# terms

id: GO:0005461
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.","definition_xrefs":["ISBN:0815340729","GOC:mtg_transport","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine nucleotide-sugar transmembrane transporter activity","termid":"GO:0015165"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transporter activity","termid":"GO:0046943"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"UDP-glucuronate transmembrane transporter activity","secondary_identifiers":["Reactome:R-HSA-174368","Reactome:R-HSA-5603297","Reactome:R-HSA-9912889"],"synonyms":[{"name":"UDP-glucuronic acid transmembrane transporter activity","type":"exact"}],"termid":"GO:0005461"}


id: PBO:0040244
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy related 3 pseudogene 1","termid":"PBO:0040244"}


id: PBO:0028278
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-merotelic_kinetochore_attachment_during_mitosis","termid":"PBO:0028278"}


id: GO:0018069
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase.","definition_xrefs":["RESID:AA0149"],"gene_count":0,"genotype_count":0,"name":"obsolete peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone (obsolete GO:0018069)","termid":"GO:0018069"}


id: GO:0085035
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell projection","termid":"GO:0042995"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"haustorium","termid":"GO:0085035"}


id: PBO:0050691
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 8 pseudogene 18","termid":"PBO:0050691"}


id: PBO:0070641
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7 pseudogene 12","termid":"PBO:0070641"}


id: MONDO:0013224
data:
  {"annotated_genes":["SJAG_05313","SJAG_04755"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87079,87080],"is_not":false,"summary":null,"term":"MONDO:0013224"}]},"cv_name":"mondo","definition":"Any familial rhabdoid tumor in which the cause of the disease is a mutation in the SMARCA4 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial rhabdoid tumor","termid":"MONDO:0016473"},{"relation_name":"is_a","term_name":"atypical teratoid rhabdoid tumor","termid":"MONDO:0020560"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04755":null,"SJAG_05313":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"rhabdoid tumor predisposition syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C178394","UMLS:C2750074","GARD:18319","OMIM:613325","MEDGEN:413749","MESH:C567643"],"synonyms":[{"name":"RTPS2","type":"related"},{"name":"SMARCA4 familial rhabdoid tumor","type":"exact"},{"name":"SMARCA4 familial rhabdoid tumour","type":"exact"},{"name":"familial rhabdoid tumor caused by mutation in SMARCA4","type":"exact"},{"name":"familial rhabdoid tumour caused by mutation in SMARCA4","type":"exact"},{"name":"rhabdoid tumor predisposition syndrome 2","type":"exact"},{"name":"rhabdoid tumor predisposition syndrome type 2","type":"exact"},{"name":"rhabdoid tumour predisposition syndrome type 2","type":"exact"}],"termid":"MONDO:0013224","terms_by_termid":{"MONDO:0013224":null},"xrefs":{"Monarch":{"xref_id":"0013224"}}}


id: PBO:0036183
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_histone_H3-K9_methylation_at_centromere_outer_repeat_during_vegetative_growth","termid":"PBO:0036183"}


id: PBO:0015709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteinase B inhibitor Pbi2","termid":"PBO:0015709"}


id: PBO:0078791
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Asn (GTT) 14-1","termid":"PBO:0078791"}


id: PBO:0057924
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3649","termid":"PBO:0057924"}


id: MONDO:0031329
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome","secondary_identifiers":["OMIMPS:213980","DOID:0081072"],"termid":"MONDO:0031329","xrefs":{"Monarch":{"xref_id":"0031329"}}}


id: MONDO:0019466
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Lymphomatoid granulomatosis (LYG) is a very rare Epstein-Barr virus (EBV)-driven lymphoproliferative disease most commonly occurring in adults (in the fourth to sixth decade of life) and commonly affecting the lungs (with presentations varying from small bilateral pulmonary nodules to large necrotic and sometimes cavitating lesions), skin, central nervous system, and kidneys, but only very rarely affecting the lymph nodes and spleen. The symptoms associated with LYG depend on the site of disease involvement but mainly include cough, dyspnea or chest pain (in those with pulmonary involvement) and constitutional symptoms such as weight loss and fever.","definition_xrefs":["Orphanet:86869"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Epstein-Barr virus-associated malignant lymphoproliferative disorder","termid":"MONDO:0017343"},{"relation_name":"is_a","term_name":"diffuse large B-cell lymphoma","termid":"MONDO:0018905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"lymphomatoid granulomatosis","secondary_identifiers":["MedDRA:10025325","GARD:6943","MESH:D008230","icd11.foundation:1890408959","NORD:1385","ICDO:9766/1","MEDGEN:6161","SCTID:239940004","ONCOTREE:LYG","DOID:0081307","NCIT:C7930","UMLS:C0024307"],"synonyms":[{"name":"LYG","type":"exact"}],"termid":"MONDO:0019466","xrefs":{"Monarch":{"xref_id":"0019466"}}}


id: PBO:0000605
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G-patch domain","termid":"PBO:0000605"}


id: GO:0046697
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.","definition_xrefs":["ISBN:0721662544","PMID:11133685"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"is_a","term_name":"tissue development","termid":"GO:0009888"},{"relation_name":"part_of","term_name":"maternal placenta development","termid":"GO:0001893"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"decidualization","secondary_identifiers":["Wikipedia:Decidualization"],"synonyms":[{"name":"decidual cell reaction","type":"exact"}],"termid":"GO:0046697"}


id: GO:0008773
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).","definition_xrefs":["EC:2.7.7.59"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uridylyltransferase activity","termid":"GO:0070569"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a protein","termid":"GO:0140096"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016779"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140096","GO:0016740","GO:0003824","GO:0016779","GO:0003674"],"is_obsolete":false,"name":"[protein-PII] uridylyltransferase activity","secondary_identifiers":["MetaCyc:URITRANS-RXN","RHEA:13673"],"synonyms":[{"name":"PII uridylyl-transferase activity","type":"related"},{"name":"UTP:[protein-PII] uridylyltransferase activity","type":"exact"},{"name":"UTP:protein-PII uridylyltransferase activity","type":"related"},{"name":"protein-PII uridylyltransferase activity","type":"related"},{"name":"uridyl removing enzyme","type":"related"},{"name":"uridylyl removing enzyme activity","type":"broad"}],"termid":"GO:0008773"}


id: MONDO:0100269
data:
  {"annotated_genes":["SJAG_03440"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86984],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013942"},{"annotations":[86982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013943"}]},"cv_name":"mondo","definition":"Any Zellweger spectrum disorder in which the cause of the disease is a mutation in the PEX16 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Zellweger spectrum disorders","termid":"MONDO:0019609"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03440":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019053"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0019053","MONDO:0005066","MONDO:0005244","MONDO:0005559","MONDO:0006025"],"is_obsolete":false,"name":"peroxisome biogenesis disorder due to PEX16 defect","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"PEX16 related Zellweger spectrum disorder","type":"exact"},{"name":"peroxisome biogenesis disorder due to PEX16 defect","type":"exact"}],"termid":"MONDO:0100269","terms_by_termid":{"MONDO:0013942":null,"MONDO:0013943":null},"xrefs":{"Monarch":{"xref_id":"0100269"}}}


id: MONDO:0006908
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, potentially life-threatening disorder caused by acute ischemic infarction or hemorrhage in the pituitary gland. It is most often associated with the presence of a pituitary gland adenoma. Signs and symptoms include headache, vomiting, visual disturbances, and endocrine dysfunction.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pituitary gland infarction","termid":"MONDO:0001259"},{"relation_name":"is_a","term_name":"acquired pituitary hormone deficiency","termid":"MONDO:0019832"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pituitary apoplexy","secondary_identifiers":["MESH:D010899","ICD9:253.8","MEDGEN:18489","SCTID:237701005","GARD:19287","MedDRA:10056447","UMLS:C0032001","DOID:1129","EFO:1001108","icd11.foundation:1938573221","NCIT:C26853","Orphanet:95613"],"synonyms":[{"name":"pituitary gland apoplexy","type":"exact"}],"termid":"MONDO:0006908","xrefs":{"Monarch":{"xref_id":"0006908"}}}


id: PBO:0040098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)","termid":"PBO:0040098"}


id: PBO:0051679
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"INHBA antisense RNA 1","termid":"PBO:0051679"}


id: FYPO:0002514
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the palmitoylation of one or more specific proteins is abnormal during one or both meiotic nuclear divisions.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein palmitoylation","termid":"FYPO:0002503"},{"relation_name":"is_a","term_name":"abnormal protein modification during meiotic cell cycle","termid":"FYPO:0006459"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002274","FYPO:0005447","FYPO:0000002","FYPO:0002494"],"is_obsolete":false,"name":"abnormal protein palmitoylation during meiosis","synonyms":[{"name":"abnormal protein palmitoylation during meiotic nuclear division","type":"exact"}],"termid":"FYPO:0002514"}


id: PBO:0004954
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aldo/keto reductase involved in pentose catabolism (predicted)","termid":"PBO:0004954"}


id: PBO:0085745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in vesicular transport at trans-Golgi network (TGN); TGN-localized, leucine-zipper domain protein; involved in endosome-to-Golgi transport during endocytic recycling, and retrograde transport of glycosyltransferases from the TGN to the Golgi; involved in organization of the ER, establishment of cell polarity, and morphogenesis; detected in highly purified mitochondria in high-throughput studies","termid":"PBO:0085745"}


id: GO:0061155
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.","definition_xrefs":["GOC:yaf","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endothelial tube morphogenesis","termid":"GO:0061154"},{"relation_name":"part_of","term_name":"pulmonary artery morphogenesis","termid":"GO:0061156"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pulmonary artery endothelial tube morphogenesis","termid":"GO:0061155"}


id: MONDO:0015560
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete classic mast cell leukemia (obsolete MONDO:0015560)","secondary_identifiers":["Orphanet:158796"],"termid":"MONDO:0015560","xrefs":{"Monarch":{"xref_id":"0015560"}}}


id: PBO:0046526
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endoplasmic reticulum oxidoreductase 1 alpha","termid":"PBO:0046526"}


id: PBO:0053357
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 261","termid":"PBO:0053357"}


id: GO:0001733
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.","definition_xrefs":["RHEA:20613","EC:2.8.2.11","PMID:10727929"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactose 3-O-sulfotransferase activity","termid":"GO:0050694"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016782"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0016782","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"galactosylceramide sulfotransferase activity","secondary_identifiers":["MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN","Reactome:R-HSA-9844587"],"synonyms":[{"name":"3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity","type":"related"},{"name":"3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity","type":"related"},{"name":"GSase","type":"related"},{"name":"cerebroside sulfotransferase activity","type":"exact"},{"name":"galactocerebroside sulfotransferase activity","type":"related"},{"name":"galactolipid sulfotransferase activity","type":"related"},{"name":"galactosylceramide sulphotransferase activity","type":"exact"},{"name":"glycolipid sulfotransferase activity","type":"related"},{"name":"glycosphingolipid sulfotransferase activity","type":"related"}],"termid":"GO:0001733"}


id: GO:0075202
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of anatomical structure morphogenesis","termid":"GO:0022603"},{"relation_name":"is_a","term_name":"modulation of formation of structure involved in a symbiotic process","termid":"GO:0044145"},{"relation_name":"is_a","term_name":"modulation by symbiont of entry into host","termid":"GO:0052372"},{"relation_name":"regulates","term_name":"penetration hypha formation","termid":"GO:0075201"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of penetration hypha formation","synonyms":[{"name":"modulation of symbiont penetration hypha formation for entry into host","type":"exact"}],"termid":"GO:0075202"}


id: GO:0055044
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata.","definition_xrefs":["GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"symplast","secondary_identifiers":["Wikipedia:Symplast"],"termid":"GO:0055044"}


id: PR:Q9US00
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- amt2 gene.","definition_xrefs":["UniProtKB:Q9US00","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ammonium transporter 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC664.14","synonyms":[{"name":"Spom972h-amt2","type":"exact"}],"termid":"PR:Q9US00"}


id: PBO:0071468
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L32 pseudogene 9","termid":"PBO:0071468"}


id: PATO:0001451
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An extended swelling in plant organs caused primarily by an excessive accumulation of water.","definition_xrefs":["thefreedictionary.com:thefreedictionary.com"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001451 edematous (sensu botany) (obsolete PATO:0001451)","synonyms":[{"name":"edemic","type":"exact"},{"name":"oedematous","type":"exact"},{"name":"oedemic","type":"exact"}],"termid":"PATO:0001451"}


id: GO:0033566
data:
  {"annotated_genes":["SJAG_01756"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[116998],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990735"}]},"cv_name":"biological_process","definition":"Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex localization","termid":"GO:0031503"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01756":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"gamma-tubulin complex localization","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"establishment and maintenance of gamma-tubulin complex localization","type":"exact"},{"name":"gamma-tubulin complex localisation","type":"exact"}],"termid":"GO:0033566","terms_by_termid":{"GO:1990735":null}}


id: PBO:0018039
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae INP51 INP52 INP53 triple mutant","termid":"PBO:0018039"}


id: FYPO:0008036
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at the CENP-A boundary. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes.","definition_xrefs":["PMID:36200823"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased nucleosome occupancy","termid":"FYPO:0007655"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000641","FYPO:0005447","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased nucleosome occupancy at CENP-A boundary","termid":"FYPO:0008036"}


id: PBO:0013448
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"soluble Myh1 level decreases in presence of cisplatin or hydrogen peroxide","termid":"PBO:0013448"}


id: GO:0071543
data:
  {"annotated_genes":["SJAG_04870","SJAG_01154"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[78949,104992],"is_not":false,"summary":null,"term":"GO:0071543"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.","definition_xrefs":["GOC:mah","PMID:12387729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inositol phosphate metabolic process","termid":"GO:0043647"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01154":null,"SJAG_04870":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"diphosphoinositol polyphosphate metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"diphosphoinositol polyphosphate metabolism","type":"exact"}],"termid":"GO:0071543","terms_by_termid":{"GO:0071543":null}}


id: PBO:0048918
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A8 family member N","termid":"PBO:0048918"}


id: PBO:0113492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcription factor involved in sulfite metabolism; activates transcription of SSU1, DDI2, DDI3; overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers; protein abundance increases in response to DNA replication stress","termid":"PBO:0113492"}


id: MONDO:0035824
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLHL7-related cold-induced sweating-like syndrome","secondary_identifiers":["MEDGEN:1842368","GARD:22437","UMLS:C5680211","Orphanet:603694"],"synonyms":[{"name":"KLHL7-related Crisponi-like syndrome","type":"exact"}],"termid":"MONDO:0035824","xrefs":{"Monarch":{"xref_id":"0035824"}}}


id: GO:0047938
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.","definition_xrefs":["MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN","EC:5.1.3.15"],"direct_ancestors":[{"relation_name":"is_a","term_name":"racemase and epimerase activity, acting on carbohydrates and derivatives","termid":"GO:0016857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016853","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"glucose-6-phosphate 1-epimerase activity","secondary_identifiers":["RHEA:16249"],"synonyms":[{"name":"D-glucose-6-phosphate 1-epimerase activity","type":"related"},{"name":"glucose-6 phosphate 1-epimerase activity","type":"exact"}],"termid":"GO:0047938"}


id: GO:0003234
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiac chamber formation","termid":"GO:0003207"},{"relation_name":"part_of","term_name":"bulbus arteriosus morphogenesis","termid":"GO:0003233"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"bulbus arteriosus formation","termid":"GO:0003234"}


id: MONDO:0014923
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any peeling skin syndrome in which the cause of the disease is a mutation in the SERPINB8 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"exfoliative ichthyosis","termid":"MONDO:0017339"},{"relation_name":"is_a","term_name":"peeling skin syndrome","termid":"MONDO:0019347"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"peeling skin syndrome 5","secondary_identifiers":["GARD:18427","DOID:0070524","MEDGEN:934677","OMIM:617115","UMLS:C4310710"],"synonyms":[{"name":"PSS5","type":"exact"},{"name":"SERPINB8 peeling skin syndrome","type":"exact"},{"name":"peeling skin syndrome 5","type":"exact"},{"name":"peeling skin syndrome 5; PSS5","type":"exact"},{"name":"peeling skin syndrome caused by mutation in SERPINB8","type":"exact"},{"name":"peeling skin syndrome type 5","type":"exact"}],"termid":"MONDO:0014923","xrefs":{"Monarch":{"xref_id":"0014923"}}}


id: GO:0097128
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.","definition_xrefs":["PMID:15935619","GOC:so"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cyclin-dependent protein kinase holoenzyme complex","termid":"GO:0000307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"cyclin D1-CDK4 complex","termid":"GO:0097128"}


id: PBO:0077599
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane serine protease 11B","termid":"PBO:0077599"}


id: GO:0004655
data:
  {"annotated_genes":["SJAG_01372"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71346],"is_not":false,"summary":null,"term":"GO:0004655"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen.","definition_xrefs":["EC:4.2.1.24","RHEA:24064"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01372":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"porphobilinogen synthase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R00036","Reactome:R-HSA-189439","MetaCyc:PORPHOBILSYNTH-RXN"],"synonyms":[{"name":"5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)","type":"related"},{"name":"5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)","type":"related"},{"name":"5-levulinic acid dehydratase activity","type":"related"},{"name":"aminolevulinate dehydratase activity","type":"exact"},{"name":"aminolevulinic dehydratase activity","type":"related"},{"name":"delta-aminolevulinate dehydratase activity","type":"related"},{"name":"delta-aminolevulinic acid dehydrase activity","type":"related"},{"name":"delta-aminolevulinic acid dehydratase activity","type":"exact"},{"name":"delta-aminolevulinic dehydratase activity","type":"related"}],"termid":"GO:0004655","terms_by_termid":{"GO:0004655":null}}


id: MONDO:0016618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"rheumatoid factor-negative juvenile idiopathic arthritis","termid":"MONDO:0019432"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies","secondary_identifiers":["Orphanet:247861"],"synonyms":[{"name":"juvenile rheumatoid factor-negative polyarthritis without anti-nuclear antibodies","type":"exact"},{"name":"polyarthritis without rheumatoid factor without anti-nuclear antibodies","type":"exact"},{"name":"rheumatoid factor-negative JIA without anti-nuclear antibodies","type":"exact"}],"termid":"MONDO:0016618","xrefs":{"Monarch":{"xref_id":"0016618"}}}


id: PBO:0091905
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Golgi alpha-1,2-galactosyltransferase Gma12","termid":"PBO:0091905"}


id: PBO:0036480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial respiratory chain complex II assembly factor 4 Sdh8 (predicted)","termid":"PBO:0036480"}


id: FYPO:0001587
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization during vegetative growth","termid":"FYPO:0000644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000138","FYPO:0000257","FYPO:0001312","FYPO:0000002"],"is_obsolete":false,"name":"normal protein localization to cell tip during vegetative growth","synonyms":[{"name":"normal protein localisation to cell tip during vegetative growth","type":"exact"},{"name":"normal protein localization to cell end during vegetative growth","type":"exact"},{"name":"normal protein localization to cell tip during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001587"}


id: MONDO:0002927
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant mesenchymal neoplasm composed of spindle-shaped cells. This is a morphologic term which can be applied to a wide range of sarcomas.","definition_xrefs":["NCIT:C27005"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sarcoma","termid":"MONDO:0005089"},{"relation_name":"is_a","term_name":"malignant spindle cell neoplasm","termid":"MONDO:0020663"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"spindle cell sarcoma","secondary_identifiers":["DOID:4235","MEDGEN:64477","ICDO:8801/3","UMLS:C0205945"],"synonyms":[{"name":"spindle cell sarcoma","type":"exact"}],"termid":"MONDO:0002927","xrefs":{"Monarch":{"xref_id":"0002927"}}}


id: PBO:0043874
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CREB3L2 antisense RNA 1","termid":"PBO:0043874"}


id: PBO:0046907
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 27 member B","termid":"PBO:0046907"}


id: PBO:0028238
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-mislocalized_protein","termid":"PBO:0028238"}


id: GO:1903845
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.","definition_xrefs":["GO_REF:0000058","PMID:22269326","GOC:TermGenie","GOC:BHF","GOC:rph","GOC:BHF_miRNA"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular response to growth factor stimulus","termid":"GO:0090288"},{"relation_name":"is_a","term_name":"regulation of cellular response to transforming growth factor beta stimulus","termid":"GO:1903844"},{"relation_name":"negatively_regulates","term_name":"cellular response to transforming growth factor beta stimulus","termid":"GO:0071560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cellular response to transforming growth factor beta stimulus","synonyms":[{"name":"down regulation of cellular response to TGF-beta stimulus","type":"exact"},{"name":"down regulation of cellular response to TGFbeta stimulus","type":"exact"},{"name":"down regulation of cellular response to transforming growth factor beta stimulus","type":"exact"},{"name":"down-regulation of cellular response to TGF-beta stimulus","type":"exact"},{"name":"down-regulation of cellular response to TGFbeta stimulus","type":"exact"},{"name":"down-regulation of cellular response to transforming growth factor beta stimulus","type":"exact"},{"name":"downregulation of cellular response to TGF-beta stimulus","type":"exact"},{"name":"downregulation of cellular response to TGFbeta stimulus","type":"exact"},{"name":"downregulation of cellular response to transforming growth factor beta stimulus","type":"exact"},{"name":"inhibition of cellular response to TGF-beta stimulus","type":"narrow"},{"name":"inhibition of cellular response to TGFbeta stimulus","type":"narrow"},{"name":"inhibition of cellular response to transforming growth factor beta stimulus","type":"narrow"},{"name":"negative regulation of cellular response to TGF-beta stimulus","type":"exact"},{"name":"negative regulation of cellular response to TGFbeta stimulus","type":"exact"}],"termid":"GO:1903845"}


id: MONDO:1012839
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any arthrogryposis multiplex congenita that occurs in pigs due to a mutation in the KIF21A gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arthrogryposis multiplex congenita, pig","termid":"MONDO:1011475"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis multiplex congenita, KIF21A-related, pig","secondary_identifiers":["OMIA:002283-9823"],"termid":"MONDO:1012839","xrefs":{"Monarch":{"xref_id":"1012839"}}}


id: GO:0005357
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.","definition_xrefs":["GOC:mtg_transport"],"gene_count":0,"genotype_count":0,"name":"obsolete constitutive glucose:proton symporter activity (obsolete GO:0005357)","synonyms":[{"name":"constitutive hydrogen/glucose transporter activity","type":"broad"},{"name":"constitutive hydrogen:glucose symporter activity","type":"exact"},{"name":"constitutive hydrogen:glucose transporter activity","type":"broad"}],"termid":"GO:0005357"}


id: FYPO:0003934
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an RNA catabolic process that degrades mRNA encoded in the nucleus does not occur. Total mRNA or a specific mRNA, such as the mRNA transcribed from a gene of interest, may be affected.","definition_xrefs":["PomBase:mah","GO:0000956"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular metabolism phenotype during vegetative growth","termid":"FYPO:0001348"},{"relation_name":"is_a","term_name":"abnormal RNA catabolic process","termid":"FYPO:0003551"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0000294"],"is_obsolete":false,"name":"abolished nuclear mRNA catabolic process","synonyms":[{"name":"abolished nuclear mRNA breakdown","type":"exact"},{"name":"abolished nuclear mRNA catabolic process during mitotic cell cycle","type":"related"},{"name":"abolished nuclear mRNA catabolic process during vegetative growth","type":"exact"},{"name":"abolished nuclear mRNA catabolism","type":"exact"},{"name":"abolished nuclear mRNA degradation","type":"exact"},{"name":"abolished nuclear-transcribed mRNA catabolic process","type":"exact"},{"name":"nuclear mRNA catabolic process abolished","type":"exact"}],"termid":"FYPO:0003934"}


id: GO:0006466
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete protein disulfide-isomerase reaction (obsolete GO:0006466)","synonyms":[{"name":"protein disulfide-isomerase reaction","type":"exact"},{"name":"protein disulphide-isomerase reaction","type":"exact"}],"termid":"GO:0006466"}


id: GO:0140747
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of a non-protein coding gene from a DNA-template.","definition_xrefs":["GOC:pg"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of ncRNA transcription (obsolete GO:0140747)","termid":"GO:0140747"}


id: MONDO:0007916
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Primary intestinal lymphangiectasia (PIL) is a rare intestinal disease characterized by dilated intestinal lacteals which cause lymph leakage into the small bowel lumen. Clinical manifestations include edema related to hypoalbuminemia (protein-losing enteropathy), asthenia, diarrhea, lymphedema and failure to thrive in children.","definition_xrefs":["Orphanet:90362"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal lymphangiectasia","termid":"MONDO:0018178"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"primary intestinal lymphangiectasia","secondary_identifiers":["UMLS:C2931241","MEDGEN:444009","GARD:7873","icd11.foundation:52162548","OMIM:152800","ICD9:457.1","NORD:1609","SCTID:6124009"],"synonyms":[{"name":"Waldmann disease","type":"exact"},{"name":"Waldmann's disease","type":"related"},{"name":"familial Waldmann's disease (type)","type":"related"},{"name":"lymphangiectasia, intestinal","type":"related"},{"name":"primary intestinal lymphangiectasis","type":"related"}],"termid":"MONDO:0007916","xrefs":{"Monarch":{"xref_id":"0007916"}}}


id: PBO:0048066
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ferritin heavy chain 1 pseudogene 15","termid":"PBO:0048066"}


id: PBO:0017762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase assembly protein Rcf1","termid":"PBO:0017762"}


id: SO:0002051
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A promoter whereby activity is induced by the presence or absence of biotic or abiotic factors.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"promoter","termid":"SO:0000167"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inducible_promoter","synonyms":[{"name":"inducible promoter","type":"exact"}],"termid":"SO:0002051"}


id: PBO:0042246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine receptor 8","termid":"PBO:0042246"}


id: MONDO:1010444
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cardiomyopathy that occurs in goat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiomyopathy, non-human animal","termid":"MONDO:1010010"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cardiomyopathy, goat","secondary_identifiers":["OMIA:000160-9925"],"termid":"MONDO:1010444","xrefs":{"Monarch":{"xref_id":"1010444"}}}


id: PBO:0005326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EKC/KEOPS complex subunit Cgi121 (predicted)","termid":"PBO:0005326"}


id: PBO:0079367
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tubulin alpha pseudogene 1","termid":"PBO:0079367"}


id: PBO:0054883
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2297","termid":"PBO:0054883"}


id: PBO:0054014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1344","termid":"PBO:0054014"}


id: PR:Q9Y884
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pek1 gene.","definition_xrefs":["UniProtKB:Q9Y884","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP kinase kinase skh1/pek1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC543.07","synonyms":[{"name":"Spom972h-pek1","type":"exact"}],"termid":"PR:Q9Y884"}


id: PBO:0042075
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 144B, pseudogene","termid":"PBO:0042075"}


id: PR:O74460
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC16C4.16c gene.","definition_xrefs":["UniProtKB:O74460","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C16C4.16c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC16C4.16c","synonyms":[{"name":"Spom972h-SPCC16C4.16c","type":"exact"}],"termid":"PR:O74460"}


id: MONDO:0033374
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0005027"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 65","secondary_identifiers":["OMIM:618008","MEDGEN:1634676","UMLS:C4693925","DOID:0080430","GARD:16283"],"synonyms":[{"name":"DEE65","type":"exact"},{"name":"EIEE65","type":"exact"},{"name":"developmental and epileptic encephalopathy 65","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 65","type":"exact"}],"termid":"MONDO:0033374","xrefs":{"Monarch":{"xref_id":"0033374"}}}


id: PBO:0077676
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TNF superfamily member 4","termid":"PBO:0077676"}


id: PBO:0059725
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO2 pseudogene 33","termid":"PBO:0059725"}


id: PBO:0065375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pregnancy specific beta-1-glycoprotein 3","termid":"PBO:0065375"}


id: PR:O14120
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mvp1 gene.","definition_xrefs":["UniProtKB:O14120","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin mvp1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3A11.06","synonyms":[{"name":"Spom972h-mvp1","type":"exact"}],"termid":"PR:O14120"}


id: GO:0008554
data:
  {"annotated_genes":["SJAG_04167"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73146],"is_not":false,"summary":null,"term":"GO:0008554"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism.","definition_xrefs":["PMID:9224683"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium ion transmembrane transporter activity","termid":"GO:0015081"},{"relation_name":"is_a","term_name":"P-type ion transporter activity","termid":"GO:0015662"},{"relation_name":"is_a","term_name":"ATPase-coupled monoatomic cation transmembrane transporter activity","termid":"GO:0019829"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04167":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"P-type sodium transporter activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["EC:7.2.2.3"],"synonyms":[{"name":"Na(+)-exporting ATPase activity","type":"broad"},{"name":"Na(+)-transporting ATPase activity","type":"broad"},{"name":"Na+-exporting ATPase activity","type":"broad"},{"name":"Na+-transporting ATPase activity","type":"broad"},{"name":"sodium exporting ATPase activity, phosphorylative mechanism","type":"exact"},{"name":"sodium transmembrane transporter activity, phosphorylative mechanism","type":"exact"},{"name":"sodium transport ATPase activity","type":"broad"},{"name":"sodium-exporting ATPase activity","type":"broad"},{"name":"sodium-exporting ATPase activity, phosphorylative mechanism","type":"exact"},{"name":"sodium-translocating P-type ATPase activity","type":"exact"}],"termid":"GO:0008554","terms_by_termid":{"GO:0008554":null}}


id: GO:0046370
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fructose metabolic process","termid":"GO:0006000"},{"relation_name":"is_a","term_name":"hexose biosynthetic process","termid":"GO:0019319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"fructose biosynthetic process","secondary_identifiers":["Reactome:R-HSA-5652227"],"synonyms":[{"name":"fructose anabolism","type":"exact"},{"name":"fructose biosynthesis","type":"exact"},{"name":"fructose formation","type":"exact"},{"name":"fructose synthesis","type":"exact"}],"termid":"GO:0046370"}


