# terms

id: PBO:0053531
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 529","termid":"PBO:0053531"}


id: PBO:0067498
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 634, pseudogene","termid":"PBO:0067498"}


id: FYPO:0006456
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the meiotic spindle is abolished during the second meiotic nuclear division.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to microtubule cytoskeleton","termid":"FYPO:0004091"},{"relation_name":"is_a","term_name":"abolished protein localization during meiotic cell cycle","termid":"FYPO:0005208"},{"relation_name":"is_a","term_name":"abnormal protein localization to meiotic spindle","termid":"FYPO:0006454"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0000138","FYPO:0005447"],"is_obsolete":false,"name":"abolished protein localization to meiotic spindle during meiosis II","synonyms":[{"name":"abolished protein localisation to meiotic spindle during meiosis II","type":"exact"},{"name":"abolished protein localization to meiosis II spindle","type":"exact"},{"name":"abolished protein localization to meiotic spindle pole body during second meiotic nuclear division","type":"exact"},{"name":"abolished protein localization to spindle during meiosis II","type":"exact"},{"name":"protein localization to meiotic spindle abolished during meiosis II","type":"exact"}],"termid":"FYPO:0006456"}


id: PBO:0081845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNF778 divergent transcript","termid":"PBO:0081845"}


id: MONDO:0007687
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"graying of hair, precocious","secondary_identifiers":["MESH:C564209","MEDGEN:374795","OMIM:139100","UMLS:C1841809"],"synonyms":[{"name":"White hair, premature","type":"related"},{"name":"graying of hair, precocious","type":"exact"}],"termid":"MONDO:0007687","xrefs":{"Monarch":{"xref_id":"0007687"}}}


id: PBO:0063868
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol glycan anchor biosynthesis class A pseudogene 1","termid":"PBO:0063868"}


id: PBO:0005876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Methionine, mitochondrial","termid":"PBO:0005876"}


id: GO:1903542
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.","definition_xrefs":["PMID:24105262","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of exocytosis","termid":"GO:0045920"},{"relation_name":"is_a","term_name":"regulation of exosomal secretion","termid":"GO:1903541"},{"relation_name":"negatively_regulates","term_name":"exosomal secretion","termid":"GO:1990182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0016192","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of exosomal secretion","synonyms":[{"name":"down regulation of exosomal protein secretion","type":"narrow"},{"name":"down regulation of exosomal secretion","type":"exact"},{"name":"down regulation of exosomal secretory pathway","type":"exact"},{"name":"down regulation of extracellular vesicular exosome secretion","type":"exact"},{"name":"down regulation of secretion of exosome","type":"exact"},{"name":"down-regulation of exosomal protein secretion","type":"narrow"},{"name":"down-regulation of exosomal secretion","type":"exact"},{"name":"down-regulation of exosomal secretory pathway","type":"exact"},{"name":"down-regulation of extracellular vesicular exosome secretion","type":"exact"},{"name":"down-regulation of secretion of exosome","type":"exact"},{"name":"downregulation of exosomal protein secretion","type":"narrow"},{"name":"downregulation of exosomal secretion","type":"exact"},{"name":"downregulation of exosomal secretory pathway","type":"exact"},{"name":"downregulation of extracellular vesicular exosome secretion","type":"exact"},{"name":"downregulation of secretion of exosome","type":"exact"},{"name":"inhibition of exosomal protein secretion","type":"narrow"},{"name":"inhibition of exosomal secretion","type":"narrow"},{"name":"inhibition of exosomal secretory pathway","type":"narrow"},{"name":"inhibition of extracellular vesicular exosome secretion","type":"narrow"},{"name":"inhibition of secretion of exosome","type":"narrow"},{"name":"negative regulation of exosomal protein secretion","type":"narrow"},{"name":"negative regulation of exosomal secretory pathway","type":"exact"},{"name":"negative regulation of extracellular vesicular exosome secretion","type":"exact"},{"name":"negative regulation of secretion of exosome","type":"exact"}],"termid":"GO:1903542"}


id: GO:0047235
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.","definition_xrefs":["MetaCyc:2.4.1.167-RXN","EC:2.4.1.167"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-galactosyltransferase activity","termid":"GO:0035250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016757","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"sucrose 6F-alpha-galactotransferase activity","secondary_identifiers":["RHEA:10088"],"synonyms":[{"name":"UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity","type":"related"},{"name":"UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity","type":"related"},{"name":"UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity","type":"related"},{"name":"sucrose 6(F)-alpha-galactosyltransferase activity","type":"exact"},{"name":"sucrose 6F-alpha-galactosyltransferase activity","type":"related"},{"name":"uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity","type":"related"}],"termid":"GO:0047235"}


id: MOD:00680
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively adds oxygen atoms to a sulfur atom of a residue without removing hydrogen atoms.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxygenated residue","termid":"MOD:00676"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulfur oxygenated residue","synonyms":[{"name":"SOxyRes","type":"exact"}],"termid":"MOD:00680"}


id: PBO:0090860
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell surface adhesion protein for conjugation","termid":"PBO:0090860"}


id: PBO:0082231
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching","termid":"PBO:0082231"}


id: GO:0003673
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A controlled vocabulary that can be applied to all organisms even as knowledge of gene and protein roles in cells is accumulating and changing. GO provides three structured networks of defined terms to describe gene product attributes.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete Gene_Ontology (obsolete GO:0003673)","synonyms":[{"name":"Gene_Ontology","type":"exact"}],"termid":"GO:0003673"}


id: PBO:0087212
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S-adenosylmethionine-dependent protein methyltransferase; capable of automethylation; member of the seven beta-strand family; YNL092W is not an essential gene","termid":"PBO:0087212"}


id: PBO:0014257
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Small Tyrosine Phosphatase","termid":"PBO:0014257"}


id: PBO:0084662
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial 3-hydroxyacyl-thioester dehydratase; involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology","termid":"PBO:0084662"}


id: PBO:0003238
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spindle pole body protein Cut12","termid":"PBO:0003238"}


id: GO:1905587
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process.","definition_xrefs":["GOC:TermGenie","PMID:24472721","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of neuron apoptotic process","termid":"GO:0043525"},{"relation_name":"is_a","term_name":"regulation of outer hair cell apoptotic process","termid":"GO:1905585"},{"relation_name":"positively_regulates","term_name":"outer hair cell apoptotic process","termid":"GO:1905584"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of outer hair cell apoptotic process","synonyms":[{"name":"activation of cochlear outer hair cell apoptosis","type":"narrow"},{"name":"activation of cochlear outer hair cell apoptotic process","type":"narrow"},{"name":"activation of outer hair cell apoptosis","type":"narrow"},{"name":"activation of outer hair cell apoptotic process","type":"narrow"},{"name":"positive regulation of cochlear outer hair cell apoptosis","type":"narrow"},{"name":"positive regulation of cochlear outer hair cell apoptotic process","type":"exact"},{"name":"positive regulation of outer hair cell apoptosis","type":"narrow"},{"name":"up regulation of cochlear outer hair cell apoptosis","type":"narrow"},{"name":"up regulation of cochlear outer hair cell apoptotic process","type":"exact"},{"name":"up regulation of outer hair cell apoptosis","type":"narrow"},{"name":"up regulation of outer hair cell apoptotic process","type":"exact"},{"name":"up-regulation of cochlear outer hair cell apoptosis","type":"narrow"},{"name":"up-regulation of cochlear outer hair cell apoptotic process","type":"exact"},{"name":"up-regulation of outer hair cell apoptosis","type":"narrow"},{"name":"up-regulation of outer hair cell apoptotic process","type":"exact"},{"name":"upregulation of cochlear outer hair cell apoptosis","type":"narrow"},{"name":"upregulation of cochlear outer hair cell apoptotic process","type":"exact"},{"name":"upregulation of outer hair cell apoptosis","type":"narrow"},{"name":"upregulation of outer hair cell apoptotic process","type":"exact"}],"termid":"GO:1905587"}


id: PBO:0057949
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3671","termid":"PBO:0057949"}


id: PBO:0029573
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_after_spore_germination,_multiple_cell_divisions,_abnormal_morphology","termid":"PBO:0029573"}


id: MONDO:1010720
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any deficiency in fumarylacetoacetate hydrolase that occurs in pigs due to a mutation in the FAH gene created by genetic engineering or gene editing. Fumarylacetoacetate hydrolase is an enzyme that catalyzes the last step of tyrosine metabolism.","definition_xrefs":["OMIA:002078-9823"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"metabolic disease, non-human animal","termid":"MONDO:1011331"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tyrosinemia type 1, FAH-related, pig","synonyms":[{"name":"tyrosinemia type I, pig","type":"related"}],"termid":"MONDO:1010720","xrefs":{"Monarch":{"xref_id":"1010720"}}}


id: GO:0032428
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.","definition_xrefs":["EC:3.2.1.53"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-N-acetylhexosaminidase activity","termid":"GO:0004563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016798"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824","GO:0016798"],"is_obsolete":false,"name":"beta-N-acetylgalactosaminidase activity","secondary_identifiers":["MetaCyc:3.2.1.53-RXN"],"termid":"GO:0032428"}


id: PATO:0001940
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A size quality inhering in a bearer by virtue of the bearer's being many folds greater relative to the normal average.","definition_xrefs":["PATOC:UMH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased size","termid":"PATO:0000586"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gigantic","synonyms":[{"name":"giant","type":"exact"}],"termid":"PATO:0001940"}


id: GO:0034624
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete DNA recombinase assembly involved in gene conversion at mating-type locus (obsolete GO:0034624)","termid":"GO:0034624"}


id: FYPO:0007022
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 2'-O-methylguanosine does not occur.","definition_xrefs":["PMID:25404562","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal tRNA methylation","termid":"FYPO:0001766"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000294","FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000002","FYPO:0006551"],"is_obsolete":false,"name":"abolished tRNA guanosine 2'-O-methylation","synonyms":[{"name":"2'-O-methylguanosine absent from tRNA","type":"related"},{"name":"abolished tRNA 2'-O-methylguanosine formation","type":"exact"},{"name":"abolished tRNA Gm formation","type":"exact"},{"name":"abolished tRNA guanosine 2'-O-methylation during mitotic cell cycle","type":"related"},{"name":"abolished tRNA guanosine 2'-O-methylation during vegetative growth","type":"exact"},{"name":"tRNA guanosine 2'-O-methylation abolished","type":"exact"}],"termid":"FYPO:0007022"}


id: GO:0051165
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving 2,5-dihydroxypyridine.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyridine-containing compound metabolic process","termid":"GO:0072524"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"2,5-dihydroxypyridine metabolic process","synonyms":[{"name":"2,5-dihydroxypyridine metabolism","type":"exact"},{"name":"pyridine-2,5-diol metabolic process","type":"exact"}],"termid":"GO:0051165"}


id: PBO:0050100
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 10","termid":"PBO:0050100"}


id: GO:0102355
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H+.","definition_xrefs":["GOC:pz","EC:3.1.1.91"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016788","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity","secondary_identifiers":["MetaCyc:RXN-13371","RHEA:33967"],"termid":"GO:0102355"}


id: MONDO:0030866
data:
  {"annotated_genes":["SJAG_03914","SJAG_01766"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85665,85666],"is_not":false,"summary":null,"term":"MONDO:0030866"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01766":null,"SJAG_03914":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1750805","UMLS:C5436848","OMIM:619121","DOID:0070543"],"synonyms":[{"name":"NEDCASB","type":"exact"}],"termid":"MONDO:0030866","terms_by_termid":{"MONDO:0030866":null},"xrefs":{"Monarch":{"xref_id":"0030866"}}}


id: GO:0043155
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of photosynthesis, light reaction","termid":"GO:0042548"},{"relation_name":"is_a","term_name":"negative regulation of photosynthesis","termid":"GO:1905156"},{"relation_name":"negatively_regulates","term_name":"photosynthesis, light reaction","termid":"GO:0019684"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006091"}],"interesting_parent_ids":["GO:0006091","GO:0008150"],"is_obsolete":false,"name":"negative regulation of photosynthesis, light reaction","synonyms":[{"name":"down regulation of photosynthesis, light reaction","type":"exact"},{"name":"down-regulation of photosynthesis, light reaction","type":"exact"},{"name":"downregulation of photosynthesis, light reaction","type":"exact"},{"name":"inhibition of photosynthesis, light reaction","type":"narrow"}],"termid":"GO:0043155"}


id: PR:P78875
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- tpp1 gene.","definition_xrefs":["UniProtKB:P78875","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trehalose-phosphatase tpp1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC19G12.15c","synonyms":[{"name":"SPAC19G12.15c","type":"related"},{"name":"Spom972h-tpp1","type":"exact"},{"name":"TPP tpp1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"trehalose-6-phosphate phosphatase tpp1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P78875"}


id: PBO:0071094
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 96","termid":"PBO:0071094"}


id: RO:0002110
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. ","direct_ancestors":[{"relation_name":"is_a","term_name":"has_synaptic_terminal_in","termid":"RO:0002130"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_postsynaptic_terminal_in","termid":"RO:0002110"}


id: PBO:0045234
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DnaJ heat shock protein family (Hsp40) member C19 pseudogene 2","termid":"PBO:0045234"}


id: PBO:0088986
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fructose-bisphosphate aldolase, class-II","termid":"PBO:0088986"}


id: MONDO:0100060
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital/infantile spindle cell rhabdomyosarcoma characterized by the presence of gene fusions involving the VGLL2, SRF, TEAD1, NCOA2, and CITED2 genes.","definition_xrefs":["NCIT:C178232"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spindle cell rhabdomyosarcoma","termid":"MONDO:0002581"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"congenital/infantile spindle cell rhabdomyosarcoma with VGLL2/NCOA2/CITED2 rearrangements","secondary_identifiers":["MEDGEN:1791325","UMLS:C5554884"],"termid":"MONDO:0100060","xrefs":{"Monarch":{"xref_id":"0100060"}}}


id: GO:0051052
data:
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id: GO:0048792
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id: PR:000050476
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  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein kinase wis1 (Schizosaccharomyces pombe) that has not been phosphorylated on residues equivalent to Ser-469 and Thr-473 of the amino acid sequence represented by UniProtKB:P33886. Example: UniProtKB:P33886, Ser-469/Thr-473, PR:000026291.","definition_xrefs":["PomBase:VW","PMID:12181336","PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein kinase wis1 (Schizosaccharomyces pombe)","termid":"PR:000050474"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wis1/UnPhos:(S469,T473)","pombase_gene_id":"SPBC409.07c","synonyms":[{"name":"PomBase_original_PRO_term_name: protein kinase wis1 unphosphorylated 1 (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-wis1/UnPhos:1","type":"exact"},{"name":"UniProtKB:P33886, Ser-469/Thr-473, PR:000026291","type":"narrow"},{"name":"wis1/UnPhos:(S469,T473)","type":"exact"}],"termid":"PR:000050476"}


id: PBO:0044522
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id: GO:0034145
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id: PBO:0108967
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CIMAP1 family member D","termid":"PBO:0108967"}


id: PBO:0071605
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L36a pseudogene 23","termid":"PBO:0071605"}


id: PBO:0117152
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WDR4 tRNA N7-guanosine methyltransferase non-catalytic subunit","termid":"PBO:0117152"}


id: PBO:0049477
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H1.1 linker histone, cluster member","termid":"PBO:0049477"}


id: PR:O94276
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  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- stc1 gene.","definition_xrefs":["UniProtKB:O94276","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic chromosome segregation protein P8B7.28c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBP8B7.28c","synonyms":[{"name":"Spom972h-stc1","type":"exact"}],"termid":"PR:O94276"}


id: GO:0031773
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a kisspeptin receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuropeptide receptor binding","termid":"GO:0071855"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"kisspeptin receptor binding","synonyms":[{"name":"G-protein coupled receptor 54 binding","type":"exact"},{"name":"KiSS-1 receptor binding","type":"exact"},{"name":"hOT7T175 receptor binding","type":"exact"},{"name":"hypogonadotropin-1 receptor binding","type":"exact"},{"name":"kisspeptin receptor ligand","type":"narrow"},{"name":"metastin receptor binding","type":"exact"}],"termid":"GO:0031773"}


id: MONDO:0005646
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete anisakiasis (obsolete MONDO:0005646)","termid":"MONDO:0005646","xrefs":{"Monarch":{"xref_id":"0005646"}}}


id: GO:0033310
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways leading to the breakdown of chlorophyll a.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chlorophyll catabolic process","termid":"GO:0015996"},{"relation_name":"is_a","term_name":"chlorophyll a metabolic process","termid":"GO:0033304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0033013"}],"interesting_parent_ids":["GO:0033013","GO:0008150"],"is_obsolete":false,"name":"chlorophyll a catabolic process","secondary_identifiers":["MetaCyc:PWY-5098"],"synonyms":[{"name":"chlorophyll a breakdown","type":"exact"},{"name":"chlorophyll a catabolism","type":"exact"},{"name":"chlorophyll a degradation","type":"exact"}],"termid":"GO:0033310"}


id: MONDO:0033571
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  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete skeletal muscle glycogen content and metabolism quantitative trait locus (obsolete MONDO:0033571)","secondary_identifiers":["OMIM:619030"],"synonyms":[{"name":"SKELETAL MUSCLE GLYCOGEN CONTENT AND METABOLISM QUANTITATIVE TRAIT LOCUS","type":"related"},{"name":"SMGMQTL","type":"related"},{"name":"Skeletal muscle glycogen content and metabolism QTL","type":"exact"}],"termid":"MONDO:0033571","xrefs":{"Monarch":{"xref_id":"0033571"}}}


id: PBO:0038275
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase allele types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amino_acid_insertion_and_mutation","termid":"PBO:0038275"}


id: PBO:0088587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Prp19 complex WD repeat protein Prp17","termid":"PBO:0088587"}


id: PBO:0070540
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7a pseudogene 6","termid":"PBO:0070540"}


id: PBO:0005038
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fun thirty related protein Fft2 (predicted)","termid":"PBO:0005038"}


id: GO:0035948
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.","definition_xrefs":["PMID:17875938","GOC:dgf"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter (obsolete GO:0035948)","synonyms":[{"name":"regulation of gluconeogenesis by activation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of gluconeogenesis by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"regulation of gluconeogenesis by stimulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of gluconeogenesis by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of gluconeogenesis by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of gluconeogenesis by upregulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of glucose biosynthesis by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"regulation of glucose biosynthesis by positive regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of glucose biosynthesis by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of glucose biosynthesis by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of glucose biosynthesis by upregulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of glucose biosynthetic process by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"regulation of glucose biosynthetic process by positive regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"regulation of glucose biosynthetic process by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of glucose biosynthetic process by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"regulation of glucose biosynthetic process by upregulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:0035948"}


id: PBO:0050037
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"major histocompatibility complex, class II, DR beta 5","termid":"PBO:0050037"}


id: GO:0036259
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen.","definition_xrefs":["PMID:10082789","GOC:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"raffinose catabolic process","termid":"GO:0034484"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"aerobic raffinose catabolic process","synonyms":[{"name":"aerobic raffinose breakdown","type":"exact"},{"name":"aerobic raffinose catabolism","type":"exact"},{"name":"aerobic raffinose degradation","type":"exact"}],"termid":"GO:0036259"}


id: PBO:0014607
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein phosphatase, PP4 complex subunit Pph3 (predicted)","termid":"PBO:0014607"}


id: MONDO:0005506
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An cancer with eccrine differentiation arising from the sweat glands.B","definition_xrefs":["EFO:0005553"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eccrine sweat gland neoplasm","termid":"MONDO:0002090"},{"relation_name":"is_a","term_name":"sweat gland cancer","termid":"MONDO:0002206"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005093"],"is_obsolete":false,"name":"eccrine sweat gland cancer","secondary_identifiers":["DOID:4921","NCIT:C5559","UMLS:C1334577","MEDGEN:233660"],"synonyms":[{"name":"cancer of eccrine sweat gland","type":"exact"},{"name":"eccrine sweat gland cancer","type":"exact"},{"name":"malignant eccrine neoplasm","type":"exact"},{"name":"malignant eccrine neoplasm of skin","type":"exact"},{"name":"malignant eccrine neoplasm of the skin","type":"exact"},{"name":"malignant eccrine skin neoplasm","type":"exact"},{"name":"malignant eccrine skin tumor","type":"exact"},{"name":"malignant eccrine skin tumour","type":"exact"},{"name":"malignant eccrine sweat gland neoplasm","type":"exact"},{"name":"malignant eccrine tumor","type":"exact"},{"name":"malignant eccrine tumor of skin","type":"exact"},{"name":"malignant eccrine tumor of the skin","type":"exact"},{"name":"malignant eccrine tumour","type":"exact"},{"name":"malignant eccrine tumour of skin","type":"exact"},{"name":"malignant eccrine tumour of the skin","type":"exact"},{"name":"malignant neoplasm of eccrine sweat gland","type":"exact"}],"termid":"MONDO:0005506","xrefs":{"Monarch":{"xref_id":"0005506"}}}


id: MONDO:0003699
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An anxiety disorder characterized by an intense, irrational fear of an object, activity, or situation. The individual seeks to avoid the object, activity, or situation. In adults, the individual recognizes that the fear is excessive or unreasonable.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anxiety disorder","termid":"MONDO:0005618"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phobic disorder","secondary_identifiers":["ICD9:300.2","DOID:591","MESH:D010698","MEDGEN:83881","UMLS:C0349231","EFO:1001908","ICD9:300.20","NCIT:C35420","SCTID:386810004"],"synonyms":[{"name":"phobia","type":"exact"}],"termid":"MONDO:0003699","xrefs":{"Monarch":{"xref_id":"0003699"}}}


id: PBO:0051072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy diversity 5-24 (non-functional)","termid":"PBO:0051072"}


id: PR:Q9P6I0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An asparagine--tRNA ligase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02355","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"asparagine--tRNA ligase, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1198.10c","secondary_identifiers":["UniProtKB:Q9P6I0"],"synonyms":[{"name":"AsnRS (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-NARS2","type":"exact"},{"name":"asparaginyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P6I0"}


id: PBO:0025448
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-Acetylglutamate Synthetase deficiency","termid":"PBO:0025448"}


id: PBO:0041854
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"caspase 2","termid":"PBO:0041854"}


id: GO:1900351
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of biosynthetic process","termid":"GO:0009889"},{"relation_name":"is_a","term_name":"regulation of pteridine metabolic process","termid":"GO:0042068"},{"relation_name":"is_a","term_name":"regulation of methanofuran metabolic process","termid":"GO:1900354"},{"relation_name":"regulates","term_name":"methanofuran biosynthetic process","termid":"GO:2001120"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of methanofuran biosynthetic process","synonyms":[{"name":"regulation of methanofuran biosynthesis","type":"exact"}],"termid":"GO:1900351"}


id: PBO:0068987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 231, pseudogene","termid":"PBO:0068987"}


id: MONDO:0030934
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"intellectual disability, autosomal dominant","termid":"MONDO:0100172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"intellectual developmental disorder, autosomal dominant 64","secondary_identifiers":["MEDGEN:1784554","GARD:16478","OMIM:619188","UMLS:C5543067"],"synonyms":[{"name":"MRD64","type":"exact"},{"name":"intellectual developmental disorder, autosomal dominant 64","type":"exact"},{"name":"mental retardation, autosomal dominant 64","type":"exact"}],"termid":"MONDO:0030934","xrefs":{"Monarch":{"xref_id":"0030934"}}}


id: GO:0052194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of an organism or motile cell on or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete movement on or near symbiont (obsolete GO:0052194)","termid":"GO:0052194"}


id: FYPO:0004973
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which telomere localization, a process in which a telomere is transported to, and/or maintained in, a specific location, is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process","termid":"FYPO:0000627"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal telomere localization","synonyms":[{"name":"normal telomere localisation","type":"exact"}],"termid":"FYPO:0004973"}


id: PBO:0083627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones; interacts with Dia2p and is required for Dia2p degradation; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase","termid":"PBO:0083627"}


id: PR:O13622
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mss116 gene.","definition_xrefs":["UniProtKB:O13622","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase mss116, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC691.04","synonyms":[{"name":"Spom972h-mss116","type":"exact"}],"termid":"PR:O13622"}


id: PBO:0062388
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily E member 8 pseudogene","termid":"PBO:0062388"}


id: PBO:0012568
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae SEC4","termid":"PBO:0012568"}


id: GO:0035561
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.","definition_xrefs":["GOC:bf","PMID:20404130"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of chromatin binding (obsolete GO:0035561)","termid":"GO:0035561"}


