# terms

id: GO:0009413
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to stress","termid":"GO:0006950"},{"relation_name":"is_a","term_name":"response to water","termid":"GO:0009415"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to flooding","termid":"GO:0009413"}


id: PBO:0034237
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_taxon","termid":"PBO:0034237"}


id: MONDO:0010496
data:
  {"annotated_genes":["SJAG_00992"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85061],"is_not":false,"summary":null,"term":"MONDO:0010496"}]},"cv_name":"mondo","definition":"X-linked intellectual disability-short stature-overweight syndrome is a multiple congenital anomalies syndrome characterized by borderline to severe intellectual disability, speech delay, short stature, elevated body mass index, a pattern of truncal obesity (reported in older males), and variable neurologic features (e.g. hypotonia, tremors, gait disturbances, behavioral problems, and seizure disorders). Less common manifestations include microcephaly, microorchidism and/or microphallus. Dysmorphic features have been reported in some patients but no consistent pattern has been noted.","definition_xrefs":["Orphanet:457240"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00992":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"X-linked intellectual disability-short stature-overweight syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:17800","DOID:0112056","MEDGEN:901885","OMIM:300957","UMLS:C0796218"],"synonyms":[{"name":"MRX12","type":"related"},{"name":"intellectual developmental disorder, X-linked 12, X-linked recessive","type":"exact"},{"name":"intellectual disability, X-linked 12","type":"related"},{"name":"intellectual disability, X-linked 35","type":"related"},{"name":"intellectual disability, X-linked type 12","type":"exact"},{"name":"mental retardation, X-linked 12","type":"related"},{"name":"mental retardation, X-linked 35","type":"related"},{"name":"mental retardation, X-linked type 12","type":"exact"}],"termid":"MONDO:0010496","terms_by_termid":{"MONDO:0010496":null},"xrefs":{"Monarch":{"xref_id":"0010496"}}}


id: MONDO:0044871
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"focal dystonia","termid":"MONDO:0000477"},{"relation_name":"is_a","term_name":"inherited dystonia","termid":"MONDO:0044807"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"dystonia, focal, task-specific","secondary_identifiers":["MEDGEN:370752","MESH:C566973","SCTID:230330004","GARD:6458","OMIM:611284","UMLS:C1969807"],"synonyms":[{"name":"FTSD","type":"exact"},{"name":"dystonia, focal, task-specific","type":"exact"},{"name":"focal hand dystonia","type":"related"},{"name":"focal task-specific dystonia","type":"related"},{"name":"musician's cramp","type":"exact"},{"name":"musician's dystonia","type":"related"},{"name":"occupational cramp","type":"related"},{"name":"occupational dystonia","type":"related"},{"name":"task-specific dystonia","type":"related"},{"name":"task-specific focal dystonia","type":"related"}],"termid":"MONDO:0044871","xrefs":{"Monarch":{"xref_id":"0044871"}}}


id: MONDO:0004373
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A papillary meningioma occurring in adults.","definition_xrefs":["NCIT:C8293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rhabdoid meningioma","termid":"MONDO:0003262"},{"relation_name":"is_a","term_name":"papillary meningioma","termid":"MONDO:0021088"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adult papillary meningioma","secondary_identifiers":["UMLS:C0281334","DOID:7826","MEDGEN:76256"],"synonyms":[{"name":"adult papillary meningioma","type":"exact"},{"name":"papillary meningioma","type":"broad"},{"name":"papillary meningioma of adults","type":"exact"}],"termid":"MONDO:0004373","xrefs":{"Monarch":{"xref_id":"0004373"}}}


id: MONDO:0005876
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with viruses of the order nidovirales. The concept includes arterivirus infections and coronaviridae infections.","definition_xrefs":["MESH:D030341"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary viral infectious disease","termid":"MONDO:0100329"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nidovirales infectious disease","secondary_identifiers":["MEDGEN:197455","UMLS:C0969753"],"synonyms":[{"name":"Nidovirales caused disease or disorder","type":"exact"},{"name":"Nidovirales disease or disorder","type":"exact"}],"termid":"MONDO:0005876","xrefs":{"Monarch":{"xref_id":"0005876"}}}


id: PBO:0061403
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NPR2 like, GATOR1 complex subunit","termid":"PBO:0061403"}


id: GO:0045034
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The asymmetrical division of a neuroblast, the neural precursor in the central nervous system, giving rise to another neuroblast and a ganglion mother cell.","definition_xrefs":["PMID:11250167","PMID:11163136"],"gene_count":0,"genotype_count":0,"name":"obsolete neuroblast division (obsolete GO:0045034)","synonyms":[{"name":"neuroblast cell division","type":"exact"},{"name":"neuroblast division","type":"exact"},{"name":"neuroblast division (sensu Nematoda and Protostomia)","type":"exact"},{"name":"neuroblast division (sensu Vertebrata)","type":"exact"}],"termid":"GO:0045034"}


id: PBO:0063653
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoglycerate mutase 1 pseudogene 10","termid":"PBO:0063653"}


id: PBO:0069677
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 954, pseudogene","termid":"PBO:0069677"}


id: PBO:0051901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"integrin subunit alpha 9","termid":"PBO:0051901"}


id: PBO:0054853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2267","termid":"PBO:0054853"}


id: GO:0060130
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glandular epithelial cell development","termid":"GO:0002068"},{"relation_name":"is_a","term_name":"neuron development","termid":"GO:0048666"},{"relation_name":"part_of","term_name":"thyroid-stimulating hormone-secreting cell differentiation","termid":"GO:0060129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"thyroid-stimulating hormone-secreting cell development","synonyms":[{"name":"TSH-secreting cell development","type":"exact"},{"name":"beta-basophil development","type":"exact"},{"name":"thyroid stimulating hormone secreting cell development","type":"exact"},{"name":"thyrotrope development","type":"exact"},{"name":"thyrotroph development","type":"exact"}],"termid":"GO:0060130"}


id: PR:B5BP49
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC460.05 gene.","definition_xrefs":["PRO:DNx","UniProtKB:B5BP49"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized transporter C460.05 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC460.05","synonyms":[{"name":"Spom972h-SPBC460.05","type":"exact"}],"termid":"PR:B5BP49"}


id: MONDO:0007158
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Distal arthrogryposis type 5 is an inherited developmental defect syndrome characterized by multiple congenital contractures of limbs, without primary neurologic and/or muscle disease that affects limb function, and ocular anomalies (ptosis, external ophtalmoplegia and/or strabismus). Intelligence is normal.","definition_xrefs":["Orphanet:1154"],"direct_ancestors":[{"relation_name":"is_a","term_name":"distal arthrogryposis","termid":"MONDO:0019942"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis- oculomotor limitation-electroretinal anomalies syndrome","secondary_identifiers":["GARD:4047","UMLS:C1862472","SCTID:715217004","MEDGEN:350678","DOID:0111608","OMIM:108145"],"synonyms":[{"name":"Arthogryposis with oculomotor limitation and electroretinal abnormalities","type":"related"},{"name":"DA5","type":"related"},{"name":"arthrogryposis ophthalmoplegia retinopathy","type":"related"},{"name":"arthrogryposis with oculomotor limitation and electroretinal abnormalities","type":"related"},{"name":"arthrogryposis, distal, type 2B","type":"related"},{"name":"arthrogryposis, distal, type 5","type":"related"},{"name":"arthrogryposis- oculomotor limitation-electroretinal anomalies syndrome","type":"exact"},{"name":"arthrogryposis-oculomotor limitation-electroretinal anomalies syndrome","type":"related"},{"name":"distal arthrogryposis type 5","type":"exact"},{"name":"distal arthrogryposis type IIB","type":"exact"},{"name":"distal arthrogryposis with ophthalmoplegia","type":"exact"},{"name":"oculomelic amyoplasia","type":"exact"}],"termid":"MONDO:0007158","xrefs":{"Monarch":{"xref_id":"0007158"}}}


id: GO:0097434
data:
  {"annotated_genes":["SJAG_01406"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[101450],"is_not":false,"summary":null,"term":"GO:0097434"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in).","definition_xrefs":["GOC:al","PMID:1293882"],"direct_ancestors":[{"relation_name":"is_a","term_name":"succinate transmembrane transporter activity","termid":"GO:0015141"},{"relation_name":"is_a","term_name":"solute:proton symporter activity","termid":"GO:0015295"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01406":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"succinate:proton symporter activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["RHEA:29303"],"synonyms":[{"name":"succinate:hydrogen symporter activity","type":"exact"}],"termid":"GO:0097434","terms_by_termid":{"GO:0097434":null}}


id: PBO:0047672
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FLG antisense RNA 1","termid":"PBO:0047672"}


id: GO:0004903
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.","definition_xrefs":["GOC:ai","GOC:signaling"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine receptor activity","termid":"GO:0004896"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"growth hormone receptor activity","termid":"GO:0004903"}


id: PR:000027541
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A transcription factor ste11 unmodified form in Schizosaccharomyces pombe.","definition_xrefs":["PMID:11702950","PomBase:MAH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription factor ste11","termid":"PR:000027538"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor ste11 unmodified form (Schizosaccharomyces pombe)","pombase_gene_id":"SPBC32C12.02","synonyms":[{"name":"Spom-ste11/UnMod","type":"exact"}],"termid":"PR:000027541"}


id: MONDO:0008472
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Spondyloepiphyseal dysplasia (SED), MacDermot type is characterized by short stature, femoral epiphyseal dysplasia, mild vertebral changes and sensorineural deafness.","definition_xrefs":["Orphanet:163668"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spondyloepiphyseal dysplasia","termid":"MONDO:0016761"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"spondyloepiphyseal dysplasia, MacDermot type","secondary_identifiers":["GARD:16996","MESH:C566659","MEDGEN:401067","UMLS:C1866719","OMIM:184000","icd11.foundation:800575171"],"synonyms":[{"name":"spondyloepiphyseal dysplasia, myopia, and sensorineural deafness","type":"related"},{"name":"spondyloepiphyseal dysplasia-myopia-sensorineural deafness syndrome","type":"exact"}],"termid":"MONDO:0008472","xrefs":{"Monarch":{"xref_id":"0008472"}}}


id: PBO:0090221
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA/snRNA/rRNA pseudouridine synthase Pus7","termid":"PBO:0090221"}


id: MONDO:0006579
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, darkly pigmented skin lesion characterized by proliferation of keratinocytes and melanocytes.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"seborrheic keratosis","termid":"MONDO:0008420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"melanoacanthoma","secondary_identifiers":["MEDGEN:272110","DOID:11684","UMLS:C1321683","EFO:1000733","NCIT:C27548","Wikipedia:Melanocanthoma","SCTID:394727000"],"termid":"MONDO:0006579","xrefs":{"Monarch":{"xref_id":"0006579"}}}


id: PBO:0042751
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centromere protein V like 1","termid":"PBO:0042751"}


id: PBO:0091698
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by S. cerevisiae sgt1","termid":"PBO:0091698"}


id: GO:0106129
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of store-operated calcium entry.","definition_xrefs":["GOC:BHF","GOC:rph","PMID:23447642","GOC:BHF_miRNA"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of calcium ion transport","termid":"GO:0051928"},{"relation_name":"is_a","term_name":"regulation of store-operated calcium entry","termid":"GO:2001256"},{"relation_name":"positively_regulates","term_name":"store-operated calcium entry","termid":"GO:0002115"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of store-operated calcium entry","termid":"GO:0106129"}


id: PBO:0064288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasminogen","termid":"PBO:0064288"}


id: FYPO:0004096
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the cytoskeleton is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization","termid":"FYPO:0003627"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0000138"],"is_obsolete":false,"name":"normal protein localization to cytoskeleton","synonyms":[{"name":"normal protein localisation to cytoskeleton","type":"exact"}],"termid":"FYPO:0004096"}


id: PBO:0002087
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA-binding protein Nop12 (predicted)","termid":"PBO:0002087"}


id: PBO:0027102
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_rDNA_antisense_small_RNA_level","termid":"PBO:0027102"}


id: MONDO:0016483
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An intracranial aneurysm with a characteristic rounded shape; the most common form of cerebral aneurysm.","definition_xrefs":["DOID:0060228"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brain aneurysm","termid":"MONDO:0005291"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intracranial berry aneurysm","secondary_identifiers":["UMLS:C3839866","SCTID:703226008","icd11.foundation:59881644","GARD:17161","MEDGEN:825711","OMIMPS:105800","Orphanet:231160","HP:0007029"],"synonyms":[{"name":"aneurysm, intracranial berry","type":"exact"},{"name":"familial aneurysmal subarachnoid haemorrhage","type":"exact"},{"name":"familial aneurysmal subarachnoid hemorrhage","type":"exact"},{"name":"familial berry aneurysm","type":"exact"},{"name":"familial cerebral saccular aneurysm","type":"related"},{"name":"familial intracranial saccular aneurysm","type":"exact"},{"name":"saccular cerebral aneurysm","type":"exact"}],"termid":"MONDO:0016483","xrefs":{"Monarch":{"xref_id":"0016483"}}}


id: PBO:0116857
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleolar DNAJ domain protein, DNAJC9 family","termid":"PBO:0116857"}


id: PBO:0031871
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP Citrate Lyase","termid":"PBO:0031871"}


id: GO:0007077
data:
  {"annotated_genes":["SJAG_04578","SJAG_00840","SJAG_00680"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[110259],"is_not":false,"summary":null,"term":"GO:0007077"},{"annotations":[103451],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140516"},{"annotations":[93596,103454],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:1905557"}]},"cv_name":"biological_process","definition":"The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.","definition_xrefs":["PMID:32848252","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear membrane disassembly","termid":"GO:0051081"},{"relation_name":"is_a","term_name":"mitotic cell cycle process","termid":"GO:1903047"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00680":null,"SJAG_00840":null,"SJAG_04578":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0007049","GO:0061024","GO:0008150"],"is_obsolete":false,"name":"mitotic nuclear membrane disassembly","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-2980766"],"synonyms":[{"name":"NEB","type":"broad"},{"name":"local NEB","type":"broad"},{"name":"mitotic nuclear envelope breakdown","type":"exact"},{"name":"mitotic nuclear envelope catabolism","type":"related"},{"name":"mitotic nuclear envelope degradation","type":"related"},{"name":"mitotic nuclear envelope disassembly","type":"related"},{"name":"nuclear envelope breakdown","type":"broad"}],"termid":"GO:0007077","terms_by_termid":{"GO:0007077":null,"GO:0140516":null,"GO:1905557":null}}


id: PBO:0057047
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 135a-2","termid":"PBO:0057047"}


id: GO:0072732
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to starvation","termid":"GO:0009267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to calcium ion starvation","synonyms":[{"name":"cellular response to calcium starvation","type":"exact"}],"termid":"GO:0072732"}


id: SO:0001611
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An elongation of a polypeptide sequence at the N terminus deriving from a sequence variant extending the CDS.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"CDS_five_prime_extension","termid":"SO:0002228"},{"relation_name":"is_a","term_name":"elongated_polypeptide","termid":"SO:0001609"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongated_polypeptide_N_terminal","synonyms":[{"name":"elongated polypeptide N terminal","type":"exact"}],"termid":"SO:0001611"}


id: GO:0006888
data:
  {"annotated_genes":["SJAG_04434","SJAG_01633","SJAG_03499","SJAG_02824","SJAG_04598","SJAG_00192","SJAG_00899","SJAG_04618","SJAG_04938","SJAG_03270","SJAG_00092","SJAG_03558","SJAG_02234","SJAG_03810","SJAG_00858","SJAG_04391","SJAG_02012","SJAG_01600","SJAG_04419","SJAG_04402","SJAG_04513","SJAG_02103","SJAG_04739","SJAG_04837","SJAG_03552","SJAG_04070","SJAG_02264","SJAG_03467","SJAG_01003","SJAG_02539","SJAG_04196","SJAG_02349","SJAG_05013","SJAG_00072","SJAG_02655","SJAG_04112","SJAG_00557","SJAG_02482","SJAG_02120","SJAG_01991","SJAG_01409","SJAG_04021","SJAG_03933","SJAG_01415","SJAG_00767","SJAG_05345","SJAG_02160","SJAG_03670","SJAG_04909","SJAG_04528","SJAG_00484","SJAG_01508","SJAG_00330","SJAG_02839","SJAG_05326","SJAG_03153","SJAG_01899","SJAG_02640","SJAG_03244","SJAG_05344","SJAG_04615","SJAG_01166","SJAG_04002","SJAG_04569","SJAG_04592","SJAG_00357","SJAG_00578","SJAG_00785","SJAG_04740","SJAG_02525","SJAG_01279","SJAG_01642","SJAG_00906","SJAG_01025","SJAG_03907"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[57829,59022,63654,66264,69502,70076,70504,70640,71031,71848,71906,72453,73237,73468,73552,73994,74136,74402,74615,74786,74957,75298,75975,76702,76809,77394,77779,78116,78477,78524,78556,78611,79048,79302,79634,87978,90922,91287,91866,92902,92988,93652,94786,95374,95814,97537,97685,98238,100124,100537,100867,101970,104397,106210,106627,106925,109297,110543,110636,112224,112482,114804,116182,116325,118614,118745],"is_not":false,"summary":null,"term":"GO:0006888"},{"annotations":[72753],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0090114"},{"annotations":[71092,76790,78137,76249,75278,74508,74863],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0090110"},{"annotations":[76347],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0060628"}]},"cv_name":"biological_process","definition":"The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.","definition_xrefs":["ISBN:0716731363","GOC:ascb_2009","GOC:dph","GOC:jp","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular transport","termid":"GO:0046907"},{"relation_name":"is_a","term_name":"Golgi vesicle transport","termid":"GO:0048193"}],"gene_count":75,"genes_by_uniquename":{"SJAG_00072":null,"SJAG_00092":null,"SJAG_00192":null,"SJAG_00330":null,"SJAG_00357":null,"SJAG_00484":null,"SJAG_00557":null,"SJAG_00578":null,"SJAG_00767":null,"SJAG_00785":null,"SJAG_00858":null,"SJAG_00899":null,"SJAG_00906":null,"SJAG_01003":null,"SJAG_01025":null,"SJAG_01166":null,"SJAG_01279":null,"SJAG_01409":null,"SJAG_01415":null,"SJAG_01508":null,"SJAG_01600":null,"SJAG_01633":null,"SJAG_01642":null,"SJAG_01899":null,"SJAG_01991":null,"SJAG_02012":null,"SJAG_02103":null,"SJAG_02120":null,"SJAG_02160":null,"SJAG_02234":null,"SJAG_02264":null,"SJAG_02349":null,"SJAG_02482":null,"SJAG_02525":null,"SJAG_02539":null,"SJAG_02640":null,"SJAG_02655":null,"SJAG_02824":null,"SJAG_02839":null,"SJAG_03153":null,"SJAG_03244":null,"SJAG_03270":null,"SJAG_03467":null,"SJAG_03499":null,"SJAG_03552":null,"SJAG_03558":null,"SJAG_03670":null,"SJAG_03810":null,"SJAG_03907":null,"SJAG_03933":null,"SJAG_04002":null,"SJAG_04021":null,"SJAG_04070":null,"SJAG_04112":null,"SJAG_04196":null,"SJAG_04391":null,"SJAG_04402":null,"SJAG_04419":null,"SJAG_04434":null,"SJAG_04513":null,"SJAG_04528":null,"SJAG_04569":null,"SJAG_04592":null,"SJAG_04598":null,"SJAG_04615":null,"SJAG_04618":null,"SJAG_04739":null,"SJAG_04740":null,"SJAG_04837":null,"SJAG_04909":null,"SJAG_04938":null,"SJAG_05013":null,"SJAG_05326":null,"SJAG_05344":null,"SJAG_05345":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0016192","GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"endoplasmic reticulum to Golgi vesicle-mediated transport","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-199977","Reactome:R-HSA-159763","GO:0048221"],"synonyms":[{"name":"ER to Golgi transport","type":"exact"},{"name":"ER to Golgi vesicle-mediated transport","type":"exact"},{"name":"anterograde (ER to Golgi) transport","type":"exact"},{"name":"anterograde transport, ER to Golgi","type":"exact"},{"name":"anterograde transport, endoplasmic reticulum to Golgi","type":"exact"},{"name":"anterograde vesicle-mediated transport, ER to Golgi","type":"exact"},{"name":"anterograde vesicle-mediated transport, endoplasmic reticulum to Golgi","type":"exact"},{"name":"endoplasmic reticulum to Golgi transport","type":"exact"},{"name":"rough ER to cis-Golgi transport","type":"exact"},{"name":"rough ER to cis-Golgi vesicle-mediated transport","type":"exact"},{"name":"rough endoplasmic reticulum to cis-Golgi transport","type":"exact"},{"name":"rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport","type":"exact"}],"termid":"GO:0006888","terms_by_termid":{"GO:0006888":null,"GO:0060628":null,"GO:0090110":null,"GO:0090114":null}}


id: MONDO:0019014
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete mutilating palmoplantar keratoderma with periorificial keratotic plaques (obsolete MONDO:0019014)","termid":"MONDO:0019014","xrefs":{"Monarch":{"xref_id":"0019014"}}}


id: MONDO:1010124
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autoimmune lymphoproliferative syndrome that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune system disorder, non-human animal","termid":"MONDO:0700106"},{"relation_name":"is_a","term_name":"cancer or benign tumor, non-human animal","termid":"MONDO:1011305"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"syndromic disease, non-human animal","termid":"MONDO:1011360"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autoimmune lymphoproliferative syndrome, non-human animal","secondary_identifiers":["OMIA:002064"],"termid":"MONDO:1010124","xrefs":{"Monarch":{"xref_id":"1010124"}}}


id: FYPO:0004579
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from transposable element transcripts measured in a cell normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA level during vegetative growth","termid":"FYPO:0001317"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001312","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal transposable element-derived small RNA level","synonyms":[{"name":"normal transposable element-derived small RNA accumulation","type":"related"},{"name":"normal transposable element-derived small RNA level during mitotic cell cycle","type":"related"},{"name":"normal transposable element-derived small RNA level during vegetative growth","type":"exact"},{"name":"normal transposable element-derived small RNA transcript level","type":"exact"}],"termid":"FYPO:0004579"}


id: PBO:0070929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L17 pseudogene 37","termid":"PBO:0070929"}


id: PBO:0058468
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5197","termid":"PBO:0058468"}


id: GO:0036402
data:
  {"annotated_genes":["SJAG_01544","SJAG_01489","SJAG_04477","SJAG_01131","SJAG_00712","SJAG_00766"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73356,76831,77870,78021,78920,79207],"is_not":false,"summary":null,"term":"GO:0036402"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.","definition_xrefs":["PMID:11430818","GOC:rb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ATP-dependent activity","termid":"GO:0140657"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00712":null,"SJAG_00766":null,"SJAG_01131":null,"SJAG_01489":null,"SJAG_01544":null,"SJAG_04477":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674"],"is_obsolete":false,"name":"proteasome-activating activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["EC:5.6.1.5"],"synonyms":[{"name":"ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"proteasomal ATPase activity","type":"exact"},{"name":"proteasome channel gating activity","type":"narrow"},{"name":"proteasome channel opening activity","type":"narrow"},{"name":"proteasome-activating ATPase activity","type":"exact"}],"termid":"GO:0036402","terms_by_termid":{"GO:0036402":null}}


id: GO:0047002
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-arabinitol + NAD+ = L-ribulose + H+ + NADH.","definition_xrefs":["RHEA:21356","EC:1.1.1.13"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"L-arabinitol 2-dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R02441","MetaCyc:1.1.1.13-RXN"],"synonyms":[{"name":"L-arabinitol 2-dehydrogenase (ribulose forming) activity","type":"exact"}],"termid":"GO:0047002"}


id: MONDO:0859184
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ventriculomegaly and arthrogryposis","secondary_identifiers":["MEDGEN:1794183","OMIM:619501","UMLS:C5561973"],"termid":"MONDO:0859184","xrefs":{"Monarch":{"xref_id":"0859184"}}}


id: PBO:0038507
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP binding cassette subfamily D member 1 pseudogene 2","termid":"PBO:0038507"}


id: GO:0102074
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: OPC6-3-hydroxyacyl-CoA = OPC6-trans-2-enoyl-CoA + H2O.","definition_xrefs":["GOC:pz","EC:4.2.1.17"],"gene_count":0,"genotype_count":0,"name":"obsolete OPC6-trans-2-enoyl-CoA hydratase activity (obsolete GO:0102074)","termid":"GO:0102074"}


id: MONDO:0023538
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hypopituitarism","termid":"MONDO:0005152"},{"relation_name":"is_a","term_name":"microphthalmia","termid":"MONDO:0021129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"Kaplowitz-Bodurtha syndrome","secondary_identifiers":["MEDGEN:444037","MESH:C536893","UMLS:C2931361"],"synonyms":[{"name":"congenital hypopituitarism and microphthalmia","type":"related"},{"name":"hypopituitarism microphthalmia","type":"related"}],"termid":"MONDO:0023538","xrefs":{"Monarch":{"xref_id":"0023538"}}}


id: GO:0001818
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the rate of production of a cytokine.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine production","termid":"GO:0001817"},{"relation_name":"is_a","term_name":"negative regulation of gene expression","termid":"GO:0010629"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"negatively_regulates","term_name":"cytokine production","termid":"GO:0001816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of cytokine production","secondary_identifiers":["GO:0042036","GO:0050710"],"synonyms":[{"name":"down regulation of cytokine biosynthetic process","type":"exact"},{"name":"down regulation of cytokine production","type":"exact"},{"name":"down-regulation of cytokine biosynthetic process","type":"exact"},{"name":"down-regulation of cytokine production","type":"exact"},{"name":"downregulation of cytokine biosynthetic process","type":"exact"},{"name":"downregulation of cytokine production","type":"exact"},{"name":"inhibition of cytokine biosynthetic process","type":"narrow"},{"name":"inhibition of cytokine production","type":"narrow"},{"name":"negative regulation of cytokine anabolism","type":"exact"},{"name":"negative regulation of cytokine biosynthesis","type":"exact"},{"name":"negative regulation of cytokine biosynthetic process","type":"narrow"},{"name":"negative regulation of cytokine formation","type":"exact"},{"name":"negative regulation of cytokine secretion","type":"narrow"},{"name":"negative regulation of cytokine synthesis","type":"exact"}],"termid":"GO:0001818"}


