# terms

id: PR:Q9USM3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sfh1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9USM3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromatin structure-remodeling complex subunit sfh1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC16A11.14","synonyms":[{"name":"RSC complex subunit sfh1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SNF5 homolog 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-sfh1","type":"exact"}],"termid":"PR:Q9USM3"}


id: PATO:0000895
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000895 f1 fertility value (obsolete PATO:0000895)","termid":"PATO:0000895"}


id: PBO:0061613
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear distribution C pseudogene 1","termid":"PBO:0061613"}


id: MONDO:0044785
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A melanoma of the skin characterized by a proliferation of atypical spindled melanocytes in the dermis, in a background of abundant collagen. It usually presents as an amelanotic raised nodular lesion.","definition_xrefs":["NCIT:C37257"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cutaneous melanoma","termid":"MONDO:0005012"},{"relation_name":"is_a","term_name":"spindle cell melanoma","termid":"MONDO:0006427"},{"relation_name":"is_a","term_name":"malignant spindle cell neoplasm","termid":"MONDO:0020663"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0004992"],"is_obsolete":false,"name":"desmoplastic melanoma","secondary_identifiers":["ONCOTREE:DESM","UMLS:C1333280","MEDGEN:232127"],"synonyms":[{"name":"desmoplastic cutaneous (skin) melanoma","type":"exact"},{"name":"desmoplastic melanoma","type":"exact"}],"termid":"MONDO:0044785","xrefs":{"Monarch":{"xref_id":"0044785"}}}


id: PBO:0036351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3'-5'- exoribonuclease Rex1 (predicted)","termid":"PBO:0036351"}


id: PBO:0074604
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 11E","termid":"PBO:0074604"}


id: GO:0008901
data:
  {"annotated_genes":["SJAG_02497"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[113899],"is_not":false,"summary":null,"term":"GO:0008901"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.","definition_xrefs":["EC:1.12.7.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor","termid":"GO:0016699"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02497":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"ferredoxin hydrogenase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0016949","GO:0016948","GO:0016951","GO:0016950","RHEA:17445","MetaCyc:HYDROG-RXN"],"synonyms":[{"name":"H(2) oxidizing hydrogenase activity","type":"broad"},{"name":"H(2) producing hydrogenase activity","type":"broad"},{"name":"H2 oxidizing hydrogenase","type":"broad"},{"name":"H2 producing hydrogenase","type":"broad"},{"name":"Ni-Fe hydrogenase activity","type":"narrow"},{"name":"Ni-Fe-Se hydrogenase activity","type":"narrow"},{"name":"[Fe] hydrogenase activity","type":"exact"},{"name":"[Fe] hydrogenase gamma","type":"related"},{"name":"bidirectional hydrogenase activity","type":"broad"},{"name":"hydrogen-lyase activity","type":"broad"},{"name":"hydrogen:ferredoxin oxidoreductase activity","type":"exact"},{"name":"hydrogenase (ferredoxin) activity","type":"related"},{"name":"hydrogenase I","type":"related"},{"name":"hydrogenase II","type":"related"},{"name":"hydrogenase activity","type":"broad"},{"name":"hydrogenlyase activity","type":"broad"},{"name":"iron hydrogenase activity","type":"narrow"},{"name":"iron-only hydrogenase activity","type":"narrow"},{"name":"nickel hydrogenase activity","type":"narrow"},{"name":"nickel-iron hydrogenase activity","type":"narrow"},{"name":"nickel-iron-selenium hydrogenase activity","type":"narrow"},{"name":"uptake hydrogenase activity","type":"broad"}],"termid":"GO:0008901","terms_by_termid":{"GO:0008901":null}}


id: GO:1905892
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to thapsigargin.","definition_xrefs":["GOC:aruk","GOC:TermGenie","PMID:21803450","GO_REF:0000058","GOC:bc"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of cellular response to thapsigargin (obsolete GO:1905892)","synonyms":[{"name":"down regulation of cellular response to thapsigargin","type":"exact"},{"name":"down-regulation of cellular response to thapsigargin","type":"exact"},{"name":"downregulation of cellular response to thapsigargin","type":"exact"},{"name":"inhibition of cellular response to thapsigargin","type":"narrow"}],"termid":"GO:1905892"}


id: PBO:0003642
data:
  {"annotation_feature_type":"gene","cv_name":"DNA_binding_specificity","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"binds FLEX 5'-GTAAAYA-3'","termid":"PBO:0003642"}


id: GO:0097018
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron.","definition_xrefs":["GOC:yaf","PMID:18431508"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal protein absorption","termid":"GO:0097017"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"renal albumin absorption","termid":"GO:0097018"}


id: GO:0046011
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.","definition_xrefs":["GOC:go_curators","PMID:12538512"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of translation","termid":"GO:0006417"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of oskar mRNA translation","termid":"GO:0046011"}


id: PBO:0057152
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 300","termid":"PBO:0057152"}


id: GO:0102369
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ = 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O.","definition_xrefs":["GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","termid":"GO:0016705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"11alpha-30-dihydroxy beta-amyrin dehydrogenase activity","secondary_identifiers":["MetaCyc:RXN-13491"],"termid":"GO:0102369"}


id: PBO:0056712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MEMO1 pseudogene 4","termid":"PBO:0056712"}


id: GO:1902175
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.","definition_xrefs":["GOC:mtg_apoptosis","GOC:BHF","PMID:11672522","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of intrinsic apoptotic signaling pathway","termid":"GO:2001242"},{"relation_name":"regulates","term_name":"intrinsic apoptotic signaling pathway in response to oxidative stress","termid":"GO:0008631"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","synonyms":[{"name":"regulation of intrinsic apoptotic signaling pathway in response to oxidative stress","type":"exact"}],"termid":"GO:1902175"}


id: GO:0030729
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H+.","definition_xrefs":["EC:6.2.1.16","RHEA:16117"],"direct_ancestors":[{"relation_name":"is_a","term_name":"CoA-ligase activity","termid":"GO:0016405"},{"relation_name":"is_a","term_name":"acid-thiol ligase activity","termid":"GO:0016878"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016874","GO:0003674"],"is_obsolete":false,"name":"acetoacetate-CoA ligase activity","secondary_identifiers":["MetaCyc:ACETOACETATE--COA-LIGASE-RXN","Reactome:R-HSA-5694494","KEGG_REACTION:R01357"],"synonyms":[{"name":"acetoacetate:CoA ligase (AMP-forming)","type":"related"},{"name":"acetoacetyl-CoA synthetase activity","type":"exact"}],"termid":"GO:0030729"}


id: GO:0106346
data:
  {"annotated_genes":["SJAG_01958"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[94386],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120048"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.","definition_xrefs":["PMID:27573892"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA methyltransferase activity","termid":"GO:0008173"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01958":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140098","GO:0003824","GO:0016741","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"snRNA methyltransferase activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0106346","terms_by_termid":{"GO:0120048":null}}


id: GO:0052172
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete metabolism by symbiont of host cell wall cellulose (obsolete GO:0052172)","termid":"GO:0052172"}


id: PBO:0001922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"manganese superoxide dismutase (predicted)","termid":"PBO:0001922"}


id: PBO:0027248
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_purine-specific_mismatch_base_pair_DNA_N-glycosylase_activity","termid":"PBO:0027248"}


id: MONDO:0007752
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperheparinemia","secondary_identifiers":["MEDGEN:469019","SCTID:79674009","UMLS:C3203346","OMIM:144050","MESH:C562723","ICD9:286.5"],"synonyms":[{"name":"hyperheparinemia","type":"exact"}],"termid":"MONDO:0007752","xrefs":{"Monarch":{"xref_id":"0007752"}}}


id: GO:0060633
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.","definition_xrefs":["GOC:txnOH","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of transcription by RNA polymerase II","termid":"GO:0000122"},{"relation_name":"is_a","term_name":"regulation of transcription initiation by RNA polymerase II","termid":"GO:0060260"},{"relation_name":"is_a","term_name":"negative regulation of DNA-templated transcription initiation","termid":"GO:2000143"},{"relation_name":"negatively_regulates","term_name":"transcription initiation at RNA polymerase II promoter","termid":"GO:0006367"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"negatively_regulates","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006351","GO:0006355","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of transcription initiation by RNA polymerase II","synonyms":[{"name":"negative regulation of transcription initiation from RNA polymerase II promoter","type":"exact"}],"termid":"GO:0060633"}


id: MONDO:0015200
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infection with roundworms of the genus anisakis. Human infection results from the consumption of fish harboring roundworm larvae. The worms may cause acute nausea; vomiting; or penetrate into the wall of the digestive tract where they give rise to eosinophilic granuloma in the stomach; intestines; or the omentum.","definition_xrefs":["MESH:D017129"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Ascaridida infectious disease","termid":"MONDO:0005656"},{"relation_name":"is_a","term_name":"intestinal helminthiasis","termid":"MONDO:0024271"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"anisakiasis","secondary_identifiers":["SCTID:442652006","GARD:693","ICD9:127.1","UMLS:C0162576","MEDGEN:102418","icd11.foundation:2005274000","ICD10CM:B81.0","Orphanet:1070","NCIT:C128393","DOID:7033","EFO:0007146","MedDRA:10002533"],"synonyms":[{"name":"Anisakiases","type":"related"},{"name":"Anisakis infection","type":"related"},{"name":"Anisakis simplex infection","type":"exact"},{"name":"Pseudoterranova infection","type":"related"},{"name":"infection by Anisakis larva","type":"exact"},{"name":"infections, Anisakis simplex","type":"related"}],"termid":"MONDO:0015200","xrefs":{"Monarch":{"xref_id":"0015200"}}}


id: MOD:00559
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Other","definition_xrefs":["Unimod:208"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Unimod","termid":"MOD:00003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acrolein addition +76","synonyms":[{"name":"Acrolein addition +76","type":"related"},{"name":"Delta:H(4)C(6)","type":"related"}],"termid":"MOD:00559"}


id: PBO:0034049
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-child_nucleus_of_in_male","termid":"PBO:0034049"}


id: GO:0003168
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.","definition_xrefs":["GOC:mtg_cardiac_conduct_nov11","GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"His-Purkinje system cell differentiation","termid":"GO:0060932"},{"relation_name":"part_of","term_name":"Purkinje myocyte development","termid":"GO:0003165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"Purkinje myocyte differentiation","synonyms":[{"name":"cardiac Purkinje fiber cell differentiation","type":"exact"}],"termid":"GO:0003168"}


id: PBO:0005843
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box protein Pof7","termid":"PBO:0005843"}


id: GO:0006552
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of L-leucine, 2-amino-4-methylpentanoic acid.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-leucine metabolic process","termid":"GO:0006551"},{"relation_name":"is_a","term_name":"pyruvate family amino acid catabolic process","termid":"GO:0009080"},{"relation_name":"is_a","term_name":"branched-chain amino acid catabolic process","termid":"GO:0009083"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0006520","GO:0044281","GO:0044248"],"is_obsolete":false,"name":"L-leucine catabolic process","secondary_identifiers":["MetaCyc:LEU-DEG2-PWY"],"synonyms":[{"name":"L-leucine breakdown","type":"exact"},{"name":"L-leucine catabolism","type":"exact"},{"name":"L-leucine degradation","type":"exact"},{"name":"leucine catabolic process","type":"broad"}],"termid":"GO:0006552"}


id: GO:0120019
data:
  {"annotated_genes":["SJAG_03746"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[96747],"is_not":false,"summary":null,"term":"GO:0120019"}]},"cv_name":"molecular_function","definition":"Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.","definition_xrefs":["PMID:20823909","GOC:krc","PMID:25797198","PMID:24220498"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylcholine transporter activity","termid":"GO:0008525"},{"relation_name":"is_a","term_name":"phospholipid transfer activity","termid":"GO:0120014"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03746":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0120013"}],"interesting_parent_ids":["GO:0120013","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"phosphatidylcholine transfer activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-1483219","Reactome:R-HSA-1483087","Reactome:R-HSA-1483211"],"synonyms":[{"name":"intermembrane phosphatidylcholine transfer activity","type":"narrow"},{"name":"phosphatidylcholine carrier activity","type":"exact"}],"termid":"GO:0120019","terms_by_termid":{"GO:0120019":null}}


id: PBO:0075184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear ribonucleoprotein polypeptide F pseudogene 1","termid":"PBO:0075184"}


id: PBO:0088079
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin (Ub) chain assembly factor (E4); forms branched Ub chains on substrates destined for degradation, catalyzing K48-linked multi-monoubiquitination of K29-linked Ub chains assembled by the Ub-ligase Ufd4p; involved in the Ub-fusion degradation pathway, OLE membrane fluidity pathway, stress response survival and the ERAD pathway for misfolded proteins, where it promotes ubiquitination and transfer of ERAD substrates to Rad23p; U-box family member; homologous to human Ufd2a and Ufd2b","termid":"PBO:0088079"}


id: GO:1903787
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:bf","GOC:PARL","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biosynthetic process","termid":"GO:0009890"},{"relation_name":"is_a","term_name":"negative regulation of amide metabolic process","termid":"GO:0034249"},{"relation_name":"is_a","term_name":"negative regulation of sulfur metabolic process","termid":"GO:0051175"},{"relation_name":"is_a","term_name":"regulation of glutathione biosynthetic process","termid":"GO:1903786"},{"relation_name":"negatively_regulates","term_name":"glutathione biosynthetic process","termid":"GO:0006750"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006790"},{"rel_name":"regulates","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006790","GO:0008150"],"is_obsolete":false,"name":"negative regulation of glutathione biosynthetic process","synonyms":[{"name":"down regulation of glutathione anabolism","type":"exact"},{"name":"down regulation of glutathione biosynthesis","type":"exact"},{"name":"down regulation of glutathione biosynthetic process","type":"exact"},{"name":"down regulation of glutathione formation","type":"exact"},{"name":"down regulation of glutathione synthesis","type":"exact"},{"name":"down-regulation of glutathione anabolism","type":"exact"},{"name":"down-regulation of glutathione biosynthesis","type":"exact"},{"name":"down-regulation of glutathione biosynthetic process","type":"exact"},{"name":"down-regulation of glutathione formation","type":"exact"},{"name":"down-regulation of glutathione synthesis","type":"exact"},{"name":"downregulation of glutathione anabolism","type":"exact"},{"name":"downregulation of glutathione biosynthesis","type":"exact"},{"name":"downregulation of glutathione biosynthetic process","type":"exact"},{"name":"downregulation of glutathione formation","type":"exact"},{"name":"downregulation of glutathione synthesis","type":"exact"},{"name":"inhibition of glutathione anabolism","type":"narrow"},{"name":"inhibition of glutathione biosynthesis","type":"narrow"},{"name":"inhibition of glutathione biosynthetic process","type":"narrow"},{"name":"inhibition of glutathione formation","type":"narrow"},{"name":"inhibition of glutathione synthesis","type":"narrow"},{"name":"negative regulation of glutathione anabolism","type":"exact"},{"name":"negative regulation of glutathione biosynthesis","type":"exact"},{"name":"negative regulation of glutathione formation","type":"exact"},{"name":"negative regulation of glutathione synthesis","type":"exact"}],"termid":"GO:1903787"}


id: MONDO:0021273
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A leiomyoma that involves the ciliary body.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leiomyoma","termid":"MONDO:0001572"},{"relation_name":"is_a","term_name":"benign neoplasm of ciliary body","termid":"MONDO:0021486"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"leiomyoma of ciliary body","secondary_identifiers":["SCTID:255020006","ICD9:224.0","UMLS:C0346386","icd11.foundation:99905286","MEDGEN:138063","NCIT:C4560"],"synonyms":[{"name":"ciliary body leiomyoma","type":"exact"},{"name":"leiomyoma of the ciliary body","type":"exact"}],"termid":"MONDO:0021273","xrefs":{"Monarch":{"xref_id":"0021273"}}}


id: PBO:0085730
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck","termid":"PBO:0085730"}


id: FYPO:0000748
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mercury ions. Cells stop growing (and may die) at a concentration of mercury ions that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0002683","FYPO:0005447","FYPO:0001985","FYPO:0000003","FYPO:0000139"],"is_obsolete":false,"name":"sensitive to mercury","synonyms":[{"name":"hypersensitive to mercury","type":"exact"},{"name":"sensitive to mercury during mitotic cell cycle","type":"related"},{"name":"sensitive to mercury during vegetative growth","type":"exact"},{"name":"sensitive to mercury ions","type":"exact"}],"termid":"FYPO:0000748"}


id: MONDO:0022465
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A syndrome characterized by anotia (congenital absence of the pinna) with a normal cochlea and vestibular apparatus, with facial paralysis caused by congenital absence of the entire right facial nerve, and congenital heart disease, which may present as atrioventricular septal defects or variations of tetralogy of Fallot.","definition_xrefs":["PMID:6470867"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anotia facial palsy cardiac defect","termid":"MONDO:0022465","xrefs":{"Monarch":{"xref_id":"0022465"}}}


id: MONDO:0002486
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A spectrum of non-invasive neoplastic lesions that arise from the terminal ductal lobular units of the breast. There is atypical small epithelial cell proliferation. Pagetoid involvement of the terminal ducts may or may not be present. In the minority of cases, there is a risk for subsequent development of invasive ductal or invasive lobular carcinoma.","definition_xrefs":["NCIT:C27939"],"direct_ancestors":[{"relation_name":"is_a","term_name":"breast carcinoma in situ","termid":"MONDO:0004658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"lobular neoplasia","secondary_identifiers":["MEDGEN:167824","UMLS:C0861352","DOID:3010"],"synonyms":[{"name":"LIN","type":"exact"},{"name":"LN","type":"exact"},{"name":"lobular intraepithelial neoplasia","type":"exact"},{"name":"lobular neoplasia","type":"exact"}],"termid":"MONDO:0002486","xrefs":{"Monarch":{"xref_id":"0002486"}}}


id: GO:0019100
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The determination of sex and sexual phenotype in a male organism's germ line.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary sex determination, germ-line","termid":"GO:0007542"},{"relation_name":"is_a","term_name":"germ-line sex determination","termid":"GO:0018992"},{"relation_name":"is_a","term_name":"male sex determination","termid":"GO:0030238"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"male germ-line sex determination","termid":"GO:0019100"}


id: GO:0047010
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H+ + NADH.","definition_xrefs":["RHEA:10516","EC:1.1.1.166"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"hydroxycyclohexanecarboxylate dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R05315","MetaCyc:1.1.1.166-RXN"],"synonyms":[{"name":"(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity","type":"related"},{"name":"(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity","type":"related"},{"name":"dihydroxycyclohexanecarboxylate dehydrogenase activity","type":"related"}],"termid":"GO:0047010"}


id: GO:0051086
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.","definition_xrefs":["GOC:rb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"'de novo' post-translational protein folding","termid":"GO:0051084"},{"relation_name":"is_a","term_name":"chaperone-mediated protein folding","termid":"GO:0061077"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006457"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0051604"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006457","GO:0051604","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"chaperone mediated protein folding independent of cofactor","synonyms":[{"name":"chaperone cofactor-independent protein folding","type":"exact"}],"termid":"GO:0051086"}


id: MOD:00108
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-tyrosine residue to L-tyrosine amide.","definition_xrefs":["PubMed:1377792","PubMed:6509012","PubMed:3562898","RESID:AA0099"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C1-amidated residue","termid":"MOD:00883"},{"relation_name":"is_a","term_name":"modified L-tyrosine residue","termid":"MOD:00919"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-tyrosine amide","synonyms":[{"name":"(2S)-2-amino-3-(4-hydoxyphenyl)propanamide","type":"exact"},{"name":"L-tyrosine amide","type":"exact"},{"name":"MOD_RES Tyrosine amide","type":"exact"},{"name":"TyrN","type":"exact"},{"name":"amidated L-tyrosine","type":"exact"},{"name":"tyrosinamide","type":"exact"}],"termid":"MOD:00108"}


id: PBO:0059688
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 54","termid":"PBO:0059688"}


id: _global:has_dividend_entity
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_dividend_entity","termid":"_global:has_dividend_entity"}


id: PBO:0034617
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-delayed_onset_of_UV-damage_excision_repair","termid":"PBO:0034617"}


id: FYPO:0002553
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing is abnormal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.","definition_xrefs":["PomBase:mah","GO:0000729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal double-strand break repair during vegetative growth","termid":"FYPO:0000777"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0000293","FYPO:0000298"],"is_obsolete":false,"name":"abnormal double-strand break processing","synonyms":[{"name":"abnormal DSB processing","type":"exact"},{"name":"abnormal double-strand break processing during mitotic cell cycle","type":"related"},{"name":"abnormal double-strand break processing during vegetative growth","type":"exact"}],"termid":"FYPO:0002553"}


id: MONDO:1011332
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Mitochondrial disease that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human animal disease","termid":"MONDO:0005583"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial disease, non-human animal","termid":"MONDO:1011332","xrefs":{"Monarch":{"xref_id":"1011332"}}}


id: PBO:0052294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KH domain containing 3 like, subcortical maternal complex member","termid":"PBO:0052294"}


id: MONDO:0017608
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete dystrophic epidermolysis bullosa (obsolete MONDO:0017608)","secondary_identifiers":["NANDO:2201343"],"termid":"MONDO:0017608","xrefs":{"Monarch":{"xref_id":"0017608"}}}


id: PBO:0064634
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoribosyl pyrophosphate amidotransferase","termid":"PBO:0064634"}


id: GO:0046364
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monosaccharide metabolic process","termid":"GO:0005996"},{"relation_name":"is_a","term_name":"carbohydrate biosynthetic process","termid":"GO:0016051"},{"relation_name":"is_a","term_name":"small molecule biosynthetic process","termid":"GO:0044283"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0044281","GO:0005975","GO:0008150"],"is_obsolete":false,"name":"monosaccharide biosynthetic process","synonyms":[{"name":"monosaccharide anabolism","type":"exact"},{"name":"monosaccharide biosynthesis","type":"exact"},{"name":"monosaccharide formation","type":"exact"},{"name":"monosaccharide synthesis","type":"exact"}],"termid":"GO:0046364"}


id: PBO:0062706
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 51 subfamily F member 5 pseudogene","termid":"PBO:0062706"}


id: GO:0007626
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavior","termid":"GO:0007610"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"locomotory behavior","synonyms":[{"name":"behavior via locomotion","type":"exact"},{"name":"locomotion in response to stimulus","type":"exact"},{"name":"locomotory behavioral response to stimulus","type":"exact"},{"name":"locomotory behaviour","type":"exact"},{"name":"locomotory behavioural response to stimulus","type":"exact"}],"termid":"GO:0007626"}


id: _global:mereotopologically_related_to
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"A mereological relationship or a topological relationship","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mereotopologically_related_to","secondary_identifiers":["RO:0002323"],"termid":"_global:mereotopologically_related_to"}


id: PBO:0064775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diphosphoinositol pentakisphosphate kinase 1","termid":"PBO:0064775"}


id: MONDO:0018861
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An extremely rare mitochondrial disorder characterized by facial dysmorphism similar to that seen in Zellweger syndrome, such as frontal bossing, high forehead, upslanting palpebral fissures, hypoplastic supraorbital ridges, and epicanthal folds, and in addition, pale skin, profound hypotonia, developmental delay, and minor metabolic anomalies. No peroxysomal defects, however, have been reported. Transmission is thought to be autosomal recessive.","definition_xrefs":["Orphanet:50812"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"Zellweger-like syndrome without peroxisomal anomalies","secondary_identifiers":["MEDGEN:930773","SCTID:718880003","UMLS:C4305104","GARD:18841","icd11.foundation:697302760"],"synonyms":[{"name":"AHN-Lerman-Sagie syndrome","type":"exact"}],"termid":"MONDO:0018861","xrefs":{"Monarch":{"xref_id":"0018861"}}}


id: PBO:0053036
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LARGE1 antisense RNA 1","termid":"PBO:0053036"}


id: PR:Q9HFF2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC683.02c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9HFF2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C683.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC683.02c","synonyms":[{"name":"Spom972h-SPAC683.02c","type":"exact"}],"termid":"PR:Q9HFF2"}


id: GO:1900918
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of olefin metabolic process","termid":"GO:1900909"},{"relation_name":"is_a","term_name":"regulation of octadecene metabolic process","termid":"GO:1900917"},{"relation_name":"negatively_regulates","term_name":"octadecene metabolic process","termid":"GO:1900681"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of octadecene metabolic process","synonyms":[{"name":"down regulation of octadecene metabolic process","type":"exact"},{"name":"down regulation of octadecene metabolism","type":"related"},{"name":"down-regulation of octadecene metabolic process","type":"exact"},{"name":"down-regulation of octadecene metabolism","type":"related"},{"name":"downregulation of octadecene metabolic process","type":"exact"},{"name":"downregulation of octadecene metabolism","type":"related"},{"name":"inhibition of octadecene metabolic process","type":"narrow"},{"name":"inhibition of octadecene metabolism","type":"narrow"},{"name":"negative regulation of octadecene metabolism","type":"related"}],"termid":"GO:1900918"}


id: FYPO:0005779
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during mitosis.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to kinetochore during vegetative growth","termid":"FYPO:0002901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal protein localization to kinetochore during mitosis","synonyms":[{"name":"normal protein localisation to kinetochore during mitosis","type":"exact"},{"name":"normal protein localization to kinetochore during mitotic M phase","type":"related"},{"name":"normal protein localization to kinetochore during mitotic nuclear division","type":"related"}],"termid":"FYPO:0005779"}


id: MONDO:0054842
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any polycystic kidney disease in which the cause of the disease is a mutation in the DNAJB11 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant polycystic kidney disease","termid":"MONDO:0004691"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240","MONDO:0000426"],"is_obsolete":false,"name":"polycystic kidney disease 6 with or without polycystic liver disease","secondary_identifiers":["UMLS:C4748044","MEDGEN:1648469","DOID:0060951","OMIM:618061"],"synonyms":[{"name":"DNAJB11 polycystic kidney disease","type":"exact"},{"name":"PKD6","type":"related"},{"name":"polycystic kidney disease 6 with or without polycystic liver disease","type":"exact"},{"name":"polycystic kidney disease caused by mutation in DNAJB11","type":"exact"}],"termid":"MONDO:0054842","xrefs":{"Monarch":{"xref_id":"0054842"}}}


id: MONDO:0006563
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Seborrheic keratosis that arises from follicular structures in the skin. It presents as a solitary nodule in the skin and is characterized by the presence of prominent squamous eddies.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"seborrheic keratosis","termid":"MONDO:0008420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"inverted follicular keratosis","secondary_identifiers":["MEDGEN:87190","icd11.foundation:2109084329","Wikipedia:Inverted_follicular_keratosis","DOID:6945","SCTID:394728005","UMLS:C0334019","ICD9:264.8","EFO:1000717","NCIT:C9007"],"synonyms":[{"name":"inverted folicular keratosis","type":"exact"},{"name":"inverted follicular keratosis","type":"exact"}],"termid":"MONDO:0006563","xrefs":{"Monarch":{"xref_id":"0006563"}}}


