# terms

id: PR:Q9P7W6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA mismatch repair protein Mlh1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03475"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MutL protein homolog 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1703.04","secondary_identifiers":["UniProtKB:Q9P7W6"],"synonyms":[{"name":"DNA mismatch repair protein MLH1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-MLH1","type":"exact"}],"termid":"PR:Q9P7W6"}


id: PBO:0061287
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore associated protein 1 pseudogene 8","termid":"PBO:0061287"}


id: PBO:0018218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heme import protein Shu1","termid":"PBO:0018218"}


id: FYPO:0006741
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at promoters containing one or more MluI cell cycle box factor elements (MCBs). Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes.","definition_xrefs":["PomBase:mah","PMID:30134042"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nucleosome positioning in euchromatin","termid":"FYPO:0000854"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000641"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0000641"],"is_obsolete":false,"name":"increased nucleosome occupancy at MCB promoters","synonyms":[{"name":"increased nucleosome occupancy at MCB promoter during mitotic cell cycle","type":"related"},{"name":"increased nucleosome occupancy at MCB promoter during vegetative growth","type":"exact"},{"name":"increased nucleosome occupancy at MCB promoters target genes","type":"related"}],"termid":"FYPO:0006741"}


id: GO:0008978
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.","definition_xrefs":["EC:3.4.23.43"],"gene_count":0,"genotype_count":0,"name":"obsolete prepilin peptidase activity (obsolete GO:0008978)","synonyms":[{"name":"prepilin peptidase activity","type":"exact"}],"termid":"GO:0008978"}


id: PBO:0084927
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA 5'-end-capping quality-control protein; has distributive, 5'-3' exoRNase activity; involved in the decapping of nicotinamide adenine dinucleotide (NAD) capped nuclear NAD-RNAs; similar to Rai1p","termid":"PBO:0084927"}


id: GO:1900722
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein adenylylation.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein modification process","termid":"GO:0031399"},{"relation_name":"regulates","term_name":"protein adenylylation","termid":"GO:0018117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of protein adenylylation","synonyms":[{"name":"regulation of protein AMPylation","type":"exact"},{"name":"regulation of protein adenylation","type":"exact"},{"name":"regulation of protein amino acid adenylylation","type":"exact"}],"termid":"GO:1900722"}


id: PBO:0091308
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human RAB6A","termid":"PBO:0091308"}


id: MONDO:0000325
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pachyonychia congenita (obsolete MONDO:0000325)","termid":"MONDO:0000325","xrefs":{"Monarch":{"xref_id":"0000325"}}}


id: PBO:0066944
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 246","termid":"PBO:0066944"}


id: FYPO:0004415
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a phosphatase activity is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased catalytic activity","termid":"FYPO:0000662"},{"relation_name":"is_a","term_name":"abnormal phosphatase activity","termid":"FYPO:0004302"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0000661","FYPO:0000652","FYPO:0000654","FYPO:0001985"],"is_obsolete":false,"name":"increased phosphatase activity","termid":"FYPO:0004415"}


id: GO:0051804
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.","definition_xrefs":["GOC:add"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of cytolysis in other organism involved in symbiotic interaction (obsolete GO:0051804)","synonyms":[{"name":"activation of cytolysis of cells in other organism during symbiotic interaction","type":"narrow"},{"name":"positive regulation of cytolysis of cells in other organism during symbiotic interaction","type":"related"},{"name":"positive regulation of cytolysis of cells in other organism involved in symbiotic interaction","type":"exact"},{"name":"stimulation of cytolysis of cells in other organism during symbiotic interaction","type":"narrow"},{"name":"up regulation of cytolysis of cells in other organism during symbiotic interaction","type":"exact"},{"name":"up-regulation of cytolysis of cells in other organism during symbiotic interaction","type":"exact"},{"name":"upregulation of cytolysis of cells in other organism during symbiotic interaction","type":"exact"}],"termid":"GO:0051804"}


id: PBO:0002140
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae SUB2","termid":"PBO:0002140"}


id: GO:0003037
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.","definition_xrefs":["GOC:mtg_cardio"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of pH by chemoreceptor signaling","termid":"GO:0003022"},{"relation_name":"part_of","term_name":"detection of hypoxic conditions in blood by carotid body chemoreceptor signaling","termid":"GO:0003029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of pH by carotid body chemoreceptor signaling","synonyms":[{"name":"detection of pH by carotid body chemoreceptor signalling","type":"exact"}],"termid":"GO:0003037"}


id: GO:0102348
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: behenoyl-CoA + NADP = trans-2-docosenoyl-CoA + NADPH + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete trans-docosan-2-enoyl-CoA reductase activity (obsolete GO:0102348)","termid":"GO:0102348"}


id: PBO:0039780
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aquaporin 7 pseudogene 5","termid":"PBO:0039780"}


id: MONDO:0018513
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A squamous cell carcinoma that involves the colon.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colon carcinoma","termid":"MONDO:0002032"},{"relation_name":"is_a","term_name":"colorectal squamous cell carcinoma","termid":"MONDO:0006165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"squamous cell carcinoma of colon","secondary_identifiers":["UMLS:C1333100","DOID:5519","MEDGEN:272494","NCIT:C5490","Orphanet:423994","SCTID:766981007","GARD:21768"],"synonyms":[{"name":"colon epidermoid carcinoma","type":"exact"},{"name":"colon squamous cell cancer","type":"exact"},{"name":"colon squamous cell carcinoma","type":"exact"},{"name":"colonic epidermoid carcinoma","type":"exact"},{"name":"colonic squamous cell carcinoma","type":"exact"},{"name":"epidermoid carcinoma of colon","type":"exact"},{"name":"epidermoid carcinoma of the colon","type":"exact"},{"name":"squamous cell carcinoma of colon","type":"exact"},{"name":"squamous cell carcinoma of the colon","type":"exact"},{"name":"squamous cell colon carcinoma","type":"exact"}],"termid":"MONDO:0018513","xrefs":{"Monarch":{"xref_id":"0018513"}}}


id: GO:0045724
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the formation of a cilium.","definition_xrefs":["GOC:go_curators","GOC:cilia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of plasma membrane bounded cell projection assembly","termid":"GO:0120034"},{"relation_name":"is_a","term_name":"regulation of cilium assembly","termid":"GO:1902017"},{"relation_name":"is_a","term_name":"positive regulation of organelle assembly","termid":"GO:1902117"},{"relation_name":"positively_regulates","term_name":"cilium assembly","termid":"GO:0060271"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"positively_regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"positive regulation of cilium assembly","synonyms":[{"name":"activation of cilium assembly","type":"narrow"},{"name":"positive regulation of flagellum assembly","type":"broad"},{"name":"positive regulation of flagellum biogenesis","type":"related"},{"name":"stimulation of cilium assembly","type":"narrow"},{"name":"up regulation of cilium assembly","type":"exact"},{"name":"up-regulation of cilium assembly","type":"exact"},{"name":"upregulation of cilium assembly","type":"exact"}],"termid":"GO:0045724"}


id: PBO:0070347
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY4 pseudogene 20","termid":"PBO:0070347"}


id: GO:0110081
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.","definition_xrefs":["GOC:BHF_miRNA","GOC:rph","GOC:BHF","PMID:27748453"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"regulation of placenta blood vessel development","termid":"GO:0110079"},{"relation_name":"negatively_regulates","term_name":"placenta blood vessel development","termid":"GO:0060674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of placenta blood vessel development","termid":"GO:0110081"}


id: MONDO:1010078
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Polycythemia that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune system disorder, non-human animal","termid":"MONDO:0700106"},{"relation_name":"is_a","term_name":"hematologic disorder, non-human animal","termid":"MONDO:1011319"},{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polycythemia, non-human animal","secondary_identifiers":["OMIA:000809"],"termid":"MONDO:1010078","xrefs":{"Monarch":{"xref_id":"1010078"}}}


id: GO:0030624
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a U6atac small nuclear RNA (U6atac snRNA).","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"snRNA binding","termid":"GO:0017069"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003723"}],"interesting_parent_ids":["GO:0005488","GO:0003723","GO:0003674"],"is_obsolete":false,"name":"U6atac snRNA binding","termid":"GO:0030624"}


id: PBO:0059537
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded transcription factor binding site L","termid":"PBO:0059537"}


id: GO:0031554
data:
  {"annotated_genes":["SJAG_03126"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[111710],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904595"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.","definition_xrefs":["GOC:txnOH","GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein-containing complex disassembly","termid":"GO:0043244"},{"relation_name":"is_a","term_name":"regulation of RNA biosynthetic process","termid":"GO:2001141"},{"relation_name":"regulates","term_name":"DNA-templated transcription termination","termid":"GO:0006353"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03126":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of termination of DNA-templated transcription","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of DNA-dependent transcription, termination","type":"exact"},{"name":"regulation of DNA-templated transcription, termination","type":"exact"},{"name":"regulation of transcription termination, DNA-dependent","type":"exact"},{"name":"transcription antiterminator activity","type":"related"}],"termid":"GO:0031554","terms_by_termid":{"GO:1904595":null}}


id: PBO:0036496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KH domain RNA-binding protein Rnc1","termid":"PBO:0036496"}


id: MONDO:0958186
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hematuria, benign familial","termid":"MONDO:0957317"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hematuria, benign familial, 2","secondary_identifiers":["UMLS:C5830421","OMIM:620320","MEDGEN:1841057"],"termid":"MONDO:0958186","xrefs":{"Monarch":{"xref_id":"0958186"}}}


id: PBO:0042232
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin Y like 4 (pseudogene)","termid":"PBO:0042232"}


id: PBO:0036024
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histone_H3-K9_acetylation_during_vegetative_growth","termid":"PBO:0036024"}


id: MONDO:0000730
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pontocerebellar hypoplasia (obsolete MONDO:0000730)","termid":"MONDO:0000730","xrefs":{"Monarch":{"xref_id":"0000730"}}}


id: GO:0046002
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle.","definition_xrefs":["GOC:dph","GOC:go_curators","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of preblastoderm mitotic cell cycle","termid":"GO:0007347"},{"relation_name":"is_a","term_name":"positive regulation of mitotic cell cycle, embryonic","termid":"GO:0045977"},{"relation_name":"positively_regulates","term_name":"preblastoderm mitotic cell cycle","termid":"GO:0035185"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"positive regulation of preblastoderm mitotic cell cycle","synonyms":[{"name":"activation of progression through preblastoderm mitotic cell cycle","type":"narrow"},{"name":"positive regulation of preblastoderm mitotic cell cycle progression","type":"exact"},{"name":"positive regulation of progression through preblastoderm mitotic cell cycle","type":"exact"},{"name":"stimulation of progression through preblastoderm mitotic cell cycle","type":"narrow"},{"name":"up regulation of progression through preblastoderm mitotic cell cycle","type":"exact"},{"name":"up-regulation of progression through preblastoderm mitotic cell cycle","type":"exact"},{"name":"upregulation of progression through preblastoderm mitotic cell cycle","type":"exact"}],"termid":"GO:0046002"}


id: MONDO:0957464
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cutaneous tuberculosis","termid":"MONDO:0021948"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"primary cutaneous tuberculosis","secondary_identifiers":["Orphanet:645849","MEDGEN:1843421","UMLS:C5816706"],"termid":"MONDO:0957464","xrefs":{"Monarch":{"xref_id":"0957464"}}}


id: PBO:0064201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PLAC8 like 1","termid":"PBO:0064201"}


id: PBO:0058234
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4523","termid":"PBO:0058234"}


id: GO:0047104
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: CoA + NAD+ + palmitaldehyde = H+ + NADH + palmitoyl-CoA.","definition_xrefs":["RHEA:19705","EC:1.2.1.42"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","termid":"GO:0016620"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"hexadecanal dehydrogenase (acylating) activity","secondary_identifiers":["KEGG_REACTION:R01277","UM-BBD_reactionID:r1374","MetaCyc:1.2.1.42-RXN"],"synonyms":[{"name":"fatty acyl-CoA reductase activity","type":"broad"},{"name":"hexadecanal:NAD+ oxidoreductase (CoA-acylating)","type":"related"}],"termid":"GO:0047104"}


id: MONDO:0007399
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any craniosynostosis in which the cause of the disease is a mutation in the TWIST1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene","PMID:17343269"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isolated oxycephaly","termid":"MONDO:0018971"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"TWIST1-related craniosynostosis","secondary_identifiers":["GARD:18045","OMIM:123100","SCTID:57219006","MEDGEN:1646646","UMLS:C4551902","NORD:1606"],"synonyms":[{"name":"CRS","type":"related"},{"name":"CRS1","type":"related"},{"name":"Primary Craniosynostosis","type":"exact"},{"name":"TWIST1-related craniosynostosis","type":"exact"},{"name":"craniostenosis","type":"related"},{"name":"craniosynostosis 1","type":"exact"},{"name":"craniosynostosis type 1","type":"exact"}],"termid":"MONDO:0007399","xrefs":{"Monarch":{"xref_id":"0007399"}}}


