# terms

id: PBO:0029794
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_rate_of_actin_cable_retrograde_transport","termid":"PBO:0029794"}


id: MONDO:0958233
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Bethlem myopathy","termid":"MONDO:0008029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0002320"],"is_obsolete":false,"name":"Bethlem myopathy 1B","secondary_identifiers":["MEDGEN:1859128","OMIM:620725","UMLS:C5935580"],"termid":"MONDO:0958233","xrefs":{"Monarch":{"xref_id":"0958233"}}}


id: PBO:0030352
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_nuclear_export_during_cellular_hypotonic_salinity_response","termid":"PBO:0030352"}


id: GO:0060666
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a salivary epithelial cord bifurcates at its end.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dichotomous subdivision of an epithelial terminal unit","termid":"GO:0060600"},{"relation_name":"part_of","term_name":"branching involved in salivary gland morphogenesis","termid":"GO:0060445"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dichotomous subdivision of terminal units involved in salivary gland branching","termid":"GO:0060666"}


id: GO:2000630
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of RNA metabolic process","termid":"GO:0051254"},{"relation_name":"is_a","term_name":"regulation of miRNA metabolic process","termid":"GO:2000628"},{"relation_name":"positively_regulates","term_name":"miRNA metabolic process","termid":"GO:0010586"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of miRNA metabolic process","synonyms":[{"name":"positive regulation of microRNA metabolic process","type":"exact"}],"termid":"GO:2000630"}


id: PR:Q9P7K0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A mitochondrial import inner membrane translocase subunit Tim9 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO04500","PANTHER:PTHR10898:SF10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial import inner membrane translocase subunit tim9 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC24B10.05","secondary_identifiers":["UniProtKB:Q9P7K0"],"synonyms":[{"name":"Spom972h-TIMM9","type":"exact"}],"termid":"PR:Q9P7K0"}


id: PBO:0026757
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_after_spore_germination,_multiple_cell_divisions,_septated_cell_with_condensed_chromatin","termid":"PBO:0026757"}


id: PR:O13706
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- hpz2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13706"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PARP-type zinc finger-containing protein C13F5.07c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC13F5.07c","synonyms":[{"name":"Spom972h-hpz2","type":"exact"}],"termid":"PR:O13706"}


id: PBO:0113201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Methionine-R-sulfoxide reductase; reduces the R enantiomer of free Met-SO, in contrast to Ycl033Cp which reduces Met-R-SO in a peptide linkage; has a role in protection against oxidative stress; capable of binding and degrading patulin, a polyketide mycotoxin, forming E-ascladiol; relative distribution to the nucleus increases upon DNA replication stress","termid":"PBO:0113201"}


id: PBO:0043042
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chondrolectin","termid":"PBO:0043042"}


id: GO:0052455
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The alteration by an organism of the levels of jasmonic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by organism of jasmonic acid levels in symbiont (obsolete GO:0052455)","synonyms":[{"name":"modulation by organism of jasmonic acid levels in symbiont","type":"exact"}],"termid":"GO:0052455"}


id: GO:0090586
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).","definition_xrefs":["PMID:8246840"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-phosphocysteine-sugar phosphotransferase activity","termid":"GO:0090563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0003824","GO:0003674","GO:0022857","GO:0016740"],"is_obsolete":false,"name":"protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity","termid":"GO:0090586"}


id: MONDO:0002763
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A verrucous carcinoma that involves the urethra.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urethra squamous cell carcinoma","termid":"MONDO:0002764"},{"relation_name":"is_a","term_name":"verrucous carcinoma","termid":"MONDO:0006006"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"urethral verrucous carcinoma","secondary_identifiers":["DOID:3749","MEDGEN:274359","NCIT:C39874","UMLS:C1519827"],"synonyms":[{"name":"urethra verrucous carcinoma","type":"exact"},{"name":"urethral verrucous carcinoma","type":"exact"}],"termid":"MONDO:0002763","xrefs":{"Monarch":{"xref_id":"0002763"}}}


id: MONDO:0009672
data:
  {"annotated_genes":["SJAG_03894"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85848],"is_not":false,"summary":null,"term":"MONDO:0009672"}]},"cv_name":"mondo","definition":"Proximal spinal muscular atrophy type 3 (SMA3) is a relatively mild form of proximal spinal muscular atrophy characterized by muscle weakness and hypotonia resulting from the degeneration and loss of the lower motor neurons in the spinal cord and the brain stem nuclei.","definition_xrefs":["Orphanet:83419"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proximal spinal muscular atrophy","termid":"MONDO:0019079"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03894":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005244","MONDO:0005559"],"is_obsolete":false,"name":"spinal muscular atrophy, type III","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:198","MEDGEN:101816","ICD9:335.11","NORD:1342","DOID:12376","icd11.foundation:677572815","SCTID:54280009","NANDO:1200006","NCIT:C118847","OMIM:253400","UMLS:C0152109"],"synonyms":[{"name":"KWS","type":"related"},{"name":"Kugelberg Welander Syndrome","type":"exact"},{"name":"Kugelberg-Welander disease","type":"exact"},{"name":"Kugelberg-Welander syndrome","type":"related"},{"name":"SMA 3","type":"related"},{"name":"SMA type 3","type":"exact"},{"name":"SMA type III","type":"exact"},{"name":"SMA-III","type":"exact"},{"name":"SMA3","type":"exact"},{"name":"Sma 3","type":"related"},{"name":"childhood spinal muscular atrophy","type":"broad"},{"name":"juvenile spinal muscular atrophy","type":"broad"},{"name":"muscular atrophy, juvenile","type":"related"},{"name":"paediatric spinal muscular atrophy","type":"related"},{"name":"pediatric spinal muscular atrophy","type":"related"},{"name":"proximal spinal muscular atrophy type 3","type":"related"},{"name":"spinal muscular atrophy III","type":"exact"},{"name":"spinal muscular atrophy of childhood","type":"related"},{"name":"spinal muscular atrophy type 3","type":"exact"},{"name":"spinal muscular atrophy, familial","type":"exact"},{"name":"spinal muscular atrophy, mild childhood and adolescent form","type":"related"},{"name":"spinal muscular atrophy, type 3","type":"related"},{"name":"spinal muscular atrophy, type III","type":"exact"},{"name":"spinal muscular atrophy, type III, modifier of","type":"exact"},{"name":"spinal muscular atrophy-3","type":"exact"},{"name":"type III spinal muscular atrophy","type":"exact"}],"termid":"MONDO:0009672","terms_by_termid":{"MONDO:0009672":null},"xrefs":{"Monarch":{"xref_id":"0009672"}}}


id: FYPO:0007629
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a normal proportion of cells in the population remains viable during G0 phase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population viability","termid":"FYPO:0002057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0000003"],"is_obsolete":false,"name":"normal viability during G0","synonyms":[{"name":"maintains viability in G0","type":"exact"},{"name":"normal G0 maintenance","type":"exact"},{"name":"normal cell population viability during G0","type":"exact"},{"name":"normal viability during cell quiescence","type":"exact"},{"name":"normal viability during quiescence","type":"exact"},{"name":"normal viability in G0","type":"exact"}],"termid":"FYPO:0007629"}


id: GO:0140348
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.","definition_xrefs":["PMID:26945070"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycerophospholipid flippase activity","termid":"GO:0140333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140303"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0140303"],"is_obsolete":false,"name":"lysophosphatidylcholine flippase activity","synonyms":[{"name":"lysophosphatidylcholine flippase activity (exoplasmic to cytosolic leaflet)","type":"exact"}],"termid":"GO:0140348"}


id: PBO:0075506
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPC24 component of NDC80 kinetochore complex","termid":"PBO:0075506"}


id: PBO:0038640
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acyl-CoA thioesterase 7","termid":"PBO:0038640"}


id: MONDO:0004426
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A meningioma that affects the frontal sulcus.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebral convexity meningioma","termid":"MONDO:0003774"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"frontal convexity meningioma","secondary_identifiers":["NCIT:C5292","DOID:8000","MEDGEN:234272","UMLS:C1333643"],"termid":"MONDO:0004426","xrefs":{"Monarch":{"xref_id":"0004426"}}}


id: PBO:0075758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine and arginine repetitive matrix 1","termid":"PBO:0075758"}


id: PBO:0027022
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_punctate_nuclear_protein_localization","termid":"PBO:0027022"}


id: PBO:0042228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCNY antisense RNA 1","termid":"PBO:0042228"}


id: PR:P78825
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An adenosine kinase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04645","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosine kinase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC338.14","secondary_identifiers":["UniProtKB:P78825"],"synonyms":[{"name":"Spom972h-ADK","type":"exact"}],"termid":"PR:P78825"}


id: PBO:0075518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"speedy/RINGO cell cycle regulator family member A","termid":"PBO:0075518"}


id: GO:0022604
data:
  {"annotated_genes":["SJAG_04322","SJAG_04666","SJAG_01456","SJAG_00244","SJAG_04724","SJAG_00845","SJAG_04461","SJAG_00216","SJAG_02536","SJAG_01799","SJAG_00028","SJAG_03637","SJAG_02838","SJAG_00333","SJAG_00596","SJAG_02169","SJAG_04509","SJAG_03705","SJAG_02022","SJAG_00514","SJAG_02392","SJAG_04522","SJAG_00661","SJAG_00236","SJAG_03581","SJAG_03486","SJAG_00610"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[95639,94371,89652],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051519"},{"annotations":[99543,106653,110554,87844,117700,103283,116272],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051523"},{"annotations":[90519],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051517"},{"annotations":[116376,107409],"is_not":false,"rel_names":["is_a","positively_regulates","regulates"],"summary":null,"term":"GO:2000784"},{"annotations":[105158,93538,99978],"is_not":false,"rel_names":["regulates","positively_regulates","is_a"],"summary":null,"term":"GO:2000247"},{"annotations":[103494],"is_not":false,"rel_names":["regulates","positively_regulates","is_a"],"summary":null,"term":"GO:0061361"},{"annotations":[114841],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051516"},{"annotations":[119202,119203],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008360"},{"annotations":[95453,112839,90935,94377,118582,104330],"is_not":false,"rel_names":["is_a","regulates"],"summary":null,"term":"GO:2000100"},{"annotations":[102640,87690,92221],"is_not":false,"rel_names":["regulates","is_a"],"summary":null,"term":"GO:2000769"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.","definition_xrefs":["GOC:isa_complete"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of anatomical structure morphogenesis","termid":"GO:0022603"},{"relation_name":"regulates","term_name":"cell morphogenesis","termid":"GO:0000902"}],"gene_count":27,"genes_by_uniquename":{"SJAG_00028":null,"SJAG_00216":null,"SJAG_00236":null,"SJAG_00244":null,"SJAG_00333":null,"SJAG_00514":null,"SJAG_00596":null,"SJAG_00610":null,"SJAG_00661":null,"SJAG_00845":null,"SJAG_01456":null,"SJAG_01799":null,"SJAG_02022":null,"SJAG_02169":null,"SJAG_02392":null,"SJAG_02536":null,"SJAG_02838":null,"SJAG_03486":null,"SJAG_03581":null,"SJAG_03637":null,"SJAG_03705":null,"SJAG_04322":null,"SJAG_04461":null,"SJAG_04509":null,"SJAG_04522":null,"SJAG_04666":null,"SJAG_04724":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cell morphogenesis","references_by_uniquename":{"GO_REF:0000107":null,"PMID:30664646":null},"synonyms":[{"name":"negative regulation of cell shape and cell size","type":"related"},{"name":"positive regulation of cell shape and cell size","type":"related"},{"name":"regulation of cell shape and cell size","type":"related"}],"termid":"GO:0022604","terms_by_termid":{"GO:0008360":null,"GO:0051516":null,"GO:0051517":null,"GO:0051519":null,"GO:0051523":null,"GO:0061361":null,"GO:2000100":null,"GO:2000247":null,"GO:2000769":null,"GO:2000784":null}}


id: MONDO:0043193
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"richieri-costa guion-almeida cohen syndrome","secondary_identifiers":["UMLS:C2930979","MEDGEN:419687","MESH:C535676"],"synonyms":[{"name":"Richieri Costa Guion-Almeida dwarfism","type":"related"},{"name":"Richieri-costa Guion-Almeida Cohen syndrome","type":"exact"},{"name":"acrofacial dysostosis Richieri Costa Guion-Almeida type","type":"related"},{"name":"overgrowth - craniosynostosis - arthrogryposis","type":"related"}],"termid":"MONDO:0043193","xrefs":{"Monarch":{"xref_id":"0043193"}}}


id: GO:0005987
data:
  {"annotated_genes":["SJAG_04301"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76473],"is_not":false,"summary":null,"term":"GO:0005987"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sucrose metabolic process","termid":"GO:0005985"},{"relation_name":"is_a","term_name":"disaccharide catabolic process","termid":"GO:0046352"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04301":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"sucrose catabolic process","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"sucrose breakdown","type":"exact"},{"name":"sucrose catabolism","type":"exact"},{"name":"sucrose degradation","type":"exact"}],"termid":"GO:0005987","terms_by_termid":{"GO:0005987":null}}


id: GO:0102474
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose = 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity (obsolete GO:0102474)","termid":"GO:0102474"}


id: PBO:0001655
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IQGAP","termid":"PBO:0001655"}


id: PR:Q10479
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01860","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17C9.07","secondary_identifiers":["UniProtKB:Q10479"],"synonyms":[{"name":"Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-ALG8","type":"exact"},{"name":"asparagine-linked glycosylation protein 8 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10479"}


id: PATO:0001288
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of red and brown hue and low brightness.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"red brown","termid":"PATO:0001287"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dark red brown","termid":"PATO:0001288"}


id: PBO:0057709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1295b","termid":"PBO:0057709"}


id: PBO:0071859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S2 pseudogene 54","termid":"PBO:0071859"}


id: GO:0004558
data:
  {"annotated_genes":["SJAG_03824","SJAG_02131"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[101397,101398],"is_not":false,"summary":null,"term":"GO:0004558"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.","definition_xrefs":["EC:3.2.1.20"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-glucosidase activity","termid":"GO:0090599"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02131":null,"SJAG_03824":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016798"}],"interesting_parent_ids":["GO:0016798","GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"alpha-1,4-glucosidase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-191108","Reactome:R-HSA-191116","Reactome:R-HSA-5659899","MetaCyc:MALTODEXGLUCOSID-RXN","Reactome:R-HSA-191101","Reactome:R-HSA-5659861","Reactome:R-HSA-189053","Reactome:R-HSA-5659922","GO:0016982","Reactome:R-HSA-189102","Reactome:R-HSA-5659879","GO:0004562"],"synonyms":[{"name":"acid maltase activity","type":"related"},{"name":"alpha-D-glucosidase activity","type":"related"},{"name":"alpha-D-glucoside glucohydrolase activity","type":"related"},{"name":"alpha-glucopyranosidase activity","type":"related"},{"name":"alpha-glucoside hydrolase activity","type":"related"},{"name":"glucoinvertase activity","type":"related"},{"name":"glucosidoinvertase activity","type":"related"},{"name":"glucosidosucrase activity","type":"related"},{"name":"lysosomal alpha-glucosidase activity","type":"broad"},{"name":"maltase-glucoamylase activity","type":"related"}],"termid":"GO:0004558","terms_by_termid":{"GO:0004558":null}}


id: MONDO:0005725
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A protozoan infection that is caused by Cyclospora cayetanensis, which is most commonly acquired from contaminated food or water, and which is characterized by watery diarrhea and abdominal pain.","definition_xrefs":["NCIT:C128409"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coccidiosis","termid":"MONDO:0005707"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclosporiasis","secondary_identifiers":["ICD9:007.5","Orphanet:210","DOID:12750","MESH:D021866","SCTID:240372001","EFO:0007230","GARD:9528","ICD10CM:A07.4","SCTID:716860005","UMLS:C0343398","icd11.foundation:833744511","MEDGEN:91014","ICD10CM:A07.3"],"synonyms":[{"name":"Cyclospora caused disease or disorder","type":"exact"},{"name":"Cyclospora cayetanensis caused disease or disorder","type":"exact"},{"name":"Cyclospora cayetanensis disease or disorder","type":"exact"},{"name":"Cyclospora cayetanensis infectious disease","type":"exact"},{"name":"Cyclospora disease or disorder","type":"exact"},{"name":"Cyclospora infection","type":"related"},{"name":"Cyclospora infectious disease","type":"exact"},{"name":"cyclosporosis","type":"exact"},{"name":"infection of intestine caused by Cyclospora cayetanensis","type":"exact"},{"name":"intestinal infection caused by Cyclospora cayetanensis","type":"exact"}],"termid":"MONDO:0005725","xrefs":{"Monarch":{"xref_id":"0005725"}}}


id: FYPO:0003856
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to FR901464. Cells stop growing (and may die) at a concentration of FR901464 that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000139","FYPO:0000003","FYPO:0002683","FYPO:0001985"],"is_obsolete":false,"name":"sensitive to FR901464","synonyms":[{"name":"hypersensitive to FR901464","type":"exact"},{"name":"sensitive to FR901464 during mitotic cell cycle","type":"related"},{"name":"sensitive to FR901464 during vegetative growth","type":"exact"}],"termid":"FYPO:0003856"}


id: GO:0042771
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.","definition_xrefs":["GOC:mtg_apoptosis","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intrinsic apoptotic signaling pathway in response to DNA damage","termid":"GO:0008630"},{"relation_name":"is_a","term_name":"intrinsic apoptotic signaling pathway by p53 class mediator","termid":"GO:0072332"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","synonyms":[{"name":"DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis","type":"related"}],"termid":"GO:0042771"}


id: MONDO:0021019
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"X-linked recessive ocular albinism (XLOA) is a rare disorder characterized by ocular hypopigmentation, foveal hypoplasia, nystagmus, photodysphoria, and reduced visual acuity in males.","definition_xrefs":["Orphanet:54"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ocular albinism","termid":"MONDO:0017304"},{"relation_name":"is_a","term_name":"X-linked recessive disease","termid":"MONDO:0020605"},{"relation_name":"is_a","term_name":"albinism","termid":"MONDO:0043209"},{"relation_name":"is_a","term_name":"GPR143-related foveal hypoplasia","termid":"MONDO:0700230"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"X-linked recessive ocular albinism","secondary_identifiers":["SCTID:78642008","MEDGEN:90991","GARD:8471","MESH:C537863","NCIT:C118785","UMLS:C0342684","OMIM:300500","ICD9:270.2","icd11.foundation:846740259"],"synonyms":[{"name":"Nettleship-Falls syndrome","type":"exact"},{"name":"Nettleship-Falls type ocular albinism","type":"related"},{"name":"OA1","type":"exact"},{"name":"X-linked ocular albinism","type":"related"},{"name":"XLOA","type":"exact"},{"name":"albinism, ocular, type 1","type":"related"},{"name":"albinism, ocular, type I","type":"related"},{"name":"ocular albinism type 1","type":"exact"},{"name":"ocular albinism, Nettleship-Falls type","type":"exact"},{"name":"ocular albinism, type I, Nettleship-Falls type","type":"exact"}],"termid":"MONDO:0021019","xrefs":{"Monarch":{"xref_id":"0021019"}}}


id: PBO:0000922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA cleavage and polyadenylation specificity factor complex subunit Rna14 (predicted)","termid":"PBO:0000922"}


id: PBO:0055480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2913","termid":"PBO:0055480"}


id: PBO:0113436
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Spt4p/5p (DSIF) transcription elongation factor complex subunit; Spt4/5 binds ssRNA in a sequence-specific manner and along with RNAP I and II regulates transcriptional elongation, RNA processing, quality control, and transcription-coupled repair; localizes to kinetochores and heterochromatin, influencing chromosomal dynamics and silencing; required for transcription through long trinucleotide repeats in ORFs and non-protein coding regions; accelerates senescence through rDNA instability","termid":"PBO:0113436"}


id: FYPO:0003730
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing galactose as the carbon source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased cell population growth on galactose carbon source","termid":"FYPO:0000251"},{"relation_name":"is_a","term_name":"abolished vegetative cell population growth","termid":"FYPO:0001575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0002057","FYPO:0002060","FYPO:0000003","FYPO:0005447","FYPO:0002058","FYPO:0001985"],"is_obsolete":false,"name":"abolished cell population growth on galactose carbon source","synonyms":[{"name":"abolished galactose utilization","type":"related"},{"name":"abolished growth on galactose carbon source","type":"broad"},{"name":"abolished vegetative cell population growth on galactose carbon source","type":"exact"},{"name":"cell population growth on galactose carbon source abolished","type":"exact"}],"termid":"FYPO:0003730"}


id: MONDO:0007482
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Dyschondrosteosis - nephritis is characterized by the association of short stature due to mesomelic shortening of the limbs and Madelung deformity, with hereditary nephritis.","definition_xrefs":["Orphanet:1765"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dyschondrosteosis-nephritis syndrome","secondary_identifiers":["GARD:1994","OMIM:127350","MEDGEN:342135","UMLS:C1851986","MESH:C565080"],"synonyms":[{"name":"dyschondrosteosis and nephritis","type":"related"},{"name":"dyschondrosteosis nephritis","type":"related"},{"name":"mesomelic shortening and hereditary nephritis","type":"related"}],"termid":"MONDO:0007482","xrefs":{"Monarch":{"xref_id":"0007482"}}}


id: GO:0003215
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the right cardiac ventricle is generated and organized.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiac ventricle morphogenesis","termid":"GO:0003208"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac right ventricle morphogenesis","termid":"GO:0003215"}


id: GO:1903907
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization.","definition_xrefs":["GOC:TermGenie","PMID:23575248","GOC:als","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular component organization","termid":"GO:0051129"},{"relation_name":"is_a","term_name":"regulation of plasma membrane raft polarization","termid":"GO:1903906"},{"relation_name":"negatively_regulates","term_name":"plasma membrane raft polarization","termid":"GO:0044858"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0061024"],"is_obsolete":false,"name":"negative regulation of plasma membrane raft polarization","synonyms":[{"name":"down regulation of plasma membrane raft polarization","type":"exact"},{"name":"down-regulation of plasma membrane raft polarization","type":"exact"},{"name":"downregulation of plasma membrane raft polarization","type":"exact"},{"name":"inhibition of plasma membrane raft polarization","type":"narrow"}],"termid":"GO:1903907"}


id: MONDO:0958342
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare developmental defect during embryogenesis characterized by congenital absence of the optic nerve head, optic nerve fibers, retinal ganglion cells, and retinal blood vessels in a malformed eye. It often occurs unilaterally with otherwise normal brain development. In bilateral cases it is accompanied by other central nervous system malformations.","definition_xrefs":["Orphanet:637064"],"direct_ancestors":[{"relation_name":"is_a","term_name":"optic nerve disorder","termid":"MONDO:0002135"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"isolated optic nerve aplasia","secondary_identifiers":["UMLS:C5816782","MEDGEN:1836872"],"termid":"MONDO:0958342","xrefs":{"Monarch":{"xref_id":"0958342"}}}


id: MONDO:1012826
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ichthyosis that occurs in cattle due to a mutation in the ABCA12 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"ichthyosis, cattle","termid":"MONDO:1011541"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ichthyosis, ABCA12-related, cattle","secondary_identifiers":["OMIA:002238-9913"],"termid":"MONDO:1012826","xrefs":{"Monarch":{"xref_id":"1012826"}}}