id: MONDO:0013842
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Decreased activity of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 due to inactivating mutation(s) in the HSD11B1 gene. The condition is characterized by hyperandrogenism as a result of increased adrenocorticotropic hormone stimulation of the adrenal gland due to failure of cortisol-mediated down-regulation, and is clinically indistinguishable from H6PD deficiency.","definition_xrefs":["NCIT:C131084"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cortisone reductase deficiency","termid":"MONDO:0000193"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002525"],"is_obsolete":false,"name":"cortisone reductase deficiency 2","secondary_identifiers":["MEDGEN:766296","DOID:0090140","GARD:15830","OMIM:614662","UMLS:C3553382"],"synonyms":[{"name":"11-beta-hydroxysteroid dehydrogenase type 1 deficiency","type":"exact"},{"name":"CORTRD2","type":"exact"},{"name":"HSD11B1 cortisone reductase deficiency","type":"exact"},{"name":"cortisone reductase deficiency 2","type":"exact"},{"name":"cortisone reductase deficiency caused by mutation in HSD11B1","type":"exact"},{"name":"cortisone reductase deficiency type 2","type":"exact"}],"termid":"MONDO:0013842","xrefs":{"Monarch":{"xref_id":"0013842"}}}


id: PR:O14259
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sfp47 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O14259"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubp4-interactor sfp47 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC7D4.02c","synonyms":[{"name":"Spom972h-sfp47","type":"exact"}],"termid":"PR:O14259"}


id: GO:2000633
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of pre-microRNA processing.","definition_xrefs":["GOC:dph","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of miRNA processing","termid":"GO:1903800"},{"relation_name":"is_a","term_name":"regulation of pre-miRNA processing","termid":"GO:2000631"},{"relation_name":"positively_regulates","term_name":"pre-miRNA processing","termid":"GO:0031054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of pre-miRNA processing","synonyms":[{"name":"positive regulation of miRNA maturation","type":"exact"},{"name":"positive regulation of pre-microRNA processing","type":"exact"}],"termid":"GO:2000633"}


id: PBO:0084607
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Merged open reading frame; does not encode a discrete protein; YPR090W was originally annotated as an independent ORF, but as a result of a sequence change, it was merged with an adjacent ORF into a single reading frame, designated YPR089W","termid":"PBO:0084607"}


id: GO:0006064
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucuronate metabolic process","termid":"GO:0019585"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044248","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"glucuronate catabolic process","synonyms":[{"name":"glucuronate breakdown","type":"exact"},{"name":"glucuronate catabolism","type":"exact"},{"name":"glucuronate degradation","type":"exact"}],"termid":"GO:0006064"}


id: GO:0004258
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity.","definition_xrefs":["EC:3.4.16.5"],"gene_count":0,"genotype_count":0,"name":"obsolete vacuolar carboxypeptidase Y (obsolete GO:0004258)","synonyms":[{"name":"vacuolar carboxypeptidase Y","type":"exact"}],"termid":"GO:0004258"}


id: GO:0018185
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.","definition_xrefs":["RESID:AA0278"],"gene_count":0,"genotype_count":0,"name":"obsolete poly-N-methyl-propylamination (obsolete GO:0018185)","termid":"GO:0018185"}


id: PBO:0039025
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ArfGAP with GTPase domain, ankyrin repeat and PH domain 2","termid":"PBO:0039025"}


id: GO:0061428
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.","definition_xrefs":["PMID:17785431","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of transcription from RNA polymerase II promoter in response to hypoxia (obsolete GO:0061428)","termid":"GO:0061428"}


id: PBO:0002878
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"yippee-like protein","termid":"PBO:0002878"}


id: PR:Q9Y801
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug57 gene.","definition_xrefs":["UniProtKB:Q9Y801","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FAS1 domain-containing protein mug57 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC146.10","synonyms":[{"name":"Spom972h-mug57","type":"exact"},{"name":"meiotically up-regulated gene 57 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9Y801"}


id: FYPO:0004496
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a cell is smaller than normal and contains more than one septum, when the cell is in a culture in stationary phase.","definition_xrefs":["PomBase:mah","PMID:8292390"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small cell","termid":"FYPO:0000023"},{"relation_name":"is_a","term_name":"multiseptate cell","termid":"FYPO:0004295"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0000005"],"is_obsolete":false,"name":"small multiseptate cell during stationary phase","termid":"FYPO:0004496"}


id: PBO:0113266
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Phosphoinositide-binding regulator of ergosterol distribution; contains PX (Phox homology) domain; associated with ER-lipid droplet contact site; may facilitate ergosterol transport between plasma membrane and lipid droplets","termid":"PBO:0113266"}


id: GO:0007209
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by tachykinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:mah","GOC:signaling","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipase C-activating G protein-coupled receptor signaling pathway","termid":"GO:0007200"},{"relation_name":"is_a","term_name":"tachykinin receptor signaling pathway","termid":"GO:0007217"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"phospholipase C-activating tachykinin receptor signaling pathway","synonyms":[{"name":"activation of phospholipase C activity by tachykinin receptor signaling pathway","type":"related"},{"name":"activation of phospholipase C activity by tachykinin receptor signalling pathway","type":"related"},{"name":"tachykinin receptor, phospholipase C activating pathway","type":"related"}],"termid":"GO:0007209"}


id: GO:0003285
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the septum secundum over time, from its initial formation to the mature structure.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"atrial septum development","termid":"GO:0003283"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"septum secundum development","termid":"GO:0003285"}


id: GO:0015322
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.","definition_xrefs":["GOC:mtg_transport"],"gene_count":0,"genotype_count":0,"name":"obsolete secondary active oligopeptide transmembrane transporter activity (obsolete GO:0015322)","synonyms":[{"name":"oligopeptide porter activity","type":"related"}],"termid":"GO:0015322"}


id: GO:1901408
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of phosphorylation of RNA polymerase II C-terminal domain (obsolete GO:1901408)","synonyms":[{"name":"down regulation of CTD domain phosphorylation of RNA polymerase II","type":"exact"},{"name":"down regulation of generation of II(0) form of RNA polymerase II","type":"exact"},{"name":"down regulation of generation of hyperphosphorylated CTD of RNA polymerase II","type":"exact"},{"name":"down regulation of hyperphosphorylation of RNA polymerase II C-terminal domain","type":"exact"},{"name":"down regulation of phosphorylation of RNA polymerase II C-terminal domain","type":"exact"},{"name":"down-regulation of CTD domain phosphorylation of RNA polymerase II","type":"exact"},{"name":"down-regulation of generation of II(0) form of RNA polymerase II","type":"exact"},{"name":"down-regulation of generation of hyperphosphorylated CTD of RNA polymerase II","type":"exact"},{"name":"down-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain","type":"exact"},{"name":"down-regulation of phosphorylation of RNA polymerase II C-terminal domain","type":"exact"},{"name":"downregulation of CTD domain phosphorylation of RNA polymerase II","type":"exact"},{"name":"downregulation of generation of II(0) form of RNA polymerase II","type":"exact"},{"name":"downregulation of generation of hyperphosphorylated CTD of RNA polymerase II","type":"exact"},{"name":"downregulation of hyperphosphorylation of RNA polymerase II C-terminal domain","type":"exact"},{"name":"downregulation of phosphorylation of RNA polymerase II C-terminal domain","type":"exact"},{"name":"inhibition of CTD domain phosphorylation of RNA polymerase II","type":"exact"},{"name":"inhibition of generation of II(0) form of RNA polymerase II","type":"exact"},{"name":"inhibition of generation of hyperphosphorylated CTD of RNA polymerase II","type":"exact"},{"name":"inhibition of hyperphosphorylation of RNA polymerase II C-terminal domain","type":"exact"},{"name":"inhibition of phosphorylation of RNA polymerase II C-terminal domain","type":"narrow"},{"name":"negative regulation of CTD domain phosphorylation of RNA polymerase II","type":"exact"},{"name":"negative regulation of generation of II(0) form of RNA polymerase II","type":"exact"},{"name":"negative regulation of generation of hyperphosphorylated CTD of RNA polymerase II","type":"exact"},{"name":"negative regulation of hyperphosphorylation of RNA polymerase II C-terminal domain","type":"exact"}],"termid":"GO:1901408"}


id: PBO:0073840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 7 member 15, pseudogene","termid":"PBO:0073840"}


id: PBO:0028364
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-multiseptate_cell","termid":"PBO:0028364"}


id: GO:1902966
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.","definition_xrefs":["GOC:TermGenie","GOC:sjp","PMID:22621900","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein localization to early endosome","termid":"GO:1902965"},{"relation_name":"is_a","term_name":"positive regulation of protein localization to endosome","termid":"GO:1905668"},{"relation_name":"positively_regulates","term_name":"protein localization to early endosome","termid":"GO:1902946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein localization to early endosome","synonyms":[{"name":"activation of protein localisation in early endosome","type":"narrow"},{"name":"activation of protein localisation to early endosome","type":"narrow"},{"name":"activation of protein localization in early endosome","type":"narrow"},{"name":"activation of protein localization to early endosome","type":"narrow"},{"name":"positive regulation of protein localisation in early endosome","type":"exact"},{"name":"positive regulation of protein localisation to early endosome","type":"exact"},{"name":"positive regulation of protein localization in early endosome","type":"exact"},{"name":"up regulation of protein localisation in early endosome","type":"exact"},{"name":"up regulation of protein localisation to early endosome","type":"exact"},{"name":"up regulation of protein localization in early endosome","type":"exact"},{"name":"up regulation of protein localization to early endosome","type":"exact"},{"name":"up-regulation of protein localisation in early endosome","type":"exact"},{"name":"up-regulation of protein localisation to early endosome","type":"exact"},{"name":"up-regulation of protein localization in early endosome","type":"exact"},{"name":"up-regulation of protein localization to early endosome","type":"exact"},{"name":"upregulation of protein localisation in early endosome","type":"exact"},{"name":"upregulation of protein localisation to early endosome","type":"exact"},{"name":"upregulation of protein localization in early endosome","type":"exact"},{"name":"upregulation of protein localization to early endosome","type":"exact"}],"termid":"GO:1902966"}


id: GO:0045134
data:
  {"annotated_genes":["SJAG_01595","SJAG_03676"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70172,75991],"is_not":false,"summary":null,"term":"GO:0045134"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP + H2O = UMP + phosphate.","definition_xrefs":["RHEA:64876"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside diphosphate phosphatase activity","termid":"GO:0017110"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01595":null,"SJAG_03676":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"UDP phosphatase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:RXN-12197","KEGG_REACTION:R00155"],"synonyms":[{"name":"UDP phosphohydrolase activity","type":"exact"},{"name":"UDPase activity","type":"related"},{"name":"uridine 5'-diphosphatase activity","type":"related"},{"name":"uridine diphosphatase activity","type":"related"},{"name":"uridine-diphosphatase activity","type":"exact"}],"termid":"GO:0045134","terms_by_termid":{"GO:0045134":null}}


id: PBO:0001216
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA export receptor Nxt1","termid":"PBO:0001216"}


id: GO:1905520
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.","definition_xrefs":["GOC:rl","GOC:TermGenie","PMID:15797875","GOC:BHF","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of presynaptic active zone assembly","termid":"GO:1905518"},{"relation_name":"is_a","term_name":"positive regulation of presynapse assembly","termid":"GO:1905608"},{"relation_name":"positively_regulates","term_name":"presynaptic active zone assembly","termid":"GO:1904071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"positive regulation of presynaptic active zone assembly","synonyms":[{"name":"activation of pre-synaptic active zone assembly","type":"narrow"},{"name":"activation of pre-synaptic active zone component assembly","type":"narrow"},{"name":"activation of pre-synaptic active zone component formation","type":"narrow"},{"name":"activation of pre-synaptic active zone formation","type":"narrow"},{"name":"activation of presynaptic active zone assembly","type":"narrow"},{"name":"activation of presynaptic active zone formation","type":"narrow"},{"name":"positive regulation of pre-synaptic active zone assembly","type":"exact"},{"name":"positive regulation of pre-synaptic active zone component assembly","type":"narrow"},{"name":"positive regulation of pre-synaptic active zone component formation","type":"narrow"},{"name":"positive regulation of pre-synaptic active zone formation","type":"exact"},{"name":"positive regulation of presynaptic active zone formation","type":"exact"},{"name":"up regulation of pre-synaptic active zone assembly","type":"exact"},{"name":"up regulation of pre-synaptic active zone component assembly","type":"narrow"},{"name":"up regulation of pre-synaptic active zone component formation","type":"narrow"},{"name":"up regulation of pre-synaptic active zone formation","type":"exact"},{"name":"up regulation of presynaptic active zone assembly","type":"exact"},{"name":"up regulation of presynaptic active zone formation","type":"exact"},{"name":"up-regulation of pre-synaptic active zone assembly","type":"exact"},{"name":"up-regulation of pre-synaptic active zone component assembly","type":"narrow"},{"name":"up-regulation of pre-synaptic active zone component formation","type":"narrow"},{"name":"up-regulation of pre-synaptic active zone formation","type":"exact"},{"name":"up-regulation of presynaptic active zone assembly","type":"exact"},{"name":"up-regulation of presynaptic active zone formation","type":"exact"},{"name":"upregulation of pre-synaptic active zone assembly","type":"exact"},{"name":"upregulation of pre-synaptic active zone component assembly","type":"narrow"},{"name":"upregulation of pre-synaptic active zone component formation","type":"narrow"},{"name":"upregulation of pre-synaptic active zone formation","type":"exact"},{"name":"upregulation of presynaptic active zone assembly","type":"exact"},{"name":"upregulation of presynaptic active zone formation","type":"exact"}],"termid":"GO:1905520"}


id: GO:0150174
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process.","definition_xrefs":["PMID:30074985","GOC:aruk","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of phosphatidylcholine metabolic process","termid":"GO:0150172"},{"relation_name":"is_a","term_name":"negative regulation of phospholipid metabolic process","termid":"GO:1903726"},{"relation_name":"negatively_regulates","term_name":"phosphatidylcholine metabolic process","termid":"GO:0046470"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"negative regulation of phosphatidylcholine metabolic process","termid":"GO:0150174"}


id: PBO:0016048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EKC/KEOPS protein complex associated ATPase (predicted)","termid":"PBO:0016048"}


id: GO:0106436
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a quinone + glutathione + H+ + hydrogen sulfide = a quinol + S-sulfanylglutathione.","definition_xrefs":["RHEA:55156"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor","termid":"GO:0016672"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"glutathione-dependent sulfide quinone oxidoreductase activity","secondary_identifiers":["EC:1.8.5.8"],"synonyms":[{"name":"eukaryotic sulfide quinone oxidoreductase","type":"related"}],"termid":"GO:0106436"}


id: GO:0007338
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The union of male and female gametes to form a zygote.","definition_xrefs":["GOC:mtg_sensu","GOC:ems"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fertilization","termid":"GO:0009566"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"single fertilization","secondary_identifiers":["Reactome:R-HSA-1187000"],"synonyms":[{"name":"zygote biosynthesis","type":"related"},{"name":"zygote formation","type":"related"}],"termid":"GO:0007338"}


id: PBO:0049577
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H3.3 histone A","termid":"PBO:0049577"}


id: GO:0003128
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"specification of animal organ identity","termid":"GO:0010092"},{"relation_name":"part_of","term_name":"heart formation","termid":"GO:0060914"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"heart field specification","termid":"GO:0003128"}


id: PBO:0038706
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin gamma 1","termid":"PBO:0038706"}


id: PBO:0063069
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pannexin 2","termid":"PBO:0063069"}


id: PBO:0053584
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 607","termid":"PBO:0053584"}


id: GO:0075257
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of asexual sporulation resulting in formation of a cellular spore","termid":"GO:0043945"},{"relation_name":"is_a","term_name":"regulation of teliospore formation","termid":"GO:0075256"},{"relation_name":"positively_regulates","term_name":"teliospore formation","termid":"GO:0075255"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of teliospore formation","termid":"GO:0075257"}


id: PR:Q9UT76
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A translation initiation factor eIF-2B subunit beta that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR10233:SF9","PRO:DNx","OMA:SCHPO00681"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation initiation factor eIF-2B subunit beta (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC343.14c","secondary_identifiers":["UniProtKB:Q9UT76"],"synonyms":[{"name":"Spom972h-EIF2B2","type":"exact"},{"name":"eIF-2B GDP-GTP exchange factor subunit beta (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UT76"}


id: GO:0009988
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Cell recognition between cells. May involve the formation of specialized cell junctions.","definition_xrefs":["ISBN:0824072820"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell recognition","termid":"GO:0008037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell-cell recognition","termid":"GO:0009988"}


id: PBO:0048581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gamma-glutamyltransferase 5","termid":"PBO:0048581"}


id: PBO:0087508
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability","termid":"PBO:0087508"}


id: MONDO:0007691
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of Guillain-Barre syndrome (GBS) that occurs in persons or families with a genetic predisposition to the acute or chronic forms of GBS. Note that GBS is considered to be a complex multifactorial disorder with both genetic and environmental factors, and families with clear Mendelian inheritance have been rarely reported: a mutation in the PMP22 gene (601097) on chromosome 17 was identified in a single family with the acute (AIDP) and chronic (CIDP) forms of inflammatory demyelinating polyneuropathy.","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete chronic polyradiculoneuropathy (obsolete MONDO:0016170)","termid":"MONDO:0016170"},{"relation_name":"is_a","term_name":"Guillain-Barre syndrome","termid":"MONDO:0016218"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"Guillain-Barre syndrome, familial","secondary_identifiers":["GARD:18211","NANDO:1200030","NANDO:2100251","MEDGEN:901636","NANDO:2200905","OMIM:139393","UMLS:C4083008","SCTID:40956001","EFO:0009538","SCTID:716723000","MedDRA:10057645"],"synonyms":[{"name":"AIDP","type":"exact"},{"name":"GBS","type":"related"},{"name":"Guillain-Barre syndrome, familial","type":"exact"},{"name":"neuropathy, inflammatory demyelinating","type":"exact"},{"name":"polyneuropathy, inflammatory demyelinating, acute","type":"exact"}],"termid":"MONDO:0007691","xrefs":{"Monarch":{"xref_id":"0007691"}}}


id: PBO:0053027
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysosomal protein transmembrane 4 alpha","termid":"PBO:0053027"}


id: FYPO:0002618
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing valproic acid.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002058"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0002060","FYPO:0002058","FYPO:0000139","FYPO:0002057","FYPO:0000003"],"is_obsolete":false,"name":"normal growth on valproic acid","synonyms":[{"name":"normal cell population growth in presence of valproic acid","type":"exact"},{"name":"normal cell population growth on valproic acid","type":"exact"},{"name":"normal cellular response to valproic acid","type":"related"},{"name":"normal vegetative cell population growth on valproic acid","type":"exact"}],"termid":"FYPO:0002618"}


id: PBO:0052720
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 18 pseudogene 12","termid":"PBO:0052720"}


id: GO:0031098
data:
  {"annotated_genes":["SJAG_05000","SJAG_04551","SJAG_01787","SJAG_00610","SJAG_03969","SJAG_01114","SJAG_01181","SJAG_03753","SJAG_04825","SJAG_04522","SJAG_04666","SJAG_00424","SJAG_02392","SJAG_03263"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[101931,92021,110773],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000196"},{"annotations":[107411,95612,103589,99227,106845,118126],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:1903138"},{"annotations":[92176,89184,90522,102631,87830],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1903139"}]},"cv_name":"biological_process","definition":"The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to stress","termid":"GO:0033554"},{"relation_name":"is_a","term_name":"intracellular signal transduction","termid":"GO:0035556"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00424":null,"SJAG_00610":null,"SJAG_01114":null,"SJAG_01181":null,"SJAG_01787":null,"SJAG_02392":null,"SJAG_03263":null,"SJAG_03753":null,"SJAG_03969":null,"SJAG_04522":null,"SJAG_04551":null,"SJAG_04666":null,"SJAG_04825":null,"SJAG_05000":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"stress-activated protein kinase signaling cascade","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"JNK signaling pathway","type":"narrow"},{"name":"JNK signalling pathway","type":"narrow"},{"name":"SAPK signaling pathway","type":"exact"},{"name":"SAPK signalling pathway","type":"exact"},{"name":"stress-activated protein kinase signaling pathway","type":"exact"},{"name":"stress-activated protein kinase signalling pathway","type":"exact"}],"termid":"GO:0031098","terms_by_termid":{"GO:0000196":null,"GO:1903138":null,"GO:1903139":null}}


id: GO:0106336
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm.","definition_xrefs":["PMID:29180571"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"yolk syncytial layer development","synonyms":[{"name":"YSL development","type":"related"}],"termid":"GO:0106336"}


id: PBO:0038929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adhesion G protein-coupled receptor L3","termid":"PBO:0038929"}


id: PBO:0051561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interleukin 12A","termid":"PBO:0051561"}


id: MONDO:0017670
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autosomal dominant diffuse mutilating palmoplantar keratoderma (obsolete MONDO:0017670)","secondary_identifiers":["Orphanet:307773"],"synonyms":[{"name":"autosomal dominant diffuse mutilating palmoplantar hyperkeratosis","type":"exact"}],"termid":"MONDO:0017670","xrefs":{"Monarch":{"xref_id":"0017670"}}}


id: PBO:0048210
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gamma-aminobutyric acid type A receptor subunit gamma3","termid":"PBO:0048210"}


id: PBO:0077261
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane p24 trafficking protein 10 pseudogene 1","termid":"PBO:0077261"}


id: MONDO:0021296
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A in situ carcinoma that involves the renal pelvis.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney carcinoma in situ","termid":"MONDO:0004732"},{"relation_name":"is_a","term_name":"renal pelvis carcinoma","termid":"MONDO:0005519"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005240"],"is_obsolete":false,"name":"carcinoma in situ of renal pelvis","secondary_identifiers":["ICD9:233.9","MEDGEN:83855","NCIT:C4597","SCTID:92697000","UMLS:C0347184"],"synonyms":[{"name":"carcinoma in situ of kidney pelvis","type":"exact"},{"name":"carcinoma in situ of renal pelvis","type":"exact"},{"name":"carcinoma in situ of the kidney pelvis","type":"exact"},{"name":"carcinoma in situ of the renal pelvis","type":"exact"},{"name":"kidney pelvis carcinoma in situ","type":"exact"},{"name":"renal pelvis carcinoma in situ","type":"exact"},{"name":"renal pelvis in situ carcinoma","type":"exact"},{"name":"stage 0 renal pelvis carcinoma","type":"exact"},{"name":"stage 0is carcinoma of kidney pelvis","type":"exact"},{"name":"stage 0is carcinoma of renal pelvis","type":"exact"},{"name":"stage 0is carcinoma of the kidney pelvis","type":"exact"},{"name":"stage 0is carcinoma of the renal pelvis","type":"exact"},{"name":"stage 0is kidney pelvis carcinoma","type":"exact"},{"name":"stage 0is kidney renal pelvis urothelial cancer","type":"exact"},{"name":"stage 0is renal pelvis cancer","type":"exact"},{"name":"stage 0is renal pelvis cancer aJCC v7","type":"exact"},{"name":"stage 0is renal pelvis urothelial carcinoma","type":"exact"},{"name":"stage 0is renal pelvis urothelial carcinoma aJCC v7","type":"exact"}],"termid":"MONDO:0021296","xrefs":{"Monarch":{"xref_id":"0021296"}}}


id: PBO:0067587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 748, pseudogene","termid":"PBO:0067587"}


id: MONDO:0007000
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An disease caused by infection with Treponema.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial sexually transmitted disease","termid":"MONDO:0005323"},{"relation_name":"is_a","term_name":"gram-negative bacterial infections","termid":"MONDO:0021678"},{"relation_name":"is_a","term_name":"spirochaetales infections","termid":"MONDO:0021839"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Treponema infectious disease","secondary_identifiers":["NCIT:C85197","EFO:1001217","MESH:D014211"],"synonyms":[{"name":"Bejels","type":"narrow"},{"name":"Treponema caused disease or disorder","type":"exact"},{"name":"Treponema disease or disorder","type":"exact"},{"name":"Treponemal infection","type":"related"},{"name":"bejel","type":"narrow"},{"name":"infection, Treponemal","type":"related"},{"name":"infections, Treponemal","type":"related"}],"termid":"MONDO:0007000","xrefs":{"Monarch":{"xref_id":"0007000"}}}


id: PBO:0085565
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication","termid":"PBO:0085565"}


id: PR:O14013
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rrn5 gene.","definition_xrefs":["UniProtKB:O14013","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase I-specific transcription initiation factor rrn5 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC29A4.10","synonyms":[{"name":"Spom972h-rrn5","type":"exact"}],"termid":"PR:O14013"}


id: PBO:0025553
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA modification, acetylated cytidines","termid":"PBO:0025553"}


id: MONDO:0013980
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"punctate palmoplantar keratoderma type 1","termid":"MONDO:0019332"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"palmoplantar keratoderma, punctate type ib","secondary_identifiers":["OMIM:614936","GARD:15884","MEDGEN:767059","UMLS:C3554145"],"synonyms":[{"name":"PPKP1B","type":"exact"},{"name":"keratoderma, palmoplantar, punctate type IB","type":"exact"},{"name":"palmoplantar keratoderma, punctate type IB","type":"related"}],"termid":"MONDO:0013980","xrefs":{"Monarch":{"xref_id":"0013980"}}}


id: PBO:0040956
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCL2 interacting protein 3 pseudogene 27","termid":"PBO:0040956"}


id: MONDO:1010596
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hyperthyroidism that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hyperthyroidism, non-human animal","termid":"MONDO:1010055"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperthyroidism, horse","secondary_identifiers":["OMIA:000511-9796"],"termid":"MONDO:1010596","xrefs":{"Monarch":{"xref_id":"1010596"}}}


id: PBO:0028004
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_mitotic_chromosome_condensation","termid":"PBO:0028004"}


id: FYPO:0004695
data:
  {"alleles_by_uniquename":{"SJAG_00426:allele-1":{"allele_type":"amino_acid_mutation","description":"P363S","gene_uniquename":"SJAG_00426","name":"bbl1-P363S","uniquename":"SJAG_00426:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[119014],"is_not":false,"summary":null,"term":"FYPO:0004695"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more diglycerides measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of substance in cell during vegetative growth","termid":"FYPO:0001330"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00426":null},"genotype_count":1,"genotypes_by_uniquename":{"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"bbl1-P363S(aa)","display_uniquename":"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00426:allele-1","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased cellular diglyceride level","references_by_uniquename":{"PMID:25318672":null},"single_locus_annotated_genes":["SJAG_00426"],"single_locus_genotype_uniquenames":["bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type"],"synonyms":[{"name":"increased cellular DAG level","type":"exact"},{"name":"increased cellular diacylglycerol level","type":"exact"},{"name":"increased cellular diglyceride level during mitotic cell cycle","type":"related"},{"name":"increased cellular diglyceride level during vegetative growth","type":"exact"},{"name":"increased diglyceride accumulation","type":"related"}],"termid":"FYPO:0004695","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000006":null,"FYECO:0000162":null,"FYPO:0004695":null}}


id: GO:1901617
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of organic hydroxy compound.","definition_xrefs":["GOC:pr","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete organic hydroxy compound biosynthetic process (obsolete GO:1901617)","synonyms":[{"name":"organic hydroxy compound anabolism","type":"exact"},{"name":"organic hydroxy compound biosynthesis","type":"exact"},{"name":"organic hydroxy compound formation","type":"exact"},{"name":"organic hydroxy compound synthesis","type":"exact"}],"termid":"GO:1901617"}


id: PBO:0005001
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquinol-cytochrome-c reductase complex core protein Qcr2 (predicted)","termid":"PBO:0005001"}


id: MONDO:0019806
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Primary progressive aphasia (PPA) is a neurodegenerative disorder, characterized by a primary dissolution of language, with relative sparing of other mental faculties for at least the first 2 years of illness. PPA is recognized as the language variant in the frontotemporal dementia (FTD) spectrum of disorders. PPA can be classified into 3 subtypes based on specific speech and language features: semantic dementia (SD), progressive non-fluent aphasia (PNFA) and logopenic progressive aphasia (lv-PPA).","definition_xrefs":["Orphanet:95432"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurodegenerative disease","termid":"MONDO:0005559"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"primary progressive aphasia","secondary_identifiers":["NCIT:C85024","UMLS:C0282513","DOID:0081388","EFO:0009053","MEDGEN:79466","GARD:8541","MESH:D018888"],"synonyms":[{"name":"Mesulam syndrome","type":"exact"},{"name":"PPA","type":"exact"},{"name":"primary progressive aphasia syndrome","type":"related"}],"termid":"MONDO:0019806","xrefs":{"Monarch":{"xref_id":"0019806"}}}


id: GO:0099043
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat.","definition_xrefs":["GOC:vw","PMID:21779028","GOC:dos","GOC:lb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"clathrin-coated vesicle cargo loading","termid":"GO:0035652"},{"relation_name":"part_of","term_name":"clathrin-dependent endocytosis","termid":"GO:0072583"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0016192","GO:0006810"],"is_obsolete":false,"name":"cargo loading involved in clathrin-dependent endocytosis","termid":"GO:0099043"}


