# terms

id: PBO:0046609
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group K9, member 11","termid":"PBO:0046609"}


id: GO:0036513
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.","definition_xrefs":["PMID:15215856","GOC:PARL","GOC:bf","PMID:16186510"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"is_a","term_name":"endoplasmic reticulum protein-containing complex","termid":"GO:0140534"},{"relation_name":"part_of","term_name":"endoplasmic reticulum membrane","termid":"GO:0005789"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005783"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005789"}],"interesting_parent_ids":["GO:0005783","GO:0032991","GO:0005789","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"Derlin-1 retrotranslocation complex","synonyms":[{"name":"Derlin-1 complex","type":"exact"},{"name":"Derlin-1 protein dislocation complex","type":"exact"},{"name":"Derlin-1 retro-translocation complex","type":"exact"},{"name":"Derlin-1 retrotranslocon","type":"exact"},{"name":"ERAD protein dislocation complex","type":"exact"}],"termid":"GO:0036513"}


id: PR:O14170
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pop2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O14170"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat-containing protein pop2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4D7.03","synonyms":[{"name":"Spom972h-pop2","type":"exact"},{"name":"proteolysis factor sud1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14170"}


id: GO:0106038
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process carried out at the cellular level, which results in the arrangement of constituent parts of a vesicle. Vesicle assembly begins with membrane bending (GO:0097753) and ends with fusion of the vesicle after vesicle scission (GO:0099050).","definition_xrefs":["PMID:25898166","GOC:aruk","GOC:bc"],"gene_count":0,"genotype_count":0,"name":"obsolete vesicle assembly (obsolete GO:0106038)","synonyms":[{"name":"vesicle biosynthesis","type":"exact"},{"name":"vesicle formation","type":"exact"}],"termid":"GO:0106038"}


id: MONDO:1010101
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Galactosemia that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of orbital region, non-human animal","termid":"MONDO:1011315"},{"relation_name":"is_a","term_name":"disorder of visual system, non-human animal","termid":"MONDO:1011316"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"metabolic disease, non-human animal","termid":"MONDO:1011331"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"galactosemia, non-human animal","secondary_identifiers":["OMIA:001144"],"termid":"MONDO:1010101","xrefs":{"Monarch":{"xref_id":"1010101"}}}


id: PBO:0078106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trafficking protein particle complex subunit 13","termid":"PBO:0078106"}


id: MONDO:0005288
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Discrete abnormal tissue masses that protrude into the lumen of the intestine. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.","definition_xrefs":["MESH:D007417"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal disorder","termid":"MONDO:0005020"},{"relation_name":"is_a","term_name":"polyp","termid":"MONDO:0005079"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"intestinal polyp","secondary_identifiers":["ICD9:569.89","EFO:0003855","SCTID:254588001","UMLS:C0021846","MEDGEN:9526","HP:0005266"],"synonyms":[{"name":"intestinal polyp","type":"exact"},{"name":"intestinal polyp (disease)","type":"exact"}],"termid":"MONDO:0005288","xrefs":{"Monarch":{"xref_id":"0005288"}}}


id: PBO:0113140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor-like protein; involved in negatively regulating TORC1 activity; green fluorescent protein (GFP)-fusion protein localizes to the vacuole","termid":"PBO:0113140"}


id: GO:0031994
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to insulin-like growth factor I.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"insulin-like growth factor binding","termid":"GO:0005520"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"insulin-like growth factor I binding","synonyms":[{"name":"IGF-I binding","type":"exact"}],"termid":"GO:0031994"}


id: FYPO:0001310
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal phenotype","termid":"FYPO:0000257"},{"relation_name":"is_a","term_name":"cell population viability","termid":"FYPO:0002057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0000003","FYPO:0000257"],"is_obsolete":false,"name":"normal viability in stationary phase","synonyms":[{"name":"normal cell population viability in stationary phase","type":"exact"},{"name":"normal chronological cell aging","type":"related"},{"name":"normal chronological lifespan","type":"related"}],"termid":"FYPO:0001310"}


id: GO:0005803
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.","definition_xrefs":["ISBN:0198547684"],"gene_count":0,"genotype_count":0,"name":"obsolete secretory vesicle (obsolete GO:0005803)","synonyms":[{"name":"secretory vesicle","type":"exact"},{"name":"transition vesicle","type":"narrow"}],"termid":"GO:0005803"}


id: PATO:0001972
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A branched quality inhering in a bearer by virtue of the bearer's having secondary branches branching into a reticulum toward the margin.","definition_xrefs":["Hickey:1988"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branched","termid":"PATO:0000402"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"reticulodromous","termid":"PATO:0001972"}


id: PR:O42917
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- eso1 gene.","definition_xrefs":["UniProtKB:O42917","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-acetyltransferase eso1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16A3.11","synonyms":[{"name":"ECO1 homolog (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-eso1","type":"exact"},{"name":"sister chromatid cohesion protein eso1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42917"}


id: GO:0097398
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.","definition_xrefs":["GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to cytokine stimulus","termid":"GO:0071345"},{"relation_name":"is_a","term_name":"response to interleukin-17","termid":"GO:0097396"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to interleukin-17","synonyms":[{"name":"cellular response to IL-17","type":"exact"}],"termid":"GO:0097398"}


id: PR:O94296
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC887.12 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94296"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospholipid-transporting ATPase C887.12 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC887.12","synonyms":[{"name":"Spom972h-SPBC887.12","type":"exact"}],"termid":"PR:O94296"}


id: GO:1900687
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of small molecule metabolic process","termid":"GO:0062014"},{"relation_name":"is_a","term_name":"negative regulation of secondary metabolite biosynthetic process","termid":"GO:1900377"},{"relation_name":"is_a","term_name":"regulation of gerfelin biosynthetic process","termid":"GO:1900686"},{"relation_name":"negatively_regulates","term_name":"gerfelin biosynthetic process","termid":"GO:1900578"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"negatively_regulates","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0019748","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"negative regulation of gerfelin biosynthetic process","synonyms":[{"name":"down regulation of gerfelin anabolism","type":"exact"},{"name":"down regulation of gerfelin biosynthesis","type":"exact"},{"name":"down regulation of gerfelin biosynthetic process","type":"exact"},{"name":"down regulation of gerfelin formation","type":"exact"},{"name":"down regulation of gerfelin synthesis","type":"exact"},{"name":"down-regulation of gerfelin anabolism","type":"exact"},{"name":"down-regulation of gerfelin biosynthesis","type":"exact"},{"name":"down-regulation of gerfelin biosynthetic process","type":"exact"},{"name":"down-regulation of gerfelin formation","type":"exact"},{"name":"down-regulation of gerfelin synthesis","type":"exact"},{"name":"downregulation of gerfelin anabolism","type":"exact"},{"name":"downregulation of gerfelin biosynthesis","type":"exact"},{"name":"downregulation of gerfelin biosynthetic process","type":"exact"},{"name":"downregulation of gerfelin formation","type":"exact"},{"name":"downregulation of gerfelin synthesis","type":"exact"},{"name":"inhibition of gerfelin anabolism","type":"exact"},{"name":"inhibition of gerfelin biosynthesis","type":"exact"},{"name":"inhibition of gerfelin biosynthetic process","type":"narrow"},{"name":"inhibition of gerfelin formation","type":"exact"},{"name":"inhibition of gerfelin synthesis","type":"exact"},{"name":"negative regulation of gerfelin anabolism","type":"exact"},{"name":"negative regulation of gerfelin biosynthesis","type":"exact"},{"name":"negative regulation of gerfelin formation","type":"exact"},{"name":"negative regulation of gerfelin synthesis","type":"exact"}],"termid":"GO:1900687"}


id: PBO:0109051
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MSL3 pseudogene 2","termid":"PBO:0109051"}


id: GO:0060655
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.","definition_xrefs":["GOC:dph","PMID:12558599"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branching involved in mammary gland duct morphogenesis","termid":"GO:0060444"},{"relation_name":"part_of","term_name":"mammary gland cord morphogenesis","termid":"GO:0060652"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"branching involved in mammary gland cord morphogenesis","termid":"GO:0060655"}


id: MONDO:0020115
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Secondary polycythemia is an elevated absolute red blood cell mass caused by enhanced stimulation of red blood cell production by an otherwise normal erythroid lineage that may be congenital or acquired (congenital secondary polycythemia and acquired secondary polycythemia).","definition_xrefs":["Orphanet:98428"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete rare genetic hematologic disease (obsolete MONDO:0015549)","termid":"MONDO:0015549"},{"relation_name":"is_a","term_name":"polycythemia","termid":"MONDO:0005571"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"secondary polycythemia","secondary_identifiers":["MedDRA:10036062","GARD:19467","NCIT:C27178","UMLS:C1318533","MEDGEN:231144"],"synonyms":[{"name":"secondary erythrocytosis","type":"exact"},{"name":"secondary polycythemia","type":"exact"}],"termid":"MONDO:0020115","xrefs":{"Monarch":{"xref_id":"0020115"}}}


id: MOD:00476
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom with an galactose group through a glycosidic bond.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexosylated residue","termid":"MOD:00434"},{"relation_name":"is_a","term_name":"galactosylated","termid":"MOD:00728"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"galactosylated residue","synonyms":[{"name":"GalRes","type":"exact"}],"termid":"MOD:00476"}


id: PBO:0058800
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 7706","termid":"PBO:0058800"}


id: GO:0007135
data:
  {"annotated_genes":["SJAG_00678","SJAG_00486","SJAG_04271","SJAG_00207","SJAG_04508","SJAG_00646","SJAG_03989","SJAG_03090"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104593,106299,107186],"is_not":false,"summary":null,"term":"GO:0007135"},{"annotations":[93331,87383],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051456"},{"annotations":[112671,111135,87519],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0045144"}]},"cv_name":"biological_process","definition":"The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.","definition_xrefs":["GOC:dph","GOC:mah","ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiosis II cell cycle process","termid":"GO:0061983"},{"relation_name":"is_a","term_name":"meiotic nuclear division","termid":"GO:0140013"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00207":null,"SJAG_00486":null,"SJAG_00646":null,"SJAG_00678":null,"SJAG_03090":null,"SJAG_03989":null,"SJAG_04271":null,"SJAG_04508":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140013"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0140013"],"is_obsolete":false,"name":"meiosis II","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Wikipedia:Meiosis#Meiosis_II"],"synonyms":[{"name":"meiosis II nuclear division","type":"exact"}],"termid":"GO:0007135","terms_by_termid":{"GO:0007135":null,"GO:0045144":null,"GO:0051456":null}}


id: FYPO:0000741
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular pigment accumulation phenotype","termid":"FYPO:0000739"},{"relation_name":"is_a","term_name":"abnormal cellular process during vegetative growth","termid":"FYPO:0001362"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular pigment accumulation","synonyms":[{"name":"abnormal cellular pigment accumulation","type":"exact"},{"name":"altered colony color","type":"related"},{"name":"altered colony colour","type":"related"},{"name":"increased cellular pigment accumulation during mitotic cell cycle","type":"related"},{"name":"increased cellular pigment accumulation during vegetative growth","type":"exact"}],"termid":"FYPO:0000741"}


id: GO:1901032
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.","definition_xrefs":["GOC:kmv","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to reactive oxygen species","termid":"GO:1901031"},{"relation_name":"is_a","term_name":"negative regulation of response to oxidative stress","termid":"GO:1902883"},{"relation_name":"negatively_regulates","term_name":"response to reactive oxygen species","termid":"GO:0000302"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of response to reactive oxygen species","synonyms":[{"name":"down regulation of response to AOS","type":"exact"},{"name":"down regulation of response to ROI","type":"exact"},{"name":"down regulation of response to ROS","type":"exact"},{"name":"down regulation of response to active oxygen species","type":"exact"},{"name":"down regulation of response to reactive oxidative species","type":"exact"},{"name":"down regulation of response to reactive oxygen intermediate","type":"exact"},{"name":"down regulation of response to reactive oxygen species","type":"exact"},{"name":"down-regulation of response to AOS","type":"exact"},{"name":"down-regulation of response to ROI","type":"exact"},{"name":"down-regulation of response to ROS","type":"exact"},{"name":"down-regulation of response to active oxygen species","type":"exact"},{"name":"down-regulation of response to reactive oxidative species","type":"exact"},{"name":"down-regulation of response to reactive oxygen intermediate","type":"exact"},{"name":"down-regulation of response to reactive oxygen species","type":"exact"},{"name":"downregulation of response to AOS","type":"exact"},{"name":"downregulation of response to ROI","type":"exact"},{"name":"downregulation of response to ROS","type":"exact"},{"name":"downregulation of response to active oxygen species","type":"exact"},{"name":"downregulation of response to reactive oxidative species","type":"exact"},{"name":"downregulation of response to reactive oxygen intermediate","type":"exact"},{"name":"downregulation of response to reactive oxygen species","type":"exact"},{"name":"inhibition of response to AOS","type":"exact"},{"name":"inhibition of response to ROI","type":"exact"},{"name":"inhibition of response to ROS","type":"exact"},{"name":"inhibition of response to active oxygen species","type":"exact"},{"name":"inhibition of response to reactive oxidative species","type":"exact"},{"name":"inhibition of response to reactive oxygen intermediate","type":"exact"},{"name":"inhibition of response to reactive oxygen species","type":"narrow"},{"name":"negative regulation of response to AOS","type":"exact"},{"name":"negative regulation of response to ROI","type":"exact"},{"name":"negative regulation of response to ROS","type":"exact"},{"name":"negative regulation of response to active oxygen species","type":"exact"},{"name":"negative regulation of response to reactive oxidative species","type":"exact"},{"name":"negative regulation of response to reactive oxygen intermediate","type":"exact"}],"termid":"GO:1901032"}


id: GO:0075022
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete ethylene-mediated activation of appressorium formation (obsolete GO:0075022)","termid":"GO:0075022"}


id: PBO:0083614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on the cytoplasmic face of mitochondrial tubules at sites where division will occur; participates in endocytosis and regulates peroxisome fission along with Vps1p; mutants in the human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy","termid":"PBO:0083614"}


id: GO:0045625
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of T-helper 1 type immune response","termid":"GO:0002825"},{"relation_name":"is_a","term_name":"regulation of T-helper cell differentiation","termid":"GO:0045622"},{"relation_name":"regulates","term_name":"T-helper 1 cell differentiation","termid":"GO:0045063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of T-helper 1 cell differentiation","synonyms":[{"name":"regulation of T-helper 1 cell development","type":"related"}],"termid":"GO:0045625"}


id: GO:0003369
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.","definition_xrefs":["GOC:tb","GOC:ascb_2009","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of cell polarity involved in gastrulation cell migration","termid":"GO:0003379"},{"relation_name":"part_of","term_name":"cell migration involved in mesendoderm migration","termid":"GO:0090134"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007163"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007163","GO:0008150"],"is_obsolete":false,"name":"establishment of cell polarity involved in mesendodermal cell migration","termid":"GO:0003369"}


id: PBO:0073624
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sialic acid binding Ig like lectin 10","termid":"PBO:0073624"}


id: PBO:0039936
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho guanine nucleotide exchange factor 40","termid":"PBO:0039936"}


id: PBO:0047219
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 225 member A","termid":"PBO:0047219"}


id: PBO:0071139
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L22 pseudogene 2","termid":"PBO:0071139"}


id: PR:Q9USU3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fbh1 gene.","definition_xrefs":["UniProtKB:Q9USU3","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box DNA helicase protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC336.01","synonyms":[{"name":"Spom972h-fbh1","type":"exact"}],"termid":"PR:Q9USU3"}


id: GO:0032325
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molybdopterin cofactor metabolic process","termid":"GO:0043545"},{"relation_name":"is_a","term_name":"organophosphate catabolic process","termid":"GO:0046434"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"molybdopterin cofactor catabolic process","termid":"GO:0032325"}


id: GO:0015944
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways by which formate is converted to CO2.","definition_xrefs":["MetaCyc:PWY-1881"],"direct_ancestors":[{"relation_name":"is_a","term_name":"formate metabolic process","termid":"GO:0015942"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"formate oxidation","synonyms":[{"name":"formic acid oxidation","type":"exact"}],"termid":"GO:0015944"}


id: PBO:0055643
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3082","termid":"PBO:0055643"}


id: PBO:0056969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 25","termid":"PBO:0056969"}


id: PBO:0092005
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Lysine (uuu), mitochondrial","termid":"PBO:0092005"}


id: MONDO:0013151
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"central areolar choroidal dystrophy","termid":"MONDO:0008982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"choroidal dystrophy, central areolar, 3","secondary_identifiers":["MEDGEN:442631","MESH:C567729","GARD:15623","UMLS:C2751055","OMIM:613144"],"synonyms":[{"name":"CACD3","type":"exact"},{"name":"choroidal dystrophy, central areolar, 3","type":"exact"},{"name":"choroidal dystrophy, central areolar, with or without drusen","type":"related"}],"termid":"MONDO:0013151","xrefs":{"Monarch":{"xref_id":"0013151"}}}


id: GO:0045621
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lymphocyte differentiation","termid":"GO:0045619"},{"relation_name":"is_a","term_name":"positive regulation of lymphocyte activation","termid":"GO:0051251"},{"relation_name":"is_a","term_name":"positive regulation of leukocyte differentiation","termid":"GO:1902107"},{"relation_name":"positively_regulates","term_name":"lymphocyte differentiation","termid":"GO:0030098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of lymphocyte differentiation","synonyms":[{"name":"activation of lymphocyte differentiation","type":"narrow"},{"name":"positive regulation of lymphocyte development","type":"related"},{"name":"stimulation of lymphocyte differentiation","type":"narrow"},{"name":"up regulation of lymphocyte differentiation","type":"exact"},{"name":"up-regulation of lymphocyte differentiation","type":"exact"},{"name":"upregulation of lymphocyte differentiation","type":"exact"}],"termid":"GO:0045621"}


id: GO:0034390
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.","definition_xrefs":["CL:0000192","GOC:BHF","GOC:mah","GOC:mtg_apoptosis","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscle cell apoptotic process","termid":"GO:0010657"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"smooth muscle cell apoptotic process","synonyms":[{"name":"SMC apoptosis","type":"exact"},{"name":"apoptosis of smooth muscle cells","type":"exact"},{"name":"programmed cell death of smooth muscle cells by apoptosis","type":"exact"},{"name":"programmed cell death, smooth muscle cells","type":"exact"},{"name":"smooth muscle cell apoptosis","type":"narrow"},{"name":"smooth muscle cell programmed cell death by apoptosis","type":"exact"}],"termid":"GO:0034390"}


id: GO:0010989
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.","definition_xrefs":["GOC:BHF","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of lipoprotein particle clearance","termid":"GO:0010985"},{"relation_name":"is_a","term_name":"regulation of low-density lipoprotein particle clearance","termid":"GO:0010988"},{"relation_name":"negatively_regulates","term_name":"low-density lipoprotein particle clearance","termid":"GO:0034383"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of low-density lipoprotein particle clearance","termid":"GO:0010989"}


id: PBO:0072880
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SBDS pseudogene 1","termid":"PBO:0072880"}


id: PBO:0091429
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Carbohydrate Binding Module","termid":"PBO:0091429"}


id: FYPO:0006638
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is decreased, and the protein is instead detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortex.","definition_xrefs":["PomBase:mah","PMID:29930085"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to medial cortex during vegetative growth","termid":"FYPO:0002557"},{"relation_name":"is_a","term_name":"abnormal protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth","termid":"FYPO:0007405"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth","synonyms":[{"name":"abolished protein localization to medial cortex, with protein distributed in cortex, during vegetative growth","type":"narrow"},{"name":"decreased protein localisation to medial cortex, with protein distributed in cell cortex, during vegetative growth","type":"exact"},{"name":"decreased protein localization to medial cortex during vegetative growth, with protein distributed in cell cortex","type":"exact"},{"name":"decreased protein localization to medial cortex, with protein distributed in cell cortex, during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to medial ring, with protein distributed in cell cortex, during vegetative growth","type":"exact"},{"name":"reduced protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth","type":"exact"}],"termid":"FYPO:0006638"}


id: GO:1904197
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation.","definition_xrefs":["GO_REF:0000058","PMID:22383759","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of epithelial cell proliferation","termid":"GO:0050679"},{"relation_name":"is_a","term_name":"regulation of granulosa cell proliferation","termid":"GO:1904195"},{"relation_name":"positively_regulates","term_name":"granulosa cell proliferation","termid":"GO:1990739"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of granulosa cell proliferation","synonyms":[{"name":"activation of granulosa cell proliferation","type":"narrow"},{"name":"up regulation of granulosa cell proliferation","type":"exact"},{"name":"up-regulation of granulosa cell proliferation","type":"exact"},{"name":"upregulation of granulosa cell proliferation","type":"exact"}],"termid":"GO:1904197"}


id: GO:0033989
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.","definition_xrefs":["EC:4.2.1.107"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity","secondary_identifiers":["MetaCyc:4.2.1.107-RXN","Reactome:R-HSA-192331","Reactome:R-HSA-193535","RHEA:18933"],"synonyms":[{"name":"(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity","type":"related"},{"name":"(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity","type":"related"},{"name":"46 kDa hydratase 2 activity","type":"related"},{"name":"D-3-hydroxyacyl-CoA dehydratase activity","type":"broad"}],"termid":"GO:0033989"}


id: PBO:0056386
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAPK associated protein 1","termid":"PBO:0056386"}


id: PBO:0044820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 109C","termid":"PBO:0044820"}


id: PBO:0063364
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proprotein convertase subtilisin/kexin type 4","termid":"PBO:0063364"}


id: MONDO:0971143
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"malignant mesothelioma","termid":"MONDO:0006292"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"pleural mesothelioma in situ","secondary_identifiers":["Orphanet:675841"],"termid":"MONDO:0971143","xrefs":{"Monarch":{"xref_id":"0971143"}}}


id: PBO:0062925
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"purinergic receptor P2Y12","termid":"PBO:0062925"}


id: PBO:0091307
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human Rab6","termid":"PBO:0091307"}


id: PBO:0078999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Thr (anticodon AGT) 6-1","termid":"PBO:0078999"}


id: PBO:0049423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucuronidase beta","termid":"PBO:0049423"}


id: MONDO:0011676
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"PHACE is an acronym used to describe a syndrome characterized by the association of posterior fossa brain malformations, large facial haemangiomas, anatomical anomalies of the cerebral arteries, aortic coarctation and other cardiac anomalies, and eye abnormalities. Sternal anomalies are also sometimes present, and in these cases the syndrome is referred to as PHACES. Two additional manifestations have recently been added to the clinical spectrum of PHACE syndrome: stenosis of the vessels at the base of the skull and segmental longitudinal dilations of the internal carotid artery.","definition_xrefs":["Orphanet:42775"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete neurovascular malformation (obsolete MONDO:0015145)","termid":"MONDO:0015145"},{"relation_name":"excluded_subClassOf","term_name":"obsolete vascular tumor with associated anomalies (obsolete MONDO:0018718)","termid":"MONDO:0018718"},{"relation_name":"excluded_subClassOf","term_name":"obsolete genetic vascular tumor (obsolete MONDO:0018729)","termid":"MONDO:0018729"},{"relation_name":"excluded_subClassOf","term_name":"obsolete Moyamoya syndrome (obsolete MONDO:0018792)","termid":"MONDO:0018792"},{"relation_name":"excluded_subClassOf","term_name":"obsolete palpebral tumor with a vascular malformation (obsolete MONDO:0020182)","termid":"MONDO:0020182"},{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"is_a","term_name":"central nervous system malformation","termid":"MONDO:0020022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0020022"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005267","MONDO:0002320","MONDO:0020022"],"is_obsolete":false,"name":"PHACE syndrome","secondary_identifiers":["NORD:1927","MedDRA:10068032","GARD:8338","icd11.foundation:1825849023","MEDGEN:376231","OMIM:606519","UMLS:C1847874"],"synonyms":[{"name":"P-CIIS","type":"related"},{"name":"PHACE association","type":"related"},{"name":"Phaces association","type":"related"},{"name":"Posterior fossa brain malformations, hemangiomas of the face, arterial anomalies, cardiac anomalies, and eye abnormalities","type":"related"},{"name":"aortic aneurysm, giant congenital","type":"related"},{"name":"pascual-Castroviejo syndrome type 2","type":"exact"},{"name":"pascual-Castroviejo type II syndrome","type":"related"}],"termid":"MONDO:0011676","xrefs":{"Monarch":{"xref_id":"0011676"}}}


id: GO:0035501
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a MH1 (MAD homology 1) protein domain. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.","definition_xrefs":["Pfam:PF03165"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein domain specific binding","termid":"GO:0019904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"MH1 domain binding","synonyms":[{"name":"MAD homology 1 domain binding","type":"exact"}],"termid":"GO:0035501"}


id: PBO:0030662
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_transcriptional_response_to_pheromone","termid":"PBO:0030662"}


id: PBO:0034159
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_chromosomal_homology_relationship_with","termid":"PBO:0034159"}


id: GO:0033799
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.","definition_xrefs":["RHEA:25629"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-methyltransferase activity","termid":"GO:0008171"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0016741","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"myricetin 3'-O-methyltransferase activity","secondary_identifiers":["GO:0102437","KEGG_REACTION:R06815","MetaCyc:RXN-8451"],"synonyms":[{"name":"CrCOMT2","type":"related"},{"name":"S-adenosyl-L-methionine:myricetin O-methyltransferase activity","type":"related"},{"name":"flavonoid 3',5'-O-dimethyltransferase activity","type":"related"},{"name":"myricetin 3-O-methyltransferase activity","type":"related"}],"termid":"GO:0033799"}


id: MONDO:0008817
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive genetic disorder caused by mutations in the ENPP1 gene, encoding ectonucleotide pyrophosphatase/phosphodiesterase family member 1. The condition is characterized by calcification and narrowing of medium- and large-sized arteries, resulting in cardiovascular complications.","definition_xrefs":["NCIT:C128805"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arterial calcification of infancy","termid":"MONDO:0018870"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arterial calcification, generalized, of infancy, 1","secondary_identifiers":["OMIM:208000","UMLS:C4551985","MEDGEN:1631685"],"synonyms":[{"name":"ENPP1 arterial calcification of infancy","type":"exact"},{"name":"GACI1","type":"related"},{"name":"Gaci","type":"related"},{"name":"arterial calcification of infancy caused by mutation in ENPP1","type":"exact"},{"name":"arterial calcification, generalized, of infancy, 1","type":"exact"},{"name":"arterial calcification, generalized, of infancy, type 1","type":"exact"},{"name":"arterial calcification, idiopathic infantile","type":"related"},{"name":"arteriopathy, occlusive infantile","type":"related"},{"name":"coronary sclerosis, medial, of infancy","type":"related"},{"name":"generalised arterial calcification of infancy 1","type":"exact"},{"name":"generalized arterial calcification of infancy 1","type":"exact"},{"name":"idiopathic infantile arterial calcification","type":"related"}],"termid":"MONDO:0008817","xrefs":{"Monarch":{"xref_id":"0008817"}}}


id: GO:0060893
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.","definition_xrefs":["GOC:dph","GOC:sdb_2009","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epidermal cell fate specification","termid":"GO:0009957"},{"relation_name":"is_a","term_name":"cell fate specification involved in pattern specification","termid":"GO:0060573"},{"relation_name":"part_of","term_name":"limb epidermis stratification","termid":"GO:0060888"},{"relation_name":"part_of","term_name":"limb granular cell differentiation","termid":"GO:0060891"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"limb granular cell fate specification","termid":"GO:0060893"}


id: PBO:0060505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleosome assembly protein 1 like 5","termid":"PBO:0060505"}


id: PBO:0089267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein Nsa2","termid":"PBO:0089267"}


id: GO:0046352
data:
  {"annotated_genes":["SJAG_02131","SJAG_03824","SJAG_04859","SJAG_02949","SJAG_04301"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[101088,101089],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000025"},{"annotations":[99841],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005995"},{"annotations":[115567],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005987"},{"annotations":[110963],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005993"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disaccharide metabolic process","termid":"GO:0005984"},{"relation_name":"is_a","term_name":"oligosaccharide catabolic process","termid":"GO:0009313"}],"gene_count":5,"genes_by_uniquename":{"SJAG_02131":null,"SJAG_02949":null,"SJAG_03824":null,"SJAG_04301":null,"SJAG_04859":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"disaccharide catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"disaccharide breakdown","type":"exact"},{"name":"disaccharide catabolism","type":"exact"},{"name":"disaccharide degradation","type":"exact"}],"termid":"GO:0046352","terms_by_termid":{"GO:0000025":null,"GO:0005987":null,"GO:0005993":null,"GO:0005995":null}}


id: MONDO:0004639
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis usually of the right colon, cecum, terminal ileum, and appendix, possibly due to perinatal intestinal ischemia and bacterial invasion. Progression can lead to necrosis, perforation and/or scarring of the intestinal tract.","definition_xrefs":["NCIT:C84915"],"direct_ancestors":[{"relation_name":"is_a","term_name":"necrotizing enterocolitis","termid":"MONDO:0005313"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"perinatal necrotizing enterocolitis","secondary_identifiers":["SCTID:397729009","DOID:8677","UMLS:C4082937","MEDGEN:906305"],"synonyms":[{"name":"enterocolitis necrotizing","type":"broad"},{"name":"enterocolitis, necrotizing","type":"related"},{"name":"necrotizing enterocolitis","type":"broad"},{"name":"necrotizing enterocolitis in fetus or newborn","type":"exact"},{"name":"necrotizing enterocolitis in foetus or newborn","type":"exact"},{"name":"perinatal necrotising enterocolitis","type":"exact"},{"name":"pseudomembranous enterocolitis in newborn","type":"exact"}],"termid":"MONDO:0004639","xrefs":{"Monarch":{"xref_id":"0004639"}}}


id: GO:0006802
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The processes involved in the induction or activation of catalase, an enzyme that catalyzes the conversion of H2O2 into H2O.","definition_xrefs":["GOC:jl","PMID:11245904"],"gene_count":0,"genotype_count":0,"name":"obsolete catalase reaction (obsolete GO:0006802)","synonyms":[{"name":"catalase reaction","type":"exact"},{"name":"hydroperoxidase reaction","type":"related"}],"termid":"GO:0006802"}