id: GO:0008521
data:
  {"annotated_genes":["SJAG_04325"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[59391],"is_not":false,"summary":null,"term":"GO:0008521"}]},"cv_name":"molecular_function","definition":"Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic anion transmembrane transporter activity","termid":"GO:0008514"},{"relation_name":"is_a","term_name":"organophosphate ester transmembrane transporter activity","termid":"GO:0015605"},{"relation_name":"is_a","term_name":"nucleobase-containing compound transmembrane transporter activity","termid":"GO:0015932"},{"relation_name":"is_a","term_name":"amide transmembrane transporter activity","termid":"GO:0042887"},{"relation_name":"is_a","term_name":"sulfur compound transmembrane transporter activity","termid":"GO:1901682"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04325":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"acetyl-CoA transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000002":null},"secondary_identifiers":["Reactome:R-HSA-5649742","Reactome:R-HSA-727759"],"synonyms":[{"name":"acetyl-CoA transporter activity","type":"related"}],"termid":"GO:0008521","terms_by_termid":{"GO:0008521":null}}


id: MOD:00379
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-serine residue to L-serine microcin E492 siderophore ester.","definition_xrefs":["RESID:AA0374","PubMed:15102848","Unimod:448#C-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-serine residue","termid":"MOD:00916"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-serine microcin E492 siderophore ester","synonyms":[{"name":"L-serine microcin E492 siderophore ester","type":"exact"},{"name":"MOD_RES Serine microcin E492 siderophore ester","type":"exact"},{"name":"Microcin","type":"related"},{"name":"N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine","type":"exact"},{"name":"microcin E492 siderophore ester from serine","type":"related"}],"termid":"MOD:00379"}


id: GO:2001022
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.","definition_xrefs":["GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of response to DNA damage stimulus (obsolete GO:2001022)","synonyms":[{"name":"positive regulation of DNA damage response","type":"exact"},{"name":"positive regulation of cellular DNA damage response","type":"exact"},{"name":"positive regulation of cellular response to DNA damage stimulus","type":"exact"},{"name":"positive regulation of response to genotoxic stress","type":"exact"}],"termid":"GO:2001022"}


id: PBO:0089375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MICOS complex subunit Mic10","termid":"PBO:0089375"}


id: GO:0102935
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete gypsogenin-UDP-glucosyltransferase activity (obsolete GO:0102935)","termid":"GO:0102935"}


id: PBO:0040498
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aurora kinase A interacting protein 1","termid":"PBO:0040498"}


id: PBO:0028707
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_number_of_double-strand_break_sites_during_meiotic_cell_cycle","termid":"PBO:0028707"}


id: PBO:0108705
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RanGAP Hba1","termid":"PBO:0108705"}


id: PBO:0091178
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial methionine-tRNA ligase Msm1","termid":"PBO:0091178"}


id: PBO:0051736
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"INTS6 antisense RNA 1","termid":"PBO:0051736"}


id: GO:0030318
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pigment cell differentiation","termid":"GO:0050931"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"melanocyte differentiation","synonyms":[{"name":"melanocyte cell differentiation","type":"exact"},{"name":"melanophore differentiation","type":"exact"}],"termid":"GO:0030318"}


id: GO:1900162
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of phospholipid scramblase activity (obsolete GO:1900162)","synonyms":[{"name":"down regulation of phospholipid scramblase activity","type":"exact"},{"name":"down-regulation of phospholipid scramblase activity","type":"exact"},{"name":"downregulation of phospholipid scramblase activity","type":"exact"},{"name":"inhibition of phospholipid scramblase activity","type":"narrow"}],"termid":"GO:1900162"}


id: GO:0014076
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.","definition_xrefs":["GOC:ef","GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to antidepressant","termid":"GO:0036276"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to fluoxetine","synonyms":[{"name":"response to SSRI","type":"related"},{"name":"response to selective serotonin reuptake inhibitor","type":"related"}],"termid":"GO:0014076"}


id: GO:0097603
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).","definition_xrefs":["GOC:pr","GOC:ha","PMID:23027824"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monoatomic ion channel activity","termid":"GO:0005216"},{"relation_name":"is_a","term_name":"gated channel activity","termid":"GO:0022836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"temperature-gated ion channel activity","synonyms":[{"name":"heat-activated ion channel activity","type":"narrow"},{"name":"temperature gated ion channel activity","type":"exact"},{"name":"temperature-activated ion channel activity","type":"exact"},{"name":"temperature-dependent ion channel activity","type":"exact"}],"termid":"GO:0097603"}


id: MONDO:0015858
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare non-malformative breast disease (obsolete MONDO:0015858)","secondary_identifiers":["Orphanet:180202"],"termid":"MONDO:0015858","xrefs":{"Monarch":{"xref_id":"0015858"}}}


id: GO:0080049
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.","definition_xrefs":["RHEA:47248","PMID:18190525","PMID:30112455"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor","termid":"GO:0016632"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"L-gulono-1,4-lactone dehydrogenase activity","secondary_identifiers":["MetaCyc:RXN-1439"],"termid":"GO:0080049"}


id: PBO:0083287
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance","termid":"PBO:0083287"}


id: PBO:0067269
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 343, pseudogene","termid":"PBO:0067269"}


id: PBO:0074663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 50C","termid":"PBO:0074663"}


id: PBO:0001981
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III complex subunit Rpc82 (predicted)","termid":"PBO:0001981"}


id: MONDO:1010279
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hymen, imperforate that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"reproductive system disorder, non-human animal","termid":"MONDO:1011354"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hymen, imperforate, non-human animal","secondary_identifiers":["OMIA:001107"],"termid":"MONDO:1010279","xrefs":{"Monarch":{"xref_id":"1010279"}}}


id: GO:0035244
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein. This modification has been detected in anaerobic bacteria.","definition_xrefs":["PMID:33162960","PMID:29743535","GOC:bf","RHEA:66028"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C-methyltransferase activity","termid":"GO:0008169"},{"relation_name":"is_a","term_name":"protein methyltransferase activity","termid":"GO:0008276"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140096","GO:0008276","GO:0016740","GO:0003674","GO:0016741","GO:0003824"],"is_obsolete":false,"name":"protein-arginine C-methyltransferase activity","secondary_identifiers":["EC:2.1.1.379"],"synonyms":[{"name":"peptidyl arginine C-methyltransferase activity","type":"exact"},{"name":"peptidyl-arginine C-methylase activity","type":"exact"},{"name":"peptidyl-arginine C-methyltransferase activity","type":"exact"},{"name":"protein-arginine C-methylase activity","type":"exact"}],"termid":"GO:0035244"}


id: PATO:0000696
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000696 texture value (obsolete PATO:0000696)","termid":"PATO:0000696"}


id: PBO:0047619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FIG4 phosphoinositide 5-phosphatase","termid":"PBO:0047619"}


id: MONDO:0013915
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypogonadotropic hypogonadism in which the cause of the disease is a mutation in the KISS1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypogonadotropic hypogonadism","termid":"MONDO:0018555"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypogonadotropic hypogonadism 13 with or without anosmia","secondary_identifiers":["DOID:0090073","GARD:18601","MEDGEN:762090","OMIM:614842","ICD10CM:E23.0","UMLS:C3541462"],"synonyms":[{"name":"HH13","type":"related"},{"name":"KISS1 hypogonadotropic hypogonadism","type":"exact"},{"name":"hypogonadotropic hypogonadism 13 with or without anosmia","type":"exact"},{"name":"hypogonadotropic hypogonadism caused by mutation in KISS1","type":"exact"}],"termid":"MONDO:0013915","xrefs":{"Monarch":{"xref_id":"0013915"}}}


id: PBO:0111832
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zf-C5HC2 type","termid":"PBO:0111832"}


id: MONDO:0009831
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the pancreas.","direct_ancestors":[{"relation_name":"is_a","term_name":"digestive system cancer","termid":"MONDO:0002516"},{"relation_name":"is_a","term_name":"pancreatic neoplasm","termid":"MONDO:0021040"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"malignant pancreatic neoplasm","secondary_identifiers":["ICD9:157.1","ICD9:157.8","DOID:1793","ICD9:157.0","NCIT:C9005","EFO:1000359","ICD9:157.2"],"synonyms":[{"name":"Ca body of pancreas","type":"exact"},{"name":"Ca head of pancreas","type":"exact"},{"name":"Ca tail of pancreas","type":"exact"},{"name":"cancer of pancreas","type":"exact"},{"name":"malignant neoplasm of body of pancreas","type":"exact"},{"name":"malignant neoplasm of head of pancreas","type":"exact"},{"name":"malignant neoplasm of pancreas","type":"exact"},{"name":"malignant neoplasm of tail of pancreas","type":"exact"},{"name":"malignant neoplasm of the pancreas","type":"exact"},{"name":"malignant pancreas neoplasm","type":"exact"},{"name":"malignant pancreatic neoplasm","type":"exact"},{"name":"pancreas cancer","type":"exact"},{"name":"pancreas neoplasm","type":"broad"},{"name":"pancreatic cancer","type":"exact"},{"name":"pancreatic tumour","type":"related"}],"termid":"MONDO:0009831","xrefs":{"Monarch":{"xref_id":"0009831"}}}


id: PBO:0090014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein GPR107/GPR108-like","termid":"PBO:0090014"}


id: GO:0001763
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"is_a","term_name":"multicellular organismal process","termid":"GO:0032501"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"morphogenesis of a branching structure","synonyms":[{"name":"branching morphogenesis","type":"exact"}],"termid":"GO:0001763"}


id: PBO:0079837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UNC5B antisense RNA 1","termid":"PBO:0079837"}


id: MONDO:0032767
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"paraganglioma","termid":"MONDO:0000448"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paragangliomas 6","secondary_identifiers":["MEDGEN:1681559","OMIM:618464","UMLS:C5193112","GARD:16354"],"synonyms":[{"name":"PARAGANGLIOMAS 6","type":"related"},{"name":"PGL6","type":"related"}],"termid":"MONDO:0032767","xrefs":{"Monarch":{"xref_id":"0032767"}}}


id: GO:1900374
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching.","definition_xrefs":["GOC:TermGenie","PMID:8804308","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter (obsolete GO:1900374)","synonyms":[{"name":"activation of mating type switching by regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"stimulation of mating type switching by regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"up regulation of mating type switching by regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"up-regulation of mating type switching by regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"upregulation of mating type switching by regulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:1900374"}


id: FYECO:0000045
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which pentadecanoic acid was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ fatty acid","termid":"FYECO:0000042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ pentadecanoic acid","termid":"FYECO:0000045"}


id: FYPO:0000143
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A gene expression phenotype that affects the regulation of DNA-dependent transcription.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression regulation phenotype","termid":"FYPO:0000288"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002"],"is_obsolete":false,"name":"transcription regulation phenotype","synonyms":[{"name":"fission yeast transcription regulation phenotype","type":"exact"},{"name":"gene-specific transcription regulation phenotype","type":"related"},{"name":"transcriptional control phenotype","type":"broad"}],"termid":"FYPO:0000143"}


id: GO:0039015
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell proliferation involved in kidney development","termid":"GO:0072111"},{"relation_name":"part_of","term_name":"pronephros development","termid":"GO:0048793"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell proliferation involved in pronephros development","synonyms":[{"name":"cell proliferation involved in pronephric kidney development","type":"exact"}],"termid":"GO:0039015"}


id: PBO:0034356
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_homeosis_relationship_with","termid":"PBO:0034356"}


id: GO:0016648
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors","termid":"GO:0016645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor","secondary_identifiers":["EC:1.5.4.-"],"synonyms":[{"name":"oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor","type":"exact"}],"termid":"GO:0016648"}


id: PBO:0083954
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Gamma-tubulin small complex (gamma-TuSC) receptor; recruits the gamma-TuSC complex to the cytoplasmic side of the SPB, connecting nuclear microtubules to the SPB; involved in astral microtubule formation, stabilization, and with Stu2p, anchoring astral MTs at the cytoplasmic face of the SPB, and regulating plus-end MT dynamics; regulated by Cdc5 kinase","termid":"PBO:0083954"}


id: PBO:0072235
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S20 pseudogene 10","termid":"PBO:0072235"}


id: PBO:0003062
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.4.8","termid":"PBO:0003062"}


id: MONDO:0005198
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Intraepithelial neoplasia of the vulvar squamous epithelium. There is no evidence of invasion. This category includes vulvar high grade squamous intraepithelial lesion and vulvar intraepithelial neoplasia, differentiated type.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vulvar squamous neoplasm","termid":"MONDO:0002195"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vulvar intraepithelial neoplasia","secondary_identifiers":["NCIT:C4756","EFO:0002627","UMLS:C0346210","GARD:19876","MEDGEN:91093","Orphanet:137583"],"synonyms":[{"name":"VIN","type":"exact"},{"name":"intraepithelial neoplasia of the vulva","type":"exact"},{"name":"intraepithelial neoplasia of vulva","type":"exact"},{"name":"squamous vulvar intraepithelial neoplasia","type":"exact"},{"name":"vulva intraepithelial neoplasia","type":"exact"},{"name":"vulval intraepithelial neoplasia","type":"exact"},{"name":"vulvar intraepithelial tumor","type":"exact"},{"name":"vulvar intraepithelial tumour","type":"exact"}],"termid":"MONDO:0005198","xrefs":{"Monarch":{"xref_id":"0005198"}}}


id: GO:0042962
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).","definition_xrefs":["PMID:10735876"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proton transmembrane transporter activity","termid":"GO:0015078"},{"relation_name":"is_a","term_name":"antiporter activity","termid":"GO:0015297"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"acridine:proton antiporter activity","synonyms":[{"name":"acridine efflux pump activity","type":"related"},{"name":"acridine:hydrogen antiporter activity","type":"exact"}],"termid":"GO:0042962"}


id: GO:0047008
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NADP+ + pregnan-21-ol = H+ + NADPH + pregnan-21-al.","definition_xrefs":["RHEA:23712"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0033764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"pregnan-21-ol dehydrogenase (NADP+) activity","secondary_identifiers":["KEGG_REACTION:R03044","MetaCyc:1.1.1.151-RXN","EC:1.1.1.151"],"synonyms":[{"name":"21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity","type":"broad"},{"name":"21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity","type":"broad"},{"name":"21-hydroxy steroid dehydrogenase activity","type":"broad"},{"name":"21-hydroxysteroid dehydrogenase (NADP+) activity","type":"broad"},{"name":"21-hydroxysteroid:NADP+ 21-oxidoreductase activity","type":"broad"},{"name":"NADP-21-hydroxysteroid dehydrogenase activity","type":"broad"}],"termid":"GO:0047008"}


id: PBO:0047130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 170 member B","termid":"PBO:0047130"}


id: PBO:0087068
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L33B; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33B has a paralog, RPL33A, that arose from the whole genome duplication","termid":"PBO:0087068"}


id: PBO:0000893
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TATA-binding protein (predicted)","termid":"PBO:0000893"}


id: PBO:0005121
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab GTPase binding involved in ER to Golgi vesicle transport (predicted)","termid":"PBO:0005121"}


id: PBO:0010136
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADHX dehydratase (predicted)","termid":"PBO:0010136"}


id: FYPO:0004413
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a phosphatase activity is decreased during a cellular response to phosphate starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased phosphatase activity","termid":"FYPO:0004304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000661","FYPO:0000707","FYPO:0000652","FYPO:0000654"],"is_obsolete":false,"name":"decreased phosphatase activity during cellular response to phosphate starvation","synonyms":[{"name":"decreased phosphatase activity during phosphate starvation","type":"exact"},{"name":"reduced phosphatase activity during cellular response to phosphate starvation","type":"exact"}],"termid":"FYPO:0004413"}


id: GO:0047728
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.","definition_xrefs":["EC:1.1.1.108","RHEA:19265"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"carnitine 3-dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R02395","MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN"],"synonyms":[{"name":"carnitine:NAD+ 3-oxidoreductase activity","type":"related"}],"termid":"GO:0047728"}


id: GO:0140107
data:
  {"annotated_genes":["SJAG_02883","SJAG_01353"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70221,72019],"is_not":false,"summary":null,"term":"GO:0140107"}]},"cv_name":"molecular_function","definition":"Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.","definition_xrefs":["PMID:10629185"],"direct_ancestors":[{"relation_name":"is_a","term_name":"potassium ion transmembrane transporter activity","termid":"GO:0015079"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01353":null,"SJAG_02883":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"high-affinity potassium ion transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0140107","terms_by_termid":{"GO:0140107":null}}


id: MONDO:0100256
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Germline pathogenic or likely pathogenic variants in the CTNNA1 gene predispose to hereditary diffuse gastric cancer and lobular breast cancer, a cancer susceptibility syndrome inherited in an autosomal dominant pattern.","direct_ancestors":[{"relation_name":"is_a","term_name":"breast lobular carcinoma","termid":"MONDO:0000552"},{"relation_name":"is_a","term_name":"gastric adenocarcinoma","termid":"MONDO:0005036"},{"relation_name":"is_a","term_name":"hereditary breast carcinoma","termid":"MONDO:0016419"},{"relation_name":"is_a","term_name":"hereditary gastric cancer","termid":"MONDO:0018502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"CTNNA1-related diffuse gastric and lobular breast cancer syndrome","termid":"MONDO:0100256","xrefs":{"Monarch":{"xref_id":"0100256"}}}


id: MONDO:0008606
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Say-Field-Coldwell syndrome is characterized by triphalangeal thumbs, brachydactyly, camptodactyly, recurrent dislocation of the patellas and relatively short stature. It has been described in a mother and her three daughters.","definition_xrefs":["Orphanet:3133"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital limb malformation","termid":"MONDO:0019054"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Say-field-Coldwell syndrome","secondary_identifiers":["GARD:242","MEDGEN:348711","MESH:C536619","OMIM:190650","UMLS:C1860805"],"synonyms":[{"name":"polydactyly with triphalangeal thumbs, brachydactyly, camptodactyly, congenital dislocation of the patellas, short stature and borderline intelligence","type":"related"},{"name":"triphalangeal thumbs and dislocation of patella","type":"related"},{"name":"triphalangeal thumbs-dislocation of patella syndrome","type":"exact"}],"termid":"MONDO:0008606","xrefs":{"Monarch":{"xref_id":"0008606"}}}


id: MONDO:0003045
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Tumors or cancer of the anal gland.","definition_xrefs":["MESH:D000694"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anus neoplasm","termid":"MONDO:0003046"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"anal gland neoplasm","secondary_identifiers":["MEDGEN:1897","UMLS:C0002757","DOID:4550"],"synonyms":[{"name":"gland of anal canal neoplasm","type":"exact"},{"name":"gland of anal canal neoplasm (disease)","type":"exact"},{"name":"gland of anal canal tumor","type":"exact"},{"name":"gland of anal canal tumour","type":"exact"},{"name":"neoplasm of gland of anal canal","type":"exact"},{"name":"tumor of gland of anal canal","type":"exact"},{"name":"tumour of gland of anal canal","type":"exact"}],"termid":"MONDO:0003045","xrefs":{"Monarch":{"xref_id":"0003045"}}}


id: FYPO:0006594
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which localization of the gamma-tubulin complex to the spindle pole body is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization during vegetative growth","termid":"FYPO:0000644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001320","FYPO:0000257","FYPO:0000002","FYPO:0001312"],"is_obsolete":false,"name":"normal gamma-tubulin complex localization to mitotic spindle pole body","synonyms":[{"name":"normal gamma-tubulin complex localisation to mitotic spindle pole body","type":"exact"},{"name":"normal gamma-tubulin complex localization to mitotic SPB","type":"exact"},{"name":"normal gamma-tubulin complex localization to mitotic spindle pole body during vegetative growth","type":"exact"},{"name":"normal gamma-tubulin complex localization to spindle pole body during mitotic cell cycle","type":"related"}],"termid":"FYPO:0006594"}


id: GO:0032235
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.","definition_xrefs":["PMID:16582901","GOC:bf"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of calcium ion transport via store-operated calcium channel activity (obsolete GO:0032235)","synonyms":[{"name":"down regulation of calcium ion transport via store-operated calcium channel","type":"exact"},{"name":"down-regulation of calcium ion transport via store-operated calcium channel","type":"exact"},{"name":"downregulation of calcium ion transport via store-operated calcium channel","type":"exact"},{"name":"inhibition of calcium ion transport via store-operated calcium channel","type":"narrow"},{"name":"negative regulation of calcium ion transport via store-operated calcium channel activity","type":"exact"},{"name":"negative regulation of calcium transport via store-operated calcium channel","type":"exact"},{"name":"negative regulation of store-operated calcium channel activity","type":"exact"}],"termid":"GO:0032235"}


id: MONDO:0005950
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Poisoning caused by ingestion of food harboring species of salmonella. Conditions of raising, shipping, slaughtering, and marketing of domestic animals contribute to the spread of this bacterium in the food supply.","definition_xrefs":["MESH:D012478"],"direct_ancestors":[{"relation_name":"is_a","term_name":"salmonellosis","termid":"MONDO:0000827"},{"relation_name":"is_a","term_name":"gastroenteritis","termid":"MONDO:0002269"},{"relation_name":"is_a","term_name":"digestive system infectious disorder","termid":"MONDO:0043424"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"Salmonella gastroenteritis","secondary_identifiers":["SCTID:42338000","EFO:0007475","MEDGEN:48541","UMLS:C0036114","ICD9:003.0"],"synonyms":[{"name":"Salmonella caused gastroenteritis","type":"exact"}],"termid":"MONDO:0005950","xrefs":{"Monarch":{"xref_id":"0005950"}}}


id: PBO:0053024
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine aminopeptidase 3","termid":"PBO:0053024"}


id: GO:0038007
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by the binding of a netrin protein to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.","definition_xrefs":["PMID:15960985","PMID:10399919","PMID:19785719","GOC:signaling","PMID:20108323"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell surface receptor signaling pathway","termid":"GO:0007166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"netrin-activated signaling pathway","synonyms":[{"name":"netrin signaling pathway","type":"exact"},{"name":"netrin-activated signal transduction pathway","type":"exact"},{"name":"netrin-activated signalling pathway","type":"exact"},{"name":"netrin-mediated signaling pathway","type":"exact"}],"termid":"GO:0038007"}


id: MONDO:0020790
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"horizontal gaze palsy with progressive scoliosis","termid":"MONDO:0011810"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gaze palsy, familial horizontal, with progressive scoliosis 1","secondary_identifiers":["UMLS:C4551964","MEDGEN:1647423","OMIM:607313"],"synonyms":[{"name":"HGPPS","type":"exact"},{"name":"HGPPS1","type":"exact"},{"name":"Ophthalmoplegia, Progressive External, and Scoliosis","type":"related"},{"name":"gaze palsy, familial horizontal, with progressive scoliosis 1","type":"exact"},{"name":"gaze palsy, familial horizontal, with progressive scoliosis, 1","type":"exact"}],"termid":"MONDO:0020790","xrefs":{"Monarch":{"xref_id":"0020790"}}}


id: GO:0061046
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.","definition_xrefs":["GOC:yaf","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of morphogenesis of a branching structure","termid":"GO:0060688"},{"relation_name":"is_a","term_name":"regulation of morphogenesis of an epithelium","termid":"GO:1905330"},{"relation_name":"regulates","term_name":"epithelial tube branching involved in lung morphogenesis","termid":"GO:0060441"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of branching involved in lung morphogenesis","termid":"GO:0061046"}


id: MONDO:0019472
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Extranodal nasal NK/T cell lymphoma (NKTCL) is a rare, malignant neoplasm mainly affecting men in the fifth decade of life, that usually arises in the nose, paranasal sinuses, orbits or upper airway, and that can present with a nasal mass, nasal bleeding, nasal obstruction, palate perforation (i.e. midline perforation of the hard palate), and mid-facial and/or upper airway destructive lesions. In advanced disease stages, which are associated with a poor prognosis, NKTCL may disseminate to other organs. A few cases of NKTCL presenting primarily in the lymph nodes have also been described.","definition_xrefs":["Orphanet:86879"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lymphoma","termid":"MONDO:0005062"},{"relation_name":"is_a","term_name":"Epstein-Barr virus-associated malignant lymphoproliferative disorder","termid":"MONDO:0017343"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"extranodal nasal NK/T cell lymphoma","secondary_identifiers":["MedDRA:10065855","DOID:0080797","GARD:7041","NANDO:2200027","UMLS:C0392788","NCIT:C4684","ICDO:9719/3","icd11.foundation:684005900","MEDGEN:140278"],"synonyms":[{"name":"Extranodal NK/T lymphoma-nasal","type":"exact"},{"name":"Extranodal NK/T-cell lymphoma, nasal type","type":"exact"},{"name":"NK/T-cell lymphoma","type":"exact"},{"name":"NKTCL","type":"exact"},{"name":"angiocentric T-cell lymphoma","type":"exact"},{"name":"lethal midline granuloma","type":"exact"},{"name":"nasal T/natural killer-cell lymphoma","type":"exact"},{"name":"nasal type Extranodal NK/T-cell lymphoma","type":"exact"},{"name":"reticulosis, malignant","type":"exact"}],"termid":"MONDO:0019472","xrefs":{"Monarch":{"xref_id":"0019472"}}}