id: GO:0160112
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A structural network of microtubule inner proteins (MIPs) located inside the lumen of the B tubule of the axonemal microtubule doublet that helps stabilize the B tubule.","definition_xrefs":["GOC:krc","PMID:37295417","PMID:29430673"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"A axonemal microtubule","termid":"GO:0097649"},{"relation_name":"part_of","term_name":"axonemal microtubule doublet inner sheath","termid":"GO:0160110"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0015630"],"is_obsolete":false,"name":"axonemal B tubule inner sheath","termid":"GO:0160112"}


id: PBO:0001439
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"expression induced by hydrogen peroxide","termid":"PBO:0001439"}


id: PBO:0081024
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger CCCH-type containing 6","termid":"PBO:0081024"}


id: GO:0047907
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.","definition_xrefs":["EC:5.2.1.6","RHEA:21848"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cis-trans isomerase activity","termid":"GO:0016859"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016853","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"furylfuramide isomerase activity","secondary_identifiers":["KEGG_REACTION:R04538","MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN"],"synonyms":[{"name":"2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity","type":"related"}],"termid":"GO:0047907"}


id: PBO:0078976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ser (anticodon GCT) 4-1","termid":"PBO:0078976"}


id: SO:0001934
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A repeat_region containing repeat_units of 1 bp that is repeated multiple times in tandem.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tandem_repeat","termid":"SO:0000705"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monomeric_repeat","synonyms":[{"name":"monomeric repeat","type":"exact"}],"termid":"SO:0001934"}


id: FYPO:0004765
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cell population growth","termid":"FYPO:0000047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000003","FYPO:0002058","FYPO:0000139","FYPO:0002057"],"is_obsolete":false,"name":"normal cell population growth during glucose starvation","synonyms":[{"name":"normal cell population growth during glucose depletion","type":"exact"},{"name":"normal cell population growth during glucose deprivation","type":"exact"},{"name":"normal cell population growth during glucose limitation","type":"related"},{"name":"normal growth during glucose starvation","type":"broad"}],"termid":"FYPO:0004765"}


id: GO:0150051
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The network of the Golgi apparatus structures located within the postsynapse.","definition_xrefs":["GOC:aruk","GOC:bc","PMID:23838184"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Golgi apparatus","termid":"GO:0005794"},{"relation_name":"part_of","term_name":"postsynapse","termid":"GO:0098794"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005794"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0005794","GO:0005575"],"is_obsolete":false,"name":"postsynaptic Golgi apparatus","synonyms":[{"name":"Golgi outpost","type":"related"}],"termid":"GO:0150051"}


id: PBO:0001411
data:
  {"annotation_feature_type":"gene","cv_name":"sequence_feature","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein NES","termid":"PBO:0001411"}


id: GO:0047149
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H+.","definition_xrefs":["EC:2.1.1.3","RHEA:22788"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-methyltransferase activity","termid":"GO:0008172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0003674","GO:0016741"],"is_obsolete":false,"name":"thetin-homocysteine S-methyltransferase activity","secondary_identifiers":["KEGG_REACTION:R04153","MetaCyc:2.1.1.3-RXN"],"synonyms":[{"name":"dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity","type":"related"},{"name":"dimethylthetin-homocysteine methyltransferase activity","type":"related"},{"name":"thetin-homocysteine methylpherase activity","type":"related"}],"termid":"GO:0047149"}


id: PBO:0061070
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NKD inhibitor of WNT signaling pathway 1","termid":"PBO:0061070"}


id: MONDO:0015222
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A respiratory or mediastinal malformation that is part of a larger syndrome.","definition_xrefs":["MONDO:patterns/syndromic"],"gene_count":0,"genotype_count":0,"name":"obsolete syndromic respiratory or mediastinal malformation (obsolete MONDO:0015222)","secondary_identifiers":["Orphanet:108995"],"synonyms":[{"name":"syndrome associated with respiratory or mediastinal malformation","type":"exact"},{"name":"syndromic respiratory or mediastinal malformation","type":"exact"}],"termid":"MONDO:0015222","xrefs":{"Monarch":{"xref_id":"0015222"}}}


id: PBO:0011960
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase allele types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wild_type","termid":"PBO:0011960"}


id: GO:0000205
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).","definition_xrefs":["PMID:9561267"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of MAPK during sporulation (sensu Saccharomyces) (obsolete GO:0000205)","synonyms":[{"name":"activation of MAPK during sporulation (sensu Saccharomyces)","type":"exact"}],"termid":"GO:0000205"}


id: MONDO:0018208
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"neurofibromatosis type 1","termid":"MONDO:0018975"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"neurofibromatosis type 1 due to NF1 mutation or intragenic deletion","secondary_identifiers":["Orphanet:363700","GARD:17570","UMLS:C5779636","MEDGEN:1842855"],"synonyms":[{"name":"Von Recklinghausen disease due to NF1 mutation or intragenic deletion","type":"exact"}],"termid":"MONDO:0018208","xrefs":{"Monarch":{"xref_id":"0018208"}}}


id: GO:0032237
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that initiates the activity of an inactive store-operated calcium channel.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of store-operated calcium channel activity","termid":"GO:1901341"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"activation of store-operated calcium channel activity","termid":"GO:0032237"}


id: GO:0035827
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other.","definition_xrefs":["GOC:yaf"],"gene_count":0,"genotype_count":0,"name":"obsolete rubidium ion transmembrane transporter activity (obsolete GO:0035827)","synonyms":[{"name":"Rb+ transmembrane transporter activity","type":"exact"},{"name":"rubidium cation transmembrane transporter activity","type":"exact"},{"name":"rubidium transmembrane transporter activity","type":"related"}],"termid":"GO:0035827"}


id: MONDO:0002231
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete malignant ovarian germ cell neoplasm (obsolete MONDO:0002231)","termid":"MONDO:0002231","xrefs":{"Monarch":{"xref_id":"0002231"}}}


id: FYPO:0004925
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the outer surface of the ascospore wall is rougher and less regular than normal.","definition_xrefs":["PMID:20410137","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal ascospore wall morphology","termid":"FYPO:0003138"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002946"},{"rel_name":"output_of","termid":"FYPO:0000121"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0002946","FYPO:0000121","FYPO:0000631","FYPO:0005447"],"is_obsolete":false,"name":"irregular ascospore wall","synonyms":[{"name":"irregular ascospore wall surface texture","type":"exact"},{"name":"irregular spore wall","type":"exact"},{"name":"rough ascospore wall","type":"exact"}],"termid":"FYPO:0004925"}


id: PBO:0058598
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6730","termid":"PBO:0058598"}


id: PBO:0049140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamic--pyruvic transaminase","termid":"PBO:0049140"}


id: GO:1904421
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.","definition_xrefs":["PMID:12057922","GO_REF:0000071","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to D-galactosamine","termid":"GO:1904421"}


id: PBO:0065593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prothymosin alpha pseudogene 9","termid":"PBO:0065593"}


id: FYPO:0007651
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to pericentric heterochromatin is abolished during mitosis.","definition_xrefs":["PMID:14730319","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular component organization","termid":"FYPO:0000335"},{"relation_name":"is_a","term_name":"abnormal mitotic cell cycle process","termid":"FYPO:0002737"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"},{"relation_name":"is_a","term_name":"abnormal protein localization to pericentric heterochromatin","termid":"FYPO:0007648"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000138","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to pericentric heterochromatin during mitosis","synonyms":[{"name":"abolished protein localization to centromeric heterochromatin during mitosis","type":"exact"},{"name":"abolished protein localization to nuclear centromeric heterochromatin during mitosis","type":"exact"},{"name":"abolished protein localization to pericentric heterochromatin during mitosis during vegetative growth","type":"exact"},{"name":"abolished protein localization to pericentric heterochromatin during mitotic M phase","type":"related"},{"name":"abolished protein localization to pericentric heterochromatin during mitotic nuclear division","type":"exact"}],"termid":"FYPO:0007651"}


id: GO:1990160
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.","definition_xrefs":["PMID:8663105","PMID:19941825","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pre-primosome complex","termid":"GO:1990099"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005694"}],"interesting_parent_ids":["GO:0005694","GO:0005575","GO:0032991"],"is_obsolete":false,"name":"DnaB-DnaC-Rep-PriC complex","synonyms":[{"name":"DnaB-DnaC-Rep-PriC preprimosome","type":"exact"},{"name":"phi-X174-type preprimosome","type":"related"}],"termid":"GO:1990160"}


id: PBO:0114382
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane carboxylic acid transmembrane transporter Tna1","termid":"PBO:0114382"}


id: PBO:0069690
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 969, pseudogene","termid":"PBO:0069690"}


id: PBO:0028567
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_meiotic_homologous_chromosome_biorientation","termid":"PBO:0028567"}


id: PBO:0042412
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell division cycle 25B","termid":"PBO:0042412"}


id: PBO:0026926
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_serine_phosphorylation_at_RxxS_site","termid":"PBO:0026926"}


id: PBO:0026780
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_RNA_level_during_cellular_response_to_salt_stress","termid":"PBO:0026780"}


id: PBO:0066793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 92","termid":"PBO:0066793"}


id: PBO:0046109
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 4E family member 2","termid":"PBO:0046109"}


id: PBO:0081813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 736 pseudogene 6, Y-linked","termid":"PBO:0081813"}


id: PBO:0028283
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_chromatin_silencing_at_silent_mating-type_cassette","termid":"PBO:0028283"}


id: MONDO:0014540
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any amelogenesis imperfecta in which the cause of the disease is a mutation in the ITGB6 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amelogenesis imperfecta type 1","termid":"MONDO:0015047"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amelogenesis imperfecta type 1H","secondary_identifiers":["UMLS:C4015557","MEDGEN:863994","OMIM:616221","DOID:0110064","GARD:16071"],"synonyms":[{"name":"AI1H","type":"exact"},{"name":"ITGB6 amelogenesis imperfecta","type":"exact"},{"name":"amelogenesis imperfecta caused by mutation in ITGB6","type":"exact"},{"name":"amelogenesis imperfecta type IH","type":"exact"},{"name":"amelogenesis imperfecta, type 1H","type":"related"},{"name":"amelogenesis imperfecta, type IH","type":"related"}],"termid":"MONDO:0014540","xrefs":{"Monarch":{"xref_id":"0014540"}}}


id: PBO:0081501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 402, pseudogene","termid":"PBO:0081501"}


id: FYPO:0002050
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which vegetative a cell is branched, elongated, has no septum, and contains more than one nucleus.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branched, elongated cell","termid":"FYPO:0001512"},{"relation_name":"is_a","term_name":"elongated multinucleate aseptate vegetative cell","termid":"FYPO:0002049"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000631","FYPO:0000005","FYPO:0005447","FYPO:0000032","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"branched elongated multinucleate aseptate vegetative cell","synonyms":[{"name":"branched elongated multinucleate aseptate cell during vegetative growth","type":"exact"},{"name":"branched elongated multinucleate aseptate vegetative cell during mitotic cell cycle","type":"related"}],"termid":"FYPO:0002050"}


id: GO:0052033
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response (obsolete GO:0052033)","synonyms":[{"name":"MAMP dependent activation of host innate immunity","type":"exact"},{"name":"MAMP dependent induction of host innate immunity","type":"exact"},{"name":"PAMP dependent activation of host innate immunity","type":"exact"},{"name":"PAMP dependent induction of host innate immunity","type":"exact"},{"name":"PTI","type":"related"},{"name":"general elicitor-dependent activation of host innate immunity","type":"exact"},{"name":"general elicitor-dependent induction of host innate immunity","type":"exact"},{"name":"pathogen-associated molecular pattern dependent activation by organism of host innate immunity","type":"exact"},{"name":"pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity","type":"exact"},{"name":"pattern-triggered immunity","type":"related"}],"termid":"GO:0052033"}


id: GO:1905278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of epithelial tube formation.","definition_xrefs":["GOC:bhm","GOC:TermGenie","PMID:25745997","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"is_a","term_name":"regulation of epithelial tube formation","termid":"GO:1905276"},{"relation_name":"is_a","term_name":"positive regulation of morphogenesis of an epithelium","termid":"GO:1905332"},{"relation_name":"positively_regulates","term_name":"epithelial tube formation","termid":"GO:0072175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of epithelial tube formation","synonyms":[{"name":"activation of epithelial tube formation","type":"narrow"},{"name":"up regulation of epithelial tube formation","type":"exact"},{"name":"up-regulation of epithelial tube formation","type":"exact"},{"name":"upregulation of epithelial tube formation","type":"exact"}],"termid":"GO:1905278"}


id: PBO:0049370
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"general transcription factor IIIA","termid":"PBO:0049370"}


id: GO:0010620
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.","definition_xrefs":["GOC:bf","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteasome-mediated ubiquitin-dependent protein catabolic process","termid":"GO:0043161"},{"relation_name":"is_a","term_name":"negative regulation of DNA-templated transcription","termid":"GO:0045892"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"part_of","termid":"GO:0030163"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006351"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0030163"}],"interesting_parent_ids":["GO:0030163","GO:0006351","GO:0010467","GO:0006355","GO:0008150"],"is_obsolete":false,"name":"negative regulation of transcription by transcription factor catabolism","termid":"GO:0010620"}


id: MONDO:1012360
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"neuronal vacuolar disorder, non-human animal","termid":"MONDO:1011873"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neuronal vacuolar disorder, dog","secondary_identifiers":["OMIA:001303-9615"],"termid":"MONDO:1012360","xrefs":{"Monarch":{"xref_id":"1012360"}}}


id: PBO:0082384
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle","termid":"PBO:0082384"}


id: GO:0034017
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].","definition_xrefs":["RHEA:23568"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, transposing C=C bonds","termid":"GO:0016863"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016853"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016853"],"is_obsolete":false,"name":"trans-2-decenoyl-acyl-carrier-protein isomerase activity","secondary_identifiers":["GO:0043832","EC:5.3.3.14","MetaCyc:5.3.3.14-RXN"],"synonyms":[{"name":"beta-hydroxydecanoyl thioester dehydrase activity","type":"broad"},{"name":"decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity","type":"related"},{"name":"trans-2, cis-3 decenoyl-ACP isomerase activity","type":"exact"},{"name":"trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity","type":"exact"},{"name":"trans-2,cis-3-decenoyl-ACP isomerase activity","type":"related"},{"name":"trans-2-cis-3-decenoyl-ACP isomerase activity","type":"related"},{"name":"trans-2-decenoyl-ACP isomerase activity","type":"related"}],"termid":"GO:0034017"}


id: GO:0008940
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor.","definition_xrefs":["RHEA:21068"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on other nitrogenous compounds as donors","termid":"GO:0016661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"nitrate reductase activity","synonyms":[{"name":"nitrate reductase (acceptor)","type":"related"},{"name":"nitrite:(acceptor) oxidoreductase","type":"related"},{"name":"nitrite:acceptor oxidoreductase","type":"related"},{"name":"respiratory nitrate reductase activity","type":"narrow"}],"termid":"GO:0008940"}


id: GO:0005919
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A septate junction in which regular arrays of electron-dense septae span the intermembrane space.","definition_xrefs":["PMID:11700298"],"direct_ancestors":[{"relation_name":"is_a","term_name":"septate junction","termid":"GO:0005918"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"pleated septate junction","synonyms":[{"name":"pleated desmosome","type":"related"}],"termid":"GO:0005919"}


id: PBO:0032730
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-1,2-mannosyltransferase Smp3 (predicted)","termid":"PBO:0032730"}


id: GO:0010928
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"regulates","term_name":"auxin-activated signaling pathway","termid":"GO:0009734"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of auxin mediated signaling pathway","synonyms":[{"name":"regulation of auxin mediated signalling pathway","type":"exact"}],"termid":"GO:0010928"}


id: PR:O94345
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mrpl8 gene.","definition_xrefs":["UniProtKB:O94345","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"54S ribosomal protein L8, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1271.13","synonyms":[{"name":"Spom972h-mrpl8","type":"exact"}],"termid":"PR:O94345"}


id: GO:1904501
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin-mediated maintenance of transcription.","definition_xrefs":["GO_REF:0000058","PMID:22723415","GOC:nc","GOC:BHF","GOC:TermGenie","GOC:BHF_telomere"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of chromatin-mediated maintenance of transcription (obsolete GO:1904501)","synonyms":[{"name":"activation of chromatin-mediated maintenance of transcription","type":"narrow"},{"name":"up regulation of chromatin-mediated maintenance of transcription","type":"exact"},{"name":"up-regulation of chromatin-mediated maintenance of transcription","type":"exact"},{"name":"upregulation of chromatin-mediated maintenance of transcription","type":"exact"}],"termid":"GO:1904501"}


id: PBO:0042214
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin L2","termid":"PBO:0042214"}


id: GO:0102691
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine = H+ + benzyladenine-7-N-glucoside + UDP.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete UDP-glucose:benzyladenine 7-N-glucosyltransferase activity (obsolete GO:0102691)","termid":"GO:0102691"}


id: PBO:0069066
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 313, pseudogene","termid":"PBO:0069066"}


id: PBO:0089980
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAJ protein Xdj1","termid":"PBO:0089980"}


id: PBO:0062959
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"poly(A) binding protein cytoplasmic 1 pseudogene 2","termid":"PBO:0062959"}


id: GO:2000793
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any cell proliferation that is involved in heart valve development.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population proliferation","termid":"GO:0008283"},{"relation_name":"part_of","term_name":"heart valve development","termid":"GO:0003170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell proliferation involved in heart valve development","synonyms":[{"name":"cell proliferation of cardiac valve development","type":"exact"},{"name":"cell proliferation of heart valve development","type":"exact"}],"termid":"GO:2000793"}


id: MONDO:0010627
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"X-linked lymphoproliferative disease is a hereditary immunodeficiency characterized, in the majority of cases, by an inadequate immune response to infection with the Epstein-Barr virus (EBV).","definition_xrefs":["Orphanet:2442"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary hemophagocytic lymphohistiocytosis","termid":"MONDO:0015541"},{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"},{"relation_name":"is_a","term_name":"lymphoproliferative syndrome","termid":"MONDO:0016537"},{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"X-linked lymphoproliferative syndrome","secondary_identifiers":["NANDO:2200725","MedDRA:10068348","SCTID:77121009","GARD:10915","MEDGEN:107498","UMLS:C0549463","DOID:0060705","NANDO:1200351","NORD:1865","NCIT:C61246","ICD9:238.79"],"synonyms":[{"name":"Duncan disease","type":"exact"},{"name":"Purtilo syndrome","type":"exact"},{"name":"SH2D1A-related lymphoproliferative disease, X-linked","type":"related"},{"name":"X linked Lymphoproliferative Syndrome","type":"exact"},{"name":"X-linked lymphoproliferative disease","type":"related"},{"name":"X-linked lymphoproliferative syndrome","type":"exact"},{"name":"X-linked lymphoproliferative syndrome 1","type":"related"},{"name":"X-linked lymphoproliferative syndrome type 1","type":"narrow"},{"name":"XLP","type":"related"},{"name":"XLP1","type":"narrow"},{"name":"lymphoproliferative syndrome X-linked 1","type":"related"},{"name":"lymphoproliferative syndrome, X-linked","type":"exact"},{"name":"lymphoproliferative syndrome, X-linked, 1","type":"related"},{"name":"lymphoproliferative syndrome, X-linked, type 1","type":"narrow"}],"termid":"MONDO:0010627","xrefs":{"Monarch":{"xref_id":"0010627"}}}


id: MOD:01758
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Proteome Sciences TMT6plex-130 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent O-acylated residue","termid":"MOD:01719"},{"relation_name":"is_a","term_name":"TMT6plex-130 reporter+balance reagent acylated residue","termid":"MOD:01752"},{"relation_name":"is_a","term_name":"O3-acylated L-threonine","termid":"MOD:02004"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-130 reporter+balance reagent O3-acylated threonine","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01758"}


id: PBO:0039101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosylhomocysteinase pseudogene 5","termid":"PBO:0039101"}


id: MONDO:0008034
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Becker muscular dystrophy","termid":"MONDO:0010311"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"muscular dystrophy, pseudohypertrophic, with Internalized capillaries","secondary_identifiers":["UMLS:C1834652","MESH:C563554","GARD:15089","OMIM:159050","MEDGEN:320399"],"synonyms":[{"name":"muscular dystrophy, pseudohypertrophic, with Internalized capillaries","type":"exact"}],"termid":"MONDO:0008034","xrefs":{"Monarch":{"xref_id":"0008034"}}}


id: PBO:0047245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 237 member A","termid":"PBO:0047245"}


id: GO:0004626
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.","definition_xrefs":["EC:3.1.1.4"],"gene_count":0,"genotype_count":0,"name":"obsolete cytosolic phospholipase A2 activity (obsolete GO:0004626)","synonyms":[{"name":"cytosolic phospholipase A2 activity","type":"exact"}],"termid":"GO:0004626"}


id: PBO:0057584
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 889","termid":"PBO:0057584"}


id: MONDO:0000348
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete posterior polar cataract (obsolete MONDO:0000348)","secondary_identifiers":["DOID:0050537"],"synonyms":[{"name":"cataract, posterior polar","type":"exact"},{"name":"obsolete posterior polar cataract (disease)","type":"exact"}],"termid":"MONDO:0000348","xrefs":{"Monarch":{"xref_id":"0000348"}}}


id: MONDO:0011923
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any osteoarthritis in which the cause of the disease is a mutation in the ASPN gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteoarthritis susceptibility 3","secondary_identifiers":["MEDGEN:382650","OMIM:607850","UMLS:C2675609"],"synonyms":[{"name":"ASPN osteoarthritis","type":"exact"},{"name":"OS3","type":"related"},{"name":"osteoarthritis caused by mutation in ASPN","type":"exact"},{"name":"osteoarthritis of knee/hip","type":"related"},{"name":"osteoarthritis susceptibility 3","type":"exact"},{"name":"osteoarthritis susceptibility type 3","type":"exact"}],"termid":"MONDO:0011923","xrefs":{"Monarch":{"xref_id":"0011923"}}}


id: PBO:0050172
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 3 pseudogene 28","termid":"PBO:0050172"}


id: PBO:0003720
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase I, II and III subunit Rpc10","termid":"PBO:0003720"}


id: PBO:0060549
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAXD antisense RNA 1","termid":"PBO:0060549"}


id: SO:0001608
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant of a codon causing the substitution of a non conservative amino acid for another in the resulting polypeptide.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino_acid_substitution","termid":"SO:0001606"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non_conservative_amino_acid_substitution","synonyms":[{"name":"non conservative amino acid substitution","type":"exact"}],"termid":"SO:0001608"}


id: PBO:0030547
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_valine_import","termid":"PBO:0030547"}


id: PBO:0076558
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TBC1 domain family member 2","termid":"PBO:0076558"}


id: PBO:0078462
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thyrotropin releasing hormone","termid":"PBO:0078462"}


id: MONDO:0003027
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A usually aggressive malignant vascular tumor primarily involving the thyroid gland. It is often associated with longstanding nodular goiter.","definition_xrefs":["NCIT:C6043"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thyroid sarcoma","termid":"MONDO:0003028"},{"relation_name":"is_a","term_name":"angiosarcoma","termid":"MONDO:0016982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"thyroid gland angiosarcoma","secondary_identifiers":["DOID:4514","MEDGEN:277819","UMLS:C1336748"],"synonyms":[{"name":"angiosarcoma (disease) of thyroid gland","type":"exact"},{"name":"angiosarcoma of the thyroid","type":"exact"},{"name":"angiosarcoma of the thyroid gland","type":"exact"},{"name":"angiosarcoma of thyroid","type":"exact"},{"name":"angiosarcoma of thyroid gland","type":"exact"},{"name":"hemangiosarcoma of the thyroid","type":"exact"},{"name":"hemangiosarcoma of the thyroid gland","type":"exact"},{"name":"hemangiosarcoma of thyroid","type":"exact"},{"name":"hemangiosarcoma of thyroid gland","type":"exact"},{"name":"thyroid angiosarcoma","type":"exact"},{"name":"thyroid gland angiosarcoma","type":"exact"},{"name":"thyroid gland angiosarcoma (disease)","type":"exact"},{"name":"thyroid gland hemangiosarcoma","type":"exact"},{"name":"thyroid gland malignant hemangioendothelioma","type":"exact"},{"name":"thyroid hemangiosarcoma","type":"exact"}],"termid":"MONDO:0003027","xrefs":{"Monarch":{"xref_id":"0003027"}}}


id: FYPO:0003224
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone acetylation during vegetative growth","termid":"FYPO:0003221"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001312","FYPO:0001320","FYPO:0000257"],"is_obsolete":false,"name":"normal histone H3-K14 acetylation during vegetative growth","synonyms":[{"name":"normal histone H3 K14 acetylation during vegetative growth","type":"exact"},{"name":"normal histone H3-K14 acetylation during mitotic cell cycle","type":"related"},{"name":"normal histone H3K14 acetylation during vegetative growth","type":"exact"},{"name":"normal histone lysine H3 K14 acetylation during vegetative growth","type":"exact"}],"termid":"FYPO:0003224"}


id: FYPO:0001151
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition when the cell is subject to starvation for one or more nutrients.","definition_xrefs":["PMID:19366728","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell cycle arrest at mitotic G2/M phase transition","termid":"FYPO:0000400"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000631","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"cell cycle arrest at mitotic G2/M phase transition during starvation","synonyms":[{"name":"cell cycle arrest at mitotic G2/M phase transition during depletion","type":"exact"},{"name":"cell cycle arrest at mitotic G2/M phase transition during deprivation","type":"exact"},{"name":"cell cycle arrest in mitotic G2 phase during starvation","type":"related"},{"name":"mitotic G2 phase arrest during starvation","type":"exact"},{"name":"mitotic cell cycle arrest at mitotic G2/M phase transition during starvation","type":"exact"}],"termid":"FYPO:0001151"}


id: GO:0036401
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.","definition_xrefs":["PMID:12951076","GOC:ha","PMID:19186060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuropeptide receptor activity","termid":"GO:0008188"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"pyrokinin receptor activity","synonyms":[{"name":"PK receptor activity","type":"exact"}],"termid":"GO:0036401"}


id: PBO:0045571
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dual specificity phosphatase 21","termid":"PBO:0045571"}


id: GO:0001188
data:
  {"annotated_genes":["SJAG_03956","SJAG_00692","SJAG_02813"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[63593,67956,77115],"is_not":false,"summary":null,"term":"GO:0001188"}]},"cv_name":"biological_process","definition":"The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides.","definition_xrefs":["GOC:txnOH","PMID:14969726"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription preinitiation complex assembly","termid":"GO:0070897"},{"relation_name":"part_of","term_name":"transcription initiation at RNA polymerase I promoter","termid":"GO:0006361"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00692":null,"SJAG_02813":null,"SJAG_03956":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006351"}],"interesting_parent_ids":["GO:0006351","GO:0010467","GO:0065003","GO:0008150","GO:0044085"],"is_obsolete":false,"name":"RNA polymerase I preinitiation complex assembly","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000108":null},"secondary_identifiers":["GO:0001189"],"synonyms":[{"name":"RNA polymerase I transcriptional preinitiation complex assembly","type":"exact"},{"name":"RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript","type":"narrow"},{"name":"RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript","type":"narrow"}],"termid":"GO:0001188","terms_by_termid":{"GO:0001188":null}}


id: MONDO:0001902
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of agammaglobulinemia that is present from birth.","definition_xrefs":["MONDO:patterns/congenital"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"B cell deficiency","termid":"MONDO:0002211"},{"relation_name":"is_a","term_name":"congenital hematological disorder","termid":"MONDO:0009332"},{"relation_name":"is_a","term_name":"agammaglobulinemia","termid":"MONDO:0015977"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"congenital agammaglobulinemia","secondary_identifiers":["UMLS:C5574711","ICD9:279.04","MEDGEN:1806025","DOID:14177"],"synonyms":[{"name":"congenital agammaglobulinemia","type":"exact"},{"name":"congenital hypogammaglobulinaemia","type":"exact"},{"name":"congenital hypogammaglobulinemia (finding)","type":"exact"}],"termid":"MONDO:0001902","xrefs":{"Monarch":{"xref_id":"0001902"}}}


id: PBO:0057640
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1231","termid":"PBO:0057640"}


id: PBO:0072833
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SAP18 pseudogene 3","termid":"PBO:0072833"}


id: GO:0034046
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a sequence of guanine residues in an RNA molecule.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"poly-purine tract binding","termid":"GO:0070717"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003723","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"poly(G) binding","synonyms":[{"name":"poly(G) binding, within an RNA molecule","type":"exact"},{"name":"poly(rG) binding","type":"exact"}],"termid":"GO:0034046"}


id: GO:0001173
data:
  {"annotated_genes":["SJAG_01523"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76975],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001174"}]},"cv_name":"biological_process","definition":"Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.","definition_xrefs":["PMID:18846104","GOC:txnOH","PMID:16826228"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA biosynthetic process","termid":"GO:0032774"},{"relation_name":"part_of","term_name":"DNA-templated transcription initiation","termid":"GO:0006352"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01523":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006351"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006351","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"DNA-templated transcriptional start site selection","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["GO:0001176"],"synonyms":[{"name":"DNA-dependent transcriptional start site selection","type":"exact"},{"name":"transcriptional start site selection at bacterial-type RNA polymerase promoter","type":"narrow"}],"termid":"GO:0001173","terms_by_termid":{"GO:0001174":null}}


id: PBO:0072495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein SA pseudogene 24","termid":"PBO:0072495"}


id: GO:0033895
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.","definition_xrefs":["EC:3.1.26.9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA endonuclease activity, producing 5'-phosphomonoesters","termid":"GO:0016891"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0140098"}],"interesting_parent_ids":["GO:0140098","GO:0003824","GO:0003674","GO:0016787","GO:0016788"],"is_obsolete":false,"name":"ribonuclease [poly-(U)-specific] activity","synonyms":[{"name":"ribonuclease (uracil-specific) activity","type":"related"},{"name":"uracil-specific RNase activity","type":"related"},{"name":"uracil-specific endoribonuclease activity","type":"related"}],"termid":"GO:0033895"}