id: MONDO:0013943
data:
  {"annotated_genes":["SJAG_03440"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86756],"is_not":false,"summary":null,"term":"MONDO:0013943"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"peroxisome biogenesis disorder","termid":"MONDO:0019234"},{"relation_name":"is_a","term_name":"peroxisome biogenesis disorder due to PEX16 defect","termid":"MONDO:0100269"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03440":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019053"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005244","MONDO:0005559","MONDO:0005066","MONDO:0019053"],"is_obsolete":false,"name":"peroxisome biogenesis disorder 8B","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C155763","MEDGEN:766874","DOID:0081437","GARD:15870","OMIM:614877","UMLS:C3553960"],"synonyms":[{"name":"PBD8B","type":"related"},{"name":"peroxisome biogenesis disorder 8B","type":"exact"},{"name":"peroxisome biogenesis disorder type 8B","type":"exact"}],"termid":"MONDO:0013943","terms_by_termid":{"MONDO:0013943":null},"xrefs":{"Monarch":{"xref_id":"0013943"}}}


id: PBO:0059543
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded tRNA-Lys (AAA/G)","termid":"PBO:0059543"}


id: MONDO:0012334
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant spastic paraplegia type 29 (SPG29) is a complex form of hereditary spastic paraplegia characterized by a spastic paraplegia presenting in adolescence, associated with the additional manifestations of sensorial hearing impairment due to auditory neuropathy and persistent vomiting due to a hiatal or paraesophageal hernia.","definition_xrefs":["Orphanet:101009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant complex spastic paraplegia","termid":"MONDO:0015087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0005559"],"is_obsolete":false,"name":"hereditary spastic paraplegia 29","secondary_identifiers":["GARD:9729","MEDGEN:346682","MESH:C536863","SCTID:733029008","OMIM:609727","UMLS:C1857855","DOID:0110780"],"synonyms":[{"name":"SPG29","type":"exact"},{"name":"autosomal dominant spastic paraplegia 29","type":"exact"},{"name":"autosomal dominant spastic paraplegia type 29","type":"related"},{"name":"hereditary spastic paraplegia type 29","type":"exact"},{"name":"spastic paraplegia 29","type":"related"},{"name":"spastic paraplegia 29, autosomal dominant","type":"related"}],"termid":"MONDO:0012334","xrefs":{"Monarch":{"xref_id":"0012334"}}}


id: PBO:0002326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAC domain protein","termid":"PBO:0002326"}


id: PBO:0034663
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-telomere_assembly_at_double-strand_break_site","termid":"PBO:0034663"}


id: GO:0004354
data:
  {"annotated_genes":["SJAG_03266"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[117177],"is_not":false,"summary":null,"term":"GO:0004354"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.","definition_xrefs":["EC:1.4.1.4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glutamate dehydrogenase [NAD(P)+] activity","termid":"GO:0004353"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03266":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"glutamate dehydrogenase (NADP+) activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:GLUTDEHYD-RXN","RHEA:11612"],"synonyms":[{"name":"L-glutamate dehydrogenase","type":"broad"},{"name":"L-glutamate:NADP+ oxidoreductase (deaminating)","type":"related"},{"name":"L-glutamic acid dehydrogenase activity","type":"related"},{"name":"NAD(P)-glutamate dehydrogenase activity","type":"related"},{"name":"NAD(P)H-dependent glutamate dehydrogenase activity","type":"related"},{"name":"dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))","type":"related"},{"name":"glutamic acid dehydrogenase","type":"broad"},{"name":"glutamic dehydrogenase activity","type":"broad"}],"termid":"GO:0004354","terms_by_termid":{"GO:0004354":null}}


id: MONDO:0014220
data:
  {"annotated_genes":["SJAG_04123"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85321],"is_not":false,"summary":null,"term":"MONDO:0014220"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"adenosine monophosphate deaminase deficiency","termid":"MONDO:0013028"},{"relation_name":"is_a","term_name":"myopathy","termid":"MONDO:0005336"},{"relation_name":"is_a","term_name":"hereditary skeletal muscle disorder","termid":"MONDO:0700223"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04123":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"myopathy due to myoadenylate deaminase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:615511","UMLS:C3714933","GARD:15248","NCIT:C157504","MEDGEN:811508"],"synonyms":[{"name":"AMP deaminase 1 deficiency","type":"related"},{"name":"AMP deaminase deficiency","type":"related"},{"name":"AMPD1 deficiency","type":"related"},{"name":"MMDD","type":"related"},{"name":"adenosine monophosphate deaminase 1 deficiency","type":"related"},{"name":"adenosine monophosphate deaminase deficiency","type":"related"},{"name":"adenosine monophosphate deaminase-1 deficiency, myopathy due to","type":"related"},{"name":"myoadenylate deaminase deficiency","type":"related"},{"name":"myoadenylate deaminase deficiency, myopathy due to","type":"related"},{"name":"myopathy due to myoadenylate deaminase deficiency","type":"exact"}],"termid":"MONDO:0014220","terms_by_termid":{"MONDO:0014220":null},"xrefs":{"Monarch":{"xref_id":"0014220"}}}


id: GO:0015467
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.","definition_xrefs":["GOC:mah","GOC:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inward rectifier potassium channel activity","termid":"GO:0005242"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"G-protein activated inward rectifier potassium channel activity","secondary_identifiers":["Reactome:R-HSA-1013020","GO:0015273"],"synonyms":[{"name":"G protein activated inward rectifier potassium channel activity","type":"exact"},{"name":"G protein enhanced inward rectifier potassium channel activity","type":"exact"},{"name":"G-protein enhanced inward rectifier potassium channel activity","type":"exact"},{"name":"G-protein-activated inward rectifier potassium channel activity","type":"exact"},{"name":"G-protein-enhanced inward rectifier potassium channel activity","type":"exact"}],"termid":"GO:0015467"}


id: PBO:0003790
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Hsp90 co-chaperone Cdc37","termid":"PBO:0003790"}


id: PBO:0005831
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prephenate dehydrogenase [NADP+] Tyr1 (predicted)","termid":"PBO:0005831"}


id: GO:0060140
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.","definition_xrefs":["GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by virus of syncytium formation via plasma membrane fusion (obsolete GO:0060140)","termid":"GO:0060140"}


id: PBO:0055166
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2587","termid":"PBO:0055166"}


id: GO:0061234
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glomerulus morphogenesis","termid":"GO:0072102"},{"relation_name":"part_of","term_name":"mesonephric glomerulus development","termid":"GO:0061224"},{"relation_name":"part_of","term_name":"mesonephric nephron morphogenesis","termid":"GO:0061228"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric glomerulus morphogenesis","termid":"GO:0061234"}


id: GO:0051283
data:
  {"annotated_genes":["SJAG_03850"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[108127],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061454"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular process","termid":"GO:0048523"},{"relation_name":"is_a","term_name":"regulation of sequestering of calcium ion","termid":"GO:0051282"},{"relation_name":"negatively_regulates","term_name":"sequestering of calcium ion","termid":"GO:0051208"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03850":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of sequestering of calcium ion","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"down regulation of sequestering of calcium ion","type":"exact"},{"name":"down-regulation of sequestering of calcium ion","type":"exact"},{"name":"downregulation of sequestering of calcium ion","type":"exact"},{"name":"inhibition of sequestering of calcium ion","type":"narrow"},{"name":"negative regulation of calcium ion (Ca2+) retention","type":"exact"},{"name":"negative regulation of calcium ion (Ca2+) sequestering","type":"exact"},{"name":"negative regulation of calcium ion (Ca2+) sequestration","type":"exact"},{"name":"negative regulation of calcium ion (Ca2+) storage","type":"exact"},{"name":"negative regulation of retention of calcium ion (Ca2+)","type":"exact"},{"name":"negative regulation of sequestering of calcium ion (Ca2+)","type":"exact"},{"name":"negative regulation of sequestration of calcium ion (Ca2+)","type":"exact"},{"name":"negative regulation of storage of calcium ion (Ca2+)","type":"exact"}],"termid":"GO:0051283","terms_by_termid":{"GO:0061454":null}}


id: GO:1901644
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of tRNA methylation in response to nitrogen starvation.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of tRNA methylation in response to nitrogen starvation (obsolete GO:1901644)","synonyms":[{"name":"activation of tRNA methylation in response to nitrogen starvation","type":"narrow"},{"name":"up regulation of tRNA methylation in response to nitrogen starvation","type":"exact"},{"name":"up-regulation of tRNA methylation in response to nitrogen starvation","type":"exact"},{"name":"upregulation of tRNA methylation in response to nitrogen starvation","type":"exact"}],"termid":"GO:1901644"}


id: PBO:0039855
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GTPase activating protein 21","termid":"PBO:0039855"}


id: GO:0062009
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.","definition_xrefs":["PMID:28784960"],"direct_ancestors":[{"relation_name":"is_a","term_name":"roof of mouth development","termid":"GO:0060021"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"secondary palate development","termid":"GO:0062009"}


id: PR:Q09705
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rsm24 gene.","definition_xrefs":["UniProtKB:Q09705","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"37S ribosomal protein S24, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC2F7.15","synonyms":[{"name":"Spom972h-rsm24","type":"exact"}],"termid":"PR:Q09705"}


id: GO:0030703
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.","definition_xrefs":["PMID:10822261","ISBN:0879694238","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"oogenesis","termid":"GO:0048477"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"eggshell formation","termid":"GO:0030703"}


id: GO:0031832
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 6 serotonin receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled serotonin receptor binding","termid":"GO:0031821"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005515","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"type 6 serotonin receptor binding","synonyms":[{"name":"5-hydroxytryptamine 6 receptor binding","type":"exact"},{"name":"type 6 serotonin receptor ligand","type":"narrow"}],"termid":"GO:0031832"}


id: PBO:0074610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 14B","termid":"PBO:0074610"}


id: PBO:0000814
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.8.-","termid":"PBO:0000814"}


id: MONDO:0011150
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"progeroid syndrome","termid":"MONDO:0015333"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"premature aging syndrome","termid":"MONDO:0019303"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019303"}],"interesting_parent_ids":["MONDO:0019303"],"is_obsolete":false,"name":"acroosteolysis-keloid-like lesions-premature aging syndrome","secondary_identifiers":["UMLS:C1866182","MESH:C536653","MEDGEN:400936","Orphanet:363665","GARD:4276","OMIM:601812"],"synonyms":[{"name":"PENTT","type":"related"},{"name":"Penttinen-aula syndrome","type":"related"},{"name":"premature ageing syndrome Penttinen type","type":"related"},{"name":"premature ageing syndrome, Penttinen type","type":"exact"},{"name":"premature aging syndrome Penttinen type","type":"related"},{"name":"premature aging syndrome, Penttinen type","type":"exact"},{"name":"prematurely aged appearance, delayed bone maturation, acro-osteolysis, and brachydactyly","type":"related"},{"name":"progeroid syndrome, Penttinen type","type":"related"}],"termid":"MONDO:0011150","xrefs":{"Monarch":{"xref_id":"0011150"}}}


id: PBO:0059268
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MRPL32 pseudogene 2","termid":"PBO:0059268"}


id: GO:0170043
data:
  {"annotated_genes":["SJAG_00635","SJAG_02972","SJAG_00695"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[97668],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019240"},{"annotations":[109959],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071269"},{"annotations":[111357],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006592"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids.","definition_xrefs":["GOC:ew"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic acid biosynthetic process","termid":"GO:0046394"},{"relation_name":"is_a","term_name":"non-proteinogenic amino acid metabolic process","termid":"GO:0170041"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00635":null,"SJAG_00695":null,"SJAG_02972":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"non-proteinogenic amino acid biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"non-proteinogenic amino acid anabolism","type":"exact"},{"name":"non-proteinogenic amino acid formation","type":"exact"},{"name":"non-proteinogenic amino acid synthesis","type":"exact"},{"name":"non-proteinogenic biosynthesis","type":"exact"}],"termid":"GO:0170043","terms_by_termid":{"GO:0006592":null,"GO:0019240":null,"GO:0071269":null}}


id: GO:2000496
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell population proliferation","termid":"GO:0008285"},{"relation_name":"is_a","term_name":"regulation of cell proliferation involved in compound eye morphogenesis","termid":"GO:2000495"},{"relation_name":"negatively_regulates","term_name":"cell proliferation involved in compound eye morphogenesis","termid":"GO:0035736"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell proliferation involved in compound eye morphogenesis","termid":"GO:2000496"}


id: PBO:0082318
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; promotes base excision repair in chromatin; essential helicase-related protein homologous to Snf2p","termid":"PBO:0082318"}


id: RO:0002292
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Inverse of 'expressed in'","direct_ancestors":[{"relation_name":"is_a","term_name":"genomically_related_to","termid":"RO:0002330"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"expresses","termid":"RO:0002292"}


id: PBO:0084143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"High-affinity glucose transporter of the major facilitator superfamily; expression is induced by low levels of glucose and repressed by high levels of glucose","termid":"PBO:0084143"}


id: PBO:0000312
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Proline","termid":"PBO:0000312"}


id: PBO:0003380
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA damage response protein (predicted)","termid":"PBO:0003380"}


id: PBO:0049509
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2A clustered histone 16","termid":"PBO:0049509"}


id: GO:0004638
data:
  {"annotated_genes":["SJAG_01081"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[113953],"is_not":false,"summary":null,"term":"GO:0004638"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2.","definition_xrefs":["EC:4.1.1.21","RHEA:10792"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01081":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"phosphoribosylaminoimidazole carboxylase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["KEGG_REACTION:R04209","Reactome:R-HSA-73806","MetaCyc:AIRCARBOXY-RXN"],"synonyms":[{"name":"1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity","type":"related"},{"name":"5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]","type":"related"},{"name":"5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity","type":"related"},{"name":"5-amino-1-ribosylimidazole 5-phosphate carboxylase activity","type":"related"},{"name":"5-phosphoribosyl-5-aminoimidazole carboxylase activity","type":"related"},{"name":"ADE2","type":"related"},{"name":"AIR carboxylase activity","type":"related"},{"name":"class II PurE","type":"related"}],"termid":"GO:0004638","terms_by_termid":{"GO:0004638":null}}


id: MONDO:0005028
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor.","definition_xrefs":["NCIT:C4025"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenocarcinoma","termid":"MONDO:0004970"},{"relation_name":"is_a","term_name":"carcinoma of esophagus","termid":"MONDO:0019086"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"esophageal adenocarcinoma","secondary_identifiers":["DOID:4914","UMLS:C0279628","EFO:0000478","MEDGEN:124636","ONCOTREE:ESCA","SCTID:276803003","GARD:16927","icd11.foundation:829915640","Orphanet:99976"],"synonyms":[{"name":"adenocarcinoma - esophagus","type":"exact"},{"name":"adenocarcinoma - oesophagus","type":"exact"},{"name":"adenocarcinoma of esophagus","type":"exact"},{"name":"adenocarcinoma of oesophagus","type":"exact"},{"name":"adenocarcinoma of the esophagus","type":"exact"},{"name":"adenocarcinoma of the oesophagus","type":"exact"},{"name":"esophageal adenocarcinoma","type":"exact"},{"name":"esophagus adenocarcinoma","type":"exact"},{"name":"oesophageal adenocarcinoma","type":"exact"},{"name":"oesophagus adenocarcinoma","type":"exact"}],"termid":"MONDO:0005028","xrefs":{"Monarch":{"xref_id":"0005028"}}}


id: MONDO:0013400
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic, developmental defect during embryogenesis disorder characterized by severe, early-onset, salt-wasting adrenal insufficiency and ambiguous/female external genitalia (irrespective of chromosomal sex) due to mutations in the <i>CYP11A1</i> gene. Milder cases may present delayed onset of adrenal gland dysfunction and genitalia phenotype may range from normal male to female in individuals with 46,XY karyotype. Imaging studies reveal hypoplastic/absent adrenal glands and biochemical findings include low serum cortisol, mineralocorticoids, androgens, and sodium, with elevated potassium levels.","definition_xrefs":["Orphanet:168558"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"chronic primary adrenal insufficiency","termid":"MONDO:0015129"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"adrenal gland disorder","termid":"MONDO:0005495"},{"relation_name":"is_a","term_name":"46,XY disorder of sex development","termid":"MONDO:0020040"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Congenital adrenal insufficiency with 46, XY sex reversal OR 46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency","secondary_identifiers":["NCIT:C131422","GARD:17033","MEDGEN:462405","OMIM:613743","MESH:C566130","DOID:0050546","UMLS:C3151055"],"synonyms":[{"name":"46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency","type":"related"},{"name":"46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency syndrome","type":"related"},{"name":"XY sex reversal-adrenal failure","type":"exact"},{"name":"XY sex reversal-adrenal failure syndrome","type":"exact"},{"name":"adrenal insufficiency, congenital, with 46,XY SEX reversal, partial or complete","type":"exact"},{"name":"adrenal insufficiency, congenital, with 46XY sex reversal, partial or complete","type":"exact"},{"name":"cholesterol side-chain cleavage deficiency","type":"exact"},{"name":"p450scc deficiency","type":"exact"}],"termid":"MONDO:0013400","xrefs":{"Monarch":{"xref_id":"0013400"}}}


id: PBO:0000596
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.4.2.28","termid":"PBO:0000596"}


id: MONDO:0004103
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A morphologic variant of papillary carcinoma of the thyroid gland characterized by the presence of tall malignant follicular cells, arranged in papillary and trabecular patterns. Necrotic changes and high mitotic activity are present.","definition_xrefs":["NCIT:C35558"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thyroid gland papillary carcinoma","termid":"MONDO:0005075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"tall cell variant thyroid gland papillary carcinoma","secondary_identifiers":["UMLS:C1336695","DOID:7089","MEDGEN:234416"],"synonyms":[{"name":"tall cell variant papillary carcinoma","type":"exact"},{"name":"tall cell variant thyroid gland papillary carcinoma","type":"exact"}],"termid":"MONDO:0004103","xrefs":{"Monarch":{"xref_id":"0004103"}}}


id: FYPO:0000918
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal citrate (Si)-synthase activity","termid":"FYPO:0000917"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000661","FYPO:0000652","FYPO:0000707","FYPO:0000654"],"is_obsolete":false,"name":"decreased citrate (Si)-synthase activity","synonyms":[{"name":"decreased citrate synthase activity","type":"broad"},{"name":"reduced citrate (Si)-synthase activity","type":"exact"}],"termid":"FYPO:0000918"}


id: GO:0000444
data:
  {"annotated_genes":["SJAG_02346","SJAG_00418","SJAG_03220","SJAG_01228"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[95060,98766,109766,109810],"is_not":false,"summary":null,"term":"GO:0000444"}]},"cv_name":"cellular_component","definition":"A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.","definition_xrefs":["PMID:16585270","PMID:14633972","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"outer kinetochore","termid":"GO:0000940"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00418":null,"SJAG_01228":null,"SJAG_02346":null,"SJAG_03220":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0000776"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005694"}],"interesting_parent_ids":["GO:0005694","GO:0005575","GO:0000776","GO:0032991"],"is_obsolete":false,"name":"MIS12/MIND type complex","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0000818"],"synonyms":[{"name":"MIND complex","type":"exact"},{"name":"Mis12 complex","type":"narrow"},{"name":"Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex","type":"related"},{"name":"nuclear MIS12/MIND complex","type":"related"}],"termid":"GO:0000444","terms_by_termid":{"GO:0000444":null}}


id: PBO:0049852
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HECT domain E3 ubiquitin protein ligase 1","termid":"PBO:0049852"}


id: MONDO:0971006
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"MHC class I deficiency","termid":"MONDO:0011476"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"MHC class I deficiency 1","secondary_identifiers":["OMIM:604571"],"termid":"MONDO:0971006","xrefs":{"Monarch":{"xref_id":"0971006"}}}


id: GO:0008845
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["PMID:12713806"],"gene_count":0,"genotype_count":0,"name":"obsolete endonuclease VIII activity (obsolete GO:0008845)","synonyms":[{"name":"endonuclease VIII activity","type":"exact"}],"termid":"GO:0008845"}


id: PR:O74840
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cue2 gene.","definition_xrefs":["UniProtKB:O74840","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Smr domain-containing protein C1235.03 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1235.03","synonyms":[{"name":"Spom972h-cue2","type":"exact"}],"termid":"PR:O74840"}


id: MONDO:0014131
data:
  {"annotated_genes":["SJAG_03158"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85547],"is_not":false,"summary":null,"term":"MONDO:0014131"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"diffuse palmoplantar keratoderma","termid":"MONDO:0017666"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03158":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0006025"],"is_obsolete":false,"name":"hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C3809160","GARD:17562","Orphanet:363523","OMIM:615328","MEDGEN:815490"],"synonyms":[{"name":"SHAHEEN syndrome","type":"related"},{"name":"SHNS","type":"related"}],"termid":"MONDO:0014131","terms_by_termid":{"MONDO:0014131":null},"xrefs":{"Monarch":{"xref_id":"0014131"}}}


id: PBO:0040758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brain expressed associated with NEDD4 1","termid":"PBO:0040758"}


id: PBO:0080321
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 85 pseudogene","termid":"PBO:0080321"}


id: PR:O94572
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dal52 gene.","definition_xrefs":["UniProtKB:O94572","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized transporter C1773.15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1773.15","synonyms":[{"name":"Spom972h-dal52","type":"exact"}],"termid":"PR:O94572"}


id: PBO:0013454
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trichostatin A partially suppresses rad1delta sensitivity to UV and hydroxyurea","termid":"PBO:0013454"}


id: GO:0010726
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.","definition_xrefs":["GOC:hjd","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of hydrogen peroxide metabolic process","termid":"GO:0010310"},{"relation_name":"is_a","term_name":"positive regulation of reactive oxygen species metabolic process","termid":"GO:2000379"},{"relation_name":"positively_regulates","term_name":"hydrogen peroxide metabolic process","termid":"GO:0042743"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of hydrogen peroxide metabolic process","synonyms":[{"name":"positive regulation of hydrogen peroxide metabolism","type":"exact"}],"termid":"GO:0010726"}


id: FYECO:0000010
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"The experimental conditions included the absence of a chemical.","definition_xrefs":["PomBase:al"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE FYECO:0000010 absence of chemical (obsolete FYECO:0000010)","termid":"FYECO:0000010"}


id: GO:0009010
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.","definition_xrefs":["EC:1.1.1.140"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"sorbitol-6-phosphate 2-dehydrogenase activity","secondary_identifiers":["RHEA:19837","MetaCyc:SORB6PDEHYDROG-RXN"],"synonyms":[{"name":"D-glucitol-6-phosphate dehydrogenase activity","type":"related"},{"name":"D-sorbitol 6-phosphate dehydrogenase activity","type":"related"},{"name":"D-sorbitol-6-phosphate dehydrogenase activity","type":"related"},{"name":"D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity","type":"related"},{"name":"glucitol-6-phosphate dehydrogenase activity","type":"related"},{"name":"ketosephosphate reductase activity","type":"related"},{"name":"sorbitol-6-P-dehydrogenase activity","type":"related"}],"termid":"GO:0009010"}


id: PBO:0074566
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA host gene 20","termid":"PBO:0074566"}


id: MONDO:0028618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete gastroenteric neuroendocrine neoplasm (obsolete MONDO:0028618)","secondary_identifiers":["Orphanet:481508"],"termid":"MONDO:0028618","xrefs":{"Monarch":{"xref_id":"0028618"}}}


id: GO:0009157
data:
  {"annotated_genes":["SJAG_04627","SJAG_03771","SJAG_04487"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[107839,88889],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006231"},{"annotations":[98491,107840],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006226"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside monophosphate biosynthetic process","termid":"GO:0009124"},{"relation_name":"is_a","term_name":"deoxyribonucleoside monophosphate metabolic process","termid":"GO:0009162"}],"gene_count":3,"genes_by_uniquename":{"SJAG_03771":null,"SJAG_04487":null,"SJAG_04627":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0055086","GO:0008150"],"is_obsolete":false,"name":"deoxyribonucleoside monophosphate biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"deoxyribonucleoside monophosphate anabolism","type":"exact"},{"name":"deoxyribonucleoside monophosphate biosynthesis","type":"exact"},{"name":"deoxyribonucleoside monophosphate formation","type":"exact"},{"name":"deoxyribonucleoside monophosphate synthesis","type":"exact"}],"termid":"GO:0009157","terms_by_termid":{"GO:0006226":null,"GO:0006231":null}}


id: PR:Q9US53
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- jmj2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9US53"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"jumonji/ARID domain-containing protein 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.05c","synonyms":[{"name":"Spom972h-jmj2","type":"exact"}],"termid":"PR:Q9US53"}


id: PBO:0069002
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 246, pseudogene","termid":"PBO:0069002"}


id: PBO:0054156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1523","termid":"PBO:0054156"}


id: PBO:0040205
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"astrotactin 1","termid":"PBO:0040205"}


id: PBO:0004701
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"splicing factor 3B (predicted)","termid":"PBO:0004701"}


id: PBO:0110190
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial membrane protein involved in heme biosynthesis, TMEM14 superfamily Aim19","termid":"PBO:0110190"}


id: MONDO:0008152
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Idiopathic multicentric osteolysis is a very rare syndrome characterized by progressive loss of bone, usually the capsal and tarsal bones, resulting in deformity and disability, as well as chronic renal failure in many cases. The bone and renal disorders are sometimes associated with intellectual deficit and facial abnormalities.","definition_xrefs":["Orphanet:2774"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary osteolysis","termid":"MONDO:0019707"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"multicentric carpo-tarsal osteolysis with or without nephropathy","secondary_identifiers":["DOID:0111534","MESH:C567171","OMIM:166300","UMLS:C2674705","MEDGEN:436237","GARD:3818","SCTID:766992008"],"synonyms":[{"name":"Carnevale canun Mendoza syndrome","type":"related"},{"name":"MCTO","type":"related"},{"name":"idiopathic multicentric osteolysis with or without nephropathy","type":"exact"},{"name":"multicentric carpo-tarsal osteolysis with or without nephropathy","type":"exact"},{"name":"multicentric carpotarsal osteolysis syndrome","type":"related"},{"name":"multicentric osteolysis nephropathy","type":"related"},{"name":"multicentric osteolysis, autosomal dominant","type":"related"},{"name":"osteolysis, hereditary, of carpal bones with or without nephropathy","type":"related"}],"termid":"MONDO:0008152","xrefs":{"Monarch":{"xref_id":"0008152"}}}


id: PBO:0038452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AARSD1 pseudogene 1","termid":"PBO:0038452"}


id: PBQ:0000001
data:
  {"annotation_feature_type":"gene","cv_name":"pb_quiescence","definition":"A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed.","definition_xrefs":["PomBase:jb","PomBase:mah"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell quiescence","synonyms":[{"name":"G0 phase","type":"related"},{"name":"cell cycle quiescence","type":"related"},{"name":"cellular quiescence","type":"exact"},{"name":"quiescence","type":"broad"}],"termid":"PBQ:0000001"}


id: GO:0016217
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+.","definition_xrefs":["MetaCyc:R465-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on acid halide bonds, in C-halide compounds","termid":"GO:0019120"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"N-ethylammeline chlorohydrolase activity","termid":"GO:0016217"}


id: PBO:0044108
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cancer/testis associated 62","termid":"PBO:0044108"}


id: MONDO:0012757
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome is characterized by immune deficiency, gonadal dysgenesis and fatal lung fibrosis. So far, it has been described in two sisters born to consanguineous parents. Both karyotypes were normal female (46,XX). No genetic anomalies could be identified by comparative genome hybridization analysis of their genomes or by analysis of genes known to be associated with these types of anomalies.","definition_xrefs":["Orphanet:137631"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary interstitial lung disease specific to childhood","termid":"MONDO:0017015"},{"relation_name":"is_a","term_name":"T-B+ severe combined immunodeficiency","termid":"MONDO:0044200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome","secondary_identifiers":["OMIM:611926","UMLS:C3150156","MEDGEN:461506","SCTID:721977007","GARD:16947"],"synonyms":[{"name":"immunodeficiency, ovarian dysgenesis, and pulmonary fibrosis","type":"related"}],"termid":"MONDO:0012757","xrefs":{"Monarch":{"xref_id":"0012757"}}}


id: PBO:0026990
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_mitochondrion","termid":"PBO:0026990"}


id: GO:0001216
data:
  {"annotated_genes":["SJAG_03735","SJAG_00698","SJAG_04009","SJAG_01062","SJAG_00802","SJAG_04249","SJAG_05247","SJAG_02810","SJAG_04813","SJAG_02730","SJAG_01243","SJAG_03879","SJAG_02326","SJAG_02311","SJAG_04749","SJAG_01694","SJAG_03143","SJAG_04855","SJAG_03538","SJAG_04036","SJAG_01916","SJAG_04839","SJAG_03241","SJAG_00210","SJAG_00987","SJAG_02252","SJAG_00266","SJAG_02218","SJAG_01307","SJAG_00693","SJAG_02406","SJAG_03519","SJAG_02472","SJAG_03346","SJAG_05288","SJAG_00163","SJAG_04092","SJAG_01583","SJAG_04712","SJAG_05153","SJAG_03484","SJAG_03183","SJAG_04388"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[108812],"is_not":false,"summary":null,"term":"GO:0001216"},{"annotations":[105312,101770,103930,87973,108648,111371,113125,97926,88308,88978,99003,92802,107044,108266,91423,111332,94247,109153,104257,113530,115917,116929,96802,95789,89609,87547,99305,97613,115519,114026,92259,99990,111372,108508,108647,87113,110177,117503,106522,87476,88554,93217,107442,105579,95196],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001228"}]},"cv_name":"molecular_function","definition":"A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.","definition_xrefs":["GOC:txnOH-2018"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA-binding transcription factor activity","termid":"GO:0003700"}],"gene_count":43,"genes_by_uniquename":{"SJAG_00163":null,"SJAG_00210":null,"SJAG_00266":null,"SJAG_00693":null,"SJAG_00698":null,"SJAG_00802":null,"SJAG_00987":null,"SJAG_01062":null,"SJAG_01243":null,"SJAG_01307":null,"SJAG_01583":null,"SJAG_01694":null,"SJAG_01916":null,"SJAG_02218":null,"SJAG_02252":null,"SJAG_02311":null,"SJAG_02326":null,"SJAG_02406":null,"SJAG_02472":null,"SJAG_02730":null,"SJAG_02810":null,"SJAG_03143":null,"SJAG_03183":null,"SJAG_03241":null,"SJAG_03346":null,"SJAG_03484":null,"SJAG_03519":null,"SJAG_03538":null,"SJAG_03735":null,"SJAG_03879":null,"SJAG_04009":null,"SJAG_04036":null,"SJAG_04092":null,"SJAG_04249":null,"SJAG_04388":null,"SJAG_04712":null,"SJAG_04749":null,"SJAG_04813":null,"SJAG_04839":null,"SJAG_04855":null,"SJAG_05153":null,"SJAG_05247":null,"SJAG_05288":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003700"},{"rel_name":"is_a","termid":"GO:0140110"}],"interesting_parent_ids":["GO:0003674","GO:0140110","GO:0003700"],"is_obsolete":false,"name":"DNA-binding transcription activator activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0001140","GO:0001215"],"synonyms":[{"name":"bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription","type":"related"},{"name":"bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding","type":"narrow"},{"name":"bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding","type":"narrow"},{"name":"metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription","type":"narrow"},{"name":"sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription","type":"narrow"},{"name":"transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding","type":"narrow"},{"name":"transcriptional activator activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding","type":"related"}],"termid":"GO:0001216","terms_by_termid":{"GO:0001216":null,"GO:0001228":null}}