id: PBO:0112852
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coilin, Mug174","termid":"PBO:0112852"}


id: GO:0062105
data:
  {"annotated_genes":["SJAG_00722","SJAG_03332","SJAG_01269","SJAG_01375","SJAG_02817","SJAG_03773"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[89416],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070039"},{"annotations":[75713,78434,75445],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008650"},{"annotations":[108914],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090486"},{"annotations":[97650,60240],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106050"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.","definition_xrefs":["PMID:30626973","RHEA:58956"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-methyltransferase activity","termid":"GO:0008171"},{"relation_name":"is_a","term_name":"RNA methyltransferase activity","termid":"GO:0008173"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00722":null,"SJAG_01269":null,"SJAG_01375":null,"SJAG_02817":null,"SJAG_03332":null,"SJAG_03773":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016740","GO:0016741","GO:0140098"],"is_obsolete":false,"name":"RNA 2'-O-methyltransferase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0062105","terms_by_termid":{"GO:0008650":null,"GO:0070039":null,"GO:0090486":null,"GO:0106050":null}}


id: GO:2000642
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of intracellular transport","termid":"GO:0032387"},{"relation_name":"is_a","term_name":"regulation of early endosome to late endosome transport","termid":"GO:2000641"},{"relation_name":"negatively_regulates","term_name":"early endosome to late endosome transport","termid":"GO:0045022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"negatively_regulates","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0008150","GO:0016192","GO:0006810"],"is_obsolete":false,"name":"negative regulation of early endosome to late endosome transport","termid":"GO:2000642"}


id: PBO:0067215
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 282, pseudogene","termid":"PBO:0067215"}


id: GO:0060315
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["GOC:BHF","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of release of sequestered calcium ion into cytosol","termid":"GO:0051280"},{"relation_name":"is_a","term_name":"regulation of ryanodine-sensitive calcium-release channel activity","termid":"GO:0060314"},{"relation_name":"is_a","term_name":"negative regulation of calcium ion transmembrane transporter activity","termid":"GO:1901020"},{"relation_name":"is_a","term_name":"negative regulation of cation channel activity","termid":"GO:2001258"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of ryanodine-sensitive calcium-release channel activity","termid":"GO:0060315"}


id: MONDO:0003962
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Froelich syndrome is characterized by obesity and hypogonadism due to a hypothalamic-pituitary disorder. The hypothalamus is a part of the brain where certain functions such as sleep cycles and body temperature are regulated. The pituitary is a gland that makes hormones that affect growth and the functions of other glands in the body. Froehlich syndrome is acquired(i.e., not thought to be inherited or genetic). This syndrome appears to affect males more commonly. The term 'Froelich syndrome' is rarely used today.","direct_ancestors":[{"relation_name":"is_a","term_name":"hypothalamic disorder","termid":"MONDO:0002150"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Froelich syndrome","secondary_identifiers":["MEDGEN:4795","DOID:6676","NCIT:C34625","ICD9:253.8","SCTID:62999006","UMLS:C0016724"],"synonyms":[{"name":"Adiposodysgenesis","type":"related"},{"name":"Babinski-Froelich syndrome","type":"exact"},{"name":"Froehlich syndrome","type":"exact"},{"name":"Froehlich's syndrome","type":"exact"},{"name":"Froelich's adiposity","type":"related"},{"name":"Froelich's syndrome","type":"exact"},{"name":"Frohlich syndrome","type":"exact"},{"name":"Frohlich's syndrome","type":"exact"},{"name":"Frolich's syndrome","type":"exact"},{"name":"Fröhlich syndrome","type":"exact"},{"name":"Launois-Cleret syndrome","type":"exact"},{"name":"adiposogenital dystrophy","type":"related"},{"name":"adiposogenital syndrome","type":"exact"},{"name":"dystrophia Adiposogenitalis","type":"exact"},{"name":"hypothalamic infantilism-obesity","type":"exact"},{"name":"sexual infantilism","type":"exact"}],"termid":"MONDO:0003962","xrefs":{"Monarch":{"xref_id":"0003962"}}}


id: GO:0010549
data:
  {"annotated_genes":["SJAG_00840","SJAG_00680"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[93634,103459],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905557"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of membrane disassembly.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular component organization","termid":"GO:0051128"},{"relation_name":"regulates","term_name":"membrane disassembly","termid":"GO:0030397"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00680":null,"SJAG_00840":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"regulation of membrane disassembly","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0010549","terms_by_termid":{"GO:1905557":null}}


id: GO:0061807
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.","definition_xrefs":["GOC:dph","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of DNA recombination","termid":"GO:0045911"},{"relation_name":"is_a","term_name":"regulation of DNA recombination at centromere","termid":"GO:0061806"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006259"},{"rel_name":"positively_regulates","termid":"GO:0006310"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006310"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0006310"],"is_obsolete":false,"name":"positive regulation of DNA recombination at centromere","synonyms":[{"name":"positive regulation of centromeric recombination","type":"exact"}],"termid":"GO:0061807"}


id: PBO:0038537
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"abhydrolase domain containing 12B","termid":"PBO:0038537"}


id: PBO:0056002
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 1","termid":"PBO:0056002"}


id: FYPO:0003663
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of RNA pyrophosphohydrolase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal catalytic activity","termid":"FYPO:0000661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000707","FYPO:0000654","FYPO:0000652","FYPO:0000661"],"is_obsolete":false,"name":"abnormal RNA pyrophosphohydrolase activity","termid":"FYPO:0003663"}


id: PBO:0033749
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-progressively_decreasing_vegetative_cell_population_growth_rate","termid":"PBO:0033749"}


id: PBO:0001451
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.1.26.4","termid":"PBO:0001451"}


id: GO:0042897
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other.","definition_xrefs":["ISBN:0198506732","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amide transmembrane transporter activity","termid":"GO:0042887"},{"relation_name":"is_a","term_name":"lipid transmembrane transporter activity","termid":"GO:0170055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"polymyxin transmembrane transporter activity","synonyms":[{"name":"polymyxin transporter activity","type":"related"}],"termid":"GO:0042897"}


id: MONDO:0018292
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete congenital disorder of glycosylation-related bone disorder (obsolete MONDO:0018292)","secondary_identifiers":["Orphanet:371195"],"synonyms":[{"name":"CDG-related bone disorder","type":"exact"}],"termid":"MONDO:0018292","xrefs":{"Monarch":{"xref_id":"0018292"}}}


id: PBO:0069487
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 754, pseudogene","termid":"PBO:0069487"}


id: PBO:0090627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SDA1 family protein","termid":"PBO:0090627"}


id: MONDO:0016677
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.","definition_xrefs":["MESH:D000014"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental defect during embryogenesis","termid":"MONDO:0019755"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"toxic or drug-related embryofetopathy","secondary_identifiers":["Orphanet:251529","MEDGEN:1843068","UMLS:C5680710","icd11.foundation:293076727"],"termid":"MONDO:0016677","xrefs":{"Monarch":{"xref_id":"0016677"}}}


id: PBO:0076990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"THAP domain containing 6","termid":"PBO:0076990"}


id: PBO:0081104
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger E-box binding homeobox 2 pseudogene 1","termid":"PBO:0081104"}


id: PBO:0075185
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear ribonucleoprotein polypeptide F pseudogene 2","termid":"PBO:0075185"}


id: PBO:0060279
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myosin heavy chain 13","termid":"PBO:0060279"}


id: PBO:0045832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 alpha 1 pseudogene 22","termid":"PBO:0045832"}


id: PBO:0027136
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-circularized_chromosome_during_mitotic_G2_phase","termid":"PBO:0027136"}


id: PR:Q9UT53
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC806.06c gene.","definition_xrefs":["UniProtKB:Q9UT53","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nicotinamide/nicotinic acid mononucleotide adenylyltransferase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC806.06c","synonyms":[{"name":"NMN adenylyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"NMN/NaMN adenylyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"NMNAT (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"NaMN adenylyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"NaMNAT (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-SPAC806.06c","type":"exact"},{"name":"nicotinamide-nucleotide adenylyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"nicotinate-nucleotide adenylyltransferase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UT53"}


id: PBO:0072866
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SAS-6 centriolar assembly protein","termid":"PBO:0072866"}


id: GO:0039576
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host JAK1 (Janus Kinase 1).","definition_xrefs":["PMID:16188985"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated suppression of host JAK-STAT cascade","termid":"GO:0039514"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity","secondary_identifiers":["GO:0039515","VZ:784"],"synonyms":[{"name":"disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity","type":"narrow"},{"name":"inhibition of host JAK activity by virus","type":"narrow"},{"name":"negative regulation by virus of host JAK","type":"narrow"},{"name":"negative regulation by virus of tyrosine phosphorylation of host STAT protein","type":"narrow"},{"name":"suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity","type":"narrow"},{"name":"suppression by virus of host JAK1 activity","type":"narrow"},{"name":"suppression by virus of tyrosine phosphorylation of host STAT protein","type":"narrow"},{"name":"viral inhibition of tyrosine phosphorylation of host STAT protein","type":"narrow"}],"termid":"GO:0039576"}


id: GO:0102794
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete cinnamaldehyde:oxygen oxidoreductase activity (obsolete GO:0102794)","termid":"GO:0102794"}


id: PBO:0058943
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIX23 pseudogene 2","termid":"PBO:0058943"}


id: PBO:0003310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Ppk19","termid":"PBO:0003310"}


id: GO:0007259
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cell surface receptor signaling pathway in which ligand binding causes the receptor to dimerize, bringing the receptor-associated JAKs into close proximity. The JAKs then phosphorylate and activate each other on tyrosine residues.This leads to the activation of associated STAT protein, causing the STATs to dissociate from the receptor, translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.","definition_xrefs":["PMID:12039028"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell surface receptor signaling pathway via STAT","termid":"GO:0097696"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"cell surface receptor signaling pathway via JAK-STAT","secondary_identifiers":["Wikipedia:JAK-STAT_signaling_pathway"],"synonyms":[{"name":"JAK-STAT cascade","type":"narrow"},{"name":"JAK-STAT signal transduction","type":"exact"},{"name":"receptor signaling pathway via JAK-STAT","type":"exact"}],"termid":"GO:0007259"}


id: FYPO:0005570
data:
  {"alleles_by_uniquename":{"SJAG_01143:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01143","name":"mid1delta","uniquename":"SJAG_01143:allele-1"},"SJAG_02392:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02392","name":"pom1delta","uniquename":"SJAG_02392:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"multi_locus_phenotype":[{"annotations":[119091],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0007177"}],"single_locus_phenotype":[{"annotations":[119110,119109],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000731"},{"annotations":[119081,119088,119092,119080],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0007177"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization during vegetative growth","termid":"FYPO:0000443"},{"relation_name":"is_a","term_name":"abnormal protein localization to cell periphery","termid":"FYPO:0006533"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01143":null,"SJAG_01665":null,"SJAG_02392":null,"SJAG_03596":null,"SJAG_03703":null,"SJAG_04498":null},"genotype_count":3,"genotypes_by_uniquename":{"mid1delta":{"display_name":"mid1delta","display_uniquename":"mid1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]}]},"mid1delta__pom1delta":{"display_name":"mid1delta pom1delta","display_uniquename":"mid1delta__pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]},"pom1delta":{"display_name":"pom1delta","display_uniquename":"pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"multi_locus_annotated_genes":["SJAG_01143","SJAG_02392"],"name":"abnormal protein localization to cell periphery during vegetative growth","references_by_uniquename":{"PMID:25866389":null},"single_locus_annotated_genes":["SJAG_02392","SJAG_01143"],"single_locus_genotype_uniquenames":["mid1delta","pom1delta"],"synonyms":[{"name":"abnormal protein localisation to cell periphery during vegetative growth","type":"exact"},{"name":"abnormal protein localization to cell periphery during mitotic cell cycle","type":"related"}],"termid":"FYPO:0005570","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000137":null,"FYPO:0000731":null,"FYPO:0007177":null,"FYPO_EXT:0000001":null}}


id: PBO:0110033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HSP90AB1 associated lncRNA 1","termid":"PBO:0110033"}


id: MONDO:1010768
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Vitiligo that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitiligo, non-human animal","termid":"MONDO:1010136"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vitiligo, cattle","secondary_identifiers":["OMIA:001055-9913"],"termid":"MONDO:1010768","xrefs":{"Monarch":{"xref_id":"1010768"}}}


id: PBO:0073496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small G protein signaling modulator 2","termid":"PBO:0073496"}


id: PR:O94662
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC651.04 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94662"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C651.04 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC651.04","synonyms":[{"name":"Spom972h-SPBC651.04","type":"exact"}],"termid":"PR:O94662"}


id: GO:0033946
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.","definition_xrefs":["EC:3.2.1.151"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-glucanase activity","termid":"GO:0052736"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016798"}],"interesting_parent_ids":["GO:0016798","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"xyloglucan-specific endo-beta-1,4-glucanase activity","secondary_identifiers":["MetaCyc:3.2.1.151-RXN"],"synonyms":[{"name":"1,4-beta-D-glucan glucanohydrolase activity","type":"broad"},{"name":"XEG","type":"related"},{"name":"XH","type":"related"},{"name":"[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity","type":"related"},{"name":"xyloglucan endo-beta-1,4-glucanase activity","type":"related"},{"name":"xyloglucanase activity","type":"related"},{"name":"xyloglucanendohydrolase activity","type":"related"}],"termid":"GO:0033946"}


id: PBO:0078562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 49B","termid":"PBO:0078562"}


id: PBO:0068751
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U5E small nuclear 6, pseudogene","termid":"PBO:0068751"}


id: GO:0052885
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + all-trans-retinyl ester = 11-cis-retinol + fatty acid.","definition_xrefs":["RHEA:31771"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674","GO:0016788"],"is_obsolete":false,"name":"all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity","secondary_identifiers":["KEGG_REACTION:R08388","MetaCyc:RXN-12550"],"synonyms":[{"name":"all-trans-retinol isomerase:hydrolase activity","type":"broad"},{"name":"all-trans-retinyl ester acylhydrolase, 11-cis retinol forming activity","type":"related"},{"name":"all-trans-retinylester 11-cis isomerohydrolase activity","type":"related"},{"name":"retinoid isomerohydrolase activity","type":"broad"},{"name":"retinol isomerase activity","type":"broad"}],"termid":"GO:0052885"}


id: PBO:0042748
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centromere protein U pseudogene 1","termid":"PBO:0042748"}


id: GO:0015707
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inorganic anion transport","termid":"GO:0015698"},{"relation_name":"is_a","term_name":"nitrogen compound transport","termid":"GO:0071705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"nitrite transport","termid":"GO:0015707"}


id: PBO:0065103
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRKAR2A antisense RNA 1","termid":"PBO:0065103"}


id: GO:0036449
data:
  {"annotated_genes":["SJAG_04841","SJAG_01613","SJAG_02761"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[99014,100170],"is_not":false,"summary":null,"term":"GO:0036449"},{"annotations":[97066],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0062194"}]},"cv_name":"cellular_component","definition":"The end of a microtubule that does not preferentially grow (polymerize).","definition_xrefs":["GOC:lb","PMID:23169647"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule end","termid":"GO:1990752"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01613":null,"SJAG_02761":null,"SJAG_04841":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0015630"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0015630","GO:0005575"],"is_obsolete":false,"name":"microtubule minus-end","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"microtubule minus end","type":"exact"}],"termid":"GO:0036449","terms_by_termid":{"GO:0036449":null,"GO:0062194":null}}


id: MONDO:0030619
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"retinitis pigmentosa","termid":"MONDO:0019200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"retinitis pigmentosa 92","secondary_identifiers":["UMLS:C5562022","OMIM:619614","MEDGEN:1794232"],"synonyms":[{"name":"RP92","type":"exact"},{"name":"retinitis pigmentosa 92","type":"exact"}],"termid":"MONDO:0030619","xrefs":{"Monarch":{"xref_id":"0030619"}}}


id: PR:Q9UTH3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppk6 gene.","definition_xrefs":["UniProtKB:Q9UTH3","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine-protein kinase ppk6 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1805.01c","synonyms":[{"name":"Spom972h-ppk6","type":"exact"}],"termid":"PR:Q9UTH3"}


id: GO:0052589
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.","definition_xrefs":["MetaCyc:RXNI-3"],"gene_count":0,"genotype_count":0,"name":"obsolete malate dehydrogenase (menaquinone) activity (obsolete GO:0052589)","termid":"GO:0052589"}


id: MONDO:0033372
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0005027"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 63","secondary_identifiers":["UMLS:C4693810","MEDGEN:1646846","DOID:0080426","OMIM:617976"],"synonyms":[{"name":"DEE63","type":"exact"},{"name":"EIEE63","type":"exact"},{"name":"developmental and epileptic encephalopathy 63","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 63","type":"exact"}],"termid":"MONDO:0033372","xrefs":{"Monarch":{"xref_id":"0033372"}}}


id: PBO:0088509
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol phosphorylceramide synthase Aur1","termid":"PBO:0088509"}


id: GO:0046044
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine ribonucleoside monophosphate metabolic process","termid":"GO:0009173"},{"relation_name":"is_a","term_name":"pyrimidine ribonucleotide metabolic process","termid":"GO:0009218"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"TMP metabolic process","synonyms":[{"name":"TMP metabolism","type":"exact"}],"termid":"GO:0046044"}


id: GO:2000257
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein activation cascade.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein maturation","termid":"GO:1903317"},{"relation_name":"regulates","term_name":"protein activation cascade","termid":"GO:0072376"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0051604"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0051604","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of protein activation cascade","synonyms":[{"name":"regulation of protein activation pathway","type":"exact"},{"name":"regulation of protein activitory cascade","type":"exact"}],"termid":"GO:2000257"}


id: PBO:0028060
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_rate_of_DNA_replication_during_vegetative_growth","termid":"PBO:0028060"}


id: GO:0035647
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H+ = a 5-beta-3-oxo-steroid + NADP+.","definition_xrefs":["PMID:19166903","GOC:kad","MetaCyc:RXN-9726"],"gene_count":0,"genotype_count":0,"name":"obsolete 3-oxo-delta(4,5)-steroid 5-beta-reductase activity (obsolete GO:0035647)","synonyms":[{"name":"3-oxo-delta4,5-steroid 5beta-reductase","type":"exact"}],"termid":"GO:0035647"}


id: PBO:0072893
data:
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id: PR:Q9HE09
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id: PBO:0000683
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id: GO:1903564
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id: GO:0010157
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id: GO:0002660
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id: GO:0036027
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id: MONDO:0008424
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id: GO:0140098
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id: MONDO:0017548
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id: GO:0060294
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id: GO:1902821
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id: PBO:0077904
data:
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id: PBO:0017039
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id: MONDO:0012530
data:
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id: GO:1990758
data:
  {"annotated_genes":["SJAG_01601","SJAG_05220","SJAG_01224","SJAG_04076","SJAG_05266","SJAG_00930","SJAG_00335","SJAG_02731","SJAG_03543","SJAG_04623","SJAG_04140","SJAG_04412","SJAG_01805","SJAG_05319","SJAG_00918","SJAG_03989","SJAG_01297","SJAG_02451","SJAG_00082","SJAG_00678","SJAG_00302","SJAG_01371","SJAG_04259","SJAG_01837","SJAG_03048","SJAG_01082","SJAG_01775","SJAG_01211","SJAG_03437","SJAG_02336"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[77732,88929,89149,89533,90774,93628,93993,98424,98927,100323,102232,103338,103690,107300,108055,108681,109685,112412,112413,112414,113020,113886,114290,116710,118486],"is_not":false,"summary":null,"term":"GO:1990758"},{"annotations":[110996,116470,89789,102177,93602],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0140429"}]},"cv_name":"biological_process","definition":"The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.","definition_xrefs":["PMID:15309047","PMID:26258632","PMID:26705896"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sister chromatid biorientation","termid":"GO:0031134"},{"relation_name":"is_a","term_name":"attachment of mitotic spindle microtubules to kinetochore","termid":"GO:0051315"}],"gene_count":30,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_00302":null,"SJAG_00335":null,"SJAG_00678":null,"SJAG_00918":null,"SJAG_00930":null,"SJAG_01082":null,"SJAG_01211":null,"SJAG_01224":null,"SJAG_01297":null,"SJAG_01371":null,"SJAG_01601":null,"SJAG_01775":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_02336":null,"SJAG_02451":null,"SJAG_02731":null,"SJAG_03048":null,"SJAG_03437":null,"SJAG_03543":null,"SJAG_03989":null,"SJAG_04076":null,"SJAG_04140":null,"SJAG_04259":null,"SJAG_04412":null,"SJAG_04623":null,"SJAG_05220":null,"SJAG_05266":null,"SJAG_05319":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0000070"}],"interesting_parent_ids":["GO:0000070","GO:0008150","GO:0007049"],"is_obsolete":false,"name":"mitotic sister chromatid biorientation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:1990758","terms_by_termid":{"GO:0140429":null,"GO:1990758":null}}


id: PBO:0059712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO2 pseudogene 20","termid":"PBO:0059712"}


id: MONDO:1010258
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Glomerulonephritis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nephritis, non-human animal","termid":"MONDO:1010259"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glomerulonephritis, non-human animal","secondary_identifiers":["OMIA:000413"],"termid":"MONDO:1010258","xrefs":{"Monarch":{"xref_id":"1010258"}}}


id: PR:Q9Y811
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pth3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9Y811"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized peptide chain release factor-like protein C1105.18c, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1105.18c","synonyms":[{"name":"Spom972h-pth3","type":"exact"}],"termid":"PR:Q9Y811"}


id: PBO:0081453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 320","termid":"PBO:0081453"}


id: MONDO:0015894
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Any of the forms of hyperthyroidism that have a rare incidence.","definition_xrefs":["MONDO:patterns/rare"],"gene_count":0,"genotype_count":0,"name":"obsolete rare hyperthyroidism (obsolete MONDO:0015894)","secondary_identifiers":["Orphanet:181399"],"synonyms":[{"name":"rare hyperthyroidism","type":"exact"}],"termid":"MONDO:0015894","xrefs":{"Monarch":{"xref_id":"0015894"}}}


id: GO:0097721
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle.","definition_xrefs":["GOC:cilia","PMID:25686250","PMID:13978319"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic vesicle","termid":"GO:0031410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0031410","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"ciliary vesicle","synonyms":[{"name":"CV","type":"related"},{"name":"primary ciliary vesicle","type":"exact"}],"termid":"GO:0097721"}


id: PBO:0057644
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1236","termid":"PBO:0057644"}


id: PBO:0004492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidate cytidylyltransferase (predicted)","termid":"PBO:0004492"}


id: GO:0033678
data:
  {"annotated_genes":["SJAG_02242","SJAG_03780"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[99689,112317],"is_not":false,"summary":null,"term":"GO:0033678"}]},"cv_name":"molecular_function","definition":"Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA/RNA helicase activity","termid":"GO:0033677"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02242":null,"SJAG_03780":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140097"}],"interesting_parent_ids":["GO:0003824","GO:0140098","GO:0016853","GO:0003674","GO:0140097"],"is_obsolete":false,"name":"5'-3' DNA/RNA helicase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0033682","Reactome:R-HSA-163120"],"synonyms":[{"name":"5' to 3' DNA/RNA helicase activity","type":"exact"},{"name":"ATP-dependent 5' to 3' DNA/RNA helicase activity","type":"exact"},{"name":"ATP-dependent 5'-3' DNA/RNA helicase activity","type":"exact"}],"termid":"GO:0033678","terms_by_termid":{"GO:0033678":null}}


