# terms

id: MOD:00235
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-cysteine residue to S-nitrosyl-L-cysteine.","definition_xrefs":["Unimod:275","PubMed:8637569","PubMed:15688001","PubMed:11562475","PubMed:10442087","PubMed:8626764","RESID:AA0230"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"S-nitrosyl-L-cysteine","synonyms":[{"name":"(2R)-2-amino-3-nitrososulfanyl-propanoic acid","type":"exact"},{"name":"L-cysteine nitrite ester","type":"exact"},{"name":"MOD_RES S-nitrosocysteine","type":"exact"},{"name":"Nitrosyl","type":"related"},{"name":"S-nitrosocysteine","type":"exact"},{"name":"S-nitrosyl-L-cysteine","type":"exact"},{"name":"S-nitrosylation","type":"related"},{"name":"SNOCys","type":"exact"}],"termid":"MOD:00235"}


id: MONDO:0018758
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Familial patent arterial duct is a rare, genetic, non-syndromic, congenital anomaly of the great arteries characterized by the presence of an isolated patent arterial duct (PDA) (i.e. failure of closure of ductus arteriosis after birth) in several members of the same family. Clinical presentation is similar to the sporadic form and may range from neonatal-onset tachypnea, diaphoresis and failure to thrive to adult-onset atrial arrhythmia, signs and symptoms of heart failure and cyanosis limited to the lower extremities.","definition_xrefs":["Orphanet:466729"],"gene_count":0,"genotype_count":0,"name":"obsolete familial patent arterial duct (obsolete MONDO:0018758)","termid":"MONDO:0018758","xrefs":{"Monarch":{"xref_id":"0018758"}}}


id: MONDO:0014056
data:
  {"annotated_genes":["SJAG_05979"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86795],"is_not":false,"summary":null,"term":"MONDO:0014056"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"susceptibility to familial cutaneous melanoma","termid":"MONDO:0024462"},{"relation_name":"is_a","term_name":"glioma susceptibility","termid":"MONDO:0100242"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05979":null},"genotype_count":0,"is_obsolete":false,"name":"melanoma, cutaneous malignant, susceptibility to, 9","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:615134","UMLS:C3554574","MEDGEN:767488"],"synonyms":[{"name":"CMM9","type":"related"},{"name":"melanoma, cutaneous malignant, 9","type":"exact"},{"name":"melanoma, cutaneous malignant, susceptibility to, 9","type":"exact"},{"name":"melanoma, cutaneous malignant, susceptibility to, type 9","type":"exact"},{"name":"susceptibility to cutaneous malignant melanoma 9","type":"related"}],"termid":"MONDO:0014056","terms_by_termid":{"MONDO:0014056":null},"xrefs":{"Monarch":{"xref_id":"0014056"}}}


id: PBO:0041725
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium/calmodulin dependent protein kinase II alpha","termid":"PBO:0041725"}


id: PBO:0064261
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pleckstrin homology domain containing A8 pseudogene 1","termid":"PBO:0064261"}


id: PBO:0078333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Glu (anticodon CTC) 1-5","termid":"PBO:0078333"}


id: PBO:0053528
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 525","termid":"PBO:0053528"}


id: FYPO:0002610
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at centromeric outer repeat regions. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H2A phosphorylation during vegetative growth","termid":"FYPO:0002601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0001312","FYPO:0001320"],"is_obsolete":false,"name":"normal histone H2A phosphorylation at centromere outer repeat during vegetative growth","synonyms":[{"name":"abnormal histone H2A phosphorylation at centromere otr during vegetative growth","type":"exact"},{"name":"abnormal histone H2A phosphorylation at centromere outer repeat during vegetative growth","type":"exact"},{"name":"abnormal histone H2A phosphorylation at pericentric region during vegetative growth","type":"related"},{"name":"abnormal histone H2A phosphorylation at pericentromeric region during vegetative growth","type":"related"},{"name":"normal histone H2A phosphorylation at centromere outer repeat during mitotic cell cycle","type":"related"}],"termid":"FYPO:0002610"}


id: GO:0002714
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of lymphocyte mediated immunity","termid":"GO:0002708"},{"relation_name":"is_a","term_name":"regulation of B cell mediated immunity","termid":"GO:0002712"},{"relation_name":"is_a","term_name":"positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","termid":"GO:0002824"},{"relation_name":"positively_regulates","term_name":"B cell mediated immunity","termid":"GO:0019724"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of B cell mediated immunity","synonyms":[{"name":"activation of B cell mediated immunity","type":"narrow"},{"name":"positive regulation of B lymphocyte mediated immunity","type":"exact"},{"name":"positive regulation of B-cell mediated immunity","type":"exact"},{"name":"positive regulation of B-lymphocyte mediated immunity","type":"exact"},{"name":"stimulation of B cell mediated immunity","type":"narrow"},{"name":"up regulation of B cell mediated immunity","type":"exact"},{"name":"up-regulation of B cell mediated immunity","type":"exact"},{"name":"upregulation of B cell mediated immunity","type":"exact"}],"termid":"GO:0002714"}


id: PBO:0071222
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 63","termid":"PBO:0071222"}


id: MONDO:1010907
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Central core myopathy that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central core myopathy, non-human animal","termid":"MONDO:1010192"},{"relation_name":"is_a","term_name":"myofibrillar myopathy, horse","termid":"MONDO:1010936"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"central core myopathy, horse","secondary_identifiers":["OMIA:000172-9796"],"termid":"MONDO:1010907","xrefs":{"Monarch":{"xref_id":"1010907"}}}


id: PBO:0043717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 6B1 pseudogene 5","termid":"PBO:0043717"}


id: GO:1990812
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.","definition_xrefs":["PMID:25598228"],"direct_ancestors":[{"relation_name":"is_a","term_name":"filopodium","termid":"GO:0030175"},{"relation_name":"is_a","term_name":"neuron projection","termid":"GO:0043005"},{"relation_name":"part_of","term_name":"growth cone","termid":"GO:0030426"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"growth cone filopodium","termid":"GO:1990812"}


id: MONDO:0012537
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"tibial aplasia-ectrodactyly syndrome","termid":"MONDO:0018050"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"split-hand/foot malformation with long bone deficiency 2","secondary_identifiers":["UMLS:C1853156","GARD:15492","OMIM:610685","MESH:C565199","MEDGEN:377841"],"synonyms":[{"name":"SHFLD2","type":"exact"},{"name":"split-hand/foot malformation with long bone deficiency 2","type":"exact"}],"termid":"MONDO:0012537","xrefs":{"Monarch":{"xref_id":"0012537"}}}


id: PR:O13622
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mss116 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13622"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase mss116, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC691.04","synonyms":[{"name":"Spom972h-mss116","type":"exact"}],"termid":"PR:O13622"}


id: GO:0102473
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose = 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity (obsolete GO:0102473)","termid":"GO:0102473"}


id: GO:0102009
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal = L-proline + a standard alpha amino acid.","definition_xrefs":["EC:3.4.13.9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dipeptidase activity","termid":"GO:0016805"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0008233"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0140096","GO:0008233","GO:0003824"],"is_obsolete":false,"name":"proline dipeptidase activity","secondary_identifiers":["MetaCyc:3.4.13.9-RXN","RHEA:76407"],"termid":"GO:0102009"}


id: MONDO:0006274
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An intraepithelial lesion of the vulvar squamous epithelium that represents the clinical and morphological manifestation of a productive HPV infection. Low grade refers to the associated low risk of concurrent or future cancer. (WHO, 2014)","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vulvar intraepithelial neoplasia","termid":"MONDO:0005198"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"low grade vulvar intraepithelial neoplasia","secondary_identifiers":["MEDGEN:99217","EFO:1000330","NCIT:C4760","UMLS:C0495106"],"synonyms":[{"name":"VIN 1","type":"exact"},{"name":"VIN 1 of usual type","type":"exact"},{"name":"VIN grade 1","type":"exact"},{"name":"grade 1 VIN","type":"exact"},{"name":"grade 1 vulvar intraepithelial neoplasia","type":"exact"},{"name":"grade I VIN","type":"exact"},{"name":"grade I vulvar intraepithelial neoplasia","type":"exact"},{"name":"intraepithelial neoplasia of the vulva grade 1","type":"exact"},{"name":"intraepithelial neoplasia of vulva grade 1","type":"exact"},{"name":"low grade VIN","type":"exact"},{"name":"vulva intraepithelial neoplasia grade 1","type":"exact"},{"name":"vulvar Low grade squamous intraepithelial lesion","type":"exact"},{"name":"vulvar Low-grade squamous intraepithelial lesion","type":"exact"},{"name":"vulvar flat condyloma","type":"exact"},{"name":"vulvar intraepithelial neoplasia 1 of usual type","type":"exact"},{"name":"vulvar intraepithelial neoplasia grade 1","type":"exact"},{"name":"vulvar mild squamous dysplasia","type":"exact"}],"termid":"MONDO:0006274","xrefs":{"Monarch":{"xref_id":"0006274"}}}


id: MONDO:0012580
data:
  {"annotated_genes":["SJAG_01159"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85369],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014206"}]},"cv_name":"mondo","definition":"Congenital pulmonary alveolar proteinosis is a very rare primary interstitial lung disease due to pulmonary surfactant accumulation within the alveolar macrophages and alveoli, characterized by a variable clinical course ranging from an asymptomatic clinical presentation and spontaneous remission, to symptoms such as dyspnea and cough, or to severe respiratory failure.","definition_xrefs":["Orphanet:264675"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pulmonary alveolar proteinosis","termid":"MONDO:0001437"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01159":null},"genotype_count":0,"is_obsolete":false,"name":"hereditary pulmonary alveolar proteinosis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:C535832","NANDO:2200200","GARD:4582","SCTID:707442002","NANDO:1200750","OMIMPS:265120","UMLS:C3711368","MEDGEN:777976","NANDO:1200746"],"synonyms":[{"name":"congenital PAP","type":"exact"},{"name":"congenital pulmonary alveolar proteinosis","type":"exact"},{"name":"hereditary pulmonary alveolar proteinosis","type":"exact"},{"name":"inborn error of pulmonary surfactant metabolism","type":"exact"},{"name":"inborn error of surfactant metabolism","type":"exact"},{"name":"pulmonary alveolar proteinosis, congenital","type":"related"},{"name":"sufactant metabolism dysfunction, pulmonary","type":"related"}],"termid":"MONDO:0012580","terms_by_termid":{"MONDO:0014206":null},"xrefs":{"Monarch":{"xref_id":"0012580"}}}


id: FYPO:0003412
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromatin silencing at centromere outer repeat","termid":"FYPO:0002346"},{"relation_name":"is_a","term_name":"decreased chromatin silencing at centromere","termid":"FYPO:0002834"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0006551","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"decreased chromatin silencing at centromere outer repeat","synonyms":[{"name":"decreased chromatin silencing at centromere otr","type":"exact"},{"name":"decreased chromatin silencing at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"decreased chromatin silencing at centromere outer repeat during vegetative growth","type":"exact"},{"name":"decreased chromatin silencing at centromere outer repeat region","type":"exact"},{"name":"decreased chromatin silencing at centromeric outer repeat region","type":"exact"},{"name":"decreased chromatin silencing at pericentric region","type":"related"},{"name":"decreased chromatin silencing at pericentromeric region","type":"related"},{"name":"decreased heterochromatin silencing at centromere outer repeat region","type":"exact"},{"name":"reduced chromatin silencing at centromere outer repeat","type":"exact"}],"termid":"FYPO:0003412"}


id: GO:0097017
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).","definition_xrefs":["PMID:18431508","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal absorption","termid":"GO:0070293"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"renal protein absorption","termid":"GO:0097017"}


id: PBO:0088028
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 snoRNP protein; component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA","termid":"PBO:0088028"}


id: MONDO:0044652
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete optic atrophy-peripheral neuropathy-developmental delay syndrome (obsolete MONDO:0044652)","termid":"MONDO:0044652","xrefs":{"Monarch":{"xref_id":"0044652"}}}


id: MONDO:0800438
data:
  {"annotated_genes":["SJAG_01058"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85126],"is_not":false,"summary":null,"term":"MONDO:0800438"}]},"cv_name":"mondo","definition":"Any developmental delay with short stature, dysmorphic facial features, and sparse hair in which the cause of the disease is a mutation in the DPH1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"excluded_subClassOf","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"excluded_subClassOf","term_name":"obsolete dysostosis of genetic origin (obsolete MONDO:0018454)","termid":"MONDO:0018454"},{"relation_name":"is_a","term_name":"developmental delay with short stature, dysmorphic facial features, and sparse hair","termid":"MONDO:0031632"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01058":null},"genotype_count":0,"is_obsolete":false,"name":"developmental delay with short stature, dysmorphic facial features, and sparse hair 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:459061","GARD:17814","OMIM:616901","DOID:0070477"],"synonyms":[{"name":"DEDSSH1","type":"exact"},{"name":"Loucks-Innes syndrome","type":"related"},{"name":"developmental delay with short stature, dysmorphic facial features, and sparse hair","type":"broad"},{"name":"developmental delay with short stature, dysmorphic features, and sparse hair 1","type":"exact"},{"name":"developmental delay-short stature-dysmorphic features-sparse hair syndrome","type":"broad"},{"name":"diphtamide deficiency syndrome","type":"exact"}],"termid":"MONDO:0800438","terms_by_termid":{"MONDO:0800438":null},"xrefs":{"Monarch":{"xref_id":"0800438"}}}


id: RO:0002640
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A sub-relation of endoparasite-of in which the parasite inhabits host cells.","direct_ancestors":[{"relation_name":"is_a","term_name":"endoparasite_of","termid":"RO:0002634"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intracellular_endoparasite_of","termid":"RO:0002640"}


id: MONDO:0002229
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, borderline, or malignant tumor that originates from the surface epithelium of the ovary. It is composed of epithelial cells and stroma. Representative examples of benign tumors include serous cystadenoma, mucinous cystadenoma, and benign Brenner tumor. Representative examples of borderline tumors include serous surface papillary tumor, mucinous adenofibroma, and borderline Brenner tumor. Representative examples of malignant tumors include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, and malignant Brenner tumor.","definition_xrefs":["NCIT:C4381"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial neoplasm","termid":"MONDO:0005626"},{"relation_name":"is_a","term_name":"ovarian neoplasm","termid":"MONDO:0021068"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovarian epithelial tumor","secondary_identifiers":["MEDGEN:90969","DOID:2152","ICD9:239.5","ONCOTREE:OVT","SCTID:237057005","UMLS:C0341823"],"synonyms":[{"name":"OVT","type":"related"},{"name":"epithelial neoplasm of ovary","type":"exact"},{"name":"epithelial neoplasm of the ovary","type":"exact"},{"name":"epithelial tumor of ovary","type":"exact"},{"name":"epithelial tumor of the ovary","type":"exact"},{"name":"epithelial tumour of ovary","type":"exact"},{"name":"epithelial tumour of the ovary","type":"exact"},{"name":"ovarian epithelial tumor","type":"exact"},{"name":"ovarian surface epithelial-stromal tumor","type":"exact"},{"name":"ovarian surface epithelial-stromal tumour","type":"exact"},{"name":"ovarian surface-epithelial stromal neoplasm","type":"exact"},{"name":"ovary epithelial cancer","type":"related"},{"name":"ovary epithelial neoplasm","type":"exact"}],"termid":"MONDO:0002229","xrefs":{"Monarch":{"xref_id":"0002229"}}}


id: PBO:0055211
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2636","termid":"PBO:0055211"}


id: PBO:0002774
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vigtamin H transporter (predicted)","termid":"PBO:0002774"}


id: PBO:0006981
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Negative Regulator of Condensin","termid":"PBO:0006981"}


id: PBO:0070628
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7 like 1 pseudogene 12","termid":"PBO:0070628"}


id: MOD:00394
data:
  {"annotated_genes":["SJAG_02522","SJAG_00733"],"annotation_feature_type":"gene","cv_annotations":{"PSI-MOD":[{"annotations":[80290,80001],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00050"}]},"cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom with an acetyl group.","definition_xrefs":["PubMed:14730666","PubMed:12175151","PubMed:11999733","DeltaMass:0","PubMed:11857757","PubMed:15350136","Unimod:1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acylated residue","termid":"MOD:00649"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00733":null,"SJAG_02522":null},"genotype_count":0,"is_obsolete":false,"name":"acetylated residue","references_by_uniquename":{"PMID:36408920":null},"synonyms":[{"name":"AcRes","type":"exact"},{"name":"Acetyl","type":"related"},{"name":"Acetylation","type":"related"},{"name":"Acetylation (N terminus, N epsilon of Lysine, O of Serine) (Ac)","type":"exact"}],"termid":"MOD:00394","terms_by_termid":{"MOD:00050":null}}


id: PR:P22192
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pac1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P22192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"double-strand-specific pac1 ribonuclease (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC119.11c","synonyms":[{"name":"Spom972h-pac1","type":"exact"},{"name":"protein hcs (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P22192"}


id: GO:0071162
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.","definition_xrefs":["PMID:19228417","GOC:rb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA replication preinitiation complex","termid":"GO:0031261"},{"relation_name":"part_of","term_name":"nuclear chromosome","termid":"GO:0000228"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"part_of","termid":"GO:0005654"}],"interesting_parent_ids":["GO:0032991","GO:0005634","GO:0005694","GO:0005654","GO:0005575"],"is_obsolete":false,"name":"CMG complex","synonyms":[{"name":"unwindosome","type":"exact"}],"termid":"GO:0071162"}


id: PBO:0090361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-protein ligase E3, unknown specificity","termid":"PBO:0090361"}


id: PBO:0072509
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein SA pseudogene 38","termid":"PBO:0072509"}


id: PBO:0049738
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hemoglobin subunit beta","termid":"PBO:0049738"}


id: GO:1903249
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.","definition_xrefs":["GOC:BHF","GO_REF:0000058","PMID:19278978","GOC:TermGenie","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of small molecule metabolic process","termid":"GO:0062014"},{"relation_name":"is_a","term_name":"regulation of citrulline biosynthetic process","termid":"GO:1903248"},{"relation_name":"is_a","term_name":"negative regulation of amino acid biosynthetic process","termid":"GO:2000283"},{"relation_name":"negatively_regulates","term_name":"citrulline biosynthetic process","termid":"GO:0019240"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006520"},{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0006520","GO:0044281"],"is_obsolete":false,"name":"negative regulation of citrulline biosynthetic process","synonyms":[{"name":"down regulation of citrulline anabolism","type":"exact"},{"name":"down regulation of citrulline biosynthesis","type":"exact"},{"name":"down regulation of citrulline biosynthetic process","type":"exact"},{"name":"down regulation of citrulline formation","type":"exact"},{"name":"down regulation of citrulline synthesis","type":"exact"},{"name":"down-regulation of citrulline anabolism","type":"exact"},{"name":"down-regulation of citrulline biosynthesis","type":"exact"},{"name":"down-regulation of citrulline biosynthetic process","type":"exact"},{"name":"down-regulation of citrulline formation","type":"exact"},{"name":"down-regulation of citrulline synthesis","type":"exact"},{"name":"downregulation of citrulline anabolism","type":"exact"},{"name":"downregulation of citrulline biosynthesis","type":"exact"},{"name":"downregulation of citrulline biosynthetic process","type":"exact"},{"name":"downregulation of citrulline formation","type":"exact"},{"name":"downregulation of citrulline synthesis","type":"exact"},{"name":"inhibition of citrulline anabolism","type":"narrow"},{"name":"inhibition of citrulline biosynthesis","type":"narrow"},{"name":"inhibition of citrulline biosynthetic process","type":"narrow"},{"name":"inhibition of citrulline formation","type":"narrow"},{"name":"inhibition of citrulline synthesis","type":"narrow"},{"name":"negative regulation of citrulline anabolism","type":"exact"},{"name":"negative regulation of citrulline biosynthesis","type":"exact"},{"name":"negative regulation of citrulline formation","type":"exact"},{"name":"negative regulation of citrulline synthesis","type":"exact"}],"termid":"GO:1903249"}


id: MONDO:0024382
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A circadian sleep disorder that occurs when work schedules force people to be awake when their circadian rhythms dictate that they should be sleeping. It is classified as a Circadian Rhythm Disorder (CRD) and is extrinsic, i.e. caused by external behavioral factors.","direct_ancestors":[{"relation_name":"is_a","term_name":"circadian rhythm sleep disorder","termid":"MONDO:0024361"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"circadian rhythm sleep disorder, shift work type","secondary_identifiers":["ICD10CM:G47.26","UMLS:C0393773","MEDGEN:501114","SCTID:713498009"],"synonyms":[{"name":"circadian rhythm sleep disorder of shift work type","type":"exact"},{"name":"shift work disorder","type":"exact"}],"termid":"MONDO:0024382","xrefs":{"Monarch":{"xref_id":"0024382"}}}


id: PBO:0003651
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"random septum position protein Rsp1","termid":"PBO:0003651"}


id: MOD:00734
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with an N-acetylgalactosamine group through a glycosidic bond.","definition_xrefs":["DeltaMass:247"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acetylhexosaminylated residue","termid":"MOD:00436"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"N-acetylaminogalactosylated","synonyms":[{"name":"GalNAc","type":"exact"},{"name":"N-acetylhexosamines (GalNAc, GlcNAc)","type":"exact"}],"termid":"MOD:00734"}


id: GO:0000433
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon catabolite repression of transcription by glucose","termid":"GO:0045014"},{"relation_name":"is_a","term_name":"negative regulation of transcription from RNA polymerase II promoter by glucose","termid":"GO:0061987"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"negatively_regulates","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0006351","GO:0006355","GO:0008150"],"is_obsolete":false,"name":"carbon catabolite repression of transcription from RNA polymerase II promoter by glucose","synonyms":[{"name":"down regulation of transcription from RNA polymerase II promoter by glucose","type":"exact"},{"name":"down-regulation of transcription from RNA polymerase II promoter by glucose","type":"exact"},{"name":"downregulation of transcription from RNA polymerase II promoter by glucose","type":"exact"},{"name":"inhibition of transcription from RNA polymerase II promoter by glucose","type":"narrow"}],"termid":"GO:0000433"}


id: PBO:0091204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Leu","termid":"PBO:0091204"}


id: PBO:0041281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C1q and TNF related 7","termid":"PBO:0041281"}


id: GO:0031345
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell projection organization","termid":"GO:0031344"},{"relation_name":"is_a","term_name":"negative regulation of cellular component organization","termid":"GO:0051129"},{"relation_name":"negatively_regulates","term_name":"cell projection organization","termid":"GO:0030030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell projection organization","synonyms":[{"name":"down regulation of cell projection organization","type":"exact"},{"name":"down-regulation of cell projection organization","type":"exact"},{"name":"downregulation of cell projection organization","type":"exact"},{"name":"inhibition of cell projection organization","type":"narrow"},{"name":"negative regulation of cell projection organisation","type":"exact"},{"name":"negative regulation of cell projection organization and biogenesis","type":"related"}],"termid":"GO:0031345"}


id: GO:0002035
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.","definition_xrefs":["PMID:2909574"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system process involved in regulation of systemic arterial blood pressure","termid":"GO:0001976"},{"relation_name":"is_a","term_name":"regulation of blood volume by renin-angiotensin","termid":"GO:0002016"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"brain renin-angiotensin system","termid":"GO:0002035"}


id: GO:0032221
data:
  {"annotated_genes":["SJAG_01804","SJAG_00581","SJAG_03884","SJAG_00349","SJAG_04758","SJAG_01110"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[89306,93279,93811,94949,95388,108924],"is_not":false,"summary":null,"term":"GO:0032221"}]},"cv_name":"cellular_component","definition":"A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).","definition_xrefs":["PMID:17450151","GOC:vw","PMID:12773392"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Sin3-type complex","termid":"GO:0070822"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00349":null,"SJAG_00581":null,"SJAG_01110":null,"SJAG_01804":null,"SJAG_03884":null,"SJAG_04758":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005654"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575","GO:0005654","GO:0005694"],"is_obsolete":false,"name":"Rpd3S complex","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0000509"],"synonyms":[{"name":"Clr6 histone deacetylase complex II","type":"exact"},{"name":"Clr6 histone deacetylase complex II'","type":"exact"},{"name":"Clr6-CII complex","type":"exact"},{"name":"Clr6S complex","type":"exact"},{"name":"Rpd3C(S)","type":"exact"},{"name":"Rpd3S","type":"exact"},{"name":"Sin3S","type":"exact"}],"termid":"GO:0032221","terms_by_termid":{"GO:0032221":null}}


id: PBO:0087288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells","termid":"PBO:0087288"}


id: FYPO:0001159
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vegetative cell phenotype","termid":"FYPO:0003755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular pH","synonyms":[{"name":"increased cellular pH during mitotic cell cycle","type":"related"},{"name":"increased cellular pH during vegetative growth","type":"exact"},{"name":"increased cellular pH level","type":"exact"}],"termid":"FYPO:0001159"}


id: PBO:0047568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibroblast growth factor 19","termid":"PBO:0047568"}


id: PATO:0002007
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave.","definition_xrefs":["PATOC:CJM"],"direct_ancestors":[{"relation_name":"has_cross_section","term_name":"2-D shape","termid":"PATO:0002006"},{"relation_name":"is_a","term_name":"3-D shape","termid":"PATO:0002266"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"convex 3-D shape","secondary_identifiers":["Image:http\\://upload.wikimedia.org/wikipedia/commons/0/06/Convex_polygon_illustration1.png"],"termid":"PATO:0002007"}


id: RO:0002209
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"inverse of parasitoid of","direct_ancestors":[{"relation_name":"is_a","term_name":"parasitized_by","termid":"RO:0002445"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_parasitoid","termid":"RO:0002209"}


id: PBO:0000995
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5'-methylthioribulose-1-phosphate dehydratase, adducin (predicted)","termid":"PBO:0000995"}


id: MONDO:0010912
data:
  {"annotated_genes":["SJAG_04003"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86294],"is_not":false,"summary":null,"term":"MONDO:0010912"}]},"cv_name":"mondo","definition":"Any congenital fibrosis of extraocular muscles in which the cause of the disease is a mutation in the TUBB3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital fibrosis of extraocular muscles","termid":"MONDO:0007614"},{"relation_name":"is_a","term_name":"TUBB3-related tubulinopathy","termid":"MONDO:0100154"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04003":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"fibrosis of extraocular muscles, congenital, 3A, with or without extraocular involvement","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:412638","GARD:15321","OMIM:600638","MESH:C567572","UMLS:C2748801","DOID:0081017"],"synonyms":[{"name":"CFEOM3A","type":"related"},{"name":"Feom3 locus","type":"related"},{"name":"TUBB3 congenital fibrosis of extraocular muscles","type":"exact"},{"name":"congenital fibrosis of extraocular muscles caused by mutation in TUBB3","type":"exact"},{"name":"fibrosis of extraocular muscles, congenital, 3A","type":"exact"},{"name":"fibrosis of extraocular muscles, congenital, 3A, with or without extraocular involvement","type":"exact"}],"termid":"MONDO:0010912","terms_by_termid":{"MONDO:0010912":null},"xrefs":{"Monarch":{"xref_id":"0010912"}}}


id: MONDO:0021476
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the tongue.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory organ benign neoplasm","termid":"MONDO:0000633"},{"relation_name":"is_a","term_name":"tongue neoplasm","termid":"MONDO:0021240"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign neoplasm of tongue","secondary_identifiers":["ICD9:210.1","NCIT:C3592","UMLS:C0153933","icd11.foundation:487744161","SCTID:92443005","ICD10CM:D10.1","MEDGEN:57573"],"synonyms":[{"name":"benign neoplasm of the tongue","type":"exact"},{"name":"benign tongue neoplasm","type":"exact"},{"name":"benign tongue tumor","type":"exact"},{"name":"benign tongue tumour","type":"exact"},{"name":"benign tumor of the tongue","type":"exact"},{"name":"benign tumor of tongue","type":"exact"},{"name":"benign tumour of the tongue","type":"exact"},{"name":"benign tumour of tongue","type":"exact"},{"name":"tongue benign neoplasm","type":"exact"},{"name":"tongue neoplasm, benign","type":"exact"}],"termid":"MONDO:0021476","xrefs":{"Monarch":{"xref_id":"0021476"}}}


id: PBO:0074195
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 39 member 5","termid":"PBO:0074195"}


id: PBO:0061029
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ninein","termid":"PBO:0061029"}


id: PBO:0060247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MYCBP2 antisense RNA 2","termid":"PBO:0060247"}


id: GO:0033379
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.","definition_xrefs":["GOC:tb","GOC:dph","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maintenance of protein location in T cell secretory granule","termid":"GO:0033377"},{"relation_name":"part_of","term_name":"protease localization to T cell secretory granule","termid":"GO:0033375"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"maintenance of protease location in T cell secretory granule","synonyms":[{"name":"maintenance of protease localization in T cell secretory granule","type":"related"},{"name":"maintenance of protease localization in T lymphocyte secretory granule","type":"exact"},{"name":"maintenance of protease localization in T-cell secretory granule","type":"exact"},{"name":"maintenance of protease localization in T-lymphocyte secretory granule","type":"exact"}],"termid":"GO:0033379"}


id: PBO:0000184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycine cleavage complex subunit P (predicted)","termid":"PBO:0000184"}