id: PBO:0039360
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"APC membrane recruitment protein 2","termid":"PBO:0039360"}


id: PBO:0032713
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_error-prone_translesion_synthesis","termid":"PBO:0032713"}


id: GO:1990333
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.","definition_xrefs":["PMID:15879521","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"},{"relation_name":"part_of","term_name":"mitotic checkpoint complex","termid":"GO:0033597"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"mitotic checkpoint complex, CDC20-MAD2 subcomplex","synonyms":[{"name":"CDC20-MAD2 complex","type":"exact"}],"termid":"GO:1990333"}


id: PBO:0110192
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NaTtoU","termid":"PBO:0110192"}


id: MONDO:0020277
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete ectodermal malformation syndrome associated with ocular features (obsolete MONDO:0020277)","termid":"MONDO:0020277","xrefs":{"Monarch":{"xref_id":"0020277"}}}


id: MONDO:0008645
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"This syndrome is characterized by cardiac arrhythmias (ventricular extrasystoles manifesting as bigeminy or multifocal tachycardia with syncopal episodes), perodactyly (hypoplasia and/or agenesis of the distal phalanges of the toes) and Pierre-Robin sequence.","definition_xrefs":["Orphanet:3201"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ventricular extrasystoles with syncopal episodes-perodactyly-robin sequence syndrome","secondary_identifiers":["GARD:5472","MESH:C537497","MEDGEN:395493","OMIM:192445","SCTID:719823007","UMLS:C1860471"],"synonyms":[{"name":"Stoll-Kieny-Dott syndrome","type":"exact"},{"name":"ventricular extrasystoles perodactyly Robin sequence","type":"related"},{"name":"ventricular extrasystoles with syncopal episodes - perodactyly - Robin sequence","type":"related"},{"name":"ventricular extrasystoles with syncope, perodactyly, and ROBIN sequence","type":"related"}],"termid":"MONDO:0008645","xrefs":{"Monarch":{"xref_id":"0008645"}}}


id: PBO:0043232
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chloride voltage-gated channel 3 pseudogene 1","termid":"PBO:0043232"}


id: PBO:0091134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit L53","termid":"PBO:0091134"}


id: PR:Q09874
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC12G12.11c gene.","definition_xrefs":["UniProtKB:Q09874","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C12G12.11c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC12G12.11c","synonyms":[{"name":"Spom972h-SPAC12G12.11c","type":"exact"}],"termid":"PR:Q09874"}


id: MONDO:0020771
data:
  {"annotated_genes":["SJAG_03923","SJAG_02242","SJAG_04418"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85375],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011801"},{"annotations":[86386,86387],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0018996"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive cerebellar ataxia","termid":"MONDO:0015244"},{"relation_name":"is_a","term_name":"DNA repair disease","termid":"MONDO:0021190"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02242":null,"SJAG_03923":null,"SJAG_04418":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021190"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0006025","MONDO:0021190","MONDO:0005559"],"is_obsolete":false,"name":"spinocerebellar ataxia, autosomal recessive, with axonal neuropathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:337609","OMIMPS:607250","UMLS:C1846574"],"synonyms":[{"name":"SCAN","type":"exact"}],"termid":"MONDO:0020771","terms_by_termid":{"MONDO:0011801":null,"MONDO:0018996":null},"xrefs":{"Monarch":{"xref_id":"0020771"}}}


id: GO:0140956
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysyl79-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl79-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of up to three methyl group to the lysine residue at position 79 of the histone H3 protein, producing H3K79me3.","definition_xrefs":["PMID:15371351","RHEA:60328"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H3K79 methyltransferase activity","termid":"GO:0031151"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0008276","GO:0016740","GO:0003674","GO:0003824","GO:0140096","GO:0016741"],"is_obsolete":false,"name":"histone H3K79 trimethyltransferase activity","secondary_identifiers":["EC:2.1.1.360"],"synonyms":[{"name":"histone H3-K79 trimethylation","type":"broad"},{"name":"histone H3K79 trimethylase activity","type":"exact"},{"name":"histone H3K79 trimethylation","type":"broad"},{"name":"histone lysine N-trimethyltransferase activity (H3-K79 specific)","type":"exact"},{"name":"histone trimethylase activity (H3-K79 specific)","type":"exact"},{"name":"histone trimethyltransferase activity (H3-K79 specific)","type":"exact"},{"name":"histone-H3K79 trimethyltransferase activity","type":"exact"}],"termid":"GO:0140956"}


id: MONDO:0005909
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with viruses of the genus pestivirus, family flaviviridae.","definition_xrefs":["MESH:D018182"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Flaviviridae infectious disease","termid":"MONDO:0005763"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pestivirus infectious disease","secondary_identifiers":["EFO:0007432","MEDGEN:60191","UMLS:C0206611"],"synonyms":[{"name":"Pestivirus caused disease or disorder","type":"exact"},{"name":"Pestivirus disease or disorder","type":"exact"},{"name":"Pestivirus infection","type":"related"},{"name":"Pestivirus infectious disease","type":"exact"},{"name":"infection, Pestivirus","type":"related"},{"name":"infections, Pestivirus","type":"related"}],"termid":"MONDO:0005909","xrefs":{"Monarch":{"xref_id":"0005909"}}}


id: PBO:0111315
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial PRR repeat protein, implicated in mitochondrial gene expression","termid":"PBO:0111315"}


id: GO:0044761
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont inhibits or disrupts the normal execution of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.","definition_xrefs":["GOC:jl","PMID:37157163"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated suppression of host synaptic transmission","termid":"GO:0044759"},{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host cholinergic synaptic transmission","termid":"GO:0044760"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host cholinergic synaptic transmission","synonyms":[{"name":"negative regulation by symbiont of host cholinergic synaptic transmission","type":"exact"}],"termid":"GO:0044761"}


id: MONDO:0008568
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thyroid hormone plasma membrane transport defect","secondary_identifiers":["OMIM:188560","UMLS:C1861101","MEDGEN:396060","MESH:C536916"],"synonyms":[{"name":"hyperthyroxinemia, Eumetabolic, due to T4 plasma Membrane Transport defect","type":"exact"},{"name":"thyroid hormone plasma membrane transport defect","type":"exact"},{"name":"thyroid hormone resistance due to T4 plasma Membrane transport defect","type":"exact"}],"termid":"MONDO:0008568","xrefs":{"Monarch":{"xref_id":"0008568"}}}


id: PBO:0078918
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gln (anticodon TTG) 7-1","termid":"PBO:0078918"}


id: GO:0021737
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.","definition_xrefs":["GOC:dph","GO_REF:0000021","GOC:cls","GOC:curators","GOC:dgh","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neural nucleus development","termid":"GO:0048857"},{"relation_name":"part_of","term_name":"cerebellum development","termid":"GO:0021549"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"emboliform nucleus development","termid":"GO:0021737"}


id: PBO:0062341
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 6 subfamily J member 1","termid":"PBO:0062341"}


id: PBO:0071561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L35a pseudogene 27","termid":"PBO:0071561"}


id: GO:1904394
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.","definition_xrefs":["GO_REF:0000058","PMID:7722643","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of receptor clustering","termid":"GO:1903910"},{"relation_name":"is_a","term_name":"regulation of skeletal muscle acetylcholine-gated channel clustering","termid":"GO:1904393"},{"relation_name":"negatively_regulates","term_name":"skeletal muscle acetylcholine-gated channel clustering","termid":"GO:0071340"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of skeletal muscle acetylcholine-gated channel clustering","synonyms":[{"name":"down regulation of skeletal muscle AChR clustering","type":"exact"},{"name":"down regulation of skeletal muscle acetylcholine-gated channel clustering","type":"exact"},{"name":"down regulation of skeletal muscle nicotinic acetylcholine receptor clustering","type":"exact"},{"name":"down-regulation of skeletal muscle AChR clustering","type":"exact"},{"name":"down-regulation of skeletal muscle acetylcholine-gated channel clustering","type":"exact"},{"name":"down-regulation of skeletal muscle nicotinic acetylcholine receptor clustering","type":"exact"},{"name":"downregulation of skeletal muscle AChR clustering","type":"exact"},{"name":"downregulation of skeletal muscle acetylcholine-gated channel clustering","type":"exact"},{"name":"downregulation of skeletal muscle nicotinic acetylcholine receptor clustering","type":"exact"},{"name":"inhibition of skeletal muscle AChR clustering","type":"narrow"},{"name":"inhibition of skeletal muscle acetylcholine-gated channel clustering","type":"narrow"},{"name":"inhibition of skeletal muscle nicotinic acetylcholine receptor clustering","type":"narrow"},{"name":"negative regulation of skeletal muscle AChR clustering","type":"exact"},{"name":"negative regulation of skeletal muscle nicotinic acetylcholine receptor clustering","type":"exact"}],"termid":"GO:1904394"}


id: GO:0140761
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reactions: nucleoside 3',5'-cyclic AMP + H2O = AMP + H+; this activity is activated by binding to calcium-bound calmodulin.","definition_xrefs":["PMID:15901640"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3',5'-cyclic-AMP phosphodiesterase activity","termid":"GO:0004115"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016788"],"is_obsolete":false,"name":"calmodulin-activated 3',5'-cyclic-AMP phosphodiesterase activity","synonyms":[{"name":"calcium- and calmodulin-regulated 3',5'-cyclic-AMP phosphodiesterase activity","type":"broad"},{"name":"calcium- and calmodulin-regulated AMP-specific phosphodiesterase activity","type":"exact"},{"name":"calcium- and calmodulin-regulated cAMP phosphodiesterase activity","type":"related"},{"name":"calcium- and calmodulin-regulated cyclic-AMP phosphodiesterase activity","type":"exact"},{"name":"calcium/calmodulin-regulated cAMP-specific phosphodiesterase activity","type":"exact"}],"termid":"GO:0140761"}


id: PBO:0088840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vaculoar proteinase B inhibitor Pbi2","termid":"PBO:0088840"}


id: PBO:0071159
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L22 pseudogene 24","termid":"PBO:0071159"}


id: PBO:0013077
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"does not functionally complement E. coli hisB","termid":"PBO:0013077"}


id: MONDO:0017469
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital elbow dislocation","secondary_identifiers":["MEDGEN:539330","UMLS:C0265561","Orphanet:295032","GARD:21210","icd11.foundation:1593186141"],"synonyms":[{"name":"congenital radial head dislocation","type":"exact"},{"name":"isolated congenital elbow dislocation","type":"exact"},{"name":"isolated congenital radial head dislocation","type":"related"}],"termid":"MONDO:0017469","xrefs":{"Monarch":{"xref_id":"0017469"}}}


id: PBO:0073918
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 16 member 7","termid":"PBO:0073918"}


id: GO:0050117
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-acetyl-beta-alanine + H2O = beta-alanine + acetate.","definition_xrefs":["EC:3.5.1.21","RHEA:23212"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"},{"relation_name":"is_a","term_name":"deacetylase activity","termid":"GO:0019213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0019213"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0016810","GO:0003824","GO:0019213"],"is_obsolete":false,"name":"N-acetyl-beta-alanine deacetylase activity","secondary_identifiers":["KEGG_REACTION:R00909","MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN"],"synonyms":[{"name":"N-acetyl-beta-alanine amidohydrolase activity","type":"related"}],"termid":"GO:0050117"}


id: GO:0010009
data:
  {"annotated_genes":["SJAG_02587"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[90338],"is_not":false,"summary":null,"term":"GO:0010009"}]},"cv_name":"cellular_component","definition":"The side (leaflet) of the endosome membrane that faces the cytoplasm.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic side of membrane","termid":"GO:0098562"},{"relation_name":"part_of","term_name":"endosome membrane","termid":"GO:0010008"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02587":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005768"}],"interesting_parent_ids":["GO:0005768","GO:0005737","GO:0005575","GO:0031410"],"is_obsolete":false,"name":"cytoplasmic side of endosome membrane","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"external leaflet of endosome membrane","type":"exact"},{"name":"external side of endosome membrane","type":"exact"}],"termid":"GO:0010009","terms_by_termid":{"GO:0010009":null}}