id: MONDO:0006910
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pituitary-dependent Cushing disease (obsolete MONDO:0006910)","termid":"MONDO:0006910","xrefs":{"Monarch":{"xref_id":"0006910"}}}


id: PATO:0000977
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000977 absolute permeability value (obsolete PATO:0000977)","termid":"PATO:0000977"}


id: PBO:0052561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysine methyltransferase 2A","termid":"PBO:0052561"}


id: MONDO:0011661
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inflammatory bowel disease that has material basis in variation in the chromosome region 5q31.","definition_xrefs":["PMID:11586304","DOID:0110889"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inflammatory bowel disease","termid":"MONDO:0005265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004335"],"is_obsolete":false,"name":"inflammatory bowel disease 5","secondary_identifiers":["MEDGEN:342879","UMLS:C1853438","MESH:C565234","OMIM:606348"],"synonyms":[{"name":"IBD5","type":"exact"},{"name":"inflammatory bowel disease 5","type":"exact"},{"name":"inflammatory bowel disease type 5","type":"exact"}],"termid":"MONDO:0011661","xrefs":{"Monarch":{"xref_id":"0011661"}}}


id: PBO:0070620
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7 like 1 pseudogene 4","termid":"PBO:0070620"}


id: GO:0031809
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a H3 histamine receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled histamine receptor binding","termid":"GO:0031806"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"H3 histamine receptor binding","synonyms":[{"name":"H3 histamine receptor ligand","type":"narrow"}],"termid":"GO:0031809"}


id: MOD:00464
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-tryptophan residue to N'-formyl-L-kynurenine.","definition_xrefs":["DeltaMass:356","OMSSA:45","PubMed:12124932","PubMed:12686488","PubMed:9252331","Unimod:425#W"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon oxygenated residue","termid":"MOD:00679"},{"relation_name":"is_a","term_name":"modified L-tryptophan residue","termid":"MOD:00918"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N'-formyl-L-kynurenine","synonyms":[{"name":"Dioxidation","type":"related"},{"name":"Double oxidation of Trp","type":"exact"},{"name":"dihydroxy","type":"related"},{"name":"formylkynureninw","type":"exact"},{"name":"tryptophan oxidation to formylkynurenin","type":"related"}],"termid":"MOD:00464"}


id: MONDO:0005893
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is more than 20 per 10 HPF. According to the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm, it is classified either as small or large cell neuroendocrine carcinoma.","definition_xrefs":["NCIT:C3770"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuroendocrine carcinoma","termid":"MONDO:0002120"},{"relation_name":"is_a","term_name":"pancreatic neuroendocrine neoplasm","termid":"MONDO:0005815"},{"relation_name":"is_a","term_name":"digestive system carcinoma","termid":"MONDO:0006181"},{"relation_name":"is_a","term_name":"malignant pancreatic neoplasm","termid":"MONDO:0009831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"pancreatic endocrine carcinoma","secondary_identifiers":["UMLS:C1328479","SCTID:254612002","ICD10CM:C25.4","MESH:D018273","MEDGEN:233070","EFO:0007416","Orphanet:506098","DOID:1798","ICDO:8150/3","GARD:22056","ICD9:157.4"],"synonyms":[{"name":"Pancreatic Neuroendocrine cancer","type":"exact"},{"name":"carcinoma of endocrine pancreas","type":"exact"},{"name":"carcinoma, islet cell, malignant","type":"exact"},{"name":"endocrine pancreas carcinoma","type":"exact"},{"name":"high grade pancreatic neuroendocrine carcinoma","type":"exact"},{"name":"high-grade pancreatic neuroendocrine carcinoma","type":"exact"},{"name":"islet cell cancer","type":"exact"},{"name":"islet cell carcinoma","type":"exact"},{"name":"islet cell carcinoma (morphologic abnormality)","type":"exact"},{"name":"malignant islet cell tumor","type":"exact"},{"name":"malignant islet cell tumour","type":"exact"},{"name":"malignant neoplasm of islets of Langerhans","type":"exact"},{"name":"malignant pancreatic endocrine tumor","type":"exact"},{"name":"malignant pancreatic endocrine tumour","type":"exact"},{"name":"neuroendocrine carcinoma of pancreas","type":"related"},{"name":"pancreatic NEC","type":"exact"},{"name":"pancreatic NEC G3","type":"exact"},{"name":"pancreatic endocrine cancer","type":"exact"},{"name":"pancreatic endocrine carcinoma","type":"exact"},{"name":"pancreatic neuroendocrine carcinoma","type":"exact"},{"name":"poorly differentiated pancreatic endocrine carcinoma","type":"exact"},{"name":"poorly-differentiated NEN of pancreas","type":"exact"},{"name":"poorly-differentiated neuroendocrine neoplasm of pancreas","type":"exact"},{"name":"poorly-differentiated pancreatic NEN","type":"exact"},{"name":"poorly-differentiated pancreatic neuroendocrine neoplasm","type":"exact"}],"termid":"MONDO:0005893","xrefs":{"Monarch":{"xref_id":"0005893"}}}


id: MONDO:0012218
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dandy-walker malformation with occipital cephalocele, autosomal dominant","secondary_identifiers":["OMIM:609222","MEDGEN:393273","UMLS:C2674987","MESH:C567185"],"synonyms":[{"name":"ADDWOC","type":"exact"},{"name":"Dandy-Walker malformation with occipital cephalocele, autosomal dominant","type":"related"}],"termid":"MONDO:0012218","xrefs":{"Monarch":{"xref_id":"0012218"}}}


id: PBO:0074776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 3I","termid":"PBO:0074776"}


id: PBO:0076544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tyrosine aminotransferase","termid":"PBO:0076544"}


id: PBO:0040734
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCR activator of RhoGEF and GTPase","termid":"PBO:0040734"}


id: MONDO:0001462
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the descending colon.","direct_ancestors":[{"relation_name":"is_a","term_name":"malignant colon neoplasm","termid":"MONDO:0021063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"descending colon cancer","secondary_identifiers":["MEDGEN:509291","UMLS:C0153435","ICD9:153.2","DOID:12190","SCTID:363409003"],"synonyms":[{"name":"Ca descending colon","type":"exact"},{"name":"cancer of descending colon","type":"exact"},{"name":"descending colon cancer","type":"exact"},{"name":"malignant descending colon neoplasm","type":"exact"},{"name":"malignant neoplasm of descending colon","type":"exact"},{"name":"malignant neoplasm of left colon","type":"exact"},{"name":"malignant tumor of descending colon","type":"exact"},{"name":"malignant tumour of descending colon","type":"exact"}],"termid":"MONDO:0001462","xrefs":{"Monarch":{"xref_id":"0001462"}}}


id: PR:Q9P3T9
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- bsd1 gene.","definition_xrefs":["UniProtKB:Q9P3T9","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metal homeostasis protein bsd1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC328.07c","synonyms":[{"name":"Spom972h-bsd1","type":"exact"}],"termid":"PR:Q9P3T9"}


id: PBO:0067843
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 145","termid":"PBO:0067843"}


id: GO:1990061
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.","definition_xrefs":["GOC:bhm","PMID:21805185"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic exosome (RNase complex)","termid":"GO:0000177"},{"relation_name":"part_of","term_name":"cytosol","termid":"GO:0005829"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005829"}],"interesting_parent_ids":["GO:0005829","GO:0005575","GO:0005737","GO:0032991"],"is_obsolete":false,"name":"bacterial degradosome","termid":"GO:1990061"}


id: FYPO:0005042
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to centromere","termid":"FYPO:0007853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal protein localization to kinetochore","synonyms":[{"name":"normal protein localisation to kinetochore","type":"exact"}],"termid":"FYPO:0005042"}


id: GO:0080173
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana.","definition_xrefs":["PMID:21123745"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell recognition","termid":"GO:0009988"},{"relation_name":"is_a","term_name":"cellular process involved in reproduction in multicellular organism","termid":"GO:0022412"},{"relation_name":"part_of","term_name":"fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm","termid":"GO:0061936"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0061024"],"is_obsolete":false,"name":"male-female gamete recognition during double fertilization forming a zygote and endosperm","synonyms":[{"name":"gamete recognition","type":"broad"},{"name":"male-female gamete recognition","type":"exact"}],"termid":"GO:0080173"}


id: GO:0010410
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present.","definition_xrefs":["GOC:tair_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell wall polysaccharide metabolic process","termid":"GO:0010383"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"part_of","termid":"GO:0071554"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0071554","GO:0008150","GO:0005975"],"is_obsolete":false,"name":"hemicellulose metabolic process","synonyms":[{"name":"hemicellulose metabolism","type":"exact"}],"termid":"GO:0010410"}


id: GO:0098985
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"asymmetric synapse","termid":"GO:0032279"},{"relation_name":"is_a","term_name":"excitatory synapse","termid":"GO:0060076"},{"relation_name":"is_a","term_name":"glutamatergic synapse","termid":"GO:0098978"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"asymmetric, glutamatergic, excitatory synapse","termid":"GO:0098985"}


id: GO:0045932
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of muscle contraction","termid":"GO:0006937"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"negatively_regulates","term_name":"muscle contraction","termid":"GO:0006936"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of muscle contraction","synonyms":[{"name":"down regulation of muscle contraction","type":"exact"},{"name":"down-regulation of muscle contraction","type":"exact"},{"name":"downregulation of muscle contraction","type":"exact"},{"name":"inhibition of muscle contraction","type":"narrow"}],"termid":"GO:0045932"}


id: GO:0004871
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete signal transducer activity (obsolete GO:0004871)","synonyms":[{"name":"hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity","type":"narrow"},{"name":"quorum sensing response regulator activity","type":"narrow"},{"name":"quorum sensing signal generator activity","type":"narrow"}],"termid":"GO:0004871"}


id: PBO:0029066
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_riboflavin_binding","termid":"PBO:0029066"}


id: PBO:0015229
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complement S. cerevisiae CET1 when coexpressed with pombe ceg1","termid":"PBO:0015229"}


id: MONDO:0007356
data:
  {"annotated_genes":["SJAG_02226"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86333],"is_not":false,"summary":null,"term":"MONDO:0007356"}]},"cv_name":"mondo","definition":"Any Lynch syndrome in which the cause of the disease is a mutation in the MSH2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"Lynch syndrome","termid":"MONDO:0005835"},{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"hereditary nonpolyposis colon cancer","termid":"MONDO:0018630"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02226":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"Lynch syndrome 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:120435","UMLS:C2936783","MEDGEN:423615","DOID:0070271","MESH:C537261","NCIT:C6725","GARD:15052"],"synonyms":[{"name":"COCA1","type":"related"},{"name":"HNPCC1","type":"exact"},{"name":"Hereditary non-polyposis colon cancer type 1","type":"exact"},{"name":"LYNCH syndrome I","type":"related"},{"name":"Lynch 1 syndrome","type":"exact"},{"name":"Lynch syndrome 1","type":"exact"},{"name":"Lynch syndrome 2","type":"related"},{"name":"Lynch syndrome type 1","type":"exact"},{"name":"colon cancer, familial nonpolyposis, type 1","type":"related"},{"name":"colorectal cancer, hereditary nonpolyposis, type 1","type":"related"},{"name":"familial non-polyposis colon cancer type 1","type":"exact"},{"name":"hereditary nonpolyposis colorectal cancer type 1","type":"exact"}],"termid":"MONDO:0007356","terms_by_termid":{"MONDO:0007356":null},"xrefs":{"Monarch":{"xref_id":"0007356"}}}


id: PBO:0088516
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-type ATPase V0 subunit a","termid":"PBO:0088516"}


id: GO:0030242
data:
  {"annotated_genes":["SJAG_04552","SJAG_01783","SJAG_05017","SJAG_03851","SJAG_04502","SJAG_04963","SJAG_00115","SJAG_00114"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79760,72072,72951,79665,71712,71365,77177,73371],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000425"}]},"cv_name":"biological_process","definition":"The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.","definition_xrefs":["PMID:20083110","GOC:autophagy","PMID:10547367"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autophagy","termid":"GO:0006914"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00114":null,"SJAG_00115":null,"SJAG_01783":null,"SJAG_03851":null,"SJAG_04502":null,"SJAG_04552":null,"SJAG_04963":null,"SJAG_05017":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006914"}],"interesting_parent_ids":["GO:0008150","GO:0006914"],"is_obsolete":false,"name":"autophagy of peroxisome","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"peroxisome degradation","type":"broad"},{"name":"peroxisome disassembly","type":"broad"},{"name":"pexophagy","type":"related"}],"termid":"GO:0030242","terms_by_termid":{"GO:0000425":null}}


id: PBO:0003956
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucan-alpha-1,4-glucosidase","termid":"PBO:0003956"}


id: PR:P41891
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- gar2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P41891"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein gar2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC140.02","synonyms":[{"name":"Spom972h-gar2","type":"exact"}],"termid":"PR:P41891"}


id: PATO:0001968
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A branched quality inhering in a bearer by virtue of the bearer's having two or more parallel primary branches originate beside each other and converge apically.","definition_xrefs":["Hickey:1988"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branched","termid":"PATO:0000402"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"parallelodromous","termid":"PATO:0001968"}


id: MONDO:0020260
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete myasthenic syndrome with eye involvement (obsolete MONDO:0020260)","secondary_identifiers":["Orphanet:98690"],"termid":"MONDO:0020260","xrefs":{"Monarch":{"xref_id":"0020260"}}}


id: PBO:0059532
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded tRNA-Asp (GAU/C)","termid":"PBO:0059532"}


id: GO:0050688
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to biotic stimulus","termid":"GO:0002831"},{"relation_name":"is_a","term_name":"regulation of defense response","termid":"GO:0031347"},{"relation_name":"is_a","term_name":"regulation of response to external stimulus","termid":"GO:0032101"},{"relation_name":"regulates","term_name":"defense response to virus","termid":"GO:0051607"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of defense response to virus","synonyms":[{"name":"regulation of antiviral response","type":"exact"}],"termid":"GO:0050688"}


id: GO:1905445
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of clathrin coat assembly.","definition_xrefs":["GO_REF:0000058","GOC:PARL","PMID:15533940","GOC:TermGenie","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein-containing complex assembly","termid":"GO:0031334"},{"relation_name":"is_a","term_name":"regulation of clathrin coat assembly","termid":"GO:1905443"},{"relation_name":"positively_regulates","term_name":"clathrin coat assembly","termid":"GO:0048268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0065003"},{"rel_name":"positively_regulates","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"positive regulation of clathrin coat assembly","synonyms":[{"name":"activation of clathrin cage assembly","type":"narrow"},{"name":"activation of clathrin coat assembly","type":"narrow"},{"name":"positive regulation of clathrin cage assembly","type":"exact"},{"name":"up regulation of clathrin cage assembly","type":"exact"},{"name":"up regulation of clathrin coat assembly","type":"exact"},{"name":"up-regulation of clathrin cage assembly","type":"exact"},{"name":"up-regulation of clathrin coat assembly","type":"exact"},{"name":"upregulation of clathrin cage assembly","type":"exact"},{"name":"upregulation of clathrin coat assembly","type":"exact"}],"termid":"GO:1905445"}


id: GO:0071576
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.","definition_xrefs":["GOC:mah","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tetrahydrobiopterin binding","termid":"GO:0034617"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"tetrahydrodictyopterin binding","synonyms":[{"name":"D-threo-tetrahydrobiopterin","type":"exact"},{"name":"DH4 binding","type":"exact"}],"termid":"GO:0071576"}


id: PBO:0063989
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 23","termid":"PBO:0063989"}


id: GO:1901032
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.","definition_xrefs":["GOC:kmv","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to reactive oxygen species","termid":"GO:1901031"},{"relation_name":"is_a","term_name":"negative regulation of response to oxidative stress","termid":"GO:1902883"},{"relation_name":"negatively_regulates","term_name":"response to reactive oxygen species","termid":"GO:0000302"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of response to reactive oxygen species","synonyms":[{"name":"down regulation of response to AOS","type":"exact"},{"name":"down regulation of response to ROI","type":"exact"},{"name":"down regulation of response to ROS","type":"exact"},{"name":"down regulation of response to active oxygen species","type":"exact"},{"name":"down regulation of response to reactive oxidative species","type":"exact"},{"name":"down regulation of response to reactive oxygen intermediate","type":"exact"},{"name":"down regulation of response to reactive oxygen species","type":"exact"},{"name":"down-regulation of response to AOS","type":"exact"},{"name":"down-regulation of response to ROI","type":"exact"},{"name":"down-regulation of response to ROS","type":"exact"},{"name":"down-regulation of response to active oxygen species","type":"exact"},{"name":"down-regulation of response to reactive oxidative species","type":"exact"},{"name":"down-regulation of response to reactive oxygen intermediate","type":"exact"},{"name":"down-regulation of response to reactive oxygen species","type":"exact"},{"name":"downregulation of response to AOS","type":"exact"},{"name":"downregulation of response to ROI","type":"exact"},{"name":"downregulation of response to ROS","type":"exact"},{"name":"downregulation of response to active oxygen species","type":"exact"},{"name":"downregulation of response to reactive oxidative species","type":"exact"},{"name":"downregulation of response to reactive oxygen intermediate","type":"exact"},{"name":"downregulation of response to reactive oxygen species","type":"exact"},{"name":"inhibition of response to AOS","type":"exact"},{"name":"inhibition of response to ROI","type":"exact"},{"name":"inhibition of response to ROS","type":"exact"},{"name":"inhibition of response to active oxygen species","type":"exact"},{"name":"inhibition of response to reactive oxidative species","type":"exact"},{"name":"inhibition of response to reactive oxygen intermediate","type":"exact"},{"name":"inhibition of response to reactive oxygen species","type":"narrow"},{"name":"negative regulation of response to AOS","type":"exact"},{"name":"negative regulation of response to ROI","type":"exact"},{"name":"negative regulation of response to ROS","type":"exact"},{"name":"negative regulation of response to active oxygen species","type":"exact"},{"name":"negative regulation of response to reactive oxidative species","type":"exact"},{"name":"negative regulation of response to reactive oxygen intermediate","type":"exact"}],"termid":"GO:1901032"}


id: GO:0006505
data:
  {"annotated_genes":["SJAG_03292","SJAG_06425","SJAG_03115","SJAG_06383","SJAG_02523","SJAG_04119","SJAG_01227","SJAG_02913","SJAG_01860","SJAG_02488","SJAG_03066","SJAG_03506","SJAG_04924","SJAG_05327","SJAG_00295","SJAG_04881","SJAG_03878","SJAG_03801","SJAG_04975","SJAG_02776","SJAG_04165","SJAG_01570","SJAG_05278","SJAG_00846","SJAG_03672","SJAG_01416","SJAG_00506","SJAG_00068","SJAG_00831","SJAG_04337","SJAG_02804"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72643,73015,77731,76420,69662,77464,60411,58356,58194,76317,77454,77461,77821,87390,103712,75495,74739,63056,73203,62481,58241,63397,57841,75518,77011,89508,78198,103774,92964,71691],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006506"},{"annotations":[73651],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006676"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycolipid metabolic process","termid":"GO:0006664"},{"relation_name":"is_a","term_name":"phosphatidylinositol metabolic process","termid":"GO:0046488"}],"gene_count":31,"genes_by_uniquename":{"SJAG_00068":null,"SJAG_00295":null,"SJAG_00506":null,"SJAG_00831":null,"SJAG_00846":null,"SJAG_01227":null,"SJAG_01416":null,"SJAG_01570":null,"SJAG_01860":null,"SJAG_02488":null,"SJAG_02523":null,"SJAG_02776":null,"SJAG_02804":null,"SJAG_02913":null,"SJAG_03066":null,"SJAG_03115":null,"SJAG_03292":null,"SJAG_03506":null,"SJAG_03672":null,"SJAG_03801":null,"SJAG_03878":null,"SJAG_04119":null,"SJAG_04165":null,"SJAG_04337":null,"SJAG_04881":null,"SJAG_04924":null,"SJAG_04975":null,"SJAG_05278":null,"SJAG_05327":null,"SJAG_06383":null,"SJAG_06425":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"GPI anchor metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0046472"],"synonyms":[{"name":"GPI anchor metabolism","type":"exact"},{"name":"GPI/GSI anchor metabolic process","type":"broad"},{"name":"GPI/GSI anchor metabolism","type":"broad"},{"name":"glycosylphosphatidylinositol metabolic process","type":"exact"},{"name":"glycosylphosphatidylinositol metabolism","type":"exact"}],"termid":"GO:0006505","terms_by_termid":{"GO:0006506":null,"GO:0006676":null}}


id: PBO:0070108
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 22 pseudogene","termid":"PBO:0070108"}


id: MONDO:0017460
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Syndactyly type 6 is a rare, genetic, non-syndromic, congenital limb malformation characterized by unilateral fusion of second to fifth fingers, amalgamation of distal phalanges in a knot-like structure, and second- and third-toe fusion. Some individuals present only with webbing between second and third toes, without involvement of fingers.","definition_xrefs":["Orphanet:295012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic syndactyly","termid":"MONDO:0019530"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syndactyly type 6","secondary_identifiers":["UMLS:C4706525","GARD:21201","MEDGEN:1635950","SCTID:763624007","icd11.foundation:2105806379"],"synonyms":[{"name":"mitten hand","type":"exact"},{"name":"syndactyly, mitten type","type":"exact"},{"name":"unilateral syndactyly of digits 2-5","type":"exact"}],"termid":"MONDO:0017460","xrefs":{"Monarch":{"xref_id":"0017460"}}}


id: GO:1905437
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation.","definition_xrefs":["GOC:TermGenie","PMID:27541139","GO_REF:0000058"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of histone H3-K4 trimethylation (obsolete GO:1905437)","synonyms":[{"name":"activation of histone H3-K4 trimethylation","type":"narrow"},{"name":"up regulation of histone H3-K4 trimethylation","type":"exact"},{"name":"up-regulation of histone H3-K4 trimethylation","type":"exact"},{"name":"upregulation of histone H3-K4 trimethylation","type":"exact"}],"termid":"GO:1905437"}


id: GO:0042615
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to CD154, a receptor found on the surface of some activated lymphocytes.","definition_xrefs":["ISBN:0120781859","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signaling receptor binding","termid":"GO:0005102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"CD154 receptor binding","synonyms":[{"name":"CD40 receptor activity","type":"related"},{"name":"CD40L binding","type":"exact"}],"termid":"GO:0042615"}


id: MONDO:0007000
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An disease caused by infection with Treponema.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial sexually transmitted disease","termid":"MONDO:0005323"},{"relation_name":"is_a","term_name":"gram-negative bacterial infections","termid":"MONDO:0021678"},{"relation_name":"is_a","term_name":"spirochaetales infections","termid":"MONDO:0021839"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Treponema infectious disease","secondary_identifiers":["EFO:1001217","MESH:D014211","NCIT:C85197"],"synonyms":[{"name":"Bejels","type":"narrow"},{"name":"Treponema caused disease or disorder","type":"exact"},{"name":"Treponema disease or disorder","type":"exact"},{"name":"Treponemal infection","type":"related"},{"name":"bejel","type":"narrow"},{"name":"infection, Treponemal","type":"related"},{"name":"infections, Treponemal","type":"related"}],"termid":"MONDO:0007000","xrefs":{"Monarch":{"xref_id":"0007000"}}}


id: MONDO:0020270
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pigmentation disorder with eye involvement (obsolete MONDO:0020270)","secondary_identifiers":["Orphanet:98700"],"termid":"MONDO:0020270","xrefs":{"Monarch":{"xref_id":"0020270"}}}


id: PR:Q9HDZ5
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- csr101 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9HDZ5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CRAL-TRIO domain-containing protein C589.09, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC589.09","synonyms":[{"name":"Spom972h-csr101","type":"exact"}],"termid":"PR:Q9HDZ5"}


id: PBO:0052351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin family member 4A","termid":"PBO:0052351"}


id: PBO:0046326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enolase 4","termid":"PBO:0046326"}


id: MONDO:0012336
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the CRYBB3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset non-syndromic cataract","termid":"MONDO:0011060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cataract 22 multiple types","secondary_identifiers":["OMIM:609741","MESH:C565725","DOID:0110268","UMLS:C1857853","MEDGEN:341862"],"synonyms":[{"name":"CATCN2","type":"narrow"},{"name":"CRYBB3 early-onset non-syndromic cataract","type":"exact"},{"name":"CTRCT22","type":"exact"},{"name":"autosomal recessive congenital nuclear cataract 2","type":"narrow"},{"name":"cataract 22","type":"exact"},{"name":"cataract 22, multiple types","type":"related"},{"name":"cataract, congenital nuclear, autosomal recessive 2","type":"related"},{"name":"early-onset non-syndromic cataract caused by mutation in CRYBB3","type":"exact"}],"termid":"MONDO:0012336","xrefs":{"Monarch":{"xref_id":"0012336"}}}