id: PBO:0013774
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mst2 histone acetytransferase acytyltransferase complex, predicted phosphoric monoester hydrolase Ptf1","termid":"PBO:0013774"}


id: GO:0051549
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of keratinocyte migration.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of epithelial cell migration","termid":"GO:0010634"},{"relation_name":"is_a","term_name":"regulation of keratinocyte migration","termid":"GO:0051547"},{"relation_name":"positively_regulates","term_name":"keratinocyte migration","termid":"GO:0051546"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of keratinocyte migration","synonyms":[{"name":"activation of keratinocyte migration","type":"narrow"},{"name":"stimulation of keratinocyte migration","type":"narrow"},{"name":"up regulation of keratinocyte migration","type":"exact"},{"name":"up-regulation of keratinocyte migration","type":"exact"},{"name":"upregulation of keratinocyte migration","type":"exact"}],"termid":"GO:0051549"}


id: PBO:0036174
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_glutamate_dehydrogenase_(NADP+)_activity_during_cellular_response_to_iron_ion_starvation","termid":"PBO:0036174"}


id: PBO:0028111
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_bis(5'-adenosyl)-hexaphosphatase_activity","termid":"PBO:0028111"}


id: GO:0150022
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure.","definition_xrefs":["PMID:22683681","GOC:bc","GOC:aruk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dendrite development","termid":"GO:0016358"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"apical dendrite development","termid":"GO:0150022"}


id: PBO:0002126
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in the current viewer tco1 gene is hidden behind SPNCRNA.600","termid":"PBO:0002126"}


id: GO:1902414
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location within a cell junction.","definition_xrefs":["PMID:18332111","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization","termid":"GO:0008104"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to cell junction","synonyms":[{"name":"protein localisation in cell junction","type":"exact"},{"name":"protein localisation to cell junction","type":"exact"},{"name":"protein localization in cell junction","type":"exact"}],"termid":"GO:1902414"}


id: FYPO:0005786
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing extends for a shorter distance from the breaks site than normal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.","definition_xrefs":["PomBase:mah","GO:0000729","PMID:27729451"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal double-strand break processing","termid":"FYPO:0002553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0000298","FYPO:0001320","FYPO:0000293"],"is_obsolete":false,"name":"decreased spatial extent of double-strand break processing","synonyms":[{"name":"decreased spatial extent of DSB processing","type":"exact"},{"name":"decreased spatial extent of double-strand break processing during mitotic cell cycle","type":"related"},{"name":"decreased spatial extent of double-strand break processing during vegetative growth","type":"exact"},{"name":"decreased spatial extent of double-strand break resection","type":"exact"},{"name":"reduced spatial extent of double-strand break processing","type":"exact"}],"termid":"FYPO:0005786"}


id: MONDO:0005674
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint.","definition_xrefs":["NCIT:C121932"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bone sarcoma","termid":"MONDO:0021054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"bone giant cell tumor","secondary_identifiers":["DOID:4305","HP:0011847","MEDGEN:64624","ONCOTREE:GCTB","EFO:0007176","MESH:D018212","SCTID:697970009","MONDO:0018219","GARD:13046","UMLS:C0206638","Orphanet:363976"],"synonyms":[{"name":"GCT of bone","type":"exact"},{"name":"Osteoclastoma, benign","type":"exact"},{"name":"benign bone giant cell tumor","type":"exact"},{"name":"benign bone giant cell tumour","type":"exact"},{"name":"giant cell myeloma","type":"related"},{"name":"giant cell neoplasm of bone","type":"exact"},{"name":"giant cell tumor of bone","type":"exact"},{"name":"giant cell tumor of bone (morphologic abnormality)","type":"exact"},{"name":"giant cell tumor of bone NOS (morphologic abnormality)","type":"exact"},{"name":"giant cell tumor of the bone","type":"exact"},{"name":"giant cell tumor, benign","type":"exact"},{"name":"giant cell tumour of bone","type":"exact"},{"name":"giant cell tumour of bone (morphologic abnormality)","type":"exact"},{"name":"giant cell tumour of bone NOS (morphologic abnormality)","type":"exact"},{"name":"giant cell tumour of the bone","type":"exact"},{"name":"osteoclastoma","type":"related"}],"termid":"MONDO:0005674","xrefs":{"Monarch":{"xref_id":"0005674"}}}


id: GO:0030132
data:
  {"annotated_genes":["SJAG_00104","SJAG_00800","SJAG_02805","SJAG_01167"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[95767,111041,111100,107790],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030122"}]},"cv_name":"cellular_component","definition":"The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"clathrin coat","termid":"GO:0030118"},{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"},{"relation_name":"part_of","term_name":"clathrin-coated pit","termid":"GO:0005905"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00104":null,"SJAG_00800":null,"SJAG_01167":null,"SJAG_02805":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005737","GO:0032991","GO:0005575","GO:0005886"],"is_obsolete":false,"name":"clathrin coat of coated pit","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0030132","terms_by_termid":{"GO:0030122":null}}


id: PBO:0061016
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleolar protein interacting with the FHA domain of MKI67","termid":"PBO:0061016"}


id: MONDO:1012417
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"persistent right aortic arch with subclavian artery and ligamentum arteriosum, non-human animal","termid":"MONDO:1011649"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"persistent right aortic arch with subclavian artery and ligamentum arteriosum, dog","secondary_identifiers":["OMIA:001570-9615"],"termid":"MONDO:1012417","xrefs":{"Monarch":{"xref_id":"1012417"}}}


id: GO:0014056
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.","definition_xrefs":["GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synaptic transmission, cholinergic","termid":"GO:0032222"},{"relation_name":"is_a","term_name":"regulation of neurotransmitter secretion","termid":"GO:0046928"},{"relation_name":"is_a","term_name":"regulation of amine transport","termid":"GO:0051952"},{"relation_name":"regulates","term_name":"acetylcholine secretion, neurotransmission","termid":"GO:0014055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of acetylcholine secretion, neurotransmission","termid":"GO:0014056"}


id: GO:0033852
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.","definition_xrefs":["EC:2.6.1.26","RHEA:19133"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transaminase activity","termid":"GO:0008483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016769"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016769"],"is_obsolete":false,"name":"thyroid-hormone transaminase activity","secondary_identifiers":["KEGG_REACTION:R03952","MetaCyc:THYROID-HORMONE-AMINOTRANSFERASE-RXN"],"synonyms":[{"name":"3,5-dinitrotyrosine aminotransferase activity","type":"related"},{"name":"3,5-dinitrotyrosine transaminase activity","type":"related"},{"name":"L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity","type":"related"},{"name":"thyroid hormone aminotransferase activity","type":"related"},{"name":"thyroid-hormone aminotransferase activity","type":"related"}],"termid":"GO:0033852"}


id: MONDO:0002837
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A poorly differentiated transitional cell carcinoma characterized by the presence of malignant cells with spindle cell morphologic features.","definition_xrefs":["NCIT:C4120"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sarcomatoid carcinoma","termid":"MONDO:0006406"},{"relation_name":"is_a","term_name":"transitional cell carcinoma","termid":"MONDO:0006474"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"sarcomatoid transitional cell carcinoma","secondary_identifiers":["ICDO:8122/3","UMLS:C0334271","MEDGEN:83120","DOID:4014"],"synonyms":[{"name":"sarcomatoid transitional cell carcinoma","type":"exact"},{"name":"transitional cell carcinoma, sarcomatoid","type":"exact"},{"name":"transitional cell spindle cell carcinoma","type":"exact"},{"name":"transitional spindle cell carcinoma","type":"exact"}],"termid":"MONDO:0002837","xrefs":{"Monarch":{"xref_id":"0002837"}}}


id: PBO:0086399
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative dityrosine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; required for spore wall synthesis; sequence similarity to QDR1 and QDR3, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expressed during sporulation","termid":"PBO:0086399"}


id: GO:0002522
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.","definition_xrefs":["PMID:7507411","PMID:14680625","PMID:8600538","GOC:add","PMID:14708592","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune effector process","termid":"GO:0002252"},{"relation_name":"is_a","term_name":"leukocyte migration","termid":"GO:0050900"},{"relation_name":"part_of","term_name":"immune response","termid":"GO:0006955"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"leukocyte migration involved in immune response","synonyms":[{"name":"immune cell migration during immune response","type":"exact"},{"name":"immune cell trafficking during immune response","type":"exact"},{"name":"leucocyte migration during immune response","type":"exact"},{"name":"leucocyte trafficking during immune response","type":"exact"},{"name":"leukocyte trafficking during immune response","type":"exact"}],"termid":"GO:0002522"}


id: FYPO:0002947
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the size, shape, or structure of the fungal-type cell wall is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell wall","termid":"FYPO:0002946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002946"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0002946"],"is_obsolete":false,"name":"abnormal cell wall morphology","synonyms":[{"name":"cell wall morphology: abnormal","type":"related"}],"termid":"FYPO:0002947"}


id: PR:000050456
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An RNA-binding protein rnc1 (Schizosaccharomyces pombe) that has not been phosphorylated at positions equivalent to Thr-45, Thr-50, Thr-171, Thr-177, Ser-278, and Ser-286 of the amino acid sequence represented by UniProtKB:O74919. Example: UniProtKB:O74919, Thr-45/Thr-50/Thr-171/Thr-177/Ser-278/Ser-286, PR:000026291.","definition_xrefs":["PRO:DAN","PMID:31911490","PomBase:VW"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA-binding protein rnc1 (Schizosaccharomyces pombe)","termid":"PR:000050452"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rnc1/UnPhos:(T45,T50,T171,T177,S278,S286)","pombase_gene_id":"SPCC757.09c","synonyms":[{"name":"PomBase_original_PRO_term_name: RNA-binding protein rnc1 unphosphorylated 2 (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-rnc1/UnPhos:2","type":"exact"},{"name":"UniProtKB:O74919, Thr-45/Thr-50/Thr-171/Thr-177/Ser-278/Ser-286, PR:000026291","type":"narrow"},{"name":"rnc1/UnPhos:(T45,T50,T171,T177,S278,S286)","type":"exact"}],"termid":"PR:000050456"}


id: PBO:0087000
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho-family GTPase interacting protein and Cdc42p effector; required with Gic1p for cell polarity establishment and initiation of budding; involved in recruitment of septins to the presumptive bud site; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region; gic1 gic2 double mutants are defective for polarizing Cdc42p at elevated temperature, so may function both up- and downstream of Cdc42p; regulates mitotic exit","termid":"PBO:0087000"}


id: MONDO:0030407
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare disease with Cushing syndrome as a major feature (obsolete MONDO:0030407)","termid":"MONDO:0030407","xrefs":{"Monarch":{"xref_id":"0030407"}}}


id: GO:0000481
data:
  {"annotated_genes":["SJAG_04433"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89047],"is_not":false,"summary":null,"term":"GO:0000481"}]},"cv_name":"biological_process","definition":"Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA processing","termid":"GO:0006364"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04433":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0042254"}],"interesting_parent_ids":["GO:0044085","GO:0042254","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"maturation of 5S rRNA","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0000481","terms_by_termid":{"GO:0000481":null}}


id: PBO:0060139
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial tRNA translation optimization 1","termid":"PBO:0060139"}


id: GO:0070012
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.","definition_xrefs":["ISBN:0198506732","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endopeptidase activity","termid":"GO:0004175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0008233"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0140096","GO:0008233","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"oligopeptidase activity","termid":"GO:0070012"}


id: PBO:0072741
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S100 calcium binding protein A6","termid":"PBO:0072741"}


id: PBO:0060944
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear factor I A","termid":"PBO:0060944"}


id: MONDO:0017653
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete epilepsy and/or ataxia with myoclonus as major feature (obsolete MONDO:0017653)","secondary_identifiers":["Orphanet:306756"],"termid":"MONDO:0017653","xrefs":{"Monarch":{"xref_id":"0017653"}}}


id: PBO:0076988
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THAP domain containing 5 pseudogene 1","termid":"PBO:0076988"}


id: GO:1900901
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of metabolic process","termid":"GO:0009893"},{"relation_name":"is_a","term_name":"regulation of heptadecane metabolic process","termid":"GO:1900899"},{"relation_name":"positively_regulates","term_name":"heptadecane metabolic process","termid":"GO:1900635"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of heptadecane metabolic process","synonyms":[{"name":"activation of heptadecane metabolic process","type":"narrow"},{"name":"activation of heptadecane metabolism","type":"narrow"},{"name":"positive regulation of heptadecane metabolism","type":"related"},{"name":"up regulation of heptadecane metabolic process","type":"exact"},{"name":"up regulation of heptadecane metabolism","type":"related"},{"name":"up-regulation of heptadecane metabolic process","type":"exact"},{"name":"up-regulation of heptadecane metabolism","type":"related"},{"name":"upregulation of heptadecane metabolic process","type":"exact"},{"name":"upregulation of heptadecane metabolism","type":"related"}],"termid":"GO:1900901"}


id: PBO:0069834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1120, pseudogene","termid":"PBO:0069834"}


id: GO:1990117
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.","definition_xrefs":["PMID:15214043","GOC:BHF","GOC:mtg_apoptosis","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"B cell receptor signaling pathway","termid":"GO:0050853"},{"relation_name":"is_a","term_name":"extrinsic apoptotic signaling pathway","termid":"GO:0097191"},{"relation_name":"part_of","term_name":"B cell apoptotic process","termid":"GO:0001783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"B cell receptor apoptotic signaling pathway","synonyms":[{"name":"B cell receptor extrinsic apoptotic signaling pathway","type":"exact"},{"name":"extrinsic apoptotic signaling pathway via B cell antigen receptor","type":"related"},{"name":"extrinsic apoptotic signaling pathway via BCR","type":"related"}],"termid":"GO:1990117"}


id: PBO:0055771
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ligand of numb-protein X 1","termid":"PBO:0055771"}


id: GO:0046730
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The induction by a virus of an immune response in the host organism.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete induction by virus of host immune response (obsolete GO:0046730)","synonyms":[{"name":"activation of host immune response by virus","type":"exact"},{"name":"active induction of host immune response by virus","type":"related"},{"name":"active viral induction of host immune response","type":"related"},{"name":"passive activation of host immune response by virus","type":"narrow"},{"name":"passive induction of cell-mediated immune response in host by virus","type":"narrow"},{"name":"passive induction of host cell-mediated immune response by virus","type":"narrow"},{"name":"passive induction of host humoral immune response by virus","type":"narrow"},{"name":"passive induction of host immune response by virus","type":"narrow"},{"name":"passive induction of host innate immune response by virus","type":"narrow"},{"name":"passive induction of humoral immune response in host by virus","type":"narrow"},{"name":"passive induction of innate immune response in host by virus","type":"narrow"},{"name":"passive viral activation of cell-mediated immune response in host","type":"narrow"},{"name":"passive viral activation of humoral immune response in host","type":"narrow"},{"name":"passive viral activation of innate immune response in host","type":"narrow"},{"name":"passive viral induction of cell-mediated immune response in host","type":"narrow"},{"name":"passive viral induction of host immune response","type":"narrow"},{"name":"passive viral induction of humoral immune response in host","type":"narrow"},{"name":"passive viral induction of innate immune response in host","type":"narrow"}],"termid":"GO:0046730"}


id: GO:1903764
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane.","definition_xrefs":["PMID:19646991","GO_REF:0000058","GOC:mtg_cardiac_conduct_nov11","GOC:rl","GOC:BHF","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of potassium ion transmembrane transport","termid":"GO:1901379"},{"relation_name":"regulates","term_name":"potassium ion export across plasma membrane","termid":"GO:0097623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"regulation of potassium ion export across plasma membrane","secondary_identifiers":["GO:1902302"],"synonyms":[{"name":"regulation of potassium export","type":"broad"},{"name":"regulation of potassium export across plasma membrane","type":"broad"},{"name":"regulation of potassium ion export","type":"broad"}],"termid":"GO:1903764"}


id: PBO:0005640
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae COX18","termid":"PBO:0005640"}


id: PR:O94347
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ATP-dependent (S)-NAD(P)H-hydrate dehydratase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent (S)-NAD(P)H-hydrate dehydratase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC61.03","secondary_identifiers":["UniProtKB:O94347"],"synonyms":[{"name":"ATP-dependent NAD(P)HX dehydratase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-CARKD","type":"exact"}],"termid":"PR:O94347"}


id: MONDO:0001713
data:
  {"annotated_genes":["SJAG_02335","SJAG_02046","SJAG_04204","SJAG_02340","SJAG_03762","SJAG_00468","SJAG_01296","SJAG_01840","SJAG_04478","SJAG_02358","SJAG_02556","SJAG_01410","SJAG_02708","SJAG_00166","SJAG_03919","SJAG_02339","SJAG_00749","SJAG_03254","SJAG_04414","SJAG_02904","SJAG_00465","SJAG_02280","SJAG_05180","SJAG_02597","SJAG_02749","SJAG_04066","SJAG_04746","SJAG_01588","SJAG_01621","SJAG_02894","SJAG_02585","SJAG_00921","SJAG_00611","SJAG_01512","SJAG_04695","SJAG_01366","SJAG_02802","SJAG_03335","SJAG_01568","SJAG_04168"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85836],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013851"},{"annotations":[85048,85049],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007110"},{"annotations":[85821,85822],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013217"},{"annotations":[86711],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013964"},{"annotations":[85346,85345],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014245"},{"annotations":[85921],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014394"},{"annotations":[84857],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010493"},{"annotations":[85950,85951],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011639"},{"annotations":[86346,86345],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044309"},{"annotations":[86349],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044310"},{"annotations":[85579,85580],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032668"},{"annotations":[85581],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032669"},{"annotations":[85583,85584],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032670"},{"annotations":[85300],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0031071"},{"annotations":[85380,85379],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012529"},{"annotations":[86283,86284],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012924"},{"annotations":[86281,86282],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012925"},{"annotations":[86299,86300],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012937"},{"annotations":[86298,86297],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012938"},{"annotations":[86301],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012939"},{"annotations":[85823,85824],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013216"},{"annotations":[85847],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013248"},{"annotations":[86271],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013499"},{"annotations":[84552],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014108"},{"annotations":[86526],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014986"},{"annotations":[86530],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014987"},{"annotations":[86527],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014985"}]},"cv_name":"mondo","definition":"An inborn condition characterized by deficiencies of red cell precursors that sometimes also includes leukopenia and thrombocytopenia.","definition_xrefs":["MESH:D029502"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"idiopathic aplastic anemia","termid":"MONDO:0012197"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"aplastic anemia","termid":"MONDO:0015909"}],"gene_count":40,"genes_by_uniquename":{"SJAG_00166":null,"SJAG_00465":null,"SJAG_00468":null,"SJAG_00611":null,"SJAG_00749":null,"SJAG_00921":null,"SJAG_01296":null,"SJAG_01366":null,"SJAG_01410":null,"SJAG_01512":null,"SJAG_01568":null,"SJAG_01588":null,"SJAG_01621":null,"SJAG_01840":null,"SJAG_02046":null,"SJAG_02280":null,"SJAG_02335":null,"SJAG_02339":null,"SJAG_02340":null,"SJAG_02358":null,"SJAG_02556":null,"SJAG_02585":null,"SJAG_02597":null,"SJAG_02708":null,"SJAG_02749":null,"SJAG_02802":null,"SJAG_02894":null,"SJAG_02904":null,"SJAG_03254":null,"SJAG_03335":null,"SJAG_03762":null,"SJAG_03919":null,"SJAG_04066":null,"SJAG_04168":null,"SJAG_04204":null,"SJAG_04414":null,"SJAG_04478":null,"SJAG_04695":null,"SJAG_04746":null,"SJAG_05180":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0002280","MONDO:0005570"],"is_obsolete":false,"name":"inherited aplastic anemia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:1342","MEDGEN:1826154","Orphanet:68383","ICD10CM:D61.0","ICD9:284.0","NANDO:1200302","UMLS:C5681331","NANDO:2201275","SCTID:28975000","ICD9:284.09","GARD:18889"],"synonyms":[{"name":"congenital aplastic anaemia","type":"related"},{"name":"congenital aplastic anemia","type":"related"},{"name":"congenital hypoplastic anaemia","type":"related"},{"name":"congenital hypoplastic anemia","type":"related"},{"name":"constitutional aplastic anaemia","type":"exact"},{"name":"constitutional aplastic anemia","type":"exact"},{"name":"hereditary aplastic anaemia","type":"exact"},{"name":"hereditary aplastic anemia","type":"exact"},{"name":"hypoplastic anaemia - familial","type":"related"},{"name":"hypoplastic anemia - familial","type":"related"},{"name":"rare constitutional aplastic anaemia","type":"narrow"},{"name":"rare constitutional aplastic anemia","type":"narrow"}],"termid":"MONDO:0001713","terms_by_termid":{"MONDO:0007110":null,"MONDO:0010493":null,"MONDO:0011639":null,"MONDO:0012529":null,"MONDO:0012924":null,"MONDO:0012925":null,"MONDO:0012937":null,"MONDO:0012938":null,"MONDO:0012939":null,"MONDO:0013216":null,"MONDO:0013217":null,"MONDO:0013248":null,"MONDO:0013499":null,"MONDO:0013851":null,"MONDO:0013964":null,"MONDO:0014108":null,"MONDO:0014245":null,"MONDO:0014394":null,"MONDO:0014985":null,"MONDO:0014986":null,"MONDO:0014987":null,"MONDO:0031071":null,"MONDO:0032668":null,"MONDO:0032669":null,"MONDO:0032670":null,"MONDO:0044309":null,"MONDO:0044310":null},"xrefs":{"Monarch":{"xref_id":"0001713"}}}


id: PBO:0090613
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication checkpoint kinase Cds1","termid":"PBO:0090613"}


id: PBO:0000621
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar amino acid efflux transporter Atg22","termid":"PBO:0000621"}


id: GO:0046598
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of viral entry into host cell","termid":"GO:0046596"},{"relation_name":"is_a","term_name":"positive regulation by symbiont of entry into host","termid":"GO:0075294"},{"relation_name":"is_a","term_name":"positive regulation of viral life cycle","termid":"GO:1903902"},{"relation_name":"positively_regulates","term_name":"symbiont entry into host cell","termid":"GO:0046718"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of viral entry into host cell","synonyms":[{"name":"positive regulation of viral penetration into host cell","type":"exact"}],"termid":"GO:0046598"}


id: SOFP:feature_property
data:
  {"annotation_feature_type":"gene","cv_name":"feature_property","definition":"A general purpose relation between a biological feature and some value","definition_xrefs":["so:cjm"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"feature_property","termid":"SOFP:feature_property"}


id: PBO:0063932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pim-1 proto-oncogene, serine/threonine kinase","termid":"PBO:0063932"}


id: GO:0005602
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"extracellular region","termid":"GO:0005576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005576"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005576"],"is_obsolete":false,"name":"complement component C1 complex","synonyms":[{"name":"complement component C1q complex","type":"narrow"}],"termid":"GO:0005602"}


id: GO:0015125
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transmembrane transporter activity","termid":"GO:0008028"},{"relation_name":"is_a","term_name":"lipid transmembrane transporter activity","termid":"GO:0170055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"bile acid transmembrane transporter activity","secondary_identifiers":["Reactome:R-HSA-194079","Reactome:R-HSA-9733964","Reactome:R-HSA-194083","Reactome:R-HSA-194130","Reactome:R-HSA-5661198","Reactome:R-HSA-5661184"],"termid":"GO:0015125"}


id: GO:0000085
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.","definition_xrefs":["GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G2 phase","termid":"GO:0051319"},{"relation_name":"part_of","term_name":"mitotic interphase","termid":"GO:0051329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0051329"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051329","GO:0008150"],"is_obsolete":false,"name":"mitotic G2 phase","synonyms":[{"name":"G2 phase of mitotic cell cycle","type":"exact"}],"termid":"GO:0000085"}


id: MOD:00276
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively results from forming an adduct between two cysteine residues, a lysine residue, and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron.","definition_xrefs":["PubMed:9237682","RESID:AA0271","PubMed:12709052"],"direct_ancestors":[{"relation_name":"is_a","term_name":"porphyrin modified residue","termid":"MOD:00699"},{"relation_name":"is_a","term_name":"metal or metal cluster coordinated L-cysteine residue","termid":"MOD:02067"},{"relation_name":"is_a","term_name":"metal or metal cluster coordinated L-lysine residue","termid":"MOD:02074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"heme P460-bis-L-cysteine-L-lysine","synonyms":[{"name":"(19S,20S)-[7,12-bis((S)-1-[((R)-2-amino-2-carboxy)ethylsulfanyl]ethyl)-20-([(S)-5-amino-5-carboxypentyl]amino)-3,8,13,17-tetramethyl-21H,23H-19,20-dihydroporphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate","type":"exact"},{"name":"BINDING Heme (covalent; via 3 links)","type":"exact"},{"name":"bis(S-cysteinyl)-N6-lysino-heme","type":"exact"},{"name":"heme P460-bis-L-cysteine-L-lysine","type":"exact"}],"termid":"MOD:00276"}


id: GO:0033750
data:
  {"annotated_genes":["SJAG_01339","SJAG_02210","SJAG_01338","SJAG_04148","SJAG_02250","SJAG_02274","SJAG_03299","SJAG_04721","SJAG_01449","SJAG_03729","SJAG_04940","SJAG_03012","SJAG_04379","SJAG_04308","SJAG_01013","SJAG_00753","SJAG_02757","SJAG_00178","SJAG_01391","SJAG_03882","SJAG_01065","SJAG_03593","SJAG_00471","SJAG_01358","SJAG_03719"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[99138,115673,105215,89292,90593,101365,102484,117117],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000055"},{"annotations":[96576,99316,90594,102485],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000056"},{"annotations":[95627,93493,94482,109883,110894,91230,96569,100883,105627,88523,102141,115608,103428,99906,104855],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000054"}]},"cv_name":"biological_process","definition":"A process in which a ribosome is transported to, and/or maintained in, a specific location.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle localization","termid":"GO:0051640"}],"gene_count":25,"genes_by_uniquename":{"SJAG_00178":null,"SJAG_00471":null,"SJAG_00753":null,"SJAG_01013":null,"SJAG_01065":null,"SJAG_01338":null,"SJAG_01339":null,"SJAG_01358":null,"SJAG_01391":null,"SJAG_01449":null,"SJAG_02210":null,"SJAG_02250":null,"SJAG_02274":null,"SJAG_02757":null,"SJAG_03012":null,"SJAG_03299":null,"SJAG_03593":null,"SJAG_03719":null,"SJAG_03729":null,"SJAG_03882":null,"SJAG_04148":null,"SJAG_04308":null,"SJAG_04379":null,"SJAG_04721":null,"SJAG_04940":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"ribosome localization","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0033753"],"synonyms":[{"name":"establishment of ribosome localisation","type":"related"},{"name":"establishment of ribosome localization","type":"related"},{"name":"ribosome localisation","type":"related"}],"termid":"GO:0033750","terms_by_termid":{"GO:0000054":null,"GO:0000055":null,"GO:0000056":null}}


id: MONDO:0000259
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"dengue disease","termid":"MONDO:0005502"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"asymptomatic dengue","secondary_identifiers":["DOID:0050143"],"termid":"MONDO:0000259","xrefs":{"Monarch":{"xref_id":"0000259"}}}


id: PBO:0049430
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GUSB pseudogene 7","termid":"PBO:0049430"}


id: PBO:0089561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metaxin 1 (Sam37)","termid":"PBO:0089561"}


id: GO:0097646
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A G protein-coupled receptor signaling pathway initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.","definition_xrefs":["PMID:12037140","GOC:bhm","PMID:18687416","PMID:10871296"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor signaling pathway","termid":"GO:0007186"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"calcitonin family receptor signaling pathway","synonyms":[{"name":"calcitonin family receptor signalling pathway","type":"exact"}],"termid":"GO:0097646"}


id: MONDO:0021322
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cancer that involves the meningeal cluster.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system cancer","termid":"MONDO:0002714"},{"relation_name":"is_a","term_name":"tumor of meninges","termid":"MONDO:0016743"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"malignant tumor of meninges","secondary_identifiers":["MEDGEN:87594","NCIT:C4628","UMLS:C0348375","SCTID:363497007"],"synonyms":[{"name":"cancer of meningeal cluster","type":"exact"},{"name":"cancer of meninges","type":"exact"},{"name":"cancer of the meninges","type":"exact"},{"name":"malignant meningeal cluster neoplasm","type":"exact"},{"name":"malignant meningeal neoplasms","type":"exact"},{"name":"malignant meningeal tumor","type":"exact"},{"name":"malignant meningeal tumour","type":"exact"},{"name":"malignant meninges neoplasm","type":"exact"},{"name":"malignant meninges tumor","type":"exact"},{"name":"malignant meninges tumour","type":"exact"},{"name":"malignant neoplasm of meningeal cluster","type":"exact"},{"name":"malignant neoplasm of meninges","type":"exact"},{"name":"malignant neoplasm of the meninges","type":"exact"},{"name":"malignant neoplasms of meninges","type":"exact"},{"name":"malignant tumor of the meninges","type":"exact"},{"name":"malignant tumour of the meninges","type":"exact"},{"name":"meningeal cancer","type":"exact"},{"name":"meningeal cluster cancer","type":"exact"},{"name":"meningeal tumors, malignant","type":"exact"}],"termid":"MONDO:0021322","xrefs":{"Monarch":{"xref_id":"0021322"}}}


