid cohesion along chromosome arms during interphase of mitotic cell cycle","type":"exact"},{"name":"decreased sister chromatid cohesion along chromosome arms during mitotic interphase during vegetative growth","type":"exact"},{"name":"reduced sister chromatid cohesion along chromosome arms during mitotic interphase","type":"exact"}],"termid":"FYPO:0007209"}


id: PBO:0048725
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycosyltransferase 8 domain containing 1","termid":"PBO:0048725"}


id: GO:0052212
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by one of the organisms, where the two organisms are in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction (obsolete GO:0052212)","synonyms":[{"name":"modification of host morphology or physiology via effector molecule","type":"narrow"},{"name":"modification of host morphology or physiology via ellicitor","type":"narrow"},{"name":"modification of morphology or physiology of other organism via secreted substance during symbiotic interaction","type":"related"}],"termid":"GO:0052212"}


id: FYPO:0002810
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the septation index is normal (i.e. indistinguishable from wild type) in a population in stationary phase. The septation index is the proportion of the population undergoing septation at any given time.","definition_xrefs":["PomBase:mah","PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal septation index","termid":"FYPO:0001903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0000257"],"is_obsolete":false,"name":"normal septation index in stationary phase","synonyms":[{"name":"normal septation in stationary phase","type":"related"},{"name":"normal septation index during stationary phase","type":"exact"}],"termid":"FYPO:0002810"}


id: PBO:0002416
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription elongation factor Spt6 (predicted)","termid":"PBO:0002416"}


id: MONDO:0011188
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An arrhythmogenic right ventricular dysplasia associated with variation in the region 14q12-q22.","definition_xrefs":["DOID:0110072","PMID:8824801"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated arrhythmogenic right ventricular dysplasia","termid":"MONDO:0016342"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"arrhythmogenic right ventricular dysplasia 3","secondary_identifiers":["UMLS:C1865882","MEDGEN:356108","MESH:C566584","OMIM:602086"],"synonyms":[{"name":"ARVC3","type":"exact"},{"name":"ARVD3","type":"exact"},{"name":"arrhythmogenic right ventricular cardiomyopathy 3","type":"exact"},{"name":"arrhythmogenic right ventricular dysplasia type 3","type":"exact"},{"name":"arrhythmogenic right ventricular dysplasia, familial, 3","type":"related"},{"name":"familial arrhythmogenic right ventricular dysplasia 3","type":"exact"}],"termid":"MONDO:0011188","xrefs":{"Monarch":{"xref_id":"0011188"}}}


id: GO:0070090
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular anatomical structure","termid":"GO:0005622"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"metaphase plate","termid":"GO:0070090"}


id: PBO:0035852
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_cytoplasmic_microtubule_nucleation_during_mitotic_interphase","termid":"PBO:0035852"}


id: PBO:0043395
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-X9-C motif containing 2","termid":"PBO:0043395"}


id: GO:0046282
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cinnamic acid ester metabolic process","termid":"GO:0009801"},{"relation_name":"is_a","term_name":"phenylpropanoid catabolic process","termid":"GO:0046271"},{"relation_name":"is_a","term_name":"olefinic compound catabolic process","termid":"GO:0120256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"cinnamic acid ester catabolic process","synonyms":[{"name":"cinnamic acid ester breakdown","type":"exact"},{"name":"cinnamic acid ester catabolism","type":"exact"},{"name":"cinnamic acid ester degradation","type":"exact"}],"termid":"GO:0046282"}


id: MONDO:0000415
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An electroclinical syndrome with onset in adolescence and adulthood.","definition_xrefs":["DOID:0050705","PMID:20196795"],"direct_ancestors":[{"relation_name":"is_a","term_name":"electroclinical syndrome","termid":"MONDO:0000411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"adolescence-adult electroclinical syndrome","termid":"MONDO:0000415","xrefs":{"Monarch":{"xref_id":"0000415"}}}


id: PBO:0084200
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Histone variant H2AZ; exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin; Htz1p-containing nucleosomes facilitate RNA Pol II passage by affecting correct assembly and modification status of RNA Pol II elongation complexes and by favoring efficient nucleosome remodeling","termid":"PBO:0084200"}


id: MONDO:1012437
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"fluoroquinolone-induced retinal degeneration, non-human animal","termid":"MONDO:1011994"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fluoroquinolone-induced retinal degeneration, domestic cat","secondary_identifiers":["OMIA:001707-9685"],"termid":"MONDO:1012437","xrefs":{"Monarch":{"xref_id":"1012437"}}}


id: PBO:0011515
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"galactose specific flocculin Gsf2","termid":"PBO:0011515"}


id: GO:0050468
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-reticuline + O2 = (S)-scoulerine + H2O2 + H+. Also acts on related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)- tetrahydroprotoberberines.","definition_xrefs":["RHEA:19885"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor","termid":"GO:0046993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"reticuline oxidase activity","secondary_identifiers":["EC:1.21.3.3","KEGG_REACTION:R03831","MetaCyc:RETICULINE-OXIDASE-RXN"],"synonyms":[{"name":"(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)","type":"related"},{"name":"BBE","type":"related"},{"name":"berberine bridge enzyme activity","type":"related"},{"name":"berberine-bridge-forming enzyme activity","type":"related"},{"name":"tetrahydroprotoberberine synthase activity","type":"related"}],"termid":"GO:0050468"}


id: PBO:0002089
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"renal tubular acidosis","termid":"PBO:0002089"}


id: GO:0097660
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.","definition_xrefs":["GOC:jd","GOC:vw","PMID:9346238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SCF ubiquitin ligase complex","termid":"GO:0019005"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"SCF-Cdc4 ubiquitin ligase complex","termid":"GO:0097660"}


id: PBO:0060170
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"maturin, neural progenitor differentiation regulator homolog","termid":"PBO:0060170"}


id: PBO:0066729
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 26","termid":"PBO:0066729"}


id: FYECO:0000283
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which hemin was added to the medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ hemin","secondary_identifiers":["PMID:7565608"],"termid":"FYECO:0000283"}


id: GO:0019788
data:
  {"annotated_genes":["SJAG_01018"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[117517],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061654"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ubiquitin-like protein transferase activity","termid":"GO:0019787"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01018":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0019787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0140096","GO:0003824","GO:0016740","GO:0019787","GO:0003674","GO:0016746"],"is_obsolete":false,"name":"NEDD8 transferase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0019945","Reactome:R-HSA-8951661","Reactome:R-HSA-8951648","Reactome:R-HSA-8951764","Reactome:R-HSA-8952044","Reactome:R-HSA-8952618","Reactome:R-HSA-8952638","GO:0042295","Reactome:R-HSA-8952631","Reactome:R-HSA-8952626","Reactome:R-HSA-8956025","GO:0016976"],"synonyms":[{"name":"Hub1 conjugating enzyme activity","type":"related"},{"name":"NEDD8 conjugating enzyme activity","type":"related"},{"name":"RUB1 conjugating enzyme activity","type":"related"}],"termid":"GO:0019788","terms_by_termid":{"GO:0061654":null}}


id: GO:0048052
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"compound eye photoreceptor cell differentiation","termid":"GO:0001751"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"R1/R6 cell differentiation","termid":"GO:0048052"}


id: PBO:0044303
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome b5 type B","termid":"PBO:0044303"}


id: GO:0032774
data:
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id: MONDO:0010374
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A retinitis pigmentosa that has material basis in variation in the chromosome region Xq28.","definition_xrefs":["DOID:0110417","PMID:16740911"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinitis pigmentosa","termid":"MONDO:0019200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005328","MONDO:0005066"],"is_obsolete":false,"name":"retinitis pigmentosa 34","secondary_identifiers":["ICD10CM:H35.5","UMLS:C1845104","MEDGEN:375582","MESH:C564475","OMIM:300605","GARD:10390"],"synonyms":[{"name":"RP 34","type":"related"},{"name":"RP34","type":"exact"},{"name":"retinitis pigmentosa 34","type":"exact"},{"name":"retinitis pigmentosa type 34","type":"exact"}],"termid":"MONDO:0010374","xrefs":{"Monarch":{"xref_id":"0010374"}}}


id: FYPO:0007729
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is decreased during anaphase.","definition_xrefs":["PomBase:mah","PMID:16920624"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to mitotic spindle","termid":"FYPO:0002825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"decreased protein localization to mitotic spindle during anaphase","synonyms":[{"name":"decreased protein localisation to mitotic spindle during anaphase","type":"exact"},{"name":"decreased protein localization to elongating mitotic spindle","type":"related"},{"name":"decreased protein localization to mitotic spindle during anaphase during vegetative growth","type":"exact"},{"name":"decreased protein localization to spindle during anaphase of mitotic cell cycle","type":"related"},{"name":"decreased protein localization to spindle during mitotic anaphase","type":"exact"},{"name":"reduced protein localization to mitotic spindle during anaphase","type":"exact"}],"termid":"FYPO:0007729"}


id: GO:0075109
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process by which a symbiont alters or subverts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host signal transduction pathway","termid":"GO:0052027"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host receptor-mediated signal transduction","synonyms":[{"name":"perturbation of host receptor-mediated signal transduction","type":"exact"}],"termid":"GO:0075109"}


id: GO:1990073
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).","definition_xrefs":["ISBN:0471245194","GOC:PO_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cell wall","termid":"GO:0005618"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005618"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005618"],"is_obsolete":false,"name":"perforation plate","termid":"GO:1990073"}


id: MONDO:0002498
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete glioblastoma multiforme (obsolete MONDO:0002498)","synonyms":[{"name":"obsolete glioblastoma multiforme (disease)","type":"exact"}],"termid":"MONDO:0002498","xrefs":{"Monarch":{"xref_id":"0002498"}}}


id: PBO:0000102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-coding RNA, poly(A)-bearing RNA (predicted)","termid":"PBO:0000102"}


id: PBO:0074349
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMAD3 associated long non-coding RNA","termid":"PBO:0074349"}


id: GO:0005228
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.","definition_xrefs":["GOC:mtg_transport","PMID:12628167"],"direct_ancestors":[{"relation_name":"is_a","term_name":"potassium channel activity","termid":"GO:0005267"},{"relation_name":"is_a","term_name":"monoatomic ion-gated channel activity","termid":"GO:0022839"},{"relation_name":"is_a","term_name":"ligand-gated monoatomic cation channel activity","termid":"GO:0099094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"intracellular sodium-activated potassium channel activity","synonyms":[{"name":"intracellular sodium activated potassium channel activity","type":"exact"}],"termid":"GO:0005228"}


id: GO:0140852
data:
  {"annotated_genes":["SJAG_03006","SJAG_00341","SJAG_02319"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[117969,115347],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140850"},{"annotations":[93551],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140851"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of ubiquitin to a histone substrate.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ubiquitin protein ligase activity","termid":"GO:0061630"},{"relation_name":"is_a","term_name":"histone modifying activity","termid":"GO:0140993"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00341":null,"SJAG_02319":null,"SJAG_03006":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0004842"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0019787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016746","GO:0019787","GO:0004842","GO:0140096","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"histone ubiquitin ligase activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0140852","terms_by_termid":{"GO:0140850":null,"GO:0140851":null}}


id: PBO:0046517
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER lipid raft associated 1","termid":"PBO:0046517"}


id: GO:0015138
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dicarboxylic acid transmembrane transporter activity","termid":"GO:0005310"},{"relation_name":"is_a","term_name":"C4-dicarboxylate transmembrane transporter activity","termid":"GO:0015556"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"fumarate transmembrane transporter activity","synonyms":[{"name":"dicarboxylate (succinate/fumarate/malate) antiporter activity","type":"related"}],"termid":"GO:0015138"}


id: MONDO:0001972
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A brucellosis that involves an infection caused by Brucella melitensis [NCBITaxon:29459] in cattle, goats, sheep and humans. The disease has symptom fever, has symptom malaise, has symptom anorexia, has symptom limb pain and has symptom back pain.","definition_xrefs":["DOID:14456"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brucellosis","termid":"MONDO:0005683"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Brucella melitensis brucellosis","secondary_identifiers":["MEDGEN:549869","SCTID:427999003","ICD9:023.0","UMLS:C0302362"],"termid":"MONDO:0001972","xrefs":{"Monarch":{"xref_id":"0001972"}}}


id: PBO:0073716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S-phase kinase associated protein 1 pseudogene 3","termid":"PBO:0073716"}


id: MONDO:0008191
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete human papillomavirus type 18 integration site 2 (obsolete MONDO:0008191)","secondary_identifiers":["OMIM:167960"],"termid":"MONDO:0008191","xrefs":{"Monarch":{"xref_id":"0008191"}}}


id: MOD:01510
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-histidine residue","termid":"MOD:00909"},{"relation_name":"is_a","term_name":"iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue","termid":"MOD:01506"},{"relation_name":"is_a","term_name":"iTRAQ4plex reporter+balance reagent N-acylated residue","termid":"MOD:01709"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ4plex-117 reporter+balance reagent N'-acylated histidine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"iTRAQ4plex","type":"related"}],"termid":"MOD:01510"}


id: PBO:0004521
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"6.1.1.21","termid":"PBO:0004521"}


id: PBO:0087469
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex; subunit of Gtr1-Gtr2, a GTPase that activates TORC1 in response to amino acid stimulation; subunit of EGO/GSE, a vacuolar/endosomal membrane complex that regulates exit from rapamycin-induced growth arrest and sorting of Gap1p from the endosome to the plasma membrane; involved in phosphate transport and telomeric chromatin silencing; activated by the the Iml1p (GAP) subunit of the SEACIT complex; similar to human RagA and RagB","termid":"PBO:0087469"}


id: GO:0008919
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.","definition_xrefs":["EC:2.4.1.58"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016757"}],"interesting_parent_ids":["GO:0003824","GO:0016757","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"lipopolysaccharide glucosyltransferase I activity","secondary_identifiers":["MetaCyc:RXN0-5126","RHEA:30015"],"synonyms":[{"name":"LPS glucosyltransferase I activity","type":"exact"},{"name":"UDP-glucose:lipopolysaccharide glucosyltransferase activity","type":"related"},{"name":"UDPglucose:lipopolysaccharide glucosyltransferase I","type":"related"},{"name":"UDPglucose:lipopolysaccharide glucosyltransferase activity","type":"related"},{"name":"lipopolysaccharide glucosyltransferase activity","type":"related"},{"name":"uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I","type":"related"},{"name":"uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity","type":"related"}],"termid":"GO:0008919"}


id: PBO:0044168
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cap binding complex dependent translation initiation factor","termid":"PBO:0044168"}


id: GO:0034839
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete menth-2-enone hydratase activity (obsolete GO:0034839)","termid":"GO:0034839"}


id: GO:0045950
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that inhibits or decreases the rate of DNA recombination during mitosis.","definition_xrefs":["GOC:go_curators","GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mitotic recombination","termid":"GO:0000019"},{"relation_name":"is_a","term_name":"negative regulation of DNA recombination","termid":"GO:0045910"},{"relation_name":"negatively_regulates","term_name":"mitotic recombination","termid":"GO:0006312"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006310"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"negatively_regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006310"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0006310"],"is_obsolete":false,"name":"negative regulation of mitotic recombination","synonyms":[{"name":"down regulation of mitotic recombination","type":"exact"},{"name":"down-regulation of mitotic recombination","type":"exact"},{"name":"downregulation of mitotic recombination","type":"exact"},{"name":"inhibition of mitotic recombination","type":"narrow"},{"name":"negative regulation of recombination within rDNA repeats","type":"narrow"}],"termid":"GO:0045950"}


id: MONDO:0000944
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"arterial occlusion","termid":"MONDO:0020673"},{"relation_name":"is_a","term_name":"cerebral artery stenosis","termid":"MONDO:1040016"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebral artery occlusion","secondary_identifiers":["MEDGEN:507994","SCTID:20059004","UMLS:C0028790","ICD9:434.91","DOID:10127","ICD9:434.9","ICD9:434.90","ICD9:434"],"termid":"MONDO:0000944","xrefs":{"Monarch":{"xref_id":"0000944"}}}


id: GO:0018079
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The addition of a halogen to a protein amino acid.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete protein halogenation (obsolete GO:0018079)","synonyms":[{"name":"protein amino acid halogenation","type":"exact"}],"termid":"GO:0018079"}