id: MONDO:0000899
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete malignant epithelioid hemangioendothelioma (obsolete MONDO:0000899)","termid":"MONDO:0000899","xrefs":{"Monarch":{"xref_id":"0000899"}}}


id: MONDO:0009040
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"craniosynostosis-intellectual disability syndrome of 51N and Gettig","secondary_identifiers":["MEDGEN:341781","OMIM:218649","UMLS:C1857473","MESH:C565664"],"synonyms":[{"name":"Lin-Gettig syndrome","type":"related"},{"name":"craniosynostosis-intellectual disability syndrome of Lin and Gettig","type":"related"},{"name":"craniosynostosis-mental retardation syndrome of Lin and Gettig","type":"related"}],"termid":"MONDO:0009040","xrefs":{"Monarch":{"xref_id":"0009040"}}}


id: PBO:0061904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"opiorphin prepropeptide","termid":"PBO:0061904"}


id: PBO:0041236
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 1 open reading frame 87","termid":"PBO:0041236"}


id: MONDO:0957268
data:
  {"annotated_genes":["SJAG_02463","SJAG_01941"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86366,86367],"is_not":false,"summary":null,"term":"MONDO:0957268"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01941":null,"SJAG_02463":null},"genotype_count":0,"is_obsolete":false,"name":"hypersulfaturia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5830511","MEDGEN:1841147","OMIM:620372"],"termid":"MONDO:0957268","terms_by_termid":{"MONDO:0957268":null},"xrefs":{"Monarch":{"xref_id":"0957268"}}}


id: MONDO:0002835
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete papillary transitional carcinoma (obsolete MONDO:0002835)","termid":"MONDO:0002835","xrefs":{"Monarch":{"xref_id":"0002835"}}}


id: GO:0002180
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.","definition_xrefs":["PMID:19075240"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"},{"relation_name":"is_a","term_name":"oxidoreductase complex","termid":"GO:1990204"},{"relation_name":"part_of","term_name":"nuclear membrane","termid":"GO:0031965"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005634"],"is_obsolete":false,"name":"5-lipoxygenase complex","termid":"GO:0002180"}


id: PBO:0002614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cornichon family protein Erv14 (predicted)","termid":"PBO:0002614"}


id: PBO:0072606
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal L24 domain containing 1 pseudogene 1","termid":"PBO:0072606"}


id: PBO:0110198
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial tRNA (guanine-N2-)-methyltransferase Trm1.1","termid":"PBO:0110198"}


id: MONDO:1012759
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Junctional epidermolysis bullosa that occurs in sheep due to a mutation in the ITGB4 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"junctionalis epidermolysis bullosa , non-human animal","termid":"MONDO:1011426"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"junctional epidermolysis bullosa, ITGB4-related, sheep","secondary_identifiers":["OMIA:001948-9940"],"synonyms":[{"name":"epidermolysis bullosa, junctionalis, ITGB4-related, sheep","type":"exact"}],"termid":"MONDO:1012759","xrefs":{"Monarch":{"xref_id":"1012759"}}}


id: GO:0097666
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).","definition_xrefs":["PMID:9499404","GOC:jd","GOC:vw","PMID:15147268"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SCF ubiquitin ligase complex","termid":"GO:0019005"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"SCF-Met30/Pof1 ubiquitin ligase complex","termid":"GO:0097666"}


id: PBO:0084763
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial mRNA maturase; forms a complex with Mrs1p to mediate splicing of the bI3 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA","termid":"PBO:0084763"}


id: FYPO:0004133
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal level of substance in cell","termid":"FYPO:0001076"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal reactive oxygen species level during nitrogen starvation","synonyms":[{"name":"normal ROS accumulation during nitrogen starvation","type":"related"},{"name":"normal ROS level during nitrogen starvation","type":"exact"},{"name":"normal cellular reactive oxygen species level during nitrogen starvation","type":"exact"},{"name":"normal reactive oxygen species level during nitrogen depletion","type":"exact"},{"name":"normal reactive oxygen species level during nitrogen deprivation","type":"exact"}],"termid":"FYPO:0004133"}


id: GO:0042630
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in the behavior of an organism as a result of deprivation of water.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavior","termid":"GO:0007610"},{"relation_name":"part_of","term_name":"response to water deprivation","termid":"GO:0009414"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"behavioral response to water deprivation","synonyms":[{"name":"behavioral response to drought","type":"exact"},{"name":"behavioral response to thirst","type":"exact"},{"name":"behavioural response to water deprivation","type":"exact"}],"termid":"GO:0042630"}


id: PBO:0044322
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CYCS pseudogene 2","termid":"PBO:0044322"}


id: GO:0001099
data:
  {"annotated_genes":["SJAG_03118","SJAG_00095","SJAG_00159","SJAG_00139","SJAG_04353","SJAG_01151","SJAG_04933","SJAG_00483","SJAG_01610","SJAG_00448"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[64940],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0099122"},{"annotations":[77880,72281],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990269"},{"annotations":[78472,70752,72093,76200,78462],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000993"},{"annotations":[79031],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001096"},{"annotations":[76052],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001097"}]},"cv_name":"molecular_function","definition":"Binding to a component of the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.","definition_xrefs":["GOC:txnOH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"basal transcription machinery binding","termid":"GO:0001098"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00095":null,"SJAG_00139":null,"SJAG_00159":null,"SJAG_00448":null,"SJAG_00483":null,"SJAG_01151":null,"SJAG_01610":null,"SJAG_03118":null,"SJAG_04353":null,"SJAG_04933":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"basal RNA polymerase II transcription machinery binding","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"synonyms":[{"name":"basal RNAP II transcription machinery binding","type":"exact"}],"termid":"GO:0001099","terms_by_termid":{"GO:0000993":null,"GO:0001096":null,"GO:0001097":null,"GO:0099122":null,"GO:1990269":null}}


id: MONDO:0017574
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chronic intestinal pseudo-obstruction (CIPO) is a rare gastrointestinal motility disorder characterized by recurring episodes resembling mechanical obstruction in the absence of organic, systemic, or metabolic disorders, and without any physical obstruction being detected by X-ray or during surgery. CIPO develops predominantly in children and may be present at birth.","definition_xrefs":["Orphanet:2978"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal pseudo-obstruction","termid":"MONDO:0002803"},{"relation_name":"is_a","term_name":"intestinal motility disease","termid":"MONDO:0021189"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"chronic intestinal pseudoobstruction","secondary_identifiers":["GARD:12744","MEDGEN:536759","NANDO:2200946","NORD:970","UMLS:C0238062","NANDO:1200458","SCTID:235828008"],"synonyms":[{"name":"CIPO","type":"exact"},{"name":"Chronic Intestinal Pseudo-Obstruction","type":"exact"},{"name":"chronic intestinal pseudo-obstruction","type":"exact"},{"name":"cipo","type":"exact"},{"name":"intestinal pseudo-obstruction, chronic","type":"exact"}],"termid":"MONDO:0017574","xrefs":{"Monarch":{"xref_id":"0017574"}}}


id: GO:0004672
data:
  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id: MONDO:0700127
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Trisomy 21 characterized by the presence of an extra chromosome 21 in some of the cells of the organism.","definition_xrefs":["PMID:29218069"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trisomy 21","termid":"MONDO:0700126"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mosaic trisomy 21","secondary_identifiers":["MEDGEN:419386","UMLS:C2931324"],"termid":"MONDO:0700127","xrefs":{"Monarch":{"xref_id":"0700127"}}}


id: MONDO:0029811
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete laminopathy with peripheral neuropathy (obsolete MONDO:0029811)","secondary_identifiers":["Orphanet:300758"],"termid":"MONDO:0029811","xrefs":{"Monarch":{"xref_id":"0029811"}}}


id: GO:1904403
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.","definition_xrefs":["GOC:TermGenie","PMID:17822405","GO_REF:0000071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to ketone","termid":"GO:1901655"},{"relation_name":"is_a","term_name":"cellular response to nitrogen compound","termid":"GO:1901699"},{"relation_name":"is_a","term_name":"response to nocodazole","termid":"GO:1904402"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to nocodazole","termid":"GO:1904403"}


id: MONDO:0008620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"This syndrome is an isolated upper limb mesomelic dysplasia. It has been described in four patients from two unrelated families (a man and his daughter, and a Lebanese man and his son). Patients present with ulnar hypoplasia with severe radial bowing, but normal stature. The mode of transmission is likely to be autosomal dominant with variable expressivity.","definition_xrefs":["Orphanet:2497"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"},{"relation_name":"is_a","term_name":"mesomelic dysplasia","termid":"MONDO:0023599"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"upper limb mesomelic dysplasia","secondary_identifiers":["UMLS:C5574958","icd11.foundation:2013121778","MESH:C538069","OMIM:191440","GARD:2408","MEDGEN:1811806"],"synonyms":[{"name":"Fryns Hofkens Fabry syndrome","type":"related"},{"name":"Fryns-Hofkens-Fabry syndrome","type":"exact"},{"name":"ulna hypoplasia","type":"related"},{"name":"ulnar hypoplasia","type":"related"},{"name":"upper limb mesomelic dysplasia","type":"exact"}],"termid":"MONDO:0008620","xrefs":{"Monarch":{"xref_id":"0008620"}}}


id: PBO:0028242
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-viable_swollen_vacuolated_spheroid_vegetative_cell","termid":"PBO:0028242"}


id: PBO:0110829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-binding transcription factor, amino acid sensing, Cha4","termid":"PBO:0110829"}


id: MONDO:0019350
data:
  {"annotated_genes":["SJAG_01183"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85270],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012981"}]},"cv_name":"mondo","definition":"Hereditary spherocytosis is a congenital hemolytic anemia with a wide clinical spectrum (from symptom-free carriers to severe hemolysis) characterized by anemia, variable jaundice, splenomegaly and cholelithiasis.","definition_xrefs":["Orphanet:822"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hemolytic anemia","termid":"MONDO:0003689"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01183":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"hereditary spherocytosis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NORD:777","GARD:6639","ICD10CM:D58.0","NANDO:2200622","icd11.foundation:1305248013","ICD9:282.0","DOID:12971","NCIT:C97074","MEDGEN:52450","SCTID:55995005","MedDRA:10019904","MESH:D013103","UMLS:C0037889"],"synonyms":[{"name":"Minkowski Chauffard syndrome","type":"exact"},{"name":"Minkowski-Chauffard disease","type":"exact"},{"name":"congenital spherocytic hemolytic anaemia","type":"exact"},{"name":"congenital spherocytic hemolytic anemia","type":"exact"},{"name":"congenital spherocytosis","type":"related"},{"name":"hereditary spherocytosis","type":"exact"},{"name":"spherocytic anaemia","type":"exact"},{"name":"spherocytic anemia","type":"exact"}],"termid":"MONDO:0019350","terms_by_termid":{"MONDO:0012981":null},"xrefs":{"Monarch":{"xref_id":"0019350"}}}


id: PBO:0090806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centromeric adaptor, shugoshin Sgo2","termid":"PBO:0090806"}


id: GO:0034003
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene.","definition_xrefs":["EC:4.2.3.21","RHEA:10340"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sesquiterpene synthase activity","termid":"GO:0010334"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"vetispiradiene synthase activity","secondary_identifiers":["KEGG_REACTION:R06523","MetaCyc:RXN-4823"],"synonyms":[{"name":"HVS","type":"related"},{"name":"pemnaspirodiene synthase activity","type":"related"},{"name":"trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity","type":"related"},{"name":"vetispiradiene cyclase activity","type":"related"},{"name":"vetispiradiene-forming farnesyl pyrophosphate cyclase activity","type":"related"}],"termid":"GO:0034003"}


id: GO:0005114
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type II transforming growth factor beta receptor.","definition_xrefs":["GOC:mah","PMID:11252892","GOC:ceb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transforming growth factor beta receptor binding","termid":"GO:0005160"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"type II transforming growth factor beta receptor binding","synonyms":[{"name":"TGF-beta type II binding","type":"exact"},{"name":"punt binding","type":"narrow"},{"name":"punt ligand","type":"narrow"},{"name":"transforming growth factor beta ligand binding to type II receptor","type":"related"},{"name":"transforming growth factor beta receptor type II binding","type":"exact"},{"name":"type II TGF-beta binding","type":"exact"}],"termid":"GO:0005114"}


id: GO:1900536
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of glucose homeostasis.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of glucose homeostasis (obsolete GO:1900536)","synonyms":[{"name":"regulation of glucose homeostasis","type":"exact"}],"termid":"GO:1900536"}


id: GO:0006977
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (obsolete GO:0006977)","secondary_identifiers":["Reactome:R-HSA-69563","Reactome:R-HSA-6791312"],"synonyms":[{"name":"positive regulation of cell cycle arrest by p53-mediated DNA damage response","type":"exact"}],"termid":"GO:0006977"}


id: PBO:0091133
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase assembly protein Cox20","termid":"PBO:0091133"}


id: GO:0009406
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete virulence (obsolete GO:0009406)","synonyms":[{"name":"virulence","type":"exact"}],"termid":"GO:0009406"}


id: PR:000085726
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A histone H3.1, initiator methionine removed form (Schizosaccharomyces pombe) that has been methylated on Lys-9 and phosphorylated on Ser-10. Example: UniProtKB:P09988, 2-136, Lys-10, MOD:00663|Ser-11, MOD:00046.","definition_xrefs":["PRO:DAN","PomBase:VW","PMID:19362535"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H3.1, initiator methionine removed form (Schizosaccharomyces pombe)","termid":"PR:000027574"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hht1/Me(K9),Phos(S10)","pombase_gene_id":"SPAC1834.04","synonyms":[{"name":"PRO_0000221366, Lys-10, MOD:00663|Ser-11, MOD:00046","type":"related"},{"name":"PomBase_original_PRO_term_name: histone H3.1, initiator methionine removed K9-methylated and phosphorylated 1 (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-hht1/InitMet-/K9MePhos:1","type":"exact"},{"name":"UniProtKB:P09988, 2-136, Lys-10, MOD:00663|Ser-11, MOD:00046","type":"related"},{"name":"hht1/Me(K9),Phos(S10)","type":"exact"}],"termid":"PR:000085726"}


id: GO:0042667
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron fate specification","termid":"GO:0048665"},{"relation_name":"part_of","term_name":"auditory receptor cell fate commitment","termid":"GO:0009912"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"auditory receptor cell fate specification","synonyms":[{"name":"auditory hair cell fate specification","type":"exact"}],"termid":"GO:0042667"}


id: PBO:0069050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 296, pseudogene","termid":"PBO:0069050"}


id: GO:0004966
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with galanin to initiate a change in cell activity.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuropeptide receptor activity","termid":"GO:0008188"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"galanin receptor activity","termid":"GO:0004966"}


id: PBO:0044565
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DAZ associated protein 2","termid":"PBO:0044565"}


id: GO:0044681
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.","definition_xrefs":["PMID:10940029","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"sulfopyruvate decarboxylase complex","termid":"GO:0044681"}


id: PBO:0077344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 86A","termid":"PBO:0077344"}


id: MONDO:0019631
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A developmental ocular anomaly in which the primary vitreous body and its surrounding hyaloid vasculature failed to regress. It is usually unilateral and characterized by cataract; microphthalmos (small eyeballs), and retrolenticular fibrovascular tissue. (from Yanoff: Ophthalmology, 2nd ed.)","definition_xrefs":["MESH:D054514"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitreous disorder","termid":"MONDO:0004860"},{"relation_name":"is_a","term_name":"congenital vitreoretinal dysplasia","termid":"MONDO:0020247"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0002320"],"is_obsolete":false,"name":"persistent hyperplastic primary vitreous","secondary_identifiers":["GARD:16803","icd11.foundation:1011137326","UMLS:C0266568","Orphanet:91495","NCIT:C161554","MEDGEN:120583","SCTID:314270008","DOID:0060282","OMIMPS:221900"],"synonyms":[{"name":"PFVS","type":"exact"},{"name":"PHPV","type":"exact"},{"name":"congenital retinal detachment","type":"exact"},{"name":"ncRNA disease","type":"exact"},{"name":"non-syndromic congenital retinal non-attachment","type":"exact"},{"name":"persistent fetal vasculature syndrome","type":"exact"},{"name":"persistent foetal vasculature syndrome","type":"exact"}],"termid":"MONDO:0019631","xrefs":{"Monarch":{"xref_id":"0019631"}}}


id: PBO:0043162
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell death inducing DFFA like effector b","termid":"PBO:0043162"}


id: GO:2000837
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of androstenedione secretion.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lipid transport","termid":"GO:0032368"},{"relation_name":"is_a","term_name":"regulation of hormone secretion","termid":"GO:0046883"},{"relation_name":"regulates","term_name":"androstenedione secretion","termid":"GO:0035941"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0023052","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of androstenedione secretion","synonyms":[{"name":"regulation of androst-4-ene-3,17-dione secretion","type":"exact"}],"termid":"GO:2000837"}


id: PBO:0089728
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell wall beta-glucosidase Psu2","termid":"PBO:0089728"}


id: GO:2000333
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"negative regulation of cellular component organization","termid":"GO:0051129"},{"relation_name":"is_a","term_name":"regulation of blood microparticle formation","termid":"GO:2000332"},{"relation_name":"negatively_regulates","term_name":"blood microparticle formation","termid":"GO:0072564"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of blood microparticle formation","synonyms":[{"name":"negative regulation of microparticle generation","type":"exact"},{"name":"negative regulation of microparticle release","type":"exact"}],"termid":"GO:2000333"}


id: GO:2000454
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of CD8-positive, alpha-beta T cell extravasation","termid":"GO:2000451"},{"relation_name":"is_a","term_name":"regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation","termid":"GO:2000452"},{"relation_name":"positively_regulates","term_name":"CD8-positive, alpha-beta cytotoxic T cell extravasation","termid":"GO:0035698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation","termid":"GO:2000454"}


id: PBO:0060203
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mucin like 1","termid":"PBO:0060203"}


id: PBO:0050603
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydroxysteroid 11-beta dehydrogenase 1 like","termid":"PBO:0050603"}


id: GO:0002229
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.","definition_xrefs":["GOC:add","PMID:16497589"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to oomycetes","termid":"GO:0002239"},{"relation_name":"is_a","term_name":"defense response to other organism","termid":"GO:0098542"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"defense response to oomycetes","termid":"GO:0002229"}


id: GO:0051636
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binding to a component on the surface of a Gram-negative bacterial cell.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete Gram-negative bacterial cell surface binding (obsolete GO:0051636)","synonyms":[{"name":"Gram-negative bacterial binding","type":"exact"},{"name":"Gram-negative bacterial cell surface binding","type":"exact"},{"name":"Gram-negative bacterium binding","type":"exact"},{"name":"Gram-negative bacterium cell surface binding","type":"exact"},{"name":"binding to Gram-negative bacterium","type":"exact"}],"termid":"GO:0051636"}


id: PBO:0043821
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coproporphyrinogen oxidase","termid":"PBO:0043821"}


id: FYPO:0001945
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein transport during vegetative growth","termid":"FYPO:0004848"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001312","FYPO:0000257","FYPO:0000138"],"is_obsolete":false,"name":"normal protein secretion","synonyms":[{"name":"normal protein secretion during mitotic cell cycle","type":"related"},{"name":"normal protein secretion during vegetative growth","type":"exact"}],"termid":"FYPO:0001945"}


id: PR:Q10448
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC12B10.15c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10448"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C12B10.15c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC12B10.15c","synonyms":[{"name":"Spom972h-SPAC12B10.15c","type":"exact"}],"termid":"PR:Q10448"}


id: PBO:0076652
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T-box transcription factor 6","termid":"PBO:0076652"}


id: PR:Q9Y7N2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rox3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9Y7N2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator of RNA polymerase II transcription subunit 19 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1450.05c","synonyms":[{"name":"RNA polymerase II mediator complex protein rox3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-rox3","type":"exact"},{"name":"mediator complex subunit 19 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9Y7N2"}


id: MONDO:0018476
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"combined dystonia","termid":"MONDO:0020065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"dystonia-aphonia syndrome","secondary_identifiers":["Orphanet:412217","GARD:21739","MEDGEN:1675660","UMLS:C5190573"],"termid":"MONDO:0018476","xrefs":{"Monarch":{"xref_id":"0018476"}}}


id: GO:0102830
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 stachyose = verbascose + raffinose.","definition_xrefs":["GOC:pz","PMID:12060258"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexosyltransferase activity","termid":"GO:0016758"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0016757"],"is_obsolete":false,"name":"verbascose synthase activity","secondary_identifiers":["MetaCyc:RXN-8286"],"termid":"GO:0102830"}


id: GO:0061126
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of positive chemotaxis to cAMP by DIF-1","termid":"GO:0061120"},{"relation_name":"is_a","term_name":"positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone","termid":"GO:0061124"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of positive chemotaxis to cAMP by DIF-1","termid":"GO:0061126"}


id: MONDO:0019654
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial idiopathic steroid-resistant nephrotic syndrome","termid":"MONDO:0019006"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis","secondary_identifiers":["NANDO:2200111","Orphanet:93217"],"termid":"MONDO:0019654","xrefs":{"Monarch":{"xref_id":"0019654"}}}


id: GO:0033665
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.","definition_xrefs":["GOC:tb","GOC:dph","GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of growth or development of symbiont in host (obsolete GO:0033665)","synonyms":[{"name":"modulation of growth or development of organism within host","type":"exact"},{"name":"modulation of growth or development of symbiont within host","type":"exact"},{"name":"modulation of invasive growth","type":"broad"},{"name":"regulation of growth or development of symbiont in host","type":"exact"},{"name":"regulation of growth or development of symbiont within host","type":"exact"}],"termid":"GO:0033665"}


id: MOD:00116
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-cysteine residue to S-diacylglycerol-L-cysteine.","definition_xrefs":["RESID:AA0107","PubMed:10896212","PubMed:9056182","Unimod:377#C","PubMed:4575979"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"},{"relation_name":"is_a","term_name":"lipoconjugated residue","termid":"MOD:01155"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"},{"rel_name":"is_a","termid":"MOD:01155"}],"interesting_parent_ids":["MOD:01155","MOD:00905"],"is_obsolete":false,"name":"S-diacylglycerol-L-cysteine","synonyms":[{"name":"(2R)-2-amino-3-[(2S)-2-((9Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]sulfanylpropanoic acid","type":"exact"},{"name":"2-amino-3-[(S)-2-((Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]thiopropanoic acid","type":"exact"},{"name":"Diacylglycerol","type":"related"},{"name":"LIPID S-diacylglycerol cysteine","type":"exact"},{"name":"S-(1-2'-oleoyl-3'-palmitoyl-glycerol)cysteine","type":"exact"},{"name":"S-(2',3'-diacylglycerol)-L-cysteine","type":"exact"},{"name":"S-diacylglycerol-L-cysteine","type":"exact"},{"name":"SAcyl2GlyceroCys","type":"exact"},{"name":"diacylglycerol","type":"related"}],"termid":"MOD:00116"}


id: GO:0046678
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to antibiotic","termid":"GO:0046677"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to bacteriocin","synonyms":[{"name":"bacteriocin susceptibility/resistance","type":"related"}],"termid":"GO:0046678"}