id: PBO:0077137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TIRAP antisense RNA 1","termid":"PBO:0077137"}


id: GO:0097222
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.","definition_xrefs":["GOC:ans","PMID:18083837"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial RNA processing","termid":"GO:0000963"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0140053"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0140053","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"mitochondrial mRNA polyadenylation","termid":"GO:0097222"}


id: PBO:0075766
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/arginine repetitive matrix 5","termid":"PBO:0075766"}


id: PBO:0043921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliary rootlet coiled-coil, rootletin family member 2","termid":"PBO:0043921"}


id: MOD:00762
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod N-linked glycosylation - missing ref","definition_xrefs":["Unimod:309"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N4-glycosyl-L-asparagine","termid":"MOD:00160"},{"relation_name":"is_a","term_name":"complex glycosylation","termid":"MOD:00725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"biantennary (-2 galactose) N4-glycosylated asparagine","synonyms":[{"name":"Biantennary (-2 galactose)","type":"related"},{"name":"Hex(3)HexNAc(4)","type":"related"}],"termid":"MOD:00762"}


id: PBO:0049653
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H4 clustered histone 7","termid":"PBO:0049653"}


id: PBO:0076847
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tescalcin","termid":"PBO:0076847"}


id: GO:0071388
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to cortisone","termid":"GO:0051413"},{"relation_name":"is_a","term_name":"cellular response to glucocorticoid stimulus","termid":"GO:0071385"},{"relation_name":"is_a","term_name":"cellular response to alcohol","termid":"GO:0097306"},{"relation_name":"is_a","term_name":"cellular response to ketone","termid":"GO:1901655"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to cortisone stimulus","termid":"GO:0071388"}


id: PBO:0069722
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1003, pseudogene","termid":"PBO:0069722"}


id: FYPO:0008175
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of oxygen consumed by cells in a given time is normal.","direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative phenotype","termid":"FYPO:0001312"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000257"],"is_obsolete":false,"name":"normal oxygen consumption","termid":"FYPO:0008175"}


id: PBO:0042830
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centrin 3","termid":"PBO:0042830"}


id: PBO:0051614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interleukin 36 receptor antagonist","termid":"PBO:0051614"}


id: PBO:0077070
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Thy-1 cell surface antigen","termid":"PBO:0077070"}


id: GO:0035111
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.","definition_xrefs":["PMID:12051824","GOC:bf","ISBN:0582227089"],"gene_count":0,"genotype_count":0,"name":"obsolete leg joint morphogenesis (obsolete GO:0035111)","synonyms":[{"name":"leg joint morphogenesis","type":"exact"}],"termid":"GO:0035111"}


id: PBO:0083297
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene VMA4/YOR332W","termid":"PBO:0083297"}


id: MONDO:0030057
data:
  {"annotated_genes":["SJAG_01022"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84877],"is_not":false,"summary":null,"term":"MONDO:0030057"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01022":null},"genotype_count":0,"is_obsolete":false,"name":"neurodevelopmental, jaw, eye, and digital syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:18523","MEDGEN:1712714","OMIM:618914","UMLS:C5394477"],"synonyms":[{"name":"NEDJED","type":"exact"},{"name":"NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME","type":"exact"},{"name":"neurodevelopmental, jaw, eye, and digital syndrome","type":"exact"}],"termid":"MONDO:0030057","terms_by_termid":{"MONDO:0030057":null},"xrefs":{"Monarch":{"xref_id":"0030057"}}}


id: PBO:0044063
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cystatin 9","termid":"PBO:0044063"}


id: MONDO:1012182
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial myopathy, non-human animal","termid":"MONDO:1011791"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial myopathy, dog","secondary_identifiers":["OMIA:000695-9615"],"termid":"MONDO:1012182","xrefs":{"Monarch":{"xref_id":"1012182"}}}


id: PBO:0079071
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Trp (anticodon CCA) 5-1","termid":"PBO:0079071"}


id: MONDO:0020032
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Rare urinary system benign neoplasm.","gene_count":0,"genotype_count":0,"name":"obsolete rare urinary tract tumor (obsolete MONDO:0020032)","secondary_identifiers":["Orphanet:98058"],"synonyms":[{"name":"rare urinary system neoplasm","type":"exact"},{"name":"rare urinary tract cancer","type":"exact"},{"name":"rare urinary tract neoplasm","type":"exact"}],"termid":"MONDO:0020032","xrefs":{"Monarch":{"xref_id":"0020032"}}}


id: FYPO:0002359
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in telomeric regions is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H3-K9 methylation during vegetative growth","termid":"FYPO:0003232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000257","FYPO:0001312","FYPO:0000002"],"is_obsolete":false,"name":"normal histone H3-K9 dimethylation at telomere during vegetative growth","synonyms":[{"name":"normal histone H3-K9 dimethylation at telomere during mitotic cell cycle","type":"related"},{"name":"normal histone H3K9me2 at telomere during vegetative growth","type":"exact"},{"name":"normal telomeric histone H3-K9 dimethylation during vegetative growth","type":"exact"}],"termid":"FYPO:0002359"}


id: GO:0010971
data:
  {"annotated_genes":["SJAG_04597","SJAG_04486","SJAG_02592","SJAG_03602","SJAG_03309","SJAG_00256","SJAG_00216","SJAG_04140","SJAG_01456","SJAG_01837","SJAG_02342","SJAG_01805","SJAG_00214","SJAG_04332","SJAG_00117","SJAG_03067","SJAG_00883","SJAG_03592","SJAG_01901","SJAG_03486","SJAG_01000"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[87563,87572,91242,91646,93303,93877,93916,94047,95829,97935,98501,101248,102977,106704,108034,109799,110653,115931,116117],"is_not":false,"summary":null,"term":"GO:0010971"},{"annotations":[87364,100875],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905287"}]},"cv_name":"biological_process","definition":"Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of G2/M transition of mitotic cell cycle","termid":"GO:0010389"},{"relation_name":"is_a","term_name":"positive regulation of mitotic cell cycle phase transition","termid":"GO:1901992"},{"relation_name":"is_a","term_name":"positive regulation of cell cycle G2/M phase transition","termid":"GO:1902751"},{"relation_name":"positively_regulates","term_name":"G2/M transition of mitotic cell cycle","termid":"GO:0000086"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00117":null,"SJAG_00214":null,"SJAG_00216":null,"SJAG_00256":null,"SJAG_00883":null,"SJAG_01000":null,"SJAG_01456":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_01901":null,"SJAG_02342":null,"SJAG_02592":null,"SJAG_03067":null,"SJAG_03309":null,"SJAG_03486":null,"SJAG_03592":null,"SJAG_03602":null,"SJAG_04140":null,"SJAG_04332":null,"SJAG_04486":null,"SJAG_04597":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044772"},{"rel_name":"positively_regulates","termid":"GO:0044772"},{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044772","GO:0008150","GO:0007049"],"is_obsolete":false,"name":"positive regulation of G2/M transition of mitotic cell cycle","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0031662"],"synonyms":[{"name":"positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle","type":"related"},{"name":"positive regulation of mitotic entry","type":"exact"}],"termid":"GO:0010971","terms_by_termid":{"GO:0010971":null,"GO:1905287":null}}


id: GO:0032953
data:
  {"annotated_genes":["SJAG_04666","SJAG_00610","SJAG_04771","SJAG_01255","SJAG_04659","SJAG_01787","SJAG_03705","SJAG_04462","SJAG_04668"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[91925],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0060635"},{"annotations":[91929,87036],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140748"},{"annotations":[102333,104814,91913,105384,117471,90283,91931,117347],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090334"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of beta-glucan biosynthetic process","termid":"GO:0032951"},{"relation_name":"is_a","term_name":"regulation of (1->3)-beta-D-glucan metabolic process","termid":"GO:0032952"},{"relation_name":"regulates","term_name":"(1->3)-beta-D-glucan biosynthetic process","termid":"GO:0006075"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00610":null,"SJAG_01255":null,"SJAG_01787":null,"SJAG_03705":null,"SJAG_04462":null,"SJAG_04659":null,"SJAG_04666":null,"SJAG_04668":null,"SJAG_04771":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"regulation of (1->3)-beta-D-glucan biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of 1,3-beta-glucan anabolism","type":"exact"},{"name":"regulation of 1,3-beta-glucan biosynthesis","type":"exact"},{"name":"regulation of 1,3-beta-glucan biosynthetic process","type":"broad"},{"name":"regulation of 1,3-beta-glucan formation","type":"exact"},{"name":"regulation of 1,3-beta-glucan synthesis","type":"exact"}],"termid":"GO:0032953","terms_by_termid":{"GO:0060635":null,"GO:0090334":null,"GO:0140748":null}}


id: FYPO:0006224
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferrous iron ions into a cell occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal ferrous iron import","termid":"FYPO:0006223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased ferrous iron import","synonyms":[{"name":"decreased cellular ferrous iron import","type":"exact"},{"name":"decreased ferrous ion import","type":"exact"},{"name":"decreased ferrous ion import across plasma membrane","type":"exact"},{"name":"decreased ferrous iron import during mitotic cell cycle","type":"related"},{"name":"decreased ferrous iron import during vegetative growth","type":"exact"},{"name":"decreased ferrous iron import into cell","type":"narrow"},{"name":"decreased ferrous iron ion import","type":"exact"},{"name":"reduced ferrous iron import","type":"exact"}],"termid":"FYPO:0006224"}


id: GO:0098977
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Synaptic transmission that results in an inhibitory postsynaptic potential.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemical synaptic transmission","termid":"GO:0007268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"inhibitory chemical synaptic transmission","termid":"GO:0098977"}


id: GO:2001019
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of intracellular transport","termid":"GO:0032388"},{"relation_name":"is_a","term_name":"regulation of retrograde axon cargo transport","termid":"GO:2001017"},{"relation_name":"positively_regulates","term_name":"retrograde axonal transport","termid":"GO:0008090"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of retrograde axon cargo transport","synonyms":[{"name":"positive regulation of retrograde axonal transport","type":"exact"}],"termid":"GO:2001019"}


id: PBO:0071088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 90","termid":"PBO:0071088"}


id: FYPO:0003619
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA splicing","termid":"FYPO:0003468"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000294","FYPO:0001320","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal mRNA splicing, via spliceosome","synonyms":[{"name":"normal mRNA splicing, via spliceosome during mitotic cell cycle","type":"related"},{"name":"normal mRNA splicing, via spliceosome during vegetative growth","type":"exact"},{"name":"normal nuclear mRNA splicing, via spliceosome","type":"exact"}],"termid":"FYPO:0003619"}


id: GO:0043879
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA).","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transmembrane transporter activity","termid":"GO:0008028"},{"relation_name":"is_a","term_name":"alcohol transmembrane transporter activity","termid":"GO:0015665"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"glycolate transmembrane transporter activity","synonyms":[{"name":"glcA","type":"related"},{"name":"glycolate permease","type":"related"},{"name":"glycolic acid transmembrane transporter activity","type":"exact"},{"name":"hydroxyacetic acid transmembrane transporter activity","type":"exact"}],"termid":"GO:0043879"}


id: SO:0000941
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A recombinationally rearranged gene of the vertebrate immune system.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"recombinationally_rearranged_gene","termid":"SO:0000456"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"recombinationally_rearranged_vertebrate_immune_system_gene","synonyms":[{"name":"recombinationally rearranged vertebrate immune system gene","type":"exact"}],"termid":"SO:0000941"}


id: PBO:0030323
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_oleoyl-CoA_ligase_activity","termid":"PBO:0030323"}


id: MONDO:0011108
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Stüve-Wiedemann syndrome (obsolete MONDO:0011108)","termid":"MONDO:0011108","xrefs":{"Monarch":{"xref_id":"0011108"}}}


id: GO:0019096
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.","definition_xrefs":["ISBN:0879694238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pole plasm mitochondrial rRNA localization","termid":"GO:0019095"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"pole plasm mitochondrial lrRNA localization","secondary_identifiers":["GO:0048118"],"synonyms":[{"name":"establishment and maintenance of mitochondrial lrRNA localization in pole plasm","type":"exact"},{"name":"oocyte pole plasm mitochondrial lrRNA localization","type":"exact"},{"name":"pole plasm mitochondrial lrRNA localisation","type":"exact"}],"termid":"GO:0019096"}


id: PBO:0082706
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; forms a subcomplex with Mic10p and Mic27p whose assembly and stability requires cardiolipin","termid":"PBO:0082706"}


id: MONDO:0054728
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 24","secondary_identifiers":["DOID:0111929","UMLS:C4693751","OMIM:617959","MEDGEN:1646063"],"synonyms":[{"name":"SPGF24","type":"related"},{"name":"spermatogenic failure 24","type":"exact"}],"termid":"MONDO:0054728","xrefs":{"Monarch":{"xref_id":"0054728"}}}


id: PBO:0088504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U2 snRNP-associated protein Sap62","termid":"PBO:0088504"}


id: PBO:0038870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aarF domain containing kinase 1","termid":"PBO:0038870"}


id: MONDO:0016560
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ptosis-syndactyly-learning difficulties syndrome","secondary_identifiers":["Orphanet:238766"],"termid":"MONDO:0016560","xrefs":{"Monarch":{"xref_id":"0016560"}}}


id: PBO:0028793
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_centromeric_outer_repeat_transcript_level","termid":"PBO:0028793"}


id: MONDO:0957985
data:
  {"annotated_genes":["SJAG_01477"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85586],"is_not":false,"summary":null,"term":"MONDO:0957985"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01477":null},"genotype_count":0,"is_obsolete":false,"name":"neurodegeneration, childhood-onset, with cerebellar ataxia and cognitive decline","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1847831","OMIM:620636","UMLS:C5882726"],"termid":"MONDO:0957985","terms_by_termid":{"MONDO:0957985":null},"xrefs":{"Monarch":{"xref_id":"0957985"}}}


id: PBO:0039355
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amidohydrolase domain containing 1","termid":"PBO:0039355"}


id: GO:1900498
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol.","definition_xrefs":["GOC:TermGenie","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of amide metabolic process","termid":"GO:0034249"},{"relation_name":"is_a","term_name":"negative regulation of fatty acid metabolic process","termid":"GO:0045922"},{"relation_name":"is_a","term_name":"negative regulation of nucleobase-containing compound metabolic process","termid":"GO:0045934"},{"relation_name":"is_a","term_name":"negative regulation of phosphate metabolic process","termid":"GO:0045936"},{"relation_name":"is_a","term_name":"negative regulation of lipid catabolic process","termid":"GO:0050995"},{"relation_name":"is_a","term_name":"negative regulation of lipid biosynthetic process","termid":"GO:0051055"},{"relation_name":"is_a","term_name":"negative regulation of sulfur metabolic process","termid":"GO:0051175"},{"relation_name":"is_a","term_name":"regulation of butyryl-CoA catabolic process to butanol","termid":"GO:1900497"},{"relation_name":"is_a","term_name":"negative regulation of alcohol biosynthetic process","termid":"GO:1902931"},{"relation_name":"negatively_regulates","term_name":"butyryl-CoA catabolic process to butanol","termid":"GO:0044582"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0055086"},{"rel_name":"negatively_regulates","termid":"GO:0006629"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0044248"},{"rel_name":"negatively_regulates","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006790"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"negatively_regulates","termid":"GO:0006790"},{"rel_name":"negatively_regulates","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0044248","GO:0044281","GO:0055086","GO:0008150","GO:0006790","GO:0006629"],"is_obsolete":false,"name":"negative regulation of butyryl-CoA catabolic process to butanol","synonyms":[{"name":"down regulation of butyryl-CoA catabolic process to butanol","type":"exact"},{"name":"down regulation of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"down-regulation of butyryl-CoA catabolic process to butanol","type":"exact"},{"name":"down-regulation of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"downregulation of butyryl-CoA catabolic process to butanol","type":"exact"},{"name":"downregulation of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"inhibition of butyryl-CoA catabolic process to butanol","type":"narrow"},{"name":"inhibition of butyryl-CoA catabolism to butanol","type":"exact"},{"name":"negative regulation of butyryl-CoA catabolism to butanol","type":"exact"}],"termid":"GO:1900498"}


id: GO:0075318
data:
  {"annotated_genes":["SJAG_03501"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117666],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0075319"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of spore-bearing organ development","termid":"GO:0075260"},{"relation_name":"regulates","term_name":"ascus development","termid":"GO:0075317"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03501":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of ascus development","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0075318","terms_by_termid":{"GO:0075319":null}}


id: PBO:0061228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-POU domain containing octamer binding","termid":"PBO:0061228"}


id: GO:0002632
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of granuloma formation","termid":"GO:0002631"},{"relation_name":"is_a","term_name":"negative regulation of chronic inflammatory response","termid":"GO:0002677"},{"relation_name":"is_a","term_name":"negative regulation of immune effector process","termid":"GO:0002698"},{"relation_name":"negatively_regulates","term_name":"granuloma formation","termid":"GO:0002432"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of granuloma formation","synonyms":[{"name":"down regulation of granuloma formation","type":"exact"},{"name":"down-regulation of granuloma formation","type":"exact"},{"name":"downregulation of granuloma formation","type":"exact"},{"name":"inhibition of granuloma formation","type":"narrow"}],"termid":"GO:0002632"}


id: GO:0043838
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol.","definition_xrefs":["PMID:15795227"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, for other substituted phosphate groups","termid":"GO:0016780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016780"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0003674","GO:0016780"],"is_obsolete":false,"name":"phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity","synonyms":[{"name":"EptB","type":"related"},{"name":"phosphoethanolamine transferase","type":"broad"}],"termid":"GO:0043838"}


id: PBO:0089230
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"clustered mitochondria ortholog Clu1","termid":"PBO:0089230"}


id: PBO:0081065
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger CW-type and PWWP domain containing 2","termid":"PBO:0081065"}


id: PBO:0060785
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B11","termid":"PBO:0060785"}


id: PBO:0018025
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human CDK7","termid":"PBO:0018025"}


id: GO:0005815
data:
  {"annotated_genes":["SJAG_03708","SJAG_00794","SJAG_01760","SJAG_02761","SJAG_01538","SJAG_02169","SJAG_01785","SJAG_02736","SJAG_03342","SJAG_00807","SJAG_01082","SJAG_00800","SJAG_02724","SJAG_02266","SJAG_02795","SJAG_04280","SJAG_00856","SJAG_00472","SJAG_01563","SJAG_04980","SJAG_04143","SJAG_02232","SJAG_04931","SJAG_05978","SJAG_02286","SJAG_04884","SJAG_03376","SJAG_02058","SJAG_03892","SJAG_01613","SJAG_01188","SJAG_01401","SJAG_00724","SJAG_03259","SJAG_01620","SJAG_02550","SJAG_03216","SJAG_03508","SJAG_05205","SJAG_05309","SJAG_04558","SJAG_05290","SJAG_03501","SJAG_02186","SJAG_00405","SJAG_04468","SJAG_01790","SJAG_02616","SJAG_01242","SJAG_02104","SJAG_01799","SJAG_02368","SJAG_00142","SJAG_02246","SJAG_02624","SJAG_02514","SJAG_05196","SJAG_01745","SJAG_02248","SJAG_05185","SJAG_03525","SJAG_02045","SJAG_04455","SJAG_01215","SJAG_03936","SJAG_01232","SJAG_01662","SJAG_03699","SJAG_05260","SJAG_00526","SJAG_00104","SJAG_02098","SJAG_02431","SJAG_04140","SJAG_01224","SJAG_02542","SJAG_04943","SJAG_01483","SJAG_03891","SJAG_00918","SJAG_02561","SJAG_00719","SJAG_01050","SJAG_03540","SJAG_02609","SJAG_07018","SJAG_05207","SJAG_00910","SJAG_03062","SJAG_04597","SJAG_00333","SJAG_01777","SJAG_03843","SJAG_04653","SJAG_00646","SJAG_04595","SJAG_04745","SJAG_00317","SJAG_03351","SJAG_00229","SJAG_04498","SJAG_02886","SJAG_00356","SJAG_03073","SJAG_00666","SJAG_05264","SJAG_02921","SJAG_01297","SJAG_01386","SJAG_06270","SJAG_02737","SJAG_02332","SJAG_04609","SJAG_01546","SJAG_00907","SJAG_03264","SJAG_01464","SJAG_03810","SJAG_03544","SJAG_03026","SJAG_02556","SJAG_03602","SJAG_03092","SJAG_01775","SJAG_01756","SJAG_03695","SJAG_02444","SJAG_01371","SJAG_04010","SJAG_03612","SJAG_03835","SJAG_00773","SJAG_03915","SJAG_01370","SJAG_03491","SJAG_05315","SJAG_00082","SJAG_02923","SJAG_05266","SJAG_04457","SJAG_04461","SJAG_03615","SJAG_03592","SJAG_03116","SJAG_00140","SJAG_03287","SJAG_03681","SJAG_01146","SJAG_00982","SJAG_00430","SJAG_00100","SJAG_01330","SJAG_03048","SJAG_00113","SJAG_01422","SJAG_03200","SJAG_04239","SJAG_01805","SJAG_04551","SJAG_03052","SJAG_02529","SJAG_04841","SJAG_02336","SJAG_04901"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[98712,103809,116512],"is_not":false,"summary":null,"term":"GO:0005815"},{"annotations":[92340,99161],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1990334"},{"annotations":[97778,99346,96361],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061493"},{"annotations":[89154],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0005814"},{"annotations":[100471,101807,100910,105909,99570,112203,99860,110025,108296,116626,109057,116376],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000923"},{"annotations":[116627,110026,109058,100472,105910,99571,108297,97142],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000931"},{"annotations":[109059,108298,100473,110027],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0008275"},{"annotations":[109060,112281,114563,110028,116377,108299,112077],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061496"},{"annotations":[110029,100474,102293,110879,108300,109061],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061497"},{"annotations":[100475,108301,109062,101808,96211,116378,102294,112204],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031021"},{"annotations":[110853,116366,90499,96264,90796,99413,110880,100215,109063,87268,99320,93362,101837,114564,91800,99348,100334,96366,110674,94704,100335,93289,86916,97074,117571,112078,102297,90232,113368,113369,89270,104568,99321,107813,103610,94806,102402],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0035974"},{"annotations":[96367,117577,110949,96782,117012,92758,97300,105783,90689,93760,92959,109625,104049,97780,104503,88469,99349,115957,117659,92343,100433,114735,97931,88752,111915,93292,117604,95822,105822,99626,96213,89156,89254,90890,108482,110882,93376,103304,110030,114354,104950,90500,116714,100008,109364,109064,91801,113104,92029,97528,118869,116641,112446,110372,86917,92428,95970,108213,110641,114245,106966,111130,99163,90234,116381,103373,107709,114911,118190,113936,93235,95772,101629,89498,95878,118881,106309,106561,109634,95459,100760,107002,118090,89123,98122,101809,108198,93912,91236,110499,101840,114565,100024,116628,112206,90842,99866,114130,112079,115342,94271,116458,96267,104822,93732,103201,107794,99100,90490,90643,100476,102531,106095,109014,109970,115446,100087,93440,95139,95888,99572,105911,89637,114392,116151,96951,102298,93905,108304,91259,101108,112283,90843,118871,99691,104646,105849,116735],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044732"},{"annotations":[102299,100434,105850,90644,106608,109971,104823,101841,99350,110642],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071958"},{"annotations":[109066,95141,92344,101844,105851,110032,99165,109973,113938,102302,108306,104505,112285,107004,110648],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071957"},{"annotations":[114912,106562,116382,108307],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061499"},{"annotations":[87269,118686,109637,118691,90236,118709,101810,93379,118530],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005816"}]},"cv_name":"cellular_component","definition":"An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.","definition_xrefs":["ISBN:0815316194","PMID:17072892","GOC:vw","PMID:17245416","Wikipedia:Microtubule_organizing_center"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"microtubule cytoskeleton","termid":"GO:0015630"}],"gene_count":164,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_00100":null,"SJAG_00104":null,"SJAG_00113":null,"SJAG_00140":null,"SJAG_00142":null,"SJAG_00229":null,"SJAG_00317":null,"SJAG_00333":null,"SJAG_00356":null,"SJAG_00405":null,"SJAG_00430":null,"SJAG_00472":null,"SJAG_00526":null,"SJAG_00646":null,"SJAG_00666":null,"SJAG_00719":null,"SJAG_00724":null,"SJAG_00773":null,"SJAG_00794":null,"SJAG_00800":null,"SJAG_00807":null,"SJAG_00856":null,"SJAG_00907":null,"SJAG_00910":null,"SJAG_00918":null,"SJAG_00982":null,"SJAG_01050":null,"SJAG_01082":null,"SJAG_01146":null,"SJAG_01188":null,"SJAG_01215":null,"SJAG_01224":null,"SJAG_01232":null,"SJAG_01242":null,"SJAG_01297":null,"SJAG_01330":null,"SJAG_01370":null,"SJAG_01371":null,"SJAG_01386":null,"SJAG_01401":null,"SJAG_01422":null,"SJAG_01464":null,"SJAG_01483":null,"SJAG_01538":null,"SJAG_01546":null,"SJAG_01563":null,"SJAG_01613":null,"SJAG_01620":null,"SJAG_01662":null,"SJAG_01745":null,"SJAG_01756":null,"SJAG_01760":null,"SJAG_01775":null,"SJAG_01777":null,"SJAG_01785":null,"SJAG_01790":null,"SJAG_01799":null,"SJAG_01805":null,"SJAG_02045":null,"SJAG_02058":null,"SJAG_02098":null,"SJAG_02104":null,"SJAG_02169":null,"SJAG_02186":null,"SJAG_02232":null,"SJAG_02246":null,"SJAG_02248":null,"SJAG_02266":null,"SJAG_02286":null,"SJAG_02332":null,"SJAG_02336":null,"SJAG_02368":null,"SJAG_02431":null,"SJAG_02444":null,"SJAG_02514":null,"SJAG_02529":null,"SJAG_02542":null,"SJAG_02550":null,"SJAG_02556":null,"SJAG_02561":null,"SJAG_02609":null,"SJAG_02616":null,"SJAG_02624":null,"SJAG_02724":null,"SJAG_02736":null,"SJAG_02737":null,"SJAG_02761":null,"SJAG_02795":null,"SJAG_02886":null,"SJAG_02921":null,"SJAG_02923":null,"SJAG_03026":null,"SJAG_03048":null,"SJAG_03052":null,"SJAG_03062":null,"SJAG_03073":null,"SJAG_03092":null,"SJAG_03116":null,"SJAG_03200":null,"SJAG_03216":null,"SJAG_03259":null,"SJAG_03264":null,"SJAG_03287":null,"SJAG_03342":null,"SJAG_03351":null,"SJAG_03376":null,"SJAG_03491":null,"SJAG_03501":null,"SJAG_03508":null,"SJAG_03525":null,"SJAG_03540":null,"SJAG_03544":null,"SJAG_03592":null,"SJAG_03602":null,"SJAG_03612":null,"SJAG_03615":null,"SJAG_03681":null,"SJAG_03695":null,"SJAG_03699":null,"SJAG_03708":null,"SJAG_03810":null,"SJAG_03835":null,"SJAG_03843":null,"SJAG_03891":null,"SJAG_03892":null,"SJAG_03915":null,"SJAG_03936":null,"SJAG_04010":null,"SJAG_04140":null,"SJAG_04143":null,"SJAG_04239":null,"SJAG_04280":null,"SJAG_04455":null,"SJAG_04457":null,"SJAG_04461":null,"SJAG_04468":null,"SJAG_04498":null,"SJAG_04551":null,"SJAG_04558":null,"SJAG_04595":null,"SJAG_04597":null,"SJAG_04609":null,"SJAG_04653":null,"SJAG_04745":null,"SJAG_04841":null,"SJAG_04884":null,"SJAG_04901":null,"SJAG_04931":null,"SJAG_04943":null,"SJAG_04980":null,"SJAG_05185":null,"SJAG_05196":null,"SJAG_05205":null,"SJAG_05207":null,"SJAG_05260":null,"SJAG_05264":null,"SJAG_05266":null,"SJAG_05290":null,"SJAG_05309":null,"SJAG_05315":null,"SJAG_05978":null,"SJAG_06270":null,"SJAG_07018":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0015630"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0015630"],"is_obsolete":false,"name":"microtubule organizing center","references_by_uniquename":{"GO_REF:0000107":null,"PMID:21733045":null,"PMID:32109380":null,"PMID:32243490":null},"synonyms":[{"name":"MTOC","type":"exact"},{"name":"microtubule organising centre","type":"exact"}],"termid":"GO:0005815","terms_by_termid":{"GO:0000093":null,"GO:0000923":null,"GO:0000931":null,"GO:0005814":null,"GO:0005815":null,"GO:0005816":null,"GO:0008275":null,"GO:0031021":null,"GO:0035974":null,"GO:0044732":null,"GO:0061493":null,"GO:0061496":null,"GO:0061497":null,"GO:0061499":null,"GO:0071957":null,"GO:0071958":null,"GO:1990334":null}}


id: GO:0071945
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.","definition_xrefs":["GOC:jl","GOC:cilia","PMID:20371342"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of bacterial-type flagellum-dependent cell motility","termid":"GO:1902021"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed","synonyms":[{"name":"regulation of bacterial-type flagellar cell motility by regulation of motor speed","type":"related"},{"name":"regulation of bacterial-type flagellum cell motility by regulation of motor speed","type":"exact"},{"name":"regulation of flagellar cell motility by regulation of motor speed","type":"broad"}],"termid":"GO:0071945"}