id: PBO:0028841
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-heterochromatin_assembly_beyond_boundary_element_IRC3L","termid":"PBO:0028841"}


id: PBO:0083248
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry","termid":"PBO:0083248"}


id: GO:0072427
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to an intra-S DNA damage checkpoint.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete detection of DNA damage stimulus involved in intra-S DNA damage checkpoint (obsolete GO:0072427)","synonyms":[{"name":"intra-S DNA damage checkpoint sensor mechanism","type":"related"},{"name":"intra-S DNA damage checkpoint sensor process","type":"related"},{"name":"sensing involved in intra-S DNA damage checkpoint","type":"related"}],"termid":"GO:0072427"}


id: GO:0052838
data:
  {"annotated_genes":["SJAG_00827"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[106844],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052837"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfur compound metabolic process","termid":"GO:0006790"},{"relation_name":"is_a","term_name":"oxazole or thiazole metabolic process","termid":"GO:0046484"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00827":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006790"}],"interesting_parent_ids":["GO:0008150","GO:0006790"],"is_obsolete":false,"name":"thiazole metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"thiazole metabolism","type":"exact"}],"termid":"GO:0052838","terms_by_termid":{"GO:0052837":null}}


id: MOD:01718
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with a Proteome Sciences TMT6plex reporter+balance group.","definition_xrefs":["Unimod:214#N-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isotope tagged reagent alpha-amino acylated residue","termid":"MOD:01708"},{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent N-acylated residue","termid":"MOD:01717"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex reporter+balance reagent acylated N-terminal","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01718"}


id: PBO:0089666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent chromatin remodeller/ubiquitin-protein ligase E3 Rad8","termid":"PBO:0089666"}


id: PBO:0056453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methionyl-tRNA synthetase 1","termid":"PBO:0056453"}


id: FYPO:0004961
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is increased.","definition_xrefs":["PMID:12419251","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein localization to chromatin during vegetative growth","termid":"FYPO:0003011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"increased protein localization to chromatin at replication origin","synonyms":[{"name":"increased protein localisation to chromatin at replication origin","type":"exact"},{"name":"increased protein localization to chromatin at replication origins during mitotic cell cycle","type":"related"},{"name":"increased protein localization to chromatin at replication origins during vegetative growth","type":"exact"}],"termid":"FYPO:0004961"}


id: MONDO:0019425
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete X-linked intellectual disability-hypotonia-facial dysmorphism-aggressive behavior syndrome (obsolete MONDO:0019425)","termid":"MONDO:0019425","xrefs":{"Monarch":{"xref_id":"0019425"}}}


id: GO:0004833
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.","definition_xrefs":["EC:1.13.11.11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","termid":"GO:0016702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"tryptophan 2,3-dioxygenase activity","secondary_identifiers":["Reactome:R-HSA-71188","Reactome:R-HSA-888614","GO:0004426","MetaCyc:TRYPTOPHAN-23-DIOXYGENASE-RXN","RHEA:24536","Reactome:R-HSA-198563"],"synonyms":[{"name":"L-tryptophan 2,3-dioxygenase activity","type":"related"},{"name":"L-tryptophan pyrrolase activity","type":"related"},{"name":"L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)","type":"related"},{"name":"TDO","type":"related"},{"name":"indolamine 2,3-dioxygenase activity","type":"broad"},{"name":"indoleamine-pyrrole 2,3-dioxygenase activity","type":"exact"},{"name":"tryptamin 2,3-dioxygenase activity","type":"related"},{"name":"tryptamine 2,3-dioxygenase activity","type":"related"},{"name":"tryptophan oxygenase activity","type":"broad"},{"name":"tryptophan peroxidase activity","type":"broad"},{"name":"tryptophan pyrrolase activity","type":"broad"}],"termid":"GO:0004833"}


id: PBO:0078388
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Phe (anticodon GAA) 1-3","termid":"PBO:0078388"}


id: MONDO:0013768
data:
  {"annotated_genes":["SJAG_05213","SJAG_03785","SJAG_01344"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86180,86181,86182],"is_not":false,"summary":null,"term":"MONDO:0013768"}]},"cv_name":"mondo","definition":"Any arterial calcification of infancy in which the cause of the disease is a mutation in the ABCC6 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"oculocutaneous albinism","termid":"MONDO:0018910"},{"relation_name":"is_a","term_name":"arterial calcification of infancy","termid":"MONDO:0018870"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01344":null,"SJAG_03785":null,"SJAG_05213":null},"genotype_count":0,"is_obsolete":false,"name":"arterial calcification, generalized, of infancy, 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:477791","UMLS:C3276161","OMIM:614473"],"synonyms":[{"name":"ABCC6 arterial calcification of infancy","type":"exact"},{"name":"GACI2","type":"related"},{"name":"arterial calcification of infancy caused by mutation in ABCC6","type":"exact"},{"name":"arterial calcification, generalized, of infancy, 2","type":"exact"},{"name":"arterial calcification, generalized, of infancy, type 2","type":"exact"}],"termid":"MONDO:0013768","terms_by_termid":{"MONDO:0013768":null},"xrefs":{"Monarch":{"xref_id":"0013768"}}}


id: PBO:0070348
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY4 pseudogene 21","termid":"PBO:0070348"}


id: FYPO:0006017
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing urea.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0002058","FYPO:0002060","FYPO:0000139","FYPO:0000003","FYPO:0000257"],"is_obsolete":false,"name":"normal growth on urea","synonyms":[{"name":"normal cell population growth in presence of urea","type":"exact"},{"name":"normal cell population growth on urea","type":"exact"},{"name":"normal vegetative cell population growth on urea","type":"exact"}],"termid":"FYPO:0006017"}


id: GO:0045281
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones.","definition_xrefs":["GOC:kd","InterPro:IPR000701"],"gene_count":0,"genotype_count":0,"name":"obsolete succinate dehydrogenase complex (obsolete GO:0045281)","termid":"GO:0045281"}


id: MONDO:0003896
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A capillary hemangioma arising from the breast.","definition_xrefs":["NCIT:C5210"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"breast angiomatosis","termid":"MONDO:0002064"},{"relation_name":"is_a","term_name":"capillary hemangioma","termid":"MONDO:0002407"},{"relation_name":"is_a","term_name":"breast hemangioma","termid":"MONDO:0003126"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"breast capillary hemangioma","secondary_identifiers":["DOID:6491","UMLS:C1332619","MEDGEN:231963"],"synonyms":[{"name":"breast capillary angioma","type":"exact"},{"name":"breast capillary hemangioma","type":"exact"},{"name":"capillary angioma of breast","type":"exact"},{"name":"capillary angioma of the breast","type":"exact"},{"name":"capillary hemangioma of breast","type":"exact"},{"name":"capillary hemangioma of the breast","type":"exact"}],"termid":"MONDO:0003896","xrefs":{"Monarch":{"xref_id":"0003896"}}}


id: PBO:0050615
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydroxysteroid 17-beta dehydrogenase 7 pseudogene 1","termid":"PBO:0050615"}


id: PBO:0040449
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase phospholipid transporting 10B (putative)","termid":"PBO:0040449"}


id: PBO:0050018
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"major histocompatibility complex, class II, DO alpha","termid":"PBO:0050018"}


id: GO:0031361
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.","definition_xrefs":["GOC:dos","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete integral component of thylakoid membrane (obsolete GO:0031361)","synonyms":[{"name":"integral to thylakoid membrane","type":"narrow"}],"termid":"GO:0031361"}


id: MONDO:1012933
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cleft palate that occurs in chickens due to a mutation in the ESRP2 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cleft palate, chicken","termid":"MONDO:1010525"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cleft primary palate, ESRP2-related, chicken","secondary_identifiers":["OMIA:002543-9031"],"termid":"MONDO:1012933","xrefs":{"Monarch":{"xref_id":"1012933"}}}


id: GO:0005260
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.","definition_xrefs":["PMID:24727426","PMID:9922375"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chloride channel activity","termid":"GO:0005254"},{"relation_name":"is_a","term_name":"ligand-gated monoatomic anion channel activity","termid":"GO:0099095"},{"relation_name":"is_a","term_name":"intracellularly ATP-gated ion channel activity","termid":"GO:0099142"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"intracellularly ATP-gated chloride channel activity","secondary_identifiers":["GO:0005224","TC:3.A.1.202.1","EC:5.6.1.6","Wikipedia:Cystic_fibrosis_transmembrane_conductance_regulator","MetaCyc:3.6.3.49-RXN"],"synonyms":[{"name":"CFTR","type":"exact"},{"name":"channel-conductance-controlling ATPase activity","type":"related"},{"name":"cystic fibrosis transmembrane conductance regulator","type":"narrow"}],"termid":"GO:0005260"}


id: PBO:0029751
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_modification","termid":"PBO:0029751"}


id: PBO:0088128
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar membrane protein involved in termination of autophagy; regulates autophagy termination during persistent nitrogen starvation through Atg1p-mediated re-phosphorylation of Atg13p and PAS disassembly; type II membrane protein containing a hydrophobic transmembrane region, with N-terminal region oriented toward the cytosol and C-terminus inside the lumen; luminal domain is glycosylated; forms foci in the vacuole membrane during starvation","termid":"PBO:0088128"}


id: GO:0009902
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.","definition_xrefs":["PMID:11309623"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chloroplast organization","termid":"GO:0009658"},{"relation_name":"is_a","term_name":"chloroplast localization","termid":"GO:0019750"},{"relation_name":"is_a","term_name":"establishment of plastid localization","termid":"GO:0051667"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"chloroplast relocation","synonyms":[{"name":"chloroplast movement","type":"exact"}],"termid":"GO:0009902"}


id: PBO:0031086
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-translation_regulation_phenotype","termid":"PBO:0031086"}


id: PBO:0075258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 18 pseudogene 11","termid":"PBO:0075258"}


id: PBO:0016076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Hal4","termid":"PBO:0016076"}


id: PBO:0030422
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_sterol_binding","termid":"PBO:0030422"}


id: PBO:0003621
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar membrane palmitoyltransferase Pfa5 (predicted)","termid":"PBO:0003621"}


id: PBO:0053691
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 886","termid":"PBO:0053691"}


id: GO:0141080
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont subverts an interferon-mediated signal transduction pathway in the host organism by initiating, promoting, or enhancing its activation.","definition_xrefs":["PMID:26553469","PMID:29076073"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated activation of host signal transduction pathway","termid":"GO:0052028"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated activation of host interferon signaling pathway","termid":"GO:0141080"}


id: FYPO:0007220
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in regions containing protein-coding genes is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:31260531","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H3-K9 acetylation during vegetative growth","termid":"FYPO:0003223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal histone H3-K9 acetylation at protein coding gene during vegetative growth","synonyms":[{"name":"normal histone H3-K9 acetylation at protein coding gene during mitotic cell cycle","type":"related"},{"name":"normal histone H3-K9 acetylation at protein-coding gene during vegetative growth","type":"exact"},{"name":"normal histone H3K9 acetylation at protein coding gene during vegetative growth","type":"exact"}],"termid":"FYPO:0007220"}


id: MOD:01066
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a hydrogen atom of an L-phenylalanine residue with a halogen atom.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"halogen containing residue","termid":"MOD:00694"},{"relation_name":"is_a","term_name":"modified L-phenylalanine residue","termid":"MOD:00914"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"halogenated phenylalanine","synonyms":[{"name":"HalPhe","type":"exact"}],"termid":"MOD:01066"}


id: GO:0021918
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis.","definition_xrefs":["PMID:11262869","GOC:dgh","GOC:jid","GO_REF:0000021","GOC:cls","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment (obsolete GO:0021918)","termid":"GO:0021918"}


id: MONDO:0006523
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inflammatory skin condition affecting children. It is often associated with Epstein-Barr virus infection, hepatitis B infection or cytomegalovirus infection. It is characterized by the presence of cutaneous rashes and patches on the palms and soles. The trunk is not affected.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dermatitis","termid":"MONDO:0002406"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"acrodermatitis","secondary_identifiers":["ICD9:686.8","SCTID:8197001","UMLS:C0001197","CSP:4008-0032","MESH:D000169","EFO:1000664","NCIT:C84532","DOID:2722","MEDGEN:1301"],"termid":"MONDO:0006523","xrefs":{"Monarch":{"xref_id":"0006523"}}}


id: PBO:0066061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rap guanine nucleotide exchange factor 5","termid":"PBO:0066061"}


id: PBO:0028274
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-cytoplasmic_vesicles_present_in_increased_numbers","termid":"PBO:0028274"}


id: PBO:0088266
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fatty acid desaturase domain protein","termid":"PBO:0088266"}


id: PBO:0040885
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bone morphogenetic protein 8a","termid":"PBO:0040885"}


id: MONDO:0016516
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A genetic condition characterized by long bone sclerosis and thickening, short stature, and head and eye anomalies. Many affected individuals have hypoparathyroidism with hypocalcemia.","definition_xrefs":["NCIT:C130991"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"primordial dwarfism and slender bone disorder","termid":"MONDO:0800063"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kenny-Caffey syndrome","secondary_identifiers":["MESH:C537020","DOID:0080724","SCTID:82837002","GARD:16594","OMIMPS:127000","ICD9:759.89","NORD:1325","MEDGEN:75560","UMLS:C0265291","Orphanet:2333"],"synonyms":[{"name":"Kenny syndrome","type":"exact"}],"termid":"MONDO:0016516","xrefs":{"Monarch":{"xref_id":"0016516"}}}


id: MONDO:0011253
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Craniomicromelic syndrome is a very rare disorder characterized by intrauterine growth retardation, underossification of the skull with large fontanels, short limbs with absent phalanges and finger and toe syndactyly.","definition_xrefs":["Orphanet:1524"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic craniosynostosis","termid":"MONDO:0015338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"craniomicromelic syndrome","secondary_identifiers":["OMIM:602558","MESH:C566522","MEDGEN:355396","SCTID:725098001","UMLS:C1865184","GARD:1583","icd11.foundation:1734157428"],"synonyms":[{"name":"craniomicromelic syndrome","type":"exact"}],"termid":"MONDO:0011253","xrefs":{"Monarch":{"xref_id":"0011253"}}}


id: GO:0010219
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.","definition_xrefs":["GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to stress","termid":"GO:0080134"},{"relation_name":"regulates","term_name":"vernalization response","termid":"GO:0010048"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of vernalization response","termid":"GO:0010219"}


id: MONDO:1012041
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cerebellar abiotrophy, non-human animal","termid":"MONDO:1011834"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebellar abiotrophy, cattle","secondary_identifiers":["OMIA:000175-9913"],"termid":"MONDO:1012041","xrefs":{"Monarch":{"xref_id":"1012041"}}}


id: GO:0005165
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a neurotrophin receptor.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine receptor binding","termid":"GO:0005126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"neurotrophin receptor binding","synonyms":[{"name":"neurotrophin","type":"narrow"},{"name":"neurotrophin receptor ligand","type":"narrow"}],"termid":"GO:0005165"}


id: GO:0018362
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester.","definition_xrefs":["RESID:AA0279"],"gene_count":0,"genotype_count":0,"name":"obsolete peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester (obsolete GO:0018362)","synonyms":[{"name":"peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester","type":"exact"}],"termid":"GO:0018362"}


id: PBO:0089970
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4-phosphoerythronate phosphastase/2-phosphoglycolate phophatase, involved in detoxification of glycolytic by-products","termid":"PBO:0089970"}


id: MONDO:0013387
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"KCNQ2-related epileptic encephalopathy is a severe form of neonatal epilepsy that usually manifests in newborns during the first week of life with seizures (that affect alternatively both sides of the body), often accompanied by clonic jerking or more complex motor behavior, as well as signs of encephalopathy such as diffuse hypotonia, limb spasticity, lack of visual fixation and tracking and mild to moderate intellectual deficiency. The severity can range from controlled to intractable seizures and mild/moderate to severe intellectual disability.","definition_xrefs":["Orphanet:439218"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0005027"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 7","secondary_identifiers":["UMLS:C3150986","MEDGEN:462336","DOID:0080462","GARD:13060","OMIM:613720"],"synonyms":[{"name":"DEE7","type":"exact"},{"name":"EIEE7","type":"exact"},{"name":"KCNQ2-NEE","type":"exact"},{"name":"KCNQ2-related disorders","type":"related"},{"name":"KCNQ2-related epileptic encephalopathy","type":"exact"},{"name":"KCNQ2-related neonatal epileptic encephalopathy","type":"exact"},{"name":"developmental and epileptic encephalopathy 7","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 7","type":"exact"},{"name":"epileptic encephalopathy, early infantile, type 7","type":"exact"}],"termid":"MONDO:0013387","xrefs":{"Monarch":{"xref_id":"0013387"}}}


id: PBO:0017823
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"26S proteasome regulatory particle assembly protein Nas2 (predicted)","termid":"PBO:0017823"}


id: MONDO:1010323
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Entropion that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of orbital region, non-human animal","termid":"MONDO:1011315"},{"relation_name":"is_a","term_name":"disorder of visual system, non-human animal","termid":"MONDO:1011316"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"entropion, non-human animal","secondary_identifiers":["OMIA:000337"],"termid":"MONDO:1010323","xrefs":{"Monarch":{"xref_id":"1010323"}}}


id: PATO:0001896
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structure quality inhering in a bearer by virtue of the bearer's lacking of a three dimensional space surrounded by one or more anatomical structures and containing one or more anatomical substances.","definition_xrefs":["PATOC:MAH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"structure, cavities","termid":"PATO:0002014"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unlumenized","termid":"PATO:0001896"}


id: PBO:0040492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATXN8 opposite strand lncRNA","termid":"PBO:0040492"}


id: SO:0001558
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant which changes the localization of a polypeptide with respect to a reference sequence.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polypeptide_function_variant","termid":"SO:0001554"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polypeptide_localization_variant","synonyms":[{"name":"polypeptide localization variant","type":"exact"}],"termid":"SO:0001558"}


id: MOD:01783
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-serine residue to N,N-dimethyl-L-serine.","definition_xrefs":["PubMed:20668449","RESID:AA0534"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-amino dimethylated residue","termid":"MOD:01686"},{"relation_name":"is_a","term_name":"N-methylated serine","termid":"MOD:01800"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"N,N-dimethyl-L-serine","synonyms":[{"name":"(2S)-2-(dimethylamino)propanoic acid","type":"exact"},{"name":"MOD_RES N,N-dimethylserine","type":"exact"},{"name":"N,N-dimethyl-L-serine","type":"exact"},{"name":"N,N-dimethylserine","type":"exact"}],"termid":"MOD:01783"}


id: GO:2000639
data:
  {"annotated_genes":["SJAG_01253","SJAG_00293","SJAG_00642"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90748,105365,111163],"is_not":false,"summary":null,"term":"GO:2000639"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of intracellular signal transduction","termid":"GO:1902532"},{"relation_name":"is_a","term_name":"regulation of SREBP signaling pathway","termid":"GO:2000638"},{"relation_name":"negatively_regulates","term_name":"SREBP signaling pathway","termid":"GO:0032933"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00293":null,"SJAG_00642":null,"SJAG_01253":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of SREBP signaling pathway","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"negative regulation of SREBP-mediated signaling pathway","type":"exact"},{"name":"negative regulation of SREBP-mediated signalling pathway","type":"exact"}],"termid":"GO:2000639","terms_by_termid":{"GO:2000639":null}}


id: PBO:0004917
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromodomain protein 2","termid":"PBO:0004917"}


id: GO:0035961
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.","definition_xrefs":["GOC:dgf","PMID:11533229"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter (obsolete GO:0035961)","synonyms":[{"name":"positive regulation of ergosterol anabolism by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"positive regulation of ergosterol anabolism by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol anabolism by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol anabolism by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol anabolism by upregulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol biosynthesis by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"positive regulation of ergosterol biosynthesis by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol biosynthesis by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol biosynthesis by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol biosynthesis by upregulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol biosynthetic process by activation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol biosynthetic process by positive regulation of transcription from Pol II promoter","type":"related"},{"name":"positive regulation of ergosterol biosynthetic process by stimulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol biosynthetic process by up regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol biosynthetic process by up-regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol biosynthetic process by upregulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol formation by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"positive regulation of ergosterol formation by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol formation by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol formation by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol formation by upregulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol synthesis by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"positive regulation of ergosterol synthesis by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"positive regulation of ergosterol synthesis by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol synthesis by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of ergosterol synthesis by upregulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:0035961"}


id: PBO:0053959
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1266","termid":"PBO:0053959"}


id: MONDO:0004901
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Syndromes which feature dyskinesias as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.","definition_xrefs":["MESH:D009069"],"direct_ancestors":[{"relation_name":"is_a","term_name":"movement disorder","termid":"MONDO:0005395"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lingual-facial-buccal dyskinesia","secondary_identifiers":["DOID:9854","ICD9:333.82","MEDGEN:57747","UMLS:C0152115","SCTID:49386006"],"synonyms":[{"name":"oro-facial dyskinesia","type":"exact"}],"termid":"MONDO:0004901","xrefs":{"Monarch":{"xref_id":"0004901"}}}


id: GO:0009078
data:
  {"annotated_genes":["SJAG_06635","SJAG_03985","SJAG_04098","SJAG_03243","SJAG_04145","SJAG_03562","SJAG_00396","SJAG_02841","SJAG_04149"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[110685],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042853"},{"annotations":[90200,102779,100317,105651,109534,109888,112697],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009098"},{"annotations":[110547],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006551"},{"annotations":[102780,110548,112698,90201,109889],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009099"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-amino acid metabolic process","termid":"GO:0170033"},{"relation_name":"is_a","term_name":"proteinogenic amino acid metabolic process","termid":"GO:0170039"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00396":null,"SJAG_02841":null,"SJAG_03243":null,"SJAG_03562":null,"SJAG_03985":null,"SJAG_04098":null,"SJAG_04145":null,"SJAG_04149":null,"SJAG_06635":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"pyruvate family amino acid metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-8964540"],"synonyms":[{"name":"pyruvate family amino acid metabolism","type":"exact"}],"termid":"GO:0009078","terms_by_termid":{"GO:0006551":null,"GO:0009098":null,"GO:0009099":null,"GO:0042853":null}}


id: GO:0050934
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).","definition_xrefs":["PMID:11858836"],"direct_ancestors":[{"relation_name":"is_a","term_name":"melanocyte differentiation","termid":"GO:0030318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"late stripe melanocyte differentiation","synonyms":[{"name":"late stripe melanocyte cell differentiation","type":"exact"},{"name":"late stripe melanophore differentiation","type":"exact"}],"termid":"GO:0050934"}


id: FYPO:0006690
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell proceeds through the mitotic metaphase/anaphase transition in the presence of an uncorrected problem (such as chromosome structure or kinetochore attachment), and as a result undergoes abnormal chromosome segregation and subsequently dies.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete mitotic catastrophe with abnormal chromosome segregation (obsolete FYPO:0006690)","synonyms":[{"name":"mitotic catastrophe with abnormal chromosome segregation during mitotic cell cycle","type":"related"},{"name":"mitotic catastrophe with abnormal chromosome segregation during vegetative growth","type":"exact"}],"termid":"FYPO:0006690"}


id: SO:0002221
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A regulatory_region including the Transcription Start Site (TSS) of a gene and serving as a platform for Pre-Initiation Complex (PIC) assembly, enabling transcription of a gene under certain conditions.","direct_ancestors":[{"relation_name":"is_a","term_name":"promoter","termid":"SO:0000167"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic_promoter","synonyms":[{"name":"Eukaryotic promoter","type":"exact"}],"termid":"SO:0002221"}


id: PBO:0012560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome complex subunit alpha 6 subunit Pre5 (predicted)","termid":"PBO:0012560"}


id: GO:1900608
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of tensidol B.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ketone biosynthetic process","termid":"GO:0042181"},{"relation_name":"is_a","term_name":"amide biosynthetic process","termid":"GO:0043604"},{"relation_name":"is_a","term_name":"secondary metabolite biosynthetic process","termid":"GO:0044550"},{"relation_name":"is_a","term_name":"carboxylic acid biosynthetic process","termid":"GO:0046394"},{"relation_name":"is_a","term_name":"tensidol B metabolic process","termid":"GO:1900606"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0019748"],"is_obsolete":false,"name":"tensidol B biosynthetic process","synonyms":[{"name":"tensidol B anabolism","type":"exact"},{"name":"tensidol B biosynthesis","type":"exact"},{"name":"tensidol B formation","type":"exact"},{"name":"tensidol B synthesis","type":"exact"}],"termid":"GO:1900608"}


id: MONDO:0700167
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Sebaceous epithelioma occurring in a dog.","definition_xrefs":["NCIT:C176701"],"direct_ancestors":[{"relation_name":"is_a","term_name":"canine neoplasm","termid":"MONDO:0700139"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"canine sebaceous gland epithelioma","termid":"MONDO:0700167","xrefs":{"Monarch":{"xref_id":"0700167"}}}


id: PBO:0068510
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U1 small nuclear 100, pseudogene","termid":"PBO:0068510"}


id: FYPO:0002248
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of mannose binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal monosaccharide binding","termid":"FYPO:0002245"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0001985","FYPO:0000652"],"is_obsolete":false,"name":"increased mannose binding","termid":"FYPO:0002248"}


id: MONDO:0006311
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A category of clonal hematopoietic disorders that have both myelodysplastic and myeloproliferative features at the time of initial presentation.","definition_xrefs":["NCIT:C27262"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloproliferative neoplasm","termid":"MONDO:0020076"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0004992","MONDO:0005046"],"is_obsolete":false,"name":"myelodysplastic/myeloproliferative neoplasm","secondary_identifiers":["UMLS:C1301355","DOID:4972","EFO:1000388","MEDGEN:226981","ICDO:9975/3","MESH:D054437","SCTID:445738007","ONCOTREE:MDS%2FMPN"],"synonyms":[{"name":"MDS-MPD","type":"broad"},{"name":"MDS/MPD","type":"broad"},{"name":"MDS/MPN","type":"exact"},{"name":"MPD-MDS","type":"exact"},{"name":"MPD/MDS","type":"exact"},{"name":"myelodysplastic myeloproliferative cancer","type":"exact"},{"name":"myelodysplastic myeloproliferative disease","type":"broad"},{"name":"myelodysplastic/myeloproliferative disease","type":"broad"},{"name":"myelodysplastic/myeloproliferative diseases","type":"broad"},{"name":"myelodysplastic/myeloproliferative disorder","type":"broad"},{"name":"myelodysplastic/myeloproliferative disorders","type":"broad"},{"name":"myelodysplastic/myeloproliferative neoplasm","type":"exact"},{"name":"myelodysplastic/myeloproliferative neoplasms","type":"exact"},{"name":"myeloproliferative/myelodysplastic disorders","type":"broad"},{"name":"myeloproliferative/myelodysplastic syndromes","type":"broad"}],"termid":"MONDO:0006311","xrefs":{"Monarch":{"xref_id":"0006311"}}}


id: MONDO:0024469
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, intermediate, or malignant cartilaginous matrix-producing neoplasm. Representative examples include osteochondroma, chondroblastoma, and chondrosarcoma.","definition_xrefs":["NCIT:C4755"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesenchymal cell neoplasm","termid":"MONDO:0002616"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chondrogenic neoplasm","secondary_identifiers":["MEDGEN:96904","UMLS:C0476147"],"synonyms":[{"name":"cartilaginous neoplasm","type":"exact"},{"name":"cartilaginous tumor","type":"exact"},{"name":"cartilaginous tumour","type":"exact"},{"name":"chondrogenic neoplasm","type":"exact"},{"name":"chondrogenic tumor","type":"exact"},{"name":"chondrogenic tumour","type":"exact"},{"name":"chondromatous neoplasm","type":"exact"},{"name":"chondromatous tumor","type":"exact"},{"name":"chondromatous tumour","type":"exact"},{"name":"neoplasm of cartilage","type":"exact"},{"name":"neoplasm of the cartilage","type":"exact"},{"name":"tumor of cartilage","type":"exact"},{"name":"tumor of the cartilage","type":"exact"},{"name":"tumour of cartilage","type":"exact"},{"name":"tumour of the cartilage","type":"exact"}],"termid":"MONDO:0024469","xrefs":{"Monarch":{"xref_id":"0024469"}}}


id: PBO:0029673
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-actomyosin_contractile_ring_displaced_from_midpoint","termid":"PBO:0029673"}


id: MONDO:0007536
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital lobar emphysema (CLE) is a respiratory abnormality characterized by respiratory distress due to hyperinflation of one or more affected lobes of the lung.","definition_xrefs":["Orphanet:1928"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete non-syndromic respiratory or mediastinal malformation (obsolete MONDO:0015221)","termid":"MONDO:0015221"},{"relation_name":"is_a","term_name":"pulmonary emphysema","termid":"MONDO:0004849"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital lobar emphysema","secondary_identifiers":["icd11.foundation:685349915","NCIT:C98895","NORD:1085","SCTID:66987001","UMLS:C0265797","OMIM:130710","MedDRA:10010456","MEDGEN:120557","GARD:2104","MESH:C535735"],"synonyms":[{"name":"emphysema, congenital lobar","type":"exact"},{"name":"infantile lobar hyperinflation","type":"exact"},{"name":"CLE","type":"exact"},{"name":"Emphysema, Congenital Lobar","type":"exact"},{"name":"congenital lobar hyperinflation","type":"exact"}],"termid":"MONDO:0007536","xrefs":{"Monarch":{"xref_id":"0007536"}}}