id: SO:0001204
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region (DNA) to which Bacteriophage RNA polymerase binds, to begin transcription.","definition_xrefs":["xenbase:jb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral_promoter","termid":"SO:0002311"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Phage_RNA_Polymerase_Promoter","synonyms":[{"name":"Phage RNA Polymerase Promoter","type":"exact"}],"termid":"SO:0001204"}


id: GO:0033096
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plastid envelope","termid":"GO:0009526"},{"relation_name":"part_of","term_name":"amyloplast","termid":"GO:0009501"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"amyloplast envelope","termid":"GO:0033096"}


id: PATO:0002465
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A quality inhering in a bearer by virtue of the bearer's resembling a prism.","direct_ancestors":[{"relation_name":"is_a","term_name":"shape","termid":"PATO:0000052"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prism shaped","synonyms":[{"name":"tent shaped","type":"related"}],"termid":"PATO:0002465"}


id: GO:0120511
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: methyl (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III + oxidized [NADPH--hemoprotein reductase].","definition_xrefs":["PMID:38741075","PMID:23586995","RHEA:43728"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"methyl farnesoate epoxidase activity","secondary_identifiers":["MetaCyc:RXN-11621","EC:1.14.14.127"],"synonyms":[{"name":"CYP15A1 activity","type":"related"}],"termid":"GO:0120511"}


id: MONDO:0015575
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Rare bacterial infectious disease.","gene_count":0,"genotype_count":0,"name":"obsolete rare bacterial infectious disease (obsolete MONDO:0015575)","secondary_identifiers":["Orphanet:163582"],"synonyms":[{"name":"rare bacterial infectious disease","type":"exact"}],"termid":"MONDO:0015575","xrefs":{"Monarch":{"xref_id":"0015575"}}}


id: PBO:0005161
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"the chromatin silencing function of H2Bub is independent of H3K4 methylation","termid":"PBO:0005161"}


id: GO:1902532
data:
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id: PBO:0060872
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"negative elongation factor complex member E","termid":"PBO:0060872"}


id: FYPO:0003583
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of formation of foci containing the protein Sad1 is increased during a cellular response to DNA damage.","definition_xrefs":["PomBase:mah","PMID:24943839"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular component assembly during vegetative growth","termid":"FYPO:0001354"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"increased rate of Sad1 focus formation during response to DNA damage","synonyms":[{"name":"increased rate of Sad1 focus formation during response to DNA damage during mitotic cell cycle","type":"related"},{"name":"increased rate of Sad1 focus formation during response to DNA damage during vegetative growth","type":"exact"},{"name":"increased rate of accumulation of Sad1 foci during DNA damage response","type":"exact"}],"termid":"FYPO:0003583"}


id: PBO:0043536
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"component of oligomeric golgi complex 4","termid":"PBO:0043536"}


id: MONDO:0010313
data:
  {"annotated_genes":["SJAG_03909","SJAG_03471"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85429,85430],"is_not":false,"summary":null,"term":"MONDO:0010313"}]},"cv_name":"mondo","definition":"Any non-syndromic X-linked intellectual disability in which the cause of the disease is a mutation in the ACSL4 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03471":null,"SJAG_03909":null},"genotype_count":0,"is_obsolete":false,"name":"intellectual disability, X-linked 63","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1845672","MEDGEN:337002","MESH:C564522","DOID:0112050","GARD:5613","OMIM:300387"],"synonyms":[{"name":"ACSL4 non-syndromic X-linked intellectual disability","type":"exact"},{"name":"ACSL4-related intellectual disability","type":"related"},{"name":"MRX63","type":"related"},{"name":"intellectual developmental disorder, X-linked 63, X-linked dominant","type":"exact"},{"name":"intellectual disability, X-linked 63","type":"exact"},{"name":"intellectual disability, X-linked 68","type":"related"},{"name":"intellectual disability, X-linked type 63","type":"exact"},{"name":"mental retardation, X-linked 63","type":"related"},{"name":"mental retardation, X-linked 68","type":"related"},{"name":"mental retardation, X-linked type 63","type":"exact"},{"name":"non-syndromic X-linked intellectual disability caused by mutation in ACSL4","type":"exact"}],"termid":"MONDO:0010313","terms_by_termid":{"MONDO:0010313":null},"xrefs":{"Monarch":{"xref_id":"0010313"}}}


id: PBO:0064451
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POF1B actin binding protein","termid":"PBO:0064451"}


id: GO:1902737
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines.","definition_xrefs":["GOC:PARL","GOC:TermGenie","PMID:24464040","Wikipedia:Dendritic_filopodia","GO_REF:0000064","GOC:pad"],"direct_ancestors":[{"relation_name":"is_a","term_name":"filopodium","termid":"GO:0030175"},{"relation_name":"is_a","term_name":"neuron projection","termid":"GO:0043005"},{"relation_name":"part_of","term_name":"dendrite","termid":"GO:0030425"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"dendritic filopodium","synonyms":[{"name":"dendrite filopodium","type":"exact"}],"termid":"GO:1902737"}


id: FYPO:0001078
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in a cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal polysaccharide level","termid":"FYPO:0001077"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal beta-glucan level","synonyms":[{"name":"normal beta-D-glucan level","type":"exact"},{"name":"normal beta-glucan accumulation","type":"related"},{"name":"normal beta-glucan level during mitotic cell cycle","type":"related"},{"name":"normal beta-glucan level during vegetative growth","type":"exact"},{"name":"normal cellular beta-glucan level","type":"exact"}],"termid":"FYPO:0001078"}


id: MONDO:0016354
data:
  {"annotated_genes":["SJAG_02556","SJAG_00995","SJAG_02031","SJAG_03206"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85084],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012531"},{"annotations":[85904],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010212"},{"annotations":[85863],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010215"},{"annotations":[85814],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010216"}]},"cv_name":"mondo","definition":"Xeroderma pigmentosum/Cockayne syndrome complex (XP/CS complex) is characterized by the cutaneous features of xeroderma pigmentosum (XP) together with the systemic and neurological features of Cockayne syndrome (CS).","definition_xrefs":["Orphanet:220295"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"excluded_subClassOf","term_name":"progeroid syndrome","termid":"MONDO:0015333"},{"relation_name":"excluded_subClassOf","term_name":"premature aging syndrome","termid":"MONDO:0019303"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary photodermatosis","termid":"MONDO:0015951"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00995":null,"SJAG_02031":null,"SJAG_02556":null,"SJAG_03206":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"xeroderma pigmentosum-Cockayne syndrome complex","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C156031","UMLS:C4304411","GARD:17130","icd11.foundation:2002862606","ICD10CM:Q82.1","MEDGEN:930080"],"synonyms":[{"name":"XP/CS complex","type":"exact"}],"termid":"MONDO:0016354","terms_by_termid":{"MONDO:0010212":null,"MONDO:0010215":null,"MONDO:0010216":null,"MONDO:0012531":null},"xrefs":{"Monarch":{"xref_id":"0016354"}}}


id: MONDO:0012903
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive nonsyndromic deafness that has material basis in variation in the chromosome region 1q43-q44.","definition_xrefs":["PMID:18325041","DOID:0110502"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 45","secondary_identifiers":["GARD:22628","UMLS:C3888030","OMIM:612433","MEDGEN:854732"],"synonyms":[{"name":"DFNB45","type":"narrow"},{"name":"autosomal recessive deafness 45","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 45","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 45","type":"narrow"},{"name":"deafness, autosomal recessive 45","type":"narrow"}],"termid":"MONDO:0012903","xrefs":{"Monarch":{"xref_id":"0012903"}}}


id: MONDO:0002315
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete hereditary spastic paraplegia (obsolete MONDO:0002315)","termid":"MONDO:0002315","xrefs":{"Monarch":{"xref_id":"0002315"}}}


id: PBO:0043403
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cms1 ribosomal small subunit homolog","termid":"PBO:0043403"}


id: SO:0001309
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"2_methylthio_N6_hydroxynorvalyl_carbamoyladenosine is a modified adenosine.","direct_ancestors":[{"relation_name":"is_a","term_name":"modified_adenosine","termid":"SO:0001273"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"two_methylthio_N6_hydroxynorvalyl_carbamoyladenosine","secondary_identifiers":["RNAMOD:015"],"synonyms":[{"name":"2-methylthio-N6-hydroxynorvalyl carbamoyladenosine","type":"exact"},{"name":"ms2hn6A","type":"exact"},{"name":"two methylthio N6 hydroxynorvalyl carbamoyladenosine","type":"exact"}],"termid":"SO:0001309"}


id: PBO:0000377
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic suppressor protein Ste7","termid":"PBO:0000377"}


id: PBO:0084312
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Isopentenyl diphosphate:dimethylallyl diphosphate isomerase; catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability; isopentenyl diphosphate:dimethylallyl diphosphate isomerase is also known as IPP isomerase","termid":"PBO:0084312"}


id: GO:0120198
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the size of an imaginal disc-derived wing.","definition_xrefs":["GOC:ha","PIMD:23485686"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of imaginal disc-derived wing size","termid":"GO:0044719"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of imaginal disc-derived wing size","termid":"GO:0120198"}


id: PBO:0052457
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLF7 intronic transcript 1","termid":"PBO:0052457"}


id: PBO:0050672
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 7 (pseudogene)","termid":"PBO:0050672"}


id: FYPO:0005334
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the Holliday junctions is greater than normal. A Holliday junction is a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.","definition_xrefs":["PomBase:mah","GO:0000400","PMID:15367656"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular physical quality phenotype during vegetative growth","termid":"FYPO:0004639"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased number of Holliday junctions","synonyms":[{"name":"increased amount of X-shaped DNA","type":"related"},{"name":"increased number of Holliday junctions during mitotic cell cycle","type":"related"},{"name":"increased number of Holliday junctions during vegetative growth","type":"exact"},{"name":"increased number of four-way junctions","type":"exact"}],"termid":"FYPO:0005334"}


id: MONDO:8000002
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Discitis caused by infection with Escherichia coli.","definition_xrefs":["PMID:27070599"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial arthritis","termid":"MONDO:0004471"},{"relation_name":"is_a","term_name":"escherichia coli infection","termid":"MONDO:0020920"},{"relation_name":"is_a","term_name":"infectious discitis","termid":"MONDO:8000000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"escherichia coli discitis","termid":"MONDO:8000002","xrefs":{"Monarch":{"xref_id":"8000002"}}}


id: GO:0048330
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of axial mesodermal cell fate specification","termid":"GO:0048328"},{"relation_name":"is_a","term_name":"positive regulation of mesodermal cell fate specification","termid":"GO:0048337"},{"relation_name":"positively_regulates","term_name":"axial mesodermal cell fate specification","termid":"GO:0048327"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of axial mesodermal cell fate specification","synonyms":[{"name":"activation of axial mesodermal cell fate specification","type":"narrow"},{"name":"stimulation of axial mesodermal cell fate specification","type":"narrow"},{"name":"up regulation of axial mesodermal cell fate specification","type":"exact"},{"name":"up-regulation of axial mesodermal cell fate specification","type":"exact"},{"name":"upregulation of axial mesodermal cell fate specification","type":"exact"}],"termid":"GO:0048330"}


id: MONDO:0011968
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive limb-girdle muscular dystrophy type 2D (LGMD2D) is a subtype of autosomal recessive limb-girdle muscular dystrophy characterized by childhood onset of progressive proximal weakness of the shoulder and pelvic girdle muscles, resulting in difficulty walking, scapular winging, calf hypertrophy and contractures of the Achilles tendon, which lead to a tiptoe gait pattern. Cardiac and respiratory involvement is rare.","definition_xrefs":["Orphanet:62"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive limb-girdle muscular dystrophy","termid":"MONDO:0015152"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of alpha-sarcoglycan","termid":"MONDO:0016141"},{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0006025","MONDO:0005267"],"is_obsolete":false,"name":"autosomal recessive limb-girdle muscular dystrophy type 2D","secondary_identifiers":["SCTID:715340002","GARD:438","NCIT:C142081","DOID:0110278","MEDGEN:424706","OMIM:608099","UMLS:C2936332"],"synonyms":[{"name":"Adhalinopathy, primary","type":"related"},{"name":"Alpha-sarcoglycanopathy","type":"exact"},{"name":"DMDA2","type":"exact"},{"name":"Duchenne-like autosomal recessive muscular dystrophy type 2","type":"exact"},{"name":"Duchenne-like autosomal recessive muscular dystrophy, type 2","type":"related"},{"name":"LGMD2D","type":"exact"},{"name":"SGCA autosomal recessive limb-girdle muscular dystrophy","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy caused by mutation in SGCA","type":"exact"},{"name":"limb-girdle muscular dystrophy due to alpha-sarcoglycan deficiency","type":"exact"},{"name":"limb-girdle muscular dystrophy type 2D","type":"exact"},{"name":"limb-girdle muscular dystrophy, type 2D","type":"related"},{"name":"muscular dystrophy limb-girdle with alpha-sarcoglycan","type":"related"},{"name":"muscular dystrophy, limb-girdle, autosomal recessive 3","type":"exact"},{"name":"muscular dystrophy, limb-girdle, type 2D","type":"exact"},{"name":"primary adhalinopathy","type":"exact"}],"termid":"MONDO:0011968","xrefs":{"Monarch":{"xref_id":"0011968"}}}


id: PBO:0004207
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complexed with Cdc5 protein Cwf12","termid":"PBO:0004207"}


id: MONDO:0024321
data:
  {"annotated_genes":["SJAG_04119","SJAG_04881","SJAG_03115","SJAG_02913","SJAG_03506","SJAG_03672","SJAG_05327","SJAG_06383","SJAG_04165","SJAG_02523","SJAG_03292","SJAG_04975","SJAG_05278","SJAG_00068","SJAG_00846","SJAG_00295","SJAG_02804","SJAG_01416","SJAG_03066"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84400],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010221"},{"annotations":[84659],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033364"},{"annotations":[86206],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032808"},{"annotations":[86229],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032822"},{"annotations":[84310],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0060627"},{"annotations":[84311],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0040500"},{"annotations":[85762],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0060724"},{"annotations":[85593],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0029140"},{"annotations":[84436],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012465"},{"annotations":[85550],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009398"},{"annotations":[85389],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013882"},{"annotations":[85815],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014318"},{"annotations":[86093],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014457"},{"annotations":[84996],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014780"},{"annotations":[84831],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014832"},{"annotations":[85191],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013563"},{"annotations":[86120],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010466"},{"annotations":[85186],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014165"},{"annotations":[84630],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030037"},{"annotations":[86134],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010438"},{"annotations":[85188],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014166"}]},"cv_name":"mondo","definition":"A disease that has its basis in the disruption of GPI anchor biosynthetic process.","definition_xrefs":["MONDO:patterns/basis_in_disruption_of_process"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of glycosylation","termid":"MONDO:0024322"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00068":null,"SJAG_00295":null,"SJAG_00846":null,"SJAG_01416":null,"SJAG_02523":null,"SJAG_02804":null,"SJAG_02913":null,"SJAG_03066":null,"SJAG_03115":null,"SJAG_03292":null,"SJAG_03506":null,"SJAG_03672":null,"SJAG_04119":null,"SJAG_04165":null,"SJAG_04881":null,"SJAG_04975":null,"SJAG_05278":null,"SJAG_05327":null,"SJAG_06383":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0024322","MONDO:0005066"],"is_obsolete":false,"name":"disorder of GPI anchor biosynthesis","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"GPI anchor biosynthetic process disease","type":"exact"},{"name":"GPIBD","type":"exact"},{"name":"disorder of GPI anchor biosynthetic process","type":"exact"},{"name":"glycosylphosphatidylinositol biosynthesis defect","type":"exact"}],"termid":"MONDO:0024321","terms_by_termid":{"MONDO:0009398":null,"MONDO:0010221":null,"MONDO:0010438":null,"MONDO:0010466":null,"MONDO:0012465":null,"MONDO:0013563":null,"MONDO:0013882":null,"MONDO:0014165":null,"MONDO:0014166":null,"MONDO:0014318":null,"MONDO:0014457":null,"MONDO:0014780":null,"MONDO:0014832":null,"MONDO:0029140":null,"MONDO:0030037":null,"MONDO:0032808":null,"MONDO:0032822":null,"MONDO:0033364":null,"MONDO:0040500":null,"MONDO:0060627":null,"MONDO:0060724":null},"xrefs":{"Monarch":{"xref_id":"0024321"}}}


id: MONDO:0012672
data:
  {"annotated_genes":["SJAG_04277"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86509],"is_not":false,"summary":null,"term":"MONDO:0012672"}]},"cv_name":"mondo","definition":"The presence of calculi in the gallbladder.","definition_xrefs":["NCIT:C122822"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urinary bladder disorder","termid":"MONDO:0006026"},{"relation_name":"is_a","term_name":"hereditary gallbladder disorder","termid":"MONDO:0700225"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04277":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"cholelithiasis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:3039","DOID:10211","ICD9:574","MESH:D002769","icd11.foundation:1268183934","ICD9:574.20","OMIM:611465","EFO:0004799","ICD9:574.5","SCTID:266474003","UMLS:C0008350"],"synonyms":[{"name":"GBD4","type":"related"},{"name":"gallbladder disease 4","type":"related"},{"name":"gallbladder disease type 4","type":"exact"},{"name":"gallstones","type":"broad"}],"termid":"MONDO:0012672","terms_by_termid":{"MONDO:0012672":null},"xrefs":{"Monarch":{"xref_id":"0012672"}}}


id: PBO:0060737
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase complex assembly factor 4 pseudogene 2","termid":"PBO:0060737"}


id: PBO:0050815
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydrogen voltage gated channel 1","termid":"PBO:0050815"}


id: PBO:0005435
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chaperone activator Sti1 (predicted)","termid":"PBO:0005435"}


id: PBO:0083059
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis; FOL3 has a paralog, RMA1, that arose from the whole genome duplication","termid":"PBO:0083059"}


id: PBO:0045580
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deoxyuridine triphosphatase pseudogene 2","termid":"PBO:0045580"}


id: MONDO:0957301
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 84","secondary_identifiers":["OMIM:620409","DOID:0070583","MEDGEN:1841198","UMLS:C5830562"],"termid":"MONDO:0957301","xrefs":{"Monarch":{"xref_id":"0957301"}}}


id: GO:0170014
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A complex composed of ANK1, RHCE, RHAG, SLC4A1, EPB42, GYPA, GYPB and AQP1, that functions in the stability and shape of the erythrocyte membrane in human.","definition_xrefs":["PMID:35835865"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"ankyrin-1 complex","synonyms":[{"name":"ankyrin complex","type":"exact"},{"name":"erythrocyte ankyrin-1 complex","type":"exact"}],"termid":"GO:0170014"}


id: MONDO:0019876
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"8p inverted duplication/deletion [invdupdel(8p)] syndrome is a rare chromosomal anomaly characterized clinically by mild to severe intellectual deficit, severe developmental delay (psychomotor and speech development), hypotonia with tendency to develop progressive hypertonia and severe orthopedic problems over time, minor facial anomalies and agenesis of the corpus callosum.","definition_xrefs":["Orphanet:96092"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome 8 disorder","termid":"MONDO:0700015"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"8p inverted duplication/deletion syndrome","secondary_identifiers":["UMLS:C4273676","MEDGEN:906101","GARD:19309","SCTID:718188007"],"synonyms":[{"name":"Invdupdel(8p)","type":"exact"},{"name":"inverted 8p duplication/deletion syndrome","type":"exact"}],"termid":"MONDO:0019876","xrefs":{"Monarch":{"xref_id":"0019876"}}}


id: GO:0032147
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that initiates the activity of an inactive protein kinase.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein kinase activity","termid":"GO:0045860"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"activation of protein kinase activity","synonyms":[{"name":"protein kinase activation","type":"related"}],"termid":"GO:0032147"}


id: MONDO:0016262
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive malignant smooth muscle neoplasm, arising from the uterine corpus. It is characterized by a proliferation of neoplastic spindle cells.","definition_xrefs":["NCIT:C6340"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mixed endometrial stromal and smooth muscle tumor","termid":"MONDO:0004526"},{"relation_name":"is_a","term_name":"leiomyosarcoma","termid":"MONDO:0005058"},{"relation_name":"is_a","term_name":"uterine corpus sarcoma","termid":"MONDO:0005210"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"leiomyosarcoma of the corpus uteri","secondary_identifiers":["UMLS:C0280631","DOID:5289","SCTID:447389009","EFO:1001974","GARD:20477","MEDGEN:83679","NORD:1817","ONCOTREE:ULMS","Orphanet:213625"],"synonyms":[{"name":"Uterine Leiomyosarcoma","type":"exact"},{"name":"body of uterus leiomyosarcoma","type":"exact"},{"name":"corpus uteri leiomyosarcoma","type":"exact"},{"name":"leiomyosarcoma - uterus","type":"exact"},{"name":"leiomyosarcoma of body of uterus","type":"exact"},{"name":"leiomyosarcoma of corpus uteri","type":"exact"},{"name":"leiomyosarcoma of the body of uterus","type":"exact"},{"name":"leiomyosarcoma of the corpus uteri","type":"exact"},{"name":"leiomyosarcoma of the uterine body","type":"exact"},{"name":"leiomyosarcoma of the uterine corpus","type":"exact"},{"name":"leiomyosarcoma of the uterus","type":"exact"},{"name":"leiomyosarcoma of uterine body","type":"exact"},{"name":"leiomyosarcoma of uterine corpus","type":"exact"},{"name":"leiomyosarcoma of uterus","type":"exact"},{"name":"uterine body leiomyosarcoma","type":"exact"},{"name":"uterine corpus leiomyosarcoma","type":"exact"},{"name":"uterine leiomyosarcoma","type":"related"},{"name":"uterus leiomyosarcoma","type":"related"}],"termid":"MONDO:0016262","xrefs":{"Monarch":{"xref_id":"0016262"}}}


id: PBO:0078491
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ile (anticodon AAT) 10-1","termid":"PBO:0078491"}


id: MONDO:0014344
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any congenital heart defects, multiple types in which the cause of the disease is a mutation in the NR2F2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital heart defects, multiple types","termid":"MONDO:0000119"},{"relation_name":"is_a","term_name":"familial atrioventricular septal defect","termid":"MONDO:0020290"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"congenital heart defects, multiple types, 4","secondary_identifiers":["MEDGEN:862747","OMIM:615779","UMLS:C4014310"],"synonyms":[{"name":"CHTD4","type":"related"},{"name":"NR2F2 congenital heart defects, multiple types","type":"exact"},{"name":"congenital heart defects, multiple types caused by mutation in NR2F2","type":"exact"},{"name":"congenital heart defects, multiple types, 4","type":"exact"}],"termid":"MONDO:0014344","xrefs":{"Monarch":{"xref_id":"0014344"}}}


id: PBO:0077134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TIPIN pseudogene 1","termid":"PBO:0077134"}


id: GO:0061503
data:
  {"annotated_genes":["SJAG_02084"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[91110],"is_not":false,"summary":null,"term":"GO:0061503"}]},"cv_name":"molecular_function","definition":"Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.","definition_xrefs":["GOC:dph","PMID:23242255"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a tRNA","termid":"GO:0140101"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02084":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0140098","GO:0140101","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"tRNA threonylcarbamoyladenosine dehydratase","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0061503","terms_by_termid":{"GO:0061503":null}}


id: PBO:0028153
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_level_at_centromere_outer_repeat","termid":"PBO:0028153"}


id: GO:0047594
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = CO2 + H2O + H+ + scopolamine + succinate.","definition_xrefs":["RHEA:12797","EC:1.14.20.13"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"6-beta-hydroxyhyoscyamine epoxidase activity","secondary_identifiers":["KEGG_REACTION:R03737","MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN"],"synonyms":[{"name":"(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming)","type":"related"},{"name":"6beta-hydroxyhyoscyamine epoxidase activity","type":"related"},{"name":"hydroxyhyoscyamine dioxygenase activity","type":"related"}],"termid":"GO:0047594"}


id: MONDO:0018006
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Adult-onset distal myopathy due to VCP mutation is a rare, genetic distal myopathy disorder characterized by middle age-onset of distal leg muscle weakness, atrophy in the anterior compartment resulting in foot drop, without proximal or scapular skeletal muscle weakness. Rapidly progressive dementia, Paget disease of bone and hand weakness have been reported. Muscle biopsy shows pronounced myopathic changes with rimmed vacuoles.","definition_xrefs":["Orphanet:329478"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant distal myopathy","termid":"MONDO:0016108"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0000426"],"is_obsolete":false,"name":"adult-onset distal myopathy due to VCP mutation","secondary_identifiers":["MEDGEN:1660404","UMLS:C4749506","GARD:21492"],"termid":"MONDO:0018006","xrefs":{"Monarch":{"xref_id":"0018006"}}}


id: PBO:0049887
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HERC2 pseudogene 6","termid":"PBO:0049887"}


id: MONDO:0100246
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing migraines with or without aura.","definition_xrefs":["MONDO:patterns/inherited_susceptibility"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"migraine with or without aura, susceptibility to","secondary_identifiers":["OMIMPS:157300"],"synonyms":[{"name":"migraine with or without aura, susceptibility","type":"exact"},{"name":"migraine with or without aura, susceptibility to","type":"exact"}],"termid":"MONDO:0100246","xrefs":{"Monarch":{"xref_id":"0100246"}}}


id: SO:0001489
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The status of a whole genome sequence,where annotation, and verification of coding regions has occurred.","definition_xrefs":["DOI:10.1126"],"direct_ancestors":[{"relation_name":"is_a","term_name":"whole_genome_sequence_status","termid":"SO:0001499"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_directed_improved_draft","synonyms":[{"name":"annotation directed improvement","type":"exact"}],"termid":"SO:0001489"}


id: GO:1904674
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance.","definition_xrefs":["GO_REF:0000058","GOC:BHF_miRNA","GOC:BHF","GOC:rph","GOC:TermGenie","PMID:19409607"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of stem cell population maintenance","termid":"GO:1902459"},{"relation_name":"is_a","term_name":"regulation of somatic stem cell population maintenance","termid":"GO:1904672"},{"relation_name":"positively_regulates","term_name":"somatic stem cell population maintenance","termid":"GO:0035019"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of somatic stem cell population maintenance","synonyms":[{"name":"activation of somatic stem cell population maintenance","type":"narrow"},{"name":"up regulation of somatic stem cell population maintenance","type":"exact"},{"name":"up-regulation of somatic stem cell population maintenance","type":"exact"},{"name":"upregulation of somatic stem cell population maintenance","type":"exact"}],"termid":"GO:1904674"}