id: MONDO:0007278
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cataract that has material basis in mutation in the region 14q22-q23.","definition_xrefs":["DOID:0110227","PMID:6694185"],"direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset non-syndromic cataract","termid":"MONDO:0011060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cataract 32 multiple types","secondary_identifiers":["OMIM:115650","MEDGEN:854634","UMLS:C3887926"],"synonyms":[{"name":"CTAA1","type":"narrow"},{"name":"CTPP5","type":"narrow"},{"name":"CTRCT32","type":"exact"},{"name":"anterior polar cataract 1","type":"narrow"},{"name":"cataract 32, multiple types","type":"related"},{"name":"cataract, anterior polar","type":"related"},{"name":"cataract, anterior polar, 1","type":"related"},{"name":"cataract, posterior polar, 5","type":"related"},{"name":"posterior polar cataract 5","type":"narrow"}],"termid":"MONDO:0007278","xrefs":{"Monarch":{"xref_id":"0007278"}}}


id: MONDO:0018134
data:
  {"annotated_genes":["SJAG_00938","SJAG_00108","SJAG_03960","SJAG_02453","SJAG_00115","SJAG_03011"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86797,86798],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008962"},{"annotations":[85893],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014885"},{"annotations":[85753],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011997"},{"annotations":[86846],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011683"},{"annotations":[84917],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014070"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of amino acid and other organic acid metabolism","termid":"MONDO:0019189"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00108":null,"SJAG_00115":null,"SJAG_00938":null,"SJAG_02453":null,"SJAG_03011":null,"SJAG_03960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"disorder of melanin metabolism","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:352728","GARD:21528","UMLS:C5680988","MEDGEN:1842889"],"termid":"MONDO:0018134","terms_by_termid":{"MONDO:0008962":null,"MONDO:0011683":null,"MONDO:0011997":null,"MONDO:0014070":null,"MONDO:0014885":null},"xrefs":{"Monarch":{"xref_id":"0018134"}}}


id: PBO:0045929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EF-hand domain containing 2","termid":"PBO:0045929"}


id: PBO:0056840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MGAT4 family member E, pseudogene","termid":"PBO:0056840"}


id: MONDO:1010054
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hyperparathyroidism that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endocrine system disorder, non-human animal","termid":"MONDO:1011317"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperparathyroidism, non-human animal","secondary_identifiers":["OMIA:000508"],"termid":"MONDO:1010054","xrefs":{"Monarch":{"xref_id":"1010054"}}}


id: GO:0004171
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine.","definition_xrefs":["EC:2.5.1.46"],"gene_count":0,"genotype_count":0,"name":"obsolete deoxyhypusine synthase activity (obsolete GO:0004171)","synonyms":[{"name":"[eIF-5A]-deoxyhypusine synthase","type":"related"},{"name":"deoxyhypusine synthase activity","type":"exact"}],"termid":"GO:0004171"}


id: MONDO:0019650
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"idiopathic steroid-sensitive nephrotic syndrome","termid":"MONDO:0019067"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"idiopathic steroid-sensitive nephrotic syndrome with minimal change","secondary_identifiers":["Orphanet:93207"],"synonyms":[{"name":"steroid-sensitive MCNS","type":"exact"}],"termid":"MONDO:0019650","xrefs":{"Monarch":{"xref_id":"0019650"}}}


id: PBO:0067088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 124, pseudogene","termid":"PBO:0067088"}


id: FYPO:0005082
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at long terminal repeat regions is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:21151114","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to chromatin during vegetative growth","termid":"FYPO:0001509"},{"relation_name":"is_a","term_name":"normal protein localization to chromosome at long terminal repeat","termid":"FYPO:0002575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0000257"],"is_obsolete":false,"name":"normal protein localization to chromatin at long terminal repeat","synonyms":[{"name":"normal protein localisation to chromatin at long terminal repeat","type":"exact"},{"name":"normal protein localization to chromatin at LTR","type":"exact"},{"name":"normal protein localization to chromatin at long terminal repeat during mitotic cell cycle","type":"related"},{"name":"normal protein localization to chromatin at long terminal repeat during vegetative growth","type":"exact"}],"termid":"FYPO:0005082"}


id: PBO:0030201
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_elongated_vegetative_cell_with_mitotic_cell_cycle_arrest_in_interphase","termid":"PBO:0030201"}


id: PBO:0068633
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4 small nuclear 13, pseudogene","termid":"PBO:0068633"}


id: PBO:0083111
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair, localizes to the nucleus; sumoylated; NTG2 has a paralog, NTG1, that arose from the whole genome duplication","termid":"PBO:0083111"}


id: SO:0002193
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The pseudogene has arisen by reverse transcription of a mRNA into cDNA, followed by reintegration into the genome. Therefore, it has lost any intron/exon structure, and it might have a pseudo-polyA-tail.","direct_ancestors":[{"relation_name":"is_a","term_name":"pseudogenic_rRNA","termid":"SO:0000777"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"processed_pseudogenic_rRNA","synonyms":[{"name":"INSDC_feature:rRNA","type":"broad"},{"name":"INSDC_qualifier:processed","type":"exact"},{"name":"processed pseudogenic rRNA","type":"exact"}],"termid":"SO:0002193"}


id: PBO:0083110
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress; required for maintaining mitochondrial genome integrity; NTG1 has a paralog, NTG2, that arose from the whole genome duplication","termid":"PBO:0083110"}


id: GO:0003166
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ventricular cardiac muscle tissue development","termid":"GO:0003229"},{"relation_name":"part_of","term_name":"His-Purkinje system development","termid":"GO:0003164"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"bundle of His development","synonyms":[{"name":"atrioventricular bundle development","type":"exact"}],"termid":"GO:0003166"}


id: PBO:0077241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane and coiled-coil domains 2","termid":"PBO:0077241"}


id: MONDO:0002395
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An adenoma arising from the renal cortex.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney benign neoplasm","termid":"MONDO:0002513"},{"relation_name":"is_a","term_name":"adenoma","termid":"MONDO:0004972"},{"relation_name":"is_a","term_name":"benign epithelial neoplasm","termid":"MONDO:0036976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"renal adenoma","secondary_identifiers":["DOID:2697","NCIT:C8383","MEDGEN:137794","UMLS:C0334684"],"synonyms":[{"name":"adenoma, renal cell, benign","type":"exact"},{"name":"kidney adenoma","type":"exact"},{"name":"renal adenoma","type":"exact"},{"name":"renal cell adenoma","type":"exact"},{"name":"renal cell adenoma (morphologic abnormality)","type":"exact"},{"name":"renal tubule adenoma","type":"exact"}],"termid":"MONDO:0002395","xrefs":{"Monarch":{"xref_id":"0002395"}}}


id: PBO:0027661
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-cut_during_cellular_response_to_methyl_methanesulfonate","termid":"PBO:0027661"}


id: GO:0010600
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.","definition_xrefs":["PMID:18287041"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of hormone biosynthetic process","termid":"GO:0046885"},{"relation_name":"is_a","term_name":"regulation of auxin metabolic process","termid":"GO:0090354"},{"relation_name":"regulates","term_name":"auxin biosynthetic process","termid":"GO:0009851"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of auxin biosynthetic process","termid":"GO:0010600"}


id: GO:0004219
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: pyroglutamyl-peptide + H2O = pyroglutamate + peptide.","definition_xrefs":["GOC:curator"],"gene_count":0,"genotype_count":0,"name":"obsolete pyroglutamyl-peptidase I activity (obsolete GO:0004219)","synonyms":[{"name":"pyroglutamyl-peptidase I activity","type":"exact"}],"termid":"GO:0004219"}


id: PBO:0000461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospholipase D, Pld1","termid":"PBO:0000461"}


id: PBO:0039894
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GDP dissociation inhibitor gamma","termid":"PBO:0039894"}


id: PBO:0034177
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_potential_to_developmentally_induce","termid":"PBO:0034177"}


id: GO:0140625
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the opioid growth factor (OGF, met-enkephalin) and transmitting the signal across the nuclear membrane. Met-enkephalin is an endogenous opioid peptide that binds to opioid and opioid growth factor receptors, regulating tissue growth in a variety of cellular processes.","definition_xrefs":["PMID:11890982"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptide receptor activity","termid":"GO:0001653"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"opioid growth factor receptor activity","synonyms":[{"name":"met-enkephalin receptor activity","type":"related"},{"name":"metenkefalin receptor activity","type":"related"},{"name":"methionine enkephalin receptor activity","type":"exact"}],"termid":"GO:0140625"}


id: PBO:0031042
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_cytoskeleton_organization","termid":"PBO:0031042"}


id: GO:1905280
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.","definition_xrefs":["GOC:TermGenie","GOC:PARL","GO_REF:0000058","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of intracellular transport","termid":"GO:0032387"},{"relation_name":"is_a","term_name":"regulation of retrograde transport, endosome to Golgi","termid":"GO:1905279"},{"relation_name":"negatively_regulates","term_name":"retrograde transport, endosome to Golgi","termid":"GO:0042147"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0016192","GO:0006810"],"is_obsolete":false,"name":"negative regulation of retrograde transport, endosome to Golgi","synonyms":[{"name":"down regulation of retrograde (endosome to Golgi) transport","type":"exact"},{"name":"down regulation of retrograde transport, endosome to Golgi","type":"exact"},{"name":"down-regulation of retrograde (endosome to Golgi) transport","type":"exact"},{"name":"down-regulation of retrograde transport, endosome to Golgi","type":"exact"},{"name":"downregulation of retrograde (endosome to Golgi) transport","type":"exact"},{"name":"downregulation of retrograde transport, endosome to Golgi","type":"exact"},{"name":"inhibition of retrograde (endosome to Golgi) transport","type":"narrow"},{"name":"inhibition of retrograde transport, endosome to Golgi","type":"narrow"},{"name":"negative regulation of retrograde (endosome to Golgi) transport","type":"exact"}],"termid":"GO:1905280"}


id: PBO:0038339
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_substance_added","termid":"PBO:0038339"}


id: GO:0004384
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: ATP + GMP = ADP + GDP, associated with the cell membrane.","definition_xrefs":["EC:2.7.4.8"],"gene_count":0,"genotype_count":0,"name":"obsolete membrane-associated guanylate kinase (obsolete GO:0004384)","synonyms":[{"name":"MAGUK","type":"exact"},{"name":"membrane-associated guanylate kinase","type":"exact"}],"termid":"GO:0004384"}


id: PBO:0049099
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 156","termid":"PBO:0049099"}


id: GO:0046776
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process by which a symbiont inhibits or disrupts the normal processing and presentation of a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, some viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.","definition_xrefs":["GOC:add","PMID:10859382","PMID:9175839","PMID:10227971","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated suppression of host antigen processing and presentation","termid":"GO:0039588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I","secondary_identifiers":["GO:0039591"],"synonyms":[{"name":"inhibition of host MHC class I molecule presentation by virus","type":"narrow"},{"name":"negative regulation by virus of MHC class I cell surface presentation","type":"narrow"},{"name":"suppression by virus of MHC class I cell surface presentation in host","type":"narrow"},{"name":"suppression by virus of host MHC class I cell surface presentation","type":"narrow"},{"name":"suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I","type":"narrow"},{"name":"suppression by virus of host tapasin activity","type":"narrow"}],"termid":"GO:0046776"}


id: GO:0106422
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: Zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal.","definition_xrefs":["PMID:19889630","PMID:19020100","RHEA:33931"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carotenoid dioxygenase activity","termid":"GO:0010436"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"carotenoid isomerooxygenase activity","secondary_identifiers":["EC:1.13.11.65"],"termid":"GO:0106422"}


id: PBO:0074196
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 39 member 6","termid":"PBO:0074196"}


id: PBO:0026785
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_ascus_morphology","termid":"PBO:0026785"}


id: PBO:0075013
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 115-24","termid":"PBO:0075013"}


id: FYPO:0007382
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of DNA binding at a transcription regulatory region by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal double-stranded DNA binding","termid":"FYPO:0007542"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000653"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000652","FYPO:0000653"],"is_obsolete":false,"name":"normal transcription regulatory region sequence-specific DNA binding","synonyms":[{"name":"normal promoter binding","type":"related"},{"name":"normal sequence-specific DNA binding at transcription regulatory region","type":"exact"},{"name":"normal transcription regulatory region binding","type":"exact"}],"termid":"FYPO:0007382"}


id: MONDO:0011289
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"apraxia of eyelid opening","secondary_identifiers":["UMLS:C1864184","MEDGEN:350360","OMIM:603119"],"synonyms":[{"name":"apraxia of eyelid opening","type":"exact"}],"termid":"MONDO:0011289","xrefs":{"Monarch":{"xref_id":"0011289"}}}


id: PBO:0089514
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RhoGAP Rga2","termid":"PBO:0089514"}