id: FYPO:0004543
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which any process of heterochromatin organization is abnormal in the vegetative growth phase of the life cycle. Heterochromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.","definition_xrefs":["PomBase:mah","GO:0070828"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromatin organization during vegetative growth","termid":"FYPO:0001352"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000641"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000641","FYPO:0001985","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"abnormal heterochromatin organization during vegetative growth","synonyms":[{"name":"abnormal heterochromatin organisation during vegetative growth","type":"exact"},{"name":"abnormal heterochromatin organization during mitotic cell cycle","type":"related"}],"termid":"FYPO:0004543"}


id: PBO:0041176
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"butyrophilin subfamily 2 member A1","termid":"PBO:0041176"}


id: PBO:0017085
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces pombe specific protein Mug112","termid":"PBO:0017085"}


id: PBO:0044643
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DC-STAMP domain containing 1","termid":"PBO:0044643"}


id: PBO:0058298
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4672","termid":"PBO:0058298"}


id: GO:0048548
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of endocytosis","termid":"GO:0030100"},{"relation_name":"regulates","term_name":"pinocytosis","termid":"GO:0006907"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0006810","GO:0016192","GO:0008150"],"is_obsolete":false,"name":"regulation of pinocytosis","termid":"GO:0048548"}


id: MONDO:0018361
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"secondary neonatal autoimmune disease","termid":"MONDO:0018356"},{"relation_name":"is_a","term_name":"scleroderma","termid":"MONDO:0019340"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"neonatal scleroderma","secondary_identifiers":["Orphanet:398127","UMLS:C4509425","GARD:21648","MEDGEN:1652107"],"termid":"MONDO:0018361","xrefs":{"Monarch":{"xref_id":"0018361"}}}


id: SO:0000920
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An edit to insert a cytidine.","definition_xrefs":["SO:ke"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000920 insert_C (obsolete SO:0000920)","synonyms":[{"name":"insert C","type":"exact"}],"termid":"SO:0000920"}


id: MONDO:0006812
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Constriction of arteries in the skull due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and brain ischemia that may lead to hypoxic-ischemic brain injury (hypoxia-ischemia, brain).","definition_xrefs":["MESH:D020301"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebrovascular disorder","termid":"MONDO:0011057"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intracranial vasospasm","secondary_identifiers":["UMLS:C0751895","DOID:13100","EFO:1000994","MEDGEN:199760"],"termid":"MONDO:0006812","xrefs":{"Monarch":{"xref_id":"0006812"}}}


id: GO:0004343
data:
  {"annotated_genes":["SJAG_00519"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70472],"is_not":false,"summary":null,"term":"GO:0004343"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H+.","definition_xrefs":["EC:2.3.1.4","RHEA:10292"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acetyltransferase activity","termid":"GO:0008080"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00519":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016740","GO:0016746"],"is_obsolete":false,"name":"glucosamine 6-phosphate N-acetyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:GLUCOSAMINEPNACETYLTRANS-RXN","KEGG_REACTION:R02058","Reactome:R-HSA-449734"],"synonyms":[{"name":"D-glucosamine-6-P N-acetyltransferase activity","type":"related"},{"name":"N-acetylglucosamine-6-phosphate synthase activity","type":"related"},{"name":"acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity","type":"related"},{"name":"aminodeoxyglucosephosphate acetyltransferase activity","type":"related"},{"name":"glucosamine 6-phosphate acetylase activity","type":"related"},{"name":"glucosamine-6-phosphate acetylase activity","type":"related"},{"name":"glucosamine-phosphate N-acetyltransferase activity","type":"exact"},{"name":"phosphoglucosamine N-acetylase activity","type":"related"},{"name":"phosphoglucosamine acetylase activity","type":"related"},{"name":"phosphoglucosamine transacetylase activity","type":"related"}],"termid":"GO:0004343","terms_by_termid":{"GO:0004343":null}}


id: MONDO:0100148
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A complex neurodevelopmental disorder that is transmitted via X-linked inheritance, and is characterized by intellectual disability, autism and epilepsy.","definition_xrefs":["PMID:25644381","PMID:29267967"],"direct_ancestors":[{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"},{"relation_name":"is_a","term_name":"complex neurodevelopmental disorder","termid":"MONDO:0100038"},{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"X-linked complex neurodevelopmental disorder","synonyms":[{"name":"X-linked complex neurodevelopmental disorder","type":"exact"}],"termid":"MONDO:0100148","xrefs":{"Monarch":{"xref_id":"0100148"}}}


id: SO:0001240
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The region of a gene from the 5' most TSS to the 3' TSS.","definition_xrefs":["BBOP:nw"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0001240 TSS_region (obsolete SO:0001240)","synonyms":[{"name":"TSS region","type":"exact"}],"termid":"SO:0001240"}


id: PBO:0065585
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prothymosin alpha pseudogene 1","termid":"PBO:0065585"}


id: GO:0097390
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["GOC:rv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemokine production","termid":"GO:0032602"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"chemokine (C-X-C motif) ligand 12 production","synonyms":[{"name":"CXCL12 production","type":"exact"}],"termid":"GO:0097390"}


id: PBO:0113201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Methionine-R-sulfoxide reductase; reduces the R enantiomer of free Met-SO, in contrast to Ycl033Cp which reduces Met-R-SO in a peptide linkage; has a role in protection against oxidative stress; capable of binding and degrading patulin, a polyketide mycotoxin, forming E-ascladiol; relative distribution to the nucleus increases upon DNA replication stress","termid":"PBO:0113201"}


id: FYPO:0006793
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A biological process phenotype in which the specificity between a meiotic driver gene and a drive suppressor gene differs from that observed when both genes are wild type. Meiotic drive results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to such that are unequally represented (i.e. the \\\"driver\\\" is overrepresented) among the surviving products of meiosis.","definition_xrefs":["PomBase:mah","PMID:30475921"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal biological process","termid":"FYPO:0005447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"altered meiotic drive suppression specificity","synonyms":[{"name":"abnormal meiotic drive suppression specificity","type":"exact"},{"name":"abnormal specificity of suppression of meiotic drive","type":"exact"}],"termid":"FYPO:0006793"}


id: PATO:0000417
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000417 absolute number value (obsolete PATO:0000417)","termid":"PATO:0000417"}


id: GO:1902309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation.","definition_xrefs":["GOC:TermGenie","GOC:rl","GOC:mtg_cardiac_conduct_nov11","GOC:BHF","PMID:11953308"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of peptidyl-serine dephosphorylation (obsolete GO:1902309)","synonyms":[{"name":"down regulation of peptidyl-serine dephosphorylation","type":"exact"},{"name":"down-regulation of peptidyl-serine dephosphorylation","type":"exact"},{"name":"downregulation of peptidyl-serine dephosphorylation","type":"exact"},{"name":"inhibition of peptidyl-serine dephosphorylation","type":"narrow"}],"termid":"GO:1902309"}


id: PBO:0116295
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcriptional repressor, activator; role in adjustment to osmotic stress including modulation of mating efficiency; involved in repression of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, ergosterol biosynthetic genes in response to hyperosmotic stress; contributes to recruitment of Tup1p-Cyc8p general repressor to promoters; relocalizes to cytosol under hypoxia; ethanol stress increases the frequency of [MOT3+] formation, while hypoxia eliminates [MOT3+]","termid":"PBO:0116295"}


id: PBO:0046942
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 66 member D","termid":"PBO:0046942"}


id: PBO:0063222
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PCDH9 antisense RNA 2","termid":"PBO:0063222"}


id: GO:1905758
data:
  {"annotated_genes":["SJAG_04776","SJAG_04666","SJAG_04597"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[87053,91928,93921],"is_not":false,"summary":null,"term":"GO:1905758"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis.","definition_xrefs":["PMID:27898700","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cellular component biogenesis","termid":"GO:0044089"},{"relation_name":"is_a","term_name":"positive regulation of mitotic cytokinetic process","termid":"GO:1903438"},{"relation_name":"is_a","term_name":"regulation of primary cell septum biogenesis","termid":"GO:1905756"},{"relation_name":"positively_regulates","term_name":"primary cell septum biogenesis","termid":"GO:0031671"}],"gene_count":3,"genes_by_uniquename":{"SJAG_04597":null,"SJAG_04666":null,"SJAG_04776":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0000281"},{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0000281"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0000281","GO:0008150","GO:0007049","GO:0044085"],"is_obsolete":false,"name":"positive regulation of primary cell septum biogenesis","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1905758","terms_by_termid":{"GO:1905758":null}}


id: MONDO:0009445
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ichthyosis-hepatosplenomegaly-cerebellar degeneration syndrome is characterized by ichthyosis, hepatosplenomegaly and late-onset cerebellar ataxia. It has been described in two brothers. Transmission is either autosomal recessive or X-linked.","definition_xrefs":["Orphanet:2274"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary ataxia","termid":"MONDO:0100309"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ichthyosis-hepatosplenomegaly-cerebellar degeneration syndrome","secondary_identifiers":["MEDGEN:266150","MESH:C535727","SCTID:403779009","UMLS:C1275088","GARD:1993","OMIM:242520","ICD9:571.8"],"synonyms":[{"name":"Dykes Markes Harper syndrome","type":"related"},{"name":"Dykes-Markes-Harper syndrome","type":"exact"},{"name":"Dykes-Marks-Harper syndrome","type":"exact"},{"name":"ichthyosis, hepatosplenomegaly, and cerebellar degeneration","type":"related"}],"termid":"MONDO:0009445","xrefs":{"Monarch":{"xref_id":"0009445"}}}


id: MONDO:0020042
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete syndrome with 46,XY disorder of sex development (obsolete MONDO:0020042)","secondary_identifiers":["NANDO:2200393","Orphanet:98087"],"synonyms":[{"name":"syndrome with 46,XY DSD","type":"exact"}],"termid":"MONDO:0020042","xrefs":{"Monarch":{"xref_id":"0020042"}}}


id: MONDO:0010054
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spinal muscular atrophy with intellectual disability","secondary_identifiers":["MEDGEN:376518","UMLS:C1849109","MESH:C564807","OMIM:271109"],"synonyms":[{"name":"spinal muscular atrophy with intellectual disability","type":"exact"},{"name":"spinal muscular atrophy with mental retardation","type":"exact"}],"termid":"MONDO:0010054","xrefs":{"Monarch":{"xref_id":"0010054"}}}


id: GO:0021647
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.","definition_xrefs":["GOC:dgh","GOC:jid","ISBN:0838580343","GOC:cls","GO_REF:0000021","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve maturation","termid":"GO:0021605"},{"relation_name":"part_of","term_name":"vestibulocochlear nerve development","termid":"GO:0021562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"vestibulocochlear nerve maturation","synonyms":[{"name":"CN VIII maturation","type":"related"},{"name":"auditory nerve maturation","type":"related"}],"termid":"GO:0021647"}


id: PBO:0055113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2532","termid":"PBO:0055113"}


id: MONDO:1010639
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Factor XII deficiency that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"factor XII deficiency, non-human animal","termid":"MONDO:1010074"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"factor XII deficiency, dog","secondary_identifiers":["OMIA:000364-9615"],"termid":"MONDO:1010639","xrefs":{"Monarch":{"xref_id":"1010639"}}}


id: FYPO:0003926
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a cell contains a larger number of sites where replication forks have converged than normal. Additional converged forks are usually detected at sites that are normally replicated unidirectionally.","definition_xrefs":["PomBase:mah","PMID:22426534"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vegetative cell phenotype","termid":"FYPO:0003755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"increased number of converged replication forks","synonyms":[{"name":"increased converged forks","type":"exact"},{"name":"increased number of converged replication forks during mitotic cell cycle","type":"related"},{"name":"increased number of converged replication forks during vegetative growth","type":"exact"}],"termid":"FYPO:0003926"}


id: PBO:0034083
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-conduit_for","termid":"PBO:0034083"}


id: PBO:0079335
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis-specific transcript, Y-linked 21","termid":"PBO:0079335"}


id: PBO:0062273
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily H member 4 pseudogene","termid":"PBO:0062273"}


id: PBO:0047867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, aphidicolin type, common, fra(2)(q31)","termid":"PBO:0047867"}


id: SO:0001278
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"1-methylinosine is a modified inosine.","direct_ancestors":[{"relation_name":"is_a","term_name":"modified_inosine","termid":"SO:0001274"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"one_methylinosine","secondary_identifiers":["RNAMOD:018"],"synonyms":[{"name":"1-methylinosine","type":"exact"},{"name":"m1I","type":"exact"},{"name":"one methylinosine","type":"exact"}],"termid":"SO:0001278"}


id: PBO:0056533
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MCCC1 antisense RNA 1","termid":"PBO:0056533"}


id: PBO:0000969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TATA-binding protein associated factor Taf2 (predicted)","termid":"PBO:0000969"}


id: MONDO:0013014
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A spondyloepimetaphyseal dysplasia characterized by severe short stature, facial dysmorphism and characteristic radiographic findings.","definition_xrefs":["Orphanet:171866"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"spondyloepiphyseal dysplasia","termid":"MONDO:0016761"},{"relation_name":"is_a","term_name":"spondyloepimetaphyseal dysplasia","termid":"MONDO:0100510"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"spondyloepimetaphyseal dysplasia, aggrecan type","secondary_identifiers":["GARD:10513","icd11.foundation:1133152894","OMIM:612813","MESH:C567558","SCTID:719165004","UMLS:C2748544","MEDGEN:411237"],"synonyms":[{"name":"SEMD, aggrecan type","type":"exact"},{"name":"SEMDAG","type":"related"},{"name":"spondyloepimetaphyseal dysplasia, aggrecan type","type":"exact"}],"termid":"MONDO:0013014","xrefs":{"Monarch":{"xref_id":"0013014"}}}


id: PBO:0110261
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA cleavage and polyadenylation specificity factor complex RNA-binding subunit Pcf11","termid":"PBO:0110261"}


id: PBO:0054721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2130","termid":"PBO:0054721"}


id: PBO:0068777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 14, pseudogene","termid":"PBO:0068777"}


id: PATO:0000324
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color hue with medium wavelength of that portion of the visible spectrum lying between orange and green, evoked in the human observer by radiant energy with wavelengths of approximately 570 to 590 nanometers.","definition_xrefs":["Dictionary:http://dictionary.reference.com/"],"direct_ancestors":[{"relation_name":"is_a","term_name":"color","termid":"PATO:0000014"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"yellow","termid":"PATO:0000324"}


id: FYPO:0002719
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to septum","termid":"FYPO:0002718"},{"relation_name":"is_a","term_name":"decreased protein localization to cell division site","termid":"FYPO:0002869"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000138","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein localization to septum","synonyms":[{"name":"decreased protein localisation to septum","type":"exact"},{"name":"decreased protein localization to cell septum","type":"exact"},{"name":"decreased protein localization to division septum","type":"exact"},{"name":"decreased protein localization to septum during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to septum during vegetative growth","type":"exact"},{"name":"reduced protein localization to septum","type":"exact"}],"termid":"FYPO:0002719"}


id: MONDO:0010874
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enteropathy, familial, with villous edema and immunoglobulin G2 deficiency","secondary_identifiers":["UMLS:C1838238","MEDGEN:324980","OMIM:600351","MESH:C563949"],"synonyms":[{"name":"enteropathy, familial, with villous edema and immunoglobulin G2 deficiency","type":"exact"}],"termid":"MONDO:0010874","xrefs":{"Monarch":{"xref_id":"0010874"}}}


id: PBO:0061109
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NLR family pyrin domain containing 2","termid":"PBO:0061109"}


id: PBO:0051402
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda like polypeptide 2, pseudogene","termid":"PBO:0051402"}


id: PBO:0063405
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PDCL3 pseudogene 1","termid":"PBO:0063405"}


id: PBO:0041911
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CBLL1 pseudogene 1","termid":"PBO:0041911"}


id: GO:0038188
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A G protein-coupled receptor signaling pathway initiated by cholecystokinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["PMID:11181948","GOC:jc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor signaling pathway","termid":"GO:0007186"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"cholecystokinin signaling pathway","secondary_identifiers":["Wikipedia:Cholecystokinin"],"synonyms":[{"name":"CCK signaling","type":"exact"},{"name":"cholecystokinin receptor signaling pathway","type":"related"}],"termid":"GO:0038188"}


id: PR:O94709
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pdx1 gene.","definition_xrefs":["UniProtKB:O94709","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyruvate dehydrogenase protein X component, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1259.09c","synonyms":[{"name":"Spom972h-pdx1","type":"exact"},{"name":"dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94709"}


id: PBO:0035945
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_rate_of_deactivation_of_mitotic_spindle_assembly_checkpoint","termid":"PBO:0035945"}


id: GO:0033270
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.","definition_xrefs":["GOC:mh","GOC:mah","NIF_Subcellular:sao936144858"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"main axon","termid":"GO:0044304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"paranode region of axon","secondary_identifiers":["NIF_Subcellular:sao234066064"],"synonyms":[{"name":"paranode","type":"exact"}],"termid":"GO:0033270"}


id: PBO:0092002
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"this gene is located in the silent mating type region mat2 and is therefore not expressed. It is only transcribed when at the mat1 locus, which is the mating type configuration of h+ cells. The S. pombe reference strain is h- mating type and express h- specific mating genes from the mat1 locus. The silenced mat2 genes are therefore annotated with mat1 h+ specific information","termid":"PBO:0092002"}


id: PBO:0073340
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serpin family B member 2","termid":"PBO:0073340"}


id: PBO:0084756
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial matrix protein; required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p","termid":"PBO:0084756"}


id: PATO:0000470
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An amount which is relatively high.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"present","termid":"PATO:0000467"},{"relation_name":"is_a","term_name":"increased quality","termid":"PATO:0002300"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased amount","secondary_identifiers":["PATO:0000420","PATO:0000650"],"synonyms":[{"name":"accessory","type":"related"},{"name":"increased","type":"related"},{"name":"increased number","type":"exact"},{"name":"present in greater numbers in organism","type":"exact"},{"name":"supernumerary","type":"exact"}],"termid":"PATO:0000470"}


id: PR:O94649
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- atg2 gene.","definition_xrefs":["UniProtKB:O94649","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy-related protein 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC31E1.01c","synonyms":[{"name":"Spom972h-atg2","type":"exact"},{"name":"meiotically up-regulated gene 36 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94649"}


id: PBO:0083246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; gene expression induced by heat","termid":"PBO:0083246"}


id: PR:O74359
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC28E12.02 gene.","definition_xrefs":["UniProtKB:O74359","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 60 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC28E12.02","synonyms":[{"name":"Spom972h-SPBC28E12.02","type":"exact"}],"termid":"PR:O74359"}


id: GO:0050612
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: A + arsenite + H2O = AH(2) + arsenate + 2 H+.","definition_xrefs":["RHEA:18449","EC:1.20.99.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on phosphorus or arsenic in donors","termid":"GO:0030613"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"arsenate reductase (donor) activity","secondary_identifiers":["KEGG_REACTION:R05752","MetaCyc:1.20.99.1-RXN"],"synonyms":[{"name":"arsenate:(acceptor) oxidoreductase activity","type":"related"},{"name":"arsenate:acceptor oxidoreductase activity","type":"related"}],"termid":"GO:0050612"}


id: PBO:0038853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADAM metallopeptidase with thrombospondin type 1 motif 20","termid":"PBO:0038853"}


id: PBO:0044631
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"doublecortin like kinase 2","termid":"PBO:0044631"}


id: GO:1902841
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway.","definition_xrefs":["GOC:TermGenie","PMID:24004945","GO_REF:0000058","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"regulates","term_name":"netrin-activated signaling pathway","termid":"GO:0038007"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of netrin-activated signaling pathway","synonyms":[{"name":"regulation of netrin signaling pathway","type":"exact"},{"name":"regulation of netrin-activated signal transduction pathway","type":"exact"},{"name":"regulation of netrin-activated signalling pathway","type":"exact"},{"name":"regulation of netrin-mediated signaling pathway","type":"exact"}],"termid":"GO:1902841"}


id: PBO:0063085
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progestin and adipoQ receptor family member 4","termid":"PBO:0063085"}


id: GO:0052871
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] = 13-hydroxy-alpha-tocopherol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].","definition_xrefs":["RHEA:45108"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"alpha-tocopherol omega-hydroxylase activity","secondary_identifiers":["MetaCyc:RXN-11003"],"synonyms":[{"name":"alpha-tocopherol 13-hydroxylase activity","type":"exact"}],"termid":"GO:0052871"}


id: PBO:0076903
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed 101","termid":"PBO:0076903"}


id: PR:O94525
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC609.01 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94525"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized ribonuclease C609.01 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC609.01","synonyms":[{"name":"Spom972h-SPBC609.01","type":"exact"}],"termid":"PR:O94525"}


id: GO:1901158
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of neomycin.","definition_xrefs":["UniPathway:UPA00969","GOC:TermGenie","GOC:yaf","MetaCyc:PWY-7016"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoglycoside antibiotic biosynthetic process","termid":"GO:0030648"},{"relation_name":"is_a","term_name":"polyol biosynthetic process","termid":"GO:0046173"},{"relation_name":"is_a","term_name":"neomycin metabolic process","termid":"GO:1901156"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"neomycin biosynthetic process","synonyms":[{"name":"neomycin anabolism","type":"exact"},{"name":"neomycin biosynthesis","type":"exact"},{"name":"neomycin formation","type":"exact"},{"name":"neomycin synthesis","type":"exact"}],"termid":"GO:1901158"}


id: MONDO:0001142
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease involving the saliva-secreting gland.","direct_ancestors":[{"relation_name":"is_a","term_name":"mouth disorder","termid":"MONDO:0006858"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"salivary gland disorder","secondary_identifiers":["EFO:0008581","ICD9:527.9","MESH:D012466","DOID:10854","ICD9:527.8","SCTID:10890000","MEDGEN:892384","UMLS:C0149772","NCIT:C26879"],"synonyms":[{"name":"disease of saliva-secreting gland","type":"exact"},{"name":"disease or disorder of saliva-secreting gland","type":"exact"},{"name":"disorder of saliva-secreting gland","type":"exact"},{"name":"non-neoplastic salivary gland disease","type":"narrow"},{"name":"saliva-secreting gland disease","type":"exact"},{"name":"saliva-secreting gland disease or disorder","type":"exact"},{"name":"salivary gland disease","type":"exact"},{"name":"salivary gland disorder","type":"exact"}],"termid":"MONDO:0001142","xrefs":{"Monarch":{"xref_id":"0001142"}}}


id: PBO:0074881
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 60","termid":"PBO:0074881"}


id: PBO:0081968
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger RANBP2-type containing 2","termid":"PBO:0081968"}


id: PBO:0068948
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 192, pseudogene","termid":"PBO:0068948"}


id: PBO:0091219
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sub-telomeric 5Tm protein family Ftm2","termid":"PBO:0091219"}


id: PBO:0087849
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Trans-aconitate methyltransferase; cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle","termid":"PBO:0087849"}


id: GO:0021766
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the hippocampus over time from its initial formation until its mature state.","definition_xrefs":["ISBN:0878937420","UBERON:0002421","GO_REF:0000021","GOC:dph","GOC:jid","GOC:cls","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"pallium development","termid":"GO:0021543"},{"relation_name":"part_of","term_name":"limbic system development","termid":"GO:0021761"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hippocampus development","synonyms":[{"name":"hippocampal formation development","type":"exact"}],"termid":"GO:0021766"}


id: PBO:0089259
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cdc42 GTPase complex scaffold subunit Scd2","termid":"PBO:0089259"}


id: PBO:0036048
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-curved_mitotic_spindle_during_anaphase_B","termid":"PBO:0036048"}


id: PBO:0065311
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine protease 33","termid":"PBO:0065311"}


id: GO:0060810
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.","definition_xrefs":["GOC:sdb_2009","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular mRNA localization","termid":"GO:0008298"},{"relation_name":"part_of","term_name":"pattern specification process","termid":"GO:0007389"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"intracellular mRNA localization involved in pattern specification process","synonyms":[{"name":"intracellular mRNA localisation involved in pattern specification process","type":"exact"}],"termid":"GO:0060810"}


id: PBO:0086717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane domains","termid":"PBO:0086717"}


id: MOD:00909
data:
  {"annotated_genes":["SJAG_01671"],"annotation_feature_type":"gene","cv_annotations":{"PSI-MOD":[{"annotations":[80166],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00226"}]},"cv_name":"PSI-MOD","definition":"A protein modification that modifies an L-histidine residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by amino acid modified","termid":"MOD:01157"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01671":null},"genotype_count":0,"is_obsolete":false,"name":"modified L-histidine residue","references_by_uniquename":{"PMID:36408920":null},"synonyms":[{"name":"ModHis","type":"exact"}],"termid":"MOD:00909","terms_by_termid":{"MOD:00226":null}}


id: GO:0035575
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.","definition_xrefs":["PMID:26214369","PMID:20622853","PMID:32209475"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"},{"relation_name":"is_a","term_name":"histone H4 demethylase activity","termid":"GO:0141058"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0032452"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0032452","GO:0003824","GO:0140096"],"is_obsolete":false,"name":"histone H4K20 demethylase activity","secondary_identifiers":["Reactome:R-HSA-2172678"],"synonyms":[{"name":"histone H4-K20 demethylase activity","type":"exact"},{"name":"histone H4-methyl-lysine-20 demethylase activity","type":"exact"},{"name":"histone H4K20me demethylase activity","type":"exact"},{"name":"histone demethylase activity (H4-K20 specific)","type":"exact"},{"name":"histone demethylase activity (H4K20-specific)","type":"exact"}],"termid":"GO:0035575"}


id: GO:0050666
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amino acid metabolic process","termid":"GO:0006521"},{"relation_name":"is_a","term_name":"regulation of sulfur amino acid metabolic process","termid":"GO:0031335"},{"relation_name":"regulates","term_name":"homocysteine metabolic process","termid":"GO:0050667"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006790"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006790","GO:0006520","GO:0044281"],"is_obsolete":false,"name":"regulation of homocysteine metabolic process","synonyms":[{"name":"regulation of Hcy metabolic process","type":"exact"},{"name":"regulation of Hcy metabolism","type":"exact"},{"name":"regulation of homocysteine metabolism","type":"exact"}],"termid":"GO:0050666"}


id: GO:1900020
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein kinase C activity.","definition_xrefs":["GOC:signaling","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein serine/threonine kinase activity","termid":"GO:0071902"},{"relation_name":"is_a","term_name":"regulation of protein kinase C activity","termid":"GO:1900019"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein kinase C activity","synonyms":[{"name":"positive regulation of PKC","type":"related"},{"name":"positive regulation of PKC activity","type":"exact"},{"name":"up regulation of PKC","type":"related"},{"name":"up regulation of PKC activity","type":"exact"}],"termid":"GO:1900020"}


id: PBO:0042432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell division cycle 37 pseudogene 1","termid":"PBO:0042432"}


id: FYPO:0004704
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more cytoplasmic microtubules than normal during interphase of the mitotic cell cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubules present in increased numbers","termid":"FYPO:0004538"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0002399"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000054","FYPO:0001985","FYPO:0002399","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"interphase microtubules present in increased numbers","synonyms":[{"name":"cytoplasmic microtubules present in greater numbers","type":"exact"},{"name":"cytoplasmic microtubules present in increased numbers during mitotic interphase","type":"exact"},{"name":"increased level of interphase MTs","type":"exact"},{"name":"interphase cytoplasmic microtubules present in increased numbers","type":"exact"},{"name":"interphase microtubules present in increased numbers during mitotic cell cycle","type":"related"},{"name":"interphase microtubules present in increased numbers during vegetative growth","type":"exact"}],"termid":"FYPO:0004704"}


id: MONDO:0100204
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease caused by infection with parainfluenza virus type 2.","definition_xrefs":["MONDO:patterns/infectious_disease_by_agent","PMID:27197630"],"direct_ancestors":[{"relation_name":"is_a","term_name":"parainfluenza infectious disease","termid":"MONDO:0100197"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"parainfluenza virus type 2 infectious disease","synonyms":[{"name":"human rubulavirus 2 infectious disease","type":"exact"},{"name":"infection caused by human parainfluenza virus 2","type":"exact"},{"name":"infection due to human parainfluenza virus 2","type":"exact"}],"termid":"MONDO:0100204","xrefs":{"Monarch":{"xref_id":"0100204"}}}


id: PBO:0026802
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_meiotic_recombination_double-strand_break_repair","termid":"PBO:0026802"}


id: PBO:0044531
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defender against cell death 1","termid":"PBO:0044531"}


id: PBO:0085156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nucleosome spacing factor; subunit of complex containing actin and actin-related proteins that has chromatin remodeling activity and 3' to 5' DNA helicase activity; involved in positioning and spacing of nucleosomes over most genes independently of transcription; promotes nucleosome shifts in the 3' direction; has a role in modulating stress gene transcription","termid":"PBO:0085156"}