id: PBO:0090958
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit S19","termid":"PBO:0090958"}


id: MONDO:0034989
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by intrauterine and postnatal growth restriction, global developmental delay, intellectual disability, and dysmorphic facial features (such as broad nasal root, anteverted nares, long philtrum, low-set and posteriorly rotated ears, and short neck). Additional reported manifestations are microcephaly, short stature, vertebral abnormalities, joint laxity, ocular, cardiac, and renal defects, and minor limb anomalies. Brain imaging may show hypoplastic corpus callosum, delayed myelination, and cerebral atrophy.","definition_xrefs":["Orphanet:508498"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability-cardiac anomalies-short stature-joint laxity syndrome","secondary_identifiers":["UMLS:C5568572","GARD:17948","MEDGEN:1799995"],"termid":"MONDO:0034989","xrefs":{"Monarch":{"xref_id":"0034989"}}}


id: GO:0002085
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.","definition_xrefs":["PMID:16678814","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of anatomical structure morphogenesis","termid":"GO:0022603"},{"relation_name":"is_a","term_name":"negative regulation of epithelial cell differentiation","termid":"GO:0030857"},{"relation_name":"is_a","term_name":"regulation of embryonic development","termid":"GO:0045995"},{"relation_name":"is_a","term_name":"regulation of timing of cell differentiation","termid":"GO:0048505"},{"relation_name":"negatively_regulates","term_name":"neuroepithelial cell differentiation","termid":"GO:0060563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"inhibition of neuroepithelial cell differentiation","synonyms":[{"name":"negative regulation of neural plate formation","type":"narrow"},{"name":"repression of premature neural plate formation","type":"narrow"}],"termid":"GO:0002085"}


id: PBO:0026968
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_swollen_pear-shaped_vegetative_cell","termid":"PBO:0026968"}


id: PBO:0059716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO2 pseudogene 24","termid":"PBO:0059716"}


id: FYPO:0006793
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A biological process phenotype in which the specificity between a meiotic driver gene and a drive suppressor gene differs from that observed when both genes are wild type. Meiotic drive results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to such that are unequally represented (i.e. the \\\"driver\\\" is overrepresented) among the surviving products of meiosis.","definition_xrefs":["PomBase:mah","PMID:30475921"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal biological process","termid":"FYPO:0005447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"altered meiotic drive suppression specificity","synonyms":[{"name":"abnormal meiotic drive suppression specificity","type":"exact"},{"name":"abnormal specificity of suppression of meiotic drive","type":"exact"}],"termid":"FYPO:0006793"}


id: PBO:0041135
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BTB domain containing 18","termid":"PBO:0041135"}


id: PR:Q9UU99
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC23B6.04c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UU99"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CRAL-TRIO domain-containing protein C23B6.04c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC23B6.04c","synonyms":[{"name":"Spom972h-SPCC23B6.04c","type":"exact"}],"termid":"PR:Q9UU99"}


id: _global:seeAlso
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"seeAlso","secondary_identifiers":["http://www.w3.org/2000/01/rdf-schema#seeAlso"],"termid":"_global:seeAlso","xrefs":{"Monarch":{"xref_id":"seeAlso"}}}


id: GO:0071447
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to hydroperoxide","termid":"GO:0033194"},{"relation_name":"is_a","term_name":"cellular response to oxidative stress","termid":"GO:0034599"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to hydroperoxide","termid":"GO:0071447"}


id: PBO:0039488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 20 family member A11, pseudogene","termid":"PBO:0039488"}


id: PBO:0052605
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kaptin, actin binding protein","termid":"PBO:0052605"}


id: GO:0005792
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete microsome (obsolete GO:0005792)","secondary_identifiers":["Wikipedia:Microsome"],"synonyms":[{"name":"microsomal membrane","type":"related"},{"name":"microsome","type":"exact"}],"termid":"GO:0005792"}


id: GO:0005304
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid.","definition_xrefs":["GOC:mtg_transport","GOC:ai","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic cation transmembrane transporter activity","termid":"GO:0015101"},{"relation_name":"is_a","term_name":"neutral L-amino acid transmembrane transporter activity","termid":"GO:0015175"},{"relation_name":"is_a","term_name":"L-amino acid transmembrane transporter activity","termid":"GO:0015179"},{"relation_name":"is_a","term_name":"branched-chain amino acid transmembrane transporter activity","termid":"GO:0015658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"L-valine transmembrane transporter activity","synonyms":[{"name":"L-valine transporter activity","type":"broad"},{"name":"isoleucine/valine:sodium symporter activity","type":"narrow"},{"name":"leucine/isoleucine/valine porter activity","type":"narrow"},{"name":"leucine/valine/isoleucine permease activity","type":"narrow"},{"name":"valine/tyrosine/tryptophan permease activity","type":"narrow"}],"termid":"GO:0005304"}


id: GO:0004740
data:
  {"annotated_genes":["SJAG_01402"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74919],"is_not":false,"summary":null,"term":"GO:0004740"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + L-seryl-[pyruvate dehydrogenase E1 alpha subunit] = ADP + H+ + O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit].","definition_xrefs":["RHEA:23052"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein serine/threonine kinase activity","termid":"GO:0004674"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01402":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0004672"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016301"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016740","GO:0004672","GO:0016301","GO:0140096"],"is_obsolete":false,"name":"pyruvate dehydrogenase (acetyl-transferring) kinase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-203946","EC:2.7.11.2","MetaCyc:2.7.11.2-RXN"],"synonyms":[{"name":"PDH kinase activity","type":"related"},{"name":"PDHK","type":"related"},{"name":"PDK","type":"related"},{"name":"pyruvate dehydrogenase kinase (phosphorylating) activity","type":"related"},{"name":"pyruvate dehydrogenase kinase activity","type":"related"}],"termid":"GO:0004740","terms_by_termid":{"GO:0004740":null}}


id: GO:0043319
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of T cell mediated cytotoxicity","termid":"GO:0001916"},{"relation_name":"is_a","term_name":"positive regulation of leukocyte degranulation","termid":"GO:0043302"},{"relation_name":"is_a","term_name":"regulation of cytotoxic T cell degranulation","termid":"GO:0043317"},{"relation_name":"positively_regulates","term_name":"cytotoxic T cell degranulation","termid":"GO:0043316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0016192"],"is_obsolete":false,"name":"positive regulation of cytotoxic T cell degranulation","synonyms":[{"name":"activation of cytotoxic T cell degranulation","type":"narrow"},{"name":"positive regulation of cytotoxic T cell granule exocytosis","type":"exact"},{"name":"positive regulation of cytotoxic T lymphocyte degranulation","type":"exact"},{"name":"positive regulation of cytotoxic T lymphocyte granule exocytosis","type":"exact"},{"name":"positive regulation of cytotoxic T-cell degranulation","type":"exact"},{"name":"positive regulation of cytotoxic T-cell granule exocytosis","type":"exact"},{"name":"positive regulation of cytotoxic T-lymphocyte degranulation","type":"exact"},{"name":"positive regulation of cytotoxic T-lymphocyte granule exocytosis","type":"exact"},{"name":"stimulation of cytotoxic T cell degranulation","type":"narrow"},{"name":"up regulation of cytotoxic T cell degranulation","type":"exact"},{"name":"up-regulation of cytotoxic T cell degranulation","type":"exact"},{"name":"upregulation of cytotoxic T cell degranulation","type":"exact"}],"termid":"GO:0043319"}


id: PBO:0041387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 5 open reading frame 46","termid":"PBO:0041387"}


id: PBO:0083144
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps ORF AIM10/YER087W","termid":"PBO:0083144"}


id: MONDO:0001443
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The formation of dense connective tissue in the tympanic membrane that does not necessarily cause or lead to loss of hearing.","definition_xrefs":["MESH:D063371"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tympanic membrane disorder","termid":"MONDO:0003648"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tympanosclerosis","secondary_identifiers":["ICD9:385.00","UMLS:C0395887","ICD10CM:H74.0","MEDGEN:473094","ICD9:385.09","SCTID:23606001","DOID:1214","icd11.foundation:28175464"],"termid":"MONDO:0001443","xrefs":{"Monarch":{"xref_id":"0001443"}}}


id: GO:0005747
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.","definition_xrefs":["GOC:mtg_sensu","ISBN:0198547684"],"gene_count":0,"genotype_count":0,"name":"obsolete mitochondrial respiratory chain complex I (obsolete GO:0005747)","termid":"GO:0005747"}


id: PBO:0113217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Modulator of cellular lipid distribution; localizes to ER-PM and ER-mitochondria contact sites; shares homology with lipid transfer proteins Vps13p and Atg2p; homolog of D. melanogaster Hobbit protein","termid":"PBO:0113217"}


id: PATO:0000971
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000971 absolute permeability (obsolete PATO:0000971)","termid":"PATO:0000971"}


id: PBO:0038752
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin related protein 2","termid":"PBO:0038752"}


id: PR:O42862
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- atg14 gene.","definition_xrefs":["UniProtKB:O42862","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy-related protein 14 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC25A8.02","synonyms":[{"name":"Spom972h-atg14","type":"exact"}],"termid":"PR:O42862"}


id: GO:0030350
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins.","definition_xrefs":["PMID:3198610","PMID:8710843"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA binding","termid":"GO:0003729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003723"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0003723"],"is_obsolete":false,"name":"iron-responsive element binding","synonyms":[{"name":"IRE binding","type":"exact"}],"termid":"GO:0030350"}


id: GO:1902195
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving isovaleryl-CoA(4-).","definition_xrefs":["PMID:11231285","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fatty-acyl-CoA metabolic process","termid":"GO:0035337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0055086","GO:0044281","GO:0006790","GO:0006629"],"is_obsolete":false,"name":"isovaleryl-CoA(4-) metabolic process","synonyms":[{"name":"isovaleryl-CoA(4-) metabolism","type":"exact"}],"termid":"GO:1902195"}


id: PBO:0110315
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase feature property types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"insdc_protein_id","termid":"PBO:0110315"}


id: GO:0050137
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O2 + H+ + NADPH = 2 H2O + NADP+.","definition_xrefs":["EC:1.11.1.2","RHEA:15173"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peroxidase activity","termid":"GO:0004601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"NADPH peroxidase activity","secondary_identifiers":["MetaCyc:NADPH-PEROXIDASE-RXN","KEGG_REACTION:R00113"],"synonyms":[{"name":"NADP peroxidase activity","type":"related"},{"name":"NADPH:hydrogen-peroxide oxidoreductase activity","type":"related"},{"name":"TPN peroxidase activity","type":"related"},{"name":"TPNH peroxidase activity","type":"related"},{"name":"nicotinamide adenine dinucleotide phosphate peroxidase activity","type":"related"},{"name":"triphosphopyridine nucleotide peroxidase activity","type":"related"}],"termid":"GO:0050137"}


id: PBO:0060310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myosin light chain kinase","termid":"PBO:0060310"}


id: PBO:0091553
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiosis specific Smp foci lncRNA Omt3","termid":"PBO:0091553"}


id: MONDO:0019620
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital esophageal diverticulum is a rare, non-syndromic malformation of the esophagus, present at birth, and characterized by a false diverticulum, most often located in the upper, posterior esophagus. Many patients are asymptomatic, but respiratory distress, food regurgitation, dysphagia, chest pain, aspiration pneumonia and discomfort are typical presenting manifestations.","definition_xrefs":["Orphanet:91358"],"direct_ancestors":[{"relation_name":"is_a","term_name":"esophageal disorder","termid":"MONDO:0003749"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"congenital esophageal diverticulum","secondary_identifiers":["icd11.foundation:42183618","MEDGEN:539704","SCTID:204667006","GARD:19165","ICD9:750.4","UMLS:C0266133"],"synonyms":[{"name":"congenital esophageal pouch","type":"exact"}],"termid":"MONDO:0019620","xrefs":{"Monarch":{"xref_id":"0019620"}}}


id: PBO:0061156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NmrA like redox sensor 1","termid":"PBO:0061156"}


id: PBO:0080921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"YWHAQ pseudogene","termid":"PBO:0080921"}


id: GO:0090449
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink.","definition_xrefs":["PMID:22864417"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phloem loading","termid":"GO:0110126"},{"relation_name":"is_a","term_name":"glucosinolate transport","termid":"GO:1901349"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"phloem glucosinolate loading","termid":"GO:0090449"}


id: PBO:0024840
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"not functionally complemented by S. cerevisiae DSS1","termid":"PBO:0024840"}


id: GO:0031609
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.","definition_xrefs":["GOC:mah","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteasome core complex, beta-subunit complex","termid":"GO:0019774"},{"relation_name":"part_of","term_name":"cytosolic proteasome core complex","termid":"GO:0031603"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005829"},{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005829","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"cytosolic proteasome core complex, beta-subunit complex","termid":"GO:0031609"}


id: FYPO:0007676
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the directed movement of sterols within cells is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah","PMID:32320462"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal transport","termid":"FYPO:0001071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0001312","FYPO:0000257"],"is_obsolete":false,"name":"normal intracellular sterol transport","termid":"FYPO:0007676"}


id: MOD:00435
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"Covalent modification of a peptide or protein amino acid phosphorylated serine with a secondary loss of a neutral trihydrogen phosphate molecular fragment.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"O-phospho-L-serine","termid":"MOD:00046"},{"relation_name":"is_a","term_name":"phosphorylated residue with neutral loss of phosphate","termid":"MOD:01151"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O-phospho-L-serine with neutral loss of phosphate","synonyms":[{"name":"dPhosOPhosSer","type":"exact"}],"termid":"MOD:00435"}


id: PBO:0049878
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hephaestin like 1","termid":"PBO:0049878"}


id: GO:0040022
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.","definition_xrefs":["GOC:ems"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hermaphrodite germ-line sex determination","termid":"GO:0040021"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"feminization of hermaphroditic germ-line","termid":"GO:0040022"}


id: MONDO:0003431
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An adenoma in which the neoplastic epithelial cells are admixed with adipose tissue cells.","definition_xrefs":["NCIT:C4159"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenoma","termid":"MONDO:0004972"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipoadenoma","secondary_identifiers":["UMLS:C0334325","DOID:5398","ICDO:8324/0","MEDGEN:83133"],"synonyms":[{"name":"adenolipoma, benign","type":"exact"},{"name":"lipoadenoma","type":"exact"},{"name":"lipoadenoma (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0003431","xrefs":{"Monarch":{"xref_id":"0003431"}}}


id: PBO:0018176
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sirtuin family histone deacetylase Hst2","termid":"PBO:0018176"}


id: PBO:0055294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2721","termid":"PBO:0055294"}


id: PBO:0085150
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nucleoside monophosphate and nucleoside diphosphate kinase; functions in the de novo biosynthesis of pyrimidine deoxyribonucleotides; thymidylate/uridylate kinase that converts nucleoside monophosphates, dTMP and dUMP to nucleoside diphosphates, dTDP and dUDP; nucleoside diphosphate kinase that converts nucleoside diphosphates, dTDP and dUDP to dTTP and dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe tmp1; human homolog DTYMK can complement the cdc8 null mutant","termid":"PBO:0085150"}


id: PBO:0000080
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S. pombe specific 5Tm protein family","termid":"PBO:0000080"}


id: PBO:0054816
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2229","termid":"PBO:0054816"}


id: PBO:0039201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aldo-keto reductase family 1 member B1 pseudogene 4","termid":"PBO:0039201"}


id: PBO:0089204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial heat shock protein Hsp10","termid":"PBO:0089204"}


id: MONDO:0004231
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A squamous cell carcinoma that arises from the breast parenchyma and is characterized by the presence of spindle-shaped malignant cells.","definition_xrefs":["NCIT:C40358"],"direct_ancestors":[{"relation_name":"is_a","term_name":"squamous cell breast carcinoma","termid":"MONDO:0006056"},{"relation_name":"is_a","term_name":"sarcomatoid squamous cell carcinoma","termid":"MONDO:0021663"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"spindle cell variant squamous cell breast carcinoma","secondary_identifiers":["ONCOTREE:MASCC","UMLS:C1519487","MEDGEN:274270","DOID:7460"],"synonyms":[{"name":"metaplastic adenocarcinoma with spindle cell differentiation","type":"related"},{"name":"squamous cell breast carcinoma, spindle cell variant","type":"exact"}],"termid":"MONDO:0004231","xrefs":{"Monarch":{"xref_id":"0004231"}}}


id: PBO:0050326
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 pseudogene 28","termid":"PBO:0050326"}


id: MOD:01154
data:
  {"annotated_genes":["SJAG_02902","SJAG_03632","SJAG_02980","SJAG_03524"],"annotation_feature_type":"gene","cv_annotations":{"PSI-MOD":[{"annotations":[80263,80309,80432,80489],"is_not":false,"summary":null,"term":"MOD:01154"}]},"cv_name":"PSI-MOD","definition":"A protein modification that effectively converts a source amino acid to pyruvic acid.","definition_xrefs":["PubMed:8464063","PubMed:10085076","PubMed:3042771","RESID:AA0127"],"direct_ancestors":[{"relation_name":"is_a","term_name":"residues isobaric at 71.0-71.1 Da","termid":"MOD:00769"},{"relation_name":"is_a","term_name":"modified residue that can arise from different natural residues","termid":"MOD:00859"}],"gene_count":4,"genes_by_uniquename":{"SJAG_02902":null,"SJAG_02980":null,"SJAG_03524":null,"SJAG_03632":null},"genotype_count":0,"is_obsolete":false,"name":"pyruvic acid","references_by_uniquename":{"PMID:36408920":null},"synonyms":[{"name":"2-oxopropanoic acid","type":"exact"},{"name":"MOD_RES Pyruvic acid (Cys)","type":"exact"},{"name":"MOD_RES Pyruvic acid (Ser)","type":"exact"},{"name":"pyruvic acid","type":"exact"}],"termid":"MOD:01154","terms_by_termid":{"MOD:01154":null}}


id: MONDO:0007817
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Immediate hypersensitivity reaction - type I reaction, involves immunoglobulin E (IgE)-mediated release of chemical mediators from mast cells and basophils. Th2 cells produce IL-4 and IL-13, which then act on B cells to promote the production of antigen-specific IgE. Reexposure to the antigen can then result in the antigen binding to and cross-linking the bound IgE antibodies on the mast cells and basophils. This causes the release of preformed mediators (histamine, tryptase, tryptase, chemotactic factors), newly synthesized mediators (leukotrienes, prostaglandin, thromboxane, platelet-activating factor, adenosine, bradykinin), and cytokines from these cells that results in structural and functional changes to the affected tissue.","definition_xrefs":["NCIT:C3116"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"atopic eczema","termid":"MONDO:0004980"},{"relation_name":"is_a","term_name":"hypersensitivity reaction disease","termid":"MONDO:0000605"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"IgE responsiveness, atopic","secondary_identifiers":["OMIM:147050","MESH:C564133","UMLS:C1840253","MEDGEN:327063"],"synonyms":[{"name":"Atopic hypersensitivity","type":"related"},{"name":"IGER","type":"related"},{"name":"IgE response underlying allergic asthma and rhinitis","type":"related"},{"name":"IgE responsiveness, ATOPIC","type":"related"},{"name":"IgE responsiveness, atopic","type":"exact"},{"name":"IgE, elevated level of","type":"exact"},{"name":"IgE, level of","type":"related"},{"name":"Immunoglobulin E, basic level of, in serum","type":"related"},{"name":"atopy, susceptibility to","type":"related"},{"name":"immediate hypersensitivity","type":"exact"},{"name":"type 1 hypersensitivity","type":"exact"},{"name":"type 1 hypersensitivity reaction","type":"exact"},{"name":"type I hypersensitivity","type":"exact"},{"name":"type I hypersensitivity reaction","type":"exact"},{"name":"type I immediate hypersensitivity reaction","type":"exact"}],"termid":"MONDO:0007817","xrefs":{"Monarch":{"xref_id":"0007817"}}}


id: PBO:0063749
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PHB1 pseudogene 14","termid":"PBO:0063749"}


id: PBO:0071533
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPL34 pseudogene 36","termid":"PBO:0071533"}


id: PBO:0056866
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule associated monooxygenase, calponin and LIM domain containing 2","termid":"PBO:0056866"}


id: PBO:0074589
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 5A","termid":"PBO:0074589"}


id: PBO:0111797
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pumilio family","termid":"PBO:0111797"}


id: PBO:0046492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ETS transcription factor ERG","termid":"PBO:0046492"}


id: PBO:0067240
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 311, pseudogene","termid":"PBO:0067240"}


id: GO:0032816
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of natural killer cell activation.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of natural killer cell activation","termid":"GO:0032814"},{"relation_name":"is_a","term_name":"positive regulation of lymphocyte activation","termid":"GO:0051251"},{"relation_name":"positively_regulates","term_name":"natural killer cell activation","termid":"GO:0030101"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of natural killer cell activation","synonyms":[{"name":"activation of natural killer cell activation","type":"narrow"},{"name":"positive regulation of NK cell activation","type":"exact"},{"name":"stimulation of natural killer cell activation","type":"narrow"},{"name":"up regulation of natural killer cell activation","type":"exact"},{"name":"up-regulation of natural killer cell activation","type":"exact"},{"name":"upregulation of natural killer cell activation","type":"exact"}],"termid":"GO:0032816"}


id: GO:0004519
data:
  {"annotated_genes":["SJAG_01648","SJAG_00754","SJAG_04916","SJAG_02156","SJAG_01433","SJAG_02828","SJAG_04006","SJAG_MIT07","SJAG_00772","SJAG_01623","SJAG_03952","SJAG_04019","SJAG_02553","SJAG_02298","SJAG_00306","SJAG_01463","SJAG_04527","SJAG_01581","SJAG_03425","SJAG_MIT05","SJAG_04587","SJAG_04519","SJAG_02556","SJAG_02547","SJAG_03328","SJAG_01551","SJAG_03962","SJAG_05373","SJAG_01173","SJAG_03234","SJAG_MIT06","SJAG_00955","SJAG_04183","SJAG_03675","SJAG_01884","SJAG_01979","SJAG_01260","SJAG_02790","SJAG_04752","SJAG_04582","SJAG_00997","SJAG_03994","SJAG_01044","SJAG_01262","SJAG_02374","SJAG_00400","SJAG_02039","SJAG_01569","SJAG_00623","SJAG_02621","SJAG_06613","SJAG_06022","SJAG_02708","SJAG_03796","SJAG_03539","SJAG_01948","SJAG_04885","SJAG_01471","SJAG_04198","SJAG_01936","SJAG_04091","SJAG_02031","SJAG_04435","SJAG_04907","SJAG_05237","SJAG_03689","SJAG_01476","SJAG_01832"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[60777,64371,67171,73526,87920,100096,118833,118841,118842],"is_not":false,"summary":null,"term":"GO:0004519"},{"annotations":[118563],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990599"},{"annotations":[74142],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048257"},{"annotations":[80118,69711],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042781"},{"annotations":[105746],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990043"},{"annotations":[103953],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990601"},{"annotations":[74342,66078,72443,75518,71107,78220],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017108"},{"annotations":[78974,94530,100975,59609,78348,74137],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008821"},{"annotations":[100977],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106332"},{"annotations":[117894],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070551"},{"annotations":[91497],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990174"},{"annotations":[73499,59572,76503,67624,60454],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004525"},{"annotations":[115189,104357,105465,96292,115102,96587,104575,105466,94505,70985,113282,118389],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000171"},{"annotations":[70988,101856,68236,94506,104358,115103,96588,60487,63501],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004526"},{"annotations":[63550,71583,112715,116123,108800,72261,107263,69738,76486,77688,79199],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004521"},{"annotations":[76076],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016891"},{"annotations":[76827],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008419"},{"annotations":[102743,88092,75763,80031],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004523"},{"annotations":[109832,71580,79085,110619],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000014"},{"annotations":[117477,71139,72815,78790],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000213"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.","definition_xrefs":["ISBN:0198547684","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclease 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id: GO:1900406
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion.","definition_xrefs":["GOC:mah","GOC:TermGenie","PMID:1112904"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter (obsolete GO:1900406)","termid":"GO:1900406"}