id: SO:0002050
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A promoter that allows for continual transcription of gene.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"promoter","termid":"SO:0000167"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"constitutive_promoter","synonyms":[{"name":"constitutive promoter","type":"exact"}],"termid":"SO:0002050"}


id: PBO:0029535
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_normal_volume_spheroid_vegetative_cell","termid":"PBO:0029535"}


id: MONDO:0054865
data:
  {"annotated_genes":["SJAG_02384","SJAG_02848"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85058,85057],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013726"}]},"cv_name":"mondo","definition":"A rare mitochondrial disease characterized by a variable phenotype comprising delayed psychomotor development or neurodevelopmental regression, hypotonia, seizures, microcephaly, optic atrophy, pyramidal signs, and peripheral neuropathy, among others. Age of onset and disease severity are also variable with some cases taking a fatal course in early infancy. Serum lactate levels may be elevated. Reported brain imaging findings include abnormal signals in the basal ganglia, cerebral and/or cerebellar atrophy, and white matter abnormalities.","definition_xrefs":["Orphanet:527276"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brain disorder","termid":"MONDO:0005560"},{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"},{"relation_name":"is_a","term_name":"disorder of defective peroxisomal and mitochondrial fission","termid":"MONDO:0100276"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02384":null,"SJAG_02848":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0019053"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0019053","MONDO:0004069"],"is_obsolete":false,"name":"encephalopathy due to mitochondrial and peroxisomal fission defect","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1814479","OMIMPS:614388","UMLS:C5681458","GARD:22192"],"synonyms":[{"name":"encephalopathy due to defective mitochondrial and peroxisomal fission","type":"exact"},{"name":"encephalopathy due to mitochondrial and peroxisomal fission defect","type":"exact"}],"termid":"MONDO:0054865","terms_by_termid":{"MONDO:0013726":null},"xrefs":{"Monarch":{"xref_id":"0054865"}}}


id: GO:0030393
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic acid metabolic process","termid":"GO:0019752"},{"relation_name":"is_a","term_name":"fructosamine metabolic process","termid":"GO:0030389"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"fructoselysine metabolic process","synonyms":[{"name":"fructoselysine metabolism","type":"exact"}],"termid":"GO:0030393"}


id: FYPO:0005037
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation.","definition_xrefs":["GO:0071620","PMID:22144909","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein phosphorylation during nitrogen starvation","termid":"FYPO:0005035"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during nitrogen starvation","synonyms":[{"name":"decreased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during nitrogen deprivation","type":"exact"},{"name":"decreased phosphorylation of RNA polymerase II CTD serine 5 residues during nitrogen depletion","type":"exact"},{"name":"reduced phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during nitrogen starvation","type":"exact"}],"termid":"FYPO:0005037"}


id: MONDO:0018947
data:
  {"annotated_genes":["SJAG_00185","SJAG_03248"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85005],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009709"},{"annotations":[84983],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010683"}]},"cv_name":"mondo","definition":"Centronuclear myopathy (CNM) is an inherited neuromuscular disorder characterized by clinical features of a congenital myopathy and centrally placed nuclei on muscle biopsy.","definition_xrefs":["Orphanet:595"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete rare disorder with ptosis (obsolete MONDO:0020169)","termid":"MONDO:0020169"},{"relation_name":"is_a","term_name":"congenital myopathy","termid":"MONDO:0019952"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00185":null,"SJAG_03248":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"centronuclear myopathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:742097637","MESH:D020914","NANDO:2200867","NANDO:1200482","NCIT:C84648","OMIMPS:160150","GARD:101","DOID:14717","MEDGEN:104495","NANDO:1200481","NORD:909","UMLS:C0175709","SCTID:82077006"],"synonyms":[{"name":"CNM","type":"exact"},{"name":"centronuclear myopathy","type":"exact"},{"name":"myopathy, centronuclear","type":"exact"},{"name":"myopathy, myotubular","type":"related"},{"name":"myotubular myopathy","type":"exact"}],"termid":"MONDO:0018947","terms_by_termid":{"MONDO:0009709":null,"MONDO:0010683":null},"xrefs":{"Monarch":{"xref_id":"0018947"}}}


id: MONDO:0016041
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital microgastria is a rare malformation where the embryological development of the stomach is interrupted, leading to an abnormally small foregut in newborns and characterized by extreme feeding intolerance and malnutrition along with growth retardation and death if untreated. It is usually associated with multiple congenital anomalies.","definition_xrefs":["Orphanet:199293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital microgastria","secondary_identifiers":["icd11.foundation:1695007532","GARD:20330","SCTID:83714006","MEDGEN:82732","UMLS:C0266150","ICD9:750.7"],"termid":"MONDO:0016041","xrefs":{"Monarch":{"xref_id":"0016041"}}}


id: PBO:0074492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"snail family transcriptional repressor 3","termid":"PBO:0074492"}


id: MONDO:0010683
data:
  {"annotated_genes":["SJAG_03248"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84983],"is_not":false,"summary":null,"term":"MONDO:0010683"}]},"cv_name":"mondo","definition":"A rare X-linked congenital myopathy characterized by numerous centrally placed nuclei on muscle biopsy and that presents at birth with marked weakness, hypotonia and respiratory failure.","definition_xrefs":["Orphanet:596"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"congenital structural myopathy","termid":"MONDO:0002921"},{"relation_name":"excluded_subClassOf","term_name":"obsolete qualitative or quantitative defects of myotubularin (obsolete MONDO:0016154)","termid":"MONDO:0016154"},{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"},{"relation_name":"is_a","term_name":"centronuclear myopathy","termid":"MONDO:0018947"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03248":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"X-linked myotubular myopathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:11925","MEDGEN:98374","NCIT:C118781","OMIM:310400","SCTID:46804001","UMLS:C0410203","DOID:0111225"],"synonyms":[{"name":"CNMX","type":"related"},{"name":"MTM","type":"exact"},{"name":"X-linked centronuclear myopathy","type":"exact"},{"name":"X-linked myotubular myopathy","type":"exact"},{"name":"XLCNM","type":"exact"},{"name":"XLMTM","type":"exact"},{"name":"centronuclear myopathy, X-linked","type":"exact"},{"name":"myopathy, centronuclear, X-linked","type":"related"},{"name":"myotubular myopathy 1","type":"related"},{"name":"myotubular myopathy, X-linked","type":"related"},{"name":"myotubular myopathy, X-linked, X-linked recessive","type":"exact"}],"termid":"MONDO:0010683","terms_by_termid":{"MONDO:0010683":null},"xrefs":{"Monarch":{"xref_id":"0010683"}}}


id: GO:0016882
data:
  {"annotated_genes":["SJAG_01616","SJAG_00673","SJAG_03140"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[104073],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030272"},{"annotations":[75770],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004141"},{"annotations":[109711],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004641"}]},"cv_name":"molecular_function","definition":"Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.","definition_xrefs":["GOC:mah","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ligase activity, forming carbon-nitrogen bonds","termid":"GO:0016879"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00673":null,"SJAG_01616":null,"SJAG_03140":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016874"],"is_obsolete":false,"name":"cyclo-ligase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["EC:6.3.3.-"],"termid":"GO:0016882","terms_by_termid":{"GO:0004141":null,"GO:0004641":null,"GO:0030272":null}}


id: PBO:0054440
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1837","termid":"PBO:0054440"}


id: MONDO:0006769
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"functional gastric disease","termid":"MONDO:0001318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"gastroparesis","secondary_identifiers":["MESH:D018589","SCTID:196753007","EFO:1000948","UMLS:C0152020","HP:0002578","ICD9:536.3","MedDRA:10018043","MEDGEN:101809","DOID:11914","icd11.foundation:598423727","ICD10CM:K31.84"],"synonyms":[{"name":"gastric atonia","type":"exact"},{"name":"gastroparalysis","type":"exact"},{"name":"gastroparesis","type":"exact"},{"name":"gastroparesis (disease)","type":"exact"},{"name":"gastroparesis syndrome","type":"exact"}],"termid":"MONDO:0006769","xrefs":{"Monarch":{"xref_id":"0006769"}}}


id: MONDO:0025303
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease or disorder caused by infection with Anaplasma.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Anaplasmataceae infectious disease","termid":"MONDO:0006922"},{"relation_name":"is_a","term_name":"tick-borne infectious disease","termid":"MONDO:0025294"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaplasmosis","secondary_identifiers":["SCTID:427481004","ICD9:082.49","MESH:D000712","NCIT:C128425","SCTID:13906002","MEDGEN:8053","UMLS:C0002797"],"synonyms":[{"name":"anaplasma caused disease or disorder","type":"exact"},{"name":"anaplasma disease or disorder","type":"exact"},{"name":"anaplasma infectious disease","type":"exact"},{"name":"anaplasmoses","type":"exact"},{"name":"human anaplasmosis","type":"exact"}],"termid":"MONDO:0025303","xrefs":{"Monarch":{"xref_id":"0025303"}}}


id: PBO:0029925
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_ionizing_radiation_during_vegetative_growth","termid":"PBO:0029925"}


id: FYPO:0007848
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during one or both meiotic nuclear divisions. This phenotype is observed in the absence of both bouquet formation and meiotic SPB insertion into the nuclear envelope.","definition_xrefs":["PomBase:mah","PMID:34346498"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiotic spindle assembly","termid":"FYPO:0000737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0005447","FYPO:0000054","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"meiotic spindle self-assembly","synonyms":[{"name":"SPB-independent meiotic spindle assembly","type":"exact"},{"name":"SPB-independent spindle assembly during meiosis","type":"exact"},{"name":"acentrosomal meiotic spindle assembly","type":"related"},{"name":"acentrosomal spindle assembly during meiosis","type":"related"},{"name":"meiotic SPB-independent spindle","type":"related"},{"name":"spindle pole body-independent meiotic spindle assembly","type":"exact"},{"name":"spindle pole body-independent spindle assembly during meiosis","type":"exact"},{"name":"spindle self-assembly during meiosis","type":"exact"},{"name":"spindle self-assembly during meiotic nuclear division","type":"exact"}],"termid":"FYPO:0007848"}


id: PATO:0000450
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000450 low percentage (obsolete PATO:0000450)","termid":"PATO:0000450"}


id: PBO:0067594
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 756, pseudogene","termid":"PBO:0067594"}


id: GO:1900199
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II.","definition_xrefs":["GOC:al","PMID:20970342","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein export from nucleus","termid":"GO:0046827"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006913"},{"rel_name":"positively_regulates","termid":"GO:0006913"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0006913"],"is_obsolete":false,"name":"positive regulation of protein export from nucleus during meiotic anaphase II","synonyms":[{"name":"positive regulation of protein export from nucleus involved in meiotic anaphase II","type":"broad"}],"termid":"GO:1900199"}


id: PR:O74863
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC18.13 gene.","definition_xrefs":["UniProtKB:O74863","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit trm82 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC18.13","synonyms":[{"name":"Spom972h-SPCC18.13","type":"exact"},{"name":"transfer RNA methyltransferase 82 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74863"}


id: GO:0097201
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).","definition_xrefs":["GOC:rn","PMID:15575969","PMID:16556235","PMID:18086556","PMID:11027285","PMID:18627600"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of transcription from RNA polymerase II promoter in response to stress (obsolete GO:0097201)","termid":"GO:0097201"}


id: GO:0102466
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete beta-carotene 2,2'-beta-hydroxylase activity (obsolete GO:0102466)","termid":"GO:0102466"}


id: PBO:0063015
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAGE family member 3","termid":"PBO:0063015"}


id: PBO:0045497
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DSG1 antisense RNA 1","termid":"PBO:0045497"}


id: PBO:0061287
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore associated protein 1 pseudogene 8","termid":"PBO:0061287"}


id: PBO:0028820
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_replication_fork_reversal","termid":"PBO:0028820"}


id: MONDO:0007662
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any iridogoniodysgenesis in which the cause of the disease is a mutation in the PITX2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Rieger anomaly","termid":"MONDO:0019628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"anterior segment dysgenesis 4","secondary_identifiers":["OMIM:137600","UMLS:C1842031","DOID:0080609","MEDGEN:330750","GARD:3026"],"synonyms":[{"name":"ASGD4","type":"related"},{"name":"IRID2","type":"exact"},{"name":"PITX2 iridogoniodysgenesis","type":"exact"},{"name":"anterior segment dysgenesis 4","type":"exact"},{"name":"iridogoniodysgenesis caused by mutation in PITX2","type":"exact"},{"name":"iridogoniodysgenesis syndrome","type":"broad"},{"name":"iridogoniodysgenesis type 2","type":"related"},{"name":"iridogoniodysgenesis, type 2","type":"exact"},{"name":"iris hypoplasia with early-onset glaucoma, autosomal dominant","type":"related"}],"termid":"MONDO:0007662","xrefs":{"Monarch":{"xref_id":"0007662"}}}


id: GO:0140237
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Translation that occurs at the presynapse, and that modulates chemical synaptic transmission.","definition_xrefs":["PMID:27321671"],"direct_ancestors":[{"relation_name":"is_a","term_name":"translation at presynapse","termid":"GO:0140236"},{"relation_name":"regulates","term_name":"chemical synaptic transmission","termid":"GO:0007268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0023052"],"is_obsolete":false,"name":"translation at presynapse, modulating chemical synaptic transmission","termid":"GO:0140237"}


id: SO:0000096
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene from proplastid sequence.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"has_origin","term_name":"proplastid_sequence","termid":"SO:0000748"},{"relation_name":"is_a","term_name":"plastid_gene","termid":"SO:0000090"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proplastid_gene","synonyms":[{"name":"proplastid gene","type":"exact"}],"termid":"SO:0000096"}


id: PR:O13959
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An E3 ubiquitin-protein ligase RBX1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00632","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RING-box protein pip1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC23H4.18c","secondary_identifiers":["UniProtKB:O13959"],"synonyms":[{"name":"Pop-interacting protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RING-box protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-RBX1","type":"exact"}],"termid":"PR:O13959"}


id: GO:0006968
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A defense response that is mediated by cells.","definition_xrefs":["GOC:ebc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"defense response","termid":"GO:0006952"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular defense response","secondary_identifiers":["GO:0002818","GO:0016067","GO:0016066"],"synonyms":[{"name":"cellular defence response","type":"exact"},{"name":"intracellular defence response","type":"narrow"},{"name":"intracellular defense response","type":"narrow"}],"termid":"GO:0006968"}


id: GO:0047912
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H+.","definition_xrefs":["EC:2.7.1.44","RHEA:12965"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016301","GO:0016740"],"is_obsolete":false,"name":"galacturonokinase activity","secondary_identifiers":["KEGG_REACTION:R01980","MetaCyc:GALACTURONOKINASE-RXN"],"synonyms":[{"name":"ATP:D-galacturonate 1-phosphotransferase activity","type":"related"},{"name":"galacturonokinase (phosphorylating) D-galacturonic acid kinase activity","type":"related"}],"termid":"GO:0047912"}


id: GO:0061974
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.","definition_xrefs":["PMID:21901110"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endochondral bone morphogenesis","termid":"GO:0060350"},{"relation_name":"is_a","term_name":"membrane bone morphogenesis","termid":"GO:0061973"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"perichondral bone morphogenesis","termid":"GO:0061974"}


id: PBO:0052609
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KRAB-A domain containing 2","termid":"PBO:0052609"}


id: PBO:0030425
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-constricted_nucleus","termid":"PBO:0030425"}


id: GO:0070008
data:
  {"annotated_genes":["SJAG_01868","SJAG_04819","SJAG_04928","SJAG_00975"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[87724,91330,103877],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004185"},{"annotations":[100787],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008240"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"serine-type peptidase activity","termid":"GO:0008236"},{"relation_name":"is_a","term_name":"exopeptidase activity","termid":"GO:0008238"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00975":null,"SJAG_01868":null,"SJAG_04819":null,"SJAG_04928":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0008233"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824","GO:0008233","GO:0140096"],"is_obsolete":false,"name":"serine-type exopeptidase activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0070008","terms_by_termid":{"GO:0004185":null,"GO:0008240":null}}


id: PBO:0075263
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 18 pseudogene 16","termid":"PBO:0075263"}


id: MONDO:1012896
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hearing loss that occurs in pigs due to a mutation in the GJB2 gene created by genetic engineering or gene editing.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss disorder, non-human animal","termid":"MONDO:1012969"},{"relation_name":"is_a","term_name":"inherited auditory system disease, non-human animal","termid":"MONDO:1012970"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deafness, GJB2-related, pig","secondary_identifiers":["OMIA:002439-9823"],"termid":"MONDO:1012896","xrefs":{"Monarch":{"xref_id":"1012896"}}}


id: GO:0000144
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.","definition_xrefs":["GOC:krc","PMID:16009555"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular bud neck septin structure","termid":"GO:0000399"},{"relation_name":"is_a","term_name":"septin ring","termid":"GO:0005940"},{"relation_name":"is_a","term_name":"cleavage apparatus septin structure","termid":"GO:0032161"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005938"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005938","GO:0005575"],"is_obsolete":false,"name":"cellular bud neck septin ring","termid":"GO:0000144"}


id: PBO:0075182
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear ribonucleoprotein polypeptide F","termid":"PBO:0075182"}


id: MONDO:0003900
data:
  {"annotated_genes":["SJAG_04118","SJAG_05213","SJAG_02855","SJAG_03453","SJAG_01474","SJAG_03905","SJAG_04541","SJAG_03429","SJAG_05239","SJAG_01344","SJAG_02039","SJAG_04290","SJAG_01884","SJAG_03805","SJAG_04077","SJAG_00400","SJAG_03151","SJAG_01748","SJAG_03785","SJAG_01013","SJAG_00031","SJAG_00321","SJAG_03881","SJAG_04287","SJAG_01349","SJAG_04969","SJAG_00853","SJAG_04380","SJAG_04569","SJAG_02763","SJAG_04865","SJAG_03596","SJAG_01151","SJAG_05979"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86889,86736,86733,86735,86734,86888],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0018874"},{"annotations":[84874],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012429"},{"annotations":[84704],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012471"},{"annotations":[84707],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012472"},{"annotations":[84793],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014007"},{"annotations":[86802],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014629"},{"annotations":[86757],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013944"},{"annotations":[84699,84700,84701],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009925"},{"annotations":[85694],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0002629"},{"annotations":[84861],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010621"},{"annotations":[86259],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009050"},{"annotations":[86318],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007205"},{"annotations":[85556],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007483"},{"annotations":[86175],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013766"},{"annotations":[86279,86278],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009849"},{"annotations":[85196],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007767"},{"annotations":[85197],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007768"},{"annotations":[85421],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012316"},{"annotations":[84602,84601],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012481"},{"annotations":[86214],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007908"},{"annotations":[86274],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054698"},{"annotations":[86085],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054700"},{"annotations":[84958,84957],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054699"},{"annotations":[84656,84657],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011462"},{"annotations":[85959],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024541"},{"annotations":[85810],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013818"},{"annotations":[85427],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0026777"},{"annotations":[85176],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010523"}]},"cv_name":"mondo","definition":"A disease involving the connective tissue.","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"musculoskeletal system disorder","termid":"MONDO:0002081"},{"relation_name":"is_a","term_name":"human disease","termid":"MONDO:0700096"}],"gene_count":34,"genes_by_uniquename":{"SJAG_00031":null,"SJAG_00321":null,"SJAG_00400":null,"SJAG_00853":null,"SJAG_01013":null,"SJAG_01151":null,"SJAG_01344":null,"SJAG_01349":null,"SJAG_01474":null,"SJAG_01748":null,"SJAG_01884":null,"SJAG_02039":null,"SJAG_02763":null,"SJAG_02855":null,"SJAG_03151":null,"SJAG_03429":null,"SJAG_03453":null,"SJAG_03596":null,"SJAG_03785":null,"SJAG_03805":null,"SJAG_03881":null,"SJAG_03905":null,"SJAG_04077":null,"SJAG_04118":null,"SJAG_04287":null,"SJAG_04290":null,"SJAG_04380":null,"SJAG_04541":null,"SJAG_04569":null,"SJAG_04865":null,"SJAG_04969":null,"SJAG_05213":null,"SJAG_05239":null,"SJAG_05979":null},"genotype_count":0,"is_obsolete":false,"name":"connective tissue disorder","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C26729","UMLS:C0009782","EFO:1001986","MESH:D003240","NANDO:2100172","MEDGEN:1098","SCTID:105969002","DOID:65"],"synonyms":[{"name":"connective tissue disease","type":"exact"},{"name":"connective tissue disease or disorder","type":"exact"},{"name":"connective tissue diseases","type":"exact"},{"name":"connective tissue disorder","type":"exact"},{"name":"connective tissue disorders","type":"exact"},{"name":"disease of connective tissue","type":"exact"},{"name":"disease or disorder of connective tissue","type":"exact"},{"name":"disease, connective tissue","type":"exact"},{"name":"disorder of connective tissue","type":"exact"},{"name":"primary disorder of connective tissue","type":"exact"},{"name":"tissue disease, connective","type":"exact"}],"termid":"MONDO:0003900","terms_by_termid":{"MONDO:0002629":null,"MONDO:0007205":null,"MONDO:0007483":null,"MONDO:0007767":null,"MONDO:0007768":null,"MONDO:0007908":null,"MONDO:0009050":null,"MONDO:0009849":null,"MONDO:0009925":null,"MONDO:0010523":null,"MONDO:0010621":null,"MONDO:0011462":null,"MONDO:0012316":null,"MONDO:0012429":null,"MONDO:0012471":null,"MONDO:0012472":null,"MONDO:0012481":null,"MONDO:0013766":null,"MONDO:0013818":null,"MONDO:0013944":null,"MONDO:0014007":null,"MONDO:0014629":null,"MONDO:0018874":null,"MONDO:0024541":null,"MONDO:0026777":null,"MONDO:0054698":null,"MONDO:0054699":null,"MONDO:0054700":null},"xrefs":{"Monarch":{"xref_id":"0003900"}}}


id: GO:1902966
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.","definition_xrefs":["GO_REF:0000058","GOC:sjp","GOC:TermGenie","PMID:22621900"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein localization to early endosome","termid":"GO:1902965"},{"relation_name":"is_a","term_name":"positive regulation of protein localization to endosome","termid":"GO:1905668"},{"relation_name":"positively_regulates","term_name":"protein localization to early endosome","termid":"GO:1902946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein localization to early endosome","synonyms":[{"name":"activation of protein localisation in early endosome","type":"narrow"},{"name":"activation of protein localisation to early endosome","type":"narrow"},{"name":"activation of protein localization in early endosome","type":"narrow"},{"name":"activation of protein localization to early endosome","type":"narrow"},{"name":"positive regulation of protein localisation in early endosome","type":"exact"},{"name":"positive regulation of protein localisation to early endosome","type":"exact"},{"name":"positive regulation of protein localization in early endosome","type":"exact"},{"name":"up regulation of protein localisation in early endosome","type":"exact"},{"name":"up regulation of protein localisation to early endosome","type":"exact"},{"name":"up regulation of protein localization in early endosome","type":"exact"},{"name":"up regulation of protein localization to early endosome","type":"exact"},{"name":"up-regulation of protein localisation in early endosome","type":"exact"},{"name":"up-regulation of protein localisation to early endosome","type":"exact"},{"name":"up-regulation of protein localization in early endosome","type":"exact"},{"name":"up-regulation of protein localization to early endosome","type":"exact"},{"name":"upregulation of protein localisation in early endosome","type":"exact"},{"name":"upregulation of protein localisation to early endosome","type":"exact"},{"name":"upregulation of protein localization in early endosome","type":"exact"},{"name":"upregulation of protein localization to early endosome","type":"exact"}],"termid":"GO:1902966"}


id: PBO:0061182
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear-encoded mitochondrial tRNA-Gln (TTG) 12-1","termid":"PBO:0061182"}


id: GO:1901009
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of (S)-scoulerine.","definition_xrefs":["PMID:15672841","GOC:yaf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoquinoline alkaloid biosynthetic process","termid":"GO:0033075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"(S)-scoulerine biosynthetic process","synonyms":[{"name":"(S)-scoulerine anabolism","type":"exact"},{"name":"(S)-scoulerine biosynthesis","type":"exact"},{"name":"(S)-scoulerine formation","type":"exact"},{"name":"(S)-scoulerine synthesis","type":"exact"}],"termid":"GO:1901009"}


id: GO:0003106
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the process whereby blood is filtered by the glomerulus into the renal tubule.","definition_xrefs":["GOC:mah","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of renal output by angiotensin","termid":"GO:0003083"},{"relation_name":"part_of","term_name":"negative regulation of glomerular filtration","termid":"GO:0003105"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of glomerular filtration by angiotensin","synonyms":[{"name":"angiotensin-mediated regulation of glomerular filtration","type":"broad"},{"name":"regulation of glomerular filtration by angiotensin","type":"broad"}],"termid":"GO:0003106"}


id: GO:0099037
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the presynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.","definition_xrefs":["GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete anchored component of presynaptic endosome membrane (obsolete GO:0099037)","termid":"GO:0099037"}


id: GO:0060755
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of leukocyte chemotaxis","termid":"GO:0002689"},{"relation_name":"is_a","term_name":"regulation of mast cell chemotaxis","termid":"GO:0060753"},{"relation_name":"negatively_regulates","term_name":"mast cell chemotaxis","termid":"GO:0002551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of mast cell chemotaxis","termid":"GO:0060755"}


id: PR:O94612
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A cyclin-related protein FAM58A that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized cyclin-L1-like protein C1296.05c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1296.05c","secondary_identifiers":["UniProtKB:O94612"],"synonyms":[{"name":"Spom972h-FAM58A","type":"exact"}],"termid":"PR:O94612"}


id: PBO:0064602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POU class 2 homeobox 3","termid":"PBO:0064602"}


id: PBO:0083485
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene VHS3/YOR054C","termid":"PBO:0083485"}


id: FYECO:0000155
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which choline was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ choline","termid":"FYECO:0000155"}


id: GO:0018689
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete naphthalene disulfonate 1,2-dioxygenase activity (obsolete GO:0018689)","synonyms":[{"name":"naphthalene disulphonate 1,2-dioxygenase activity","type":"exact"}],"termid":"GO:0018689"}


id: PBO:0036097
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_histone_H3-K9_trimethylation_at_subtelomere_during_vegetative_growth","termid":"PBO:0036097"}


id: GO:0099052
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane.","definition_xrefs":["PMID:21779028"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle scission involved in endocytosis","termid":"GO:0099051"},{"relation_name":"part_of","term_name":"clathrin-dependent endocytosis","termid":"GO:0072583"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0061024","GO:0006810","GO:0016192","GO:0008150"],"is_obsolete":false,"name":"vesicle scission involved in clathrin-mediated endocytosis","termid":"GO:0099052"}


id: GO:0071516
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.","definition_xrefs":["PMID:18723894","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete establishment of imprinting at mating-type locus (obsolete GO:0071516)","synonyms":[{"name":"mating type determination, establishment of imprinting","type":"exact"}],"termid":"GO:0071516"}


id: PBO:0064595
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POU class 2 homeobox associating factor 1","termid":"PBO:0064595"}


id: PBO:0042913
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CASP8 and FADD like apoptosis regulator","termid":"PBO:0042913"}


id: PBO:0035719
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_ubiquitination_during_vegetative_growth","termid":"PBO:0035719"}


id: GO:0140729
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme.","definition_xrefs":["PMID:21923907","PMID:29763292"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detoxification","termid":"GO:0098754"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098754"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0098754","GO:0008150"],"is_obsolete":false,"name":"self-resistance to endogenously produced metabolite","synonyms":[{"name":"prevention of self-toxicity","type":"exact"},{"name":"self-resistance to bioactive secondary metabolite","type":"exact"},{"name":"self-resistance to endogenously produced compound","type":"exact"},{"name":"self-resistance to endogenously produced toxin","type":"exact"}],"termid":"GO:0140729"}


id: PBO:0071242
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 83","termid":"PBO:0071242"}


id: GO:1903115
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of actin filament-based movement.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:24798735"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of actin filament-based process","termid":"GO:0032970"},{"relation_name":"regulates","term_name":"actin filament-based movement","termid":"GO:0030048"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of actin filament-based movement","termid":"GO:1903115"}


id: PBO:0077119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translocase of inner mitochondrial membrane 50","termid":"PBO:0077119"}


id: FYPO_EXT:0000004
data:
  {"annotation_feature_type":"gene","cv_name":"fypo_extensions","definition":"all cells (penetrance)","definition_xrefs":["PomBase:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"FYPO penetrance extension","termid":"FYPO_EXT:1000002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complete","synonyms":[{"name":"100%","type":"exact"},{"name":"full","type":"exact"}],"termid":"FYPO_EXT:0000004"}


id: PBO:0088634
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial hydrolase","termid":"PBO:0088634"}


id: PBO:0090644
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TIM23 translocase complex subunit Tim15","termid":"PBO:0090644"}


id: GO:0160138
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: uridine(2604) in 23S rRNA = pseudouridine(2604) in 23S rRNA.","definition_xrefs":["RHEA:38875","EC:5.4.99.21"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA pseudouridine synthase activity","termid":"GO:0120159"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"}],"interesting_parent_ids":["GO:0016853","GO:0140098","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"23S rRNA pseudouridine(2604) synthase activity","termid":"GO:0160138"}


id: MONDO:0020333
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Aggressive systemic mastocytosis (ASM) is a severe and rare form of systemic mastocytosis (SM) characterized by considerable infiltration of mast cells in different tissues.","definition_xrefs":["Orphanet:98850"],"direct_ancestors":[{"relation_name":"is_a","term_name":"systemic mastocytosis","termid":"MONDO:0016586"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"aggressive systemic mastocytosis","secondary_identifiers":["NCIT:C9285","GARD:19597","ICDO:9741/3","DOID:4798","icd11.foundation:870477963","ONCOTREE:ASM","MEDGEN:206813","UMLS:C1112486","SCTID:716655008","MedDRA:10056453"],"synonyms":[{"name":"ASM","type":"exact"},{"name":"aggressive systemic mastocytosis (morphologic abnormality)","type":"exact"},{"name":"lymphadenopathic mastocytosis with eosinophilia","type":"exact"}],"termid":"MONDO:0020333","xrefs":{"Monarch":{"xref_id":"0020333"}}}