id: GO:0001567
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: AH2 + cholesterol + O2 = 25-hydroxycholesterol + A + H2O.","definition_xrefs":["RHEA:21104"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid hydroxylase activity","termid":"GO:0008395"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","termid":"GO:0016705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"cholesterol 25-hydroxylase activity","secondary_identifiers":["EC:1.14.99.38","KEGG_REACTION:R07218","MetaCyc:1.14.99.38-RXN"],"synonyms":[{"name":"cholesterol 25-monooxygenase activity","type":"related"},{"name":"cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity","type":"related"}],"termid":"GO:0001567"}


id: PBO:0091754
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"II:g.1987118delG","termid":"PBO:0091754"}


id: PBO:0063217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protocadherin 7","termid":"PBO:0063217"}


id: PATO:0001268
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of brown hue and low saturation.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brown","termid":"PATO:0000952"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"desaturated brown","synonyms":[{"name":"pale brown","type":"exact"}],"termid":"PATO:0001268"}


id: FYPO:0004877
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) is decreased at specific genes that are transcriptionally up-regulated during mitosis.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased chromatin binding","termid":"FYPO:0002577"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000702"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000702","FYPO:0000652","FYPO:0000707"],"is_obsolete":false,"name":"decreased chromatin binding at mitotically up-regulated genes","synonyms":[{"name":"decreased chromatin binding at mitotically upregulated gene","type":"exact"},{"name":"reduced chromatin binding at mitotically up-regulated genes","type":"exact"}],"termid":"FYPO:0004877"}


id: GO:0090368
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.","definition_xrefs":["GOC:jp","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amino acid metabolic process","termid":"GO:0006521"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"ornithine metabolic process","termid":"GO:0006591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006520"],"is_obsolete":false,"name":"regulation of ornithine metabolic process","termid":"GO:0090368"}


id: PBO:0088124
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity; involved in control of cytosolic Ca2+ and K+ concentrations; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter","termid":"PBO:0088124"}


id: PBO:0045532
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deltex E3 ubiquitin ligase 3","termid":"PBO:0045532"}


id: PBO:0065710
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudouridine synthase like 1","termid":"PBO:0065710"}


id: GO:0086060
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.","definition_xrefs":["GOC:mtg_cardiac_conduct_nov11","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"voltage-gated sodium channel activity involved in cardiac muscle cell action potential","termid":"GO:0086006"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"voltage-gated sodium channel activity involved in AV node cell action potential","synonyms":[{"name":"voltage-gated sodium channel activity involved in AV node cardiac muscle cell action potential","type":"exact"},{"name":"voltage-gated sodium channel activity involved in atrioventricular node cardiac muscle cell action potential","type":"exact"}],"termid":"GO:0086060"}


id: MONDO:1011569
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neuronal ceroid lipofuscinosis that occurs in crab-eating macaque.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuronal ceroid lipofuscinosis, non-human animal","termid":"MONDO:1011430"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neuronal ceroid lipofuscinosis, crab-eating macaque","secondary_identifiers":["OMIA:000181-9541"],"termid":"MONDO:1011569","xrefs":{"Monarch":{"xref_id":"1011569"}}}


id: PBO:0089089
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRC complex (ER membrane insertion) TPR repeat subunit Sgt2","termid":"PBO:0089089"}


id: MONDO:0970959
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare form of conus region spinal cord lipoma characterized by its location where the interface between the lipoma and the spinal cord is strictcly above the level of the tip of the conus. The tip of the conus is readily delineated.","definition_xrefs":["Orphanet:645294"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extramedullary conus spinal cord lipoma","termid":"MONDO:0968987"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"posterior extramedullary conus spinal cord lipoma","secondary_identifiers":["UMLS:C5816725","MEDGEN:1853127"],"termid":"MONDO:0970959","xrefs":{"Monarch":{"xref_id":"0970959"}}}


id: GO:0102275
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: malonyl-CoA(5-) + an L-cysteine-S-conjugate = coenzyme A + H+ + an N-malonyl-L-cysteine-S-conjugate.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete cysteine-S-conjugate N-malonyl transferase activity (obsolete GO:0102275)","termid":"GO:0102275"}


id: PBO:0087051
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L24A; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24A has a paralog, RPL24B, that arose from the whole genome duplication","termid":"PBO:0087051"}


id: MONDO:0010435
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nystagmus","termid":"MONDO:0005712"},{"relation_name":"is_a","term_name":"GPR143-related foveal hypoplasia","termid":"MONDO:0700230"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"nystagmus 6, congenital, X-linked","secondary_identifiers":["UMLS:C3151752","MEDGEN:463102","DOID:0111795","OMIM:300814"],"synonyms":[{"name":"NYS6","type":"related"},{"name":"NYSTAGMUS 6, congenital, X-linked","type":"related"},{"name":"nystagmus 6, congenital, X-linked","type":"exact"},{"name":"nystagmus 6, congenital, X-linked, X-linked recessive","type":"exact"}],"termid":"MONDO:0010435","xrefs":{"Monarch":{"xref_id":"0010435"}}}


id: PBO:0034515
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_protein_localization_to_plasma_membrane_at_cell_division_site_during_vegetative_growth","termid":"PBO:0034515"}


id: MONDO:0019631
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A developmental ocular anomaly in which the primary vitreous body and its surrounding hyaloid vasculature failed to regress. It is usually unilateral and characterized by cataract; microphthalmos (small eyeballs), and retrolenticular fibrovascular tissue. (from Yanoff: Ophthalmology, 2nd ed.)","definition_xrefs":["MESH:D054514"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitreous disorder","termid":"MONDO:0004860"},{"relation_name":"is_a","term_name":"congenital vitreoretinal dysplasia","termid":"MONDO:0020247"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0002320"],"is_obsolete":false,"name":"persistent hyperplastic primary vitreous","secondary_identifiers":["icd11.foundation:1011137326","NCIT:C161554","DOID:0060282","MEDGEN:120583","SCTID:314270008","OMIMPS:221900","Orphanet:91495","GARD:16803","UMLS:C0266568"],"synonyms":[{"name":"PFVS","type":"exact"},{"name":"PHPV","type":"exact"},{"name":"congenital retinal detachment","type":"exact"},{"name":"ncRNA disease","type":"exact"},{"name":"non-syndromic congenital retinal non-attachment","type":"exact"},{"name":"persistent fetal vasculature syndrome","type":"exact"},{"name":"persistent foetal vasculature syndrome","type":"exact"}],"termid":"MONDO:0019631","xrefs":{"Monarch":{"xref_id":"0019631"}}}


id: GO:0052521
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by host of symbiont phagocytosis (obsolete GO:0052521)","synonyms":[{"name":"activation by host of symbiont phagocytosis","type":"narrow"},{"name":"stimulation by host of symbiont phagocytosis","type":"narrow"},{"name":"up regulation by host of symbiont phagocytosis","type":"exact"},{"name":"up-regulation by host of symbiont phagocytosis","type":"exact"},{"name":"upregulation by host of symbiont phagocytosis","type":"exact"}],"termid":"GO:0052521"}


id: PR:Q92351
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pcp1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q92351"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spindle pole body protein pcp1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC6G9.06c","synonyms":[{"name":"Spom972h-pcp1","type":"exact"}],"termid":"PR:Q92351"}


id: GO:0140588
data:
  {"annotated_genes":["SJAG_00682","SJAG_00796","SJAG_01067","SJAG_03926","SJAG_03418","SJAG_05019","SJAG_02606","SJAG_01831"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[87325,89185,90434,95742,107204,107285,110002,116307],"is_not":false,"summary":null,"term":"GO:0140588"}]},"cv_name":"biological_process","definition":"A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome.","definition_xrefs":["PMID:32213323"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromatin organization","termid":"GO:0006325"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00682":null,"SJAG_00796":null,"SJAG_01067":null,"SJAG_01831":null,"SJAG_02606":null,"SJAG_03418":null,"SJAG_03926":null,"SJAG_05019":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006325"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006325","GO:0008150"],"is_obsolete":false,"name":"chromatin looping","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"DNA loop extrusion","type":"exact"},{"name":"DNA looping","type":"broad"},{"name":"chromatin folding","type":"related"},{"name":"chromatin loop assembly","type":"exact"}],"termid":"GO:0140588","terms_by_termid":{"GO:0140588":null}}


id: PBO:0041490
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 12 open reading frame 40","termid":"PBO:0041490"}


id: PBO:0041529
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 16 open reading frame 92","termid":"PBO:0041529"}


id: GO:1901717
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of catabolic process","termid":"GO:0009896"},{"relation_name":"is_a","term_name":"positive regulation of amino acid metabolic process","termid":"GO:0045764"},{"relation_name":"is_a","term_name":"positive regulation of small molecule metabolic process","termid":"GO:0062013"},{"relation_name":"is_a","term_name":"regulation of gamma-aminobutyric acid catabolic process","termid":"GO:1901715"},{"relation_name":"positively_regulates","term_name":"gamma-aminobutyric acid catabolic process","termid":"GO:0009450"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0044248"},{"rel_name":"positively_regulates","termid":"GO:0006520"},{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0044248"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044248","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"positive regulation of gamma-aminobutyric acid catabolic process","synonyms":[{"name":"activation of 4-aminobutanoate catabolic process","type":"exact"},{"name":"activation of 4-aminobutanoate catabolism","type":"exact"},{"name":"activation of 4-aminobutyrate catabolic process","type":"exact"},{"name":"activation of 4-aminobutyrate catabolism","type":"exact"},{"name":"activation of GABA catabolic process","type":"exact"},{"name":"activation of GABA catabolism","type":"exact"},{"name":"activation of gamma-aminobutyric acid breakdown","type":"exact"},{"name":"activation of gamma-aminobutyric acid catabolic process","type":"narrow"},{"name":"activation of gamma-aminobutyric acid catabolism","type":"exact"},{"name":"activation of gamma-aminobutyric acid degradation","type":"exact"},{"name":"positive regulation of 4-aminobutanoate catabolic process","type":"exact"},{"name":"positive regulation of 4-aminobutanoate catabolism","type":"exact"},{"name":"positive regulation of 4-aminobutyrate catabolic process","type":"exact"},{"name":"positive regulation of 4-aminobutyrate catabolism","type":"exact"},{"name":"positive regulation of GABA catabolic process","type":"exact"},{"name":"positive regulation of GABA catabolism","type":"exact"},{"name":"positive regulation of gamma-aminobutyric acid breakdown","type":"exact"},{"name":"positive regulation of gamma-aminobutyric acid catabolism","type":"exact"},{"name":"positive regulation of gamma-aminobutyric acid degradation","type":"exact"},{"name":"up regulation of 4-aminobutanoate catabolic process","type":"exact"},{"name":"up regulation of 4-aminobutanoate catabolism","type":"exact"},{"name":"up regulation of 4-aminobutyrate catabolic process","type":"exact"},{"name":"up regulation of 4-aminobutyrate catabolism","type":"exact"},{"name":"up regulation of GABA catabolic process","type":"exact"},{"name":"up regulation of GABA catabolism","type":"exact"},{"name":"up regulation of gamma-aminobutyric acid breakdown","type":"exact"},{"name":"up regulation of gamma-aminobutyric acid catabolic process","type":"exact"},{"name":"up regulation of gamma-aminobutyric acid catabolism","type":"exact"},{"name":"up regulation of gamma-aminobutyric acid degradation","type":"exact"},{"name":"up-regulation of 4-aminobutanoate catabolic process","type":"exact"},{"name":"up-regulation of 4-aminobutanoate catabolism","type":"exact"},{"name":"up-regulation of 4-aminobutyrate catabolic process","type":"exact"},{"name":"up-regulation of 4-aminobutyrate catabolism","type":"exact"},{"name":"up-regulation of GABA catabolic process","type":"exact"},{"name":"up-regulation of GABA catabolism","type":"exact"},{"name":"up-regulation of gamma-aminobutyric acid breakdown","type":"exact"},{"name":"up-regulation of gamma-aminobutyric acid catabolic process","type":"exact"},{"name":"up-regulation of gamma-aminobutyric acid catabolism","type":"exact"},{"name":"up-regulation of gamma-aminobutyric acid degradation","type":"exact"},{"name":"upregulation of 4-aminobutanoate catabolic process","type":"exact"},{"name":"upregulation of 4-aminobutanoate catabolism","type":"exact"},{"name":"upregulation of 4-aminobutyrate catabolic process","type":"exact"},{"name":"upregulation of 4-aminobutyrate catabolism","type":"exact"},{"name":"upregulation of GABA catabolic process","type":"exact"},{"name":"upregulation of GABA catabolism","type":"exact"},{"name":"upregulation of gamma-aminobutyric acid breakdown","type":"exact"},{"name":"upregulation of gamma-aminobutyric acid catabolic process","type":"exact"},{"name":"upregulation of gamma-aminobutyric acid catabolism","type":"exact"},{"name":"upregulation of gamma-aminobutyric acid degradation","type":"exact"}],"termid":"GO:1901717"}


id: GO:0086008
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.","definition_xrefs":["GOC:mtg_cardiac_conduct_nov11","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"voltage-gated potassium channel activity","termid":"GO:0005249"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization","termid":"GO:0086008"}


id: MONDO:0001831
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"astigmatism","termid":"MONDO:0011284"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"irregular astigmatism","secondary_identifiers":["icd11.foundation:1086387343","ICD9:367.22","MEDGEN:508922","SCTID:47099006","UMLS:C0152194","DOID:13919"],"termid":"MONDO:0001831","xrefs":{"Monarch":{"xref_id":"0001831"}}}


id: GO:0046564
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H+ + oxalate = CO2 + formate.","definition_xrefs":["RHEA:16509","EC:4.1.1.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"oxalate decarboxylase activity","secondary_identifiers":["MetaCyc:OXALATE-DECARBOXYLASE-RXN","KEGG_REACTION:R00522"],"synonyms":[{"name":"oxalate carboxy-lyase (formate-forming)","type":"related"},{"name":"oxalate carboxy-lyase activity","type":"related"}],"termid":"GO:0046564"}


id: PBO:0050721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family D (Hsp60) member 1 pseudogene 7","termid":"PBO:0050721"}


id: FYPO:0003129
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed during a cellular response to ionizing radiation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased punctate nuclear protein localization during cellular response to ionizing radiation","termid":"FYPO:0003483"},{"relation_name":"is_a","term_name":"loss of punctate nuclear protein localization","termid":"FYPO:0005863"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0000138"],"is_obsolete":false,"name":"loss of punctate nuclear protein localization during cellular response to ionizing radiation","synonyms":[{"name":"abolished punctate nuclear protein localization during cellular response to ionizing radiation","type":"exact"},{"name":"loss of punctate nuclear protein localisation during cellular response to ionising radiation","type":"exact"},{"name":"loss of punctate nuclear protein localization during cellular response to IR","type":"exact"},{"name":"loss of punctate nuclear protein localization during cellular response to ionizing radiation during mitotic cell cycle","type":"related"},{"name":"loss of punctate nuclear protein localization during cellular response to ionizing radiation during vegetative growth","type":"exact"}],"termid":"FYPO:0003129"}


id: PBO:0051648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inosine monophosphate dehydrogenase 1 pseudogene 3","termid":"PBO:0051648"}


id: PBO:0088717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aspartate kinase","termid":"PBO:0088717"}


id: MONDO:0007849
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratitis fugax hereditaria","secondary_identifiers":["MEDGEN:372107","UMLS:C1835697","OMIM:148200","MESH:C563650","Orphanet:647815"],"synonyms":[{"name":"KEFH","type":"related"},{"name":"KERATOENDOTHELIITIS fugax hereditaria","type":"related"},{"name":"Keratoendotheliitis fugax hereditaria","type":"related"},{"name":"keratitis fugax hereditaria","type":"exact"},{"name":"keratoendotheliitis fugax hereditaria","type":"exact"},{"name":"keratoendothelitis fugax hereditaria","type":"exact"}],"termid":"MONDO:0007849","xrefs":{"Monarch":{"xref_id":"0007849"}}}


id: PBO:0025497
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytosolic Trna thioUridilase","termid":"PBO:0025497"}


id: MOD:00625
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Chemical derivative","definition_xrefs":["Unimod:314"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-methylmaleimide derivatized residue","synonyms":[{"name":"Nmethylmaleimide","type":"related"}],"termid":"MOD:00625"}


id: PBO:0076478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TAP binding protein","termid":"PBO:0076478"}


id: MONDO:0020779
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any dysfunction in the growth of cartilage.","definition_xrefs":["NCIT:C34466"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal system disorder","termid":"MONDO:0005172"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cartilage development disorder","secondary_identifiers":["SCTID:67988000","UMLS:C0008449","ICD9:756.4","MEDGEN:935","ICD9:756.9"],"synonyms":[{"name":"Congenital anomaly of cartilage","type":"related"},{"name":"abnormal development of cartilage","type":"related"},{"name":"cartilage development disorder","type":"exact"},{"name":"chondrodystrophy","type":"exact"}],"termid":"MONDO:0020779","xrefs":{"Monarch":{"xref_id":"0020779"}}}


id: MONDO:0011894
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant Charcot-Marie-Tooth disease type 2E (CMT2E) is a form of axonal Charcot-Marie-Tooth disease, a peripheral sensorimotor neuropathy. CMT2E onset is in the first to 6th decade with a gait anomaly and a leg weakness that reaches the arms secondarily. Tendon reflexes are reduced or absent and, after years, all patients have a pes cavus. Other signs may be present, including hearing loss and postural tremor.","definition_xrefs":["Orphanet:99939"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease type 2","termid":"MONDO:0018993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease type 2E","secondary_identifiers":["icd11.foundation:1476045360","SCTID:717012004","UMLS:C1843225","NCIT:C134953","MESH:C537994","OMIM:607684","DOID:0110165","GARD:9193","MEDGEN:375127"],"synonyms":[{"name":"CMT 2E","type":"related"},{"name":"CMT2E","type":"exact"},{"name":"Charcot Marie Tooth disease type 2E","type":"related"},{"name":"Charcot-Marie-Tooth disease type 2 caused by mutation in NEFL","type":"exact"},{"name":"Charcot-Marie-Tooth disease, axonal, type 2E","type":"related"},{"name":"Charcot-Marie-Tooth disease, type 2E","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy type 2E","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy, type 2E","type":"related"},{"name":"NEFL Charcot-Marie-Tooth disease type 2","type":"exact"},{"name":"autosomal dominant Charcot-Marie-Tooth disease type 2E","type":"exact"}],"termid":"MONDO:0011894","xrefs":{"Monarch":{"xref_id":"0011894"}}}


id: PBO:0055732
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LMO7 antisense RNA 1","termid":"PBO:0055732"}


id: MONDO:0018322
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"HSD10 disease, infantile type is a clinical subtype of HSD10 disease, a rare neurometabolic disorder. It is characterized by normal early development until 6-18 months of life, followed by progressive neurodegeneration manifesting with developmental regression, progressive visual and hearing troubles, seizures, epilepsy, severe cardiomyopathy, lethargy, hypotonia, poor feeding, choreoathetosis, and movement disorders. Elevated blood levels of isoleucine metabolites and their excretion in urine are reported. The disease is usually fatal around 2-4 years of age.","definition_xrefs":["Orphanet:391428"],"direct_ancestors":[{"relation_name":"is_a","term_name":"HSD10 mitochondrial disease","termid":"MONDO:0010327"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"HSD10 disease, infantile type","secondary_identifiers":["UMLS:C5680025","GARD:17622","MEDGEN:1843150"],"synonyms":[{"name":"2-methyl-3-hydroxybutyric aciduria, classic type","type":"exact"},{"name":"2-methyl-3-hydroxybutyric aciduria, infantile type","type":"exact"},{"name":"2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency, classic type","type":"exact"},{"name":"2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency, infantile type","type":"exact"},{"name":"HSD10 deficiency, classic type","type":"exact"},{"name":"HSD10 deficiency, infantile type","type":"exact"},{"name":"HSD10 disease, classic type","type":"exact"},{"name":"MHBD deficiency, classic type","type":"exact"},{"name":"MHBD deficiency, infantile type","type":"exact"}],"termid":"MONDO:0018322","xrefs":{"Monarch":{"xref_id":"0018322"}}}


id: GO:0097215
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.","definition_xrefs":["GOC:yaf","PMID:20544854"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lysosomal membrane permeability","termid":"GO:0097213"},{"relation_name":"is_a","term_name":"negative regulation of membrane permeability","termid":"GO:1905709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"negative regulation of lysosomal membrane permeability","synonyms":[{"name":"negative regulation of lysosome membrane permeability","type":"exact"}],"termid":"GO:0097215"}


id: SO:0001151
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A motif of four consecutive peptide residues, of which the i+2 residue is proline, and that may contain one H-bond, which, if present, is between the main-chain CO of the first residue and the main-chain NH of the fourth and is characterized by the dihedral angles: Residue(i+1): phi ~ -60 degrees, psi ~ 120 degrees. Residue(i+2): phi ~ -90 degrees, psi ~ 0 degrees.","definition_xrefs":["SO:cb","PMID:2371257"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta_turn_type_six","termid":"SO:0001150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"beta_turn_type_six_a","synonyms":[{"name":"beta turn type six a","type":"exact"},{"name":"type VIa beta turn","type":"exact"},{"name":"type VIa turn","type":"exact"}],"termid":"SO:0001151"}


id: MONDO:0021287
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A in situ carcinoma that involves the epiglottis.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epiglottis cancer","termid":"MONDO:0004473"},{"relation_name":"is_a","term_name":"larynx carcinoma in situ","termid":"MONDO:0004696"},{"relation_name":"is_a","term_name":"carcinoma in situ of hypopharynx","termid":"MONDO:0021288"},{"relation_name":"is_a","term_name":"carcinoma in situ of oropharynx","termid":"MONDO:0021298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"carcinoma in situ of epiglottis","secondary_identifiers":["SCTID:92584005","icd11.foundation:238950969","UMLS:C0347103","MEDGEN:87571","NCIT:C4592"],"synonyms":[{"name":"Epiglottis carcinoma in situ","type":"exact"},{"name":"carcinoma in situ of epiglottis","type":"exact"},{"name":"carcinoma in situ of the Epiglottis","type":"exact"},{"name":"epiglottic carcinoma in situ","type":"exact"},{"name":"epiglottis carcinoma in situ","type":"exact"},{"name":"epiglottis in situ carcinoma","type":"exact"},{"name":"stage 0 epiglottic carcinoma","type":"exact"},{"name":"stage 0 epiglottic carcinoma aJCC v6","type":"exact"},{"name":"stage 0 epiglottic carcinoma aJCC v6, v7, and v8","type":"exact"},{"name":"stage 0 epiglottic carcinoma aJCC v7","type":"exact"},{"name":"stage 0 epiglottic carcinoma aJCC v8","type":"exact"},{"name":"stage 0 epiglottic throat cancer","type":"exact"},{"name":"stage 0 epiglottis carcinoma","type":"exact"}],"termid":"MONDO:0021287","xrefs":{"Monarch":{"xref_id":"0021287"}}}


id: MONDO:0005661
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Babesiosis refers to a condition caused by microscopic parasites that infect the red blood cells. Many people who are infected with Babesia parasites do not experience any symptoms of the condition. When present, signs and symptoms may include flu-like symptoms such as fever, chills, headache, body aches, nausea and fatigue. In severe cases, babesiosis can be associated with hemolytic anemia. Babesia parasites are primarily spread by infected ticks. Treatment is generally only required in people who develop symptoms of the condition. When necessary, affected people are often prescribed a combination of antimicrobial medications along with supportive care to manage symptoms.","direct_ancestors":[{"relation_name":"is_a","term_name":"protozoa infectious disease","termid":"MONDO:0002428"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"babesiosis","secondary_identifiers":["MEDGEN:2523","icd11.foundation:1947003329","MedDRA:10003965","NCIT:C84581","UMLS:C0004576","MESH:D001404","NORD:832","ICD9:088.82","SCTID:21061004","EFO:0007162","ICD10CM:B60.0","DOID:9643","GARD:5878","Orphanet:108"],"synonyms":[{"name":"Babesia caused disease or disorder","type":"exact"},{"name":"Babesia disease or disorder","type":"exact"},{"name":"Babesia infectious disease","type":"exact"},{"name":"Babesia parasite infection","type":"related"},{"name":"Human babesiosis","type":"related"},{"name":"babesiasis","type":"exact"},{"name":"infection by Babesia","type":"exact"},{"name":"piroplasmosis","type":"exact"}],"termid":"MONDO:0005661","xrefs":{"Monarch":{"xref_id":"0005661"}}}


id: GO:0051264
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.","definition_xrefs":["PMID:15364929","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acylglycerol O-acyltransferase activity","termid":"GO:0016411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016746","GO:0003824","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"mono-olein transacylation activity","synonyms":[{"name":"MOG transacylation","type":"exact"},{"name":"acyl-CoA-independent mono-olein transacylation","type":"exact"},{"name":"mono-oleoylglycerol O-acyltransferase activity","type":"exact"},{"name":"mono-oleoylglycerol transacylase activity","type":"exact"},{"name":"monoolein transacylation","type":"exact"},{"name":"monooleoylglycerol O-acyltransferase activity","type":"exact"},{"name":"monooleoylglycerol transacylase activity","type":"exact"}],"termid":"GO:0051264"}


id: GO:0035143
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"medial fin morphogenesis","termid":"GO:0035141"},{"relation_name":"part_of","term_name":"caudal fin development","termid":"GO:0033336"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"caudal fin morphogenesis","termid":"GO:0035143"}


id: GO:0097138
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.","definition_xrefs":["GOC:so","PMID:14634621"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Bcl-2 family protein complex","termid":"GO:0097136"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"BAD-BCL-2 complex","termid":"GO:0097138"}


id: GO:0048204
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.","definition_xrefs":["GOC:jid","ISBN:0716731363","PMID:10219233","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle targeting, to, from or within Golgi","termid":"GO:0048199"},{"relation_name":"part_of","term_name":"inter-Golgi cisterna vesicle-mediated transport","termid":"GO:0048219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0016192","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"vesicle targeting, inter-Golgi cisterna","synonyms":[{"name":"inter-Golgi cisterna targeting","type":"exact"}],"termid":"GO:0048204"}


id: GO:0003022
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.","definition_xrefs":["ISBN:0323031951","GOC:mtg_cardio"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of hydrogen ion","termid":"GO:0003030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of pH by chemoreceptor signaling","synonyms":[{"name":"detection of pH by chemoreceptor signalling","type":"exact"}],"termid":"GO:0003022"}


id: PBO:0045216
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAJC8 pseudogene 1","termid":"PBO:0045216"}


id: FYPO:0003030
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing via the spliceosome is decreased, where introns have low A/U content and polypyrimidine tracts located approximately 17-19 nt distal to the branch site.","definition_xrefs":["PMID:24298023","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased splicing of mRNA introns with low A/U content","termid":"FYPO:0003242"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0006551","FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0000294"],"is_obsolete":false,"name":"decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site","synonyms":[{"name":"decreased mRNA splicing, via spliceosome, introns with low A/U content and polypyrimidine tracts distal to branch site","type":"exact"},{"name":"decreased nuclear mRNA splicing, via spliceosome, introns with low A/U content and polypyrimidine tracts distal to branch site","type":"exact"},{"name":"decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site","type":"broad"},{"name":"decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site during mitotic cell cycle","type":"related"},{"name":"decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site during vegetative growth","type":"exact"},{"name":"reduced splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site","type":"exact"}],"termid":"FYPO:0003030"}


id: GO:0006789
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin.","definition_xrefs":["DOI:10.1016/0305-0491(80)90243-6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"porphyrin-containing compound catabolic process","termid":"GO:0006787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0033013"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0033013"],"is_obsolete":false,"name":"bilirubin conjugation","termid":"GO:0006789"}


id: PBO:0030952
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K9_acetylation_at_centromere","termid":"PBO:0030952"}


id: PBO:0079129
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TSIX transcript, XIST antisense RNA","termid":"PBO:0079129"}


id: PBO:0086933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles","termid":"PBO:0086933"}


id: PBO:0087226
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Second-largest subunit of RNA polymerase III; RNA polymerase III is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs","termid":"PBO:0087226"}


id: GO:0004161
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = (2E)-geranyl diphosphate + diphosphate.","definition_xrefs":["RHEA:22408"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prenyl diphosphate synthase activity","termid":"GO:0120531"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016765"}],"interesting_parent_ids":["GO:0016765","GO:0016740","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"dimethylallyltranstransferase activity","secondary_identifiers":["Reactome:R-HSA-9717834","Reactome:R-HSA-191322","MetaCyc:GPPSYN-RXN","EC:2.5.1.1"],"synonyms":[{"name":"(2E,6E)-farnesyl diphosphate synthetase activity","type":"related"},{"name":"DMAPP:IPP-dimethylallyltransferase activity","type":"related"},{"name":"dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity","type":"related"},{"name":"dimethylallyltransferase activity","type":"exact"},{"name":"diprenyltransferase activity","type":"related"},{"name":"geranyl diphosphate synthase activity","type":"exact"},{"name":"geranyl pyrophosphate synthase activity","type":"related"},{"name":"geranyl pyrophosphate synthetase activity","type":"related"},{"name":"geranyl-diphosphate synthase activity","type":"related"},{"name":"trans-farnesyl pyrophosphate synthetase activity","type":"related"}],"termid":"GO:0004161"}