id: MONDO:0008004
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of mitral valve prolapse (disease) that is caused by an inherited modification of the individual's genome.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitral valve prolapse","termid":"MONDO:0004910"},{"relation_name":"is_a","term_name":"congenital mitral valve insufficiency and/or stenosis","termid":"MONDO:0019817"},{"relation_name":"is_a","term_name":"inherited mitral valve disease","termid":"MONDO:0042966"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"familial mitral valve prolapse","secondary_identifiers":["UMLS:C0340364","GARD:3687","MEDGEN:573696","Orphanet:741","SCTID:233858000","OMIMPS:157700"],"synonyms":[{"name":"MVP","type":"related"},{"name":"hereditary mitral valve prolapse (disease)","type":"exact"},{"name":"mitral valve prolapse, familial","type":"related"},{"name":"mitral valve prolapse, familial, autosomal dominant","type":"related"}],"termid":"MONDO:0008004","xrefs":{"Monarch":{"xref_id":"0008004"}}}


id: PBO:0000555
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"retromer complex subunit Vps17","termid":"PBO:0000555"}


id: PBO:0034692
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_lysophosphatidylcholine_level","termid":"PBO:0034692"}


id: GO:0009922
data:
  {"annotated_genes":["SJAG_01356","SJAG_02885"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[66195,77419],"is_not":false,"summary":null,"term":"GO:0009922"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a very-long-chain acyl-CoA + H+ + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA. This reaction is the first (condensation) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.","definition_xrefs":["PMID:16564093","PMID:19763486","RHEA:32727"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, transferring groups other than amino-acyl groups","termid":"GO:0016747"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01356":null,"SJAG_02885":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016746","GO:0016740"],"is_obsolete":false,"name":"fatty acid elongase activity","references_by_uniquename":{"GO_REF:0000003":null,"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-548800","Reactome:R-HSA-2046088","MetaCyc:RXN-7697","Reactome:R-HSA-2046094","Reactome:R-HSA-2046100","Reactome:R-HSA-548814","Reactome:R-HSA-2046083","Reactome:R-HSA-2046095","Reactome:R-HSA-548815","Reactome:R-HSA-2046090","EC:2.3.1.199","Reactome:R-HSA-548830"],"synonyms":[{"name":"ELOVL","type":"exact"},{"name":"condensing enzyme","type":"broad"},{"name":"elongation of very long chain fatty acids activity","type":"exact"},{"name":"very-long-chain 3-ketoacyl-CoA synthase","type":"exact"},{"name":"very-long-chain 3-oxoacyl-CoA synthase","type":"exact"},{"name":"very-long-chain beta-ketoacyl-CoA synthase","type":"exact"}],"termid":"GO:0009922","terms_by_termid":{"GO:0009922":null}}


id: MONDO:0001779
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign papillary neoplasm that arises from the vagina and is characterized by the presence of a fibrovascular stalk lined by normal squamous epithelium. There is no evidence of atypia or relation to human papillomavirus.","definition_xrefs":["NCIT:C6374"],"direct_ancestors":[{"relation_name":"is_a","term_name":"benign vaginal neoplasm","termid":"MONDO:0000647"},{"relation_name":"is_a","term_name":"vaginal squamous tumor","termid":"MONDO:0001806"},{"relation_name":"is_a","term_name":"squamous papilloma","termid":"MONDO:0001825"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vaginal squamous papilloma","secondary_identifiers":["UMLS:C1336943","DOID:137","MEDGEN:234983"],"synonyms":[{"name":"squamous papilloma of the vagina","type":"exact"},{"name":"squamous papilloma of vagina","type":"exact"},{"name":"vagina squamous papilloma","type":"exact"},{"name":"vaginal squamous papilloma","type":"exact"}],"termid":"MONDO:0001779","xrefs":{"Monarch":{"xref_id":"0001779"}}}


id: GO:0017126
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.","definition_xrefs":["ISBN:0198506732","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleolus organization","termid":"GO:0007000"},{"relation_name":"is_a","term_name":"cellular component biogenesis","termid":"GO:0044085"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"nucleologenesis","synonyms":[{"name":"nucleolus assembly","type":"narrow"},{"name":"nucleolus biogenesis","type":"exact"}],"termid":"GO:0017126"}


id: MONDO:1011728
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease, non-human animal","termid":"MONDO:1011724"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin G2 deficiency, non-human animal","secondary_identifiers":["OMIA:000555"],"termid":"MONDO:1011728","xrefs":{"Monarch":{"xref_id":"1011728"}}}


id: PBO:0026800
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_proteasome_core_complex_binding","termid":"PBO:0026800"}


id: GO:0097146
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.","definition_xrefs":["GOC:so","PMID:14634621"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Bcl-2 family protein complex","termid":"GO:0097136"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"NOXA-BCL-xl complex","termid":"GO:0097146"}


id: GO:0097550
data:
  {"annotated_genes":["SJAG_03206","SJAG_01523","SJAG_03120"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[70109,77023,77371],"is_not":false,"summary":null,"term":"GO:0097550"}]},"cv_name":"cellular_component","definition":"A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.","definition_xrefs":["GOC:di","PMID:22751016"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-DNA complex","termid":"GO:0032993"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01523":null,"SJAG_03120":null,"SJAG_03206":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"transcription preinitiation complex","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"DNA-templated transcriptional preinitiation complex","type":"exact"},{"name":"PIC","type":"narrow"},{"name":"preinitiation complex","type":"narrow"},{"name":"transcriptional pre-initiation complex","type":"exact"},{"name":"transcriptional preinitiation complex","type":"exact"}],"termid":"GO:0097550","terms_by_termid":{"GO:0097550":null}}


id: PBO:0078280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Cys (anticodon GCA) 13-1","termid":"PBO:0078280"}


id: PBO:0001528
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOR signaling pathway transcriptional corepressor Crf1 (predicted)","termid":"PBO:0001528"}


id: MONDO:0006387
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A diffuse large B-cell lymphoma that is localized to the lungs at the time of presentation. Signs and symptoms include cough, dyspnea, and hemoptysis.","definition_xrefs":["NCIT:C45605"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune system cancer","termid":"MONDO:0000621"},{"relation_name":"is_a","term_name":"diffuse large B-cell lymphoma","termid":"MONDO:0018905"},{"relation_name":"is_a","term_name":"lung non-Hodgkin lymphoma","termid":"MONDO:0020644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004992","MONDO:0005570"],"is_obsolete":false,"name":"primary pulmonary diffuse large B-cell lymphoma","secondary_identifiers":["EFO:1000495","MEDGEN:1789549","UMLS:C2200138"],"synonyms":[{"name":"diffuse large B-cell lymphoma of lung","type":"exact"},{"name":"high grade MALT lymphoma of the lung","type":"exact"},{"name":"lung diffuse large B-cell lymphoma","type":"exact"},{"name":"primary pulmonary diffuse large B-cell lymphoma","type":"exact"},{"name":"pulmonary diffuse large B-cell lymphoma","type":"exact"}],"termid":"MONDO:0006387","xrefs":{"Monarch":{"xref_id":"0006387"}}}


id: PBO:0091060
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial tRNA(Ile)-lysidine synthetase Til1","termid":"PBO:0091060"}


id: PBO:0030501
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_mitotic_cell_cycle_checkpoint","termid":"PBO:0030501"}


id: SO:0001255
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A polyploid where the multiple chromosome set was derived from the same organism.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyploid","termid":"SO:0001254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autopolyploid","secondary_identifiers":["http://en.wikipedia.org/wiki/Autopolyploid"],"termid":"SO:0001255"}


id: MONDO:0015330
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete overgrowth/obesity syndrome (obsolete MONDO:0015330)","secondary_identifiers":["Orphanet:139024"],"termid":"MONDO:0015330","xrefs":{"Monarch":{"xref_id":"0015330"}}}


id: PBO:0056599
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"midkine","termid":"PBO:0056599"}


id: PBO:0038448
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alanyl-tRNA synthetase 1","termid":"PBO:0038448"}


id: FYPO:0005078
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of canavanine and rapamycin. Cells stop growing (and may die) at concentrations of canavanine and rapamycin that allows wild type cells to grow.","definition_xrefs":["PMID:17179073","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0002683","FYPO:0001985","FYPO:0000139","FYPO:0005447","FYPO:0000003"],"is_obsolete":false,"name":"sensitive to canavanine and rapamycin","synonyms":[{"name":"hypersensitive to canavanine and rapamycin","type":"exact"},{"name":"sensitive to canavanine and rapamycin during mitotic cell cycle","type":"related"},{"name":"sensitive to canavanine and rapamycin during vegetative growth","type":"exact"},{"name":"sensitive to canavanine and rapamycin in combination","type":"exact"}],"termid":"FYPO:0005078"}


id: MONDO:0007624
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Flynn-Aird syndrome is a neuroectodermal disorder involving the nervous, cutaneous, skeletal, and glandular systems. It has been described in 10 members from five generations of one family. Clinical manifestations include eye abnormalities (cataracts, retinitis pigmentosa, and myopia), sensorineural deafness, ataxia, peripheral neuritis, epilepsy, dementia, skin atrophy and striking dental caries. Patients also present with muscle wasting, joint stiffness and bone cysts. Flynn-Aird syndrome is transmitted as an autosomal dominant trait. It shows some similarities to the syndromes of Werner, Refsum and Cockayne.","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete genetic nervous system disorder (obsolete MONDO:0019117)","termid":"MONDO:0019117"},{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"premature aging syndrome","termid":"MONDO:0019303"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0019303"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0019303"],"is_obsolete":false,"name":"Flynn-Aird syndrome","secondary_identifiers":["MESH:C537066","OMIM:136300","GARD:2347","MEDGEN:91009","Orphanet:2047","SCTID:239056006","UMLS:C0343108"],"synonyms":[{"name":"Flynn Aird syndrome","type":"related"},{"name":"Flynn-Aird syndrome","type":"exact"},{"name":"cataracts, retinitis pigmentosa, sensorineural hearing loss, ataxia, peripheral neuritis, epilepsy, dementia, skin atrophy, chronic ulceration, dental","type":"related"}],"termid":"MONDO:0007624","xrefs":{"Monarch":{"xref_id":"0007624"}}}


id: PBO:0057903
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3591","termid":"PBO:0057903"}


id: GO:0003242
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"growth involved in heart morphogenesis","termid":"GO:0003241"},{"relation_name":"part_of","term_name":"cardiac chamber morphogenesis","termid":"GO:0003206"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac chamber ballooning","termid":"GO:0003242"}


id: MONDO:0005451
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake.","definition_xrefs":["NCIT:C89332"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"specific developmental disorder","termid":"MONDO:0000592"},{"relation_name":"is_a","term_name":"psychiatric disorder","termid":"MONDO:0002025"},{"relation_name":"is_a","term_name":"nutritional disorder","termid":"MONDO:0005137"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eating disorder","secondary_identifiers":["ICD9:307.59","UMLS:C0013473","SCTID:72366004","MEDGEN:4434","DOID:8670","EFO:0005203","ICD9:307.50"],"synonyms":[{"name":"eating disorder","type":"exact"},{"name":"feeding and eating disorder","type":"exact"}],"termid":"MONDO:0005451","xrefs":{"Monarch":{"xref_id":"0005451"}}}


id: PBO:0077460
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMEM184B antisense RNA 1","termid":"PBO:0077460"}


id: GO:0002624
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of antigen processing and presentation","termid":"GO:0002579"},{"relation_name":"is_a","term_name":"regulation of B cell antigen processing and presentation","termid":"GO:0002622"},{"relation_name":"positively_regulates","term_name":"B cell antigen processing and presentation","termid":"GO:0002450"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of B cell antigen processing and presentation","synonyms":[{"name":"activation of B cell antigen processing and presentation","type":"narrow"},{"name":"positive regulation of B lymphocyte antigen processing and presentation","type":"exact"},{"name":"positive regulation of B-cell antigen processing and presentation","type":"exact"},{"name":"positive regulation of B-lymphocyte antigen processing and presentation","type":"exact"},{"name":"stimulation of B cell antigen processing and presentation","type":"narrow"},{"name":"up regulation of B cell antigen processing and presentation","type":"exact"},{"name":"up-regulation of B cell antigen processing and presentation","type":"exact"},{"name":"upregulation of B cell antigen processing and presentation","type":"exact"}],"termid":"GO:0002624"}


id: PBO:0078164
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha variable 41","termid":"PBO:0078164"}


id: PATO:0000254
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000254 vibrissae reflex (obsolete PATO:0000254)","termid":"PATO:0000254"}


id: RO:0002517
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"inverse of has start sequence","direct_ancestors":[{"relation_name":"is_a","term_name":"is_subsequence_of","termid":"RO:0002525"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"is_start_sequence_of","termid":"RO:0002517"}