id: GO:0003301
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.","definition_xrefs":["GOC:BHF","GOC:mtg_cardiac_conduct_nov11","GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"physiological muscle hypertrophy","termid":"GO:0003298"},{"relation_name":"is_a","term_name":"cardiac muscle hypertrophy","termid":"GO:0003300"},{"relation_name":"part_of","term_name":"cardiac muscle tissue growth","termid":"GO:0055017"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"physiological cardiac muscle hypertrophy","termid":"GO:0003301"}


id: PBO:0000440
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit Pmc2/Med1","termid":"PBO:0000440"}


id: PBO:0047646
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FKBP prolyl isomerase 3","termid":"PBO:0047646"}


id: PBO:0056059
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich adaptor protein 1 like","termid":"PBO:0056059"}


id: FYPO:0004300
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of an ATPase activity is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal catalytic activity","termid":"FYPO:0000660"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000652","FYPO:0000654"],"is_obsolete":false,"name":"normal ATPase activity","termid":"FYPO:0004300"}


id: MONDO:0012108
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A spondyloepimetaphyseal dysplasia characterized by disproportionate early-onset dwarfism, bowing of the lower limbs, short, wide and stocky long bones with severe epiphyseal and metaphyseal changes, lumbar lordosis, hypoplastic iliac bones, flat ovoid vertebral bodies and normal hands.","definition_xrefs":["Orphanet:156728"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"spondyloepiphyseal dysplasia","termid":"MONDO:0016761"},{"relation_name":"is_a","term_name":"spondyloepimetaphyseal dysplasia","termid":"MONDO:0100510"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"spondyloepimetaphyseal dysplasia, matrilin-3 type","secondary_identifiers":["UMLS:C1837481","MESH:C563869","icd11.foundation:1983063881","MEDGEN:325181","GARD:10611","OMIM:608728","SCTID:719166003"],"synonyms":[{"name":"SEMD MATN3-related","type":"related"},{"name":"SEMD, MATN3-related","type":"exact"},{"name":"SEMD, matrilin-3 type","type":"exact"},{"name":"spondyloepimetaphyseal dysplasia matrilin-3 related","type":"related"},{"name":"spondyloepimetaphyseal dysplasia matrilin-3 type","type":"related"},{"name":"spondyloepimetaphyseal dysplasia, Borochowitz-Cormier-Daire type","type":"exact"},{"name":"spondyloepimetaphyseal dysplasia, matrilin-3 related","type":"related"}],"termid":"MONDO:0012108","xrefs":{"Monarch":{"xref_id":"0012108"}}}


id: PBO:0048868
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A4","termid":"PBO:0048868"}


id: FYECO:0000313
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which TOP-53 (a drug that targets topoisomerase II) was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ TOP-53","termid":"FYECO:0000313"}


id: PBO:0000045
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase publication types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"null","termid":"PBO:0000045"}


id: PBO:0075652
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"splA/ryanodine receptor domain and SOCS box containing 1","termid":"PBO:0075652"}


id: PBO:0089131
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"helper of TIM Hot15","termid":"PBO:0089131"}


id: MONDO:0000754
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An intestinal disorder characterized by an opening in the anal canal to the perianal skin. In the vast majority of cases there is a history of perianal abscess.","definition_xrefs":["NCIT:C60785"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rectal disorder","termid":"MONDO:0001593"},{"relation_name":"is_a","term_name":"intestinal fistula","termid":"MONDO:1040017"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"anal fistula","secondary_identifiers":["MEDGEN:61482","ICD10CM:K60.3","GARD:20568","Orphanet:228113","SCTID:72779005","icd11.foundation:206903882","UMLS:C0205929","MESH:D012003","DOID:0060328","HP:0010447"],"synonyms":[{"name":"anal fistula","type":"exact"},{"name":"anal fistula (disease)","type":"exact"},{"name":"anorectal fistula","type":"exact"}],"termid":"MONDO:0000754","xrefs":{"Monarch":{"xref_id":"0000754"}}}


id: PBO:0065472
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome 26S subunit, non-ATPase, 10 pseudogene 3","termid":"PBO:0065472"}


id: PATO:0000536
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000536 water sensitivity value (obsolete PATO:0000536)","termid":"PATO:0000536"}


id: PBO:0084989
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADPH-dependent aldehyde reductase; utilizes aromatic and alophatic aldehyde substrates; member of the short-chain dehydrogenase/reductase superfamily","termid":"PBO:0084989"}


id: PBO:0053460
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 415","termid":"PBO:0053460"}


id: GO:0061250
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation involved in mesonephros development","termid":"GO:0061208"},{"relation_name":"is_a","term_name":"glomerular epithelial cell differentiation","termid":"GO:0072311"},{"relation_name":"part_of","term_name":"mesonephric glomerular epithelium development","termid":"GO:0061232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric glomerular epithelial cell differentiation","termid":"GO:0061250"}


id: PBO:0034191
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-subject_participant_in","termid":"PBO:0034191"}


id: PBO:0031817
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_autophagy","termid":"PBO:0031817"}


id: GO:0044650
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adhesion of symbiont to host","termid":"GO:0044406"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"adhesion of symbiont to host cell","termid":"GO:0044650"}


id: MONDO:0019345
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Shigellosis is a bacterial infection leading to dysentery and is caused by Shigella, which are small, ubiquitous Gram-negative bacteria belonging to the enterobacteria family. There are four species: S. dysenteriae, S. flexneri, S. boydii and S. sonnei, all of which cause bacillary dysentery and are strictly limited to human hosts.","definition_xrefs":["Orphanet:810"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary bacterial infectious disease","termid":"MONDO:0000314"},{"relation_name":"is_a","term_name":"dysentery","termid":"MONDO:0001517"},{"relation_name":"is_a","term_name":"large intestine disorder","termid":"MONDO:0024634"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"shigellosis","secondary_identifiers":["ICD10CM:A03","DOID:12385","MedDRA:10017915","NCIT:C157978","icd11.foundation:2080365623","ICD9:004.0","MEDGEN:8513","MESH:D004405","ICD9:004.9","ICD9:004.3","ICD9:004","GARD:4818","ICD9:004.2","ICD9:004.1","SCTID:36188001","UMLS:C0013371","MedDRA:10054178","EFO:0005585"],"synonyms":[{"name":"Shigella boydii infectious disease","type":"narrow"},{"name":"Shigella dysentery","type":"related"},{"name":"Shigella flexneri infectious disease","type":"narrow"},{"name":"Shigella gastroenteritis","type":"exact"},{"name":"Shigella sonnei infectious disease","type":"narrow"},{"name":"bacillary dysentery","type":"exact"},{"name":"flexner's dysentery","type":"related"},{"name":"japanese dysentery","type":"related"},{"name":"shigellosis","type":"exact"}],"termid":"MONDO:0019345","xrefs":{"Monarch":{"xref_id":"0019345"}}}


id: FYPO:0002270
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased catalytic activity","termid":"FYPO:0000662"},{"relation_name":"is_a","term_name":"abnormal glutamate-ammonia ligase activity","termid":"FYPO:0002267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0000654","FYPO:0001985","FYPO:0000652","FYPO:0000661"],"is_obsolete":false,"name":"increased glutamate-ammonia ligase activity","synonyms":[{"name":"increased GS activity","type":"exact"},{"name":"increased glutamine synthetase activity","type":"exact"},{"name":"increased glutamylhydroxamic synthetase activity","type":"exact"}],"termid":"FYPO:0002270"}


id: PBO:0044111
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cancer/testis associated transcript 70","termid":"PBO:0044111"}


id: PATO:0000039
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A physical quality inhering in a bearer by virtue of the bearer's orientation in space.","definition_xrefs":["thesaurus.maths:thesaurus.maths"],"direct_ancestors":[{"relation_name":"is_a","term_name":"physical quality","termid":"PATO:0001018"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"direction","termid":"PATO:0000039"}


id: PBO:0034308
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_member","termid":"PBO:0034308"}


id: PBO:0042199
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin F","termid":"PBO:0042199"}


id: PBO:0078119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha variable 8-1","termid":"PBO:0078119"}


id: PBO:0043741
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 7A2","termid":"PBO:0043741"}


id: GO:0050593
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-N-methylcoclaurine + H+ + NADPH + O2 = (S)-3'-hydroxy-N-methylcoclaurine + H2O + NADP+.","definition_xrefs":["RHEA:16649","EC:1.14.14.102"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"N-methylcoclaurine 3'-monooxygenase activity","secondary_identifiers":["KEGG_REACTION:R05732","MetaCyc:1.14.13.71-RXN"],"synonyms":[{"name":"(S)-N-methylcoclaurine 3'-hydroxylase activity","type":"related"},{"name":"(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating)","type":"related"},{"name":"N-methylcoclaurine 3'-hydroxylase activity","type":"exact"},{"name":"cytochrome P450 80B1 activity","type":"related"}],"termid":"GO:0050593"}


id: FYPO:0002341
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic DNA damage checkpoint","termid":"FYPO:0000006"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000298","FYPO:0005447","FYPO:0001985","FYPO:0000631","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased duration of mitotic DNA damage checkpoint","synonyms":[{"name":"delayed mitotic DNA damage checkpoint deactivation","type":"exact"},{"name":"prolonged mitotic DNA damage checkpoint","type":"exact"}],"termid":"FYPO:0002341"}


id: PBO:0038822
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADAM metallopeptidase domain 28","termid":"PBO:0038822"}


id: PBO:0062238
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily BB member 1 pseudogene","termid":"PBO:0062238"}


id: PBO:0013006
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase allele types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unrecorded","termid":"PBO:0013006"}


id: PBO:0116403
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methylosome pICln ortholog, Saf5","termid":"PBO:0116403"}


id: MONDO:0001280
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inflammatory process that affects the choroid.","definition_xrefs":["NCIT:C35111"],"direct_ancestors":[{"relation_name":"is_a","term_name":"optic choroid disorder","termid":"MONDO:0001898"},{"relation_name":"is_a","term_name":"posterior uveitis","termid":"MONDO:0006918"},{"relation_name":"is_a","term_name":"vasculitis","termid":"MONDO:0018882"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"choroiditis","secondary_identifiers":["SCTID:16553002","DOID:11406","HP:0012123","icd11.foundation:1884626736","MEDGEN:40282","UMLS:C0008526","GARD:4457","MESH:D002833","NORD:1601","MedDRA:10036370","Orphanet:280892"],"synonyms":[{"name":"Choroiditides","type":"exact"},{"name":"Posterior Uveitis","type":"related"},{"name":"choroiditis","type":"exact"},{"name":"posterior uveitis","type":"related"},{"name":"posterior uveitis (disease)","type":"related"}],"termid":"MONDO:0001280","xrefs":{"Monarch":{"xref_id":"0001280"}}}


id: MONDO:0005519
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma arising in the renal pelvis. The majority of renal pelvis carcinomas are transitional cell and less frequently squamous cell carcinomas.","definition_xrefs":["EFO:0005582"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal carcinoma","termid":"MONDO:0005206"},{"relation_name":"is_a","term_name":"malignant renal pelvis neoplasm","termid":"MONDO:0044919"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240","MONDO:0004992"],"is_obsolete":false,"name":"renal pelvis carcinoma","secondary_identifiers":["NCIT:C6142","SCTID:363457009","UMLS:C1335749","ICD9:189.1","ICD10CM:C65","MEDGEN:235548","DOID:4919"],"synonyms":[{"name":"cancer of renal pelvis","type":"broad"},{"name":"carcinoma of kidney pelvis","type":"exact"},{"name":"carcinoma of renal pelvis","type":"exact"},{"name":"carcinoma of the kidney pelvis","type":"exact"},{"name":"carcinoma of the renal pelvis","type":"exact"},{"name":"kidney pelvis carcinoma","type":"exact"},{"name":"kidney renal pelvis cancer","type":"exact"},{"name":"malignant neoplasm of renal pelvis","type":"broad"},{"name":"malignant renal pelvis neoplasm","type":"broad"},{"name":"malignant tumour of renal pelvis","type":"broad"},{"name":"renal pelvis cancer","type":"broad"},{"name":"renal pelvis carcinoma","type":"exact"}],"termid":"MONDO:0005519","xrefs":{"Monarch":{"xref_id":"0005519"}}}


id: PBO:0040236
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activating transcription factor 6 beta","termid":"PBO:0040236"}


id: PR:Q9C105
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A histone deacetylase complex subunit SAP130 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chitinase-like protein PB1E7.04c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB1E7.04c","secondary_identifiers":["UniProtKB:Q9C105"],"synonyms":[{"name":"Spom972h-SAP130","type":"exact"}],"termid":"PR:Q9C105"}


id: GO:0072293
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity.","definition_xrefs":["GOC:mtg_kidney_jan10","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"specification of nephron tubule identity","termid":"GO:0072081"},{"relation_name":"is_a","term_name":"pattern specification involved in metanephros development","termid":"GO:0072268"},{"relation_name":"part_of","term_name":"proximal/distal pattern formation involved in metanephric nephron development","termid":"GO:0072272"},{"relation_name":"part_of","term_name":"metanephric nephron tubule formation","termid":"GO:0072289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"specification of metanephric nephron tubule identity","termid":"GO:0072293"}


id: MONDO:0009676
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive limb-girdle muscular dystrophy type 2B (LGMD2B) is a subtype of autosomal recessive limb-girdle muscular dystrophy characterized by an onset in late adolescence or early adulthood of slowly progressive, proximal weakness and atrophy of shoulder and pelvic girdle muscles. Cardiac and respiratory muscles are not involved. Hypertrophy of the calf muscles and highly elevated serum creatine kinase levels are frequently observed.","definition_xrefs":["Orphanet:268"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive limb-girdle muscular dystrophy","termid":"MONDO:0015152"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of dysferlin","termid":"MONDO:0016145"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive limb-girdle muscular dystrophy type 2B","secondary_identifiers":["DOID:0110276","MEDGEN:338149","SCTID:718179003","GARD:8574","MESH:C535899","NCIT:C142080","UMLS:C1850889","OMIM:253601"],"synonyms":[{"name":"DYSF autosomal recessive limb-girdle muscular dystrophy","type":"exact"},{"name":"LGMD2B","type":"exact"},{"name":"LGMD3","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy caused by mutation in DYSF","type":"exact"},{"name":"limb-girdle muscular dystrophy due to dysferlin deficiency","type":"exact"},{"name":"limb-girdle muscular dystrophy type 2B","type":"exact"},{"name":"limb-girdle muscular dystrophy type 3","type":"exact"},{"name":"limb-girdle muscular dystrophy, type 2B","type":"related"},{"name":"muscular dystrophy, limb-girdle, autosomal recessive 2","type":"exact"},{"name":"muscular dystrophy, limb-girdle, type 2B","type":"related"},{"name":"muscular dystrophy, limb-girdle, type 3","type":"related"}],"termid":"MONDO:0009676","xrefs":{"Monarch":{"xref_id":"0009676"}}}


id: GO:0120020
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.","definition_xrefs":["GOC:krc","PMID:24220498","PMID:25797198","PMID:20823909"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sterol transfer activity","termid":"GO:0120015"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0120013"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0120013","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"cholesterol transfer activity","secondary_identifiers":["GO:0017127","Reactome:R-HSA-265545","Reactome:R-HSA-5682111","Reactome:R-HSA-1454928","Reactome:R-HSA-265443","Reactome:R-HSA-216723","Reactome:R-HSA-266082","Reactome:R-HSA-8951850"],"synonyms":[{"name":"cholesterol carrier activity","type":"exact"},{"name":"cholesterol transporter activity","type":"broad"},{"name":"intermembrane cholesterol transfer activity","type":"narrow"}],"termid":"GO:0120020"}


id: GO:0097475
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.","definition_xrefs":["GOC:yaf","PMID:20711475","CL:0000100"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron migration","termid":"GO:0001764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"motor neuron migration","termid":"GO:0097475"}


id: PBO:0057414
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 548o-2","termid":"PBO:0057414"}


id: FYECO:0000177
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which zinc was added to the medium or assay buffers in a limiting quantity compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping limited","termid":"FYECO:0000011"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ limited zinc","synonyms":[{"name":"limited Zn added","type":"exact"}],"termid":"FYECO:0000177"}


id: PBO:0001751
data:
  {"annotation_feature_type":"gene","cv_name":"subunit_composition","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterotetrameric","termid":"PBO:0001751"}


id: MONDO:0021908
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Aplasia cutis congenita with with autosomal dominant inheritance with reduced penetrance.","definition_xrefs":["PMID:3906608"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aplasia cutis congenita","termid":"MONDO:0007145"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"aplasia cutis congenita dominant","secondary_identifiers":["GARD:751"],"termid":"MONDO:0021908","xrefs":{"Monarch":{"xref_id":"0021908"}}}


id: PBO:0043859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CRADD antisense RNA 1","termid":"PBO:0043859"}


id: PBO:0003513
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetraspan protein Dni2 (predicted)","termid":"PBO:0003513"}


id: PBO:0031618
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_transposition","termid":"PBO:0031618"}


id: CHEBI:49786
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nickel(2+)","termid":"CHEBI:49786"}


id: PBO:0079259
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetratricopeptide repeat domain 31","termid":"PBO:0079259"}


id: PBO:0004073
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diacylglycerol binding protein Bzz1 (predicted)","termid":"PBO:0004073"}


id: GO:0030785
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine.","definition_xrefs":["EC:2.1.1.127"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0003824","GO:0016741","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity","secondary_identifiers":["MetaCyc:2.1.1.127-RXN","RHEA:50996"],"synonyms":[{"name":"RuBisCO LSMT activity","type":"related"},{"name":"RuBisCO methyltransferase activity","type":"related"},{"name":"S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity","type":"related"},{"name":"S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity","type":"related"},{"name":"ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity","type":"related"},{"name":"ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity","type":"related"},{"name":"ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity","type":"related"}],"termid":"GO:0030785"}


id: SO:0000982
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transcription terminator that is not dependent upon Rho. Rather, the mRNA contains a sequence that allows it to base-pair with itself and make a stem-loop structure.","direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial_terminator","termid":"SO:0000614"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rho_independent_bacterial_terminator","synonyms":[{"name":"rho independent bacterial terminator","type":"exact"}],"termid":"SO:0000982"}


id: PBO:0077838
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TPBGL antisense RNA 1","termid":"PBO:0077838"}


id: GO:1905176
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.","definition_xrefs":["GOC:rph","PMID:19088079","GOC:TermGenie","GOC:BHF","GOC:BHF_miRNA","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cellular process","termid":"GO:0048522"},{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of vascular associated smooth muscle cell dedifferentiation","termid":"GO:1905174"},{"relation_name":"positively_regulates","term_name":"vascular associated smooth muscle cell dedifferentiation","termid":"GO:1990936"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of vascular associated smooth muscle cell dedifferentiation","synonyms":[{"name":"activation of vascular smooth muscle cell dedifferentiation","type":"narrow"},{"name":"positive regulation of vascular smooth muscle cell dedifferentiation","type":"exact"},{"name":"up regulation of vascular smooth muscle cell dedifferentiation","type":"exact"},{"name":"up-regulation of vascular smooth muscle cell dedifferentiation","type":"exact"},{"name":"upregulation of vascular smooth muscle cell dedifferentiation","type":"exact"}],"termid":"GO:1905176"}


id: PBO:0046879
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 8 member A4, pseudogene","termid":"PBO:0046879"}


id: GO:0075515
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The uptake of a virus into a host cell that begins when material is taken up into plasma membrane caveolae which then pinch off to form endocytic caveolar carriers containing the virus. The caveolar carriers then deliver their viral content to early endosomes, and the process ends when viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane.","definition_xrefs":["GOC:jl","VZ:976"],"gene_count":0,"genotype_count":0,"name":"obsolete viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane (obsolete GO:0075515)","synonyms":[{"name":"viral entry into host cell via caveolae-mediated endocytosis followed by genetic injection through the endosome membrane","type":"exact"},{"name":"viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane","type":"exact"}],"termid":"GO:0075515"}


id: PBO:0002738
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rhomboid family protease","termid":"PBO:0002738"}


id: GO:0018415
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.","definition_xrefs":["RESID:AA0292"],"gene_count":0,"genotype_count":0,"name":"obsolete iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide (obsolete GO:0018415)","synonyms":[{"name":"iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide","type":"exact"}],"termid":"GO:0018415"}


id: GO:0042882
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.","definition_xrefs":["GOC:jsg","GOC:mah","ISBN:0198506732","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arabinose transmembrane transport","termid":"GO:0015751"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0055085","GO:0051179"],"is_obsolete":false,"name":"L-arabinose transmembrane transport","synonyms":[{"name":"L-arabinose transport","type":"related"}],"termid":"GO:0042882"}


id: PBO:0042526
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin dependent kinase 3","termid":"PBO:0042526"}


id: GO:2000747
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm.","definition_xrefs":["GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of defecation","termid":"GO:2000293"},{"relation_name":"is_a","term_name":"regulation of defecation rhythm","termid":"GO:2000746"},{"relation_name":"negatively_regulates","term_name":"defecation rhythm","termid":"GO:0035882"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of defecation rhythm","synonyms":[{"name":"negative regulation of DMP","type":"exact"},{"name":"negative regulation of defecation behavior","type":"related"},{"name":"negative regulation of defecation cycle","type":"exact"},{"name":"negative regulation of defecation motor program","type":"exact"}],"termid":"GO:2000747"}


id: SO:0001759
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A pseudogene, deactivated from original state by mutation, fixed in a population,where the ortholog in a reference species such as mouse remains functional.","definition_xrefs":["SO:ke","GENCODE:http://www.gencodegenes.org/gencode_biotypes.html"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non_processed_pseudogene","termid":"SO:0001760"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unitary_pseudogene","synonyms":[{"name":"INSDC_feature:gene","type":"broad"},{"name":"INSDC_qualifier:unitary","type":"exact"},{"name":"disabled gene","type":"related"},{"name":"unitary pseudogene","type":"related"}],"termid":"SO:0001759"}


id: PBO:0077990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transformer 2 beta homolog","termid":"PBO:0077990"}


id: MONDO:0036212
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spastic paraparesis-cataracts-speech delay syndrome","secondary_identifiers":["GARD:18033","Orphanet:615938","OMIM:619338"],"synonyms":[{"name":"Fatty acyl-CoA reductase 1 superactivity","type":"exact"}],"termid":"MONDO:0036212","xrefs":{"Monarch":{"xref_id":"0036212"}}}


id: PBO:0090005
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial holo-[acyl-carrier-protein] synthase Ppt2","termid":"PBO:0090005"}


id: PBO:0039514
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 30B pseudogene 2","termid":"PBO:0039514"}


id: GO:0035126
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"genitalia morphogenesis","termid":"GO:0035112"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"post-embryonic genitalia morphogenesis","synonyms":[{"name":"post-embryonic genital morphogenesis","type":"related"}],"termid":"GO:0035126"}


id: PBO:0065014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxiredoxin 1","termid":"PBO:0065014"}


id: PR:O13351
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pmt3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13351"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-like protein pmt3/smt3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC365.06","synonyms":[{"name":"Spom972h-pmt3","type":"exact"}],"termid":"PR:O13351"}


id: MONDO:0012071
data:
  {"annotated_genes":["SJAG_01957"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85129],"is_not":false,"summary":null,"term":"MONDO:0012071"}]},"cv_name":"mondo","definition":"Any congenital generalized lipodystrophy in which the cause of the disease is a mutation in the AGPAT2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital generalized lipodystrophy","termid":"MONDO:0006536"},{"relation_name":"is_a","term_name":"Berardinelli-Seip congenital lipodystrophy","termid":"MONDO:0018883"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01957":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005093"],"is_obsolete":false,"name":"congenital generalized lipodystrophy type 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0111135","GARD:84","MEDGEN:318592","OMIM:608594","UMLS:C1720862"],"synonyms":[{"name":"AGPAT2 congenital generalised lipodystrophy (disease)","type":"exact"},{"name":"AGPAT2 congenital generalized lipodystrophy (disease)","type":"exact"},{"name":"AGPAT2-related Brunzell syndrome","type":"related"},{"name":"BSCL1","type":"exact"},{"name":"Berardinelli-Seip congenital lipodystrophy type 1","type":"related"},{"name":"Berardinelli-Seip congenital lipodystrophy, type 1","type":"exact"},{"name":"Brunzell syndrome AGPAT2-related","type":"exact"},{"name":"Brunzell syndrome, AGPAT2-related","type":"related"},{"name":"CGL1","type":"exact"},{"name":"congenital generalised lipodystrophy (disease) caused by mutation in AGPAT2","type":"exact"},{"name":"congenital generalized lipodystrophy (disease) caused by mutation in AGPAT2","type":"exact"},{"name":"congenital generalized lipodystrophy type 1","type":"exact"},{"name":"lipodystrophy, Berardinelli-Seip congenital, type 1","type":"related"},{"name":"lipodystrophy, congenital generalized, type 1","type":"related"}],"termid":"MONDO:0012071","terms_by_termid":{"MONDO:0012071":null},"xrefs":{"Monarch":{"xref_id":"0012071"}}}


id: GO:0061114
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the branches of the pancreas are generated and organized.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"morphogenesis of a branching epithelium","termid":"GO:0061138"},{"relation_name":"part_of","term_name":"pancreas morphogenesis","termid":"GO:0061113"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"branching involved in pancreas morphogenesis","termid":"GO:0061114"}


id: PBO:0079389
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tubulin beta 3 class III pseudogene 1","termid":"PBO:0079389"}


id: GO:0036433
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.","definition_xrefs":["RHEA:28122"],"direct_ancestors":[{"relation_name":"is_a","term_name":"undecaprenol kinase activity","termid":"GO:0009038"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016301","GO:0016740","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"di-trans, poly-cis-undecaprenol kinase activity","secondary_identifiers":["KEGG_REACTION:R05626","MetaCyc:UNDECAPRENOL-KINASE-RXN","EC:2.7.1.66"],"synonyms":[{"name":"ditrans,polycis-undecaprenol kinase activity","type":"related"}],"termid":"GO:0036433"}


id: PBO:0028697
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_degradation_of_middle_meiotic_gene_mRNA_during_late_meiosis","termid":"PBO:0028697"}


id: GO:2000601
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.","definition_xrefs":["PMID:21454476"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of Arp2/3 complex-mediated actin nucleation","termid":"GO:0034315"},{"relation_name":"is_a","term_name":"positive regulation of actin nucleation","termid":"GO:0051127"},{"relation_name":"positively_regulates","term_name":"Arp2/3 complex-mediated actin nucleation","termid":"GO:0034314"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0030036"},{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"positively_regulates","termid":"GO:0007010"}],"interesting_parent_ids":["GO:0007010","GO:0030036","GO:0008150"],"is_obsolete":false,"name":"positive regulation of Arp2/3 complex-mediated actin nucleation","synonyms":[{"name":"positive regulation of actin filament branch nucleation","type":"exact"},{"name":"positive regulation of branched actin filament nucleation","type":"exact"}],"termid":"GO:2000601"}


id: PBO:0060932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear factor of activated T cells 2 interacting protein","termid":"PBO:0060932"}


id: GO:0043469
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"D-xylose catabolic process","termid":"GO:0042843"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"regulation of D-xylose catabolic process","termid":"GO:0043469"}


id: PBO:0052963
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kynureninase pseudogene 3","termid":"PBO:0052963"}


id: PBO:0082088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS4 has a paralog, PRS2, that arose from the whole genome duplication; a missense mutation in the conserved residue R196 of its human homolog PRPS1 is pathogenic","termid":"PBO:0082088"}


id: GO:1901968
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity.","definition_xrefs":["GOC:TermGenie","PMID:23316050"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of polynucleotide 3'-phosphatase activity (obsolete GO:1901968)","synonyms":[{"name":"regulation of 2'(3')-polynucleotidase activity","type":"exact"},{"name":"regulation of 5'-polynucleotidekinase 3'-phosphatase activity","type":"exact"},{"name":"regulation of DNA 3'-phosphatase activity","type":"exact"},{"name":"regulation of deoxyribonucleate 3'-phosphatase activity","type":"exact"},{"name":"regulation of polynucleotide 3'-phosphohydrolase activity","type":"exact"}],"termid":"GO:1901968"}


id: GO:0045604
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of epidermal cell differentiation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of epithelial cell differentiation","termid":"GO:0030856"},{"relation_name":"is_a","term_name":"regulation of epidermis development","termid":"GO:0045682"},{"relation_name":"regulates","term_name":"epidermal cell differentiation","termid":"GO:0009913"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of epidermal cell differentiation","synonyms":[{"name":"regulation of hypodermal cell differentiation","type":"related"}],"termid":"GO:0045604"}


id: GO:0042698
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rhythmic process","termid":"GO:0048511"},{"relation_name":"is_a","term_name":"multicellular organismal reproductive process","termid":"GO:0048609"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ovulation cycle","termid":"GO:0042698"}


id: PBO:0064361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostate transmembrane protein, androgen induced 1","termid":"PBO:0064361"}


id: GO:0070191
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin.","definition_xrefs":["PMID:19049972","GOC:mcc","PMID:17535911"],"gene_count":0,"genotype_count":0,"name":"obsolete methionine-R-sulfoxide reductase activity (obsolete GO:0070191)","termid":"GO:0070191"}


id: MONDO:0002287
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A reactive inflammatory disorder affecting the bladder. It is characterized by the development of small cysts in the bladder wall. The cysts are lined by metaplastic glandular cells.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chronic cystitis","termid":"MONDO:0006030"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glandular cystitis","secondary_identifiers":["SCTID:72815004","UMLS:C0268837","DOID:2392","MEDGEN:82830","ICD9:595.89","NCIT:C39860"],"synonyms":[{"name":"cystitis glandularis","type":"related"}],"termid":"MONDO:0002287","xrefs":{"Monarch":{"xref_id":"0002287"}}}