id: PBO:0041063
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BRF1 RNA polymerase III transcription initiation factor subunit","termid":"PBO:0041063"}


id: PBO:0053086
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"late cornified envelope 1D","termid":"PBO:0053086"}


id: FYPO:0003474
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which nucleus is broken into multiple small fragments that are smaller than a normal nucleus, hen the cell is subject to salt stress.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fragmented nucleus during vegetative growth","termid":"FYPO:0001919"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002403"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002403","FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"fragmented nucleus during cellular response to salt stress","synonyms":[{"name":"fragmented nuclear DNA during cellular response to salt stress","type":"related"},{"name":"fragmented nucleus during cellular response to salt stress during mitotic cell cycle","type":"related"},{"name":"fragmented nucleus during cellular response to salt stress during vegetative growth","type":"exact"},{"name":"loss of nuclear integrity during cellular response to salt stress","type":"related"}],"termid":"FYPO:0003474"}


id: FYPO:0001411
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell differs from normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered level of substance in cell during vegetative growth","termid":"FYPO:0001323"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"altered cellular sulfide level","synonyms":[{"name":"abnormal cellular sulfide accumulation","type":"related"},{"name":"abnormal cellular sulfide level","type":"exact"},{"name":"altered cellular acid labile sulfide level","type":"exact"},{"name":"altered cellular sulfide ion level","type":"exact"},{"name":"altered cellular sulfide level during mitotic cell cycle","type":"related"},{"name":"altered cellular sulfide level during vegetative growth","type":"exact"},{"name":"altered cellular sulphide level","type":"exact"}],"termid":"FYPO:0001411"}


id: GO:0043354
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"erythrocyte maturation","termid":"GO:0043249"},{"relation_name":"part_of","term_name":"enucleate erythrocyte development","termid":"GO:0048822"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"enucleate erythrocyte maturation","synonyms":[{"name":"enucleate RBC maturation","type":"exact"},{"name":"enucleate red blood cell maturation","type":"exact"}],"termid":"GO:0043354"}


id: PBO:0076393
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptional adaptor 1","termid":"PBO:0076393"}


id: FYPO:0007449
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished, and some of the protein is present in the cytoplasm instead.","definition_xrefs":["PMID:32735772","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein mislocalized to cytoplasm during vegetative growth","termid":"FYPO:0000783"},{"relation_name":"is_a","term_name":"abnormal protein localization to endoplasmic reticulum during vegetative growth","termid":"FYPO:0003777"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000138","FYPO:0001320","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm","synonyms":[{"name":"abolished protein localization to ER, with protein mislocalized to cytoplasm","type":"exact"},{"name":"abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm during vegetative growth","type":"exact"}],"termid":"FYPO:0007449"}


id: PBO:0049818
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HDAC9 antisense RNA 1","termid":"PBO:0049818"}


id: MONDO:0005272
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A myelodysplastic syndrome characterized by dysplasia seen in at least 10% of the early cells of 1 cell type (either red blood cells, white blood cells, or megakaryocytes) in the bone marrow.","definition_xrefs":["doi:10.5772/intechopen.82532"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"myelodysplastic syndrome with multilineage dysplasia","termid":"MONDO:0019453"},{"relation_name":"is_a","term_name":"myelodysplastic syndrome","termid":"MONDO:0018881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"myelodysplastic syndrome with single lineage dysplasia","secondary_identifiers":["ICD9:238.72","MedDRA:10038269","GARD:19585","EFO:0003802","icd11.foundation:149518956","MEDGEN:415300","MESH:D000753","NCIT:C2872","NCIT:C82591","Orphanet:98826","SCTID:109996008","SCTID:1153345005","UMLS:C2826318","ICDO:9980/3"],"synonyms":[{"name":"MDS with single lineage dysplasia","type":"exact"},{"name":"MDS-SLD","type":"exact"},{"name":"RA","type":"exact"},{"name":"aregenerative anaemia","type":"related"},{"name":"aregenerative anemia","type":"related"},{"name":"refractory anaemia","type":"exact"},{"name":"refractory anemia","type":"exact"}],"termid":"MONDO:0005272","xrefs":{"Monarch":{"xref_id":"0005272"}}}


id: GO:0005528
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a 23-membered macrolide lactone FK506.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"macrolide binding","termid":"GO:0005527"},{"relation_name":"is_a","term_name":"amide binding","termid":"GO:0033218"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"FK506 binding","synonyms":[{"name":"FK506-sensitive peptidyl-prolyl cis-trans isomerase","type":"related"}],"termid":"GO:0005528"}


id: GO:0072461
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.","definition_xrefs":["GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to meiotic cell cycle checkpoint signaling","termid":"GO:0072410"},{"relation_name":"is_a","term_name":"meiotic cell cycle process","termid":"GO:1903046"},{"relation_name":"part_of","term_name":"meiotic recombination checkpoint signaling","termid":"GO:0051598"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0023052"],"is_obsolete":false,"name":"response to meiotic recombination checkpoint signaling","synonyms":[{"name":"meiotic recombination checkpoint effector process","type":"exact"},{"name":"response to signal involved in meiotic recombination checkpoint","type":"exact"}],"termid":"GO:0072461"}


id: PBO:0110326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ALDOC antisense RNA 1","termid":"PBO:0110326"}


id: MONDO:0004936
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A complication of obstetric labor in which the corpus of the uterus is forced completely or partially through the uterine cervix. This can occur during the late stages of labor and is associated with immediate postpartum hemorrhage.","definition_xrefs":["MESH:D019687"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uterine disorder","termid":"MONDO:0002654"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uterine inversion","secondary_identifiers":["DOID:997","UMLS:C0162482","ICD9:665.2","SCTID:27215002","MEDGEN:57916"],"termid":"MONDO:0004936","xrefs":{"Monarch":{"xref_id":"0004936"}}}


id: PBO:0087076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L37B; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; protein abundance increases in response to DNA replication stress; homologous to mammalian ribosomal protein L37, no bacterial homolog; RPL37B has a paralog, RPL37A, that arose from the whole genome duplication","termid":"PBO:0087076"}


id: FYPO:0006003
data:
  {"alleles_by_uniquename":{"SJAG_04883:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04883","name":"ptp4delta","uniquename":"SJAG_04883:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[118676],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0001007"}]},"cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which any process of cellular component organization at the cellular level is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah","GO:0016043"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component organization phenotype","termid":"FYPO:0000334"},{"relation_name":"is_a","term_name":"normal cellular process","termid":"FYPO:0000627"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04883":null},"genotype_count":1,"genotypes_by_uniquename":{"ptp4delta":{"display_name":"ptp4delta","display_uniquename":"ptp4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04883:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal cellular component organization","references_by_uniquename":{"PMID:36695178":null},"single_locus_annotated_genes":["SJAG_04883"],"single_locus_genotype_uniquenames":["ptp4delta"],"synonyms":[{"name":"normal cellular component organisation","type":"exact"},{"name":"normal cellular component organization at cellular level","type":"exact"}],"termid":"FYPO:0006003","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000137":null,"FYPO:0001007":null}}


id: FYPO:0001121
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which cell shape is altered, but cell size remains normal, in the vegetative growth phase of the life cycle.","definition_xrefs":["PomBase:vw","PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"normal vegetative cell size","termid":"FYPO:0001124"},{"relation_name":"has_part","term_name":"abnormal cell shape","termid":"FYPO:0001126"},{"relation_name":"is_a","term_name":"normal vegetative cell size","termid":"FYPO:0001124"},{"relation_name":"is_a","term_name":"abnormal vegetative cell shape","termid":"FYPO:0002196"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001312","FYPO:0000005","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"vegetative cell, abnormal cell shape, normal cell size","synonyms":[{"name":"abnormal cell shape, normal cell size during vegetative growth","type":"exact"},{"name":"lumpy","type":"related"},{"name":"vegetative cell, abnormal cell shape, normal cell length","type":"narrow"},{"name":"vegetative cell, abnormal cell shape, normal cell size during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001121"}


id: PBO:0028522
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_zearalenone","termid":"PBO:0028522"}


id: PBO:0067168
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 221, pseudogene","termid":"PBO:0067168"}


id: PBO:0072840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SAP30L antisense RNA 1 (head to head)","termid":"PBO:0072840"}


id: PBO:0055212
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2637","termid":"PBO:0055212"}


id: PBO:0040924
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"basonuclin 2","termid":"PBO:0040924"}


id: GO:1990216
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont initiates, promotes, or enhances transcription of genes into mRNA in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:21994350"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host transcription","termid":"GO:0052026"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated activation of host transcription","synonyms":[{"name":"positive regulation by symbiont of host transcription","type":"exact"}],"termid":"GO:1990216"}


id: MONDO:0007617
data:
  {"annotated_genes":["SJAG_02254"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85509],"is_not":false,"summary":null,"term":"MONDO:0007617"}]},"cv_name":"mondo","definition":"Any Coffin-Siris syndrome in which the cause of the disease is a mutation in the ARID1B gene.","definition_xrefs":["MONDO:patterns/OMIM_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"autosomal dominant non-syndromic intellectual disability","termid":"MONDO:0015802"},{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"Coffin-Siris syndrome","termid":"MONDO:0015452"},{"relation_name":"is_a","term_name":"BAFopathy","termid":"MONDO:0700120"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02254":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"Coffin-Siris syndrome 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:614562","UMLS:C3281201","MEDGEN:482831","OMIM:135900","GARD:15072","MESH:C538391","OMIM:609943","DOID:0070042"],"synonyms":[{"name":"ARID1B-related BAFopathy","type":"exact"},{"name":"COFFIN-SIRIS syndrome","type":"related"},{"name":"COFFIN-SIRIS syndrome 1","type":"exact"},{"name":"CSS","type":"related"},{"name":"CSS1","type":"exact"},{"name":"Coffin-Siris syndrome 1","type":"exact"},{"name":"MRD12","type":"exact"},{"name":"autosomal dominant mental retardation 12","type":"exact"},{"name":"fifth digit syndrome","type":"broad"},{"name":"hypertrichosis, hyperkeratosis, intellectual disability, and distinctive facial features","type":"exact"},{"name":"hypertrichosis, hyperkeratosis, mental retardation, and distinctive facial features","type":"exact"},{"name":"intellectual disability, autosomal dominant 12","type":"exact"},{"name":"mental retardation, autosomal dominant 12","type":"related"},{"name":"mental retardation, autosomal dominant type 12","type":"exact"}],"termid":"MONDO:0007617","terms_by_termid":{"MONDO:0007617":null},"xrefs":{"Monarch":{"xref_id":"0007617"}}}


id: GO:0099192
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell.","definition_xrefs":["PMID:26134650"],"direct_ancestors":[{"relation_name":"is_a","term_name":"synapse","termid":"GO:0045202"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"cerebellar Golgi cell to granule cell synapse","termid":"GO:0099192"}


id: GO:0005227
data:
  {"annotated_genes":["SJAG_03895","SJAG_02322"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[95487,108831],"is_not":false,"summary":null,"term":"GO:0005227"}]},"cv_name":"molecular_function","definition":"Enables the transmembrane transfer of an inorganic cation by a channel that opens when a calcium cation has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["GOC:dph","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monoatomic ion-gated channel activity","termid":"GO:0022839"},{"relation_name":"is_a","term_name":"ligand-gated monoatomic cation channel activity","termid":"GO:0099094"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02322":null,"SJAG_03895":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"calcium-activated cation channel activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-9717383"],"synonyms":[{"name":"calcium activated cation channel activity","type":"exact"},{"name":"intracellular calcium-activated potassium channel","type":"narrow"},{"name":"polycystin","type":"narrow"}],"termid":"GO:0005227","terms_by_termid":{"GO:0005227":null}}


id: MONDO:0011056
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary Wilms tumor","termid":"MONDO:0003321"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005240"],"is_obsolete":false,"name":"Wilms tumor 4","secondary_identifiers":["UMLS:C1832426","MEDGEN:318623","OMIM:601363","MESH:C563336","GARD:15328"],"synonyms":[{"name":"WT4","type":"related"},{"name":"Wilms tumor 4","type":"exact"},{"name":"Wilms tumor type 4","type":"exact"},{"name":"Wilms tumor, type 4","type":"exact"},{"name":"Wilms tumour type 4","type":"exact"},{"name":"familial Wilms tumor 1","type":"related"},{"name":"familial Wilms tumour 1","type":"related"}],"termid":"MONDO:0011056","xrefs":{"Monarch":{"xref_id":"0011056"}}}


id: MONDO:0015937
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare inflammatory eye disease (obsolete MONDO:0015937)","secondary_identifiers":["Orphanet:182214"],"termid":"MONDO:0015937","xrefs":{"Monarch":{"xref_id":"0015937"}}}


id: PBO:0016966
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kinesin Like Protein","termid":"PBO:0016966"}


id: PBO:0086182
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation","termid":"PBO:0086182"}


id: MONDO:1012674
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any centronuclear myopathy that occurs in dogs due to a mutation in the HACD1 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital myopathy, dog","termid":"MONDO:1010918"},{"relation_name":"is_a","term_name":"centronuclear myopathy, non-human animal","termid":"MONDO:1012963"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centronuclear myopathy, HACD1-related, dog","secondary_identifiers":["OMIA:001374-9615"],"synonyms":[{"name":"HMLR","type":"exact"},{"name":"autosomal recessive muscular dystrophy","type":"related"},{"name":"hereditary myopathy of Labrador retrievers","type":"narrow"}],"termid":"MONDO:1012674","xrefs":{"Monarch":{"xref_id":"1012674"}}}


id: PBO:0053096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"late cornified envelope 3D","termid":"PBO:0053096"}


id: GO:0033748
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2 + A = AH2.","definition_xrefs":["EC:1.12.99.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on hydrogen as donor","termid":"GO:0016695"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"hydrogenase (acceptor) activity","secondary_identifiers":["MetaCyc:RXN0-4141","RHEA:12116"],"synonyms":[{"name":"H2 producing hydrogenase activity","type":"broad"},{"name":"hydrogen-lyase activity","type":"broad"},{"name":"hydrogen:(acceptor) oxidoreductase activity","type":"related"},{"name":"hydrogen:acceptor oxidoreductase activity","type":"related"},{"name":"hydrogenlyase activity","type":"broad"},{"name":"uptake hydrogenase activity","type":"broad"}],"termid":"GO:0033748"}


id: PR:Q10202
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dbp3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10202"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase dbp3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC17D1.06","synonyms":[{"name":"Spom972h-dbp3","type":"exact"}],"termid":"PR:Q10202"}


id: GO:0048047
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner.","definition_xrefs":["PMID:12486700","GOC:jid","GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mating behavior","termid":"GO:0007617"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mating behavior, sex discrimination","synonyms":[{"name":"mating behaviour, sex discrimination","type":"exact"}],"termid":"GO:0048047"}


id: GO:0019817
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle fusion","termid":"GO:0006906"},{"relation_name":"is_a","term_name":"peroxisome organization","termid":"GO:0007031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0007031"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0008150","GO:0061024","GO:0006810","GO:0007031","GO:0016192"],"is_obsolete":false,"name":"vesicle fusion with peroxisome","termid":"GO:0019817"}


id: GO:0002946
data:
  {"annotated_genes":["SJAG_00325","SJAG_01314","SJAG_02099","SJAG_05249"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89970,105249],"is_not":false,"summary":null,"term":"GO:0002946"},{"annotations":[93431,87779],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002127"}]},"cv_name":"biological_process","definition":"The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.","definition_xrefs":["ISBN:155581073X"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA methylation","termid":"GO:0030488"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00325":null,"SJAG_01314":null,"SJAG_02099":null,"SJAG_05249":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0006399"}],"interesting_parent_ids":["GO:0006399","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"tRNA C5-cytosine methylation","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"tRNA 5-methylcytosine biosynthesis","type":"related"}],"termid":"GO:0002946","terms_by_termid":{"GO:0002127":null,"GO:0002946":null}}


id: GO:0050921
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of response to external stimulus","termid":"GO:0032103"},{"relation_name":"is_a","term_name":"positive regulation of locomotion","termid":"GO:0040017"},{"relation_name":"is_a","term_name":"regulation of chemotaxis","termid":"GO:0050920"},{"relation_name":"positively_regulates","term_name":"chemotaxis","termid":"GO:0006935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of chemotaxis","synonyms":[{"name":"activation of chemotaxis","type":"narrow"},{"name":"stimulation of chemotaxis","type":"narrow"},{"name":"up regulation of chemotaxis","type":"exact"},{"name":"up-regulation of chemotaxis","type":"exact"},{"name":"upregulation of chemotaxis","type":"exact"}],"termid":"GO:0050921"}


id: GO:0032871
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of nucleus organization","termid":"GO:1903353"},{"relation_name":"regulates","term_name":"karyogamy","termid":"GO:0000741"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of karyogamy","termid":"GO:0032871"}


id: MONDO:0005920
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Malaria resulting from infection by Plasmodium falciparum.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"malaria","termid":"MONDO:0005136"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"Plasmodium falciparum malaria","secondary_identifiers":["DOID:14067","EFO:0007444","SCTID:62676009","NCIT:C34798","ICD9:084.0","ICD9:084.9","MESH:D016778","UMLS:C0024535","MEDGEN:6185"],"synonyms":[{"name":"Plasmodium falciparum malaria, unspecified","type":"exact"},{"name":"falciparum malaria","type":"exact"},{"name":"falciparum malaria [malignant tertian]","type":"exact"},{"name":"malaria fever, subtertian","type":"exact"},{"name":"malignant tertian fever","type":"exact"},{"name":"malignant tertian fever (finding)","type":"exact"}],"termid":"MONDO:0005920","xrefs":{"Monarch":{"xref_id":"0005920"}}}


id: PBO:0045476
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aspartate rich 1","termid":"PBO:0045476"}


id: PBO:0012583
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G Protein Beta gene","termid":"PBO:0012583"}


id: PBO:0082743
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p","termid":"PBO:0082743"}


id: MONDO:0014472
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary periodic fever syndrome","termid":"MONDO:0017953"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"periodic fever-infantile enterocolitis-autoinflammatory syndrome","secondary_identifiers":["NORD:1939","GARD:17725","MEDGEN:863504","NANDO:1200994","OMIM:616050","NANDO:2200459","UMLS:C4015067","Orphanet:436166"],"synonyms":[{"name":"AIFEC","type":"related"},{"name":"AUTOINFLAMMATION with infantile enterocolitis","type":"related"},{"name":"Autoinflammation with Infantile Enterocolitis","type":"exact"},{"name":"NLRC4-related MAS","type":"exact"},{"name":"NLRC4-related autoinflammatory syndrome with MAS","type":"exact"},{"name":"NLRC4-related autoinflammatory syndrome with macrophage activation syndrome","type":"exact"},{"name":"NLRC4-related infantile enterocolitis-autoinflammatory syndrome","type":"exact"},{"name":"NLRC4-related macrophage activation syndrome","type":"exact"},{"name":"autoinflammation with infantile enterocolitis","type":"exact"}],"termid":"MONDO:0014472","xrefs":{"Monarch":{"xref_id":"0014472"}}}


id: PBO:0083496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL194W/CDC6","termid":"PBO:0083496"}


id: GO:0007601
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory perception of light stimulus","termid":"GO:0050953"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"visual perception","secondary_identifiers":["Wikipedia:Visual_perception"],"synonyms":[{"name":"sense of sight","type":"exact"},{"name":"sensory visual perception","type":"exact"},{"name":"vision","type":"exact"}],"termid":"GO:0007601"}


id: PR:O59718
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- nem1 gene.","definition_xrefs":["UniProtKB:O59718","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear envelope morphology protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC3B8.10c","synonyms":[{"name":"Spom972h-nem1","type":"exact"}],"termid":"PR:O59718"}


id: PBO:0001294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial cytochrome c-heme linkage protein Cyc2 (predicted)","termid":"PBO:0001294"}


id: GO:0032286
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myelin maintenance","termid":"GO:0043217"},{"relation_name":"part_of","term_name":"central nervous system myelination","termid":"GO:0022010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0061024"],"is_obsolete":false,"name":"central nervous system myelin maintenance","synonyms":[{"name":"central nervous system myelin sheath maintenance","type":"exact"},{"name":"myelin maintenance in central nervous system","type":"exact"}],"termid":"GO:0032286"}


id: PBO:0091609
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"helper of TIM Hot13","termid":"PBO:0091609"}


id: GO:0060475
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction.","definition_xrefs":["GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of actin filament polymerization involved in acrosome reaction (obsolete GO:0060475)","synonyms":[{"name":"positive regulation of actin polymerization involved in acrosome reaction","type":"related"}],"termid":"GO:0060475"}


id: GO:0080152
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle.","definition_xrefs":["PMID:17031544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of photosynthesis, dark reaction","termid":"GO:0010110"},{"relation_name":"regulates","term_name":"reductive pentose-phosphate cycle","termid":"GO:0019253"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"regulation of reductive pentose-phosphate cycle","synonyms":[{"name":"regulation of C3 photosynthesis","type":"narrow"},{"name":"regulation of Calvin cycle","type":"narrow"}],"termid":"GO:0080152"}


id: PBO:0063360
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostate cancer expressed EZH2 associated transcript","termid":"PBO:0063360"}


id: PBO:0074629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 24B","termid":"PBO:0074629"}


id: PBO:0017602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTP cyclohydrolase Rib1 (predicted)","termid":"PBO:0017602"}


id: GO:0090550
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum.","definition_xrefs":["GOC:tair_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to starvation","termid":"GO:0042594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to molybdenum starvation","termid":"GO:0090550"}


id: PBO:0028351
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_CENP-A_containing_chromatin_organization","termid":"PBO:0028351"}


id: MONDO:0005175
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Insulitis is an inflammatory infiltration of the islets of Langerhans found especially in young patients with recent onset type 1 diabetes.","definition_xrefs":["EFO:0002498"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endocrine pancreas disorder","termid":"MONDO:0001933"},{"relation_name":"is_a","term_name":"immune system disorder","termid":"MONDO:0005046"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0005046"],"is_obsolete":false,"name":"aggressive insulitis","termid":"MONDO:0005175","xrefs":{"Monarch":{"xref_id":"0005175"}}}


id: MONDO:0021043
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm composed of at least two distinct cellular populations.","definition_xrefs":["NCIT:C6930"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm","termid":"MONDO:0005070"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mixed neoplasm","secondary_identifiers":["ICDO:8940/1","MESH:D018193","UMLS:C1368354","MEDGEN:234575"],"synonyms":[{"name":"mixed neoplasm","type":"exact"},{"name":"mixed tumor","type":"exact"},{"name":"mixed tumour","type":"exact"}],"termid":"MONDO:0021043","xrefs":{"Monarch":{"xref_id":"0021043"}}}


id: MONDO:0020792
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dwarfism with tall vertebrae","secondary_identifiers":["MESH:C535725","OMIM:126950","UMLS:C1851996","MEDGEN:338839"],"termid":"MONDO:0020792","xrefs":{"Monarch":{"xref_id":"0020792"}}}


id: MONDO:0012512
data:
  {"annotated_genes":["SJAG_05271"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85502],"is_not":false,"summary":null,"term":"MONDO:0012512"}]},"cv_name":"mondo","definition":"Combined oxidative phosphorylation deficiency type 3 is an extremely rare clinically heterogenous disorder described in about 5 patients to date. Clinical signs included hypotonia, lactic acidosis, and hepatic insufficiency, with progressive encephalomyopathy or hypertrophic cardiomyopathy.","definition_xrefs":["Orphanet:168566"],"direct_ancestors":[{"relation_name":"is_a","term_name":"combined oxidative phosphorylation deficiency","termid":"MONDO:0000732"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05271":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:720951008","UMLS:C1864840","MEDGEN:355842","MESH:C566467","DOID:0111486","GARD:17035","OMIM:610505"],"synonyms":[{"name":"COXPD3","type":"related"},{"name":"TSFM combined oxidative phosphorylation deficiency","type":"exact"},{"name":"combined oxidative phosphorylation deficiency 3","type":"related"},{"name":"combined oxidative phosphorylation deficiency caused by mutation in TSFM","type":"exact"},{"name":"combined oxidative phosphorylation deficiency type 3","type":"exact"},{"name":"concentric cardiomyopathy, hypotonia, and lactic acidosis","type":"related"},{"name":"encephalomyopathy, respiratory failure, and lactic acidosis","type":"related"},{"name":"fatal mitochondrial disease due to COXPD3","type":"exact"}],"termid":"MONDO:0012512","terms_by_termid":{"MONDO:0012512":null},"xrefs":{"Monarch":{"xref_id":"0012512"}}}


id: GO:0005328
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).","definition_xrefs":["TC:2.A.22.-.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurotransmitter transmembrane transporter activity","termid":"GO:0005326"},{"relation_name":"is_a","term_name":"solute:sodium symporter activity","termid":"GO:0015370"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"neurotransmitter:sodium symporter activity","synonyms":[{"name":"sodium/neurotransmitter symporter activity","type":"exact"}],"termid":"GO:0005328"}


id: PBO:0069703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 983, pseudogene","termid":"PBO:0069703"}


id: PBO:0080207
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vestigial like family member 1","termid":"PBO:0080207"}


id: MONDO:0800156
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder of amino acid metabolism that has its basis in the disruption of the metabolism of ornithine, proline and/or hydroxyproline.","definition_xrefs":["MONDO:patterns/inborn_metabolic"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of amino acid metabolism","termid":"MONDO:0004736"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"inborn disorder of ornithine, proline and hydroxyproline metabolism","termid":"MONDO:0800156","xrefs":{"Monarch":{"xref_id":"0800156"}}}


id: PBO:0076685
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TCEAL3 antisense RNA 1","termid":"PBO:0076685"}


id: PBO:0031486
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-short_meiotic_spindle","termid":"PBO:0031486"}


id: PR:P87142
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ssz1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P87142"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein 70 homolog C57A7.12 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC57A7.12","synonyms":[{"name":"Spom972h-ssz1","type":"exact"}],"termid":"PR:P87142"}


id: GO:0005765
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lytic vacuole membrane","termid":"GO:0098852"},{"relation_name":"part_of","term_name":"lysosome","termid":"GO:0005764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005773"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005773","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"lysosomal membrane","synonyms":[{"name":"lysosome membrane","type":"exact"}],"termid":"GO:0005765"}


id: GO:0009666
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid.","definition_xrefs":["GOC:jl","GOC:dph","GOC:mah","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plastid membrane organization","termid":"GO:0009668"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0061024"],"is_obsolete":false,"name":"plastid outer membrane organization","synonyms":[{"name":"plastid outer membrane organisation","type":"exact"},{"name":"plastid outer membrane organization and biogenesis","type":"related"}],"termid":"GO:0009666"}


id: MONDO:0019006
data:
  {"annotated_genes":["SJAG_04621","SJAG_00933","SJAG_03361","SJAG_01185","SJAG_00093","SJAG_04148","SJAG_04000","SJAG_03182"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85825],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013836"},{"annotations":[84625],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011303"},{"annotations":[85432],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014752"},{"annotations":[85356,85357],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014817"},{"annotations":[85355],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014818"},{"annotations":[84542],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014099"},{"annotations":[85361],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014257"}]},"cv_name":"mondo","definition":"Familial idiopathic steroid-resistant nephrotic syndrome is characterized by a nephrotic syndrome with often early onset.","definition_xrefs":["Orphanet:656"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial nephrotic syndrome","termid":"MONDO:0002350"},{"relation_name":"is_a","term_name":"idiopathic nephrotic syndrome","termid":"MONDO:0018170"},{"relation_name":"is_a","term_name":"steroid-resistant nephrotic syndrome","termid":"MONDO:0044765"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00093":null,"SJAG_00933":null,"SJAG_01185":null,"SJAG_03182":null,"SJAG_03361":null,"SJAG_04000":null,"SJAG_04148":null,"SJAG_04621":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"familial idiopathic steroid-resistant nephrotic syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:718141008","GARD:3946","icd11.foundation:1385860879","UMLS:C4273714","MEDGEN:902527"],"synonyms":[{"name":"familial idiopathic nephrotic syndrome","type":"exact"}],"termid":"MONDO:0019006","terms_by_termid":{"MONDO:0011303":null,"MONDO:0013836":null,"MONDO:0014099":null,"MONDO:0014257":null,"MONDO:0014752":null,"MONDO:0014817":null,"MONDO:0014818":null},"xrefs":{"Monarch":{"xref_id":"0019006"}}}


id: PBO:0085756
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase","termid":"PBO:0085756"}


id: GO:1903260
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location within a mating projection tip.","definition_xrefs":["PMID:11952834","GO_REF:0000087","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to cell tip","termid":"GO:1990151"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to mating projection tip","synonyms":[{"name":"protein localisation in mating projection tip","type":"exact"},{"name":"protein localisation to mating projection tip","type":"exact"},{"name":"protein localization in mating projection tip","type":"exact"},{"name":"protein localization to conjugation tube tip","type":"narrow"},{"name":"protein localization to shmoo tip","type":"narrow"}],"termid":"GO:1903260"}