id: GO:0047902
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.","definition_xrefs":["MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN","EC:3.5.1.8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0016810","GO:0003674"],"is_obsolete":false,"name":"formylaspartate deformylase activity","secondary_identifiers":["RHEA:22040"],"synonyms":[{"name":"N-formyl-L-aspartate amidohydrolase activity","type":"related"},{"name":"formylaspartic formylase (formylase I, formylase II)","type":"related"}],"termid":"GO:0047902"}


id: PBO:0057223
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 379","termid":"PBO:0057223"}


id: PBO:0027302
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_level_during_cellular_response_to_mercury_ion","termid":"PBO:0027302"}


id: PBO:0057840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3155b","termid":"PBO:0057840"}


id: PBO:0083453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CYC8","termid":"PBO:0083453"}


id: PBO:0061747
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NXT1 antisense RNA 1","termid":"PBO:0061747"}


id: PBO:0058742
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6866","termid":"PBO:0058742"}


id: PBO:0068866
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 106, pseudogene","termid":"PBO:0068866"}


id: MONDO:0005186
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A psychologically and socially impaired state, with or without physiological changes, that develops as a result of using cocaine and which leads to compulsive behaviors to acquire the substance.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"drug dependence","termid":"MONDO:0005303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cocaine dependence","secondary_identifiers":["DOID:9975","SCTID:31956009","UMLS:C0600427","MEDGEN:154705","icd11.foundation:1691013484","ICD9:304.2","EFO:0002610","ICD9:304.20","NCIT:C34492"],"synonyms":[{"name":"cocaine addiction","type":"exact"}],"termid":"MONDO:0005186","xrefs":{"Monarch":{"xref_id":"0005186"}}}


id: PBO:0089851
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EKC/KEOPS complex subunit Pcc1","termid":"PBO:0089851"}


id: MONDO:0019307
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Generalized non-Herlitz-type junctional epidermolysis bullosa is a form of non-Herlitz-type junctional epidermolysis bullosa (JEB-nH) characterized by generalized skin blistering, atrophic scarring, nail dystrophy or nail absence, and enamel hypoplasia, with extracutaneous involvement.","definition_xrefs":["Orphanet:79402"],"direct_ancestors":[{"relation_name":"is_a","term_name":"junctional epidermolysis bullosa, non-Herlitz type","termid":"MONDO:0009180"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"generalized junctional epidermolysis bullosa non-Herlitz type","secondary_identifiers":["SCTID:724225008","GARD:12922","UMLS:C0432326","MEDGEN:609458","DOID:0060738"],"synonyms":[{"name":"GABEB","type":"exact"},{"name":"JEB, generalised intermediate","type":"exact"},{"name":"JEB, generalized intermediate","type":"exact"},{"name":"JEB-nH gen","type":"exact"},{"name":"generalised atrophic benign epidermolysis bullosa","type":"exact"},{"name":"generalised junctional epidermolysis bullosa, non-Herlitz type","type":"exact"},{"name":"generalized atrophic benign epidermolysis bullosa","type":"exact"},{"name":"generalized junctional epidermolysis bullosa, non-Herlitz type","type":"exact"},{"name":"junctional epidermolysis bullosa generalisata mitis","type":"exact"},{"name":"junctional epidermolysis bullosa non-Herlitz type","type":"related"},{"name":"junctional epidermolysis bullosa, Disentis type","type":"exact"},{"name":"junctional epidermolysis bullosa, generalised intermediate","type":"related"},{"name":"junctional epidermolysis bullosa, generalized intermediate","type":"related"}],"termid":"MONDO:0019307","xrefs":{"Monarch":{"xref_id":"0019307"}}}


id: PBO:0108969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliary microtubule inner protein 2A","termid":"PBO:0108969"}


id: GO:2000077
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.","definition_xrefs":["GOC:obol","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell development","termid":"GO:0010721"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"is_a","term_name":"regulation of type B pancreatic cell development","termid":"GO:2000074"},{"relation_name":"negatively_regulates","term_name":"type B pancreatic cell development","termid":"GO:0003323"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of type B pancreatic cell development","synonyms":[{"name":"negative regulation of pancreatic B cell development","type":"exact"},{"name":"negative regulation of pancreatic beta cell development","type":"exact"}],"termid":"GO:2000077"}


id: PBO:0059834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial fission process 1","termid":"PBO:0059834"}


id: GO:0047044
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.","definition_xrefs":["RHEA:22400"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0033764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity","secondary_identifiers":["EC:1.1.1.53","MetaCyc:1.1.1.53-RXN"],"synonyms":[{"name":"(R)-20-hydroxysteroid dehydrogenase activity","type":"related"},{"name":"20beta-HSD","type":"related"},{"name":"20beta-hydroxysteroid dehydrogenase activity","type":"related"},{"name":"3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity","type":"broad"},{"name":"3alpha(or 20beta)-hydroxysteroid dehydrogenase activity","type":"broad"},{"name":"3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity","type":"broad"},{"name":"3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity","type":"broad"},{"name":"NADH-20beta-hydroxysteroid dehydrogenase activity","type":"broad"},{"name":"cortisone reductase activity","type":"related"},{"name":"dehydrogenase, 20beta-hydroxy steroid","type":"broad"},{"name":"delta4-3-ketosteroid hydrogenase activity","type":"broad"}],"termid":"GO:0047044"}


id: GO:0060334
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine-mediated signaling pathway","termid":"GO:0001959"},{"relation_name":"is_a","term_name":"regulation of response to type II interferon","termid":"GO:0060330"},{"relation_name":"regulates","term_name":"type II interferon-mediated signaling pathway","termid":"GO:0060333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of type II interferon-mediated signaling pathway","synonyms":[{"name":"regulation of gamma-interferon-mediated signaling pathway","type":"related"},{"name":"regulation of immune interferon signaling pathway","type":"exact"},{"name":"regulation of interferon-gamma-mediated signaling pathway","type":"exact"},{"name":"regulation of interferon-gamma-mediated signalling pathway","type":"exact"},{"name":"regulation of type II IFN-mediated signaling pathway","type":"broad"}],"termid":"GO:0060334"}


id: MONDO:0022519
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autoimmune myocarditis is an autoimmune disease that affects the heart. The condition is characterized by inflammation of the heart muscle (myocardium). Some people with autoimmune myocarditis have no noticeable symptoms of the condition. When present, signs and symptoms may include chest pain, abnormal heartbeat, shortness of breath, fatigue, signs of infection (i.e. fever, headache, sore throat, diarrhea), and leg swelling. The exact underlying cause of the condition is currently unknown; however, autoimmune conditions, in general, occur when the immune system mistakenly attacks healthy tissue. Treatment is based on the signs and symptoms present in each person. In some cases, medications that suppress the immune system may be recommended.","definition_xrefs":["GARD:0009519"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myocarditis","termid":"MONDO:0004496"},{"relation_name":"is_a","term_name":"autoimmune cardiomyopathy","termid":"MONDO:0030701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005267"],"is_obsolete":false,"name":"autoimmune myocarditis","secondary_identifiers":["GARD:9519","DOID:0080767","MEDGEN:299070","UMLS:C1608389"],"termid":"MONDO:0022519","xrefs":{"Monarch":{"xref_id":"0022519"}}}


id: GO:0106161
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of small RNA loading onto RISC.","definition_xrefs":["PMID:29775584","GOC:ha"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of small RNA loading onto RISC (obsolete GO:0106161)","termid":"GO:0106161"}


id: PBO:0090652
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCR4-Not complex NOT box subunit 3/5","termid":"PBO:0090652"}


id: GO:1990009
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any apoptotic process in a retinal cell.","definition_xrefs":["PMID:15558487","GOC:mtg_apoptosis","PMID:24664675"],"direct_ancestors":[{"relation_name":"is_a","term_name":"apoptotic process","termid":"GO:0006915"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"retinal cell apoptotic process","secondary_identifiers":["GO:0046674"],"synonyms":[{"name":"induction of retinal programmed cell death","type":"related"}],"termid":"GO:1990009"}


id: GO:0010029
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of seed germination.","definition_xrefs":["GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of seedling development","termid":"GO:1900140"},{"relation_name":"regulates","term_name":"seed germination","termid":"GO:0009845"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of seed germination","termid":"GO:0010029"}


id: MOD:01497
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ4plex-115 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iTRAQ4plex-115 reporter+balance reagent acylated residue","termid":"MOD:01492"},{"relation_name":"is_a","term_name":"iTRAQ4plex reporter+balance reagent O-acylated residue","termid":"MOD:01713"},{"relation_name":"is_a","term_name":"O3-acylated L-serine","termid":"MOD:02003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ4plex-115 reporter+balance reagent O3-acylated serine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"iTRAQ4plex115","type":"related"}],"termid":"MOD:01497"}


id: PBO:0050271
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosomal binding domain 3","termid":"PBO:0050271"}


id: MONDO:0005938
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infection of the kidney due to mycobacteria.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abdominal tuberculosis","termid":"MONDO:0000369"},{"relation_name":"is_a","term_name":"kidney disorder","termid":"MONDO:0005240"},{"relation_name":"is_a","term_name":"bacterial urinary tract infection","termid":"MONDO:0005247"},{"relation_name":"is_a","term_name":"urogenital tuberculosis","termid":"MONDO:0006002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"renal tuberculosis","secondary_identifiers":["DOID:9733","UMLS:C0041328","NCIT:C123020","MESH:D014398","MEDGEN:21728","EFO:0007463","ICD9:016.0","SCTID:44323002","ICD9:016.00"],"synonyms":[{"name":"kidney tuberculosis","type":"exact"},{"name":"tuberculosis of kidney","type":"exact"}],"termid":"MONDO:0005938","xrefs":{"Monarch":{"xref_id":"0005938"}}}


id: PBO:0078043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 33","termid":"PBO:0078043"}


id: PBO:0029796
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_rate_of_actin_cable_retrograde_transport","termid":"PBO:0029796"}


id: FYPO:0000378
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which apoptosis is normal (i.e. indistinguishable from wild type). Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies.","definition_xrefs":["GO:0006915","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process during vegetative growth","termid":"FYPO:0001319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001312","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal apoptosis","synonyms":[{"name":"apoptosis: normal","type":"related"}],"termid":"FYPO:0000378"}


id: PBO:0056678
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myocyte enhancer factor 2C","termid":"PBO:0056678"}


id: PBO:0045619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"double homeobox 4 like 31 (pseudogene)","termid":"PBO:0045619"}


id: PBO:0041662
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium voltage-gated channel auxiliary subunit gamma 7","termid":"PBO:0041662"}


id: PBO:0045426
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"divergent-paired related homeobox pseudogene 6","termid":"PBO:0045426"}


id: MONDO:0035475
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare primary lymphedema characterized by a highly variable lymphatic phenotype ranging from severe lymphatic-related hydrops fetalis, which may cause perinatal demise or fully resolve to become completely asymptomatic, to a mild presentation in older patients with persistent varicose veins, peripheral edema, and impaired lymph drainage in the lower limbs. Atrial septal defect has been described in association and may be the only anomaly in some patients.","definition_xrefs":["Orphanet:568065"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary lymphedema","termid":"MONDO:0019175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"EPHB4-related lymphatic-related hydrops fetalis","secondary_identifiers":["GARD:22302","MEDGEN:1802765","UMLS:C5680140"],"synonyms":[{"name":"EPHB4-related LRHF/GLD","type":"exact"},{"name":"EPHB4-related generalised lymphatic dysplasia with atrial septal defect","type":"exact"},{"name":"EPHB4-related generalised lymphatic dysplasia with non-immune hydrops fetalis","type":"exact"},{"name":"EPHB4-related generalized lymphatic dysplasia with atrial septal defect","type":"exact"},{"name":"EPHB4-related generalized lymphatic dysplasia with non-immune hydrops fetalis","type":"exact"}],"termid":"MONDO:0035475","xrefs":{"Monarch":{"xref_id":"0035475"}}}


id: GO:0140274
data:
  {"annotated_genes":["SJAG_04140","SJAG_00082","SJAG_01805","SJAG_01224","SJAG_03048","SJAG_01837"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[97827],"is_not":false,"summary":null,"term":"GO:0140274"},{"annotations":[89205,115812,110345,93001,101565],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140429"},{"annotations":[115815],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904967"},{"annotations":[115816],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140273"}]},"cv_name":"biological_process","definition":"The cell cycle process where kinetochore microtubule attachment defects are corrected.","definition_xrefs":["PMID:15525536"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle process","termid":"GO:0022402"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_01224":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_03048":null,"SJAG_04140":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"repair of kinetochore microtubule attachment defect","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"correction of kinetochore microtubule attachment defects","type":"exact"},{"name":"repair of kinetochore microtubule attachment defects","type":"exact"}],"termid":"GO:0140274","terms_by_termid":{"GO:0140273":null,"GO:0140274":null,"GO:0140429":null,"GO:1904967":null}}


id: GO:0099403
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.","definition_xrefs":["GOC:rph","GOC:BHF_telomere","GOC:BHF","PMID:26373281","GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maintenance of mitotic sister chromatid cohesion","termid":"GO:0034088"},{"relation_name":"part_of","term_name":"mitotic sister chromatid cohesion, telomeric","termid":"GO:0099404"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"maintenance of mitotic sister chromatid cohesion, telomeric","synonyms":[{"name":"maintenance of mitotic sister chromatin cohesion at telomere","type":"exact"},{"name":"maintenance of sister chromatin cohesion at telomere at mitosis","type":"exact"},{"name":"maintenance of telomeric mitotic sister chromatin cohesion","type":"exact"}],"termid":"GO:0099403"}


id: MONDO:0000961
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare benign adipose tissue neoplasm located within the lumen of a bronchus. It is predominantly found in males and usually originates within the fatty tissue between bronchial cartilage. May cause irreversible pulmonary damage distally. Two-thirds of the tumors occur on the right side and most are located on the first three subdivisions of the tracheobronchial tree.","definition_xrefs":["NCIT:C5063"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"lung benign neoplasm","termid":"MONDO:0002732"},{"relation_name":"is_a","term_name":"respiratory system benign neoplasm","termid":"MONDO:0000382"},{"relation_name":"is_a","term_name":"bronchial neoplasm","termid":"MONDO:0002807"},{"relation_name":"is_a","term_name":"lipoma","termid":"MONDO:0005106"},{"relation_name":"is_a","term_name":"benign soft tissue neoplasm","termid":"MONDO:0044335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endobronchial lipoma","secondary_identifiers":["MEDGEN:208874","UMLS:C0852937","DOID:10183"],"synonyms":[{"name":"endobronchial lipoma","type":"exact"}],"termid":"MONDO:0000961","xrefs":{"Monarch":{"xref_id":"0000961"}}}


id: PBO:0076665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T-box transcription factor T","termid":"PBO:0076665"}


id: PBO:0046012
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 1 pseudogene 7","termid":"PBO:0046012"}


id: MONDO:0016804
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete exercise intolerance with lactic acidosis (obsolete MONDO:0016804)","secondary_identifiers":["Orphanet:254843"],"termid":"MONDO:0016804","xrefs":{"Monarch":{"xref_id":"0016804"}}}


id: GO:0045251
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system.","definition_xrefs":["GOC:bhm","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005737"],"is_obsolete":false,"name":"electron transfer flavoprotein complex","synonyms":[{"name":"ETF complex","type":"exact"}],"termid":"GO:0045251"}


id: GO:0044109
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete cellular alcohol catabolic process (obsolete GO:0044109)","termid":"GO:0044109"}


id: MONDO:0019109
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"CANOMAD syndrome (Chronic Ataxic Neuropathy, Ophthalmoplegia, Monoclonal IgM protein, cold Agglutinins and Disialosyl antibodies) is a rare chronic immune-mediated demyelinating polyneuropathy.","definition_xrefs":["Orphanet:71279"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acquired peripheral neuropathy","termid":"MONDO:0015923"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"CANOMAD syndrome","secondary_identifiers":["MEDGEN:419872","GARD:9778","MESH:C537980","SCTID:715624006","UMLS:C2931684"],"synonyms":[{"name":"chronic ataxic neuropathy ophthalmoplegia M-protein agglutination disialosyl antibodies syndrome","type":"related"},{"name":"chronic ataxic neuropathy-ophthalmoplegia-IgM paraprotein-cold agglutinins-disialosyl antibodies syndrome","type":"exact"},{"name":"chronic sensory ataxic neuropathy with anti-disialosyl antibodies","type":"related"},{"name":"chronic sensory ataxic neuropathy with anti-dyalosyl IgM antibodies","type":"exact"}],"termid":"MONDO:0019109","xrefs":{"Monarch":{"xref_id":"0019109"}}}