id: MONDO:0016660
data:
  {"annotated_genes":["SJAG_01293","SJAG_02737","SJAG_04259","SJAG_04699","SJAG_04070","SJAG_03161","SJAG_00768","SJAG_03617","SJAG_03891","SJAG_01082","SJAG_00773"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84834],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054716"},{"annotations":[85747],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054761"},{"annotations":[85771],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054804"},{"annotations":[85772],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054806"},{"annotations":[86141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032583"},{"annotations":[86109],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030339"},{"annotations":[85500],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0031060"},{"annotations":[85459],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011488"},{"annotations":[85362,85363],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0859342"},{"annotations":[85013],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011437"}]},"cv_name":"mondo","definition":"Autosomal recessive primary microcephaly (MCPH) is a rare genetically heterogeneous disorder of neurogenic brain development characterized by reduced head circumference at birth with no gross anomalies of brain architecture and variable degrees of intellectual impairment.","definition_xrefs":["Orphanet:2512"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete neuro-ophthalmological disease (obsolete MONDO:0015368)","termid":"MONDO:0015368"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"isolated congenital microcephaly","termid":"MONDO:0016056"},{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00768":null,"SJAG_00773":null,"SJAG_01082":null,"SJAG_01293":null,"SJAG_02737":null,"SJAG_03161":null,"SJAG_03617":null,"SJAG_03891":null,"SJAG_04070":null,"SJAG_04259":null,"SJAG_04699":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive primary microcephaly","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:715981004","UMLS:C3711387","DOID:0070296","MESH:C579935","OMIMPS:251200","MEDGEN:777995","GARD:12117"],"synonyms":[{"name":"MCPH","type":"exact"},{"name":"microcephalia vera","type":"exact"},{"name":"microcephaly vera","type":"exact"},{"name":"microcephaly, primary autosomal recessive","type":"exact"},{"name":"microcephaly, primary, autosomal recessive","type":"exact"},{"name":"true microcephaly","type":"broad"}],"termid":"MONDO:0016660","terms_by_termid":{"MONDO:0011437":null,"MONDO:0011488":null,"MONDO:0030339":null,"MONDO:0031060":null,"MONDO:0032583":null,"MONDO:0054716":null,"MONDO:0054761":null,"MONDO:0054804":null,"MONDO:0054806":null,"MONDO:0859342":null},"xrefs":{"Monarch":{"xref_id":"0016660"}}}


id: PBO:0060670
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nudE neurodevelopment protein 1 like 1","termid":"PBO:0060670"}


id: GO:0032832
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune effector process","termid":"GO:0002697"},{"relation_name":"is_a","term_name":"regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation","termid":"GO:0032829"},{"relation_name":"is_a","term_name":"regulation of immune response","termid":"GO:0050776"},{"relation_name":"regulates","term_name":"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response","termid":"GO:0002298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response","synonyms":[{"name":"regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response","type":"related"},{"name":"regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response","type":"related"},{"name":"regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response","type":"related"},{"name":"regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response","type":"related"},{"name":"regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response","type":"related"}],"termid":"GO:0032832"}


id: GO:1903943
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:8649852"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of epithelial cell apoptotic process","termid":"GO:1904035"},{"relation_name":"regulates","term_name":"hepatocyte apoptotic process","termid":"GO:0097284"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of hepatocyte apoptotic process","synonyms":[{"name":"regulation of hepatocyte apoptosis","type":"narrow"}],"termid":"GO:1903943"}


id: GO:0046779
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed.","definition_xrefs":["PMID:11598019"],"gene_count":0,"genotype_count":0,"name":"obsolete suppression by virus of expression of host genes with introns (obsolete GO:0046779)","synonyms":[{"name":"negative regulation by virus of expression of host genes with introns","type":"exact"},{"name":"viral inhibition of expression of host genes with introns","type":"exact"}],"termid":"GO:0046779"}


id: GO:1901053
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of sarcosine.","definition_xrefs":["PMID:17951379","GOC:yaf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified amino acid catabolic process","termid":"GO:0042219"},{"relation_name":"is_a","term_name":"non-proteinogenic amino acid catabolic process","termid":"GO:0170044"},{"relation_name":"is_a","term_name":"sarcosine metabolic process","termid":"GO:1901052"},{"relation_name":"is_a","term_name":"alpha-amino acid catabolic process","termid":"GO:1901606"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0044248","GO:0008150"],"is_obsolete":false,"name":"sarcosine catabolic process","synonyms":[{"name":"sarcosine breakdown","type":"exact"},{"name":"sarcosine catabolism","type":"exact"},{"name":"sarcosine degradation","type":"exact"}],"termid":"GO:1901053"}


id: PBO:0005247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone H4-like TAF Taf6, SAGA complex subunit","termid":"PBO:0005247"}


id: PBO:0065115
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein kinase C iota","termid":"PBO:0065115"}


id: GO:1990014
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).","definition_xrefs":["PMID:22718347","NIF_Subcellular:sao1747012216"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"plasma membrane","termid":"GO:0005886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"orthogonal array","synonyms":[{"name":"OAP","type":"related"},{"name":"orthogonal array of particles","type":"exact"},{"name":"square array","type":"related"}],"termid":"GO:1990014"}


id: PATO:0002141
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A density quality which lacks pattern.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mass density","termid":"PATO:0001019"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"irregular density","termid":"PATO:0002141"}


id: PBO:0084294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation","termid":"PBO:0084294"}


id: GO:0036455
data:
  {"annotated_genes":["SJAG_03701"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[117672],"is_not":false,"summary":null,"term":"GO:0036455"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).","definition_xrefs":["GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase activity, transferring sulphur-containing groups","termid":"GO:0016782"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03701":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016782"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016782","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"iron-sulfur transferase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-2564828"],"synonyms":[{"name":"Fe-S transferase activity","type":"exact"}],"termid":"GO:0036455","terms_by_termid":{"GO:0036455":null}}


id: PBO:0067808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 110","termid":"PBO:0067808"}


id: PBO:0052185
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium two pore domain channel subfamily K member 17","termid":"PBO:0052185"}


id: PBO:0083543
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ribosomal protein gene RPL21A/YBR191W","termid":"PBO:0083543"}


id: GO:0042352
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).","definition_xrefs":["GOC:ma"],"direct_ancestors":[{"relation_name":"is_a","term_name":"GDP-L-fucose biosynthetic process","termid":"GO:0042350"},{"relation_name":"is_a","term_name":"nucleotide salvage","termid":"GO:0043173"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"GDP-L-fucose salvage","secondary_identifiers":["MetaCyc:PWY-6"],"synonyms":[{"name":"GDP-L-fucose biosynthesis, salvage pathway","type":"exact"},{"name":"GDP-L-fucose biosynthetic process, salvage pathway","type":"exact"}],"termid":"GO:0042352"}


id: PR:Q10153
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A CDP-diacylglycerol--inositol 3-phosphatidyltransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR15362:SF2","OMA:SCHPO00257","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDP-diacylglycerol--inositol 3-phosphatidyltransferase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1D4.08","secondary_identifiers":["UniProtKB:Q10153"],"synonyms":[{"name":"PI synthase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"PtdIns synthase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-CDIPT","type":"exact"},{"name":"phosphatidylinositol synthase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10153"}


id: GO:1901174
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of phytoene.","definition_xrefs":["UniPathway:UPA00799","GOC:yaf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carotene biosynthetic process","termid":"GO:0016120"},{"relation_name":"is_a","term_name":"phytoene metabolic process","termid":"GO:1901172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"phytoene biosynthetic process","synonyms":[{"name":"phytoene anabolism","type":"exact"},{"name":"phytoene biosynthesis","type":"exact"},{"name":"phytoene formation","type":"exact"},{"name":"phytoene synthesis","type":"exact"}],"termid":"GO:1901174"}


id: GO:0097159
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.","definition_xrefs":["PMID:7583672","GOC:sjw"],"gene_count":0,"genotype_count":0,"name":"obsolete organic cyclic compound binding (obsolete GO:0097159)","secondary_identifiers":["Reactome:R-HSA-1497796"],"termid":"GO:0097159"}


id: SO:0002124
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene that rearranges at the DNA level and codes the diversity region of the variable domain of an immunoglobuin (IG) gene.","definition_xrefs":["IGMT:http://www.imgt.org/IMGTScientificChart/SequenceDescription/Keywords.php","GENCODE:http://www.gencodegenes.org/gencode_biotypes.html"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immunoglobulin_gene","termid":"SO:0002122"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IG_D_gene","synonyms":[{"name":"IGD_gene","type":"exact"},{"name":"Immunoglobulin_Diversity_ gene","type":"exact"},{"name":"immunoglobulin_D_gene","type":"exact"}],"termid":"SO:0002124"}


id: GO:0090194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.","definition_xrefs":["GOC:tb","GOC:yaf","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of kidney development","termid":"GO:0090185"},{"relation_name":"is_a","term_name":"regulation of glomerulus development","termid":"GO:0090192"},{"relation_name":"negatively_regulates","term_name":"glomerulus development","termid":"GO:0032835"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of glomerulus development","termid":"GO:0090194"}


id: GO:0035253
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.","definition_xrefs":["PMID:12427867","GOC:cilia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cytoskeleton","termid":"GO:0005856"},{"relation_name":"part_of","term_name":"cilium","termid":"GO:0005929"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"ciliary rootlet","synonyms":[{"name":"cilial rootlet","type":"exact"},{"name":"cilium rootlet","type":"exact"}],"termid":"GO:0035253"}


id: PBO:0045728
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"E2F transcription factor 7","termid":"PBO:0045728"}


id: MONDO:0017502
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acheiria","termid":"MONDO:0017445"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"acheiria, unilateral","secondary_identifiers":["Orphanet:295101","icd11.foundation:1906312110"],"synonyms":[{"name":"congenital absence of hand, unilateral","type":"exact"}],"termid":"MONDO:0017502","xrefs":{"Monarch":{"xref_id":"0017502"}}}


id: PBO:0026733
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_protein_localization_to_kinetochore","termid":"PBO:0026733"}


id: PBO:0070035
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1332, pseudogene","termid":"PBO:0070035"}


id: PBO:0052854
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin associated protein 4-11","termid":"PBO:0052854"}


id: MONDO:0003267
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete myxopapillary ependymoma (obsolete MONDO:0003267)","termid":"MONDO:0003267","xrefs":{"Monarch":{"xref_id":"0003267"}}}


id: PATO:0001019
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A physical quality which inheres in a bearer by virtue of some influence is exerted by the bearer's mass per unit size.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"physical quality","termid":"PATO:0001018"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mass density","synonyms":[{"name":"density","type":"related"}],"termid":"PATO:0001019"}


id: GO:0016213
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-CoA and add a fourth double bond (a (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA).","definition_xrefs":["PMID:7212717","PMID:12713571","EC:1.14.19.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA desaturase activity","termid":"GO:0016215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"linoleoyl-CoA desaturase activity","secondary_identifiers":["Reactome:R-HSA-2046084","Reactome:R-HSA-2046097","Reactome:R-HSA-2046099","MetaCyc:1.14.19.3-RXN","Reactome:R-HSA-2046096"],"synonyms":[{"name":"delta(6)-acyl CoA desaturase activity","type":"broad"},{"name":"delta(6)-desaturase activity","type":"broad"},{"name":"delta(6)-fatty acyl-CoA desaturase activity","type":"broad"},{"name":"delta6-acyl CoA desaturase activity","type":"related"},{"name":"delta6-desaturase activity","type":"related"},{"name":"delta6-fatty acyl-CoA desaturase activity","type":"related"},{"name":"fatty acid 6-desaturase activity","type":"broad"},{"name":"fatty acid delta(6)-desaturase activity","type":"broad"},{"name":"fatty acid delta6-desaturase activity","type":"related"},{"name":"linoleate desaturase activity","type":"related"},{"name":"linoleic acid desaturase activity","type":"related"},{"name":"linoleic desaturase activity","type":"related"},{"name":"linoleoyl CoA desaturase activity","type":"exact"},{"name":"linoleoyl-coenzyme A desaturase activity","type":"exact"},{"name":"long-chain fatty acid delta(6)-desaturase activity","type":"broad"},{"name":"long-chain fatty acid delta6-desaturase activity","type":"related"}],"termid":"GO:0016213"}


id: FYPO:0006268
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone H3-K9 dimethylation during vegetative growth","termid":"FYPO:0000873"},{"relation_name":"is_a","term_name":"increased histone H3-K9 methylation at protein coding gene during vegetative growth","termid":"FYPO:0003102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0002494","FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0002274"],"is_obsolete":false,"name":"increased histone H3-K9 dimethylation at protein coding gene during vegetative growth","synonyms":[{"name":"increased histone H3 K9 dimethylation at protein coding gene during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 dimethylation at protein coding gene during mitotic cell cycle","type":"related"},{"name":"increased histone H3-K9 dimethylation at protein-coding gene during vegetative growth","type":"exact"},{"name":"increased histone H3K9me2 at protein coding gene during vegetative growth","type":"exact"},{"name":"increased histone lysine H3 K9 dimethylation at protein coding gene during vegetative growth","type":"exact"}],"termid":"FYPO:0006268"}


id: PBO:0076314
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synemin","termid":"PBO:0076314"}


id: MOD:01841
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links either two or an L-cysteine residue and an L-serine residue by a thioether bond to form a lanthionine, either D- or L- or meso-lanthionine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-carbon thioether crosslinked residues","termid":"MOD:01993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"lanthionine","synonyms":[{"name":"2,6-diamino-4-thiaheptanedioic acid","type":"exact"},{"name":"2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid","type":"exact"},{"name":"3,3'-thiobis-(2-aminopropanoic acid)","type":"exact"},{"name":"3,3'-thiobis-L-alanine","type":"exact"},{"name":"S-(2-amino-2-carboxyethyl)-L-cysteine","type":"exact"},{"name":"bis(2-amino-2-carboxyethyl)sulfanediyl","type":"exact"},{"name":"bis(2-amino-2-carboxyethyl)sulfide","type":"exact"}],"termid":"MOD:01841"}


id: MONDO:0859690
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"malignant adenoma","termid":"MONDO:0850125"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"malignant cystadenoma","secondary_identifiers":["DOID:60004"],"termid":"MONDO:0859690","xrefs":{"Monarch":{"xref_id":"0859690"}}}


id: PBO:0075555
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPEM family member 3","termid":"PBO:0075555"}


id: PBO:0058675
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6803","termid":"PBO:0058675"}


id: PBO:0001130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromodomain protein Swi6","termid":"PBO:0001130"}


id: GO:0021811
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex.","definition_xrefs":["GOC:dph","GOC:cls","GOC:jid","PMID:12626695","GO_REF:0000021","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"motogenic signaling initiating cell movement in cerebral cortex","termid":"GO:0021807"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration","synonyms":[{"name":"growth factor signaling initiating cell movement involved in cerebral cortex glial-mediated radial migration","type":"exact"},{"name":"growth factor signalling initiating cell movement involved in cerebral cortex glial-mediated radial migration","type":"exact"}],"termid":"GO:0021811"}


id: PBO:0081823
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 746","termid":"PBO:0081823"}


id: PBO:0051008
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin superfamily DCC subclass member 3","termid":"PBO:0051008"}


id: PBO:0066762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 60","termid":"PBO:0066762"}


id: PBO:0087135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p","termid":"PBO:0087135"}


id: MONDO:0030543
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"combined oxidative phosphorylation deficiency","termid":"MONDO:0000732"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"combined oxidative phosphorylation deficiency 54","secondary_identifiers":["DOID:0070427","OMIM:619737","UMLS:C5676912","MEDGEN:1812715"],"synonyms":[{"name":"COXPD54","type":"exact"}],"termid":"MONDO:0030543","xrefs":{"Monarch":{"xref_id":"0030543"}}}


id: GO:0018545
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.","definition_xrefs":["UM-BBD_enzymeID:e0346"],"gene_count":0,"genotype_count":0,"name":"obsolete NAD(P)H nitroreductase activity (obsolete GO:0018545)","termid":"GO:0018545"}


id: MONDO:0024878
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma that arises from a pre-existing lower grade epithelial lesion, or as a result of a primary carcinoma that has spread to secondary sites, or due to a complication of a cancer treatment.","definition_xrefs":["NCIT:C36310"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"carcinoma","termid":"MONDO:0004993"},{"relation_name":"is_a","term_name":"carcinoma","termid":"MONDO:0004993"},{"relation_name":"is_a","term_name":"secondary malignant neoplasm","termid":"MONDO:0024881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"secondary carcinoma","secondary_identifiers":["MEDGEN:88450","UMLS:C0085668"],"synonyms":[{"name":"secondary carcinoma","type":"exact"}],"termid":"MONDO:0024878","xrefs":{"Monarch":{"xref_id":"0024878"}}}


id: FYPO:0000828
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which entry into the G1 phase of the mitotic cell cycle (exit from mitosis) begins earlier than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic G1 phase progression","termid":"FYPO:0000602"},{"relation_name":"is_a","term_name":"premature cell cycle phase transition","termid":"FYPO:0000827"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0000631"],"is_obsolete":false,"name":"premature mitotic G1 phase entry","synonyms":[{"name":"accelerated entry into G1","type":"related"},{"name":"advanced mitotic G1 phase entry","type":"exact"},{"name":"advanced mitotic G1 progression","type":"related"},{"name":"mitotic cell cycle advance in G1","type":"related"},{"name":"premature G1 phase entry during mitotic cell cycle","type":"exact"},{"name":"premature exit from mitosis","type":"exact"},{"name":"premature mitotic G1 phase entry during vegetative growth","type":"exact"}],"termid":"FYPO:0000828"}


id: GO:0051643
data:
  {"annotated_genes":["SJAG_04221","SJAG_01116","SJAG_03247","SJAG_02626","SJAG_01564","SJAG_03170","SJAG_00053","SJAG_01437","SJAG_01168","SJAG_04417","SJAG_04413"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117970,60048,61255,61758,111461,71550,97232,91239,90161],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061817"},{"annotations":[90162,104164],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051685"},{"annotations":[115012,106826],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990854"}]},"cv_name":"biological_process","definition":"Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle localization","termid":"GO:0051640"},{"relation_name":"part_of","term_name":"endoplasmic reticulum organization","termid":"GO:0007029"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00053":null,"SJAG_01116":null,"SJAG_01168":null,"SJAG_01437":null,"SJAG_01564":null,"SJAG_02626":null,"SJAG_03170":null,"SJAG_03247":null,"SJAG_04221":null,"SJAG_04413":null,"SJAG_04417":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"endoplasmic reticulum localization","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"ER localization","type":"exact"},{"name":"endoplasmic reticulum localisation","type":"exact"},{"name":"establishment and maintenance of ER localization","type":"exact"}],"termid":"GO:0051643","terms_by_termid":{"GO:0051685":null,"GO:0061817":null,"GO:1990854":null}}


id: MONDO:0033637
data:
  {"annotated_genes":["SJAG_02504"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85494],"is_not":false,"summary":null,"term":"MONDO:0033637"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial complex IV deficiency, nuclear-type","termid":"MONDO:0033885"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02504":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial complex 4 deficiency, nuclear type 7","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5436685","GARD:16406","DOID:0070494","MEDGEN:1754683","OMIM:619051"],"synonyms":[{"name":"MC4DN7","type":"exact"},{"name":"mitochondrial complex IV deficiency, nuclear type 7","type":"exact"}],"termid":"MONDO:0033637","terms_by_termid":{"MONDO:0033637":null},"xrefs":{"Monarch":{"xref_id":"0033637"}}}


id: MONDO:0007055
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare bone dysplasia characterized by short stature, short hands and feet, mild facial dysmorphism, and characteristic X-ray abnormalities of the hands.","definition_xrefs":["Orphanet:969"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acromelic dysplasia","termid":"MONDO:0019695"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Acromicric dysplasia","secondary_identifiers":["MEDGEN:78549","icd11.foundation:1006372687","MESH:C535662","OMIM:102370","SCTID:254090007","DOID:0111243","ICD9:756.59","NORD:725","UMLS:C0265287","GARD:7"],"synonyms":[{"name":"ACMICD","type":"related"},{"name":"Acromicric dysplasia","type":"exact"},{"name":"Acromicric skeletal dysplasia","type":"related"}],"termid":"MONDO:0007055","xrefs":{"Monarch":{"xref_id":"0007055"}}}


id: GO:0052333
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which an organism effects a change in the structure or function of the cell wall of a second organism, where the two organisms are in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete modification by organism of cell wall of other organism involved in symbiotic interaction (obsolete GO:0052333)","synonyms":[{"name":"metabolism by organism of cell wall of other organism","type":"related"},{"name":"modification by organism of cell wall of other organism during symbiotic interaction","type":"related"}],"termid":"GO:0052333"}


id: GO:0022606
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The specification and formation of the polarity of a cell along its proximal/distal axis.","definition_xrefs":["GOC:isa_complete"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of monopolar cell polarity","termid":"GO:0061162"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007163"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007163","GO:0008150"],"is_obsolete":false,"name":"establishment of proximal/distal cell polarity","termid":"GO:0022606"}


id: PBO:0077135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOR signaling pathway regulator","termid":"PBO:0077135"}


id: PBO:0055679
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipase H","termid":"PBO:0055679"}


id: PBO:0058964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"makorin ring finger protein 7, pseudogene","termid":"PBO:0058964"}


id: PBO:0047569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibroblast growth factor 20","termid":"PBO:0047569"}


id: MONDO:1011222
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Retinal detachment that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinal detachment, non-human animal","termid":"MONDO:1010321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"retinal detachment, domestic cat","secondary_identifiers":["OMIA:000275-9685"],"termid":"MONDO:1011222","xrefs":{"Monarch":{"xref_id":"1011222"}}}


id: MONDO:0019020
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"PANDAS is an acronym for Pediatric Autoimmune Neuropsychiatric Disorders Associated with a group A beta-hemolytic Streptococcal infection and applied to a subgroup of children with obsessive-compulsive disorder (OCD) and/or tic disorders.","definition_xrefs":["Orphanet:66624"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete postinfectious autoimmune disease with chorea (obsolete MONDO:0017647)","termid":"MONDO:0017647"},{"relation_name":"is_a","term_name":"autoimmune disorder of the nervous system","termid":"MONDO:0002977"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"PANDAS","secondary_identifiers":["MESH:C537163","GARD:7312","UMLS:C2931429","MEDGEN:419798"],"synonyms":[{"name":"paediatric autoimmune disorders associated with Streptococcus infections","type":"exact"},{"name":"paediatric autoimmune neuropsychiatric disorder associated with Streptococcus","type":"related"},{"name":"paediatric autoimmune neuropsychiatric disorders associated with Streptococcus infections","type":"exact"},{"name":"paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections","type":"related"},{"name":"pediatric autoimmune disorders associated with Streptococcus infections","type":"exact"},{"name":"pediatric autoimmune neuropsychiatric disorder associated with Streptococcus","type":"related"},{"name":"pediatric autoimmune neuropsychiatric disorders associated with Streptococcus infections","type":"exact"},{"name":"pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections","type":"related"}],"termid":"MONDO:0019020","xrefs":{"Monarch":{"xref_id":"0019020"}}}


id: GO:0046236
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mandelate metabolic process","termid":"GO:0018924"},{"relation_name":"is_a","term_name":"monocarboxylic acid biosynthetic process","termid":"GO:0072330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"mandelate biosynthetic process","synonyms":[{"name":"mandelate anabolism","type":"exact"},{"name":"mandelate biosynthesis","type":"exact"},{"name":"mandelate formation","type":"exact"},{"name":"mandelate synthesis","type":"exact"}],"termid":"GO:0046236"}


id: SO:0001604
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant within a CDS resulting in the loss of an amino acid from the resulting polypeptide.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polypeptide_sequence_variant","termid":"SO:0001603"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amino_acid_deletion","synonyms":[{"name":"amino acid deletion","type":"exact"}],"termid":"SO:0001604"}


id: MONDO:0045012
data:
  {"annotated_genes":["SJAG_04810","SJAG_02148","SJAG_02696","SJAG_04270","SJAG_03018","SJAG_00717","SJAG_03024","SJAG_02855","SJAG_03509","SJAG_01474","SJAG_04865"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85087],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010621"},{"annotations":[87000],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013310"},{"annotations":[85322,85323],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011503"},{"annotations":[85813],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008974"},{"annotations":[86505,86504],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009849"},{"annotations":[86373,86372],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011816"},{"annotations":[84827,84828],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012481"},{"annotations":[85544],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014793"},{"annotations":[86971],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010035"}]},"cv_name":"mondo","definition":"A disease that has its basis in the disruption of steroid metabolic process.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic disease","termid":"MONDO:0005066"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00717":null,"SJAG_01474":null,"SJAG_02148":null,"SJAG_02696":null,"SJAG_02855":null,"SJAG_03018":null,"SJAG_03024":null,"SJAG_03509":null,"SJAG_04270":null,"SJAG_04810":null,"SJAG_04865":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"steroid metabolism disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0268283","SCTID:28710006","MEDGEN:541265"],"synonyms":[{"name":"disorder of steroid metabolic process","type":"exact"},{"name":"disorder of steroid metabolism","type":"exact"},{"name":"steroid metabolic process disease","type":"exact"},{"name":"steroid metabolism disease","type":"exact"}],"termid":"MONDO:0045012","terms_by_termid":{"MONDO:0008974":null,"MONDO:0009849":null,"MONDO:0010035":null,"MONDO:0010621":null,"MONDO:0011503":null,"MONDO:0011816":null,"MONDO:0012481":null,"MONDO:0013310":null,"MONDO:0014793":null},"xrefs":{"Monarch":{"xref_id":"0045012"}}}


id: FYECO:0000294
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"A sequential growth condition in which cells are first grown at a high temperature followed by growth at low temperature.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping sequential growth conditions","termid":"FYECO:0000094"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"temperature shift, high to low","termid":"FYECO:0000294"}


id: PBO:0039561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 54","termid":"PBO:0039561"}


id: PBO:0091244
data:
  {"annotation_feature_type":"gene","cv_name":"cat_act","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kcat/KM 2.1x10^4 min-1 M-1","termid":"PBO:0091244"}


id: GO:0001823
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.","definition_xrefs":["GOC:dph","PMID:10535314","ISBN:0721662544","ISBN:0124020607"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney development","termid":"GO:0001822"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephros development","synonyms":[{"name":"Wolffian body development","type":"exact"}],"termid":"GO:0001823"}


id: SO:0000846
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region of sequence which is a promoter for RNA polymerase III type 2.","definition_xrefs":["SO:ke"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000846 RNApol_III_promoter_type_2_region (obsolete SO:0000846)","termid":"SO:0000846"}


id: PBO:0078377
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"triggering receptor expressed on myeloid cells like 1","termid":"PBO:0078377"}


id: PBO:0036040
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_SRP-dependent_cotranslational_protein_targeting_to_membrane_during_vegetative_growth","termid":"PBO:0036040"}


id: PBO:0057161
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 302f","termid":"PBO:0057161"}


id: PBO:0024475
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human USB1","termid":"PBO:0024475"}


id: PBO:0078669
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Lys (anticodon TTT) 3-4","termid":"PBO:0078669"}


id: PBO:0081375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNF213 antisense RNA 1 (head to head)","termid":"PBO:0081375"}


id: MONDO:0007897
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete leukemia, chronic lymphocytic (obsolete MONDO:0007897)","termid":"MONDO:0007897","xrefs":{"Monarch":{"xref_id":"0007897"}}}


id: PBO:0002767
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PINT/PCI domain","termid":"PBO:0002767"}


id: GO:0044668
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).","definition_xrefs":["GOC:crds"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium:dicarboxylate symporter activity","termid":"GO:0017153"},{"relation_name":"is_a","term_name":"malonate(1-) transmembrane transporter activity","termid":"GO:1901239"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"sodium:malonate symporter activity","secondary_identifiers":["RHEA:33135"],"termid":"GO:0044668"}


id: GO:1901398
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation.","definition_xrefs":["GOC:sl","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transforming growth factor beta3 activation (obsolete GO:1901398)","synonyms":[{"name":"regulation of TGF-beta 3 activation","type":"exact"},{"name":"regulation of TGFB3 activation","type":"exact"},{"name":"regulation of TGFbeta 3 activation","type":"exact"}],"termid":"GO:1901398"}


id: GO:1902244
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving cis-abienol.","definition_xrefs":["PMID:22672125","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diterpenoid metabolic process","termid":"GO:0016101"},{"relation_name":"is_a","term_name":"tertiary alcohol metabolic process","termid":"GO:1902644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0006629","GO:0008150"],"is_obsolete":false,"name":"cis-abienol metabolic process","synonyms":[{"name":"cis-abienol metabolism","type":"exact"}],"termid":"GO:1902244"}


id: MONDO:0022622
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital disorder of glycosylation","termid":"MONDO:0015286"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0024322"],"is_obsolete":false,"name":"congenital disorder of glycosylation syndrome type 4","secondary_identifiers":["GARD:1174"],"synonyms":[{"name":"CDG syndrome type 4","type":"exact"},{"name":"congenital disorder of glycosylation syndrome type 4","type":"exact"}],"termid":"MONDO:0022622","xrefs":{"Monarch":{"xref_id":"0022622"}}}


id: PBO:0076259
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SVIL antisense RNA 1","termid":"PBO:0076259"}