id: PR:Q09869
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A transcription initiation factor TFIID subunit 9 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR12075:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription initiation factor TFIID subunit 9 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC12G12.05c","secondary_identifiers":["UniProtKB:Q09869"],"synonyms":[{"name":"SPAC12G12.05c","type":"related"},{"name":"Spom972h-TAF9","type":"exact"},{"name":"TBP-associated factor 9 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q09869"}


id: SO:0001412
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A DNA region within which self-interaction occurs more often than expected by chance because of DNA-looping.","definition_xrefs":["SO:cb","PMID:32782014"],"direct_ancestors":[{"relation_name":"is_a","term_name":"region","termid":"SO:0000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"topologically_defined_region","synonyms":[{"name":"topologically defined region","type":"exact"}],"termid":"SO:0001412"}


id: FYPO:0008139
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the endoplasmic reticulum lumen is larger than normal.","definition_xrefs":["PMID:11839792"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal endoplasmic reticulum morphology","termid":"FYPO:0000354"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"dilated endoplasmic reticulum lumen","synonyms":[{"name":"dialted ER lumen","type":"exact"}],"termid":"FYPO:0008139"}


id: PBO:0066022
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAN binding protein 3","termid":"PBO:0066022"}


id: GO:0051976
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.","definition_xrefs":["MetaCyc:PWY-3081"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lysine biosynthetic process via aminoadipic acid","termid":"GO:0019878"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate","synonyms":[{"name":"lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate","type":"exact"},{"name":"lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate","type":"exact"}],"termid":"GO:0051976"}


id: MONDO:0700208
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Caliciviridae infectious disease that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral infectious disease, non-human animal","termid":"MONDO:0700053"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Caliciviridae infectious disease, non-human animal","termid":"MONDO:0700208","xrefs":{"Monarch":{"xref_id":"0700208"}}}


id: PBO:0083107
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DnaJ-like chaperone required for nuclear membrane fusion during mating; localizes to the ER membrane; exhibits genetic interactions with KAR2","termid":"PBO:0083107"}


id: GO:0034378
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma lipoprotein particle assembly","termid":"GO:0034377"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0065003"],"is_obsolete":false,"name":"chylomicron assembly","secondary_identifiers":["Reactome:R-HSA-8963888"],"termid":"GO:0034378"}


id: FYPO:0001315
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cell morphology","termid":"FYPO:0000672"},{"relation_name":"is_a","term_name":"normal vegetative phenotype","termid":"FYPO:0001312"},{"relation_name":"is_a","term_name":"cellular physical quality phenotype during vegetative growth","termid":"FYPO:0001321"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0001312","FYPO:0000002"],"is_obsolete":false,"name":"normal vegetative cell morphology","synonyms":[{"name":"normal cell morphology during vegetative growth","type":"exact"},{"name":"normal vegetative cell morphology during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001315"}


id: PBO:0091558
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TetratricoPeptide Repeat","termid":"PBO:0091558"}


id: FYECO:0000331
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in medium containing glucose, salts, water and with arginine as the nitrogen source.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping defined medium","termid":"FYECO:0000013"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucose MM, arginine nitrogen source","synonyms":[{"name":"glucose minimal medium, arginine nitrogen source","type":"exact"}],"termid":"FYECO:0000331"}


id: PBO:0033774
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_maintenance_of_spindle_pole_body_localization","termid":"PBO:0033774"}


id: PBO:0114492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER-resident glycoprotein involved in high-pressure tolerance; proposed role promoting proper folding of nutrient permeases, such as Tat2p, in the ER during hydrostatic pressure stress and maintaining permease conformational stability; contains two transmembrane domains, a C-terminal cytoplasmic domain and a luminal region with 12 N-linked glycans; null is synthetically sick with cdc13-1; localizes to the ER membrane","termid":"PBO:0114492"}


id: MOD:01831
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-cysteine residue to S-carboxamidomethyl-L-cysteine sulfone.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"S-carboxamidomethyl-L-cysteine","termid":"MOD:01060"},{"relation_name":"is_a","term_name":"iodoacetamide derivatized residue","termid":"MOD:00397"},{"relation_name":"is_a","term_name":"sulfur oxygenated L-cysteine","termid":"MOD:00708"},{"relation_name":"is_a","term_name":"sulfur dioxygenated residue","termid":"MOD:01855"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"S-carboxamidomethyl-L-cysteine sulfone","synonyms":[{"name":"CamCO2","type":"exact"},{"name":"S-carbamoylmethyl-L-cysteine sulfone","type":"exact"}],"termid":"MOD:01831"}


id: MONDO:0016294
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hirschsprung disease-type D brachydactyly syndrome is characterized by Hirschsprung disease and absence or hypoplasia of the nails and distal phalanges of the thumbs and great toes (type D brachydactyly). It has been described in four males from one family (two brothers and two maternal uncles). Transmission appears to be X-linked recessive but autosomal dominant inheritance with incomplete penetrance in females can not be ruled out.","definition_xrefs":["Orphanet:2150"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"intestinal motility disease","termid":"MONDO:0021189"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"Hirschsprung disease-type D brachydactyly syndrome","secondary_identifiers":["MESH:C538319","OMIM:306980","GARD:2700","MEDGEN:375339","UMLS:C1844017"],"synonyms":[{"name":"Hirschsprung disease type d brachydactyly","type":"related"},{"name":"Hirschsprung disease with type D brachydactyly","type":"related"},{"name":"Hirschsprung disease with type d brachydactyly","type":"exact"},{"name":"familial Hirschsprung's disease and type D brachydactyly","type":"related"}],"termid":"MONDO:0016294","xrefs":{"Monarch":{"xref_id":"0016294"}}}


id: GO:0072596
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a protein to a specific location in a chloroplast.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of protein localization to organelle","termid":"GO:0072594"},{"relation_name":"is_a","term_name":"protein localization to chloroplast","termid":"GO:0072598"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"establishment of protein localization to chloroplast","synonyms":[{"name":"establishment of protein localisation to chloroplast","type":"exact"}],"termid":"GO:0072596"}


id: PBO:0090227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial threonine-tRNA ligase","termid":"PBO:0090227"}


id: GO:0097001
data:
  {"annotated_genes":["SJAG_03690"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[117328],"is_not":false,"summary":null,"term":"GO:0097001"}]},"cv_name":"molecular_function","definition":"Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.","definition_xrefs":["GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amide binding","termid":"GO:0033218"},{"relation_name":"is_a","term_name":"sphingolipid binding","termid":"GO:0046625"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03690":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008289"}],"interesting_parent_ids":["GO:0003674","GO:0008289","GO:0005488"],"is_obsolete":false,"name":"ceramide binding","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0097001","terms_by_termid":{"GO:0097001":null}}


id: PBO:0018126
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HD domain protein (predicted)","termid":"PBO:0018126"}


id: PBO:0002174
data:
  {"annotation_feature_type":"gene","cv_name":"sequence_feature","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein KEN box","termid":"PBO:0002174"}


id: PBO:0029544
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-viable_mixed_population_including_long_cells_(obsolete_FYPO:0002178)","termid":"PBO:0029544"}


id: PBO:0049796
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2","termid":"PBO:0049796"}


id: GO:0008763
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanine.","definition_xrefs":["EC:6.3.2.8","RHEA:23372"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acid-amino acid ligase activity","termid":"GO:0016881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016874"],"is_obsolete":false,"name":"UDP-N-acetylmuramate-L-alanine ligase activity","secondary_identifiers":["KEGG_REACTION:R03193","MetaCyc:UDP-NACMUR-ALA-LIG-RXN"],"synonyms":[{"name":"L-Ala ligase activity","type":"related"},{"name":"L-alanine-adding enzyme activity","type":"related"},{"name":"MurC synthetase activity","type":"narrow"},{"name":"UDP-MurNAc:L-alanine ligase activity","type":"related"},{"name":"UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)","type":"related"},{"name":"UDP-N-acetylmuramoyl-L-alanine synthetase activity","type":"related"},{"name":"UDP-N-acetylmuramoylalanine synthetase activity","type":"related"},{"name":"UDP-N-acetylmuramyl:L-alanine ligase activity","type":"related"},{"name":"UDP-acetylmuramyl-L-alanine synthetase activity","type":"related"},{"name":"UDPMurNAc-L-alanine synthetase activity","type":"related"},{"name":"alanine-adding enzyme activity","type":"related"},{"name":"uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity","type":"related"},{"name":"uridine diphosphate N-acetylmuramate:L-alanine ligase activity","type":"related"},{"name":"uridine diphospho-N-acetylmuramoylalanine synthetase activity","type":"related"},{"name":"uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity","type":"related"}],"termid":"GO:0008763"}


id: FYPO:0003161
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased RNA level during vegetative growth","termid":"FYPO:0001117"},{"relation_name":"is_a","term_name":"substance absent from cell during vegetative growth","termid":"FYPO:0001208"},{"relation_name":"is_a","term_name":"RNA absent from cell","termid":"FYPO:0001889"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0006551","FYPO:0005447"],"is_obsolete":false,"name":"RNA absent from cell during vegetative growth","secondary_identifiers":["FYPO:0004509"],"synonyms":[{"name":"RNA absent from cell during mitotic cell cycle","type":"related"},{"name":"mRNA absent from cell","type":"narrow"},{"name":"mRNA absent from cell during mitotic cell cycle","type":"related"},{"name":"mRNA absent from cell during vegetative growth","type":"narrow"},{"name":"mRNA transcripts absent from cell","type":"narrow"},{"name":"messenger RNA absent from cell","type":"narrow"},{"name":"transcripts absent from cell during vegetative growth","type":"exact"},{"name":"undetectable RNA level during vegetative growth","type":"exact"},{"name":"undetectable mRNA level","type":"narrow"}],"termid":"FYPO:0003161"}


id: PBO:0077023
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thioesterase superfamily member 5","termid":"PBO:0077023"}


id: PBO:0053194
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine zipper and EF-hand containing transmembrane protein 1 pseudogene 2","termid":"PBO:0053194"}


id: MONDO:0013276
data:
  {"annotated_genes":["SJAG_04810"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85938],"is_not":false,"summary":null,"term":"MONDO:0013276"}]},"cv_name":"mondo","definition":"An autoimmune disorder characterized by the association of primary biliary cirrhosis (PBC) with limited cutaneous systemic sclerosis (lcSSc).","definition_xrefs":["Orphanet:779"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete secondary glomerular disease (obsolete MONDO:0019724)","termid":"MONDO:0019724"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"autoimmune disease","termid":"MONDO:0007179"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04810":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"Reynolds syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1409844299","OMIM:613471","UMLS:C0748397","SCTID:715401008","MEDGEN:450547","GARD:4697"],"synonyms":[{"name":"Reynolds syndrome","type":"exact"},{"name":"primary biliary cirrhosis and systemic scleroderma","type":"exact"},{"name":"primary biliary cirrhosis, Scleroderma, Raynaud disease, and telangiectasia","type":"related"}],"termid":"MONDO:0013276","terms_by_termid":{"MONDO:0013276":null},"xrefs":{"Monarch":{"xref_id":"0013276"}}}


id: GO:0060701
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.","definition_xrefs":["GOC:tb","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of ribonuclease activity (obsolete GO:0060701)","termid":"GO:0060701"}


id: PBO:0047023
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 90 member A26","termid":"PBO:0047023"}


id: PBO:0059932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND2 pseudogene 18","termid":"PBO:0059932"}


id: GO:2001112
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular response to growth factor stimulus","termid":"GO:0090287"},{"relation_name":"regulates","term_name":"cellular response to hepatocyte growth factor stimulus","termid":"GO:0035729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cellular response to hepatocyte growth factor stimulus","synonyms":[{"name":"regulation of cellular response to HGF stimulus","type":"exact"}],"termid":"GO:2001112"}


id: GO:0009748
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals mediated by hexose and independent of hexokinase.","definition_xrefs":["GOC:mah","GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexose mediated signaling","termid":"GO:0009757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"hexokinase-independent signaling","synonyms":[{"name":"hexokinase-independent signalling","type":"exact"}],"termid":"GO:0009748"}


id: PBO:0059116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mov10 like RISC complex RNA helicase 1","termid":"PBO:0059116"}


id: GO:1904151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.","definition_xrefs":["PMID:19100238","GOC:TermGenie","GOC:BHF","GOC:nc","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of leukocyte mediated cytotoxicity","termid":"GO:0001912"},{"relation_name":"is_a","term_name":"positive regulation of myeloid leukocyte mediated immunity","termid":"GO:0002888"},{"relation_name":"is_a","term_name":"regulation of microglial cell mediated cytotoxicity","termid":"GO:1904149"},{"relation_name":"positively_regulates","term_name":"microglial cell mediated cytotoxicity","termid":"GO:0090634"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of microglial cell mediated cytotoxicity","synonyms":[{"name":"activation of microglial cell mediated cytotoxicity","type":"narrow"},{"name":"up regulation of microglial cell mediated cytotoxicity","type":"exact"},{"name":"up-regulation of microglial cell mediated cytotoxicity","type":"exact"},{"name":"upregulation of microglial cell mediated cytotoxicity","type":"exact"}],"termid":"GO:1904151"}


id: PBO:0077480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 200C","termid":"PBO:0077480"}


id: MONDO:0018526
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete serous cystadenocarcinoma of pancreas (obsolete MONDO:0018526)","termid":"MONDO:0018526","xrefs":{"Monarch":{"xref_id":"0018526"}}}


id: PR:O13750
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO01475","PANTHER:PTHR11117:SF3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"succinyl-CoA ligase [ADP-forming] subunit alpha, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC16E8.17c","secondary_identifiers":["UniProtKB:O13750"],"synonyms":[{"name":"SCS-alpha (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-SUCLG1","type":"exact"},{"name":"succinyl-CoA synthetase subunit alpha (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O13750"}


id: MONDO:0020617
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete blood group--ok (obsolete MONDO:0020617)","secondary_identifiers":["OMIM:111380"],"synonyms":[{"name":"BLOOD GROUP--OK","type":"related"},{"name":"OK","type":"related"},{"name":"blood group, OK","type":"exact"}],"termid":"MONDO:0020617","xrefs":{"Monarch":{"xref_id":"0020617"}}}


id: FYPO:0002586
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial tRNA 3'-end processing is normal (i.e. indistinguishable from wild type). In mitochondrial tRNA 3'-end processing, the 3' end of a mitochondrial pre-tRNA molecule is converted to that of a mature mitochondrial tRNA.","definition_xrefs":["GO:0006396","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA processing","termid":"FYPO:0001980"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0000002","FYPO:0001312"],"is_obsolete":false,"name":"normal mitochondrial tRNA 3'-end processing","synonyms":[{"name":"normal mitochondrial tRNA 3'-end processing during mitotic cell cycle","type":"related"},{"name":"normal mitochondrial tRNA 3'-end processing during vegetative growth","type":"exact"},{"name":"normal mitochondrial transfer RNA 3'-end processing","type":"exact"}],"termid":"FYPO:0002586"}


id: PBO:0018123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial guanine nucleotide transmembrane transporter Ggc1 (predicted)","termid":"PBO:0018123"}


id: GO:0045713
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete low-density lipoprotein particle receptor biosynthetic process (obsolete GO:0045713)","synonyms":[{"name":"LDLr biosynthesis","type":"exact"},{"name":"LDLr biosynthetic process","type":"exact"},{"name":"low-density lipoprotein receptor anabolism","type":"exact"},{"name":"low-density lipoprotein receptor biosynthesis","type":"exact"},{"name":"low-density lipoprotein receptor biosynthetic process","type":"exact"},{"name":"low-density lipoprotein receptor formation","type":"exact"},{"name":"low-density lipoprotein receptor synthesis","type":"exact"}],"termid":"GO:0045713"}


id: FYECO:0000111
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which myo-inositol was added to the medium or assay buffers in a limiting quantity compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping limited","termid":"FYECO:0000011"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ limited myo-inositol","secondary_identifiers":["PMID:9560432"],"synonyms":[{"name":"limited inositol added","type":"related"}],"termid":"FYECO:0000111"}


id: PBO:0084453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p; SUR1 has a paralog, CSH1, that arose from the whole genome duplication","termid":"PBO:0084453"}


id: GO:1903184
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving L-dopa.","definition_xrefs":["GOC:TermGenie","GO_REF:0000068","GOC:PARL","GOC:bf","PMID:8822146"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified amino acid metabolic process","termid":"GO:0006575"},{"relation_name":"is_a","term_name":"aromatic amino acid metabolic process","termid":"GO:0009072"},{"relation_name":"is_a","term_name":"L-amino acid metabolic process","termid":"GO:0170033"},{"relation_name":"is_a","term_name":"non-proteinogenic amino acid metabolic process","termid":"GO:0170041"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006520","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"L-dopa metabolic process","synonyms":[{"name":"L-dopa metabolism","type":"exact"}],"termid":"GO:1903184"}


id: PBO:0077917
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TPT1 pseudogene 8","termid":"PBO:0077917"}


id: MONDO:0014112
data:
  {"annotated_genes":["SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84780],"is_not":false,"summary":null,"term":"MONDO:0014112"}]},"cv_name":"mondo","definition":"Any cardiofaciocutaneous syndrome in which the cause of the disease is a mutation in the KRAS gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiofaciocutaneous syndrome","termid":"MONDO:0015280"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03453":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005267","MONDO:0005093"],"is_obsolete":false,"name":"cardiofaciocutaneous syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C3809005","DOID:0111461","GARD:15935","MEDGEN:815335","OMIM:615278"],"synonyms":[{"name":"CFC2","type":"related"},{"name":"KRAS cardiofaciocutaneous syndrome","type":"exact"},{"name":"cardiofaciocutaneous syndrome 2","type":"exact"},{"name":"cardiofaciocutaneous syndrome caused by mutation in KRAS","type":"exact"},{"name":"cardiofaciocutaneous syndrome caused by mutation in kras","type":"exact"},{"name":"cardiofaciocutaneous syndrome type 2","type":"exact"},{"name":"kras cardiofaciocutaneous syndrome","type":"exact"}],"termid":"MONDO:0014112","terms_by_termid":{"MONDO:0014112":null},"xrefs":{"Monarch":{"xref_id":"0014112"}}}


id: MONDO:0009273
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any complete hydatidiform mole in which the cause of the disease is a mutation in the NLRP7 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"complete hydatidiform mole","termid":"MONDO:0016785"},{"relation_name":"is_a","term_name":"gestational trophoblastic neoplasm","termid":"MONDO:0018944"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydatidiform mole, recurrent, 1","secondary_identifiers":["GARD:18365","UMLS:C3463897","OMIM:231090","MEDGEN:483038"],"synonyms":[{"name":"HYDM1","type":"related"},{"name":"NLRP7 complete hydatidiform mole","type":"exact"},{"name":"complete hydatidiform mole caused by mutation in NLRP7","type":"exact"},{"name":"gestational trophoblastic disease","type":"related"},{"name":"hydatidiform MOLE, recurrent, 1","type":"related"},{"name":"hydatidiform Mole, complete","type":"related"},{"name":"hydatidiform Mole, recurrent, type 1","type":"exact"},{"name":"hydatidiform mole","type":"related"},{"name":"hydatidiform mole, recurrent, 1","type":"exact"}],"termid":"MONDO:0009273","xrefs":{"Monarch":{"xref_id":"0009273"}}}


id: PBO:0005725
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 2C Ptc1","termid":"PBO:0005725"}


id: PBO:0046936
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 53 member B","termid":"PBO:0046936"}


id: PBO:0027769
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-long_mitotic_spindle_during_anaphase","termid":"PBO:0027769"}


id: FYPO:0003356
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which cells show increased sensitivity to papuamide B during mating. Cells stop growing (and may die) at a concentration of papuamide B that allows wild type cells to grow.","definition_xrefs":["PomBase:mah","PMID:24514900"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical","termid":"FYPO:0002683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000139","FYPO:0001985","FYPO:0002683","FYPO:0000003"],"is_obsolete":false,"name":"sensitive to papuamide B during mating","synonyms":[{"name":"sensitive to papuamide B during conjugation with cellular fusion","type":"exact"},{"name":"sensitivity to chemicals interfering with lipids during mating","type":"broad"}],"termid":"FYPO:0003356"}


id: PBO:0001404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent DNA helicase Hrp1","termid":"PBO:0001404"}


id: PBO:0043115
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytosolic iron-sulfur assembly component 2A","termid":"PBO:0043115"}


id: PBO:0043803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complexin 3","termid":"PBO:0043803"}


id: PBO:0111870
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"B-type cyclin","termid":"PBO:0111870"}


id: SO:0001613
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant with in the CDS that causes out of frame elongation of the resulting polypeptide sequence at the C terminus.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"elongated_polypeptide_C_terminal","termid":"SO:0001610"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongated_out_of_frame_polypeptide_C_terminal","synonyms":[{"name":"elongated polypeptide out of frame C terminal","type":"exact"}],"termid":"SO:0001613"}


id: PBO:0070548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7a pseudogene 14","termid":"PBO:0070548"}


id: PBO:0087666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and regulators of sterol biosynthesis for ubiquitin-mediated degradation; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids","termid":"PBO:0087666"}


id: PBO:0084745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial leucyl-tRNA synthetase; also has direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance; human homolog LARS2 can complement yeast null mutant, and is implicated in Perrault syndrome","termid":"PBO:0084745"}


id: PR:O94681
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03607","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC776.15c","secondary_identifiers":["UniProtKB:O94681"],"synonyms":[{"name":"2-oxoglutarate dehydrogenase complex component E2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"OGDC-E2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-sucB","type":"exact"},{"name":"dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94681"}


id: PBO:0064551
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POM121 transmembrane nucleoporin like 13, pseudogene","termid":"PBO:0064551"}


id: GO:0008386
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.","definition_xrefs":["EC:1.14.15.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid hydroxylase activity","termid":"GO:0008395"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016713"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"cholesterol monooxygenase (side-chain-cleaving) activity","secondary_identifiers":["RHEA:35739","MetaCyc:1.14.15.6-RXN","Reactome:R-HSA-193054","Reactome:R-HSA-193065","Reactome:R-HSA-193101"],"synonyms":[{"name":"C27-side chain cleavage enzyme","type":"related"},{"name":"Cyp11a1","type":"narrow"},{"name":"cholesterol 20-22-desmolase activity","type":"related"},{"name":"cholesterol C(20-22) desmolase activity","type":"related"},{"name":"cholesterol C20-22 desmolase activity","type":"related"},{"name":"cholesterol desmolase activity","type":"related"},{"name":"cholesterol side-chain cleavage enzyme activity","type":"related"},{"name":"cholesterol side-chain-cleaving enzyme activity","type":"related"},{"name":"cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)","type":"related"},{"name":"cytochrome P-450(scc) activity","type":"narrow"},{"name":"cytochrome P-450scc","type":"related"},{"name":"cytochrome p450(scc) activity","type":"narrow"},{"name":"cytochrome p450scc","type":"related"},{"name":"desmolase, steroid 20-22","type":"related"},{"name":"enzymes, cholesterol side-chain-cleaving","type":"related"},{"name":"steroid 20-22 desmolase activity","type":"broad"},{"name":"steroid 20-22-lyase activity","type":"broad"}],"termid":"GO:0008386"}


id: PBO:0065519
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pentatricopeptide repeat domain 1","termid":"PBO:0065519"}


id: PBO:0064385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PMS1 homolog 2, mismatch repair system component pseudogene 7","termid":"PBO:0064385"}


id: PBO:0090263
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 snoRNP-associated protein Nop14","termid":"PBO:0090263"}


id: PBO:0027744
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_nucleus_during_glucose_starvation","termid":"PBO:0027744"}


id: MONDO:0000261
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inflammatory disease involving a pathogenic inflammatory response in the pharyngeal tonsil.","definition_xrefs":["MONDO:patterns/inflammatory_disease_by_site"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tonsillitis","termid":"MONDO:0001039"},{"relation_name":"is_a","term_name":"nasopharyngitis","termid":"MONDO:0001040"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"adenoiditis","secondary_identifiers":["ICD9:474.01","MEDGEN:507401","SCTID:70020005","UMLS:C0001427","DOID:0050145","ICD10CM:J35.02"],"synonyms":[{"name":"chronic adenoiditis","type":"narrow"},{"name":"inflammation of pharyngeal tonsil","type":"exact"},{"name":"pharyngeal tonsil inflammation","type":"exact"},{"name":"pharyngeal tonsilitis","type":"exact"}],"termid":"MONDO:0000261","xrefs":{"Monarch":{"xref_id":"0000261"}}}


id: GO:0032460
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein-containing complex assembly","termid":"GO:0031333"},{"relation_name":"is_a","term_name":"regulation of protein oligomerization","termid":"GO:0032459"},{"relation_name":"negatively_regulates","term_name":"protein complex oligomerization","termid":"GO:0051259"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0065003"},{"rel_name":"negatively_regulates","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0065003"],"is_obsolete":false,"name":"negative regulation of protein oligomerization","synonyms":[{"name":"down regulation of protein oligomerization","type":"exact"},{"name":"down-regulation of protein oligomerization","type":"exact"},{"name":"downregulation of protein oligomerization","type":"exact"},{"name":"inhibition of protein oligomerization","type":"narrow"}],"termid":"GO:0032460"}


id: PBO:0076998
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THAP domain containing 12","termid":"PBO:0076998"}


id: PBO:0116858
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial membrane-associated ribosome receptor Mdm38","termid":"PBO:0116858"}


id: PBO:0028128
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_K-252a","termid":"PBO:0028128"}