id: FYPO:0002471
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to ionizing radiation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein phosphorylation during vegetative growth","termid":"FYPO:0002033"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002274","FYPO:0000002","FYPO:0001320","FYPO:0002494","FYPO:0001985"],"is_obsolete":false,"name":"abolished protein phosphorylation during cellular response to ionizing radiation","synonyms":[{"name":"abolished protein phosphorylation during cellular response to IR","type":"exact"},{"name":"abolished protein phosphorylation during cellular response to ionizing radiation during mitotic cell cycle","type":"related"},{"name":"abolished protein phosphorylation during cellular response to ionizing radiation during vegetative growth","type":"exact"},{"name":"protein phosphorylation abolished during cellular response to ionizing radiation","type":"exact"}],"termid":"FYPO:0002471"}


id: MONDO:0020434
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"atrial septal defect","termid":"MONDO:0006664"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"atrial septal defect, ostium secundum type","secondary_identifiers":["MEDGEN:91034","GARD:5865","NANDO:2200266","MedDRA:10031302","MedDRA:10031303","icd11.foundation:1875768490","UMLS:C0344724","Orphanet:99103"],"synonyms":[{"name":"ASD ostium secundum type","type":"related"},{"name":"ASD, ostium secundum type","type":"exact"},{"name":"osASD","type":"related"},{"name":"ostium secundum ASD","type":"related"},{"name":"ostium secundum atrial septal defect","type":"related"}],"termid":"MONDO:0020434","xrefs":{"Monarch":{"xref_id":"0020434"}}}


id: PBO:0029741
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-spheroid_cell_during_nitrogen_starvation","termid":"PBO:0029741"}


id: MONDO:0017411
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neonatal inflammatory skin and bowel disease is a rare, life-threatening, autoinflammatory syndrome with immune deficiency disorder characterized by early-onset, life-long inflammation, affecting the skin and bowel, associated with recurrent infections. Patients present perioral and perianal psoriasiform erythema and papular eruption with pustules, failure to thrive associated with chronic malabsorptive diarrhea, intercurrent gastrointestinal infections and feeding troubles, as well as absent, short or broken hair and trichomegaly. Recurrent cutaneous and pulmonary infections lead to recurrent blepharitis, otitis externa and bronchiolitis.","definition_xrefs":["Orphanet:294023"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inflammatory bowel disease","termid":"MONDO:0005265"},{"relation_name":"is_a","term_name":"epidermal disease","termid":"MONDO:0019268"},{"relation_name":"is_a","term_name":"autoinflammatory syndrome","termid":"MONDO:0019751"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005093","MONDO:0004335"],"is_obsolete":false,"name":"neonatal inflammatory skin and bowel disease","secondary_identifiers":["GARD:17355","MEDGEN:1648296","OMIMPS:614328","UMLS:C4751120"],"synonyms":[{"name":"inflammatory skin and bowel disease, neonatal","type":"exact"}],"termid":"MONDO:0017411","xrefs":{"Monarch":{"xref_id":"0017411"}}}


id: PBO:0082651
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of Shu complex (aka PCSS complex); Shu complex also includes Psy3, Csm2, Shu2, and promotes error-free DNA repair, mediates inhibition of Srs2p function; essential for promoting the establishment of homolog bias during meiotic homologous recombination; promotes both crossover (CO) and non-crossover (NCO) pathways of meiotic recombination and formation of Rad51p filaments","termid":"PBO:0082651"}


id: PBO:0064103
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi like RNA-mediated gene silencing 4","termid":"PBO:0064103"}


id: GO:0048501
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane.","definition_xrefs":["GOC:mlg","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signal recognition particle","termid":"GO:0048500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"signal recognition particle, plasma membrane targeting","termid":"GO:0048501"}


id: MONDO:0009345
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Histidinemia is a rare metabolic disorder characterized by elevated histidine levels in blood, urine, and cerebrospinal fluid, generally with no clinical repercussions.","definition_xrefs":["Orphanet:2157"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of histidine metabolism","termid":"MONDO:0019228"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"histidinemia","secondary_identifiers":["GARD:6661","MESH:C538320","icd11.foundation:261052955","OMIM:235800","NORD:1245","SCTID:410058007","DOID:0060168","UMLS:C0220992","MEDGEN:113135","ICD10CM:E70.41"],"synonyms":[{"name":"HIS deficiency","type":"exact"},{"name":"Hal deficiency","type":"exact"},{"name":"Histidinuria","type":"exact"},{"name":"histidase deficiency","type":"exact"},{"name":"histidine ammonia-lyase deficiency","type":"exact"},{"name":"histidinemia","type":"exact"},{"name":"histidinuria","type":"exact"},{"name":"hyperhistidinemia","type":"exact"}],"termid":"MONDO:0009345","xrefs":{"Monarch":{"xref_id":"0009345"}}}


id: GO:1903318
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.","definition_xrefs":["GOC:TermGenie","GOC:vw","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of gene expression","termid":"GO:0010629"},{"relation_name":"is_a","term_name":"negative regulation of protein metabolic process","termid":"GO:0051248"},{"relation_name":"is_a","term_name":"regulation of protein maturation","termid":"GO:1903317"},{"relation_name":"negatively_regulates","term_name":"protein maturation","termid":"GO:0051604"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0051604"},{"rel_name":"regulates","termid":"GO:0051604"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0051604"],"is_obsolete":false,"name":"negative regulation of protein maturation","synonyms":[{"name":"down regulation of protein maturation","type":"exact"},{"name":"down-regulation of protein maturation","type":"exact"},{"name":"downregulation of protein maturation","type":"exact"},{"name":"inhibition of protein maturation","type":"narrow"}],"termid":"GO:1903318"}


id: PBO:0002700
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"possibly related to human/mouse periphilin","termid":"PBO:0002700"}


id: PBO:0049936
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HHIP like 2","termid":"PBO:0049936"}


id: MONDO:0009504
data:
  {"annotated_genes":["SJAG_01524"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86746],"is_not":false,"summary":null,"term":"MONDO:0009504"}]},"cv_name":"mondo","definition":"Fatal infantile lactic acidosis with methylmalonic aciduria is a rare neurometabolic disease characterized by infantile onset of severe encephalomyopathy, lactic acidosis and elevated methylmalonic acid urinary excretion. Clinically it manifests with severe psychomotor delay, hypotonia, failure to thrive, feeding difficulties and dystonia. Epilepsy and multiple congenital anomalies may be associated.","definition_xrefs":["Orphanet:17"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lactic acidosis","termid":"MONDO:0006040"},{"relation_name":"is_a","term_name":"mitochondrial DNA depletion syndrome, encephalomyopathic form","termid":"MONDO:0016796"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01524":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"mitochondrial DNA depletion syndrome 9","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:3163","SCTID:715338007","OMIM:245400","UMLS:C3151476","MESH:C538134","DOID:0080128","MESH:C566885","MEDGEN:462826"],"synonyms":[{"name":"MTDPS9","type":"related"},{"name":"SUCLG1 mitochondrial DNA depletion syndrome","type":"exact"},{"name":"fatal infantile lactic acidosis with methylmalonic aciduria","type":"related"},{"name":"lactic acidosis congenital infantile","type":"related"},{"name":"lactic acidosis, fatal infantile","type":"related"},{"name":"lactic acidosis, fatal infantile, formerly","type":"related"},{"name":"mitochondrial DNA depletion syndrome 9","type":"exact"},{"name":"mitochondrial DNA depletion syndrome 9 (encephalomyopathic type with methylmalonic aciduria)","type":"related"},{"name":"mitochondrial DNA depletion syndrome caused by mutation in SUCLG1","type":"exact"},{"name":"mitochondrial DNA depletion syndrome type 9","type":"exact"},{"name":"succinate-CoA ligase deficiency","type":"broad"}],"termid":"MONDO:0009504","terms_by_termid":{"MONDO:0009504":null},"xrefs":{"Monarch":{"xref_id":"0009504"}}}


id: GO:0032978
data:
  {"annotated_genes":["SJAG_05300","SJAG_05302","SJAG_01405","SJAG_03633","SJAG_01917"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[98510,112790,100407,88315,114140],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032979"}]},"cv_name":"biological_process","definition":"The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.","definition_xrefs":["PMID:14739936","PMID:15473843"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein insertion into membrane","termid":"GO:0051205"}],"gene_count":5,"genes_by_uniquename":{"SJAG_01405":null,"SJAG_01917":null,"SJAG_03633":null,"SJAG_05300":null,"SJAG_05302":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0061024","GO:0008150"],"is_obsolete":false,"name":"protein insertion into membrane from inner side","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"insertion of proteins into membrane from the inner side","type":"exact"}],"termid":"GO:0032978","terms_by_termid":{"GO:0032979":null}}


id: SO:0001152
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A type VIa beta turn with the following phi and psi sngles on amino acid residues 2 and 3: phi-2 = -60 degrees, psi-2 = 120 degrees, phi-3 = -90 degrees, psi-3 = 0 degrees.","definition_xrefs":["PMID:27428516"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta_turn_type_six_a","termid":"SO:0001151"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"beta_turn_type_six_a_one","synonyms":[{"name":"beta turn type six a one","type":"exact"},{"name":"type VIa1 beta turn","type":"exact"},{"name":"type VIa1 turn","type":"exact"}],"termid":"SO:0001152"}


id: MOD:00274
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces the hydrogen atom of a cysteine sulfanyl group with a sulfanyl group, forming a disulfanyl group, and converting an L-cysteine residue to L-cysteine persulfide.","definition_xrefs":["PubMed:4276457","Unimod:421","ChEBI:28839","PubMed:8161529","RESID:AA0269","PubMed:15096637"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"},{"relation_name":"is_a","term_name":"thiolated residue","termid":"MOD:01886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"L-cysteine persulfide","synonyms":[{"name":"(R)-2-amino-3-disulfanylpropanoic acid","type":"exact"},{"name":"2-amino-3-disulfanylpropanoic acid","type":"exact"},{"name":"2-amino-3-hydrodisulfidopropanoic acid","type":"exact"},{"name":"2-amino-3-hydropersulfidopropanoic acid","type":"exact"},{"name":"2-amino-3-persulfhydrylpropanoic acid","type":"exact"},{"name":"3-(thiosulfeno)-alanine","type":"exact"},{"name":"3-disulfanylalanine","type":"exact"},{"name":"ACT_SITE Cysteine persulfide intermediate","type":"exact"},{"name":"L-cysteine persulfide","type":"exact"},{"name":"MOD_RES Cysteine persulfide","type":"exact"},{"name":"S-mercaptocysteine","type":"exact"},{"name":"S-sulfanylcysteine","type":"exact"},{"name":"Sulfide","type":"related"},{"name":"persulfide","type":"related"},{"name":"thiocysteine","type":"exact"}],"termid":"MOD:00274"}


id: GO:0048723
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head.","definition_xrefs":["GOC:rc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"clypeo-labral disc development","termid":"GO:0035213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"clypeus development","termid":"GO:0048723"}


id: PBO:0057653
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1245b","termid":"PBO:0057653"}


id: MONDO:1010585
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial goiter that occurs in American black bear.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial goiter, non-human animal","termid":"MONDO:1010053"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"familial goiter, American black bear","secondary_identifiers":["OMIA:000424-9643"],"termid":"MONDO:1010585","xrefs":{"Monarch":{"xref_id":"1010585"}}}


id: MOD:01391
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively crosslinks an L-cysteine residue and an L-valine residue, and C-5 methoxymethylates to form L-valine 5-(methoxymethyl)thiazole-4-carboxylic acid.","definition_xrefs":["RESID:AA0468","PubMed:7844053","PubMed:10625477","PubMed:1880060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thiazole/thiazoline ring crosslinked residues","termid":"MOD:01420"},{"relation_name":"is_a","term_name":"didehydrogenated residue","termid":"MOD:01888"},{"relation_name":"is_a","term_name":"crosslinked L-valine residue","termid":"MOD:02059"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"L-valine 5-(methoxymethyl)thiazole-4-carboxylic acid","synonyms":[{"name":"2-[(1S)-1-amino-2-methylpropyl]-5-(methoxymethyl)-1,3-thiazole-4-carboxylic acid","type":"exact"},{"name":"2-[1-azanyl-2-methylpropyl]-5-(methoxymethyl)-1,3-thiazole-4-carboxylic acid","type":"exact"},{"name":"CROSSLNK 5-(methoxymethyl)thiazole-4-carboxylic acid (Val-Cys)","type":"exact"},{"name":"L-valine 5-(methoxymethyl)thiazole-4-carboxylic acid","type":"exact"}],"termid":"MOD:01391"}


id: PBO:0000836
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulfite reductase Sir1","termid":"PBO:0000836"}


id: GO:1900034
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cellular response to heat.","definition_xrefs":["GOC:yaf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular response to stress","termid":"GO:0080135"},{"relation_name":"regulates","term_name":"cellular response to heat","termid":"GO:0034605"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cellular response to heat","secondary_identifiers":["Reactome:R-HSA-3371453","Reactome:R-HSA-3371571"],"synonyms":[{"name":"regulation of cellular response to heat stress","type":"exact"}],"termid":"GO:1900034"}


id: GO:0141162
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cAMP/PKA signal transduction.","definition_xrefs":["PMID:17376027"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cAMP/PKA signal transduction","termid":"GO:0141161"},{"relation_name":"is_a","term_name":"negative regulation of intracellular signal transduction","termid":"GO:1902532"},{"relation_name":"negatively_regulates","term_name":"cAMP/PKA signal transduction","termid":"GO:0141156"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of cAMP/PKA signal transduction","synonyms":[{"name":"negative regulation of cAMP/PKA signaling","type":"exact"}],"termid":"GO:0141162"}


id: PBO:0064130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cAMP-dependent protein kinase inhibitor beta","termid":"PBO:0064130"}


id: GO:0071009
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.","definition_xrefs":["GOC:pr","GOC:mah","ISBN:0879695897","PMID:16201866","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spliceosomal tri-snRNP complex","termid":"GO:0097526"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"U4atac/U6atac x U5 tri-snRNP complex","synonyms":[{"name":"U4atac/U6atac.U5 snRNP complex","type":"exact"}],"termid":"GO:0071009"}


id: PBO:0054461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1858","termid":"PBO:0054461"}


id: PBO:0066623
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RIC3 divergent transcript","termid":"PBO:0066623"}


id: GO:1901027
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of dextrin.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucan catabolic process","termid":"GO:0009251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"dextrin catabolic process","synonyms":[{"name":"dextrin breakdown","type":"exact"},{"name":"dextrin catabolism","type":"exact"},{"name":"dextrin degradation","type":"exact"}],"termid":"GO:1901027"}


id: PBO:0108509
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial Mpv17/PMP22 family protein Sym1, implicated in pyrimidine or lysine metabolism","termid":"PBO:0108509"}


id: PBO:0056902
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"macrophage migration inhibitory factor","termid":"PBO:0056902"}


id: PBO:0039038
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AGBL carboxypeptidase 1","termid":"PBO:0039038"}


id: GO:0030592
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.","definition_xrefs":["PMID:11592983","PMID:27471034","PMID:29361132","PMID:29520010"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA modification","termid":"GO:0006304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0008150"],"is_obsolete":false,"name":"DNA ADP-ribosylation","termid":"GO:0030592"}


id: MONDO:0021117
data:
  {"annotated_genes":["SJAG_04114","SJAG_03689","SJAG_00229","SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86334,86333,86865],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008903"},{"annotations":[85879],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011014"}]},"cv_name":"mondo","definition":"A benign or malignant, primary or metastatic neoplasm involving the lungs. Representative examples of benign neoplasms include adenoma, papilloma, chondroma, and endobronchial lipoma. Representative examples of malignant neoplasms include carcinoma, carcinoid tumor, sarcoma, and lymphoma.","definition_xrefs":["NCIT:C3200"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lung disorder","termid":"MONDO:0005275"},{"relation_name":"is_a","term_name":"respiratory tract neoplasm","termid":"MONDO:0020641"},{"relation_name":"is_a","term_name":"neoplasm of thorax","termid":"MONDO:0021350"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00229":null,"SJAG_03453":null,"SJAG_03689":null,"SJAG_04114":null},"genotype_count":0,"is_obsolete":false,"name":"lung neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ONCOTREE:LUNG","MEDGEN:7400","MESH:D008175","UMLS:C0024121"],"synonyms":[{"name":"lung","type":"related"},{"name":"lung neoplasm","type":"exact"},{"name":"lung neoplasm (disease)","type":"exact"},{"name":"lung neoplasms","type":"exact"},{"name":"lung tumor","type":"exact"},{"name":"lung tumour","type":"exact"},{"name":"neoplasm of lung","type":"exact"},{"name":"neoplasm of the lung","type":"exact"},{"name":"neoplasm, lung","type":"related"},{"name":"neoplasm, pulmonary","type":"related"},{"name":"neoplasms, lung","type":"related"},{"name":"neoplasms, pulmonary","type":"related"},{"name":"tumor of lung","type":"exact"},{"name":"tumor of the lung","type":"exact"},{"name":"tumour of lung","type":"exact"},{"name":"tumour of the lung","type":"exact"}],"termid":"MONDO:0021117","terms_by_termid":{"MONDO:0008903":null,"MONDO:0011014":null},"xrefs":{"Monarch":{"xref_id":"0021117"}}}


id: PBO:0079261
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TTC32 divergent transcript","termid":"PBO:0079261"}


id: GO:0090394
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biological process","termid":"GO:0048519"},{"relation_name":"is_a","term_name":"modulation of excitatory postsynaptic potential","termid":"GO:0098815"},{"relation_name":"negatively_regulates","term_name":"excitatory postsynaptic potential","termid":"GO:0060079"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of excitatory postsynaptic potential","synonyms":[{"name":"negative regulation of EPSP","type":"related"},{"name":"negative regulation of excitatory post-synaptic membrane potential","type":"exact"},{"name":"reduction of excitatory postsynaptic membrane potential","type":"exact"}],"termid":"GO:0090394"}


id: PBO:0091597
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"was previously incorrectly annotated as pex22","termid":"PBO:0091597"}


id: MONDO:0012078
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Joubert syndrome in which the cause of the disease is a mutation in the AHI1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Joubert syndrome with ocular defect","termid":"MONDO:0016364"},{"relation_name":"is_a","term_name":"Joubert syndrome","termid":"MONDO:0018772"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0020022","MONDO:0006025"],"is_obsolete":false,"name":"Joubert syndrome 3","secondary_identifiers":["NCIT:C148259","DOID:0110998","GARD:15435","MESH:C536295","UMLS:C1837713","OMIM:608629","MEDGEN:332931"],"synonyms":[{"name":"AHI1 Joubert syndrome","type":"exact"},{"name":"JBTS3","type":"exact"},{"name":"Joubert syndrome 3","type":"exact"},{"name":"Joubert syndrome caused by mutation in AHI1","type":"exact"},{"name":"Joubert syndrome type 3","type":"exact"}],"termid":"MONDO:0012078","xrefs":{"Monarch":{"xref_id":"0012078"}}}


id: PBO:0064182
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospholipase A2 group XI, pseudogene","termid":"PBO:0064182"}


id: PBO:0067998
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 300","termid":"PBO:0067998"}


id: GO:0102066
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete alpha-patchoulene synthase activityy (obsolete GO:0102066)","termid":"GO:0102066"}


id: MONDO:0005624
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Atrophic thyroiditis is an organ-specific autoimmune disease characterized by thyroid autoantibodies, functional hypothyroidism, and absence of goiter.","definition_xrefs":["doi:10.1007/978-1-60327-285-8_42"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune thyroid disease","termid":"MONDO:0005623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"atrophic thyroiditis","secondary_identifiers":["EFO:0006813","NANDO:2200336","MEDGEN:536775","SCTID:83664006","UMLS:C0238183"],"termid":"MONDO:0005624","xrefs":{"Monarch":{"xref_id":"0005624"}}}


id: FYPO:0006916
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which a cell executes a cell cycle phase transition normally (i.e. indistinguishably from wild type).","definition_xrefs":["PomBase:mah","GO:0044770"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cell cycle process","termid":"FYPO:0006915"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal cell cycle phase transition","termid":"FYPO:0006916"}


id: SO:0001567
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant where at least one base in the terminator codon is changed, but the terminator remains.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"terminator_codon_variant","termid":"SO:0001590"},{"relation_name":"is_a","term_name":"synonymous_variant","termid":"SO:0001819"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stop_retained_variant","secondary_identifiers":["http://snpeff.sourceforge.net/SnpEff_manual.html","http:www.ensembl.org/info/genome/variation/predicted_data.html#consequences"],"synonyms":[{"name":"Jannovar:stop_retained_variant","type":"exact"},{"name":"VAAST:stop_retained","type":"exact"},{"name":"VAAST:stop_retained_variant","type":"exact"},{"name":"VEP:stop_retained_variant","type":"exact"},{"name":"snpEff:NON_SYNONYMOUS_STOP","type":"exact"},{"name":"snpEff:SYNONYMOUS_STOP","type":"exact"},{"name":"stop retained variant","type":"exact"}],"termid":"SO:0001567"}


id: FYPO:0005420
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron assimilation RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Iron assimilation RNAs are transcribed from genes whose products are involved in any process in which iron is solubilized and transported into a cell.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased RNA level during vegetative growth","termid":"FYPO:0000825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0006551","FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"increased level of iron assimilation gene mRNA during vegetative growth","synonyms":[{"name":"increased iron assimilation gene mRNA accumulation during vegetative growth","type":"related"},{"name":"increased level of iron assimilation gene RNA during vegetative growth","type":"exact"},{"name":"increased level of iron assimilation gene mRNA during mitotic cell cycle","type":"related"},{"name":"increased level of iron assimilation gene transcripts during vegetative growth","type":"exact"}],"termid":"FYPO:0005420"}


id: GO:0031885
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 1 member 2 taste receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"taste receptor binding","termid":"GO:0031883"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"type 1 member 2 taste receptor binding","synonyms":[{"name":"type 1 member 2 taste receptor ligand","type":"narrow"}],"termid":"GO:0031885"}


id: PBO:0084626
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Methylene-fatty-acyl-phospholipid synthase; catalyzes the last two steps in phosphatidylcholine biosynthesis; also known as phospholipid methyltransferase","termid":"PBO:0084626"}


id: MONDO:0017624
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a form of familial primary hypomagnesemia (FPH), characterized by renal magnesium (Mg) and calcium (Ca) wasting, nephrocalcinosis, kidney failure and, in some cases, severe ocular impairment. Two subtypes of FHHNC are described: FHHNC with severe ocular involvement (FHHNCOI) and without severe ocular involvement (FHHN).","definition_xrefs":["Orphanet:306516"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial primary hypomagnesemia","termid":"MONDO:0018100"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005240","MONDO:0005066"],"is_obsolete":false,"name":"familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis","secondary_identifiers":["GARD:21254","UMLS:C5679977","MEDGEN:1843047"],"synonyms":[{"name":"FHHNC","type":"exact"},{"name":"Michellis-Castrillo syndrome","type":"exact"}],"termid":"MONDO:0017624","xrefs":{"Monarch":{"xref_id":"0017624"}}}


id: PBO:0087060
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L2A; homologous to mammalian ribosomal protein L2 and bacterial L2; RPL2A has a paralog, RPL2B, that arose from the whole genome duplication","termid":"PBO:0087060"}


id: PBO:0090808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thymidylate synthase / phosphopantothenoylcysteine decarboxylase / protein phosphatase inhibitor moonlighting protein Hal3/Tds1","termid":"PBO:0090808"}


id: GO:0031941
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A two-stranded helical polymer of the protein actin.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"actin filament","termid":"GO:0005884"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0015629"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0015629"],"is_obsolete":false,"name":"filamentous actin","secondary_identifiers":["Wikipedia:Actin"],"synonyms":[{"name":"F-actin","type":"exact"}],"termid":"GO:0031941"}


id: PBO:0040969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCL2 interacting protein 3 pseudogene 40","termid":"PBO:0040969"}


id: PR:O13786
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pep7 gene.","definition_xrefs":["UniProtKB:O13786","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar segregation protein pep7 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17G6.08","synonyms":[{"name":"Spom972h-pep7","type":"exact"}],"termid":"PR:O13786"}


id: PBO:0078622
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 71","termid":"PBO:0078622"}


id: PBO:0005820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uracil DNA N-glycosylase Thp1","termid":"PBO:0005820"}


id: PBO:0053039
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"La ribonucleoprotein 1B","termid":"PBO:0053039"}


id: FYPO:0000351
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the fungal-type cell wall is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell wall during vegetative growth","termid":"FYPO:0000027"},{"relation_name":"is_a","term_name":"abnormal cell wall morphology","termid":"FYPO:0002947"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002946"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0002946"],"is_obsolete":false,"name":"abnormal cell wall morphology during vegetative growth","synonyms":[{"name":"abnormal cell wall morphology during mitotic cell cycle","type":"related"},{"name":"cell wall morphology: abnormal during vegetative growth","type":"related"}],"termid":"FYPO:0000351"}


id: MOD:00529
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod N-linked glycosylation","definition_xrefs":["RESID:AA0151#var","Unimod:161"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N4-glycosyl-L-asparagine","termid":"MOD:00160"},{"relation_name":"is_a","term_name":"complex glycosylation","termid":"MOD:00725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"Hex3HexNAc2P1 N4-glycosylated asparagine","synonyms":[{"name":"Hex(3)HexNAc(2)P(1)","type":"related"},{"name":"Hex3HexNAc2P1","type":"related"}],"termid":"MOD:00529"}


id: PBO:0070368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY5 pseudogene 6","termid":"PBO:0070368"}


id: FYPO:0008012
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a vegetative cell dies at a level of mechanical stress that wild-type cells can normally withstand.","definition_xrefs":["PMID:34666001","PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vegetative cell phenotype","termid":"FYPO:0003755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"cell sensitive to mechanical stress","termid":"FYPO:0008012"}


id: GO:0047351
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 GTP + H+ = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H+.","definition_xrefs":["RHEA:18153"],"direct_ancestors":[{"relation_name":"is_a","term_name":"guanylyltransferase activity","termid":"GO:0070568"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016779"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0016779","GO:0003824"],"is_obsolete":false,"name":"GTP guanylyltransferase activity","secondary_identifiers":["MetaCyc:2.7.7.45-RXN","EC:2.7.7.45","KEGG_REACTION:R00012"],"synonyms":[{"name":"GTP:GTP guanylyltransferase activity","type":"broad"},{"name":"guanosine-triphosphate guanylyltransferase activity","type":"exact"}],"termid":"GO:0047351"}


id: GO:1905902
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of mesoderm formation.","definition_xrefs":["PMID:23939491","GOC:BHF","GOC:BHF_miRNA","GOC:rph","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of developmental process","termid":"GO:0050793"},{"relation_name":"regulates","term_name":"mesoderm formation","termid":"GO:0001707"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of mesoderm formation","termid":"GO:1905902"}


id: MOD:01100
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DeltaMass","termid":"MOD:00947"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HMP (hydroxymethylphenyl)/TFA adduct","termid":"MOD:01100"}


id: GO:1904874
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","GOC:BHF","GOC:BHF_telomere","PMID:25467444","GOC:nc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of biological process","termid":"GO:0048518"},{"relation_name":"is_a","term_name":"regulation of telomerase RNA localization to Cajal body","termid":"GO:1904872"},{"relation_name":"positively_regulates","term_name":"telomerase RNA localization to Cajal body","termid":"GO:0090671"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of telomerase RNA localization to Cajal body","synonyms":[{"name":"activation of telomerase RNA localization to Cajal body","type":"narrow"},{"name":"up regulation of telomerase RNA localization to Cajal body","type":"exact"},{"name":"up-regulation of telomerase RNA localization to Cajal body","type":"exact"},{"name":"upregulation of telomerase RNA localization to Cajal body","type":"exact"}],"termid":"GO:1904874"}


id: MONDO:0011903
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant Charcot-Marie-Tooth disease type 2J (CMT2J) is a form of axonal Charcot-Marie-Tooth disease, a peripheral sensorimotor neuropathy, characterized by a relatively late onset, pupillary abnormalities and deafness, in most patients, associated with distal weakness and muscle atrophy.","definition_xrefs":["Orphanet:99943"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease dominant intermediate D","termid":"MONDO:0011909"},{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease type 2","termid":"MONDO:0018993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244","MONDO:0000426"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease type 2J","secondary_identifiers":["icd11.foundation:1498789307","OMIM:607736","MESH:C535417","SCTID:717014003","MEDGEN:375107","UMLS:C1843153","GARD:9198","DOID:0110157"],"synonyms":[{"name":"CMT 2J","type":"related"},{"name":"CMT2J","type":"exact"},{"name":"Charcot Marie Tooth disease type 2J","type":"related"},{"name":"Charcot-Marie-Tooth disease type 2 with hearing loss and pupillary abnormalities","type":"exact"},{"name":"Charcot-Marie-Tooth disease, axonal, type 2J","type":"related"},{"name":"Charcot-Marie-Tooth disease, type 2, with hearing loss and pupillary abnormalities","type":"related"},{"name":"Charcot-Marie-Tooth disease, type 2J","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy type 2J","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy, type 2J","type":"related"},{"name":"autosomal dominant Charcot-Marie-Tooth disease type 2J","type":"related"}],"termid":"MONDO:0011903","xrefs":{"Monarch":{"xref_id":"0011903"}}}