id: MONDO:0017675
data:
  {"annotated_genes":["SJAG_05011"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84785],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007858"}]},"cv_name":"mondo","definition":"A palmoplantar keratosis characterized by keratoses with a \\\"raindrop\\\" pattern on the palmoplantar surface, skin lesions which may involve the whole of the palmoplantar surface, or may be more restricted in their distribution.","definition_xrefs":["Wikipedia:Palmoplantar_keratoderma#Punctate","DOID:0060361"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary palmoplantar keratoderma","termid":"MONDO:0019272"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05011":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"punctate palmoplantar keratoderma","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1212361548","GARD:21297","MEDGEN:870406","Orphanet:307967","SCTID:402773000","UMLS:C4024851"],"synonyms":[{"name":"punctate PPK","type":"exact"},{"name":"punctate keratosis palmoplantaris","type":"exact"},{"name":"punctate palmoplantar hyperkeratosis","type":"exact"}],"termid":"MONDO:0017675","terms_by_termid":{"MONDO:0007858":null},"xrefs":{"Monarch":{"xref_id":"0017675"}}}


id: GO:0004967
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.","definition_xrefs":["GOC:signaling","GOC:mah","PMID:22438981"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled peptide receptor activity","termid":"GO:0008528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"glucagon receptor activity","termid":"GO:0004967"}


id: FYPO:0001854
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to iron ions. All genes, or a specific subset of genes, may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased transcription during vegetative growth","termid":"FYPO:0000780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000294","FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0006551"],"is_obsolete":false,"name":"increased transcription during cellular response to iron","synonyms":[{"name":"increased transcription during cellular response to iron during mitotic cell cycle","type":"related"},{"name":"increased transcription during cellular response to iron during vegetative growth","type":"exact"},{"name":"increased transcription during cellular response to iron ion","type":"exact"},{"name":"increased transcription during cellular response to iron ions","type":"exact"}],"termid":"FYPO:0001854"}


id: PBO:0041288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complement C1r","termid":"PBO:0041288"}


id: PBO:0116708
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene)","termid":"PBO:0116708"}


id: GO:0008721
data:
  {"annotated_genes":["SJAG_04827"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[78601],"is_not":false,"summary":null,"term":"GO:0008721"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: D-serine = pyruvate + NH3.","definition_xrefs":["EC:4.3.1.18"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ammonia-lyase activity","termid":"GO:0016841"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04827":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"D-serine ammonia-lyase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-9014741","Reactome:R-HSA-9034539","MetaCyc:DSERDEAM-RXN","RHEA:13977"],"synonyms":[{"name":"D-hydroxy amino acid dehydratase activity","type":"broad"},{"name":"D-hydroxyaminoacid dehydratase activity","type":"related"},{"name":"D-serine ammonia-lyase (pyruvate-forming)","type":"related"},{"name":"D-serine deaminase activity","type":"related"},{"name":"D-serine dehydrase activity","type":"related"},{"name":"D-serine dehydratase (deaminating) activity","type":"related"},{"name":"D-serine dehydratase activity","type":"related"},{"name":"D-serine dehydration activity","type":"related"},{"name":"D-serine hydro-lyase (deaminating) activity","type":"related"},{"name":"D-serine hydrolase activity","type":"related"}],"termid":"GO:0008721","terms_by_termid":{"GO:0008721":null}}


id: PBO:0030667
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_27S_rRNA_precursor_level","termid":"PBO:0030667"}


id: MONDO:0012195
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Distal arthrogryposis type 4 is an inherited developmental defect syndrome characterized by multiple congenital contractures of limbs, without primary neurologic and/or muscle disease that affects limb function, and a mild to severe scoliosis. Intelligence is normal.","definition_xrefs":["Orphanet:65720"],"direct_ancestors":[{"relation_name":"is_a","term_name":"distal arthrogryposis","termid":"MONDO:0019942"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis-severe scoliosis syndrome","secondary_identifiers":["MEDGEN:373169","SCTID:715575001","UMLS:C1836756","OMIM:609128","GARD:16672","MESH:C563791","DOID:0111610"],"synonyms":[{"name":"DA4","type":"related"},{"name":"arthrogryposis with Severe scoliosis","type":"related"},{"name":"arthrogryposis, distal, type 2D","type":"related"},{"name":"arthrogryposis, distal, type 4","type":"related"},{"name":"distal arthrogryposis type 4","type":"exact"},{"name":"distal arthrogryposis type IID","type":"exact"}],"termid":"MONDO:0012195","xrefs":{"Monarch":{"xref_id":"0012195"}}}


id: PBO:0038711
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin gamma 1 pseudogene 6","termid":"PBO:0038711"}


id: GO:0007449
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.","definition_xrefs":["GOC:jid","ISBN:0879694238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"imaginal disc pattern formation","termid":"GO:0007447"},{"relation_name":"is_a","term_name":"proximal/distal pattern formation","termid":"GO:0009954"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"proximal/distal pattern formation, imaginal disc","termid":"GO:0007449"}


id: MONDO:0019454
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A myelodysplastic syndrome characterized by the presence of 5-19% myeloblasts in the bone marrow or 2-19% blasts in the peripheral blood. It includes two categories: myelodysplastic syndrome with excess blasts-1 and myelodysplastic syndrome with excess blasts-2.","definition_xrefs":["NCIT:C7506"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myelodysplastic syndrome","termid":"MONDO:0018881"},{"relation_name":"is_a","term_name":"hematopoietic and lymphoid cell neoplasm","termid":"MONDO:0044881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"myelodysplastic syndrome with excess blasts","secondary_identifiers":["MESH:D000754","GARD:19070","EFO:0003811","MedDRA:10038270","MEDGEN:8066","SCTID:398623004","UMLS:C0002894","ICDO:9983/3","Orphanet:86839"],"synonyms":[{"name":"MDS-EB","type":"exact"},{"name":"RAEB","type":"exact"},{"name":"myelodysplastic syndrome with Excess blasts","type":"exact"},{"name":"refractory Anaemia with Excess blasts","type":"exact"},{"name":"refractory Anaemia with an Excess of blasts","type":"exact"},{"name":"refractory Anemia with Excess blasts","type":"exact"},{"name":"refractory Anemia with an Excess of blasts","type":"exact"}],"termid":"MONDO:0019454","xrefs":{"Monarch":{"xref_id":"0019454"}}}


id: MONDO:0850102
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune disease","termid":"MONDO:0007179"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"non-specific autoimmune supratentorial encephalitis with characteristic antibodies","secondary_identifiers":["GARD:22497","UMLS:C5680408","Orphanet:624166","MEDGEN:1842219"],"termid":"MONDO:0850102","xrefs":{"Monarch":{"xref_id":"0850102"}}}


id: MONDO:1012862
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any paroxysmal dyskinesia that occurs in dogs due to a mutation in the SOD1 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"paroxysmal dyskinesia, dog","termid":"MONDO:1010422"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paroxysmal dyskinesia, SOD1-related, dog","secondary_identifiers":["OMIA:002322-9615"],"termid":"MONDO:1012862","xrefs":{"Monarch":{"xref_id":"1012862"}}}


id: GO:0046251
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.","definition_xrefs":["PMID:10224006"],"direct_ancestors":[{"relation_name":"is_a","term_name":"limonene metabolic process","termid":"GO:0018923"},{"relation_name":"is_a","term_name":"monoterpene catabolic process","termid":"GO:0043694"},{"relation_name":"is_a","term_name":"olefinic compound catabolic process","termid":"GO:0120256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"limonene catabolic process","synonyms":[{"name":"limonene breakdown","type":"exact"},{"name":"limonene catabolism","type":"exact"},{"name":"limonene degradation","type":"exact"}],"termid":"GO:0046251"}


id: GO:1903849
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.","definition_xrefs":["PMID:22269326","GOC:BHF","GOC:BHF_miRNA","GOC:rph","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of aorta morphogenesis","termid":"GO:1903847"},{"relation_name":"is_a","term_name":"positive regulation of artery morphogenesis","termid":"GO:1905653"},{"relation_name":"positively_regulates","term_name":"aorta morphogenesis","termid":"GO:0035909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of aorta morphogenesis","synonyms":[{"name":"activation of aorta morphogenesis","type":"narrow"},{"name":"up regulation of aorta morphogenesis","type":"exact"},{"name":"up-regulation of aorta morphogenesis","type":"exact"},{"name":"upregulation of aorta morphogenesis","type":"exact"}],"termid":"GO:1903849"}


id: PBO:0080514
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WASF1 pseudogene 1","termid":"PBO:0080514"}


id: GO:1990321
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.","definition_xrefs":["PMID:17876790","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"FACIT collagen trimer","termid":"GO:0005593"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"collagen type XXII trimer","termid":"GO:1990321"}


id: GO:0075261
data:
  {"annotated_genes":["SJAG_03501"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[118041],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0075319"}]},"cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"is_a","term_name":"regulation of spore-bearing organ development","termid":"GO:0075260"},{"relation_name":"is_a","term_name":"positive regulation of reproductive process","termid":"GO:2000243"},{"relation_name":"positively_regulates","term_name":"spore-bearing structure development","termid":"GO:0075259"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03501":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of spore-bearing organ development","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0075261","terms_by_termid":{"GO:0075319":null}}


id: PBO:0055108
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2526","termid":"PBO:0055108"}


id: PBO:0055842
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LRIG2 divergent transcript","termid":"PBO:0055842"}


id: MONDO:0012788
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"excluded_subClassOf","term_name":"coronary artery disorder","termid":"MONDO:0005010"},{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coronary heart disease, susceptibility to, 9","secondary_identifiers":["MEDGEN:436983","OMIM:612030","UMLS:C2677580"],"synonyms":[{"name":"CHDS9","type":"exact"},{"name":"coronary heart disease, susceptibility to, 9","type":"exact"}],"termid":"MONDO:0012788","xrefs":{"Monarch":{"xref_id":"0012788"}}}


id: MONDO:0016318
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Progressive multifocal leukoencephalopathy (PML) is a neurological disorder that damages the myelin that covers and protects nerves in the white matter of the brain. It is caused by the JC virus (JCV). By age 10, most people have been infected with this virus, but itrarelycauses symptoms unless the immune system becomes severely weakened.The disease occurs, rarely, in organ transplant patients; people undergoing chronic corticosteroid or immunosuppressive therapy; and individuals with cancer, such as Hodgkins disease, lymphoma, and sarcoidosis. PML is most common among individuals with acquired immune deficiency syndrome (AIDS).","direct_ancestors":[{"relation_name":"is_a","term_name":"infectious encephalitis","termid":"MONDO:0020067"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progressive multifocal leukoencephalopathy","secondary_identifiers":["ICD10CM:A81.2","GARD:7468","icd11.foundation:902939755","MESH:D007968","MedDRA:10036807","MEDGEN:7327","NANDO:1200205","NCIT:C26815","EFO:0007455","DOID:643","UMLS:C0023524","ICD9:046.3","Orphanet:217260","SCTID:22255007","NORD:1616"],"synonyms":[{"name":"PML","type":"exact"},{"name":"leukoencephalopathy, progressive multifocal","type":"related"},{"name":"progressive multifocal leukoencephalitis","type":"exact"}],"termid":"MONDO:0016318","xrefs":{"Monarch":{"xref_id":"0016318"}}}


id: PBO:0043410
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CKLF like MARVEL transmembrane domain containing 7","termid":"PBO:0043410"}


id: PBO:0084228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Htz1p-binding component of the SWR1 complex; exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; may function as a lock that prevents removal of H2AZ from nucleosomes; required for vacuolar protein sorting","termid":"PBO:0084228"}


id: PBO:0003304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"human COMT homolog 1","termid":"PBO:0003304"}


id: MOD:00318
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-cysteine residue and an L-tryptophan residue by a thioether bond to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone.","definition_xrefs":["PubMed:11717396","RESID:AA0313","PubMed:11555656"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thioether crosslinked residues","termid":"MOD:00687"},{"relation_name":"is_a","term_name":"crosslinked L-tryptophan residue","termid":"MOD:02057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"4'-(S-L-cysteinyl)-L-tryptophyl quinone","synonyms":[{"name":"(2R)-2-amino-3-[(3-[(2S)-2-amino-2-carboxyethyl]-6,7-dioxo-6,7-dihydro-1H-indol-4-yl)sulfanyl]propanoic acid","type":"exact"},{"name":"3-(2-amino-2-carboxyethyl)-4-[2-amino-2-carboxyethyl]sulfanyl-6,7-indolinedione","type":"exact"},{"name":"4'-(L-cystein-S-yl)-L-tryptophyl quinone","type":"exact"},{"name":"4-(S-cysteinyl)tryptophan-6,7-dione","type":"exact"},{"name":"CROSSLNK 4'-cysteinyl-tryptophylquinone (Cys-Trp)","type":"exact"},{"name":"CTQ","type":"exact"},{"name":"cysteine tryptophylquinone","type":"exact"}],"termid":"MOD:00318"}


id: PBO:0027364
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_DNA_damage_during_mitotic_S_phase","termid":"PBO:0027364"}


id: PBO:0087977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA 3'-end processing endonuclease tRNase Z; also localized to mitochondria and interacts genetically with Rex2 exonuclease; homolog of the human candidate prostate cancer susceptibility gene ELAC2","termid":"PBO:0087977"}


id: GO:0102235
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-penten-3-one + NADPH + H+ = 1-pentan-3-one + NADP.","definition_xrefs":["GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"1-penten-3-one reductase activity","secondary_identifiers":["MetaCyc:RXN-12295"],"termid":"GO:0102235"}


id: PBO:0043427
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclic nucleotide gated channel subunit beta 1","termid":"PBO:0043427"}


id: FYPO:0007532
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which arrested replication forks do not colocalize with nuclear pore complexes (NPCs) longer than actively replicating forks. Normally, arrested replication forks relocate to NPCs as part of replication fork processing, and remain anchored at NPCs while recombination-dependent replication takes place.","definition_xrefs":["PMID:33159083","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal replication fork processing","termid":"FYPO:0003586"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000293"],"is_obsolete":false,"name":"decreased replication fork colocalization with nuclear pore complex","synonyms":[{"name":"decreased replication fork colocalization with NPC","type":"exact"},{"name":"decreased replication fork colocalization with nuclear pore","type":"exact"},{"name":"decreased replication fork colocalization with nuclear pore complex during mitotic S phase","type":"exact"},{"name":"decreased replication fork colocalization with nuclear pore complex during mitotic cell cycle","type":"related"},{"name":"decreased replication fork colocalization with nuclear pore complex during vegetative growth","type":"exact"},{"name":"decreased replication fork relocation to nuclear pore complex","type":"exact"},{"name":"decreased replication fork relocation to nuclear pore complex during mitotic S phase","type":"exact"},{"name":"reduced replication fork colocalization with nuclear pore complex","type":"exact"}],"termid":"FYPO:0007532"}


id: MONDO:0043839
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.","definition_xrefs":["MESH:D014456"],"direct_ancestors":[{"relation_name":"is_a","term_name":"human disease","termid":"MONDO:0700096"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ulcer disease","secondary_identifiers":["NCIT:C3426","SCTID:429040005","UMLS:C0041582","MEDGEN:22541"],"synonyms":[{"name":"ulcer","type":"exact"},{"name":"ulcers","type":"exact"}],"termid":"MONDO:0043839","xrefs":{"Monarch":{"xref_id":"0043839"}}}


id: PBO:0040604
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BAGE family member 2, pseudogene","termid":"PBO:0040604"}


id: PBO:0086344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pseudouridine synthase; catalyzes pseudouridylation at positions 35 and 56 in U2 snRNA, position 50 in 5S rRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); also pseudouridylates some mRNAs; relocates from nucleus to cytoplasm during heat shock and differentially modifies some mRNAs during heat shock; conserved in archaea, vertebrates, and some bacteria","termid":"PBO:0086344"}


id: MONDO:0018875
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare cancer predisposition syndrome characterized by the early-onset of multiple primary cancers such as breast cancer, soft tissue and bone sarcomas, brain tumors and adrenal cortical carcinoma (ACC).","definition_xrefs":["Orphanet:524"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"Li-Fraumeni syndrome","secondary_identifiers":["OMIM:609266","MESH:D016864","UMLS:C0085390","MedDRA:10066795","OMIM:151623","SCTID:428850001","GARD:6902","DOID:3012","ICD9:V84.01","DOID:0111503","icd11.foundation:1968061860","MEDGEN:88399","NORD:1913","NCIT:C3476"],"synonyms":[{"name":"LFS","type":"exact"},{"name":"LFS1","type":"related"},{"name":"LFS3","type":"related"},{"name":"Li Fraumeni syndrome","type":"exact"},{"name":"Li-Fraumeni familial cancer susceptibility syndrome","type":"exact"},{"name":"Li-Fraumeni familiar cancer susceptibility syndrome","type":"exact"},{"name":"Li-Fraumeni syndrome","type":"exact"},{"name":"Li-Fraumeni syndrome caused by mutation in TP53","type":"exact"},{"name":"Li-Fraumeni-like syndrome","type":"related"},{"name":"SBLA syndrome","type":"exact"},{"name":"SBLA syndrome (sarcoma, breast, leukemia, and adrenal gland)","type":"related"},{"name":"TP53 Li-Fraumeni syndrome","type":"exact"},{"name":"sarcoma family syndrome of 51 and Fraumeni","type":"related"},{"name":"sarcoma family syndrome of Li and Fraumeni","type":"related"},{"name":"sarcoma, breast, leukaemia and adrenal gland syndrome","type":"exact"},{"name":"sarcoma, breast, leukemia and adrenal gland syndrome","type":"exact"}],"termid":"MONDO:0018875","xrefs":{"Monarch":{"xref_id":"0018875"}}}


id: MONDO:1011273
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any progressive retinal atrophy in dogs in which the cause of the disease is a mutation in the TTC8 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"progressive retinal atrophy, dog","termid":"MONDO:1012226"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progressive retinal atrophy, TTC8-related, dog","secondary_identifiers":["OMIA:001984-9615"],"termid":"MONDO:1011273","xrefs":{"Monarch":{"xref_id":"1011273"}}}


id: GO:1905918
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of CoA-transferase activity.","definition_xrefs":["GOC:bc","GOC:TermGenie","PMID:20164328","GO_REF:0000059","GOC:aruk"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of CoA-transferase activity (obsolete GO:1905918)","termid":"GO:1905918"}


id: GO:0070320
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binds to and stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"potassium channel inhibitor activity","termid":"GO:0019870"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0098772","GO:0003674","GO:0140678"],"is_obsolete":false,"name":"inward rectifier potassium channel inhibitor activity","termid":"GO:0070320"}


id: MONDO:0008340
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital ptosis is characterized by superior eyelid drop present at birth.","definition_xrefs":["Orphanet:91411"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ptosis","termid":"MONDO:0000728"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"ptosis, hereditary congenital, 1","secondary_identifiers":["MEDGEN:357987","MESH:C566737","MedDRA:10015996","NCIT:C27049","HP:0007970","DOID:0060261","OMIM:178300","SCTID:268163008","GARD:16798","ICD9:743.61","UMLS:C1867438"],"synonyms":[{"name":"PTOS1","type":"related"},{"name":"congenital eyelid ptosis","type":"exact"},{"name":"congenital ptosis","type":"exact"},{"name":"congenital ptosis (disease)","type":"exact"},{"name":"ptosis, congenital","type":"exact"},{"name":"ptosis, hereditary congenital 1","type":"related"},{"name":"ptosis, hereditary congenital, 1","type":"exact"}],"termid":"MONDO:0008340","xrefs":{"Monarch":{"xref_id":"0008340"}}}


id: PBO:0082747
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook; RSC1 has a paralog, RSC2, that arose from the whole genome duplication","termid":"PBO:0082747"}


id: PBO:0086032
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function containing WW and FF domains; overexpression causes accumulation of cells in G1 phase","termid":"PBO:0086032"}


id: GO:0140636
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which copper is transported from the cytosol into the mitochondrial matrix.","definition_xrefs":["PMID:32979421"],"direct_ancestors":[{"relation_name":"is_a","term_name":"copper ion transmembrane transport","termid":"GO:0035434"},{"relation_name":"is_a","term_name":"import into the mitochondrion","termid":"GO:0170036"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"copper import into the mitochondrion","termid":"GO:0140636"}


id: PBO:0068901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 143, pseudogene","termid":"PBO:0068901"}


id: MONDO:0005751
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute, febrile, infectious disease generally occurring in epidemics. It is usually caused by coxsackieviruses B and sometimes by coxsackieviruses A; echoviruses; or other enteroviruses.","definition_xrefs":["MESH:D011000"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral infectious disease","termid":"MONDO:0005108"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epidemic pleurodynia","secondary_identifiers":["MEDGEN:19355","DOID:10882","ICD9:074.1","SCTID:83264000","ICD10CM:B33.0","UMLS:C0032238"],"synonyms":[{"name":"Bamble disease","type":"exact"},{"name":"Bornholm disease","type":"exact"},{"name":"devil's grip","type":"exact"},{"name":"epidemic myalgia","type":"exact"},{"name":"epidemic pleurisy","type":"exact"},{"name":"epidemic, myositis","type":"exact"}],"termid":"MONDO:0005751","xrefs":{"Monarch":{"xref_id":"0005751"}}}


id: GO:0036369
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.","definition_xrefs":["PMID:22833559","GOC:vw","GOC:al"],"gene_count":0,"genotype_count":0,"name":"obsolete transcription factor catabolic process (obsolete GO:0036369)","synonyms":[{"name":"proteasome-mediated transcription factor catabolism","type":"exact"},{"name":"sequence-specific DNA binding transcription factor catabolic process","type":"exact"},{"name":"transcription factor breakdown","type":"exact"},{"name":"transcription factor catabolism","type":"exact"},{"name":"transcription factor degradation","type":"exact"}],"termid":"GO:0036369"}


id: GO:0042371
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.","definition_xrefs":["GOC:jl","PMID:24489112"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ketone biosynthetic process","termid":"GO:0042181"},{"relation_name":"is_a","term_name":"fat-soluble vitamin biosynthetic process","termid":"GO:0042362"},{"relation_name":"is_a","term_name":"vitamin K metabolic process","termid":"GO:0042373"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006766"}],"interesting_parent_ids":["GO:0044281","GO:0006766","GO:0008150"],"is_obsolete":false,"name":"vitamin K biosynthetic process","synonyms":[{"name":"naphthoquinone metabolic process","type":"broad"},{"name":"naphthoquinone metabolism","type":"broad"},{"name":"vitamin K anabolism","type":"exact"},{"name":"vitamin K biosynthesis","type":"exact"},{"name":"vitamin K formation","type":"exact"},{"name":"vitamin K synthesis","type":"exact"}],"termid":"GO:0042371"}


id: PBO:0087237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sequence-specific DNA binding protein; binds to a sequence motif associated with distinct genomic hotspots of non-H2B protein ubiquitylation (ub-hotspots); interacts with Slx5p to recruit the Slx5-Slx8  SUMO-targeted Ub ligase (STUbL) complex to ub-hotspots; deletion prevents ub-hotspot formation and exacerbates heat sensitivity of cells deficient in Rpd3L histone deacetylase complex members; forms nuclear foci upon DNA replication stress","termid":"PBO:0087237"}


id: GO:1990490
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea.","definition_xrefs":["GOC:mengo_curators","PMID:15473999","PMID:24650628"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proton-transporting two-sector ATPase complex","termid":"GO:0016469"},{"relation_name":"is_a","term_name":"ATPase complex","termid":"GO:1904949"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"archaeal proton-transporting A-type ATPase complex","synonyms":[{"name":"A-type ATPase protein complex","type":"broad"},{"name":"archaeal A-type ATPase protein complex","type":"broad"}],"termid":"GO:1990490"}


id: PBO:0049319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GS homeobox 1","termid":"PBO:0049319"}


id: FYPO:0006855
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which methylation of lysine at position 37 of histone H3 is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone methylation","termid":"FYPO:0006870"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0002274","FYPO:0002494"],"is_obsolete":false,"name":"abnormal histone H3-K37 methylation","synonyms":[{"name":"abnormal histone H3 K37 methylation","type":"exact"},{"name":"abnormal histone H3K37me","type":"exact"},{"name":"abnormal histone lysine H3 K37 methylation","type":"exact"}],"termid":"FYPO:0006855"}


id: GO:0072460
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of events in which information about whether recombination is complete is received and converted into a molecular signal, contributing to a meiotic recombination checkpoint.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete detection of stimulus involved in meiotic recombination checkpoint (obsolete GO:0072460)","synonyms":[{"name":"meiotic recombination checkpoint sensor mechanism","type":"related"},{"name":"meiotic recombination checkpoint sensor process","type":"related"},{"name":"sensing involved in meiotic recombination checkpoint","type":"related"}],"termid":"GO:0072460"}


id: PBO:0077700
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tenomodulin","termid":"PBO:0077700"}


id: PBO:0002030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha SNAP (predicted)","termid":"PBO:0002030"}


id: PBO:0089958
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ragulator complex Rag GEF subunit","termid":"PBO:0089958"}


id: PBO:0013465
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"similarity to YCL030C is at the C-term, S. pombe his7 is similar to YCl030C at the N-term","termid":"PBO:0013465"}


id: MONDO:1010808
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Polydactyly that occurs in rock pigeon.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bird disease","termid":"MONDO:0024905"},{"relation_name":"is_a","term_name":"polydactyly, non-human animal","termid":"MONDO:1010158"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polydactyly, rock pigeon","secondary_identifiers":["OMIA:000810-8932"],"termid":"MONDO:1010808","xrefs":{"Monarch":{"xref_id":"1010808"}}}


id: MONDO:0015825
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete obesity due to congenital leptin resistance (obsolete MONDO:0015825)","secondary_identifiers":["Orphanet:179490"],"termid":"MONDO:0015825","xrefs":{"Monarch":{"xref_id":"0015825"}}}


id: PBO:0004551
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally activates stress related genes","termid":"PBO:0004551"}


id: PBO:0029448
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_glutamate-ammonia_ligase_activity","termid":"PBO:0029448"}


id: GO:0035312
data:
  {"annotated_genes":["SJAG_05280","SJAG_04410","SJAG_01832","SJAG_01173","SJAG_03734","SJAG_01648"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70997,88140],"is_not":false,"summary":null,"term":"GO:0035312"},{"annotations":[76650],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033699"},{"annotations":[107559,96901],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051908"},{"annotations":[72248,96903],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045145"}]},"cv_name":"molecular_function","definition":"Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.","definition_xrefs":["ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"5'-3' exonuclease activity","termid":"GO:0008409"},{"relation_name":"is_a","term_name":"DNA exonuclease activity, producing 5'-phosphomonoesters","termid":"GO:0016895"}],"gene_count":6,"genes_by_uniquename":{"SJAG_01173":null,"SJAG_01648":null,"SJAG_01832":null,"SJAG_03734":null,"SJAG_04410":null,"SJAG_05280":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0004527"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0140097"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0140097","GO:0003674","GO:0016788","GO:0004527"],"is_obsolete":false,"name":"5'-3' DNA exonuclease activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"5'-3' exodeoxyribonuclease activity","type":"exact"}],"termid":"GO:0035312","terms_by_termid":{"GO:0033699":null,"GO:0035312":null,"GO:0045145":null,"GO:0051908":null}}


id: FYPO:0001098
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-nitroquinoline N-oxide. Cells stop growing (and may die) at a concentration of 4-nitroquinoline N-oxide that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0000139","FYPO:0001985","FYPO:0002683","FYPO:0005447"],"is_obsolete":false,"name":"sensitive to 4-nitroquinoline N-oxide","synonyms":[{"name":"hypersensitive to 4-nitroquinoline N-oxide","type":"exact"},{"name":"sensitive to 4-NQO","type":"exact"},{"name":"sensitive to 4-nitroquinoline N-oxide during mitotic cell cycle","type":"related"},{"name":"sensitive to 4-nitroquinoline N-oxide during vegetative growth","type":"exact"},{"name":"sensitive to 4NQO","type":"exact"}],"termid":"FYPO:0001098"}


id: PBO:0041195
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BUB3 mitotic checkpoint protein pseudogene 1","termid":"PBO:0041195"}


id: GO:0070355
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).","definition_xrefs":["PMID:7654227"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SNARE complex","termid":"GO:0031201"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005737"],"is_obsolete":false,"name":"synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex","synonyms":[{"name":"SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2, CPLX2)","type":"narrow"},{"name":"STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2-CPLX2 complex","type":"narrow"}],"termid":"GO:0070355"}


id: PBO:0001876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DASH complex subunit Dad1","termid":"PBO:0001876"}


id: MONDO:0011275
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare autosomal recessive acromesomelic dysplasia characterized by severe dwarfism (adult height >120 cm), both axial and appendicular involvement (shortening of the middle and distal segments of limbs and vertebral shortening), and with normal facial appearance and intelligence. It is a less severe form than acromesomelic dysplasia, Grebe type and acromesomelic dysplasia, Hunter-Thomson type.","definition_xrefs":["Orphanet:40"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acromesomelic dysplasia","termid":"MONDO:0019696"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"acromesomelic dysplasia 1, Maroteaux type","secondary_identifiers":["GARD:507","UMLS:C1864356","SCTID:718559000","DOID:0080050","MEDGEN:355199","MESH:C535661","OMIM:602875"],"synonyms":[{"name":"AMDM","type":"related"},{"name":"St. Helena dysplasia","type":"related"},{"name":"acromesomelic dwarfism Maroteux type","type":"related"},{"name":"acromesomelic dysplasia 1, Maroteaux type","type":"exact"},{"name":"acromesomelic dysplasia Maroteaux type","type":"related"},{"name":"acromesomelic dysplasia, Maroteaux type","type":"exact"}],"termid":"MONDO:0011275","xrefs":{"Monarch":{"xref_id":"0011275"}}}