id: PBO:0061403
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NPR2 like, GATOR1 complex subunit","termid":"PBO:0061403"}


id: MONDO:0006907
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, small, papular or nodular skin neoplasm that usually arises above the upper lip. It is characterized by an epithelial proliferation with a central cavity. The cavity wall is lined with keratinocytes.","definition_xrefs":["NCIT:C4468"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acanthoma","termid":"MONDO:0002093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"pilar sheath acanthoma","secondary_identifiers":["DOID:4322","icd11.foundation:281473034","MEDGEN:83398","SCTID:254693008","UMLS:C0346005"],"synonyms":[{"name":"Infundibuloisthmicoma","type":"exact"},{"name":"Pilar sheath acanthoma","type":"exact"},{"name":"acanthoma of Pilar sheath","type":"exact"},{"name":"acanthoma of the Pilar sheath","type":"exact"}],"termid":"MONDO:0006907","xrefs":{"Monarch":{"xref_id":"0006907"}}}


id: GO:0002221
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by a ligand binding to a pattern recognition receptor (PRR), and ending with the regulation of a downstream cellular process, e.g. transcription. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.","definition_xrefs":["PMID:15199967","GOC:add","GOC:ar","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"innate immune response-activating signaling pathway","termid":"GO:0002758"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"pattern recognition receptor signaling pathway","synonyms":[{"name":"PRR signaling pathway","type":"exact"},{"name":"pathogen receptor signaling pathway","type":"exact"},{"name":"pathogen receptor signalling pathway","type":"exact"}],"termid":"GO:0002221"}


id: PBO:0017873
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transporter for GlyceroPhosphodiester","termid":"PBO:0017873"}


id: GO:0003014
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).","definition_xrefs":["GOC:cjm","GOC:mtg_kidney_jan10","GOC:mtg_cardio"],"direct_ancestors":[{"relation_name":"is_a","term_name":"system process","termid":"GO:0003008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"renal system process","synonyms":[{"name":"excretory system process","type":"exact"},{"name":"kidney system process","type":"related"}],"termid":"GO:0003014"}


id: FYPO:0004673
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, contains more than one septum, and contains a nucleus that is broken into small fragments.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable elongated multinucleate vegetative cell","termid":"FYPO:0001493"},{"relation_name":"is_a","term_name":"fragmented nucleus","termid":"FYPO:0006661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0002403"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"output_of","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000631","FYPO:0002403","FYPO:0000002","FYPO:0000032","FYPO:0000004","FYPO:0000005","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"inviable elongated multiseptate vegetative cell with fragmented nucleus","synonyms":[{"name":"elongated inviable multiseptate cell with fragmented nucleus","type":"exact"},{"name":"inviable elongated multiseptate cell with fragmented nucleus during vegetative growth","type":"exact"},{"name":"inviable elongated multiseptate vegetative cell with fragmented DNA","type":"related"},{"name":"inviable elongated multiseptate vegetative cell with fragmented nucleus during mitotic cell cycle","type":"related"},{"name":"lethal; elongated multiseptate vegetative cell with fragmented nucleus","type":"exact"}],"termid":"FYPO:0004673"}


id: GO:0090724
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The center of the migrating motile tip of a growing nerve cell axon or dendrite.","definition_xrefs":["PMID:16260607","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"growth cone","termid":"GO:0030426"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"central region of growth cone","termid":"GO:0090724"}


id: GO:0016561
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation.","definition_xrefs":["PMID:11687502"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein transmembrane transport","termid":"GO:0065002"},{"relation_name":"part_of","term_name":"protein import into peroxisome matrix","termid":"GO:0016558"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"part_of","termid":"GO:0007031"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810","GO:0055085","GO:0007031"],"is_obsolete":false,"name":"protein import into peroxisome matrix, translocation","synonyms":[{"name":"peroxisome matrix protein import, translocation","type":"exact"},{"name":"peroxisome receptor translocation","type":"related"},{"name":"protein translocation during peroxisome matrix protein import","type":"exact"},{"name":"protein translocation during protein import into peroxisome matrix","type":"exact"},{"name":"protein translocation during protein transport into peroxisome matrix","type":"exact"},{"name":"protein transport into peroxisome matrix, translocation","type":"exact"}],"termid":"GO:0016561"}


id: GO:0070711
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.","definition_xrefs":["GOC:cb","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA dinucleotide insertion","termid":"GO:0070707"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"RNA adenosine-uridine insertion","synonyms":[{"name":"RNA AU insertion","type":"exact"}],"termid":"GO:0070711"}


id: PBO:0030205
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_elongated_multinucleate_vegetative_cell","termid":"PBO:0030205"}


id: GO:0075131
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete induction by symbiont of host protein kinase-mediated signal transduction (obsolete GO:0075131)","termid":"GO:0075131"}


id: GO:0099055
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.","definition_xrefs":["GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete integral component of postsynaptic membrane (obsolete GO:0099055)","termid":"GO:0099055"}


id: PBO:0064606
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POU class 3 homeobox 4","termid":"PBO:0064606"}


id: MONDO:0005827
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare syndrome characterized by almost complete absence of body fat, accentuated muscularity, insulin-resistant diabetes, hyperlipidemia, hepatomegaly, and hypermetabolism.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"type 2 diabetes mellitus","termid":"MONDO:0005148"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005015"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004335","MONDO:0005015"],"is_obsolete":false,"name":"lipoatrophic diabetes","secondary_identifiers":["NCIT:C34537","MEDGEN:4256","MESH:D003923","NANDO:2200465","SCTID:127012008","DOID:11712","EFO:0007346","UMLS:C0011859","SCTID:71325002"],"synonyms":[{"name":"diabete, lipoatrophic","type":"exact"},{"name":"diabetes, lipoatrophic","type":"related"},{"name":"lipoatrophic diabete","type":"related"},{"name":"lipoatrophic diabetes","type":"exact"},{"name":"lipoatrophic diabetes mellitus","type":"related"}],"termid":"MONDO:0005827","xrefs":{"Monarch":{"xref_id":"0005827"}}}


id: PBO:0070614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7a pseudogene 82","termid":"PBO:0070614"}


id: GO:0034396
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of transcription from RNA polymerase II promoter in response to iron (obsolete GO:0034396)","synonyms":[{"name":"down regulation of transcription from RNA polymerase II promoter in response to iron","type":"exact"},{"name":"down-regulation of transcription from RNA polymerase II promoter in response to iron","type":"exact"},{"name":"downregulation of transcription from RNA polymerase II promoter in response to iron","type":"exact"},{"name":"inhibition of transcription from RNA polymerase II promoter in response to iron","type":"narrow"},{"name":"negative regulation of transcription from Pol II promoter in response to iron","type":"exact"}],"termid":"GO:0034396"}


id: PBO:0057159
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 302d","termid":"PBO:0057159"}


id: GO:0043186
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes.","definition_xrefs":["PMID:11262230","GOC:dph","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic ribonucleoprotein granule","termid":"GO:0036464"},{"relation_name":"part_of","term_name":"germ plasm","termid":"GO:0060293"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005737"],"is_obsolete":false,"name":"P granule","secondary_identifiers":["GO:0018994"],"synonyms":[{"name":"germline granule","type":"broad"},{"name":"nuage","type":"narrow"},{"name":"polar granule","type":"narrow"}],"termid":"GO:0043186"}


id: GO:0015733
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transport","termid":"GO:0015718"},{"relation_name":"is_a","term_name":"organic hydroxy compound transport","termid":"GO:0015850"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transport","termid":"GO:1905039"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150","GO:0055085"],"is_obsolete":false,"name":"shikimate transmembrane transport","synonyms":[{"name":"shikimate transport","type":"related"}],"termid":"GO:0015733"}


id: GO:1902366
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.","definition_xrefs":["GOC:dph","GOC:TermGenie","PMID:21795391"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of Notch signaling pathway","termid":"GO:0008593"},{"relation_name":"regulates","term_name":"Notch signaling pathway involved in somitogenesis","termid":"GO:1902359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of Notch signaling pathway involved in somitogenesis","synonyms":[{"name":"regulation of N signaling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of N signaling pathway involved in somitogenesis","type":"exact"},{"name":"regulation of N signalling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of N signalling pathway involved in somitogenesis","type":"exact"},{"name":"regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of Notch receptor signaling pathway involved in somitogenesis","type":"exact"},{"name":"regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of Notch receptor signalling pathway involved in somitogenesis","type":"exact"},{"name":"regulation of Notch signaling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of Notch signalling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of Notch signalling pathway involved in somitogenesis","type":"exact"},{"name":"regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of Notch-receptor signaling pathway involved in somitogenesis","type":"exact"},{"name":"regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters","type":"exact"},{"name":"regulation of Notch-receptor signalling pathway involved in somitogenesis","type":"exact"}],"termid":"GO:1902366"}


id: GO:0102069
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD = zerumbone + NADH + H+.","definition_xrefs":["EC:1.1.1.326","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"zerumbone synthase activity","secondary_identifiers":["MetaCyc:RXN-10629","RHEA:32327"],"termid":"GO:0102069"}


id: PR:Q9HGL0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC800.12c gene.","definition_xrefs":["UniProtKB:Q9HGL0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized ubiquitin-like protein C800.12c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC800.12c","synonyms":[{"name":"Spom972h-SPBC800.12c","type":"exact"}],"termid":"PR:Q9HGL0"}


id: PBO:0069043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 288, pseudogene","termid":"PBO:0069043"}


id: PBO:0116295
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcriptional repressor, activator; role in adjustment to osmotic stress including modulation of mating efficiency; involved in repression of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, ergosterol biosynthetic genes in response to hyperosmotic stress; contributes to recruitment of Tup1p-Cyc8p general repressor to promoters; relocalizes to cytosol under hypoxia; ethanol stress increases the frequency of [MOT3+] formation, while hypoxia eliminates [MOT3+]","termid":"PBO:0116295"}


id: MONDO:0021127
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An characteristic of a disease in which the disease is not manifested as an isolated feature but has multiple distinct features.","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic or isolated","termid":"MONDO:0021126"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has a syndromic presentation","termid":"MONDO:0021127","xrefs":{"Monarch":{"xref_id":"0021127"}}}


id: PBO:0004131
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pal1 family protein","termid":"PBO:0004131"}


id: PBO:0069236
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 491, pseudogene","termid":"PBO:0069236"}


id: MONDO:0011438
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dermatitis","termid":"MONDO:0002406"},{"relation_name":"is_a","term_name":"sebaceous gland disorder","termid":"MONDO:0006607"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"acne","secondary_identifiers":["MTH:217","UMLS:C0702166","EFO:0003894","icd11.foundation:1892393023","ICD9:706.0","DOID:6543","NCIT:C27195","MEDGEN:152379","HP:0001061"],"synonyms":[{"name":"acne","type":"exact"},{"name":"acne (disease)","type":"exact"},{"name":"acne varioliformis","type":"exact"},{"name":"acne vulgaris","type":"exact"},{"name":"acne, adult","type":"narrow"},{"name":"frontalis acne","type":"exact"}],"termid":"MONDO:0011438","xrefs":{"Monarch":{"xref_id":"0011438"}}}


id: MOD:00214
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-serine residue to the polymer dermatan 4-sulfate by a D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl tetrasaccharide.","definition_xrefs":["PubMed:2914936","PubMed:3472204","RESID:AA0209"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-glycosyl-L-serine","termid":"MOD:00002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine","synonyms":[{"name":"beta-heparin","type":"exact"},{"name":"chondroitin sulfate B","type":"exact"},{"name":"dermatan 4-sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine","type":"exact"},{"name":"poly[beta-1,4-L-idopyranuronosyl-alpha-1,3-(2-acetamido-2-deoxy-4-sulfate D-galactosyl)]-beta-1,4-D-glucopyranuronosyl-beta-1,3-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-D-xylosyl-beta-1,3-L-serine","type":"exact"}],"termid":"MOD:00214"}


id: PBO:0091936
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIDdle","termid":"PBO:0091936"}


id: GO:0045682
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of epidermis development.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of developmental process","termid":"GO:0050793"},{"relation_name":"regulates","term_name":"epidermis development","termid":"GO:0008544"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of epidermis development","synonyms":[{"name":"regulation of epidermal development","type":"exact"},{"name":"regulation of hypodermis development","type":"related"}],"termid":"GO:0045682"}


id: MONDO:0020727
data:
  {"annotated_genes":["SJAG_02564"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86106],"is_not":false,"summary":null,"term":"MONDO:0020727"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial proton-transporting ATP synthase complex deficiency","termid":"MONDO:0014471"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02564":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"combined oxidative phosphorylation deficiency 22","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:616045","UMLS:C4015062","DOID:0111498","MEDGEN:863499"],"synonyms":[{"name":"COXPD22","type":"related"},{"name":"combined oxidative phosphorylation deficiency 22","type":"exact"},{"name":"combined oxidative phosphorylation deficiency type 22","type":"related"}],"termid":"MONDO:0020727","terms_by_termid":{"MONDO:0020727":null},"xrefs":{"Monarch":{"xref_id":"0020727"}}}


id: MONDO:0800147
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any genetic hemophagocytic lymphohistiocytosis in which the cause of the disease is an autosomal recessive variation in the RHOG gene.","definition_xrefs":["PMID:33513601"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary hemophagocytic lymphohistiocytosis","termid":"MONDO:0015541"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"hemophagocytic lymphohistiocytosis due to RhoG deficiency","termid":"MONDO:0800147","xrefs":{"Monarch":{"xref_id":"0800147"}}}


id: PBO:0031349
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_high_osmolarity","termid":"PBO:0031349"}


id: GO:0061256
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesonephric glomerular epithelial cell differentiation","termid":"GO:0061250"},{"relation_name":"is_a","term_name":"podocyte differentiation","termid":"GO:0072112"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric podocyte differentiation","synonyms":[{"name":"mesonephric glomerular visceral epithelial cell differentiation","type":"exact"}],"termid":"GO:0061256"}


id: PR:Q9P7X6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA replication complex GINS protein PSF1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR12914:SF2","OMA:SCHPO03092"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication complex GINS protein psf1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBP23A10.09","secondary_identifiers":["UniProtKB:Q9P7X6"],"synonyms":[{"name":"Spom972h-GINS1","type":"exact"}],"termid":"PR:Q9P7X6"}


id: PBO:0079459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trans-golgi network vesicle protein 23 homolog A","termid":"PBO:0079459"}


id: PBO:0057409
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 548k","termid":"PBO:0057409"}


id: MOD:00409
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a residue amino group with a formamido group.","definition_xrefs":["OMSSA:82","OMSSA:44"],"direct_ancestors":[{"relation_name":"is_a","term_name":"formylated residue","termid":"MOD:00493"},{"relation_name":"is_a","term_name":"N-acylated residue","termid":"MOD:00670"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-formylated residue","synonyms":[{"name":"Formyl","type":"related"},{"name":"NFoRes","type":"exact"},{"name":"ntermformyl","type":"exact"},{"name":"ntermpepformyl","type":"exact"}],"termid":"MOD:00409"}


id: GO:1901115
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of erythromycin.","definition_xrefs":["GOC:yaf","UniPathway:UPA00240","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"macrolide biosynthetic process","termid":"GO:0033068"},{"relation_name":"is_a","term_name":"erythromycin metabolic process","termid":"GO:1901113"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"erythromycin biosynthetic process","synonyms":[{"name":"erythromycin anabolism","type":"exact"},{"name":"erythromycin biosynthesis","type":"exact"},{"name":"erythromycin formation","type":"exact"},{"name":"erythromycin synthesis","type":"exact"}],"termid":"GO:1901115"}