id: PBO:0012555
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"origin recognition complex subunit Orp3","termid":"PBO:0012555"}


id: PBO:0110259
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase II complex subunit Rpb2","termid":"PBO:0110259"}


id: GO:0004745
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: all-trans-retinol--[retinol-binding protein] + NAD+ = all-trans-retinal--[retinol-binding protein] + H+ + NADH. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein (CRBP1), but has higher affinity for the bound form.","definition_xrefs":["RHEA:48488"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alcohol dehydrogenase (NAD+) activity","termid":"GO:0004022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"all-trans-retinol dehydrogenase (NAD+) activity","secondary_identifiers":["Reactome:R-HSA-5362518","EC:1.1.1.105","Reactome:R-HSA-2454081","Reactome:R-HSA-5362721","Reactome:R-HSA-2466832","MetaCyc:RETINOL-DEHYDROGENASE-RXN","Reactome:R-HSA-5362564"],"synonyms":[{"name":"all-trans retinol dehydrogenase activity","type":"broad"},{"name":"retinal reductase activity","type":"broad"},{"name":"retinene reductase activity","type":"broad"},{"name":"retinol (vitamin A1) dehydrogenase activity","type":"broad"},{"name":"retinol dehydrogenase activity","type":"broad"}],"termid":"GO:0004745"}


id: FYPO:0001430
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which progression through the mitotic cell cycle is arrested before cells have replicated genomic DNA, under conditions where arrest does not normally occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_output","term_name":"increased number of cells with 1C DNA content","termid":"FYPO:0001974"},{"relation_name":"is_a","term_name":"abnormally arrested mitotic cell cycle progression","termid":"FYPO:0000502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0000631"],"is_obsolete":false,"name":"abnormal mitotic cell cycle arrest with unreplicated DNA","synonyms":[{"name":"abnormal cell cycle arrest with unreplicated DNA during mitotic cell cycle","type":"related"},{"name":"abnormal mitotic cell cycle arrest with 1C DNA content","type":"exact"},{"name":"abnormal mitotic cell cycle arrest with unreplicated DNA during vegetative growth","type":"exact"}],"termid":"FYPO:0001430"}


id: GO:0070671
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to cytokine","termid":"GO:0034097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to interleukin-12","synonyms":[{"name":"response to IL-12","type":"exact"}],"termid":"GO:0070671"}


id: GO:0036221
data:
  {"annotated_genes":["SJAG_01651"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[96902],"is_not":false,"summary":null,"term":"GO:0036221"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: UTP + H2O = UMP + H+ + diphosphate.","definition_xrefs":["PMID:17899088","RHEA:29395","GOC:dgf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside triphosphate diphosphatase activity","termid":"GO:0047429"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01651":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0047429"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674","GO:0047429"],"is_obsolete":false,"name":"UTP diphosphatase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["KEGG_REACTION:R00662"],"synonyms":[{"name":"uridine triphosphate pyrophosphohydrolase activity","type":"exact"}],"termid":"GO:0036221","terms_by_termid":{"GO:0036221":null}}


id: PBO:0040799
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"basic helix-loop-helix family member e22","termid":"PBO:0040799"}


id: PBO:0053742
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 968","termid":"PBO:0053742"}


id: MONDO:0002434
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cancer involving a oculomotor nerve.","definition_xrefs":["MONDO:patterns/cancer"],"direct_ancestors":[{"relation_name":"is_a","term_name":"malignant cranial nerve neoplasm","termid":"MONDO:0002433"},{"relation_name":"is_a","term_name":"oculomotor nerve neoplasm","termid":"MONDO:0002435"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"oculomotor nerve cancer","secondary_identifiers":["UMLS:C0686417","DOID:2816","MEDGEN:195786","NCIT:C6995","SCTID:93929003"],"synonyms":[{"name":"IIIrd cranial nerve neoplasm, malignant","type":"exact"},{"name":"cancer of oculomotor nerve","type":"exact"},{"name":"malignant neoplasm of oculomotor nerve","type":"exact"},{"name":"malignant oculomotor nerve neoplasm","type":"exact"},{"name":"malignant oculomotor nerve tumor","type":"related"},{"name":"malignant oculomotor nerve tumour","type":"related"},{"name":"oculomotor nerve cancer","type":"exact"},{"name":"oculomotor nerve neoplasm, malignant","type":"exact"},{"name":"primary malignant neoplasm of oculomotor nerve","type":"exact"}],"termid":"MONDO:0002434","xrefs":{"Monarch":{"xref_id":"0002434"}}}


id: PBO:0036185
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_threonine_phosphorylation_during_mitosis","termid":"PBO:0036185"}


id: GO:0102725
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 24-methyldesmosterol reductase activity (obsolete GO:0102725)","termid":"GO:0102725"}


id: PBO:0052050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KANSL1 antisense RNA 1","termid":"PBO:0052050"}


id: PBO:0070918
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L17 pseudogene 26","termid":"PBO:0070918"}


id: PBO:0083303
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of MRS2 gene required for respiratory growth","termid":"PBO:0083303"}


id: GO:0035310
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.","definition_xrefs":["PMID:10860999"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell fate specification involved in pattern specification","termid":"GO:0060573"},{"relation_name":"part_of","term_name":"wing and notum subfield formation","termid":"GO:0035309"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"notum cell fate specification","termid":"GO:0035310"}


id: PBO:0074720
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 79B","termid":"PBO:0074720"}


id: GO:0097279
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.","definition_xrefs":["GOC:rv","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histamine secretion mediated by immunoglobulin","termid":"GO:0097280"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0023052","GO:0051179"],"is_obsolete":false,"name":"histamine secretion mediated by IgE immunoglobulin","synonyms":[{"name":"Ig-mediated histamine release","type":"broad"},{"name":"histamine secretion mediated by IgE antibody","type":"exact"}],"termid":"GO:0097279"}


id: PR:P36579
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- arf1 gene.","definition_xrefs":["UniProtKB:P36579","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP-ribosylation factor 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC4F6.18c","synonyms":[{"name":"Spom972h-arf1","type":"exact"}],"termid":"PR:P36579"}


id: PBO:0081990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger and SCAN domain containing 20","termid":"PBO:0081990"}


id: PBO:0060912
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NEXN antisense RNA 1","termid":"PBO:0060912"}


id: GO:0102764
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 6-deoxotyphasterol C-23 hydroxylase activity (obsolete GO:0102764)","termid":"GO:0102764"}


id: PBO:0030784
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-vacuoles_present_in_increased_numbers_during_vegetative_growth","termid":"PBO:0030784"}


id: PBO:0071116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 118","termid":"PBO:0071116"}


id: PBO:0086801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; YCL001W-A gene has similarity to DOM34 and is present in a region duplicated between chromosomes XIV and III","termid":"PBO:0086801"}


id: PBO:0089657
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EPS15 repeat family actin cortical patch component Ede1","termid":"PBO:0089657"}


id: MONDO:0008759
data:
  {"annotated_genes":["SJAG_02464"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86806],"is_not":false,"summary":null,"term":"MONDO:0008759"}]},"cv_name":"mondo","definition":"A rare, genetic, inborn error of metabolism disorder characterized by neonatal-onset of developmental delay, hypotonia, hepatomegaly, lactic acidemia, increased creatine kinase levels, elevated alpha-ketoglutaric acid in urine, and a decreased plasma beta-hydroxybutyrate-to-acetoacetate ratio. Pyruvate dehydrogenase deficiency can be associated, leading to hypoglycemia and neurologic anomalies, including seizures.","definition_xrefs":["Orphanet:31"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn mitochondrial metabolism disorder","termid":"MONDO:0004069"},{"relation_name":"is_a","term_name":"tricarboxylic acid cycle disorder","termid":"MONDO:0016790"},{"relation_name":"is_a","term_name":"hereditary peripheral neuropathy","termid":"MONDO:0020127"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02464":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066","MONDO:0005244"],"is_obsolete":false,"name":"oxoglutaricaciduria","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C2752074","DOID:0081326","SCTID:733630004","MESH:C536582","GARD:617","MEDGEN:414553","OMIM:203740"],"synonyms":[{"name":"2 alpha ketoglutarate dehydrogenase deficiency","type":"related"},{"name":"2-ketoglutarate dehydrogenase deficiency","type":"related"},{"name":"ALPHA-ketoglutarate dehydrogenase deficiency","type":"related"},{"name":"Alpha KGD deficiency","type":"related"},{"name":"Alpha-Kgd deficiency","type":"related"},{"name":"Alpha-ketoglutarate dehydrogenase deficiency","type":"exact"},{"name":"Oxoglutaric aciduria","type":"related"},{"name":"oxoglutarate dehydrogenase deficiency","type":"exact"}],"termid":"MONDO:0008759","terms_by_termid":{"MONDO:0008759":null},"xrefs":{"Monarch":{"xref_id":"0008759"}}}


id: MONDO:0040654
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant form of oculocutaneous albinism.","definition_xrefs":["MONDO:patterns/autosomal_dominant"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"oculocutaneous albinism","termid":"MONDO:0018910"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant oculocutaneous albinism","secondary_identifiers":["MEDGEN:541335","UMLS:C0268499","SCTID:79417003"],"synonyms":[{"name":"autosomal dominant oculocutaneous albinism","type":"exact"},{"name":"oculocutaneous albinism, autosomal dominant","type":"exact"}],"termid":"MONDO:0040654","xrefs":{"Monarch":{"xref_id":"0040654"}}}


id: GO:0035372
data:
  {"annotated_genes":["SJAG_02695","SJAG_02045"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70384],"is_not":false,"summary":null,"term":"GO:0035372"},{"annotations":[96775],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904518"}]},"cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained at, a microtubule.","definition_xrefs":["GOC:bf","GOC:lb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to microtubule cytoskeleton","termid":"GO:0072698"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02045":null,"SJAG_02695":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to microtubule","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"protein localisation to microtubule","type":"exact"}],"termid":"GO:0035372","terms_by_termid":{"GO:0035372":null,"GO:1904518":null}}


id: PBO:0046394
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"erythrocyte membrane protein band 4.1 like 1","termid":"PBO:0046394"}


id: PBO:0060098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND5 pseudogene 45","termid":"PBO:0060098"}


id: PBO:0056336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitogen-activated protein kinase kinase kinase 19","termid":"PBO:0056336"}


id: MONDO:0002929
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"lung disorder","termid":"MONDO:0005275"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pulmonary immaturity","secondary_identifiers":["DOID:424","ICD9:770.4","MEDGEN:542574","SCTID:42908004","UMLS:C0270163"],"synonyms":[{"name":"primary atelectasis of newborn","type":"exact"},{"name":"primary atelectasis, in perinatal period","type":"exact"}],"termid":"MONDO:0002929","xrefs":{"Monarch":{"xref_id":"0002929"}}}


id: PBO:0031183
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_mating_efficiency","termid":"PBO:0031183"}


id: PBO:0073811
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC6A14 pseudogene 2","termid":"PBO:0073811"}


id: PBO:0089237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malate dehydrogenase Mdh1","termid":"PBO:0089237"}


id: PR:Q7LKZ5
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein FAM50A that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04439","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FAM50 family protein C1020.12c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1020.12c","secondary_identifiers":["UniProtKB:Q7LKZ5"],"synonyms":[{"name":"Spom972h-FAM50A","type":"exact"}],"termid":"PR:Q7LKZ5"}


id: FYPO:0004964
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer actin cortical patches than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin cortical patch","termid":"FYPO:0003987"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0004803"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0004803","FYPO:0000002","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"actin cortical patches present in decreased numbers","synonyms":[{"name":"F-actin patches present in decreased numbers","type":"exact"},{"name":"actin cortical patches present in decreased numbers during mitotic cell cycle","type":"related"},{"name":"actin cortical patches present in decreased numbers during vegetative growth","type":"exact"},{"name":"actin cortical patches present in reduced numbers","type":"exact"},{"name":"actin patches present in decreased numbers","type":"exact"},{"name":"decreased actin cortical patch formation during vegetative growth","type":"related"},{"name":"decreased number of actin cortical patches during vegetative growth","type":"exact"},{"name":"fewer actin cortical patches present during vegetative growth","type":"exact"}],"termid":"FYPO:0004964"}


id: MONDO:0014907
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Jeune syndrome","termid":"MONDO:0018770"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"short-rib thoracic dysplasia 15 with polydactyly","secondary_identifiers":["GARD:16185","OMIM:617088","MEDGEN:934691","UMLS:C4310724"],"synonyms":[{"name":"SRTD15","type":"exact"},{"name":"short-rib thoracic dysplasia 15 with polydactyly","type":"exact"},{"name":"short-rib thoracic dysplasia 15 with polydactyly; SRTD15","type":"exact"}],"termid":"MONDO:0014907","xrefs":{"Monarch":{"xref_id":"0014907"}}}


id: GO:0140892
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction chloride(in) + 2 hydrogencarbonate(out) + Na+(out) = chloride(out) + 2 hydrogencarbonate(in) + Na+(in).","definition_xrefs":["PMID:20389022","PMID:18577713","PMID:8189393"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium ion transmembrane transporter activity","termid":"GO:0015081"},{"relation_name":"is_a","term_name":"metal cation:monoatomic cation antiporter activity","termid":"GO:0140828"},{"relation_name":"is_a","term_name":"chloride:bicarbonate antiporter activity","termid":"GO:0140900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"sodium,bicarbonate:chloride antiporter activity","secondary_identifiers":["TC:2.A.31.2.4"],"synonyms":[{"name":"sodium,hydrogencarbonate:chloride antiporter activity","type":"exact"},{"name":"sodium-dependent chloride/bicarbonate exchanger activity","type":"exact"}],"termid":"GO:0140892"}


id: GO:0005459
data:
  {"annotated_genes":["SJAG_04162","SJAG_01177","SJAG_04697"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74683,75714,88157],"is_not":false,"summary":null,"term":"GO:0005459"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.","definition_xrefs":["GOC:ai","ISBN:0815340729","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine nucleotide-sugar transmembrane transporter activity","termid":"GO:0015165"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01177":null,"SJAG_04162":null,"SJAG_04697":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"UDP-galactose transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-5652099","Reactome:R-HSA-735702"],"termid":"GO:0005459","terms_by_termid":{"GO:0005459":null}}


id: PBO:0028949
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_localization_to_cell_tip","termid":"PBO:0028949"}


id: MONDO:0003395
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare sex cord-stromal tumor that arises from the testis. It is characterized by the presence of granulosa-like cells and Call-Exner bodies. There are two variants described, the adult and the juvenile.","definition_xrefs":["NCIT:C6357"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"benign female reproductive system neoplasm","termid":"MONDO:0000624"},{"relation_name":"is_a","term_name":"testicular sex cord-stromal neoplasm","termid":"MONDO:0003125"},{"relation_name":"is_a","term_name":"granulosa cell tumor","termid":"MONDO:0006036"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testicular granulosa cell tumor","secondary_identifiers":["UMLS:C1336709","MEDGEN:237001","DOID:5331"],"synonyms":[{"name":"granulosa cell neoplasm of testis","type":"related"},{"name":"granulosa cell neoplasm of the testis","type":"related"},{"name":"granulosa cell tumor of testis","type":"exact"},{"name":"granulosa cell tumor of the testis","type":"related"},{"name":"granulosa cell tumour of testis","type":"exact"},{"name":"granulosa cell tumour of the testis","type":"related"},{"name":"testicular granulosa cell neoplasm","type":"related"},{"name":"testicular granulosa cell tumor","type":"exact"},{"name":"testis granulosa cell tumor","type":"exact"},{"name":"testis granulosa cell tumour","type":"exact"}],"termid":"MONDO:0003395","xrefs":{"Monarch":{"xref_id":"0003395"}}}


id: MONDO:1011236
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Microphthalmia that occurs in water buffalo.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microphthalmia, non-human animal","termid":"MONDO:1010324"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microphthalmia, water buffalo","secondary_identifiers":["OMIA:000649-89462"],"termid":"MONDO:1011236","xrefs":{"Monarch":{"xref_id":"1011236"}}}


id: PBO:0028918
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_transcription_during_glucose_starvation","termid":"PBO:0028918"}


id: PBO:0077153
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TLC domain containing 3B","termid":"PBO:0077153"}


id: GO:0102817
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA = gentiodelphin + coenzyme A.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity (obsolete GO:0102817)","termid":"GO:0102817"}


id: MONDO:0022889
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"craniostenosis with congenital heart disease intellectual disability","termid":"MONDO:0022889","xrefs":{"Monarch":{"xref_id":"0022889"}}}


id: PBO:0069446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 711, pseudogene","termid":"PBO:0069446"}


id: PBO:0052281
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysine demethylase 7A","termid":"PBO:0052281"}


id: GO:0007386
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.","definition_xrefs":["ISBN:0879694238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anterior/posterior pattern specification","termid":"GO:0009952"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"compartment pattern specification","synonyms":[{"name":"compartment specification","type":"related"}],"termid":"GO:0007386"}


id: PBO:0027581
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_elongated_vegetative_cell_with_fragmented_DNA","termid":"PBO:0027581"}


id: PBO:0039554
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ANKRD49 pseudogene 1","termid":"PBO:0039554"}


id: MONDO:0024265
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Duane syndrome type 1 is the most common type of Duane syndrome, an eye movement disorder that is present at birth. People with Duane syndrome have restricted ability to move the affected eye(s) outward toward the ear (abduction) and/or inward toward the nose (adduction). The different types are distinguished by the eye movements that are most restricted. Duane syndrome type 1 is characterized by absent to very restricted abduction and normal to mildly restricted adduction. The eye opening (palpebral fissure) narrows and the eyeball retracts into the orbit with adduction. With abduction, the reverse occurs. One or both eyes may be affected. The majority of cases are sporadic (not inherited), while about 10% are familial. 70% of affected people do not have any other abnormalities at birth (isolated Duane syndrome). Treatment is mainly supportive and may include glasses or contact lenses for vision correction, eye patches, or surgery.","definition_xrefs":["GARD:0010763"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Duane retraction syndrome","termid":"MONDO:0007473"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Duane syndrome type 1","secondary_identifiers":["MEDGEN:201329","GARD:10763","OMIM:126800","SCTID:128082002","UMLS:C0994516"],"synonyms":[{"name":"DURS1","type":"exact"},{"name":"Drs","type":"related"},{"name":"Duane anomaly","type":"related"},{"name":"Duane retraction syndrome 1","type":"exact"},{"name":"Duane syndrome","type":"related"},{"name":"retraction syndrome","type":"related"}],"termid":"MONDO:0024265","xrefs":{"Monarch":{"xref_id":"0024265"}}}


id: PBO:0089192
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane glutathione transmembrane transporter Pgt1","termid":"PBO:0089192"}


id: FYPO:0002661
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is lower than normal when the cell is subject to heat shock.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased cellular trehalose 6-phosphate level","termid":"FYPO:0002660"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased cellular trehalose 6-phosphate level during heat shock","synonyms":[{"name":"decreased cellular trehalose 6-phosphate level during heat shock during mitotic cell cycle","type":"related"},{"name":"decreased cellular trehalose 6-phosphate level during vegetative growth and during heat shock","type":"exact"},{"name":"decreased cellular trehalose-6P level during heat shock","type":"exact"},{"name":"decreased trehalose 6-phosphate accumulation during heat shock","type":"related"},{"name":"reduced cellular trehalose 6-phosphate level during heat shock","type":"exact"}],"termid":"FYPO:0002661"}


id: GO:0046658
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.","definition_xrefs":["GOC:dos","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete anchored component of plasma membrane (obsolete GO:0046658)","synonyms":[{"name":"anchored to plasma membrane","type":"narrow"},{"name":"plasma membrane, GPI-anchored","type":"narrow"}],"termid":"GO:0046658"}


id: PBO:0077586
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thymopoietin","termid":"PBO:0077586"}


id: PBO:0090295
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RhoGEF for Rho1, Rgf3","termid":"PBO:0090295"}


id: GO:0047021
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NADP+ + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H+ + NADPH.","definition_xrefs":["EC:1.1.1.197","RHEA:11636"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"15-hydroxyprostaglandin dehydrogenase (NADP+) activity","secondary_identifiers":["MetaCyc:1.1.1.197-RXN","KEGG_REACTION:R04552"],"synonyms":[{"name":"(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity","type":"related"},{"name":"NADP-dependent 15-hydroxyprostaglandin dehydrogenase","type":"broad"},{"name":"NADP-linked 15-hydroxyprostaglandin dehydrogenase","type":"broad"},{"name":"NADP-specific 15-hydroxyprostaglandin dehydrogenase","type":"broad"},{"name":"type II 15-hydroxyprostaglandin dehydrogenase activity","type":"related"}],"termid":"GO:0047021"}


id: PR:Q9P6S4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- meu25 gene.","definition_xrefs":["UniProtKB:Q9P6S4","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic expression up-regulated protein 25 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC27.03","synonyms":[{"name":"Spom972h-meu25","type":"exact"}],"termid":"PR:Q9P6S4"}


id: GO:0032051
data:
  {"annotated_genes":["SJAG_00152","SJAG_02282"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76705,77469],"is_not":false,"summary":null,"term":"GO:0032051"}]},"cv_name":"molecular_function","definition":"Binding to a clathrin light chain.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"clathrin binding","termid":"GO:0030276"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00152":null,"SJAG_02282":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"clathrin light chain binding","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0032051","terms_by_termid":{"GO:0032051":null}}


id: PBO:0065182
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein S (beta) pseudogene","termid":"PBO:0065182"}


id: GO:1905860
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding.","definition_xrefs":["GOC:TermGenie","GO_REF:0000059","GOC:bc","PMID:7683668","GOC:aruk"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of heparan sulfate proteoglycan binding (obsolete GO:1905860)","synonyms":[{"name":"activation of heparan sulfate proteoglycan binding","type":"narrow"},{"name":"activation of heparin proteoglycan binding","type":"related"},{"name":"positive regulation of heparin proteoglycan binding","type":"related"},{"name":"up regulation of heparan sulfate proteoglycan binding","type":"exact"},{"name":"up regulation of heparin proteoglycan binding","type":"related"},{"name":"up-regulation of heparan sulfate proteoglycan binding","type":"exact"},{"name":"up-regulation of heparin proteoglycan binding","type":"related"},{"name":"upregulation of heparan sulfate proteoglycan binding","type":"exact"},{"name":"upregulation of heparin proteoglycan binding","type":"related"}],"termid":"GO:1905860"}