id: FYPO:0009102
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain less cytoplasmic microtubules than normal during interphase of the mitotic cell cycle.","direct_ancestors":[{"relation_name":"is_a","term_name":"microtubules present in decreased numbers","termid":"FYPO:0003430"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002399"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002399","FYPO:0000054","FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"interphase microtubules present in decreased numbers","synonyms":[{"name":"decreased number of interphase microtubules","type":"exact"},{"name":"fewer microtubules present during mitotic interphase","type":"exact"}],"termid":"FYPO:0009102"}


id: GO:0047699
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + nonane-4,6-dione = butanoate + H+ + pentan-2-one.","definition_xrefs":["RHEA:11908"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances","termid":"GO:0016823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"beta-diketone hydrolase activity","secondary_identifiers":["EC:3.7.1.7","KEGG_REACTION:R03781","MetaCyc:BETA-DIKETONE-HYDROLASE-RXN"],"synonyms":[{"name":"b-diketone hydrolase activity","type":"exact"},{"name":"nonane-4,6-dione acylhydrolase activity","type":"related"},{"name":"oxidized PVA hydrolase activity","type":"related"}],"termid":"GO:0047699"}


id: PBO:0075398
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SP110 nuclear body protein","termid":"PBO:0075398"}


id: internal:interim
data:
  {"annotation_feature_type":"gene","cv_name":"synonym_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interim","termid":"internal:interim"}


id: GO:0048012
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by a ligand binding to a hepatocyte growth factor receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:ceb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell surface receptor protein tyrosine kinase signaling pathway","termid":"GO:0007169"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"hepatocyte growth factor receptor signaling pathway","secondary_identifiers":["Reactome:R-HSA-8852405"],"synonyms":[{"name":"HGF receptor signaling pathway","type":"exact"},{"name":"HGF receptor signalling pathway","type":"exact"},{"name":"Met signaling pathway","type":"narrow"}],"termid":"GO:0048012"}


id: GO:0048675
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Long distance growth of a single axon process involved in cellular development.","definition_xrefs":["GOC:dph","GOC:lm","GOC:dgh","GOC:rl","GOC:jid","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron projection extension","termid":"GO:1990138"},{"relation_name":"part_of","term_name":"axonogenesis","termid":"GO:0007409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"axon extension","secondary_identifiers":["GO:0048676"],"synonyms":[{"name":"axon extension involved in development","type":"exact"}],"termid":"GO:0048675"}


id: PR:Q10333
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pex11 gene.","definition_xrefs":["UniProtKB:Q10333","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxisomal biogenesis factor 11 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC582.09","synonyms":[{"name":"Spom972h-pex11","type":"exact"}],"termid":"PR:Q10333"}


id: PBO:0076140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"succinate-CoA ligase GDP-forming subunit beta","termid":"PBO:0076140"}


id: MONDO:0009763
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypoventilation syndrome in very obese persons with excessive adipose tissue around the abdomen and diaphragm is characterized by diminished to absent ventilatory chemoresponsiveness; chronic hypoxia; hypercapnia; polycythemia; and long periods of sleep during day and night (hypersomnolence). It is a condition often related to obstructive sleep apnea but can occur separately.","definition_xrefs":["MESH:D010845"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"obesity-hypoventilation syndrome","secondary_identifiers":["EFO:1001382","ICD9:786.09","MEDGEN:18472","NANDO:1200752","OMIM:257500","SCTID:190966007","UMLS:C0031880"],"synonyms":[{"name":"Pickwickian syndrome","type":"related"},{"name":"obesity-hypoventilation syndrome","type":"exact"}],"termid":"MONDO:0009763","xrefs":{"Monarch":{"xref_id":"0009763"}}}


id: PBO:0043300
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-type lectin domain family 18 member B","termid":"PBO:0043300"}


id: PBO:0051433
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable 3-15 (pseudogene)","termid":"PBO:0051433"}


id: SO:0001122
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A motif of two consecutive residues with dihedral angles: Residue(i): -140 degrees < phi < -20 degrees, -90 degrees < psi < +40 degrees. Residue(i+1): +20 degrees < phi < +140 degrees, -40 degrees < psi < +90 degrees.","definition_xrefs":["EBIBS:GAR"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polypeptide_nest_motif","termid":"SO:0001120"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"polypeptide_nest_right_left_motif","secondary_identifiers":["BS:00225"],"synonyms":[{"name":"nest_right_left","type":"exact"},{"name":"nest_rl","type":"exact"},{"name":"polypeptide nest right left motif","type":"exact"}],"termid":"SO:0001122"}


id: GO:0006757
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete ATP generation from ADP (obsolete GO:0006757)","synonyms":[{"name":"ADP phosphorylation","type":"exact"}],"termid":"GO:0006757"}


id: GO:1902700
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol.","definition_xrefs":["GO_REF:0000093","GOC:TermGenie","PMID:18727018","PMID:19539744","GOC:mengo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete pentose catabolic process to butan-1-ol (obsolete GO:1902700)","synonyms":[{"name":"pentose breakdown to butan-1-ol","type":"exact"},{"name":"pentose catabolic process to 1-butanol","type":"exact"},{"name":"pentose catabolic process to butanol","type":"exact"},{"name":"pentose catabolism to butan-1-ol","type":"exact"},{"name":"pentose degradation to butan-1-ol","type":"exact"},{"name":"solventogenesis","type":"broad"}],"termid":"GO:1902700"}


id: PBO:0039301
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ALG14 UDP-N-acetylglucosaminyltransferase subunit","termid":"PBO:0039301"}


id: MONDO:1010917
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Myopathy that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myopathy, non-human animal","termid":"MONDO:1010195"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myopathy, dog","secondary_identifiers":["OMIA:000693-9615"],"termid":"MONDO:1010917","xrefs":{"Monarch":{"xref_id":"1010917"}}}


id: PBO:0079459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trans-golgi network vesicle protein 23 homolog A","termid":"PBO:0079459"}


id: PBO:0080876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"yippee like 2","termid":"PBO:0080876"}


id: MONDO:1011800
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"contractural arachnodactyly, non-human animal","secondary_identifiers":["OMIA:001511"],"termid":"MONDO:1011800","xrefs":{"Monarch":{"xref_id":"1011800"}}}


id: PBO:0000530
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"6.3.2.2","termid":"PBO:0000530"}


id: MONDO:0003997
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A Kaposi sarcoma arising from the colon.","definition_xrefs":["NCIT:C5516"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colon sarcoma","termid":"MONDO:0003352"},{"relation_name":"is_a","term_name":"colorectal Kaposi sarcoma","termid":"MONDO:0024659"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"colon Kaposi sarcoma","secondary_identifiers":["UMLS:C1333091","MEDGEN:232378","DOID:6804"],"synonyms":[{"name":"Kaposi's sarcoma (disease) of colon","type":"exact"},{"name":"Kaposi's sarcoma of colon","type":"exact"},{"name":"Kaposi's sarcoma of the colon","type":"exact"},{"name":"colon Kaposi sarcoma","type":"exact"},{"name":"colon Kaposi's sarcoma","type":"exact"},{"name":"colon Kaposi's sarcoma (disease)","type":"exact"},{"name":"colon Kaposis sarcoma","type":"exact"},{"name":"colonic Kaposi sarcoma","type":"exact"},{"name":"colonic Kaposi's sarcoma","type":"exact"},{"name":"colonic Kaposis sarcoma","type":"exact"}],"termid":"MONDO:0003997","xrefs":{"Monarch":{"xref_id":"0003997"}}}


id: PBO:0073921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 16 member 10","termid":"PBO:0073921"}


id: GO:0015614
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) = ADP + phosphate + D-xylose(in).","definition_xrefs":["RHEA:29899"],"direct_ancestors":[{"relation_name":"is_a","term_name":"D-xylose transmembrane transporter activity","termid":"GO:0015148"},{"relation_name":"is_a","term_name":"ABC-type monosaccharide transporter activity","termid":"GO:0015407"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"ABC-type D-xylose transporter activity","secondary_identifiers":["EC:7.5.2.10","MetaCyc:ABC-33-RXN"],"synonyms":[{"name":"ATPase-coupled D-xylose transmembrane transporter activity","type":"related"},{"name":"D-xylose porter activity","type":"broad"},{"name":"D-xylose-importing ATPase activity","type":"related"}],"termid":"GO:0015614"}


id: FYPO:0005244
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing arabinose as the carbon source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased vegetative cell population growth","termid":"FYPO:0001355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0002060","FYPO:0001985","FYPO:0002057","FYPO:0002058","FYPO:0000139","FYPO:0005447","FYPO:0000003"],"is_obsolete":false,"name":"decreased cell population growth on arabinose carbon source","synonyms":[{"name":"decreased growth on arabinose carbon source","type":"broad"},{"name":"decreased vegetative cell growth on arabinose carbon source","type":"exact"},{"name":"reduced cell growth on arabinose carbon source","type":"related"},{"name":"slow cell growth on arabinose carbon source","type":"narrow"}],"termid":"FYPO:0005244"}


id: MONDO:0020295
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Aberrant drainage of one or more of the pulmonary veins which causes the return of oxygen-rich blood to the right atrium.","definition_xrefs":["NCIT:C110942"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital heart disease","termid":"MONDO:0005453"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"congenital pulmonary veins anomaly","secondary_identifiers":["GARD:19559","SCTID:111322000","Orphanet:98729"],"synonyms":[{"name":"congenital anomaly of pulmonary veins","type":"exact"},{"name":"pulmonary vein abnormality","type":"related"}],"termid":"MONDO:0020295","xrefs":{"Monarch":{"xref_id":"0020295"}}}


id: PBO:0051754
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol hexakisphosphate kinase 3","termid":"PBO:0051754"}


id: PBO:0077789
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA topoisomerase III beta pseudogene 1","termid":"PBO:0077789"}


id: GO:0120209
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.","definition_xrefs":["GOC:krc","PMID:29127712","GOC:cvs"],"direct_ancestors":[{"relation_name":"is_a","term_name":"telodendria","termid":"GO:0120208"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"cone telodendria","termid":"GO:0120209"}


id: PBO:0079777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP-glucose glycoprotein glucosyltransferase 2","termid":"PBO:0079777"}


id: PBO:0039828
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arginase 2","termid":"PBO:0039828"}


id: PBO:0053077
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LBX2 antisense RNA 1","termid":"PBO:0053077"}


id: PBO:0085961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; overexpression confers resistance to the antimicrobial peptide MiAMP1 and causes growth arrest, apoptosis, and increased sensitivity to cobalt chloride","termid":"PBO:0085961"}


id: GO:0045315
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of eye photoreceptor cell development","termid":"GO:0042479"},{"relation_name":"is_a","term_name":"regulation of compound eye photoreceptor development","termid":"GO:0045314"},{"relation_name":"positively_regulates","term_name":"compound eye photoreceptor development","termid":"GO:0042051"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of compound eye photoreceptor development","synonyms":[{"name":"activation of eye photoreceptor development","type":"broad"},{"name":"positive regulation of eye photoreceptor development","type":"broad"},{"name":"stimulation of eye photoreceptor development","type":"broad"},{"name":"up regulation of eye photoreceptor development","type":"broad"},{"name":"up-regulation of eye photoreceptor development","type":"broad"},{"name":"upregulation of eye photoreceptor development","type":"broad"}],"termid":"GO:0045315"}


id: PBO:0083931
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B; homologous to mammalian ribosomal protein S27A, no bacterial homolog","termid":"PBO:0083931"}


id: _global:enables
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"c enables p iff c is capable of p and c acts to execute p.","direct_ancestors":[{"relation_name":"is_a","term_name":"capable_of","termid":"_global:capable_of"},{"relation_name":"is_a","term_name":"go_annotation_extension_relation","termid":"_global:go_annotation_extension_relation"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enables","secondary_identifiers":["RO:0002327"],"termid":"_global:enables"}


id: PBO:0001932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein Nob1 (predicted)","termid":"PBO:0001932"}


id: PBO:0042504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDH23 antisense RNA 1","termid":"PBO:0042504"}


id: GO:0098756
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to cytokine","termid":"GO:0034097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to interleukin-21","synonyms":[{"name":"response to IL-21","type":"exact"}],"termid":"GO:0098756"}


id: GO:1904601
data:
  {"annotated_genes":["SJAG_00938","SJAG_03011"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[107888,115923],"is_not":false,"summary":null,"term":"GO:1904601"}]},"cv_name":"biological_process","definition":"A process in which a protein is transported to a location within an actin fusion focus.","definition_xrefs":["GOC:TermGenie","GO_REF:0000087","PMID:25825517"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein transport","termid":"GO:0015031"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00938":null,"SJAG_03011":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"protein transport to mating projection actin fusion focus","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"protein localisation in actin fusion focus","type":"exact"},{"name":"protein localisation to actin fusion focus","type":"exact"},{"name":"protein localization in actin fusion focus","type":"exact"}],"termid":"GO:1904601","terms_by_termid":{"GO:1904601":null}}