id: MONDO:0006057
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete thymic lymphoma (obsolete MONDO:0006057)","termid":"MONDO:0006057","xrefs":{"Monarch":{"xref_id":"0006057"}}}


id: GO:0061971
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.","definition_xrefs":["PMID:29852585"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bone morphogenesis","termid":"GO:0060349"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"replacement bone morphogenesis","termid":"GO:0061971"}


id: PBO:0034408
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-localizes_to_(obsolete_localizes_to)","termid":"PBO:0034408"}


id: PBO:0053914
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1209","termid":"PBO:0053914"}


id: MONDO:0013332
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brachydactyly, type A1, with short stature, scoliosis, microcephaly, ptosis, hearing loss, and intellectual disability","secondary_identifiers":["MEDGEN:462240","OMIM:613627","SCTID:719162001","UMLS:C3150890"],"synonyms":[{"name":"Tsukahara syndrome","type":"related"},{"name":"brachydactyly, type A1, with short stature, scoliosis, microcephaly, ptosis, hearing loss, and intellectual disability","type":"exact"},{"name":"brachydactyly, type A1, with short stature, scoliosis, microcephaly, ptosis, hearing loss, and mental retardation","type":"exact"}],"termid":"MONDO:0013332","xrefs":{"Monarch":{"xref_id":"0013332"}}}


id: GO:0120532
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate) on specific serine residues of a core protein, on to which dermatan sulfate, chondroitin sulfate, heparan sulfate or heparin glycosaminoglycans may be assembled to synthesise the corresponding proteoglycan.","definition_xrefs":["MetaCyc:PWY-6557"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteoglycan biosynthetic process","termid":"GO:0030166"},{"relation_name":"part_of","term_name":"heparan sulfate proteoglycan biosynthetic process","termid":"GO:0015012"},{"relation_name":"part_of","term_name":"chondroitin sulfate proteoglycan biosynthetic process","termid":"GO:0050650"},{"relation_name":"part_of","term_name":"dermatan sulfate proteoglycan biosynthetic process","termid":"GO:0050651"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006790"],"is_obsolete":false,"name":"glycosaminoglycan-protein linkage region biosynthetic process","synonyms":[{"name":"Glycosaminoglycan biosynthesis, linkage tetrasaccharide","type":"exact"},{"name":"glycosaminoglycan-protein linkage region biosynthesis","type":"exact"}],"termid":"GO:0120532"}


id: PBO:0085308
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Phosphatase with a broad substrate specificity; has some similarity to GPM1/YKL152C, a phosphoglycerate mutase; YOR283W is not an essential gene","termid":"PBO:0085308"}


id: FYPO:0006218
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium ion starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitive to stress during vegetative growth","termid":"FYPO:0000304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0005447","FYPO:0001985","FYPO:0000139"],"is_obsolete":false,"name":"sensitive to potassium ion starvation","synonyms":[{"name":"decreased growth during cellular response to potassium ion starvation","type":"exact"},{"name":"decreased vegetative cell population growth during cellular response to potassium ion starvation","type":"exact"},{"name":"hypersensitive to potassium ion starvation","type":"exact"},{"name":"reduced growth in low potassium","type":"related"},{"name":"sensitive to potassium ion depletion","type":"exact"},{"name":"sensitive to potassium ion deprivation","type":"exact"},{"name":"sensitive to potassium ion starvation during mitotic cell cycle","type":"related"},{"name":"sensitive to potassium ion starvation during vegetative growth","type":"exact"},{"name":"sensitive to potassium starvation","type":"exact"}],"termid":"FYPO:0006218"}


id: GO:0004936
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors.","definition_xrefs":["IUPHAR_GPCR:1274","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adrenergic receptor activity","termid":"GO:0004935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"alpha-adrenergic receptor activity","synonyms":[{"name":"alpha adrenoceptor","type":"exact"}],"termid":"GO:0004936"}


id: GO:0102941
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 3,5-dihydroxyanisole O-methyltransferase activity (obsolete GO:0102941)","termid":"GO:0102941"}


id: PBO:0075262
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 18 pseudogene 15","termid":"PBO:0075262"}


id: GO:1903243
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.","definition_xrefs":["GOC:TermGenie","GOC:rl","GO_REF:0000058","GOC:BHF","PMID:19287093"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cardiac muscle hypertrophy","termid":"GO:0010614"},{"relation_name":"is_a","term_name":"negative regulation of cardiac muscle adaptation","termid":"GO:0010616"},{"relation_name":"is_a","term_name":"regulation of cardiac muscle hypertrophy in response to stress","termid":"GO:1903242"},{"relation_name":"negatively_regulates","term_name":"cardiac muscle hypertrophy in response to stress","termid":"GO:0014898"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cardiac muscle hypertrophy in response to stress","synonyms":[{"name":"down regulation of cardiac muscle hypertrophy in response to stress","type":"exact"},{"name":"down-regulation of cardiac muscle hypertrophy in response to stress","type":"exact"},{"name":"downregulation of cardiac muscle hypertrophy in response to stress","type":"exact"},{"name":"inhibition of cardiac muscle hypertrophy in response to stress","type":"narrow"}],"termid":"GO:1903243"}


id: PBO:0004543
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit Pmc4","termid":"PBO:0004543"}


id: RO:0001001
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"derives_into","termid":"RO:0001001"}


id: GO:0033023
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.","definition_xrefs":["GOC:add","PMID:11292031"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte homeostasis","termid":"GO:0001776"},{"relation_name":"is_a","term_name":"myeloid cell homeostasis","termid":"GO:0002262"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mast cell homeostasis","termid":"GO:0033023"}


id: GO:1990830
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.","definition_xrefs":["PMID:12801913"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to cytokine stimulus","termid":"GO:0071345"},{"relation_name":"is_a","term_name":"response to leukemia inhibitory factor","termid":"GO:1990823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to leukemia inhibitory factor","synonyms":[{"name":"cellular response to CDF","type":"exact"},{"name":"cellular response to cholinergic differentiation factor","type":"exact"}],"termid":"GO:1990830"}


id: PBO:0042370
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD180 molecule","termid":"PBO:0042370"}


id: MONDO:0009126
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Duodenal atresia is an embryopathy of the cranial intestine that leads to a complete absence of the duodenal lumen.","definition_xrefs":["Orphanet:1203"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal atresia","termid":"MONDO:0001045"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"duodenal atresia","secondary_identifiers":["HP:0002247","NCIT:C101025","MedDRA:10013812","MESH:C535720","NORD:1066","MEDGEN:75602","ICD9:751.1","SCTID:51118003","DOID:0080216","UMLS:C0266174","OMIM:223400","GARD:54"],"synonyms":[{"name":"Duodenal Atresia or Stenosis","type":"exact"},{"name":"atresia of duodenum","type":"exact"},{"name":"congenital atresia of duodenum","type":"exact"},{"name":"congenital duodenal atresia","type":"exact"},{"name":"duodenal atresia","type":"exact"},{"name":"duodenal atresia (disease)","type":"exact"},{"name":"duodenal stenosis","type":"related"}],"termid":"MONDO:0009126","xrefs":{"Monarch":{"xref_id":"0009126"}}}


id: GO:0006100
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete tricarboxylic acid cycle intermediate metabolic process (obsolete GO:0006100)","synonyms":[{"name":"Krebs cycle intermediate metabolic process","type":"exact"},{"name":"Krebs cycle intermediate metabolism","type":"exact"},{"name":"TCA intermediate metabolic process","type":"exact"},{"name":"TCA intermediate metabolism","type":"exact"},{"name":"citric acid cycle intermediate metabolic process","type":"exact"},{"name":"citric acid cycle intermediate metabolism","type":"exact"},{"name":"tricarboxylic acid cycle intermediate metabolic process","type":"exact"},{"name":"tricarboxylic acid cycle intermediate metabolism","type":"exact"}],"termid":"GO:0006100"}


id: PBO:0085374
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication","termid":"PBO:0085374"}


id: MONDO:0017631
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare tumor of gallbladder and extrahepatic biliary tract (obsolete MONDO:0017631)","secondary_identifiers":["Orphanet:306633"],"synonyms":[{"name":"rare tumor of gallbladder and EBT","type":"exact"}],"termid":"MONDO:0017631","xrefs":{"Monarch":{"xref_id":"0017631"}}}


id: PBO:0046188
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"engulfment and cell motility 2 pseudogene 1","termid":"PBO:0046188"}


id: PBO:0074942
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 107","termid":"PBO:0074942"}


id: GO:0050968
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of chemical stimulus involved in sensory perception","termid":"GO:0050907"},{"relation_name":"is_a","term_name":"detection of stimulus involved in sensory perception of pain","termid":"GO:0062149"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of chemical stimulus involved in sensory perception of pain","synonyms":[{"name":"chemical nociception","type":"related"},{"name":"perception of pain, detection of chemical stimulus","type":"exact"},{"name":"perception of pain, sensory detection of chemical stimulus","type":"exact"},{"name":"perception of pain, sensory transduction of chemical stimulus","type":"exact"},{"name":"sensory detection of chemical stimulus during perception of pain","type":"exact"},{"name":"sensory transduction of chemical stimulus during perception of pain","type":"exact"}],"termid":"GO:0050968"}


id: PBO:0059521
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L","termid":"PBO:0059521"}


id: GO:0090729
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.","definition_xrefs":["GOC:pt"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molecular_function","termid":"GO:0003674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674"],"is_obsolete":false,"name":"toxin activity","secondary_identifiers":["GO:0050827","Wikipedia:Toxin"],"synonyms":[{"name":"toxin receptor binding","type":"exact"}],"termid":"GO:0090729"}


id: GO:0042639
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The resting phase of hair cycle.","definition_xrefs":["PMID:12230507"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hair cycle phase","termid":"GO:0044851"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"telogen","synonyms":[{"name":"hair resting phase","type":"narrow"}],"termid":"GO:0042639"}


id: PBO:0000979
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calmodulin family","termid":"PBO:0000979"}


id: PBO:0111784
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zf-UBP type","termid":"PBO:0111784"}


id: PR:O13842
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cda1 gene.","definition_xrefs":["UniProtKB:O13842","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chitin deacetylase 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC19G12.03","synonyms":[{"name":"Spom972h-cda1","type":"exact"}],"termid":"PR:O13842"}


id: PBO:0091267
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cdc25 can modulate the probability of entering mitosis at a given cell size","termid":"PBO:0091267"}


id: GO:1902681
data:
  {"annotated_genes":["SJAG_03997"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[102403],"is_not":false,"summary":null,"term":"GO:1902681"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.","definition_xrefs":["GOC:TermGenie","PMID:23260662","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of chromosome organization","termid":"GO:0033044"},{"relation_name":"is_a","term_name":"regulation of DNA-templated DNA replication","termid":"GO:0090329"},{"relation_name":"regulates","term_name":"replication fork arrest at rDNA repeats","termid":"GO:0031582"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03997":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006260"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0006260"],"is_obsolete":false,"name":"regulation of replication fork arrest at rDNA repeats","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of replication fork arrest at ribosomal DNA repeats","type":"exact"},{"name":"regulation of replication fork blocking at rDNA repeats","type":"exact"}],"termid":"GO:1902681","terms_by_termid":{"GO:1902681":null}}


id: MONDO:0042968
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndrome caused by partial chromosomal duplication","termid":"MONDO:0000762"},{"relation_name":"is_a","term_name":"chromosome 12 disorder","termid":"MONDO:0700019"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial duplication of chromosome 12","termid":"MONDO:0042968","xrefs":{"Monarch":{"xref_id":"0042968"}}}


id: GO:0150074
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.","definition_xrefs":["GOC:bc","PMID:26670206","GOC:aruk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transferase activity","termid":"GO:0051347"},{"relation_name":"is_a","term_name":"regulation of protein-glutamine gamma-glutamyltransferase activity","termid":"GO:0150073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein-glutamine gamma-glutamyltransferase activity","termid":"GO:0150074"}


id: GO:0019191
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.","definition_xrefs":["GOC:mtg_transport","ISBN:0815340729","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disaccharide transmembrane transporter activity","termid":"GO:0015154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"cellobiose transmembrane transporter activity","secondary_identifiers":["GO:0019190"],"synonyms":[{"name":"cellobiose permease activity","type":"exact"}],"termid":"GO:0019191"}


id: MONDO:0018159
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"atypical hemolytic-uremic syndrome","termid":"MONDO:0016244"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"atypical hemolytic-uremic syndrome with DGKE deficiency","secondary_identifiers":["UMLS:C5679921","GARD:17543","DOID:0080388","Orphanet:357008","MEDGEN:1826167"],"synonyms":[{"name":"D-HUS with DGKE deficiency","type":"exact"},{"name":"aHUS with DGKE deficiency","type":"exact"},{"name":"atypical HUS with DGKE deficiency","type":"exact"},{"name":"hemolytic-uremic syndrome without diarrhea with DGKE deficiency","type":"exact"},{"name":"hemolytic-uremic syndrome without diarrhoea with DGKE deficiency","type":"exact"}],"termid":"MONDO:0018159","xrefs":{"Monarch":{"xref_id":"0018159"}}}


id: GO:0048399
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mesodermal cell fate specification","termid":"GO:0042661"},{"relation_name":"regulates","term_name":"intermediate mesodermal cell fate specification","termid":"GO:0048398"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of intermediate mesodermal cell fate specification","termid":"GO:0048399"}


id: GO:0001320
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.","definition_xrefs":["GOC:jh"],"gene_count":0,"genotype_count":0,"name":"obsolete age-dependent response to reactive oxygen species involved in chronological cell aging (obsolete GO:0001320)","synonyms":[{"name":"age-dependent response to AOS during chronological cell aging","type":"related"},{"name":"age-dependent response to ROI during chronological cell aging","type":"related"},{"name":"age-dependent response to ROS during chronological cell aging","type":"related"},{"name":"age-dependent response to active oxygen species during chronological cell aging","type":"related"},{"name":"age-dependent response to reactive oxidative species during chronological cell aging","type":"related"},{"name":"age-dependent response to reactive oxygen intermediate during chronological cell aging","type":"related"},{"name":"age-dependent response to reactive oxygen species during chronological cell ageing","type":"related"},{"name":"age-dependent response to reactive oxygen species during chronological cell aging","type":"related"}],"termid":"GO:0001320"}


id: GO:0001632
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate.","definition_xrefs":["ISBN:0198506732","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukotriene receptor activity","termid":"GO:0004974"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"leukotriene B4 receptor activity","synonyms":[{"name":"BLT receptor","type":"narrow"}],"termid":"GO:0001632"}


id: MONDO:0015289
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infectious epithelial keratitis is a rare, potentially sight-threatening, acquired ocular disease chracterized by corneal epithelium inflammation resulting from viral (mainly Herpes Simplex virus), bacterial, fungic or protist infection, manifesting with variable symptoms, such as conjunctival hyperemia, lacrimation, rapid onset of pain, blurred vision and/or photophobia, depending on the causative agent.","definition_xrefs":["Orphanet:137593"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"herpes simplex virus keratitis","termid":"MONDO:0015288"},{"relation_name":"is_a","term_name":"viral eye infection","termid":"MONDO:0020950"},{"relation_name":"is_a","term_name":"corneal infection","termid":"MONDO:0023865"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"infectious epithelial keratitis","secondary_identifiers":["icd11.foundation:2103923676","UMLS:C4749790","GARD:19877","MEDGEN:1660649"],"termid":"MONDO:0015289","xrefs":{"Monarch":{"xref_id":"0015289"}}}


id: PBO:0038291
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase feature property types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interaction_type","termid":"PBO:0038291"}


id: MONDO:0013431
data:
  {"annotated_genes":["SJAG_02607"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86123],"is_not":false,"summary":null,"term":"MONDO:0013431"}]},"cv_name":"mondo","definition":"Any Meier-Gorlin syndrome in which the cause of the disease is a mutation in the CDT1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Meier-Gorlin syndrome","termid":"MONDO:0016817"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02607":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Meier-Gorlin syndrome 4","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:462470","GARD:15711","OMIM:613804","UMLS:C3151120","DOID:0080515"],"synonyms":[{"name":"CDT1 Meier-Gorlin syndrome","type":"exact"},{"name":"MGORS4","type":"related"},{"name":"Meier-GORLIN syndrome 4","type":"related"},{"name":"Meier-Gorlin syndrome 4","type":"exact"},{"name":"Meier-Gorlin syndrome caused by mutation in CDT1","type":"exact"},{"name":"Meier-Gorlin syndrome type 4","type":"exact"}],"termid":"MONDO:0013431","terms_by_termid":{"MONDO:0013431":null},"xrefs":{"Monarch":{"xref_id":"0013431"}}}