id: PBO:0042044
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 97","termid":"PBO:0042044"}


id: PBO:0006192
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_presence_of","termid":"PBO:0006192"}


id: PBO:0042107
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 180","termid":"PBO:0042107"}


id: RO:0002177
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.","direct_ancestors":[{"relation_name":"is_a","term_name":"mereotopologically_related_to","termid":"RO:0002323"},{"relation_name":"is_a","term_name":"biomechanically_related_to","termid":"RO:0002567"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"attached_to_part_of","termid":"RO:0002177"}


id: PR:O42918
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- meu7 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42918"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-amylase 4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16A3.13","synonyms":[{"name":"1,4-alpha-D-glucan glucanohydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-meu7","type":"exact"},{"name":"meiotic expression up-regulated protein 7 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42918"}


id: PBO:0085455
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Potassium transporter that mediates K+ influx; activates high-affinity Ca2+ influx system (HACS) during mating pheromone response; expression up-regulated in response to alpha factor; localized to sites of polarized growth; member of a fungal-specific gene family; potential Cdc28p substrate; KCH1 has a paralog, PRM6, that arose from the whole genome duplication","termid":"PBO:0085455"}


id: MONDO:0000246
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete la Crosse encephalitis (obsolete MONDO:0000246)","termid":"MONDO:0000246","xrefs":{"Monarch":{"xref_id":"0000246"}}}


id: GO:0005859
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A filament of myosin found in a muscle cell of any type.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myosin II complex","termid":"GO:0016460"},{"relation_name":"part_of","term_name":"contractile muscle fiber","termid":"GO:0043292"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0015629"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0015629","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"muscle myosin complex","termid":"GO:0005859"}


id: PBO:0029955
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_microtubule_binding","termid":"PBO:0029955"}


id: GO:0170022
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of an ion by a channel that opens when a specific bitter compound has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["PMID:21262465"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ionotropic taste receptor activity","termid":"GO:0170021"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674","GO:0038023"],"is_obsolete":false,"name":"ionotropic bitter taste receptor activity","termid":"GO:0170022"}


id: GO:0018334
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine.","definition_xrefs":["RESID:AA0039"],"gene_count":0,"genotype_count":0,"name":"obsolete enzyme active site formation via O4'-phospho-L-tyrosine (obsolete GO:0018334)","termid":"GO:0018334"}


id: PBO:0050688
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 8 pseudogene 15","termid":"PBO:0050688"}


id: MONDO:0010973
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the GSDME gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 5","secondary_identifiers":["MEDGEN:331398","UMLS:C1832932","OMIM:600994","GARD:18102","MESH:C563410","DOID:0110575"],"synonyms":[{"name":"DFNA5","type":"narrow"},{"name":"GSDME autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"autosomal dominant deafness 5","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 5","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in GSDME","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 5","type":"narrow"},{"name":"deafness, autosomal dominant 5","type":"narrow"},{"name":"deafness, autosomal dominant type 5","type":"narrow"}],"termid":"MONDO:0010973","xrefs":{"Monarch":{"xref_id":"0010973"}}}


id: MOD:01727
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"The protein modification reporter fragment produced by an Proteome Sciences TMT6plex-126 reagent acylated residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"TMT6plex-126 reporter+balance reagent acylated residue","termid":"MOD:01720"},{"relation_name":"derives_from","term_name":"cysTMT6plex-zero reporter+balance reagent cysteine disulfide","termid":"MOD:01822"},{"relation_name":"derives_from","term_name":"cysTMT6plex-126 reporter+balance reagent cysteine disulfide","termid":"MOD:01823"},{"relation_name":"is_a","term_name":"TMT6plex reporter fragment","termid":"MOD:01716"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-126 reporter fragment","synonyms":[{"name":"2,6-dimethyl-1-methylidenepiperidinium","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"},{"name":"cysTMT6plex-126 reporter fragment","type":"exact"}],"termid":"MOD:01727"}


id: PBO:0000829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase Ryh1","termid":"PBO:0000829"}


id: PBO:0030460
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_biotin_import","termid":"PBO:0030460"}


id: PBO:0087315
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stress","termid":"PBO:0087315"}


id: GO:0016088
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete insulin (obsolete GO:0016088)","synonyms":[{"name":"insulin","type":"exact"}],"termid":"GO:0016088"}


id: MONDO:0014798
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any brachydactyly type A1 in which the cause of the disease is a mutation in the BMPR1B gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"brachydactyly type A1","termid":"MONDO:0007215"},{"relation_name":"is_a","term_name":"brachydactyly","termid":"MONDO:0021004"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brachydactyly type A1D","secondary_identifiers":["OMIM:616849","GARD:16164","MEDGEN:903193","DOID:0110978","UMLS:C4225183"],"synonyms":[{"name":"BDA1D","type":"exact"},{"name":"BMPR1B brachydactyly type A1","type":"exact"},{"name":"brachydactyly type A1 caused by mutation in BMPR1B","type":"exact"},{"name":"brachydactyly, type A1, D","type":"exact"}],"termid":"MONDO:0014798","xrefs":{"Monarch":{"xref_id":"0014798"}}}


id: PBO:0085058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol","termid":"PBO:0085058"}


id: PBO:0004392
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homoserine dehydrogenase (predicted)","termid":"PBO:0004392"}


id: GO:1990394
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.","definition_xrefs":["PMID:17287531"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to stimulus","termid":"GO:0051716"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to cell wall damage","termid":"GO:1990394"}


id: GO:0140745
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The transcription of a small interfering RNA from an RNA template.","definition_xrefs":["PMID:23001036"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA-templated transcription","termid":"GO:0001172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"siRNA transcription","termid":"GO:0140745"}


id: PBO:0072087
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S12 pseudogene 17","termid":"PBO:0072087"}


id: GO:0036494
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.","definition_xrefs":["GOC:PARL","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of translational initiation in response to stress","termid":"GO:0032058"},{"relation_name":"is_a","term_name":"regulation of translation initiation in response to endoplasmic reticulum stress","termid":"GO:0036491"},{"relation_name":"is_a","term_name":"positive regulation of translation in response to endoplasmic reticulum stress","termid":"GO:0036493"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of translation initiation in response to endoplasmic reticulum stress","synonyms":[{"name":"positive regulation of translation initiation in response to ER stress","type":"exact"}],"termid":"GO:0036494"}


id: MONDO:0957221
data:
  {"annotated_genes":["SJAG_01159"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86493],"is_not":false,"summary":null,"term":"MONDO:0957221"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary spastic paraplegia","termid":"MONDO:0019064"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01159":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"spastic paraplegia 70, autosomal recessive","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:620323","DOID:0070454"],"termid":"MONDO:0957221","terms_by_termid":{"MONDO:0957221":null},"xrefs":{"Monarch":{"xref_id":"0957221"}}}


id: PBO:0005859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Puf family RNA-binding protein Puf6 (predicted)","termid":"PBO:0005859"}


id: GO:1900520
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of response to pullulan.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of response to stimulus","termid":"GO:0048584"},{"relation_name":"is_a","term_name":"regulation of response to pullulan","termid":"GO:1900518"},{"relation_name":"positively_regulates","term_name":"response to pullulan","termid":"GO:0044592"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of response to pullulan","synonyms":[{"name":"activation of response to pullulan","type":"narrow"},{"name":"up regulation of response to pullulan","type":"exact"},{"name":"up-regulation of response to pullulan","type":"exact"},{"name":"upregulation of response to pullulan","type":"exact"}],"termid":"GO:1900520"}


id: MONDO:0006701
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells do not stain with acidic or basic dyes.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pituitary gland adenoma","termid":"MONDO:0006373"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromophobe adenoma","secondary_identifiers":["DOID:3828","UMLS:C0001432","EFO:1000867","ICDO:8270/0","MEDGEN:1747","MESH:D000238","NCIT:C2857"],"synonyms":[{"name":"chromophobe adenoma of pituitary gland","type":"exact"},{"name":"chromophobe adenoma of the pituitary gland","type":"exact"},{"name":"pituitary chromophobe adenoma","type":"exact"},{"name":"pituitary gland chromophobe adenoma","type":"exact"}],"termid":"MONDO:0006701","xrefs":{"Monarch":{"xref_id":"0006701"}}}


id: SO:0001502
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An experimental feature with high sequence identity to another sequence.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"experimental_feature","termid":"SO:0001410"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high_identity_region","synonyms":[{"name":"high identity region","type":"exact"}],"termid":"SO:0001502"}


id: PBO:0000088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved fungal family","termid":"PBO:0000088"}


id: PBO:0049339
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"general transcription factor IIH subunit 4","termid":"PBO:0049339"}


id: FYPO:0008288
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a ceramide measured in a cell higher than normal.","definition_xrefs":["PomBase:pc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of substance in cell during vegetative growth","termid":"FYPO:0001330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular ceramide level","termid":"FYPO:0008288"}


id: MONDO:0859305
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with eye movement abnormalities and ataxia","secondary_identifiers":["UMLS:C5774241","MEDGEN:1824014","DOID:0081275","OMIM:620094"],"termid":"MONDO:0859305","xrefs":{"Monarch":{"xref_id":"0859305"}}}


id: PBO:0108599
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-negatively_regulates_characteristic","termid":"PBO:0108599"}


id: PBO:0018083
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribose methyltransferase Mrm1 (predicted)","termid":"PBO:0018083"}


id: PBO:0083266
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 75% of ORF overlaps the verified gene SFH1; deletion causes a vacuolar protein sorting defect and blocks anaerobic growth","termid":"PBO:0083266"}


id: MONDO:0026727
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Shukla-Vernon syndrome","secondary_identifiers":["UMLS:C5193146","OMIM:301029","MEDGEN:1674076","GARD:18511","DOID:0111841"],"synonyms":[{"name":"SHUKLA-VERNON SYNDROME","type":"related"},{"name":"SHUVER","type":"related"},{"name":"Shukla-Vernon syndrome, X-linked recessive","type":"exact"}],"termid":"MONDO:0026727","xrefs":{"Monarch":{"xref_id":"0026727"}}}


id: PBO:0078044
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 34","termid":"PBO:0078044"}


id: SO:0001988
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A 5' UTR variant where a premature start codon is gained.","definition_xrefs":["Sanger:am"],"direct_ancestors":[{"relation_name":"is_a","term_name":"5_prime_UTR_premature_start_codon_variant","termid":"SO:0001983"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5_prime_UTR_premature_start_codon_gain_variant","secondary_identifiers":["http://snpeff.sourceforge.net/SnpEff_manual.html"],"synonyms":[{"name":"5 prime UTR premature start codon gain variant","type":"exact"},{"name":"Jannovar:5_prime_UTR_premature_start_codon_gain_variant","type":"exact"},{"name":"snpEff:START_GAINED","type":"exact"}],"termid":"SO:0001988"}


id: PBO:0062780
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 56 subfamily B member 2 pseudogene","termid":"PBO:0062780"}


id: PR:P87144
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A threonyl-tRNA synthetase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03641","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"threonine--tRNA ligase, cytoplasmic (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC25H2.02","secondary_identifiers":["UniProtKB:P87144"],"synonyms":[{"name":"Spom972h-thrS","type":"exact"},{"name":"ThrRS (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"threonyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P87144"}


id: PR:Q9C106
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA-directed RNA polymerase III subunit RPC3 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR12949:SF0","OMA:SCHPO01373","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III subunit rpc3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB1E7.03","secondary_identifiers":["UniProtKB:Q9C106"],"synonyms":[{"name":"RNA polymerase III subunit C3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RNA polymerase III subunit C82 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-POLR3C","type":"exact"}],"termid":"PR:Q9C106"}


id: MONDO:0015680
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Rare pervasive developmental disorder.","gene_count":0,"genotype_count":0,"name":"obsolete rare pervasive developmental disorder (obsolete MONDO:0015680)","secondary_identifiers":["Orphanet:168778","MedDRA:10061345"],"synonyms":[{"name":"rare ASD","type":"narrow"},{"name":"rare PDD","type":"narrow"},{"name":"rare autism spectrum disorder","type":"narrow"},{"name":"rare pervasive developmental disorder","type":"narrow"}],"termid":"MONDO:0015680","xrefs":{"Monarch":{"xref_id":"0015680"}}}


id: PBO:0114320
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces pombe specific protein, ubiquitin conjugatiing enzyme-like","termid":"PBO:0114320"}


id: GO:0015110
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane transporter activity","termid":"GO:0022857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"cyanate transmembrane transporter activity","termid":"GO:0015110"}


id: PBO:0074894
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 69","termid":"PBO:0074894"}


id: PBO:0049819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone deacetylase 10","termid":"PBO:0049819"}


id: GO:1903571
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling.","definition_xrefs":["GOC:BHF","GOC:rl","GOC:TermGenie","PMID:20497126","GO_REF:0000058"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of protein kinase D signaling (obsolete GO:1903571)","synonyms":[{"name":"down regulation of PKD signal transduction","type":"exact"},{"name":"down regulation of PKD signaling cascade","type":"related"},{"name":"down regulation of protein kinase D signal transduction","type":"exact"},{"name":"down regulation of protein kinase D signaling","type":"exact"},{"name":"down regulation of protein kinase D signaling cascade","type":"related"},{"name":"down regulation of protein kinase D signalling cascade","type":"related"},{"name":"down-regulation of PKD signal transduction","type":"exact"},{"name":"down-regulation of PKD signaling cascade","type":"related"},{"name":"down-regulation of protein kinase D signal transduction","type":"exact"},{"name":"down-regulation of protein kinase D signaling","type":"exact"},{"name":"down-regulation of protein kinase D signaling cascade","type":"related"},{"name":"down-regulation of protein kinase D signalling cascade","type":"related"},{"name":"downregulation of PKD signal transduction","type":"exact"},{"name":"downregulation of PKD signaling cascade","type":"related"},{"name":"downregulation of protein kinase D signal transduction","type":"exact"},{"name":"downregulation of protein kinase D signaling","type":"exact"},{"name":"downregulation of protein kinase D signaling cascade","type":"related"},{"name":"downregulation of protein kinase D signalling cascade","type":"related"},{"name":"inhibition of PKD signal transduction","type":"narrow"},{"name":"inhibition of PKD signaling cascade","type":"related"},{"name":"inhibition of protein kinase D signal transduction","type":"narrow"},{"name":"inhibition of protein kinase D signaling","type":"narrow"},{"name":"inhibition of protein kinase D signaling cascade","type":"related"},{"name":"inhibition of protein kinase D signalling cascade","type":"related"},{"name":"negative regulation of PKD signal transduction","type":"exact"},{"name":"negative regulation of PKD signaling cascade","type":"related"},{"name":"negative regulation of protein kinase D signal transduction","type":"exact"},{"name":"negative regulation of protein kinase D signaling cascade","type":"related"},{"name":"negative regulation of protein kinase D signalling cascade","type":"related"}],"termid":"GO:1903571"}


id: GO:0001533
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes).","definition_xrefs":["GOC:add","PMID:11112355","PMID:15803139","PMID:11590230"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane","termid":"GO:0005886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"cornified envelope","termid":"GO:0001533"}


id: PBO:0071765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein lateral stalk subunit P1 pseudogene 12","termid":"PBO:0071765"}


id: PBO:0050538
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"haptoglobin-related protein","termid":"PBO:0050538"}


id: PBO:0004498
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RSC complex subunit Rsc1","termid":"PBO:0004498"}


id: PBO:0043877
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cAMP responsive element binding protein 5","termid":"PBO:0043877"}


id: PR:O94693
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A CD2 cytoplasmic tail-binding protein 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR13138:SF3","PRO:DNx","OMA:SCHPO02904"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LIN1-like protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC83.09c","secondary_identifiers":["UniProtKB:O94693"],"synonyms":[{"name":"Spom972h-CD2BP2","type":"exact"}],"termid":"PR:O94693"}


id: MONDO:0002738
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute form of non-suppurative otitis media.","definition_xrefs":["MONDO:patterns/acute"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-suppurative otitis media","termid":"MONDO:0001212"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acute transudative otitis media","secondary_identifiers":["MEDGEN:543339","ICD9:381.00","SCTID:359609001","DOID:3697","UMLS:C0271432","ICD9:381.0"],"synonyms":[{"name":"acute non-suppurative otitis media","type":"exact"},{"name":"acute nonsuppurative otitis media","type":"exact"},{"name":"acute otitis media with effusion","type":"exact"},{"name":"acute secretory otitis media","type":"exact"},{"name":"acute transudative otitis media","type":"exact"},{"name":"non-suppurative otitis media, acute","type":"exact"}],"termid":"MONDO:0002738","xrefs":{"Monarch":{"xref_id":"0002738"}}}


id: GO:0098924
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retrograde trans-synaptic signaling by soluble gas","termid":"GO:0098923"},{"relation_name":"is_a","term_name":"trans-synaptic signaling by nitric oxide","termid":"GO:0099548"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"retrograde trans-synaptic signaling by nitric oxide","termid":"GO:0098924"}


id: GO:0050534
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.","definition_xrefs":["EC:3.2.1.144"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787","GO:0016798"],"is_obsolete":false,"name":"3-deoxyoctulosonase activity","secondary_identifiers":["MetaCyc:RXN-12002"],"synonyms":[{"name":"3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity","type":"related"},{"name":"alpha-Kdo-ase activity","type":"related"}],"termid":"GO:0050534"}


id: PBO:0089241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"human coilin ortholog Mug174","termid":"PBO:0089241"}


id: MONDO:0014002
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nocturnal frontal lobe epilepsy in which the cause of the disease is a mutation in the KCNT1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sleep-related hypermotor epilepsy","termid":"MONDO:0000030"},{"relation_name":"is_a","term_name":"autosomal dominant nocturnal frontal lobe epilepsy","termid":"MONDO:0020300"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"autosomal dominant nocturnal frontal lobe epilepsy 5","secondary_identifiers":["OMIM:615005","UMLS:C3554306","MEDGEN:767220","DOID:0060686","GARD:15891"],"synonyms":[{"name":"ENFL5","type":"exact"},{"name":"KCNT1 autosomal dominant nocturnal frontal lobe epilepsy","type":"exact"},{"name":"autosomal dominant nocturnal frontal lobe epilepsy caused by mutation in KCNT1","type":"exact"},{"name":"autosomal dominant nocturnal frontal lobe epilepsy type 5","type":"exact"},{"name":"epilepsy nocturnal frontal lobe, 5","type":"exact"},{"name":"epilepsy, nocturnal frontal lobe, 5","type":"related"},{"name":"epilepsy, nocturnal frontal lobe, type 5","type":"exact"},{"name":"nocturnal frontal lobe epilepsy 5","type":"exact"}],"termid":"MONDO:0014002","xrefs":{"Monarch":{"xref_id":"0014002"}}}


id: GO:1904289
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint.","definition_xrefs":["PMID:16549501","GOC:kmv","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mitotic cell cycle","termid":"GO:0007346"},{"relation_name":"is_a","term_name":"regulation of DNA damage checkpoint","termid":"GO:2000001"},{"relation_name":"regulates","term_name":"mitotic DNA damage checkpoint signaling","termid":"GO:0044773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0007049","GO:0008150"],"is_obsolete":false,"name":"regulation of mitotic DNA damage checkpoint","termid":"GO:1904289"}


id: GO:0070893
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome.","definition_xrefs":["GOC:jp","PMID:10882723"],"gene_count":0,"genotype_count":0,"name":"obsolete transposon integration (obsolete GO:0070893)","termid":"GO:0070893"}


id: PR:O74341
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A T-complex protein 1 subunit gamma that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03080","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T-complex protein 1 subunit gamma (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1A4.08c","secondary_identifiers":["UniProtKB:O74341"],"synonyms":[{"name":"CCT-gamma (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-CCT3","type":"exact"},{"name":"TCP-1-gamma (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74341"}


id: PBO:0032756
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved fungal protein Aim19","termid":"PBO:0032756"}


id: SO:0001733
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A kind of histone modification site, whereby the 36th residue (a lysine), from the start of the H3 histone protein is methylated.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone_methylation_site","termid":"SO:0001701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"H3K36_methylation_site","synonyms":[{"name":"H3K36 methylation site","type":"exact"}],"termid":"SO:0001733"}


id: MONDO:0008926
data:
  {"annotated_genes":["SJAG_04114","SJAG_02828","SJAG_02031","SJAG_00995"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86820],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008955"},{"annotations":[85647],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012553"},{"annotations":[84976],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014696"},{"annotations":[85648],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012554"},{"annotations":[86551],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010216"}]},"cv_name":"mondo","definition":"Cerebrooculofacioskeletal (COFS) syndrome is a rare genetic disorder, belonging to a family of diseases of DNA repair, characterized by a severe sensorineural involvement.","definition_xrefs":["Orphanet:1466"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"Cockayne syndrome","termid":"MONDO:0016006"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"syndromic microphthalmia","termid":"MONDO:0016073"},{"relation_name":"is_a","term_name":"DNA repair disease","termid":"MONDO:0021190"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00995":null,"SJAG_02031":null,"SJAG_02828":null,"SJAG_04114":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021190"},{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005066","MONDO:0021190","MONDO:0005328"],"is_obsolete":false,"name":"COFS syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1762238","NCIT:C3817","NORD:913","GARD:6027","OMIMPS:214150","DOID:0080910","UMLS:C5399761"],"synonyms":[{"name":"COFS","type":"exact"},{"name":"Cerebro Oculo Facio Skeletal Syndrome","type":"exact"},{"name":"Pena-Shokeir syndrome type 2","type":"exact"},{"name":"cerebro-oculo-facio-skeletal syndrome","type":"exact"},{"name":"cerebrooculofacioskeletal syndrome","type":"exact"}],"termid":"MONDO:0008926","terms_by_termid":{"MONDO:0008955":null,"MONDO:0010216":null,"MONDO:0012553":null,"MONDO:0012554":null,"MONDO:0014696":null},"xrefs":{"Monarch":{"xref_id":"0008926"}}}


id: PBO:0087430
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm; protein abundance increases in response to DNA replication stress; human homolog ATP6V1B1, implicated in autosomal-recessive distal renal tubular acidosis (RTA) with sensorineural deafness, complements yeast null mutant","termid":"PBO:0087430"}


id: PBO:0048423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamyl-tRNA amidotransferase subunit B","termid":"PBO:0048423"}


id: PBO:0062468
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily E member 159 pseudogene","termid":"PBO:0062468"}


id: PBO:0052663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 8 pseudogene 31","termid":"PBO:0052663"}


id: MONDO:0100072
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neonatal diabetes, congenital sensorineural hearing loss and congenital cataracts is characterized by the three primary phenotypes of neonatal diabetes, congenital sensorineural hearing loss and congenital cataracts. Cases have reported additional varying phenotypes, including optic atrophy, hypothyroidism, severe neonatal hypotonia in males, developmental delay, facial abnormalities, and a few other more rare phenotypes. The severity and congenital onset of the phenotypes distinguish these patients from Wolfram-like syndrome patients.","definition_xrefs":["PMID:28468959","PMID:27217304"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neonatal diabetes, congenital sensorineural hearing loss and congenital cataracts","termid":"MONDO:0100072","xrefs":{"Monarch":{"xref_id":"0100072"}}}


id: SO:0000947
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region specifically recognized by a recombinase, which separates a physically contiguous circle of DNA into two physically separate circles.","definition_xrefs":["SO:as"],"direct_ancestors":[{"relation_name":"is_a","term_name":"site_specific_recombination_target_region","termid":"SO:0000342"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"resolution_site","synonyms":[{"name":"res site","type":"exact"},{"name":"resolution site","type":"exact"}],"termid":"SO:0000947"}


id: MONDO:0007505
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"earring holes, natural","secondary_identifiers":["UMLS:C1851895","MEDGEN:338809","OMIM:129000"],"synonyms":[{"name":"earlobe sinuses","type":"related"},{"name":"earring holes, natural","type":"exact"}],"termid":"MONDO:0007505","xrefs":{"Monarch":{"xref_id":"0007505"}}}


id: PBO:0050525
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homeobox D13","termid":"PBO:0050525"}