id: GO:0031721
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a hemoglobin alpha chain.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hemoglobin binding","termid":"GO:0030492"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"hemoglobin alpha binding","termid":"GO:0031721"}


id: GO:0036507
data:
  {"annotated_genes":["SJAG_01858"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92742],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904380"}]},"cv_name":"biological_process","definition":"The removal of one or more mannose residues from a mannosylated protein.","definition_xrefs":["GOC:PARL","PMID:25092655","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein deglycosylation","termid":"GO:0006517"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01858":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein demannosylation","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"protein de-mannosylation","type":"exact"}],"termid":"GO:0036507","terms_by_termid":{"GO:1904380":null}}


id: PBO:0052572
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysine methyltransferase 5A","termid":"PBO:0052572"}


id: PR:Q9USI0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC794.15 gene.","definition_xrefs":["UniProtKB:Q9USI0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C794.15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC794.15","synonyms":[{"name":"Spom972h-SPCC794.15","type":"exact"}],"termid":"PR:Q9USI0"}


id: PBO:0045766
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ECI1 antisense RNA 1","termid":"PBO:0045766"}


id: GO:0046138
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes and prosthetic groups.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete coenzyme and prosthetic group biosynthetic process (obsolete GO:0046138)","synonyms":[{"name":"coenzyme and prosthetic group anabolism","type":"exact"},{"name":"coenzyme and prosthetic group biosynthesis","type":"exact"},{"name":"coenzyme and prosthetic group biosynthetic process","type":"exact"},{"name":"coenzyme and prosthetic group formation","type":"exact"},{"name":"coenzyme and prosthetic group synthesis","type":"exact"}],"termid":"GO:0046138"}


id: PBO:0028852
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_RNA_level_during_cellular_response_to_UV","termid":"PBO:0028852"}


id: GO:0031446
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.","definition_xrefs":["GOC:mah","GOC:mtg_muscle","GOC:ef","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of twitch skeletal muscle contraction","termid":"GO:0014724"},{"relation_name":"regulates","term_name":"fast-twitch skeletal muscle fiber contraction","termid":"GO:0031443"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of fast-twitch skeletal muscle fiber contraction","synonyms":[{"name":"regulation of fast-twitch skeletal muscle contraction","type":"exact"}],"termid":"GO:0031446"}


id: PR:Q9HFE7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ankyrin-2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03046"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat-containing protein P16F5.05c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBP16F5.05c","secondary_identifiers":["UniProtKB:Q9HFE7"],"synonyms":[{"name":"Spom972h-ANK2","type":"exact"}],"termid":"PR:Q9HFE7"}


id: PBO:0054484
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1884","termid":"PBO:0054484"}


id: PBO:0044606
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DDB1 and CUL4 associated factor 12","termid":"PBO:0044606"}


id: MONDO:0060629
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal recessive","secondary_identifiers":["MEDGEN:1646665","UMLS:C4693325","EFO:0009300","OMIM:617820"],"synonyms":[{"name":"NDHMSR","type":"related"},{"name":"neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal recessive","type":"exact"}],"termid":"MONDO:0060629","xrefs":{"Monarch":{"xref_id":"0060629"}}}


id: PBO:0081511
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 417","termid":"PBO:0081511"}


id: PBO:0027923
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_cellular_protein_aggregate_level","termid":"PBO:0027923"}


id: PBO:0075667
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine palmitoyltransferase long chain base subunit 1 pseudogene 2","termid":"PBO:0075667"}


id: MOD:00484
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Chemical derivative","definition_xrefs":["Unimod:112#K"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"},{"relation_name":"is_a","term_name":"modified L-lysine residue","termid":"MOD:00912"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oxidized lysine biotinylated with biotin-LC-hydrazide, reduced","synonyms":[{"name":"OxLysBiotinRed","type":"related"},{"name":"Oxidized lysine biotinylated with biotin-LC-hydrazide, reduced","type":"related"}],"termid":"MOD:00484"}


id: PBO:0054161
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1530","termid":"PBO:0054161"}


id: PBO:0024848
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Latrunculin Sensitive Cyclin knockout","termid":"PBO:0024848"}


id: GO:0046583
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.","definition_xrefs":["ISBN:0815340729","GOC:mtg_transport","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monoatomic cation transmembrane transporter activity","termid":"GO:0008324"},{"relation_name":"is_a","term_name":"efflux transmembrane transporter activity","termid":"GO:0015562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"monoatomic cation efflux transmembrane transporter activity","synonyms":[{"name":"cation efflux permease activity","type":"exact"},{"name":"cation efflux transmembrane transporter activity","type":"broad"}],"termid":"GO:0046583"}


id: FYPO:0005544
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abnormal.","definition_xrefs":["PomBase:mah","PMID:27082518"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to plasma membrane during vegetative growth","termid":"FYPO:0002125"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0000138","FYPO:0001985"],"is_obsolete":false,"name":"abnormal protein localization to plasma membrane at cell division site during vegetative growth","synonyms":[{"name":"abnormal protein localisation to plasma membrane at cell division site during vegetative growth","type":"exact"},{"name":"abnormal protein localization in plasma membrane at cell division site during vegetative growth","type":"exact"},{"name":"abnormal protein localization to cell division site plasma membrane during vegetative growth","type":"exact"},{"name":"abnormal protein localization to plasma membrane at cell division site during mitotic cell cycle","type":"related"},{"name":"abnormal protein localization to plasma membrane division site during vegetative growth","type":"exact"}],"termid":"FYPO:0005544"}


id: PBO:0065958
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAD23 homolog B, nucleotide excision repair protein","termid":"PBO:0065958"}


id: MONDO:0004854
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the conjunctiva in a newborn due to chemical or infectious causes. Aseptic conjunctivitis is often related to the use of prophylactic medications for infectious conjunctivitis. Septic conjunctivitis is related to perinatal exposure to microorganisms.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gonococcal conjunctivitis","termid":"MONDO:0015455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"ophthalmia neonatorum","secondary_identifiers":["DOID:9699","UMLS:C0029076","MEDGEN:14489","NCIT:C116815","SCTID:34298002","ICD9:771.6","MESH:D009878"],"synonyms":[{"name":"gonococcal conjunctivitis (neonatorum)","type":"exact"},{"name":"gonococcal ophthalmia neonatorum","type":"related"},{"name":"neonatal conjunctivitis","type":"exact"}],"termid":"MONDO:0004854","xrefs":{"Monarch":{"xref_id":"0004854"}}}


id: PBO:0082497
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Catalytic subunit of adoMet-dependent tRNA methyltransferase complex; required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain; another complex member is Trm112p","termid":"PBO:0082497"}


id: PBO:0015670
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyoxylase III Hsp3106","termid":"PBO:0015670"}


id: PBO:0045655
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"double homeobox B","termid":"PBO:0045655"}


id: PBO:0056981
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 30a","termid":"PBO:0056981"}


id: GO:0043048
data:
  {"annotated_genes":["SJAG_04231"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[116951],"is_not":false,"summary":null,"term":"GO:0043048"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid biosynthetic process","termid":"GO:0008654"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04231":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"dolichyl monophosphate biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"dolichyl monophosphate anabolism","type":"exact"},{"name":"dolichyl monophosphate biosynthesis","type":"exact"},{"name":"dolichyl monophosphate formation","type":"exact"},{"name":"dolichyl monophosphate synthesis","type":"exact"}],"termid":"GO:0043048","terms_by_termid":{"GO:0043048":null}}


id: PBO:0042348
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD83 molecule","termid":"PBO:0042348"}


id: GO:0016242
data:
  {"annotated_genes":["SJAG_02723"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[105810],"is_not":false,"summary":null,"term":"GO:0016242"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of autophagy","termid":"GO:0010507"},{"relation_name":"is_a","term_name":"regulation of macroautophagy","termid":"GO:0016241"},{"relation_name":"negatively_regulates","term_name":"macroautophagy","termid":"GO:0016236"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02723":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006914"},{"rel_name":"negatively_regulates","termid":"GO:0006914"}],"interesting_parent_ids":["GO:0008150","GO:0006914"],"is_obsolete":false,"name":"negative regulation of macroautophagy","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"down regulation of macroautophagy","type":"exact"},{"name":"down-regulation of macroautophagy","type":"exact"},{"name":"downregulation of macroautophagy","type":"exact"},{"name":"inhibition of macroautophagy","type":"narrow"},{"name":"negative regulation of starvation-induced autophagy","type":"exact"}],"termid":"GO:0016242","terms_by_termid":{"GO:0016242":null}}


id: PBO:0031188
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_phosphorylation_during_vegetative_growth","termid":"PBO:0031188"}


id: PBO:0043321
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CAP-Gly domain containing linker protein 3","termid":"PBO:0043321"}


id: PBO:0000245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TPR repeat protein","termid":"PBO:0000245"}


id: MONDO:0008706
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ackerman syndrome is characterized by pyramidal molar roots and taurodontism, associated with variable anomalies. It has been described in two generations of one family. Both parents and their six sibs had pyramidal, taurodont or fused molar roots. Some of the patients also had hypotrichosis, an abnormal upper lip, thickened and wide philtrum, and/or juvenile glaucoma. Other features included entropion of the eyelid, syndactyly and clinodactyly of the fifth fingers.","definition_xrefs":["Orphanet:2561"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"Ackerman syndrome","secondary_identifiers":["OMIM:200970","SCTID:722280000","MESH:C538170","UMLS:C1860167","MEDGEN:395426","GARD:469","icd11.foundation:1946127088"],"synonyms":[{"name":"Ackerman fused molar rooth syndrome","type":"exact"},{"name":"Ackerman syndrome","type":"exact"},{"name":"glaucoma, juvenile, with unusual upper lip and dental roots","type":"related"},{"name":"juvenile glaucoma with unusual upper lip and dental roots","type":"related"},{"name":"molar roots, pyramidal, with juvenile glaucoma and unusual upper lip","type":"related"},{"name":"pyramidal molar-glaucoma-upper abnormal lip syndrome","type":"exact"},{"name":"pyramidal molars, glaucoma, abnormal upper lip","type":"related"}],"termid":"MONDO:0008706","xrefs":{"Monarch":{"xref_id":"0008706"}}}


id: GO:1900842
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of steroid biosynthetic process","termid":"GO:0010893"},{"relation_name":"is_a","term_name":"positive regulation of small molecule metabolic process","termid":"GO:0062013"},{"relation_name":"is_a","term_name":"positive regulation of secondary metabolite biosynthetic process","termid":"GO:1900378"},{"relation_name":"is_a","term_name":"regulation of helvolic acid biosynthetic process","termid":"GO:1900840"},{"relation_name":"positively_regulates","term_name":"helvolic acid biosynthetic process","termid":"GO:1900812"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"positively_regulates","termid":"GO:0019748"},{"rel_name":"positively_regulates","termid":"GO:0006629"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0019748","GO:0044281","GO:0006629"],"is_obsolete":false,"name":"positive regulation of helvolic acid biosynthetic process","synonyms":[{"name":"up regulation of helvolic acid biosynthetic process","type":"exact"},{"name":"up-regulation of helvolic acid biosynthetic process","type":"exact"},{"name":"upregulation of helvolic acid biosynthetic process","type":"exact"}],"termid":"GO:1900842"}


id: PBO:0045339
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dedicator of cytokinesis 11 pseudogene 1","termid":"PBO:0045339"}


id: FYPO:0008165
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during prometaphase of mitosis.","direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to kinetochore during mitotic M phase","termid":"FYPO:0005215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0001320","FYPO:0000138"],"is_obsolete":false,"name":"decreased protein localization to kinetochore during mitotic prometaphase","termid":"FYPO:0008165"}


id: PBO:0000206
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deletion mutant expression profiling","termid":"PBO:0000206"}


id: PBO:0049866
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"helicase, POLQ like","termid":"PBO:0049866"}


id: PR:Q09905
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is encoded by the Schizosaccharomyces pombe 972h- aps3 gene.","definition_xrefs":["PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AP-3 complex subunit sigma (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC30D11.05","secondary_identifiers":["UniProtKB:Q09905"],"synonyms":[{"name":"AP-3 complex sigma3A subunit (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-aps3","type":"exact"},{"name":"adaptor-related protein complex 3 subunit sigma (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"clathrin-associated/assembly/adaptor protein, small 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"sigma-adaptin 3A (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"sigma3-adaptin (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q09905"}


id: FYPO:0006398
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to leucine starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein phosphorylation during vegetative growth","termid":"FYPO:0002033"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0002494","FYPO:0001320","FYPO:0002274","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"abolished protein phosphorylation during cellular response to leucine starvation","synonyms":[{"name":"abolished protein phosphorylation during cellular response to leucine starvation during mitotic cell cycle","type":"related"},{"name":"abolished protein phosphorylation during cellular response to leucine starvation during vegetative growth","type":"exact"},{"name":"protein phosphorylation abolished during cellular response to leucine starvation","type":"exact"}],"termid":"FYPO:0006398"}


id: PBO:0034401
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-dependent_on_(obsolete_dependent_on)","termid":"PBO:0034401"}


id: PBO:0080003
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin specific peptidase 12","termid":"PBO:0080003"}


id: MONDO:0008891
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A progressive motor neuron disorder characterized by respiratory insufficiency, sensorineural deafness and progressive ponto-bulbar palsy.","definition_xrefs":["Orphanet:97229"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete bulbospinal muscular atrophy of childhood (obsolete MONDO:0016114)","termid":"MONDO:0016114"},{"relation_name":"excluded_subClassOf","term_name":"obsolete syndromic genetic hearing loss (obsolete MONDO:0019589)","termid":"MONDO:0019589"},{"relation_name":"is_a","term_name":"hereditary motor neuron disease","termid":"MONDO:0024257"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"riboflavin transporter deficiency","secondary_identifiers":["NORD:1960","OMIMPS:211530","UMLS:C4551777","MEDGEN:1634394","DOID:0050694","GARD:9993","MESH:C537111","SCTID:699866005"],"synonyms":[{"name":"BVVLS","type":"related"},{"name":"BVVLS1","type":"related"},{"name":"Brown-Vialetto-Van Laere syndrome 1","type":"narrow"},{"name":"Brown-Vialetto-van Laere syndrome","type":"exact"},{"name":"Fazio-Londe syndrome","type":"exact"},{"name":"disorder of riboflavin transmembrane transporter activity","type":"exact"},{"name":"pontobulbar palsy and neurosensory deafness","type":"related"},{"name":"progressive bulbar palsy with sensorineural deafness","type":"related"},{"name":"riboflavin transmembrane transporter activity disease","type":"exact"},{"name":"sensorineural hearing loss-pontobulbar palsy syndrome","type":"exact"}],"termid":"MONDO:0008891","xrefs":{"Monarch":{"xref_id":"0008891"}}}


id: PBO:0075759
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/arginine repetitive matrix 1 pseudogene 1","termid":"PBO:0075759"}


id: PBO:0084161
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Highly-acidic RWD domain-containing cytoplasmic protein; forms a highly conserved complex with Rbg2p that is responsible for efficient cell growth under amino acid starvation and binds translational activator Gcn1p in dose-dependent manner according to stress level; associates with translating ribosomes; intrinsically unstructured protein whose stability is enhanced upon binding Rbg2p","termid":"PBO:0084161"}


id: PBO:0002066
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"siepin homolog","termid":"PBO:0002066"}


id: MONDO:0958241
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cardiomyopathy, familial hypertrophic, 30, atrial","secondary_identifiers":["OMIM:620734"],"termid":"MONDO:0958241","xrefs":{"Monarch":{"xref_id":"0958241"}}}


id: PBO:0048183
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRB2 associated binding protein family member 4","termid":"PBO:0048183"}


id: PBO:0041104
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bassoon presynaptic cytomatrix protein","termid":"PBO:0041104"}


id: PBO:0111881
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PINc domain","termid":"PBO:0111881"}


id: PBO:0079731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBTF like 8 (pseudogene)","termid":"PBO:0079731"}


id: GO:0032590
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The portion of the plasma membrane surrounding a dendrite.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron projection membrane","termid":"GO:0032589"},{"relation_name":"part_of","term_name":"dendrite","termid":"GO:0030425"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"dendrite membrane","termid":"GO:0032590"}


id: PBO:0077999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TNF receptor associated factor 3","termid":"PBO:0077999"}


id: MONDO:0012276
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Generalized epilepsy-paroxysmal dyskinesia syndrome is characterized by the association of paroxysmal dyskinesia and generalized epilepsy (usually absence or generalized tonic-clonic seizures) in the same individual or family. The prevalence is unknown. Analysis in one of the reported families led to the identification of a causative mutation in the KCNMA1 gene (chromosome 10q22), encoding the alpha subunit of the BK channel. Transmission is autosomal dominant.","definition_xrefs":["Orphanet:79137"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial partial epilepsy","termid":"MONDO:0017704"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"generalized epilepsy-paroxysmal dyskinesia syndrome","secondary_identifiers":["OMIM:609446","UMLS:C5574945","DOID:0070442","GARD:16704","MEDGEN:1801137","MESH:C563719"],"synonyms":[{"name":"GEPD","type":"exact"},{"name":"PNKD3","type":"related"},{"name":"epilepsy, generalized, with paroxysmal dyskinesia","type":"related"},{"name":"generalised epilepsy and paroxysmal dyskinesia","type":"related"},{"name":"generalized epilepsy and paroxysmal dyskinesia","type":"related"},{"name":"paroxysmal nonkinesigenic dyskinesia, 3, with or without generalised epilepsy","type":"related"},{"name":"paroxysmal nonkinesigenic dyskinesia, 3, with or without generalized epilepsy","type":"related"}],"termid":"MONDO:0012276","xrefs":{"Monarch":{"xref_id":"0012276"}}}


id: GO:0061075
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of neural retina development","termid":"GO:0061074"},{"relation_name":"is_a","term_name":"positive regulation of retina development in camera-type eye","termid":"GO:1902868"},{"relation_name":"positively_regulates","term_name":"neural retina development","termid":"GO:0003407"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of neural retina development","termid":"GO:0061075"}


id: GO:0006022
data:
  {"annotated_genes":["SJAG_00442","SJAG_04728","SJAG_02845","SJAG_00978","SJAG_00620","SJAG_03723","SJAG_04868","SJAG_01453"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[101964,103831,109199,87404,70387,87743,87915],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006031"},{"annotations":[100697],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006032"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.","definition_xrefs":["GOC:ai","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"macromolecule metabolic process","termid":"GO:0043170"},{"relation_name":"is_a","term_name":"carbohydrate derivative metabolic process","termid":"GO:1901135"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00442":null,"SJAG_00620":null,"SJAG_00978":null,"SJAG_01453":null,"SJAG_02845":null,"SJAG_03723":null,"SJAG_04728":null,"SJAG_04868":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"aminoglycan metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"aminoglycan metabolism","type":"exact"}],"termid":"GO:0006022","terms_by_termid":{"GO:0006031":null,"GO:0006032":null}}


id: MONDO:0005760
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete fibroepithelial neoplasm (obsolete MONDO:0005760)","termid":"MONDO:0005760","xrefs":{"Monarch":{"xref_id":"0005760"}}}


id: PBO:0083994
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p; protein abundance increases in response to DNA replication stress","termid":"PBO:0083994"}


id: MONDO:0033200
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"hearing loss, autosomal recessive 108","secondary_identifiers":["DOID:0080263","GARD:22658","MEDGEN:1627841","OMIM:617654","UMLS:C4539997"],"synonyms":[{"name":"DFNB108","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 108","type":"narrow"},{"name":"deafness, autosomal recessive 108","type":"narrow"}],"termid":"MONDO:0033200","xrefs":{"Monarch":{"xref_id":"0033200"}}}


id: GO:0097151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.","definition_xrefs":["PMID:18550748","GOC:sjp","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of nervous system process","termid":"GO:0031646"},{"relation_name":"is_a","term_name":"modulation of inhibitory postsynaptic potential","termid":"GO:0098828"},{"relation_name":"positively_regulates","term_name":"inhibitory postsynaptic potential","termid":"GO:0060080"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of inhibitory postsynaptic potential","synonyms":[{"name":"positive regulation of IPSP","type":"exact"},{"name":"positive regulation of inhibitory post-synaptic membrane potential","type":"exact"}],"termid":"GO:0097151"}


id: MONDO:0012391
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Progressive epilepsy-intellectual deficit, Finnish type (also known as Northern epilepsy) is a subtype of neuronal ceroid lipofuscinosis (NCL) characterized by seizures, progressive decline of intellectual capacities and variable loss of vision.","definition_xrefs":["Orphanet:1947"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"progressive myoclonus epilepsy","termid":"MONDO:0020074"},{"relation_name":"is_a","term_name":"neuronal ceroid lipofuscinosis 8","termid":"MONDO:0010830"},{"relation_name":"is_a","term_name":"monogenic epilepsy","termid":"MONDO:0015653"},{"relation_name":"is_a","term_name":"syndromic dyslipidemia","termid":"MONDO:0015905"},{"relation_name":"is_a","term_name":"progressive myoclonus epilepsy","termid":"MONDO:0020074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0002561","MONDO:0002039","MONDO:0002525","MONDO:0005066","MONDO:0005559","MONDO:0005027"],"is_obsolete":false,"name":"neuronal ceroid lipofuscinosis 8 northern epilepsy variant","secondary_identifiers":["ICD10CM:G40.3","OMIM:610003","Orphanet:530298","UMLS:C1864923","MEDGEN:355328","DOID:0110724","GARD:4010"],"synonyms":[{"name":"CLN8","type":"related"},{"name":"CLN8 disease, EPMR (subtype)","type":"related"},{"name":"CLN8 disease, Northern epilepsy variant","type":"exact"},{"name":"CLN8 disease, late infantile (subtype)","type":"related"},{"name":"EPMR","type":"exact"},{"name":"NCL, Northern epilepsy variant","type":"exact"},{"name":"Northern epilepsy","type":"exact"},{"name":"ceroid lipofuscinosis neuronal 8","type":"related"},{"name":"ceroid lipofuscinosis, neuronal, 8, NORTHERN epilepsy variant","type":"related"},{"name":"early onset familial encephalopathy with neuroserpin inclusion bodies","type":"exact"},{"name":"epilepsy mental deterioration Finnish type","type":"related"},{"name":"epilepsy, progressive, with intellectual disability","type":"related"},{"name":"epilepsy, progressive, with mental retardation","type":"related"},{"name":"neuronal ceroid lipofuscinosis 8","type":"related"},{"name":"neuronal ceroid lipofuscinosis, Northern epilepsy variant","type":"exact"},{"name":"northern epilepsy variant, neuronal ceroid lipofuscinosis, Northern epilepsy variant","type":"exact"},{"name":"progressive epilepsy - intellectual disability, Finnish type","type":"related"},{"name":"progressive epilepsy with intellectual disability, northern epilepsy","type":"exact"},{"name":"progressive epilepsy with mental retardation, northern epilepsy","type":"exact"},{"name":"progressive epilepsy-intellectual disability syndrome, Finnish type","type":"exact"},{"name":"progressive myoclonic epilepsy with neuroserpin inclusion bodies","type":"exact"}],"termid":"MONDO:0012391","xrefs":{"Monarch":{"xref_id":"0012391"}}}


id: MOD:01429
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that forms an adduct with a (15)N labeled compound used as a reagent.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isotope tagged reagent derivatized residue","termid":"MOD:01426"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"(15)N isotope tagged reagent","termid":"MOD:01429"}


id: PBO:0064988
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein regulator of cytokinesis 1","termid":"PBO:0064988"}


id: PBO:0027640
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-fragmented_spindle_during_meiosis_II","termid":"PBO:0027640"}


id: GO:0031261
data:
  {"annotated_genes":["SJAG_05301","SJAG_00327","SJAG_01762","SJAG_00696","SJAG_03451","SJAG_04210","SJAG_02800","SJAG_02667","SJAG_00874","SJAG_02098","SJAG_02394","SJAG_00857","SJAG_04995","SJAG_01354","SJAG_00536","SJAG_02348","SJAG_01624","SJAG_04341","SJAG_00884","SJAG_03927","SJAG_01267"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[89648,91154,93131,93748,96516,98611,105578,106398,106986,107200,109362,110523,110780,112303,112692,114234,114402],"is_not":false,"summary":null,"term":"GO:0031261"},{"annotations":[112285,92184,111038,112612],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000811"}]},"cv_name":"cellular_component","definition":"A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.","definition_xrefs":["GOC:jl","GOC:pr","PMID:15194812","PMID:17230184","GOC:hjd","GOC:bf","GOC:vw","GOC:rb","PMID:12694535"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-DNA complex","termid":"GO:0032993"},{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"},{"relation_name":"part_of","term_name":"nucleoplasm","termid":"GO:0005654"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00327":null,"SJAG_00536":null,"SJAG_00696":null,"SJAG_00857":null,"SJAG_00874":null,"SJAG_00884":null,"SJAG_01267":null,"SJAG_01354":null,"SJAG_01624":null,"SJAG_01762":null,"SJAG_02098":null,"SJAG_02348":null,"SJAG_02394":null,"SJAG_02667":null,"SJAG_02800":null,"SJAG_03451":null,"SJAG_03927":null,"SJAG_04210":null,"SJAG_04341":null,"SJAG_04995":null,"SJAG_05301":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"part_of","termid":"GO:0005654"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005654","GO:0005575","GO:0005634","GO:0032991"],"is_obsolete":false,"name":"DNA replication preinitiation complex","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"pre-IC","type":"exact"}],"termid":"GO:0031261","terms_by_termid":{"GO:0000811":null,"GO:0031261":null}}


id: PBO:0061523
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NSFL1 cofactor","termid":"PBO:0061523"}


id: PBO:0059760
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO3 pseudogene 34","termid":"PBO:0059760"}


id: PBO:0065073
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRICKLE2 antisense RNA 2","termid":"PBO:0065073"}


id: MONDO:0042983
data:
  {"annotated_genes":["SJAG_05346","SJAG_04213","SJAG_01111","SJAG_00289","SJAG_03453","SJAG_00991"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84690],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009578"},{"annotations":[86535,86536],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024517"},{"annotations":[86355],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008612"},{"annotations":[85689,85690],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013199"}]},"cv_name":"mondo","definition":"A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.","definition_xrefs":["MESH:D020752"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"},{"relation_name":"is_a","term_name":"nervous system disorder","termid":"MONDO:0005071"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00289":null,"SJAG_00991":null,"SJAG_01111":null,"SJAG_03453":null,"SJAG_04213":null,"SJAG_05346":null},"genotype_count":0,"is_obsolete":false,"name":"neurocutaneous syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NANDO:2100220","NCIT:C84348","MEDGEN:82706","UMLS:C0265316","SCTID:78572006"],"synonyms":[{"name":"Phacomatoses","type":"related"},{"name":"Phacomatosis","type":"related"},{"name":"Phakomatoses","type":"related"},{"name":"neurocutaneous disorder","type":"related"},{"name":"neurocutaneous disorders","type":"related"},{"name":"neurocutaneous syndrome","type":"exact"},{"name":"neuroectodermal dysplasia","type":"related"},{"name":"neuroectodermal dysplasia syndrome","type":"related"},{"name":"neuroectodermal dysplasia syndromes","type":"related"},{"name":"phakomatosis","type":"related"},{"name":"syndrome, neurocutaneous","type":"related"},{"name":"syndrome, neuroectodermal dysplasia","type":"related"},{"name":"syndromes, neurocutaneous","type":"related"},{"name":"syndromes, neuroectodermal dysplasia","type":"related"}],"termid":"MONDO:0042983","terms_by_termid":{"MONDO:0008612":null,"MONDO:0009578":null,"MONDO:0013199":null,"MONDO:0024517":null},"xrefs":{"Monarch":{"xref_id":"0042983"}}}