id: PBO:0048603
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GID complex subunit 4 homolog","termid":"PBO:0048603"}


id: PBO:0017946
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Tam8","termid":"PBO:0017946"}


id: GO:0071455
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to increased oxygen levels","termid":"GO:0036295"},{"relation_name":"is_a","term_name":"response to hyperoxia","termid":"GO:0055093"},{"relation_name":"is_a","term_name":"cellular response to chemical stress","termid":"GO:0062197"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to hyperoxia","synonyms":[{"name":"cellular response to hyperoxic stress","type":"exact"},{"name":"cellular response to increased oxygen tension","type":"exact"}],"termid":"GO:0071455"}


id: GO:0033296
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to the D- or L-enantiomer of rhamnose.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monosaccharide binding","termid":"GO:0048029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"rhamnose binding","termid":"GO:0033296"}


id: PBO:0057105
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 196a-2","termid":"PBO:0057105"}


id: MONDO:0008170
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas.","definition_xrefs":["NCIT:C7431"],"direct_ancestors":[{"relation_name":"is_a","term_name":"female reproductive organ cancer","termid":"MONDO:0001416"},{"relation_name":"is_a","term_name":"ovarian neoplasm","termid":"MONDO:0021068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"ovarian cancer","secondary_identifiers":["ICD9:183.0","SCTID:363443007","MEDGEN:216027","icd11.foundation:685124533","DOID:2394","MESH:D010051","Orphanet:213500","UMLS:C1140680","OMIM:167000","GARD:7295"],"synonyms":[{"name":"cancer of ovary","type":"exact"},{"name":"cancer of the ovary","type":"exact"},{"name":"malignant neoplasm of ovary","type":"exact"},{"name":"malignant neoplasm of the ovary","type":"exact"},{"name":"malignant ovarian neoplasm","type":"exact"},{"name":"malignant ovarian tumor","type":"exact"},{"name":"malignant ovarian tumour","type":"exact"},{"name":"malignant ovary neoplasm","type":"exact"},{"name":"malignant tumor of ovary","type":"exact"},{"name":"malignant tumor of the ovary","type":"exact"},{"name":"malignant tumour of ovary","type":"exact"},{"name":"malignant tumour of the ovary","type":"exact"},{"name":"ovarian cancer","type":"exact"},{"name":"ovarian cancer, epithelial","type":"related"},{"name":"ovarian cancer, somatic","type":"exact"},{"name":"ovarian malignant tumor","type":"exact"},{"name":"ovarian malignant tumour","type":"exact"},{"name":"ovarian neoplasm","type":"broad"},{"name":"ovary cancer","type":"exact"},{"name":"ovary neoplasm","type":"broad"},{"name":"primary ovarian cancer","type":"related"},{"name":"tumor of the ovary","type":"broad"},{"name":"tumour of the ovary","type":"broad"}],"termid":"MONDO:0008170","xrefs":{"Monarch":{"xref_id":"0008170"}}}


id: MONDO:1011972
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteochondromatosis, non-human animal","secondary_identifiers":["OMIA:002555"],"termid":"MONDO:1011972","xrefs":{"Monarch":{"xref_id":"1011972"}}}


id: GO:0005071
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete transmembrane receptor protein serine/threonine kinase signaling protein activity (obsolete GO:0005071)","synonyms":[{"name":"transmembrane receptor protein serine/threonine kinase signaling protein activity","type":"exact"},{"name":"transmembrane receptor protein serine/threonine kinase signalling protein activity","type":"exact"}],"termid":"GO:0005071"}


id: PBO:0068016
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 321","termid":"PBO:0068016"}


id: MONDO:0008429
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Singleton-Merten dysplasia is characterized by dental dysplasia, progressive calcification of the thoracic aorta with stenosis, osteoporosis and expansion of the marrow cavities in hand bones. Additional features included generalized muscle weakness and atrophy, and chronic psoriasiform skin eruptions. It has been reported in four unrelated patients (male and female) and in a family with multiple affected members (male).","definition_xrefs":["Orphanet:85191"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with decreased bone density (obsolete MONDO:0019704)","termid":"MONDO:0019704"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"type 1 interferonopathy of childhood","termid":"MONDO:0957408"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Singleton-Merten dysplasia","secondary_identifiers":["UMLS:C0432254","MESH:C537343","SCTID:254114000","icd11.foundation:1084593684","MEDGEN:98481","NORD:1718","OMIMPS:182250","GARD:122","ICD9:733.29"],"synonyms":[{"name":"Merten-Singleton syndrome","type":"exact"},{"name":"SGMRT1","type":"related"},{"name":"SM syndrome","type":"related"},{"name":"Singleton Merten syndrome","type":"exact"},{"name":"Singleton-Merten syndrome","type":"exact"},{"name":"singleton Merten syndrome","type":"exact"},{"name":"syndrome of widened medullary cavities of the metacarpals and phalanges, aortic calcification and abnormal dentition","type":"related"},{"name":"widened medullary cavities of bone, aortic calcification, abnormal dentition, and muscular weakness","type":"related"}],"termid":"MONDO:0008429","xrefs":{"Monarch":{"xref_id":"0008429"}}}


id: GO:0039691
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.","definition_xrefs":["VZ:1936","GOC:jl","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral RNA genome replication","termid":"GO:0039694"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"double stranded viral RNA replication","termid":"GO:0039691"}


id: MONDO:0024454
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease that involves the sacral nerve plexus.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lumbosacral plexus lesion","termid":"MONDO:0001829"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"sacral nerve plexus disorder","secondary_identifiers":["UMLS:C2931445","MEDGEN:419804","MESH:C537224"],"synonyms":[{"name":"disease of sacral nerve plexus","type":"exact"},{"name":"disease or disorder of sacral nerve plexus","type":"exact"},{"name":"disorder of sacral nerve plexus","type":"exact"},{"name":"sacral nerve plexus disease or disorder","type":"exact"},{"name":"sacral nerve plexus disorder","type":"exact"},{"name":"sacral plexopathy","type":"exact"}],"termid":"MONDO:0024454","xrefs":{"Monarch":{"xref_id":"0024454"}}}


id: SO:0000956
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Structural unit composed of a self-replicating, single-stranded DNA molecule.","definition_xrefs":["SO:ma"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"single","termid":"SO:0000984"},{"relation_name":"is_a","term_name":"DNA_chromosome","termid":"SO:0000954"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"single_stranded_DNA_chromosome","synonyms":[{"name":"single stranded DNA chromosome","type":"exact"}],"termid":"SO:0000956"}


id: GO:0008343
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Feeding behavior in a fully developed and mature organism.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"feeding behavior","termid":"GO:0007631"},{"relation_name":"is_a","term_name":"adult behavior","termid":"GO:0030534"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"adult feeding behavior","synonyms":[{"name":"adult feeding behaviour","type":"exact"}],"termid":"GO:0008343"}


id: MONDO:0013994
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Joubert syndrome in which the cause of the disease is a mutation in the TMEM231 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Joubert syndrome with ocular defect","termid":"MONDO:0016364"},{"relation_name":"is_a","term_name":"Joubert syndrome","termid":"MONDO:0018772"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0020022","MONDO:0006025"],"is_obsolete":false,"name":"Joubert syndrome 20","secondary_identifiers":["OMIM:614970","MEDGEN:767149","DOID:0110989","GARD:15887","UMLS:C3554235"],"synonyms":[{"name":"JBTS20","type":"exact"},{"name":"Joubert syndrome 20","type":"exact"},{"name":"Joubert syndrome caused by mutation in TMEM231","type":"exact"},{"name":"Joubert syndrome type 20","type":"exact"},{"name":"TMEM231 Joubert syndrome","type":"exact"}],"termid":"MONDO:0013994","xrefs":{"Monarch":{"xref_id":"0013994"}}}


id: MONDO:0009356
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive form of humeroradial synostosis (disease).","definition_xrefs":["MONDO:patterns/autosomal_recessive"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"humeroradial synostosis","termid":"MONDO:0007737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005497"],"is_obsolete":false,"name":"autosomal recessive humeroradial synostosis","secondary_identifiers":["UMLS:C1856055","MEDGEN:343467","OMIM:236400"],"synonyms":[{"name":"autosomal recessive humeroradial synostosis (disease)","type":"exact"},{"name":"humeroradial synostosis","type":"related"},{"name":"humeroradial synostosis (disease), autosomal recessive","type":"exact"},{"name":"humeroradial/multiple synostosis syndrome","type":"related"}],"termid":"MONDO:0009356","xrefs":{"Monarch":{"xref_id":"0009356"}}}


id: MONDO:1011219
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Corneal dystrophy that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"corneal dystrophy, non-human animal","termid":"MONDO:1010320"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"corneal dystrophy, dog","secondary_identifiers":["OMIA:000230-9615"],"termid":"MONDO:1011219","xrefs":{"Monarch":{"xref_id":"1011219"}}}


id: PBO:0016998
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by S. cerevisiae CAT5","termid":"PBO:0016998"}


id: PR:O14087
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rim1 gene.","definition_xrefs":["UniProtKB:O14087","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"single-stranded DNA-binding protein rim1, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC2F3.04c","synonyms":[{"name":"Spom972h-rim1","type":"exact"},{"name":"mitochondrial ssDNA-binding protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14087"}


id: GO:0035756
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont moves from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:bf","PMID:10639460"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated migration across host tissue barrier","termid":"GO:0141142"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated migration across host transepithelium","synonyms":[{"name":"migration in host through an epithelial cell layer","type":"exact"},{"name":"migration of symbiont within host by transepithelial trafficking","type":"exact"},{"name":"symbiont-mediated migration through host transepithelium","type":"exact"},{"name":"transepithelial migration of symbiont in host","type":"exact"},{"name":"transmigration of symbiont in host","type":"related"}],"termid":"GO:0035756"}


id: FYPO:0001158
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative phenotype","termid":"FYPO:0001312"},{"relation_name":"is_a","term_name":"vegetative cell phenotype","termid":"FYPO:0001320"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal cellular pH","synonyms":[{"name":"normal cellular pH during mitotic cell cycle","type":"related"},{"name":"normal cellular pH during vegetative growth","type":"exact"},{"name":"normal cellular pH level","type":"exact"}],"termid":"FYPO:0001158"}


id: PBO:0087287
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress","termid":"PBO:0087287"}


id: GO:0009918
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol.","definition_xrefs":["ISBN:0943088399"],"gene_count":0,"genotype_count":0,"name":"obsolete sterol delta7 reductase activity (obsolete GO:0009918)","synonyms":[{"name":"sterol delta-7 reductase activity","type":"exact"}],"termid":"GO:0009918"}


id: PBO:0072288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S24 pseudogene 6","termid":"PBO:0072288"}


id: GO:0045658
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of neutrophil differentiation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of granulocyte differentiation","termid":"GO:0030852"},{"relation_name":"regulates","term_name":"neutrophil differentiation","termid":"GO:0030223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of neutrophil differentiation","termid":"GO:0045658"}


id: PBO:0071752
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein lateral stalk subunit P0","termid":"PBO:0071752"}


id: FYPO:0008096
data:
  {"alleles_by_uniquename":{"SJAG_00266:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00266","name":"atf1delta","uniquename":"SJAG_00266:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"},"SJAG_04312:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04312","name":"pka1delta","uniquename":"SJAG_04312:allele-1"},"SJAG_04332:allele-1":{"allele_type":"amino_acid_mutation","description":"I30T,T572P","gene_uniquename":"SJAG_04332","name":"cdc25-D9","uniquename":"SJAG_04332:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[118615,118677,118689],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0001122"},{"annotations":[118443],"is_not":false,"rel_names":["is_a","has_part"],"summary":null,"term":"FYPO:0007701"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell size phenotype in which a cell has a volume that is larger than normal.","definition_xrefs":["PMID:26566110"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell size","termid":"FYPO:0001127"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00266":null,"SJAG_02592":null,"SJAG_04312":null,"SJAG_04332":null},"genotype_count":4,"genotypes_by_uniquename":{"atf1delta":{"display_name":"atf1delta","display_uniquename":"atf1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00266:allele-1","expression":"Null"}]}]},"cdc25-D9-I30T,T572P-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"cdc25-D9(I30T,T572P aa)","display_uniquename":"cdc25-D9-I30T,T572P-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04332:allele-1","expression":"Not assayed or wild type"}]}]},"pka1delta":{"display_name":"pka1delta","display_uniquename":"pka1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04312:allele-1","expression":"Null"}]}]},"sty1delta":{"display_name":"sty1delta","display_uniquename":"sty1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02592:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000005","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased cell size","references_by_uniquename":{"PMID:25866389":null,"PMID:27678009":null,"PMID:31150379":null},"single_locus_annotated_genes":["SJAG_02592","SJAG_04312","SJAG_04332","SJAG_00266"],"single_locus_genotype_uniquenames":["pka1delta","sty1delta","cdc25-D9-I30T,T572P-amino_acid_mutation-expression-not_assayed_or_wild_type","atf1delta"],"termid":"FYPO:0008096","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000005":null,"FYECO:0000102":null,"FYECO:0000137":null,"FYPO:0001122":null,"FYPO:0007701":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000003":null}}


id: GO:0060785
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of apoptotic process","termid":"GO:0042981"},{"relation_name":"part_of","term_name":"homeostasis of number of cells within a tissue","termid":"GO:0048873"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of apoptosis involved in tissue homeostasis","termid":"GO:0060785"}


id: PBO:0028917
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_transcription_during_cellular_response_to_osmotic_stress","termid":"PBO:0028917"}


id: PBO:0001839
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycine decarboxylase T subunit (predicted)","termid":"PBO:0001839"}


id: MONDO:0002332
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease involving the spleen.","direct_ancestors":[{"relation_name":"is_a","term_name":"hematologic disorder","termid":"MONDO:0005570"},{"relation_name":"is_a","term_name":"lymphatic system disorder","termid":"MONDO:0005833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"splenic disorder","secondary_identifiers":["DOID:2529","UMLS:C0037997","NCIT:C35823","SCTID:51244008","MESH:D013158","MEDGEN:21291","ICD9:289.50","ICD10CM:D73","EFO:0009002"],"synonyms":[{"name":"Dyssplenism","type":"exact"},{"name":"disease of spleen","type":"exact"},{"name":"disease or disorder of spleen","type":"exact"},{"name":"disorder of spleen","type":"exact"},{"name":"spleen disease","type":"exact"},{"name":"spleen disease or disorder","type":"exact"},{"name":"spleen disorder","type":"exact"},{"name":"splenic disease","type":"exact"},{"name":"splenic disorder","type":"exact"}],"termid":"MONDO:0002332","xrefs":{"Monarch":{"xref_id":"0002332"}}}


id: GO:1905887
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing.","definition_xrefs":["GOC:TermGenie","PMID:15601708","GO_REF:0000069"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyol transmembrane transport","termid":"GO:0015791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0055085","GO:0051179"],"is_obsolete":false,"name":"autoinducer AI-2 transmembrane transport","synonyms":[{"name":"(2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol transmembrane transport","type":"exact"},{"name":"AI-2 transmembrane transport","type":"exact"},{"name":"autoinducer 2 transmembrane transport","type":"exact"}],"termid":"GO:1905887"}


id: PBO:0060064
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND5 pseudogene 11","termid":"PBO:0060064"}


id: PBO:0090169
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell surface protein involved in ascospore wall assembly, GPI anchored Meu10","termid":"PBO:0090169"}


id: GO:0043605
data:
  {"annotated_genes":["SJAG_04679","SJAG_02766","SJAG_00035","SJAG_05287"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90974,91660],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000256"},{"annotations":[118117,90654],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043419"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catabolic process","termid":"GO:0009056"},{"relation_name":"is_a","term_name":"amide metabolic process","termid":"GO:0043603"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00035":null,"SJAG_02766":null,"SJAG_04679":null,"SJAG_05287":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"amide catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"cellular amide catabolic process","type":"exact"}],"termid":"GO:0043605","terms_by_termid":{"GO:0000256":null,"GO:0043419":null}}