id: GO:0140065
data:
  {"annotated_genes":["SJAG_02990"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[98755],"is_not":false,"summary":null,"term":"GO:0140065"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.","definition_xrefs":["PMID:27105113"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acyltransferase activity","termid":"GO:0016410"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02990":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0016746"],"is_obsolete":false,"name":"peptide butyryltransferase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["RHEA:53912"],"synonyms":[{"name":"protein butyryltransferase activity","type":"related"}],"termid":"GO:0140065","terms_by_termid":{"GO:0140065":null}}


id: GO:0000271
data:
  {"annotated_genes":["SJAG_01963","SJAG_01787","SJAG_00218","SJAG_01028","SJAG_04236","SJAG_01835","SJAG_05285","SJAG_00963","SJAG_04659","SJAG_04184","SJAG_04878","SJAG_03587","SJAG_04073","SJAG_04668","SJAG_02590","SJAG_02446","SJAG_01288","SJAG_04771","SJAG_01290","SJAG_03705","SJAG_04462","SJAG_01426","SJAG_03057","SJAG_00610","SJAG_01255","SJAG_02916","SJAG_04666","SJAG_04483","SJAG_03123","SJAG_02278","SJAG_00424","SJAG_00183","SJAG_01453","SJAG_02222","SJAG_04509","SJAG_01376","SJAG_00876"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[63110,76552,74857],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006078"},{"annotations":[93094,79090,100408,95010],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051072"},{"annotations":[94222],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034413"},{"annotations":[72696],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034412"},{"annotations":[70200,72934,71163,73072,78431],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070600"},{"annotations":[72698,105903,75498,74189,115628,70462,91352,112968],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071970"},{"annotations":[77917,102431],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070880"},{"annotations":[76913,78630],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0045719"},{"annotations":[87264,92179],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0140748"},{"annotations":[87642],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0032951"},{"annotations":[105143,117721,102633,117846,105715,90524,92163],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0090334"},{"annotations":[94698,102635,89186,92185],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0070610"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide metabolic process","termid":"GO:0005976"},{"relation_name":"is_a","term_name":"macromolecule biosynthetic process","termid":"GO:0009059"},{"relation_name":"is_a","term_name":"carbohydrate biosynthetic process","termid":"GO:0016051"}],"gene_count":37,"genes_by_uniquename":{"SJAG_00183":null,"SJAG_00218":null,"SJAG_00424":null,"SJAG_00610":null,"SJAG_00876":null,"SJAG_00963":null,"SJAG_01028":null,"SJAG_01255":null,"SJAG_01288":null,"SJAG_01290":null,"SJAG_01376":null,"SJAG_01426":null,"SJAG_01453":null,"SJAG_01787":null,"SJAG_01835":null,"SJAG_01963":null,"SJAG_02222":null,"SJAG_02278":null,"SJAG_02446":null,"SJAG_02590":null,"SJAG_02916":null,"SJAG_03057":null,"SJAG_03123":null,"SJAG_03587":null,"SJAG_03705":null,"SJAG_04073":null,"SJAG_04184":null,"SJAG_04236":null,"SJAG_04462":null,"SJAG_04483":null,"SJAG_04509":null,"SJAG_04659":null,"SJAG_04666":null,"SJAG_04668":null,"SJAG_04771":null,"SJAG_04878":null,"SJAG_05285":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"polysaccharide biosynthetic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"glycan biosynthesis","type":"exact"},{"name":"glycan biosynthetic process","type":"exact"},{"name":"polysaccharide anabolism","type":"exact"},{"name":"polysaccharide biosynthesis","type":"exact"},{"name":"polysaccharide formation","type":"exact"},{"name":"polysaccharide synthesis","type":"exact"}],"termid":"GO:0000271","terms_by_termid":{"GO:0006078":null,"GO:0032951":null,"GO:0034412":null,"GO:0034413":null,"GO:0045719":null,"GO:0051072":null,"GO:0070600":null,"GO:0070610":null,"GO:0070880":null,"GO:0071970":null,"GO:0090334":null,"GO:0140748":null}}


id: PBO:0081831
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 765","termid":"PBO:0081831"}


id: PBO:0028144
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_cell_population_growth_on_glycerol/ethanol_carbon_source","termid":"PBO:0028144"}


id: PBO:0073515
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SH3 domain binding glutamate rich protein","termid":"PBO:0073515"}


id: PBO:0072856
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"store-operated calcium entry associated regulatory factor","termid":"PBO:0072856"}


id: MONDO:1012436
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"lacrimal fistula, non-human animal","termid":"MONDO:1011993"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lacrimal fistula, cattle","secondary_identifiers":["OMIA:001693-9913"],"termid":"MONDO:1012436","xrefs":{"Monarch":{"xref_id":"1012436"}}}


id: PBO:0044684
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DDIT4L antisense RNA 1","termid":"PBO:0044684"}


id: PBO:0042771
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centrosomal protein 76","termid":"PBO:0042771"}


id: PBO:0081114
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZFAND3 divergent transcript","termid":"PBO:0081114"}


id: GO:0071064
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.","definition_xrefs":["PMID:10837471"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005886","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"alphaE-beta7 integrin-E-cadherin complex","synonyms":[{"name":"ITGAE-ITGB7-CDH1 complex","type":"narrow"}],"termid":"GO:0071064"}


id: GO:1901388
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.","definition_xrefs":["GOC:sl","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transforming growth factor beta activation (obsolete GO:1901388)","synonyms":[{"name":"regulation of L-TGF-beta activation","type":"exact"},{"name":"regulation of TGF-B activation","type":"exact"},{"name":"regulation of TGF-beta activation","type":"exact"},{"name":"regulation of TGFB activation","type":"exact"},{"name":"regulation of TGFbeta activation","type":"exact"},{"name":"regulation of latent TGF-beta activation","type":"exact"}],"termid":"GO:1901388"}


id: FYPO:0002459
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, septated, and elongated.","definition_xrefs":["PomBase:jh","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viable elongated vegetative cell","termid":"FYPO:0001492"},{"relation_name":"is_a","term_name":"branched, elongated, septated cell","termid":"FYPO:0004594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000005","FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0000004"],"is_obsolete":false,"name":"viable branched, elongated vegetative cell","secondary_identifiers":["FYPO:0002458"],"synonyms":[{"name":"viable branched cell during vegetative growth","type":"exact"},{"name":"viable branched elongated vegetative cell","type":"exact"},{"name":"viable branched vegetative cell","type":"exact"},{"name":"viable branched vegetative cell during mitotic cell cycle","type":"related"},{"name":"viable branched, elongated cell during vegetative growth","type":"exact"},{"name":"viable branched, elongated vegetative cell during mitotic cell cycle","type":"related"},{"name":"viable branched, elongated, septated cell","type":"exact"},{"name":"viable branched, long, septated cell","type":"exact"},{"name":"viable branched, septated cell","type":"exact"},{"name":"viable elongated branched cell","type":"exact"}],"termid":"FYPO:0002459"}


id: GO:0098793
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The part of a synapse that is part of the presynaptic cell.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"synapse","termid":"GO:0045202"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"presynapse","synonyms":[{"name":"presynaptic terminal","type":"exact"}],"termid":"GO:0098793"}


id: RO:0002379
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"x spatially_coextensive_with y if and inly if x and y have the same location","direct_ancestors":[{"relation_name":"is_a","term_name":"overlaps","termid":"RO:0002131"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spatially_coextensive_with","termid":"RO:0002379"}


id: GO:0021927
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.","definition_xrefs":["GO_REF:0000021","GOC:dph","GOC:jid","GOC:cls","GOC:dgh","PMID:15157725"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell proliferation in hindbrain ventricular zone","termid":"GO:0021923"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"deep nuclear neuron precursor proliferation","termid":"GO:0021927"}


id: GO:1990334
data:
  {"annotated_genes":["SJAG_01386","SJAG_04943"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[78586,99449],"is_not":false,"summary":null,"term":"GO:1990334"}]},"cv_name":"cellular_component","definition":"A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.","definition_xrefs":["PMID:16449187","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"GTPase activator complex","termid":"GO:1902773"},{"relation_name":"part_of","term_name":"spindle pole body","termid":"GO:0005816"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01386":null,"SJAG_04943":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005816"},{"rel_name":"part_of","termid":"GO:0015630"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0015630","GO:0032991","GO:0005816","GO:0005575"],"is_obsolete":false,"name":"Bfa1-Bub2 complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:1990334","terms_by_termid":{"GO:1990334":null}}


id: PBO:0042765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centrosomal protein 57 like 1 pseudogene 1","termid":"PBO:0042765"}


id: PATO:0001974
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape quality inhering in a bearer by virtue of the bearer's terminating in a round end, the centre of which is depressed.","definition_xrefs":["ISBN:0881923214"],"direct_ancestors":[{"relation_name":"is_a","term_name":"blunt","termid":"PATO:0001950"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"retuse","termid":"PATO:0001974"}


id: PBO:0065471
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome 26S subunit, non-ATPase, 10 pseudogene 2","termid":"PBO:0065471"}


id: GO:0006293
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.","definition_xrefs":["GOC:elh","PMID:10197977"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein-containing complex assembly","termid":"GO:0031334"},{"relation_name":"part_of","term_name":"nucleotide-excision repair","termid":"GO:0006289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0065003"},{"rel_name":"positively_regulates","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0006281"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0006281","GO:0065003","GO:0006259"],"is_obsolete":false,"name":"nucleotide-excision repair, preincision complex stabilization","termid":"GO:0006293"}


id: PBO:0052579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinase non-catalytic C-lobe domain containing 1","termid":"PBO:0052579"}


id: PR:000050542
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A GTP-binding protein gtr1 (Schizosaccharomyces pombe) that is non-covalently bound to GDP.","definition_xrefs":["PRO:DAN","PMID:27227887","PomBase:VW","PMID:33534698"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"},{"relation_name":"is_a","term_name":"GTP-binding protein gtr1 (Schizosaccharomyces pombe)","termid":"PR:000050541"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gtr1/GDP+","pombase_gene_id":"SPBC337.13c","synonyms":[{"name":"PomBase_original_PRO_term_name: GTP-binding protein gtr1, GDP-bound form (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-gtr1/GDP+","type":"exact"},{"name":"gtr1/GDP+","type":"exact"},{"name":"Gtr1/GDP+","type":"exact"}],"termid":"PR:000050542"}


id: MONDO:0013572
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary lipodystrophy","termid":"MONDO:0020087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066"],"is_obsolete":false,"name":"Keppen-Lubinsky syndrome","secondary_identifiers":["OMIM:614098","Orphanet:435628","GARD:17716","UMLS:C3279800","MEDGEN:481430"],"synonyms":[{"name":"KEPPEN-Lubinsky syndrome","type":"related"},{"name":"KPLBS","type":"related"},{"name":"Keppen-Lubinsky syndrome","type":"exact"},{"name":"generalised lipodystrophy-progeroid features-severe intellectual disability syndrome","type":"exact"},{"name":"generalized lipodystrophy-progeroid features-severe intellectual disability syndrome","type":"exact"}],"termid":"MONDO:0013572","xrefs":{"Monarch":{"xref_id":"0013572"}}}


id: MONDO:1010781
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Alopecia areata that occurs in pig.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alopecia areata, non-human animal","termid":"MONDO:1010140"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alopecia areata, pig","secondary_identifiers":["OMIA:001702-9823"],"termid":"MONDO:1010781","xrefs":{"Monarch":{"xref_id":"1010781"}}}


id: PBO:0012061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial metallopeptidase predicted to be involved in tRNA threonylcarbamoyladenosine modification Pgp1","termid":"PBO:0012061"}


id: MONDO:0007932
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An age related macular degeneration conferred by variation in the ABCA4 gene on chromosome 1p22.","definition_xrefs":["DOID:0110015","PMID:10396622"],"direct_ancestors":[{"relation_name":"is_a","term_name":"age-related macular degeneration","termid":"MONDO:0005150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"age related macular degeneration 2","secondary_identifiers":["MESH:C562479","MEDGEN:501183","OMIM:153800","UMLS:C3495438"],"synonyms":[{"name":"ARMD2","type":"exact"},{"name":"age related macular degeneration type 2","type":"exact"},{"name":"macular Degeneration, Senile","type":"related"},{"name":"macular Degeneration, age-related, type 2","type":"exact"},{"name":"macular degeneration, age-related, 2","type":"related"},{"name":"maculopathy, age-related, 2","type":"related"}],"termid":"MONDO:0007932","xrefs":{"Monarch":{"xref_id":"0007932"}}}


id: MONDO:0019017
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A syndrome is characterized by bilateral shortening of the fifth fingers and fifth metacarpals. It has been described in several members of one family. Some members of the family also had spherocytosis and insulin resistance. Transmission is autosomal dominant.","definition_xrefs":["Orphanet:66518"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"diabetes mellitus","termid":"MONDO:0005015"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"short fifth metacarpals-insulin resistance syndrome","secondary_identifiers":["UMLS:C4303621","MEDGEN:929290","GARD:18868"],"termid":"MONDO:0019017","xrefs":{"Monarch":{"xref_id":"0019017"}}}


id: PBO:0004926
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetra spanning protein 1, Tts1","termid":"PBO:0004926"}


id: MONDO:0019743
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete nephropathy secondary to a storage or other metabolic disease (obsolete MONDO:0019743)","secondary_identifiers":["Orphanet:93593"],"termid":"MONDO:0019743","xrefs":{"Monarch":{"xref_id":"0019743"}}}


id: MONDO:1040041
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any exudative vitreoretinopathy caused by a variant in the FZD4 gene.","definition_xrefs":["PMID:15035989","PMID:21868098"],"direct_ancestors":[{"relation_name":"is_a","term_name":"exudative vitreoretinopathy","termid":"MONDO:0019516"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0005328"],"is_obsolete":false,"name":"FZD4-related exudative vitreoretinopathy","synonyms":[{"name":"FZD4-related exudative vitreoretinopathy","type":"exact"}],"termid":"MONDO:1040041","xrefs":{"Monarch":{"xref_id":"1040041"}}}


id: MONDO:0019823
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Premature closure of the arterial duct is a rare arterial duct anomaly, defined as a significant constriction or closure of the fetal arterial duct in the absence of structural heart defects with pathognomonic features of increased right ventricular afterload, tricuspid regurgitation and, consequently, right atrial dilation and right ventricular hypertrophy. The severity of symptoms is related to the degree and rate of ductal constriction and ranges from mild postnatal respiratory distress to development of ventricular failure with fetal hydrops and intrauterine death or severe cardiopulmonary compromise in the postnatal period. It may be associated with a prenatal exposure to cyclooxygenase inhibitors or corticosteroids.","definition_xrefs":["Orphanet:95486"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital anomaly of the great arteries","termid":"MONDO:0020292"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"premature closure of the arterial duct","secondary_identifiers":["GARD:19271","MEDGEN:759377","UMLS:C3532264"],"synonyms":[{"name":"premature closure of the patent ductus arteriosus","type":"exact"}],"termid":"MONDO:0019823","xrefs":{"Monarch":{"xref_id":"0019823"}}}


id: MONDO:0957008
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system malformation","termid":"MONDO:0020022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022"],"is_obsolete":false,"name":"hereditary cerebral malformation","secondary_identifiers":["Orphanet:269553","GARD:21004","MEDGEN:1842500","UMLS:C5679762"],"synonyms":[{"name":"genetic cerebral malformation","type":"exact"}],"termid":"MONDO:0957008","xrefs":{"Monarch":{"xref_id":"0957008"}}}


id: PBO:0064886
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 2 regulatory subunit Balpha","termid":"PBO:0064886"}


id: MONDO:0006146
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A hamartoma that is characterized by the presence of chondroid elements.","definition_xrefs":["NCIT:C42589"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"neoplasm","termid":"MONDO:0005070"},{"relation_name":"is_a","term_name":"hamartoma","termid":"MONDO:0006499"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chondroid hamartoma","secondary_identifiers":["MEDGEN:313028","UMLS:C1707390","EFO:1000175"],"termid":"MONDO:0006146","xrefs":{"Monarch":{"xref_id":"0006146"}}}


id: MONDO:0007318
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Alagille (AGS) syndrome is variably characterized by chronic cholestasis due to paucity of intrahepatic bile ducts, peripheral pulmonary artery stenosis, vertebrae segmentation anomalies, characteristic facies, posterior embryotoxon/anterior segment abnormalities, pigmentary retinopathy, and dysplastic kidneys.","definition_xrefs":["Orphanet:52"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"biliary tract disorder","termid":"MONDO:0004868"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005267","MONDO:0004335","MONDO:0005328","MONDO:0002515"],"is_obsolete":false,"name":"Alagille syndrome","secondary_identifiers":["ICD9:759.89","DOID:9245","MESH:D016738","NANDO:1200919","NANDO:1200918","icd11.foundation:1249656206","NCIT:C35139","NORD:748","UMLS:C0085280","MedDRA:10053870","MEDGEN:39014","SCTID:31742004","NANDO:2200931","GARD:804","OMIMPS:118450"],"synonyms":[{"name":"Alagille syndrome","type":"exact"},{"name":"Alagille-Watson syndrome","type":"exact"},{"name":"Arteriohepatic dysplasia","type":"exact"},{"name":"Cardiovertebral syndrome","type":"related"},{"name":"Hepatofacioneurocardiovertebral syndrome","type":"related"},{"name":"Watson Alagille syndrome","type":"related"},{"name":"Watson-Miller syndrome","type":"related"},{"name":"hepatic ductular hypoplasia","type":"related"},{"name":"paucity of interlobular bile ducts","type":"related"},{"name":"syndromic bile duct paucity","type":"exact"}],"termid":"MONDO:0007318","xrefs":{"Monarch":{"xref_id":"0007318"}}}


id: GO:0044416
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:cc"],"gene_count":0,"genotype_count":0,"name":"obsolete induction by symbiont of host defense response (obsolete GO:0044416)","synonyms":[{"name":"activation by symbiont of host defense response","type":"exact"},{"name":"activation of host defense response","type":"exact"},{"name":"induction by organism of defense response of other organism involved in symbiotic interaction","type":"broad"},{"name":"positive regulation by organism of defense response of other organism involved in symbiotic interaction","type":"broad"},{"name":"positive regulation by symbiont of host defense response","type":"related"},{"name":"stimulation by symbiont of host defense response","type":"related"},{"name":"up regulation by symbiont of host defense response","type":"related"},{"name":"up-regulation by symbiont of host defense response","type":"related"},{"name":"upregulation by symbiont of host defense response","type":"related"}],"termid":"GO:0044416"}


id: GO:0052668
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+.","definition_xrefs":["RHEA:51680","PMID:21395888"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prenol kinase activity","termid":"GO:0052673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"CTP:farnesol kinase activity","secondary_identifiers":["GO:0052669","MetaCyc:RXN-11625"],"synonyms":[{"name":"CTP:2-trans,-6-trans-farnesol kinase activity","type":"exact"},{"name":"CTP:2-trans,-6-trans-farnesol phosphotransferase activity","type":"exact"},{"name":"farnesol kinase activity","type":"related"},{"name":"farnesol phosphotransferase activity","type":"exact"},{"name":"trans,trans-farnesol kinase activity","type":"narrow"}],"termid":"GO:0052668"}


id: FYPO:0002359
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in telomeric regions is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H3-K9 methylation during vegetative growth","termid":"FYPO:0003232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001312","FYPO:0000257","FYPO:0001320"],"is_obsolete":false,"name":"normal histone H3-K9 dimethylation at telomere during vegetative growth","synonyms":[{"name":"normal histone H3-K9 dimethylation at telomere during mitotic cell cycle","type":"related"},{"name":"normal histone H3K9me2 at telomere during vegetative growth","type":"exact"},{"name":"normal telomeric histone H3-K9 dimethylation during vegetative growth","type":"exact"}],"termid":"FYPO:0002359"}


id: MONDO:0013689
data:
  {"annotated_genes":["SJAG_04950"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85393],"is_not":false,"summary":null,"term":"MONDO:0013689"}]},"cv_name":"mondo","definition":"Any 46 XX gonadal dysgenesis in which the cause of the disease is a mutation in the PSMC3IP gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"46 XX gonadal dysgenesis","termid":"MONDO:0009299"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04950":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"ovarian dysgenesis 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:18041","MEDGEN:482101","DOID:0080495","OMIM:614324","UMLS:C3280471"],"synonyms":[{"name":"46 XX gonadal dysgenesis caused by mutation in PSMC3IP","type":"exact"},{"name":"ODG3","type":"related"},{"name":"PSMC3IP 46 XX gonadal dysgenesis","type":"exact"},{"name":"ovarian dysgenesis 3","type":"exact"},{"name":"ovarian dysgenesis type 3","type":"exact"}],"termid":"MONDO:0013689","terms_by_termid":{"MONDO:0013689":null},"xrefs":{"Monarch":{"xref_id":"0013689"}}}


id: GO:0106231
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD+ = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.","definition_xrefs":["GOC:sp","PMID:30026585","RHEA:23500"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NAD-dependent protein lysine deacylase activity","termid":"GO:0141218"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0019213"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140096","GO:0003674","GO:0019213","GO:0003824"],"is_obsolete":false,"name":"NAD-dependent protein-lysine depropionylase activity","termid":"GO:0106231"}


id: GO:0098787
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.","definition_xrefs":["GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete mRNA cleavage involved in mRNA processing (obsolete GO:0098787)","termid":"GO:0098787"}


id: MOD:01266
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Chemical derivative -","definition_xrefs":["PubMed:15549660","Unimod:271#C"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleophilic addition to cytopiloyne+H2O","termid":"MOD:00591"},{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"nucleophilic addition to cytopiloyne+H2O - site C","synonyms":[{"name":"Cytopiloyne+water","type":"related"},{"name":"nucleophilic addition to cytopiloyne+H2O","type":"related"}],"termid":"MOD:01266"}


id: MONDO:0800374
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"catecholaminergic polymorphic ventricular tachycardia","termid":"MONDO:0017990"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"ventricular tachycardia, catecholaminergic polymorphic 6","secondary_identifiers":["UMLS:C5394069","MEDGEN:1712279"],"synonyms":[{"name":"CPVT6","type":"exact"}],"termid":"MONDO:0800374","xrefs":{"Monarch":{"xref_id":"0800374"}}}


id: MONDO:0008995
data:
  {"annotated_genes":["SJAG_02289"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85986],"is_not":false,"summary":null,"term":"MONDO:0008995"}]},"cv_name":"mondo","definition":"Yunis-Varon syndrome is a rare condition that affects many different parts of the body. Signs and symptoms are generally present from birth and may include underdeveloped or absent collarbones (clavicles); large fontanelles; characteristic facial features; hypotonia (reduced muscle tone) and/or abnormalities of the fingers and toes. Affected people may also experience feeding difficulties, breathing problems, brain malformations, heart defects, skeletal abnormalities, developmental delay, and/or intellectual disability. Yunis-Varon syndrome is caused by changes (mutations) in the FIG4 gene and isinherited in an autosomal recessive manner. Treatment is based on the signs and symptoms present in each person.","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02289":null},"genotype_count":0,"is_obsolete":false,"name":"Yunis-Varon syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1696991249","MEDGEN:341818","MESH:C536719","GARD:331","UMLS:C1857663","DOID:0060589","NORD:1875","OMIM:216340","Orphanet:3472"],"synonyms":[{"name":"YVS","type":"related"},{"name":"Yunis Varon Syndrome","type":"exact"},{"name":"Yunis Varon syndrome","type":"exact"},{"name":"Yunis-Varon syndrome","type":"exact"},{"name":"Yunis-Varón syndrome","type":"exact"},{"name":"cleidocranial dysplasia with micrognathia, absent thumbs, and distal Aphalangia","type":"related"},{"name":"cleidocranial dysplasia with micrognathia, absent thumbs, and distal aphalangia","type":"exact"},{"name":"cleidocranial dysplasia-micrognathia-absent thumbs syndrome","type":"exact"}],"termid":"MONDO:0008995","terms_by_termid":{"MONDO:0008995":null},"xrefs":{"Monarch":{"xref_id":"0008995"}}}


id: MONDO:0009329
data:
  {"annotated_genes":["SJAG_00169"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86824],"is_not":false,"summary":null,"term":"MONDO:0009329"}]},"cv_name":"mondo","definition":"A rare form of pulmonary arterial hypertension (PAH) characterized by a capillary infiltration of the pulmonary interstitium, bronchioles and pleura leading to elevated pulmonary arterial resistance and right heart failure. PCH is potentially fatal.","definition_xrefs":["Orphanet:199241"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"pulmonary veno-occlusive disease and/or pulmonary capillary haemangiomatosis","termid":"MONDO:0018554"},{"relation_name":"is_a","term_name":"pulmonary venoocclusive disease","termid":"MONDO:0009937"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00169":null},"genotype_count":0,"is_obsolete":false,"name":"pulmonary venoocclusive disease 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:90956","OMIM:234810","DOID:0081269","GARD:15027","UMLS:C0340848","MESH:C535861","ICD9:416.8","SCTID:233949008"],"synonyms":[{"name":"PVOD2","type":"related"},{"name":"familial pulmonary capillary hemangiomatosis","type":"related"},{"name":"hemangiomatosis, familial pulmonary capillary","type":"related"},{"name":"pulmonary capillary hemangiomatosis","type":"broad"},{"name":"pulmonary venoocclusive disease 2, autosomal recessive","type":"related"}],"termid":"MONDO:0009329","terms_by_termid":{"MONDO:0009329":null},"xrefs":{"Monarch":{"xref_id":"0009329"}}}


id: PBO:0028271
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_malate_dehydrogenase_(decarboxylating)_(NAD+)_activity","termid":"PBO:0028271"}


id: PBO:0045130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication helicase/nuclease 2","termid":"PBO:0045130"}


id: GO:0003382
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.","definition_xrefs":["GOC:tb","GOC:ascb_2009","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell morphogenesis","termid":"GO:0000902"},{"relation_name":"part_of","term_name":"epithelial cell development","termid":"GO:0002064"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"epithelial cell morphogenesis","termid":"GO:0003382"}


id: MONDO:0019513
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete esophageal malformation (obsolete MONDO:0019513)","secondary_identifiers":["icd11.foundation:1999264345","Orphanet:88993"],"termid":"MONDO:0019513","xrefs":{"Monarch":{"xref_id":"0019513"}}}


id: PR:O74519
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- naa50 gene.","definition_xrefs":["UniProtKB:O74519","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized N-acetyltransferase C663.13c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC663.13c","synonyms":[{"name":"Spom972h-naa50","type":"exact"}],"termid":"PR:O74519"}


id: PBO:0082617
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of 90S preribosomes; involved in early cleavages of the 35S pre-rRNA and in production of the 40S ribosomal subunit","termid":"PBO:0082617"}


id: PBO:0030202
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-viable_elongated_multiseptate_vegetative_cell","termid":"PBO:0030202"}


id: GO:1900008
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.","definition_xrefs":["GOC:TermGenie","PMID:15020466"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging (obsolete GO:1900008)","synonyms":[{"name":"down regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing","type":"related"},{"name":"down regulation of extrachromosomal rDNA circle accumulation during replicative cell aging","type":"related"},{"name":"down regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging","type":"related"},{"name":"down regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging","type":"related"},{"name":"negative regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing","type":"related"},{"name":"negative regulation of extrachromosomal rDNA circle accumulation during replicative cell aging","type":"related"},{"name":"negative regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging","type":"related"}],"termid":"GO:1900008"}


id: GO:1903894
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.","definition_xrefs":["GO_REF:0000058","GOC:PARL","GOC:TermGenie","PMID:22013210","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of endoplasmic reticulum unfolded protein response","termid":"GO:1900101"},{"relation_name":"regulates","term_name":"IRE1-mediated unfolded protein response","termid":"GO:0036498"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of IRE1-mediated unfolded protein response","synonyms":[{"name":"regulation of ERN1-mediated unfolded protein response","type":"related"},{"name":"regulation of IRE1 branch of UPR","type":"exact"},{"name":"regulation of IRE1 signal transduction pathway","type":"broad"},{"name":"regulation of IRE1 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"regulation of IRE1alpha unfolded protein response","type":"narrow"},{"name":"regulation of IRE1p unfolded protein response","type":"narrow"},{"name":"regulation of UPR signaling by IRE1 stress sensor","type":"exact"},{"name":"regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling","type":"exact"},{"name":"regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction","type":"related"}],"termid":"GO:1903894"}


id: PBO:0116793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COL15A1 antisense RNA 1","termid":"PBO:0116793"}


id: GO:0033621
data:
  {"annotated_genes":["SJAG_04601","SJAG_03883","SJAG_04006","SJAG_01867","SJAG_01540","SJAG_00456","SJAG_02723","SJAG_02720","SJAG_00452","SJAG_01412","SJAG_04768","SJAG_03454","SJAG_03745","SJAG_02382","SJAG_02622"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[87240,90547,90623,91620,92002,96499,98879,104089,107255,109040,109059,111098,117923],"is_not":false,"summary":null,"term":"GO:0033621"},{"annotations":[89533],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:0120271"},{"annotations":[106455],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0120272"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.","definition_xrefs":["PMID:16823445"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear mRNA surveillance","termid":"GO:0071028"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00452":null,"SJAG_00456":null,"SJAG_01412":null,"SJAG_01540":null,"SJAG_01867":null,"SJAG_02382":null,"SJAG_02622":null,"SJAG_02720":null,"SJAG_02723":null,"SJAG_03454":null,"SJAG_03745":null,"SJAG_03883":null,"SJAG_04006":null,"SJAG_04601":null,"SJAG_04768":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016071"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467","GO:0016071"],"is_obsolete":false,"name":"nuclear mRNA surveillance of meiosis-specific transcripts","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"degradation of meiosis-specific transcripts","type":"exact"},{"name":"mRNA breakdown, meiosis-specific transcripts","type":"exact"},{"name":"mRNA catabolism, meiosis-specific transcripts","type":"exact"},{"name":"mRNA degradation, meiosis-specific transcripts","type":"exact"},{"name":"nuclear mRNA catabolic process, meiosis-specific transcripts","type":"exact"},{"name":"nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts","type":"exact"}],"termid":"GO:0033621","terms_by_termid":{"GO:0033621":null,"GO:0120271":null,"GO:0120272":null}}