id: PBO:0064901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 3 catalytic subunit alpha","termid":"PBO:0064901"}


id: PBO:0044285
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome X open reading frame 49","termid":"PBO:0044285"}


id: FYPO:0002109
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a cell is inviable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"tapered cell","termid":"FYPO:0000014"},{"relation_name":"has_part","term_name":"inviable cell","termid":"FYPO:0000049"},{"relation_name":"is_a","term_name":"inviable cell","termid":"FYPO:0000049"},{"relation_name":"is_a","term_name":"tapered vegetative cell","termid":"FYPO:0001119"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000004"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000004","FYPO:0000002","FYPO:0001320","FYPO:0000005"],"is_obsolete":false,"name":"inviable tapered cell","synonyms":[{"name":"inviable bottle-shaped cell","type":"exact"},{"name":"inviable bottle/skittle cell","type":"exact"},{"name":"lethal; tapered cell","type":"exact"},{"name":"skittle-inviable shaped cell","type":"exact"}],"termid":"FYPO:0002109"}


id: PBO:0042282
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD1b molecule","termid":"PBO:0042282"}


id: PBO:0063787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PHD finger protein 12","termid":"PBO:0063787"}


id: GO:2001311
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.","definition_xrefs":["GOC:mw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycerophospholipid metabolic process","termid":"GO:0006650"},{"relation_name":"is_a","term_name":"alditol phosphate metabolic process","termid":"GO:0052646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"lysobisphosphatidic acid metabolic process","synonyms":[{"name":"LBPA metabolic process","type":"exact"},{"name":"LBPA metabolism","type":"exact"},{"name":"bis(monoacylglycerol) hydrogen phosphate (BMP) metabolic process","type":"exact"},{"name":"bis(monoacylglycerol) hydrogen phosphate (BMP) metabolism","type":"exact"},{"name":"bis(monoacylglycerol) hydrogen phosphate metabolic process","type":"exact"},{"name":"bis(monoacylglycerol) hydrogen phosphate metabolism","type":"exact"},{"name":"lysobisphosphatidic acid metabolism","type":"exact"}],"termid":"GO:2001311"}


id: MONDO:0008867
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, biliary tract disease characterized by progressive obliterative cholangiopathy of the intra- and extrahepatic bile ducts, occurring in the embryonic/ perinatal period, leading to severe and persistent neonatal jaundice and acholic stool.","definition_xrefs":["Orphanet:30391"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cholestasis","termid":"MONDO:0001751"},{"relation_name":"is_a","term_name":"non-neoplastic bile duct disorder","termid":"MONDO:0006322"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004335"],"is_obsolete":false,"name":"biliary atresia","secondary_identifiers":["ICD9:751.61","icd11.foundation:645741117","MedDRA:10003650","MESH:D001656","MEDGEN:14117","DOID:13608","NANDO:1200913","NCIT:C34421","GARD:12010","SCTID:77480004","UMLS:C0005411","NANDO:2200930","NORD:1114"],"synonyms":[{"name":"atresia of bile duct","type":"exact"},{"name":"atresia of bile ducts","type":"exact"},{"name":"biliary atresia, congenital","type":"exact"},{"name":"congenital biliary atresia","type":"exact"},{"name":"isolated atresia of bile ducts","type":"exact"},{"name":"isolated biliary atresia","type":"related"},{"name":"non-syndromic biliary atresia","type":"exact"}],"termid":"MONDO:0008867","xrefs":{"Monarch":{"xref_id":"0008867"}}}


id: GO:0047814
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.","definition_xrefs":["EC:2.7.1.54","RHEA:24588"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016301","GO:0016740","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"D-arabinokinase activity","secondary_identifiers":["KEGG_REACTION:R01573","MetaCyc:D-ARABINOKINASE-RXN"],"synonyms":[{"name":"ATP:D-arabinose 5-phosphotransferase activity","type":"related"},{"name":"D-arabinokinase (phosphorylating)","type":"related"}],"termid":"GO:0047814"}


id: MONDO:0009427
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Infantile hypophosphatasia (I-HPP) is a very rare, severe form of hypophosphatasia characterized by infantile rickets without elevated serum alkaline phosphatase (ALP) activity and a wide range of clinical manifestations due to hypomineralization.","definition_xrefs":["Orphanet:247651"],"gene_count":0,"genotype_count":0,"name":"obsolete infantile hypophosphatasia (obsolete MONDO:0009427)","secondary_identifiers":["ICD10CM:E83.3","DOID:0110914","OMIM:241500","SCTID:55236002"],"synonyms":[{"name":"HOPS","type":"exact"},{"name":"hypophosphatasia, infantile","type":"related"},{"name":"hypophosphatasia, perinatal lethal","type":"related"},{"name":"infantile Rathburn disease","type":"exact"},{"name":"infantile phosphoethanolaminuria","type":"exact"},{"name":"obsolete infantile hypophosphatasia","type":"exact"}],"termid":"MONDO:0009427","xrefs":{"Monarch":{"xref_id":"0009427"}}}


id: PBO:0076802
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tektin 3","termid":"PBO:0076802"}


id: GO:0098897
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The lipid bilayer surrounding the spine apparatus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bounding membrane of organelle","termid":"GO:0098588"},{"relation_name":"part_of","term_name":"spine apparatus","termid":"GO:0097444"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"spine apparatus membrane","termid":"GO:0098897"}


id: GO:1903348
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of tight junction assembly.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:25050009","GOC:jz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell junction assembly","termid":"GO:1901890"},{"relation_name":"is_a","term_name":"regulation of bicellular tight junction assembly","termid":"GO:2000810"},{"relation_name":"positively_regulates","term_name":"bicellular tight junction assembly","termid":"GO:0070830"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"positive regulation of bicellular tight junction assembly","synonyms":[{"name":"activation of tight junction assembly","type":"narrow"},{"name":"activation of tight junction formation","type":"narrow"},{"name":"positive regulation of tight junction formation","type":"exact"},{"name":"up regulation of tight junction assembly","type":"exact"},{"name":"up regulation of tight junction formation","type":"exact"},{"name":"up-regulation of tight junction assembly","type":"exact"},{"name":"up-regulation of tight junction formation","type":"exact"},{"name":"upregulation of tight junction assembly","type":"exact"},{"name":"upregulation of tight junction formation","type":"exact"}],"termid":"GO:1903348"}


id: GO:2000309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of tumor necrosis factor superfamily cytokine production","termid":"GO:1903557"},{"relation_name":"is_a","term_name":"regulation of tumor necrosis factor (ligand) superfamily member 11 production","termid":"GO:2000307"},{"relation_name":"positively_regulates","term_name":"tumor necrosis factor (ligand) superfamily member 11 production","termid":"GO:0072535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of tumor necrosis factor (ligand) superfamily member 11 production","synonyms":[{"name":"positive regulation of RANKL production","type":"exact"},{"name":"positive regulation of TNFSF11 production","type":"exact"}],"termid":"GO:2000309"}


id: PBO:0114536
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DUF3818 and PXA domain conserved fungal protein, implicated in lipid metabolism/ membrane organization or vesicle-mediated transport","termid":"PBO:0114536"}


id: GO:0033387
data:
  {"annotated_genes":["SJAG_00043"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88102],"is_not":false,"summary":null,"term":"GO:0033387"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from arginine, via decarboxylation of ornithine.","definition_xrefs":["GOC:mah","MetaCyc:PWY-46"],"direct_ancestors":[{"relation_name":"is_a","term_name":"putrescine biosynthetic process from arginine","termid":"GO:0033388"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00043":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"putrescine biosynthetic process from arginine, via ornithine","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"putrescine anabolism from ornithine","type":"exact"},{"name":"putrescine biosynthesis from ornithine","type":"exact"},{"name":"putrescine biosynthetic process from ornithine","type":"exact"},{"name":"putrescine formation from ornithine","type":"exact"},{"name":"putrescine synthesis from ornithine","type":"exact"}],"termid":"GO:0033387","terms_by_termid":{"GO:0033387":null}}


id: PBO:0004254
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"m7G(5')pppN diphosphatase (predicted)","termid":"PBO:0004254"}


id: GO:0070279
data:
  {"annotated_genes":["SJAG_00830","SJAG_03312","SJAG_02972","SJAG_00495","SJAG_03306","SJAG_03914","SJAG_01766","SJAG_02791","SJAG_00097","SJAG_00714","SJAG_03861","SJAG_03102","SJAG_04145","SJAG_00582","SJAG_03055","SJAG_03671","SJAG_01019","SJAG_05230","SJAG_04149","SJAG_00673","SJAG_00186","SJAG_04178","SJAG_02205","SJAG_00937","SJAG_03434","SJAG_04678","SJAG_04988","SJAG_00432","SJAG_02305","SJAG_03961"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[65677,97550,90908,100024,87885,101489,102957,87056,109584,113068,104701,59863,98580,64096,66881,90509,98219,106042,110959,93687,102775,109653,68272,110379,117512,94974,92832,105934,91981,91420],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030170"}]},"cv_name":"molecular_function","definition":"Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitamin binding","termid":"GO:0019842"},{"relation_name":"is_a","term_name":"organic cyclic compound binding","termid":"GO:0097159"},{"relation_name":"is_a","term_name":"heterocyclic compound binding","termid":"GO:1901363"}],"gene_count":30,"genes_by_uniquename":{"SJAG_00097":null,"SJAG_00186":null,"SJAG_00432":null,"SJAG_00495":null,"SJAG_00582":null,"SJAG_00673":null,"SJAG_00714":null,"SJAG_00830":null,"SJAG_00937":null,"SJAG_01019":null,"SJAG_01766":null,"SJAG_02205":null,"SJAG_02305":null,"SJAG_02791":null,"SJAG_02972":null,"SJAG_03055":null,"SJAG_03102":null,"SJAG_03306":null,"SJAG_03312":null,"SJAG_03434":null,"SJAG_03671":null,"SJAG_03861":null,"SJAG_03914":null,"SJAG_03961":null,"SJAG_04145":null,"SJAG_04149":null,"SJAG_04178":null,"SJAG_04678":null,"SJAG_04988":null,"SJAG_05230":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"vitamin B6 binding","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000107":null},"termid":"GO:0070279","terms_by_termid":{"GO:0030170":null}}


id: PR:O42930
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- vps10 gene.","definition_xrefs":["UniProtKB:O42930","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar protein sorting/targeting protein 10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16C6.06","synonyms":[{"name":"CPY receptor (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-vps10","type":"exact"},{"name":"carboxypeptidase Y receptor (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"sortilin vps10 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"vacuolar carboxypeptidase sorting receptor vps10 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42930"}


id: PBO:0029202
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_micafungin","termid":"PBO:0029202"}


id: PBO:0027531
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_ribonuclease_activity","termid":"PBO:0027531"}


id: GO:0072730
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to organic cyclic compound","termid":"GO:0014070"},{"relation_name":"is_a","term_name":"response to lipid","termid":"GO:0033993"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to papulacandin B","termid":"GO:0072730"}


id: MONDO:0017393
data:
  {"annotated_genes":["SJAG_00156","SJAG_02165"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86148],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010477"},{"annotations":[85760],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011365"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00156":null,"SJAG_02165":null},"genotype_count":0,"is_obsolete":false,"name":"blepharophimosis - intellectual disability syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1698793","Orphanet:293642","GARD:10892","UMLS:C5229849"],"synonyms":[{"name":"BMRS","type":"exact"},{"name":"SBBYS syndrome","type":"related"},{"name":"Say Barber Biesecker Young-Simpson syndrome","type":"related"},{"name":"Young Simpson syndrome","type":"related"},{"name":"blepharophimosis intellectual disability syndromes","type":"related"},{"name":"blepharophimosis mental retardation syndromes","type":"related"},{"name":"blepharophimosis syndrome Ohdo type","type":"related"}],"termid":"MONDO:0017393","terms_by_termid":{"MONDO:0010477":null,"MONDO:0011365":null},"xrefs":{"Monarch":{"xref_id":"0017393"}}}


id: GO:0031606
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.","definition_xrefs":["GOC:mtg_sensu","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteasome core complex, alpha-subunit complex","termid":"GO:0019773"},{"relation_name":"part_of","term_name":"cytosolic proteasome core complex","termid":"GO:0031603"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005829"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0005829","GO:0032991"],"is_obsolete":false,"name":"cytosolic proteasome core complex, alpha-subunit complex","termid":"GO:0031606"}


id: PBO:0065259
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline rich 23C","termid":"PBO:0065259"}


id: MONDO:0004602
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete polymyalgia rheumatica (obsolete MONDO:0004602)","termid":"MONDO:0004602","xrefs":{"Monarch":{"xref_id":"0004602"}}}


id: PR:Q9P7C5
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cwf16 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P7C5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pre-mRNA-splicing factor cwf16 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC9.13c","synonyms":[{"name":"Spom972h-cwf16","type":"exact"},{"name":"complexed with cdc5 protein 16 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P7C5"}


id: PBO:0064965
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRAME family member 18","termid":"PBO:0064965"}


id: PBO:0038544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"abhydrolase domain containing 16A, phospholipase","termid":"PBO:0038544"}


id: PBO:0033775
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_termination_of_RNA_polymerase_II_transcription_at_RTS1_barrier","termid":"PBO:0033775"}


id: PBO:0042218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin P","termid":"PBO:0042218"}


id: PBO:0005637
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.8.8","termid":"PBO:0005637"}


id: GO:0002099
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.","definition_xrefs":["GOC:hjd","ISBN:155581073X"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA wobble base modification","termid":"GO:0002097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006399"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0006399","GO:0010467"],"is_obsolete":false,"name":"tRNA wobble guanine modification","termid":"GO:0002099"}


id: MONDO:0030800
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"progressive familial intrahepatic cholestasis","termid":"MONDO:0015762"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515","MONDO:0005066"],"is_obsolete":false,"name":"cholestasis, progressive familial intrahepatic, 9","secondary_identifiers":["MEDGEN:1809292","UMLS:C5676973","OMIM:619849"],"synonyms":[{"name":"PFIC9","type":"exact"},{"name":"cholestasis, progressive familial intrahepatic, 9","type":"exact"}],"termid":"MONDO:0030800","xrefs":{"Monarch":{"xref_id":"0030800"}}}


id: PBO:0084140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"High-affinity glucose transporter; member of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose; HXT4 has a paralog, HXT7, that arose from the whole genome duplication","termid":"PBO:0084140"}


id: GO:0060708
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.","definition_xrefs":["PMID:16269175","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation involved in embryonic placenta development","termid":"GO:0060706"},{"relation_name":"part_of","term_name":"spongiotrophoblast layer development","termid":"GO:0060712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"spongiotrophoblast differentiation","synonyms":[{"name":"spongiotrophoblast cell differentiation","type":"exact"}],"termid":"GO:0060708"}


id: PBO:0044818
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 109A (pseudogene)","termid":"PBO:0044818"}


id: PBO:0049371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"general transcription factor IIIA pseudogene 1","termid":"PBO:0049371"}


id: GO:0010284
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.","definition_xrefs":["PMID:7592828","PMID:10066819"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"lariciresinol reductase activity","termid":"GO:0010284"}


id: PBO:0086917
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative zinc-cluster transcription factor; involved in utilization of iron-transporting siderophore pulcherrimin","termid":"PBO:0086917"}


id: MONDO:0000665
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Apraxia is a neurological disorder characterized by the inability to perform tasks or movements, despite having the desire and physical ability to perform them. It is caused by damage to the brain, especially the parietal lobe, and can arise from many diseases, tumors, a stroke, or traumatic brain injury. In some cases it is present from birth. There are several types of apraxia, which may occur alone or together. These include: Buccofacial or orofacial apraxia is the inability to carry out facial movements on demand. This may include licking the lips, sticking out the tongue, whistling, coughing, or winking. Ideational apraxia is the inability to carryout learned, complex tasks with multiple, sequential movements. This may include dressing, eating, and bathing. Ideomotor apraxia is the inability to perform a learned task (such as using a tool) or communicate using gestures (like waving good-bye). Limb-kinetic apraxia is the inability to make fine, precise movements with an arm or leg. This may include buttoning a shirt or tying a shoe. Verbal apraxia is difficulty coordinating mouth and speech movements. Verbal apraxia may be acquired or present from birth. Constructional apraxia is the inability to copy, draw, or construct simple figures. Oculomotor apraxia is difficulty moving the eyes on command. Treatment of apraxia may include physical, speech, or occupational therapy. If apraxia occurs as a symptom of another disorder, treatment should be directed to the underlying condition.","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"agnosia","termid":"MONDO:0005638"},{"relation_name":"is_a","term_name":"perceptual disorders","termid":"MONDO:0024417"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"apraxia","secondary_identifiers":["MESH:D001072","ICD10CM:R48.2","NCIT:C180557","UMLS:C0003635","MEDGEN:8166","DOID:0060135","icd11.foundation:986651951"],"synonyms":[{"name":"Apraxias","type":"exact"},{"name":"dyspraxia","type":"exact"}],"termid":"MONDO:0000665","xrefs":{"Monarch":{"xref_id":"0000665"}}}


id: MONDO:0009238
data:
  {"annotated_genes":["SJAG_03447"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84567],"is_not":false,"summary":null,"term":"MONDO:0009238"}]},"cv_name":"mondo","definition":"Hereditary folate malabsorption (HFM) is an inherited disorder of folate transport characterized by a systemic and central nervous system (CNS) folate deficiency manifesting as megaloblastic anemia, failure to thrive, diarrhea and/or oral mucositis, immunologic dysfunction and neurological disorders.","definition_xrefs":["Orphanet:90045"],"direct_ancestors":[{"relation_name":"is_a","term_name":"megaloblastic anemia","termid":"MONDO:0001700"},{"relation_name":"is_a","term_name":"inherited deficiency anemia","termid":"MONDO:0016624"},{"relation_name":"is_a","term_name":"disorder of folate metabolism and transport","termid":"MONDO:0017313"},{"relation_name":"is_a","term_name":"malabsorption syndrome","termid":"MONDO:0020598"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03447":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0005066","MONDO:0002280","MONDO:0005570"],"is_obsolete":false,"name":"hereditary folate malabsorption","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:12983","MESH:C562799","OMIM:229050","SCTID:62578003","UMLS:C0342705","DOID:0111678","icd11.foundation:773545237","MEDGEN:83348","NCIT:C156424","NANDO:2200592","NANDO:1200810"],"synonyms":[{"name":"congenital defect of folate absorption","type":"related"},{"name":"congenital folate malabsorption","type":"exact"},{"name":"folate malabsorption, hereditary","type":"related"},{"name":"folic acid transport defect","type":"related"}],"termid":"MONDO:0009238","terms_by_termid":{"MONDO:0009238":null},"xrefs":{"Monarch":{"xref_id":"0009238"}}}


id: PBO:0072928
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small Cajal body-specific RNA 9","termid":"PBO:0072928"}


id: GO:0070678
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.","definition_xrefs":["PMID:12914940","GOC:imk","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"preprotein binding","synonyms":[{"name":"unprocessed protein binding","type":"exact"}],"termid":"GO:0070678"}


id: GO:0141092
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency or extent of nodal signaling pathway.","definition_xrefs":["PMID:17239842"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of activin receptor signaling pathway","termid":"GO:0032927"},{"relation_name":"is_a","term_name":"regulation of nodal signaling pathway","termid":"GO:1900107"},{"relation_name":"positively_regulates","term_name":"nodal signaling pathway","termid":"GO:0038092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of nodal signaling pathway","termid":"GO:0141092"}


id: MONDO:0859689
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"benign digestive system neoplasm","termid":"MONDO:0000385"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"hepatobiliary benign neoplasm","secondary_identifiers":["DOID:3117"],"termid":"MONDO:0859689","xrefs":{"Monarch":{"xref_id":"0859689"}}}


id: PBO:0055304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2731","termid":"PBO:0055304"}


id: PBO:0064459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pogo transposable element derived with ZNF domain","termid":"PBO:0064459"}


id: PBO:0049942
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-hydroxyisobutyryl-CoA hydrolase","termid":"PBO:0049942"}


id: GO:1990611
data:
  {"annotated_genes":["SJAG_01942","SJAG_04383","SJAG_02072","SJAG_00786","SJAG_00169","SJAG_03869","SJAG_04873","SJAG_00690","SJAG_02592"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94418,102505,103139],"is_not":false,"summary":null,"term":"GO:1990611"},{"annotations":[91715,98528,114749,92011,93566,108826],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990625"}]},"cv_name":"biological_process","definition":"Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).","definition_xrefs":["PMID:16278445"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of translational initiation in response to stress","termid":"GO:0043558"},{"relation_name":"is_a","term_name":"regulation of cytoplasmic translational initiation","termid":"GO:1904688"},{"relation_name":"is_a","term_name":"regulation of cytoplasmic translation in response to stress","termid":"GO:1990497"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00169":null,"SJAG_00690":null,"SJAG_00786":null,"SJAG_01942":null,"SJAG_02072":null,"SJAG_02592":null,"SJAG_03869":null,"SJAG_04383":null,"SJAG_04873":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0002181"}],"interesting_parent_ids":["GO:0002181","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of cytoplasmic translational initiation in response to stress","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1990611","terms_by_termid":{"GO:1990611":null,"GO:1990625":null}}


id: PBO:0058993
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MTOR associated protein, LST8 homolog","termid":"PBO:0058993"}


id: PBO:0054194
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1569","termid":"PBO:0054194"}


id: MONDO:0020174
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A precancerous condition that involves the skin of eyelid.","definition_xrefs":["MONDO:patterns/location"],"gene_count":0,"genotype_count":0,"name":"obsolete precancerous lesion of palpebral epidermis (obsolete MONDO:0020174)","secondary_identifiers":["Orphanet:98583"],"synonyms":[{"name":"skin of eyelid precancerous condition","type":"exact"}],"termid":"MONDO:0020174","xrefs":{"Monarch":{"xref_id":"0020174"}}}


id: FYPO:0004320
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of DNA measured in a cell differs from normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered level of substance in cell","termid":"FYPO:0000989"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"altered DNA level","synonyms":[{"name":"abnormal DNA content","type":"exact"},{"name":"abnormal DNA level","type":"exact"},{"name":"altered DNA content","type":"exact"},{"name":"altered cellular DNA level","type":"exact"}],"termid":"FYPO:0004320"}


id: GO:1900442
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of filamentous growth of a population of unicellular organisms in response to neutral pH","termid":"GO:1900440"},{"relation_name":"is_a","term_name":"positive regulation of filamentous growth of a population of unicellular organisms in response to pH","termid":"GO:1900743"},{"relation_name":"positively_regulates","term_name":"filamentous growth of a population of unicellular organisms in response to neutral pH","termid":"GO:0036178"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH","synonyms":[{"name":"activation of filamentous growth of a population of unicellular organisms in response to neutral pH","type":"narrow"},{"name":"up regulation of filamentous growth of a population of unicellular organisms in response to neutral pH","type":"exact"},{"name":"up-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH","type":"exact"},{"name":"upregulation of filamentous growth of a population of unicellular organisms in response to neutral pH","type":"exact"}],"termid":"GO:1900442"}


id: MONDO:0044311
data:
  {"annotated_genes":["SJAG_01632","SJAG_02682","SJAG_03568"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85908,85909,85910],"is_not":false,"summary":null,"term":"MONDO:0044311"}]},"cv_name":"mondo","definition":"BTDD is an autosomal dominant disorder characterized by brachycephaly, trichomegaly, and developmental delay. Although it is caused by dysfunction of the ribosome, patients do not have anemia (summary by {2:Paolini et al., 2017}).","definition_xrefs":["OMIM:617412"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01632":null,"SJAG_02682":null,"SJAG_03568":null},"genotype_count":0,"is_obsolete":false,"name":"brachycephaly, trichomegaly, and developmental delay","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0070415","UMLS:C4479431","MEDGEN:1374289"],"synonyms":[{"name":"BTDD","type":"related"},{"name":"Macinnes syndrome","type":"related"},{"name":"brachycephaly, trichomegaly, and developmental delay","type":"exact"}],"termid":"MONDO:0044311","terms_by_termid":{"MONDO:0044311":null},"xrefs":{"Monarch":{"xref_id":"0044311"}}}


id: GO:0070765
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein.","definition_xrefs":["PMID:32616437","GOC:krc","PMID:15890777","PMID:17047368","PMID:15286082","PMID:22122073","PMID:25565961","PMID:28320827"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"},{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005886","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"gamma-secretase complex","synonyms":[{"name":"CD147-gamma-secretase complex (APH-1a, PS-1, PEN-2, NCT variant)","type":"narrow"},{"name":"PS1 complex","type":"narrow"},{"name":"PS2 complex","type":"narrow"},{"name":"gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN variant)","type":"narrow"},{"name":"gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)","type":"narrow"},{"name":"gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)","type":"narrow"},{"name":"gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)","type":"narrow"},{"name":"presenilin complex","type":"exact"}],"termid":"GO:0070765"}


id: PR:000037297
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe) that has been phosphorylated on the Thr residue in the second TQ motif by rad3, and further phosphorylated a second Thr within the activation loop by autocatalysis. Example: UniProtKB:Q09170, Thr-11/Thr-328, MOD:00047.","definition_xrefs":["PMID:19357077","PomBase:AL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe)","termid":"PR:000030002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cds1/Phos(T11,T328)","pombase_gene_id":"SPCC18B5.11c","synonyms":[{"name":"PomBase_original_PRO_term_name: serine/threonine-protein kinase cds1 phosphorylated 2 (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-CHEK2/Phos:2","type":"exact"},{"name":"cds1 T328-P","type":"related"},{"name":"cds1/Phos(T11,T328)","type":"exact"}],"termid":"PR:000037297"}