id: GO:1990891
data:
  {"annotated_genes":["SJAG_01837"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[115811],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1905824"}]},"cv_name":"biological_process","definition":"The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis.","definition_xrefs":["PMID:21633354"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitotic cell cycle process","termid":"GO:1903047"},{"relation_name":"part_of","term_name":"mitotic sister chromatid separation","termid":"GO:0051306"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01837":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0000070"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0000070"],"is_obsolete":false,"name":"mitotic sister chromatid arm separation","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1990891","terms_by_termid":{"GO:1905824":null}}


id: GO:0050699
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.","definition_xrefs":["PMID:14531730"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein domain specific binding","termid":"GO:0019904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"WW domain binding","termid":"GO:0050699"}


id: MONDO:0012620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"prostate cancer, hereditary","termid":"MONDO:0700275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"prostate cancer, hereditary, 10","secondary_identifiers":["MESH:C567011","OMIM:611100","UMLS:C1970192","MEDGEN:370202","GARD:15507"],"synonyms":[{"name":"HPC10","type":"exact"},{"name":"prostate cancer, hereditary, 10","type":"exact"}],"termid":"MONDO:0012620","xrefs":{"Monarch":{"xref_id":"0012620"}}}


id: GO:0018272
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.","definition_xrefs":["RESID:AA0119"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-lysine modification","termid":"GO:0018205"},{"relation_name":"is_a","term_name":"protein-pyridoxal-5-phosphate linkage","termid":"GO:0018352"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine","termid":"GO:0018272"}


id: MONDO:0700126
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A chromosomal disorder consisting of the presence of an extra chromosome 21.","definition_xrefs":["MONDO:patterns/trisomy","PMID:29218069"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Down syndrome","termid":"MONDO:0008608"},{"relation_name":"is_a","term_name":"trisomy","termid":"MONDO:0700065"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trisomy 21","secondary_identifiers":["MEDGEN:760825","UMLS:C3537167"],"termid":"MONDO:0700126","xrefs":{"Monarch":{"xref_id":"0700126"}}}


id: FYPO:0005211
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during anaphase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to mitotic spindle pole body during mitosis","termid":"FYPO:0002822"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"decreased protein localization to mitotic spindle pole body during anaphase","synonyms":[{"name":"decreased protein localisation to mitotic spindle pole body during anaphase","type":"exact"},{"name":"decreased protein localization to mitotic SPB during anaphase","type":"exact"},{"name":"decreased protein localization to mitotic spindle pole body during mitotic anaphase","type":"exact"},{"name":"decreased protein localization to spindle pole body during anaphase during vegetative growth","type":"exact"},{"name":"reduced protein localization to mitotic spindle pole body during anaphase","type":"exact"}],"termid":"FYPO:0005211"}


id: PR:O60167
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- yap18 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O60167"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ENTH domain-containing protein C19F8.03c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC19F8.03c","synonyms":[{"name":"Spom972h-yap18","type":"exact"}],"termid":"PR:O60167"}


id: PBO:0052965
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L1CAM antisense RNA 1","termid":"PBO:0052965"}


id: PBO:0067944
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 246","termid":"PBO:0067944"}


id: MONDO:0010951
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A dilated cardiomyopathy that has material basis in variation in the chromosome region 9q13.","definition_xrefs":["PMID:7573045","DOID:0110443"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"dilated cardiomyopathy 1B","secondary_identifiers":["MEDGEN:1814491","OMIM:600884","GARD:15323","UMLS:C5700078"],"synonyms":[{"name":"cardiomyopathy, dilated 1B","type":"exact"},{"name":"cardiomyopathy, dilated, 1B","type":"related"},{"name":"cardiomyopathy, familial dilated","type":"related"},{"name":"cardiomyopathy, familial dilated, 1","type":"related"},{"name":"dilated cardiomyopathy type 1B","type":"exact"}],"termid":"MONDO:0010951","xrefs":{"Monarch":{"xref_id":"0010951"}}}


id: MONDO:0035584
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare ophthalmic disorder characterized by typically bilateral, asymmetric, yellowish, punctate chorioretinal lesions of the posterior pole forming a linear branching pattern and progressing to atrophic scars. Subretinal neovascular membranes occur in many cases. Vitritis is always absent. Patients may present with blurred vision, scotoma, floaters, photopsia, and metamorphopsia. Choroidal neovascular membrane formation and subretinal fibrosis are the major causes of visual loss. The condition predominantly occurs in young myopic females.","definition_xrefs":["Orphanet:580951"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"punctate inner choroidopathy","secondary_identifiers":["ICD10CM:H31.0","MEDGEN:152679","GARD:7503","icd11.foundation:1322994548","UMLS:C0730321"],"termid":"MONDO:0035584","xrefs":{"Monarch":{"xref_id":"0035584"}}}


id: PBO:0076057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stomatin like 3","termid":"PBO:0076057"}


id: PBO:0053709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 917","termid":"PBO:0053709"}


id: GO:0070978
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.","definition_xrefs":["GOC:mh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0065003","GO:0008150","GO:0044085"],"is_obsolete":false,"name":"voltage-gated calcium channel complex assembly","termid":"GO:0070978"}


id: GO:0003322
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glandular epithelial cell development","termid":"GO:0002068"},{"relation_name":"part_of","term_name":"pancreatic A cell differentiation","termid":"GO:0003310"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pancreatic A cell development","synonyms":[{"name":"pancreatic alpha cell development","type":"exact"}],"termid":"GO:0003322"}


id: GO:0071080
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.","definition_xrefs":["PMID:9360995"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005886"],"is_obsolete":false,"name":"alpha3-beta1 integrin-basigin complex","synonyms":[{"name":"ITGA3-ITGB1-BSG complex","type":"narrow"}],"termid":"GO:0071080"}


id: MONDO:0023868
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Melanoma-associated retinopathy (MAR) is a rare autoimmune condition that occurs in some people with melanoma (a type of skin cancer) and can affect the vision.","definition_xrefs":["GARD:0012041"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinal disorder","termid":"MONDO:0005283"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"melanoma associated retinopathy","secondary_identifiers":["GARD:12041","SCTID:312941005","MEDGEN:452708","icd11.foundation:2011212045","UMLS:C0730308"],"synonyms":[{"name":"Melanoma Associated Retinopathy","type":"related"},{"name":"Melanoma associated retinopathy","type":"related"},{"name":"Melanoma-Associated Retinopathies","type":"related"},{"name":"Melanoma-Associated Retinopathy","type":"related"},{"name":"Melanoma-associated retinopathy","type":"related"},{"name":"Retinopathies, Melanoma-Associated","type":"related"},{"name":"Retinopathy, Melanoma-Associated","type":"related"}],"termid":"MONDO:0023868","xrefs":{"Monarch":{"xref_id":"0023868"}}}


id: MONDO:0009833
data:
  {"annotated_genes":["SJAG_03684","SJAG_00487","SJAG_04991","SJAG_02171","SJAG_04491"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85473,85474,85472,85475],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044204"},{"annotations":[85225],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044205"}]},"cv_name":"mondo","definition":"Shwachman-Diamond syndrome (SDS) is a rare multisystemic syndrome characterized by chronic and usually mild neutropenia, pancreatic exocrine insufficiency associated with steatorrhea and growth failure, skeletal dysplasia with short stature, and an increased risk of bone marrow aplasia or leukemic transformation.","definition_xrefs":["Orphanet:811"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete metaphyseal dysplasia (obsolete MONDO:0000841)","termid":"MONDO:0000841"},{"relation_name":"excluded_subClassOf","term_name":"inherited aplastic anemia","termid":"MONDO:0001713"},{"relation_name":"excluded_subClassOf","term_name":"pancreas disorder","termid":"MONDO:0002356"},{"relation_name":"excluded_subClassOf","term_name":"obsolete polymalformative genetic syndrome with increased risk of developing cancer (obsolete MONDO:0015945)","termid":"MONDO:0015945"},{"relation_name":"excluded_subClassOf","term_name":"functional neutrophil defect","termid":"MONDO:0015978"},{"relation_name":"excluded_subClassOf","term_name":"obsolete multiple metaphyseal dysplasia (obsolete MONDO:0019693)","termid":"MONDO:0019693"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00487":null,"SJAG_02171":null,"SJAG_03684":null,"SJAG_04491":null,"SJAG_04991":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Shwachman-Diamond syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0272170","DOID:0080023","MEDGEN:124418","NANDO:1200356","NANDO:2200756","NORD:1711","MedDRA:10067940","SCTID:89454001","GARD:4863","MESH:C537330","NCIT:C61235","OMIMPS:260400","icd11.foundation:232885463","DOID:0060479"],"synonyms":[{"name":"SDS","type":"exact"},{"name":"Schwachman-Diamond syndrome","type":"exact"},{"name":"Schwachmann-Diamond syndrome","type":"exact"},{"name":"Shwachman Diamond Syndrome","type":"exact"},{"name":"Shwachman syndrome","type":"exact"},{"name":"Shwachman-Bodian syndrome","type":"related"},{"name":"Shwachman-Bodian-Diamond syndrome","type":"exact"},{"name":"Shwachman-Diamond syndrome","type":"exact"},{"name":"Shwachman-Diamond type metaphyseal dysplasia","type":"related"},{"name":"congenital lipomatosis of pancreas","type":"related"},{"name":"lipomatosis of pancreas, congenital","type":"related"},{"name":"pancreatic insufficiency and bone marrow dysfunction","type":"exact"}],"termid":"MONDO:0009833","terms_by_termid":{"MONDO:0044204":null,"MONDO:0044205":null},"xrefs":{"Monarch":{"xref_id":"0009833"}}}


id: GO:0051648
data:
  {"annotated_genes":["SJAG_03938","SJAG_02320","SJAG_03268","SJAG_03864","SJAG_02166","SJAG_03005","SJAG_01925","SJAG_04960","SJAG_03357","SJAG_04044","SJAG_00938","SJAG_04391","SJAG_03011"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[116871,92425],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0048205"},{"annotations":[117559],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0099022"},{"annotations":[116856,87835,112998,113290,117963,89957,101106,98743],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0090522"},{"annotations":[115319,69324],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030050"}]},"cv_name":"biological_process","definition":"Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle localization","termid":"GO:0051640"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00938":null,"SJAG_01925":null,"SJAG_02166":null,"SJAG_02320":null,"SJAG_03005":null,"SJAG_03011":null,"SJAG_03268":null,"SJAG_03357":null,"SJAG_03864":null,"SJAG_03938":null,"SJAG_04044":null,"SJAG_04391":null,"SJAG_04960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"vesicle localization","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"cytoplasmic vesicle localization","type":"exact"},{"name":"establishment and maintenance of vesicle localization","type":"exact"},{"name":"vesicle localisation","type":"exact"}],"termid":"GO:0051648","terms_by_termid":{"GO:0030050":null,"GO:0048205":null,"GO:0090522":null,"GO:0099022":null}}


id: GO:0170050
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A ribonucleoprotein complex containing a box C/D type snoRNA and three (Archaea) or four (Eukaryotes) core proteins that is capable of methylation of target RNAs.","definition_xrefs":["PMID:28505386","PMID:30254138"],"direct_ancestors":[{"relation_name":"is_a","term_name":"box C/D RNP complex","termid":"GO:0170049"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"box C/D methylation guide RNP complex","termid":"GO:0170050"}


id: PBO:0086299
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with a role in transcriptional silencing; required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; binds with Spt10p to histone gene promoters during S phase; localizes to nuclear foci that become diffuse upon DNA replication stress","termid":"PBO:0086299"}


id: PBO:0058828
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 8058","termid":"PBO:0058828"}


id: GO:0060972
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regionalization","termid":"GO:0003002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"left/right pattern formation","termid":"GO:0060972"}


id: GO:1904819
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.","definition_xrefs":["GOC:dph","PMID:15840053","GOC:TermGenie","GO_REF:0000094"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"peritoneum development","termid":"GO:1904820"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"parietal peritoneum development","synonyms":[{"name":"peritoneal cavity lining development","type":"exact"}],"termid":"GO:1904819"}


id: GO:0046851
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of tissue remodeling","termid":"GO:0034104"},{"relation_name":"is_a","term_name":"regulation of bone remodeling","termid":"GO:0046850"},{"relation_name":"negatively_regulates","term_name":"bone remodeling","termid":"GO:0046849"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of bone remodeling","synonyms":[{"name":"down regulation of bone remodeling","type":"exact"},{"name":"down-regulation of bone remodeling","type":"exact"},{"name":"downregulation of bone remodeling","type":"exact"},{"name":"inhibition of bone remodeling","type":"narrow"},{"name":"negative regulation of bone remodelling","type":"exact"}],"termid":"GO:0046851"}


id: PBO:0052774
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 18 pseudogene 66","termid":"PBO:0052774"}


id: MONDO:0032792
data:
  {"annotated_genes":["SJAG_00252","SJAG_01383"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86182,86183],"is_not":false,"summary":null,"term":"MONDO:0032792"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary motor and sensory neuropathy type 6","termid":"MONDO:0019551"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00252":null,"SJAG_01383":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"neuropathy, hereditary motor and sensory, type VIc, with optic atrophy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1680245","OMIM:618511","UMLS:C5193137"],"synonyms":[{"name":"CMT 6C","type":"exact"},{"name":"CMT6C","type":"exact"},{"name":"Charcot-Marie-Tooth Disease, Type 6C","type":"exact"},{"name":"HMSN 6C","type":"exact"},{"name":"HMSN6C","type":"exact"},{"name":"neuropathy, hereditary motor and sensory, type VIc, with optic atrophy","type":"exact"}],"termid":"MONDO:0032792","terms_by_termid":{"MONDO:0032792":null},"xrefs":{"Monarch":{"xref_id":"0032792"}}}


id: MONDO:0022404
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete retinal ciliopathy due to mutation in Usher gene (obsolete MONDO:0022404)","secondary_identifiers":["Orphanet:156177"],"termid":"MONDO:0022404","xrefs":{"Monarch":{"xref_id":"0022404"}}}


id: GO:0010823
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.","definition_xrefs":["GOC:dph","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of mitochondrion organization (obsolete GO:0010823)","synonyms":[{"name":"negative regulation of mitochondrion organisation","type":"exact"}],"termid":"GO:0010823"}


id: MONDO:0002695
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Formation or presence of a blood clot (thrombus) in the superior sagittal sinus or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, craniocerebral trauma; and neurosurgical procedures. Clinical features are primarily related to the increased intracranial pressure causing headache; nausea; and vomiting. Severe cases can evolve to seizures or coma.","definition_xrefs":["MESH:D020225"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracranial sinus thrombosis","termid":"MONDO:0002692"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sagittal sinus thrombosis","secondary_identifiers":["MEDGEN:90927","SCTID:192760003","UMLS:C0338575","DOID:3576"],"synonyms":[{"name":"thrombosis of superior longitudinal sinus","type":"exact"},{"name":"thrombosis of superior sagittal sinus","type":"exact"}],"termid":"MONDO:0002695","xrefs":{"Monarch":{"xref_id":"0002695"}}}


id: PBO:0027540
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_nucleosome_positioning_at_stress_response_genes","termid":"PBO:0027540"}


id: MONDO:0020769
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Menke-Hennekam syndrome","termid":"MONDO:0020774"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Menke-Hennekam syndrome 2","secondary_identifiers":["OMIM:618333","UMLS:C5193035","MEDGEN:1676668"],"synonyms":[{"name":"MKHK2","type":"related"},{"name":"Menke-Hennekam syndrome 2","type":"exact"}],"termid":"MONDO:0020769","xrefs":{"Monarch":{"xref_id":"0020769"}}}


id: PBO:0072842
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sin3A associated protein 130","termid":"PBO:0072842"}