id: MONDO:0010846
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary multiple osteochondromas","termid":"MONDO:0005508"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exostoses, multiple, type III","secondary_identifiers":["UMLS:C1838420","MEDGEN:333090","MESH:C563975","OMIM:600209","GARD:2206"],"synonyms":[{"name":"EXT3","type":"exact"},{"name":"exostoses, multiple, type 3","type":"related"},{"name":"exostoses, multiple, type III","type":"exact"}],"termid":"MONDO:0010846","xrefs":{"Monarch":{"xref_id":"0010846"}}}


id: FYPO:0002204
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that each contain one or more septa, and in which the cell diameter is larger than normal and the cell length is shorter than normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical.","definition_xrefs":["PomBase:mah","PomBase:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable microcolony, stubby septated cells (obsolete FYPO:0002204)","synonyms":[{"name":"inviable microcolony, stubby septated vegetative cells","type":"exact"}],"termid":"FYPO:0002204"}


id: PR:O94447
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- slm1 gene.","definition_xrefs":["UniProtKB:O94447","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytoskeletal signaling protein slm1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC637.13c","synonyms":[{"name":"Spom972h-slm1","type":"exact"}],"termid":"PR:O94447"}


id: GO:0033819
data:
  {"annotated_genes":["SJAG_01271"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[97364],"is_not":false,"summary":null,"term":"GO:0033819"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysyl-[protein] + octanoyl-[ACP] = H+ + holo-[ACP] + N6-octanoyl-L-lysyl-[protein].","definition_xrefs":["RHEA:17665"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, transferring groups other than amino-acyl groups","termid":"GO:0016747"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a protein","termid":"GO:0140096"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01271":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0140096","GO:0016746","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"lipoyl(octanoyl) transferase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:RXN0-947","Reactome:R-HSA-6793590","EC:2.3.1.181","GO:0102555"],"synonyms":[{"name":"lipoate/octanoate transferase activity","type":"exact"},{"name":"lipoyl (octanoyl)-acyl carrier protein:protein transferase activity","type":"exact"},{"name":"lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity","type":"exact"},{"name":"octanoyl transferase activity (acting on glycine-cleavage complex H protein)","type":"narrow"},{"name":"octanoyl-acyl carrier protein-protein N-octanoyltransferase activity","type":"exact"},{"name":"octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity","type":"exact"},{"name":"octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity","type":"exact"}],"termid":"GO:0033819","terms_by_termid":{"GO:0033819":null}}


id: MONDO:0006821
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A complication of kidney diseases characterized by cell death involving kidney papilla in the kidney medulla. Damages to this area may hinder the kidney to concentrate urine resulting in polyuria. Sloughed off necrotic tissue may block kidney pelvis or ureter. Necrosis of multiple renal papillae can lead to kidney failure.","definition_xrefs":["MESH:D007681"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney disorder","termid":"MONDO:0005240"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"kidney papillary necrosis","secondary_identifiers":["DOID:2981","MedDRA:10028865","SCTID:90241004","MEDGEN:7212","UMLS:C0022667","ICD9:583.7"],"synonyms":[{"name":"necrotizing renal papillitis","type":"exact"},{"name":"papillary necrosis","type":"exact"},{"name":"renal papillitis necrotizing","type":"exact"}],"termid":"MONDO:0006821","xrefs":{"Monarch":{"xref_id":"0006821"}}}


id: PBO:0083769
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential non-ATPase regulatory subunit of the 26S proteasome lid; similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control","termid":"PBO:0083769"}


id: PBO:0060803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit S6 pseudogene 1","termid":"PBO:0060803"}


id: PBO:0084150
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"High affinity methionine permease; integral membrane protein with 13 putative membrane-spanning regions; involved in both methionine and cysteine uptake; subject to transport-activity dependent, methionine-induced endocytosis, vacuolar delivery and degradation; starvation-induced endocytosis is transport-activity independent","termid":"PBO:0084150"}


id: MONDO:0800144
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autoimmune disease that is characterized by a lack of PD-1 on patient peripheral blood mononuclear cells (PBMCs) and reduced IFN production in response to mycobacterial stimuli.","definition_xrefs":["PMID:34183838"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune disease","termid":"MONDO:0007179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"autoimmune pulmonary disease due to PD-1 deficiency","termid":"MONDO:0800144","xrefs":{"Monarch":{"xref_id":"0800144"}}}


id: MONDO:0035664
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"eye degenerative disorder","termid":"MONDO:0004884"},{"relation_name":"is_a","term_name":"neuromyelitis optica","termid":"MONDO:0019100"},{"relation_name":"is_a","term_name":"myelin oligodendrocyte glycoprotein antibody-associated disease","termid":"MONDO:1040024"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005559"],"is_obsolete":false,"name":"neuromyelitis optica spectrum disorder with anti-MOG antibodies","secondary_identifiers":["MEDGEN:1843203","UMLS:C5680296","ICD10CM:G36.0","Orphanet:592856","icd11.foundation:605048789","GARD:22373"],"synonyms":[{"name":"NMOSD with anti-MOG antibodies","type":"exact"},{"name":"Neuromyelitis optica spectrum disorder with anti-myelin oligodendrocyte glycoprotein antibodies","type":"exact"}],"termid":"MONDO:0035664","xrefs":{"Monarch":{"xref_id":"0035664"}}}


id: PBO:0064789
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase, Mg2+/Mn2+ dependent 1J","termid":"PBO:0064789"}


id: GO:0072373
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete alpha-carotene epsilon hydroxylase activity (obsolete GO:0072373)","termid":"GO:0072373"}


id: MONDO:0958228
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0006025"],"is_obsolete":false,"name":"hearing loss, autosomal recessive 122","secondary_identifiers":["OMIM:620714"],"synonyms":[{"name":"deafness, autosomal recessive 122","type":"narrow"}],"termid":"MONDO:0958228","xrefs":{"Monarch":{"xref_id":"0958228"}}}


id: PATO:0001039
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001039 absolute ratio (obsolete PATO:0001039)","termid":"PATO:0001039"}


id: PBO:0017414
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-preceded_by","termid":"PBO:0017414"}


id: PBO:0048295
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanidinoacetate N-methyltransferase pseudogene 2","termid":"PBO:0048295"}


id: FYECO:0000397
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which micafungin was added to the medium or assay buffer in excess compared to standard medium or assay buffers at lethal dose for the assayed cell density.","definition_xrefs":["PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ micafungin","termid":"FYECO:0000395"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ micafungin LD","termid":"FYECO:0000397"}


id: GO:0009678
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate.","definition_xrefs":["GOC:mtg_transport","Wikipedia:Proton-pumping_pyrophosphatase"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proton transmembrane transporter activity","termid":"GO:0015078"},{"relation_name":"is_a","term_name":"primary active transmembrane transporter activity","termid":"GO:0015399"},{"relation_name":"is_a","term_name":"active monoatomic ion transmembrane transporter activity","termid":"GO:0022853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"diphosphate hydrolysis-driven proton transmembrane transporter activity","secondary_identifiers":["MetaCyc:TRANS-RXN-370","EC:7.1.3.1","RHEA:13973","TC:3.A.10"],"synonyms":[{"name":"H+-exporting diphosphatase","type":"related"},{"name":"PP(i) hydrolysis-driven proton transmembrane transporter activity","type":"exact"},{"name":"hydrogen-translocating pyrophosphatase activity","type":"related"},{"name":"proton-pumping diphosphatase","type":"related"},{"name":"proton-pumping pyrophosphatase","type":"related"},{"name":"proton-translocating pyrophosphatase activity","type":"exact"},{"name":"pyrophosphate hydrolysis-driven proton transmembrane transporter activity","type":"related"}],"termid":"GO:0009678"}


id: MONDO:0000831
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The formation of a blood clot in the lumen of a vessel or heart chamber; causes include coagulation disorders and vascular endothelial injury.","definition_xrefs":["NCIT:C26891"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vascular disorder","termid":"MONDO:0005385"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombotic disease","secondary_identifiers":["MESH:D013927","SCTID:439127006","UMLS:C0040053","DOID:0060903","ICD9:453.9","MEDGEN:21160"],"synonyms":[{"name":"Clots, blood","type":"exact"},{"name":"Thromboses","type":"exact"},{"name":"blood Clots","type":"exact"},{"name":"blood clot","type":"exact"},{"name":"clot, blood","type":"exact"},{"name":"thrombosis","type":"exact"},{"name":"thrombotic disorder","type":"exact"},{"name":"thrombus","type":"exact"}],"termid":"MONDO:0000831","xrefs":{"Monarch":{"xref_id":"0000831"}}}


id: GO:0035375
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme binding","termid":"GO:0019899"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"zymogen binding","synonyms":[{"name":"proenzyme binding","type":"narrow"}],"termid":"GO:0035375"}


id: GO:1904461
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside.","definition_xrefs":["GO_REF:0000068","GOC:TermGenie","PMID:26116408"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid metabolic process","termid":"GO:0008202"},{"relation_name":"is_a","term_name":"saponin metabolic process","termid":"GO:0016134"},{"relation_name":"is_a","term_name":"beta-glucoside metabolic process","termid":"GO:1901804"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"ergosteryl 3-beta-D-glucoside metabolic process","synonyms":[{"name":"ergosteryl 3-beta-D-glucoside metabolism","type":"exact"}],"termid":"GO:1904461"}


id: GO:2000096
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of non-canonical Wnt signaling pathway","termid":"GO:2000052"},{"relation_name":"is_a","term_name":"regulation of Wnt signaling pathway, planar cell polarity pathway","termid":"GO:2000095"},{"relation_name":"positively_regulates","term_name":"Wnt signaling pathway, planar cell polarity pathway","termid":"GO:0060071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of Wnt signaling pathway, planar cell polarity pathway","synonyms":[{"name":"positive regulation of PCP pathway","type":"exact"},{"name":"positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway","type":"exact"},{"name":"positive regulation of Wnt receptor signalling pathway, planar cell polarity pathway","type":"exact"},{"name":"positive regulation of Wnt-JNK signaling pathway","type":"related"},{"name":"positive regulation of Wnt-PCP signaling pathway","type":"related"},{"name":"positive regulation of Wnt-activated signaling pathway, planar cell polarity pathway","type":"exact"},{"name":"positive regulation of non-canonical Wnt signaling pathway","type":"related"}],"termid":"GO:2000096"}


id: PBO:0012315
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyridoxal family membrane transporter (predicted)","termid":"PBO:0012315"}


id: MONDO:0004141
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"melanoma","termid":"MONDO:0005105"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"melanomatosis","secondary_identifiers":["DOID:7206","MEDGEN:235317","UMLS:C1334691","NCIT:C9499"],"synonyms":[{"name":"melanomatosis","type":"exact"}],"termid":"MONDO:0004141","xrefs":{"Monarch":{"xref_id":"0004141"}}}


id: PBO:0091293
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA initiator Methionine","termid":"PBO:0091293"}


id: PBO:0040096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP-ribosyltransferase 2, pseudogene","termid":"PBO:0040096"}


id: MONDO:0010620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary renal hypouricemia","termid":"MONDO:0009071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"hypouricemia, familial renal, due to tubular hypersecretion","secondary_identifiers":["MEDGEN:334869","UMLS:C1843972","GARD:15296","MESH:C564405","OMIM:307830"],"synonyms":[{"name":"hypouricemia, familial renal, due to tubular hypersecretion","type":"exact"}],"termid":"MONDO:0010620","xrefs":{"Monarch":{"xref_id":"0010620"}}}


id: PBO:0091028
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynactin complex actin-like protein Arp10","termid":"PBO:0091028"}


id: FYPO:0005436
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal double-strand break repair during vegetative growth","termid":"FYPO:0000777"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000002","FYPO:0000298","FYPO:0000293"],"is_obsolete":false,"name":"abolished double-strand break repair","synonyms":[{"name":"abolished double-strand break repair during mitotic cell cycle","type":"related"},{"name":"abolished double-strand break repair during vegetative growth","type":"exact"},{"name":"double-strand break repair abolished","type":"exact"}],"termid":"FYPO:0005436"}


id: PBO:0060145
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial transcription rescue factor 1","termid":"PBO:0060145"}


id: PBO:0034062
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-existence_ends_during_or_before","termid":"PBO:0034062"}


id: GO:0032239
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of transport","termid":"GO:0051049"},{"relation_name":"regulates","term_name":"nucleobase-containing compound transport","termid":"GO:0015931"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of nucleobase-containing compound transport","synonyms":[{"name":"regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport","type":"related"}],"termid":"GO:0032239"}


id: FYPO:0006401
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more 2'-deoxyribonucleoside triphosphates (dNTPs) measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell during vegetative growth","termid":"FYPO:0001329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased cellular dNTP level","synonyms":[{"name":"decreased cellular dNTP level during mitotic cell cycle","type":"related"},{"name":"decreased cellular dNTP level during vegetative growth","type":"exact"},{"name":"decreased dNTP accumulation","type":"related"},{"name":"reduced cellular dNTP level","type":"exact"}],"termid":"FYPO:0006401"}


id: FYPO:0007203
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of DNA binding at an rDNA spacer replication fork barrier by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah","PMID:18794373"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased double-stranded DNA binding","termid":"FYPO:0005018"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000653"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000707","FYPO:0000653","FYPO:0000652"],"is_obsolete":false,"name":"decreased rDNA spacer replication fork barrier binding","synonyms":[{"name":"decreased DNA binding at rDNA spacer replication fork barrier","type":"exact"},{"name":"reduced rDNA spacer replication fork barrier binding","type":"exact"}],"termid":"FYPO:0007203"}


id: PBO:0109122
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Glycoside Hydrolase family Sixteen","termid":"PBO:0109122"}


id: PATO:0001636
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A necessity quality (continuant) inhering in a bearer by virtue of the bearer's being non-essential or dispensable.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"necessity (continuant)","termid":"PATO:0001634"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unnecessary (continuant)","termid":"PATO:0001636"}


id: GO:0061308
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.","definition_xrefs":["GOC:mtg_heart","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neural crest cell development","termid":"GO:0014032"},{"relation_name":"part_of","term_name":"cardiac neural crest cell differentiation involved in heart development","termid":"GO:0061307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac neural crest cell development involved in heart development","termid":"GO:0061308"}


id: PBO:0051496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobin superfamily member 21","termid":"PBO:0051496"}


id: PBO:0027521
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cell_cycle","termid":"PBO:0027521"}


id: PBO:0061136
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NME/NM23 nucleoside diphosphate kinase 2","termid":"PBO:0061136"}


id: MONDO:0700010
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chromosomal disorder in which chromosome 3 is affected.","definition_xrefs":["MONDO:patterns/chromosome_type"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal anomaly","termid":"MONDO:0020049"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 3 disorder","termid":"MONDO:0700010","xrefs":{"Monarch":{"xref_id":"0700010"}}}


id: PBO:0088184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Zinc-finger DNA-binding transcription factor; involved in transcriptional regulation of the methionine biosynthetic genes; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; lack of such a loop for MET31 may account for the differential actions of Met32p and Met31p; MET32 has a paralog, MET31, that arose from the whole genome duplication","termid":"PBO:0088184"}


id: PBO:0050712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HSPB1 associated protein 1","termid":"PBO:0050712"}


id: PBO:0083929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fungal-specific protein of unknown function","termid":"PBO:0083929"}


id: SO:0001262
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A continous experimental result region extending the length of multiple overlapping EST's.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"has_part","term_name":"EST","termid":"SO:0000345"},{"relation_name":"is_a","term_name":"overlapping_feature_set","termid":"SO:0001261"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"overlapping_EST_set","synonyms":[{"name":"overlapping EST set","type":"exact"}],"termid":"SO:0001262"}


id: GO:0035798
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.","definition_xrefs":["PMID:16299173","RHEA:13737"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-alkenal reductase [NAD(P)+] activity","termid":"GO:0032440"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"2-alkenal reductase (NADPH) activity","secondary_identifiers":["EC:1.3.1.102"],"synonyms":[{"name":"NADPH:2-alkenal alpha,beta-hydrogenase activity","type":"exact"}],"termid":"GO:0035798"}


id: PBO:0077693
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tyrosine kinase non receptor 1","termid":"PBO:0077693"}


id: FYECO:0000231
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which sodium sulfite (Na2SO3) was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ Na2SO3","synonyms":[{"name":"sodium sulfite added","type":"exact"}],"termid":"FYECO:0000231"}


id: MONDO:0000405
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the anal canal","direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal cancer","termid":"MONDO:0005814"},{"relation_name":"is_a","term_name":"large intestine disorder","termid":"MONDO:0024634"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"anal canal cancer","secondary_identifiers":["SCTID:363352004","UMLS:C0153445","MEDGEN:509296","DOID:0050688","ICD9:154.2"],"synonyms":[{"name":"anal canal cancer","type":"exact"},{"name":"cancer of anal canal","type":"exact"},{"name":"malignant anal canal neoplasm","type":"exact"},{"name":"malignant neoplasm of anal canal","type":"exact"}],"termid":"MONDO:0000405","xrefs":{"Monarch":{"xref_id":"0000405"}}}


id: MONDO:0013242
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any maturity-onset diabetes of the young in which the cause of the disease is a mutation in the BLK gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maturity-onset diabetes of the young","termid":"MONDO:0018911"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005015"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0019254"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0005015","MONDO:0004335","MONDO:0005066","MONDO:0019254"],"is_obsolete":false,"name":"maturity-onset diabetes of the young type 11","secondary_identifiers":["SCTID:609578001","MEDGEN:461968","OMIM:613375","GARD:15653","UMLS:C3150618","DOID:0111109"],"synonyms":[{"name":"BLK maturity-onset diabetes of the young (disease)","type":"exact"},{"name":"MODY11","type":"exact"},{"name":"maturity-onset diabetes of the young (disease) caused by mutation in BLK","type":"exact"},{"name":"maturity-onset diabetes of the young, type 11","type":"related"}],"termid":"MONDO:0013242","xrefs":{"Monarch":{"xref_id":"0013242"}}}


id: PBO:0084102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport and for autophagy; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles","termid":"PBO:0084102"}


id: PBO:0074243
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 52 member 3","termid":"PBO:0074243"}


id: GO:0016836
data:
  {"annotated_genes":["SJAG_00337","SJAG_03669","SJAG_04843","SJAG_02988","SJAG_00305","SJAG_04404","SJAG_01574","SJAG_04674","SJAG_00461","SJAG_03124","SJAG_03588","SJAG_01372","SJAG_03213","SJAG_04098","SJAG_00592","SJAG_06611","SJAG_02293","SJAG_02084","SJAG_02689","SJAG_05007","SJAG_01630","SJAG_02107","SJAG_04107","SJAG_05283","SJAG_01300","SJAG_03243","SJAG_02106","SJAG_02369"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[100234,101541],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019171"},{"annotations":[90612],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003855"},{"annotations":[100318],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003861"},{"annotations":[93965,112896],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003994"},{"annotations":[117060],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0047453"},{"annotations":[112947],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004089"},{"annotations":[90203],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004160"},{"annotations":[115190],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004333"},{"annotations":[91954,87490,92633,92634,112256],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019172"},{"annotations":[96179],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004409"},{"annotations":[106404],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004424"},{"annotations":[92167,100149],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046570"},{"annotations":[104932,104930,104931],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004634"},{"annotations":[90483],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004655"},{"annotations":[108070],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004664"},{"annotations":[104968],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004730"},{"annotations":[91418],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061503"},{"annotations":[91086],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004834"},{"annotations":[95876],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004852"},{"annotations":[105356],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102158"}]},"cv_name":"molecular_function","definition":"Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.","definition_xrefs":["EC:4.2.1.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-oxygen lyase activity","termid":"GO:0016835"}],"gene_count":28,"genes_by_uniquename":{"SJAG_00305":null,"SJAG_00337":null,"SJAG_00461":null,"SJAG_00592":null,"SJAG_01300":null,"SJAG_01372":null,"SJAG_01574":null,"SJAG_01630":null,"SJAG_02084":null,"SJAG_02106":null,"SJAG_02107":null,"SJAG_02293":null,"SJAG_02369":null,"SJAG_02689":null,"SJAG_02988":null,"SJAG_03124":null,"SJAG_03213":null,"SJAG_03243":null,"SJAG_03588":null,"SJAG_03669":null,"SJAG_04098":null,"SJAG_04107":null,"SJAG_04404":null,"SJAG_04674":null,"SJAG_04843":null,"SJAG_05007":null,"SJAG_05283":null,"SJAG_06611":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"hydro-lyase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-2161659","Reactome:R-HSA-9014627"],"termid":"GO:0016836","terms_by_termid":{"GO:0003855":null,"GO:0003861":null,"GO:0003994":null,"GO:0004089":null,"GO:0004160":null,"GO:0004333":null,"GO:0004409":null,"GO:0004424":null,"GO:0004634":null,"GO:0004655":null,"GO:0004664":null,"GO:0004730":null,"GO:0004834":null,"GO:0004852":null,"GO:0019171":null,"GO:0019172":null,"GO:0046570":null,"GO:0047453":null,"GO:0061503":null,"GO:0102158":null}}


id: MONDO:0042499
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete benign familial neonatal-infantile seizures (obsolete MONDO:0011140)","termid":"MONDO:0011140"},{"relation_name":"is_a","term_name":"benign familial infantile epilepsy","termid":"MONDO:0017615"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"benign familial neonatal-infantile seizures 1","secondary_identifiers":["DOID:0081114","GARD:856","OMIM:601764","UMLS:C4551769","MEDGEN:1638448"],"synonyms":[{"name":"BFIC1","type":"related"},{"name":"BFIS1","type":"related"},{"name":"benign familial infantile convulsions syndrome","type":"related"},{"name":"benign familial infantile convulsions syndrome 1","type":"related"},{"name":"benign infantile familial convulsions","type":"related"},{"name":"benign infantile familial convulsions 1","type":"related"},{"name":"convulsions, benign familial infantile, 1","type":"related"},{"name":"seizures, benign familial infantile, 1","type":"related"}],"termid":"MONDO:0042499","xrefs":{"Monarch":{"xref_id":"0042499"}}}


id: PBO:0065954
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAD21 antisense RNA 1","termid":"PBO:0065954"}


id: MONDO:0012144
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Waardenburg syndrome type 2 in which the cause of the disease is a mutation in the SNAI2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Waardenburg syndrome type 2","termid":"MONDO:0019517"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"Waardenburg syndrome type 2D","secondary_identifiers":["MESH:C563839","DOID:0110952","OMIM:608890","MEDGEN:323102","UMLS:C1837203"],"synonyms":[{"name":"SNAI2 Waardenburg syndrome type 2","type":"exact"},{"name":"WS2D","type":"exact"},{"name":"Waardenburg syndrome type 2 caused by mutation in SNAI2","type":"exact"},{"name":"Waardenburg syndrome type IID","type":"exact"},{"name":"Waardenburg syndrome, type 2D","type":"related"}],"termid":"MONDO:0012144","xrefs":{"Monarch":{"xref_id":"0012144"}}}


id: RO:0002014
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.","direct_ancestors":[{"relation_name":"is_a","term_name":"has_regulatory_component_activity","termid":"RO:0002013"},{"relation_name":"is_a","term_name":"negatively_regulated_by","termid":"RO:0002335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_negative_regulatory_component_activity","termid":"RO:0002014"}


id: PBO:0078058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 48","termid":"PBO:0078058"}


id: GO:0061721
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).","definition_xrefs":["PMID:14602517","GOC:dph","PMID:24463506"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alkanesulfonate metabolic process","termid":"GO:0019694"},{"relation_name":"is_a","term_name":"propanediol metabolic process","termid":"GO:0051143"},{"relation_name":"is_a","term_name":"6-sulfoquinovose(1-) catabolic process","termid":"GO:1902777"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044248"}],"interesting_parent_ids":["GO:0006790","GO:0008150","GO:0044281","GO:0044248"],"is_obsolete":false,"name":"6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)","secondary_identifiers":["MetaCyc:PWY-7446"],"termid":"GO:0061721"}


id: SO:0001745
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Uniparental disomy is a sequence_alteration where a diploid individual receives two copies for all or part of a chromosome from the mother and no copies of the same chromosome or region from the father.","definition_xrefs":["SO:bm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UPD","termid":"SO:0001744"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"maternal_uniparental_disomy","synonyms":[{"name":"maternal uniparental disomy","type":"exact"}],"termid":"SO:0001745"}


id: PBO:0071585
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L36a pseudogene 1","termid":"PBO:0071585"}


id: GO:1901988
data:
  {"annotated_genes":["SJAG_04699","SJAG_01873","SJAG_00169","SJAG_00991","SJAG_01855","SJAG_04597","SJAG_01680","SJAG_01076","SJAG_04394","SJAG_00318","SJAG_01679","SJAG_03529","SJAG_03898","SJAG_02723","SJAG_01082","SJAG_00600","SJAG_02266","SJAG_01010","SJAG_01044","SJAG_06592","SJAG_03942","SJAG_03927","SJAG_03026","SJAG_04259","SJAG_05346","SJAG_03854","SJAG_01297","SJAG_00486","SJAG_01708","SJAG_00364","SJAG_03353","SJAG_02098","SJAG_02592","SJAG_04671","SJAG_02451","SJAG_03681","SJAG_03126","SJAG_02858","SJAG_04140","SJAG_00623","SJAG_00429","SJAG_01330","SJAG_00883","SJAG_04999","SJAG_03160","SJAG_03591","SJAG_00327","SJAG_00526","SJAG_03720","SJAG_02332","SJAG_00082","SJAG_01515","SJAG_03327","SJAG_04943","SJAG_00071","SJAG_03067","SJAG_02074","SJAG_02169","SJAG_01677","SJAG_01837","SJAG_02026","SJAG_04884","SJAG_04287","SJAG_04126","SJAG_03602","SJAG_05373","SJAG_04280","SJAG_02771","SJAG_01146","SJAG_02336","SJAG_01605","SJAG_03695","SJAG_03073","SJAG_03048","SJAG_00640","SJAG_02576","SJAG_03438","SJAG_02392","SJAG_01084","SJAG_04332","SJAG_01210","SJAG_00996","SJAG_01118","SJAG_01205","SJAG_02563","SJAG_01429","SJAG_01401"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[106701,99088,113711,103377,113221,115344,107713,90237,111409],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:1902426"},{"annotations":[108772],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000077"},{"annotations":[113941,105785],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905318"},{"annotations":[92034],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044778"},{"annotations":[90940,106081,115503],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033315"},{"annotations":[106082,113701,115504,88573],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051598"},{"annotations":[116112,101287,105786],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033316"},{"annotations":[100027,100925,115448,89505,93914],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044878"},{"annotations":[91301,115678,106083,113912,101847,77532,79553,117151,110650,115449,93066,93444,108773,98690,113702],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044773"},{"annotations":[98691,93445,90941,102805,108774,93466,115505,116716,92035,100028,88632,107301,98857,116246,116547,111484,106084],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033314"},{"annotations":[101848,108346,115346,88458,101111],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031568"},{"annotations":[109132,90817],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031571"},{"annotations":[94045,97934,115450,95354],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031569"},{"annotations":[116461,91302,89724,90942,100543,93446,111180,106085,100029,88633,98859,88062,113703,108775,117152],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007095"},{"annotations":[88063,88634,106086,98692,111181,115507,98860,116548,92036,89959,101013,88679,101849,90943,107131,111485,95515,100348,115506,94046],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031573"},{"annotations":[105787,116115,90239,98932,113944,113225,114999,101288,109369],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007094"},{"annotations":[92346,101855],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001100"},{"annotations":[88459,91248,98377,108347,92831,91668],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000134"},{"annotations":[103982,95356,92718,100488,106116,89506,106479,108032,111271,111923,113913,115451,92430,110886,113704,111014,93874,93067],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010972"},{"annotations":[115452,111015],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110031"},{"annotations":[98198],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902103"},{"annotations":[115000,105788],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045841"},{"annotations":[93706],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0140499"},{"annotations":[113226],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1905326"},{"annotations":[116119],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0090267"},{"annotations":[100826],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:1905325"},{"annotations":[93707],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0090266"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition.","definition_xrefs":["GOC:TermGenie","PMID:22841721","GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell cycle process","termid":"GO:0010948"},{"relation_name":"is_a","term_name":"regulation of cell cycle phase transition","termid":"GO:1901987"},{"relation_name":"negatively_regulates","term_name":"cell cycle phase transition","termid":"GO:0044770"}],"gene_count":87,"genes_by_uniquename":{"SJAG_00071":null,"SJAG_00082":null,"SJAG_00169":null,"SJAG_00318":null,"SJAG_00327":null,"SJAG_00364":null,"SJAG_00429":null,"SJAG_00486":null,"SJAG_00526":null,"SJAG_00600":null,"SJAG_00623":null,"SJAG_00640":null,"SJAG_00883":null,"SJAG_00991":null,"SJAG_00996":null,"SJAG_01010":null,"SJAG_01044":null,"SJAG_01076":null,"SJAG_01082":null,"SJAG_01084":null,"SJAG_01118":null,"SJAG_01146":null,"SJAG_01205":null,"SJAG_01210":null,"SJAG_01297":null,"SJAG_01330":null,"SJAG_01401":null,"SJAG_01429":null,"SJAG_01515":null,"SJAG_01605":null,"SJAG_01677":null,"SJAG_01679":null,"SJAG_01680":null,"SJAG_01708":null,"SJAG_01837":null,"SJAG_01855":null,"SJAG_01873":null,"SJAG_02026":null,"SJAG_02074":null,"SJAG_02098":null,"SJAG_02169":null,"SJAG_02266":null,"SJAG_02332":null,"SJAG_02336":null,"SJAG_02392":null,"SJAG_02451":null,"SJAG_02563":null,"SJAG_02576":null,"SJAG_02592":null,"SJAG_02723":null,"SJAG_02771":null,"SJAG_02858":null,"SJAG_03026":null,"SJAG_03048":null,"SJAG_03067":null,"SJAG_03073":null,"SJAG_03126":null,"SJAG_03160":null,"SJAG_03327":null,"SJAG_03353":null,"SJAG_03438":null,"SJAG_03529":null,"SJAG_03591":null,"SJAG_03602":null,"SJAG_03681":null,"SJAG_03695":null,"SJAG_03720":null,"SJAG_03854":null,"SJAG_03898":null,"SJAG_03927":null,"SJAG_03942":null,"SJAG_04126":null,"SJAG_04140":null,"SJAG_04259":null,"SJAG_04280":null,"SJAG_04287":null,"SJAG_04332":null,"SJAG_04394":null,"SJAG_04597":null,"SJAG_04671":null,"SJAG_04699":null,"SJAG_04884":null,"SJAG_04943":null,"SJAG_04999":null,"SJAG_05346":null,"SJAG_05373":null,"SJAG_06592":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"negative regulation of cell cycle phase transition","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"down regulation of cell cycle phase transition","type":"exact"},{"name":"down regulation of cell cycle transition","type":"exact"},{"name":"down-regulation of cell cycle phase transition","type":"exact"},{"name":"down-regulation of cell cycle transition","type":"exact"},{"name":"downregulation of cell cycle phase transition","type":"exact"},{"name":"downregulation of cell cycle transition","type":"exact"},{"name":"inhibition of cell cycle phase transition","type":"narrow"},{"name":"inhibition of cell cycle transition","type":"exact"},{"name":"negative regulation of cell cycle transition","type":"exact"}],"termid":"GO:1901988","terms_by_termid":{"GO:0000077":null,"GO:0001100":null,"GO:0007094":null,"GO:0007095":null,"GO:0010972":null,"GO:0031568":null,"GO:0031569":null,"GO:0031571":null,"GO:0031573":null,"GO:0033314":null,"GO:0033315":null,"GO:0033316":null,"GO:0044773":null,"GO:0044778":null,"GO:0044878":null,"GO:0045841":null,"GO:0051598":null,"GO:0090266":null,"GO:0090267":null,"GO:0110031":null,"GO:0140499":null,"GO:1902103":null,"GO:1902426":null,"GO:1905318":null,"GO:1905325":null,"GO:1905326":null,"GO:2000134":null}}