id: MONDO:0700117
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A complex movement disorder characterized by tremor, rigidity, bradykinesia, chorea, reduced facial expression, and Parkinsonism-dystonia. This disease is caused by loss of function variants in the SLC6A3 gene, which impair the dopamine transporter protein. The onset of this disease ranges from infancy to adulthood.","definition_xrefs":["PMID:28749637","PMID:21112253","PMID:24613933"],"direct_ancestors":[{"relation_name":"is_a","term_name":"movement disorder","termid":"MONDO:0005395"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC6A3-related dopamine transporter deficiency syndrome","secondary_identifiers":["DOID:0070487"],"synonyms":[{"name":"DTDS","type":"exact"},{"name":"Dopamine transporter deficiency syndrome","type":"exact"}],"termid":"MONDO:0700117","xrefs":{"Monarch":{"xref_id":"0700117"}}}


id: PBO:0088234
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin-like protein","termid":"PBO:0088234"}


id: PBO:0082361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Autophagy-specific protein; required for recruiting other ATG proteins to the pre-autophagosomal structure (PAS); interacts with Atg17p and localizas to the PAS in a manner interdependent with Atg17p and Cis1p; not conserved; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress","termid":"PBO:0082361"}


id: MONDO:0030750
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"junctional epidermolysis bullosa","termid":"MONDO:0017612"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"epidermolysis bullosa, junctional 4, intermediate","secondary_identifiers":["OMIM:619787","UMLS:C2608084","MEDGEN:382015"],"synonyms":[{"name":"JEB4","type":"exact"},{"name":"epidermolysis bullosa, generalised atrophic benign","type":"exact"},{"name":"epidermolysis bullosa, generalized atrophic benign","type":"exact"},{"name":"epidermolysis bullosa, junctional 4, intermediate","type":"exact"},{"name":"epidermolysis bullosa, junctional 4, non-herlitz IIA","type":"exact"},{"name":"epidermolysis bullosa, junctional, localisata variant","type":"exact"}],"termid":"MONDO:0030750","xrefs":{"Monarch":{"xref_id":"0030750"}}}


id: MONDO:0015127
data:
  {"annotated_genes":["SJAG_03597","SJAG_03418","SJAG_00301","SJAG_00321","SJAG_04110","SJAG_04398","SJAG_03698","SJAG_02829"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85548],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012794"},{"annotations":[86090],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008980"},{"annotations":[86176],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032787"},{"annotations":[85119,85120],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0026763"},{"annotations":[86217],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030886"},{"annotations":[84723],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009514"},{"annotations":[84432],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010961"},{"annotations":[85923],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014497"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete rare genetic hypothalamic or pituitary disease (obsolete MONDO:0015968)","termid":"MONDO:0015968"},{"relation_name":"is_a","term_name":"endocrine system disorder","termid":"MONDO:0005151"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00301":null,"SJAG_00321":null,"SJAG_02829":null,"SJAG_03418":null,"SJAG_03597":null,"SJAG_03698":null,"SJAG_04110":null,"SJAG_04398":null},"genotype_count":0,"is_obsolete":false,"name":"pituitary deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:292840069","Orphanet:101957","GARD:19801","ICD10CM:E23.0"],"termid":"MONDO:0015127","terms_by_termid":{"MONDO:0008980":null,"MONDO:0009514":null,"MONDO:0010961":null,"MONDO:0012794":null,"MONDO:0014497":null,"MONDO:0026763":null,"MONDO:0030886":null,"MONDO:0032787":null},"xrefs":{"Monarch":{"xref_id":"0015127"}}}


id: PBO:0042507
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cadherin related family member 1","termid":"PBO:0042507"}


id: GO:0102131
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxyglutaryl-[acp] methyl ester = NADPH + H+ + a 3-oxo-glutaryl-[acp] methyl ester.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity (obsolete GO:0102131)","termid":"GO:0102131"}


id: PBO:0047560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FGF13 antisense RNA 1","termid":"PBO:0047560"}


id: PBO:0041287
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C1q and TNF related 12","termid":"PBO:0041287"}


id: MONDO:0010526
data:
  {"annotated_genes":["SJAG_02949"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85829],"is_not":false,"summary":null,"term":"MONDO:0010526"}]},"cv_name":"mondo","definition":"Fabry disease (FD) is a progressive, inherited, multisystemic lysosomal storage disease characterized by specific neurological, cutaneous, renal, cardiovascular, cochleo-vestibular and cerebrovascular manifestations.","definition_xrefs":["Orphanet:324"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"excluded_subClassOf","term_name":"familial restrictive cardiomyopathy","termid":"MONDO:0016340"},{"relation_name":"excluded_subClassOf","term_name":"skin vascular disease","termid":"MONDO:0019293"},{"relation_name":"excluded_subClassOf","term_name":"obsolete syndromic lymphedema (obsolete MONDO:0019520)","termid":"MONDO:0019520"},{"relation_name":"excluded_subClassOf","term_name":"obsolete nephropathy secondary to a storage or other metabolic disease (obsolete MONDO:0019743)","termid":"MONDO:0019743"},{"relation_name":"excluded_subClassOf","term_name":"hereditary peripheral neuropathy","termid":"MONDO:0020127"},{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"sphingolipidosis","termid":"MONDO:0019255"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02949":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002561"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002525","MONDO:0002561"],"is_obsolete":false,"name":"Fabry disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:301500","SCTID:16652001","UMLS:C0002986","MEDGEN:8083","MedDRA:10016016","icd11.foundation:66996647","MESH:D000795","DOID:14499","NANDO:2200563","NCIT:C84701","NORD:1115","GARD:6400","NANDO:1200157"],"synonyms":[{"name":"Alpha-galactosidase A deficiency","type":"exact"},{"name":"Anderson-Fabry disease","type":"exact"},{"name":"FD","type":"exact"},{"name":"Fabry disease","type":"exact"},{"name":"Fabry disease, Cardiac variant","type":"related"},{"name":"Fabry's disease","type":"exact"},{"name":"Fd","type":"exact"},{"name":"Gla deficiency","type":"related"},{"name":"alpha galactosidase deficiency","type":"exact"},{"name":"angiokeratoma corporis diffusum","type":"exact"},{"name":"angiokeratoma, diffuse","type":"related"},{"name":"ceramide trihexosidase deficiency","type":"related"},{"name":"deficiency of melibiase","type":"exact"},{"name":"diffuse angiokeratoma","type":"exact"},{"name":"hereditary dystopic lipidosis","type":"related"}],"termid":"MONDO:0010526","terms_by_termid":{"MONDO:0010526":null},"xrefs":{"Monarch":{"xref_id":"0010526"}}}


id: GO:0000175
data:
  {"annotated_genes":["SJAG_04824","SJAG_06586","SJAG_04407","SJAG_04006","SJAG_04519","SJAG_03745","SJAG_04084","SJAG_00966","SJAG_01798","SJAG_00401","SJAG_04818","SJAG_04153","SJAG_03876","SJAG_00081","SJAG_01822","SJAG_01836","SJAG_00841","SJAG_04369","SJAG_03132","SJAG_02540","SJAG_02993"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[89185,91457,94822,98139,101271,102121,102851,103586,104431,106624,106941,107644,110395,114463,114793,115739,117433],"is_not":false,"summary":null,"term":"GO:0000175"},{"annotations":[113566],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008859"},{"annotations":[92606,112057,115740,106942,114798],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004535"},{"annotations":[92924],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990838"}]},"cv_name":"molecular_function","definition":"Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.","definition_xrefs":["ISBN:0198547684","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3'-5' exonuclease activity","termid":"GO:0008408"},{"relation_name":"is_a","term_name":"RNA exonuclease activity, producing 5'-phosphomonoesters","termid":"GO:0016896"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00081":null,"SJAG_00401":null,"SJAG_00841":null,"SJAG_00966":null,"SJAG_01798":null,"SJAG_01822":null,"SJAG_01836":null,"SJAG_02540":null,"SJAG_02993":null,"SJAG_03132":null,"SJAG_03745":null,"SJAG_03876":null,"SJAG_04006":null,"SJAG_04084":null,"SJAG_04153":null,"SJAG_04369":null,"SJAG_04407":null,"SJAG_04519":null,"SJAG_04818":null,"SJAG_04824":null,"SJAG_06586":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0004527"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140098","GO:0016787","GO:0003674","GO:0004527","GO:0016788","GO:0003824"],"is_obsolete":false,"name":"3'-5'-RNA exonuclease activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-9836822","Reactome:R-HSA-6791227","Reactome:R-HSA-430028","Reactome:R-HSA-6791222","Reactome:R-HSA-9694632","Reactome:R-HSA-9836585","Reactome:R-HSA-9682603","Reactome:R-HSA-9822437"],"synonyms":[{"name":"3'-5' exoribonuclease activity","type":"exact"},{"name":"3'-5'-exoribonuclease activity","type":"exact"}],"termid":"GO:0000175","terms_by_termid":{"GO:0000175":null,"GO:0004535":null,"GO:0008859":null,"GO:1990838":null}}


id: SO:0001682
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A regulatory region that is involved in the control of the process of nucleotide replication.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulatory_region","termid":"SO:0005836"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"replication_regulatory_region","synonyms":[{"name":"INSDC_feature:regulatory","type":"broad"},{"name":"INSDC_qualifier:replication_regulatory_region","type":"exact"},{"name":"replication regulatory region","type":"exact"}],"termid":"SO:0001682"}


id: PBO:0031122
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cell_population_growth_on_proline_nitrogen_source","termid":"PBO:0031122"}


id: MONDO:0007934
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Benign concentric annular macular dystrophy (BCAMD) is a progressive autosomal dominant macular dystrophy characterized by parafoveal hypopigmentation followed by a retinitis pigmentosa-like phenotype (nyctalopia and peripheral vision loss) with a bullBs eye configuration.","definition_xrefs":["Orphanet:251287"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary macular dystrophy","termid":"MONDO:0020242"},{"relation_name":"is_a","term_name":"IMPG1-related dominant retinopathy","termid":"MONDO:1040036"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0000426"],"is_obsolete":false,"name":"benign concentric annular macular dystrophy","secondary_identifiers":["GARD:9887","SCTID:719520001","OMIM:153870","UMLS:C5561925","MEDGEN:1794135","MESH:C537833","icd11.foundation:1839503243","ICD10CM:H35.5"],"synonyms":[{"name":"Mcdca","type":"related"},{"name":"macular dystrophy, benign concentric annular","type":"related"},{"name":"macular dystrophy, concentric annular","type":"related"},{"name":"maculopathy, bull's eye","type":"related"},{"name":"retinitis pigmentosa 91","type":"exact"}],"termid":"MONDO:0007934","xrefs":{"Monarch":{"xref_id":"0007934"}}}


id: PBO:0013830
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pig-T, Gpi16 (predicted)","termid":"PBO:0013830"}


id: GO:0060297
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.","definition_xrefs":["GOC:tb","GOC:BHF","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of actomyosin structure organization","termid":"GO:0110020"},{"relation_name":"is_a","term_name":"regulation of supramolecular fiber organization","termid":"GO:1902903"},{"relation_name":"regulates","term_name":"sarcomere organization","termid":"GO:0045214"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0030036"},{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007010","GO:0030036","GO:0008150"],"is_obsolete":false,"name":"regulation of sarcomere organization","synonyms":[{"name":"regulation of sarcomere organisation","type":"exact"}],"termid":"GO:0060297"}


id: PBO:0053710
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 919","termid":"PBO:0053710"}


id: PBO:0044316
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome b-245 beta chain","termid":"PBO:0044316"}


id: PBO:0011974
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thiamine diphosphokinase Tnr3/ Nudix hydrolase fusion protein","termid":"PBO:0011974"}


id: GO:0070756
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cytokine production","termid":"GO:0001819"},{"relation_name":"is_a","term_name":"regulation of interleukin-35 production","termid":"GO:0070754"},{"relation_name":"positively_regulates","term_name":"interleukin-35 production","termid":"GO:0070753"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of interleukin-35 production","secondary_identifiers":["GO:0070752"],"synonyms":[{"name":"activation of interleukin-35 production","type":"narrow"},{"name":"positive regulation of IL-35 production","type":"exact"},{"name":"positive regulation of interleukin-35 biosynthetic process","type":"narrow"},{"name":"stimulation of interleukin-35 production","type":"narrow"},{"name":"up regulation of interleukin-35 production","type":"exact"},{"name":"up-regulation of interleukin-35 production","type":"exact"},{"name":"upregulation of interleukin-35 production","type":"exact"}],"termid":"GO:0070756"}


id: FYPO:0007663
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during the second meiotic nuclear division.","definition_xrefs":["PomBase:mah","PMID:11331883"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to kinetochore during meiosis","termid":"FYPO:0004762"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"abolished protein localization to kinetochore during meiosis II","synonyms":[{"name":"abolished protein localisation to kinetochore during meiosis II","type":"exact"},{"name":"abolished protein localisation to kinetochore during second meiotic nuclear division","type":"exact"}],"termid":"FYPO:0007663"}


id: FYECO:0000322
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which bortezomib was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ bortezomib","termid":"FYECO:0000322"}


id: GO:1902288
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of defense response to oomycetes.","definition_xrefs":["GOC:TermGenie","PMID:16040633"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to biotic stimulus","termid":"GO:0002831"},{"relation_name":"is_a","term_name":"regulation of defense response","termid":"GO:0031347"},{"relation_name":"is_a","term_name":"regulation of response to external stimulus","termid":"GO:0032101"},{"relation_name":"regulates","term_name":"defense response to oomycetes","termid":"GO:0002229"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of defense response to oomycetes","termid":"GO:1902288"}


id: GO:0010066
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.","definition_xrefs":["ISBN:0471245208","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary meristem tissue development","termid":"GO:0010065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ground meristem histogenesis","termid":"GO:0010066"}


id: MONDO:1012950
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Alzheimer disease that occurs in white-tufted-ear marmoset due to a mutation in the PSEN1 gene created by genetic engineering or gene editing.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"Alzheimer disease, non-human animal","termid":"MONDO:1011443"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alzheimer disease, PSEN1-related, white-tufted-ear marmoset","secondary_identifiers":["OMIA:002493-9483"],"termid":"MONDO:1012950","xrefs":{"Monarch":{"xref_id":"1012950"}}}


id: GO:0009690
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.","definition_xrefs":["ISBN:0387969845"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amine metabolic process","termid":"GO:0009308"},{"relation_name":"is_a","term_name":"hormone metabolic process","termid":"GO:0042445"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cytokinin metabolic process","synonyms":[{"name":"cytokinin metabolism","type":"exact"}],"termid":"GO:0009690"}


id: GO:0050867
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of activation.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cellular process","termid":"GO:0048522"},{"relation_name":"is_a","term_name":"regulation of cell activation","termid":"GO:0050865"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"positively_regulates","term_name":"cell activation","termid":"GO:0001775"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of cell activation","synonyms":[{"name":"activation of cell activation","type":"narrow"},{"name":"stimulation of cell activation","type":"narrow"},{"name":"up regulation of cell activation","type":"exact"},{"name":"up-regulation of cell activation","type":"exact"},{"name":"upregulation of cell activation","type":"exact"}],"termid":"GO:0050867"}


id: MONDO:0000846
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete craniodiaphyseal dysplasia (obsolete MONDO:0000846)","termid":"MONDO:0000846","xrefs":{"Monarch":{"xref_id":"0000846"}}}


id: MONDO:0000276
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease caused by infection with Powassan virus.","definition_xrefs":["MONDO:patterns/infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Flaviviridae infectious disease","termid":"MONDO:0005763"},{"relation_name":"is_a","term_name":"viral encephalitis","termid":"MONDO:0006009"},{"relation_name":"is_a","term_name":"tick-borne infectious disease","termid":"MONDO:0025294"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Powassan encephalitis","secondary_identifiers":["SCTID:416707008","icd11.foundation:1674038791","DOID:0050179","ICD9:063.8","UMLS:C0032858","MEDGEN:18601"],"synonyms":[{"name":"Powassan virus caused disease or disorder","type":"exact"},{"name":"Powassan virus disease or disorder","type":"exact"},{"name":"Powassan virus infectious disease","type":"exact"},{"name":"encephalitis, powassan","type":"related"},{"name":"powassan encephalitis virus infection","type":"exact"}],"termid":"MONDO:0000276","xrefs":{"Monarch":{"xref_id":"0000276"}}}


id: GO:0070511
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of histone H4-K20 methylation (obsolete GO:0070511)","synonyms":[{"name":"down regulation of histone H4-K20 methylation","type":"exact"},{"name":"down-regulation of histone H4-K20 methylation","type":"exact"},{"name":"downregulation of histone H4-K20 methylation","type":"exact"},{"name":"inhibition of histone H4-K20 methylation","type":"narrow"}],"termid":"GO:0070511"}


id: PBO:0061493
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nik related kinase","termid":"PBO:0061493"}


id: PBO:0055476
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2909","termid":"PBO:0055476"}


id: GO:0018276
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.","definition_xrefs":["RESID:AA0125"],"gene_count":0,"genotype_count":0,"name":"obsolete isopeptide cross-linking via N6-glycyl-L-lysine (obsolete GO:0018276)","termid":"GO:0018276"}


id: GO:0120238
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The carbohydrate rich layer at the outermost periphery of a sperm cell.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycocalyx","termid":"GO:0030112"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"sperm glycocalyx","termid":"GO:0120238"}


id: PBO:0035694
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-causally_upstream_of,_negative_effect","termid":"PBO:0035694"}


id: MONDO:1010344
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Peters anomaly that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis, non-human animal","termid":"MONDO:1011313"},{"relation_name":"is_a","term_name":"disorder of orbital region, non-human animal","termid":"MONDO:1011315"},{"relation_name":"is_a","term_name":"disorder of visual system, non-human animal","termid":"MONDO:1011316"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Peters anomaly, non-human animal","secondary_identifiers":["OMIA:001914"],"termid":"MONDO:1010344","xrefs":{"Monarch":{"xref_id":"1010344"}}}


id: PBO:0088113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar aspartate and glutamate exporter; member of a family of seven genes (AVT1-7) related to vesicular GABA-glycine transporters; involved in compartmentalizing acidic amino acids in response to nitrogen starvation; AVT6 has a paralog, AVT5, that arose from the whole genome duplication","termid":"PBO:0088113"}


id: GO:0007318
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization","termid":"GO:0008104"},{"relation_name":"part_of","term_name":"pole plasm assembly","termid":"GO:0007315"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"pole plasm protein localization","secondary_identifiers":["GO:0048115"],"synonyms":[{"name":"establishment and maintenance of pole plasm protein localization","type":"exact"},{"name":"oocyte pole plasm protein localization","type":"exact"},{"name":"pole plasm protein localisation","type":"exact"}],"termid":"GO:0007318"}


id: MONDO:0030680
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A dilated cardiomyopathy that is characterized by refractory ventricular arrhythmias and severe heart failure and that has material basis in homozygous mutation in the BAG5 gene on chromosome 14q32.","definition_xrefs":["DOID:0081162"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cardiomyopathy, dilated, 2F","secondary_identifiers":["OMIM:619747","UMLS:C5676917","MEDGEN:1802616"],"synonyms":[{"name":"CMD2F","type":"exact"},{"name":"cardiomyopathy, dilated, 2F","type":"exact"}],"termid":"MONDO:0030680","xrefs":{"Monarch":{"xref_id":"0030680"}}}


id: MONDO:0007751
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial hypercholesterolemia","termid":"MONDO:0005439"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005066"],"is_obsolete":false,"name":"hypercholesterolemia, autosomal dominant, type B","secondary_identifiers":["SCTID:238081000","OMIM:144010","MEDGEN:309962","UMLS:C1704417","GARD:8588"],"synonyms":[{"name":"apolipoprotein B-100, familial defective","type":"related"},{"name":"apolipoprotein B-100, familial ligand-defective","type":"related"},{"name":"hypercholesterolemia, autosomal dominant, type B","type":"exact"},{"name":"hypercholesterolemia, familial, 2","type":"exact"},{"name":"hypercholesterolemia, familial, due to ligand-defective apolipoprotein B","type":"related"}],"termid":"MONDO:0007751","xrefs":{"Monarch":{"xref_id":"0007751"}}}


id: GO:0030271
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the preferential cleavage: Phe-Xaa > Tyr-Xaa > Trp-Xaa > Leu-Xaa.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete chymase activity (obsolete GO:0030271)","synonyms":[{"name":"SK protease activity","type":"related"},{"name":"chymase activity","type":"exact"},{"name":"mast cell protease I activity","type":"narrow"},{"name":"mast cell serine proteinase","type":"narrow"},{"name":"skeletal muscle (SK) protease activity","type":"narrow"},{"name":"skeletal muscle protease","type":"narrow"},{"name":"skin chymotryptic proteinase","type":"narrow"}],"termid":"GO:0030271"}


id: PBO:0046819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FA core complex associated protein 20","termid":"PBO:0046819"}


id: FYPO:0002028
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one actomyosin contractile ring.","definition_xrefs":["PomBase:mah","PMID:8834798"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin cytoskeleton during vegetative growth","termid":"FYPO:0002398"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0004803"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0004803","FYPO:0001320","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"multiple actomyosin contractile rings present","synonyms":[{"name":"actomyosin contractile rings present in greater numbers","type":"exact"},{"name":"multiple actomyosin contractile rings present during mitotic cell cycle","type":"related"},{"name":"multiple actomyosin contractile rings present during vegetative growth","type":"exact"},{"name":"multiple cytokinetic contractile rings present","type":"exact"},{"name":"multiple mitotic contractile rings present","type":"exact"}],"termid":"FYPO:0002028"}


id: PBO:0054102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1461","termid":"PBO:0054102"}


id: PBO:0091208
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-His","termid":"PBO:0091208"}


id: PBO:0041402
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 6 open reading frame 62","termid":"PBO:0041402"}


id: GO:0008804
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate.","definition_xrefs":["EC:2.7.2.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, carboxyl group as acceptor","termid":"GO:0016774"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016301","GO:0016740","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"carbamate kinase activity","secondary_identifiers":["MetaCyc:CARBAMATE-KINASE-RXN","RHEA:10152"],"synonyms":[{"name":"ATP:carbamate phosphotransferase activity","type":"related"},{"name":"CKase activity","type":"related"},{"name":"carbamoyl phosphokinase activity","type":"related"},{"name":"carbamyl phosphokinase activity","type":"related"}],"termid":"GO:0008804"}


id: SO:0002016
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant that causes the extension of 3' UTR, with regard to the reference sequence.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3_prime_UTR_variant","termid":"SO:0001624"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3_prime_UTR_elongation","synonyms":[{"name":"3 prime UTR elongation","type":"exact"}],"termid":"SO:0002016"}


id: PBO:0050733
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family D (Hsp60) member 1 pseudogene 19","termid":"PBO:0050733"}


id: PBO:0046544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group FRD member 1, envelope","termid":"PBO:0046544"}


id: GO:1990724
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.","definition_xrefs":["PMID:18777589","PMID:8262940","GOC:bhm","PMID:15476813"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein complex involved in cell-cell adhesion","termid":"GO:0098635"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"galectin complex","synonyms":[{"name":"galectin-1 complex","type":"narrow"},{"name":"galectin-2 complex","type":"narrow"}],"termid":"GO:1990724"}


id: MONDO:0004029
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete ureter small cell carcinoma (obsolete MONDO:0004029)","termid":"MONDO:0004029","xrefs":{"Monarch":{"xref_id":"0004029"}}}


id: GO:0019315
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.","definition_xrefs":["GOC:jsg","GOC:ai","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"D-allose metabolic process","termid":"GO:0019314"},{"relation_name":"is_a","term_name":"hexose biosynthetic process","termid":"GO:0019319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"D-allose biosynthetic process","synonyms":[{"name":"D-allose anabolism","type":"exact"},{"name":"D-allose biosynthesis","type":"exact"},{"name":"D-allose formation","type":"exact"},{"name":"D-allose synthesis","type":"exact"}],"termid":"GO:0019315"}


id: GO:0050541
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone.","definition_xrefs":["PMID:11278918"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor","termid":"GO:0016634"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"beta,beta-carotene-9',10'-dioxygenase activity","synonyms":[{"name":"b,b-carotene-9',10'-dioxygenase activity","type":"exact"}],"termid":"GO:0050541"}


id: MONDO:0005340
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Loss of scalp and body hair involving microscopically inflammatory patchy areas.","definition_xrefs":["MESH:D000506"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alopecia","termid":"MONDO:0004907"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alopecia areata","secondary_identifiers":["ICD9:704.01","UMLS:C0002171","icd11.foundation:65720611","MEDGEN:213","EFO:0004192","DOID:986","GARD:5782","SCTID:68225006","ICD10CM:L63"],"synonyms":[{"name":"alopecia areata","type":"exact"},{"name":"alopecia circumscripta","type":"related"},{"name":"circumscribed alopecia","type":"exact"},{"name":"patchy loss of hair","type":"related"}],"termid":"MONDO:0005340","xrefs":{"Monarch":{"xref_id":"0005340"}}}


id: MONDO:0002902
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pseudohypoparathyroidism (obsolete MONDO:0002902)","termid":"MONDO:0002902","xrefs":{"Monarch":{"xref_id":"0002902"}}}


id: PR:O60138
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- wbp4 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O60138"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C18H10.07 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC18H10.07","synonyms":[{"name":"Spom972h-wbp4","type":"exact"}],"termid":"PR:O60138"}


id: PBO:0081984
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger and SCAN domain containing 10","termid":"PBO:0081984"}


id: PBO:0070375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"roundabout guidance receptor 2","termid":"PBO:0070375"}


id: GO:0038021
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.","definition_xrefs":["GOC:bf","GOC:signaling","PMID:9102398","Wikipedia:Leptin_receptor"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine receptor activity","termid":"GO:0004896"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"leptin receptor activity","termid":"GO:0038021"}


id: MONDO:0024647
data:
  {"annotated_genes":["SJAG_02463","SJAG_01941"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85722,85721],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0020722"}]},"cv_name":"mondo","definition":"Stone(s) within the urinary tract.","definition_xrefs":["NCIT:C114688"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urinary system disorder","termid":"MONDO:0002118"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01941":null,"SJAG_02463":null},"genotype_count":0,"is_obsolete":false,"name":"urolithiasis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD10CM:N20-N23","UMLS:C0451641","SCTID:95566004","MESH:D052878","icd11.foundation:1746821938","DOID:0080653","ICD10CM:N21","MEDGEN:141536"],"synonyms":[{"name":"calculus","type":"exact"},{"name":"kidney stone","type":"broad"},{"name":"urinary stones","type":"exact"},{"name":"urolithiasis","type":"exact"}],"termid":"MONDO:0024647","terms_by_termid":{"MONDO:0020722":null},"xrefs":{"Monarch":{"xref_id":"0024647"}}}


id: PR:Q9C0V2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC576.19c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9C0V2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C576.19c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC576.19c","synonyms":[{"name":"Spom972h-SPCC576.19c","type":"exact"}],"termid":"PR:Q9C0V2"}