id: MONDO:0044351
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An disease or disorder caused by infection with Schistosoma intercalatum.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"schistosomiasis","termid":"MONDO:0015254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schistosoma intercalatum infectious disease","secondary_identifiers":["SCTID:52179003","UMLS:C0276932","NCIT:C35364","MEDGEN:124448","ICD9:120.8"],"synonyms":[{"name":"Schistosoma intercalatum caused disease or disorder","type":"exact"},{"name":"Schistosoma intercalatum disease or disorder","type":"exact"},{"name":"infection by Schistosoma intercalatum","type":"exact"},{"name":"infection caused by Schistosoma intercalatum","type":"related"}],"termid":"MONDO:0044351","xrefs":{"Monarch":{"xref_id":"0044351"}}}


id: MONDO:0021242
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm (disease) that involves the sublingual gland.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm of major salivary gland","termid":"MONDO:0021368"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sublingual gland neoplasm","secondary_identifiers":["MESH:D013362","SCTID:126790004","MEDGEN:21371","NCIT:C3392","UMLS:C0038554"],"synonyms":[{"name":"neoplasm of sublingual gland","type":"exact"},{"name":"neoplasm of the sublingual gland","type":"exact"},{"name":"sublingual gland neoplasm (disease)","type":"exact"},{"name":"sublingual gland tumor","type":"exact"},{"name":"sublingual gland tumour","type":"exact"},{"name":"tumor of sublingual gland","type":"exact"},{"name":"tumor of the sublingual gland","type":"exact"},{"name":"tumour of sublingual gland","type":"exact"},{"name":"tumour of the sublingual gland","type":"exact"}],"termid":"MONDO:0021242","xrefs":{"Monarch":{"xref_id":"0021242"}}}


id: GO:0035007
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of secondary metabolic process","termid":"GO:0043455"},{"relation_name":"is_a","term_name":"regulation of innate immune response","termid":"GO:0045088"},{"relation_name":"regulates","term_name":"melanization defense response","termid":"GO:0035006"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"regulation of melanization defense response","synonyms":[{"name":"regulation of melanization defence response","type":"exact"}],"termid":"GO:0035007"}


id: PBO:0046638
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group W member 19","termid":"PBO:0046638"}


id: GO:0031470
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO2. It augments the concentration of CO2 in the vicinity of RuBisCO to increase the efficiency of CO2 fixation under atmospheric conditions.","definition_xrefs":["PMID:8157606","GOC:js","PMID:28934381","PMID:8491708"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial microcompartment","termid":"GO:0031469"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"carboxysome","secondary_identifiers":["Wikipedia:Carboxysome"],"termid":"GO:0031470"}


id: MONDO:0001374
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant mesenchymal cell neoplasm that affects the urinary bladder.","definition_xrefs":["NCIT:C4669"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urinary bladder cancer","termid":"MONDO:0001187"},{"relation_name":"is_a","term_name":"soft tissue sarcoma","termid":"MONDO:0018078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"bladder sarcoma","secondary_identifiers":["UMLS:C0349666","DOID:11812","SCTID:278046008","MEDGEN:87612"],"synonyms":[{"name":"bladder sarcoma","type":"exact"},{"name":"sarcoma of bladder","type":"exact"},{"name":"sarcoma of the bladder","type":"exact"},{"name":"sarcoma of the urinary bladder","type":"exact"},{"name":"sarcoma of urinary bladder","type":"exact"},{"name":"urinary bladder sarcoma","type":"exact"}],"termid":"MONDO:0001374","xrefs":{"Monarch":{"xref_id":"0001374"}}}


id: PBO:0110234
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BouQueT formation protein","termid":"PBO:0110234"}


id: PBO:0000905
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GDP dissociation inhibitor Rdi1 (predicted)","termid":"PBO:0000905"}


id: PBO:0075731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"signal recognition particle 14","termid":"PBO:0075731"}


id: GO:0061387
data:
  {"annotated_genes":["SJAG_03602"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[97632],"is_not":false,"summary":null,"term":"GO:0061387"}]},"cv_name":"biological_process","definition":"Any process that modulates the extent of cell growth.","definition_xrefs":["GOC:mah","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell growth","termid":"GO:0001558"},{"relation_name":"part_of","term_name":"regulation of cell size","termid":"GO:0008361"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03602":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of extent of cell growth","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0061387","terms_by_termid":{"GO:0061387":null}}


id: MONDO:0030819
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Meckel syndrome","termid":"MONDO:0018921"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meckel syndrome 14","secondary_identifiers":["MEDGEN:1809650","UMLS:C5676989","OMIM:619879"],"synonyms":[{"name":"MKS14","type":"exact"},{"name":"meckel syndrome 14","type":"exact"}],"termid":"MONDO:0030819","xrefs":{"Monarch":{"xref_id":"0030819"}}}


id: PBO:0069761
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1044, pseudogene","termid":"PBO:0069761"}


id: PBO:0052197
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium calcium-activated channel subfamily N member 1","termid":"PBO:0052197"}


id: MONDO:0002974
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm involving the cervix.","definition_xrefs":["NCIT:C9311"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uterine cancer","termid":"MONDO:0002715"},{"relation_name":"is_a","term_name":"uterine cervix neoplasm","termid":"MONDO:0021230"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"cervical cancer","secondary_identifiers":["ICD9:180.9","SCTID:363354003","UMLS:C4048328","MEDGEN:890252","OMIM:603956","DOID:4362","ICD9:180","ICD9:180.8"],"synonyms":[{"name":"cancer of uterine cervix","type":"exact"},{"name":"cervical cancer, somatic","type":"exact"},{"name":"cervical neoplasm","type":"broad"},{"name":"cervix cancer","type":"exact"},{"name":"cervix uteri cancer","type":"exact"},{"name":"malignant cervical neoplasm","type":"exact"},{"name":"malignant cervical tumor","type":"exact"},{"name":"malignant cervical tumour","type":"exact"},{"name":"malignant cervix neoplasm","type":"exact"},{"name":"malignant cervix tumor","type":"exact"},{"name":"malignant cervix tumour","type":"exact"},{"name":"malignant cervix uteri neoplasm","type":"exact"},{"name":"malignant cervix uteri tumor","type":"exact"},{"name":"malignant cervix uteri tumour","type":"exact"},{"name":"malignant neoplasm of cervix","type":"exact"},{"name":"malignant neoplasm of cervix uteri","type":"exact"},{"name":"malignant neoplasm of the cervix","type":"exact"},{"name":"malignant neoplasm of the cervix uteri","type":"exact"},{"name":"malignant neoplasm of the uterine cervix","type":"exact"},{"name":"malignant neoplasm of uterine cervix","type":"exact"},{"name":"malignant tumor of cervix","type":"exact"},{"name":"malignant tumor of cervix uteri","type":"exact"},{"name":"malignant tumor of the cervix","type":"exact"},{"name":"malignant tumor of the cervix uteri","type":"exact"},{"name":"malignant tumor of the uterine cervix","type":"exact"},{"name":"malignant tumor of uterine cervix","type":"exact"},{"name":"malignant tumour of cervix","type":"exact"},{"name":"malignant tumour of cervix uteri","type":"exact"},{"name":"malignant tumour of the cervix","type":"exact"},{"name":"malignant tumour of the cervix uteri","type":"exact"},{"name":"malignant tumour of the uterine cervix","type":"exact"},{"name":"malignant tumour of uterine cervix","type":"exact"},{"name":"malignant uterine cervix neoplasm","type":"exact"},{"name":"malignant uterine cervix tumor","type":"exact"},{"name":"malignant uterine cervix tumour","type":"exact"},{"name":"tumor of the cervix uteri","type":"broad"},{"name":"tumour of the cervix uteri","type":"broad"},{"name":"uterine cervical neoplasm","type":"broad"},{"name":"uterine cervix cancer","type":"exact"}],"termid":"MONDO:0002974","xrefs":{"Monarch":{"xref_id":"0002974"}}}


id: MONDO:0004006
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An exceptionally rare cystadenofibroma that arises from the rete ovarii.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovarian benign neoplasm","termid":"MONDO:0000646"},{"relation_name":"is_a","term_name":"rete ovarii neoplasm","termid":"MONDO:0003192"},{"relation_name":"is_a","term_name":"cystadenofibroma","termid":"MONDO:0003464"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rete ovarii cystadenofibroma","secondary_identifiers":["DOID:6838","NCIT:C40020","UMLS:C1514906","MEDGEN:308159"],"synonyms":[{"name":"cystadenofibroma of rete ovarii","type":"exact"},{"name":"rete ovarii cystadenofibroma","type":"exact"}],"termid":"MONDO:0004006","xrefs":{"Monarch":{"xref_id":"0004006"}}}


id: MONDO:0010574
data:
  {"annotated_genes":["SJAG_00379"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86104],"is_not":false,"summary":null,"term":"MONDO:0010574"}]},"cv_name":"mondo","definition":"X-linked Dandy-Walker malformation with intellectual disability, basal ganglia disease and seizures (XDIBS), or Pettigrew syndrome is a central nervous system malformation characterized by severe intellectual deficit, early hypotonia with progression to spasticity and contractures, choreoathetosis, seizures, dysmorphic face (long face with prominent forehead), and brain imaging abnormalities such as Dandy-Walker malformation, and iron deposition.","definition_xrefs":["Orphanet:1568"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"central nervous system malformation","termid":"MONDO:0020022"},{"relation_name":"is_a","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00379":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022","MONDO:0002320"],"is_obsolete":false,"name":"syndromic X-linked intellectual disability 5","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:85329","SCTID:719139003","GARD:8520","NCIT:C124839","DOID:0060800","UMLS:C0796254","MEDGEN:162924","OMIM:304340"],"synonyms":[{"name":"Dandy-Walker malformation with intellectual disability, basal ganglia disease and seizures","type":"related"},{"name":"MRX59","type":"exact"},{"name":"MRXS21","type":"exact"},{"name":"MRXS5","type":"related"},{"name":"PETTIGREW syndrome","type":"related"},{"name":"PGS","type":"related"},{"name":"Pettigrew syndrome","type":"exact"},{"name":"Pettigrew syndrome, X-linked recessive","type":"exact"},{"name":"X-linked intellectual disability - Dandy-Walker malformation - basal ganglia disease - seizures","type":"related"},{"name":"X-linked intellectual disability 59","type":"exact"},{"name":"X-linked intellectual disability-Dandy-Walker malformation-basal ganglia disease-seizures syndrome","type":"exact"},{"name":"X-linked intellectual disability-hypotonia-facial dysmorphism-aggressive behavior syndrome","type":"exact"},{"name":"X-linked intellectual disability-hypotonia-facial dysmorphism-aggressive behaviour syndrome","type":"exact"},{"name":"X-linked mental retardation 59","type":"exact"},{"name":"X-linked metal retardation with Dandy-Walker malformation, basal ganglia disease, and seizures","type":"exact"},{"name":"fried syndrome","type":"related"},{"name":"intellectual disability X-linked syndromic 5","type":"related"},{"name":"intellectual disability X-linked with Dandy-Walker malformation basal ganglia disease and seizures","type":"related"},{"name":"intellectual disability, X-linked 59","type":"related"},{"name":"intellectual disability, X-linked syndromic 5","type":"exact"},{"name":"intellectual disability, X-linked, syndromic 21","type":"related"},{"name":"intellectual disability, X-linked, syndromic 5","type":"related"},{"name":"intellectual disability, X-linked, syndromic, fried type","type":"related"},{"name":"intellectual disability, X-linked, with Dandy-Walker malformation, basal ganglia disease, and seizures","type":"related"},{"name":"mental retardation X-linked syndromic 5","type":"related"},{"name":"mental retardation X-linked with Dandy-Walker malformation basal ganglia disease and seizures","type":"related"},{"name":"mental retardation, X-linked 59","type":"related"},{"name":"mental retardation, X-linked syndromic 5","type":"exact"},{"name":"mental retardation, X-linked, syndromic 21","type":"related"},{"name":"mental retardation, X-linked, syndromic 5","type":"related"},{"name":"mental retardation, X-linked, syndromic, fried type","type":"related"},{"name":"mental retardation, X-linked, with Dandy-Walker malformation, basal ganglia disease, and seizures","type":"related"},{"name":"syndromic X-linked intellectual disability 21","type":"exact"},{"name":"syndromic X-linked intellectual disability fried type","type":"exact"},{"name":"syndromic X-linked intellectual disability type 5","type":"exact"},{"name":"syndromic X-linked mental retardation 21","type":"exact"},{"name":"syndromic X-linked mental retardation fried type","type":"exact"}],"termid":"MONDO:0010574","terms_by_termid":{"MONDO:0010574":null},"xrefs":{"Monarch":{"xref_id":"0010574"}}}


id: PBO:0054264
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1649","termid":"PBO:0054264"}


id: MONDO:0007543
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete enolase, sperm specific (obsolete MONDO:0007543)","termid":"MONDO:0007543","xrefs":{"Monarch":{"xref_id":"0007543"}}}


id: MONDO:0700185
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes that occurs in a cat.","definition_xrefs":["NCIT:C156362"],"direct_ancestors":[{"relation_name":"is_a","term_name":"melanoma, non-human animal","termid":"MONDO:0700132"},{"relation_name":"is_a","term_name":"feline neoplasm","termid":"MONDO:0700175"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"feline melanoma","termid":"MONDO:0700185","xrefs":{"Monarch":{"xref_id":"0700185"}}}


id: GO:0004241
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete alpha-mitochondrial processing peptidase (obsolete GO:0004241)","synonyms":[{"name":"alpha-MPP","type":"exact"},{"name":"alpha-mitochondrial processing peptidase","type":"exact"}],"termid":"GO:0004241"}


id: MONDO:0017041
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Osteochondrodysplatic nanism-deafness-retinitis pigmentosa syndrome is characterized by severe dwarfism, progressive scoliosis and bilateral dislocation of the hip, associated with sensorineural deafness and retinitis pigmentosa. Radiographs show diffuse osteoporosis, severe bone-age delay and dysplasia of the femoral head. It has been described in two patients. Transmission is autosomal dominant variable penetrance.","definition_xrefs":["Orphanet:2653"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"disorder of visual system","termid":"MONDO:0024458"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteochondrodysplatic nanism-deafness-retinitis pigmentosa syndrome","secondary_identifiers":["MEDGEN:928494","UMLS:C4302825","GARD:18776","SCTID:722108000"],"synonyms":[{"name":"Osteochondrodysplatic dwarfism-deafness-retinitis pigmentosa syndrome","type":"exact"}],"termid":"MONDO:0017041","xrefs":{"Monarch":{"xref_id":"0017041"}}}


id: PBO:0108922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMX1 pseudogene 2","termid":"PBO:0108922"}


id: RO:0002375
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.","direct_ancestors":[{"relation_name":"is_a","term_name":"part_of","termid":"BFO:0000050"},{"relation_name":"is_a","term_name":"mereotopologically_related_to","termid":"RO:0002323"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_branching_relationship_with","termid":"RO:0002375"}


id: PBO:0091717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinetochore protein Mis19/Eic1","termid":"PBO:0091717"}


id: GO:0061550
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ganglion development","termid":"GO:0061548"},{"relation_name":"part_of","term_name":"cranial nerve development","termid":"GO:0021545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cranial ganglion development","synonyms":[{"name":"cranial ganglia development","type":"related"}],"termid":"GO:0061550"}


id: PBO:0091746
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome b translation regulator Cbp7","termid":"PBO:0091746"}


id: PBO:0081700
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 622","termid":"PBO:0081700"}


id: PBO:0074496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptosome associated protein 25","termid":"PBO:0074496"}


id: PBO:0044853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 134","termid":"PBO:0044853"}


id: PBO:0077123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TIMP metallopeptidase inhibitor 2","termid":"PBO:0077123"}


id: GO:0097445
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered.","definition_xrefs":["NIF_Subcellular:sao494258938","PMID:15381754"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"presynaptic active zone","termid":"GO:0048786"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"presynaptic active zone dense projection","synonyms":[{"name":"active zone dense projection","type":"exact"},{"name":"pre-synaptic active zone dense projection","type":"exact"}],"termid":"GO:0097445"}


id: GO:0050058
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate.","definition_xrefs":["RHEA:17381","EC:5.2.1.5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cis-trans isomerase activity","termid":"GO:0016859"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016853","GO:0003674"],"is_obsolete":false,"name":"linoleate isomerase activity","secondary_identifiers":["KEGG_REACTION:R03627","MetaCyc:LINOLEATE-ISOMERASE-RXN"],"synonyms":[{"name":"linoleate delta12-cis-delta11-trans-isomerase activity","type":"related"},{"name":"linoleic acid isomerase activity","type":"related"}],"termid":"GO:0050058"}