id: GO:0003724
data:
  {"annotated_genes":["SJAG_04974","SJAG_02686","SJAG_03730","SJAG_01182","SJAG_00597","SJAG_03479","SJAG_02835","SJAG_04669","SJAG_02382","SJAG_00786","SJAG_02558","SJAG_01499","SJAG_00986","SJAG_02295","SJAG_05025","SJAG_03077","SJAG_02242","SJAG_04081","SJAG_05276","SJAG_00583","SJAG_01152","SJAG_04772","SJAG_04650","SJAG_04118","SJAG_00798","SJAG_03886","SJAG_03897","SJAG_04480","SJAG_03533","SJAG_02991","SJAG_00887","SJAG_04230","SJAG_00616","SJAG_02879","SJAG_00898","SJAG_02287","SJAG_03923","SJAG_16455","SJAG_03157","SJAG_02061","SJAG_01315","SJAG_03193","SJAG_04589"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[56834,57429,57847,58461,59808,60242,61151,62083,63241,64831,67249,68974,71442,71460,71720,73627,73696,75008,75044,75081,75318,75852,76723,78461,78795,78978,79410,80079,87526,95762,99127,100425,101199,102922,103323,105580,107080,107598,115234,116174,118483],"is_not":false,"summary":null,"term":"GO:0003724"},{"annotations":[73752],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034458"},{"annotations":[99675],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032574"}]},"cv_name":"molecular_function","definition":"Unwinding of an RNA helix, driven by ATP hydrolysis.","definition_xrefs":["GOC:jl","PMID:19158098"],"direct_ancestors":[{"relation_name":"is_a","term_name":"helicase activity","termid":"GO:0004386"},{"relation_name":"is_a","term_name":"ATP-dependent activity, acting on RNA","termid":"GO:0008186"},{"relation_name":"is_a","term_name":"catalytic activity, acting on RNA","termid":"GO:0140098"}],"gene_count":43,"genes_by_uniquename":{"SJAG_00583":null,"SJAG_00597":null,"SJAG_00616":null,"SJAG_00786":null,"SJAG_00798":null,"SJAG_00887":null,"SJAG_00898":null,"SJAG_00986":null,"SJAG_01152":null,"SJAG_01182":null,"SJAG_01315":null,"SJAG_01499":null,"SJAG_02061":null,"SJAG_02242":null,"SJAG_02287":null,"SJAG_02295":null,"SJAG_02382":null,"SJAG_02558":null,"SJAG_02686":null,"SJAG_02835":null,"SJAG_02879":null,"SJAG_02991":null,"SJAG_03077":null,"SJAG_03157":null,"SJAG_03193":null,"SJAG_03479":null,"SJAG_03533":null,"SJAG_03730":null,"SJAG_03886":null,"SJAG_03897":null,"SJAG_03923":null,"SJAG_04081":null,"SJAG_04118":null,"SJAG_04230":null,"SJAG_04480":null,"SJAG_04589":null,"SJAG_04650":null,"SJAG_04669":null,"SJAG_04772":null,"SJAG_04974":null,"SJAG_05025":null,"SJAG_05276":null,"SJAG_16455":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0140098","GO:0003824"],"is_obsolete":false,"name":"RNA helicase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000003":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-72647","Reactome:R-HSA-9770131","GO:0004004","Reactome:R-HSA-9770141","Reactome:R-HSA-9770142","Reactome:R-HSA-9770145","Reactome:R-HSA-9770129","MetaCyc:RXN-11109","EC:3.6.4.13"],"synonyms":[{"name":"ATP-dependent RNA helicase activity","type":"exact"}],"termid":"GO:0003724","terms_by_termid":{"GO:0003724":null,"GO:0032574":null,"GO:0034458":null}}


id: GO:0070896
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of transposon integration (obsolete GO:0070896)","synonyms":[{"name":"activation of transposon integration","type":"narrow"},{"name":"stimulation of transposon integration","type":"narrow"},{"name":"up regulation of transposon integration","type":"exact"},{"name":"up-regulation of transposon integration","type":"exact"},{"name":"upregulation of transposon integration","type":"exact"}],"termid":"GO:0070896"}


id: PBO:0016948
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Pos1","termid":"PBO:0016948"}


id: PBO:0080536
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WASH and IL9R antisense RNA 1","termid":"PBO:0080536"}


id: PR:Q9UUD9
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC17G9.13c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UUD9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C17G9.13c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC17G9.13c","synonyms":[{"name":"Spom972h-SPBC17G9.13c","type":"exact"}],"termid":"PR:Q9UUD9"}


id: GO:0009384
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.","definition_xrefs":["EC:2.7.1.60"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"},{"relation_name":"is_a","term_name":"carbohydrate kinase activity","termid":"GO:0019200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0016301","GO:0003674"],"is_obsolete":false,"name":"N-acylmannosamine kinase activity","secondary_identifiers":["MetaCyc:N-ACYLMANNOSAMINE-KINASE-RXN","Reactome:R-HSA-4088322","Reactome:R-HSA-4085028","RHEA:23832"],"synonyms":[{"name":"ATP:N-acetylmannosamine 6-phosphotransferase activity","type":"related"},{"name":"ATP:N-acyl-D-mannosamine 6-phosphotransferase activity","type":"related"},{"name":"N-acetylmannosamine kinase activity","type":"related"},{"name":"N-acyl-D-mannosamine kinase activity","type":"related"},{"name":"acetylamidodeoxymannokinase activity","type":"related"},{"name":"acetylmannosamine kinase activity","type":"related"},{"name":"acylaminodeoxymannokinase activity","type":"related"},{"name":"acylmannosamine kinase (phosphorylating)","type":"related"},{"name":"acylmannosamine kinase activity","type":"related"}],"termid":"GO:0009384"}


id: GO:0052118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete positive energy taxis in host environment (obsolete GO:0052118)","synonyms":[{"name":"positive energy taxis in response to host environment","type":"exact"}],"termid":"GO:0052118"}


id: GO:0016335
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"morphogenesis of an epithelium","termid":"GO:0002009"},{"relation_name":"is_a","term_name":"post-embryonic animal morphogenesis","termid":"GO:0009886"},{"relation_name":"part_of","term_name":"instar larval development","termid":"GO:0002168"},{"relation_name":"part_of","term_name":"imaginal disc morphogenesis","termid":"GO:0007560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"morphogenesis of larval imaginal disc epithelium","termid":"GO:0016335"}


id: MONDO:0007605
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibrinolytic defect","secondary_identifiers":["MESH:C565017","MEDGEN:338221","OMIM:134900","UMLS:C1851184"],"synonyms":[{"name":"fibrinolytic defect","type":"exact"}],"termid":"MONDO:0007605","xrefs":{"Monarch":{"xref_id":"0007605"}}}


id: PBO:0003518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acid phosphatase (predicted)","termid":"PBO:0003518"}


id: PBO:0048234
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G antigen 2E","termid":"PBO:0048234"}


id: GO:0048304
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of isotype switching","termid":"GO:0045830"},{"relation_name":"is_a","term_name":"regulation of isotype switching to IgG isotypes","termid":"GO:0048302"},{"relation_name":"positively_regulates","term_name":"isotype switching to IgG isotypes","termid":"GO:0048291"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006310"},{"rel_name":"positively_regulates","termid":"GO:0006310"},{"rel_name":"positively_regulates","termid":"GO:0006259"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006310","GO:0006259","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of isotype switching to IgG isotypes","synonyms":[{"name":"activation of isotype switching to IgG isotypes","type":"narrow"},{"name":"positive regulation of class switch recombination to IgG isotypes","type":"exact"},{"name":"positive regulation of class switching to IgG isotypes","type":"exact"},{"name":"positive regulation of isotype switch recombination to IgG isotypes","type":"exact"},{"name":"stimulation of isotype switching to IgG isotypes","type":"narrow"},{"name":"up regulation of isotype switching to IgG isotypes","type":"exact"},{"name":"up-regulation of isotype switching to IgG isotypes","type":"exact"},{"name":"upregulation of isotype switching to IgG isotypes","type":"exact"}],"termid":"GO:0048304"}


id: PBO:0060517
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"napsin B aspartic peptidase, pseudogene","termid":"PBO:0060517"}


id: MONDO:0005718
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Virus diseases caused by coronaviridae.","definition_xrefs":["MESH:D003333"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Nidovirales infectious disease","termid":"MONDO:0005876"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Coronaviridae infectious disease","secondary_identifiers":["EFO:0007223","MEDGEN:40491","UMLS:C0010078"],"termid":"MONDO:0005718","xrefs":{"Monarch":{"xref_id":"0005718"}}}


id: PBO:0088078
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin-specific protease that cleaves Ub-protein fusions; UBP13 has a paralog, UBP9, that arose from the whole genome duplication","termid":"PBO:0088078"}


id: PBO:0063782
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PHD finger protein 7","termid":"PBO:0063782"}


id: GO:0009012
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H+.","definition_xrefs":["EC:2.7.7.47","RHEA:20245"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoglycoside nucleotidyltransferase activity","termid":"GO:0034068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016779"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016779","GO:0003674"],"is_obsolete":false,"name":"aminoglycoside 3''-adenylyltransferase activity","secondary_identifiers":["MetaCyc:STREPTOMYCIN-3-ADENYLYLTRANSFERASE-RXN","KEGG_REACTION:R02226"],"synonyms":[{"name":"AAD (3'')","type":"related"},{"name":"ATP:streptomycin 3''-adenylyltransferase activity","type":"narrow"},{"name":"streptomycin 3''-adenylyltransferase activity","type":"narrow"}],"termid":"GO:0009012"}


id: GO:0039575
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2.","definition_xrefs":["PMID:16987978","PMID:19254804","PMID:10523853"],"gene_count":0,"genotype_count":0,"name":"obsolete suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation (obsolete GO:0039575)","synonyms":[{"name":"inhibition by virus of host TYK2 activation","type":"broad"},{"name":"inhibition by virus of host TYK2 phosphorylation","type":"exact"}],"termid":"GO:0039575"}


id: SO:0005847
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene that is a member of a gene cassette, which is a mobile genetic element.","direct_ancestors":[{"relation_name":"is_a","term_name":"gene_cassette_member","termid":"SO:0005848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cassette_array_member","synonyms":[{"name":"cassette array member","type":"exact"}],"termid":"SO:0005847"}


id: PBO:0083870
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-Box protein involved in proteasome-dependent degradation of Aah1p; involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1","termid":"PBO:0083870"}


id: GO:0170003
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of heme B from one side of a membrane to the other.","definition_xrefs":["PMID:15369674","PMID:9657107","PMID:20610401","PMID:32121449"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heme transmembrane transporter activity","termid":"GO:0015232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"heme B transmembrane transporter activity","termid":"GO:0170003"}


id: GO:0160182
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a quinol + nitrate = a quinone + H2O + nitrite.","definition_xrefs":["RHEA:56144"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nitrate reductase activity","termid":"GO:0008940"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"nitrate reductase (quinone) activity","secondary_identifiers":["EC:1.7.5.1"],"synonyms":[{"name":"dissimilatory nitrate reductase","type":"related"},{"name":"dissimilatory nitrate reductase activity","type":"related"},{"name":"nitrate reductase A activity","type":"related"},{"name":"nitrate reductase Z activity","type":"related"},{"name":"quinol-nitrate oxidoreductase activity","type":"related"}],"termid":"GO:0160182"}


id: MONDO:0000929
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare variant of melanoma with a vertical growth phase. It presents as a nodular or polypoid skin lesion. It is characterized by the presence of nodules which contain large melanoma cells with clear, foamy or finely vacuolated cytoplasm. The prognosis is similar to that of other melanomas matched for depth of invasion.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cutaneous melanoma","termid":"MONDO:0005012"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005093"],"is_obsolete":false,"name":"balloon cell malignant melanoma","secondary_identifiers":["DOID:10044","MEDGEN:90780","SCTID:403922007","ICDO:8722/3","NCIT:C4227","UMLS:C0334426"],"synonyms":[{"name":"balloon cell cutaneous (skin) melanoma","type":"exact"},{"name":"balloon cell malignant melanoma of skin","type":"exact"},{"name":"balloon cell malignant melanoma of the skin","type":"exact"},{"name":"balloon cell malignant skin melanoma","type":"exact"},{"name":"balloon cell melanoma","type":"exact"},{"name":"balloon cell skin melanoma","type":"exact"}],"termid":"MONDO:0000929","xrefs":{"Monarch":{"xref_id":"0000929"}}}


id: PBO:0055068
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2484","termid":"PBO:0055068"}


id: MONDO:0023232
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An often fatal inflammatory disorder that affects the myocardium. Morphologically, it is characterized by the presence of an inflammatory infiltrate in the myocardial tissue that includes multinucleated giant cells. It is often associated with the presence of an autoimmune disorder. Patients present with arrhythmias and/or heart failure. Heart transplantation is the only treatment option available.","definition_xrefs":["NCIT:C97055"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute myocarditis","termid":"MONDO:0002815"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"giant cell myocarditis","secondary_identifiers":["icd11.foundation:507103735","NORD:1183","GARD:6502","SCTID:60812006"],"synonyms":[{"name":"GCM","type":"related"},{"name":"giant cell myocarditis","type":"exact"},{"name":"idiopathic giant-cell myocarditis","type":"related"}],"termid":"MONDO:0023232","xrefs":{"Monarch":{"xref_id":"0023232"}}}


id: PBO:0053385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 312","termid":"PBO:0053385"}


id: GO:0102098
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+.","definition_xrefs":["EC:1.1.1.365","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"D-galacturonate reductase activity","secondary_identifiers":["MetaCyc:RXN-11151","RHEA:26345"],"termid":"GO:0102098"}


id: PBO:0058575
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6512","termid":"PBO:0058575"}


id: PBO:0074951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 113-2","termid":"PBO:0074951"}


id: MONDO:0008162
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"otitis media, susceptibility to","secondary_identifiers":["UMLS:C1833692","OMIM:166760","MEDGEN:318936"],"synonyms":[{"name":"OMS","type":"related"},{"name":"come/Rom","type":"related"},{"name":"otitis Media, chronic/recurrent","type":"related"},{"name":"otitis media, susceptibility to","type":"exact"}],"termid":"MONDO:0008162","xrefs":{"Monarch":{"xref_id":"0008162"}}}


id: GO:0052414
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete metabolism by host of symbiont glucan (obsolete GO:0052414)","termid":"GO:0052414"}


id: MONDO:0019213
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A inherited organic acidemia that involves the brain.","definition_xrefs":["MONDO:patterns/location"],"gene_count":0,"genotype_count":0,"name":"obsolete cerebral organic aciduria (obsolete MONDO:0019213)","secondary_identifiers":["icd11.foundation:1644149132","Orphanet:79158"],"synonyms":[{"name":"brain inherited organic acidemia","type":"exact"},{"name":"inherited organic acidemia of brain","type":"exact"}],"termid":"MONDO:0019213","xrefs":{"Monarch":{"xref_id":"0019213"}}}


id: PBO:0065494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome assembly chaperone 3","termid":"PBO:0065494"}


id: PBO:0091900
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wtf antidote-like meiotic drive suppressor Wtf5","termid":"PBO:0091900"}


id: PBO:0005279
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S. Pombe Centromere","termid":"PBO:0005279"}


id: GO:0008839
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.","definition_xrefs":["EC:1.17.1.8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"4-hydroxy-tetrahydrodipicolinate reductase","secondary_identifiers":["MetaCyc:RXN-14014"],"synonyms":[{"name":"2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity","type":"related"},{"name":"dihydrodipicolinate reductase activity","type":"exact"},{"name":"dihydrodipicolinic acid reductase activity","type":"related"}],"termid":"GO:0008839"}


id: PBO:0060542
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAV2 antisense RNA 2","termid":"PBO:0060542"}


id: PBO:0004762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy associated protein Atg3","termid":"PBO:0004762"}


id: MONDO:0001316
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An infectious meningitis caused by infection with Streptococcus.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial meningitis","termid":"MONDO:0006670"},{"relation_name":"is_a","term_name":"streptococcal infection","termid":"MONDO:0021680"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"streptococcal meningitis","secondary_identifiers":["SCTID:4510004","MEDGEN:509616","ICD9:320.2","DOID:11574","UMLS:C0154639","ICD10CM:G00.2"],"synonyms":[{"name":"Streptococcus caused infectious meningitis","type":"exact"},{"name":"Streptococcus infectious meningitis","type":"exact"}],"termid":"MONDO:0001316","xrefs":{"Monarch":{"xref_id":"0001316"}}}


id: FYPO:0000107
data:
  {"alleles_by_uniquename":{"SJAG_00266:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00266","name":"atf1delta","uniquename":"SJAG_00266:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[118954,118955,119172,119173],"is_not":false,"summary":null,"term":"FYPO:0000107"}]},"cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to latrunculin A. Cells stop growing (and may die) at a concentration of latrunculin A that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00266":null,"SJAG_02592":null},"genotype_count":2,"genotypes_by_uniquename":{"atf1delta":{"display_name":"atf1delta","display_uniquename":"atf1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00266:allele-1","expression":"Null"}]}]},"sty1delta":{"display_name":"sty1delta","display_uniquename":"sty1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02592:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000139","FYPO:0000003","FYPO:0002683"],"is_obsolete":false,"name":"sensitive to latrunculin A","references_by_uniquename":{"PMID:32915139":null,"PMID:33791858":null},"single_locus_annotated_genes":["SJAG_02592","SJAG_00266"],"single_locus_genotype_uniquenames":["sty1delta","atf1delta"],"synonyms":[{"name":"hypersensitive to latrunculin A","type":"exact"},{"name":"sensitive to LAT-A","type":"exact"},{"name":"sensitive to LatA","type":"exact"},{"name":"sensitive to latrunculin A during mitotic cell cycle","type":"related"},{"name":"sensitive to latrunculin A during vegetative growth","type":"exact"}],"termid":"FYPO:0000107","terms_by_termid":{"FYECO:0000137":null,"FYPO:0000107":null,"FYPO_EXT:0000001":null}}


id: GO:0140490
data:
  {"annotated_genes":["SJAG_02609","SJAG_02886","SJAG_03835","SJAG_00856","SJAG_01756","SJAG_01215"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[78702,99874,106248,109412,110382,117003],"is_not":false,"summary":null,"term":"GO:0140490"}]},"cv_name":"molecular_function","definition":"The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly.","definition_xrefs":["PMID:21993292","PMID:20631709"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molecular template activity","termid":"GO:0140489"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00856":null,"SJAG_01215":null,"SJAG_01756":null,"SJAG_02609":null,"SJAG_02886":null,"SJAG_03835":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674"],"is_obsolete":false,"name":"microtubule nucleator activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"microtubule nucleation template activity","type":"exact"}],"termid":"GO:0140490","terms_by_termid":{"GO:0140490":null}}


id: PBO:0058351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4724","termid":"PBO:0058351"}


id: PBO:0055928
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 37 member A16, pseudogene","termid":"PBO:0055928"}


id: PBO:0086141
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for N-glycan mannosylphosphorylation; non-essential gene; transcription repressed by Rm101p; MNN14 has a paralog, MNN4, that arose from the whole genome duplication","termid":"PBO:0086141"}


id: PBO:0091599
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynactin complex subunit Mug5","termid":"PBO:0091599"}


id: PBO:0040602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BAG cochaperone 6","termid":"PBO:0040602"}


id: PBO:0086492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative peroxisomal membrane protein; required for import of peroxisomal proteins; functionally complements a Pichia pastoris pex22 mutation","termid":"PBO:0086492"}


id: FYPO:0006054
data:
  {"alleles_by_uniquename":{"SJAG_02763:allele-4":{"allele_type":"amino_acid_mutation","description":"S235E; S651E","gene_uniquename":"SJAG_02763","name":"ned1S235E/S651E","synonyms":[{"name":"phosphomimetic","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-4"},"SJAG_02763:allele-5":{"allele_type":"amino_acid_mutation","description":"S499E; S538E; T620E; T638E; S651E","gene_uniquename":"SJAG_02763","name":"ned1-5E","uniquename":"SJAG_02763:allele-5"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[119303,119306],"is_not":false,"summary":null,"term":"FYPO:0006054"}]},"cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the occurrence of lipid droplet formation is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_output","term_name":"lipid droplets present in decreased numbers","termid":"FYPO:0002552"},{"relation_name":"is_a","term_name":"abnormal cellular component organization","termid":"FYPO:0000335"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02763":null},"genotype_count":2,"genotypes_by_uniquename":{"ned1-5E-S499E__S538E__T620E__T638E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"ned1-5E(S499E; S538E; T620E; T638E; S651E aa)","display_uniquename":"ned1-5E-S499E__S538E__T620E__T638E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02763:allele-5","expression":"Not assayed or wild type"}]}]},"ned1S235E_S651E-S235E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"ned1S235E/S651E(S235E; S651E aa)","display_uniquename":"ned1S235E_S651E-S235E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02763:allele-4","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased lipid droplet formation","references_by_uniquename":{"PMID:26774782":null},"single_locus_annotated_genes":["SJAG_02763"],"single_locus_genotype_uniquenames":["ned1-5E-S499E__S538E__T620E__T638E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type","ned1S235E_S651E-S235E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type"],"synonyms":[{"name":"decreased lipid droplet assembly","type":"exact"},{"name":"decreased lipid particle formation","type":"exact"},{"name":"reduced lipid droplet formation","type":"exact"}],"termid":"FYPO:0006054","terms_by_termid":{"FYPO:0006054":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null}}


id: GO:1902216
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway.","definition_xrefs":["GOC:TermGenie","PMID:17210636"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cytokine-mediated signaling pathway","termid":"GO:0001961"},{"relation_name":"is_a","term_name":"regulation of interleukin-4-mediated signaling pathway","termid":"GO:1902214"},{"relation_name":"positively_regulates","term_name":"interleukin-4-mediated signaling pathway","termid":"GO:0035771"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of interleukin-4-mediated signaling pathway","synonyms":[{"name":"activation of IL-4-mediated signaling pathway","type":"narrow"},{"name":"activation of interleukin-4-mediated signaling pathway","type":"narrow"},{"name":"activation of interleukin-4-mediated signalling pathway","type":"narrow"},{"name":"positive regulation of IL-4-mediated signaling pathway","type":"exact"},{"name":"positive regulation of interleukin-4-mediated signalling pathway","type":"exact"},{"name":"up regulation of IL-4-mediated signaling pathway","type":"exact"},{"name":"up regulation of interleukin-4-mediated signaling pathway","type":"exact"},{"name":"up regulation of interleukin-4-mediated signalling pathway","type":"exact"},{"name":"up-regulation of IL-4-mediated signaling pathway","type":"exact"},{"name":"up-regulation of interleukin-4-mediated signaling pathway","type":"exact"},{"name":"up-regulation of interleukin-4-mediated signalling pathway","type":"exact"},{"name":"upregulation of IL-4-mediated signaling pathway","type":"exact"},{"name":"upregulation of interleukin-4-mediated signaling pathway","type":"exact"},{"name":"upregulation of interleukin-4-mediated signalling pathway","type":"exact"}],"termid":"GO:1902216"}


id: GO:0018043
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.","definition_xrefs":["RESID:AA0090"],"gene_count":0,"genotype_count":0,"name":"obsolete C-terminal peptidyl-isoleucine amidation (obsolete GO:0018043)","termid":"GO:0018043"}


id: MONDO:0011793
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"celiac disease","termid":"MONDO:0005130"},{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"celiac disease, susceptibility to, 5","secondary_identifiers":["MEDGEN:337622","OMIM:607202","UMLS:C1846631"],"synonyms":[{"name":"CELIAC5","type":"exact"},{"name":"GSES","type":"related"},{"name":"celiac disease, susceptibility to, 5","type":"exact"},{"name":"gluten-sensitive enteropathy, susceptibility to, 5","type":"related"}],"termid":"MONDO:0011793","xrefs":{"Monarch":{"xref_id":"0011793"}}}


id: PBO:0000110
data:
  {"annotation_feature_type":"gene","cv_name":"species_dist","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"orthologs cannot be distinguished","termid":"PBO:0000110"}


id: MONDO:0019253
data:
  {"annotated_genes":["SJAG_04203"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86292],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044330"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of biogenic amine metabolism and transport","termid":"MONDO:0019250"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04203":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"metabolic disease involving other neurotransmitter deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1843271","GARD:18979","Orphanet:79219","icd11.foundation:946446904","UMLS:C5681275"],"termid":"MONDO:0019253","terms_by_termid":{"MONDO:0044330":null},"xrefs":{"Monarch":{"xref_id":"0019253"}}}


id: GO:1904781
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:17115027"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein localization","termid":"GO:1903829"},{"relation_name":"is_a","term_name":"regulation of protein localization to centrosome","termid":"GO:1904779"},{"relation_name":"positively_regulates","term_name":"protein localization to centrosome","termid":"GO:0071539"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein localization to centrosome","synonyms":[{"name":"activation of protein localisation to centrosome","type":"narrow"},{"name":"activation of protein localization to centrosome","type":"narrow"},{"name":"positive regulation of protein localisation to centrosome","type":"exact"},{"name":"up regulation of protein localisation to centrosome","type":"exact"},{"name":"up regulation of protein localization to centrosome","type":"exact"},{"name":"up-regulation of protein localisation to centrosome","type":"exact"},{"name":"up-regulation of protein localization to centrosome","type":"exact"},{"name":"upregulation of protein localisation to centrosome","type":"exact"},{"name":"upregulation of protein localization to centrosome","type":"exact"}],"termid":"GO:1904781"}


id: PBO:0087439
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit F of the V1 peripheral membrane domain of V-ATPase; part of the electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane; the V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase) has eight subunits","termid":"PBO:0087439"}


id: PBO:0012244
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Continues to Grow in Stationary","termid":"PBO:0012244"}


id: GO:0010034
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.","definition_xrefs":["GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to acetate","termid":"GO:0010034"}