id: GO:0047787
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 3-oxo-5beta-steroid + NADP+ = a 3-oxo-Delta(4)-steroid + H+ + NADPH. The enzyme from human efficiently catalyzes the reduction of progesterone, androstenedione, 17alpha-hydroxyprogesterone and testosterone to 5beta-reduced metabolites; it can also act on aldosterone, corticosterone and cortisol, but to a lesser extent. The bile acid intermediates 7alpha,12alpha-dihydroxy-4-cholesten-3- one and 7alpha-hydroxy-4-cholesten-3-one can also act as substrates.","definition_xrefs":["EC:1.3.1.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enone reductase activity","termid":"GO:0035671"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"Delta4-3-oxosteroid 5beta-reductase activity","secondary_identifiers":["MetaCyc:RXN-23672","GO:0047752","RHEA:54412"],"synonyms":[{"name":"3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity","type":"exact"},{"name":"3-oxo-Delta(4)-steroid 5-beta-reductase activity","type":"exact"},{"name":"3-oxo-Delta4-steroid 5beta-reductase activity","type":"exact"},{"name":"4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity","type":"narrow"},{"name":"5-beta-reductase activity","type":"broad"},{"name":"5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity","type":"narrow"},{"name":"5beta-reductase activity","type":"related"},{"name":"Delta(4)-3-ketosteroid 5-beta-reductase activity","type":"related"},{"name":"Delta(4)-5-beta-reductase activity","type":"related"},{"name":"Delta(4)-hydrogenase activity","type":"related"},{"name":"Delta4-3-ketosteroid 5beta-reductase activity","type":"related"},{"name":"Delta4-3-oxosteroid 5-beta-reductase activity","type":"exact"},{"name":"Delta4-5beta-reductase activity","type":"related"},{"name":"Delta4-hydrogenase activity","type":"related"},{"name":"androstenedione 5-beta-reductase activity","type":"narrow"},{"name":"androstenedione 5beta-reductase activity","type":"narrow"},{"name":"cholestenone 5-beta-reductase activity","type":"narrow"},{"name":"cholestenone 5b-reductase activity","type":"narrow"},{"name":"cholestenone 5beta-reductase activity","type":"narrow"},{"name":"cortisone 5-beta-reductase activity","type":"narrow"},{"name":"cortisone 5beta-reductase activity","type":"narrow"},{"name":"cortisone b-reductase activity","type":"narrow"},{"name":"cortisone beta-reductase activity","type":"narrow"},{"name":"cortisone delta(4)-5-beta-reductase activity","type":"narrow"},{"name":"cortisone delta4-5beta-reductase activity","type":"related"},{"name":"steroid 5-beta-reductase activity","type":"related"},{"name":"steroid 5beta-reductase activity","type":"related"},{"name":"testosterone 5-beta-reductase activity","type":"narrow"},{"name":"testosterone 5beta-reductase activity","type":"narrow"}],"termid":"GO:0047787"}


id: PBO:0005167
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rik1-Associated Factor","termid":"PBO:0005167"}


id: PBO:0034179
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_homocracy_relationship_with","termid":"PBO:0034179"}


id: PBO:0067689
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5.8S ribosomal N1","termid":"PBO:0067689"}


id: PBO:0005777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U5 snRNP-associated protein Prp18 (predicted)","termid":"PBO:0005777"}


id: MONDO:0005530
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Disorders related or resulting from abuse or mis-use of opioids.","definition_xrefs":["MESH:D009293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"drug dependence","termid":"MONDO:0005303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"opiate dependence","secondary_identifiers":["EFO:0005611","ICD9:304.00","ICD9:304.0","DOID:2559","MEDGEN:99372","SCTID:75544000","UMLS:C0524662"],"synonyms":[{"name":"narcotism","type":"related"},{"name":"opioid dependence","type":"exact"},{"name":"opioid type dependence","type":"exact"}],"termid":"MONDO:0005530","xrefs":{"Monarch":{"xref_id":"0005530"}}}


id: PBO:0028435
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_superoxide_dismutase_activity","termid":"PBO:0028435"}


id: MONDO:0014791
data:
  {"annotated_genes":["SJAG_02873"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85751],"is_not":false,"summary":null,"term":"MONDO:0014791"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02873":null},"genotype_count":0,"is_obsolete":false,"name":"Luscan-Lumish syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:616831","Orphanet:597738","UMLS:C4085873","GARD:13789","MEDGEN:898669"],"synonyms":[{"name":"LLS","type":"exact"},{"name":"LLs","type":"exact"},{"name":"Luscan-Lumish syndrome","type":"exact"},{"name":"Luscan-Lumish syndrome; LLs","type":"exact"},{"name":"SETD2-related overgrowth syndrome","type":"exact"}],"termid":"MONDO:0014791","terms_by_termid":{"MONDO:0014791":null},"xrefs":{"Monarch":{"xref_id":"0014791"}}}


id: GO:0120538
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ = 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O.","definition_xrefs":["PMID:38425362","RHEA:81183"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016713"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"2-methoxy-6-polyprenolphenol 4-hydroxylase activity","termid":"GO:0120538"}


id: PBO:0082392
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Beta' regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase","termid":"PBO:0082392"}


id: GO:0019631
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"quinate metabolic process","termid":"GO:0019630"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044248","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"quinate catabolic process","secondary_identifiers":["MetaCyc:QUINATEDEG-PWY"],"synonyms":[{"name":"quinate breakdown","type":"exact"},{"name":"quinate catabolism","type":"exact"},{"name":"quinate degradation","type":"exact"},{"name":"quinic acid catabolic process","type":"exact"},{"name":"quinic acid catabolism","type":"exact"}],"termid":"GO:0019631"}


id: PR:Q9USG6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rpl35a gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9USG6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L33-B (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCP31B10.08c","synonyms":[{"name":"L37B (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-rpl35a","type":"exact"}],"termid":"PR:Q9USG6"}


id: GO:0042214
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoprenoid metabolic process","termid":"GO:0006720"},{"relation_name":"is_a","term_name":"hydrocarbon metabolic process","termid":"GO:0120252"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"terpene metabolic process","synonyms":[{"name":"terpene metabolism","type":"exact"}],"termid":"GO:0042214"}


id: PBO:0032767
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ark1 kinase consensus phosphorylation site is [RK]-X-[ST]","termid":"PBO:0032767"}


id: GO:0140999
data:
  {"annotated_genes":["SJAG_00769"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[58619],"is_not":false,"summary":null,"term":"GO:0140999"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysyl4-[histone H3] + 3 S-adenosyl-L-methionine = 2 H+ + N6,N6-trimethyl-L-lysyl4-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me3.","definition_xrefs":["RHEA:60260","PMID:18375658"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H3K4 methyltransferase activity","termid":"GO:0042800"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00769":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"}],"interesting_parent_ids":["GO:0008276","GO:0003824","GO:0016741","GO:0003674","GO:0016740","GO:0140096"],"is_obsolete":false,"name":"histone H3K4 trimethyltransferase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["EC:2.1.1.354"],"synonyms":[{"name":"histone H3-K4 trimethylation","type":"broad"},{"name":"histone H3K4 trimethylase activity","type":"exact"},{"name":"histone H3K4 trimethylation","type":"broad"},{"name":"histone lysine N-trimethyltransferase activity (H3-K4 specific)","type":"exact"}],"termid":"GO:0140999","terms_by_termid":{"GO:0140999":null}}


id: GO:0046245
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete styrene biosynthetic process (obsolete GO:0046245)","synonyms":[{"name":"styrene anabolism","type":"exact"},{"name":"styrene biosynthesis","type":"exact"},{"name":"styrene biosynthetic process","type":"exact"},{"name":"styrene formation","type":"exact"},{"name":"styrene synthesis","type":"exact"}],"termid":"GO:0046245"}


id: PBO:0001275
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA (m1A) methyltransferase complex catalytic subunit Cpd1","termid":"PBO:0001275"}


id: GO:1902698
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of pentose to butyrate.","definition_xrefs":["PMID:19539744","GO_REF:0000093","GOC:mengo_curators","PMID:18727018","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete pentose catabolic process to butyrate (obsolete GO:1902698)","synonyms":[{"name":"acidogenesis","type":"broad"},{"name":"pentose breakdown to butyrate","type":"exact"},{"name":"pentose catabolism to butyrate","type":"exact"},{"name":"pentose degradation to butyrate","type":"exact"}],"termid":"GO:1902698"}


id: PBO:0017977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"6-phosphofructokinase pfk1","termid":"PBO:0017977"}


id: PBO:0005579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone chaperone Cia1","termid":"PBO:0005579"}


id: MONDO:0018870
data:
  {"annotated_genes":["SJAG_01344","SJAG_03785","SJAG_05213"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86615,86614,86616],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013768"}]},"cv_name":"mondo","definition":"Idiopathic arterial calcification of infancy is a rare condition characterized by extensive calcification and stenosis of the large and medium sized arteries.","definition_xrefs":["Orphanet:51608"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"vascular disorder","termid":"MONDO:0005385"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01344":null,"SJAG_03785":null,"SJAG_05213":null},"genotype_count":0,"is_obsolete":false,"name":"arterial calcification of infancy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1859727","DOID:0050644","MEDGEN:395331","NORD:2001","MESH:C537440","GARD:8380","OMIMPS:208000"],"synonyms":[{"name":"Generalized Arterial Calcification of Infancy","type":"exact"},{"name":"IIAC","type":"related"},{"name":"generalised arterial calcification in infancy","type":"related"},{"name":"generalised arterial calcification of infancy","type":"exact"},{"name":"generalized arterial calcification in infancy","type":"related"},{"name":"generalized arterial calcification of infancy","type":"exact"},{"name":"idiopathic infantile arterial calcification","type":"exact"},{"name":"idiopathic obliterative arteriopathy","type":"exact"},{"name":"infantile arteriosclerosis","type":"exact"},{"name":"occlusive infantile arteriopathy","type":"exact"}],"termid":"MONDO:0018870","terms_by_termid":{"MONDO:0013768":null},"xrefs":{"Monarch":{"xref_id":"0018870"}}}


id: FYPO:0005068
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of double-strand breaks in DNA is greater than normal during S phase of the mitotic cell cycle.","definition_xrefs":["PomBase:mah","PMID:18180284"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased number of double-strand break sites during vegetative growth","termid":"FYPO:0000455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased number of double-strand break sites during mitotic S phase","synonyms":[{"name":"accumulation of DNA damage foci during mitotic S phase","type":"related"},{"name":"accumulation of double-strand break sites during mitotic S phase","type":"exact"},{"name":"increased number of DNA damage foci during mitotic S phase","type":"related"},{"name":"increased number of double-strand break sites during S phase during vegetative growth","type":"exact"},{"name":"increased number of double-strand break sites during S phase of mitotic cell cycle","type":"exact"}],"termid":"FYPO:0005068"}


id: MONDO:0011968
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive limb-girdle muscular dystrophy type 2D (LGMD2D) is a subtype of autosomal recessive limb-girdle muscular dystrophy characterized by childhood onset of progressive proximal weakness of the shoulder and pelvic girdle muscles, resulting in difficulty walking, scapular winging, calf hypertrophy and contractures of the Achilles tendon, which lead to a tiptoe gait pattern. Cardiac and respiratory involvement is rare.","definition_xrefs":["Orphanet:62"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive limb-girdle muscular dystrophy","termid":"MONDO:0015152"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of alpha-sarcoglycan","termid":"MONDO:0016141"},{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005336","MONDO:0005267"],"is_obsolete":false,"name":"autosomal recessive limb-girdle muscular dystrophy type 2D","secondary_identifiers":["MEDGEN:424706","GARD:438","NCIT:C142081","OMIM:608099","SCTID:715340002","UMLS:C2936332","DOID:0110278"],"synonyms":[{"name":"Adhalinopathy, primary","type":"related"},{"name":"Alpha-sarcoglycanopathy","type":"exact"},{"name":"DMDA2","type":"exact"},{"name":"Duchenne-like autosomal recessive muscular dystrophy type 2","type":"exact"},{"name":"Duchenne-like autosomal recessive muscular dystrophy, type 2","type":"related"},{"name":"LGMD2D","type":"exact"},{"name":"SGCA autosomal recessive limb-girdle muscular dystrophy","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy caused by mutation in SGCA","type":"exact"},{"name":"limb-girdle muscular dystrophy due to alpha-sarcoglycan deficiency","type":"exact"},{"name":"limb-girdle muscular dystrophy type 2D","type":"exact"},{"name":"limb-girdle muscular dystrophy, type 2D","type":"related"},{"name":"muscular dystrophy limb-girdle with alpha-sarcoglycan","type":"related"},{"name":"muscular dystrophy, limb-girdle, autosomal recessive 3","type":"exact"},{"name":"muscular dystrophy, limb-girdle, type 2D","type":"exact"},{"name":"primary adhalinopathy","type":"exact"}],"termid":"MONDO:0011968","xrefs":{"Monarch":{"xref_id":"0011968"}}}


id: PBO:0066906
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 207","termid":"PBO:0066906"}


id: PBO:0038795
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADAM metallopeptidase domain 1B (pseudogene)","termid":"PBO:0038795"}


id: GO:0007446
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.","definition_xrefs":["GOC:bf","GOC:jid","PMID:10679387"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental growth","termid":"GO:0048589"},{"relation_name":"part_of","term_name":"imaginal disc development","termid":"GO:0007444"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"imaginal disc growth","termid":"GO:0007446"}


id: PBO:0083038
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated","termid":"PBO:0083038"}


id: MONDO:0008020
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"multiple exostoses with spastic tetraparesis","secondary_identifiers":["MEDGEN:371889","MESH:C563566","OMIM:158345","UMLS:C1834724"],"synonyms":[{"name":"Hamann Zanki schimrigk syndrome","type":"related"},{"name":"multiple exostoses with spastic tetraparesis","type":"exact"},{"name":"spasticity multiple exostoses","type":"related"}],"termid":"MONDO:0008020","xrefs":{"Monarch":{"xref_id":"0008020"}}}


id: MONDO:0006373
data:
  {"annotated_genes":["SJAG_03429"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86693],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009050"}]},"cv_name":"mondo","definition":"A non-metastasizing tumor that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. The diagnosis can be based on imaging studies and/or radioimmunoassays. Due to its location in the sella turcica, expansion of the tumor mass can impinge on the optic chiasm or involve the temporal lobe, third ventricle and posterior fossa A frequently associated physical finding is bitemporal hemianopsia which may progress to further visual loss.","definition_xrefs":["NCIT:C3329"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"benign endocrine neoplasm","termid":"MONDO:0000627"},{"relation_name":"is_a","term_name":"adenoma","termid":"MONDO:0004972"},{"relation_name":"is_a","term_name":"pituitary tumor","termid":"MONDO:0017611"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03429":null},"genotype_count":0,"is_obsolete":false,"name":"pituitary gland adenoma","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:19680","ONCOTREE:PTAD","Orphanet:99408","EFO:1000478","MedDRA:10035079","ICD10CM:D35.2","SCTID:254956000","DOID:3829","MEDGEN:45933","UMLS:C0032000","NANDO:2200095","ICDO:8272/0"],"synonyms":[{"name":"PTAD","type":"related"},{"name":"adenoma of pituitary","type":"exact"},{"name":"adenoma of pituitary gland","type":"exact"},{"name":"adenoma of the pituitary","type":"exact"},{"name":"adenoma of the pituitary gland","type":"exact"},{"name":"adenoma, anterior lobe pituitary gland, benign","type":"exact"},{"name":"pituitary adenoma","type":"exact"},{"name":"pituitary gland adenoma","type":"exact"}],"termid":"MONDO:0006373","terms_by_termid":{"MONDO:0009050":null},"xrefs":{"Monarch":{"xref_id":"0006373"}}}


id: GO:0071085
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.","definition_xrefs":["PMID:10429193"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"alphaIIb-beta3 integrin-CD9 complex","synonyms":[{"name":"ITGA2b-ITGB3-CD9 complex","type":"narrow"}],"termid":"GO:0071085"}


id: MONDO:0700102
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm, non-human animal","termid":"MONDO:0700098"},{"relation_name":"is_a","term_name":"hematologic disorder, non-human animal","termid":"MONDO:1011319"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lymphoma, non-human animal","secondary_identifiers":["OMIA:001733"],"termid":"MONDO:0700102","xrefs":{"Monarch":{"xref_id":"0700102"}}}


id: GO:0006525
data:
  {"annotated_genes":["SJAG_03398","SJAG_00392","SJAG_00695","SJAG_00635","SJAG_00412","SJAG_00043","SJAG_00636","SJAG_01592","SJAG_04577","SJAG_01019","SJAG_01461","SJAG_00495"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[106530,111090,110479,118415,98151,111920,102626,78429,70071],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042450"},{"annotations":[78252],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019544"},{"annotations":[70336],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019547"},{"annotations":[78255,113224],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010121"},{"annotations":[70271,67334,70221,71926,65173,71099,71217,62380,57468],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006526"},{"annotations":[75544],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033387"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-amino acid metabolic process","termid":"GO:1901605"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00043":null,"SJAG_00392":null,"SJAG_00412":null,"SJAG_00495":null,"SJAG_00635":null,"SJAG_00636":null,"SJAG_00695":null,"SJAG_01019":null,"SJAG_01461":null,"SJAG_01592":null,"SJAG_03398":null,"SJAG_04577":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"arginine metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000043":null,"GO_REF:0000107":null},"secondary_identifiers":["Wikipedia:Arginine"],"synonyms":[{"name":"arginine metabolism","type":"exact"}],"termid":"GO:0006525","terms_by_termid":{"GO:0006526":null,"GO:0010121":null,"GO:0019544":null,"GO:0019547":null,"GO:0033387":null,"GO:0042450":null}}


id: PBO:0044477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 20 subfamily A member 1","termid":"PBO:0044477"}


id: PBO:0091811
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein with a role in ER insertion of tail-anchored membrane proteins","termid":"PBO:0091811"}


id: PBO:0041811
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CARHSP1 divergent transcript","termid":"PBO:0041811"}


id: MONDO:0019499
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Turner syndrome is a chromosomal disorder associated with the complete or partial absence of an X chromosome.","definition_xrefs":["Orphanet:881"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete chromosomal anomaly with cataract (obsolete MONDO:0020226)","termid":"MONDO:0020226"},{"relation_name":"is_a","term_name":"gonadal dysgenesis","termid":"MONDO:0001967"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"sex chromosome disorder of sex development","termid":"MONDO:0017975"},{"relation_name":"is_a","term_name":"inherited primary ovarian failure","termid":"MONDO:0019852"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"Turner syndrome","secondary_identifiers":["MESH:D014424","NANDO:2200410","NCIT:C26900","icd11.foundation:1987089698","SCTID:38804009","DOID:3491","UMLS:C0041408","ICD9:758.7","NORD:1806","GARD:7831","MedDRA:10045181","MEDGEN:21734"],"synonyms":[{"name":"45, X syndrome","type":"related"},{"name":"45,X gonadal dysgenesis","type":"exact"},{"name":"45,X syndrome","type":"exact"},{"name":"45,X/46,XX syndrome","type":"exact"},{"name":"45,X0 syndrome","type":"exact"},{"name":"45X syndrome","type":"exact"},{"name":"Bonnevie-Ullrich syndrome","type":"related"},{"name":"Schereshevkii Turner syndrome","type":"related"},{"name":"Turner Varny syndrome","type":"related"},{"name":"Ullrich-Turner syndrome","type":"related"},{"name":"XO syndrome","type":"exact"},{"name":"chromosome X monosomy X","type":"related"},{"name":"genital dwarfism","type":"related"},{"name":"genital dwarfism, Turner type","type":"related"},{"name":"gonadal dysgenesis","type":"broad"},{"name":"gonadal dysgenesis (45,X)","type":"related"},{"name":"gonadal dysgenesis - Turner","type":"exact"},{"name":"gonadal dysgenesis Turner type","type":"related"},{"name":"karyotype 45, X","type":"exact"},{"name":"monosomy X","type":"narrow"},{"name":"monosomy X syndrome","type":"exact"}],"termid":"MONDO:0019499","xrefs":{"Monarch":{"xref_id":"0019499"}}}


id: MONDO:0025712
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary angioedema","termid":"MONDO:0019623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"angioedema, hereditary, 4","secondary_identifiers":["MEDGEN:1787336","OMIM:619360","UMLS:C5543503"],"synonyms":[{"name":"HAE4","type":"exact"}],"termid":"MONDO:0025712","xrefs":{"Monarch":{"xref_id":"0025712"}}}


id: PBO:0041399
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C6orf47 antisense RNA 1","termid":"PBO:0041399"}


id: MONDO:0016131
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete spinal muscular atrophy associated with central nervous system anomaly (obsolete MONDO:0016131)","secondary_identifiers":["Orphanet:207012"],"termid":"MONDO:0016131","xrefs":{"Monarch":{"xref_id":"0016131"}}}


id: PBO:0018012
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"armadillo repeat protein, involved in nucleocytoplasmic transport Syo2 (predicted)","termid":"PBO:0018012"}


id: GO:0065005
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"},{"relation_name":"is_a","term_name":"protein-lipid complex organization","termid":"GO:0071825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"protein-lipid complex assembly","termid":"GO:0065005"}


id: FYPO:0005193
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of torin1 than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0005447","FYPO:0002682","FYPO:0000003","FYPO:0001985"],"is_obsolete":false,"name":"resistance to torin1","synonyms":[{"name":"resistance to torin 1","type":"exact"},{"name":"resistance to torin1 during mitotic cell cycle","type":"related"},{"name":"resistance to torin1 during vegetative growth","type":"exact"},{"name":"resistant to torin1","type":"exact"}],"termid":"FYPO:0005193"}


id: GO:1990506
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.","definition_xrefs":["PMID:16120966"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitotic DNA replication","termid":"GO:1902969"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006260"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0006259","GO:0006260","GO:0007049"],"is_obsolete":false,"name":"mitotic DNA-templated DNA replication","synonyms":[{"name":"mitotic DNA-dependent DNA replication","type":"exact"}],"termid":"GO:1990506"}


id: PBO:0060512
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NSF attachment protein gamma","termid":"PBO:0060512"}


id: GO:0032406
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a MutLbeta mismatch repair complex.","definition_xrefs":["GOC:vk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mismatch repair complex binding","termid":"GO:0032404"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"MutLbeta complex binding","termid":"GO:0032406"}


id: PBO:0109835
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TTT co-chaperone complex subunit Tti2","termid":"PBO:0109835"}


id: PBO:0086258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that regulates meiotic SPB cohesion and telomere clustering; localizes to both spindle pole bodies (SPBs) and telomeres; required for bouquet formation, effective homolog pairing, ordered cross-over distribution, sister chromatid cohesion at meiotic telomeres, chromosomal segregation and telomere-led rapid prophase movement","termid":"PBO:0086258"}


id: PBO:0080740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WWTR1 antisense RNA 1","termid":"PBO:0080740"}


id: PBO:0079468
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"twinfilin actin binding protein 1","termid":"PBO:0079468"}


id: GO:1901313
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of gene expression involved in extracellular matrix organization.","definition_xrefs":["GOC:BHF","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of gene expression involved in extracellular matrix organization (obsolete GO:1901313)","synonyms":[{"name":"activation of expression of extracellular matrix proteins","type":"exact"},{"name":"activation of extracellular matrix protein production","type":"related"},{"name":"activation of gene expression involved in extracellular matrix organization","type":"narrow"},{"name":"positive regulation of expression of extracellular matrix proteins","type":"exact"},{"name":"positive regulation of extracellular matrix protein production","type":"related"},{"name":"up regulation of expression of extracellular matrix proteins","type":"exact"},{"name":"up regulation of extracellular matrix protein production","type":"related"},{"name":"up regulation of gene expression involved in extracellular matrix organization","type":"exact"},{"name":"up-regulation of expression of extracellular matrix proteins","type":"exact"},{"name":"up-regulation of extracellular matrix protein production","type":"related"},{"name":"up-regulation of gene expression involved in extracellular matrix organization","type":"exact"},{"name":"upregulation of expression of extracellular matrix proteins","type":"exact"},{"name":"upregulation of extracellular matrix protein production","type":"related"},{"name":"upregulation of gene expression involved in extracellular matrix organization","type":"exact"}],"termid":"GO:1901313"}