id: MONDO:0003724
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Breast fibrocystic change characterized by the absence of epithelial cell hyperplasia.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"breast fibrocystic disease","termid":"MONDO:0005219"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-proliferative fibrocystic change of the breast","secondary_identifiers":["UMLS:C1332628","MEDGEN:231966","DOID:5997","NCIT:C6943"],"synonyms":[{"name":"breast fibrocystic change, non-proliferative type","type":"exact"},{"name":"non-proliferative fibrocystic change","type":"exact"},{"name":"non-proliferative fibrocystic change of breast","type":"exact"}],"termid":"MONDO:0003724","xrefs":{"Monarch":{"xref_id":"0003724"}}}


id: MONDO:0008013
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Monosomy 9p is a rare chromosomal anomaly characterized by psychomotor developmental delay, facial dysmorphism (trigonocephaly, midface hypoplasia, upslanting palpebral fissures, dysplastic small ears, flat nasal bridge with anteverted nostrils and long philtrum, micrognathia, choanal atresia, short neck), single umbilical artery, omphalocele, inguinal or umbilical hernia, genital abnormalities (hypospadia, cryptorchidism), muscular hypotonia and scoliosis.","definition_xrefs":["Orphanet:261112"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of chromosome 9","termid":"MONDO:0016874"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 9p deletion syndrome","secondary_identifiers":["MEDGEN:167073","UMLS:C0795830","MESH:C538024","GARD:3773","ICD9:758.39","DOID:0060732","SCTID:62599000","OMIM:158170"],"synonyms":[{"name":"9p deletion","type":"exact"},{"name":"9p deletion syndrome","type":"exact"},{"name":"9p monosomy","type":"exact"},{"name":"9p syndrome","type":"exact"},{"name":"9p- syndrome","type":"exact"},{"name":"Alfi syndrome","type":"exact"},{"name":"chromosome 9p deletion","type":"exact"},{"name":"deletion 9p","type":"exact"},{"name":"monosomy 9p","type":"exact"},{"name":"monosomy 9p syndrome","type":"exact"},{"name":"monosomy type 9p","type":"exact"},{"name":"partial deletion of chromosome 9p","type":"exact"},{"name":"partial deletion of the short arm of chromosome 9","type":"exact"},{"name":"partial deletion of the short arm of chromosome type 9","type":"exact"},{"name":"partial monosomy 9p","type":"exact"},{"name":"partial monosomy of chromosome 9p","type":"exact"},{"name":"partial monosomy of the short arm of chromosome 9","type":"exact"}],"termid":"MONDO:0008013","xrefs":{"Monarch":{"xref_id":"0008013"}}}


id: GO:0030267
data:
  {"annotated_genes":["SJAG_01432","SJAG_00281"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[100216,104251],"is_not":false,"summary":null,"term":"GO:0030267"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.","definition_xrefs":["RHEA:10992"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glyoxylate reductase activity","termid":"GO:0106345"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00281":null,"SJAG_01432":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"glyoxylate reductase (NADPH) activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Wikipedia:Glyoxylate_reductase_(NADP+)","Reactome:R-HSA-389826","MetaCyc:GLYOXYLATE-REDUCTASE-NADP+-RXN","EC:1.1.1.79"],"synonyms":[{"name":"NADPH-glyoxylate reductase activity","type":"related"},{"name":"glycolate:NADP+ oxidoreductase activity","type":"related"},{"name":"glyoxylate reductase (NADP+)","type":"related"}],"termid":"GO:0030267","terms_by_termid":{"GO:0030267":null}}


id: GO:0070859
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of steroid biosynthetic process","termid":"GO:0010893"},{"relation_name":"is_a","term_name":"regulation of bile acid biosynthetic process","termid":"GO:0070857"},{"relation_name":"is_a","term_name":"positive regulation of bile acid metabolic process","termid":"GO:1904253"},{"relation_name":"positively_regulates","term_name":"bile acid biosynthetic process","termid":"GO:0006699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006629"},{"rel_name":"positively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006629","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"positive regulation of bile acid biosynthetic process","synonyms":[{"name":"activation of bile acid biosynthetic process","type":"narrow"},{"name":"positive regulation of bile acid anabolism","type":"exact"},{"name":"positive regulation of bile acid biosynthesis","type":"exact"},{"name":"positive regulation of bile acid formation","type":"exact"},{"name":"positive regulation of bile acid synthesis","type":"exact"},{"name":"stimulation of bile acid biosynthetic process","type":"narrow"},{"name":"up regulation of bile acid biosynthetic process","type":"exact"},{"name":"up-regulation of bile acid biosynthetic process","type":"exact"},{"name":"upregulation of bile acid biosynthetic process","type":"exact"}],"termid":"GO:0070859"}


id: RO:HOM0000001
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Similarity that results from common evolutionary origin.","direct_ancestors":[{"relation_name":"is_a","term_name":"shares_ancestor_with","termid":"RO:0002158"},{"relation_name":"is_a","term_name":"in_similarity_relationship_with","termid":"RO:HOM0000000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_homology_relationship_with","synonyms":[{"name":"homologous to","type":"exact"}],"termid":"RO:HOM0000001"}


id: PR:Q09828
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A leucine--tRNA ligase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00303","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine--tRNA ligase, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4G8.09","secondary_identifiers":["UniProtKB:Q09828"],"synonyms":[{"name":"LeuRS (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-LARS2","type":"exact"},{"name":"leucyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q09828"}


id: PR:Q9C121
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC1002.20 gene.","definition_xrefs":["UniProtKB:Q9C121","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C1002.20 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.20","synonyms":[{"name":"Spom972h-SPAC1002.20","type":"exact"}],"termid":"PR:Q9C121"}


id: GO:0048246
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The movement of a macrophage in response to an external stimulus.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte chemotaxis","termid":"GO:0030595"},{"relation_name":"is_a","term_name":"macrophage migration","termid":"GO:1905517"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"macrophage chemotaxis","termid":"GO:0048246"}


id: PBO:0066315
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RBPMS antisense RNA 1","termid":"PBO:0066315"}


id: MONDO:0002972
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the posterior mediastinum.","direct_ancestors":[{"relation_name":"is_a","term_name":"mediastinal cancer","termid":"MONDO:0005843"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"posterior mediastinum cancer","secondary_identifiers":["SCTID:448670003","UMLS:C0153502","ICD9:164.3","MEDGEN:509314","DOID:436"],"synonyms":[{"name":"cancer of posterior mediastinum","type":"exact"},{"name":"malignant neoplasm of posterior mediastinum","type":"exact"},{"name":"malignant posterior mediastinum neoplasm","type":"exact"},{"name":"posterior mediastinum cancer","type":"exact"}],"termid":"MONDO:0002972","xrefs":{"Monarch":{"xref_id":"0002972"}}}


id: MONDO:0016316
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Mucopolysaccharidosis type 2, attenuated form (MPS2att), the less severe form of MPS2, leads to a massive accumulation of glycosaminoglycans and a wide variety of symptoms including distinctive facies, short stature, cardiorespiratory and skeletal findings. It is differentiated from mucopolysaccharidosis type 2, severe form by the absence of cognitive decline.","definition_xrefs":["Orphanet:217093"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mucopolysaccharidosis type 2","termid":"MONDO:0010674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0002561","MONDO:0037792","MONDO:0005066"],"is_obsolete":false,"name":"mucopolysaccharidosis type 2, attenuated form","secondary_identifiers":["SCTID:5667009","UMLS:C5679815","GARD:17119","MEDGEN:1826165","NANDO:1200099","NANDO:2201171","NANDO:2201172"],"synonyms":[{"name":"Hunter syndrome type B","type":"exact"},{"name":"MPS2B","type":"exact"},{"name":"MPSIIB","type":"exact"},{"name":"iduronate 2-sulfatase deficiency type B","type":"exact"},{"name":"mucopolysaccharidosis type 2, attenuated form","type":"exact"},{"name":"mucopolysaccharidosis type 2B","type":"exact"},{"name":"mucopolysaccharidosis type II, attenuated form","type":"exact"},{"name":"mucopolysaccharidosis type IIB","type":"exact"}],"termid":"MONDO:0016316","xrefs":{"Monarch":{"xref_id":"0016316"}}}


id: PBO:0048689
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GLIPR1 like 1","termid":"PBO:0048689"}


id: GO:0014032
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.","definition_xrefs":["GOC:dh","GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stem cell development","termid":"GO:0048864"},{"relation_name":"part_of","term_name":"neural crest cell differentiation","termid":"GO:0014033"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neural crest cell development","termid":"GO:0014032"}


id: PBO:0031249
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_cell_wall_organization_during_vegetative_growth","termid":"PBO:0031249"}


id: PBO:0040239
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activating transcription factor 7 interacting protein","termid":"PBO:0040239"}


id: MONDO:0004481
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A pancreatic intraductal papillary mucinous neoplasm characterized by the presence of a focal or multifocal invasive carcinomatous component. The invasive carcinoma is either colloid or ductal adenocarcinoma.","definition_xrefs":["NCIT:C5726"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreatic intraductal papillary-mucinous carcinoma","termid":"MONDO:0004285"},{"relation_name":"is_a","term_name":"pancreatic intraductal papillary-mucinous neoplasm","termid":"MONDO:0004286"},{"relation_name":"is_a","term_name":"pancreatic adenocarcinoma","termid":"MONDO:0006047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"pancreatic intraductal papillary-mucinous neoplasm with an associated invasive carcinoma","secondary_identifiers":["MEDGEN:275329","ICDO:8453/3","DOID:8150","UMLS:C1518871"],"synonyms":[{"name":"pancreatic intraductal papillary mucinous neoplasm with an associated invasive carcinoma","type":"exact"},{"name":"pancreatic intraductal papillary-mucinous neoplasm with an associated invasive carcinoma","type":"exact"},{"name":"pancreatic invasive intraductal papillary-mucinous carcinoma","type":"exact"}],"termid":"MONDO:0004481","xrefs":{"Monarch":{"xref_id":"0004481"}}}


id: PBO:0043443
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calponin 2 pseudogene 3","termid":"PBO:0043443"}


id: GO:0019269
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate synthase (NADPH).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete glutamate biosynthetic process, using glutamate synthase (NADPH) (obsolete GO:0019269)","synonyms":[{"name":"glutamate anabolism, using glutamate synthase (NADPH)","type":"exact"},{"name":"glutamate biosynthetic process, using glutamate synthase (NADPH)","type":"exact"},{"name":"glutamate formation, using glutamate synthase (NADPH)","type":"exact"},{"name":"glutamate synthesis, using glutamate synthase (NADPH)","type":"exact"}],"termid":"GO:0019269"}


id: PBO:0040478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ataxin 1 like","termid":"PBO:0040478"}


id: PR:O43030
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fes1 gene.","definition_xrefs":["UniProtKB:O43030","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hsp70 nucleotide exchange factor fes1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC3B9.01","synonyms":[{"name":"Spom972h-fes1","type":"exact"}],"termid":"PR:O43030"}


id: GO:0030514
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of BMP signaling pathway","termid":"GO:0030510"},{"relation_name":"is_a","term_name":"negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","termid":"GO:0090101"},{"relation_name":"is_a","term_name":"negative regulation of cellular response to growth factor stimulus","termid":"GO:0090288"},{"relation_name":"negatively_regulates","term_name":"BMP signaling pathway","termid":"GO:0030509"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of BMP signaling pathway","secondary_identifiers":["GO:0090099"],"synonyms":[{"name":"down regulation of BMP signaling pathway","type":"exact"},{"name":"down-regulation of BMP signaling pathway","type":"exact"},{"name":"downregulation of BMP signaling pathway","type":"exact"},{"name":"inhibition of BMP signaling pathway","type":"narrow"},{"name":"negative regulation of BMP receptor signaling pathway","type":"related"},{"name":"negative regulation of BMP signalling pathway","type":"exact"},{"name":"negative regulation of bone morphogenetic protein signaling pathway","type":"exact"},{"name":"negative regulation of bone morphogenetic protein signalling pathway","type":"exact"},{"name":"negative regulation of decapentaplegic receptor signaling pathway","type":"narrow"},{"name":"negative regulation of decapentaplegic receptor signalling pathway","type":"narrow"},{"name":"negative regulation of decapentaplegic signaling pathway","type":"narrow"}],"termid":"GO:0030514"}


id: PBO:0001405
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"targets correlated with Clr3 and Sir2 targets","termid":"PBO:0001405"}


id: PBO:0044155
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CTDP1 divergent transcript","termid":"PBO:0044155"}


id: GO:1903831
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any signal transduction that is involved in cellular response to ammonium ion.","definition_xrefs":["PMID:16297994","GOC:TermGenie","GO_REF:0000060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signal transduction","termid":"GO:0007165"},{"relation_name":"part_of","term_name":"cellular response to ammonium ion","termid":"GO:0071242"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"signal transduction involved in cellular response to ammonium ion","synonyms":[{"name":"signaling cascade involved in cellular response to ammonium ion","type":"narrow"},{"name":"signaling pathway involved in cellular response to ammonium ion","type":"related"},{"name":"signalling cascade involved in cellular response to ammonium ion","type":"narrow"},{"name":"signalling pathway involved in cellular response to ammonium ion","type":"related"}],"termid":"GO:1903831"}


id: GO:0099022
data:
  {"annotated_genes":["SJAG_04044","SJAG_03357","SJAG_02166","SJAG_03938","SJAG_02320","SJAG_01925","SJAG_04960","SJAG_03864","SJAG_03005"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117559],"is_not":false,"summary":null,"term":"GO:0099022"},{"annotations":[116856,87835,98743,117963,101106,112998,89957,113290],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090522"}]},"cv_name":"biological_process","definition":"The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.","definition_xrefs":["PMID:27243008"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component organization","termid":"GO:0016043"},{"relation_name":"part_of","term_name":"vesicle targeting","termid":"GO:0006903"}],"gene_count":9,"genes_by_uniquename":{"SJAG_01925":null,"SJAG_02166":null,"SJAG_02320":null,"SJAG_03005":null,"SJAG_03357":null,"SJAG_03864":null,"SJAG_03938":null,"SJAG_04044":null,"SJAG_04960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0016192"],"is_obsolete":false,"name":"vesicle tethering","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0099022","terms_by_termid":{"GO:0090522":null,"GO:0099022":null}}


id: PBO:0089647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pig-F/3-ketosphinganine reductase fusion protein","termid":"PBO:0089647"}


id: FYPO:0001306
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which long-chain fatty acid-CoA ligase activity is absent.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished catalytic activity","termid":"FYPO:0000664"},{"relation_name":"is_a","term_name":"abnormal long-chain fatty acid-CoA ligase activity","termid":"FYPO:0001305"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000661","FYPO:0000707","FYPO:0000652","FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0000654"],"is_obsolete":false,"name":"abolished long-chain fatty acid-CoA ligase activity","synonyms":[{"name":"abolished lcfa-ligase activity","type":"exact"},{"name":"long-chain fatty acid-CoA ligase activity abolished","type":"exact"}],"termid":"FYPO:0001306"}


id: PBO:0053095
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"late cornified envelope 3C","termid":"PBO:0053095"}


id: PBO:0089757
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMARCAD1 family ATPase Fft3","termid":"PBO:0089757"}


id: MONDO:0013476
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the CALR3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"hypertrophic cardiomyopathy 19","secondary_identifiers":["DOID:0110325","OMIM:613875"],"synonyms":[{"name":"CALR3 hypertrophic cardiomyopathy","type":"exact"},{"name":"CMH19","type":"exact"},{"name":"cardiomyopathy familial hypertrophic 19","type":"exact"},{"name":"cardiomyopathy, familial hypertrophic, 19","type":"related"},{"name":"cardiomyopathy, familial hypertrophic, type 19","type":"exact"},{"name":"hypertrophic cardiomyopathy caused by mutation in CALR3","type":"exact"},{"name":"hypertrophic cardiomyopathy type 19","type":"exact"}],"termid":"MONDO:0013476","xrefs":{"Monarch":{"xref_id":"0013476"}}}