id: GO:0030292
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Stops, prevents or reduces the activity of a protein tyrosine kinase.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein kinase inhibitor activity","termid":"GO:0004860"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0004857"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0030234","GO:0004857","GO:0098772","GO:0140678","GO:0003674"],"is_obsolete":false,"name":"protein tyrosine kinase inhibitor activity","termid":"GO:0030292"}


id: GO:0075287
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of asexual sporulation resulting in formation of a cellular spore","termid":"GO:0043945"},{"relation_name":"is_a","term_name":"regulation of sporangiospore formation","termid":"GO:0075286"},{"relation_name":"positively_regulates","term_name":"sporangiospore formation","termid":"GO:0034300"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of sporangiospore formation","termid":"GO:0075287"}


id: MOD:01199
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-arginine residue to an N-heptosyl-L-arginine.","definition_xrefs":["Unimod:490#R"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heptosylated residue","termid":"MOD:00925"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"N-heptosyl-L-arginine","synonyms":[{"name":"Hep","type":"related"},{"name":"Heptose","type":"related"}],"termid":"MOD:01199"}


id: MONDO:0006032
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the urinary bladder.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urinary bladder disorder","termid":"MONDO:0006026"},{"relation_name":"is_a","term_name":"inflammatory disease","termid":"MONDO:0021166"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cystitis","secondary_identifiers":["SCTID:38822007","ICD9:595","ICD9:595.9","icd11.foundation:1181120673","NCIT:C26738","ICD9:595.89","UMLS:C0010692","DOID:1679","EFO:1000025","MEDGEN:8227","MESH:D003556"],"synonyms":[{"name":"bladder infection","type":"exact"},{"name":"inflammation of urinary bladder","type":"exact"},{"name":"urinary bladder inflammation","type":"exact"}],"termid":"MONDO:0006032","xrefs":{"Monarch":{"xref_id":"0006032"}}}


id: PBO:0076901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed 55","termid":"PBO:0076901"}


id: GO:0048746
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process whose specific outcome is the progression of smooth muscle fiber over time, from its formation to the mature structure.","definition_xrefs":["GOC:jid","GOC:lm","GOC:mtg_muscle","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete smooth muscle fiber development (obsolete GO:0048746)","synonyms":[{"name":"smooth muscle fiber development","type":"exact"},{"name":"smooth muscle fibre development","type":"exact"}],"termid":"GO:0048746"}


id: MONDO:0017998
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any neurodegeneration with brain iron accumulation in which the cause of the disease is a mutation in the PLA2G6 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete disorder of phospholipids, sphingolipids and fatty acids biosynthesis with central nervous system predominant involvement (obsolete MONDO:0018118)","termid":"MONDO:0018118"},{"relation_name":"excluded_subClassOf","term_name":"neurodegeneration with brain iron accumulation","termid":"MONDO:0018307"},{"relation_name":"is_a","term_name":"neurodegeneration with brain iron accumulation","termid":"MONDO:0018307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0002039","MONDO:0005066","MONDO:0005559"],"is_obsolete":false,"name":"PLA2G6-associated neurodegeneration","secondary_identifiers":["NORD:1302","GARD:12567","Orphanet:329303"],"synonyms":[{"name":"PLA2G6 neurodegeneration with brain iron accumulation","type":"exact"},{"name":"PLAN","type":"exact"},{"name":"neurodegeneration with brain iron accumulation caused by mutation in PLA2G6","type":"exact"}],"termid":"MONDO:0017998","xrefs":{"Monarch":{"xref_id":"0017998"}}}


id: MONDO:0008086
data:
  {"annotated_genes":["SJAG_04178"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86742],"is_not":false,"summary":null,"term":"MONDO:0008086"}]},"cv_name":"mondo","definition":"An axonal form of hereditary motor and sensory neuropathy distinguished by prominent early sensory loss and later positive sensory phenomena, caused by mutations in SPTLC1.","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary sensory and autonomic neuropathy type 1","termid":"MONDO:0018213"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04178":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005244","MONDO:0005066"],"is_obsolete":false,"name":"neuropathy, hereditary sensory and autonomic, type 1A","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0070152","GARD:15095","MEDGEN:1716450","OMIM:162400","UMLS:C5235211"],"synonyms":[{"name":"HSAN 1A","type":"related"},{"name":"HSAN1A","type":"exact"},{"name":"HSN 1A","type":"related"},{"name":"SPTLC1 hereditary sensory and autonomic neuropathy type 1","type":"exact"},{"name":"hereditary sensory and autonomic neuropathy type 1 caused by mutation in SPTLC1","type":"exact"},{"name":"hereditary sensory and autonomic neuropathy type 1A","type":"related"},{"name":"hereditary sensory and autonomic neuropathy type IA","type":"exact"},{"name":"neuropathy, hereditary sensory and autonomic, type IA","type":"related"},{"name":"neuropathy, hereditary sensory radicular, autosomal dominant, type 1A","type":"related"},{"name":"neuropathy, hereditary sensory, type 1A","type":"related"}],"termid":"MONDO:0008086","terms_by_termid":{"MONDO:0008086":null},"xrefs":{"Monarch":{"xref_id":"0008086"}}}


id: PBO:0090618
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DDHD family phospholipase","termid":"PBO:0090618"}


id: PBO:0040075
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arrestin domain containing 3","termid":"PBO:0040075"}


id: GO:0021846
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.","definition_xrefs":["GO_REF:0000021","GOC:cls","GOC:dph","GOC:jid","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neural precursor cell proliferation","termid":"GO:0061351"},{"relation_name":"part_of","term_name":"forebrain development","termid":"GO:0030900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell proliferation in forebrain","termid":"GO:0021846"}


id: PBO:0058443
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5008","termid":"PBO:0058443"}


id: PBO:0081121
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZFAT antisense RNA 1","termid":"PBO:0081121"}


id: PBO:0072733
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sphingosine-1-phosphate receptor 3","termid":"PBO:0072733"}


id: GO:0061452
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system neuron differentiation","termid":"GO:0021953"},{"relation_name":"part_of","term_name":"retrotrapezoid nucleus development","termid":"GO:0061451"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"retrotrapezoid nucleus neuron differentiation","termid":"GO:0061452"}


id: GO:0015180
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.","definition_xrefs":["GOC:jsg","GOC:mtg_transport","GOC:go_curators","ISBN:0198506732","GOC:mah","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-amino acid transmembrane transporter activity","termid":"GO:0015179"},{"relation_name":"is_a","term_name":"alanine transmembrane transporter activity","termid":"GO:0022858"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"L-alanine transmembrane transporter activity","synonyms":[{"name":"L-alanine transporter activity","type":"broad"}],"termid":"GO:0015180"}


id: GO:0004753
data:
  {"annotated_genes":["SJAG_02388","SJAG_01061"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[57285],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004754"},{"annotations":[109490],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004755"}]},"cv_name":"molecular_function","definition":"Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01061":null,"SJAG_02388":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"saccharopine dehydrogenase activity","references_by_uniquename":{"GO_REF:0000003":null,"GO_REF:0000107":null},"synonyms":[{"name":"lysine-2-oxoglutarate reductase activity","type":"related"},{"name":"lysine-ketoglutarate reductase activity","type":"related"}],"termid":"GO:0004753","terms_by_termid":{"GO:0004754":null,"GO:0004755":null}}


id: PBO:0065480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome activator subunit 1","termid":"PBO:0065480"}


id: GO:0018237
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Increases the activity of urease by promoting the incorporation of nickel into the active site.","definition_xrefs":["GOC:mah","PMID:16244137"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme activator activity","termid":"GO:0008047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140677"}],"interesting_parent_ids":["GO:0098772","GO:0140677","GO:0030234","GO:0003674"],"is_obsolete":false,"name":"urease activator activity","synonyms":[{"name":"urease activase activity","type":"exact"}],"termid":"GO:0018237"}


id: GO:0030401
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete transcription antiterminator activity (obsolete GO:0030401)","synonyms":[{"name":"transcription antiterminator activity","type":"exact"},{"name":"transcriptional antiterminator activity","type":"exact"}],"termid":"GO:0030401"}


id: GO:0009844
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.","definition_xrefs":["GOC:lr"],"gene_count":0,"genotype_count":0,"name":"obsolete germination (obsolete GO:0009844)","synonyms":[{"name":"germination","type":"exact"}],"termid":"GO:0009844"}


id: GO:0010397
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.","definition_xrefs":["GOC:tair_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide metabolic process","termid":"GO:0005976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"apiogalacturonan metabolic process","synonyms":[{"name":"apiogalacturonan metabolism","type":"exact"}],"termid":"GO:0010397"}


id: GO:0052165
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06","PMID:6870275"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated evasion of host immune response","termid":"GO:0042783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host phytoalexin production","secondary_identifiers":["GO:0052304","GO:0052549","PMID:28805743","GO:0052061","GO:0052378","GO:0052566"],"synonyms":[{"name":"evasion or tolerance by symbiont of host-produced phytoalexins","type":"exact"},{"name":"evasion or tolerance of phytoalexins","type":"exact"},{"name":"evasion or tolerance of phytoalexins produced by host in response to organism","type":"exact"},{"name":"host phytoalexin detoxification","type":"narrow"},{"name":"modulation by organism of phytoalexin production in other organism involved in symbiotic interaction","type":"narrow"},{"name":"modulation by symbiont of host phytoalexin production","type":"narrow"},{"name":"phytoalexin detoxification","type":"narrow"},{"name":"response to host phytoalexin production","type":"broad"},{"name":"response to phytoalexin production by other organism involved in symbiotic interaction","type":"broad"},{"name":"symbiont defense to host-produced phytoalexin","type":"exact"}],"termid":"GO:0052165"}


id: PBO:0076432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TATA-box binding protein associated factor 11 like 8","termid":"PBO:0076432"}


id: PBO:0086128
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for high temperature survival during stationary phase; not required for growth on nonfermentable carbon sources; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum","termid":"PBO:0086128"}


id: FYPO:0006320
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the increase in small deletions or duplications (\\\"replication slippage\\\") that normally results from processing arrested replication forks is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:29215009","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process during vegetative growth","termid":"FYPO:0001319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal replication slippage during replication fork processing","synonyms":[{"name":"normal replication slippage during replication fork processing during vegetative growth","type":"related"},{"name":"normal replication slippage during replication fork processing during vegetative growth during mitotic cell cycle","type":"related"}],"termid":"FYPO:0006320"}


id: GO:0034544
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3.","definition_xrefs":["UM-BBD_reactionID:r0810"],"gene_count":0,"genotype_count":0,"name":"obsolete trans-ACOHDA hydrolase activity (obsolete GO:0034544)","termid":"GO:0034544"}


id: PBO:0075270
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 18 pseudogene 23","termid":"PBO:0075270"}


id: PBO:0050147
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 3 pseudogene 3","termid":"PBO:0050147"}


id: PBO:0052486
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kelch like family member 1","termid":"PBO:0052486"}


id: FYPO:0005141
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is decreased.","definition_xrefs":["PMID:15238514","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiotic recombination double-strand break repair","termid":"FYPO:0005139"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000293"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0000293","FYPO:0001985","FYPO:0000631","FYPO:0000298"],"is_obsolete":false,"name":"decreased meiotic recombination double-strand break repair","synonyms":[{"name":"decreased DSB repair involved in reciprocal meiotic recombination","type":"exact"},{"name":"decreased double-strand break repair during meiotic recombination","type":"exact"},{"name":"decreased double-strand break repair involved in reciprocal meiotic recombination","type":"exact"},{"name":"reduced meiotic recombination double-strand break repair","type":"exact"}],"termid":"FYPO:0005141"}


id: MONDO:0021039
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A spectrum of malignant tumors arising from the soft tissues, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms.","definition_xrefs":["NCIT:C27293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Ewing sarcoma/peripheral primitive neuroectodermal tumor","termid":"MONDO:0021038"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor","secondary_identifiers":["DOID:4985","EFO:1000250","MEDGEN:232170","UMLS:C1333514"],"synonyms":[{"name":"extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumor","type":"exact"},{"name":"extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumour","type":"exact"},{"name":"extraosseous Ewing's sarcoma/peripheral primitive neuroectodermal tumor","type":"exact"},{"name":"extraosseous Ewing's sarcoma/peripheral primitive neuroectodermal tumour","type":"exact"},{"name":"extraosseous Ewing's tumor","type":"related"},{"name":"extraosseous Ewing's tumour","type":"related"},{"name":"extraosseous Ewings sarcoma-primitive neuroepithelial tumor","type":"exact"},{"name":"extraosseous Ewings sarcoma-primitive neuroepithelial tumour","type":"exact"},{"name":"extraskeletal Ewing sarcoma/peripheral primitive neuroectodermal tumor","type":"exact"}],"termid":"MONDO:0021039","xrefs":{"Monarch":{"xref_id":"0021039"}}}


id: PBO:0084792
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial protein; required for normal mitochondrial morphology and inheritance; component of the mitochondria-ER-cortex-anchor (MECA); interacts with Num1p to link the ER and mitochondria at the cell cortex; proposed involvement in the formation of Dnm1p and Num1p-containing cortical anchor complexes that promote mitochondrial fission","termid":"PBO:0084792"}


id: PBO:0084531
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; relocalizes to the cytosol in response to hypoxia; isy1 syf2 cells have defective spindles activiating cell cycle arrest","termid":"PBO:0084531"}


id: PBO:0029157
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_cellular_trehalose_level_in_spore","termid":"PBO:0029157"}


id: GO:0034935
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+.","definition_xrefs":["UM-BBD_reactionID:r0957"],"gene_count":0,"genotype_count":0,"name":"obsolete tetrachlorobenzene dioxygenase activity (obsolete GO:0034935)","termid":"GO:0034935"}


id: PBO:0030982
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H3-K9_dimethylation_at_centromere_inner_repeat","termid":"PBO:0030982"}


id: GO:0061687
data:
  {"annotated_genes":["SJAG_04516","SJAG_00988","SJAG_04953","SJAG_01216","SJAG_01344","SJAG_02599","SJAG_01351","SJAG_00141","SJAG_02515","SJAG_01078","SJAG_01973","SJAG_03497","SJAG_04823","SJAG_01803","SJAG_01199"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[96809,70628,117998,108228,93107,96847],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098849"},{"annotations":[113530],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140114"},{"annotations":[108630,94987,117163,118085,99802,104846],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061692"},{"annotations":[70627],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010273"},{"annotations":[93563,93564],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010312"}]},"cv_name":"biological_process","definition":"Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.","definition_xrefs":["GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detoxification","termid":"GO:0098754"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00141":null,"SJAG_00988":null,"SJAG_01078":null,"SJAG_01199":null,"SJAG_01216":null,"SJAG_01344":null,"SJAG_01351":null,"SJAG_01803":null,"SJAG_01973":null,"SJAG_02515":null,"SJAG_02599":null,"SJAG_03497":null,"SJAG_04516":null,"SJAG_04823":null,"SJAG_04953":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0098754"}],"interesting_parent_ids":["GO:0008150","GO:0098754"],"is_obsolete":false,"name":"detoxification of inorganic compound","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0061687","terms_by_termid":{"GO:0010273":null,"GO:0010312":null,"GO:0061692":null,"GO:0098849":null,"GO:0140114":null}}


id: PBO:0000759
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gene structure uopdated","termid":"PBO:0000759"}


id: MONDO:0010175
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"van Bogaert-Hozay syndrome","secondary_identifiers":["MESH:C536526","MEDGEN:341263","UMLS:C1848598","OMIM:277150"],"synonyms":[{"name":"A familial form of acro-osteolysis associated with a mild intellectual disability, skin atrophy, facial dysmorphism, and ocular defects","type":"related"},{"name":"A familial form of acro-osteolysis associated with a mild mental retardation, skin atrophy, facial dysmorphism, and ocular defects","type":"related"},{"name":"Hozay's syndrome","type":"related"},{"name":"Hozay’s syndrome","type":"related"},{"name":"acro-osteolysis-facial dysplasia syndrome","type":"related"},{"name":"van Bogaert-Hozay syndrome","type":"exact"}],"termid":"MONDO:0010175","xrefs":{"Monarch":{"xref_id":"0010175"}}}


id: GO:0110032
data:
  {"annotated_genes":["SJAG_04332"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73349],"is_not":false,"summary":null,"term":"GO:0110032"}]},"cv_name":"biological_process","definition":"Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.","definition_xrefs":["PMID:25492408","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of G2/MI transition of meiotic cell cycle","termid":"GO:0110030"},{"relation_name":"is_a","term_name":"positive regulation of meiotic cell cycle phase transition","termid":"GO:1901995"},{"relation_name":"is_a","term_name":"positive regulation of cell cycle G2/M phase transition","termid":"GO:1902751"},{"relation_name":"positively_regulates","term_name":"G2/MI transition of meiotic cell cycle","termid":"GO:0008315"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04332":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"positive regulation of G2/MI transition of meiotic cell cycle","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0110032","terms_by_termid":{"GO:0110032":null}}


id: PBO:0027840
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_viability_in_stationary_phase_during_nitrogen_limitation","termid":"PBO:0027840"}


id: PBO:0050095
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 5","termid":"PBO:0050095"}


id: GO:1905138
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.","definition_xrefs":["PMID:24711378","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of viral life cycle","termid":"GO:1903902"},{"relation_name":"is_a","term_name":"regulation of viral DNA genome packaging via site-specific sequence recognition","termid":"GO:1905137"},{"relation_name":"positively_regulates","term_name":"viral DNA genome packaging via site-specific sequence recognition","termid":"GO:0098035"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of viral DNA genome packaging via site-specific sequence recognition","synonyms":[{"name":"activation of viral DNA genome packaging via site-specific sequence recognition","type":"narrow"},{"name":"up regulation of viral DNA genome packaging via site-specific sequence recognition","type":"exact"},{"name":"up-regulation of viral DNA genome packaging via site-specific sequence recognition","type":"exact"},{"name":"upregulation of viral DNA genome packaging via site-specific sequence recognition","type":"exact"}],"termid":"GO:1905138"}


id: GO:0070622
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.","definition_xrefs":["PMID:8940155","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase complex, transferring phosphorus-containing groups","termid":"GO:0061695"},{"relation_name":"part_of","term_name":"lysosome","termid":"GO:0005764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005773"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005773","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex","synonyms":[{"name":"N-acetylglucosamine-1-phosphotransferase complex","type":"related"},{"name":"UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex","type":"exact"}],"termid":"GO:0070622"}


id: PBO:0082304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Asparagine synthetase; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway; ASN2 has a paralog, ASN1, that arose from the whole genome duplication","termid":"PBO:0082304"}


id: PBO:0077365
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 106A","termid":"PBO:0077365"}


id: MONDO:1010082
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Evans syndrome that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune thrombocytopenia, non-human animal","termid":"MONDO:1010069"},{"relation_name":"is_a","term_name":"syndromic disease, non-human animal","termid":"MONDO:1011360"},{"relation_name":"is_a","term_name":"autoimmune hemolytic anemia, non-human animal","termid":"MONDO:1011406"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Evans syndrome, non-human animal","secondary_identifiers":["OMIA:001286"],"termid":"MONDO:1010082","xrefs":{"Monarch":{"xref_id":"1010082"}}}


id: PBO:0069547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 818, pseudogene","termid":"PBO:0069547"}


id: GO:0031490
data:
  {"annotated_genes":["SJAG_04879","SJAG_03354","SJAG_01827","SJAG_00861","SJAG_03944","SJAG_05333","SJAG_00164","SJAG_02815","SJAG_00698","SJAG_00585"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70102,73751,76866,79562,110920],"is_not":false,"summary":null,"term":"GO:0031490"},{"annotations":[106727,115159,99384,108928],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043035"},{"annotations":[111676],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140585"}]},"cv_name":"molecular_function","definition":"Binding to DNA that is assembled into chromatin.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA binding","termid":"GO:0003677"},{"relation_name":"is_a","term_name":"chromatin binding","termid":"GO:0003682"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00164":null,"SJAG_00585":null,"SJAG_00698":null,"SJAG_00861":null,"SJAG_01827":null,"SJAG_02815":null,"SJAG_03354":null,"SJAG_03944":null,"SJAG_04879":null,"SJAG_05333":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003677"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0003677","GO:0005488"],"is_obsolete":false,"name":"chromatin DNA binding","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0031490","terms_by_termid":{"GO:0031490":null,"GO:0043035":null,"GO:0140585":null}}


id: GO:0097379
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.","definition_xrefs":["GOC:yaf","PMID:19545367"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anterior/posterior axon guidance","termid":"GO:0033564"},{"relation_name":"is_a","term_name":"dorsal spinal cord interneuron axon guidance","termid":"GO:0097378"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dorsal spinal cord interneuron posterior axon guidance","synonyms":[{"name":"dorsal interneuron caudal axon projection","type":"related"}],"termid":"GO:0097379"}


id: PBO:0050118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 28","termid":"PBO:0050118"}


id: PBO:0038726
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin gamma 1 pseudogene 21","termid":"PBO:0038726"}


id: PBO:0045031
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DIS3 like 3'-5' exoribonuclease 2 pseudogene 1","termid":"PBO:0045031"}


id: PBO:0091016
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CTP synthase Cts1","termid":"PBO:0091016"}


id: GO:2000701
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.","definition_xrefs":["GOC:obol","GOC:yaf","GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glial cell-derived neurotrophic factor receptor signaling pathway","termid":"GO:0035860"},{"relation_name":"part_of","term_name":"ureteric bud formation","termid":"GO:0060676"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation","synonyms":[{"name":"GDNF receptor signaling pathway of ureteric bud formation","type":"exact"},{"name":"glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation","type":"exact"},{"name":"glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation","type":"exact"},{"name":"glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation","type":"exact"},{"name":"glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation","type":"exact"}],"termid":"GO:2000701"}


id: PR:O42972
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC20F10.02c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42972"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UPF0588 membrane protein C20F10.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC20F10.02c","synonyms":[{"name":"Spom972h-SPBC20F10.02c","type":"exact"}],"termid":"PR:O42972"}


id: GO:0021557
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.","definition_xrefs":["GO_REF:0000021","GOC:cls","GOC:dgh","ISBN:0838580343","GOC:jid","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve development","termid":"GO:0021545"},{"relation_name":"part_of","term_name":"preganglionic parasympathetic fiber development","termid":"GO:0021783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"oculomotor nerve development","synonyms":[{"name":"CN III development","type":"related"},{"name":"cranial nerve 3 development","type":"exact"},{"name":"cranial nerve III development","type":"exact"}],"termid":"GO:0021557"}