id: MONDO:0044925
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma arising in the oral cavity. Most oral cavity carcinomas are squamous cell carcinomas of the tongue, buccal mucosa, or gums. Less frequent morphologic variants include mucoepidermoid carcinoma and adenocarcinoma.","definition_xrefs":["NCIT:C8990"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oral cavity cancer","termid":"MONDO:0005515"},{"relation_name":"is_a","term_name":"digestive system carcinoma","termid":"MONDO:0006181"},{"relation_name":"is_a","term_name":"lip and oral cavity carcinoma","termid":"MONDO:0023644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"oral cavity carcinoma","secondary_identifiers":["MEDGEN:57468","UMLS:C0151546"],"synonyms":[{"name":"carcinoma of mouth","type":"exact"},{"name":"carcinoma of oral cavity","type":"exact"},{"name":"carcinoma of the oral cavity","type":"exact"},{"name":"mouth carcinoma","type":"exact"},{"name":"oral cavity cancer","type":"broad"},{"name":"oral cavity carcinoma","type":"exact"}],"termid":"MONDO:0044925","xrefs":{"Monarch":{"xref_id":"0044925"}}}


id: GO:0002228
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.","definition_xrefs":["ISBN:0781735149","GOC:add","GO_REF:0000022"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lymphocyte mediated immunity","termid":"GO:0002449"},{"relation_name":"is_a","term_name":"innate immune response","termid":"GO:0045087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"natural killer cell mediated immunity","synonyms":[{"name":"NK cell mediated immunity","type":"exact"}],"termid":"GO:0002228"}


id: GO:0021832
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.","definition_xrefs":["GO_REF:0000021","GOC:dgh","GOC:jid","GOC:cls","PMID:12626695","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell adhesion via plasma-membrane adhesion molecules","termid":"GO:0098742"},{"relation_name":"part_of","term_name":"cerebral cortex tangential migration using cell-cell interactions","termid":"GO:0021823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions","termid":"GO:0021832"}


id: PBO:0075837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"somatostatin receptor 5","termid":"PBO:0075837"}


id: PBO:0060664
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nicastrin pseudogene 1","termid":"PBO:0060664"}


id: GO:0035877
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD).","definition_xrefs":["GOC:ecd","InterPro:IPR001875"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein domain specific binding","termid":"GO:0019904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"death effector domain binding","synonyms":[{"name":"DED binding","type":"exact"}],"termid":"GO:0035877"}


id: PATO:0001268
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of brown hue and low saturation.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brown","termid":"PATO:0000952"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"desaturated brown","synonyms":[{"name":"pale brown","type":"exact"}],"termid":"PATO:0001268"}


id: PBO:0056413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"membrane associated ring-CH-type finger 10","termid":"PBO:0056413"}


id: MONDO:0022849
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital stenosis of cervical medullary canal","termid":"MONDO:0022849","xrefs":{"Monarch":{"xref_id":"0022849"}}}


id: GO:0047420
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid.","definition_xrefs":["EC:3.5.1.81","MetaCyc:3.5.1.81-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016810","GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"N-acyl-D-amino-acid deacylase activity","secondary_identifiers":["RHEA:18309"],"synonyms":[{"name":"D-aminoacylase activity","type":"related"},{"name":"N-acyl-D-amino acid amidohydrolase activity","type":"related"}],"termid":"GO:0047420"}


id: PBO:0059627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MTCH1 pseudogene 2","termid":"PBO:0059627"}


id: PBO:0114134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulfite transmembrane transporter Ssu1","termid":"PBO:0114134"}


id: PBO:0050490
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homeobox B cluster","termid":"PBO:0050490"}


id: PBO:0045661
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DPY30 domain containing 1","termid":"PBO:0045661"}


id: PBO:0081156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein, FOG family member 1","termid":"PBO:0081156"}


id: PBO:0086706
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; mCherry fusion protein localizes to the cytosol and nucleus","termid":"PBO:0086706"}


id: PBO:0028598
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_hydrostatic_pressure","termid":"PBO:0028598"}


id: FYPO:0003133
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is too low to detect.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide absent from cell","termid":"FYPO:0001209"},{"relation_name":"is_a","term_name":"decreased cell wall galactomannan level","termid":"FYPO:0002265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002946"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002946","FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"galactomannan absent from cell wall","synonyms":[{"name":"galactomannan absent from cell surface","type":"related"},{"name":"galactomannan absent from cell wall during mitotic cell cycle","type":"related"},{"name":"galactomannan absent from cell wall during vegetative growth","type":"exact"}],"termid":"FYPO:0003133"}


id: PBO:0089977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein phosphatase PP1 catalytic subunit Dis2","termid":"PBO:0089977"}


id: PBO:0079850
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unc-80 homolog, NALCN channel complex subunit","termid":"PBO:0079850"}


id: PBO:0083746
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential component of the TIM23 complex; acts as receptor for the translocase of the inner mitochondrial membrane (TIM23) complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel","termid":"PBO:0083746"}


id: PBO:0074610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 14B","termid":"PBO:0074610"}


id: PBO:0109284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"xylitol dehydrogenase","termid":"PBO:0109284"}


id: FYPO:0001384
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which a protein kinase activity is absent.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished catalytic activity","termid":"FYPO:0000664"},{"relation_name":"is_a","term_name":"abnormal protein kinase activity","termid":"FYPO:0001381"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000654","FYPO:0000661","FYPO:0000707","FYPO:0001985"],"is_obsolete":false,"name":"abolished protein kinase activity","synonyms":[{"name":"protein kinase activity abolished","type":"exact"}],"termid":"FYPO:0001384"}


id: MONDO:0009081
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hypopigmentation of the skin","termid":"MONDO:0019290"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"deafness, congenital, with total albinism","secondary_identifiers":["MESH:C565646","UMLS:C1857343","OMIM:220900","MEDGEN:387799"],"synonyms":[{"name":"deafness, congenital, with total albinism","type":"exact"}],"termid":"MONDO:0009081","xrefs":{"Monarch":{"xref_id":"0009081"}}}


id: PBO:0070744
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L10 like","termid":"PBO:0070744"}


id: PBO:0058274
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4651","termid":"PBO:0058274"}


id: GO:0170045
data:
  {"annotated_genes":["SJAG_04984"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[100242],"is_not":false,"summary":null,"term":"GO:0170045"}]},"cv_name":"molecular_function","definition":"Enables the transfer of isopentenyl pyrophosphate from one side of a membrane to the other.","definition_xrefs":["PMID:37813972","GOC:ew"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid transporter activity","termid":"GO:0005548"},{"relation_name":"is_a","term_name":"organic anion transmembrane transporter activity","termid":"GO:0008514"},{"relation_name":"is_a","term_name":"organophosphate ester transmembrane transporter activity","termid":"GO:0015605"},{"relation_name":"is_a","term_name":"lipid transmembrane transporter activity","termid":"GO:0170055"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04984":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"isopentenyl pyrophosphate transmembrate transporter activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"IPP transmembrane transport activity","type":"exact"},{"name":"isopentenyl diphosphate transmembrane transport activity","type":"exact"}],"termid":"GO:0170045","terms_by_termid":{"GO:0170045":null}}


id: MONDO:0017386
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive malignant mesenchymal neoplasm with skeletal muscle differentiation, occurring in adults and rarely in children. The tumor is characterized by the presence of bizarre round, spindle, and polygonal cells. Clinical presentation includes a rapidly enlarging painful mass usually of the lower extremities.","definition_xrefs":["NCIT:C4258"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rhabdomyosarcoma","termid":"MONDO:0005212"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"pleomorphic rhabdomyosarcoma","secondary_identifiers":["MEDGEN:137770","SCTID:404054005","Orphanet:293199","UMLS:C0334480","ONCOTREE:PLRMS","DOID:3250","ICD9:171.9","GARD:21165"],"synonyms":[{"name":"anaplastic rhabdomyosarcoma","type":"exact"},{"name":"pleomorphic rhabdomyosarcoma","type":"exact"},{"name":"pleomorphic rhabdomyosarcoma, adult type","type":"exact"}],"termid":"MONDO:0017386","xrefs":{"Monarch":{"xref_id":"0017386"}}}


id: FYPO:0007499
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more cohesin-associated regions (CARs) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin.","definition_xrefs":["PMID:27226485","PomBase:mah","PMID:31895039"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased chromatin binding","termid":"FYPO:0002980"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000702"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0001985","FYPO:0000702","FYPO:0000707"],"is_obsolete":false,"name":"increased chromatin binding at cohesin associated regions","synonyms":[{"name":"increased chromatin binding at CARs","type":"exact"},{"name":"increased chromatin binding at cohesin associated regions during mitotic cell cycle","type":"related"},{"name":"increased chromatin binding at cohesin associated regions during vegetative growth","type":"exact"}],"termid":"FYPO:0007499"}


id: GO:0002020
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a protease or a peptidase.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme binding","termid":"GO:0019899"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"protease binding","secondary_identifiers":["Reactome:R-HSA-1297354"],"termid":"GO:0002020"}


id: MONDO:1010001
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Epilepsy that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epilepsy, non-human animal","secondary_identifiers":["OMIA:000344"],"termid":"MONDO:1010001","xrefs":{"Monarch":{"xref_id":"1010001"}}}


id: PBO:0056139
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine zipper tumor suppressor 1","termid":"PBO:0056139"}


id: PBO:0090492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane anchored protein, claudin family, predicted membrane sensor Mac1","termid":"PBO:0090492"}


id: PBO:0046276
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EMG1 N1-specific pseudouridine methyltransferase","termid":"PBO:0046276"}


id: PBO:0039928
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho guanine nucleotide exchange factor 33","termid":"PBO:0039928"}


id: PBO:0060544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAV2 antisense RNA 4","termid":"PBO:0060544"}


id: GO:0034487
data:
  {"annotated_genes":["SJAG_00051"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90356],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034488"}]},"cv_name":"biological_process","definition":"The process in which an amino acid is transported from one side of the vacuolar membrane to the other.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid transmembrane transport","termid":"GO:0003333"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00051":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"vacuolar amino acid transmembrane transport","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"vacuolar amino acid membrane transport","type":"exact"}],"termid":"GO:0034487","terms_by_termid":{"GO:0034488":null}}


id: GO:0102654
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]. The this activity introduces an unusual trans double bond at carbon 3 of a palmitoyl group attached to the sn-2 position of glycerolipids.","definition_xrefs":["RHEA:46764"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water","termid":"GO:0016717"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"palmitoyl-[glycerolipid] 3-(E)-desaturase activity","secondary_identifiers":["EC:1.14.19.43","MetaCyc:RXN-16053"],"synonyms":[{"name":"1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity","type":"related"}],"termid":"GO:0102654"}


id: PBO:0059670
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 36","termid":"PBO:0059670"}


id: PATO:0000674
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000674 absolute temperature value (obsolete PATO:0000674)","termid":"PATO:0000674"}


id: MONDO:0003221
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete sclerosing hemangioma (obsolete MONDO:0003221)","termid":"MONDO:0003221","xrefs":{"Monarch":{"xref_id":"0003221"}}}


id: GO:0097317
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus.","definition_xrefs":["PMID:18679170","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"filamentous growth of a population of unicellular organisms in response to biotic stimulus","termid":"GO:0036180"},{"relation_name":"is_a","term_name":"invasive filamentous growth","termid":"GO:0036267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"invasive growth in response to biotic stimulus","termid":"GO:0097317"}


id: GO:0032466
data:
  {"annotated_genes":["SJAG_03508","SJAG_00845","SJAG_02514","SJAG_02169","SJAG_03048","SJAG_01464","SJAG_06270","SJAG_04551","SJAG_03353","SJAG_03592","SJAG_04943","SJAG_01790","SJAG_00526","SJAG_00883","SJAG_00229","SJAG_03681","SJAG_01386","SJAG_02795","SJAG_04455"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[98271],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000432"},{"annotations":[102370],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903500"},{"annotations":[103699],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903472"},{"annotations":[92810,107111,99668,102148],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902413"},{"annotations":[102375],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905757"},{"annotations":[92895,92811,110185,107112,101278,72680,95613,99591,115929,90690,107555,93429,107248,105052,91699],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031030"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell cycle process","termid":"GO:0010948"},{"relation_name":"is_a","term_name":"regulation of cytokinesis","termid":"GO:0032465"},{"relation_name":"is_a","term_name":"negative regulation of cell division","termid":"GO:0051782"},{"relation_name":"negatively_regulates","term_name":"cytokinesis","termid":"GO:0000910"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00229":null,"SJAG_00526":null,"SJAG_00845":null,"SJAG_00883":null,"SJAG_01386":null,"SJAG_01464":null,"SJAG_01790":null,"SJAG_02169":null,"SJAG_02514":null,"SJAG_02795":null,"SJAG_03048":null,"SJAG_03353":null,"SJAG_03508":null,"SJAG_03592":null,"SJAG_03681":null,"SJAG_04455":null,"SJAG_04551":null,"SJAG_04943":null,"SJAG_06270":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"negatively_regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"negative regulation of cytokinesis","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0071776"],"synonyms":[{"name":"down regulation of cytokinesis","type":"exact"},{"name":"down-regulation of cytokinesis","type":"exact"},{"name":"downregulation of cytokinesis","type":"exact"},{"name":"inhibition of cytokinesis","type":"narrow"},{"name":"negative regulation of cell cycle cytokinesis","type":"related"}],"termid":"GO:0032466","terms_by_termid":{"GO:0031030":null,"GO:1902413":null,"GO:1903472":null,"GO:1903500":null,"GO:1905757":null,"GO:2000432":null}}


id: PBO:0031487
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_meiotic_spindle","termid":"PBO:0031487"}


id: GO:0004089
data:
  {"annotated_genes":["SJAG_06611"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[77549],"is_not":false,"summary":null,"term":"GO:0004089"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: hydrogencarbonate + H+ = CO2 + H2O.","definition_xrefs":["EC:4.2.1.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":1,"genes_by_uniquename":{"SJAG_06611":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"carbonate dehydratase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-1237045","Reactome:R-HSA-1475436","Reactome:R-HSA-1237059","MetaCyc:RXN0-5224","Reactome:R-HSA-1237047","Reactome:R-HSA-1475025","Reactome:R-HSA-1475435","Reactome:R-HSA-1475026","RHEA:10748","Reactome:R-HSA-1475022","Reactome:R-HSA-1475028","Reactome:R-HSA-1237081","Reactome:R-HSA-1475017","Reactome:R-HSA-1475032"],"synonyms":[{"name":"anhydrase activity","type":"related"},{"name":"carbonate anhydrase activity","type":"related"},{"name":"carbonate hydro-lyase (carbon-dioxide-forming)","type":"related"},{"name":"carbonate hydro-lyase activity","type":"related"},{"name":"carbonic acid anhydrase activity","type":"related"},{"name":"carbonic anhydrase A","type":"related"},{"name":"carbonic anhydrase activity","type":"exact"},{"name":"carbonic dehydratase activity","type":"related"},{"name":"carboxyanhydrase activity","type":"related"}],"termid":"GO:0004089","terms_by_termid":{"GO:0004089":null}}


id: PBO:0078890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gln (anticodon CTG) 3-1","termid":"PBO:0078890"}


id: PBO:0047829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FOXP1 divergent transcript","termid":"PBO:0047829"}


id: PBO:0030547
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_valine_import","termid":"PBO:0030547"}


id: PBO:0060495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleosome assembly protein 1 like 1","termid":"PBO:0060495"}


id: MONDO:0019691
data:
  {"annotated_genes":["SJAG_01370"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86782],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054565"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01370":null},"genotype_count":0,"is_obsolete":false,"name":"short rib dysplasia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:756.3","UMLS:C0432195","GARD:16822","SCTID:254050009","MEDGEN:609403","Orphanet:93426"],"synonyms":[{"name":"SRP","type":"exact"},{"name":"ciliopathies with major skeletal involvement","type":"related"},{"name":"short-rib dysplasia (with or without polydactyly)","type":"exact"}],"termid":"MONDO:0019691","terms_by_termid":{"MONDO:0054565":null},"xrefs":{"Monarch":{"xref_id":"0019691"}}}


id: PBO:0049859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2","termid":"PBO:0049859"}


id: GO:0009626
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The rapid, localized death of plant cells in response to invasion by a pathogen.","definition_xrefs":["ISBN:0582227089"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to stress","termid":"GO:0033554"},{"relation_name":"is_a","term_name":"symbiont-induced defense-related programmed cell death","termid":"GO:0034050"},{"relation_name":"is_a","term_name":"innate immune response","termid":"GO:0045087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"plant-type hypersensitive response","synonyms":[{"name":"HR","type":"broad"},{"name":"HR-PCD","type":"exact"},{"name":"plant hypersensitive response","type":"exact"}],"termid":"GO:0009626"}


id: MONDO:0009168
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fowler syndrome","secondary_identifiers":["GARD:17138","MESH:C565593","Orphanet:221126","MEDGEN:384026","OMIM:225790","SCTID:700242002","DOID:0111666","UMLS:C1856972","MedDRA:10071718","ICD9:596.59"],"synonyms":[{"name":"Encephaloclastic proliferative vasculopathy","type":"exact"},{"name":"Fowler syndrome","type":"exact"},{"name":"PVHH","type":"related"},{"name":"cerebral proliferative glomeruloid vasculopathy","type":"exact"},{"name":"hydranencephaly, fowler type","type":"related"},{"name":"hydrocephaly/hydranencephaly due to cerebral vasculopathy","type":"exact"},{"name":"proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome","type":"related"},{"name":"proliferative vasculopathy and hydranencephaly/hydrocephaly","type":"exact"}],"termid":"MONDO:0009168","xrefs":{"Monarch":{"xref_id":"0009168"}}}


id: GO:0042462
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.","definition_xrefs":["ISBN:0192800981","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"photoreceptor cell development","termid":"GO:0042461"},{"relation_name":"part_of","term_name":"eye photoreceptor cell differentiation","termid":"GO:0001754"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"eye photoreceptor cell development","termid":"GO:0042462"}


id: PBO:0017068
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces pombe specific protein Meu15","termid":"PBO:0017068"}


id: MOD:00778
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"Natural or modified residues with a mass of 182.9-183.0 Da.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"residues isobaric at a resolution below 0.1 Da","termid":"MOD:00616"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"residues isobaric at 182.9-183.0 Da","termid":"MOD:00778"}


id: PBO:0082889
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation","termid":"PBO:0082889"}


id: PBO:0013841
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"primary microcephaly","termid":"PBO:0013841"}


id: FYPO:0007015
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the 3' ends of tRNA genes is increased.","definition_xrefs":["PMID:31294478","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein localization to chromatin at tRNA genes","termid":"FYPO:0004033"},{"relation_name":"is_a","term_name":"increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes","termid":"FYPO:0007734"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0001320","FYPO:0000138"],"is_obsolete":false,"name":"increased protein localization to chromatin at 3' end of tRNA genes","synonyms":[{"name":"increased protein localisation to chromatin at 3' end of tRNA genes","type":"exact"},{"name":"increased protein localization to chromatin at 3' end of tRNA genes during mitotic cell cycle","type":"related"},{"name":"increased protein localization to chromatin at 3' end of tRNA genes during vegetative growth","type":"exact"},{"name":"increased protein localization to chromatin at 3' end of transfer RNA genes","type":"exact"},{"name":"increased protein localization to chromatin at tRNA genes at 3' end","type":"exact"}],"termid":"FYPO:0007015"}


id: PBO:0042855
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cilia and flagella associated protein 69","termid":"PBO:0042855"}


id: PBO:0057319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 518f","termid":"PBO:0057319"}


id: MONDO:0004908
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete galactosemia (obsolete MONDO:0004908)","termid":"MONDO:0004908","xrefs":{"Monarch":{"xref_id":"0004908"}}}


id: MONDO:0020547
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chronic graft versus host disease (GVHD) is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted donor cells attack the transplant recipient's body. Symptoms may include skin rash, mouth sores, dry eyes, liver inflammation, development of scar tissue in the skin and joints, and damage to the lungs. The exact cause of chronic GVHD is unknown.It likely results from a complex immune-mediated interaction between the donor and recipient cells.Chronic GVHD is treated with prednisone or other similar anti-inflammatory or immunosuppressive medications.","direct_ancestors":[{"relation_name":"is_a","term_name":"graft versus host disease","termid":"MONDO:0013730"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"chronic graft versus host disease","secondary_identifiers":["icd11.foundation:621183043","GARD:10964","MEDGEN:167851","NANDO:2100213","NCIT:C4981","Orphanet:99921","NANDO:2200812","UMLS:C0867389","SCTID:402356004","ICD9:279.52","ICD10CM:D89.811","MedDRA:10066261"],"synonyms":[{"name":"GVHD, chronic","type":"exact"},{"name":"chronic GVHD","type":"related"},{"name":"graft versus host disease, chronic","type":"exact"}],"termid":"MONDO:0020547","xrefs":{"Monarch":{"xref_id":"0020547"}}}


id: PBO:0070344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY4 pseudogene 17","termid":"PBO:0070344"}


id: PBO:0051686
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inka box actin regulator 2","termid":"PBO:0051686"}


id: GO:0051032
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleobase-containing compound transmembrane transporter activity","termid":"GO:0015932"},{"relation_name":"is_a","term_name":"macromolecule transmembrane transporter activity","termid":"GO:0022884"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"nucleic acid transmembrane transporter activity","termid":"GO:0051032"}


id: PBO:0072529
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein SA pseudogene 59","termid":"PBO:0072529"}


id: FYECO:0000165
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which sodium sulfide (Na2S) was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ Na2S","synonyms":[{"name":"sodium sulfide added","type":"exact"}],"termid":"FYECO:0000165"}


id: PBO:0067481
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 615, pseudogene","termid":"PBO:0067481"}


id: PBO:0054732
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2141","termid":"PBO:0054732"}


id: MONDO:1011074
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Urolithiasis that occurs in Dusky leaf-monkey.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urolithiasis, non-human animal","termid":"MONDO:1010267"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"urolithiasis, Dusky leaf-monkey","secondary_identifiers":["OMIA:001033-54181"],"termid":"MONDO:1011074","xrefs":{"Monarch":{"xref_id":"1011074"}}}


id: SO:0002063
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An insertion of sequence from the Alu family of mobile elements.","definition_xrefs":["NCBI:th"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mobile_element_insertion","termid":"SO:0001837"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alu_insertion","synonyms":[{"name":"Alu insertion","type":"exact"}],"termid":"SO:0002063"}


id: MONDO:0022770
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"circumscribed cutaneous aplasia of the vertex","termid":"MONDO:0022770","xrefs":{"Monarch":{"xref_id":"0022770"}}}


id: PBO:0003153
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oligosaccharyltransferase subunit Stt3","termid":"PBO:0003153"}


id: FYPO:0007110
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which cells contain fewer microtubule bundles associated with the spindle pole body than normal during meiosis I.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule bundles present in decreased numbers","termid":"FYPO:0002818"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002399"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"output_of","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0002399","FYPO:0001985","FYPO:0005447","FYPO:0000054","FYPO:0000002"],"is_obsolete":false,"name":"microtubule bundles present in decreased numbers at spindle pole body during meiosis I","synonyms":[{"name":"decreased level of MT bundles at spindle pole body during meiosis I","type":"exact"},{"name":"decreased number of microtubule bundles at spindle pole body during meiosis I","type":"exact"},{"name":"meiosis I SPB microtubule bundles present in decreased numbers","type":"exact"},{"name":"microtubule bundles present in decreased numbers at SPB during meiosis I","type":"exact"},{"name":"microtubule bundles present in lower numbers at spindle pole body during meiosis I","type":"exact"},{"name":"microtubule bundles present in reduced numbers at spindle pole body during meiosis I","type":"exact"}],"termid":"FYPO:0007110"}


id: PBO:0003698
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HRD ubiquitin ligase complex subunit (predicted)","termid":"PBO:0003698"}