id: GO:0071010
data:
  {"annotated_genes":["SJAG_04911","SJAG_00147","SJAG_00322","SJAG_00058","SJAG_03210","SJAG_00474","SJAG_00498","SJAG_03983","SJAG_04214","SJAG_04318","SJAG_01301","SJAG_00504","SJAG_00577","SJAG_05009","SJAG_05240","SJAG_03469","SJAG_00859","SJAG_00911","SJAG_01870","SJAG_03547","SJAG_02844","SJAG_00225","SJAG_00809","SJAG_03995","SJAG_01654","SJAG_02558","SJAG_02279","SJAG_04163","SJAG_01008","SJAG_02304","SJAG_02185","SJAG_00249"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[88263,101528,108568,109304,113081,78645,96097,110438,95361,72006,72815,102333,109854,106203,73766,101034,94937,105314,69703,73578,118527,93134,79299,71831,106741,105674,112453,113652,70110,75501,112164,76440],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071004"}]},"cv_name":"cellular_component","definition":"A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.","definition_xrefs":["PMID:19239890","PMID:17332742","GOC:krc","GOC:ab","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spliceosomal complex","termid":"GO:0005681"}],"gene_count":32,"genes_by_uniquename":{"SJAG_00058":null,"SJAG_00147":null,"SJAG_00225":null,"SJAG_00249":null,"SJAG_00322":null,"SJAG_00474":null,"SJAG_00498":null,"SJAG_00504":null,"SJAG_00577":null,"SJAG_00809":null,"SJAG_00859":null,"SJAG_00911":null,"SJAG_01008":null,"SJAG_01301":null,"SJAG_01654":null,"SJAG_01870":null,"SJAG_02185":null,"SJAG_02279":null,"SJAG_02304":null,"SJAG_02558":null,"SJAG_02844":null,"SJAG_03210":null,"SJAG_03469":null,"SJAG_03547":null,"SJAG_03983":null,"SJAG_03995":null,"SJAG_04163":null,"SJAG_04214":null,"SJAG_04318":null,"SJAG_04911":null,"SJAG_05009":null,"SJAG_05240":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005634"],"is_obsolete":false,"name":"prespliceosome","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"mammalian spliceosomal complex A","type":"narrow"},{"name":"prespliceosomal complex","type":"exact"},{"name":"yeast spliceosomal complex B","type":"narrow"}],"termid":"GO:0071010","terms_by_termid":{"GO:0071004":null}}


id: PR:Q9UT14
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC9E9.17c gene.","definition_xrefs":["UniProtKB:Q9UT14","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C9E9.17c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC9E9.17c","synonyms":[{"name":"Spom972h-SPAC9E9.17c","type":"exact"}],"termid":"PR:Q9UT14"}


id: MONDO:0019483
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Methotrexate-associated lymphoproliferative disorders are rare immunodeficiency-associated lymphoproliferative diseases characterized by lymphoid proliferation or lymphomas (large B-cell lymphoma, T-cell lymphoma, Hodgkin lymphoma, reactive lymphadenitis and a polymorphic post-transplant lymphoproliferative disorder) that develop in patients with different autoimmune diseases treated with methotrexate. Swelling is the predominant manifestation of the disease and regression after methotrexate withdrawal is observed in a significant proportion of patients.","definition_xrefs":["Orphanet:86904"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lymphoma","termid":"MONDO:0005062"},{"relation_name":"is_a","term_name":"immunodeficiency-associated lymphoproliferative disease","termid":"MONDO:0020083"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"methotrexate-associated lymphoproliferative disorders","secondary_identifiers":["icd11.foundation:1520483526","MEDGEN:233702","NCIT:C7184","GARD:19083","UMLS:C1334749","DOID:5821"],"synonyms":[{"name":"MTX-LPD","type":"exact"},{"name":"MTX-associated lymphoproliferative disorders","type":"exact"},{"name":"methotrexate-associated lymphoproliferation","type":"exact"},{"name":"methotrexate-associated lymphoproliferative disorder","type":"exact"}],"termid":"MONDO:0019483","xrefs":{"Monarch":{"xref_id":"0019483"}}}


id: MONDO:0016968
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial trisomy/tetrasomy of chromosome 18","termid":"MONDO:0016936"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial trisomy of the long arm of chromosome 18","secondary_identifiers":["MESH:C538308","UMLS:C0809935","Orphanet:262977","GARD:20888","MEDGEN:167200"],"synonyms":[{"name":"18q duplication","type":"related"},{"name":"18q partial trisomy","type":"related"},{"name":"18q trisomy","type":"related"},{"name":"Duplication 18q","type":"related"},{"name":"chromosome 18q duplication","type":"related"},{"name":"partial duplication of chromosome 18q","type":"exact"},{"name":"partial duplication of the long arm of chromosome 18","type":"exact"},{"name":"partial trisomy of chromosome 18q","type":"exact"},{"name":"partial trisomy of the long arm of chromosome type 18","type":"exact"},{"name":"trisomy 18q","type":"related"}],"termid":"MONDO:0016968","xrefs":{"Monarch":{"xref_id":"0016968"}}}


id: PBO:0082217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha 6 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress","termid":"PBO:0082217"}


id: PBO:0085486
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Processivity factor; required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis; contains a conserved DOC1 homology domain","termid":"PBO:0085486"}


id: MONDO:0018430
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, hereditary, cerebral malformation with epilepsy syndrome characterized by severe global developmental delay with no ability to walk and no verbal language, intractable epilepsy, partial agenesis of the corpus callosum and cerebellar vermis hypoplasia with posterior fossa cysts.","definition_xrefs":["Orphanet:401959"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system malformation","termid":"MONDO:0020022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022"],"is_obsolete":false,"name":"partial corpus callosum agenesis-cerebellar vermis hypoplasia with posterior fossa cysts syndrome","secondary_identifiers":["GARD:21707","UMLS:C4750913","MEDGEN:1660429"],"termid":"MONDO:0018430","xrefs":{"Monarch":{"xref_id":"0018430"}}}


id: PBO:0066547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of G protein signaling 10","termid":"PBO:0066547"}


id: MONDO:0014042
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any left ventricular noncompaction in which the cause of the disease is a mutation in the MIB1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"left ventricular noncompaction","termid":"MONDO:0018901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"left ventricular noncompaction 7","secondary_identifiers":["UMLS:C3554496","NCIT:C157266","GARD:15906","MEDGEN:767410","OMIM:615092"],"synonyms":[{"name":"LVNC7","type":"related"},{"name":"MIB1 left ventricular noncompaction","type":"exact"},{"name":"left ventricular noncompaction 7","type":"exact"},{"name":"left ventricular noncompaction caused by mutation in MIB1","type":"exact"},{"name":"left ventricular noncompaction type 7","type":"exact"}],"termid":"MONDO:0014042","xrefs":{"Monarch":{"xref_id":"0014042"}}}


id: GO:2000742
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of anterior head development.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of developmental process","termid":"GO:0050793"},{"relation_name":"regulates","term_name":"anterior head development","termid":"GO:0097065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of anterior head development","termid":"GO:2000742"}


id: GO:0099610
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.","definition_xrefs":["ISBN:978-0071390118","PMID:19439602"],"direct_ancestors":[{"relation_name":"is_a","term_name":"action potential","termid":"GO:0001508"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"action potential initiation","synonyms":[{"name":"action potential firing","type":"exact"},{"name":"action potential triggering","type":"exact"}],"termid":"GO:0099610"}


id: MONDO:0002642
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm involving a trochlear nerve.","definition_xrefs":["MONDO:patterns/neoplasm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve neoplasm","termid":"MONDO:0002633"},{"relation_name":"is_a","term_name":"trochlear nerve disorder","termid":"MONDO:0007002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trochlear nerve neoplasm","secondary_identifiers":["UMLS:C1263896","ICD9:239.7","NCIT:C5825","DOID:3421","MEDGEN:226811","SCTID:126970001"],"synonyms":[{"name":"IVth cranial nerve neoplasms","type":"exact"},{"name":"IVth cranial nerve tumors","type":"exact"},{"name":"IVth cranial nerve tumours","type":"exact"},{"name":"fourth cranial nerve neoplasm","type":"exact"},{"name":"fourth cranial nerve neoplasms","type":"exact"},{"name":"fourth cranial nerve tumor","type":"exact"},{"name":"fourth cranial nerve tumors","type":"exact"},{"name":"fourth cranial nerve tumour","type":"exact"},{"name":"fourth cranial nerve tumours","type":"exact"},{"name":"neoplasm of fourth cranial nerve","type":"exact"},{"name":"neoplasm of the fourth cranial nerve","type":"exact"},{"name":"neoplasm of the trochlear nerve","type":"exact"},{"name":"neoplasm of trochlear nerve","type":"exact"},{"name":"trochlear nerve neoplasm (disease)","type":"exact"},{"name":"trochlear nerve neoplasms","type":"exact"},{"name":"trochlear nerve tumor","type":"exact"},{"name":"trochlear nerve tumors","type":"exact"},{"name":"trochlear nerve tumour","type":"exact"},{"name":"trochlear nerve tumours","type":"exact"},{"name":"tumor of fourth cranial nerve","type":"exact"},{"name":"tumor of the fourth cranial nerve","type":"exact"},{"name":"tumor of the trochlear nerve","type":"exact"},{"name":"tumor of trochlear nerve","type":"exact"},{"name":"tumour of fourth cranial nerve","type":"exact"},{"name":"tumour of the fourth cranial nerve","type":"exact"},{"name":"tumour of the trochlear nerve","type":"exact"},{"name":"tumour of trochlear nerve","type":"exact"}],"termid":"MONDO:0002642","xrefs":{"Monarch":{"xref_id":"0002642"}}}


id: PBO:0049654
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H4 clustered histone 8","termid":"PBO:0049654"}


id: PR:O14243
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A sorting nexin-30 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01154","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin-4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC6F6.12","secondary_identifiers":["UniProtKB:O14243"],"synonyms":[{"name":"Spom972h-SNX30","type":"exact"},{"name":"autophagy-related protein 24 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14243"}


id: MONDO:1011875
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progressive ataxia with head tremor and seizures, non-human animal","secondary_identifiers":["OMIA:001363"],"termid":"MONDO:1011875","xrefs":{"Monarch":{"xref_id":"1011875"}}}


id: MONDO:0022739
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Christian Demyer Franken syndrome","termid":"MONDO:0022739","xrefs":{"Monarch":{"xref_id":"0022739"}}}


id: PBO:0087728
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate","termid":"PBO:0087728"}


id: PBO:0059870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotubularin related protein 8","termid":"PBO:0059870"}


id: PBO:0040400
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase H+ transporting V1 subunit G1 pseudogene 1","termid":"PBO:0040400"}


id: GO:0070050
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular homeostasis","termid":"GO:0019725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neuron cellular homeostasis","synonyms":[{"name":"neuron maintenance","type":"exact"}],"termid":"GO:0070050"}


id: PBO:0080519
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WASP family member 5, pseudogene","termid":"PBO:0080519"}


id: PBO:0053222
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat LGI family member 2","termid":"PBO:0053222"}


id: PBO:0084662
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial 3-hydroxyacyl-thioester dehydratase; involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology","termid":"PBO:0084662"}


id: PBO:0045291
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynamin 1 pseudogene 43","termid":"PBO:0045291"}


id: MOD:01605
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-glutamic acid residue to 5-glutamyl 2-aminoadipic acid.","definition_xrefs":["PubMed:19620981","ChEBI:78503","RESID:AA0502"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amidated residue","termid":"MOD:00674"},{"relation_name":"is_a","term_name":"modified L-glutamic acid residue","termid":"MOD:00906"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5-glutamyl 2-aminoadipic acid","synonyms":[{"name":"(2S)-2-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanedioic acid","type":"exact"},{"name":"5-glutamyl 2-aminoadipic acid","type":"exact"},{"name":"MOD_RES 5-glutamyl 2-aminoadipic acid","type":"exact"},{"name":"N2-(gamma-glutamyl)-2-aminoadipic acid","type":"exact"},{"name":"N2-(isoglutamyl)-2-aminoadipic acid","type":"exact"}],"termid":"MOD:01605"}


id: PBO:0040776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bestrophin 2","termid":"PBO:0040776"}


id: GO:0097226
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.","definition_xrefs":["PMID:32791035","GOC:cjm","MP:0009832"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"sperm midpiece","termid":"GO:0097225"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"sperm mitochondrial sheath","termid":"GO:0097226"}


id: PBO:0075676
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spexin hormone","termid":"PBO:0075676"}


id: GO:1900825
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.","definition_xrefs":["GOC:TermGenie","GOC:BHF","GOC:mtg_cardiac_conduct_nov11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of membrane depolarization during action potential","termid":"GO:0098902"},{"relation_name":"regulates","term_name":"membrane depolarization during cardiac muscle cell action potential","termid":"GO:0086012"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of membrane depolarization during cardiac muscle cell action potential","termid":"GO:1900825"}


id: PBO:0083758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress","termid":"PBO:0083758"}


id: MONDO:0008168
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm arising from soft tissue of the ovary. It is characterized by the presence of spindle-shaped fibroblasts.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovarian benign neoplasm","termid":"MONDO:0000646"},{"relation_name":"is_a","term_name":"fibroma","termid":"MONDO:0005167"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovarian fibroma","secondary_identifiers":["SCTID:254865006","UMLS:C0149951","HP:0010618","MESH:C562391","GARD:21375","MedDRA:10064257","OMIM:166970","icd11.foundation:871413134","MEDGEN:57706","NCIT:C3498","Orphanet:314473"],"synonyms":[{"name":"fibroma of ovary","type":"exact"},{"name":"fibroma of the ovary","type":"exact"},{"name":"ovarian fibroma","type":"exact"},{"name":"ovarian fibroma (disease)","type":"exact"},{"name":"ovarian fibromata","type":"related"}],"termid":"MONDO:0008168","xrefs":{"Monarch":{"xref_id":"0008168"}}}


id: PBO:0090910
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"D-serine ammonia-lyase activity","termid":"PBO:0090910"}


id: PBO:0085653
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in mitochondrial fission and peroxisome abundance; may have a distinct role in tethering protein aggregates to mitochondria in order to retain them in the mother cell; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation","termid":"PBO:0085653"}


id: GO:0018268
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.","definition_xrefs":["RESID:AA0161"],"gene_count":0,"genotype_count":0,"name":"obsolete GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine (obsolete GO:0018268)","termid":"GO:0018268"}


id: PR:Q9UUA2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ATP-dependent DNA helicase PIF1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR23274:SF0","PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent DNA helicase pfh1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC887.14c","secondary_identifiers":["UniProtKB:Q9UUA2"],"synonyms":[{"name":"DNA repair and recombination helicase pfh1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"PIF1 helicase homolog (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RRM3/PIF1 homolog 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPBC887.14c","type":"related"},{"name":"Spom972h-PIF1","type":"exact"},{"name":"pif1","type":"related"},{"name":"rph1","type":"related"}],"termid":"PR:Q9UUA2"}


id: PBO:0072396
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S27 pseudogene 1","termid":"PBO:0072396"}


id: GO:1901081
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of relaxation of muscle","termid":"GO:1901078"},{"relation_name":"is_a","term_name":"regulation of relaxation of smooth muscle","termid":"GO:1901080"},{"relation_name":"negatively_regulates","term_name":"relaxation of smooth muscle","termid":"GO:0044557"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of relaxation of smooth muscle","synonyms":[{"name":"down regulation of relaxation of smooth muscle","type":"exact"},{"name":"down regulation of smooth muscle relaxation","type":"exact"},{"name":"down-regulation of relaxation of smooth muscle","type":"exact"},{"name":"down-regulation of smooth muscle relaxation","type":"exact"},{"name":"downregulation of relaxation of smooth muscle","type":"exact"},{"name":"downregulation of smooth muscle relaxation","type":"exact"},{"name":"inhibition of relaxation of smooth muscle","type":"narrow"},{"name":"inhibition of smooth muscle relaxation","type":"exact"},{"name":"negative regulation of smooth muscle relaxation","type":"exact"}],"termid":"GO:1901081"}


id: MONDO:0015911
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Hemolytic anemia, the cause of which is not present at birth.","definition_xrefs":["NCIT:C34377"],"gene_count":0,"genotype_count":0,"name":"obsolete rare acquired hemolytic anemia (obsolete MONDO:0015911)","secondary_identifiers":["Orphanet:182047","SCTID:4854004","ICD10CM:D59.3","ICD10CM:D59.0"],"synonyms":[{"name":"Acquired hemolytic Anemia","type":"exact"}],"termid":"MONDO:0015911","xrefs":{"Monarch":{"xref_id":"0015911"}}}


id: MONDO:0012947
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant non-syndromic intellectual disability in which the cause of the disease is a mutation in the KIRREL3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intellectual disability, autosomal dominant","termid":"MONDO:0100172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"intellectual disability, autosomal dominant 4","secondary_identifiers":["GARD:16455","OMIM:612581","UMLS:C2675487","DOID:0070034","MEDGEN:393397","MESH:C567240"],"synonyms":[{"name":"KIRREL3 autosomal dominant non-syndromic intellectual disability","type":"exact"},{"name":"MRD4","type":"exact"},{"name":"autosomal dominant intellectual disability 4","type":"exact"},{"name":"autosomal dominant mental retardation 4","type":"exact"},{"name":"autosomal dominant non-syndromic intellectual disability 4","type":"related"},{"name":"autosomal dominant non-syndromic intellectual disability caused by mutation in KIRREL3","type":"exact"},{"name":"intellectual disability, autosomal dominant 4","type":"exact"},{"name":"intellectual disability, autosomal dominant type 4","type":"exact"},{"name":"mental retardation, autosomal dominant 4","type":"related"},{"name":"mental retardation, autosomal dominant type 4","type":"exact"}],"termid":"MONDO:0012947","xrefs":{"Monarch":{"xref_id":"0012947"}}}


id: PR:Q09717
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A ran-specific GTPase-activating protein that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ran-specific GTPase-activating protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1773.07c","secondary_identifiers":["UniProtKB:Q09717"],"synonyms":[{"name":"RANBP1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPBC1773.07c","type":"related"},{"name":"Spom972h-RANBP1","type":"exact"},{"name":"ran-binding protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"spi1-binding protein (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"yrb1","type":"related"}],"termid":"PR:Q09717"}


id: PBO:0071014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 16","termid":"PBO:0071014"}


id: MONDO:0859173
data:
  {"annotated_genes":["SJAG_03081"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86114],"is_not":false,"summary":null,"term":"MONDO:0859173"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial sick sinus syndrome","termid":"MONDO:0012061"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03081":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"sick sinus syndrome 4","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5561949","OMIM:619464","MEDGEN:1794159"],"termid":"MONDO:0859173","terms_by_termid":{"MONDO:0859173":null},"xrefs":{"Monarch":{"xref_id":"0859173"}}}


id: PBO:0003127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alcohol dehydrogenase (predicted)","termid":"PBO:0003127"}


id: CHEBI:49786
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nickel(2+)","termid":"CHEBI:49786"}


id: GO:0060235
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.","definition_xrefs":["GOC:dph","ISBN:0878932437"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental induction","termid":"GO:0031128"},{"relation_name":"part_of","term_name":"lens morphogenesis in camera-type eye","termid":"GO:0002089"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lens induction in camera-type eye","termid":"GO:0060235"}


id: MONDO:0000007
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete atypical Mycobacteriosis, familial (obsolete MONDO:0000007)","termid":"MONDO:0000007","xrefs":{"Monarch":{"xref_id":"0000007"}}}


id: PBO:0091215
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pdc2-Repressed lncRNA","termid":"PBO:0091215"}


id: PBO:0080327
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 91 pseudogene","termid":"PBO:0080327"}


id: RO:0002285
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else","direct_ancestors":[{"relation_name":"is_a","term_name":"developmentally_preceded_by","termid":"RO:0002258"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"developmentally_replaces","termid":"RO:0002285"}


id: GO:0070759
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cytokine-mediated signaling pathway","termid":"GO:0001960"},{"relation_name":"is_a","term_name":"regulation of interleukin-35-mediated signaling pathway","termid":"GO:0070758"},{"relation_name":"negatively_regulates","term_name":"interleukin-35-mediated signaling pathway","termid":"GO:0070757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of interleukin-35-mediated signaling pathway","synonyms":[{"name":"negative regulation of IL-35-mediated signaling pathway","type":"exact"},{"name":"negative regulation of interleukin-35-mediated signalling pathway","type":"exact"}],"termid":"GO:0070759"}


id: PBO:0091201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Asn","termid":"PBO:0091201"}


id: GO:1902815
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of N,N'-diacetylchitobiose into a cell or organelle.","definition_xrefs":["GOC:am","PMID:9405618","GOC:TermGenie","GO_REF:0000073"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate derivative transport","termid":"GO:1901264"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"N,N'-diacetylchitobiose import","termid":"GO:1902815"}


id: GO:0030598
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.","definition_xrefs":["EC:3.2.2.22","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA glycosylase activity","termid":"GO:0030597"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a rRNA","termid":"GO:0140102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140098","GO:0016787","GO:0003674","GO:0016798","GO:0003824"],"is_obsolete":false,"name":"rRNA N-glycosylase activity","secondary_identifiers":["MetaCyc:3.2.2.22-RXN"],"synonyms":[{"name":"RNA N-glycosidase activity","type":"related"},{"name":"gelonin","type":"related"},{"name":"mirabilis antiviral protein","type":"related"},{"name":"momorcochin-S","type":"related"},{"name":"nigrin b","type":"related"},{"name":"rRNA N-glycohydrolase activity","type":"related"},{"name":"rRNA N-glycosidase activity","type":"exact"},{"name":"ribosomal ribonucleate N-glycosidase activity","type":"related"},{"name":"ricin","type":"related"},{"name":"saporins","type":"related"}],"termid":"GO:0030598"}


id: MONDO:0012082
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"excluded_subClassOf","term_name":"Asperger syndrome","termid":"MONDO:0005259"},{"relation_name":"is_a","term_name":"Asperger syndrome, susceptibility to","termid":"MONDO:0100440"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"asperger syndrome, susceptibility to, 1","secondary_identifiers":["MEDGEN:325218","OMIM:608638","UMLS:C1837646"],"synonyms":[{"name":"ASPERGER syndrome, susceptibility to, 1","type":"related"},{"name":"ASPG1","type":"exact"},{"name":"Asperger syndrome susceptibility 1, Isolated cases","type":"exact"}],"termid":"MONDO:0012082","xrefs":{"Monarch":{"xref_id":"0012082"}}}


id: PBO:0048106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"far upstream element binding protein 1","termid":"PBO:0048106"}


id: PBO:0003827
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AAA family ATPase Rix7 (predicted)","termid":"PBO:0003827"}


id: PBO:0055889
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 8 VRAC subunit E","termid":"PBO:0055889"}


id: PBO:0052439
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin light chain 4","termid":"PBO:0052439"}


id: PBO:0050160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 3 pseudogene 16","termid":"PBO:0050160"}


id: MONDO:0004044
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign epithelial neoplasm that produces visible warty projections from the epithelial surface of the ureter.","definition_xrefs":["NCIT:C6160"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ureter benign neoplasm","termid":"MONDO:0001398"},{"relation_name":"is_a","term_name":"urothelial papilloma","termid":"MONDO:0004041"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ureter urothelial papilloma","secondary_identifiers":["DOID:6936","MEDGEN:275548","UMLS:C1519823"],"synonyms":[{"name":"ureter urothelial papilloma","type":"exact"}],"termid":"MONDO:0004044","xrefs":{"Monarch":{"xref_id":"0004044"}}}


id: PBO:0061570
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-terminal glutamine amidase 1","termid":"PBO:0061570"}


id: PBO:0086452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative membrane glycoprotein; has strong similarity to Vth2p and Pep1p/Vps10p; may be involved in vacuolar protein sorting","termid":"PBO:0086452"}


id: GO:0080129
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.","definition_xrefs":["PMID:17971041","PMID:12401807"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteasome assembly","termid":"GO:0043248"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0065003"],"is_obsolete":false,"name":"proteasome core complex assembly","synonyms":[{"name":"20S proteasome assembly","type":"exact"}],"termid":"GO:0080129"}


id: GO:0036405
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the cell outer membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.","definition_xrefs":["GOC:dos","GOC:md"],"gene_count":0,"genotype_count":0,"name":"obsolete anchored component of cell outer membrane (obsolete GO:0036405)","synonyms":[{"name":"anchored to cell outer membrane","type":"narrow"}],"termid":"GO:0036405"}


id: FYPO:0006129
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype in which the occurrence of nuclear migration involved in conjugation with cellular fusion is decreased.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete decreased nuclear migration during mating (obsolete FYPO:0006129)","synonyms":[{"name":"decreased nuclear migration involved in conjugation with cellular fusion","type":"exact"},{"name":"decreased nuclear movement during mating","type":"exact"},{"name":"decreased nuclear movement during shmooing","type":"related"},{"name":"reduced nuclear migration during mating","type":"exact"}],"termid":"FYPO:0006129"}


id: PBO:0069278
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 534, pseudogene","termid":"PBO:0069278"}


id: PBO:0001394
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gene merge","termid":"PBO:0001394"}


id: MONDO:0013978
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the PNPT1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 70","secondary_identifiers":["UMLS:C1824925","GARD:22646","OMIM:614934","MEDGEN:760477","DOID:0110521"],"synonyms":[{"name":"DFNB70","type":"narrow"},{"name":"PNPT1 autosomal recessive nonsyndromic deafness","type":"narrow"},{"name":"autosomal recessive deafness 70","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 70","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness caused by mutation in PNPT1","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 70","type":"narrow"},{"name":"deafness, autosomal recessive 70","type":"narrow"},{"name":"deafness, autosomal recessive type 70","type":"narrow"}],"termid":"MONDO:0013978","xrefs":{"Monarch":{"xref_id":"0013978"}}}


id: PBO:0038993
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenylosuccinate synthase 2","termid":"PBO:0038993"}


id: MONDO:0015877
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete malformative syndrome with dentinogenesis imperfecta (obsolete MONDO:0015877)","secondary_identifiers":["Orphanet:180766"],"termid":"MONDO:0015877","xrefs":{"Monarch":{"xref_id":"0015877"}}}


id: SO:0001377
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"3_methylpseudouridine is a modified uridine base feature.","direct_ancestors":[{"relation_name":"is_a","term_name":"modified_uridine","termid":"SO:0001277"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"three_methylpseudouridine","secondary_identifiers":["RNAMOD:094"],"synonyms":[{"name":"3-methylpseudouridine","type":"exact"},{"name":"m3Y","type":"exact"},{"name":"three methylpseudouridine","type":"exact"}],"termid":"SO:0001377"}


id: MONDO:0024338
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"glandular cell neoplasm","termid":"MONDO:0024276"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mucinous neoplasm","secondary_identifiers":["MEDGEN:235339","NCIT:C7070","UMLS:C1334811"],"synonyms":[{"name":"mucinous neoplasm","type":"exact"},{"name":"mucinous tumor","type":"exact"},{"name":"mucinous tumour","type":"exact"}],"termid":"MONDO:0024338","xrefs":{"Monarch":{"xref_id":"0024338"}}}


id: PBO:0056440
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MARK2 pseudogene 13","termid":"PBO:0056440"}


id: PBO:0079404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tubulin beta 7 pseudogene","termid":"PBO:0079404"}


id: PR:O75006
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sec15 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O75006"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exocyst complex component sec15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1183.01","synonyms":[{"name":"Spom972h-sec15","type":"exact"}],"termid":"PR:O75006"}


id: PBO:0043987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"colony stimulating factor 2 receptor subunit beta","termid":"PBO:0043987"}


id: PBO:0031652
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_rate_of_re-entry_into_mitotic_cell_cycle_after_pheromone_arrest","termid":"PBO:0031652"}


id: PBO:0065871
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAB27B, member RAS oncogene family","termid":"PBO:0065871"}