id: PBO:0059534
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded transcription terminator","termid":"PBO:0059534"}


id: MONDO:0001694
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"interstitial keratitis","termid":"MONDO:0004902"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"diffuse interstitial keratitis","secondary_identifiers":["UMLS:C0155089","ICD9:370.52","DOID:13353","icd11.foundation:1750662534","MEDGEN:509780","SCTID:17157001"],"termid":"MONDO:0001694","xrefs":{"Monarch":{"xref_id":"0001694"}}}


id: PBO:0061259
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"notch 2 N-terminal like B","termid":"PBO:0061259"}


id: PBO:0054493
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1893","termid":"PBO:0054493"}


id: PBO:0087263
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance","termid":"PBO:0087263"}


id: GO:0070686
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The portion of the plasma membrane surrounding a macropinocytic cup.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell projection membrane","termid":"GO:0031253"},{"relation_name":"part_of","term_name":"macropinocytic cup","termid":"GO:0070685"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"macropinocytic cup membrane","synonyms":[{"name":"crown membrane","type":"exact"}],"termid":"GO:0070686"}


id: MONDO:0019722
data:
  {"annotated_genes":["SJAG_04621","SJAG_00118","SJAG_01143","SJAG_04001"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84625],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011303"},{"annotations":[85467],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013589"},{"annotations":[86401,86402],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014462"}]},"cv_name":"mondo","definition":"A disease involving the renal glomerulus.","definition_xrefs":["MONDO:patterns/location_top"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney disorder","termid":"MONDO:0005240"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00118":null,"SJAG_01143":null,"SJAG_04001":null,"SJAG_04621":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"glomerular disorder","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:197679002","GTR:AN0966176","ICD10CM:N00-N08","NCIT:C120887","Orphanet:93548","EFO:1002049"],"synonyms":[{"name":"disease of renal glomerulus","type":"exact"},{"name":"disease or disorder of renal glomerulus","type":"exact"},{"name":"disorder of renal glomerulus","type":"exact"},{"name":"glomerulopathies","type":"related"},{"name":"glomerulopathy","type":"exact"},{"name":"renal glomerulus disease","type":"exact"},{"name":"renal glomerulus disease or disorder","type":"exact"}],"termid":"MONDO:0019722","terms_by_termid":{"MONDO:0011303":null,"MONDO:0013589":null,"MONDO:0014462":null},"xrefs":{"Monarch":{"xref_id":"0019722"}}}


id: GO:0004659
data:
  {"annotated_genes":["SJAG_03029","SJAG_02163","SJAG_02719","SJAG_02583","SJAG_06603","SJAG_03352","SJAG_04434","SJAG_03173","SJAG_01865","SJAG_03810","SJAG_04923","SJAG_04568","SJAG_00554","SJAG_00580"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[99097,108941],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004337"},{"annotations":[97894],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008412"},{"annotations":[91339,119009,113189,119010],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0097269"},{"annotations":[95222,95223,100889],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004662"},{"annotations":[107481,97280],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045547"},{"annotations":[99098,108942],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004311"},{"annotations":[90066,90067,100890,100891],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004660"},{"annotations":[100892],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004661"},{"annotations":[108988],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008495"},{"annotations":[114397,100893,89042],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004663"},{"annotations":[110762],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051996"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase activity, transferring alkyl or aryl (other than methyl) groups","termid":"GO:0016765"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00554":null,"SJAG_00580":null,"SJAG_01865":null,"SJAG_02163":null,"SJAG_02583":null,"SJAG_02719":null,"SJAG_03029":null,"SJAG_03173":null,"SJAG_03352":null,"SJAG_03810":null,"SJAG_04434":null,"SJAG_04568":null,"SJAG_04923":null,"SJAG_06603":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016765"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016765"],"is_obsolete":false,"name":"prenyltransferase activity","references_by_uniquename":{"GO_REF:0000107":null,"PMID:29191091":null},"secondary_identifiers":["Reactome:R-HSA-6806674"],"termid":"GO:0004659","terms_by_termid":{"GO:0004311":null,"GO:0004337":null,"GO:0004660":null,"GO:0004661":null,"GO:0004662":null,"GO:0004663":null,"GO:0006743":null,"GO:0006744":null,"GO:0008412":null,"GO:0008495":null,"GO:0045547":null,"GO:0051996":null,"GO:0097269":null}}


id: PBO:0050425
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein H2","termid":"PBO:0050425"}


id: GO:0016405
data:
  {"annotated_genes":["SJAG_00947","SJAG_03471","SJAG_03909","SJAG_02741"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[115541],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003987"},{"annotations":[115209],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031956"},{"annotations":[105067,112865],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090432"},{"annotations":[105068],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090434"},{"annotations":[115210],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0050203"},{"annotations":[105069],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090433"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ligase activity, forming carbon-sulfur bonds","termid":"GO:0016877"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00947":null,"SJAG_02741":null,"SJAG_03471":null,"SJAG_03909":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016874"}],"interesting_parent_ids":["GO:0016874","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"CoA-ligase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-9749971","Reactome:R-HSA-159567","Reactome:R-HSA-159443","Reactome:R-HSA-6798345","Reactome:R-HSA-177157"],"termid":"GO:0016405","terms_by_termid":{"GO:0003987":null,"GO:0031956":null,"GO:0050203":null,"GO:0090432":null,"GO:0090433":null,"GO:0090434":null}}


id: SO:0000704
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions.","definition_xrefs":["SO:immuno_workshop"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological_region","termid":"SO:0001411"},{"relation_name":"member_of","term_name":"gene_group","termid":"SO:0005855"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gene","secondary_identifiers":["http://en.wikipedia.org/wiki/Gene"],"synonyms":[{"name":"INSDC_feature:gene","type":"exact"}],"termid":"SO:0000704"}


id: MONDO:0004653
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A myelodysplastic/myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a Philadelphia chromosome or the BCR/ABL fusion gene. (WHO, 2001)","definition_xrefs":["NCIT:C3519"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid leukemia","termid":"MONDO:0004643"},{"relation_name":"is_a","term_name":"myelodysplastic/myeloproliferative neoplasm","termid":"MONDO:0006311"},{"relation_name":"is_a","term_name":"myelodysplastic/myeloproliferative disease","termid":"MONDO:0020077"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046","MONDO:0004992"],"is_obsolete":false,"name":"atypical chronic myeloid leukemia, BCR-ABL1 negative","secondary_identifiers":["GARD:19583","DOID:8747","ICDO:9876/3","SCTID:277589003","DOID:0060597","icd11.foundation:331838766","MedDRA:10054651","MEDGEN:266233","UMLS:C1292772","Orphanet:98824"],"synonyms":[{"name":"aCML","type":"exact"},{"name":"atypical CML","type":"exact"},{"name":"atypical chronic myeloid leukaemia","type":"exact"},{"name":"atypical chronic myeloid leukaemia BCR-ABL1 negative","type":"exact"},{"name":"atypical chronic myeloid leukemia","type":"exact"},{"name":"atypical chronic myeloid leukemia BCR-ABL1 negative","type":"exact"},{"name":"atypical chronic myeloid leukemia, BCR-ABL1 Negative","type":"exact"},{"name":"subacute granulocytic leukaemia","type":"exact"},{"name":"subacute granulocytic leukemia","type":"exact"},{"name":"subacute myelogenous leukaemia","type":"exact"},{"name":"subacute myelogenous leukemia","type":"exact"},{"name":"subacute myeloid leukaemia","type":"exact"},{"name":"subacute myeloid leukemia","type":"exact"}],"termid":"MONDO:0004653","xrefs":{"Monarch":{"xref_id":"0004653"}}}


id: PBO:0001319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RecA family","termid":"PBO:0001319"}


id: PBO:0080406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar protein sorting 36 homolog","termid":"PBO:0080406"}


id: GO:0061778
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.","definition_xrefs":["PMID:23092411","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete intracellular chloride channel activity (obsolete GO:0061778)","termid":"GO:0061778"}


id: PR:P40998
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- thi2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P40998"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thiamine thiazole synthase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC26H8.01","synonyms":[{"name":"Spom972h-thi2","type":"exact"},{"name":"thiazole biosynthetic enzyme (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P40998"}


id: MONDO:0015387
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nasolacrimal duct cyst describes a unilateral or bilateral congenital cyst of the nasolacrimal duct, which is almost always associated with dacryocystocele, presenting most commonly at birth or a few weeks of age (but rarely presenting in adulthood) as a benign, grayish blue mass in the inferomedial canthus or in the nasal cavity, that can cause epiphora, dacryocystitis (inflammation of the lacrimal sac) and nasal obstruction. It is more commonly reported in females.","definition_xrefs":["Orphanet:141083"],"direct_ancestors":[{"relation_name":"is_a","term_name":"otorhinolaryngologic disease","termid":"MONDO:0024623"},{"relation_name":"is_a","term_name":"nasolacrimal duct disorder","termid":"MONDO:0044984"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"nasolacrimal duct cyst","secondary_identifiers":["MEDGEN:1810477","UMLS:C5575612","GARD:19944"],"synonyms":[{"name":"dacryocele","type":"exact"},{"name":"dacryocystocele","type":"related"},{"name":"nasolacrimal mucocele","type":"exact"}],"termid":"MONDO:0015387","xrefs":{"Monarch":{"xref_id":"0015387"}}}


id: FYPO:0007409
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which alternative polyadenylation of mRNA is abnormal. mRNA alternative polyadenylation generates mRNA molecules with variable 3'-end lengths from a given pre-mRNA by differential use of cleavage and polyadenylation signals. Includes differences in the relative usage levels of alternative polyadenylation sites.","definition_xrefs":["PomBase:mah","GO:0110104"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal RNA alternative polyadenylation","termid":"FYPO:0007919"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000294"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000294","FYPO:0005447","FYPO:0000002","FYPO:0006551","FYPO:0001985"],"is_obsolete":false,"name":"abnormal mRNA alternative polyadenylation","synonyms":[{"name":"abnormal mRNA alternative polyadenylation during mitotic cell cycle","type":"related"},{"name":"abnormal mRNA alternative polyadenylation during vegetative growth","type":"exact"}],"termid":"FYPO:0007409"}


id: GO:0140586
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop.","definition_xrefs":["PMID:19933151"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromatin loop anchoring activity","termid":"GO:0140587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003677"}],"interesting_parent_ids":["GO:0060090","GO:0005488","GO:0003677","GO:0003674"],"is_obsolete":false,"name":"promoter-terminator loop anchoring activity","synonyms":[{"name":"terminator-promoter loop anchoring activity","type":"exact"}],"termid":"GO:0140586"}


id: MONDO:0012126
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Avascular necrosis of femoral head (ANFH) is a severely disabling disease characterized by progressive groin pain, a limping gait, leg length discrepancy, collapse of the subchondral bone, limitation of hip function and eventual degeneration of the hip joint requiring total hip arthroplasty.","definition_xrefs":["Orphanet:86820"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete type 2 collagen-related bone disorder (obsolete MONDO:0019686)","termid":"MONDO:0019686"},{"relation_name":"is_a","term_name":"primary avascular necrosis","termid":"MONDO:0018379"},{"relation_name":"is_a","term_name":"osteonecrosis of genetic origin","termid":"MONDO:0018383"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"familial avascular necrosis of femoral head","secondary_identifiers":["UMLS:C4275066","NCIT:C35480","NANDO:1200373","GARD:10914","MESH:D005271","icd11.foundation:1216860745","OMIMPS:608805","MEDGEN:909851","SCTID:715657008"],"synonyms":[{"name":"ANFH","type":"related"},{"name":"ANFH1","type":"related"},{"name":"aseptic Necrosis of femoral head","type":"exact"},{"name":"aseptic Necrosis of head of femur","type":"exact"},{"name":"avascular NECROSIS of femoral head, primary","type":"related"},{"name":"avascular NECROSIS of femoral head, primary, 1","type":"related"},{"name":"avascular Necrosis of femoral head, primary, 1","type":"related"},{"name":"familial avascular necrosis of the femoral head","type":"related"},{"name":"familial osteonecrosis of the femoral head","type":"exact"},{"name":"femoral head, aseptic Necrosis of","type":"related"},{"name":"femoral head, avascular Necrosis of","type":"related"},{"name":"ischaemic Necrosis of femoral head","type":"related"},{"name":"ischemic Necrosis of femoral head","type":"related"},{"name":"osteonecrosis of femoral head","type":"related"},{"name":"primary avascular necrosis of the femoral head","type":"related"}],"termid":"MONDO:0012126","xrefs":{"Monarch":{"xref_id":"0012126"}}}


id: PBO:0041014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BPI fold containing family A member 1","termid":"PBO:0041014"}


id: MONDO:0800268
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"familial atrioventricular septal defect","termid":"MONDO:0020290"},{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atrioventricular septal defect, susceptibility to, 1","secondary_identifiers":["MEDGEN:342900","UMLS:C1853513"],"synonyms":[{"name":"AVC defect","type":"related"},{"name":"AVSD","type":"related"},{"name":"AVSD1","type":"exact"},{"name":"atrioventricular canal defect","type":"related"},{"name":"atrioventricular septal defect","type":"related"},{"name":"endocardial cushion defect","type":"related"}],"termid":"MONDO:0800268","xrefs":{"Monarch":{"xref_id":"0800268"}}}


id: PBO:0072746
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S100 calcium binding protein A7 pseudogene 2","termid":"PBO:0072746"}


id: PBO:0016055
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mating type Auxiliary Plus","termid":"PBO:0016055"}


id: PBO:0070752
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L10 pseudogene 8","termid":"PBO:0070752"}


id: PBO:0063621
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphofructokinase, muscle","termid":"PBO:0063621"}


id: PBO:0040580
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BAALC antisense RNA 2","termid":"PBO:0040580"}


id: GO:0050289
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.","definition_xrefs":["MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN","EC:1.5.99.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors","termid":"GO:0016645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"spermidine dehydrogenase activity","secondary_identifiers":["RHEA:14273"],"synonyms":[{"name":"spermidine:(acceptor) oxidoreductase activity","type":"related"},{"name":"spermidine:acceptor oxidoreductase activity","type":"related"}],"termid":"GO:0050289"}


id: PBO:0077887
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TPRG1 antisense RNA 1","termid":"PBO:0077887"}


id: GO:0061007
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"system process","termid":"GO:0003008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hepaticobiliary system process","synonyms":[{"name":"hepatobiliary system process","type":"exact"}],"termid":"GO:0061007"}


id: PBO:0061402
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"natriuretic peptide receptor 3","termid":"PBO:0061402"}


id: PBO:0043926
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CROCC pseudogene 5","termid":"PBO:0043926"}


id: GO:0000336
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of DNA transposition.","definition_xrefs":["GOC:krc","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of transposition, DNA-mediated (obsolete GO:0000336)","synonyms":[{"name":"activation of DNA transposition","type":"narrow"},{"name":"positive regulation of DNA transposition","type":"exact"},{"name":"stimulation of DNA transposition","type":"narrow"},{"name":"up regulation of DNA transposition","type":"exact"},{"name":"up-regulation of DNA transposition","type":"exact"},{"name":"upregulation of DNA transposition","type":"exact"}],"termid":"GO:0000336"}


id: FYPO:0000290
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle that affects DNA-dependent transcription.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription phenotype","termid":"FYPO:0004847"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000294","FYPO:0000002"],"is_obsolete":false,"name":"transcription phenotype during vegetative growth","synonyms":[{"name":"transcription phenotype during mitotic cell cycle","type":"related"}],"termid":"FYPO:0000290"}


id: MONDO:0015974
data:
  {"annotated_genes":["SJAG_02527","SJAG_00677","SJAG_04199","SJAG_02038","SJAG_05024"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86316],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012650"},{"annotations":[86596],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011686"},{"annotations":[85177],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009973"},{"annotations":[85429],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014168"},{"annotations":[85980],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014391"}]},"cv_name":"mondo","definition":"Severe combined immunodeficiency (SCID) comprises a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T lymphocytes resulting in early-onset severe respiratory infections and failure to thrive. They are classified according to immunological phenotype into SCID with absence of T cells but presence of B cells (T-B+ SCID) or SCID with absence of both (T-B- SCID). Both of these groups include several forms, with or without natural killer (NK) cells.","definition_xrefs":["Orphanet:183660"],"direct_ancestors":[{"relation_name":"is_a","term_name":"combined immunodeficiency","termid":"MONDO:0015131"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00677":null,"SJAG_02038":null,"SJAG_02527":null,"SJAG_04199":null,"SJAG_05024":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"severe combined immunodeficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:88328","NORD:1706","MedDRA:10069566","MESH:D016511","NCIT:C3472","icd11.foundation:963193284","GARD:7628","HP:0004430","SCTID:31323000","DOID:627","UMLS:C0085110"],"synonyms":[{"name":"SCID","type":"exact"},{"name":"combined T and B cell inborn immunodeficiency","type":"exact"},{"name":"severe combined immunodeficiency","type":"exact"},{"name":"severe combined immunodeficiency (disease)","type":"exact"},{"name":"severe combined immunodeficiency disease","type":"exact"}],"termid":"MONDO:0015974","terms_by_termid":{"MONDO:0009973":null,"MONDO:0011686":null,"MONDO:0012650":null,"MONDO:0014168":null,"MONDO:0014391":null},"xrefs":{"Monarch":{"xref_id":"0015974"}}}


id: GO:0015859
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside transport","termid":"GO:0015858"},{"relation_name":"is_a","term_name":"intracellular transport","termid":"GO:0046907"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"intracellular nucleoside transport","termid":"GO:0015859"}


id: GO:0070224
data:
  {"annotated_genes":["SJAG_02599"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[107897],"is_not":false,"summary":null,"term":"GO:0070224"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: H2S (hydrogen sulfide) + a quinone = S0 (sulfane sulfur) + a hydroquinone.","definition_xrefs":["RHEA:30239"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor","termid":"GO:0016672"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02599":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"sulfide:quinone oxidoreductase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:R17-RXN","Reactome:R-HSA-1614665"],"synonyms":[{"name":"sulfide-quinone reductase activity","type":"exact"},{"name":"sulphide:quinone oxidoreductase activity","type":"exact"}],"termid":"GO:0070224","terms_by_termid":{"GO:0070224":null}}


id: GO:0030059
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H+ + NH4+ + 2 reduced [azurin].","definition_xrefs":["PMID:10506161","RHEA:47796"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor","termid":"GO:0052877"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"aralkylamine dehydrogenase (azurin) activity","secondary_identifiers":["MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN","EC:1.4.9.2"],"synonyms":[{"name":"aralkylamine:(azurin) oxidoreductase (deaminating) activity","type":"exact"},{"name":"aromatic amine dehydrogenase (azurin) activity","type":"exact"}],"termid":"GO:0030059"}


id: PBO:0079385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tubulin beta 2A class IIa","termid":"PBO:0079385"}


id: PBO:0080974
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger and BTB domain containing 9","termid":"PBO:0080974"}


id: PR:O74749
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- hse1 gene.","definition_xrefs":["UniProtKB:O74749","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"class E vacuolar protein-sorting machinery protein hse1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1734.08","synonyms":[{"name":"Spom972h-hse1","type":"exact"}],"termid":"PR:O74749"}


id: PBO:0005706
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCR4-Not complex CAF1 family ribonuclease subunit Caf1","termid":"PBO:0005706"}


id: GO:0018077
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The addition of one or more iodine atoms to an amino acid residue in a protein.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete protein iodination (obsolete GO:0018077)","synonyms":[{"name":"protein amino acid iodination","type":"exact"}],"termid":"GO:0018077"}


id: MONDO:0018485
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Glycogen storage disease due to acid maltase deficiency, late onset (AMDL), a form of Glycogen storage disease due to acid maltase deficiency (AMD), a degenerative metabolic myopathy particularly affecting respiratory and skeletal muscles, is characterized by an accumulation of glycogen in lysosomes.","definition_xrefs":["Orphanet:420429"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycogen storage disease II","termid":"MONDO:0009290"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002561","MONDO:0005267","MONDO:0037792"],"is_obsolete":false,"name":"glycogen storage disease due to acid maltase deficiency, late-onset","secondary_identifiers":["MEDGEN:575206","GARD:21746","UMLS:C0342753","SCTID:722343009"],"synonyms":[{"name":"Alpha-1,4-glucosidase acid deficiency, late onset","type":"exact"},{"name":"Alpha-1,4-glucosidase acid deficiency, late-onset","type":"exact"},{"name":"GSD due to acid maltase deficiency, late onset","type":"exact"},{"name":"GSD due to acid maltase deficiency, late-onset","type":"exact"},{"name":"GSD type 2, late onset","type":"exact"},{"name":"GSD type 2, late-onset","type":"exact"},{"name":"GSD type II, late onset","type":"exact"},{"name":"GSD type II, late-onset","type":"exact"},{"name":"LOPD","type":"exact"},{"name":"Pompe disease, late onset","type":"exact"},{"name":"Pompe disease, late-onset","type":"exact"},{"name":"glycogen storage disease type 2, late onset","type":"exact"},{"name":"glycogen storage disease type 2, late-onset","type":"exact"},{"name":"glycogen storage disease type II, late onset","type":"exact"},{"name":"glycogen storage disease type II, late-onset","type":"exact"},{"name":"glycogenosis type 2, late onset","type":"exact"},{"name":"glycogenosis type 2, late-onset","type":"exact"},{"name":"glycogenosis type II, late onset","type":"exact"},{"name":"glycogenosis type II, late-onset","type":"exact"}],"termid":"MONDO:0018485","xrefs":{"Monarch":{"xref_id":"0018485"}}}


id: GO:0062151
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein-containing complex that is capable of catalase activity.","definition_xrefs":["GOC:bhm","PMID:10656833"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase complex","termid":"GO:1990204"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"catalase complex","termid":"GO:0062151"}


id: GO:1901018
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity.","definition_xrefs":["GOC:BHF","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of ion transmembrane transporter activity","termid":"GO:0032414"},{"relation_name":"is_a","term_name":"regulation of potassium ion transmembrane transporter activity","termid":"GO:1901016"},{"relation_name":"is_a","term_name":"positive regulation of potassium ion transmembrane transport","termid":"GO:1901381"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"positively_regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of potassium ion transmembrane transporter activity","synonyms":[{"name":"activation of potassium ion transmembrane transporter activity","type":"narrow"},{"name":"activation of potassium transporter activity","type":"exact"},{"name":"positive regulation of potassium transporter activity","type":"exact"},{"name":"up regulation of potassium ion transmembrane transporter activity","type":"exact"},{"name":"up regulation of potassium transporter activity","type":"exact"},{"name":"up-regulation of potassium ion transmembrane transporter activity","type":"exact"},{"name":"up-regulation of potassium transporter activity","type":"exact"},{"name":"upregulation of potassium ion transmembrane transporter activity","type":"exact"},{"name":"upregulation of potassium transporter activity","type":"exact"}],"termid":"GO:1901018"}


id: PBO:0013775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy protein Atg11","termid":"PBO:0013775"}


id: GO:0141042
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The production by a symbiont of high levels of cyclic AMP in a host cell, impairing host cellular functions in multiple ways, including ATP depletion, interference with host intracellular signaling, cytoskeletal defects and apoptosis-related cell death. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:16390441","PMID:19516256","PMID:27731909","PMID:33013916"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host signal transduction pathway","termid":"GO:0052027"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated cAMP intoxication of host cell","synonyms":[{"name":"cAMP intoxication in host","type":"exact"}],"termid":"GO:0141042"}


id: PBO:0089453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylglycerol phospholipase C Pgc1 /SMN complex subunit Gem6, tandem fusion","termid":"PBO:0089453"}


id: GO:0003178
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the valve of the coronary sinus over time, from its formation to the mature structure.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart valve development","termid":"GO:0003170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"coronary sinus valve development","termid":"GO:0003178"}


id: PBO:0068929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 172, pseudogene","termid":"PBO:0068929"}


id: GO:2000828
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of endocrine process","termid":"GO:0044060"},{"relation_name":"is_a","term_name":"regulation of hormone secretion","termid":"GO:0046883"},{"relation_name":"regulates","term_name":"parathyroid hormone secretion","termid":"GO:0035898"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052","GO:0006810"],"is_obsolete":false,"name":"regulation of parathyroid hormone secretion","synonyms":[{"name":"regulation of PTH secretion","type":"exact"},{"name":"regulation of parathormone secretion","type":"exact"},{"name":"regulation of parathyrin secretion","type":"exact"}],"termid":"GO:2000828"}


id: GO:0072361
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.","definition_xrefs":["GOC:BHF","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter (obsolete GO:0072361)","termid":"GO:0072361"}


id: MONDO:0020521
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Ehlers-Danlos syndrome, arthrochalasia type","termid":"MONDO:0007525"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ehlers-Danlos syndrome type 7A","secondary_identifiers":["icd11.foundation:165998215","UMLS:C3508773","MEDGEN:854083","Orphanet:99875"],"synonyms":[{"name":"EDS VIIA","type":"exact"}],"termid":"MONDO:0020521","xrefs":{"Monarch":{"xref_id":"0020521"}}}


id: PBO:0067921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 223","termid":"PBO:0067921"}


id: PR:O94300
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC887.17 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94300"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"xanthine/uracil permease C887.17 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC887.17","synonyms":[{"name":"Spom972h-SPBC887.17","type":"exact"}],"termid":"PR:O94300"}


id: GO:0097205
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A renal system process in which fluid circulating through the body is filtered through a barrier system.","definition_xrefs":["GOC:pr","GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal system process","termid":"GO:0003014"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"renal filtration","termid":"GO:0097205"}


id: GO:0060109
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals.","definition_xrefs":["GOC:kmv","GOC:dph","ISSN:15518507"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cuticular extracellular matrix","termid":"GO:0060102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"medial layer of collagen and cuticulin-based cuticle extracellular matrix","synonyms":[{"name":"medial layer struts","type":"related"}],"termid":"GO:0060109"}


id: GO:0016984
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 (2R)-3-phosphoglycerate + 2 H+ = CO2 + D-ribulose 1,5-bisphosphate + H2O.","definition_xrefs":["RHEA:23124"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"ribulose-bisphosphate carboxylase activity","secondary_identifiers":["EC:4.1.1.39","MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN"],"synonyms":[{"name":"D-ribulose 1,5-diphosphate carboxylase activity","type":"exact"},{"name":"D-ribulose-1,5-bisphosphate carboxylase activity","type":"exact"},{"name":"RuBP carboxylase activity","type":"exact"},{"name":"RuBisCO activity","type":"exact"},{"name":"carboxydismutase activity","type":"related"},{"name":"diphosphoribulose carboxylase activity","type":"exact"},{"name":"ribulose 1,5-bisphosphate carboxylase activity","type":"exact"},{"name":"ribulose 1,5-bisphosphate carboxylase/oxygenase activity","type":"exact"},{"name":"ribulose 1,5-diphosphate carboxylase activity","type":"exact"},{"name":"ribulose 1,5-diphosphate carboxylase/oxygenase activity","type":"exact"},{"name":"ribulose bisphosphate carboxylase/oxygenase activity","type":"exact"},{"name":"ribulose diphosphate carboxylase activity","type":"exact"},{"name":"ribulose diphosphate carboxylase/oxygenase activity","type":"exact"}],"termid":"GO:0016984"}


id: PBO:0041183
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"butyrophilin like 3","termid":"PBO:0041183"}


id: MONDO:0012439
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Alagille syndrome","termid":"MONDO:0007318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0004335","MONDO:0002515","MONDO:0005267"],"is_obsolete":false,"name":"Alagille syndrome due to a NOTCH2 point mutation","secondary_identifiers":["UMLS:C1857761","GARD:17252","Orphanet:261629","MEDGEN:341844","OMIM:610205"],"synonyms":[{"name":"ALGS2","type":"related"},{"name":"Alagille syndrome 2","type":"related"},{"name":"Alagille syndrome due to a NOTCH2 point mutation","type":"exact"},{"name":"Alagille syndrome type 2","type":"exact"},{"name":"Alagille-Watson syndrome due to a NOTCH2 point mutation","type":"exact"},{"name":"Arteriohepatic dysplasia due to a NOTCH2 point mutation","type":"exact"},{"name":"syndromic bile duct paucity due to a NOTCH2 point mutation","type":"exact"}],"termid":"MONDO:0012439","xrefs":{"Monarch":{"xref_id":"0012439"}}}