id: GO:1902292
data:
  {"annotated_genes":["SJAG_02667","SJAG_05239","SJAG_04341","SJAG_01210","SJAG_03451","SJAG_00399","SJAG_02607","SJAG_00874","SJAG_03438","SJAG_02348","SJAG_02172","SJAG_02074","SJAG_00364","SJAG_01823","SJAG_03160","SJAG_02908","SJAG_03695","SJAG_00857","SJAG_02162","SJAG_01354","SJAG_03048","SJAG_03720","SJAG_04879","SJAG_01762","SJAG_00884","SJAG_04671","SJAG_00536","SJAG_04995","SJAG_04210"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[113583,109955,115429,107361],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0140529"},{"annotations":[103323],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0140530"},{"annotations":[74813,107364,111402,115433,79208,99359,91929,113176,99422,73183,94521,70798,107259,110574,74538,106440,117365],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902975"},{"annotations":[97761,102372,108909],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1903467"},{"annotations":[102959],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902315"},{"annotations":[117304,103326,112053],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1903468"},{"annotations":[106634,89015,102378,116259],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1904514"}]},"cv_name":"biological_process","definition":"Any DNA replication initiation that is involved in cell cycle DNA replication.","definition_xrefs":["GOC:TermGenie","GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA replication initiation","termid":"GO:0006270"},{"relation_name":"is_a","term_name":"cell cycle process","termid":"GO:0022402"},{"relation_name":"part_of","term_name":"cell cycle DNA replication","termid":"GO:0044786"}],"gene_count":29,"genes_by_uniquename":{"SJAG_00364":null,"SJAG_00399":null,"SJAG_00536":null,"SJAG_00857":null,"SJAG_00874":null,"SJAG_00884":null,"SJAG_01210":null,"SJAG_01354":null,"SJAG_01762":null,"SJAG_01823":null,"SJAG_02074":null,"SJAG_02162":null,"SJAG_02172":null,"SJAG_02348":null,"SJAG_02607":null,"SJAG_02667":null,"SJAG_02908":null,"SJAG_03048":null,"SJAG_03160":null,"SJAG_03438":null,"SJAG_03451":null,"SJAG_03695":null,"SJAG_03720":null,"SJAG_04210":null,"SJAG_04341":null,"SJAG_04671":null,"SJAG_04879":null,"SJAG_04995":null,"SJAG_05239":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006260"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006260","GO:0007049","GO:0006259"],"is_obsolete":false,"name":"cell cycle DNA replication initiation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"DNA endoreduplication initiation involved in cell cycle DNA replication","type":"narrow"},{"name":"DNA re-replication initiation involved in cell cycle DNA replication","type":"narrow"},{"name":"DNA replication initiation involved in cell cycle DNA replication","type":"exact"},{"name":"DNA-dependent DNA replication initiation involved in cell cycle DNA replication","type":"exact"}],"termid":"GO:1902292","terms_by_termid":{"GO:0140529":null,"GO:0140530":null,"GO:1902315":null,"GO:1902975":null,"GO:1903467":null,"GO:1903468":null,"GO:1904514":null}}


id: PBO:0040873
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bone morphogenetic protein 1","termid":"PBO:0040873"}


id: PBO:0088562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"short chain dehydrogenase DHRS3 family, implicated in lipid (isoprenoid) metabolism","termid":"PBO:0088562"}


id: PBO:0050217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosome binding domain 1 pseudogene 34","termid":"PBO:0050217"}


id: GO:0061011
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.","definition_xrefs":["GOC:dph","PMID:20614624"],"direct_ancestors":[{"relation_name":"is_a","term_name":"common bile duct development","termid":"GO:0061009"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hepatic duct development","termid":"GO:0061011"}


id: FYPO:0004609
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which cells contain more spindle pole bodies (SPBs) than normal during one or both meiotic nuclear divisions. In this phenotype, extra SPBs typically contain normal components but seldom attach to spindle microtubules.","definition_xrefs":["PMID:15569158","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal subcellular component","termid":"FYPO:0000287"},{"relation_name":"output_of","term_name":"increased meiotic spindle pole body duplication","termid":"FYPO:0007259"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0000631","FYPO:0000054"],"is_obsolete":false,"name":"spindle pole bodies present in increased numbers during meiosis","synonyms":[{"name":"SPBs present in increased numbers during meiosis","type":"exact"},{"name":"excess meiotic spindle pole bodies present","type":"exact"},{"name":"excess spindle pole bodies present during meiosis","type":"exact"},{"name":"extra spindle pole bodies present during meiosis","type":"exact"},{"name":"pseudo-SPBs present during meiosis","type":"exact"},{"name":"spindle pole bodies present in greater numbers during meiosis","type":"exact"},{"name":"spindle pole bodies present in increased numbers during meiotic nuclear division","type":"exact"}],"termid":"FYPO:0004609"}


id: GO:0002141
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia.","definition_xrefs":["PMID:17567809"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stereocilia coupling link","termid":"GO:0002139"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"stereocilia ankle link","termid":"GO:0002141"}


id: PBO:0116711
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 56 subfamily B member 2","termid":"PBO:0116711"}


id: GO:0035347
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of nucleobase-containing compound transport","termid":"GO:0032240"},{"relation_name":"is_a","term_name":"regulation of hypoxanthine transport","termid":"GO:0035345"},{"relation_name":"negatively_regulates","term_name":"hypoxanthine transport","termid":"GO:0035344"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of hypoxanthine transport","synonyms":[{"name":"negative regulation of 6-hydroxypurine transport","type":"exact"}],"termid":"GO:0035347"}


id: PBO:0003032
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cysteine transporter (predicted)","termid":"PBO:0003032"}


id: GO:0030377
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the urokinase plasminogen activator to initiate a change in cell activity.","definition_xrefs":["GOC:mah","PMID:16456079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signaling receptor activity","termid":"GO:0038023"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"urokinase plasminogen activator receptor activity","secondary_identifiers":["Wikipedia:Urokinase_receptor"],"synonyms":[{"name":"U-plasminogen activator receptor activity","type":"exact"},{"name":"uPAR","type":"exact"},{"name":"urokinase plasminogen activator receptor","type":"exact"}],"termid":"GO:0030377"}


id: GO:0120060
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.","definition_xrefs":["GOC:sl","PMID:15890336"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of gastric motility","termid":"GO:1905333"},{"relation_name":"regulates","term_name":"gastric emptying","termid":"GO:0035483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of gastric emptying","synonyms":[{"name":"regulation of small bowel emptying","type":"exact"},{"name":"regulation of small intestine emptying","type":"exact"}],"termid":"GO:0120060"}


id: PBO:0082191
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Aldehyde reductase; reduces aliphatic aldehyde substrates using NADH as cofactor; shown to reduce carbonyl compounds to chiral alcohols","termid":"PBO:0082191"}


id: GO:2000231
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of fibroblast proliferation","termid":"GO:0048146"},{"relation_name":"is_a","term_name":"regulation of pancreatic stellate cell proliferation","termid":"GO:2000229"},{"relation_name":"positively_regulates","term_name":"pancreatic stellate cell proliferation","termid":"GO:0072343"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of pancreatic stellate cell proliferation","termid":"GO:2000231"}


id: MOD:00553
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a (2-sulfanylethyl)sulfanyl (or thioethylthiol) group for a hydroxy group.","definition_xrefs":["DeltaMass:0","PubMed:11507762","Unimod:200"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1,2-ethanedithiol modified residue","synonyms":[{"name":"1,2-ethanedithiol (EDT)","type":"exact"},{"name":"EDT","type":"related"},{"name":"Ethanedithiol","type":"related"}],"termid":"MOD:00553"}


id: PBO:0068121
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 428","termid":"PBO:0068121"}


id: PATO:0000721
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000721 absolute yield value (obsolete PATO:0000721)","termid":"PATO:0000721"}


id: FYPO:0005457
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell during a cellular response to osmotic stress is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased cellular glycerol level","termid":"FYPO:0002812"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"decreased cellular glycerol level during cellular response to osmotic stress","synonyms":[{"name":"decreased cellular glycerol level during cellular response to osmotic stress during mitotic cell cycle","type":"related"},{"name":"decreased cellular glycerol level during cellular response to osmotic stress during vegetative growth","type":"exact"},{"name":"decreased glycerol accumulation during cellular response to osmotic stress","type":"related"},{"name":"reduced cellular glycerol level during cellular response to osmotic stress","type":"exact"}],"termid":"FYPO:0005457"}


id: GO:0106201
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a diphosphate.","definition_xrefs":["GOC:hjd"],"gene_count":0,"genotype_count":0,"name":"obsolete translocase activity acting on amino acids and peptides linked to the hydrolysis of a diphosphate (obsolete GO:0106201)","termid":"GO:0106201"}


id: PBO:0054446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1843","termid":"PBO:0054446"}


id: PR:O14030
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- clr5 gene.","definition_xrefs":["UniProtKB:O14030","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C29B12.08 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC29B12.08","synonyms":[{"name":"Spom972h-clr5","type":"exact"}],"termid":"PR:O14030"}


id: GO:0035531
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).","definition_xrefs":["GOC:bf","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of chemokine production","termid":"GO:0032642"},{"relation_name":"regulates","term_name":"chemokine (C-C motif) ligand 6 production","termid":"GO:0035530"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of chemokine (C-C motif) ligand 6 production","secondary_identifiers":["GO:0035535","GO:0035534"],"synonyms":[{"name":"chemokine (C-C motif) ligand 6 secretion","type":"narrow"},{"name":"regulation of CCL6 production","type":"exact"},{"name":"regulation of chemokine (C-C motif) ligand 6 secretion","type":"narrow"}],"termid":"GO:0035531"}


id: PR:Q9UT16
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ATP synthase mitochondrial F1 complex assembly factor 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00598","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein atp12, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC9.12c","secondary_identifiers":["UniProtKB:Q9UT16"],"synonyms":[{"name":"Spom972h-ATPAF2","type":"exact"}],"termid":"PR:Q9UT16"}


id: MONDO:0000026
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Fanconi renotubular syndrome (obsolete MONDO:0000026)","termid":"MONDO:0000026","xrefs":{"Monarch":{"xref_id":"0000026"}}}


id: GO:0002712
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of B cell mediated immunity.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lymphocyte mediated immunity","termid":"GO:0002706"},{"relation_name":"is_a","term_name":"regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","termid":"GO:0002822"},{"relation_name":"regulates","term_name":"B cell mediated immunity","termid":"GO:0019724"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of B cell mediated immunity","synonyms":[{"name":"regulation of B lymphocyte mediated immunity","type":"exact"},{"name":"regulation of B-cell mediated immunity","type":"exact"},{"name":"regulation of B-lymphocyte mediated immunity","type":"exact"}],"termid":"GO:0002712"}


id: PBO:0042371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD200 molecule","termid":"PBO:0042371"}


id: GO:0005618
data:
  {"annotated_genes":["SJAG_01028","SJAG_02916","SJAG_01835","SJAG_01755","SJAG_06622","SJAG_03483","SJAG_04327","SJAG_03013","SJAG_04073","SJAG_00027","SJAG_03824","SJAG_04067","SJAG_01290","SJAG_00876","SJAG_00340","SJAG_02649","SJAG_01288","SJAG_02192","SJAG_04864","SJAG_04771","SJAG_03204","SJAG_05285","SJAG_00096","SJAG_04720","SJAG_02945","SJAG_01017","SJAG_04238","SJAG_03828","SJAG_01086","SJAG_02131","SJAG_06621","SJAG_01970","SJAG_01975","SJAG_02222","SJAG_03295","SJAG_02478","SJAG_00239","SJAG_00218","SJAG_02093","SJAG_00620","SJAG_02135","SJAG_00784","SJAG_03057","SJAG_04236","SJAG_04723","SJAG_03903","SJAG_04184","SJAG_01321"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[117817,114099,90204,114387,109084],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005619"},{"annotations":[107786],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0043188"},{"annotations":[91734],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0005631"},{"annotations":[88645],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010339"},{"annotations":[102723,106870,102974,102973,116589],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0070263"},{"annotations":[90078,101515,72392,108930,113356,108928,108931,75705,93985,108932,115649,117809,118366,76255,89880,113355,114778,74396,71118,108926,115626,106705,114497,91558,108927,77787,73279,73141,102455,108929,106114,76613],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009277"},{"annotations":[87469],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0005632"},{"annotations":[87573,87574,115844],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031160"}]},"cv_name":"cellular_component","definition":"The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.","definition_xrefs":["Wikipedia:Microbial_cyst","PMID:15134259","ISBN:0198547684","GOC:giardia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"external encapsulating structure","termid":"GO:0030312"}],"gene_count":48,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00096":null,"SJAG_00218":null,"SJAG_00239":null,"SJAG_00340":null,"SJAG_00620":null,"SJAG_00784":null,"SJAG_00876":null,"SJAG_01017":null,"SJAG_01028":null,"SJAG_01086":null,"SJAG_01288":null,"SJAG_01290":null,"SJAG_01321":null,"SJAG_01755":null,"SJAG_01835":null,"SJAG_01970":null,"SJAG_01975":null,"SJAG_02093":null,"SJAG_02131":null,"SJAG_02135":null,"SJAG_02192":null,"SJAG_02222":null,"SJAG_02478":null,"SJAG_02649":null,"SJAG_02916":null,"SJAG_02945":null,"SJAG_03013":null,"SJAG_03057":null,"SJAG_03204":null,"SJAG_03295":null,"SJAG_03483":null,"SJAG_03824":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04067":null,"SJAG_04073":null,"SJAG_04184":null,"SJAG_04236":null,"SJAG_04238":null,"SJAG_04327":null,"SJAG_04720":null,"SJAG_04723":null,"SJAG_04771":null,"SJAG_04864":null,"SJAG_05285":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"in_subsets":["cc_goslim_japonicus"],"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"cell wall","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Wikipedia:Cell_wall"],"termid":"GO:0005618","terms_by_termid":{"GO:0005619":null,"GO:0005631":null,"GO:0005632":null,"GO:0009277":null,"GO:0010339":null,"GO:0031160":null,"GO:0043188":null,"GO:0070263":null}}


id: PBO:0039935
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho guanine nucleotide exchange factor 39","termid":"PBO:0039935"}


id: MONDO:0012258
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A basal subtype of epidermolysis bullosa simplex (EBS) characterized by belt-like areas of erythema with multiple vesicles and small blisters at the advancing edge of erythema.","definition_xrefs":["Orphanet:158681"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epidermolysis bullosa simplex","termid":"MONDO:0017610"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"epidermolysis bullosa simplex 2E, with migratory circinate erythema","secondary_identifiers":["OMIM:609352","GARD:16990","MEDGEN:324475","MESH:C563730","SCTID:716700003","UMLS:C1836284"],"synonyms":[{"name":"EBS-migr","type":"exact"},{"name":"epidermolysis bullosa simplex 2E, with migratory circinate erythema","type":"exact"},{"name":"epidermolysis bullosa simplex with migratory circinate erythema","type":"exact"}],"termid":"MONDO:0012258","xrefs":{"Monarch":{"xref_id":"0012258"}}}


id: GO:0106019
data:
  {"annotated_genes":["SJAG_04545","SJAG_00063","SJAG_03375"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74916,75431,73712],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004439"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylinositol bisphosphate phosphatase activity","termid":"GO:0034593"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00063":null,"SJAG_03375":null,"SJAG_04545":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787","GO:0016788"],"is_obsolete":false,"name":"phosphatidylinositol-4,5-bisphosphate phosphatase activity","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0106019","terms_by_termid":{"GO:0004439":null}}


id: PBO:0004029
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleoporin Nup44","termid":"PBO:0004029"}


id: GO:0071620
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans).","definition_xrefs":["PMID:17079683","GOC:krc"],"gene_count":0,"genotype_count":0,"name":"obsolete phosphorylation of RNA polymerase II C-terminal domain serine 5 residues (obsolete GO:0071620)","termid":"GO:0071620"}


id: MONDO:0018117
data:
  {"annotated_genes":["SJAG_01356","SJAG_02305","SJAG_04178","SJAG_04110","SJAG_02885","SJAG_00404","SJAG_04323","SJAG_01918","SJAG_02119"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86604,86605],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013760"},{"annotations":[84973],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010155"},{"annotations":[85895],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013584"},{"annotations":[86274],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012787"},{"annotations":[86311],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011246"},{"annotations":[86906],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008086"},{"annotations":[86999],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013337"},{"annotations":[85651],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008922"},{"annotations":[86254,86253],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014417"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited lipid metabolism disorder","termid":"MONDO:0002525"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00404":null,"SJAG_01356":null,"SJAG_01918":null,"SJAG_02119":null,"SJAG_02305":null,"SJAG_02885":null,"SJAG_04110":null,"SJAG_04178":null,"SJAG_04323":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005066"],"is_obsolete":false,"name":"disorder of phospholipids, sphingolipids and fatty acids biosynthesis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1843236","GARD:21516","UMLS:C5680990","Orphanet:352301"],"termid":"MONDO:0018117","terms_by_termid":{"MONDO:0008086":null,"MONDO:0008922":null,"MONDO:0010155":null,"MONDO:0011246":null,"MONDO:0012787":null,"MONDO:0013337":null,"MONDO:0013584":null,"MONDO:0013760":null,"MONDO:0014417":null},"xrefs":{"Monarch":{"xref_id":"0018117"}}}


id: PBO:0034749
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Unlike the human ortholog, this protein is not associated with the NADH complex. Fission yeast does not have the other 40 subunits that are present in that complex in mammals. See associated reference for more information on the human protein","termid":"PBO:0034749"}


id: MONDO:0024503
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm with neuroendocrine differentiation arising from the digestive system. It includes neuroendocrine tumors (well-differentiated endocrine tumors or carcinoid tumors and well differentiated endocrine carcinomas) and neuroendocrine carcinomas (poorly differentiated neuroendocrine carcinomas, small cell carcinomas, and large cell neuroendocrine carcinomas).","definition_xrefs":["NCIT:C27721"],"direct_ancestors":[{"relation_name":"is_a","term_name":"digestive system disorder","termid":"MONDO:0004335"},{"relation_name":"is_a","term_name":"neuroendocrine neoplasm","termid":"MONDO:0019496"},{"relation_name":"is_a","term_name":"digestive system neoplasm","termid":"MONDO:0021223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"digestive system neuroendocrine neoplasm","secondary_identifiers":["MEDGEN:232237","Orphanet:100092","MESH:C535650","UMLS:C1333799","GARD:2437"],"synonyms":[{"name":"GEP tumors","type":"related"},{"name":"GEP tumours","type":"related"},{"name":"GEP-NEN","type":"related"},{"name":"GEP-NET","type":"related"},{"name":"alimentary part of gastrointestinal system NET","type":"exact"},{"name":"alimentary part of gastrointestinal system neuroendocrine neoplasm","type":"exact"},{"name":"alimentary part of gastrointestinal system neuroendocrine tumor","type":"exact"},{"name":"alimentary part of gastrointestinal system neuroendocrine tumor, well differentiated, low or intermediate grade","type":"exact"},{"name":"alimentary part of gastrointestinal system neuroendocrine tumour","type":"exact"},{"name":"carcinoid tumor","type":"related"},{"name":"carcinoid tumor of digestive system","type":"exact"},{"name":"carcinoid tumour","type":"related"},{"name":"carcinoid tumour of digestive system","type":"exact"},{"name":"digestive system NET","type":"exact"},{"name":"digestive system neuroendocrine neoplasm","type":"exact"},{"name":"digestive system neuroendocrine tumor","type":"exact"},{"name":"digestive system neuroendocrine tumor, well differentiated, low or intermediate grade","type":"exact"},{"name":"digestive system neuroendocrine tumour","type":"exact"},{"name":"gastro-enteropancreatic neuroendocrine tumor","type":"exact"},{"name":"gastro-enteropancreatic neuroendocrine tumour","type":"exact"},{"name":"gastroenteropancreatic endocrine tumor","type":"exact"},{"name":"gastroenteropancreatic endocrine tumour","type":"exact"},{"name":"gastroenteropancreatic neuroendocrine neoplasm","type":"exact"},{"name":"gastrointestinal neuroendocrine neoplasm","type":"exact"},{"name":"gastrointestinal system neuroendocrine neoplasm","type":"exact"},{"name":"neuroendocrine neoplasm of alimentary part of gastrointestinal system","type":"exact"},{"name":"neuroendocrine neoplasm of digestive system","type":"exact"}],"termid":"MONDO:0024503","xrefs":{"Monarch":{"xref_id":"0024503"}}}


id: PBO:0111341
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SHREC complex subunit Clr2","termid":"PBO:0111341"}


id: PBO:0055508
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2942","termid":"PBO:0055508"}


id: PBO:0109433
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein-DNA covalent cross-linking repair protein","termid":"PBO:0109433"}


id: PBO:0052050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KANSL1 antisense RNA 1","termid":"PBO:0052050"}


id: PBO:0069951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1244, pseudogene","termid":"PBO:0069951"}


id: GO:0071982
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dormancy process","termid":"GO:0022611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"maintenance of diapause","termid":"GO:0071982"}


id: MONDO:0100002
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign inflammatory colitis caused by a non-IgE-mediated immune reaction to ingested food proteins.","definition_xrefs":["PMID:17584315"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gastrointestinal allergy","termid":"MONDO:0000777"},{"relation_name":"is_a","term_name":"proctocolitis","termid":"MONDO:0024278"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0005046"],"is_obsolete":false,"name":"food protein-induced allergic proctocolitis","secondary_identifiers":["UMLS:C4750318","MEDGEN:1663071"],"synonyms":[{"name":"FPIPC","type":"exact"},{"name":"allergic proctocolitis","type":"broad"},{"name":"milk protein proctocololitis","type":"narrow"}],"termid":"MONDO:0100002","xrefs":{"Monarch":{"xref_id":"0100002"}}}


id: MONDO:0007779
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Autosomal dominant form of Opitz G/BBB syndrome.","definition_xrefs":["MONDO:patterns/autosomal_dominant"],"gene_count":0,"genotype_count":0,"name":"obsolete autosomal dominant Opitz G/BBB syndrome (obsolete MONDO:0007779)","secondary_identifiers":["Orphanet:306588","OMIM:145410"],"synonyms":[{"name":"ADOS","type":"exact"},{"name":"BBB syndrome","type":"related"},{"name":"G syndrome","type":"related"},{"name":"GBBB syndrome","type":"related"},{"name":"GBBB2","type":"related"},{"name":"Opitz Bbbg syndrome","type":"related"},{"name":"Opitz G/BBB syndrome, autosomal dominant","type":"exact"},{"name":"Opitz GBBB syndrome, autosomal dominant","type":"related"},{"name":"Opitz GBBB syndrome, type 2","type":"related"},{"name":"Opitz GBBB syndrome, type II","type":"related"},{"name":"Opitz oculogenitolaryngeal syndrome, type 2","type":"related"},{"name":"Opitz-Frias syndrome","type":"related"},{"name":"Opitz-G syndrome, type 2","type":"related"},{"name":"autosomal dominant Opitz BBB/G syndrome","type":"exact"},{"name":"autosomal dominant Opitz syndrome","type":"exact"},{"name":"chromosome 22Q11.2 deletion syndrome, Opitz phenotype","type":"related"},{"name":"hypertelorism with esophageal Abnormality and hypospadias","type":"related"},{"name":"hypertelorism-hypospadias syndrome","type":"related"},{"name":"hypospadias-dysphagia syndrome","type":"related"},{"name":"telecanthus with associated abnormalities","type":"related"},{"name":"telecanthus-hypospadias syndrome","type":"related"}],"termid":"MONDO:0007779","xrefs":{"Monarch":{"xref_id":"0007779"}}}


id: GO:0007538
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The sex determination process that results in the initial specification of sexual status of an individual organism.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sex determination","termid":"GO:0007530"},{"relation_name":"part_of","term_name":"multicellular organism development","termid":"GO:0007275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"primary sex determination","termid":"GO:0007538"}


id: PBO:0080145
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vav guanine nucleotide exchange factor 1","termid":"PBO:0080145"}


id: MONDO:0010853
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Helicobacter pylori infection, susceptibility to","secondary_identifiers":["MEDGEN:325004","OMIM:600263","UMLS:C1838332"],"synonyms":[{"name":"H. pylori infection, susceptibility to","type":"exact"},{"name":"Helicobacter pylori infection, susceptibility to","type":"exact"}],"termid":"MONDO:0010853","xrefs":{"Monarch":{"xref_id":"0010853"}}}


id: GO:0032735
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cytokine production","termid":"GO:0001819"},{"relation_name":"is_a","term_name":"regulation of interleukin-12 production","termid":"GO:0032655"},{"relation_name":"positively_regulates","term_name":"interleukin-12 production","termid":"GO:0032615"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of interleukin-12 production","secondary_identifiers":["GO:0045084","GO:2001184"],"synonyms":[{"name":"activation of interleukin-12 production","type":"narrow"},{"name":"positive regulation of CLMF production","type":"related"},{"name":"positive regulation of IL-12 production","type":"exact"},{"name":"positive regulation of NKSF production","type":"related"},{"name":"positive regulation of interleukin-12 biosynthetic process","type":"narrow"},{"name":"positive regulation of interleukin-12 secretion","type":"narrow"},{"name":"stimulation of interleukin-12 production","type":"narrow"},{"name":"up regulation of interleukin-12 production","type":"exact"},{"name":"up-regulation of interleukin-12 production","type":"exact"},{"name":"upregulation of interleukin-12 production","type":"exact"}],"termid":"GO:0032735"}