id: GO:0140110
data:
  {"annotated_genes":["SJAG_00164","SJAG_02691","SJAG_00073","SJAG_04381","SJAG_04092","SJAG_04036","SJAG_03289","SJAG_04191","SJAG_00540","SJAG_05203","SJAG_00156","SJAG_00037","SJAG_01157","SJAG_03346","SJAG_02052","SJAG_03481","SJAG_04749","SJAG_03918","SJAG_02956","SJAG_02066","SJAG_01711","SJAG_00909","SJAG_04389","SJAG_02922","SJAG_03879","SJAG_05006","SJAG_01916","SJAG_04388","SJAG_04421","SJAG_04647","SJAG_00269","SJAG_06576","SJAG_02752","SJAG_04584","SJAG_03590","SJAG_02149","SJAG_02326","SJAG_06599","SJAG_03388","SJAG_00342","SJAG_00664","SJAG_00904","SJAG_01694","SJAG_04213","SJAG_03664","SJAG_03241","SJAG_03911","SJAG_01952","SJAG_01707","SJAG_03519","SJAG_00441","SJAG_03945","SJAG_02831","SJAG_02709","SJAG_04205","SJAG_04009","SJAG_01930","SJAG_03776","SJAG_01658","SJAG_01926","SJAG_02138","SJAG_03143","SJAG_01243","SJAG_00987","SJAG_00693","SJAG_03924","SJAG_02773","SJAG_02391","SJAG_03845","SJAG_02329","SJAG_02938","SJAG_06638","SJAG_05247","SJAG_03484","SJAG_04921","SJAG_01804","SJAG_03622","SJAG_00861","SJAG_04186","SJAG_02238","SJAG_01441","SJAG_00266","SJAG_04274","SJAG_04813","SJAG_02849","SJAG_02393","SJAG_04099","SJAG_01771","SJAG_04353","SJAG_03735","SJAG_02474","SJAG_02927","SJAG_02385","SJAG_02218","SJAG_02165","SJAG_01728","SJAG_02846","SJAG_03538","SJAG_01725","SJAG_00386","SJAG_02048","SJAG_01403","SJAG_01778","SJAG_00584","SJAG_02252","SJAG_03441","SJAG_01113","SJAG_02730","SJAG_04373","SJAG_02255","SJAG_03981","SJAG_00634","SJAG_02541","SJAG_00792","SJAG_00483","SJAG_03599","SJAG_04607","SJAG_03668","SJAG_01307","SJAG_04249","SJAG_02196","SJAG_01111","SJAG_00802","SJAG_01062","SJAG_04705","SJAG_00979","SJAG_02569","SJAG_03473","SJAG_03573","SJAG_04396","SJAG_03211","SJAG_05288","SJAG_02406","SJAG_05343","SJAG_00210","SJAG_02810","SJAG_01475","SJAG_02472","SJAG_04839","SJAG_00290","SJAG_00163","SJAG_00641","SJAG_00698","SJAG_01343","SJAG_02311","SJAG_00087","SJAG_01740","SJAG_00613","SJAG_02458","SJAG_00297","SJAG_00822","SJAG_02097","SJAG_00184","SJAG_00926","SJAG_02898","SJAG_01583","SJAG_02671","SJAG_05234","SJAG_04613","SJAG_03183","SJAG_04374","SJAG_05341","SJAG_04820","SJAG_00304","SJAG_03752","SJAG_01532","SJAG_00124","SJAG_02401","SJAG_01193","SJAG_03107","SJAG_04712","SJAG_03627","SJAG_00809","SJAG_02990","SJAG_04855","SJAG_05337","SJAG_02494","SJAG_05153","SJAG_03527"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[75685],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001216"},{"annotations":[88581,57392,98221,104242,68374,96079,107773,102077,79873,115867,77213,99307,96373,88828,92552,75555,105913,72244,108842,61099,111675,116263,113475,87384,110519,75636,88245,87821,100302,79357,74681,91710,105645,97092,107375,108605,114374,95484,117284,87750,74712,89253,77278],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001228"},{"annotations":[68114,72531,66966,71861],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003700"},{"annotations":[57304,60809,66200,113199,68286,64751,72397,96855,102495,58095,109149,72813,101846,57926,108433,114626,60435,62694,62714,58727,97169,69388,73237,58326,59880,69039,74499,61786,59001,60295,76776,68759],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000981"},{"annotations":[104244,93101,115868,94519,93858,108606,80235,106054],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001227"},{"annotations":[96185],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106250"},{"annotations":[87207,97979],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034246"},{"annotations":[78405,76865,118888,106039,118728,105576,94138,98829,90474,108031,112088,98378,114098,102655,101754,106860,107214,100292,117365,103161,103408,77604,61957,73336,103210,93296,57798,61980,78108,95954,106173,89074,71394,93883,106704,90158,103469,107128,88901,106531,112770,117412,75259,74858,75125,91213,88284,99099,94876,102964,95656,118889,94244,114526,108547,95175,97620,108521,98477],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003713"},{"annotations":[95686,71674,77581,79440,76579,77647,77883,88584,77145],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003712"},{"annotations":[103752,78918,91051,93041,97017,104053,104114,106532,98688,109140,73482,111885,93003,70053,103993,73000,106804,75175],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003714"},{"annotations":[99737,92444,105310,112977,72227,91773,117732,93746,106625,107688],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003711"}]},"cv_name":"molecular_function","definition":"A molecular function that controls the rate, timing and/or magnitude of gene transcription. 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id: PBO:0062840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oligosaccharyltransferase complex subunit pseudogene 6","termid":"PBO:0062840"}


id: FYPO:0002134
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which an interaction between a protein and RNA is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein-RNA interaction","termid":"FYPO:0002132"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0002131"}],"interesting_parent_ids":["FYPO:0002131","FYPO:0000652","FYPO:0001985","FYPO:0000707"],"is_obsolete":false,"name":"decreased protein-RNA interaction","synonyms":[{"name":"decreased RNA binding","type":"exact"},{"name":"decreased RNA-protein interaction","type":"exact"},{"name":"reduced RNA binding","type":"exact"}],"termid":"FYPO:0002134"}


id: PBO:0067043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 62, pseudogene","termid":"PBO:0067043"}


id: FYPO:0006100
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased, and some of the protein is present in the nucleus instead.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"protein mislocalized to nucleus during vegetative growth","termid":"FYPO:0000784"},{"relation_name":"is_a","term_name":"protein mislocalized to nucleus during vegetative growth","termid":"FYPO:0000784"},{"relation_name":"is_a","term_name":"decreased protein localization to cytoplasm","termid":"FYPO:0006099"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"decreased protein localization to cytoplasm, with protein mislocalized to nucleus","synonyms":[{"name":"decreased protein localisation to cytoplasm, with protein mislocalised to nucleus","type":"exact"},{"name":"decreased protein localization in cytoplasm, with protein mislocalized to nucleus","type":"exact"},{"name":"decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during vegetative growth","type":"exact"},{"name":"reduced protein localization to cytoplasm, with protein mislocalized to nucleus","type":"exact"}],"termid":"FYPO:0006100"}


id: GO:0015504
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).","definition_xrefs":["TC:2.A.39.1.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytosine transmembrane transporter activity","termid":"GO:0015209"},{"relation_name":"is_a","term_name":"solute:proton symporter activity","termid":"GO:0015295"},{"relation_name":"is_a","term_name":"nucleobase:monoatomic cation symporter activity","termid":"GO:0015391"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"cytosine:proton symporter activity","synonyms":[{"name":"cytosine permease activity","type":"related"},{"name":"cytosine:hydrogen ion symporter activity","type":"exact"}],"termid":"GO:0015504"}


id: GO:0019290
data:
  {"annotated_genes":["SJAG_04031","SJAG_00792","SJAG_00469","SJAG_04032"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[93906,93899,105197],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031169"},{"annotations":[93854],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1905569"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.","definition_xrefs":["PMID:20376388"],"direct_ancestors":[{"relation_name":"is_a","term_name":"siderophore metabolic process","termid":"GO:0009237"},{"relation_name":"is_a","term_name":"nonribosomal peptide biosynthetic process","termid":"GO:0019184"},{"relation_name":"is_a","term_name":"secondary metabolite biosynthetic process","termid":"GO:0044550"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00469":null,"SJAG_00792":null,"SJAG_04031":null,"SJAG_04032":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"siderophore biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0031178","GO:0031180"],"synonyms":[{"name":"siderochrome biosynthesis","type":"narrow"},{"name":"siderochrome biosynthetic process","type":"narrow"},{"name":"siderophore anabolism","type":"exact"},{"name":"siderophore biosynthesis","type":"exact"},{"name":"siderophore biosynthetic process, peptide formation","type":"narrow"},{"name":"siderophore biosynthetic process, peptide modification","type":"narrow"},{"name":"siderophore formation","type":"exact"},{"name":"siderophore synthesis","type":"exact"}],"termid":"GO:0019290","terms_by_termid":{"GO:0031169":null,"GO:1905569":null}}


id: GO:0008890
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA.","definition_xrefs":["EC:2.3.1.29","RHEA:20736"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C-acetyltransferase activity","termid":"GO:0016453"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016746","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"glycine C-acetyltransferase activity","secondary_identifiers":["MetaCyc:AKBLIG-RXN","KEGG_REACTION:R00371"],"synonyms":[{"name":"glycine acetyltransferase activity","type":"related"}],"termid":"GO:0008890"}


id: PBO:0058439
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5003","termid":"PBO:0058439"}


id: PBO:0051218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 7-4-1","termid":"PBO:0051218"}


id: GO:0110147
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.","definition_xrefs":["GOC:al","PMID:24115911"],"gene_count":0,"genotype_count":0,"name":"obsolete protein maturation by nickel ion transfer (obsolete GO:0110147)","termid":"GO:0110147"}


id: MONDO:0800176
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Local and/or systemic toxicity resulting from a bite from a black widow spider (Latrodectus species).","direct_ancestors":[{"relation_name":"is_a","term_name":"poisoning","termid":"MONDO:0029000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"black widow spider envenomation","secondary_identifiers":["SCTID:217666004"],"synonyms":[{"name":"black widow envenomation","type":"exact"},{"name":"latrodectism","type":"exact"},{"name":"poisoning caused by black widow venom","type":"exact"},{"name":"poisoning due to black widow spider","type":"exact"},{"name":"toxic effect of venom of black widow","type":"exact"}],"termid":"MONDO:0800176","xrefs":{"Monarch":{"xref_id":"0800176"}}}


id: GO:0036516
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.","definition_xrefs":["PMID:21106844","GOC:bf","GOC:PARL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemoattraction of axon","termid":"GO:0061642"},{"relation_name":"part_of","term_name":"dopaminergic neuron axon guidance","termid":"GO:0036514"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chemoattraction of dopaminergic neuron axon","synonyms":[{"name":"chemoattraction of DA axon","type":"exact"},{"name":"chemoattraction of dopaminergic axon","type":"exact"}],"termid":"GO:0036516"}


id: PBO:0043633
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COPI coat complex subunit epsilon","termid":"PBO:0043633"}


id: PBO:0042650
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDYL antisense RNA 1","termid":"PBO:0042650"}


id: PBO:0012825
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-removed_by","termid":"PBO:0012825"}


id: GO:0019287
data:
  {"annotated_genes":["SJAG_03715","SJAG_04865","SJAG_01474","SJAG_02380","SJAG_01187","SJAG_03349"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[74040,77000,79796,114696],"is_not":false,"summary":null,"term":"GO:0019287"},{"annotations":[111166,115272],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:2001211"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.","definition_xrefs":["MetaCyc:PWY-922","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetyl-CoA metabolic process","termid":"GO:0006084"},{"relation_name":"is_a","term_name":"isopentenyl diphosphate biosynthetic process","termid":"GO:0009240"}],"gene_count":6,"genes_by_uniquename":{"SJAG_01187":null,"SJAG_01474":null,"SJAG_02380":null,"SJAG_03349":null,"SJAG_03715":null,"SJAG_04865":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"part_of","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0044281","GO:0006790","GO:0055086","GO:0008150","GO:0006629"],"is_obsolete":false,"name":"isopentenyl diphosphate biosynthetic process, mevalonate pathway","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"Ac-MVA pathway","type":"exact"},{"name":"acetate-mevalonate pathway","type":"exact"},{"name":"isopentenyl diphosphate anabolism, mevalonate pathway","type":"exact"},{"name":"isopentenyl diphosphate biosynthetic process via mevalonate","type":"exact"},{"name":"isopentenyl diphosphate formation, mevalonate pathway","type":"exact"},{"name":"isopentenyl diphosphate synthesis, mevalonate pathway","type":"exact"}],"termid":"GO:0019287","terms_by_termid":{"GO:0019287":null,"GO:2001211":null}}


id: PBO:0076348
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptotagmin 14 pseudogene 1","termid":"PBO:0076348"}


id: PBO:0043897
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cysteine rich protein 1 pseudogene 4","termid":"PBO:0043897"}


id: GO:0051691
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete cellular oligosaccharide metabolic process (obsolete GO:0051691)","synonyms":[{"name":"cellular oligosaccharide metabolism","type":"exact"}],"termid":"GO:0051691"}


id: PBO:0064046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 80","termid":"PBO:0064046"}


id: GO:0019333
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen.","definition_xrefs":["MetaCyc:DENITRIFICATION-PWY"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nitrogen cycle metabolic process","termid":"GO:0071941"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0071941"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0071941","GO:0008150"],"is_obsolete":false,"name":"denitrification pathway","termid":"GO:0019333"}


id: PBO:0050687
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 8 pseudogene 14","termid":"PBO:0050687"}


id: GO:1902381
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving 11-oxo-beta-amyrin.","definition_xrefs":["PMID:22128119","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pentacyclic triterpenoid metabolic process","termid":"GO:0019742"},{"relation_name":"is_a","term_name":"ketone metabolic process","termid":"GO:0042180"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"11-oxo-beta-amyrin metabolic process","synonyms":[{"name":"11-oxo-beta-amyrin metabolism","type":"exact"}],"termid":"GO:1902381"}


id: MONDO:1011708
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hematologic disorder, non-human animal","termid":"MONDO:1011319"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dyserythropoietic anemia and myopathy syndrome, non-human animal","secondary_identifiers":["OMIA:002564"],"termid":"MONDO:1011708","xrefs":{"Monarch":{"xref_id":"1011708"}}}


id: GO:0003838
data:
  {"annotated_genes":["SJAG_03531"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76116],"is_not":false,"summary":null,"term":"GO:0003838"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + zymosterol = fecosterol + H+ + S-adenosyl-L-homocysteine.","definition_xrefs":["RHEA:21128"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C-methyltransferase activity","termid":"GO:0008169"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03531":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016741","GO:0016740"],"is_obsolete":false,"name":"sterol 24-C-methyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:RXN3O-178","GO:0102101","EC:2.1.1.41"],"synonyms":[{"name":"24-sterol C-methyltransferase activity","type":"related"},{"name":"S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity","type":"related"},{"name":"S-adenosyl-4-methionine:sterol delta24-methyltransferase activity","type":"related"},{"name":"S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity","type":"related"},{"name":"S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity","type":"related"},{"name":"S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity","type":"related"},{"name":"SMT1 activity","type":"narrow"},{"name":"delta(24)-methyltransferase activity","type":"related"},{"name":"delta(24)-sterol C-methyltransferase activity","type":"exact"},{"name":"delta(24)-sterol methyltransferase activity","type":"related"},{"name":"delta24-methyltransferase activity","type":"related"},{"name":"delta24-sterol methyltransferase activity","type":"related"},{"name":"phytosterol methyltransferase activity","type":"narrow"},{"name":"sterol 24C methyltransferase activity","type":"exact"},{"name":"zymosterol-24-methyltransferase activity","type":"narrow"}],"termid":"GO:0003838","terms_by_termid":{"GO:0003838":null}}


id: MONDO:0001618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"balanitis","termid":"MONDO:0006672"},{"relation_name":"is_a","term_name":"posthitis","termid":"MONDO:0021164"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"balanoposthitis","secondary_identifiers":["icd11.foundation:1742248014","ICD9:607.1","ICD10CM:N47.6","MEDGEN:507475","DOID:13031","SCTID:46090001","UMLS:C0004691"],"termid":"MONDO:0001618","xrefs":{"Monarch":{"xref_id":"0001618"}}}


id: MONDO:0012792
data:
  {"annotated_genes":["SJAG_00885"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86120],"is_not":false,"summary":null,"term":"MONDO:0012792"}]},"cv_name":"mondo","definition":"Any mitochondrial DNA depletion syndrome in which the cause of the disease is a mutation in the RRM2B gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial DNA depletion syndrome, encephalomyopathic form","termid":"MONDO:0016796"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00885":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"mitochondrial DNA depletion syndrome 8a","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C2749861","Orphanet:255235","MEDGEN:412815","GARD:13200","OMIM:612075","DOID:0080127","SCTID:765100000","DOID:0070331"],"synonyms":[{"name":"MTDPS8A","type":"related"},{"name":"Mngie, Rrm2B-related","type":"related"},{"name":"RRM2B mitochondrial DNA depletion syndrome","type":"exact"},{"name":"RRM2B-related mitochondrial DNA depletion syndrome","type":"related"},{"name":"encephalomyopathic type with renal tubulopathy","type":"related"},{"name":"mitochondrial DNA depletion syndrome 8A (encephalomyopathic type with renal tubulopathy)","type":"related"},{"name":"mitochondrial DNA depletion syndrome 8B (Mngie type)","type":"related"},{"name":"mitochondrial DNA depletion syndrome caused by mutation in RRM2B","type":"exact"},{"name":"mitochondrial DNA depletion syndrome type 8a","type":"exact"},{"name":"mitochondrial DNA depletion syndrome, encephalomyopathic form with renal tubulopathy","type":"related"},{"name":"mitochondrial DNA depletion syndrome, encephalomyopathic, with renal tubulopathy, autosomal recessive","type":"related"},{"name":"mitochondrial neurogastrointestinal encephalopathy syndrome, Rrm2B-related","type":"related"},{"name":"mtDNA depletion syndrome, encephalomyopathic form with renal tubulopathy","type":"exact"}],"termid":"MONDO:0012792","terms_by_termid":{"MONDO:0012792":null},"xrefs":{"Monarch":{"xref_id":"0012792"}}}


id: PBO:0064037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 71","termid":"PBO:0064037"}


id: PBO:0113457
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of nuclear RNase P; nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits; increases the activity and thermal stability of the complex, along with Pop2p; protein abundance increases in response to DNA replication stress","termid":"PBO:0113457"}


id: PBO:0039577
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and sterile alpha motif domain containing 6","termid":"PBO:0039577"}


id: PBO:0026930
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_protein_complex_composition","termid":"PBO:0026930"}


id: PBO:0034506
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_frequency_of_meiotic_crossover_associated_with_gene_conversion","termid":"PBO:0034506"}


id: PATO:0001487
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A time quality inhering in a bearer by virtue of the bearer's growing old; aging.","definition_xrefs":["answers.com:answers.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"age","termid":"PATO:0000011"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"senescent","termid":"PATO:0001487"}


id: GO:0033921
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.","definition_xrefs":["EC:3.2.1.87"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactosidase activity","termid":"GO:0015925"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016798","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"capsular-polysaccharide endo-1,3-alpha-galactosidase activity","secondary_identifiers":["MetaCyc:3.2.1.87-RXN"],"synonyms":[{"name":"aerobacter-capsular-polysaccharide galactohydrolase activity","type":"related"},{"name":"capsular polysaccharide galactohydrolase activity","type":"related"},{"name":"polysaccharide depolymerase activity","type":"related"}],"termid":"GO:0033921"}


id: GO:0075270
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of spore-bearing organ development","termid":"GO:0075262"},{"relation_name":"is_a","term_name":"regulation of aecium development","termid":"GO:0075268"},{"relation_name":"negatively_regulates","term_name":"aecium development","termid":"GO:0075267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of aecium development","termid":"GO:0075270"}


id: PBO:0054518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1918","termid":"PBO:0054518"}


id: GO:0018415
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.","definition_xrefs":["RESID:AA0292"],"gene_count":0,"genotype_count":0,"name":"obsolete iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide (obsolete GO:0018415)","synonyms":[{"name":"iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide","type":"exact"}],"termid":"GO:0018415"}


id: MONDO:0009226
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any fibrochondrogenesis in which the cause of the disease is a mutation in the COL11A1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fibrochondrogenesis","termid":"MONDO:0016068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"fibrochondrogenesis 1","secondary_identifiers":["DOID:0080672","MEDGEN:479768","UMLS:C3278138","OMIM:228520"],"synonyms":[{"name":"COL11A1 fibrochondrogenesis","type":"exact"},{"name":"FBCG1","type":"related"},{"name":"fibrochondrogenesis 1","type":"exact"},{"name":"fibrochondrogenesis caused by mutation in COL11A1","type":"exact"},{"name":"fibrochondrogenesis type 1","type":"exact"}],"termid":"MONDO:0009226","xrefs":{"Monarch":{"xref_id":"0009226"}}}


id: _global:existence_starts_and_ends_during
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)","direct_ancestors":[{"relation_name":"is_a","term_name":"existence_ends_during","termid":"_global:existence_ends_during"},{"relation_name":"is_a","term_name":"existence_starts_during","termid":"_global:existence_starts_during"},{"relation_name":"is_a","term_name":"go_annotation_extension_relation","termid":"_global:go_annotation_extension_relation"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"existence_starts_and_ends_during","secondary_identifiers":["RO:0002491"],"synonyms":[{"name":"exists during","type":"exact"}],"termid":"_global:existence_starts_and_ends_during"}


id: PBO:0044141
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CTBP2 pseudogene 7","termid":"PBO:0044141"}


id: GO:0051245
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the rate of the cellular defense response.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular defense response","termid":"GO:0010185"},{"relation_name":"is_a","term_name":"negative regulation of defense response","termid":"GO:0031348"},{"relation_name":"negatively_regulates","term_name":"cellular defense response","termid":"GO:0006968"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cellular defense response","synonyms":[{"name":"down regulation of cellular defense response","type":"exact"},{"name":"down-regulation of cellular defense response","type":"exact"},{"name":"downregulation of cellular defense response","type":"exact"},{"name":"inhibition of cellular defense response","type":"narrow"},{"name":"negative regulation of cellular defence response","type":"exact"}],"termid":"GO:0051245"}


id: MONDO:1010593
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hyperparathyroidism that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hyperparathyroidism, non-human animal","termid":"MONDO:1010054"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperparathyroidism, horse","secondary_identifiers":["OMIA:000508-9796"],"termid":"MONDO:1010593","xrefs":{"Monarch":{"xref_id":"1010593"}}}


id: GO:0003259
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardioblast migration","termid":"GO:0003260"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardioblast anterior-lateral migration","termid":"GO:0003259"}


id: PBO:0058896
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 12114","termid":"PBO:0058896"}


id: PBO:0083152
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps ORF SEC6/YIL068C","termid":"PBO:0083152"}


id: GO:0052386
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A type of cell wall modification in which the cell wall is reinforced and made thicker.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell wall modification","termid":"GO:0042545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0071554"}],"interesting_parent_ids":["GO:0008150","GO:0071554"],"is_obsolete":false,"name":"cell wall thickening","termid":"GO:0052386"}


id: PBO:0091096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Dhm2","termid":"PBO:0091096"}


id: PBO:0001248
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.4.24.-","termid":"PBO:0001248"}


id: PBO:0060386
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myocardial zonula adherens protein","termid":"PBO:0060386"}


id: PBO:0050698
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HSPA12A antisense RNA 1","termid":"PBO:0050698"}


id: GO:0001109
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.","definition_xrefs":["GOC:txnOH","PMID:18280161","PMID:15020047"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA biosynthetic process","termid":"GO:0032774"},{"relation_name":"part_of","term_name":"DNA-templated transcription","termid":"GO:0006351"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006351"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467","GO:0006351"],"is_obsolete":false,"name":"promoter clearance during DNA-templated transcription","secondary_identifiers":["GO:0001122"],"synonyms":[{"name":"promoter clearance during DNA-dependent transcription","type":"exact"},{"name":"promoter clearance from bacterial-type RNA polymerase promoter","type":"narrow"},{"name":"promoter escape","type":"broad"}],"termid":"GO:0001109"}