id: MONDO:0018199
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"New-onset refractory status epilepticus is an acute encephalopathy with inflammation-mediated status epilepticus characterized by an acute refractory status epilepticus, typically of the tonic-clonic type, following prodromal symptoms of confusion, fever, fatigue, headache, symptoms of gastrointestinal or upper respiratory tract infection, behavioral changes or hallucinations. Brain MRI abnormalities and abnormal findings in CSF, including pleocytosis and/or elevated protein levels, are frequently found during acute episode. Treatment-resistant epilepsy, cognitive and psychiatric impairments are usual consequences.","definition_xrefs":["Orphanet:363558"],"direct_ancestors":[{"relation_name":"is_a","term_name":"childhood-onset epilepsy syndrome","termid":"MONDO:0020072"},{"relation_name":"is_a","term_name":"adolescent-onset epilepsy syndrome","termid":"MONDO:0020073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"new-onset refractory status epilepticus","secondary_identifiers":["GARD:12244","MEDGEN:1657271","UMLS:C4749462"],"synonyms":[{"name":"De novo cryptogenic refractory multifocal febrile status epilepticus","type":"related"},{"name":"NORSE","type":"exact"},{"name":"New onset refractory status epilepticus","type":"related"},{"name":"Norse","type":"exact"}],"termid":"MONDO:0018199","xrefs":{"Monarch":{"xref_id":"0018199"}}}


id: GO:0009815
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + dehydroascorbate + ethylene + 2 H2O + hydrogen cyanide. Ethene is also known as ethylene.","definition_xrefs":["RHEA:23640"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen","termid":"GO:0016715"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"1-aminocyclopropane-1-carboxylate oxidase activity","secondary_identifiers":["KEGG_REACTION:R07214","MetaCyc:ETHYL-RXN","EC:1.14.17.4"],"synonyms":[{"name":"1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming)","type":"related"},{"name":"ACC oxidase activity","type":"exact"},{"name":"aminocyclopropanecarboxylate oxidase activity","type":"related"},{"name":"ethene-forming enzyme","type":"broad"},{"name":"ethylene-forming enzyme","type":"broad"}],"termid":"GO:0009815"}


id: PBO:0048099
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ferritin mitochondrial","termid":"PBO:0048099"}


id: PBO:0067383
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 487, pseudogene","termid":"PBO:0067383"}


id: PBO:0074627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 23","termid":"PBO:0074627"}


id: MONDO:0031068
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease","termid":"MONDO:0015626"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease, axonal, IIa 2II","secondary_identifiers":["MEDGEN:1824000","OMIM:620068","UMLS:C5774227"],"synonyms":[{"name":"CMT2II","type":"exact"},{"name":"charcot-marie-tooth disease, axonal, IIa 2II","type":"exact"},{"name":"charcot-marie-tooth neuropathy, IIa 2II","type":"exact"}],"termid":"MONDO:0031068","xrefs":{"Monarch":{"xref_id":"0031068"}}}


id: PBO:0052113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium voltage-gated channel subfamily C member 1","termid":"PBO:0052113"}


id: PBO:0077993
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TraB domain containing 2A","termid":"PBO:0077993"}


id: MONDO:0000269
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete inhalation anthrax (obsolete MONDO:0000269)","termid":"MONDO:0000269","xrefs":{"Monarch":{"xref_id":"0000269"}}}


id: PBO:0116613
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 3139","termid":"PBO:0116613"}


id: FYPO:0002449
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer signal recognition particles (SRPs) than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal subcellular component during vegetative growth","termid":"FYPO:0001322"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"signal recognition particles present in decreased numbers","synonyms":[{"name":"SRPs present in decreased numbers","type":"exact"},{"name":"decreased level of SRPs","type":"related"},{"name":"decreased signal recognition particle formation during vegetative growth","type":"related"},{"name":"fewer signal recognition particles present during vegetative growth","type":"exact"},{"name":"signal recognition particles present in decreased numbers during mitotic cell cycle","type":"related"},{"name":"signal recognition particles present in decreased numbers during vegetative growth","type":"exact"},{"name":"signal recognition particles present in reduced numbers","type":"exact"}],"termid":"FYPO:0002449"}


id: GO:1900863
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of small molecule metabolic process","termid":"GO:0062013"},{"relation_name":"is_a","term_name":"positive regulation of secondary metabolite biosynthetic process","termid":"GO:1900378"},{"relation_name":"is_a","term_name":"regulation of cordyol C biosynthetic process","termid":"GO:1900861"},{"relation_name":"positively_regulates","term_name":"cordyol C biosynthetic process","termid":"GO:1900799"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"positively_regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"positively_regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0044281","GO:0019748","GO:0008150"],"is_obsolete":false,"name":"positive regulation of cordyol C biosynthetic process","synonyms":[{"name":"activation of cordyol C biosynthetic process","type":"narrow"},{"name":"up regulation of cordyol C biosynthetic process","type":"exact"},{"name":"up-regulation of cordyol C biosynthetic process","type":"exact"},{"name":"upregulation of cordyol C biosynthetic process","type":"exact"}],"termid":"GO:1900863"}


id: PBO:0055685
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipoyltransferase 1","termid":"PBO:0055685"}


id: MONDO:0005065
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.","definition_xrefs":["NCIT:C3234"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesothelial neoplasm","termid":"MONDO:0006856"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mesothelioma","secondary_identifiers":["ICD10CM:C45","MESH:D008654","UMLS:C0025500","EFO:0000588","MEDGEN:9975"],"synonyms":[{"name":"mesothelioma","type":"exact"}],"termid":"MONDO:0005065","xrefs":{"Monarch":{"xref_id":"0005065"}}}


id: PBO:0046217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin C pseudogene 10","termid":"PBO:0046217"}


id: FYPO:0000626
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the initiation of premeiotic DNA replication is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA replication initiation","termid":"FYPO:0000176"},{"relation_name":"is_a","term_name":"abnormal premeiotic DNA replication","termid":"FYPO:0000625"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000293"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000631","FYPO:0000002","FYPO:0000293"],"is_obsolete":false,"name":"abnormal initiation of premeiotic DNA replication","synonyms":[{"name":"abnormal initiation of meiotic DNA synthesis","type":"related"},{"name":"abnormal initiation of premeiotic DNA synthesis","type":"related"},{"name":"abnormal meiotic DNA replication initiation","type":"related"},{"name":"abnormal premeiotic DNA replication initiation","type":"exact"}],"termid":"FYPO:0000626"}


id: MONDO:0017653
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete epilepsy and/or ataxia with myoclonus as major feature (obsolete MONDO:0017653)","secondary_identifiers":["Orphanet:306756"],"termid":"MONDO:0017653","xrefs":{"Monarch":{"xref_id":"0017653"}}}


id: PBO:0113267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Phospholipase B; hydrolyses phosphatidylserine; minor activity against cardiolipin and PtdEtn; required for lysis of autophagic and CVT bodies; targeted to the vacuole via the Pep1p-dependent endosomal VPS pathway; targeted to intravacuolar vesicles during autophagy by the MVB pathway; maintains lipid droplet quantity after the diauxic shift; regulates lipolysis; single membrane spanning protein with cytosolic N-term and the rest in the ER lumen; expression regulated by Yap1p during autophagy","termid":"PBO:0113267"}


id: GO:0031948
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of glucocorticoid metabolic process","termid":"GO:0031945"},{"relation_name":"is_a","term_name":"regulation of glucocorticoid biosynthetic process","termid":"GO:0031946"},{"relation_name":"is_a","term_name":"positive regulation of steroid hormone biosynthetic process","termid":"GO:0090031"},{"relation_name":"positively_regulates","term_name":"glucocorticoid biosynthetic process","termid":"GO:0006704"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"positively_regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"positive regulation of glucocorticoid biosynthetic process","synonyms":[{"name":"activation of glucocorticoid biosynthetic process","type":"narrow"},{"name":"stimulation of glucocorticoid biosynthetic process","type":"narrow"},{"name":"up regulation of glucocorticoid biosynthetic process","type":"exact"},{"name":"up-regulation of glucocorticoid biosynthetic process","type":"exact"},{"name":"upregulation of glucocorticoid biosynthetic process","type":"exact"}],"termid":"GO:0031948"}


id: GO:0048319
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the axial mesoderm are generated and organized.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesoderm morphogenesis","termid":"GO:0048332"},{"relation_name":"part_of","term_name":"axial mesoderm development","termid":"GO:0048318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"axial mesoderm morphogenesis","termid":"GO:0048319"}


id: GO:0006909
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endocytosis","termid":"GO:0006897"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0016192","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"phagocytosis","secondary_identifiers":["Reactome:R-HSA-9664417","Wikipedia:Phagocytosis"],"termid":"GO:0006909"}


id: PR:O14107
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dni1 gene.","definition_xrefs":["UniProtKB:O14107","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell fusion protein dni1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC31G5.07","synonyms":[{"name":"Spom972h-dni1","type":"exact"},{"name":"delayed minus-nitrogen induction protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14107"}


id: GO:0097492
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.","definition_xrefs":["GOC:BHF","GOC:rl","PMID:22790009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"axon guidance","termid":"GO:0007411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sympathetic neuron axon guidance","synonyms":[{"name":"sympathetic neuron axon chemotaxis","type":"related"},{"name":"sympathetic neuron axon growth cone guidance","type":"narrow"},{"name":"sympathetic neuron axon pathfinding","type":"exact"}],"termid":"GO:0097492"}


id: PBO:0003755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding protein Mlo3","termid":"PBO:0003755"}


id: MONDO:0007344
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of cluster headache syndrome that is caused by an inherited modification of the individual's genome.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cluster headache syndrome","termid":"MONDO:0043537"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cluster headache, familial","secondary_identifiers":["OMIM:119915","UMLS:C1861513","MEDGEN:350040","MESH:C566117"],"synonyms":[{"name":"cluster headache, familial","type":"exact"},{"name":"hereditary cluster headache syndrome","type":"exact"}],"termid":"MONDO:0007344","xrefs":{"Monarch":{"xref_id":"0007344"}}}


id: MONDO:0006316
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of nervous system tumors which display neuronal differentiation. It includes tumors that are composed of immature round cells and tumors that display advanced differentiation and the formation of ganglion cells.","definition_xrefs":["NCIT:C6963"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primitive neuroectodermal tumor","termid":"MONDO:0005462"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neuroblastic tumor","secondary_identifiers":["UMLS:C1334953","MEDGEN:233228","EFO:1000393"],"synonyms":[{"name":"neuroblastic tumor","type":"exact"}],"termid":"MONDO:0006316","xrefs":{"Monarch":{"xref_id":"0006316"}}}


id: PBO:0085820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; expressed during diauxic shift and stationary phase, and negatively regulated by glucose; expression is regulated by Msn2p/Msn4p; overexpression slows down progression through meiosis and improves fermentative efficiency; YNR034W-A has a paralog, YCR075W-A, that arose from the whole genome duplication","termid":"PBO:0085820"}


id: RO:0002372
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.","direct_ancestors":[{"relation_name":"is_a","term_name":"attached_to","termid":"RO:0002371"},{"relation_name":"is_a","term_name":"biomechanically_related_to","termid":"RO:0002567"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_muscle_origin","termid":"RO:0002372"}


id: MONDO:0003025
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An angiosarcoma characterized by the presence of malignant spindle endothelial cells.","definition_xrefs":["NCIT:C9426"],"direct_ancestors":[{"relation_name":"is_a","term_name":"angiosarcoma","termid":"MONDO:0016982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"conventional angiosarcoma","secondary_identifiers":["UMLS:C1333155","MEDGEN:234174","DOID:4512"],"synonyms":[{"name":"conventional angiosarcoma","type":"exact"}],"termid":"MONDO:0003025","xrefs":{"Monarch":{"xref_id":"0003025"}}}


id: GO:1903545
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.","definition_xrefs":["GOC:mr","GO_REF:0000071","GOC:TermGenie","PMID:9734870"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to fatty acid","termid":"GO:0071398"},{"relation_name":"is_a","term_name":"response to butyrate","termid":"GO:1903544"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to butyrate","termid":"GO:1903545"}


id: MONDO:1011774
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"digital dermatitis, non-human animal","secondary_identifiers":["OMIA:002224"],"termid":"MONDO:1011774","xrefs":{"Monarch":{"xref_id":"1011774"}}}


id: PBO:0069215
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 470, pseudogene","termid":"PBO:0069215"}


id: PBO:0088808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongator complex associated protein Kti12","termid":"PBO:0088808"}


id: MONDO:0007797
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The HDR syndrome is an inherited condition consisting of hypoparathyroidism, sensorineural deafness and renal disease.","definition_xrefs":["Orphanet:2237"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"partial deletion of the short arm of chromosome 10","termid":"MONDO:0016892"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypoparathyroidism-deafness-renal disease syndrome","secondary_identifiers":["NORD:837","GARD:2911","MESH:C537907","DOID:0060878","NCIT:C130983","SCTID:724282009","MEDGEN:374443","UMLS:C1840333","OMIM:146255"],"synonyms":[{"name":"Barakat Syndrome","type":"exact"},{"name":"Barakat syndrome","type":"exact"},{"name":"HDR","type":"related"},{"name":"HDR syndrome","type":"exact"},{"name":"hypoparathyroidism, deafness, and renal anomalies syndrome","type":"exact"},{"name":"hypoparathyroidism, sensorineural deafness, and renal disease","type":"exact"},{"name":"hypoparathyroidism, sensorineural deafness, and renal dysplasia","type":"related"},{"name":"hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome","type":"related"},{"name":"hypoparathyroidism-deafness-renal disease syndrome","type":"exact"},{"name":"nephrosis, nerve deafness, and hypoparathyroidism","type":"related"}],"termid":"MONDO:0007797","xrefs":{"Monarch":{"xref_id":"0007797"}}}


id: GO:0005360
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.","definition_xrefs":["GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"D-glucose:proton symporter activity","termid":"GO:0005356"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"insulin-responsive D-glucose:proton symporter activity","synonyms":[{"name":"insulin-responsive glucose:proton symporter activity","type":"exact"},{"name":"insulin-responsive hydrogen:glucose symporter activity","type":"exact"},{"name":"insulin-responsive hydrogen:glucose transporter activity","type":"related"},{"name":"transepithelial hydrogen/glucose transporter activity","type":"related"}],"termid":"GO:0005360"}


id: MONDO:0015688
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"myeloid neoplasm","termid":"MONDO:0005170"},{"relation_name":"is_a","term_name":"myeloid hemopathy","termid":"MONDO:0015756"},{"relation_name":"is_a","term_name":"hematopoietic and lymphoid cell neoplasm","termid":"MONDO:0044881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2","secondary_identifiers":["Orphanet:168943","UMLS:C2827356","MEDGEN:417664","DOID:0080164","GARD:20105","NCIT:C84270"],"synonyms":[{"name":"myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1","type":"exact"},{"name":"myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1","type":"exact"},{"name":"myeloid and lymphoid neoplasms with eosinophilia and abnormalities of platelet-derived growth factor receptor alpha (PDGFRA), platelet-derived growth factor receptor beta (PDGFRB), and fibroblast growth factor receptor-1 (FGFR1) are a group of hematologic neoplasms","type":"exact"},{"name":"myeloid and lymphoid neoplasms with eosinophilia and rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2","type":"exact"},{"name":"myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2","type":"exact"},{"name":"myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement","type":"exact"},{"name":"myeloid/lymphoid neoplasms with eosinophilia and rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2","type":"exact"}],"termid":"MONDO:0015688","xrefs":{"Monarch":{"xref_id":"0015688"}}}


id: PBO:0041496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 12 open reading frame 56","termid":"PBO:0041496"}


id: PBO:0080115
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UVRAG divergent transcript","termid":"PBO:0080115"}


id: GO:0021726
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.","definition_xrefs":["GOC:dgh","GOC:cls","GO_REF:0000021","GOC:curators","GOC:jid","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neural nucleus development","termid":"GO:0048857"},{"relation_name":"part_of","term_name":"medullary reticular formation development","termid":"GO:0021723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lateral reticular nucleus development","termid":"GO:0021726"}


id: MONDO:0030538
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited dystonia","termid":"MONDO:0044807"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"dystonia 34, myoclonic","secondary_identifiers":["OMIM:619724","UMLS:C5676907","MEDGEN:1805016","DOID:0060957"],"synonyms":[{"name":"DYT34","type":"exact"}],"termid":"MONDO:0030538","xrefs":{"Monarch":{"xref_id":"0030538"}}}


id: MONDO:0010869
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary motor neuron disease","termid":"MONDO:0024257"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"motor neuron disease with dementia and ophthalmoplegia","secondary_identifiers":["MESH:C563954","MEDGEN:324986","OMIM:600333","UMLS:C1838253"],"synonyms":[{"name":"motor neuron disease with dementia and ophthalmoplegia","type":"exact"}],"termid":"MONDO:0010869","xrefs":{"Monarch":{"xref_id":"0010869"}}}


id: PBO:0058390
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4762","termid":"PBO:0058390"}


id: PomGeneEx:0000014
data:
  {"annotation_feature_type":"gene","cv_name":"PomGeneExRNA","definition":"A gene expression qualifier that indicates that an RNA is present under a given set of conditions or at an indicated time.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"present","termid":"PomGeneEx:0000005"},{"relation_name":"is_a","term_name":"RNA expression level","termid":"PomGeneEx:0000009"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA present","synonyms":[{"name":"RNA expression present","type":"exact"}],"termid":"PomGeneEx:0000014"}


id: GO:0030627
data:
  {"annotated_genes":["SJAG_03983","SJAG_00058"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[79295,113085],"is_not":false,"summary":null,"term":"GO:0030627"}]},"cv_name":"molecular_function","definition":"Binding to a pre-mRNA 5' splice site sequence.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pre-mRNA binding","termid":"GO:0036002"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00058":null,"SJAG_03983":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003723","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"pre-mRNA 5'-splice site binding","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"pre-mRNA 5' splice site binding","type":"exact"}],"termid":"GO:0030627","terms_by_termid":{"GO:0030627":null}}


id: MONDO:0019313
data:
  {"annotated_genes":["SJAG_04745","SJAG_00993","SJAG_02342","SJAG_02923","SJAG_02648","SJAG_01181","SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86231],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007918"},{"annotations":[86083],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011257"},{"annotations":[87014,87013,87012],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008104"},{"annotations":[85531],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033669"},{"annotations":[86402],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012371"},{"annotations":[86199],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013186"}]},"cv_name":"mondo","definition":"Primary lymphedema is caused by anatomic or functional defects in the lymphatic system, resulting in chronic swelling of body parts and lymphatic-system malformation.","definition_xrefs":["PMID:22831870"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"vascular disorder","termid":"MONDO:0005385"},{"relation_name":"is_a","term_name":"primary lymphedema","termid":"MONDO:0019175"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00993":null,"SJAG_01181":null,"SJAG_02342":null,"SJAG_02648":null,"SJAG_02923":null,"SJAG_03453":null,"SJAG_04745":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"lymphatic malformation","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0050580","ICD10CM:Q82.0","GARD:13057","ICD9:757.0","SCTID:254199006","UMLS:C0398368","MEDGEN:140763","OMIMPS:153100"],"synonyms":[{"name":"hereditary lymphedema","type":"exact"},{"name":"lymphedema, hereditary","type":"exact"}],"termid":"MONDO:0019313","terms_by_termid":{"MONDO:0007918":null,"MONDO:0008104":null,"MONDO:0011257":null,"MONDO:0012371":null,"MONDO:0013186":null,"MONDO:0033669":null},"xrefs":{"Monarch":{"xref_id":"0019313"}}}


id: PBO:0017683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"copper transmembrane transporter, meiotic Mfc1","termid":"PBO:0017683"}


id: GO:0015770
data:
  {"annotated_genes":["SJAG_03960"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[95530],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106082"}]},"cv_name":"biological_process","definition":"The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disaccharide transport","termid":"GO:0015766"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"sucrose transport","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0015770","terms_by_termid":{"GO:0106082":null}}


id: GO:0003177
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the pulmonary valve over time, from its formation to the mature structure.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"semi-lunar valve development","termid":"GO:1905314"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pulmonary valve development","termid":"GO:0003177"}


id: MONDO:0010928
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dwarfism, familial, with muscle spasms","secondary_identifiers":["OMIM:600771","UMLS:C1833341","MEDGEN:322168","MESH:C563447"],"synonyms":[{"name":"dwarfism familial with muscle spasms","type":"related"},{"name":"dwarfism, familial, with muscle spasms","type":"exact"},{"name":"familial dwarfism and painful muscle spasms","type":"related"}],"termid":"MONDO:0010928","xrefs":{"Monarch":{"xref_id":"0010928"}}}


id: GO:0008230
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.","definition_xrefs":["PMID:14592980","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA polymerase II transcription regulator complex","termid":"GO:0090575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"ecdysone receptor holocomplex","termid":"GO:0008230"}


id: PBO:0051257
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable (III)-38-1 (pseudogene)","termid":"PBO:0051257"}


id: PBO:0041464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 10 open reading frame 105","termid":"PBO:0041464"}


id: PBO:0060923
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurofibromin 1 pseudogene 10","termid":"PBO:0060923"}


id: FYPO:0004960
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in the mitochondria is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be measured.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA level during vegetative growth","termid":"FYPO:0001317"},{"relation_name":"is_a","term_name":"normal level of substance in mitochondrion","termid":"FYPO:0004959"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal mitochondrial RNA level","synonyms":[{"name":"normal mitochondrial RNA accumulation","type":"related"},{"name":"normal mitochondrial RNA level during mitotic cell cycle","type":"related"},{"name":"normal mitochondrial RNA level during vegetative growth","type":"exact"},{"name":"normal mitochondrial transcript level","type":"exact"}],"termid":"FYPO:0004960"}


id: GO:0060593
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.","definition_xrefs":["GOC:dph","PMID:16168142"],"gene_count":0,"genotype_count":0,"name":"obsolete Wnt signaling pathway involved in mammary gland specification (obsolete GO:0060593)","synonyms":[{"name":"Wnt receptor signaling pathway involved in mammary gland specification","type":"exact"},{"name":"Wnt receptor signalling pathway involved in mammary gland specification","type":"exact"},{"name":"Wnt-activated signaling pathway involved in mammary gland specification","type":"exact"}],"termid":"GO:0060593"}


id: PBO:0039293
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ALG9 alpha-1,2-mannosyltransferase","termid":"PBO:0039293"}


id: PBO:0058119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4422","termid":"PBO:0058119"}


id: PBO:0074234
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 47 member 2","termid":"PBO:0074234"}


id: PBO:0005278
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinetochore protein Spc7","termid":"PBO:0005278"}


id: PBO:0050530
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hippocalcin like 4","termid":"PBO:0050530"}


id: MONDO:0100173
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing leukemia, acute myeloid.","definition_xrefs":["MONDO:patterns/inherited_susceptibility"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukemia, acute myeloid, susceptibility to","secondary_identifiers":["UMLS:C3275959","MEDGEN:477590"],"termid":"MONDO:0100173","xrefs":{"Monarch":{"xref_id":"0100173"}}}


id: MOD:00114
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-cysteine residue to L-cysteine methyl ester.","definition_xrefs":["PubMed:11875433","RESID:AA0105","PubMed:1872463","Unimod:34#C-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monomethylated L-cysteine","termid":"MOD:01682"},{"relation_name":"is_a","term_name":"alpha-carboxyl methylated residue","termid":"MOD:01689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"},{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00905","MOD:00427"],"is_obsolete":false,"name":"L-cysteine methyl ester","synonyms":[{"name":"2-amino-3-mercaptopropanoic methyl ester","type":"exact"},{"name":"2-amino-3-sulfanylpropanoic methyl ester","type":"exact"},{"name":"L-cysteine methyl ester","type":"exact"},{"name":"MOD_RES Cysteine methyl ester","type":"exact"},{"name":"Methyl","type":"related"},{"name":"Methylation","type":"related"},{"name":"OMeCys","type":"exact"},{"name":"mecysteine","type":"exact"},{"name":"methyl (2R)-2-amino-3-sulfanylpropanoate","type":"exact"},{"name":"methyl L-cysteinate","type":"exact"},{"name":"methyl esterified L-cysteine","type":"exact"}],"termid":"MOD:00114"}


id: GO:0003851
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H+ + UDP.","definition_xrefs":["EC:2.4.1.47"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-galactosyltransferase activity","termid":"GO:0035250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016757","GO:0003824","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"N-acylsphingosine galactosyltransferase activity","secondary_identifiers":["Reactome:R-HSA-6785933","RHEA:13093","MetaCyc:2.4.1.47-RXN"],"synonyms":[{"name":"2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity","type":"exact"}],"termid":"GO:0003851"}


id: PBO:0027293
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-tetranucleate_vegetative_cell_with_fragmented_septum","termid":"PBO:0027293"}


id: MONDO:0019024
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare entity characterized by localized but destructive growth of a tumor consisting of highly atypical, immature mast cells.(WHO, 2001)","definition_xrefs":["NCIT:C9348"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune system cancer","termid":"MONDO:0000621"},{"relation_name":"is_a","term_name":"sarcoma","termid":"MONDO:0005089"},{"relation_name":"is_a","term_name":"mastocytosis","termid":"MONDO:0007950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570","MONDO:0004992"],"is_obsolete":false,"name":"mast cell sarcoma","secondary_identifiers":["EFO:1000364","MESH:D012515","ONCOTREE:MCSL","ICDO:9740/3","UMLS:C0036221","icd11.foundation:1993363632","SCTID:118615008","ICD9:202.6","MEDGEN:11322","Orphanet:66661","DOID:355","GARD:18870","icd11.foundation:233404891"],"synonyms":[{"name":"MCS","type":"exact"},{"name":"MCSL","type":"related"},{"name":"mast cell sarcoma","type":"exact"},{"name":"mast-cell sarcoma","type":"exact"},{"name":"sarcoma of mast cell","type":"exact"}],"termid":"MONDO:0019024","xrefs":{"Monarch":{"xref_id":"0019024"}}}