id: GO:1900664
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of emodin biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ketone biosynthetic process","termid":"GO:0010566"},{"relation_name":"is_a","term_name":"regulation of secondary metabolite biosynthetic process","termid":"GO:1900376"},{"relation_name":"regulates","term_name":"emodin biosynthetic process","termid":"GO:1900575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"regulation of emodin biosynthetic process","synonyms":[{"name":"regulation of emodin anabolism","type":"exact"},{"name":"regulation of emodin biosynthesis","type":"exact"},{"name":"regulation of emodin formation","type":"exact"},{"name":"regulation of emodin synthesis","type":"exact"}],"termid":"GO:1900664"}


id: GO:0044587
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.","definition_xrefs":["GOC:mengo_curators","GOC:tt"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oligosaccharide binding","termid":"GO:0070492"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"cellopentaose binding","termid":"GO:0044587"}


id: PBO:0061649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nudix hydrolase 21","termid":"PBO:0061649"}


id: PBO:0039933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho guanine nucleotide exchange factor 38","termid":"PBO:0039933"}


id: PBO:0064108
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polycystin 1, transient receptor potential channel interacting","termid":"PBO:0064108"}


id: MONDO:0008962
data:
  {"annotated_genes":["SJAG_03011","SJAG_00938"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86554,86555],"is_not":false,"summary":null,"term":"MONDO:0008962"}]},"cv_name":"mondo","definition":"A Griscelli syndrome characterized by silvery gray sheen of the hair, hypopigmentation of the skin and neurological impairment without immunodeficiency that has material basis in mutations in the MYO5A gene on chromosome 15q21.2.","definition_xrefs":["DOID:0060832","PMID:9207796","PMID:12452176"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Griscelli syndrome","termid":"MONDO:0018306"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00938":null,"SJAG_03011":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066"],"is_obsolete":false,"name":"Griscelli syndrome type 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:214450","icd11.foundation:875700770","Orphanet:79476","GARD:2566","MESH:C537301","UMLS:C1859194","ICD10CM:E70.3","MEDGEN:347092"],"synonyms":[{"name":"GS1","type":"exact"},{"name":"Griscelli disease type 1","type":"related"},{"name":"Griscelli syndrome type 1","type":"exact"},{"name":"Griscelli syndrome with neurologic impairment","type":"related"},{"name":"Griscelli syndrome with neurological impairment","type":"exact"},{"name":"Griscelli syndrome, cutaneous and neurologic type","type":"related"},{"name":"Griscelli syndrome, cutaneous and neurological type","type":"exact"},{"name":"Griscelli syndrome, type 1","type":"related"},{"name":"Griscelli-PruniC)ras syndrome type 1","type":"exact"},{"name":"Griscelli-Pruniéras syndrome type 1","type":"exact"},{"name":"hypopigmentation-neurologic impairment syndrome","type":"exact"},{"name":"partial albinism and primary neurologic disease without hemophagocytic syndrome","type":"related"},{"name":"pigmentary dilution of the skin and hair, the presence of large clumps of pigment in hair shafts","type":"related"}],"termid":"MONDO:0008962","terms_by_termid":{"MONDO:0008962":null},"xrefs":{"Monarch":{"xref_id":"0008962"}}}


id: GO:0110021
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.","definition_xrefs":["PMID:26512644","GOC:rph","GOC:BHF_miRNA","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myoblast proliferation","termid":"GO:0051450"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac muscle myoblast proliferation","termid":"GO:0110021"}


id: MONDO:0008192
data:
  {"annotated_genes":["SJAG_02398"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85374],"is_not":false,"summary":null,"term":"MONDO:0008192"}]},"cv_name":"mondo","definition":"Any paraganglioma in which the cause of the disease is a mutation in the SDHD gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"paraganglioma","termid":"MONDO:0000448"},{"relation_name":"is_a","term_name":"hereditary pheochromocytoma-paraganglioma","termid":"MONDO:0017366"},{"relation_name":"is_a","term_name":"adrenal gland neoplasm","termid":"MONDO:0021227"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02398":null},"genotype_count":0,"is_obsolete":false,"name":"paragangliomas 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:488134","UMLS:C3494181","OMIM:168000","GARD:7324"],"synonyms":[{"name":"PGL1","type":"related"},{"name":"Paragangliomata","type":"related"},{"name":"SDHD paraganglioma","type":"exact"},{"name":"carotid body tumors","type":"related"},{"name":"carotid body tumours","type":"related"},{"name":"chemodectomas","type":"related"},{"name":"glomus jugulare tumors","type":"related"},{"name":"glomus jugulare tumours","type":"related"},{"name":"glomus tumors, familial, 1","type":"related"},{"name":"paraganglioma caused by mutation in SDHD","type":"exact"},{"name":"paraganglioma, carotid body","type":"related"},{"name":"paragangliomas 1","type":"exact"},{"name":"paragangliomas 1, with or without deafness","type":"exact"},{"name":"paragangliomas type 1","type":"exact"},{"name":"paragangliomas with sensorineural hearing loss","type":"related"},{"name":"paragangliomas, familial nonchromaffin, 1","type":"related"},{"name":"paragangliomas, familial, 1","type":"related"}],"termid":"MONDO:0008192","terms_by_termid":{"MONDO:0008192":null},"xrefs":{"Monarch":{"xref_id":"0008192"}}}


id: PBO:0046252
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongator acetyltransferase complex subunit 1","termid":"PBO:0046252"}


id: PBO:0073156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SEC61 translocon subunit alpha 2","termid":"PBO:0073156"}


id: MONDO:1012492
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"neurodegenerative vacuolar storage disease, non-human animal","termid":"MONDO:1011893"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurodegenerative vacuolar storage disease, dog","secondary_identifiers":["OMIA:001954-9615"],"termid":"MONDO:1012492","xrefs":{"Monarch":{"xref_id":"1012492"}}}


id: PBO:0089720
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA (m1A) methyltransferase non-catalytic subunit Gcd10","termid":"PBO:0089720"}


id: MOD:01155
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively results from forming an adduct with a compound containing a lipid-like group either through acylation, alkylation, or amidation.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by chemical process","termid":"MOD:01156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipoconjugated residue","termid":"MOD:01155"}


id: FYPO:0007676
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the directed movement of sterols within cells is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:32320462","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal transport","termid":"FYPO:0001071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000138","FYPO:0001312","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal intracellular sterol transport","termid":"FYPO:0007676"}


id: PR:Q9URY8
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A chloride anion exchanger that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02282","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulfate permease C869.05c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC869.05c","secondary_identifiers":["UniProtKB:Q9URY8"],"synonyms":[{"name":"Spom972h-SLC26A3","type":"exact"}],"termid":"PR:Q9URY8"}


id: GO:0140285
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.","definition_xrefs":["PMID:25416943","PMID:30220460"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle fission","termid":"GO:0048285"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endosome fission","termid":"GO:0140285"}


id: GO:0032688
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.","definition_xrefs":["PMID:15546383","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of type I interferon production","termid":"GO:0032480"},{"relation_name":"is_a","term_name":"regulation of interferon-beta production","termid":"GO:0032648"},{"relation_name":"negatively_regulates","term_name":"interferon-beta production","termid":"GO:0032608"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of interferon-beta production","secondary_identifiers":["GO:0045358","GO:0035548"],"synonyms":[{"name":"down regulation of interferon-beta production","type":"exact"},{"name":"down-regulation of interferon-beta production","type":"exact"},{"name":"downregulation of interferon-beta production","type":"exact"},{"name":"inhibition of interferon-beta production","type":"narrow"},{"name":"negative regulation of IFN-beta production","type":"exact"},{"name":"negative regulation of interferon-beta biosynthetic process","type":"narrow"},{"name":"negative regulation of interferon-beta secretion","type":"narrow"}],"termid":"GO:0032688"}


id: PBO:0029745
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_calcium_import","termid":"PBO:0029745"}


id: GO:0008110
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.","definition_xrefs":["EC:2.6.1.38","RHEA:16565"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transaminase activity","termid":"GO:0008483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016769"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016769","GO:0003674"],"is_obsolete":false,"name":"L-histidine:2-oxoglutarate aminotransferase activity","secondary_identifiers":["MetaCyc:HISTTRANSAM-RXN","KEGG_REACTION:R01161"],"synonyms":[{"name":"histidine aminotransferase activity","type":"broad"},{"name":"histidine transaminase activity","type":"broad"},{"name":"histidine-2-oxoglutarate aminotransferase activity","type":"related"}],"termid":"GO:0008110"}


id: PBO:0061798
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ornithine decarboxylase pseudogene","termid":"PBO:0061798"}


id: PBO:0045407
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DPPA3 pseudogene 9","termid":"PBO:0045407"}


id: PBO:0017548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar amino acid transmembrane transporter Atg22","termid":"PBO:0017548"}


id: PR:O42951
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- abz2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42951"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aminodeoxychorismate lyase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC19G7.02","synonyms":[{"name":"4-amino-4-deoxychorismate lyase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ADC lyase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ADCL (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-abz2","type":"exact"}],"termid":"PR:O42951"}


id: FYPO:0005094
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the S-phase DNA damage checkpoint is lower than in wild type during a cellular response to hydroxyurea.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic cell cycle regulation during cellular response to hydroxyurea","termid":"FYPO:0001933"},{"relation_name":"is_a","term_name":"decreased duration of S-phase DNA damage checkpoint","termid":"FYPO:0004371"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000631","FYPO:0000298","FYPO:0001985","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea","synonyms":[{"name":"decreased duration of S-phase DNA damage checkpoint activation during cellular response to hydroxyurea","type":"exact"},{"name":"decreased duration of S-phase DNA damage checkpoint during cellular response to HU","type":"exact"},{"name":"decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea during mitotic cell cycle","type":"exact"},{"name":"decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea during vegetative growth","type":"exact"},{"name":"decreased duration of intra-S DNA damage checkpoint during cellular response to hydroxyurea","type":"exact"},{"name":"decreased duration of mitotic S-phase DNA damage checkpoint during cellular response to hydroxyurea","type":"exact"},{"name":"premature S-phase DNA damage checkpoint deactivation during cellular response to hydroxyurea","type":"related"},{"name":"reduced duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea","type":"exact"}],"termid":"FYPO:0005094"}


id: GO:0009119
data:
  {"annotated_genes":["SJAG_01859","SJAG_02582","SJAG_02580","SJAG_01070","SJAG_03771","SJAG_03881","SJAG_06634","SJAG_00134","SJAG_00694","SJAG_02959","SJAG_03096","SJAG_01673","SJAG_00044"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88395],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046086"},{"annotations":[87103,87102],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006154"},{"annotations":[113144,113145,90059],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046085"},{"annotations":[116282],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006169"},{"annotations":[107838,88707],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009972"},{"annotations":[107962],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006190"},{"annotations":[89288,93040,93258,115283],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006166"},{"annotations":[111363],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046132"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside metabolic process","termid":"GO:0009116"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00044":null,"SJAG_00134":null,"SJAG_00694":null,"SJAG_01070":null,"SJAG_01673":null,"SJAG_01859":null,"SJAG_02580":null,"SJAG_02582":null,"SJAG_02959":null,"SJAG_03096":null,"SJAG_03771":null,"SJAG_03881":null,"SJAG_06634":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0055086"],"is_obsolete":false,"name":"ribonucleoside metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"ribonucleoside metabolism","type":"exact"}],"termid":"GO:0009119","terms_by_termid":{"GO:0006154":null,"GO:0006166":null,"GO:0006169":null,"GO:0006190":null,"GO:0009972":null,"GO:0046085":null,"GO:0046086":null,"GO:0046132":null}}


id: PBO:0051502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interactor of HORMAD1 1","termid":"PBO:0051502"}


id: PBO:0040320
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase F1 subunit delta","termid":"PBO:0040320"}


id: GO:0005973
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete fibrinogen beta chain (obsolete GO:0005973)","synonyms":[{"name":"fibrinogen beta chain","type":"exact"}],"termid":"GO:0005973"}


id: GO:1990248
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.","definition_xrefs":["PMID:15660129"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transcription from RNA polymerase II promoter in response to DNA damage (obsolete GO:1990248)","termid":"GO:1990248"}


id: PBO:0064389
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PMS1 homolog 2, mismatch repair system component pseudogene 11","termid":"PBO:0064389"}


id: MONDO:0009486
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive form of Kenny-Caffey syndrome due to mutation(s) in the TBCE gene, encoding tubulin-specific chaperone E. This condition is characterized by hypoparathyroidism with hypocalcemia, marked growth retardation, craniofacial anomalies, absent diploic space in the skull, cortical thickening of long bones with medullary stenosis, and small hands and feet.","definition_xrefs":["NCIT:C130992"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"Kenny-Caffey syndrome","termid":"MONDO:0016516"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive Kenny-Caffey syndrome","secondary_identifiers":["MEDGEN:340923","MESH:C537021","OMIM:244460","Orphanet:93324","UMLS:C1855648","DOID:0080722","GARD:8367"],"synonyms":[{"name":"KCS1","type":"related"},{"name":"Kcs","type":"related"},{"name":"Kenny-Caffey syndrome type 1","type":"exact"},{"name":"Kenny-Caffey syndrome, autosomal recessive","type":"exact"},{"name":"Kenny-Caffey syndrome, type 1","type":"related"}],"termid":"MONDO:0009486","xrefs":{"Monarch":{"xref_id":"0009486"}}}


id: PBO:0062267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily G member 3 (gene/pseudogene)","termid":"PBO:0062267"}


id: GO:1905318
data:
  {"annotated_genes":["SJAG_04259","SJAG_01330","SJAG_01082","SJAG_03327"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[105785,113941],"is_not":false,"summary":null,"term":"GO:1905318"},{"annotations":[113226],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1905326"},{"annotations":[100826],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:1905325"}]},"cv_name":"biological_process","definition":"Any spindle assembly checkpoint that is involved in meiosis I.","definition_xrefs":["PMID:26483559","GO_REF:0000060","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic spindle assembly checkpoint signaling","termid":"GO:0033316"},{"relation_name":"is_a","term_name":"negative regulation of meiosis I","termid":"GO:0110029"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01082":null,"SJAG_01330":null,"SJAG_03327":null,"SJAG_04259":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0140013"},{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0140013"},{"rel_name":"negatively_regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0023052","GO:0008150","GO:0140013","GO:0007049"],"is_obsolete":false,"name":"meiosis I spindle assembly checkpoint signaling","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"meiosis I spindle assembly checkpoint","type":"exact"}],"termid":"GO:1905318","terms_by_termid":{"GO:1905318":null,"GO:1905325":null,"GO:1905326":null}}


id: MONDO:0971138
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"disorder of lysosomal-related organelles","termid":"MONDO:0017739"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"progressive hypotonia-intellectual disability-facial dysmorphism syndrome due to FYVE-defective RBSN","secondary_identifiers":["Orphanet:675782"],"termid":"MONDO:0971138","xrefs":{"Monarch":{"xref_id":"0971138"}}}


id: PR:O13904
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug84 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13904"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 84 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22A12.13","synonyms":[{"name":"Spom972h-mug84","type":"exact"}],"termid":"PR:O13904"}


id: PBO:0064936
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase domain and WD repeat containing 1","termid":"PBO:0064936"}


id: PBO:0051373
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin kappa variable 3D-34 (pseudogene)","termid":"PBO:0051373"}


id: MONDO:1011115
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cryptorchidism that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cryptorchidism, non-human animal","termid":"MONDO:1010275"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cryptorchidism, cattle","secondary_identifiers":["OMIA:000243-9913"],"termid":"MONDO:1011115","xrefs":{"Monarch":{"xref_id":"1011115"}}}


id: GO:0015361
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.","definition_xrefs":["TC:2.A.47.1.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium:dicarboxylate symporter activity","termid":"GO:0017153"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"low-affinity sodium:dicarboxylate symporter activity","secondary_identifiers":["Reactome:R-HSA-433131"],"synonyms":[{"name":"low affinity sodium:dicarboxylate cotransporter activity","type":"broad"},{"name":"low affinity sodium:dicarboxylate symporter activity","type":"exact"}],"termid":"GO:0015361"}


id: MONDO:0100357
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mild or intermediate form of a genetic disease.","direct_ancestors":[{"relation_name":"is_a","term_name":"classic or non-classic genetic disease presentation","termid":"MONDO:0100355"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-classic presentation","termid":"MONDO:0100357","xrefs":{"Monarch":{"xref_id":"0100357"}}}


id: MONDO:0006800
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of apraxia characterized by an acquired inability to carry out a complex motor activity despite the ability to mentally formulate the action. This condition has been attributed to a disruption of connections between the dominant parietal cortex and supplementary and premotor cortical regions in both hemispheres. (From Adams et al., Principles of Neurology, 6th ed, p57)","definition_xrefs":["MESH:D020240"],"direct_ancestors":[{"relation_name":"is_a","term_name":"apraxia","termid":"MONDO:0000665"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ideomotor apraxia","secondary_identifiers":["MEDGEN:115961","SCTID:229706001","DOID:4627","UMLS:C0234523","EFO:1000980","ICD9:315.8","MedDRA:10021216"],"synonyms":[{"name":"classic apraxia","type":"exact"},{"name":"classic apraxia (finding) [ambiguous]","type":"exact"},{"name":"ideomotor dyspraxia","type":"exact"},{"name":"limb-kinetic apraxia","type":"exact"},{"name":"limb-kinetic apraxia (finding)","type":"exact"},{"name":"transcortical apraxia","type":"exact"},{"name":"transcortical apraxia (finding)","type":"exact"}],"termid":"MONDO:0006800","xrefs":{"Monarch":{"xref_id":"0006800"}}}


id: PBO:0026852
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_to_chromatin_at_long_terminal_repeat","termid":"PBO:0026852"}


id: PBO:0005583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA (uracil) methyltransferase (predicted)","termid":"PBO:0005583"}


id: MONDO:0700205
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ehrlichiosis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Anaplasmataceae infectious disease, non-human animal","termid":"MONDO:0700113"},{"relation_name":"is_a","term_name":"tick-borne infectious disease, non-human animal","termid":"MONDO:0700201"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ehrlichiosis, non-human animal","termid":"MONDO:0700205","xrefs":{"Monarch":{"xref_id":"0700205"}}}


id: GO:1905898
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.","definition_xrefs":["GOC:aruk","GO_REF:0000058","PMID:21803450","GOC:TermGenie","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cellular process","termid":"GO:0048522"},{"relation_name":"is_a","term_name":"positive regulation of response to stimulus","termid":"GO:0048584"},{"relation_name":"is_a","term_name":"regulation of response to endoplasmic reticulum stress","termid":"GO:1905897"},{"relation_name":"positively_regulates","term_name":"response to endoplasmic reticulum stress","termid":"GO:0034976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of response to endoplasmic reticulum stress","synonyms":[{"name":"activation of ER stress response","type":"narrow"},{"name":"activation of cellular response to endoplasmic reticulum stress","type":"narrow"},{"name":"activation of response to ER stress","type":"narrow"},{"name":"activation of response to endoplasmic reticulum stress","type":"narrow"},{"name":"positive regulation of ER stress response","type":"exact"},{"name":"positive regulation of cellular response to endoplasmic reticulum stress","type":"exact"},{"name":"positive regulation of response to ER stress","type":"exact"},{"name":"up regulation of ER stress response","type":"exact"},{"name":"up regulation of cellular response to endoplasmic reticulum stress","type":"exact"},{"name":"up regulation of response to ER stress","type":"exact"},{"name":"up regulation of response to endoplasmic reticulum stress","type":"exact"},{"name":"up-regulation of ER stress response","type":"exact"},{"name":"up-regulation of cellular response to endoplasmic reticulum stress","type":"exact"},{"name":"up-regulation of response to ER stress","type":"exact"},{"name":"up-regulation of response to endoplasmic reticulum stress","type":"exact"},{"name":"upregulation of ER stress response","type":"exact"},{"name":"upregulation of cellular response to endoplasmic reticulum stress","type":"exact"},{"name":"upregulation of response to ER stress","type":"exact"},{"name":"upregulation of response to endoplasmic reticulum stress","type":"exact"}],"termid":"GO:1905898"}


id: MOD:00405
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that is produced by formation of an adduct of a cysteine residue with the Applied Biosystems original isotope-coded affinity tag d8 reagent.","definition_xrefs":["Unimod:12#C"],"direct_ancestors":[{"relation_name":"is_a","term_name":"(2)H deuterium tagged reagent","termid":"MOD:01431"},{"relation_name":"is_a","term_name":"isotope tagged sufhydryl reagent modified cysteine","termid":"MOD:01820"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"Applied Biosystems original ICAT(TM) d8 modified cysteine","synonyms":[{"name":"Applied Biosystems original ICAT(TM) d8","type":"related"},{"name":"ICAT-D:2H(8)","type":"related"}],"termid":"MOD:00405"}


id: PR:O74411
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- meu10 gene.","definition_xrefs":["UniProtKB:O74411","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic expression up-regulated protein 10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1223.12c","synonyms":[{"name":"Spom972h-meu10","type":"exact"}],"termid":"PR:O74411"}


id: GO:0097609
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus.","definition_xrefs":["Wikipedia:Dinoflagellate#Morphology","GOC:at"],"direct_ancestors":[{"relation_name":"is_a","term_name":"9+2 motile cilium","termid":"GO:0097729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"longitudinal flagellum","synonyms":[{"name":"longitudinal cilium","type":"exact"}],"termid":"GO:0097609"}


id: PBO:0003451
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA polymerase delta subunit Cdc27","termid":"PBO:0003451"}


id: PBO:0059573
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metallothionein 1X pseudogene 1","termid":"PBO:0059573"}


id: PBO:0005581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"short chain dehydrogenase pseudogene","termid":"PBO:0005581"}


id: MONDO:0012364
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A dilated cardiomyopathy that has material basis in variation in the chromosome region 7q22.3-q31.1.","definition_xrefs":["DOID:0110442","PMID:16228230"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"dilated cardiomyopathy 1Q","secondary_identifiers":["MESH:C563688","UMLS:C1835926","MEDGEN:332088","OMIM:609915","GARD:15470"],"synonyms":[{"name":"CMD1Q","type":"exact"},{"name":"cardiomyopathy, dilated, 1Q","type":"related"},{"name":"dilated cardiomyopathy type 1Q","type":"exact"}],"termid":"MONDO:0012364","xrefs":{"Monarch":{"xref_id":"0012364"}}}


id: GO:0033652
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell plastid","termid":"GO:0033651"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host cell chloroplast","termid":"GO:0033652"}


id: GO:0047779
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H+ + phosphate.","definition_xrefs":["RHEA:21472","EC:6.2.1.18"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acid-thiol ligase activity","termid":"GO:0016878"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016874"],"is_obsolete":false,"name":"citrate-CoA ligase activity","secondary_identifiers":["KEGG_REACTION:R01322","MetaCyc:CITRATE--COA-LIGASE-RXN"],"synonyms":[{"name":"citrate thiokinase activity","type":"related"},{"name":"citrate:CoA ligase (ADP-forming)","type":"related"},{"name":"citrate:CoA ligase activity","type":"related"},{"name":"citryl-CoA synthetase activity","type":"related"}],"termid":"GO:0047779"}


id: MONDO:0017520
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"symbrachydactyly of hands and feet","termid":"MONDO:0015516"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"symbrachydactyly of hand and foot, bilateral","secondary_identifiers":["Orphanet:295138","UMLS:C2919807","MEDGEN:754111"],"termid":"MONDO:0017520","xrefs":{"Monarch":{"xref_id":"0017520"}}}


id: PBO:0053876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1152","termid":"PBO:0053876"}


id: PBO:0049300
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutathione S-transferase mu 3","termid":"PBO:0049300"}


id: GO:0051365
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.","definition_xrefs":["GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to starvation","termid":"GO:0009267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to potassium ion starvation","synonyms":[{"name":"cellular response to K+ ion deprivation","type":"exact"},{"name":"cellular response to K+ ion starvation","type":"exact"},{"name":"cellular response to potassium ion deprivation","type":"exact"},{"name":"cellular response to potassium starvation","type":"exact"}],"termid":"GO:0051365"}


id: GO:0006673
data:
  {"annotated_genes":["SJAG_03953","SJAG_04878","SJAG_00506","SJAG_03015","SJAG_02168","SJAG_04913","SJAG_05311"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94643],"is_not":false,"summary":null,"term":"GO:0006673"},{"annotations":[97004],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006676"},{"annotations":[90251,91314,95234,111981,94754],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051999"},{"annotations":[91315,111982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006675"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.","definition_xrefs":["PMID:19726565"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid metabolic process","termid":"GO:0006644"},{"relation_name":"is_a","term_name":"sphingolipid metabolic process","termid":"GO:0006665"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00506":null,"SJAG_02168":null,"SJAG_03015":null,"SJAG_03953":null,"SJAG_04878":null,"SJAG_04913":null,"SJAG_05311":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"inositol phosphoceramide metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0006674"],"synonyms":[{"name":"inositol phosphorylceramide metabolic process","type":"exact"},{"name":"inositol phosphorylceramide metabolism","type":"exact"},{"name":"inositolphosphoceramide metabolism","type":"exact"}],"termid":"GO:0006673","terms_by_termid":{"GO:0006673":null,"GO:0006675":null,"GO:0006676":null,"GO:0051999":null}}


id: PBO:0000557
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin cortical patch component Lsb4 (predicted)","termid":"PBO:0000557"}


id: PBO:0035725
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H3-K14_acetylation_during_vegetative_growth","termid":"PBO:0035725"}


id: PBO:0081388
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 227","termid":"PBO:0081388"}


id: PBO:0055109
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2527","termid":"PBO:0055109"}


id: FYPO:0002723
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased during a cellular response to cadmium ion.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cellular pigment accumulation","termid":"FYPO:0000741"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular pigment accumulation during cellular response to cadmium ion","synonyms":[{"name":"abnormal cellular pigment accumulation during cellular response to cadmium ion","type":"exact"},{"name":"altered colony color during cellular response to cadmium ion","type":"related"},{"name":"altered colony colour during cellular response to cadmium ion","type":"related"},{"name":"increased cellular pigment accumulation during cellular response to cadmium","type":"exact"},{"name":"increased cellular pigment accumulation during cellular response to cadmium ion during mitotic cell cycle","type":"related"},{"name":"increased cellular pigment accumulation during cellular response to cadmium ion during vegetative growth","type":"exact"}],"termid":"FYPO:0002723"}


id: PBO:0075505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spermatogenesis associated serine rich 2 like","termid":"PBO:0075505"}


id: PBO:0063387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"programmed cell death 5 pseudogene 1","termid":"PBO:0063387"}


id: _global:qualifier
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A relation that holds between an attribute or a qualifier and another attribute.","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"qualifier","secondary_identifiers":["RO:0002573"],"termid":"_global:qualifier"}


id: PR:O74526
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A myosin light chain kinase 3 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine-protein kinase C70.05c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC70.05c","secondary_identifiers":["UniProtKB:O74526"],"synonyms":[{"name":"Spom972h-MYLK3","type":"exact"}],"termid":"PR:O74526"}


id: PR:Q8NIL3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An uncharacterized isomerase YddE that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO02323"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"antisense-enhancing sequence 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBPB21E7.07","secondary_identifiers":["UniProtKB:Q8NIL3"],"synonyms":[{"name":"AES factor 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-yddE","type":"exact"}],"termid":"PR:Q8NIL3"}


id: PBO:0002482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome component beta 2 (predicted)","termid":"PBO:0002482"}


id: GO:0015450
data:
  {"annotated_genes":["SJAG_03560","SJAG_03415","SJAG_03502","SJAG_03358","SJAG_01597","SJAG_01879","SJAG_03515","SJAG_00373","SJAG_02077"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[90409,96388,99044,99813,102769,104659,107036,107057,111251],"is_not":false,"summary":null,"term":"GO:0015450"}]},"cv_name":"molecular_function","definition":"Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.","definition_xrefs":["GOC:mtg_transport","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein transmembrane transporter activity","termid":"GO:0008320"},{"relation_name":"is_a","term_name":"ATPase-coupled transmembrane transporter activity","termid":"GO:0042626"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00373":null,"SJAG_01597":null,"SJAG_01879":null,"SJAG_02077":null,"SJAG_03358":null,"SJAG_03415":null,"SJAG_03502":null,"SJAG_03515":null,"SJAG_03560":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140318"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0140318","GO:0022857"],"is_obsolete":false,"name":"protein-transporting ATPase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-1222523"],"synonyms":[{"name":"P-P-bond-hydrolysis-driven protein transmembrane transporter activity","type":"related"},{"name":"protein translocase activity","type":"exact"}],"termid":"GO:0015450","terms_by_termid":{"GO:0015450":null}}


id: PBO:0059443
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"membrane spanning 4-domains A14","termid":"PBO:0059443"}


id: GO:0047101
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: [a branched-chain alpha-keto acid] + CoA + NAD+ = [a branched-chain acyl-CoA] + CO2 + NADH. This enzyme system catalyzes the oxidative decarboxylation of branched-chain alpha-keto acids derived from L-leucine, L-isoleucine, and L-valine to branched-chain acyl-CoAs.","definition_xrefs":["EC:1.2.1.25"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","termid":"GO:0016620"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"branched-chain alpha-keto acid dehydrogenase activity","secondary_identifiers":["MetaCyc:1.2.1.25-RXN"],"synonyms":[{"name":"2-oxoisovalerate dehydrogenase (acylating) activity","type":"narrow"},{"name":"2-oxoisovalerate dehydrogenase activity","type":"related"},{"name":"3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)","type":"related"}],"termid":"GO:0047101"}