id: GO:0120221
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement.","definition_xrefs":["GOC:krc","PMID:26506310"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cilium movement","termid":"GO:0003352"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"maintenance of ciliary planar beating movement pattern","termid":"GO:0120221"}


id: MONDO:0012021
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"myopia","termid":"MONDO:0001384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"myopia 17, autosomal dominant","secondary_identifiers":["MEDGEN:854818","OMIM:608367","UMLS:C3888211"],"synonyms":[{"name":"MYP17","type":"exact"},{"name":"myopia 17, autosomal dominant","type":"exact"},{"name":"myopia 4","type":"related"},{"name":"myopia 4, formerly","type":"related"}],"termid":"MONDO:0012021","xrefs":{"Monarch":{"xref_id":"0012021"}}}


id: GO:1903413
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.","definition_xrefs":["GO_REF:0000071","GOC:BHF","GOC:TermGenie","PMID:21757002","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to lipid","termid":"GO:0071396"},{"relation_name":"is_a","term_name":"cellular response to organic cyclic compound","termid":"GO:0071407"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"},{"relation_name":"is_a","term_name":"response to bile acid","termid":"GO:1903412"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to bile acid","termid":"GO:1903413"}


id: PBO:0066776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 74","termid":"PBO:0066776"}


id: MONDO:0032933
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"partial duplication of the short arm of chromosome 1","termid":"MONDO:0017012"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 1p36.33 duplication syndrome, atad3 gene cluster, autosomal dominant","secondary_identifiers":["UMLS:C5394150","DOID:0070470","OMIM:618815","Orphanet:656279","MEDGEN:1708515"],"synonyms":[{"name":"CHROMOSOME 1p36.33 DUPLICATION SYNDROME, ATAD3 GENE CLUSTER, AUTOSOMAL DOMINANT","type":"related"}],"termid":"MONDO:0032933","xrefs":{"Monarch":{"xref_id":"0032933"}}}


id: PBO:0046463
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"equatorin","termid":"PBO:0046463"}


id: FYPO:0007251
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of lipid binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal lipid binding","termid":"FYPO:0007250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0001985","FYPO:0000707"],"is_obsolete":false,"name":"decreased lipid binding","synonyms":[{"name":"reduced lipid binding","type":"exact"}],"termid":"FYPO:0007251"}


id: PATO:0001860
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A coordination which is relatively low.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"coordinated","termid":"PATO:0000769"},{"relation_name":"is_a","term_name":"decreased object quality","termid":"PATO:0002303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased coordination","synonyms":[{"name":"low coordination","type":"exact"}],"termid":"PATO:0001860"}


id: GO:0005517
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. This term was not defined before being made obsolete.","definition_xrefs":["GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete calmodulin inhibitor activity (obsolete GO:0005517)","synonyms":[{"name":"calmodulin inhibitor activity","type":"exact"}],"termid":"GO:0005517"}


id: MONDO:0858989
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autosomal recessive spastic paraplegia type 84 (obsolete MONDO:0858989)","termid":"MONDO:0858989","xrefs":{"Monarch":{"xref_id":"0858989"}}}


id: PATO:0000114
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000114 temperature sensitivity (obsolete PATO:0000114)","termid":"PATO:0000114"}


id: GO:0016169
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.","definition_xrefs":["ISBN:0192800981"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacteriochlorophyll binding","termid":"GO:0042314"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"bacteriochlorophyll c binding","termid":"GO:0016169"}


id: GO:1990792
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.","definition_xrefs":["PMID:20877310"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to growth factor stimulus","termid":"GO:0071363"},{"relation_name":"is_a","term_name":"response to glial cell derived neurotrophic factor","termid":"GO:1990790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to glial cell derived neurotrophic factor","synonyms":[{"name":"cellular response to ATF","type":"exact"},{"name":"cellular response to GDNF","type":"exact"},{"name":"cellular response to astrocyte-derived trophic factor","type":"exact"}],"termid":"GO:1990792"}


id: GO:0006271
data:
  {"annotated_genes":["SJAG_01010","SJAG_02294","SJAG_00884","SJAG_00198","SJAG_02199","SJAG_04879","SJAG_00272","SJAG_05197","SJAG_01823","SJAG_03495","SJAG_02690","SJAG_00618","SJAG_05239","SJAG_02667","SJAG_02182","SJAG_02908","SJAG_00874","SJAG_04877","SJAG_03780","SJAG_04210","SJAG_05232","SJAG_01762","SJAG_02818","SJAG_00814","SJAG_04190","SJAG_04183","SJAG_00729","SJAG_00863"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[106404,114239,114410],"is_not":false,"summary":null,"term":"GO:0006271"},{"annotations":[111411,114541,88782,111651,103399,106507,104093,106141,108259,94429,93158,109098,112698,102006,94463,112288],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902983"},{"annotations":[96622],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006273"},{"annotations":[96623,109100],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006272"},{"annotations":[102008,104095,103403,117309,108261,94431],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903459"},{"annotations":[93160,103404,94432,88783,94464,106509,104096,106142],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903460"},{"annotations":[99796,99832,91762,91851,103329,100687,94253],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1903461"}]},"cv_name":"biological_process","definition":"The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication.","definition_xrefs":["GOC:mah","ISBN:071673706X","ISBN:0815316194"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA strand elongation","termid":"GO:0022616"},{"relation_name":"part_of","term_name":"DNA-templated DNA replication","termid":"GO:0006261"}],"gene_count":28,"genes_by_uniquename":{"SJAG_00198":null,"SJAG_00272":null,"SJAG_00618":null,"SJAG_00729":null,"SJAG_00814":null,"SJAG_00863":null,"SJAG_00874":null,"SJAG_00884":null,"SJAG_01010":null,"SJAG_01762":null,"SJAG_01823":null,"SJAG_02182":null,"SJAG_02199":null,"SJAG_02294":null,"SJAG_02667":null,"SJAG_02690":null,"SJAG_02818":null,"SJAG_02908":null,"SJAG_03495":null,"SJAG_03780":null,"SJAG_04183":null,"SJAG_04190":null,"SJAG_04210":null,"SJAG_04877":null,"SJAG_04879":null,"SJAG_05197":null,"SJAG_05232":null,"SJAG_05239":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006260"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0006260"],"is_obsolete":false,"name":"DNA strand elongation involved in DNA replication","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"DNA replication elongation","type":"exact"},{"name":"DNA strand elongation during DNA replication","type":"related"}],"termid":"GO:0006271","terms_by_termid":{"GO:0006271":null,"GO:0006272":null,"GO:0006273":null,"GO:1902983":null,"GO:1903459":null,"GO:1903460":null,"GO:1903461":null}}


id: GO:0032371
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lipid transport","termid":"GO:0032368"},{"relation_name":"regulates","term_name":"sterol transport","termid":"GO:0015918"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of sterol transport","termid":"GO:0032371"}


id: MONDO:0012581
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any osteogenesis imperfecta in which the cause of the disease is a mutation in the P3H1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteogenesis imperfecta and a reduction of bone mineral density.","termid":"MONDO:0800064"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"osteogenesis imperfecta type 8","secondary_identifiers":["MESH:C536049","OMIM:610915","UMLS:C1970458","GARD:10152","DOID:0110336","MEDGEN:410075"],"synonyms":[{"name":"OI type VIII","type":"related"},{"name":"OI, type 8","type":"related"},{"name":"OI8","type":"exact"},{"name":"P3H1 osteogenesis imperfecta","type":"exact"},{"name":"osteogenesis imperfecta caused by mutation in P3H1","type":"exact"},{"name":"osteogenesis imperfecta type 8","type":"exact"},{"name":"osteogenesis imperfecta type VIII","type":"exact"},{"name":"osteogenesis imperfecta, type 8","type":"related"},{"name":"osteogenesis imperfecta, type VIII","type":"related"}],"termid":"MONDO:0012581","xrefs":{"Monarch":{"xref_id":"0012581"}}}


id: GO:0061227
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pattern specification involved in kidney development","termid":"GO:0061004"},{"relation_name":"part_of","term_name":"mesonephros development","termid":"GO:0001823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pattern specification involved in mesonephros development","synonyms":[{"name":"mesonephros pattern formation","type":"related"},{"name":"mesonephros pattern specification","type":"exact"}],"termid":"GO:0061227"}


id: GO:0072749
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to organic cyclic compound","termid":"GO:0071407"},{"relation_name":"is_a","term_name":"response to cytochalasin B","termid":"GO:1901328"},{"relation_name":"is_a","term_name":"cellular response to nitrogen compound","termid":"GO:1901699"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to cytochalasin B","termid":"GO:0072749"}


id: MONDO:0022208
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"arthropathy","termid":"MONDO:0006816"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crystal arthropathy","secondary_identifiers":["SCTID:18834007","ICD9:712.90","UMLS:C0152087","ICD9:712","MEDGEN:508879","ICD9:712.80","ICD9:712.98","ICD9:712.88"],"synonyms":[{"name":"Arthritides, Crystal","type":"related"},{"name":"Arthritides, Crystalline","type":"related"},{"name":"Arthritis, Crystal","type":"related"},{"name":"Arthritis, Crystalline","type":"related"},{"name":"Arthropathies, Crystal","type":"related"},{"name":"Arthropathies, Crystalline","type":"related"},{"name":"Arthropathy, Crystal","type":"related"},{"name":"Arthropathy, Crystalline","type":"related"},{"name":"Crystal Arthritides","type":"related"},{"name":"Crystal Arthritis","type":"related"},{"name":"Crystal Arthropathies","type":"related"},{"name":"Crystal Arthropathy","type":"related"},{"name":"Crystal arthropathy","type":"related"},{"name":"Crystal-induced arthritis AND/OR synovitis","type":"related"},{"name":"Crystal-related arthropathy and periarthropathy","type":"related"},{"name":"Crystalline Arthritides","type":"related"},{"name":"Crystalline Arthritis","type":"related"},{"name":"Crystalline Arthropathies","type":"related"},{"name":"Crystalline Arthropathy","type":"related"},{"name":"Crystalline arthritis","type":"related"},{"name":"crystal arthropathy","type":"exact"},{"name":"crystal-induced arthritis and/or synovitis","type":"related"},{"name":"crystal-related arthropathy and periarthropathy","type":"related"},{"name":"crystalline arthritis","type":"related"}],"termid":"MONDO:0022208","xrefs":{"Monarch":{"xref_id":"0022208"}}}


id: PBO:0044209
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cathepsin O","termid":"PBO:0044209"}


id: PBO:0039858
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GTPase activating protein 23","termid":"PBO:0039858"}


id: MONDO:0012446
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"epidermal disease","termid":"MONDO:0019268"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"seborrhea-like dermatitis with psoriasiform elements","secondary_identifiers":["MESH:C565217","GARD:17039","MEDGEN:342832","UMLS:C1853258","OMIM:610227","Orphanet:168606"],"synonyms":[{"name":"seborrhea-like dermatitis with psoriasiform elements","type":"exact"}],"termid":"MONDO:0012446","xrefs":{"Monarch":{"xref_id":"0012446"}}}


id: PBO:0069967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1262, pseudogene","termid":"PBO:0069967"}


id: MONDO:0008816
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Arnold-Chiari malformation type II is a rare, central nervous system malformation characterized by caudal displacement of the cerebellum, pons, medulla and fourth ventricle through the foramen magnum into the spinal canal, and is typically associated with myelomeningocele. Variable other central nervous system abnormalities might be present (partial or complete agenesis of the corpus callosum, a small fourth ventricle, obstructive hydrocephalus, falx and tentorium defects, and polygyria). Symptoms include hypotonia, apnea with cyanosis, dysphagia, opisthotonus, nystagmus, spasticity, ataxia, and occipital headache.","definition_xrefs":["Orphanet:1136"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Chiari malformation","termid":"MONDO:0000115"},{"relation_name":"is_a","term_name":"spina bifida cystica","termid":"MONDO:0017069"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"Chiari malformation type II","secondary_identifiers":["UMLS:C0555206","SCTID:373587001","GARD:9232","MEDGEN:108222","OMIM:207950","MedDRA:10056945"],"synonyms":[{"name":"Arnold Chiari malformation type II","type":"related"},{"name":"Arnold-Chiari malformation","type":"related"},{"name":"Arnold-Chiari malformation type 2","type":"exact"},{"name":"Arnold-Chiari malformation type II","type":"exact"},{"name":"Chiari malformation type 2","type":"exact"},{"name":"Chiari malformation type II","type":"exact"},{"name":"Chiari type II malformation","type":"related"},{"name":"Cm2","type":"related"}],"termid":"MONDO:0008816","xrefs":{"Monarch":{"xref_id":"0008816"}}}


id: PBO:0067526
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 670, pseudogene","termid":"PBO:0067526"}


id: PR:P36603
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A ribonucleoside-diphosphate reductase small chain that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PomBase:MAH","PMID:12867051","PMID:20516199"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"},{"relation_name":"is_a","term_name":"ribonucleoside-diphosphate reductase small chain (Schizosaccharomyces pombe)","termid":"PR:000036299"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleoside-diphosphate reductase small chain (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC25D12.04","secondary_identifiers":["PR:000027714","UniProtKB:P36603"],"synonyms":[{"name":"SPBC25D12.04","type":"related"},{"name":"SUC22","type":"related"},{"name":"Spom972h-suc22","type":"exact"}],"termid":"PR:P36603"}


id: PBO:0002643
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.1.1.25","termid":"PBO:0002643"}


id: PBO:0088112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway; protein increases in abundance and relative distribution to cytoplasmic foci increases upon DNA replication stress","termid":"PBO:0088112"}


id: GO:1904216
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:25901327"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transmembrane transport","termid":"GO:0034764"},{"relation_name":"is_a","term_name":"positive regulation of protein transport","termid":"GO:0051222"},{"relation_name":"is_a","term_name":"regulation of protein import into chloroplast stroma","termid":"GO:1904215"},{"relation_name":"positively_regulates","term_name":"protein import into chloroplast stroma","termid":"GO:0045037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0055085"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"positive regulation of protein import into chloroplast stroma","synonyms":[{"name":"activation of chloroplast stroma protein import","type":"narrow"},{"name":"activation of protein import into chloroplast stroma","type":"narrow"},{"name":"activation of protein transport into chloroplast stroma","type":"narrow"},{"name":"positive regulation of chloroplast stroma protein import","type":"exact"},{"name":"positive regulation of protein transport into chloroplast stroma","type":"exact"},{"name":"up regulation of chloroplast stroma protein import","type":"exact"},{"name":"up regulation of protein import into chloroplast stroma","type":"exact"},{"name":"up regulation of protein transport into chloroplast stroma","type":"exact"},{"name":"up-regulation of chloroplast stroma protein import","type":"exact"},{"name":"up-regulation of protein import into chloroplast stroma","type":"exact"},{"name":"up-regulation of protein transport into chloroplast stroma","type":"exact"},{"name":"upregulation of chloroplast stroma protein import","type":"exact"},{"name":"upregulation of protein import into chloroplast stroma","type":"exact"},{"name":"upregulation of protein transport into chloroplast stroma","type":"exact"}],"termid":"GO:1904216"}


id: GO:0097075
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7.","definition_xrefs":["GOC:cna","PMID:18068231"],"direct_ancestors":[{"relation_name":"is_a","term_name":"interferon regulatory factor complex","termid":"GO:0097071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"interferon regulatory factor 3-interferon regulatory factor 7 complex","synonyms":[{"name":"IRF3:IRF7 complex","type":"exact"}],"termid":"GO:0097075"}


id: GO:0034950
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete phenylboronic acid monooxygenase activity (obsolete GO:0034950)","termid":"GO:0034950"}


id: PBO:0074394
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small integral membrane protein 3","termid":"PBO:0074394"}


id: PBO:0043274
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-type lectin domain family 2 member D","termid":"PBO:0043274"}


id: GO:0090018
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.","definition_xrefs":["GOC:tb","GOC:dph","GOC:sdb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"neural plate formation","termid":"GO:0021990"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"posterior neural plate formation","termid":"GO:0090018"}


id: PBO:0004514
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiosis specific cyclin Crs1","termid":"PBO:0004514"}


id: PBO:0060415
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAA50 pseudogene 2","termid":"PBO:0060415"}


id: FYPO:0002518
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to cell cycle checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_output","term_name":"premature cell cycle phase transition","termid":"FYPO:0000827"},{"relation_name":"is_a","term_name":"abnormal response to mitotic cell cycle checkpoint signaling","termid":"FYPO:0002517"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000298","FYPO:0005447","FYPO:0001985","FYPO:0000631","FYPO:0001320"],"is_obsolete":false,"name":"abolished response to mitotic cell cycle checkpoint signaling","synonyms":[{"name":"abolished cell cycle checkpoint arrest","type":"related"},{"name":"cell cycle arrest resulting from mitotic cell cycle checkpoint activation abolished","type":"exact"}],"termid":"FYPO:0002518"}


id: MONDO:0001301
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Rumination disorder is the backward flow of recently eaten food from the stomach to the mouth. The food is then re-chewed and swallowed or spat out. A non-purposeful contraction of stomach muscles is involved in rumination. It may be initially triggered by a viral illness, emotional distress, or physical injury. In many cases, no underlying trigger is identified. Behavioral therapy is the mainstay of treatment.","direct_ancestors":[{"relation_name":"is_a","term_name":"eating disorder","termid":"MONDO:0005451"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rumination disorder","secondary_identifiers":["MESH:D019959","DOID:11507","NCIT:C92567","SCTID:192014006","UMLS:C0154575","MEDGEN:102311","icd11.foundation:879747857","ICD9:307.53"],"synonyms":[{"name":"psychogenic rumination","type":"exact"},{"name":"rumination","type":"exact"},{"name":"rumination syndrome","type":"related"}],"termid":"MONDO:0001301","xrefs":{"Monarch":{"xref_id":"0001301"}}}


id: PBO:0062714
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 51 subfamily K member 1 pseudogene","termid":"PBO:0062714"}


id: PBO:0035900
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_re-entry_into_mitotic_cell_cycle_after_arrest_in_response_to_heat_shock","termid":"PBO:0035900"}


id: PBO:0000005
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene characterisation status","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fission yeast specific family","termid":"PBO:0000005"}


id: GO:0032997
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005886"],"is_obsolete":false,"name":"Fc receptor complex","synonyms":[{"name":"Fc-receptor complex","type":"exact"},{"name":"FcR complex","type":"exact"},{"name":"immunoglobulin receptor complex","type":"broad"}],"termid":"GO:0032997"}


id: PBO:0048916
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A8 family member K","termid":"PBO:0048916"}


id: PBO:0091425
data:
  {"annotation_feature_type":"gene","cv_name":"subunit_composition","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetrameric(1)","termid":"PBO:0091425"}


id: PBO:0074633
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 27","termid":"PBO:0074633"}


id: PBO:0028239
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_nucleus_during_meiotic_anaphase_II","termid":"PBO:0028239"}


id: GO:0097025
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.","definition_xrefs":["GOC:BHF","PMID:17237226"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"},{"relation_name":"part_of","term_name":"adherens junction","termid":"GO:0005912"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005886","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"MPP7-DLG1-LIN7 complex","termid":"GO:0097025"}


id: PBO:0074171
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 36 member 2","termid":"PBO:0074171"}


id: MONDO:0014648
data:
  {"annotated_genes":["SJAG_01625"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84347],"is_not":false,"summary":null,"term":"MONDO:0014648"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01625":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0005066","MONDO:0006025"],"is_obsolete":false,"name":"Al-Raqad syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:616459","MEDGEN:897610","UMLS:C4085595"],"synonyms":[{"name":"AL-RAQAD syndrome","type":"related"},{"name":"ARS","type":"related"},{"name":"Al-Raqad syndrome","type":"exact"}],"termid":"MONDO:0014648","terms_by_termid":{"MONDO:0014648":null},"xrefs":{"Monarch":{"xref_id":"0014648"}}}


id: PBO:0084552
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Member of the seripauperin multigene family; encoded mainly in subtelomeric regions; induced during alcoholic fermentation; induced by low temperature and also by anaerobic conditions; negatively regulated by oxygen and repressed by heme","termid":"PBO:0084552"}


id: MONDO:0004808
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"breast benign neoplasm","termid":"MONDO:0000620"},{"relation_name":"is_a","term_name":"integumentary system disorder","termid":"MONDO:0002051"},{"relation_name":"is_a","term_name":"breast disorder","termid":"MONDO:0002657"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign mammary dysplasia","secondary_identifiers":["ICD9:610.8","DOID:9504","ICD9:610.9","UMLS:C1305934","SCTID:57993004","MEDGEN:726820"],"synonyms":[{"name":"benign dysplasia of breast","type":"related"},{"name":"benign mammary dysplasia","type":"exact"}],"termid":"MONDO:0004808","xrefs":{"Monarch":{"xref_id":"0004808"}}}


id: MONDO:0009402
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A very rare syndrome associating an acro-fronto-facio-nasal dysostosis with genitourinary anomalies.","definition_xrefs":["Orphanet:2211"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"acrofrontofacionasal dysostosis","termid":"MONDO:0008715"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"acrofrontofacionasal dysostosis 2","secondary_identifiers":["OMIM:239710","MEDGEN:383797","GARD:287","MESH:C538332","SCTID:721835008","UMLS:C1855904"],"synonyms":[{"name":"AFFN dysostosis 2","type":"related"},{"name":"Naguib syndrome","type":"related"},{"name":"Naguib-Richieri-Costa syndrome","type":"exact"},{"name":"acrofrontofacionasal dysostosis 2","type":"exact"},{"name":"acrofrontofacionasal dysostosis type 2","type":"exact"},{"name":"acrofrontofacionasal dysostosis with genitourinary anomalies","type":"related"},{"name":"acrofrontofacionasal dysostosis, severe","type":"related"},{"name":"acrofrontofacionasal syndrome type 2","type":"exact"},{"name":"hypertelorism hypospadias polysyndactyly syndrome","type":"related"},{"name":"hypertelorism, hypospadias, and polysyndactyly syndrome","type":"related"},{"name":"hypertelorism-hypospadias-polysyndactyly syndrome","type":"exact"}],"termid":"MONDO:0009402","xrefs":{"Monarch":{"xref_id":"0009402"}}}


id: PBO:0054373
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1767","termid":"PBO:0054373"}


id: GO:0035013
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the peptide myosuppressin to initiate a change in cell activity.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled peptide receptor activity","termid":"GO:0008528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"myosuppressin receptor activity","termid":"GO:0035013"}


id: PBO:0070516
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L6 pseudogene 15","termid":"PBO:0070516"}


id: PBO:0064326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plastin 1","termid":"PBO:0064326"}


id: PBO:0051951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol-trisphosphate 3-kinase C","termid":"PBO:0051951"}


id: PBO:0018137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial iron ion transmembrane transporter Mmt1 (predicted)","termid":"PBO:0018137"}


id: PBO:0065909
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAB GTPase activating protein 1","termid":"PBO:0065909"}


id: PBO:0051853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iroquois homeobox 6","termid":"PBO:0051853"}


id: FYPO:0000677
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transport phenotype in which protein localization to the prospore membrane is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization","termid":"FYPO:0001370"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abnormal protein localization to prospore membrane","synonyms":[{"name":"abnormal protein localisation to prospore membrane","type":"exact"},{"name":"abnormal protein localization to forespore membrane","type":"exact"}],"termid":"FYPO:0000677"}


id: GO:0097727
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell.","definition_xrefs":["PMID:22691130","GOC:tb","PMID:25047614","GOC:cilia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular membraneless organelle","termid":"GO:0043232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"blepharoplast","termid":"GO:0097727"}


id: RO:0002323
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A mereological relationship or a topological relationship","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mereotopologically_related_to","termid":"RO:0002323"}


id: GO:0035550
data:
  {"annotated_genes":["SJAG_02766"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[90653],"is_not":false,"summary":null,"term":"GO:0035550"}]},"cv_name":"cellular_component","definition":"A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).","definition_xrefs":["InterPro:IPR008221","PMID:2651866"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02766":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"urease complex","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0035550","terms_by_termid":{"GO:0035550":null}}


id: GO:0061214
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney smooth muscle tissue development","termid":"GO:0072194"},{"relation_name":"part_of","term_name":"mesonephros development","termid":"GO:0001823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric smooth muscle tissue development","termid":"GO:0061214"}


id: PBO:0045271
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynamin 1 pseudogene 18","termid":"PBO:0045271"}


id: GO:0003986
data:
  {"annotated_genes":["SJAG_02985","SJAG_02769"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76059,90648],"is_not":false,"summary":null,"term":"GO:0003986"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: acetyl-CoA + H2O = acetate + CoA + H+.","definition_xrefs":["RHEA:20289","EC:3.1.2.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA hydrolase activity","termid":"GO:0016289"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02769":null,"SJAG_02985":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0016788","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"acetyl-CoA hydrolase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["KEGG_REACTION:R00227","Reactome:R-HSA-390304","MetaCyc:ACETYL-COA-HYDROLASE-RXN","Reactome:R-HSA-2066779"],"synonyms":[{"name":"acetyl coenzyme A acylase activity","type":"related"},{"name":"acetyl coenzyme A deacylase activity","type":"related"},{"name":"acetyl coenzyme A hydrolase activity","type":"related"},{"name":"acetyl-CoA acylase activity","type":"related"},{"name":"acetyl-CoA deacylase activity","type":"related"},{"name":"acetyl-CoA thiol esterase activity","type":"related"}],"termid":"GO:0003986","terms_by_termid":{"GO:0003986":null}}


id: MONDO:0007696
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital limb malformation","termid":"MONDO:0019054"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Emery-Nelson syndrome","secondary_identifiers":["Orphanet:1927","UMLS:C1841693","MEDGEN:333892","MESH:C535626","OMIM:139750","GARD:2593"],"synonyms":[{"name":"familial syndrome of short stature, deformities of the hands and feet, and unusual facies","type":"related"},{"name":"hand and foot deformity - flat facies","type":"related"},{"name":"hand and foot deformity with flat facies","type":"related"},{"name":"hand and foot deformity-flat facies syndrome","type":"exact"}],"termid":"MONDO:0007696","xrefs":{"Monarch":{"xref_id":"0007696"}}}


id: GO:0047395
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = sn-glycerol 3-phosphate + myo-inositol + H+.","definition_xrefs":["EC:3.1.4.44","RHEA:16501"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphoric diester hydrolase activity","termid":"GO:0008081"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824","GO:0016788"],"is_obsolete":false,"name":"glycerophosphoinositol glycerophosphodiesterase activity","secondary_identifiers":["MetaCyc:3.1.4.44-RXN","Reactome:R-HSA-6813740","KEGG_REACTION:R01193"],"synonyms":[{"name":"1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity","type":"related"},{"name":"sn-glycero(3)phosphoinositol glycerophosphohydrolase activity","type":"related"},{"name":"sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity","type":"related"}],"termid":"GO:0047395"}