id: MONDO:0013307
data:
  {"annotated_genes":["SJAG_04473"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86997],"is_not":false,"summary":null,"term":"MONDO:0013307"}]},"cv_name":"mondo","definition":"Any mitochondrial myopathy and sideroblastic anemia in which the cause of the disease is a mutation in the YARS2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myopathy, lactic acidosis, and sideroblastic anemia","termid":"MONDO:0000863"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04473":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005066","MONDO:0004069","MONDO:0005336","MONDO:0002280"],"is_obsolete":false,"name":"myopathy, lactic acidosis, and sideroblastic anemia 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C3150802","OMIM:613561","GARD:15676","MEDGEN:462152","DOID:0111186"],"synonyms":[{"name":"MLASA2","type":"related"},{"name":"YARS2 mitochondrial myopathy and sideroblastic anaemia","type":"exact"},{"name":"YARS2 mitochondrial myopathy and sideroblastic anemia","type":"exact"},{"name":"mitochondrial myopathy and sideroblastic anaemia caused by mutation in YARS2","type":"exact"},{"name":"mitochondrial myopathy and sideroblastic anemia caused by mutation in YARS2","type":"exact"},{"name":"myopathy, lactic acidosis, and sideroblastic Anaemia type 2","type":"exact"},{"name":"myopathy, lactic acidosis, and sideroblastic Anemia type 2","type":"exact"},{"name":"myopathy, lactic acidosis, and sideroblastic anemia 2","type":"exact"}],"termid":"MONDO:0013307","terms_by_termid":{"MONDO:0013307":null},"xrefs":{"Monarch":{"xref_id":"0013307"}}}


id: FYPO:0001577
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing a tetrapeptide such as Leu-Ser-Lys-Leu as the nitrogen source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished vegetative cell population growth","termid":"FYPO:0001575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0001985","FYPO:0000139","FYPO:0002058","FYPO:0002060","FYPO:0005447","FYPO:0002057"],"is_obsolete":false,"name":"abolished cell population growth on tetrapeptide nitrogen source","synonyms":[{"name":"abolished growth on tetrapeptide nitrogen source","type":"broad"},{"name":"abolished tetrapeptide utilization","type":"related"},{"name":"abolished vegetative cell population growth on tetrapeptide nitrogen source","type":"exact"},{"name":"cell population growth on tetrapeptide nitrogen source abolished","type":"exact"}],"termid":"FYPO:0001577"}


id: MONDO:0012932
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"myopia","termid":"MONDO:0001384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"myopia 16, autosomal dominant","secondary_identifiers":["MEDGEN:390819","MESH:C567259","OMIM:612554","UMLS:C2675523"],"synonyms":[{"name":"MYP16","type":"exact"},{"name":"myopia 16","type":"exact"},{"name":"myopia 16, autosomal dominant","type":"exact"}],"termid":"MONDO:0012932","xrefs":{"Monarch":{"xref_id":"0012932"}}}


id: GO:0046923
data:
  {"annotated_genes":["SJAG_02418"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[113435],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045015"}]},"cv_name":"molecular_function","definition":"Binding to an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signal sequence binding","termid":"GO:0005048"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02418":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005048"}],"interesting_parent_ids":["GO:0005048","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"ER retention sequence binding","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"endoplasmic reticulum retention sequence binding","type":"exact"}],"termid":"GO:0046923","terms_by_termid":{"GO:0045015":null}}


id: GO:1900694
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of secondary metabolite biosynthetic process","termid":"GO:1900378"},{"relation_name":"is_a","term_name":"regulation of (+)-kotanin biosynthetic process","termid":"GO:1900692"},{"relation_name":"positively_regulates","term_name":"(+)-kotanin biosynthetic process","termid":"GO:1900596"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"positively_regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"positive regulation of (+)-kotanin biosynthetic process","synonyms":[{"name":"activation of (+)-kotanin anabolism","type":"exact"},{"name":"activation of (+)-kotanin biosynthesis","type":"exact"},{"name":"activation of (+)-kotanin biosynthetic process","type":"narrow"},{"name":"activation of (+)-kotanin formation","type":"exact"},{"name":"activation of (+)-kotanin synthesis","type":"exact"},{"name":"positive regulation of (+)-kotanin anabolism","type":"exact"},{"name":"positive regulation of (+)-kotanin biosynthesis","type":"exact"},{"name":"positive regulation of (+)-kotanin formation","type":"exact"},{"name":"positive regulation of (+)-kotanin synthesis","type":"exact"},{"name":"up regulation of (+)-kotanin anabolism","type":"exact"},{"name":"up regulation of (+)-kotanin biosynthesis","type":"exact"},{"name":"up regulation of (+)-kotanin biosynthetic process","type":"exact"},{"name":"up regulation of (+)-kotanin formation","type":"exact"},{"name":"up regulation of (+)-kotanin synthesis","type":"exact"},{"name":"up-regulation of (+)-kotanin anabolism","type":"exact"},{"name":"up-regulation of (+)-kotanin biosynthesis","type":"exact"},{"name":"up-regulation of (+)-kotanin biosynthetic process","type":"exact"},{"name":"up-regulation of (+)-kotanin formation","type":"exact"},{"name":"up-regulation of (+)-kotanin synthesis","type":"exact"},{"name":"upregulation of (+)-kotanin anabolism","type":"exact"},{"name":"upregulation of (+)-kotanin biosynthesis","type":"exact"},{"name":"upregulation of (+)-kotanin biosynthetic process","type":"exact"},{"name":"upregulation of (+)-kotanin formation","type":"exact"},{"name":"upregulation of (+)-kotanin synthesis","type":"exact"}],"termid":"GO:1900694"}


id: MONDO:0001699
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A dermatophytosis that involves the hands.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dermatophytosis","termid":"MONDO:0004678"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"tinea manuum","secondary_identifiers":["SCTID:48971001","ICD10CM:B35.2","MEDGEN:509222","DOID:13369","UMLS:C0153246","ICD9:110.2"],"synonyms":[{"name":"Tinea manus","type":"exact"},{"name":"dermatophytosis of hand","type":"exact"},{"name":"dermatophytosis of manus","type":"exact"},{"name":"manus dermatophytosis","type":"exact"}],"termid":"MONDO:0001699","xrefs":{"Monarch":{"xref_id":"0001699"}}}


id: PBO:0011512
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"merged with ncRNA SPNCRNA.64","termid":"PBO:0011512"}


id: GO:0140767
data:
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id: PBO:0110315
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id: MONDO:0020105
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id: GO:0004790
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id: PBO:0091283
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id: GO:0047644
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id: PBO:0029960
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id: PATO:0000967
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id: MONDO:0000567
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id: PBO:0059743
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id: FYPO:0002755
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id: GO:1901293
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id: GO:0010445
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id: PBO:0012301
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id: MONDO:0013172
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id: GO:0097423
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans.","definition_xrefs":["NIF_Subcellular:sao1933817066","PMID:20089910"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"mitochondrion-associated adherens complex","synonyms":[{"name":"MAC","type":"related"},{"name":"mitochondrial adhaerens complex","type":"exact"}],"termid":"GO:0097423"}


id: MONDO:0004970
data:
  {"annotated_genes":["SJAG_00440","SJAG_02231","SJAG_03787","SJAG_01151","SJAG_01970","SJAG_03453","SJAG_02049","SJAG_04067","SJAG_03677","SJAG_01144"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86923],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014937"},{"annotations":[86395],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007256"},{"annotations":[85914],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0003789"},{"annotations":[86533,86532,86534],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007763"},{"annotations":[85634],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012004"},{"annotations":[87054,87053,85611],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008566"}]},"cv_name":"mondo","definition":"A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma.","definition_xrefs":["NCIT:C2852"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carcinoma","termid":"MONDO:0004993"},{"relation_name":"is_a","term_name":"glandular cell neoplasm","termid":"MONDO:0024276"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00440":null,"SJAG_01144":null,"SJAG_01151":null,"SJAG_01970":null,"SJAG_02049":null,"SJAG_02231":null,"SJAG_03453":null,"SJAG_03677":null,"SJAG_03787":null,"SJAG_04067":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"adenocarcinoma","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:D000230","EFO:0000228","ICDO:8140/3","ONCOTREE:ADNOS","CSP:2000-0386","DOID:299","MEDGEN:122","UMLS:C0001418","SCTID:443961001"],"synonyms":[{"name":"ADNOS","type":"related"},{"name":"adenocarcinoma","type":"exact"},{"name":"adenocarcinoma NOS (morphologic abnormality)","type":"exact"},{"name":"adenocarcinoma, malignant","type":"exact"},{"name":"adenocarcinoma, no subtype (morphologic abnormality)","type":"exact"},{"name":"adenocarcinomas","type":"exact"}],"termid":"MONDO:0004970","terms_by_termid":{"MONDO:0003789":null,"MONDO:0007256":null,"MONDO:0007763":null,"MONDO:0008566":null,"MONDO:0012004":null,"MONDO:0014937":null},"xrefs":{"Monarch":{"xref_id":"0004970"}}}


id: PBO:0031175
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-mitotic_catastrophe,_elongated_cell","termid":"PBO:0031175"}


id: GO:0070022
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A homodimeric receptor complex that consists of two TGF-beta receptor monomers.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete transforming growth factor beta receptor complex (obsolete GO:0070022)","synonyms":[{"name":"TGF-beta receptor complex","type":"broad"},{"name":"transforming growth factor beta receptor complex","type":"exact"}],"termid":"GO:0070022"}


id: GO:0007146
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes.","definition_xrefs":["GOC:jl","PMID:9334324"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic DNA recombinase assembly","termid":"GO:0000707"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006281"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006310"}],"interesting_parent_ids":["GO:0007049","GO:0008150","GO:0006259","GO:0044085","GO:0006281","GO:0006310","GO:0065003"],"is_obsolete":false,"name":"meiotic recombination nodule assembly","termid":"GO:0007146"}


id: GO:0031784
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a melatonin receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor binding","termid":"GO:0001664"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005515","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"melatonin receptor binding","synonyms":[{"name":"melatonin receptor ligand","type":"narrow"}],"termid":"GO:0031784"}


id: PBO:0072357
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S26 pseudogene 43","termid":"PBO:0072357"}


id: PBO:0056615
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MYST/Esa1-associated factor 6 pseudogene 1","termid":"PBO:0056615"}


id: PBO:0046226
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin C pseudogene 19","termid":"PBO:0046226"}


id: GO:0042921
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A nuclear receptor-mediated signaling pathway initiated by a glucocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["PMID:15240347"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear receptor-mediated corticosteroid signaling pathway","termid":"GO:0031958"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"nuclear receptor-mediated glucocorticoid signaling pathway","synonyms":[{"name":"glucocorticoid receptor signaling pathway","type":"broad"},{"name":"glucocorticoid receptor signalling pathway","type":"broad"},{"name":"intracellular glucocorticoid receptor signaling pathway","type":"exact"}],"termid":"GO:0042921"}


id: GO:0010114
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.","definition_xrefs":["GOC:mtg_far_red","GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to red or far red light","termid":"GO:0009639"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to red light","synonyms":[{"name":"response to red light stimulus","type":"exact"}],"termid":"GO:0010114"}


id: MONDO:0958085
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare subtype of hemochromatosis characterized by the combination of pathogenic variants in two genes involved in iron metabolism (usually a combination of HFE and non-HFE mutations), where the classical HFE-related hemochromatosis is not enough to fully explain the clinical picture of the patient.","definition_xrefs":["Orphanet:648581"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary hemochromatosis","termid":"MONDO:0006507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"digenic hemochromatosis","secondary_identifiers":["UMLS:C5816744","MEDGEN:1853200"],"termid":"MONDO:0958085","xrefs":{"Monarch":{"xref_id":"0958085"}}}


id: PBO:0053032
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysosomal protein transmembrane 5","termid":"PBO:0053032"}


id: PBO:0090190
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-binding transcription factor Pho7","termid":"PBO:0090190"}


id: GO:1902990
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.","definition_xrefs":["GO_REF:0000060","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"telomere maintenance via semi-conservative replication","termid":"GO:0032201"},{"relation_name":"is_a","term_name":"mitotic cell cycle process","termid":"GO:1903047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0032200"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0006260"}],"interesting_parent_ids":["GO:0006260","GO:0006259","GO:0007049","GO:0008150","GO:0032200"],"is_obsolete":false,"name":"mitotic telomere maintenance via semi-conservative replication","synonyms":[{"name":"equal telomere replication involved in mitotic cell cycle","type":"related"},{"name":"telomeric fork progression involved in mitotic cell cycle","type":"narrow"},{"name":"telomeric replication fork progression involved in mitotic cell cycle","type":"narrow"}],"termid":"GO:1902990"}


id: PBO:0047430
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FCF1 pseudogene 1","termid":"PBO:0047430"}


id: MONDO:1010674
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any thrombopathia in cattle in which the cause of the disease is a mutation in the RASGRP2 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"thrombopathia, non-human animal","termid":"MONDO:1011695"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombopathia, RASGRP2-related, cattle","secondary_identifiers":["OMIA:002433-9913"],"termid":"MONDO:1010674","xrefs":{"Monarch":{"xref_id":"1010674"}}}


id: MONDO:0017029
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Langerhans cell histiocytosis that occurs during adulthood.","definition_xrefs":["NCIT:C114929"],"direct_ancestors":[{"relation_name":"is_a","term_name":"interstitial lung disease specific to adulthood","termid":"MONDO:0017026"},{"relation_name":"is_a","term_name":"Langerhans cell histiocytosis","termid":"MONDO:0018310"},{"relation_name":"is_a","term_name":"lung neoplasm","termid":"MONDO:0021117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"Langerhans cell histiocytosis specific to adulthood","secondary_identifiers":["MEDGEN:859694","UMLS:C3900100","NANDO:2200031","Orphanet:264750"],"synonyms":[{"name":"Langerhans cell granulomatosis specific to adulthood","type":"exact"},{"name":"Langerhans cell histiocytosis","type":"broad"},{"name":"adult Langerhans cell histiocytosis","type":"exact"},{"name":"histiocytosis X specific to adulthood","type":"exact"}],"termid":"MONDO:0017029","xrefs":{"Monarch":{"xref_id":"0017029"}}}


id: GO:0046272
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stilbene metabolic process","termid":"GO:0009810"},{"relation_name":"is_a","term_name":"olefinic compound catabolic process","termid":"GO:0120256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"stilbene catabolic process","synonyms":[{"name":"stilbene breakdown","type":"exact"},{"name":"stilbene catabolism","type":"exact"},{"name":"stilbene degradation","type":"exact"}],"termid":"GO:0046272"}


id: PBO:0073922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 16 member 11","termid":"PBO:0073922"}


id: PBO:0081300
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 81","termid":"PBO:0081300"}


id: GO:1905061
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation.","definition_xrefs":["GOC:BHF","GOC:bc","PMID:24236097","GOC:BHF_miRNA","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cardioblast proliferation","termid":"GO:0003264"},{"relation_name":"is_a","term_name":"negative regulation of cell proliferation involved in heart morphogenesis","termid":"GO:2000137"},{"relation_name":"negatively_regulates","term_name":"cardioblast proliferation","termid":"GO:0003263"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cardioblast proliferation","synonyms":[{"name":"down regulation of cardioblast proliferation","type":"exact"},{"name":"down-regulation of cardioblast proliferation","type":"exact"},{"name":"downregulation of cardioblast proliferation","type":"exact"},{"name":"inhibition of cardioblast proliferation","type":"narrow"}],"termid":"GO:1905061"}


id: GO:0033657
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete disruption by symbiont of host chloroplast part (obsolete GO:0033657)","synonyms":[{"name":"modification by symbiont of host chloroplast part","type":"related"}],"termid":"GO:0033657"}


id: PBO:0054332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1725","termid":"PBO:0054332"}


id: MOD:00976
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass - OBSOLETE because redundant and identical to MOD:01072. Remap to MOD:01072.","definition_xrefs":["DeltaMass:0"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE MOD:00976 potassium salt (obsolete MOD:00976)","termid":"MOD:00976"}


id: FYPO:0008259
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is decreased, and the localizatiion to the endosomal structure is increased. The cell surface refers to the external part of the cell wall and/or plasma membrane.","definition_xrefs":["PMID:22848669"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to cell surface","termid":"FYPO:0008258"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein localization to cell surface with increased localization to endosomal structures","termid":"FYPO:0008259"}


id: PBO:0087424
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit A of the V1 peripheral membrane domain of V-ATPase; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner","termid":"PBO:0087424"}


id: MONDO:0013997
data:
  {"annotated_genes":["SJAG_03249"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86795],"is_not":false,"summary":null,"term":"MONDO:0013997"}]},"cv_name":"mondo","definition":"Focal facial dermal dysplasia type IV (FFDD4) is a rare focal facial dysplasia (FFDD), characterized by congenital isolated preauricular and/or cheek blister scar-like lesions.","definition_xrefs":["Orphanet:398189"],"direct_ancestors":[{"relation_name":"is_a","term_name":"focal facial dermal dysplasia","termid":"MONDO:0018363"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03249":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"focal facial dermal dysplasia type IV","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:17650","OMIM:614974","MEDGEN:767160","UMLS:C3554246"],"synonyms":[{"name":"FFDD type IV","type":"exact"},{"name":"FFDD4","type":"exact"},{"name":"focal Facial dermal dysplasia type 4","type":"exact"},{"name":"focal facial dermal dysplasia 4","type":"exact"},{"name":"focal facial preauricular dysplasia","type":"exact"}],"termid":"MONDO:0013997","terms_by_termid":{"MONDO:0013997":null},"xrefs":{"Monarch":{"xref_id":"0013997"}}}


id: PR:O42648
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- nht1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42648"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HMG box-containing protein C10F6.08c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC10F6.08c","synonyms":[{"name":"Spom972h-nht1","type":"exact"}],"termid":"PR:O42648"}


id: PATO:0001813
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in a bearer by virtue of the bearer's lack elastic tension that facilitate response to stimuli.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tonicity","termid":"PATO:0001439"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atonicity","termid":"PATO:0001813"}


id: GO:0046188
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methane metabolic process","termid":"GO:0015947"},{"relation_name":"is_a","term_name":"alkane catabolic process","termid":"GO:0043448"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"methane catabolic process","synonyms":[{"name":"methane breakdown","type":"exact"},{"name":"methane catabolism","type":"exact"},{"name":"methane degradation","type":"exact"}],"termid":"GO:0046188"}


id: PBO:0003333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome component beta 7 (predicted)","termid":"PBO:0003333"}


id: MONDO:0018358
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"secondary neonatal autoimmune disease","termid":"MONDO:0018356"},{"relation_name":"is_a","term_name":"autoimmune hemolytic anemia","termid":"MONDO:0020108"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0002280","MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"neonatal autoimmune hemolytic anemia","secondary_identifiers":["MEDGEN:1662969","Orphanet:398109","UMLS:C4751517","GARD:21645"],"synonyms":[{"name":"neonatal AHA","type":"exact"},{"name":"neonatal AIHA","type":"exact"}],"termid":"MONDO:0018358","xrefs":{"Monarch":{"xref_id":"0018358"}}}


id: MONDO:0006140
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, extremely well differentiated cervical mucinous adenocarcinoma in which most of the neoplastic glands cannot be distinguished from the normal endocervical glands.","definition_xrefs":["NCIT:C40206"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cervical mucinous adenocarcinoma","termid":"MONDO:0002742"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"cervical mucinous adenocarcinoma, minimal deviation variant","secondary_identifiers":["MEDGEN:273125","EFO:1000169","UMLS:C1516423","DOID:6627"],"synonyms":[{"name":"cervical adenoma malignum","type":"exact"},{"name":"cervical mucinous adenocarcinoma, minimal deviation type","type":"exact"},{"name":"cervical mucinous adenocarcinoma, minimal deviation variant","type":"exact"}],"termid":"MONDO:0006140","xrefs":{"Monarch":{"xref_id":"0006140"}}}


id: MONDO:0021289
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A in situ carcinoma that involves the caecum.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colon carcinoma in situ","termid":"MONDO:0004663"},{"relation_name":"is_a","term_name":"cecum carcinoma","termid":"MONDO:0006029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"carcinoma in situ of cecum","secondary_identifiers":["SCTID:92559007","NCIT:C4594","UMLS:C0347126","MEDGEN:83854"],"synonyms":[{"name":"caecum carcinoma in situ","type":"exact"},{"name":"caecum in situ carcinoma","type":"exact"},{"name":"carcinoma in situ of caecum","type":"exact"},{"name":"carcinoma in situ of the cecum","type":"exact"},{"name":"cecum carcinoma in situ","type":"exact"},{"name":"cecum carcinoma in situ aJCC v6","type":"exact"},{"name":"cecum carcinoma in situ aJCC v7","type":"exact"},{"name":"stage 0 caecum carcinoma","type":"exact"},{"name":"stage 0 cecum carcinoma","type":"exact"}],"termid":"MONDO:0021289","xrefs":{"Monarch":{"xref_id":"0021289"}}}


id: PBO:0029327
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_histone_H2A_phosphorylation_during_mitotic_S_phase","termid":"PBO:0029327"}


id: PBO:0017021
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"box H/ACA small nucleolar RNA 20/snR35","termid":"PBO:0017021"}


id: PBO:0088564
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Golgi alpha-1,2-mannosyltransferase Omh2","termid":"PBO:0088564"}


id: PR:Q9P7J4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mft1 gene.","definition_xrefs":["UniProtKB:Q9P7J4","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THO complex subunit mft1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC24B10.11c","synonyms":[{"name":"Spom972h-mft1","type":"exact"}],"termid":"PR:Q9P7J4"}


id: MONDO:0030981
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"severe combined immunodeficiency","termid":"MONDO:0015974"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 79","secondary_identifiers":["UMLS:C5543220","MEDGEN:1783683","OMIM:619238","DOID:0112277","GARD:9523"],"synonyms":[{"name":"CD4 Deficiency","type":"exact"},{"name":"IMD79","type":"exact"},{"name":"immunodeficiency 79","type":"exact"}],"termid":"MONDO:0030981","xrefs":{"Monarch":{"xref_id":"0030981"}}}


id: MONDO:0006671
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with bacteria of the genus bacteroides.","definition_xrefs":["MESH:D001442"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Bacteroidaceae infectious disease","termid":"MONDO:0006705"},{"relation_name":"is_a","term_name":"anaerobic bacteria infectious disease","termid":"MONDO:0024389"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Bacteroides infectious disease","secondary_identifiers":["EFO:1000832","ICD9:041.84","SCTID:2918000","UMLS:C0004669","MEDGEN:2164"],"synonyms":[{"name":"Bacteroides caused disease or disorder","type":"exact"},{"name":"Bacteroides disease or disorder","type":"exact"},{"name":"Bacteroides infection","type":"related"},{"name":"infection caused by Bacteroides","type":"related"},{"name":"infection due to Bacteroides","type":"exact"},{"name":"infection, Bacteroides","type":"related"},{"name":"infections, Bacteroides","type":"related"}],"termid":"MONDO:0006671","xrefs":{"Monarch":{"xref_id":"0006671"}}}


id: PBO:0017926
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase assembly protein Shy1 (predicted)","termid":"PBO:0017926"}


id: GO:0015147
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.","definition_xrefs":["GOC:mtg_transport","ISBN:0198506732","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arabinose transmembrane transporter activity","termid":"GO:0042900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"L-arabinose transmembrane transporter activity","synonyms":[{"name":"L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity","type":"narrow"}],"termid":"GO:0015147"}


id: FYPO:0002840
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to chromosome during vegetative growth","termid":"FYPO:0002838"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000138","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"increased protein localization to chromosome during vegetative growth","synonyms":[{"name":"increased protein localisation to chromosome during vegetative growth","type":"exact"},{"name":"increased protein localization to chromosome during mitotic cell cycle","type":"related"}],"termid":"FYPO:0002840"}


id: GO:0018664
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: benzoate + H+ + NADPH + O2 = 4-hydroxybenzoate + H2O + NADP+.","definition_xrefs":["EC:1.14.14.92","RHEA:18033"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"benzoate 4-monooxygenase activity","secondary_identifiers":["UM-BBD_reactionID:r0623","MetaCyc:BENZOATE-4-MONOOXYGENASE-RXN","KEGG_REACTION:R01295"],"synonyms":[{"name":"4-hydroxybenzoic hydroxylase activity","type":"exact"},{"name":"benzoate 4-hydroxylase activity","type":"related"},{"name":"benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)","type":"related"},{"name":"benzoate-p-hydroxylase activity","type":"related"},{"name":"benzoate-para-hydroxylase activity","type":"related"},{"name":"benzoic 4-hydroxylase activity","type":"related"},{"name":"benzoic acid 4-hydroxylase activity","type":"related"},{"name":"p-hydroxybenzoate hydroxylase activity","type":"related"}],"termid":"GO:0018664"}


id: MONDO:0014120
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"muscular dystrophy-dystroglycanopathy, type A","termid":"MONDO:0000171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0005336"],"is_obsolete":false,"name":"muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A13","secondary_identifiers":["GARD:15938","OMIM:615287","DOID:0111238","MEDGEN:815372","UMLS:C3809042"],"synonyms":[{"name":"MDDGA13","type":"related"},{"name":"Walker-Warburg syndrome or muscle-eye-brain disease, B3Gnt1-related","type":"related"},{"name":"muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 13","type":"related"}],"termid":"MONDO:0014120","xrefs":{"Monarch":{"xref_id":"0014120"}}}


id: PBO:0049233
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRM5 antisense RNA 1","termid":"PBO:0049233"}


id: FYPO:0008027
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A regulation phenotype observed in the vegetative growth phase of the life cycle in which the rate of acid phosphatase activation during phosphate starvation is increased.","definition_xrefs":["PMID:35012333"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal regulation of catalytic activity","termid":"FYPO:0004916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"increased rate of acid phosphatase activation during phosphate starvation","synonyms":[{"name":"increased acid phosphatase kinetics","type":"exact"}],"termid":"FYPO:0008027"}