id: GO:2000998
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of catabolic process","termid":"GO:0009895"},{"relation_name":"is_a","term_name":"negative regulation of macromolecule metabolic process","termid":"GO:0010605"},{"relation_name":"is_a","term_name":"negative regulation of carbohydrate metabolic process","termid":"GO:0045912"},{"relation_name":"is_a","term_name":"regulation of cellulose catabolic process","termid":"GO:2000997"},{"relation_name":"negatively_regulates","term_name":"cellulose catabolic process","termid":"GO:0030245"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"negatively_regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"negative regulation of cellulose catabolic process","synonyms":[{"name":"negative regulation of cellulose breakdown","type":"exact"},{"name":"negative regulation of cellulose catabolism","type":"exact"},{"name":"negative regulation of cellulose degradation","type":"exact"}],"termid":"GO:2000998"}


id: PBO:0071682
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L37 pseudogene 14","termid":"PBO:0071682"}


id: PBO:0059761
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO3 pseudogene 35","termid":"PBO:0059761"}


id: FYPO:0004522
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated) and is curved along the long axis, and undergoes one or two rounds of cell division and then dies.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable after spore germination, single or double cell division, branched, elongated cell","termid":"FYPO:0004521"},{"relation_name":"is_a","term_name":"inviable after spore germination, single or double cell division, curved, elongated cell","termid":"FYPO:0004523"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000004","FYPO:0001320","FYPO:0000005"],"is_obsolete":false,"name":"inviable after spore germination, single or double cell division, branched, curved, elongated cell","synonyms":[{"name":"inviable after spore germination, single or double cell division, elongated, curved and branched cell","type":"exact"},{"name":"inviable following spore germination, single or double cell division, branched, curved, elongated cell","type":"exact"},{"name":"inviable germinated spore, single or double cell division, branched, curved, elongated cell","type":"exact"},{"name":"lethal after spore germination, single or double cell division, branched, curved, elongated cell","type":"exact"}],"termid":"FYPO:0004522"}


id: GO:0030084
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.","definition_xrefs":["PMID:8825475"],"direct_ancestors":[{"relation_name":"is_a","term_name":"PSI associated light-harvesting complex I","termid":"GO:0009518"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"PSI associated light-harvesting complex I, LHCIb subcomplex","termid":"GO:0030084"}


id: GO:1903899
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.","definition_xrefs":["GO_REF:0000058","GOC:PARL","GOC:bf","PMID:22013210","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of endoplasmic reticulum unfolded protein response","termid":"GO:1900103"},{"relation_name":"is_a","term_name":"regulation of PERK-mediated unfolded protein response","termid":"GO:1903897"},{"relation_name":"positively_regulates","term_name":"PERK-mediated unfolded protein response","termid":"GO:0036499"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of PERK-mediated unfolded protein response","synonyms":[{"name":"activation of PERK branch of UPR","type":"narrow"},{"name":"activation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"activation of PERK-mediated unfolded protein response","type":"narrow"},{"name":"activation of PKR-like ER kinase signal transduction","type":"narrow"},{"name":"activation of UPR signaling by PERK stress sensor","type":"narrow"},{"name":"activation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"narrow"},{"name":"positive regulation of EIF2AK3-mediated unfolded protein response","type":"related"},{"name":"positive regulation of PERK branch of UPR","type":"exact"},{"name":"positive regulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"positive regulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"positive regulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"positive regulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"},{"name":"up regulation of PERK branch of UPR","type":"exact"},{"name":"up regulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"up regulation of PERK-mediated unfolded protein response","type":"exact"},{"name":"up regulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"up regulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"up regulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"},{"name":"up-regulation of PERK branch of UPR","type":"exact"},{"name":"up-regulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"up-regulation of PERK-mediated unfolded protein response","type":"exact"},{"name":"up-regulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"up-regulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"up-regulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"},{"name":"upregulation of PERK branch of UPR","type":"exact"},{"name":"upregulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"upregulation of PERK-mediated unfolded protein response","type":"exact"},{"name":"upregulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"upregulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"upregulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"}],"termid":"GO:1903899"}


id: GO:0052458
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by organism of symbiont non-apoptotic programmed cell death (obsolete GO:0052458)","synonyms":[{"name":"modulation by organism of symbiont non-apoptotic programmed cell death","type":"exact"}],"termid":"GO:0052458"}


id: PBO:0064111
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PKD1L1 antisense RNA 1","termid":"PBO:0064111"}


id: PBO:0065108
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein kinase C beta","termid":"PBO:0065108"}


id: GO:0061325
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.","definition_xrefs":["GOC:mtg_heart","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell proliferation involved in heart morphogenesis","termid":"GO:0061323"},{"relation_name":"part_of","term_name":"outflow tract morphogenesis","termid":"GO:0003151"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell proliferation involved in outflow tract morphogenesis","termid":"GO:0061325"}


id: GO:0003727
data:
  {"annotated_genes":["SJAG_03876","SJAG_03916","SJAG_04210","SJAG_01201","SJAG_01643","SJAG_02621","SJAG_02808","SJAG_03283","SJAG_03460","SJAG_04574","SJAG_03214","SJAG_05010","SJAG_04601","SJAG_00145","SJAG_03745","SJAG_03747","SJAG_02469","SJAG_03448","SJAG_01910","SJAG_01327","SJAG_03433","SJAG_00425","SJAG_02043","SJAG_04427","SJAG_00884","SJAG_04880","SJAG_01436","SJAG_01650","SJAG_01222","SJAG_04271","SJAG_05240","SJAG_03954","SJAG_03995","SJAG_00857","SJAG_02790"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[88086,90787,91069,91724,91767,100504,105902,106721,109953,114731,117538],"is_not":false,"summary":null,"term":"GO:0003727"},{"annotations":[72514,88597,98019,74188,91442,89000,97045,107189,103786,108665,96616,88961],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008143"},{"annotations":[72519,74193,98020,107190,114382,115855,89001,95332,95130,105817,94662,109396,96617,112334],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008266"},{"annotations":[102694],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008187"},{"annotations":[105085,109005,71220,106777],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033592"},{"annotations":[71221,105086,109006],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034057"}]},"cv_name":"molecular_function","definition":"Binding to single-stranded RNA.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA binding","termid":"GO:0003723"}],"gene_count":35,"genes_by_uniquename":{"SJAG_00145":null,"SJAG_00425":null,"SJAG_00857":null,"SJAG_00884":null,"SJAG_01201":null,"SJAG_01222":null,"SJAG_01327":null,"SJAG_01436":null,"SJAG_01643":null,"SJAG_01650":null,"SJAG_01910":null,"SJAG_02043":null,"SJAG_02469":null,"SJAG_02621":null,"SJAG_02790":null,"SJAG_02808":null,"SJAG_03214":null,"SJAG_03283":null,"SJAG_03433":null,"SJAG_03448":null,"SJAG_03460":null,"SJAG_03745":null,"SJAG_03747":null,"SJAG_03876":null,"SJAG_03916":null,"SJAG_03954":null,"SJAG_03995":null,"SJAG_04210":null,"SJAG_04271":null,"SJAG_04427":null,"SJAG_04574":null,"SJAG_04601":null,"SJAG_04880":null,"SJAG_05010":null,"SJAG_05240":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003723","GO:0003674"],"is_obsolete":false,"name":"single-stranded RNA binding","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0003728"],"synonyms":[{"name":"ssRNA binding","type":"exact"}],"termid":"GO:0003727","terms_by_termid":{"GO:0003727":null,"GO:0008143":null,"GO:0008187":null,"GO:0008266":null,"GO:0033592":null,"GO:0034057":null}}


id: GO:0090654
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells.","definition_xrefs":["PMID:11389442","PMID:17494872","PMID:21170358","PMID:9405315","PMID:16394106"],"direct_ancestors":[{"relation_name":"is_a","term_name":"recycling endosome","termid":"GO:0055037"},{"relation_name":"part_of","term_name":"basolateral cytoplasm","termid":"GO:0090652"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005768"}],"interesting_parent_ids":["GO:0031410","GO:0005575","GO:0005737","GO:0005768"],"is_obsolete":false,"name":"basolateral recycling endosome","termid":"GO:0090654"}


id: MONDO:0005056
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Squamous cell carcinomas with morphologically prominent production of keratin.","definition_xrefs":["NCIT:C4105"],"direct_ancestors":[{"relation_name":"is_a","term_name":"squamous cell carcinoma","termid":"MONDO:0005096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"keratinizing squamous cell carcinoma","secondary_identifiers":["ICDO:8071/3","DOID:5521","MEDGEN:137730","UMLS:C0334247","EFO:0000559"],"synonyms":[{"name":"keratinizing epidermoid carcinoma","type":"exact"},{"name":"keratinizing squamous cell carcinoma","type":"exact"},{"name":"squamous cell carcinoma, keratinizing","type":"exact"},{"name":"squamous cell carcinoma, keratinizing (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0005056","xrefs":{"Monarch":{"xref_id":"0005056"}}}


id: GO:0033331
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.","definition_xrefs":["GOC:mah","PMID:17064690"],"direct_ancestors":[{"relation_name":"is_a","term_name":"terpene metabolic process","termid":"GO:0042214"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"ent-kaurene metabolic process","synonyms":[{"name":"ent-kaurene metabolism","type":"exact"}],"termid":"GO:0033331"}


id: FYPO:0003643
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of urease activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal urease activity","termid":"FYPO:0003642"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000707","FYPO:0000661","FYPO:0000652","FYPO:0000654"],"is_obsolete":false,"name":"decreased urease activity","synonyms":[{"name":"reduced urease activity","type":"exact"}],"termid":"FYPO:0003643"}


id: GO:0060178
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of localization","termid":"GO:0032879"},{"relation_name":"regulates","term_name":"exocyst localization","termid":"GO:0051601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of exocyst localization","synonyms":[{"name":"regulation of exocyst localisation","type":"exact"}],"termid":"GO:0060178"}


id: GO:0040001
data:
  {"annotated_genes":["SJAG_02695","SJAG_00140","SJAG_02737"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75937,96479,116387],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000132"}]},"cv_name":"biological_process","definition":"The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of spindle localization","termid":"GO:0051293"},{"relation_name":"is_a","term_name":"microtubule cytoskeleton organization involved in mitosis","termid":"GO:1902850"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00140":null,"SJAG_02695":null,"SJAG_02737":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0000226"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0000226","GO:0007010","GO:0007049"],"is_obsolete":false,"name":"establishment of mitotic spindle localization","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0030608","GO:0018986","GO:0030610","GO:0030606","GO:0030605"],"synonyms":[{"name":"establishment of mitotic spindle localisation","type":"exact"},{"name":"mitotic spindle positioning","type":"exact"},{"name":"mitotic spindle positioning and orientation","type":"narrow"},{"name":"mitotic spindle positioning or orientation","type":"exact"},{"name":"spindle positioning during mitosis","type":"related"},{"name":"spindle positioning involved in mitotic cell cycle","type":"exact"}],"termid":"GO:0040001","terms_by_termid":{"GO:0000132":null}}


id: MONDO:0859372
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cardiomyopathy, familial hypertrophic, 29, with polyglucosan bodies","secondary_identifiers":["MEDGEN:1824081","UMLS:C5774308","OMIM:620236"],"termid":"MONDO:0859372","xrefs":{"Monarch":{"xref_id":"0859372"}}}


id: MONDO:0019758
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Midline interhemispheric variant of holoprosencephaly (MIH) or syntelencephaly is a form of holoprosencephaly (HPE) characterized by non-separation of the posterior frontal and parietal lobes, normally-formed callosal genu and splenium, absence of the callosal body, normally-separated hypothalamus and lentiform nucleus, and frequent heterotopic gray matter.","definition_xrefs":["Orphanet:93926"],"gene_count":0,"genotype_count":0,"name":"obsolete midline interhemispheric variant of holoprosencephaly (obsolete MONDO:0019758)","synonyms":[{"name":"MIH","type":"exact"},{"name":"MIH type HPE","type":"exact"},{"name":"MIHF","type":"exact"},{"name":"MIHV","type":"exact"},{"name":"Syntelencephaly","type":"exact"},{"name":"middle interhemispheric fusion variant","type":"exact"},{"name":"middle interhemispheric variant of holoprosencephaly","type":"exact"}],"termid":"MONDO:0019758","xrefs":{"Monarch":{"xref_id":"0019758"}}}


id: FYPO:0004675
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing dimethyl sulfoxide.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002060"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0002058","FYPO:0002060","FYPO:0000139","FYPO:0000003","FYPO:0002057"],"is_obsolete":false,"name":"normal growth on dimethyl sulfoxide","synonyms":[{"name":"normal cell population growth in presence of dimethyl sulfoxide","type":"exact"},{"name":"normal cell population growth on DMSO","type":"exact"},{"name":"normal cell population growth on dimethyl sulfoxide","type":"exact"},{"name":"normal cellular response to dimethyl sulfoxide","type":"related"},{"name":"normal growth on dimethyl sulphoxide","type":"exact"},{"name":"normal vegetative cell population growth on dimethyl sulfoxide","type":"exact"}],"termid":"FYPO:0004675"}


id: MONDO:0054665
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated pituitary adenoma","termid":"MONDO:0017824"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pituitary adenoma 3, multiple types","secondary_identifiers":["MEDGEN:1620824","DOID:0112010","UMLS:C4540135","OMIM:617686"],"synonyms":[{"name":"PITA3","type":"related"},{"name":"pituitary adenoma 3, multiple types","type":"exact"},{"name":"pituitary adenoma 3, multiple types, somatic","type":"exact"}],"termid":"MONDO:0054665","xrefs":{"Monarch":{"xref_id":"0054665"}}}


id: PBO:0040760
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beclin 1","termid":"PBO:0040760"}


id: PBO:0043631
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COPB2 divergent transcript","termid":"PBO:0043631"}


id: GO:0030158
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.","definition_xrefs":["EC:2.4.2.26"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-xylosyltransferase activity","termid":"GO:0035252"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a protein","termid":"GO:0140096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016757"}],"interesting_parent_ids":["GO:0003824","GO:0140096","GO:0003674","GO:0016757","GO:0016740"],"is_obsolete":false,"name":"protein xylosyltransferase activity","secondary_identifiers":["MetaCyc:2.4.2.26-RXN","Reactome:R-HSA-1878002","RHEA:50192"],"synonyms":[{"name":"UDP-D-xylose:core protein beta-D-xylosyltransferase activity","type":"related"},{"name":"UDP-D-xylose:core protein xylosyltransferase activity","type":"related"},{"name":"UDP-D-xylose:protein beta-D-xylosyltransferase activity","type":"related"},{"name":"UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity","type":"related"},{"name":"UDP-xylose-core protein beta-D-xylosyltransferase activity","type":"related"},{"name":"peptide O-xylosyltransferase activity","type":"exact"},{"name":"uridine diphosphoxylose-core protein beta-xylosyltransferase activity","type":"related"},{"name":"uridine diphosphoxylose-protein xylosyltransferase activity","type":"related"}],"termid":"GO:0030158"}


id: GO:0046525
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.","definition_xrefs":["EC:2.4.1.133"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-galactosyltransferase activity","termid":"GO:0035250"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a glycoprotein","termid":"GO:0140103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0016757","GO:0003824","GO:0140096"],"is_obsolete":false,"name":"xylosylprotein 4-beta-galactosyltransferase activity","secondary_identifiers":["MetaCyc:2.4.1.133-RXN","Reactome:R-HSA-1889981","Reactome:R-HSA-3560804","RHEA:15297"],"synonyms":[{"name":"UDP-D-galactose:D-xylose galactosyltransferase activity","type":"related"},{"name":"UDP-D-galactose:xylose galactosyltransferase activity","type":"related"},{"name":"UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity","type":"related"},{"name":"UDP-galactose:xylose galactosyltransferase activity","type":"exact"},{"name":"UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity","type":"related"},{"name":"galactosyltransferase I activity","type":"related"},{"name":"uridine diphosphogalactose-xylose galactosyltransferase activity","type":"related"}],"termid":"GO:0046525"}


id: MONDO:0020820
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"Sheldon-hall syndrome","termid":"MONDO:0011128"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"distal arthrogryposis type 2B1","secondary_identifiers":["UMLS:C5193014","GARD:9909","DOID:0111600","MEDGEN:1676961","OMIM:601680"],"synonyms":[{"name":"DA2B1","type":"exact"},{"name":"arthrogryposis, distal, type 2B1","type":"exact"}],"termid":"MONDO:0020820","xrefs":{"Monarch":{"xref_id":"0020820"}}}


id: PR:Q9UR09
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- psu1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UR09"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"secreted beta-glucosidase PSU1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.13c","synonyms":[{"name":"Spom972h-psu1","type":"exact"},{"name":"cell wall synthesis protein psu1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UR09"}


id: GO:0000199
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.","definition_xrefs":["PMID:9561267"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of MAPK activity involved in cell wall organization or biogenesis (obsolete GO:0000199)","synonyms":[{"name":"activation of MAPK activity involved in cell wall biogenesis","type":"narrow"},{"name":"activation of MAPK activity involved in cell wall integrity","type":"exact"},{"name":"cell wall biogenesis, activation of MAPK activity","type":"exact"}],"termid":"GO:0000199"}


id: GO:0031276
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.","definition_xrefs":["GOC:dph","GOC:tb","GOC:pg"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of lateral pseudopodium assembly (obsolete GO:0031276)","synonyms":[{"name":"down regulation of lateral pseudopodium formation","type":"related"},{"name":"down-regulation of lateral pseudopodium formation","type":"related"},{"name":"downregulation of lateral pseudopodium formation","type":"related"},{"name":"inhibition of lateral pseudopodium formation","type":"narrow"},{"name":"negative regulation of lateral pseudopodium formation","type":"related"}],"termid":"GO:0031276"}


id: GO:0060748
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.","definition_xrefs":["GOC:dph","PMID:18614704"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"part_of","term_name":"mammary gland branching involved in pregnancy","termid":"GO:0060745"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tertiary branching involved in mammary gland duct morphogenesis","termid":"GO:0060748"}


id: MONDO:0020556
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A pleuropulmonary blastoma composed of malignant small cells and characterized by the presence of a sarcomatous component. It usually follows an aggressive clinical course.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pleuropulmonary blastoma","termid":"MONDO:0011014"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"pleuropulmonary blastoma type 2","secondary_identifiers":["Orphanet:99934","ICD9:162.9","MEDGEN:328133","SCTID:707672001","UMLS:C1710500","NCIT:C45627","GARD:19716"],"synonyms":[{"name":"type II pleuropulmonary blastoma","type":"exact"}],"termid":"MONDO:0020556","xrefs":{"Monarch":{"xref_id":"0020556"}}}


id: PR:O59722
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fab1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O59722"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1-phosphatidylinositol 3-phosphate 5-kinase fab1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC3E7.01","synonyms":[{"name":"PIPkin-III (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-fab1","type":"exact"},{"name":"diphosphoinositide kinase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"phosphatidylinositol 3-phosphate 5-kinase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"type III PIP kinase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O59722"}


id: GO:0008352
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).","definition_xrefs":["PMID:10910766"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule associated complex","termid":"GO:0005875"},{"relation_name":"part_of","term_name":"microtubule organizing center","termid":"GO:0005815"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0005575","GO:0015630","GO:0032991"],"is_obsolete":false,"name":"katanin complex","termid":"GO:0008352"}


id: GO:1904837
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.","definition_xrefs":["PMID:18936100","GO_REF:0000079","GOC:bf","GOC:PARL","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0008150","GO:0065003","GO:0044085"],"is_obsolete":false,"name":"beta-catenin-TCF complex assembly","secondary_identifiers":["Reactome:R-HSA-201722"],"synonyms":[{"name":"beta-catenin-TCF complex formation","type":"exact"},{"name":"beta-catenin/LEF complex assembly","type":"narrow"},{"name":"beta-catenin/LEF complex formation","type":"narrow"},{"name":"beta-catenin/T-cell factor complex assembly","type":"related"},{"name":"beta-catenin/T-cell factor complex formation","type":"related"},{"name":"beta-catenin/lymphoid enhancer binding factor complex assembly","type":"related"},{"name":"beta-catenin/lymphoid enhancer binding factor complex formation","type":"related"}],"termid":"GO:1904837"}


id: MONDO:0015241
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Arthrogryposis-like syndrome, also known as Kuskokwim disease, is a very rare congenital contracture disorder, reported exclusively in Yup'ik Eskimos of the Kuskokwim River delta region of Alaska, characterized by multiple contractures of large joints (predominantly the knees and ankles) that present at birth or during childhood but are lifelong; deformities of the spine, pelvis and feet; and sometimes proximally or distally displaced patellae and muscle atrophy in the limbs with contractures. Additional radiological features include mild vertebral wedging, elongation of the vertebral pedicle, and clubbing of the distal clavicle. An autosomal recessive pattern of inheritance has been suggested.","definition_xrefs":["Orphanet:1149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arthrogryposis multiplex congenita","termid":"MONDO:0015168"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis-like syndrome","secondary_identifiers":["SCTID:702447002","UMLS:C1859709","GARD:3150","ICD9:719.89","MEDGEN:349229","OMIM:208200"],"synonyms":[{"name":"Kuskokwim disease","type":"exact"},{"name":"Kuskokwim syndrome","type":"related"},{"name":"arthrogryposis like disorder","type":"related"}],"termid":"MONDO:0015241","xrefs":{"Monarch":{"xref_id":"0015241"}}}


id: PBO:0067896
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 198","termid":"PBO:0067896"}


id: MONDO:0850301
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autoimmune disease of skin and connective tissue that is characterized by subepidermal blistering especially in the lower abdomen, groin, and flexor surfaces of the extremities, creating tense blisters that do not break easily.","definition_xrefs":["DOID:0080841"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune bullous skin disease","termid":"MONDO:0019337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005093"],"is_obsolete":false,"name":"pemphigoid","secondary_identifiers":["SCTID:86142006","icd11.foundation:445309625"],"termid":"MONDO:0850301","xrefs":{"Monarch":{"xref_id":"0850301"}}}


id: GO:1901648
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of actomyosin contractile ring localization.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of actomyosin contractile ring localization (obsolete GO:1901648)","synonyms":[{"name":"regulation of contractile ring localisation involved in cell cycle cytokinesis","type":"exact"},{"name":"regulation of contractile ring localization involved in cell cycle cytokinesis","type":"exact"}],"termid":"GO:1901648"}


id: PBO:0069037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 282, pseudogene","termid":"PBO:0069037"}


id: PBO:0050991
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intraflagellar transport 81","termid":"PBO:0050991"}


id: PBO:0052454
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLF transcription factor 5","termid":"PBO:0052454"}


id: PBO:0084276
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Integral membrane protein involved in GPI anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the glycosylphosphatidylinositol (GPI) core structure; human PIG-Bp is a functional homolog","termid":"PBO:0084276"}


id: PBO:0089447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleobase cation symporter family","termid":"PBO:0089447"}


id: MONDO:0019802
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Secondary short bowel syndrome is an intestinal failure caused by any condition that results in a functional small intestine of less than 200 cm in length and is characterized by diarrhea, nutrient malabsoption, bowel dilation and dysmobility.","definition_xrefs":["Orphanet:95427"],"direct_ancestors":[{"relation_name":"is_a","term_name":"short bowel syndrome","termid":"MONDO:0015183"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"secondary short bowel syndrome","secondary_identifiers":["GARD:19258","MEDGEN:1842747","UMLS:C5681579"],"termid":"MONDO:0019802","xrefs":{"Monarch":{"xref_id":"0019802"}}}


id: MONDO:0011300
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"myopia","termid":"MONDO:0001384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"myopia 3, autosomal dominant","secondary_identifiers":["MEDGEN:400454","MESH:C566397","OMIM:603221","UMLS:C1864111"],"synonyms":[{"name":"MYP3","type":"exact"},{"name":"myopia 3, autosomal dominant","type":"exact"},{"name":"myopia-3","type":"exact"}],"termid":"MONDO:0011300","xrefs":{"Monarch":{"xref_id":"0011300"}}}


id: PBO:0002971
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"multidomain vesicle coat component Sec16 (predicted)","termid":"PBO:0002971"}


id: PBO:0076113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"STX18 antisense RNA 1 (head to head)","termid":"PBO:0076113"}


id: PBO:0044718
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEAD/H-box helicase 11 like 5 (pseudogene)","termid":"PBO:0044718"}


id: _global:present_during
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD_extension_relations","definition":"Identifies a biological phase or process during which the modification is observed, where it is not known whether the modification was added during the indicated phase or process (if this is known use the added_during relation) or during a preceding phase or process.","definition_xrefs":["PomBase:al"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"present_during","termid":"_global:present_during"}


id: PBO:0088148
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium; protein abundance increases in response to DNA replication stress; COT1 has a paralog, ZRC1, that arose from the whole genome duplication","termid":"PBO:0088148"}


id: PBO:0084184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Histone deacetylase, component of both the Rpd3S and Rpd3L complexes; regulates transcription, silencing, autophagy and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members; Rpd3(L) recruitment to the subtelomeric region is regulated by interaction with the arginine methyltransferase, Hmt1p","termid":"PBO:0084184"}


id: GO:0034751
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.","definition_xrefs":["GOC:mah","PMID:7598497"],"direct_ancestors":[{"relation_name":"is_a","term_name":"receptor complex","termid":"GO:0043235"},{"relation_name":"is_a","term_name":"intracellular protein-containing complex","termid":"GO:0140535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"aryl hydrocarbon receptor complex","synonyms":[{"name":"AHRC","type":"exact"},{"name":"AhR complex","type":"exact"}],"termid":"GO:0034751"}


id: MONDO:1010325
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital nystagmus that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder, non-human animal","termid":"MONDO:1011308"},{"relation_name":"is_a","term_name":"hereditary neurological disease, non-human animal","termid":"MONDO:1012972"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital nystagmus, non-human animal","secondary_identifiers":["OMIA:000731"],"termid":"MONDO:1010325","xrefs":{"Monarch":{"xref_id":"1010325"}}}


id: PBO:0070813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 43","termid":"PBO:0070813"}


id: GO:0047539
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.","definition_xrefs":["MetaCyc:2-DEOXYGLUCOSIDASE-RXN","EC:3.2.1.112"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucosidase activity","termid":"GO:0015926"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824","GO:0016798"],"is_obsolete":false,"name":"2-deoxyglucosidase activity","secondary_identifiers":["RHEA:15317"],"synonyms":[{"name":"2-deoxy-alpha-D-glucosidase activity","type":"related"},{"name":"2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity","type":"related"},{"name":"2-deoxy-alpha-glucosidase activity","type":"related"}],"termid":"GO:0047539"}


id: MONDO:0017681
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete erythrokeratoderma variabilis progressiva (obsolete MONDO:0017681)","termid":"MONDO:0017681","xrefs":{"Monarch":{"xref_id":"0017681"}}}


id: GO:0016085
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.","definition_xrefs":["GOC:mah","PMID:8902848"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hormone activity","termid":"GO:0005179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0140677"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0140677","GO:0098772","GO:0005488"],"is_obsolete":false,"name":"myoinhibitory hormone activity","termid":"GO:0016085"}


id: GO:0031168
data:
  {"annotated_genes":["SJAG_04032","SJAG_04031","SJAG_00792"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[93618,93610],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031169"},{"annotations":[93564],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:1905569"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.","definition_xrefs":["ISBN:0198506732","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"siderophore metabolic process","termid":"GO:0009237"},{"relation_name":"is_a","term_name":"amide metabolic process","termid":"GO:0043603"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00792":null,"SJAG_04031":null,"SJAG_04032":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"ferrichrome metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"ferrichrome metabolism","type":"exact"}],"termid":"GO:0031168","terms_by_termid":{"GO:0031169":null,"GO:1905569":null}}


id: GO:0044488
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.","definition_xrefs":["GOC:jl","GOC:fj","PMID:21781281"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modulation of ion channel activity in another organism","termid":"GO:0044561"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"modulation of voltage-gated sodium channel activity in another organism","synonyms":[{"name":"modulation of voltage-gated sodium channel activity in other organism","type":"exact"}],"termid":"GO:0044488"}


id: FYPO:0006771
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which a cell has actin cortical patches in one or more abnormal locations.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular physical quality phenotype","termid":"FYPO:0000136"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002"],"is_obsolete":false,"name":"mislocalized actin cortical patches","synonyms":[{"name":"abnormal actin cortical patch location","type":"exact"},{"name":"abnormal actin cortical patch position","type":"exact"},{"name":"mislocalised actin cortical patches","type":"exact"},{"name":"mislocalized F-actin patches","type":"exact"},{"name":"mislocalized actin patches","type":"exact"}],"termid":"FYPO:0006771"}


id: PBO:0045300
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynamin 2","termid":"PBO:0045300"}


id: PBO:0040504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activator of transcription and developmental regulator AUTS2","termid":"PBO:0040504"}