id: PBO:0058129
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4431","termid":"PBO:0058129"}


id: PBO:0057999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3923","termid":"PBO:0057999"}


id: PBO:0068736
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U5A small nuclear 7, pseudogene","termid":"PBO:0068736"}


id: PBO:0087052
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L24B; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24B has a paralog, RPL24A, that arose from the whole genome duplication","termid":"PBO:0087052"}


id: SO:0001179
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"U3 snoRNA is a member of the box C/D class of small nucleolar RNAs. The U3 snoRNA secondary structure is characterised by a small 5' domain (with boxes A and A'), and a larger 3' domain (with boxes B, C, C', and D), the two domains being linked by a single-stranded hinge. Boxes B and C form the B/C motif, which appears to be exclusive to U3 snoRNAs, and boxes C' and D form the C'/D motif. The latter is functionally similar to the C/D motifs found in other snoRNAs. The 5' domain and the hinge region act as a pre-rRNA-binding domain. The 3' domain has conserved protein-binding sites. Both the box B/C and box C'/D motifs are sufficient for nuclear retention of U3 snoRNA. The box C'/D motif is also necessary for nucleolar localization, stability and hypermethylation of U3 snoRNA. Both box B/C and C'/D motifs are involved in specific protein interactions and are necessary for the rRNA processing functions of U3 snoRNA.","direct_ancestors":[{"relation_name":"is_a","term_name":"C_D_box_snoRNA","termid":"SO:0000593"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3_snoRNA","secondary_identifiers":["http://en.wikipedia.org/wiki/Small_nucleolar_RNA_U3"],"synonyms":[{"name":"U3 small nucleolar RNA","type":"exact"},{"name":"U3 snoRNA","type":"exact"},{"name":"small nucleolar RNA U3","type":"exact"},{"name":"snoRNA U3","type":"exact"}],"termid":"SO:0001179"}


id: PBO:0063285
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protocadherin gamma subfamily A, 11","termid":"PBO:0063285"}


id: PBO:0073648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"salt inducible kinase 2","termid":"PBO:0073648"}


id: GO:0034876
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete isonicotinic acid hydrazide hydrolase activity (obsolete GO:0034876)","termid":"GO:0034876"}


id: GO:0072120
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"animal organ maturation","termid":"GO:0048799"},{"relation_name":"part_of","term_name":"pronephros development","termid":"GO:0048793"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pronephros maturation","synonyms":[{"name":"pronephric kidney maturation","type":"exact"}],"termid":"GO:0072120"}


id: MONDO:0004512
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A meningeal melanoma with secondary diffuse meningeal spread. (WHO)","definition_xrefs":["NCIT:C6891"],"direct_ancestors":[{"relation_name":"is_a","term_name":"melanomatosis","termid":"MONDO:0004141"},{"relation_name":"is_a","term_name":"primary melanoma of the central nervous system","termid":"MONDO:0016747"},{"relation_name":"is_a","term_name":"malignant tumor of meninges","termid":"MONDO:0021322"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"meningeal melanomatosis","secondary_identifiers":["MEDGEN:226843","UMLS:C1266114","ICDO:8728/3","DOID:8243"],"synonyms":[{"name":"leptomeningeal melanomatosis","type":"related"},{"name":"melanomatosis of meningeal cluster","type":"exact"},{"name":"meningeal cluster melanomatosis","type":"exact"},{"name":"meningeal melanomatosis","type":"exact"},{"name":"meningeal melanomatosis (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0004512","xrefs":{"Monarch":{"xref_id":"0004512"}}}


id: PBO:0018273
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"condensin complex SMC subunit Smc2","termid":"PBO:0018273"}


id: MONDO:1012681
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any cone-rod dystrophy that occurs in dogs due to mutations in the RPGRIP1 and MAP9 genes.","definition_xrefs":["PMID:38752391","OMIA:001432-9615"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cone-rod dystrophy, non-human animal","termid":"MONDO:1012582"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cone-rod dystrophy, RPGRIP1-related and MAP9-related, dog","synonyms":[{"name":"RPGRIP1-CRD","type":"exact"},{"name":"canine progressive retinal atrophy","type":"related"},{"name":"cone-rod dystrophy 4, dog","type":"related"},{"name":"early-onset cone-rod dystrophy, dog","type":"related"}],"termid":"MONDO:1012681","xrefs":{"Monarch":{"xref_id":"1012681"}}}


id: PBO:0077492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMEM212 antisense RNA 1","termid":"PBO:0077492"}


id: PBO:0074718
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 78","termid":"PBO:0074718"}


id: PBO:0080059
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin specific peptidase 29","termid":"PBO:0080059"}


id: MONDO:0025152
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Diseases of chimpanzees, gorillas, and orangutans.","definition_xrefs":["MESH:D018420"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human primate disease","termid":"MONDO:0025013"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-human ape disease","synonyms":[{"name":"Pongidae disease","type":"related"},{"name":"Pongidae diseases","type":"related"},{"name":"ape disease","type":"related"},{"name":"disease, Pongidae","type":"related"},{"name":"disease, ape","type":"related"},{"name":"diseases, Pongidae","type":"related"},{"name":"diseases, ape","type":"related"}],"termid":"MONDO:0025152","xrefs":{"Monarch":{"xref_id":"0025152"}}}


id: PBO:0042245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine receptor 7","termid":"PBO:0042245"}


id: PATO:0001019
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A physical quality which inheres in a bearer by virtue of some influence is exerted by the bearer's mass per unit size.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"physical quality","termid":"PATO:0001018"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mass density","synonyms":[{"name":"density","type":"related"}],"termid":"PATO:0001019"}


id: PBO:0064113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polycystin 1 like 3, transient receptor potential channel interacting","termid":"PBO:0064113"}


id: MONDO:0018453
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete rare skin tumor or hamartoma (obsolete MONDO:0019300)","termid":"MONDO:0019300"},{"relation_name":"is_a","term_name":"integumentary system disorder","termid":"MONDO:0002051"},{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"familial atypical multiple mole melanoma syndrome","secondary_identifiers":["GARD:9281","MEDGEN:389220","NCIT:C27264","UMLS:C2314896","Orphanet:404560"],"synonyms":[{"name":"B-K mole syndrome","type":"exact"},{"name":"FAMM syndrome","type":"exact"},{"name":"FAMM-PC syndrome","type":"exact"},{"name":"FAMMM syndrome","type":"exact"},{"name":"familial Clark nevus syndrome","type":"exact"},{"name":"familial atypical mole melanoma syndrome","type":"exact"},{"name":"familial atypical mole syndrome","type":"exact"},{"name":"familial atypical multiple mole melanoma-pancreatic carcinoma syndrome","type":"exact"},{"name":"familial dysplastic nevus syndrome","type":"exact"},{"name":"melanoma-pancreatic cancer syndrome","type":"broad"}],"termid":"MONDO:0018453","xrefs":{"Monarch":{"xref_id":"0018453"}}}


id: MONDO:0020641
data:
  {"annotated_genes":["SJAG_04114","SJAG_03453","SJAG_00229","SJAG_03689"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86767,86768,87299],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008903"},{"annotations":[86313],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011014"}]},"cv_name":"mondo","definition":"A benign or malignant, primary or metastatic neoplasm involving the respiratory tract.","definition_xrefs":["NCIT:C3355"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm","termid":"MONDO:0005070"},{"relation_name":"is_a","term_name":"respiratory system disorder","termid":"MONDO:0005087"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00229":null,"SJAG_03453":null,"SJAG_03689":null,"SJAG_04114":null},"genotype_count":0,"is_obsolete":false,"name":"respiratory tract neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["EFO:0003853","SCTID:126667002","MEDGEN:11200","UMLS:C0035244","ICD10CM:C30-C39","MESH:D012142"],"synonyms":[{"name":"neoplasm of respiratory tract","type":"exact"},{"name":"neoplasm of the respiratory tract","type":"exact"},{"name":"neoplasm, respiratory tract","type":"exact"},{"name":"neoplasms, respiratory tract","type":"exact"},{"name":"respiratory system neoplasm","type":"exact"},{"name":"respiratory tract neoplasm","type":"exact"},{"name":"respiratory tract tumor","type":"exact"},{"name":"respiratory tract tumour","type":"exact"},{"name":"tract neoplasm, respiratory","type":"exact"},{"name":"tract neoplasms, respiratory","type":"exact"},{"name":"tumor of respiratory tract","type":"exact"},{"name":"tumor of the respiratory tract","type":"exact"},{"name":"tumour of respiratory tract","type":"exact"},{"name":"tumour of the respiratory tract","type":"exact"}],"termid":"MONDO:0020641","terms_by_termid":{"MONDO:0008903":null,"MONDO:0011014":null},"xrefs":{"Monarch":{"xref_id":"0020641"}}}


id: PBO:0063928
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoinositide-3-kinase regulatory subunit 6","termid":"PBO:0063928"}


id: FYPO:0001521
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of substance in cell during vegetative growth","termid":"FYPO:0001330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"increased cellular glutathione level during vegetative growth","synonyms":[{"name":"increased cellular GSH level during vegetative growth","type":"exact"},{"name":"increased cellular L-gamma-glutamyl-L-cysteinylglycine level during vegetative growth","type":"exact"},{"name":"increased cellular glutathione level during mitotic cell cycle","type":"related"},{"name":"increased cellular reduced glutathione level during vegetative growth","type":"exact"},{"name":"increased glutathione accumulation during vegetative growth","type":"related"}],"termid":"FYPO:0001521"}


id: GO:0035839
data:
  {"annotated_genes":["SJAG_00028","SJAG_03379","SJAG_02838","SJAG_04058","SJAG_03705","SJAG_01196","SJAG_00333","SJAG_00030","SJAG_03126"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[88714,91102,104654,109435,114061],"is_not":false,"summary":null,"term":"GO:0035839"},{"annotations":[117928,100927,110766,111959],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0140472"}]},"cv_name":"cellular_component","definition":"A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.","definition_xrefs":["GOC:expert_jd","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell tip","termid":"GO:0051286"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00028":null,"SJAG_00030":null,"SJAG_00333":null,"SJAG_01196":null,"SJAG_02838":null,"SJAG_03126":null,"SJAG_03379":null,"SJAG_03705":null,"SJAG_04058":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"non-growing cell tip","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"new cell end","type":"related"},{"name":"non-growing cell end","type":"exact"}],"termid":"GO:0035839","terms_by_termid":{"GO:0035839":null,"GO:0140472":null}}


id: GO:0048058
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"compound eye development","termid":"GO:0048749"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"compound eye corneal lens development","termid":"GO:0048058"}


id: PBO:0071364
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L29 pseudogene 23","termid":"PBO:0071364"}


id: GO:1905575
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to ganglioside GM3.","definition_xrefs":["GOC:TermGenie","GO_REF:0000067","PMID:1454804"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid binding","termid":"GO:0033293"},{"relation_name":"is_a","term_name":"ganglioside binding","termid":"GO:0035594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0008289"}],"interesting_parent_ids":["GO:0003674","GO:0008289","GO:0005488"],"is_obsolete":false,"name":"ganglioside GM3 binding","termid":"GO:1905575"}


id: MONDO:0017242
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cutaneous collagenous vasculopathy (CCV) is a primary microangiopathy confined to the skin, characterized by multiple and widespread telangiectasias.","definition_xrefs":["Orphanet:280779"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin vascular disease","termid":"MONDO:0019293"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"cutaneous collagenous vasculopathy","secondary_identifiers":["UMLS:C4305323","SCTID:718634003","icd11.foundation:878108553","MEDGEN:930992","GARD:12428"],"synonyms":[{"name":"CCV","type":"exact"},{"name":"cutaneus colagenous vasculopathy","type":"related"}],"termid":"MONDO:0017242","xrefs":{"Monarch":{"xref_id":"0017242"}}}


id: PBO:0050800
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5-hydroxytryptamine receptor 7 pseudogene 1","termid":"PBO:0050800"}


id: MONDO:0032924
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"primary ciliary dyskinesia","termid":"MONDO:0016575"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliary dyskinesia, primary, 45","secondary_identifiers":["MEDGEN:1714988","OMIM:618801","UMLS:C5394104","DOID:0111857","GARD:16383"],"synonyms":[{"name":"CILD45","type":"related"},{"name":"CILIARY DYSKINESIA, PRIMARY, 45","type":"related"},{"name":"Ciliary Dyskinesia, Primary, 45, Without Situs Inversus","type":"related"}],"termid":"MONDO:0032924","xrefs":{"Monarch":{"xref_id":"0032924"}}}


id: GO:0098988
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor activity","termid":"GO:0004930"},{"relation_name":"is_a","term_name":"glutamate receptor activity","termid":"GO:0008066"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"G protein-coupled glutamate receptor activity","synonyms":[{"name":"G-protein coupled glutamate receptor activity","type":"exact"}],"termid":"GO:0098988"}


id: GO:1990196
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.","definition_xrefs":["GOC:bhm","PMID:18955484","PMID:10879525","PMID:19254725"],"direct_ancestors":[{"relation_name":"is_a","term_name":"macrolide transmembrane transporter complex","termid":"GO:1990195"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"MacAB-TolC complex","synonyms":[{"name":"macrolide transporter MacAB-TolC complex","type":"exact"}],"termid":"GO:1990196"}


id: MOD:01531
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ8plex-113 reporter+balance group.","definition_xrefs":["Unimod:730#Y"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-tyrosine residue","termid":"MOD:00919"},{"relation_name":"is_a","term_name":"iTRAQ8plex-113 reporter+balance reagent acylated residue","termid":"MOD:01528"},{"relation_name":"is_a","term_name":"iTRAQ8plex reporter+balance reagent O-acylated residue","termid":"MOD:01714"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ8plex-113 reporter+balance reagent O4'-acylated tyrosine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry","type":"related"},{"name":"Representative mass and accurate mass for 113, 114, 116 & 117","type":"related"},{"name":"iTRAQ8plex","type":"related"},{"name":"iTRAQ8plex:13C(7)15N(1)","type":"related"}],"termid":"MOD:01531"}


id: GO:0032648
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of interferon-beta production.","definition_xrefs":["GOC:mah","PMID:15546383"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of type I interferon production","termid":"GO:0032479"},{"relation_name":"regulates","term_name":"interferon-beta production","termid":"GO:0032608"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of interferon-beta production","secondary_identifiers":["GO:0035547","GO:0045357"],"synonyms":[{"name":"regulation of IFN-beta production","type":"exact"},{"name":"regulation of interferon-beta biosynthetic process","type":"narrow"},{"name":"regulation of interferon-beta secretion","type":"narrow"}],"termid":"GO:0032648"}


id: MONDO:0018644
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant spastic paraplegia type 9","termid":"MONDO:0015091"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005559","MONDO:0000426","MONDO:0004736"],"is_obsolete":false,"name":"autosomal dominant complex spastic paraplegia type 9B","secondary_identifiers":["Orphanet:447757","GARD:21866","UMLS:C5568979","MEDGEN:1800402"],"synonyms":[{"name":"AD-SPG9B","type":"exact"}],"termid":"MONDO:0018644","xrefs":{"Monarch":{"xref_id":"0018644"}}}


id: PBO:0109393
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed transcript, Y-linked 21B","termid":"PBO:0109393"}


id: MONDO:1012293
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"subacute necrotising encephalopathy of Leigh, non-human animal","termid":"MONDO:1011863"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"subacute necrotising encephalopathy of Leigh, cattle","secondary_identifiers":["OMIA:001097-9913"],"termid":"MONDO:1012293","xrefs":{"Monarch":{"xref_id":"1012293"}}}


id: PBO:0044507
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytohesin 3","termid":"PBO:0044507"}


id: PR:Q10668
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- swi2 gene.","definition_xrefs":["UniProtKB:Q10668","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mating-type switching protein swi2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1142.03c","synonyms":[{"name":"Spom972h-swi2","type":"exact"}],"termid":"PR:Q10668"}


id: PBO:0090570
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THO complex subunit Tho7","termid":"PBO:0090570"}


id: GO:0032835
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.","definition_xrefs":["GOC:mtg_kidney_jan10","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"nephron development","termid":"GO:0072006"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glomerulus development","synonyms":[{"name":"glomerular development","type":"exact"}],"termid":"GO:0032835"}


id: GO:0032424
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.","definition_xrefs":["GOC:vk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mismatch repair","termid":"GO:0032423"},{"relation_name":"is_a","term_name":"negative regulation of DNA repair","termid":"GO:0045738"},{"relation_name":"negatively_regulates","term_name":"mismatch repair","termid":"GO:0006298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006281"},{"rel_name":"regulates","termid":"GO:0006281"},{"rel_name":"negatively_regulates","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006259","GO:0006281"],"is_obsolete":false,"name":"negative regulation of mismatch repair","synonyms":[{"name":"down regulation of mismatch repair","type":"exact"},{"name":"down-regulation of mismatch repair","type":"exact"},{"name":"downregulation of mismatch repair","type":"exact"},{"name":"inhibition of mismatch repair","type":"narrow"}],"termid":"GO:0032424"}


id: FYPO:0006828
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in the cytosol is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cellular zinc level","termid":"FYPO:0001552"},{"relation_name":"is_a","term_name":"increased level of substance in cytosol","termid":"FYPO:0001948"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"increased cytosolic zinc level","synonyms":[{"name":"increased cytosolic zinc ion level","type":"exact"},{"name":"increased cytosolic zinc ion level during vegetative growth","type":"exact"},{"name":"increased cytosolic zinc level during mitotic cell cycle","type":"related"},{"name":"increased level of zinc ions in cytosol","type":"exact"},{"name":"increased levels of free cytosolic zinc","type":"exact"}],"termid":"FYPO:0006828"}


id: MONDO:0009194
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare progressive disease that begins as a primary Epstein-Barr virus (EBV) infection. In this type of infection, the body makes too many lymphocytes (lymphoproliferative disease) for a period of more than 6 months duration. Lymphocytes are a type of white blood cell. They are an importantpart ofthe immune system because they help fight off diseases and protect the body from infection byproducing antibodies against viruses or bacteria and regulating immune responses. In CAEBV there are many antibodies againstEBV in the blood.Most people (about 95% of adults) get infected with EBV at some point in their lives, and never have any health problems.However, EBV can cause infectiousmononucleosis and other illnesses, and has a role in various autoimmune diseases and some types of cancer. While most infections occurring during childhood do not cause any symptoms,EBV infection in adolescents or young adults can often result in mononucleosis.After an EBV infection, the virus becomes latent (inactive) in the body, and, in some cases, the virus may reactivate. This does not always cause symptoms, but people with weakened immune systems are more likely to develop symptoms if EBV reactivates.In rare cases, people infected with EBV develop chronic active EBV virus infection(CAEBV) without apparent immunodeficiency. Most cases of CAEBV have been reported from Japan. These patientshave some of the complications found in otherwise-healthy patients with acute EBV infection, but unlike healthy patients, these complications persist and progress. Symptoms of CAEBV most often include fever, liverdysfunction, an enlarged spleen (splenomegaly), swollen lymph nodes (lymphadenopathy), and low numbers of platelets (thrombocytopenia) as well as high EBV-DNA load in the blood. Other features that appear in more than 10% of patients include enlarged liver (hepatomegaly), anemia, hypersensitivity to mosquito bites, rash, oral ulcers, hemophagocytic syndrome, coronary artery aneurysms, liver failure, lymphoma, and interstitial pneumonia. While the cause is yet unknown, researchers have identified defects in T cells or natural killer (NK) cells activity which results in a decreased defense against the EBV in people with CAEBV.It is important to note that the fatigue and malaise from acute infectious mononucleosis (IM)varies from mild symptoms lasting only a few weeks, to more severe symptoms of fatigue that can persist for several months, or even up to a year or more in up to 10% of patients (which may be considered a less severe form of chronicEBV infection). The persistence of fatigue that is seen in some patients after acute IM would lead some people to believe that EBV may also cause cases of chronic fatigue syndrome (CFS). However, no convincing link has been found between EBV and CFS.Hematopoietic stemcell transplantation has shown promise in the treatment of CAEBV.","definition_xrefs":["GARD:0009534"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"viral infectious disease","termid":"MONDO:0005108"},{"relation_name":"is_a","term_name":"post-viral disorder","termid":"MONDO:0021674"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunodeficiency 32B","secondary_identifiers":["NANDO:2200808","MEDGEN:865178","DOID:0111985","OMIM:226990","OMIM:614894","Orphanet:2566","GARD:9534","UMLS:C4016741"],"synonyms":[{"name":"CAEBV infection","type":"related"},{"name":"CAEBV syndrome","type":"exact"},{"name":"CEBV","type":"related"},{"name":"Epstein-Barr VIRUS, susceptibility to chronic infection by","type":"related"},{"name":"IMD32B","type":"exact"},{"name":"IRF8 deficiency, autosomal recessive","type":"exact"},{"name":"chronic EBV infection syndrome","type":"exact"},{"name":"chronic Epstein-Barr virus infection syndrome","type":"exact"},{"name":"chronic active Epstein-Barr disease","type":"related"},{"name":"chronic active Epstein-Barr virus infection","type":"related"},{"name":"immunodeficiency 32B","type":"exact"},{"name":"immunodeficiency 32B, monocyte and dendritic cell deficiency, autosomal recessive","type":"exact"},{"name":"immunodeficiency 32B, monocyte, Dendritic cell, and natural Killer cell deficiency, autosomal recessive","type":"exact"},{"name":"monocyte and dendritic cell deficiency, autosomal recessive","type":"exact"}],"termid":"MONDO:0009194","xrefs":{"Monarch":{"xref_id":"0009194"}}}


id: PBO:0065787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"queuine tRNA-ribosyltransferase catalytic subunit 1","termid":"PBO:0065787"}


id: GO:0072278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"comma-shaped body morphogenesis","termid":"GO:0072049"},{"relation_name":"part_of","term_name":"metanephric nephron morphogenesis","termid":"GO:0072273"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric comma-shaped body morphogenesis","termid":"GO:0072278"}


id: FYPO:0002344
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity phleomycin. Cells stop growing (and may die) at a concentration of phleomycin that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitive to DNA damaging agents","termid":"FYPO:0000266"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002683"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000139","FYPO:0000003","FYPO:0002683"],"is_obsolete":false,"name":"sensitive to phleomycin","synonyms":[{"name":"hypersensitive to phleomycin","type":"exact"},{"name":"sensitive to phleomycin during mitotic cell cycle","type":"related"},{"name":"sensitive to phleomycin during vegetative growth","type":"exact"}],"termid":"FYPO:0002344"}


id: PBO:0044787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin alpha 1","termid":"PBO:0044787"}


id: PBO:0089987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome complex subunit beta 1 Pre3","termid":"PBO:0089987"}


id: GO:0016570
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The covalent alteration of one or more amino acid residues within a histone protein.","definition_xrefs":["GOC:krc"],"gene_count":0,"genotype_count":0,"name":"obsolete histone modification (obsolete GO:0016570)","secondary_identifiers":["Wikipedia:Histone#Histone_modifications_in_chromatin_regulation"],"termid":"GO:0016570"}


id: PBO:0069952
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1245, pseudogene","termid":"PBO:0069952"}


id: PBO:0108949
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPOPL pseudogene 1","termid":"PBO:0108949"}


id: GO:0018667
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.","definition_xrefs":["EC:1.14.13.22"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"cyclohexanone monooxygenase activity","secondary_identifiers":["MetaCyc:CYCLOHEXANONE-MONOOXYGENASE-RXN","RHEA:24068","UM-BBD_reactionID:r0166"],"synonyms":[{"name":"cyclohexanone 1,2-monooxygenase activity","type":"exact"},{"name":"cyclohexanone oxygenase activity","type":"related"},{"name":"cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity","type":"related"},{"name":"cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)","type":"related"}],"termid":"GO:0018667"}


id: GO:1904304
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.","definition_xrefs":["PMID:10821044","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of smooth muscle contraction","termid":"GO:0006940"},{"relation_name":"regulates","term_name":"gastro-intestinal system smooth muscle contraction","termid":"GO:0014831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of gastro-intestinal system smooth muscle contraction","termid":"GO:1904304"}


id: PATO:0000398
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000398 vigorous (obsolete PATO:0000398)","termid":"PATO:0000398"}