id: GO:1903442
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.","definition_xrefs":["GO_REF:0000071","PMID:23232760","GOC:sl","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to fatty acid","termid":"GO:0070542"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to lipoic acid","termid":"GO:1903442"}


id: PBO:0057896
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3199-1","termid":"PBO:0057896"}


id: MONDO:1011214
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Coloboma that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coloboma, non-human animal","termid":"MONDO:1010319"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coloboma, dog","secondary_identifiers":["OMIA:000219-9615"],"termid":"MONDO:1011214","xrefs":{"Monarch":{"xref_id":"1011214"}}}


id: GO:0080191
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem.","definition_xrefs":["PO:0025414","JSTOR:4354165","PO:0025004"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lateral growth","termid":"GO:0080190"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"secondary thickening","termid":"GO:0080191"}


id: GO:0052522
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction (obsolete GO:0052522)","synonyms":[{"name":"activation by organism of phagocytosis in other organism during symbiotic interaction","type":"narrow"},{"name":"positive regulation by organism of phagocytosis in other organism during symbiotic interaction","type":"related"},{"name":"stimulation by organism of phagocytosis in other organism during symbiotic interaction","type":"narrow"},{"name":"up regulation by organism of phagocytosis in other organism during symbiotic interaction","type":"related"},{"name":"up-regulation by organism of phagocytosis in other organism during symbiotic interaction","type":"related"},{"name":"upregulation by organism of phagocytosis in other organism during symbiotic interaction","type":"related"}],"termid":"GO:0052522"}


id: GO:0006491
data:
  {"annotated_genes":["SJAG_03535","SJAG_04571","SJAG_03280"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76499,78170,113566],"is_not":false,"summary":null,"term":"GO:0006491"}]},"cv_name":"biological_process","definition":"The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.","definition_xrefs":["ISBN:0879695595","PMID:12736198"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycoprotein metabolic process","termid":"GO:0009100"}],"gene_count":3,"genes_by_uniquename":{"SJAG_03280":null,"SJAG_03535":null,"SJAG_04571":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"N-glycan processing","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0006492"],"synonyms":[{"name":"N-linked glycoprotein maturation","type":"exact"},{"name":"glycoprotein trimming involved in glycoprotein maturation","type":"narrow"}],"termid":"GO:0006491","terms_by_termid":{"GO:0006491":null}}


id: GO:0045751
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of Toll signaling pathway","termid":"GO:0008592"},{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"negatively_regulates","term_name":"Toll signaling pathway","termid":"GO:0008063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of Toll signaling pathway","synonyms":[{"name":"down regulation of Toll signaling pathway","type":"exact"},{"name":"down-regulation of Toll signaling pathway","type":"exact"},{"name":"downregulation of Toll signaling pathway","type":"exact"},{"name":"inhibition of Toll signaling pathway","type":"narrow"},{"name":"negative regulation of Tl signaling pathway","type":"exact"},{"name":"negative regulation of Tl signalling pathway","type":"exact"}],"termid":"GO:0045751"}


id: PBO:0088731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutathione-specific gamma-glutamylcyclotransferase Ggg1","termid":"PBO:0088731"}


id: PR:P40233
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cki1 gene.","definition_xrefs":["UniProtKB:P40233","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"casein kinase I homolog 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1347.06c","synonyms":[{"name":"SPBC1347.06c","type":"related"},{"name":"Spom972h-cki1","type":"exact"}],"termid":"PR:P40233"}


id: PBO:0074985
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 114-27","termid":"PBO:0074985"}


id: GO:0072436
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint.","definition_xrefs":["GOC:mtg_cell_cycle"],"gene_count":0,"genotype_count":0,"name":"obsolete detection of stimulus involved in DNA replication checkpoint (obsolete GO:0072436)","synonyms":[{"name":"DNA replication checkpoint sensor mechanism","type":"related"},{"name":"DNA replication checkpoint sensor process","type":"related"},{"name":"sensing involved in DNA replication checkpoint","type":"related"}],"termid":"GO:0072436"}


id: SO:0001012
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A DNA sequence with catalytic activity.","definition_xrefs":["SO:cb"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"enzymatic","termid":"SO:0001185"},{"relation_name":"is_a","term_name":"oligo","termid":"SO:0000696"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAzyme","synonyms":[{"name":"DNA enzyme","type":"exact"},{"name":"catalytic DNA","type":"exact"},{"name":"deoxyribozyme","type":"related"}],"termid":"SO:0001012"}


id: PBO:0075504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spermatogenesis associated serine rich 2","termid":"PBO:0075504"}


id: GO:0019637
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id: PBO:0071521
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L34 pseudogene 24","termid":"PBO:0071521"}


id: PBO:0039772
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AQP5 and AQP2 antisense RNA 2","termid":"PBO:0039772"}


id: PBO:0056028
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipolysis stimulated lipoprotein receptor","termid":"PBO:0056028"}


id: PBO:0059939
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND2 pseudogene 25","termid":"PBO:0059939"}


id: MONDO:0958277
data:
  {"annotated_genes":["SJAG_03536"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86873],"is_not":false,"summary":null,"term":"MONDO:0958277"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03536":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0006025"],"is_obsolete":false,"name":"hearing loss, autosomal recessive 123","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:620745","UMLS:C5935588","MEDGEN:1861332"],"synonyms":[{"name":"deafness, autosomal recessive 123","type":"narrow"}],"termid":"MONDO:0958277","terms_by_termid":{"MONDO:0958277":null},"xrefs":{"Monarch":{"xref_id":"0958277"}}}


id: PBO:0039271
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aldolase, fructose-bisphosphate C","termid":"PBO:0039271"}


id: PATO:0000784
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000784 excretory function value (obsolete PATO:0000784)","termid":"PATO:0000784"}


id: MOD:01648
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively removes or replaces an L-tryptophan.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-tryptophan residue","termid":"MOD:00918"},{"relation_name":"is_a","term_name":"natural, standard, encoded residue removal","termid":"MOD:01651"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-tryptophan removal","termid":"MOD:01648"}


id: PBO:0004646
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acyl-CoA thioesterase (predicted)","termid":"PBO:0004646"}


id: FYPO:0007377
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A  cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the medial cortex is observed there during interphase of the mitotic cell cycle.","definition_xrefs":["PMID:9679144","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein mislocalized to medial cortex during vegetative growth","termid":"FYPO:0003390"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0001320","FYPO:0005447","FYPO:0000138"],"is_obsolete":false,"name":"protein mislocalized to medial cortex during mitotic interphase","synonyms":[{"name":"ectopic protein localization to medial cortex during mitotic interphase","type":"exact"},{"name":"protein mislocalised to medial cortex during mitotic interphase during vegetative growth","type":"exact"},{"name":"protein mislocalized to medial cortex during interphase of mitotic cell cycle","type":"exact"}],"termid":"FYPO:0007377"}


id: MONDO:0971001
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 121 with autoinflammation","secondary_identifiers":["UMLS:C5935616","OMIM:620807","MEDGEN:1857174"],"termid":"MONDO:0971001","xrefs":{"Monarch":{"xref_id":"0971001"}}}


id: GO:0048577
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.","definition_xrefs":["ISBN:0697037754","ISBN:0582015952","GOC:jid","GOC:pj","ISBN:0709408862"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of post-embryonic development","termid":"GO:0048581"},{"relation_name":"is_a","term_name":"negative regulation of response to stimulus","termid":"GO:0048585"},{"relation_name":"is_a","term_name":"regulation of short-day photoperiodism, flowering","termid":"GO:0048587"},{"relation_name":"negatively_regulates","term_name":"short-day photoperiodism, flowering","termid":"GO:0048575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of short-day photoperiodism, flowering","synonyms":[{"name":"down regulation of short-day photoperiodism, flowering","type":"exact"},{"name":"down-regulation of short-day photoperiodism, flowering","type":"exact"},{"name":"downregulation of short-day photoperiodism, flowering","type":"exact"},{"name":"inhibition of short-day photoperiodism, flowering","type":"narrow"}],"termid":"GO:0048577"}


id: PBO:0090375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ergothioneine biosynthesis methyltransferase Egt2","termid":"PBO:0090375"}


id: GO:0023017
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which a signal is conveyed via a diffusible molecule.","definition_xrefs":["GOC:mtg_signal"],"gene_count":0,"genotype_count":0,"name":"obsolete signal transmission via diffusible molecule (obsolete GO:0023017)","synonyms":[{"name":"signal transmission via diffusible molecule","type":"exact"},{"name":"signaling via diffusible mediator","type":"exact"}],"termid":"GO:0023017"}


id: MONDO:0030048
data:
  {"annotated_genes":["SJAG_04944"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85170],"is_not":false,"summary":null,"term":"MONDO:0030048"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"CPOX-related hereditary coproporphyria","termid":"MONDO:0800180"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04944":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0019142"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066","MONDO:0019142"],"is_obsolete":false,"name":"harderoporphyria","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:618892","MESH:C562816","Orphanet:659672","UMLS:C0342859","icd11.foundation:1664486132","MEDGEN:137981"],"synonyms":[{"name":"HARDEROPORPHYRIA","type":"exact"},{"name":"HARPO","type":"exact"},{"name":"harderoporphyria","type":"exact"}],"termid":"MONDO:0030048","terms_by_termid":{"MONDO:0030048":null},"xrefs":{"Monarch":{"xref_id":"0030048"}}}


id: PR:O94410
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug163 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94410"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 163 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1620.03","synonyms":[{"name":"Spom972h-mug163","type":"exact"}],"termid":"PR:O94410"}


id: PR:P49373
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- tfs1 gene.","definition_xrefs":["UniProtKB:P49373","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription elongation factor S-II (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC20H4.03c","synonyms":[{"name":"Spom972h-tfs1","type":"exact"},{"name":"TFIIS (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P49373"}


id: MONDO:0044884
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A primary lymphoma that affects the tonsil and the bulk of the tumor is in this anatomic area. The majority of cases are B-cell non-Hodgkin lymphomas.","definition_xrefs":["NCIT:C5918"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gastrointestinal lymphoma","termid":"MONDO:0004699"},{"relation_name":"is_a","term_name":"spleen cancer","termid":"MONDO:0005966"},{"relation_name":"is_a","term_name":"tonsil cancer","termid":"MONDO:0006998"},{"relation_name":"is_a","term_name":"MALT lymphoma","termid":"MONDO:0007650"},{"relation_name":"is_a","term_name":"hereditary otorhinolaryngologic disease","termid":"MONDO:0018751"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004335","MONDO:0004992","MONDO:0005570"],"is_obsolete":false,"name":"tonsillar lymphoma","secondary_identifiers":["MEDGEN:234432","UMLS:C1336765"],"synonyms":[{"name":"Primary tonsillar lymphoma","type":"exact"},{"name":"lymphoma of the tonsil","type":"exact"},{"name":"lymphoma of tonsil","type":"exact"},{"name":"tonsil lymphoma","type":"exact"},{"name":"tonsillar lymphoma","type":"exact"}],"termid":"MONDO:0044884","xrefs":{"Monarch":{"xref_id":"0044884"}}}


id: PBO:0047871
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, folic acid type, rare, fra(2)(q22.3)","termid":"PBO:0047871"}


id: MONDO:0011124
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare primary bone dysplasia disorder characterized by the association of dental anomalies (oligodontia with pointed incisors) and generalized platyspondyly with epiphyseal and metaphyseal involvement. Thin tapering fingers and accentuated palmar creases are additional features.","definition_xrefs":["Orphanet:168451"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"spondyloepiphyseal dysplasia","termid":"MONDO:0016761"},{"relation_name":"is_a","term_name":"spondyloepimetaphyseal dysplasia","termid":"MONDO:0100510"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"spondyloepimetaphyseal dysplasia-abnormal dentition syndrome","secondary_identifiers":["OMIM:601668","GARD:17030","MEDGEN:356550","MESH:C566644","UMLS:C1866507"],"synonyms":[{"name":"SEMDAD","type":"related"},{"name":"spondyloepimetaphyseal dysplasia with abnormal dentition","type":"related"}],"termid":"MONDO:0011124","xrefs":{"Monarch":{"xref_id":"0011124"}}}


id: PR:C6Y4A4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC688.16 gene.","definition_xrefs":["UniProtKB:C6Y4A4","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized membrane protein C688.16 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC688.16","synonyms":[{"name":"Spom972h-SPAC688.16","type":"exact"}],"termid":"PR:C6Y4A4"}


id: PBO:0108544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clr6 histone deacetylase complex MRG family subunit Alp13","termid":"PBO:0108544"}


id: GO:0016753
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acyltransferase activity","termid":"GO:0008374"},{"relation_name":"is_a","term_name":"sinapoyltransferase activity","termid":"GO:0016752"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016746","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"O-sinapoyltransferase activity","termid":"GO:0016753"}


id: PBO:0111934
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin family 6","termid":"PBO:0111934"}


id: PBO:0083196
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene HIR3; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching","termid":"PBO:0083196"}


id: MONDO:0033479
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant cerebellar ataxia","termid":"MONDO:0020380"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0002039","MONDO:0005559"],"is_obsolete":false,"name":"spinocerebellar ataxia 44","secondary_identifiers":["UMLS:C4521563","DOID:0080286","Orphanet:631095","MEDGEN:1611168","OMIM:617691"],"synonyms":[{"name":"SCA44","type":"related"},{"name":"spinocerebellar ataxia 44","type":"exact"}],"termid":"MONDO:0033479","xrefs":{"Monarch":{"xref_id":"0033479"}}}


id: PR:Q9USJ5
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- hem12 gene.","definition_xrefs":["UniProtKB:Q9USJ5","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uroporphyrinogen decarboxylase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC4B3.05c","synonyms":[{"name":"Spom972h-hem12","type":"exact"},{"name":"UPD (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"URO-D (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9USJ5"}


id: GO:0080077
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule.","definition_xrefs":["PMID:19077165"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-methyltransferase activity","termid":"GO:0008171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016741","GO:0016740"],"is_obsolete":false,"name":"trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity","termid":"GO:0080077"}


id: PBO:0005301
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy and CVT pathway serine/threonine protein kinase Atg1","termid":"PBO:0005301"}


id: MONDO:0009668
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Multiple pterygium syndrome lethal type is a very rare genetic condition affecting the skin, muscles and skeleton. It is characterized by minor facial abnormalities, prenatal growth deficiency, spine defects, joint contractures, and webbing (pterygia)of the neck, elbows, back of the knees, armpits, and fingers. Fetuses with this condition are usually not born. Some of the prenatal complications include cystic hygroma, hydrops, diaphragmatic hernia, polyhydramnios, underdevelopment of the heart and lungs, microcephaly, bone fusions, joint dislocations, spinal fusion, andbone fractures. Both X-linked and autosomal recessive inheritance have been proposed. Mutations in the CHRNG, CHRNA1, and CHRND genes have been found to cause this condition.","definition_xrefs":["GARD:0003834"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"multiple pterygium syndrome","termid":"MONDO:0017415"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lethal multiple pterygium syndrome","secondary_identifiers":["SCTID:60192008","UMLS:C1854678","Orphanet:33108","GARD:3834","OMIM:253290","MEDGEN:381473","ICD9:759.89","NCIT:C101038"],"synonyms":[{"name":"LMPS","type":"exact"},{"name":"autosomal recessive lethal multiple pterygium syndrome","type":"exact"},{"name":"lethal multiple pterygium syndrome","type":"exact"},{"name":"multiple pterygium syndrome lethal type","type":"related"},{"name":"multiple pterygium syndrome, lethal type","type":"related"},{"name":"pterygium syndrome multiple lethal type","type":"related"},{"name":"pterygium syndrome, multiple, lethal type","type":"related"}],"termid":"MONDO:0009668","xrefs":{"Monarch":{"xref_id":"0009668"}}}


id: PR:Q9Y806
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC146.04 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9Y806"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FAD-linked sulfhydryl oxidase erv2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC146.04","synonyms":[{"name":"Spom972h-SPBC146.04","type":"exact"}],"termid":"PR:Q9Y806"}


id: GO:0043835
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reactions: uracil + H2O + acceptor = barbiturate + reduced acceptor; and thymine + H2O + acceptor = 5-methylbarbiturate + reduced acceptor.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete uracil/thymine dehydrogenase activity (obsolete GO:0043835)","synonyms":[{"name":"uracil/thymine dehydrogenase activity","type":"exact"},{"name":"uracil:acceptor oxidoreductase activity","type":"narrow"}],"termid":"GO:0043835"}


id: MONDO:0012484
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of prosopagnosia (disease) that is caused by an inherited modification of the individual's genome.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prosopagnosia","termid":"MONDO:0003227"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prosopagnosia, hereditary","secondary_identifiers":["UMLS:C2931455","MEDGEN:419809","OMIM:610382","MESH:C537242"],"synonyms":[{"name":"congenital prosopagnosia","type":"related"},{"name":"developmental prosopagnosia","type":"related"},{"name":"face blindness","type":"related"},{"name":"hereditary prosopagnosia","type":"related"},{"name":"hereditary prosopagnosia (disease)","type":"exact"},{"name":"prosopagnosia, congenital","type":"related"},{"name":"prosopagnosia, developmental","type":"related"},{"name":"prosopagnosia, hereditary","type":"exact"}],"termid":"MONDO:0012484","xrefs":{"Monarch":{"xref_id":"0012484"}}}


id: PBO:0111784
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zf-UBP type","termid":"PBO:0111784"}


id: PBO:0046819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FA core complex associated protein 20","termid":"PBO:0046819"}


id: GO:0002120
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Aggressive behavior involving attack on prey by a predator.","definition_xrefs":["GOC:hjd"],"gene_count":0,"genotype_count":0,"name":"obsolete predatory behavior (obsolete GO:0002120)","synonyms":[{"name":"predatory aggression","type":"exact"},{"name":"predatory aggressive behavior","type":"exact"}],"termid":"GO:0002120"}


id: GO:2000048
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell-cell adhesion","termid":"GO:0022408"},{"relation_name":"is_a","term_name":"regulation of cell-cell adhesion mediated by cadherin","termid":"GO:2000047"},{"relation_name":"negatively_regulates","term_name":"cell-cell adhesion mediated by cadherin","termid":"GO:0044331"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell-cell adhesion mediated by cadherin","termid":"GO:2000048"}


id: PBO:0030122
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_RNA_level_during_cellular_response_to_zinc_ion","termid":"PBO:0030122"}


id: PBO:0040137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activating signal cointegrator 1 complex subunit 3","termid":"PBO:0040137"}


id: PBO:0116281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitotic spindle midzone-localized microtubule bundling protein; microtubule-associated protein (MAP) family member; required for anaphase spindle elongation and stabilization; selectively increases the lifetime of antiparallel microtubule overlaps; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate; relative distribution to microtubules decreases upon DNA replication stress","termid":"PBO:0116281"}


id: FYPO:0007225
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is normal (i.e. indistinguishable from wild type). Small RNA-mediated heterochromatin assembly results in transcriptional silencing.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal chromatin silencing","termid":"FYPO:0002335"},{"relation_name":"is_a","term_name":"normal cellular component organization","termid":"FYPO:0006003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal heterochromatin assembly by small RNA","synonyms":[{"name":"normal RNAi-mediated chromatin silencing","type":"exact"},{"name":"normal chromatin silencing by small RNA","type":"exact"},{"name":"normal heterochromatin assembly by small RNA during mitotic cell cycle","type":"related"},{"name":"normal heterochromatin assembly by small RNA during vegetative growth","type":"exact"}],"termid":"FYPO:0007225"}


id: PBO:0084380
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation; regulated by nonsense-mediated mRNA decay pathway","termid":"PBO:0084380"}


id: PBO:0056646
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit 15 pseudogene 7","termid":"PBO:0056646"}


id: PBO:0038328
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-obligate_parasite_of","termid":"PBO:0038328"}


id: PBO:0043174
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CIR1 pseudogene 1","termid":"PBO:0043174"}


id: GO:0005075
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete pathway-specific SMAD protein (obsolete GO:0005075)","synonyms":[{"name":"pathway-specific SMAD protein","type":"exact"}],"termid":"GO:0005075"}


id: GO:0052179
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete metabolism by symbiont of host cell wall pectin (obsolete GO:0052179)","synonyms":[{"name":"metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction","type":"narrow"}],"termid":"GO:0052179"}


id: PR:O74879
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A nucleolar protein 10 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04196","PANTHER:PTHR14927:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein enp2 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC330.09","secondary_identifiers":["UniProtKB:O74879"],"synonyms":[{"name":"Spom972h-NOL10","type":"exact"}],"termid":"PR:O74879"}


id: GO:0008767
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.","definition_xrefs":["EC:5.4.99.9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular transferase activity","termid":"GO:0016866"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016853","GO:0003824"],"is_obsolete":false,"name":"UDP-galactopyranose mutase activity","secondary_identifiers":["MetaCyc:GALPMUT-RXN","RHEA:24132"],"synonyms":[{"name":"UDP-D-galactopyranose furanomutase activity","type":"related"},{"name":"UDPgalactopyranose mutase activity","type":"related"}],"termid":"GO:0008767"}


id: SO:0002233
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A chromosomal locus where complementary lncRNA and associated proteins accumulate at the corresponding lncRNA gene loci to tether homologous chromosome during chromosome pairing at meiosis I.","definition_xrefs":["PMID:22582262","PMID:31811152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"binding_site","termid":"SO:0000409"},{"relation_name":"member_of","term_name":"chromosome_part","termid":"SO:0000830"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homologous_chromosome_recognition_and_pairing_locus","synonyms":[{"name":"homologous chromosome recognition and pairing locus","type":"exact"}],"termid":"SO:0002233"}


id: MONDO:0019212
data:
  {"annotated_genes":["SJAG_00580","SJAG_03349","SJAG_03352","SJAG_01474","SJAG_04865"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86854,86853],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008293"},{"annotations":[85902],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013868"},{"annotations":[85765,85764],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014713"}]},"cv_name":"mondo","definition":"Disseminated superficial actinic porokeratosis (DSAP) is the most common form of porokeratosis characterized by the presence of several small annular plaques with a distinctive keratotic rim found most commonly on sun-exposed areas of the skin, particularly the extremities.","definition_xrefs":["Orphanet:79152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"porokeratosis","termid":"MONDO:0006602"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00580":null,"SJAG_01474":null,"SJAG_03349":null,"SJAG_03352":null,"SJAG_04865":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"disseminated superficial actinic porokeratosis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:120561","GARD:10983","icd11.foundation:1828294192","ICD9:692.75","SCTID:41495000","UMLS:C0265970"],"termid":"MONDO:0019212","terms_by_termid":{"MONDO:0008293":null,"MONDO:0013868":null,"MONDO:0014713":null},"xrefs":{"Monarch":{"xref_id":"0019212"}}}


id: PBO:0004887
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cdc48-Ufd1-Npl4 complex component Ufd1 (predicted)","termid":"PBO:0004887"}


id: MONDO:0002497
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete food allergy (obsolete MONDO:0002497)","termid":"MONDO:0002497","xrefs":{"Monarch":{"xref_id":"0002497"}}}


id: GO:0072322
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.","definition_xrefs":["PMID:20378773","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein transport","termid":"GO:0015031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"protein transport across periplasmic space","secondary_identifiers":["GO:0072323"],"synonyms":[{"name":"chaperone-mediated protein transport across periplasmic space","type":"narrow"}],"termid":"GO:0072322"}


id: PBO:0062500
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 8 subfamily F member 1 pseudogene","termid":"PBO:0062500"}


id: PBO:0029130
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_DNA_recombination_at_mating_type_locus","termid":"PBO:0029130"}


id: GO:0021836
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.","definition_xrefs":["GOC:jid","GOC:cls","GOC:dgh","PMID:12626695","GO_REF:0000021","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative chemotaxis","termid":"GO:0050919"},{"relation_name":"part_of","term_name":"postnatal olfactory bulb interneuron migration","termid":"GO:0021827"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chemorepulsion involved in postnatal olfactory bulb interneuron migration","synonyms":[{"name":"negative chemotaxis involved in postnatal olfactory bulb interneuron migration","type":"exact"}],"termid":"GO:0021836"}


id: MONDO:1012030
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"bleeding disorder, non-human animal","termid":"MONDO:1011685"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bleeding disorder, cattle","secondary_identifiers":["OMIA:000113-9913","OMIA:000112-9913"],"synonyms":[{"name":"bleeding diathesis, cattle","type":"exact"}],"termid":"MONDO:1012030","xrefs":{"Monarch":{"xref_id":"1012030"}}}


id: PBO:0082727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the Rix1 complex and possibly pre-replicative complexes; required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-replicative complex (pre-RC) formation and maintenance during DNA replication licensing; relocalizes to the cytosol in response to hypoxia; essential gene","termid":"PBO:0082727"}


id: PBO:0053982
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1298","termid":"PBO:0053982"}


id: PBO:0042143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine ligand 3 pseudogene 1","termid":"PBO:0042143"}