id: GO:0035076
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A nuclear receptor-mediated signaling pathway initiated by an ecdysone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear receptor-mediated steroid hormone signaling pathway","termid":"GO:0030518"},{"relation_name":"part_of","term_name":"cellular response to ecdysone","termid":"GO:0071390"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"ecdysone receptor signaling pathway","synonyms":[{"name":"ecdysone receptor-mediated signalling pathway","type":"exact"},{"name":"nuclear receptor-mediated ecdysone signaling pathway","type":"exact"}],"termid":"GO:0035076"}


id: PBO:0029639
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_TPCK","termid":"PBO:0029639"}


id: GO:1904589
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein import.","definition_xrefs":["PMID:11406629","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein transport","termid":"GO:0051223"},{"relation_name":"regulates","term_name":"protein import","termid":"GO:0017038"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of protein import","synonyms":[{"name":"regulation of protein uptake","type":"exact"}],"termid":"GO:1904589"}


id: PBO:0043973
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"citrate synthase","termid":"PBO:0043973"}


id: PBO:0068970
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 214, pseudogene","termid":"PBO:0068970"}


id: GO:0038203
data:
  {"annotated_genes":["SJAG_04987","SJAG_06588","SJAG_03067","SJAG_04206","SJAG_01320","SJAG_00117","SJAG_01020","SJAG_00143","SJAG_05030","SJAG_04460"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[98573,100943,101910,105844,107729,117506],"is_not":false,"summary":null,"term":"GO:0038203"},{"annotations":[115410],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1903940"},{"annotations":[106153,90399,96939],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1904515"}]},"cv_name":"biological_process","definition":"A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.","definition_xrefs":["GOC:lb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TOR signaling","termid":"GO:0031929"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00117":null,"SJAG_00143":null,"SJAG_01020":null,"SJAG_01320":null,"SJAG_03067":null,"SJAG_04206":null,"SJAG_04460":null,"SJAG_04987":null,"SJAG_05030":null,"SJAG_06588":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"TORC2 signaling","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"TORC2 signal transduction","type":"exact"}],"termid":"GO:0038203","terms_by_termid":{"GO:0038203":null,"GO:1903940":null,"GO:1904515":null}}


id: GO:2000597
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of optic nerve formation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of optic nerve formation","termid":"GO:2000595"},{"relation_name":"positively_regulates","term_name":"optic nerve formation","termid":"GO:0021634"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of optic nerve formation","synonyms":[{"name":"positive regulation of CN II biosynthesis","type":"related"},{"name":"positive regulation of CN II formation","type":"related"}],"termid":"GO:2000597"}


id: PBO:0087925
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; relocalizes to the cytosol in response to hypoxia; PDR1 has a paralog, PDR3, that arose from the whole genome duplication","termid":"PBO:0087925"}


id: PBO:0042144
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine ligand 4","termid":"PBO:0042144"}


id: GO:0097690
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter.","definition_xrefs":["GOC:kom","PMID:15514116","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transporter inhibitor activity","termid":"GO:0141110"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0098772","GO:0140678"],"is_obsolete":false,"name":"iron ion transmembrane transporter inhibitor activity","synonyms":[{"name":"iron channel inhibitor activity","type":"exact"}],"termid":"GO:0097690"}


id: GO:0018803
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.","definition_xrefs":["EC:4.1.2.34"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity","secondary_identifiers":["MetaCyc:4.1.2.34-RXN","RHEA:16453","UM-BBD_reactionID:r0487"],"synonyms":[{"name":"(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity","type":"narrow"},{"name":"(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)","type":"related"},{"name":"(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity","type":"narrow"},{"name":"2'-carboxybenzalpyruvate aldolase activity","type":"related"},{"name":"trans-2'-carboxybenzalpyruvate hydratase-aldolase activity","type":"exact"}],"termid":"GO:0018803"}


id: PBO:0054365
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1758","termid":"PBO:0054365"}


id: PBO:0046863
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fumarylacetoacetate hydrolase domain containing 2A","termid":"PBO:0046863"}


id: PBO:0073861
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 9 member A9","termid":"PBO:0073861"}


id: PBO:0090735
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP kinase cascade scaffold protein Ahk1","termid":"PBO:0090735"}


id: GO:0046193
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phenol-containing compound catabolic process","termid":"GO:0019336"},{"relation_name":"is_a","term_name":"anaerobic phenol-containing compound metabolic process","termid":"GO:0042215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"anaerobic phenol-containing compound catabolic process","synonyms":[{"name":"anaerobic phenol-containing compound breakdown","type":"exact"},{"name":"anaerobic phenol-containing compound catabolism","type":"exact"},{"name":"anaerobic phenol-containing compound degradation","type":"exact"}],"termid":"GO:0046193"}


id: PBO:0059269
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein L33","termid":"PBO:0059269"}


id: GO:1901185
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.","definition_xrefs":["GOC:TermGenie","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"regulation of ERBB signaling pathway","termid":"GO:1901184"},{"relation_name":"negatively_regulates","term_name":"ERBB signaling pathway","termid":"GO:0038127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of ERBB signaling pathway","synonyms":[{"name":"down regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"down regulation of EGFR family signaling pathway","type":"related"},{"name":"down regulation of ERBB signaling pathway","type":"exact"},{"name":"down regulation of ERBB signalling pathway","type":"exact"},{"name":"down regulation of ErbB signaling","type":"exact"},{"name":"down-regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"down-regulation of EGFR family signaling pathway","type":"related"},{"name":"down-regulation of ERBB signaling pathway","type":"exact"},{"name":"down-regulation of ERBB signalling pathway","type":"exact"},{"name":"down-regulation of ErbB signaling","type":"exact"},{"name":"downregulation of EGF receptor family signaling pathway","type":"exact"},{"name":"downregulation of EGFR family signaling pathway","type":"related"},{"name":"downregulation of ERBB signaling pathway","type":"exact"},{"name":"downregulation of ERBB signalling pathway","type":"exact"},{"name":"downregulation of ErbB signaling","type":"exact"},{"name":"inhibition of EGF receptor family signaling pathway","type":"exact"},{"name":"inhibition of EGFR family signaling pathway","type":"related"},{"name":"inhibition of ERBB signaling pathway","type":"narrow"},{"name":"inhibition of ERBB signalling pathway","type":"exact"},{"name":"inhibition of ErbB signaling","type":"exact"},{"name":"negative regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"negative regulation of EGFR family signaling pathway","type":"related"},{"name":"negative regulation of ERBB signalling pathway","type":"exact"},{"name":"negative regulation of ErbB signaling","type":"exact"}],"termid":"GO:1901185"}


id: MONDO:0006026
data:
  {"annotated_genes":["SJAG_04277","SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86509],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012672"},{"annotations":[85514],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0001187"}]},"cv_name":"mondo","definition":"A disease involving the urinary bladder.","direct_ancestors":[{"relation_name":"is_a","term_name":"urinary system disorder","termid":"MONDO:0002118"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03453":null,"SJAG_04277":null},"genotype_count":0,"is_obsolete":false,"name":"urinary bladder disorder","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:596.9","EFO:1000018","MEDGEN:2278","DOID:365","ICD9:596.8","MESH:D001745","NCIT:C2900","SCTID:42643001","UMLS:C0005686"],"synonyms":[{"name":"bladder disease","type":"exact"},{"name":"bladder disorder","type":"exact"},{"name":"disease of urinary bladder","type":"exact"},{"name":"disease or disorder of urinary bladder","type":"exact"},{"name":"disorder of urinary bladder","type":"exact"},{"name":"urinary bladder disease","type":"exact"},{"name":"urinary bladder disease or disorder","type":"exact"},{"name":"urinary bladder disorder","type":"exact"}],"termid":"MONDO:0006026","terms_by_termid":{"MONDO:0001187":null,"MONDO:0012672":null},"xrefs":{"Monarch":{"xref_id":"0006026"}}}


id: PBO:0111648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"negative cofactor 2 complex subunit Ncb2","termid":"PBO:0111648"}


id: SO:0000110
data:
  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extent of continuous biological 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id: PBO:0108579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ASTRA complex subunit, armadillo-type fold Tti1","termid":"PBO:0108579"}


id: MONDO:0004590
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete fundus dystrophy (obsolete MONDO:0004590)","termid":"MONDO:0004590","xrefs":{"Monarch":{"xref_id":"0004590"}}}


id: GO:0098931
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.","definition_xrefs":["GOC:dos","VZ:3949"],"direct_ancestors":[{"relation_name":"is_a","term_name":"virion attachment to host cell","termid":"GO:0019062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"virion attachment to host cell flagellum","termid":"GO:0098931"}


id: FYPO:0007167
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type) during prophase of the first meiotic nuclear division.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization during meiosis","termid":"FYPO:0003790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000138","FYPO:0000257"],"is_obsolete":false,"name":"normal protein localization to cell cortex during meiotic prophase I","synonyms":[{"name":"normal protein localisation to cell cortex during meiotic prophase I","type":"exact"},{"name":"normal protein localisation to cell cortex during prophase I","type":"exact"}],"termid":"FYPO:0007167"}


id: MONDO:0020317
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute myeloid leukemia associated with t(9;11)(p22.3;q23.3) and MLLT3-KMT2A fusion protein expression. Morphologically it usually has monocytic features. It may present at any age but it is more commonly seen in children. Patients may present with disseminated intravascular coagulation.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute myeloid leukemia","termid":"MONDO:0018874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046","MONDO:0004992"],"is_obsolete":false,"name":"acute myeloid leukemia with 11q23 abnormalities","secondary_identifiers":["UMLS:C1292775","GARD:19587","ICDO:9897/3","Orphanet:98831","SCTID:444911000","MEDGEN:266234","NCIT:C82403"],"synonyms":[{"name":"AML with 11q23 abnormalities","type":"exact"},{"name":"AML with t(9;11)(p22;q23); MLLT3-MLL","type":"exact"},{"name":"acute myeloid Leukaemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A","type":"exact"},{"name":"acute myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A","type":"exact"},{"name":"acute myeloid leukaemia with 11q23 (MLL) abnormalities","type":"exact"},{"name":"acute myeloid leukaemia with MLL abnormalities","type":"exact"},{"name":"acute myeloid leukaemia with t(9;11)(p22.3;q23.3); MLLT3-KMT2A","type":"exact"},{"name":"acute myeloid leukaemia with t(9;11)(p22;q23); MLLT3-MLL","type":"exact"},{"name":"acute myeloid leukemia with 11q23 (MLL) abnormalities","type":"exact"},{"name":"acute myeloid leukemia with MLL abnormalities","type":"exact"},{"name":"acute myeloid leukemia with t(9;11)(p22.3;q23.3); MLLT3-KMT2A","type":"exact"},{"name":"acute myeloid leukemia with t(9;11)(p22;q23); MLLT3-MLL","type":"exact"}],"termid":"MONDO:0020317","xrefs":{"Monarch":{"xref_id":"0020317"}}}


id: PBO:0029378
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_UV_during_G0","termid":"PBO:0029378"}


id: PBO:0016069
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor zf-C2H2 type","termid":"PBO:0016069"}


id: PBO:0044247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cut like homeobox 2 pseudogene 2","termid":"PBO:0044247"}


id: PBO:0000460
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit S24 (predicted)","termid":"PBO:0000460"}


id: PBO:0005136
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial DNAJ domain protein Mdj1 (predicted)","termid":"PBO:0005136"}


id: MONDO:0014343
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Desbuquois dysplasia in which the cause of the disease is a mutation in the XYLT1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Desbuquois dysplasia","termid":"MONDO:0015426"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"linkeropathy","termid":"MONDO:1040022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"Desbuquois dysplasia 2","secondary_identifiers":["GARD:16466","UMLS:C4014294","OMIM:615777","MEDGEN:862731"],"synonyms":[{"name":"Baratela-Scott syndrome","type":"exact"},{"name":"DBQD2","type":"related"},{"name":"Desbuquois dysplasia 2","type":"exact"},{"name":"Desbuquois dysplasia caused by mutation in XYLT1","type":"exact"},{"name":"Desbuquois dysplasia type 2","type":"exact"},{"name":"XYLT1 Desbuquois dysplasia","type":"exact"}],"termid":"MONDO:0014343","xrefs":{"Monarch":{"xref_id":"0014343"}}}


id: PBO:0073593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SHOC2 leucine rich repeat scaffold protein","termid":"PBO:0073593"}


id: GO:1900678
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ferrichrome biosynthetic process","termid":"GO:1905568"},{"relation_name":"regulates","term_name":"ferricrocin biosynthetic process","termid":"GO:0031171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"regulation of ferricrocin biosynthetic process","synonyms":[{"name":"regulation of ferricrocin anabolism","type":"exact"},{"name":"regulation of ferricrocin biosynthesis","type":"exact"},{"name":"regulation of ferricrocin biosynthetic process, peptide formation","type":"narrow"},{"name":"regulation of ferricrocin biosynthetic process, peptide modification","type":"narrow"},{"name":"regulation of ferricrocin formation","type":"exact"},{"name":"regulation of ferricrocin synthesis","type":"exact"}],"termid":"GO:1900678"}


id: GO:0033865
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.","definition_xrefs":["GOC:pde","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside phosphate metabolic process","termid":"GO:0006753"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055086","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"nucleoside bisphosphate metabolic process","synonyms":[{"name":"nucleoside bisphosphate metabolism","type":"exact"}],"termid":"GO:0033865"}


id: GO:0030743
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methyladenosine(1067) in 23S rRNA + H+ + S-adenosyl-L-homocysteine.","definition_xrefs":["EC:2.1.1.230"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA (adenine) methyltransferase activity","termid":"GO:0016433"},{"relation_name":"is_a","term_name":"RNA 2'-O-methyltransferase activity","termid":"GO:0062105"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0016741","GO:0140098","GO:0003824"],"is_obsolete":false,"name":"23S rRNA (adenosine(1067)-2'-O)-methyltransferase activity","secondary_identifiers":["RHEA:43212","MetaCyc:RXN-12464"],"synonyms":[{"name":"RNA-pentose methylase activity","type":"related"},{"name":"S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity","type":"related"},{"name":"rRNA adenosine 2'-methylase activity","type":"related"},{"name":"ribosomal ribonucleate adenosine 2'-methyltransferase activity","type":"related"},{"name":"thiostrepton-resistance methylase activity","type":"narrow"}],"termid":"GO:0030743"}


id: PBO:0005097
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Meiotic mRNA Interception","termid":"PBO:0005097"}


id: PBO:0060651
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor corepressor 1","termid":"PBO:0060651"}


id: PBO:0085496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Proteasome-binding protein; interacts physically with multiple subunits of the 20S proteasome and genetically with genes encoding 20S core particle and 19S regulatory particle subunits; exhibits boundary activity which blocks the propagation of heterochromatic silencing; contains a PI31 proteasome regulator domain and sequence similarity with human PSMF1, a proteasome inhibitor; not an essential gene","termid":"PBO:0085496"}


id: FYPO:0001274
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is lower than normal. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein level during vegetative growth","termid":"FYPO:0001324"},{"relation_name":"is_a","term_name":"altered protein level during cellular response to hypoxia","termid":"FYPO:0001549"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0006551","FYPO:0000002","FYPO:0001985","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"decreased protein level during cellular response to hypoxia","synonyms":[{"name":"decreased protein accumulation during cellular response to hypoxia","type":"related"},{"name":"decreased protein level during cellular response to hypoxia during mitotic cell cycle","type":"related"},{"name":"decreased protein level during cellular response to hypoxia during vegetative growth","type":"exact"},{"name":"decreased protein level during cellular response to hypoxic stress","type":"exact"},{"name":"decreased protein level during cellular response to lowered oxygen tension","type":"exact"},{"name":"reduced protein level during cellular response to hypoxia","type":"exact"}],"termid":"FYPO:0001274"}


id: PBO:0084114
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; induced by treatment with 8-methoxypsoralen and UVA irradiation","termid":"PBO:0084114"}


id: FYPO:0004042
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms pieces of a septum rather than a septum that completely bisects the cell.","definition_xrefs":["PMID:21931816","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"incomplete septum","termid":"FYPO:0005870"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0000032","FYPO:0001985"],"is_obsolete":false,"name":"fragmented septum","synonyms":[{"name":"fragmented septum during mitotic cell cycle","type":"related"},{"name":"fragmented septum during vegetative growth","type":"exact"}],"termid":"FYPO:0004042"}


id: PBO:0034488
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_to_chromatin_at_boundary_element_IRC1L","termid":"PBO:0034488"}


id: MONDO:0002725
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete diffuse cutaneous mastocytosis (obsolete MONDO:0002725)","termid":"MONDO:0002725","xrefs":{"Monarch":{"xref_id":"0002725"}}}


id: GO:0032836
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.","definition_xrefs":["GOC:sr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extracellular matrix organization","termid":"GO:0030198"},{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"glomerulus development","termid":"GO:0032835"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glomerular basement membrane development","termid":"GO:0032836"}


id: MONDO:1010249
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ataxia telangiectasia that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune system disorder, non-human animal","termid":"MONDO:0700106"},{"relation_name":"is_a","term_name":"endocrine system disorder, non-human animal","termid":"MONDO:1011317"},{"relation_name":"is_a","term_name":"reproductive system disorder, non-human animal","termid":"MONDO:1011354"},{"relation_name":"is_a","term_name":"hereditary neurological disease, non-human animal","termid":"MONDO:1012972"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ataxia telangiectasia, non-human animal","secondary_identifiers":["OMIA:002044"],"termid":"MONDO:1010249","xrefs":{"Monarch":{"xref_id":"1010249"}}}


id: GO:0004577
data:
  {"annotated_genes":["SJAG_03311","SJAG_04821"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[97542,97880],"is_not":false,"summary":null,"term":"GO:0004577"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol.","definition_xrefs":["EC:2.4.1.141"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetylglucosaminyltransferase activity","termid":"GO:0008375"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03311":null,"SJAG_04821":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016757","GO:0016740"],"is_obsolete":false,"name":"N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-446207","RHEA:23380","MetaCyc:2.4.1.141-RXN","Reactome:R-HSA-5633241"],"synonyms":[{"name":"N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity","type":"related"},{"name":"UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity","type":"related"},{"name":"UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity","type":"related"},{"name":"uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity","type":"related"}],"termid":"GO:0004577","terms_by_termid":{"GO:0004577":null}}


id: PR:O94316
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 116 kDa U5 small nuclear ribonucleoprotein component that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03969","PRO:DNx","PANTHER:PTHR23115:SF5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pre-mRNA-splicing factor cwf10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC215.12","secondary_identifiers":["UniProtKB:O94316"],"synonyms":[{"name":"114 kDa U5 small nuclear ribonucleoprotein component homolog (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-EFTUD2","type":"exact"},{"name":"complexed with cdc5 protein 10 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94316"}


id: PBO:0039002
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"afadin, adherens junction formation factor","termid":"PBO:0039002"}


id: PBO:0061333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore complex interacting protein family member B11","termid":"PBO:0061333"}


id: PBO:0086363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative aldose 1-epimerase","termid":"PBO:0086363"}


id: GO:1902221
data:
  {"annotated_genes":["SJAG_05007","SJAG_00493","SJAG_01455","SJAG_03124","SJAG_04652","SJAG_03312","SJAG_00518"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[107761,89042],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009094"},{"annotations":[67759,60977],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006568"},{"annotations":[113939,89043,97547],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006571"},{"annotations":[105937],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006572"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.","definition_xrefs":["GOC:TermGenie","GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-amino acid metabolic process","termid":"GO:0170033"},{"relation_name":"is_a","term_name":"proteinogenic amino acid metabolic process","termid":"GO:0170039"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00493":null,"SJAG_00518":null,"SJAG_01455":null,"SJAG_03124":null,"SJAG_03312":null,"SJAG_04652":null,"SJAG_05007":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0006520","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000107":null},"synonyms":[{"name":"erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolism","type":"exact"}],"termid":"GO:1902221","terms_by_termid":{"GO:0006568":null,"GO:0006571":null,"GO:0006572":null,"GO:0009094":null}}


id: GO:0061298
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.","definition_xrefs":["GOC:dph","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vasculature development","termid":"GO:0001944"},{"relation_name":"part_of","term_name":"retina development in camera-type eye","termid":"GO:0060041"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"retina vasculature development in camera-type eye","synonyms":[{"name":"retinal vasculature development","type":"exact"}],"termid":"GO:0061298"}


id: MONDO:0015323
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete syndrome or malformation associated with head and neck malformations (obsolete MONDO:0015501)","termid":"MONDO:0015501"}],"gene_count":0,"genotype_count":0,"name":"obsolete teratogenic Pierre Robin syndrome (obsolete MONDO:0015323)","secondary_identifiers":["Orphanet:138059"],"synonyms":[{"name":"teratogenic Pierre Robin sequence","type":"exact"}],"termid":"MONDO:0015323","xrefs":{"Monarch":{"xref_id":"0015323"}}}


id: MOD:00753
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a chlorine atom for a hydrogen atom.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"halogen containing residue","termid":"MOD:00694"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chlorinated residue","synonyms":[{"name":"ClRes","type":"exact"}],"termid":"MOD:00753"}


id: PBO:0053431
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 376","termid":"PBO:0053431"}


id: GO:0090562
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).","definition_xrefs":["GOC:am","PMID:10913119"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-N(PI)-phosphohistidine-sugar phosphotransferase activity","termid":"GO:0008982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity","termid":"GO:0090562"}


id: PBO:0076452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TAGAP antisense RNA 1","termid":"PBO:0076452"}


id: MONDO:0002160
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete cerebral palsy (obsolete MONDO:0002160)","termid":"MONDO:0002160","xrefs":{"Monarch":{"xref_id":"0002160"}}}


id: PBO:0044386
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 2 subfamily A member 13","termid":"PBO:0044386"}


id: MONDO:0100567
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare hereditary angioedema characterized by potentially life-threatening episodes of subcutaneous and/or submucosal edema without urticaria and with normal levels and function of C1 esterase inhibitor. Patients present with prolonged attacks which last for approximately two to five days and may include nonpitting edema of the skin, severe abdominal symptoms such as pain and swelling, and/or respiratory distress due to upper respiratory airways involvement. Affected locations and frequency of attacks differ slightly between subtypes. Estrogen-containing oral contraceptives and pregnancy are precipitating factors, especially in patients with a factor XII mutation.","definition_xrefs":["Orphanet:528647"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary angioedema","termid":"MONDO:0019623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"hereditary angioedema with normal C1Inh","secondary_identifiers":["MEDGEN:743231","UMLS:C1960459","GARD:22195"],"synonyms":[{"name":"HAE with normal C1 inhibitor","type":"exact"},{"name":"HAE with normal C1Inh","type":"exact"},{"name":"hereditary angioedema with normal C1 inhibitor","type":"exact"},{"name":"hereditary angioneurotic edema with normal C1 inhibitor","type":"exact"},{"name":"hereditary angioneurotic edema with normal C1Inh","type":"exact"}],"termid":"MONDO:0100567","xrefs":{"Monarch":{"xref_id":"0100567"}}}


id: PBO:0004893
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial PPR repeat protein Ppr7","termid":"PBO:0004893"}


id: GO:0071935
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus.","definition_xrefs":["PMID:19609300","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"octopamine signaling pathway","termid":"GO:0071927"},{"relation_name":"part_of","term_name":"response to food","termid":"GO:0032094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"octopamine signaling pathway involved in response to food","synonyms":[{"name":"octopamine signalling pathway involved in response to food","type":"exact"}],"termid":"GO:0071935"}


id: GO:0010368
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized.","definition_xrefs":["GOC:tair_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoamylase complex","termid":"GO:0043033"},{"relation_name":"part_of","term_name":"chloroplast","termid":"GO:0009507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0032991"],"is_obsolete":false,"name":"chloroplast isoamylase complex","termid":"GO:0010368"}


id: GO:0034192
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactonate metabolic process","termid":"GO:0019583"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"D-galactonate metabolic process","synonyms":[{"name":"D-galactonate metabolism","type":"exact"}],"termid":"GO:0034192"}


id: MONDO:0000779
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A allergy involving a Malus domestica.","definition_xrefs":["MONDO:patterns/allergy"],"gene_count":0,"genotype_count":0,"name":"obsolete apple allergy (obsolete MONDO:0000779)","secondary_identifiers":["DOID:0060504"],"synonyms":[{"name":"Malus domestica allergic disease","type":"exact"},{"name":"Malus domestica caused allergic disease","type":"exact"},{"name":"Malus domestica fruit allergy","type":"exact"},{"name":"allergy of Malus domestica","type":"exact"}],"termid":"MONDO:0000779","xrefs":{"Monarch":{"xref_id":"0000779"}}}


id: MONDO:0005563
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, highly aggressive and lethal carcinoma that affects children and young adults. It arises from midline epithelial structures, most commonly the head, neck, and mediastinum. It is a poorly differentiated carcinoma and is characterized by mutations and rearrangement of the NUT gene. A balanced translocation t(15;19) is present that results in the creation of a fusion gene involving the NUT gene, most commonly BRD4-NUT fusion gene.","definition_xrefs":["NCIT:C45716"],"direct_ancestors":[{"relation_name":"is_a","term_name":"undifferentiated carcinoma","termid":"MONDO:0005617"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"nut midline carcinoma","secondary_identifiers":["GARD:21852","EFO:0005783","Orphanet:443167","Wikipedia:NUT_midline_carcinoma","MEDGEN:312999","DOID:0060463","ONCOTREE:NMCHN","UMLS:C1707291"],"synonyms":[{"name":"Midline carcinoma of children and Young adults with NUT rearrangement","type":"exact"},{"name":"NMC","type":"exact"},{"name":"NUT Midline carcinoma","type":"exact"},{"name":"NUT carcinoma","type":"exact"},{"name":"NUT midline carcinoma of the head and neck","type":"related"},{"name":"carcinoma with t(15;19)(q13;p13.1) translocation","type":"exact"},{"name":"nuclear protein in testis midline carcinoma","type":"exact"}],"termid":"MONDO:0005563","xrefs":{"Monarch":{"xref_id":"0005563"}}}


id: PBO:0110505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBXN2A pseudogene 1","termid":"PBO:0110505"}


id: MONDO:0020620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete blood group, ss (obsolete MONDO:0020620)","secondary_identifiers":["OMIM:111740"],"synonyms":[{"name":"BLOOD GROUP, Ss","type":"related"},{"name":"Ss","type":"related"},{"name":"Ss Blood Group","type":"related"},{"name":"blood group, Ss","type":"exact"}],"termid":"MONDO:0020620","xrefs":{"Monarch":{"xref_id":"0020620"}}}


id: PBO:0050539
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypoxanthine phosphoribosyltransferase 1","termid":"PBO:0050539"}