id: PATO:0001752
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A heterochronic growth quality inhering in an organism, structure, or group of organisms by virtue of the bearer's increased growth.","definition_xrefs":["PATOC:mh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heterochronic growth","termid":"PATO:0001490"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peramorphic growth","synonyms":[{"name":"hyperplastic growth","type":"exact"}],"termid":"PATO:0001752"}


id: GO:0003906
data:
  {"annotated_genes":["SJAG_03665","SJAG_03724","SJAG_02298"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[72933,79702],"is_not":false,"summary":null,"term":"GO:0003906"},{"annotations":[65316],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140078"}]},"cv_name":"molecular_function","definition":"Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).","definition_xrefs":["Wikipedia:AP_endonuclease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic activity, acting on DNA","termid":"GO:0140097"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02298":null,"SJAG_03665":null,"SJAG_03724":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140097","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"DNA-(apurinic or apyrimidinic site) endonuclease activity","references_by_uniquename":{"GO_REF:0000003":null,"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-5649725","Reactome:R-HSA-5649711","Reactome:R-HSA-110375"],"synonyms":[{"name":"AP deoxyendoribonuclease activity","type":"exact"},{"name":"UV endonuclease","type":"broad"},{"name":"abasic deoxyendoribonuclease activity","type":"exact"},{"name":"apurinic deoxyendoribonuclease activity","type":"exact"},{"name":"apurinic/apyrimidinic endodeoxyribonuclease activity","type":"exact"},{"name":"apyrimidinic deoxyendoribonuclease activity","type":"exact"},{"name":"deoxyribonuclease (apurinic or apyrimidinic) activity","type":"exact"},{"name":"endonuclease VIII activity","type":"related"}],"termid":"GO:0003906","terms_by_termid":{"GO:0003906":null,"GO:0140078":null}}


id: GO:0080005
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis.","definition_xrefs":["PMID:11607105"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of photosynthesis","termid":"GO:0010109"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"photosystem stoichiometry adjustment","termid":"GO:0080005"}


id: PATO:0002184
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Cyclic cyclicity inheres in a molecule when the atoms of the molecule do contain at least one cycle in the atom-atom connection paths (through bonds).","definition_xrefs":["PATOC:JH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cyclicity","termid":"PATO:0002183"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclic cyclicity","termid":"PATO:0002184"}


id: GO:0044195
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport.","definition_xrefs":["PMID:17959832","GOC:jl","PMID:9024685"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"nuclear envelope","termid":"GO:0005635"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005575","GO:0005634"],"is_obsolete":false,"name":"nucleoplasmic reticulum","synonyms":[{"name":"nuclear channels","type":"exact"}],"termid":"GO:0044195"}


id: PBO:0028516
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_oxidation_during_cellular_response_to_hydrogen_peroxide","termid":"PBO:0028516"}


id: FYPO:0005814
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus ends of microtubules does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to microtubule during vegetative growth","termid":"FYPO:0003269"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to microtubule plus-end","synonyms":[{"name":"abolished protein localisation to microtubule plus-end","type":"exact"},{"name":"abolished protein localization to microtubule plus end","type":"exact"},{"name":"abolished protein localization to microtubule plus-end during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to microtubule plus-end during vegetative growth","type":"exact"},{"name":"protein localization to microtubule plus-end abolished","type":"exact"}],"termid":"FYPO:0005814"}


id: PBO:0055368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2797","termid":"PBO:0055368"}


id: GO:0009075
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete histidine family amino acid metabolic process (obsolete GO:0009075)","synonyms":[{"name":"histidine family amino acid metabolic process","type":"exact"},{"name":"histidine family amino acid metabolism","type":"exact"}],"termid":"GO:0009075"}


id: PBO:0047657
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FKBP prolyl isomerase 9","termid":"PBO:0047657"}


id: PBO:0085820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; expressed during diauxic shift and stationary phase, and negatively regulated by glucose; expression is regulated by Msn2p/Msn4p; overexpression slows down progression through meiosis and improves fermentative efficiency; YNR034W-A has a paralog, YCR075W-A, that arose from the whole genome duplication","termid":"PBO:0085820"}


id: MONDO:0017301
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pericardial and diaphragmatic defect is a rare combination of absent pericardium with congenital diaphragmatic defect.","definition_xrefs":["Orphanet:2847"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pericardial and diaphragmatic defect","secondary_identifiers":["GARD:18780","MEDGEN:1373904","UMLS:C4510305"],"termid":"MONDO:0017301","xrefs":{"Monarch":{"xref_id":"0017301"}}}


id: PBO:0056867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule associated monooxygenase, calponin and LIM domain containing 3","termid":"PBO:0056867"}


id: PBO:0065166
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein interacting with cyclin A1","termid":"PBO:0065166"}


id: GO:0048741
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.","definition_xrefs":["GOC:mtg_muscle","GOC:dph","GOC:jid","GOC:lm","GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myotube cell development","termid":"GO:0014904"},{"relation_name":"part_of","term_name":"skeletal muscle tissue development","termid":"GO:0007519"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"skeletal muscle fiber development","synonyms":[{"name":"skeletal muscle fibre development","type":"exact"},{"name":"skeletal myofiber development","type":"exact"},{"name":"skeletal myofibre development","type":"exact"}],"termid":"GO:0048741"}


id: PBO:0017085
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces pombe specific protein Mug112","termid":"PBO:0017085"}


id: FYPO:0005615
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal during a cellular response to bleomycin.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein phosphorylation during vegetative growth","termid":"FYPO:0000775"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0002494","FYPO:0005447","FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"abnormal protein phosphorylation during cellular response to bleomycin","synonyms":[{"name":"abnormal protein phosphorylation during cellular response to bleomycin during mitotic cell cycle","type":"related"},{"name":"abnormal protein phosphorylation during cellular response to bleomycin during vegetative growth","type":"exact"}],"termid":"FYPO:0005615"}


id: GO:0009495
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete thioredoxin-like 2Fe-2S ferredoxin (obsolete GO:0009495)","synonyms":[{"name":"thioredoxin-like 2Fe-2S ferredoxin","type":"exact"}],"termid":"GO:0009495"}


id: GO:0047741
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: benzyl cetraxate + H2O = benzyl alcohol + cetraxate + H+.","definition_xrefs":["RHEA:23460","EC:3.1.1.70"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016787","GO:0016788","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"cetraxate benzylesterase activity","secondary_identifiers":["KEGG_REACTION:R03612","MetaCyc:CETRAXATE-BENZYLESTERASE-RXN"],"synonyms":[{"name":"cetraxate-benzyl-ester benzylhydrolase activity","type":"related"}],"termid":"GO:0047741"}


id: MONDO:0011780
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"specific language impairment","termid":"MONDO:0000724"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"specific language impairment 3","secondary_identifiers":["UMLS:C1846719","OMIM:607134","MEDGEN:375953"],"synonyms":[{"name":"SLI3","type":"exact"},{"name":"specific language impairment 3","type":"exact"},{"name":"specific language impairment QTL, 3","type":"exact"},{"name":"specific language impairment quantitative trait locus on chromosome 13","type":"related"}],"termid":"MONDO:0011780","xrefs":{"Monarch":{"xref_id":"0011780"}}}


id: GO:0035910
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.","definition_xrefs":["UBERON:0001496","GOC:dgh","GOC:bf","MA:0002570","Wikipedia:Ascending_aorta"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"part_of","term_name":"ascending aorta development","termid":"GO:0035905"},{"relation_name":"part_of","term_name":"aorta morphogenesis","termid":"GO:0035909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ascending aorta morphogenesis","termid":"GO:0035910"}


id: PBO:0046802
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coagulation factor VIII","termid":"PBO:0046802"}


id: PBO:0048890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A6 family like 10","termid":"PBO:0048890"}


id: PBO:0070624
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7 like 1 pseudogene 8","termid":"PBO:0070624"}


id: PBO:0078741
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA methyltransferase 2 homolog B","termid":"PBO:0078741"}


id: PBO:0082945
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic inorganic pyrophosphatase (PPase); homodimer that catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase","termid":"PBO:0082945"}


id: GO:0009693
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.","definition_xrefs":["ISBN:0387969845"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ethylene metabolic process","termid":"GO:0009692"},{"relation_name":"is_a","term_name":"alkene biosynthetic process","termid":"GO:0043450"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ethylene biosynthetic process","secondary_identifiers":["GO:0042456","MetaCyc:ETHYL-PWY"],"synonyms":[{"name":"ethene biosynthesis","type":"exact"},{"name":"ethene biosynthesis from L-methionine","type":"exact"},{"name":"ethene biosynthetic process","type":"exact"},{"name":"ethene biosynthetic process from L-methionine","type":"exact"},{"name":"ethylene anabolism","type":"exact"},{"name":"ethylene biosynthesis","type":"exact"},{"name":"ethylene biosynthesis from L-methionine","type":"exact"},{"name":"ethylene biosynthetic process from L-methionine","type":"exact"},{"name":"ethylene formation","type":"exact"},{"name":"ethylene synthesis","type":"exact"}],"termid":"GO:0009693"}


id: PBO:0050497
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homeobox B7","termid":"PBO:0050497"}


id: MONDO:0011028
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive limb-girdle muscular dystrophy type 2F (LGMD2F) is a subtype of autosomal recessive limb-girdle muscular dystrophy characterized by a variable age of onset of progressive weakness and wasting of the proximal skeletal muscles of the shoulder and pelvic girdles, frequently associated with progressive respiratory muscle impairment and cardiomyopathy. Calf hypertrophy, muscle cramps and elevated serum creatine kinase levels are also observed. Neuropsychomotor development is usually normal.","definition_xrefs":["Orphanet:219"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive limb-girdle muscular dystrophy","termid":"MONDO:0015152"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of delta-sarcoglycan","termid":"MONDO:0016144"},{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0005267","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive limb-girdle muscular dystrophy type 2F","secondary_identifiers":["MESH:C535896","MEDGEN:331308","DOID:0110280","GARD:8573","OMIM:601287","SCTID:718177001","UMLS:C1832525"],"synonyms":[{"name":"LGMD2F","type":"exact"},{"name":"SGCD autosomal recessive limb-girdle muscular dystrophy","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy caused by mutation in SGCD","type":"exact"},{"name":"delta-sarcoglycanopathy","type":"broad"},{"name":"limb-girdle muscular dystrophy due to delta-sarcoglycan deficiency","type":"exact"},{"name":"limb-girdle muscular dystrophy type 2F","type":"related"},{"name":"muscular dystrophy limb-girdle with delta-sarcoglyan deficiency","type":"related"},{"name":"muscular dystrophy, limb-girdle, autosomal recessive 6","type":"exact"},{"name":"muscular dystrophy, limb-girdle, type 2F","type":"related"}],"termid":"MONDO:0011028","xrefs":{"Monarch":{"xref_id":"0011028"}}}


id: MONDO:0014927
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Joubert syndrome in which the cause of the disease is a mutation in the B9D1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Joubert syndrome","termid":"MONDO:0018772"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Joubert syndrome 27","secondary_identifiers":["GARD:16194","OMIM:617120","MEDGEN:934673","UMLS:C4310706","DOID:0110996"],"synonyms":[{"name":"B9D1 Joubert syndrome","type":"exact"},{"name":"JBTS27","type":"exact"},{"name":"Joubert syndrome 27","type":"exact"},{"name":"Joubert syndrome caused by mutation in B9D1","type":"exact"},{"name":"Joubert syndrome type 27","type":"exact"}],"termid":"MONDO:0014927","xrefs":{"Monarch":{"xref_id":"0014927"}}}


id: PBO:0018165
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial metallopeptidase, tRNA N6-threonyl-carbamoyl-adenosine (t6A), a modification protein Pgp1","termid":"PBO:0018165"}


id: PBO:0017663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SEA complex subunit, human WDR24 family, Sea2 (predicted)","termid":"PBO:0017663"}