id: FYPO:0000296
data:
  {"alleles_by_uniquename":{"SJAG_01143:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01143","name":"mid1delta","uniquename":"SJAG_01143:allele-1"},"SJAG_02392:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02392","name":"pom1delta","uniquename":"SJAG_02392:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"},"SJAG_03596:allele-1":{"allele_type":"amino_acid_mutation","description":"L264P,P442T","gene_uniquename":"SJAG_03596","name":"cdc15-A","uniquename":"SJAG_03596:allele-1"},"SJAG_04280:allele-2":{"allele_type":"amino_acid_mutation","description":"T582G","gene_uniquename":"SJAG_04280","name":"wee1-as8","uniquename":"SJAG_04280:allele-2"},"SJAG_04522:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04522","name":"rga4delta","uniquename":"SJAG_04522:allele-1"},"SJAG_04703:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04703","name":"for3delta","uniquename":"SJAG_04703:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"multi_locus_phenotype":[{"annotations":[119026],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000231"},{"annotations":[119031],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000729"},{"annotations":[119188],"is_not":false,"rel_names":["output_of"],"summary":null,"term":"FYPO:0001369"}],"single_locus_phenotype":[{"annotations":[119019],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000231"},{"annotations":[119192],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000198"},{"annotations":[118956,119174],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0002998"},{"annotations":[119425],"is_not":false,"rel_names":["output_of"],"summary":null,"term":"FYPO:0003315"},{"annotations":[119052],"is_not":false,"rel_names":["output_of"],"summary":null,"term":"FYPO:0002026"},{"annotations":[119020,119122],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000729"},{"annotations":[119189],"is_not":false,"rel_names":["output_of"],"summary":null,"term":"FYPO:0001369"}]},"cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype that affects the organization of the actin cytoskeleton. Actin cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and associated proteins.","definition_xrefs":["GO:0030036","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoskeleton organization phenotype","termid":"FYPO:0000295"}],"gene_count":7,"genes_by_uniquename":{"SJAG_01143":null,"SJAG_02392":null,"SJAG_02592":null,"SJAG_03596":null,"SJAG_04280":null,"SJAG_04522":null,"SJAG_04703":null},"genotype_count":10,"genotypes_by_uniquename":{"cdc15-A-L264P,P442T-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"cdc15-A(L264P,P442T aa)","display_uniquename":"cdc15-A-L264P,P442T-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03596:allele-1","expression":"Not assayed or wild type"}]}]},"cdc15-A-L264P,P442T-amino_acid_mutation-expression-not_assayed_or_wild_type__mid1delta":{"display_name":"cdc15-A(L264P,P442T aa) mid1delta","display_uniquename":"cdc15-A-L264P,P442T-amino_acid_mutation-expression-not_assayed_or_wild_type__mid1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03596:allele-1","expression":"Not assayed or wild type"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]}]},"for3delta":{"display_name":"for3delta","display_uniquename":"for3delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04703:allele-1","expression":"Null"}]}]},"mid1delta":{"display_name":"mid1delta","display_uniquename":"mid1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]}]},"mid1delta__pom1delta":{"display_name":"mid1delta pom1delta","display_uniquename":"mid1delta__pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]},"pom1delta":{"display_name":"pom1delta","display_uniquename":"pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]},"rga4delta":{"display_name":"rga4delta","display_uniquename":"rga4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]}]},"rga4delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"rga4delta wee1-as8(T582G aa)","display_uniquename":"rga4delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]},"sty1delta":{"display_name":"sty1delta","display_uniquename":"sty1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02592:allele-1","expression":"Null"}]}]},"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"wee1-as8(T582G aa)","display_uniquename":"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002"],"is_obsolete":false,"multi_locus_annotated_genes":["SJAG_03596","SJAG_04280","SJAG_02392","SJAG_04522","SJAG_01143"],"name":"actin cytoskeleton organization phenotype","references_by_uniquename":{"PMID:25866389":null,"PMID:27059155":null,"PMID:30664646":null,"PMID:30726171":null,"PMID:32915139":null,"PMID:33791858":null},"single_locus_annotated_genes":["SJAG_04280","SJAG_03596","SJAG_02592","SJAG_04703","SJAG_02392","SJAG_01143","SJAG_04522"],"single_locus_genotype_uniquenames":["rga4delta","pom1delta","wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","cdc15-A-L264P,P442T-amino_acid_mutation-expression-not_assayed_or_wild_type","sty1delta","for3delta","mid1delta"],"synonyms":[{"name":"actin cytoskeleton organisation phenotype","type":"exact"},{"name":"actin cytoskeleton organization phenotype during mitotic cell cycle","type":"related"},{"name":"actin cytoskeleton organization phenotype during vegetative growth","type":"exact"},{"name":"fission yeast actin cytoskeleton organization phenotype","type":"exact"}],"termid":"FYPO:0000296","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000005":null,"FYECO:0000126":null,"FYECO:0000137":null,"FYECO:0000162":null,"FYECO:0000248":null,"FYECO:0000338":null,"FYPO:0000198":null,"FYPO:0000231":null,"FYPO:0000729":null,"FYPO:0001369":null,"FYPO:0002026":null,"FYPO:0002998":null,"FYPO:0003315":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null}}


id: PBO:0082135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin","termid":"PBO:0082135"}


id: GO:0019681
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell.","definition_xrefs":["MetaCyc:P22-PWY"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate metabolic process","termid":"GO:0006103"},{"relation_name":"is_a","term_name":"acetyl-CoA catabolic process","termid":"GO:0046356"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044248","GO:0008150","GO:0044281","GO:0006790","GO:0055086"],"is_obsolete":false,"name":"acetyl-CoA assimilation pathway","synonyms":[{"name":"acetyl-CoA catabolic process to 2-ketoglutarate","type":"exact"},{"name":"acetyl-CoA catabolic process to 2-oxoglutarate","type":"exact"},{"name":"acetyl-CoA catabolic process to alpha-ketoglutarate","type":"exact"},{"name":"acetyl-CoA catabolic process to alpha-oxoglutarate","type":"exact"},{"name":"acetyl-CoA catabolism to 2-ketoglutarate","type":"exact"},{"name":"acetyl-CoA catabolism to 2-oxoglutarate","type":"exact"},{"name":"acetyl-CoA catabolism to alpha-ketoglutarate","type":"exact"},{"name":"acetyl-CoA catabolism to alpha-oxoglutarate","type":"exact"}],"termid":"GO:0019681"}


id: GO:0009527
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle outer membrane","termid":"GO:0031968"},{"relation_name":"is_a","term_name":"plastid membrane","termid":"GO:0042170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"plastid outer membrane","termid":"GO:0009527"}


id: PBO:0034310
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_muscle_origin","termid":"PBO:0034310"}


id: PBO:0045531
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DTX2P1-UPK3BP1-PMS2P11 readthrough, transcribed pseudogene","termid":"PBO:0045531"}


id: GO:1990650
data:
  {"annotated_genes":["SJAG_00063"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[108101],"is_not":false,"summary":null,"term":"GO:1990650"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.","definition_xrefs":["GOC:al","PMID:15316017"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inositol tetrakisphosphate phosphatase activity","termid":"GO:0052743"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00063":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787","GO:0016788"],"is_obsolete":false,"name":"inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1990650","terms_by_termid":{"GO:1990650":null}}


id: FYPO:0006790
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A biological process phenotype in which meiotic drive occurs to a lower extent than normal, or does not occur at all, despite the presence of a gene or allele that normally causes drive. Meiotic drive results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to such that are unequally represented (i.e. the \\\"driver\\\" is overrepresented) among the surviving products of meiosis.","definition_xrefs":["PomBase:mah","PMID:30475921"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal biological process","termid":"FYPO:0005447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"meiotic drive suppression","synonyms":[{"name":"abolished meiotic drive","type":"related"},{"name":"decreased meiotic drive","type":"related"},{"name":"suppression of meiotic drive","type":"exact"}],"termid":"FYPO:0006790"}


id: PR:000027517
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ase1 gene or a 1:1 ortholog thereof.","definition_xrefs":["PRO:CNA"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein","termid":"PR:000000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaphase spindle elongation protein 1","pombase_gene_id":"SPAPB1A10.09","synonyms":[{"name":"Ase1p","type":"exact"},{"name":"ase1","type":"exact"}],"termid":"PR:000027517"}


id: MONDO:0007815
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete immunodeficiency with defective leukocyte and lymphocyte function and with response to histamine-1 antagonist (obsolete MONDO:0007815)","termid":"MONDO:0007815","xrefs":{"Monarch":{"xref_id":"0007815"}}}


id: MOD:00933
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Chemical derivative - 5-hydro-5-methylimidazol-4-one, arginine methylglyoxal arginine adduct (+54 amu)","definition_xrefs":["Unimod:319#R"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C3-H2-O adduct (+54 amu) of malondialdehyde with lysine or methylglyoxal with arginine.","termid":"MOD:00630"},{"relation_name":"is_a","term_name":"modified L-arginine residue","termid":"MOD:00902"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methylglyoxal arginine adduct (+54 amu)","synonyms":[{"name":"Delta:H(2)C(3)O(1)","type":"related"},{"name":"MDA adduct +54","type":"related"}],"termid":"MOD:00933"}


id: PBO:0060152
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial translation release factor in rescue","termid":"PBO:0060152"}


id: PBO:0040082
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arylsulfatase D","termid":"PBO:0040082"}


id: GO:1902730
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.","definition_xrefs":["PMID:23212449","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of glycoprotein biosynthetic process","termid":"GO:0010560"},{"relation_name":"positively_regulates","term_name":"proteoglycan biosynthetic process","termid":"GO:0030166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of proteoglycan biosynthetic process","synonyms":[{"name":"activation of proteoglycan anabolism","type":"narrow"},{"name":"activation of proteoglycan biosynthesis","type":"narrow"},{"name":"activation of proteoglycan biosynthetic process","type":"narrow"},{"name":"activation of proteoglycan formation","type":"narrow"},{"name":"activation of proteoglycan synthesis","type":"narrow"},{"name":"positive regulation of proteoglycan anabolism","type":"exact"},{"name":"positive regulation of proteoglycan biosynthesis","type":"exact"},{"name":"positive regulation of proteoglycan formation","type":"exact"},{"name":"positive regulation of proteoglycan synthesis","type":"exact"},{"name":"up regulation of proteoglycan anabolism","type":"exact"},{"name":"up regulation of proteoglycan biosynthesis","type":"exact"},{"name":"up regulation of proteoglycan biosynthetic process","type":"exact"},{"name":"up regulation of proteoglycan formation","type":"exact"},{"name":"up regulation of proteoglycan synthesis","type":"exact"},{"name":"up-regulation of proteoglycan anabolism","type":"exact"},{"name":"up-regulation of proteoglycan biosynthesis","type":"exact"},{"name":"up-regulation of proteoglycan biosynthetic process","type":"exact"},{"name":"up-regulation of proteoglycan formation","type":"exact"},{"name":"up-regulation of proteoglycan synthesis","type":"exact"},{"name":"upregulation of proteoglycan anabolism","type":"exact"},{"name":"upregulation of proteoglycan biosynthesis","type":"exact"},{"name":"upregulation of proteoglycan biosynthetic process","type":"exact"},{"name":"upregulation of proteoglycan formation","type":"exact"},{"name":"upregulation of proteoglycan synthesis","type":"exact"}],"termid":"GO:1902730"}


id: MONDO:0022560
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare disorder that affects women with a history of uterine leiomyoma, which is found to metastasise within extrauterine sites.The disease develops as a proliferation of multiple nodules composed of smooth muscle cells.The most frequent site of metastasis is the lungs, although other areas may also be affected as well, including some atypical locations, e.g. the heart or spinal cord.","definition_xrefs":["PMID:28426767"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leiomyoma","termid":"MONDO:0001572"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign metastasizing leiomyoma","secondary_identifiers":["MEDGEN:307261","UMLS:C1511090"],"termid":"MONDO:0022560","xrefs":{"Monarch":{"xref_id":"0022560"}}}


id: PR:Q10212
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein MEMO1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11060:SF0","OMA:SCHPO01586","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MEMO1 family protein C4H3.04c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4H3.04c","secondary_identifiers":["UniProtKB:Q10212"],"synonyms":[{"name":"Spom972h-MEMO1","type":"exact"}],"termid":"PR:Q10212"}


id: PBO:0034305
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-is_downstream_of_sequence_of","termid":"PBO:0034305"}


id: PBO:0029040
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_non-ionic_osmotic_stress","termid":"PBO:0029040"}


id: PBO:0012030
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"previously annotated as SPBTRNAASP.03","termid":"PBO:0012030"}


id: PBO:0052233
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium channel tetramerization domain containing 9 pseudogene 1","termid":"PBO:0052233"}


id: MONDO:0019168
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pyomyositis (PM) is a rare primary bacterial infection of the skeletal muscle, usually resulting from hematogenous spread or due to muscle injury, and characterized by pain and tenderness in the affected muscle, fever and abscess formation.","definition_xrefs":["Orphanet:764"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial myositis","termid":"MONDO:0016127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"pyomyositis","secondary_identifiers":["NCIT:C128382","GARD:4614","EFO:1001409","UMLS:C0041188","MedDRA:10037652","ICD9:040.81","DOID:876","MEDGEN:52862","MESH:D052880","icd11.foundation:856598467","SCTID:65110003"],"synonyms":[{"name":"PM","type":"exact"},{"name":"myositis purulenta tropica","type":"exact"},{"name":"myositis tropicans","type":"exact"},{"name":"suppurative myositis","type":"exact"},{"name":"tropical pyomyositis","type":"exact"}],"termid":"MONDO:0019168","xrefs":{"Monarch":{"xref_id":"0019168"}}}


id: PBO:0000189
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cdc20/Fizzy subfamily","termid":"PBO:0000189"}


id: MONDO:0016146
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of muscle diseases with basis in CAV3, which encodes caveolin-3, a muscle-specific membrane protein and the principal component of caveolae membrane in muscle cells in vivo. It is the only gene in which pathogenic variants are known to cause caveolinopathies. Sequence analysis identifies pathogenic variants in more than 99% of affected individuals","direct_ancestors":[{"relation_name":"is_a","term_name":"muscle tissue disorder","termid":"MONDO:0003939"},{"relation_name":"is_a","term_name":"qualitative or quantitative protein defects in neuromuscular diseases","termid":"MONDO:0016139"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"caveolinopathy","secondary_identifiers":["UMLS:C5679790","GARD:20394","MEDGEN:1826055","Orphanet:207078"],"synonyms":[{"name":"qualitative or quantitative defects of caveolin-3","type":"exact"}],"termid":"MONDO:0016146","xrefs":{"Monarch":{"xref_id":"0016146"}}}


id: PBO:0002823
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor Hsf1","termid":"PBO:0002823"}


id: FYPO:0005925
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein level during vegetative growth","termid":"FYPO:0000833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001312","FYPO:0001320"],"is_obsolete":false,"name":"normal protein level during mitosis","synonyms":[{"name":"normal protein accumulation during mitosis","type":"related"},{"name":"normal protein level during mitosis during vegetative growth","type":"exact"},{"name":"normal protein level during mitotic M phase","type":"related"},{"name":"normal protein level during mitotic nuclear division","type":"exact"}],"termid":"FYPO:0005925"}


id: PBO:0031109
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_microtubule-destabilizing_substance","termid":"PBO:0031109"}


id: SO:0000823
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A chromosome with origin in a leucoplast.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"has_origin","term_name":"leucoplast_sequence","termid":"SO:0000747"},{"relation_name":"is_a","term_name":"chromosome","termid":"SO:0000340"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucoplast_chromosome","synonyms":[{"name":"leucoplast chromosome","type":"exact"}],"termid":"SO:0000823"}


id: PBO:0090363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gamma tubulin complex GCP2 subunit Alp4","termid":"PBO:0090363"}


id: GO:0004686
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.","definition_xrefs":["EC:2.7.11.20","MetaCyc:2.7.11.20-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"calcium/calmodulin-dependent protein kinase activity","termid":"GO:0004683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0004672"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0140096","GO:0016301","GO:0004672","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"elongation factor-2 kinase activity","secondary_identifiers":["RHEA:21436"],"synonyms":[{"name":"ATP:elongation factor 2 phosphotransferase activity","type":"related"},{"name":"Ca/CaM-kinase III activity","type":"related"},{"name":"CaM kinase III activity","type":"related"},{"name":"EF2K","type":"related"},{"name":"STK19","type":"related"},{"name":"calmodulin-dependent protein kinase III activity","type":"related"},{"name":"eEF-2 kinase activity","type":"exact"},{"name":"eEF2 kinase activity","type":"related"},{"name":"eEF2K","type":"related"},{"name":"elongation factor 2 kinase activity","type":"related"},{"name":"eukaryotic elongation factor 2 kinase activity","type":"related"}],"termid":"GO:0004686"}


id: FYPO:0003893
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the insertion of ATP opposite an 8-oxo-7,8-dihydroguanosine (8oxodG) residue in DNA does not occur. Normally, if a guanosine residue is damaged to form 8oxodG, ATP can be misincorporated into the opposite strand to form an 8oxodG:AMP mispair that is subsequently removed.","definition_xrefs":["PomBase:mah","PMID:25106870"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal error-prone translesion synthesis","termid":"FYPO:0003892"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0000298","FYPO:0000293","FYPO:0001985"],"is_obsolete":false,"name":"abolished incorporation of ATP opposite 8-oxo-dG","synonyms":[{"name":"abolished incorporation of ATP opposite 8-oxo-7,8-dihydroguanosine","type":"exact"},{"name":"abolished insertion of ATP opposite 8-oxo-dG","type":"exact"},{"name":"incorporation of ATP opposite 8-oxo-dG abolished","type":"exact"}],"termid":"FYPO:0003893"}


id: MONDO:1011527
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hepatic lipidosis that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hepatic lipidosis, non-human animal","termid":"MONDO:1011429"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hepatic lipidosis, domestic cat","secondary_identifiers":["OMIA:000605-9685","OMIA:000548-9685"],"termid":"MONDO:1011527","xrefs":{"Monarch":{"xref_id":"1011527"}}}


id: GO:1901629
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of presynaptic membrane organization.","definition_xrefs":["PMID:22426000","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synapse organization","termid":"GO:0050807"},{"relation_name":"regulates","term_name":"presynaptic membrane organization","termid":"GO:0097090"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"regulation of presynaptic membrane organization","synonyms":[{"name":"regulation of pre-synaptic membrane organization","type":"exact"},{"name":"regulation of presynaptic membrane organisation","type":"exact"}],"termid":"GO:1901629"}


id: PBO:0004861
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.1.15","termid":"PBO:0004861"}


id: GO:0106076
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide.","definition_xrefs":["PMID:29211711"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptide N-succinyltransferase activity","termid":"GO:0106075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016746"],"is_obsolete":false,"name":"peptide-lysine-N-succinyltransferase activity","termid":"GO:0106076"}


id: MONDO:1010489
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ventricular septal defect that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ventricular septal defect, non-human animal","termid":"MONDO:1010022"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ventricular septal defect, dog","secondary_identifiers":["OMIA:001041-9615"],"termid":"MONDO:1010489","xrefs":{"Monarch":{"xref_id":"1010489"}}}


id: PBO:0087282
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Signal recognition particle (SRP) receptor alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with the beta subunit, Srp102p","termid":"PBO:0087282"}


id: PATO:0000430
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000430 unique (obsolete PATO:0000430)","termid":"PATO:0000430"}


id: GO:0050554
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.","definition_xrefs":["EC:4.2.3.18","RHEA:13873"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-oxygen lyase activity, acting on phosphates","termid":"GO:0016838"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"abietadiene synthase activity","secondary_identifiers":["MetaCyc:4.2.3.18-RXN","KEGG_REACTION:R06301"],"synonyms":[{"name":"(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)","type":"related"},{"name":"abietadiene cyclase activity","type":"related"},{"name":"copalyl-diphosphate diphosphate-lyase (cyclizing)","type":"related"}],"termid":"GO:0050554"}


id: PBO:0081244
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 14","termid":"PBO:0081244"}


id: GO:0034406
data:
  {"annotated_genes":["SJAG_00218","SJAG_01835","SJAG_01453","SJAG_03123","SJAG_03587","SJAG_01171","SJAG_02192","SJAG_04666","SJAG_00876","SJAG_00610","SJAG_04659","SJAG_02222","SJAG_04771","SJAG_01255","SJAG_04462","SJAG_01787","SJAG_05001","SJAG_03705","SJAG_04483","SJAG_01290","SJAG_05285","SJAG_04668","SJAG_03646","SJAG_01288"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94222],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034413"},{"annotations":[72696],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034412"},{"annotations":[91352,72698,75498,70462,105903,115628,74189,112968],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071970"},{"annotations":[102431,77917],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070880"},{"annotations":[101733,101732,94862,107866],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070879"},{"annotations":[92179,87264],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0140748"},{"annotations":[92163,102633,117846,90524,105715,105143,117721],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0090334"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell wall polysaccharide metabolic process","termid":"GO:0010383"},{"relation_name":"is_a","term_name":"beta-glucan metabolic process","termid":"GO:0051273"}],"gene_count":24,"genes_by_uniquename":{"SJAG_00218":null,"SJAG_00610":null,"SJAG_00876":null,"SJAG_01171":null,"SJAG_01255":null,"SJAG_01288":null,"SJAG_01290":null,"SJAG_01453":null,"SJAG_01787":null,"SJAG_01835":null,"SJAG_02192":null,"SJAG_02222":null,"SJAG_03123":null,"SJAG_03587":null,"SJAG_03646":null,"SJAG_03705":null,"SJAG_04462":null,"SJAG_04483":null,"SJAG_04659":null,"SJAG_04666":null,"SJAG_04668":null,"SJAG_04771":null,"SJAG_05001":null,"SJAG_05285":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0071554"}],"interesting_parent_ids":["GO:0071554","GO:0008150","GO:0005975"],"is_obsolete":false,"name":"cell wall beta-glucan metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"cell wall beta-glucan metabolism","type":"exact"}],"termid":"GO:0034406","terms_by_termid":{"GO:0034412":null,"GO:0034413":null,"GO:0070879":null,"GO:0070880":null,"GO:0071970":null,"GO:0090334":null,"GO:0140748":null}}


id: GO:1900131
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.","definition_xrefs":["GOC:pm","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of binding","termid":"GO:0051100"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of lipid binding","synonyms":[{"name":"down regulation of lipid binding","type":"exact"},{"name":"down-regulation of lipid binding","type":"exact"},{"name":"downregulation of lipid binding","type":"exact"},{"name":"inhibition of lipid binding","type":"narrow"}],"termid":"GO:1900131"}


id: PBO:0055280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2707","termid":"PBO:0055280"}


id: PBO:0026947
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_transcription_during_meiotic_cell_cycle","termid":"PBO:0026947"}


id: PBO:0067142
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 190, pseudogene","termid":"PBO:0067142"}


id: PBO:0040673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"B cell receptor associated protein 31 pseudogene 1","termid":"PBO:0040673"}


id: PBO:0052921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin associated protein 19-4","termid":"PBO:0052921"}


id: MONDO:0700234
data:
  {"annotated_genes":["SJAG_04497"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85969],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010806"}]},"cv_name":"mondo","definition":"Any retinopathy caused by a variant in the PRPF8 gene.","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited retinal dystrophy","termid":"MONDO:0019118"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04497":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"PRPF8-related retinopathy","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"PRPF8-related retinopathy","type":"exact"}],"termid":"MONDO:0700234","terms_by_termid":{"MONDO:0010806":null},"xrefs":{"Monarch":{"xref_id":"0700234"}}}


id: PBO:0053990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1309","termid":"PBO:0053990"}


id: PR:O59740
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mod5 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O59740"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell polarity protein mod5 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC530.04","synonyms":[{"name":"Spom972h-mod5","type":"exact"},{"name":"tea1-anchoring protein mod5 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O59740"}


id: PBO:0089905
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytoskeletal signaling protein Slm1","termid":"PBO:0089905"}


id: PBO:0087426
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit a of the vacuolar-ATPase V0 domain; encodes one of two isoforms, located in vacuolar V-ATPase complexes while STV1 encodes the second isoform and is located in Golgi and endosomal V-ATPase complexes; interaction with PI(3,5)P2 increases V-ATPase activity and contributes to hyperosmotic stress tolerance; relative distribution to the vacuolar membrane decreases upon DNA replication stress; human homolog ATP6V0A4 implicated in renal tubular acidosis, can complement yeast null mutant","termid":"PBO:0087426"}


id: GO:2000085
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis","termid":"GO:2000084"},{"relation_name":"is_a","term_name":"negative regulation of epithelial cell differentiation involved in kidney development","termid":"GO:2000697"},{"relation_name":"negatively_regulates","term_name":"mesenchymal to epithelial transition involved in mesonephros morphogenesis","termid":"GO:0061261"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis","synonyms":[{"name":"negative regulation of mesonephric mesenchyme to epithelial transition","type":"related"}],"termid":"GO:2000085"}


id: PBO:0044247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cut like homeobox 2 pseudogene 2","termid":"PBO:0044247"}


id: MONDO:0013209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD) is a type of liver disease that is not caused by alcohol. It typically does not cause symptoms in the early stages, but it can cause health problems due to fat accumulation, inflammation, and scarring in the liver.","direct_ancestors":[{"relation_name":"is_a","term_name":"fatty liver disease","termid":"MONDO:0004790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004335"],"is_obsolete":false,"name":"metabolic dysfunction-associated steatotic liver disease","secondary_identifiers":["MedDRA:10029530","DOID:0080546","EFO:0003095","ICD9:571.8","Orphanet:33271","NCIT:C84444","DOID:0080208","MESH:D065626","SCTID:197315008","MEDGEN:96033","UMLS:C0400966"],"synonyms":[{"name":"MASLD","type":"exact"},{"name":"NAFLD","type":"exact"},{"name":"NAFLD - nonalcoholic fatty liver disease","type":"exact"},{"name":"NAFLD1","type":"related"},{"name":"fatty liver disease, nonalcoholic","type":"exact"},{"name":"fatty liver disease, nonalcoholic, susceptibility to, 1","type":"related"},{"name":"liver disease, alcoholic, susceptibility to, 1","type":"related"},{"name":"non-alcoholic fatty liver","type":"exact"},{"name":"non-alcoholic fatty liver disease","type":"exact"},{"name":"nonalcoholic fatty liver disease","type":"exact"}],"termid":"MONDO:0013209","xrefs":{"Monarch":{"xref_id":"0013209"}}}