id: MONDO:0014369
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome is a rare, genetic developmental defect during embryogenesis characterized primarily by congenital hypopituitarism and/or postaxial polydactyly. It can be associated with short stature, delayed bone age, hypogonadotropic hypogonadism, and/or midline facial defects (e.g. hypotelorism, mild midface hypoplasia, flat nasal bridge, and cleft lip and/or palate). Hypoplastic anterior pituitary and ectopic posterior pituitary lobe are frequent findings on MRI examination.","definition_xrefs":["Orphanet:420584"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"dysostosis","termid":"MONDO:0018234"},{"relation_name":"is_a","term_name":"non-acquired combined pituitary hormone deficiency","termid":"MONDO:0018762"},{"relation_name":"is_a","term_name":"congenital limb malformation","termid":"MONDO:0019054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0005497"],"is_obsolete":false,"name":"postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome","secondary_identifiers":["UMLS:C4014479","MEDGEN:862916","GARD:13349","DOID:0080328","OMIM:615849"],"synonyms":[{"name":"CJS","type":"related"},{"name":"Culler-Jones syndrome","type":"related"},{"name":"Pallister-Hall syndrome 2","type":"related"},{"name":"Pallister-Hall syndrome 2, formerly","type":"related"}],"termid":"MONDO:0014369","xrefs":{"Monarch":{"xref_id":"0014369"}}}


id: FYPO:0006297
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which the processed 5.8S ribosomal RNA is longer than normal.","definition_xrefs":["PMID:18438419","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985"],"is_obsolete":false,"name":"increased 5.8S rRNA length","synonyms":[{"name":"increased 5.8S ribosomal RNA length","type":"exact"},{"name":"increased length of 5.8S rRNA","type":"exact"}],"termid":"FYPO:0006297"}


id: PBO:0050369
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 pseudogene 72","termid":"PBO:0050369"}


id: FYPO:0007046
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which alkaline phosphatase activity is absent during a cellular response to zinc ion starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished alkaline phosphatase activity","termid":"FYPO:0007043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0000654","FYPO:0000661","FYPO:0000652","FYPO:0001985"],"is_obsolete":false,"name":"abolished alkaline phosphatase activity during cellular response to zinc ion starvation","synonyms":[{"name":"abolished alkaline phosphatase activity during cellular response to zinc ion depletion","type":"exact"},{"name":"abolished alkaline phosphatase activity during cellular response to zinc ion deprivation","type":"exact"},{"name":"abolished alkaline phosphatase activity during cellular response to zinc ion limitation","type":"exact"},{"name":"abolished alkaline phosphatase activity during cellular response to zinc starvation","type":"exact"},{"name":"alkaline phosphatase activity abolished during cellular response to zinc ion starvation","type":"exact"}],"termid":"FYPO:0007046"}


id: GO:0098516
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events in which high humidity is detected and converted into a molecular signal.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of humidity","termid":"GO:0098513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of high humidity","termid":"GO:0098516"}


id: GO:0110118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.","definition_xrefs":["PMID:16377567","GOC:ha"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of photoreceptor cell differentiation","termid":"GO:0046533"},{"relation_name":"is_a","term_name":"regulation of compound eye photoreceptor cell differentiation","termid":"GO:0110116"},{"relation_name":"negatively_regulates","term_name":"compound eye photoreceptor cell differentiation","termid":"GO:0001751"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of compound eye photoreceptor cell differentiation","termid":"GO:0110118"}


id: _global:assayed_using
data:
  {"annotation_feature_type":"gene","cv_name":"fypo_extension_relations","definition":"Relation between a phenotype and an entity, such as a gene product that acts as an enzyme or substrate, with which the phenotype was assayed.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"assayed_using","termid":"_global:assayed_using"}


id: MONDO:0020167
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete malposition of external canthus (obsolete MONDO:0020167)","secondary_identifiers":["Orphanet:98576"],"termid":"MONDO:0020167","xrefs":{"Monarch":{"xref_id":"0020167"}}}


id: SO:0000043
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A pseudogene created via retrotranposition of the mRNA of a functional protein-coding parent gene followed by accumulation of deleterious mutations lacking introns and promoters, often including a polyA tail.","definition_xrefs":["GENCODE:http://www.gencodegenes.org/gencode_biotypes.html"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pseudogene","termid":"SO:0000336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"processed_pseudogene","synonyms":[{"name":"INSDC_feature:gene","type":"broad"},{"name":"INSDC_qualifier:processed","type":"exact"},{"name":"R psi G","type":"related"},{"name":"processed pseudogene","type":"exact"},{"name":"pseudogene by reverse transcription","type":"related"},{"name":"retropseudogene","type":"exact"}],"termid":"SO:0000043"}


id: PBO:0010081
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"human ISCA1 orholog","termid":"PBO:0010081"}


id: PBO:0003903
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar copper transporter Ctr6","termid":"PBO:0003903"}


id: PATO:0001307
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A variability of temperature which is relatively low.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"variant temperature","termid":"PATO:0001314"},{"relation_name":"is_a","term_name":"decreased process quality","termid":"PATO:0002302"},{"relation_name":"is_a","term_name":"decreased object quality","termid":"PATO:0002303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased variability of temperature","synonyms":[{"name":"low variability of temperature","type":"exact"}],"termid":"PATO:0001307"}


id: GO:0005385
data:
  {"annotated_genes":["SJAG_04185","SJAG_01990","SJAG_03528","SJAG_00328","SJAG_00222","SJAG_01803","SJAG_01078"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74525,75790,77088,78242,104319,114360],"is_not":false,"summary":null,"term":"GO:0005385"},{"annotations":[104178],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000006"}]},"cv_name":"molecular_function","definition":"Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.","definition_xrefs":["GOC:dgf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transition metal ion transmembrane transporter activity","termid":"GO:0046915"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00222":null,"SJAG_00328":null,"SJAG_01078":null,"SJAG_01803":null,"SJAG_01990":null,"SJAG_03528":null,"SJAG_04185":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"zinc ion transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-9820566","Reactome:R-HSA-442422","Reactome:R-HSA-442387","Reactome:R-HSA-437085","Reactome:R-HSA-442393","Reactome:R-HSA-435366","Reactome:R-HSA-437139","Reactome:R-HSA-442317","Reactome:R-HSA-442405","MetaCyc:RXN0-12","Reactome:R-HSA-5654125","Reactome:R-HSA-437136","Reactome:R-HSA-437084","Reactome:R-HSA-435375","Reactome:R-HSA-442345"],"synonyms":[{"name":"cobalt, zinc uptake permease activity","type":"related"},{"name":"zinc, cadmium uptake permease activity","type":"related"},{"name":"zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity","type":"related"},{"name":"zinc, iron permease activity","type":"narrow"}],"termid":"GO:0005385","terms_by_termid":{"GO:0000006":null,"GO:0005385":null}}


id: PBO:0078249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor beta variable 25/OR9-2 (pseudogene)","termid":"PBO:0078249"}


id: PBO:0081820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 737","termid":"PBO:0081820"}


id: PBO:0000512
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3'-tRNA processing endonuclease tRNAse Z L2 Trz1 (predicted)","termid":"PBO:0000512"}


id: PBO:0071634
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L36a pseudogene 53","termid":"PBO:0071634"}


id: MONDO:0031004
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete genetic disorder of sex development of gynecological interest (obsolete MONDO:0031004)","secondary_identifiers":["Orphanet:325665"],"termid":"MONDO:0031004","xrefs":{"Monarch":{"xref_id":"0031004"}}}


id: MONDO:0003607
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neuritis that involves the forelimb.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"mononeuritis simplex","termid":"MONDO:0002121"},{"relation_name":"is_a","term_name":"neuritis","termid":"MONDO:0002122"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"neuritis of upper limb","secondary_identifiers":["MEDGEN:509640","DOID:572","ICD9:354","UMLS:C0154741"],"synonyms":[{"name":"forelimb neuritis","type":"exact"},{"name":"neuritis of forelimb","type":"exact"}],"termid":"MONDO:0003607","xrefs":{"Monarch":{"xref_id":"0003607"}}}


id: PBO:0075279
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 19 pseudogene 4","termid":"PBO:0075279"}


id: GO:0009472
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete cytochrome c3 (tetraheme) (obsolete GO:0009472)","synonyms":[{"name":"cytochrome c3 (tetraheme)","type":"exact"}],"termid":"GO:0009472"}


id: PBO:0084680
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial beta-keto-acyl synthase; possible role in fatty acid synthesis; required for mitochondrial respiration; human homolog OXSM can complement yeast cem1 null mutant","termid":"PBO:0084680"}


id: GO:1900139
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of icosanoid secretion","termid":"GO:0032304"},{"relation_name":"is_a","term_name":"regulation of arachidonate secretion","termid":"GO:0090237"},{"relation_name":"negatively_regulates","term_name":"arachidonate secretion","termid":"GO:0050482"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of arachidonate secretion","synonyms":[{"name":"down regulation of arachidonic acid secretion","type":"exact"},{"name":"down-regulation of arachidonic acid secretion","type":"exact"},{"name":"downregulation of arachidonic acid secretion","type":"exact"},{"name":"inhibition of arachidonic acid secretion","type":"narrow"},{"name":"negative regulation of arachidonic acid secretion","type":"exact"}],"termid":"GO:1900139"}


id: PBO:0052610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KRAB box domain containing 1","termid":"PBO:0052610"}


id: PBO:0038549
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ABHD17A pseudogene 4","termid":"PBO:0038549"}


id: GO:0140882
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of zinc ions from a cell, into the extracellular region.","definition_xrefs":["PMID:17355957"],"direct_ancestors":[{"relation_name":"is_a","term_name":"zinc ion transmembrane transport","termid":"GO:0071577"},{"relation_name":"is_a","term_name":"export across plasma membrane","termid":"GO:0140115"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0055085","GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"zinc export across plasma membrane","synonyms":[{"name":"zinc ion export from cell","type":"exact"}],"termid":"GO:0140882"}


id: PR:P49777
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A tigger transposable element-derived protein 4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03736"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARS-binding protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1105.04c","secondary_identifiers":["UniProtKB:P49777"],"synonyms":[{"name":"Spom972h-TIGD4","type":"exact"}],"termid":"PR:P49777"}


id: PBO:0077478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 200A","termid":"PBO:0077478"}


id: MONDO:0007994
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"thanatophoric dysplasia type 2","termid":"MONDO:0008547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"micromelic bone dysplasia with cloverleaf skull","secondary_identifiers":["MESH:C536429","UMLS:C1834928","OMIM:156830","GARD:1404","MEDGEN:322531"],"synonyms":[{"name":"micromelic bone dysplasia with cloverleaf skull","type":"exact"}],"termid":"MONDO:0007994","xrefs":{"Monarch":{"xref_id":"0007994"}}}


id: MONDO:0003333
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mature monodermal teratoma that arises from the ovary and is characterized by the presence of benign, thyroid-type tissues.","definition_xrefs":["NCIT:C40012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovarian benign neoplasm","termid":"MONDO:0000646"},{"relation_name":"is_a","term_name":"struma ovarii","termid":"MONDO:0006980"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign struma ovarii","secondary_identifiers":["DOID:5209"],"synonyms":[{"name":"benign struma ovarii","type":"exact"},{"name":"struma ovarii, benign","type":"exact"}],"termid":"MONDO:0003333","xrefs":{"Monarch":{"xref_id":"0003333"}}}


id: GO:0031033
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"actin cytoskeleton organization","termid":"GO:0030036"},{"relation_name":"is_a","term_name":"supramolecular fiber organization","termid":"GO:0097435"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0030036"}],"interesting_parent_ids":["GO:0008150","GO:0030036","GO:0007010"],"is_obsolete":false,"name":"myosin filament organization","synonyms":[{"name":"myosin filament assembly or disassembly","type":"related"},{"name":"myosin filament organisation","type":"exact"},{"name":"myosin polymerization or depolymerization","type":"related"}],"termid":"GO:0031033"}


id: PBO:0065286
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline rich transmembrane protein 1B","termid":"PBO:0065286"}


id: PR:Q9Y7L7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A phosphatidylinositol N-acetylglucosaminyltransferase subunit H that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR15231:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol N-acetylglucosaminyltransferase subunit gpi15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC685.05","secondary_identifiers":["UniProtKB:Q9Y7L7"],"synonyms":[{"name":"PIGH homolog (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPBC685.05","type":"related"},{"name":"Spom972h-PIGH","type":"exact"}],"termid":"PR:Q9Y7L7"}


id: GO:0006891
data:
  {"annotated_genes":["SJAG_02750","SJAG_02525","SJAG_01415","SJAG_00578","SJAG_02211","SJAG_04474","SJAG_04739","SJAG_00330","SJAG_02316","SJAG_01459","SJAG_01508","SJAG_04070","SJAG_03467","SJAG_03842","SJAG_04569","SJAG_01071","SJAG_04023","SJAG_03663","SJAG_00804","SJAG_05030","SJAG_01600","SJAG_03158","SJAG_00192","SJAG_04358","SJAG_02655","SJAG_04021","SJAG_00041","SJAG_00332","SJAG_04002","SJAG_04837","SJAG_03054","SJAG_02234"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[57462,69386,69929,70159,70755,71290,73448,75172,75934,77294,77990,78326,78766,79844,88619,96275,97296,97733,98451,99762,100337,102534,103377,104908,107141,109577,109840],"is_not":false,"summary":null,"term":"GO:0006891"},{"annotations":[98088],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048219"},{"annotations":[88918,116860,109513,91115],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000301"}]},"cv_name":"biological_process","definition":"The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).","definition_xrefs":["ISBN:0716731363"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Golgi vesicle transport","termid":"GO:0048193"}],"gene_count":32,"genes_by_uniquename":{"SJAG_00041":null,"SJAG_00192":null,"SJAG_00330":null,"SJAG_00332":null,"SJAG_00578":null,"SJAG_00804":null,"SJAG_01071":null,"SJAG_01415":null,"SJAG_01459":null,"SJAG_01508":null,"SJAG_01600":null,"SJAG_02211":null,"SJAG_02234":null,"SJAG_02316":null,"SJAG_02525":null,"SJAG_02655":null,"SJAG_02750":null,"SJAG_03054":null,"SJAG_03158":null,"SJAG_03467":null,"SJAG_03663":null,"SJAG_03842":null,"SJAG_04002":null,"SJAG_04021":null,"SJAG_04023":null,"SJAG_04070":null,"SJAG_04358":null,"SJAG_04474":null,"SJAG_04569":null,"SJAG_04739":null,"SJAG_04837":null,"SJAG_05030":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0016192","GO:0008150"],"is_obsolete":false,"name":"intra-Golgi vesicle-mediated transport","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"intra-Golgi transport","type":"exact"}],"termid":"GO:0006891","terms_by_termid":{"GO:0000301":null,"GO:0006891":null,"GO:0048219":null}}


id: MONDO:0000918
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute or chronic, usually bacterial infectious process affecting the endometrium. It may extend to the myometrium and parametrial tissues. Symptoms include lower abdominal pain, vaginal discharge, and vaginal bleeding.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endometrial disorder","termid":"MONDO:0000931"},{"relation_name":"is_a","term_name":"mucositis","termid":"MONDO:0020579"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endometritis","secondary_identifiers":["EFO:1001312","MEDGEN:41789","MESH:D004716","SCTID:78623009","UMLS:C0014179","DOID:1002","NCIT:C26764"],"synonyms":[{"name":"endometrium inflammation","type":"exact"},{"name":"inflammation of endometrium","type":"exact"},{"name":"uterine infection","type":"exact"}],"termid":"MONDO:0000918","xrefs":{"Monarch":{"xref_id":"0000918"}}}


id: FYPO:0005495
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah","PMID:26108447"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased transcription during vegetative growth","termid":"FYPO:0000780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000294","FYPO:0000002","FYPO:0001320","FYPO:0006551"],"is_obsolete":false,"name":"increased transcription from CRE promoter","synonyms":[{"name":"expression of CRE target genes increased","type":"related"},{"name":"increased transcription from CRE promoter during mitotic cell cycle","type":"related"},{"name":"increased transcription from CRE promoter during vegetative growth","type":"exact"}],"termid":"FYPO:0005495"}


id: MONDO:0022790
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cleft tongue","secondary_identifiers":["MEDGEN:82731","UMLS:C0266111"],"synonyms":[{"name":"bifid tongue","type":"related"},{"name":"cleft tongue syndrome","type":"related"}],"termid":"MONDO:0022790","xrefs":{"Monarch":{"xref_id":"0022790"}}}


id: PBO:0066644
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulating synaptic membrane exocytosis 2","termid":"PBO:0066644"}


id: PBO:0005333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"triosephosphate isomerase","termid":"PBO:0005333"}


id: PBO:0088069
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin-specific protease; removes ubiquitin from ubiquitinated proteins; controls K63 homeostasis during oxidative stress; deubiquitinates Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity","termid":"PBO:0088069"}


id: PBO:0048900
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A6 family like 24","termid":"PBO:0048900"}


id: GO:0035873
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.","definition_xrefs":["GOC:mcc","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lactate transport","termid":"GO:0015727"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transport","termid":"GO:1905039"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"lactate transmembrane transport","synonyms":[{"name":"lactate membrane transport","type":"exact"}],"termid":"GO:0035873"}


id: MONDO:0016249
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ovarian cancer caused by germline mutations in various genes, usually associated with additional cancer risks. The most common are breast and ovarian cancer syndrome (HBOC) due to mutations in BRCA1 and BRCA2 genes and hereditary nonpolyposis colorectal cancer (HNPCC) due to mutations in DNA mismatch-repair genes. Mutations in STK11 gene, causing Peutz-Jeghers syndrome, are also associated with a risk of ovarian cancer (typically sex cord stromal tumors). Mutations in other genes, including RAD51C, RAD51D, PALB2, confer an elevated ovarian cancer risk in a minority of patients.","definition_xrefs":["Orphanet:213524"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial ovarian cancer","termid":"MONDO:0016248"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"hereditary site-specific ovarian cancer syndrome","secondary_identifiers":["icd11.foundation:123305976","MEDGEN:1650574","GARD:20468","UMLS:C4749652"],"termid":"MONDO:0016249","xrefs":{"Monarch":{"xref_id":"0016249"}}}


id: PBO:0082218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress","termid":"PBO:0082218"}


id: PBO:0044076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cleavage stimulation factor subunit 3","termid":"PBO:0044076"}


id: PBO:0110192
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NaTtoU","termid":"PBO:0110192"}


id: MONDO:0054637
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Noonan syndrome-like disorder with loose anagen hair","termid":"MONDO:0011899"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"Noonan syndrome-like disorder with loose anagen hair 1","secondary_identifiers":["OMIM:607721","UMLS:C4478716","MEDGEN:1379805","NCIT:C176939","DOID:0080692"],"synonyms":[{"name":"NSLH","type":"broad"},{"name":"NSLH1","type":"exact"},{"name":"Noonan syndrome-like disorder with loose anagen hair 1","type":"exact"},{"name":"Noonan syndrome-like with loose anagen hair 1","type":"exact"},{"name":"Tosti syndrome","type":"related"}],"termid":"MONDO:0054637","xrefs":{"Monarch":{"xref_id":"0054637"}}}


id: PBO:0001159
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxisomal defects","termid":"PBO:0001159"}


id: MONDO:0030981
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"severe combined immunodeficiency","termid":"MONDO:0015974"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 79","secondary_identifiers":["GARD:9523","OMIM:619238","MEDGEN:1783683","UMLS:C5543220","DOID:0112277"],"synonyms":[{"name":"CD4 Deficiency","type":"exact"},{"name":"IMD79","type":"exact"},{"name":"immunodeficiency 79","type":"exact"}],"termid":"MONDO:0030981","xrefs":{"Monarch":{"xref_id":"0030981"}}}


id: PBO:0084998
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N alpha-acetyl-transferase; involved in acetylation of the N-terminal residues of histones H4 and H2A","termid":"PBO:0084998"}


id: GO:0010978
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation.","definition_xrefs":["GOC:tb","GOC:dph","GOC:jp"],"gene_count":0,"genotype_count":0,"name":"obsolete gene silencing involved in chronological cell aging (obsolete GO:0010978)","termid":"GO:0010978"}


id: MONDO:0014619
data:
  {"annotated_genes":["SJAG_01207"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85258],"is_not":false,"summary":null,"term":"MONDO:0014619"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"photosensitive trichothiodystrophy","termid":"MONDO:0002470"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01207":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021190"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0021190","MONDO:0005093"],"is_obsolete":false,"name":"trichothiodystrophy 3, photosensitive","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16102","MEDGEN:865608","OMIM:616395","UMLS:C4017171","NCIT:C173099","DOID:0111871"],"synonyms":[{"name":"TTD3","type":"related"},{"name":"trichothiodystrophy 3, photosensitive","type":"exact"},{"name":"trichothiodystrophy, complementation group A","type":"related"}],"termid":"MONDO:0014619","terms_by_termid":{"MONDO:0014619":null},"xrefs":{"Monarch":{"xref_id":"0014619"}}}


id: PBO:0073159
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SEC61G divergent transcript","termid":"PBO:0073159"}


id: PBO:0050038
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"major histocompatibility complex, class II, DR beta 6 (pseudogene)","termid":"PBO:0050038"}


id: MONDO:1012886
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Parkinson disease that occurs in white-tufted-ear marmosets due to a mutation in the LRRK2 gene created by genetic engineering or gene editing.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Parkinson disease, non-human animal","termid":"MONDO:1012984"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Parkinson disease, LRRK2-related, white-tufted-ear marmoset","secondary_identifiers":["OMIA:002379-9483"],"termid":"MONDO:1012886","xrefs":{"Monarch":{"xref_id":"1012886"}}}


id: PBO:0113301
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in calcium-induced activation of calcineurin; homologous to proteins in Candida and Cryptococcus; YCX1 is not an essential protein","termid":"PBO:0113301"}


id: FYPO:0003867
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of ubiquitinated protein measured in the cell is higher than normal when the cell is in G0 phase. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah","PMID:20133687"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein level during G0","termid":"FYPO:0003866"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0006551","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"increased level of ubiquitinated protein in cell during G0","synonyms":[{"name":"increased accumulation of ubiquitinated protein in cell during G0","type":"related"},{"name":"increased level of ubiquitinated protein in cell during cell quiescence","type":"exact"},{"name":"increased level of ubiquitinated protein in cell during quiescence","type":"exact"},{"name":"increased ubiquitinated protein level during G0","type":"exact"}],"termid":"FYPO:0003867"}


id: PBO:0034673
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_break-induced_loss_of_heterozygosity_via_chromosomal_translocation","termid":"PBO:0034673"}


id: PBO:0076504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taste 2 receptor member 4","termid":"PBO:0076504"}


id: PBO:0033833
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic fizzy-related APC coactivator Fzr3","termid":"PBO:0033833"}


id: GO:1990719
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections.","definition_xrefs":["PMID:21586547","PMID:9295136","GOC:cilia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"axonemal microtubule","termid":"GO:0005879"},{"relation_name":"part_of","term_name":"axonemal central pair","termid":"GO:0097540"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0015630"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0015630","GO:0005575"],"is_obsolete":false,"name":"C1 axonemal microtubule","synonyms":[{"name":"C1 tubule","type":"broad"}],"termid":"GO:1990719"}


id: MONDO:0015009
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"lymphatic malformation","termid":"MONDO:0019313"},{"relation_name":"is_a","term_name":"EPHB4-associated vascular malformation spectrum","termid":"MONDO:0700080"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"lymphatic malformation 7","secondary_identifiers":["UMLS:C4310629","MEDGEN:934596","OMIM:617300"],"synonyms":[{"name":"HFASD","type":"exact"},{"name":"hydrops fetalis, nonimmune, and/or atrial septal defect, susceptibility to","type":"exact"},{"name":"hydrops fetalis, nonimmune, and/or atrial septal defect, susceptibility to; HFASD","type":"exact"}],"termid":"MONDO:0015009","xrefs":{"Monarch":{"xref_id":"0015009"}}}


id: MONDO:1010243
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cerebellar degeneration that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurodegenerative disease, non-human animal","termid":"MONDO:1012953"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebellar degeneration, non-human animal","secondary_identifiers":["OMIA:001221"],"termid":"MONDO:1010243","xrefs":{"Monarch":{"xref_id":"1010243"}}}


id: PBO:0028855
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_RNA_level_during_glucose_starvation","termid":"PBO:0028855"}


id: MONDO:0030046
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id: PBO:0004332
data:
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id: PBO:0012603
data:
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id: GO:0046320
data:
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