id: MONDO:0011299
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any neurodegenerative disease with chorea in which the cause of the disease is a mutation in the PRNP gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"Huntington disease and related disorders","termid":"MONDO:0000167"},{"relation_name":"excluded_subClassOf","term_name":"movement disorder","termid":"MONDO:0005395"},{"relation_name":"is_a","term_name":"prion disease","termid":"MONDO:0005429"},{"relation_name":"is_a","term_name":"inherited neurodegenerative disorder","termid":"MONDO:0024237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"Huntington disease-like 1","secondary_identifiers":["MEDGEN:355137","OMIM:603218","DOID:0090103","MESH:C566398","UMLS:C1864112","Orphanet:157941","GARD:16985"],"synonyms":[{"name":"HDL1","type":"exact"},{"name":"HLN1","type":"exact"},{"name":"Huntington disease-like 1","type":"exact"},{"name":"Huntington disease-like type 1","type":"exact"},{"name":"Huntington's disease-like 1","type":"related"},{"name":"Huntington-like neurodegenerative disorder 1","type":"exact"},{"name":"Huntington-like neurodegenerative disorder, autosomal dominant","type":"related"},{"name":"PRNP neurodegenerative disease with chorea","type":"exact"},{"name":"autosomal dominant Huntington-like neurodegenerative disorder","type":"exact"},{"name":"early-onset prion disease with prominent psychiatric features","type":"exact"},{"name":"neurodegenerative disease with chorea caused by mutation in PRNP","type":"exact"},{"name":"prion disease, early-onset, with prominent psychiatric features","type":"related"}],"termid":"MONDO:0011299","xrefs":{"Monarch":{"xref_id":"0011299"}}}


id: PATO:0001082
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001082 damage value (obsolete PATO:0001082)","termid":"PATO:0001082"}


id: MONDO:0044937
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant epithelial neoplasm that arises from the rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas.","definition_xrefs":["NCIT:C9382"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rectal cancer","termid":"MONDO:0006519"},{"relation_name":"is_a","term_name":"colorectal carcinoma","termid":"MONDO:0024331"},{"relation_name":"is_a","term_name":"epithelial neoplasm of rectum","termid":"MONDO:0024476"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"rectal carcinoma","secondary_identifiers":["UMLS:C0007113","MEDGEN:40100"],"synonyms":[{"name":"cancer of rectum","type":"broad"},{"name":"cancer of the rectum","type":"broad"},{"name":"carcinoma of rectum","type":"exact"},{"name":"carcinoma of the rectum","type":"exact"},{"name":"rectal cancer","type":"broad"},{"name":"rectal carcinoma","type":"exact"},{"name":"rectum carcinoma","type":"exact"}],"termid":"MONDO:0044937","xrefs":{"Monarch":{"xref_id":"0044937"}}}


id: PBO:0036489
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRyPtophan requiring","termid":"PBO:0036489"}


id: PBO:0034559
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_kinetochore_morphology_during_vegetative_growth","termid":"PBO:0034559"}


id: MONDO:0007476
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial Dupuyren contracture is a rare, genetic, epidermal disease characterized by a, usually unilateral, progressive thickening and shortening of the palmar fascia, leading to permanent flexion contracture of the digits in several members of a family. It most commonly affects the fourth digit, followed by the fifth and then the third (first and second digits are usually spared).","definition_xrefs":["Orphanet:79142"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin neoplasm","termid":"MONDO:0002531"},{"relation_name":"is_a","term_name":"superficial Fibromatosis","termid":"MONDO:0016037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"familial Dupuytren contracture","secondary_identifiers":["MEDGEN:41672","OMIM:126900","SCTID:274142002","UMLS:C0013312"],"synonyms":[{"name":"Dupuytren contracture","type":"related"},{"name":"Dupuytren contracture 1","type":"related"},{"name":"plantar fibromas","type":"related"},{"name":"plantar fibromatosis, familial","type":"related"}],"termid":"MONDO:0007476","xrefs":{"Monarch":{"xref_id":"0007476"}}}


id: GO:0018082
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.","definition_xrefs":["RESID:AA0182"],"gene_count":0,"genotype_count":0,"name":"obsolete peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine (obsolete GO:0018082)","synonyms":[{"name":"peptidyl-(Z)-dehydrobutyrine anabolism from peptidyl-threonine","type":"exact"},{"name":"peptidyl-(Z)-dehydrobutyrine formation from peptidyl-threonine","type":"exact"},{"name":"peptidyl-(Z)-dehydrobutyrine synthesis from peptidyl-threonine","type":"exact"}],"termid":"GO:0018082"}


id: GO:0004876
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.","definition_xrefs":["ISBN:0781735149","GOC:signaling","GOC:add","GOC:mah","GOC:pg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"complement receptor activity","termid":"GO:0004875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"complement component C3a receptor activity","secondary_identifiers":["GO:0004943"],"synonyms":[{"name":"C3a anaphylatoxin receptor activity","type":"related"}],"termid":"GO:0004876"}


id: GO:0006139
data:
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id: PATO:0001723
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id: PR:O74885
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id: PBO:0015231
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id: GO:1990211
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id: PBO:0017065
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id: MONDO:0033364
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id: PBO:0041895
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id: GO:0019821
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id: GO:0102037
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id: GO:0106038
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id: GO:0010008
data:
  {"annotated_genes":["SJAG_00900","SJAG_04349","SJAG_07012","SJAG_01112","SJAG_04912","SJAG_03250","SJAG_00638","SJAG_04936","SJAG_04513","SJAG_01379","SJAG_00299","SJAG_04024","SJAG_00314","SJAG_01236","SJAG_00416","SJAG_02100","SJAG_00108","SJAG_01242","SJAG_04023","SJAG_05210","SJAG_01981","SJAG_00301","SJAG_03892","SJAG_03347","SJAG_02429","SJAG_04822","SJAG_02587","SJAG_03783","SJAG_04489","SJAG_05207","SJAG_03511"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[60668,72349,77837,79963,98442,101720,101732],"is_not":false,"summary":null,"term":"GO:0010008"},{"annotations":[90338],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010009"},{"annotations":[80078,95652,99471],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031901"},{"annotations":[71882,87880],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000813"},{"annotations":[70730,71888,78220],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000814"},{"annotations":[77539,70800,76157,70569,69811,75512],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000815"},{"annotations":[87881,99270,75783,97416,100834,78218,91764],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031902"},{"annotations":[118968,60368,62328],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032585"},{"annotations":[98624,75024],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0034424"}]},"cv_name":"cellular_component","definition":"The lipid bilayer surrounding an endosome.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic vesicle membrane","termid":"GO:0030659"},{"relation_name":"is_a","term_name":"bounding membrane of organelle","termid":"GO:0098588"},{"relation_name":"part_of","term_name":"endosome","termid":"GO:0005768"}],"gene_count":31,"genes_by_uniquename":{"SJAG_00108":null,"SJAG_00299":null,"SJAG_00301":null,"SJAG_00314":null,"SJAG_00416":null,"SJAG_00638":null,"SJAG_00900":null,"SJAG_01112":null,"SJAG_01236":null,"SJAG_01242":null,"SJAG_01379":null,"SJAG_01981":null,"SJAG_02100":null,"SJAG_02429":null,"SJAG_02587":null,"SJAG_03250":null,"SJAG_03347":null,"SJAG_03511":null,"SJAG_03783":null,"SJAG_03892":null,"SJAG_04023":null,"SJAG_04024":null,"SJAG_04349":null,"SJAG_04489":null,"SJAG_04513":null,"SJAG_04822":null,"SJAG_04912":null,"SJAG_04936":null,"SJAG_05207":null,"SJAG_05210":null,"SJAG_07012":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005768"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0005768","GO:0005575","GO:0031410","GO:0005737"],"is_obsolete":false,"name":"endosome membrane","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000044":null,"GO_REF:0000104":null,"GO_REF:0000107":null,"PMID:32109380":null},"secondary_identifiers":["NIF_Subcellular:sao978443756"],"synonyms":[{"name":"endosomal membrane","type":"exact"}],"termid":"GO:0010008","terms_by_termid":{"GO:0000813":null,"GO:0000814":null,"GO:0000815":null,"GO:0010008":null,"GO:0010009":null,"GO:0031901":null,"GO:0031902":null,"GO:0032585":null,"GO:0034424":null}}


id: MONDO:0032642
data:
  {"annotated_genes":["SJAG_03631","SJAG_01790"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86031,86032],"is_not":false,"summary":null,"term":"MONDO:0032642"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01790":null,"SJAG_03631":null},"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:18001","MEDGEN:1648372","UMLS:C4748872","OMIM:618265","Orphanet:565858"],"synonyms":[{"name":"ACCIID","type":"related"},{"name":"ARTHROGRYPOSIS, CLEFT PALATE, CRANIOSYNOSTOSIS, AND IMPAIRED INTELLECTUAL DEVELOPMENT","type":"related"}],"termid":"MONDO:0032642","terms_by_termid":{"MONDO:0032642":null},"xrefs":{"Monarch":{"xref_id":"0032642"}}}


id: PATO:0001811
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A relaxation which is relatively high.","definition_xrefs":["PATOC:GVG"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001811 increased relaxation (obsolete PATO:0001811)","synonyms":[{"name":"high relaxation","type":"exact"}],"termid":"PATO:0001811"}


id: GO:0140631
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).","definition_xrefs":["PMID:33495566"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme inhibitor activity","termid":"GO:0004857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0004857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0030234","GO:0004857","GO:0140678","GO:0003674","GO:0098772"],"is_obsolete":false,"name":"aldehyde dehydrogenase (NAD+) inhibitor activity","termid":"GO:0140631"}


id: FYPO:0002059
data:
  {"alleles_by_uniquename":{"SJAG_02409:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02409","name":"stc1delta","uniquename":"SJAG_02409:allele-1"},"SJAG_02594:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02594","name":"arb1delta","uniquename":"SJAG_02594:allele-1"},"SJAG_02621:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02621","name":"ago1delta","uniquename":"SJAG_02621:allele-1"},"SJAG_03118:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03118","name":"leo1delta","uniquename":"SJAG_03118:allele-1"},"SJAG_03356:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03356","name":"rdp1delta","uniquename":"SJAG_03356:allele-1"},"SJAG_03689:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03689","name":"dcr1delta","uniquename":"SJAG_03689:allele-1"},"SJAG_03916:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03916","name":"chp1delta","uniquename":"SJAG_03916:allele-1"},"SJAG_04061:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04061","name":"arb2delta","uniquename":"SJAG_04061:allele-1"},"SJAG_04574:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04574","name":"clr4delta","uniquename":"SJAG_04574:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"multi_locus_phenotype":[{"annotations":[119220],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0002061"}],"single_locus_phenotype":[{"annotations":[119205,119209,119203,119208,119219,119204,119206,119207],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0002061"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which none of the cells in the population are viable.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population viability","termid":"FYPO:0002057"}],"gene_count":9,"genes_by_uniquename":{"SJAG_02409":null,"SJAG_02594":null,"SJAG_02621":null,"SJAG_03118":null,"SJAG_03356":null,"SJAG_03689":null,"SJAG_03916":null,"SJAG_04061":null,"SJAG_04574":null},"genotype_count":9,"genotypes_by_uniquename":{"ago1delta":{"display_name":"ago1delta","display_uniquename":"ago1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02621:allele-1","expression":"Null"}]}]},"arb1delta":{"display_name":"arb1delta","display_uniquename":"arb1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02594:allele-1","expression":"Null"}]}]},"arb2delta":{"display_name":"arb2delta","display_uniquename":"arb2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04061:allele-1","expression":"Null"}]}]},"chp1delta":{"display_name":"chp1delta","display_uniquename":"chp1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03916:allele-1","expression":"Null"}]}]},"clr4delta":{"display_name":"clr4delta","display_uniquename":"clr4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04574:allele-1","expression":"Null"}]}]},"clr4delta__leo1delta":{"display_name":"clr4delta leo1delta","display_uniquename":"clr4delta__leo1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04574:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_03118:allele-1","expression":"Null"}]}]},"dcr1delta":{"display_name":"dcr1delta","display_uniquename":"dcr1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03689:allele-1","expression":"Null"}]}]},"rdp1delta":{"display_name":"rdp1delta","display_uniquename":"rdp1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03356:allele-1","expression":"Null"}]}]},"stc1delta":{"display_name":"stc1delta","display_uniquename":"stc1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02409:allele-1","expression":"Null"}]}]}},"in_subsets":["fypo_slim"],"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002057"],"is_obsolete":false,"multi_locus_annotated_genes":["SJAG_04574","SJAG_03118"],"name":"inviable cell population","references_by_uniquename":{"PMID:35226668":null},"single_locus_annotated_genes":["SJAG_02621","SJAG_03356","SJAG_03689","SJAG_04574","SJAG_03916","SJAG_02594","SJAG_02409","SJAG_04061"],"single_locus_genotype_uniquenames":["stc1delta","arb2delta","ago1delta","arb1delta","dcr1delta","clr4delta","rdp1delta","chp1delta"],"synonyms":[{"name":"essential","type":"related"},{"name":"lethal in cell population","type":"exact"}],"termid":"FYPO:0002059","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000162":null,"FYPO:0002061":null}}