id: MONDO:0009387
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial lipoprotein lipase deficiency is a rare genetic disorder is which a person lacks the enzyme lipoprotein lipase, a protein needed to break down fat molecules. Deficiency of this enzyme prevents affected individuals from properly digesting certain fats. This results in the accumulation of fatty droplets called chylomicrons in the blood and an increase in the blood concentration of triglycerides. Symptoms include episodes of abdominal pain, recurrent inflammation of the pancreas (pancreatitis), abnormal enlargement of the liver and/or spleen (hepatosplenomegaly), and the development of skin lesions known as erruptive xanthomas. Familial lipoprotein lipase deficiency is caused by changes (mutations) in the LPL gene. It is inherited in an autosomal recessive pattern. Treatment aims to control symptoms and blood triglyceride levels with a very low-fat diet. Treatment for individual symptoms (i.e. pancreatitis) involves following established treatment guidelines.","direct_ancestors":[{"relation_name":"is_a","term_name":"familial hyperlipidemia","termid":"MONDO:0001336"},{"relation_name":"is_a","term_name":"syndromic dyslipidemia","termid":"MONDO:0015905"},{"relation_name":"is_a","term_name":"familial chylomicronemia syndrome","termid":"MONDO:0018637"},{"relation_name":"is_a","term_name":"hyperlipoproteinemia","termid":"MONDO:0037748"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005066"],"is_obsolete":false,"name":"familial lipoprotein lipase deficiency","secondary_identifiers":["GARD:12241","MEDGEN:7352","MESH:D008072","NORD:1129","icd11.foundation:1829539217","DOID:14118","SCTID:275598004","OMIM:238600","UMLS:C0023817","NCIT:C84771","ICD9:272.3","Orphanet:309015"],"synonyms":[{"name":"Burger-Grutz syndrome","type":"related"},{"name":"Fredrickson type I hyperlipoproteinemia","type":"exact"},{"name":"Fredrickson type I lipaemia","type":"exact"},{"name":"LPL deficiency","type":"exact"},{"name":"chylomicronemia, familial","type":"related"},{"name":"endogenous hypertriglyceridaemia","type":"related"},{"name":"familial LPL deficiency","type":"exact"},{"name":"familial chylomicronemia syndrome","type":"broad"},{"name":"familial fat-induced hypertriglyceridemia","type":"related"},{"name":"familial hyperchylomicronemia","type":"related"},{"name":"familial hyperlipoproteinemia type I","type":"exact"},{"name":"familial lipoprotein lipase deficiency (disorder) [ambiguous]","type":"exact"},{"name":"familial lipoprotein lipase deficiency with type I phenotype","type":"exact"},{"name":"high density lipoprotein cholesterol level QTL 11","type":"exact"},{"name":"hypercholesterinaemic xanthomatosis","type":"exact"},{"name":"hyperchylomicronemia","type":"exact"},{"name":"hyperchylomicronemia, familial","type":"related"},{"name":"hyperlipemia, essential familial","type":"related"},{"name":"hyperlipemia, idiopathic, Burger-Grutz type","type":"related"},{"name":"hyperlipoproteinemia type I","type":"broad"},{"name":"hyperlipoproteinemia, type 1","type":"broad"},{"name":"hyperlipoproteinemia, type 1A","type":"related"},{"name":"hyperlipoproteinemia, type I","type":"broad"},{"name":"lipase D deficiency","type":"related"},{"name":"lipd deficiency","type":"related"},{"name":"lipoprotein lipase deficiency","type":"related"},{"name":"lipoprotein lipase deficiency, familial","type":"related"},{"name":"mixed hyperglyceridemia","type":"exact"},{"name":"type I hyperlipoproteinemia","type":"broad"}],"termid":"MONDO:0009387","xrefs":{"Monarch":{"xref_id":"0009387"}}}


id: PBO:0076123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syntaxin binding protein 5L","termid":"PBO:0076123"}


id: PBO:0050690
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 8 pseudogene 17","termid":"PBO:0050690"}


id: PBO:0030604
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-coflocculating_cells","termid":"PBO:0030604"}


id: PBO:0084462
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication","termid":"PBO:0084462"}


id: GO:1903107
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any insulin receptor signaling pathway that is involved in dauer larval development.","definition_xrefs":["GOC:TermGenie","GOC:kmv","PMID:19853560","GO_REF:0000060"],"gene_count":0,"genotype_count":0,"name":"obsolete insulin receptor signaling pathway involved in dauer larval development (obsolete GO:1903107)","synonyms":[{"name":"daf-2 receptor signaling pathway involved in dauer larval development","type":"narrow"},{"name":"insulin receptor signalling pathway involved in dauer larval development","type":"exact"}],"termid":"GO:1903107"}


id: GO:0008981
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete protease IV activity (obsolete GO:0008981)","synonyms":[{"name":"protease IV activity","type":"exact"}],"termid":"GO:0008981"}


id: FYPO:0003672
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which ATP binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal ATP binding","termid":"FYPO:0003671"},{"relation_name":"is_a","term_name":"abolished molecular function","termid":"FYPO:0005446"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0000652","FYPO:0001985"],"is_obsolete":false,"name":"abolished ATP binding","synonyms":[{"name":"ATP binding abolished","type":"exact"}],"termid":"FYPO:0003672"}


id: GO:0030258
data:
  {"annotated_genes":["SJAG_00706","SJAG_04792"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76579],"is_not":false,"summary":null,"term":"GO:0030258"},{"annotations":[72867],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001561"}]},"cv_name":"biological_process","definition":"The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid metabolic process","termid":"GO:0006629"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00706":null,"SJAG_04792":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"lipid modification","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0030258","terms_by_termid":{"GO:0001561":null,"GO:0030258":null}}


id: PBO:0050139
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 49","termid":"PBO:0050139"}


id: MONDO:1010660
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Thrombocytopenia that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thrombocytopenia, non-human animal","termid":"MONDO:1010080"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombocytopenia, domestic cat","secondary_identifiers":["OMIA:001001-9685"],"termid":"MONDO:1010660","xrefs":{"Monarch":{"xref_id":"1010660"}}}


id: GO:0052017
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["ISBN:0198547684"],"gene_count":0,"genotype_count":0,"name":"obsolete catabolism by symbiont of host xylan (obsolete GO:0052017)","synonyms":[{"name":"catabolism by organism of host xylan","type":"exact"}],"termid":"GO:0052017"}


id: PBO:0071396
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L31 pseudogene 2","termid":"PBO:0071396"}


id: FYPO:0002504
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein modification","termid":"FYPO:0002497"},{"relation_name":"is_a","term_name":"abnormal protein palmitoylation","termid":"FYPO:0002503"},{"relation_name":"is_a","term_name":"abolished biological process","termid":"FYPO:0005448"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0002274","FYPO:0005447","FYPO:0001985","FYPO:0002494"],"is_obsolete":false,"name":"abolished protein palmitoylation","synonyms":[{"name":"protein palmitoylation abolished","type":"exact"},{"name":"protein palmitoylation absent","type":"exact"}],"termid":"FYPO:0002504"}


id: GO:0075223
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of sporangium germination.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of sporangium development","termid":"GO:0075310"},{"relation_name":"regulates","term_name":"sporangium germination","termid":"GO:0075222"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of sporangium germination","synonyms":[{"name":"modulation of sporangium germination","type":"narrow"},{"name":"modulation of sporangium germination on or near host","type":"narrow"}],"termid":"GO:0075223"}


id: PBO:0067876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 178","termid":"PBO:0067876"}


id: MONDO:0013832
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"keratoconus","termid":"MONDO:0015486"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"keratoconus 8","secondary_identifiers":["OMIM:614628","MEDGEN:766221","UMLS:C3553307"],"synonyms":[{"name":"KTCN8","type":"exact"},{"name":"keratoconus 8","type":"exact"}],"termid":"MONDO:0013832","xrefs":{"Monarch":{"xref_id":"0013832"}}}


id: PBO:0000484
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exosome 3'-5' exoribonuclease subunit Rrp6 (predicted)","termid":"PBO:0000484"}


id: MONDO:0011453
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ulnar ray dysgenesis with postaxial polydactyly and renal cystic dysplasia","secondary_identifiers":["UMLS:C1858422","MESH:C565783","MEDGEN:346903","OMIM:604380"],"synonyms":[{"name":"ulnar ray dysgenesis with postaxial polydactyly and renal cystic dysplasia","type":"exact"}],"termid":"MONDO:0011453","xrefs":{"Monarch":{"xref_id":"0011453"}}}


id: MONDO:0006428
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A diffuse large B-cell lymphoma occurring in the spleen.","definition_xrefs":["NCIT:C7308"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diffuse large B-cell lymphoma","termid":"MONDO:0018905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"splenic diffuse large B-cell lymphoma","secondary_identifiers":["EFO:1000547","MEDGEN:412154","UMLS:C2018774"],"synonyms":[{"name":"primary splenic diffuse large B-cell lymphoma","type":"exact"},{"name":"splenic diffuse large B-cell lymphoma","type":"exact"}],"termid":"MONDO:0006428","xrefs":{"Monarch":{"xref_id":"0006428"}}}


id: FYPO:0002063
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a 3'-5'-exoribonuclease activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal ribonuclease activity","termid":"FYPO:0003821"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000707","FYPO:0001985","FYPO:0000652","FYPO:0000661"],"is_obsolete":false,"name":"abnormal 3'-5'-exoribonuclease activity","termid":"FYPO:0002063"}


id: PBO:0091080
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER membrane organization protein, HVA22/TB2/DP1 family protein","termid":"PBO:0091080"}


id: PBO:0008038
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vitamin H transporter (predicted)","termid":"PBO:0008038"}


id: PBO:0054889
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2303","termid":"PBO:0054889"}


id: PBO:0062336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 6 subfamily C member 75","termid":"PBO:0062336"}


id: PBO:0002385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucan beta-glucosidase Bgl2 (predicted)","termid":"PBO:0002385"}


id: GO:0061451
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neural nucleus development","termid":"GO:0048857"},{"relation_name":"part_of","term_name":"medulla oblongata development","termid":"GO:0021550"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"retrotrapezoid nucleus development","termid":"GO:0061451"}


id: PBO:0079257
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TTC28 antisense RNA 1","termid":"PBO:0079257"}


id: MOD:00756
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-valine residue to 4-hydroxy-D-valine.","definition_xrefs":["RESID:AA0388","PubMed:15853325"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monohydroxylated residue","termid":"MOD:00425"},{"relation_name":"is_a","term_name":"stereoisomerized residue","termid":"MOD:00664"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4-hydroxy-D-valine","synonyms":[{"name":"(2R,3Xi)-2-amino-4-hydroxy-3-methylbutanoic acid","type":"exact"},{"name":"4-hydroxy-D-valine","type":"exact"},{"name":"D-4HyVal","type":"exact"},{"name":"D-gamma-hydroxyvaline","type":"exact"},{"name":"MOD_RES D-4-hydroxyvaline","type":"exact"}],"termid":"MOD:00756"}


id: PBO:0041977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 18","termid":"PBO:0041977"}


id: PBO:0044442
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 4 subfamily F member 11","termid":"PBO:0044442"}


id: MONDO:0019329
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"lymphangioma","termid":"MONDO:0002013"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"microcystic lymphatic malformation","secondary_identifiers":["Orphanet:79490","GARD:13020","icd11.foundation:1796778763","MEDGEN:1843242","UMLS:C4738056"],"synonyms":[{"name":"capillary lymphangioma","type":"related"},{"name":"capillary lymphatic malformation","type":"exact"},{"name":"cutaneous lymphangioma circumscriptum","type":"exact"},{"name":"microcystic infiltrating lymphatic malformation","type":"exact"},{"name":"microcystic lymphangioma","type":"exact"},{"name":"superficial lymphangioma","type":"exact"},{"name":"superficial lymphatic malformation","type":"exact"}],"termid":"MONDO:0019329","xrefs":{"Monarch":{"xref_id":"0019329"}}}


id: GO:0007458
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc.","definition_xrefs":["PMID:3076112","PMID:3937883"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"compound eye morphogenesis","termid":"GO:0001745"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"progression of morphogenetic furrow involved in compound eye morphogenesis","synonyms":[{"name":"progression of morphogenetic furrow during compound eye morphogenesis","type":"related"}],"termid":"GO:0007458"}


id: PBO:0028960
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-galactose_absent_from_glycoprotein_glycan","termid":"PBO:0028960"}


id: PBO:0038579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activator of basal transcription 1","termid":"PBO:0038579"}


id: PR:O94696
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC83.12 gene.","definition_xrefs":["UniProtKB:O94696","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C83.12 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC83.12","synonyms":[{"name":"Spom972h-SPBC83.12","type":"exact"}],"termid":"PR:O94696"}


id: PBO:0079251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TTC23 antisense RNA 1","termid":"PBO:0079251"}


id: PBO:0059855
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methylenetetrahydrofolate reductase","termid":"PBO:0059855"}


id: PBO:0082461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Calcineurin A; one isoform (the other is Cmp2p) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1; regulates the function of Aly1p alpha-arrestin; CNA1 has a paralog, CMP2, that arose from the whole genome duplication","termid":"PBO:0082461"}


id: MONDO:0010003
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rowley-Rosenberg syndrome","secondary_identifiers":["SCTID:53783003","OMIM:268500","UMLS:C0268426","MESH:C535874","MEDGEN:120638"],"synonyms":[{"name":"Growth retardation, pulmonary hypertension, and amino aciduria","type":"related"},{"name":"Growth retardation, pulmonary hypertension, and aminoaciduria","type":"related"},{"name":"Rowley-Rosenberg syndrome","type":"exact"}],"termid":"MONDO:0010003","xrefs":{"Monarch":{"xref_id":"0010003"}}}


id: MONDO:0060490
data:
  {"annotated_genes":["SJAG_03964"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86471],"is_not":false,"summary":null,"term":"MONDO:0060490"}]},"cv_name":"mondo","definition":"A rare genetic syndromic intellectual disability characterized by infantile onset of global developmental delay and profound intellectual disability in association with a heterogeneous spectrum of manifestations, such as features of lower motor neuron disease, hypotonia, spasticity, contractures, seizures, respiratory insufficiency, and optic atrophy, among others. Dysmorphic craniofacial features include microcephaly, tall forehead, bitemporal narrowing, flat nasal bridge, low-set ears, and high-arched palate. Brain imaging may show cerebral and cerebellar atrophy, delayed myelination, and thin corpus callosum.","definition_xrefs":["Orphanet:544469"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03964":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4479566","MEDGEN:1380860","GARD:17985","OMIM:617481"],"synonyms":[{"name":"NMIHBA","type":"related"},{"name":"neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies","type":"exact"}],"termid":"MONDO:0060490","terms_by_termid":{"MONDO:0060490":null},"xrefs":{"Monarch":{"xref_id":"0060490"}}}


id: PBO:0056589
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MyoD family inhibitor","termid":"PBO:0056589"}


id: PBO:0066103
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RasGEF domain family member 1A","termid":"PBO:0066103"}


id: PBO:0006832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin-like protein, Ino80 complex subunit Arp8","termid":"PBO:0006832"}


id: PBO:0065072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRICKLE2 antisense RNA 1","termid":"PBO:0065072"}


id: PBO:0072628
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"R-spondin 3","termid":"PBO:0072628"}


id: PBO:0078605
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 60 pseudogene 18","termid":"PBO:0078605"}


id: PBO:0052911
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin associated protein 13-3","termid":"PBO:0052911"}


id: MONDO:0014864
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypermanganesemia with dystonia in which the cause of the disease is a mutation in the SLC39A14 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypermanganesemia with dystonia","termid":"MONDO:0000214"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"disorder of manganese transport","termid":"MONDO:0017766"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0006025"],"is_obsolete":false,"name":"hypermanganesemia with dystonia 2","secondary_identifiers":["UMLS:C4310765","OMIM:617013","DOID:0080537","Orphanet:521406","GARD:17958","SCTID:768554008","MEDGEN:934732"],"synonyms":[{"name":"HMNDYT2","type":"exact"},{"name":"SLC39A14 hypermanganesemia with dystonia","type":"exact"},{"name":"hypermanganesemia with dystonia 2","type":"exact"},{"name":"hypermanganesemia with dystonia 2; HMNDYT2","type":"exact"},{"name":"hypermanganesemia with dystonia caused by mutation in SLC39A14","type":"exact"},{"name":"hypermanganesemia with dystonia type 2","type":"exact"}],"termid":"MONDO:0014864","xrefs":{"Monarch":{"xref_id":"0014864"}}}


id: GO:0033945
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.","definition_xrefs":["EC:3.2.1.150"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016798"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787","GO:0016798"],"is_obsolete":false,"name":"oligoxyloglucan reducing-end-specific cellobiohydrolase activity","secondary_identifiers":["MetaCyc:3.2.1.150-RXN"],"synonyms":[{"name":"oligoxyloglucan reducing end-specific cellobiohydrolase activity","type":"related"},{"name":"oligoxyloglucan reducing-end cellobiohydrolase activity","type":"related"}],"termid":"GO:0033945"}


id: GO:0010924
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.","definition_xrefs":["GOC:dph","GOC:BHF","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of inositol-polyphosphate 5-phosphatase activity (obsolete GO:0010924)","termid":"GO:0010924"}


id: PBO:0085210
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Oxysterol-binding  phosphatidylserine transferase; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuolar fusion; OSH6 has a paralog, OSH7, that arose from the whole genome duplication","termid":"PBO:0085210"}


id: PBO:0004517
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.3.1.97","termid":"PBO:0004517"}


id: GO:1902749
data:
  {"annotated_genes":["SJAG_00082","SJAG_03026","SJAG_06592","SJAG_02332","SJAG_01010","SJAG_02576","SJAG_04280","SJAG_01205","SJAG_02771","SJAG_01855","SJAG_01901","SJAG_02266","SJAG_02723","SJAG_03942","SJAG_01000","SJAG_01605","SJAG_01805","SJAG_01084","SJAG_03695","SJAG_03067","SJAG_03602","SJAG_01837","SJAG_01456","SJAG_00216","SJAG_02392","SJAG_01429","SJAG_02342","SJAG_04671","SJAG_01076","SJAG_03160","SJAG_02074","SJAG_04486","SJAG_03592","SJAG_02858","SJAG_04332","SJAG_00526","SJAG_00214","SJAG_04394","SJAG_00364","SJAG_01146","SJAG_03073","SJAG_00318","SJAG_00883","SJAG_04287","SJAG_03854","SJAG_04140","SJAG_03486","SJAG_05373","SJAG_03048","SJAG_01680","SJAG_03309","SJAG_01873","SJAG_00256","SJAG_00600","SJAG_00117","SJAG_02592","SJAG_02563","SJAG_04597","SJAG_03927","SJAG_01044","SJAG_02098","SJAG_03126","SJAG_01118","SJAG_00640"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[106413,115868,91186],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033315"},{"annotations":[94167,100323,89743,101223,115813],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044878"},{"annotations":[106416,91187,109118,111832,116611,117085,99145,71913,78594,116912,93720,79174,100324,98978,74494,115870,70762],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033314"},{"annotations":[98213,95611,94299,115815],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031569"},{"annotations":[100325,111527,74944,91188,91551,117524,89962,100838,88867,99147,106417,79037,116826,109119,71911],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007095"},{"annotations":[92974,78226,100783,104287,93324,106448,108375,92682,111233,111618,106812,112276,114274,94127],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010972"},{"annotations":[78230,70243],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110031"},{"annotations":[110142,116294,108377,87794,98214,94130,110998,116482,101546,94169,73241,98785,91491,93560,87803,70563,103280,91895,107035],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010971"},{"annotations":[101173,87595],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905287"},{"annotations":[73246],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110032"},{"annotations":[71141,111763],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010389"}]},"cv_name":"biological_process","definition":"Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell cycle phase transition","termid":"GO:1901987"},{"relation_name":"regulates","term_name":"cell cycle G2/M phase transition","termid":"GO:0044839"}],"gene_count":64,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_00117":null,"SJAG_00214":null,"SJAG_00216":null,"SJAG_00256":null,"SJAG_00318":null,"SJAG_00364":null,"SJAG_00526":null,"SJAG_00600":null,"SJAG_00640":null,"SJAG_00883":null,"SJAG_01000":null,"SJAG_01010":null,"SJAG_01044":null,"SJAG_01076":null,"SJAG_01084":null,"SJAG_01118":null,"SJAG_01146":null,"SJAG_01205":null,"SJAG_01429":null,"SJAG_01456":null,"SJAG_01605":null,"SJAG_01680":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_01855":null,"SJAG_01873":null,"SJAG_01901":null,"SJAG_02074":null,"SJAG_02098":null,"SJAG_02266":null,"SJAG_02332":null,"SJAG_02342":null,"SJAG_02392":null,"SJAG_02563":null,"SJAG_02576":null,"SJAG_02592":null,"SJAG_02723":null,"SJAG_02771":null,"SJAG_02858":null,"SJAG_03026":null,"SJAG_03048":null,"SJAG_03067":null,"SJAG_03073":null,"SJAG_03126":null,"SJAG_03160":null,"SJAG_03309":null,"SJAG_03486":null,"SJAG_03592":null,"SJAG_03602":null,"SJAG_03695":null,"SJAG_03854":null,"SJAG_03927":null,"SJAG_03942":null,"SJAG_04140":null,"SJAG_04280":null,"SJAG_04287":null,"SJAG_04332":null,"SJAG_04394":null,"SJAG_04486":null,"SJAG_04597":null,"SJAG_04671":null,"SJAG_05373":null,"SJAG_06592":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"regulation of cell cycle G2/M phase transition","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-8852276"],"termid":"GO:1902749","terms_by_termid":{"GO:0007095":null,"GO:0010389":null,"GO:0010971":null,"GO:0010972":null,"GO:0031569":null,"GO:0033314":null,"GO:0033315":null,"GO:0044878":null,"GO:0110031":null,"GO:0110032":null,"GO:1905287":null}}


id: GO:0019299
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexose metabolic process","termid":"GO:0019318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0005975","GO:0008150"],"is_obsolete":false,"name":"rhamnose metabolic process","synonyms":[{"name":"rhamnose metabolism","type":"exact"}],"termid":"GO:0019299"}


id: PR:Q10095
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC11D3.16c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10095"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C11D3.16c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC11D3.16c","synonyms":[{"name":"Spom972h-SPAC11D3.16c","type":"exact"}],"termid":"PR:Q10095"}


id: GO:1990881
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.","definition_xrefs":["PMID:26150418"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of transcription from RNA polymerase II promoter in response to DNA damage (obsolete GO:1990881)","synonyms":[{"name":"down regulation of transcription from RNA polymerase II promoter in response to DNA damage","type":"exact"},{"name":"down-regulation of transcription from RNA polymerase II promoter in response to DNA damage","type":"exact"},{"name":"downregulation of transcription from RNA polymerase II promoter in response to DNA damage","type":"exact"},{"name":"inhibition of transcription from RNA polymerase II promoter in response to DNA damage","type":"exact"}],"termid":"GO:1990881"}


id: MONDO:0100494
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant form of TTN-related myopathy.","definition_xrefs":["MONDO:patterns/autosomal_dominant"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"TTN-related myopathy","termid":"MONDO:0100175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0005336","MONDO:0002320"],"is_obsolete":false,"name":"autosomal dominant titinopathy","synonyms":[{"name":"TTN-related myopathy, autosomal dominant","type":"exact"}],"termid":"MONDO:0100494","xrefs":{"Monarch":{"xref_id":"0100494"}}}


id: PBO:0075227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 3 pseudogene 1 X-linked","termid":"PBO:0075227"}


id: GO:1903123
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity.","definition_xrefs":["GOC:TermGenie","GOC:bf","GO_REF:0000059","GOC:PARL"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of thioredoxin peroxidase activity (obsolete GO:1903123)","synonyms":[{"name":"regulation of TPx activity","type":"exact"},{"name":"regulation of TrxPx activity","type":"exact"},{"name":"regulation of thiol peroxidase activity","type":"exact"}],"termid":"GO:1903123"}


id: MONDO:0033662
data:
  {"annotated_genes":["SJAG_03357"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85521],"is_not":false,"summary":null,"term":"MONDO:0033662"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03357":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with microcephaly, seizures, and brain atrophy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:619076","UMLS:C5436747","GARD:18532","MEDGEN:1755716"],"synonyms":[{"name":"NEDMISB","type":"exact"}],"termid":"MONDO:0033662","terms_by_termid":{"MONDO:0033662":null},"xrefs":{"Monarch":{"xref_id":"0033662"}}}


id: MONDO:0000950
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Term generally used to describe complaints related to refractive error, ocular muscle imbalance, including pain or aching around the eyes, burning and itchiness of the eyelids, ocular fatigue, and headaches.","definition_xrefs":["MESH:D001248"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"asthenopia","secondary_identifiers":["DOID:10141","UMLS:C0004095","MEDGEN:2108"],"synonyms":[{"name":"accommodative strain","type":"exact"}],"termid":"MONDO:0000950","xrefs":{"Monarch":{"xref_id":"0000950"}}}


id: PBO:0050605
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydroxysteroid 17-beta dehydrogenase 1","termid":"PBO:0050605"}


id: PATO:0000911
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A rate which is relatively low.","definition_xrefs":["PATO:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"rate","termid":"PATO:0000161"},{"relation_name":"is_a","term_name":"decreased process quality","termid":"PATO:0002302"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased rate","synonyms":[{"name":"slow rate","type":"exact"}],"termid":"PATO:0000911"}


id: MOD:00223
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-lysine residue to N6-mureinyl-L-lysine.","definition_xrefs":["RESID:AA0218","PubMed:4261992"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidoglycanated residue","termid":"MOD:01159"},{"relation_name":"is_a","term_name":"N6-acylated L-lysine","termid":"MOD:01875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"},{"rel_name":"is_a","termid":"MOD:01875"}],"interesting_parent_ids":["MOD:01875","MOD:00764"],"is_obsolete":false,"name":"N6-mureinyl-L-lysine","synonyms":[{"name":"MOD_RES N6-murein peptidoglycan lysine","type":"exact"},{"name":"N6-[(2R,6S)-2-(N-(N-mureinyl-(R)-alanyl)-(S)-glutamyl)amino-6-amino-6-carboxy-1-oxohex-1-yl]lysine","type":"exact"},{"name":"N6-mureinyl-L-lysine","type":"exact"}],"termid":"MOD:00223"}


id: PR:O94432
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A CUGBP Elav-like family member 4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02371","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized RNA-binding protein C660.15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC660.15","secondary_identifiers":["UniProtKB:O94432"],"synonyms":[{"name":"Spom972h-CELF4","type":"exact"}],"termid":"PR:O94432"}


id: PBO:0083684
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Endosomal subunit of membrane-associated retromer complex; required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p; overexpression of wild-type human VPS35 or Parkinson's-associated vps35-D686N or vps35-P299S variants complements Ni2+ resistance and Cd2+ sensitivity of yeast vps35 null mutant","termid":"PBO:0083684"}


id: GO:0101031
data:
  {"annotated_genes":["SJAG_00447","SJAG_01002","SJAG_03570","SJAG_03320","SJAG_00609","SJAG_04121","SJAG_02926","SJAG_02378"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[73206,79541,76547,77716,72410,75770,69400,77915],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005832"}]},"cv_name":"cellular_component","definition":"A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.","definition_xrefs":["GOC:bhm","PMID:21855797"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein-containing complex","termid":"GO:0140535"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00447":null,"SJAG_00609":null,"SJAG_01002":null,"SJAG_02378":null,"SJAG_02926":null,"SJAG_03320":null,"SJAG_03570":null,"SJAG_04121":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"protein folding chaperone complex","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"chaperone complex","type":"broad"}],"termid":"GO:0101031","terms_by_termid":{"GO:0005832":null}}


id: GO:0008553
data:
  {"annotated_genes":["SJAG_01669","SJAG_04258","SJAG_01129","SJAG_04167"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70255,72884,77603],"is_not":false,"summary":null,"term":"GO:0008553"},{"annotations":[112148],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008900"}]},"cv_name":"molecular_function","definition":"Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.","definition_xrefs":["RHEA:20852"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proton transmembrane transporter activity","termid":"GO:0015078"},{"relation_name":"is_a","term_name":"P-type ion transporter activity","termid":"GO:0015662"},{"relation_name":"is_a","term_name":"ATPase-coupled monoatomic cation transmembrane transporter activity","termid":"GO:0019829"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01129":null,"SJAG_01669":null,"SJAG_04167":null,"SJAG_04258":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"P-type proton-exporting transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["EC:7.1.2.1","GO:0036442","MetaCyc:3.6.3.6-RXN"],"synonyms":[{"name":"H+-exporting ATPase activity","type":"related"},{"name":"H+-transporting ATPase","type":"broad"},{"name":"H+-transporting ATPase activity","type":"broad"},{"name":"P-type H+-exporting ATPase activity","type":"broad"},{"name":"hydrogen exporting ATPase activity, phosphorylative mechanism","type":"exact"},{"name":"hydrogen-/sodium-translocating ATPase activity","type":"related"},{"name":"hydrogen-exporting ATPase activity","type":"broad"},{"name":"hydrogen-exporting ATPase activity, phosphorylative mechanism","type":"related"},{"name":"proton transport ATPase activity","type":"related"},{"name":"proton-exporting ATPase activity","type":"broad"},{"name":"proton-exporting ATPase activity, phosphorylative mechanism","type":"related"},{"name":"proton-translocating ATPase activity","type":"related"},{"name":"proton-transporting ATPase activity","type":"exact"}],"termid":"GO:0008553","terms_by_termid":{"GO:0008553":null,"GO:0008900":null}}


id: GO:0097684
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The anterior most point of a dinoflagellate hypocone.","definition_xrefs":["GOC:at","Wikipedia:Dinoflagellate#Morphology"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"dinoflagellate hypocone","termid":"GO:0097614"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"dinoflagellate antapex","synonyms":[{"name":"antapex","type":"broad"}],"termid":"GO:0097684"}


id: GO:0032376
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of sterol transport","termid":"GO:0032373"},{"relation_name":"is_a","term_name":"regulation of cholesterol transport","termid":"GO:0032374"},{"relation_name":"positively_regulates","term_name":"cholesterol transport","termid":"GO:0030301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of cholesterol transport","synonyms":[{"name":"activation of cholesterol transport","type":"narrow"},{"name":"stimulation of cholesterol transport","type":"narrow"},{"name":"up regulation of cholesterol transport","type":"exact"},{"name":"up-regulation of cholesterol transport","type":"exact"},{"name":"upregulation of cholesterol transport","type":"exact"}],"termid":"GO:0032376"}