id: MONDO:0044337
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm characterized by the presence of atypical mesenchymal-stromal cells. Representative examples include endometrial stromal sarcoma and prostate stromal sarcoma.","definition_xrefs":["NCIT:C6926"],"direct_ancestors":[{"relation_name":"is_a","term_name":"soft tissue sarcoma","termid":"MONDO:0018078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"stromal sarcoma","secondary_identifiers":["UMLS:C1370723","MEDGEN:235091","ICDO:8935/3"],"synonyms":[{"name":"stromal sarcoma","type":"exact"},{"name":"stromal sarcoma, malignant","type":"exact"},{"name":"stromal tumor, malignant","type":"exact"}],"termid":"MONDO:0044337","xrefs":{"Monarch":{"xref_id":"0044337"}}}


id: PR:P40236
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- hhp2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P40236"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"casein kinase I homolog hhp2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC23C4.12","synonyms":[{"name":"Spom972h-hhp2","type":"exact"}],"termid":"PR:P40236"}


id: PBO:0086136
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for membrane insertion of C-terminus of Cox2p; mitochondrial integral inner membrane protein; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC; respiratory defect of the null mutant is functionally complemented by human COX18 carrying the N-terminal 54 amino acids of S. cerevisiae Cox18p","termid":"PBO:0086136"}


id: PBO:0089118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic spindle pole body KASH domain protein Kms1","termid":"PBO:0089118"}


id: GO:0061524
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.","definition_xrefs":["PMID:23409159","GOC:dph","GOC:cvs"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"spinal cord development","termid":"GO:0021510"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"central canal development","termid":"GO:0061524"}


id: PBO:0087673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p; stimulates the GTPase activity of Rag family GTPase Gtr2p, within the context of the Gtr1p-Gtr2p heterodimer, after amino acid stimulation; required for activation of TORC1 in response to amino acid stimulation; recruited to the vacuolar membrane during amino acid starvation and released from the membrane by TORC1; required for the transport of amino acid permease Gap1p from the Golgi to the cell surface","termid":"PBO:0087673"}


id: PBO:0050673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 8","termid":"PBO:0050673"}


id: GO:0097333
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.","definition_xrefs":["GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to olanzapine","termid":"GO:0097333"}


id: SO:0000062
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An intrachromosomal transposition whereby a translocation in which one of the four broken ends loses a segment before re-joining.","definition_xrefs":["FB:reference_manual"],"direct_ancestors":[{"relation_name":"has_part","term_name":"deletion","termid":"SO:0000159"},{"relation_name":"is_a","term_name":"chromosomal_deletion","termid":"SO:1000029"},{"relation_name":"is_a","term_name":"intrachromosomal_transposition","termid":"SO:1000041"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deficient_intrachromosomal_transposition","synonyms":[{"name":"deficient intrachromosomal transposition","type":"exact"}],"termid":"SO:0000062"}


id: GO:0140028
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes.","definition_xrefs":["PMID:22323285","Wikipedia:Exocytosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"exocytic process","termid":"GO:0140029"},{"relation_name":"part_of","term_name":"contractile vacuole discharge","termid":"GO:0070177"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"part_of","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0016192","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"pore formation during contractile vacuole discharge","termid":"GO:0140028"}


id: PBO:0088613
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear HMG-like acidic protein Mak16","termid":"PBO:0088613"}


id: PATO:0002069
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A spatial pattern inhering in a bearer by virtue of the bearer's lacking a layered configuration.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stratification","termid":"PATO:0002067"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unstratified","termid":"PATO:0002069"}


id: FYPO:0005168
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein level during vegetative growth","termid":"FYPO:0000833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000257","FYPO:0001312","FYPO:0000002"],"is_obsolete":false,"name":"normal protein level during cellular response to salt stress","synonyms":[{"name":"normal protein accumulation during cellular response to salt stress","type":"related"},{"name":"normal protein level during cellular response to salt stress during mitotic cell cycle","type":"related"},{"name":"normal protein level during cellular response to salt stress during vegetative growth","type":"exact"}],"termid":"FYPO:0005168"}


id: GO:0036133
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.","definition_xrefs":["KEGG_REACTION:R05060","GOC:mw","PMID:3461463","PMID:3823488","PMID:8200461"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"11-hydroxythromboxane B2 dehydrogenase activity","secondary_identifiers":["Reactome:R-HSA-2161732","RHEA:52312"],"synonyms":[{"name":"NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity","type":"exact"}],"termid":"GO:0036133"}


id: MONDO:0010131
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, autosomal recessive inherited disorder usually caused by mutations in the THRB gene. It is characterized by a defective physiological resistance to thyroid hormones, resulting in the elevation of thyroxin and triiodothyronine in the serum.","definition_xrefs":["NCIT:C85191"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete syndromic genetic hearing loss (obsolete MONDO:0019589)","termid":"MONDO:0019589"},{"relation_name":"is_a","term_name":"generalized resistance to thyroid hormone","termid":"MONDO:0009043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"thyroid hormone resistance, generalized, autosomal recessive","secondary_identifiers":["HGNC:11799","MEDGEN:483749","NANDO:2200341","MESH:C567936","NANDO:1200395","UMLS:C3489796","NANDO:2100121","OMIM:274300"],"synonyms":[{"name":"GRTH","type":"related"},{"name":"Gthr","type":"related"},{"name":"Refetoff syndrome","type":"related"},{"name":"THRB","type":"related"},{"name":"thyroid hormone receptor BETA","type":"related"},{"name":"thyroid hormone resistance","type":"broad"},{"name":"thyroid hormone resistance syndrome","type":"broad"},{"name":"thyroid hormone resistance, autosomal recessive","type":"exact"},{"name":"thyroid hormone resistance, generalized, autosomal recessive","type":"exact"},{"name":"thyroid hormone unresponsiveness","type":"related"}],"termid":"MONDO:0010131","xrefs":{"Monarch":{"xref_id":"0010131"}}}


id: GO:0033812
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.","definition_xrefs":["RHEA:19481"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetyl-CoA C-acyltransferase activity","termid":"GO:0003988"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016740","GO:0016746"],"is_obsolete":false,"name":"3-oxoadipyl-CoA thiolase activity","secondary_identifiers":["MetaCyc:RXN-3641","EC:2.3.1.174"],"synonyms":[{"name":"succinyl-CoA:acetyl-CoA C-succinyltransferase activity","type":"related"}],"termid":"GO:0033812"}


id: GO:1905158
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of Factor XII activation.","definition_xrefs":["GOC:TermGenie","PMID:617517","GO_REF:0000058"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of Factor XII activation (obsolete GO:1905158)","synonyms":[{"name":"regulation of Hageman factor activation","type":"exact"}],"termid":"GO:1905158"}


id: MONDO:0015485
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete primary hereditary glaucoma (obsolete MONDO:0015485)","secondary_identifiers":["Orphanet:156005"],"synonyms":[{"name":"primary glaucoma","type":"related"}],"termid":"MONDO:0015485","xrefs":{"Monarch":{"xref_id":"0015485"}}}


id: GO:0140567
data:
  {"annotated_genes":["SJAG_01435","SJAG_04203"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[100821,116100],"is_not":false,"summary":null,"term":"GO:0140567"}]},"cv_name":"molecular_function","definition":"The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. The reaction is driven by ATP hydrolysis.","definition_xrefs":["PMID:24821790","PMID:28712723","PMID:32973005"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein transporter activity","termid":"GO:0140318"},{"relation_name":"is_a","term_name":"ATP-dependent activity","termid":"GO:0140657"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01435":null,"SJAG_04203":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0140318"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0140318"],"is_obsolete":false,"name":"membrane protein dislocase activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"transmembrane helix dislocasentransmembrane protein dislocase activity","type":"related"}],"termid":"GO:0140567","terms_by_termid":{"GO:0140567":null}}


id: PBO:0074055
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC25A34 and TMEM82 antisense RNA 1","termid":"PBO:0074055"}


id: GO:0030879
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.","definition_xrefs":["PMID:9576833"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gland development","termid":"GO:0048732"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mammary gland development","synonyms":[{"name":"mammogenesis","type":"narrow"}],"termid":"GO:0030879"}


id: PBO:0067578
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 735, pseudogene","termid":"PBO:0067578"}


id: PBO:0113084
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic ankyrin repeat-containing protein; co-purifies with Myo3p and Myo5p by large-scale affinity capture; localization of the long-tailed type I myosins is altered in the null mutant; N-terminally propionylated in vivo; contains three ankyrin repeats and an acidic tail; orthologous to human OSTF1","termid":"PBO:0113084"}


id: GO:0001934
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein phosphorylation","termid":"GO:0001932"},{"relation_name":"is_a","term_name":"positive regulation of protein modification process","termid":"GO:0031401"},{"relation_name":"is_a","term_name":"positive regulation of phosphorylation","termid":"GO:0042327"},{"relation_name":"positively_regulates","term_name":"protein phosphorylation","termid":"GO:0006468"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein phosphorylation","synonyms":[{"name":"activation of protein amino acid phosphorylation","type":"narrow"},{"name":"positive regulation of protein amino acid phosphorylation","type":"exact"},{"name":"stimulation of protein amino acid phosphorylation","type":"narrow"},{"name":"up regulation of protein amino acid phosphorylation","type":"exact"},{"name":"up-regulation of protein amino acid phosphorylation","type":"exact"},{"name":"upregulation of protein amino acid phosphorylation","type":"exact"}],"termid":"GO:0001934"}


id: PBO:0067409
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 519, pseudogene","termid":"PBO:0067409"}


id: PBO:0039054
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"angiogenic factor with G-patch and FHA domains 1 pseudogene 3","termid":"PBO:0039054"}


id: PBO:0034298
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-proper_distributary_of","termid":"PBO:0034298"}


id: GO:0060963
data:
  {"annotated_genes":["SJAG_02671","SJAG_02723","SJAG_01243","SJAG_03241"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[87749,89251,93294,106458],"is_not":false,"summary":null,"term":"GO:0060963"}]},"cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.","definition_xrefs":["GOC:txnOH","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transcription by RNA polymerase II","termid":"GO:0045944"},{"relation_name":"is_a","term_name":"regulation of ribosomal protein gene transcription by RNA polymerase II","termid":"GO:0060962"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01243":null,"SJAG_02671":null,"SJAG_02723":null,"SJAG_03241":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"positively_regulates","termid":"GO:0006351"},{"rel_name":"regulates","termid":"GO:0006351"}],"interesting_parent_ids":["GO:0006355","GO:0006351","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"positive regulation of ribosomal protein gene transcription by RNA polymerase II","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:0060963","terms_by_termid":{"GO:0060963":null}}


id: FYPO:0003673
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of ATP binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal molecular function","termid":"FYPO:0000706"},{"relation_name":"is_a","term_name":"binding phenotype","termid":"FYPO:0001092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000652"],"is_obsolete":false,"name":"normal ATP binding","termid":"FYPO:0003673"}


id: PBO:0050697
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 12A","termid":"PBO:0050697"}


id: GO:0048247
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a lymphocyte in response to an external stimulus.","definition_xrefs":["GOC:hjd","GOC:jid","PMID:12391252"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte chemotaxis","termid":"GO:0030595"},{"relation_name":"is_a","term_name":"lymphocyte migration","termid":"GO:0072676"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lymphocyte chemotaxis","termid":"GO:0048247"}


id: PBO:0067341
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 435, pseudogene","termid":"PBO:0067341"}


id: PBO:0018233
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation initiation factor eIF2 assembly protein","termid":"PBO:0018233"}


id: PBO:0076816
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"teneurin transmembrane protein 3","termid":"PBO:0076816"}


id: GO:0047082
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H+ + NADPH + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.","definition_xrefs":["EC:1.14.14.93","RHEA:15321"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"3,9-dihydroxypterocarpan 6a-monooxygenase activity","secondary_identifiers":["MetaCyc:RXN-4505","KEGG_REACTION:R03452"],"synonyms":[{"name":"(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating)","type":"related"},{"name":"3,9-dihydroxypterocarpan 6a-hydroxylase activity","type":"exact"},{"name":"3,9-dihydroxypterocarpan 6alpha-monooxygenase","type":"related"}],"termid":"GO:0047082"}


id: PBO:0043561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type V alpha 3 chain","termid":"PBO:0043561"}


id: PATO:0001255
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A color consisting of orange hue and high brightness.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"orange","termid":"PATO:0000953"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"light orange","termid":"PATO:0001255"}


id: GO:0120524
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a long-chain 2,3-saturated fatty acyl-CoA + O2 = a long-chain (2E)-enoyl-CoA + H2O2.","definition_xrefs":["RHEA:78851"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA oxidase activity","termid":"GO:0003997"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"long-chain fatty acyl-CoA oxidase activity","termid":"GO:0120524"}


id: PATO:0002081
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A broken quality inhering in a bearer by virtue of the bearer's being broken into multiple contiguous wholes.","definition_xrefs":["PATOC:GJM"],"direct_ancestors":[{"relation_name":"is_a","term_name":"broken","termid":"PATO:0001444"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"shattered","termid":"PATO:0002081"}


id: SO:0000389
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A 109-nucleotide RNA of E. coli that seems to have a regulatory role on the galactose operon. Changes in Spot 42 levels are implicated in affecting DNA polymerase I levels.","direct_ancestors":[{"relation_name":"is_a","term_name":"small_regulatory_ncRNA","termid":"SO:0000370"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spot_42_RNA","secondary_identifiers":["http://en.wikipedia.org/wiki/Spot_42_RNA"],"synonyms":[{"name":"spot-42 RNA","type":"exact"}],"termid":"SO:0000389"}


id: MONDO:1010479
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Arrhythmogenic right ventricular cardiomyopathy that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arrhythmogenic right ventricular cardiomyopathy, non-human animal","termid":"MONDO:1010019"},{"relation_name":"is_a","term_name":"cardiomyopathy, domestic cat","termid":"MONDO:1010442"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arrhythmogenic right ventricular cardiomyopathy, domestic cat","secondary_identifiers":["OMIA:000878-9685"],"termid":"MONDO:1010479","xrefs":{"Monarch":{"xref_id":"1010479"}}}


id: PBO:0064998
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PR/SET domain 5","termid":"PBO:0064998"}


id: PBO:0031560
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_catalytic_activity","termid":"PBO:0031560"}


id: PBO:0068999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 243, pseudogene","termid":"PBO:0068999"}


id: GO:0043810
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids.","definition_xrefs":["PMID:15341653","RHEA:20633"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acyltransferase activity","termid":"GO:0016410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0016746","GO:0003824"],"is_obsolete":false,"name":"ornithine-acyl [acyl carrier protein] N-acyltransferase activity","secondary_identifiers":["EC:2.3.2.30"],"synonyms":[{"name":"L-ornithine N(alpha)-acyltransferase","type":"exact"},{"name":"ornithine-acyl[acyl carrier protein] N-acyltransferase activity","type":"exact"}],"termid":"GO:0043810"}


id: PBO:0044724
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEAD/H-box helicase 11 like 11 (pseudogene)","termid":"PBO:0044724"}


id: GO:1903779
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cardiac conduction.","definition_xrefs":["GOC:mtg_cardiac_conduct_nov11","GOC:rph","PMID:12967627","GOC:BHF","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of heart contraction","termid":"GO:0008016"},{"relation_name":"regulates","term_name":"cardiac conduction","termid":"GO:0061337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cardiac conduction","secondary_identifiers":["Reactome:R-HSA-5578768","Reactome:R-HSA-5578775"],"termid":"GO:1903779"}


id: GO:0033694
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors","termid":"GO:0016645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor","secondary_identifiers":["EC:1.5.7.-"],"termid":"GO:0033694"}


id: GO:0018553
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity (obsolete GO:0018553)","termid":"GO:0018553"}


id: PBO:0054828
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2241","termid":"PBO:0054828"}


id: PBO:0005224
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"separase/separin","termid":"PBO:0005224"}


id: PBO:0043394
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-X9-C motif containing 1","termid":"PBO:0043394"}


id: PBO:0036458
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Smaug family RNA binding protein involved in CCR4-NOT dependent deadenylation (predicted)","termid":"PBO:0036458"}


id: GO:0022614
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.","definition_xrefs":["GOC:isa_complete"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane docking","termid":"GO:0022406"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"membrane to membrane docking","synonyms":[{"name":"membrane-membrane docking","type":"exact"}],"termid":"GO:0022614"}


id: PBO:0087520
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity; null mutation is functionally complemented by human ELP4","termid":"PBO:0087520"}


id: RO:0002002
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity","direct_ancestors":[{"relation_name":"is_a","term_name":"mereotopologically_related_to","termid":"RO:0002323"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_2D_boundary","termid":"RO:0002002"}


id: GO:0098789
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.","gene_count":0,"genotype_count":0,"name":"obsolete pre-mRNA cleavage required for polyadenylation (obsolete GO:0098789)","synonyms":[{"name":"cleavage and polyadenylylation specificity factor activity","type":"related"},{"name":"pre-mRNA cleavage factor activity","type":"exact"}],"termid":"GO:0098789"}


id: PBO:0002402
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.1.1.145","termid":"PBO:0002402"}


id: GO:0090333
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of stomatal movement","termid":"GO:0010119"},{"relation_name":"regulates","term_name":"stomatal closure","termid":"GO:0090332"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of stomatal closure","termid":"GO:0090333"}


id: PBO:0030628
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cell_population_growth_on_trehalose_carbon_source","termid":"PBO:0030628"}


id: MONDO:0018676
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune disease of ear, nose and throat","termid":"MONDO:0000587"},{"relation_name":"is_a","term_name":"IgG4-related disease","termid":"MONDO:0017287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"eosinophilic angiocentric fibrosis","secondary_identifiers":["UMLS:C5578050","MEDGEN:1814179","Orphanet:449566","GARD:21886","icd11.foundation:57609544"],"synonyms":[{"name":"EAF","type":"related"},{"name":"IgG4-related eosinophilic angiocentric fibrosis","type":"exact"},{"name":"Sinonasal eosinophilic angiocentric fibrosis","type":"related"},{"name":"eosinophilic angiocentric fibrosis","type":"exact"}],"termid":"MONDO:0018676","xrefs":{"Monarch":{"xref_id":"0018676"}}}


id: GO:0005223
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.","definition_xrefs":["GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellularly cyclic nucleotide-activated monoatomic cation channel activity","termid":"GO:0005221"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"intracellularly cGMP-activated cation channel activity","synonyms":[{"name":"intracellular cGMP activated cation channel activity","type":"exact"},{"name":"intracellular cGMP-activated cation channel activity","type":"exact"}],"termid":"GO:0005223"}


id: PBO:0068302
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein 7","termid":"PBO:0068302"}


id: GO:0097513
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A bipolar filament composed of myosin II molecules.","definition_xrefs":["GOC:cjm","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myosin filament","termid":"GO:0032982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"myosin II filament","termid":"GO:0097513"}


id: PBO:0066856
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 156","termid":"PBO:0066856"}


id: GO:1990863
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).","definition_xrefs":["PMID:9788538"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell proliferation","termid":"GO:0050673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"acinar cell proliferation","synonyms":[{"name":"acinic cell proliferation","type":"exact"},{"name":"acinous cell proliferation","type":"exact"}],"termid":"GO:1990863"}


id: GO:0046101
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine nucleobase biosynthetic process","termid":"GO:0009113"},{"relation_name":"is_a","term_name":"hypoxanthine metabolic process","termid":"GO:0046100"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"hypoxanthine biosynthetic process","synonyms":[{"name":"hypoxanthine anabolism","type":"exact"},{"name":"hypoxanthine biosynthesis","type":"exact"},{"name":"hypoxanthine formation","type":"exact"},{"name":"hypoxanthine synthesis","type":"exact"}],"termid":"GO:0046101"}


id: GO:0046887
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell communication","termid":"GO:0010647"},{"relation_name":"is_a","term_name":"positive regulation of signaling","termid":"GO:0023056"},{"relation_name":"is_a","term_name":"regulation of hormone secretion","termid":"GO:0046883"},{"relation_name":"is_a","term_name":"positive regulation of secretion by cell","termid":"GO:1903532"},{"relation_name":"positively_regulates","term_name":"hormone secretion","termid":"GO:0046879"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0023052","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of hormone secretion","synonyms":[{"name":"activation of hormone secretion","type":"narrow"},{"name":"stimulation of hormone secretion","type":"narrow"},{"name":"up regulation of hormone secretion","type":"exact"},{"name":"up-regulation of hormone secretion","type":"exact"},{"name":"upregulation of hormone secretion","type":"exact"}],"termid":"GO:0046887"}


id: PBO:0060786
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B11 pseudogene 1","termid":"PBO:0060786"}


id: MONDO:0019680
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Genochondromatosis type 2 is a rare genetic bone development disorder characterized by normal clavicles and symmetrical generalized metaphyseal enchondromas particularly in the distal femur, proximal humerus, and bones of the wrists, hands, and feet. Lesions regress later in life with growth cartilage obliteration. Clinical examination is normal and the course of the disease is benign.","definition_xrefs":["Orphanet:93398"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with disorganized development of skeletal components (obsolete MONDO:0019708)","termid":"MONDO:0019708"},{"relation_name":"is_a","term_name":"genochondromatosis","termid":"MONDO:0007653"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"genochondromatosis type 2","secondary_identifiers":["UMLS:C4511481","MEDGEN:1374044","GARD:16820","icd11.foundation:1033432522","SCTID:725904009"],"termid":"MONDO:0019680","xrefs":{"Monarch":{"xref_id":"0019680"}}}


id: PBO:0080333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 97 pseudogene","termid":"PBO:0080333"}


id: PBO:0063458
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"platelet derived growth factor subunit A","termid":"PBO:0063458"}


id: PBO:0063449
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphodiesterase 8A","termid":"PBO:0063449"}


id: MONDO:0024548
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any peeling skin syndrome in which the cause of the disease is a mutation in the CDSN gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"generalized peeling skin syndrome","termid":"MONDO:0010033"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"peeling skin syndrome 1","secondary_identifiers":["UMLS:C1849193","DOID:0070520","GARD:17259","MEDGEN:336530","OMIM:270300","Orphanet:263553"],"synonyms":[{"name":"CDSN peeling skin syndrome","type":"exact"},{"name":"PSS","type":"related"},{"name":"PSS type B","type":"exact"},{"name":"PSS1","type":"related"},{"name":"deciduous skin","type":"related"},{"name":"generalised deciduous skin type B","type":"exact"},{"name":"generalised peeling skin syndrome type B","type":"exact"},{"name":"generalized deciduous skin type B","type":"exact"},{"name":"generalized peeling skin syndrome type B","type":"exact"},{"name":"inflammatory peeling skin syndrome","type":"exact"},{"name":"keratolysis exfoliativa congenita","type":"related"},{"name":"peeling skin syndrome 1","type":"exact"},{"name":"peeling skin syndrome caused by mutation in CDSN","type":"exact"},{"name":"peeling skin syndrome type B","type":"exact"},{"name":"skin peeling, familial continuous generalised","type":"related"},{"name":"skin peeling, familial continuous generalized","type":"related"}],"termid":"MONDO:0024548","xrefs":{"Monarch":{"xref_id":"0024548"}}}