id: PBO:0087237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sequence-specific DNA binding protein; binds to a sequence motif associated with distinct genomic hotspots of non-H2B protein ubiquitylation (ub-hotspots); interacts with Slx5p to recruit the Slx5-Slx8  SUMO-targeted Ub ligase (STUbL) complex to ub-hotspots; deletion prevents ub-hotspot formation and exacerbates heat sensitivity of cells deficient in Rpd3L histone deacetylase complex members; forms nuclear foci upon DNA replication stress","termid":"PBO:0087237"}


id: PBO:0088961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein phosphatase PP2A regulatory subunit, PTPA family Ypa1","termid":"PBO:0088961"}


id: PBO:0089827
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial heat shock protein Hsp78","termid":"PBO:0089827"}


id: GO:0005178
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an integrin.","definition_xrefs":["GOC:ceb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signaling receptor binding","termid":"GO:0005102"},{"relation_name":"is_a","term_name":"protein-containing complex binding","termid":"GO:0044877"},{"relation_name":"is_a","term_name":"cell adhesion molecule binding","termid":"GO:0050839"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"integrin binding","synonyms":[{"name":"integrin ligand","type":"narrow"}],"termid":"GO:0005178"}


id: PBO:0075177
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNRPE pseudogene 7","termid":"PBO:0075177"}


id: PBO:0003355
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SR protein-specific kinase Dsk1","termid":"PBO:0003355"}


id: GO:0021729
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.","definition_xrefs":["GOC:jid","GOC:cls","GOC:dgh","GO_REF:0000021","GOC:dph","GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"medullary reticular formation development","termid":"GO:0021723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"superior reticular formation development","termid":"GO:0021729"}


id: PBO:0030898
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-regulation_phenotype_during_vegetative_growth","termid":"PBO:0030898"}


id: GO:0033012
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles.","definition_xrefs":["PMID:16563225","PMID:15090256"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"plasma membrane","termid":"GO:0005886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005886"],"is_obsolete":false,"name":"porosome","secondary_identifiers":["Wikipedia:Porosome"],"termid":"GO:0033012"}


id: _global:is_unit_of
data:
  {"annotation_feature_type":"gene","cv_name":"pato.ontology","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"is_unit_of","termid":"_global:is_unit_of"}


id: PBO:0090630
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myosin binding vezatin family protein involved in peroxisome inheritance Inp2","termid":"PBO:0090630"}


id: PBO:0061301
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neural proliferation, differentiation and control 1","termid":"PBO:0061301"}


id: PBO:0026752
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_phosphorylation_during_cellular_response_to_arginine","termid":"PBO:0026752"}


id: MONDO:0001686
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"borderline glaucoma","termid":"MONDO:0004744"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"anatomical narrow angle borderline glaucoma","secondary_identifiers":["MEDGEN:1843458","DOID:13327","UMLS:C0154941","ICD9:365.02"],"termid":"MONDO:0001686","xrefs":{"Monarch":{"xref_id":"0001686"}}}


id: PBO:0011057
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-requires_target_sequence_feature","termid":"PBO:0011057"}


id: PBO:0036278
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"palmitoyl-(protein) hydrolase (predicted)","termid":"PBO:0036278"}


id: PBO:0046716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EVA1C pseudogene 2","termid":"PBO:0046716"}


id: MOD:00738
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes an iron atom or a cluster containing iron for hydrogen atoms, or that coordinates an iron ion.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metal or metal cluster containing modified residue","termid":"MOD:00698"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iron containing modified residue","synonyms":[{"name":"FeRes","type":"exact"}],"termid":"MOD:00738"}


id: GO:0010709
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heteroduplex formation","termid":"GO:0030491"},{"relation_name":"part_of","term_name":"double-strand break repair via synthesis-dependent strand annealing","termid":"GO:0045003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006310"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006281"},{"rel_name":"part_of","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006310","GO:0006281","GO:0008150","GO:0006259"],"is_obsolete":false,"name":"heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing","termid":"GO:0010709"}


id: PBO:0076904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TEX101 pseudogene 1","termid":"PBO:0076904"}


id: MONDO:0019845
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acquired pituitary hormone deficiency","termid":"MONDO:0019832"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iatrogenic or traumatic pituitary deficiency","secondary_identifiers":["MEDGEN:575005","Orphanet:95619","GARD:19290","UMLS:C0342400"],"termid":"MONDO:0019845","xrefs":{"Monarch":{"xref_id":"0019845"}}}


id: MONDO:0000529
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete MONDO:0000529 (obsolete MONDO:0000529)","termid":"MONDO:0000529","xrefs":{"Monarch":{"xref_id":"0000529"}}}


id: PBO:0063724
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progesterone receptor membrane component 2","termid":"PBO:0063724"}


id: GO:0032397
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.","definition_xrefs":["PMID:9597134","PMID:11858820","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"MHC class I receptor activity","termid":"GO:0032393"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"activating MHC class I receptor activity","termid":"GO:0032397"}


id: PBO:0076068
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sperm-tail PG-rich repeat containing 4","termid":"PBO:0076068"}


id: MONDO:0013182
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"17p13.3 microduplication syndrome is characterized by variable psychomotor delay and dysmorphic features.","definition_xrefs":["Orphanet:217385"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"partial duplication of the short arm of chromosome 17","termid":"MONDO:0016950"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 17p13.3 duplication syndrome","secondary_identifiers":["DOID:0060432","OMIM:613215","GARD:17122","SCTID:719582007","MEDGEN:814630","MESH:C567705","UMLS:C3808300"],"synonyms":[{"name":"17p13.3 duplication syndrome","type":"exact"},{"name":"17p13.3 microduplication syndrome","type":"exact"},{"name":"chromosome 17p13.3 centromeric duplication syndrome","type":"exact"},{"name":"chromosome 17p13.3, centromeric, DUPLICATION syndrome","type":"related"},{"name":"dup(17)(p13.3)","type":"exact"},{"name":"trisomy 17p13.3","type":"exact"}],"termid":"MONDO:0013182","xrefs":{"Monarch":{"xref_id":"0013182"}}}


id: PBO:0069143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 394, pseudogene","termid":"PBO:0069143"}


id: GO:0042562
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"binding","termid":"GO:0005488"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"hormone binding","termid":"GO:0042562"}


id: MONDO:0024227
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A miliaria that is characterized by pustules resulting from inflammation and bacterial infection.","definition_xrefs":["DOID:0070319"],"direct_ancestors":[{"relation_name":"is_a","term_name":"miliaria","termid":"MONDO:0006580"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"miliaria pustulosa","secondary_identifiers":["UMLS:C0026114","MEDGEN:507949","SCTID:26988005"],"termid":"MONDO:0024227","xrefs":{"Monarch":{"xref_id":"0024227"}}}


id: PBO:0045769
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"extracellular matrix protein 1","termid":"PBO:0045769"}


id: MONDO:0027668
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"poisoning","termid":"MONDO:0029000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"flucloxacilline toxicity","secondary_identifiers":["Orphanet:240871"],"termid":"MONDO:0027668","xrefs":{"Monarch":{"xref_id":"0027668"}}}


id: GO:0002070
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell maturation","termid":"GO:0048469"},{"relation_name":"part_of","term_name":"epithelial cell development","termid":"GO:0002064"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"epithelial cell maturation","termid":"GO:0002070"}


id: PBO:0044837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 125","termid":"PBO:0044837"}


id: MOD:01979
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-threonine residue to O-(L-isoglutamyl)-L-threonine, using free L-glutamine and releasing ammonia, or using a peptidyl L-glutamine and releasing ammonia.","definition_xrefs":["PubMed:8706862","RESID:AA0536"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified residue that can arise from different natural residues","termid":"MOD:00859"},{"relation_name":"is_a","term_name":"crosslinked L-threonine residue","termid":"MOD:02056"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O-(L-isoglutamyl)-L-threonine","synonyms":[{"name":"(2S)-2-amino-5-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)-5-oxopentanoic acid","type":"exact"},{"name":"(2S,3R)-2-amino-3-([(4S)-4-amino-4-carboxybutanoyl]oxy)-propanoic acid","type":"exact"},{"name":"5-(threon-O3-yl)glutamate","type":"exact"},{"name":"O(beta)-(gamma-glutamyl)threonine","type":"exact"},{"name":"O-(L-isoglutamyl)-L-threonine","type":"exact"},{"name":"O3-(isoglutamyl)threonine","type":"exact"}],"termid":"MOD:01979"}


id: MONDO:0007927
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"macroglossia","termid":"MONDO:0015496"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital macroglossia","secondary_identifiers":["MESH:C531735","GARD:16599","OMIM:153630","SCTID:270516002","ICD9:750.15","MEDGEN:3588","Orphanet:2430","UMLS:C0009677","icd11.foundation:423141418"],"synonyms":[{"name":"macroglossia","type":"related"}],"termid":"MONDO:0007927","xrefs":{"Monarch":{"xref_id":"0007927"}}}


id: PBO:0050949
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interferon alpha and beta receptor subunit 1","termid":"PBO:0050949"}


id: MONDO:0019204
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Respiratory bronchiolitis - interstitial lung disease is a mild inflammatory pulmonary disorder developed by cigarette smokers and characterized by shortness of breath and cough, pulmonary function abnormalities of mixed restrictive and obstructive lung disease and high resolution CT scanning showing centrilobular micronodules, ground glass opacities and peribronchiolar thickening.","definition_xrefs":["Orphanet:79127"],"direct_ancestors":[{"relation_name":"is_a","term_name":"idiopathic interstitial pneumonia","termid":"MONDO:0002429"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"respiratory bronchiolitis-interstitial lung disease syndrome","secondary_identifiers":["GARD:18942","MEDGEN:1672485","icd11.foundation:822500243","UMLS:C1735355","MedDRA:10066393"],"synonyms":[{"name":"RB-ILD","type":"exact"}],"termid":"MONDO:0019204","xrefs":{"Monarch":{"xref_id":"0019204"}}}


id: FYPO:0007195
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are larger than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitochondrial morphology","termid":"FYPO:0000359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"large mitochondria","synonyms":[{"name":"enlarged mitochondria","type":"exact"},{"name":"large mitochondria during mitotic cell cycle","type":"related"},{"name":"large mitochondria during vegetative growth","type":"exact"}],"termid":"FYPO:0007195"}


id: PBO:0051052
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy diversity 2-15","termid":"PBO:0051052"}


id: PBO:0048129
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fucosyltransferase 9","termid":"PBO:0048129"}


id: PBO:0005642
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.6.5.5","termid":"PBO:0005642"}


id: GO:0071880
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.","definition_xrefs":["GOC:BHF","GOC:signaling","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenylate cyclase-activating G protein-coupled receptor signaling pathway","termid":"GO:0007189"},{"relation_name":"is_a","term_name":"adrenergic receptor signaling pathway","termid":"GO:0071875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"adenylate cyclase-activating adrenergic receptor signaling pathway","synonyms":[{"name":"activation of adenylate cyclase activity by adrenergic receptor signaling pathway","type":"related"},{"name":"activation of adenylate cyclase activity by adrenergic receptor signalling pathway","type":"exact"},{"name":"adrenergic receptor, adenylate cyclase activating pathway","type":"exact"},{"name":"adrenergic receptor, adenylyl cyclase activating pathway","type":"exact"}],"termid":"GO:0071880"}


id: FYPO:0007509
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah","PMID:17434129"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone H3-K9 trimethylation during vegetative growth","termid":"FYPO:0000879"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0002274","FYPO:0001985","FYPO:0001320","FYPO:0002494","FYPO:0005447"],"is_obsolete":false,"name":"increased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth","synonyms":[{"name":"increased histone H3 K9 trimethylation at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 trimethylation at mating-type region heterochromatin during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 trimethylation at silent mating-type cassette during mitotic cell cycle","type":"related"},{"name":"increased histone H3K9 trimethylation at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"increased histone H3K9me3 at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"increased histone lysine H3 K9 trimethylation at silent mating-type cassette during vegetative growth","type":"exact"}],"termid":"FYPO:0007509"}


id: PBO:0064328
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PLS1 pseudogene 1","termid":"PBO:0064328"}


id: PBO:0040057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin related protein 2/3 complex subunit 3 pseudogene 5","termid":"PBO:0040057"}


id: PBO:0042150
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine ligand 11","termid":"PBO:0042150"}


id: GO:0006942
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of striated muscle contraction.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of muscle contraction","termid":"GO:0006937"},{"relation_name":"regulates","term_name":"striated muscle contraction","termid":"GO:0006941"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of striated muscle contraction","termid":"GO:0006942"}


id: MONDO:0007118
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any anhidrosis in which the cause of the disease is a mutation in the ITPR2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anhidrosis","termid":"MONDO:0006527"},{"relation_name":"is_a","term_name":"subcutaneous tissue disorder","termid":"MONDO:0019296"},{"relation_name":"is_a","term_name":"dermis disorder","termid":"MONDO:0021154"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"isolated anhidrosis with normal sweat glands","secondary_identifiers":["Orphanet:468666","GARD:17843","DOID:0060603","OMIM:106190","MEDGEN:1800259","UMLS:C5568836"],"synonyms":[{"name":"ANHD","type":"related"},{"name":"Dann-Epstein-Sohar syndrome","type":"exact"},{"name":"ITPR2 anhidrosis","type":"exact"},{"name":"anhidrosis caused by mutation in ITPR2","type":"exact"},{"name":"anhidrosis, isolated, with normal sweat glands","type":"related"},{"name":"isolated generalised anhidrosis with normal sweat glands","type":"related"},{"name":"isolated generalized anhidrosis with normal sweat glands","type":"related"}],"termid":"MONDO:0007118","xrefs":{"Monarch":{"xref_id":"0007118"}}}


id: PR:O74857
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA-directed RNA polymerase III subunit RPC4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR13408:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III subunit rpc4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC18.07","secondary_identifiers":["UniProtKB:O74857"],"synonyms":[{"name":"RNA polymerase III subunit C4 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RNA polymerase III subunit C53 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPCC18.07","type":"related"},{"name":"Spom972h-POLR3D","type":"exact"},{"name":"rpc4","type":"related"}],"termid":"PR:O74857"}


id: MONDO:0030923
data:
  {"annotated_genes":["SJAG_03345","SJAG_04489"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85969],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013501"},{"annotations":[84550],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010936"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited neurodegenerative disorder","termid":"MONDO:0024237"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03345":null,"SJAG_04489":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"frontotemporal dementia and/or amyotrophic lateral sclerosis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIMPS:105500"],"termid":"MONDO:0030923","terms_by_termid":{"MONDO:0010936":null,"MONDO:0013501":null},"xrefs":{"Monarch":{"xref_id":"0030923"}}}


id: GO:0047116
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.","definition_xrefs":["EC:1.3.1.25","MetaCyc:1.3.1.25-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity","secondary_identifiers":["RHEA:11560"],"synonyms":[{"name":"(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)","type":"related"},{"name":"2-hydro-1,2-dihydroxybenzoate dehydrogenase activity","type":"related"},{"name":"3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity","type":"related"},{"name":"3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity","type":"related"},{"name":"DHB dehydrogenase activity","type":"related"},{"name":"DHBDH activity","type":"related"},{"name":"cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity","type":"related"},{"name":"cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity","type":"related"},{"name":"dihydrodihydroxybenzoate dehydrogenase activity","type":"related"}],"termid":"GO:0047116"}


id: PBO:0052636
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 8 pseudogene 4","termid":"PBO:0052636"}


id: FYPO:0006767
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is increased during the meiotic cell cycle, in cells that have not arrested the meiotic cell cycle under conditions that normally trigger meiotic DNA replication checkpoint signaling and response.","definition_xrefs":["PMID:10521402","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cyclin-dependent protein kinase activity","termid":"FYPO:0004319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0001985","FYPO:0000654","FYPO:0000707","FYPO:0000661"],"is_obsolete":false,"name":"increased cyclin-dependent protein kinase activity in absence of meiotic DNA replication checkpoint arrest","synonyms":[{"name":"increased cyclin-dependent protein kinase activity with abolished meiotic DNA replication checkpoint arrest","type":"exact"}],"termid":"FYPO:0006767"}


id: PBO:0080612
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 46","termid":"PBO:0080612"}


id: PBO:0068880
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 120, pseudogene","termid":"PBO:0068880"}


id: GO:0043592
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"endospore external encapsulating structure","termid":"GO:0043591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005618"}],"interesting_parent_ids":["GO:0005618","GO:0005575"],"is_obsolete":false,"name":"exosporium","synonyms":[{"name":"epispore","type":"related"},{"name":"exospore","type":"related"},{"name":"perispore","type":"related"}],"termid":"GO:0043592"}


id: GO:0120280
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium.","definition_xrefs":["ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"ciliary pro-basal body","synonyms":[{"name":"flagellar pro-basal body","type":"exact"},{"name":"flagellar probasal body","type":"exact"},{"name":"pro-basal body","type":"broad"},{"name":"pro-centriole","type":"broad"},{"name":"probasal body","type":"broad"}],"termid":"GO:0120280"}


id: PBO:0030979
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histone_H3-K9_dimethylation","termid":"PBO:0030979"}


id: PBO:0056338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP3K20 antisense RNA 1","termid":"PBO:0056338"}


id: PBO:0049200
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRIK1 antisense RNA 1","termid":"PBO:0049200"}


id: PBO:0002116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Tryptophan","termid":"PBO:0002116"}


id: PR:P78847
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A nuclear pore complex protein Nup205 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04901","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleoporin nup186 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC290.03c","secondary_identifiers":["UniProtKB:P78847"],"synonyms":[{"name":"Spom972h-NUP205","type":"exact"},{"name":"nuclear pore protein nup186 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P78847"}


id: GO:0019069
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The assembly of a virus capsid from its protein subunits.","definition_xrefs":["PMID:22615368","ISBN:0781702534"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral process","termid":"GO:0016032"},{"relation_name":"part_of","term_name":"virion assembly","termid":"GO:0019068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"viral capsid assembly","secondary_identifiers":["VZ:1950"],"termid":"GO:0019069"}


id: PBO:0086417
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative GTPase; associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation; recruited by ribosomal proteins L17, L35, and L37 to assembling ribosomes after 27SB pre-rRNA is generated, immediately preceding removal of ITS2","termid":"PBO:0086417"}


id: PBO:0067663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 841, pseudogene","termid":"PBO:0067663"}


id: MONDO:0011463
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic, autosomal recessive axonal hereditary motor and sensory neuropathy disease characterized by prenatal onset of a severe sensorimotor axonal polyneuropathy (reflected by reduced fetal movement and polyhydramnios), manifesting, at birth, with respiratory failure requiring mechanical ventilation, profound muscular hypotonia, rapidly progressing distal muscle weakness, and absent deep tendon reflexes, in the absence of contractures, leading to death before 8 months of age. Neuropathological findings show severe loss of large- and medium-sized myelinated fibers without signs of demyelination.","definition_xrefs":["Orphanet:538096"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polyneuropathy, lethal neonatal, axonal sensorimotor, autosomal recessive","secondary_identifiers":["MESH:C565773","UMLS:C1858353","OMIM:604431","GARD:17976","MEDGEN:348918"],"synonyms":[{"name":"polyneuropathy, lethal neonatal, axonal sensorimotor, autosomal recessive","type":"exact"}],"termid":"MONDO:0011463","xrefs":{"Monarch":{"xref_id":"0011463"}}}


id: MONDO:0011892
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any generalized epilepsy in which the cause of the disease is a mutation in the CACNB4 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epilepsy, idiopathic generalized, susceptibility to, 9","secondary_identifiers":["DOID:0111323","OMIM:607682","UMLS:C2750887","MEDGEN:413424"],"synonyms":[{"name":"CACNB4 generalised epilepsy","type":"exact"},{"name":"CACNB4 generalized epilepsy","type":"exact"},{"name":"EIG9","type":"related"},{"name":"epilepsy, idiopathic generalized, susceptibility to, 9","type":"exact"},{"name":"epilepsy, idiopathic generalized, susceptibility to, type 9","type":"exact"},{"name":"epilepsy, juvenile myoclonic, susceptibility to, 6","type":"related"},{"name":"generalised epilepsy caused by mutation in CACNB4","type":"exact"},{"name":"generalized epilepsy caused by mutation in CACNB4","type":"exact"},{"name":"susceptibility to idiopathic generalised epilepsy 9","type":"related"},{"name":"susceptibility to idiopathic generalized epilepsy 9","type":"related"}],"termid":"MONDO:0011892","xrefs":{"Monarch":{"xref_id":"0011892"}}}


id: GO:0060654
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the mammary gland sprout grows along its axis.","definition_xrefs":["GOC:dph","PMID:12558599"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branch elongation involved in mammary gland duct branching","termid":"GO:0060751"},{"relation_name":"part_of","term_name":"mammary gland cord morphogenesis","termid":"GO:0060652"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mammary gland cord elongation","termid":"GO:0060654"}


id: MONDO:0015264
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cryptogenic organizing pneumonia (COP) is a form of idiopathic interstitial pneumonia characterized pathologically by organizing pneumonia (OP) that presents with non-specific flu-like symptoms, as well as cough and dyspnea and where no etiological agent is found.","definition_xrefs":["Orphanet:1302"],"direct_ancestors":[{"relation_name":"is_a","term_name":"idiopathic interstitial pneumonia","termid":"MONDO:0002429"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cryptogenic organizing pneumonia","secondary_identifiers":["GARD:1620","icd11.foundation:1937662238","MEDGEN:116663","DOID:0050157","ICD9:516.36","MESH:D018549","NANDO:1200421","NCIT:C62586","SCTID:719218000","UMLS:C0242770","EFO:1001300","SCTID:68409003","NORD:873","ICD10CM:J84.116"],"synonyms":[{"name":"COP","type":"exact"},{"name":"Organizing Pneumonia","type":"exact"},{"name":"bronchiolitis obliterans organising pneumonia","type":"exact"},{"name":"bronchiolitis obliterans organizing pneumonia","type":"exact"},{"name":"constrictive bronchiolitis","type":"related"},{"name":"cryptogenic organising pneumonitis","type":"exact"},{"name":"cryptogenic organizing pneumonitis","type":"exact"},{"name":"idiopathic BOOP","type":"related"},{"name":"idiopathic bronchiolitis obliterans organising pneumonia","type":"related"},{"name":"idiopathic bronchiolitis obliterans organizing pneumonia","type":"related"},{"name":"idiopathic bronchiolitis obliterans with organising pneumonia","type":"exact"},{"name":"idiopathic bronchiolitis obliterans with organizing pneumonia","type":"exact"},{"name":"organising pneumonia","type":"exact"},{"name":"organizing pneumonia","type":"exact"}],"termid":"MONDO:0015264","xrefs":{"Monarch":{"xref_id":"0015264"}}}


id: PBO:0031552
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_peptidase_activity","termid":"PBO:0031552"}


id: PBO:0047120
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 166 member C","termid":"PBO:0047120"}


id: PBO:0001373
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"6.1.1.7","termid":"PBO:0001373"}


id: MONDO:0032892
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"structural brain anomalies with impaired intellectual development and craniosynostosis","secondary_identifiers":["UMLS:C5231485","MEDGEN:1684861","OMIM:618736"],"synonyms":[{"name":"BAIDCS","type":"related"},{"name":"STRUCTURAL BRAIN ANOMALIES WITH IMPAIRED INTELLECTUAL DEVELOPMENT AND CRANIOSYNOSTOSIS","type":"related"}],"termid":"MONDO:0032892","xrefs":{"Monarch":{"xref_id":"0032892"}}}


id: MONDO:0005567
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A substance-specific organic brain syndrome that follows the discontinuation of administration or use, or reduction in intake of a substance (including alcohol, prescribed medications and recreational drugs). Syndrome manifests with diverse, often painful physical and psychological symptoms, which include but not limited to intense drug craving, anxiety, depression, insomnia, nausea, perspiration, body aches, tremors, hallucinations, and convulsions.","definition_xrefs":["NCIT:C35046"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"mental disorder","termid":"MONDO:0005084"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"substance-related disorder","termid":"MONDO:0002494"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"substance withdrawal syndrome","secondary_identifiers":["DOID:0060001","EFO:0005800","MEDGEN:20990","MESH:D013375","SCTID:363101005","ICD9:292.0","UMLS:C0038587"],"synonyms":[{"name":"drug withdrawal","type":"exact"},{"name":"drug withdrawal syndrome","type":"exact"},{"name":"substance withdrawal","type":"exact"},{"name":"substance withdrawal disorder","type":"exact"},{"name":"substance withdrawal syndrome","type":"exact"},{"name":"withdrawal disorder","type":"related"},{"name":"withdrawal syndrome","type":"exact"}],"termid":"MONDO:0005567","xrefs":{"Monarch":{"xref_id":"0005567"}}}


id: GO:2000346
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of epithelial cell proliferation","termid":"GO:0050680"},{"relation_name":"is_a","term_name":"regulation of hepatocyte proliferation","termid":"GO:2000345"},{"relation_name":"negatively_regulates","term_name":"hepatocyte proliferation","termid":"GO:0072574"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of hepatocyte proliferation","termid":"GO:2000346"}


id: GO:0098621
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.","definition_xrefs":["RHEA:25041","PMID:17142313","PMID:19608919"],"direct_ancestors":[{"relation_name":"is_a","term_name":"selenotransferase activity","termid":"GO:0016785"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a tRNA","termid":"GO:0140101"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140101"}],"interesting_parent_ids":["GO:0140098","GO:0140101","GO:0003824","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"O-phosphoseryl-tRNA(Sec) selenium transferase activity","secondary_identifiers":["EC:2.9.1.2","Reactome:R-HSA-2408555"],"synonyms":[{"name":"O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase","type":"exact"},{"name":"O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase","type":"exact"},{"name":"SepSecS","type":"exact"},{"name":"phosphoseryl-selenocysteinyl-tRNA selenium transferase activity","type":"exact"}],"termid":"GO:0098621"}


id: GO:0042302
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"The action of a molecule that contributes to the structural integrity of a cuticle.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"structural molecule activity","termid":"GO:0005198"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005198"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005198"],"is_obsolete":false,"name":"structural constituent of cuticle","termid":"GO:0042302"}


id: PBO:0069644
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 921, pseudogene","termid":"PBO:0069644"}


id: MONDO:0005986
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with viruses of the genus torovirus, family coronaviridae.","definition_xrefs":["MESH:D018176"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Nidovirales infectious disease","termid":"MONDO:0005876"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"torovirus infectious disease","secondary_identifiers":["UMLS:C0206607","MEDGEN:104897"],"synonyms":[{"name":"Torovirus caused disease or disorder","type":"exact"},{"name":"Torovirus disease or disorder","type":"exact"},{"name":"Torovirus infectious disease","type":"exact"}],"termid":"MONDO:0005986","xrefs":{"Monarch":{"xref_id":"0005986"}}}