id: GO:0033566
data:
  {"annotated_genes":["SJAG_01756"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[116931],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990735"}]},"cv_name":"biological_process","definition":"Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex localization","termid":"GO:0031503"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01756":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"gamma-tubulin complex localization","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"establishment and maintenance of gamma-tubulin complex localization","type":"exact"},{"name":"gamma-tubulin complex localisation","type":"exact"}],"termid":"GO:0033566","terms_by_termid":{"GO:1990735":null}}


id: GO:1905548
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of subtelomeric heterochromatin assembly.","definition_xrefs":["GOC:BHF","GOC:TermGenie","GOC:BHF_telomere","PMID:25819580","GOC:nc","GO_REF:0000058"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of subtelomeric heterochromatin assembly (obsolete GO:1905548)","synonyms":[{"name":"down regulation of telomeric heterochromatin assembly","type":"related"},{"name":"down regulation of telomeric heterochromatin formation","type":"related"},{"name":"down-regulation of telomeric heterochromatin assembly","type":"related"},{"name":"down-regulation of telomeric heterochromatin formation","type":"related"},{"name":"downregulation of telomeric heterochromatin assembly","type":"related"},{"name":"downregulation of telomeric heterochromatin formation","type":"related"},{"name":"inhibition of telomeric heterochromatin assembly","type":"narrow"},{"name":"inhibition of telomeric heterochromatin formation","type":"narrow"},{"name":"negative regulation of telomeric heterochromatin assembly","type":"related"},{"name":"negative regulation of telomeric heterochromatin formation","type":"related"}],"termid":"GO:1905548"}


id: MONDO:0001202
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"prostate disorder","termid":"MONDO:0003105"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostatic cyst","secondary_identifiers":["MEDGEN:731233","DOID:11133","UMLS:C1443972","ICD10CM:N42.83","ICD9:599.89","SCTID:409658007","ICD9:600.3"],"synonyms":[{"name":"cyst of prostate","type":"exact"}],"termid":"MONDO:0001202","xrefs":{"Monarch":{"xref_id":"0001202"}}}


id: MONDO:0008588
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary geniospasm is a movement disorder characterized by episodes of involuntary tremor of the chin and lower lip.","definition_xrefs":["Orphanet:53372"],"direct_ancestors":[{"relation_name":"is_a","term_name":"movement disorder","termid":"MONDO:0005395"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hereditary geniospasm","secondary_identifiers":["SCTID:718103001","OMIM:190100","MEDGEN:348757","MESH:C537682","UMLS:C1860972","GARD:9501"],"synonyms":[{"name":"GSM 1","type":"related"},{"name":"GSM1","type":"related"},{"name":"familial trembling of the chin","type":"exact"},{"name":"geniospasm","type":"related"},{"name":"geniospasm 1","type":"related"},{"name":"hereditary chin myoclonus","type":"exact"},{"name":"hereditary chin tremor/myoclonus","type":"related"},{"name":"hereditary chin-trembling","type":"exact"},{"name":"trembling Chin","type":"related"}],"termid":"MONDO:0008588","xrefs":{"Monarch":{"xref_id":"0008588"}}}


id: PR:O59683
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A translation initiation factor IF-2, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02412","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation initiation factor IF-2, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1271.15c","secondary_identifiers":["UniProtKB:O59683"],"synonyms":[{"name":"IF-2(Mt) (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"IF-2Mt (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"IF2(mt) (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-MTIF2","type":"exact"}],"termid":"PR:O59683"}


id: MONDO:0009551
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"magnesium, elevated red cell","secondary_identifiers":["MEDGEN:343360","OMIM:248260","UMLS:C1855464"],"synonyms":[{"name":"magnesium, elevated red cell","type":"exact"}],"termid":"MONDO:0009551","xrefs":{"Monarch":{"xref_id":"0009551"}}}


id: PBO:0060742
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase complex assembly factor 7","termid":"PBO:0060742"}


id: PBO:0044009
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"casein kappa","termid":"PBO:0044009"}


id: GO:0120058
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.","definition_xrefs":["GOC:sl","PMID:15890336"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of digestive system process","termid":"GO:0060456"},{"relation_name":"is_a","term_name":"regulation of small intestinal transit","termid":"GO:0120057"},{"relation_name":"positively_regulates","term_name":"small intestinal transit","termid":"GO:0120055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of small intestinal transit","synonyms":[{"name":"positive regulation of small bowel transit","type":"exact"},{"name":"positive regulation of small intestine transit","type":"exact"}],"termid":"GO:0120058"}


id: PBO:0067584
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 743, pseudogene","termid":"PBO:0067584"}


id: PBO:0047034
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 98 member B","termid":"PBO:0047034"}


id: GO:0003858
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + H+ + NADH.","definition_xrefs":["EC:1.1.1.30","RHEA:20521"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"3-hydroxybutyrate dehydrogenase activity","secondary_identifiers":["Reactome:R-HSA-73920","KEGG_REACTION:R01361","Reactome:R-HSA-73912","MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN","Reactome:R-HSA-5696457"],"synonyms":[{"name":"D-beta-hydroxybutyrate dehydrogenase activity","type":"related"}],"termid":"GO:0003858"}


id: FYPO:0000699
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which DNA-7-methylguanine glycosylase activity is absent.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished catalytic activity","termid":"FYPO:0000664"},{"relation_name":"is_a","term_name":"abnormal DNA-7-methylguanine glycosylase activity","termid":"FYPO:0000697"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000661","FYPO:0000654","FYPO:0000652","FYPO:0000707"],"is_obsolete":false,"name":"abolished DNA-7-methylguanine glycosylase activity","synonyms":[{"name":"DNA-7-methylguanine glycosylase activity abolished","type":"exact"}],"termid":"FYPO:0000699"}


id: PR:O14102
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A splicing factor 3B subunit 4 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO01246","PANTHER:PTHR24011:SF51"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spliceosome-associated protein 49 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC31G5.01","secondary_identifiers":["UniProtKB:O14102"],"synonyms":[{"name":"Spom972h-SF3B4","type":"exact"}],"termid":"PR:O14102"}


id: SO:0000557
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"3'-most region of a precursor transcript that is clipped off during processing.","direct_ancestors":[{"relation_name":"is_a","term_name":"clip","termid":"SO:0000303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"three_prime_clip","synonyms":[{"name":"3'-clip","type":"exact"},{"name":"three prime clip","type":"exact"}],"termid":"SO:0000557"}


id: MONDO:0014183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"myopia","termid":"MONDO:0001384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"myopia 23, autosomal recessive","secondary_identifiers":["GARD:18198","OMIM:615431","MEDGEN:815812","UMLS:C3809482"],"synonyms":[{"name":"MYP23","type":"related"},{"name":"myopia 23, autosomal recessive","type":"exact"}],"termid":"MONDO:0014183","xrefs":{"Monarch":{"xref_id":"0014183"}}}


id: PBO:0061455
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor subfamily 6 group A member 1","termid":"PBO:0061455"}


id: GO:0031459
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).","definition_xrefs":["RHEA:32783","GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino-acid betaine transmembrane transporter activity","termid":"GO:0015199"},{"relation_name":"is_a","term_name":"ABC-type quaternary ammonium compound transporting activity","termid":"GO:0015418"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"ABC-type glycine betaine transporter activity","secondary_identifiers":["MetaCyc:TRANS-RXN-283"],"synonyms":[{"name":"ATP-dependent glycine betaine transporter activity","type":"exact"},{"name":"ATPase-coupled glycine betaine transporter activity","type":"related"},{"name":"N-trimethylglycine-transporting ATPase activity","type":"exact"},{"name":"glycine betaine ABC transporter","type":"narrow"},{"name":"glycine betaine-transporting ATPase activity","type":"related"}],"termid":"GO:0031459"}


id: GO:2000965
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of catabolic process","termid":"GO:0009896"},{"relation_name":"is_a","term_name":"positive regulation of cellooligosaccharide metabolic process","termid":"GO:2000962"},{"relation_name":"is_a","term_name":"regulation of cellooligosaccharide catabolic process","termid":"GO:2000963"},{"relation_name":"positively_regulates","term_name":"cellooligosaccharide catabolic process","termid":"GO:2000903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"positively_regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"positive regulation of cellooligosaccharide catabolic process","synonyms":[{"name":"positive regulation of cellooligosaccharide catabolism","type":"exact"}],"termid":"GO:2000965"}


id: MONDO:0044786
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A low-grade malignant neoplasm that arises from the exocrine pancreas. It is characterized by the presence of uniform cells that form solid and pseudopapillary patterns, cystic changes, and hemorrhage. Perineural invasion, vascular invasion, and invasion into surrounding tissues may be present. It usually presents as an encapsulated, solitary, and lobulated pancreatic mass. It is usually found incidentally during physical examination or it may present with abdominal discomfort and pain. It occurs predominantly in young women. Complete removal of the tumor is curative in the majority of cases.","definition_xrefs":["NCIT:C37212"],"direct_ancestors":[{"relation_name":"is_a","term_name":"malignant exocrine pancreas neoplasm","termid":"MONDO:0002116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"solid pseudopapillary neoplasm of the pancreas","secondary_identifiers":["MEDGEN:234800","ONCOTREE:SPN","UMLS:C1336030"],"synonyms":[{"name":"Frantz tumor","type":"exact"},{"name":"Frantz tumour","type":"exact"},{"name":"solid pseudopapillary neoplasm of the pancreas","type":"exact"},{"name":"solid pseudopapillary tumor of the pancreas","type":"exact"},{"name":"solid pseudopapillary tumour of the pancreas","type":"exact"}],"termid":"MONDO:0044786","xrefs":{"Monarch":{"xref_id":"0044786"}}}


id: PBO:0044298
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome b5 type A","termid":"PBO:0044298"}


id: GO:0071827
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multicellular organismal process","termid":"GO:0032501"},{"relation_name":"is_a","term_name":"protein-lipid complex organization","termid":"GO:0071825"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"plasma lipoprotein particle organization","secondary_identifiers":["Reactome:R-HSA-174824"],"synonyms":[{"name":"plasma lipoprotein particle organisation","type":"exact"}],"termid":"GO:0071827"}


id: PBO:0074484
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SET and MYND domain containing 3","termid":"PBO:0074484"}


id: PBO:0065160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostate cancer associated non-coding RNA 1","termid":"PBO:0065160"}


id: PBO:0050746
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family E (Hsp10) member 1 pseudogene 8","termid":"PBO:0050746"}


id: GO:1903503
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex which is capable of ATPase inhibitor activity.","definition_xrefs":["GOC:TermGenie","GOC:bhm","GO_REF:0000088","PMID:16170325"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"ATPase inhibitor complex","termid":"GO:1903503"}


id: MONDO:0004370
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A meningioma that affects the sphenocavernous region.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skull base meningioma","termid":"MONDO:0002998"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sphenocavernous meningioma","secondary_identifiers":["UMLS:C1336036","MEDGEN:234801","NCIT:C5313","DOID:7820"],"termid":"MONDO:0004370","xrefs":{"Monarch":{"xref_id":"0004370"}}}


id: MONDO:0014942
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the GABRB1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"undetermined early-onset epileptic encephalopathy","termid":"MONDO:0018614"},{"relation_name":"is_a","term_name":"neonatal-onset developmental and epileptic encephalopathy","termid":"MONDO:0100455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0004736","MONDO:0005027","MONDO:0005066"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 45","secondary_identifiers":["MEDGEN:934658","UMLS:C4310691","OMIM:617153","GARD:16203","DOID:0080428"],"synonyms":[{"name":"DEE45","type":"exact"},{"name":"EIEE45","type":"exact"},{"name":"GABRB1 early infantile epileptic encephalopathy","type":"exact"},{"name":"developmental and epileptic encephalopathy 45","type":"exact"},{"name":"early infantile epileptic encephalopathy caused by mutation in GABRB1","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 45","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 45; EIEE45","type":"exact"},{"name":"epileptic encephalopathy, early infantile, type 45","type":"exact"}],"termid":"MONDO:0014942","xrefs":{"Monarch":{"xref_id":"0014942"}}}


id: GO:0006878
data:
  {"annotated_genes":["SJAG_04403","SJAG_02399","SJAG_00802","SJAG_01694","SJAG_00668"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[74764,77834,92901,99916,107605],"is_not":false,"summary":null,"term":"GO:0006878"}]},"cv_name":"biological_process","definition":"A homeostatic process involved in the maintenance of a steady state level of copper ions within a cell.","definition_xrefs":["GOC:mah","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular monoatomic cation homeostasis","termid":"GO:0030003"},{"relation_name":"is_a","term_name":"copper ion homeostasis","termid":"GO:0055070"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00668":null,"SJAG_00802":null,"SJAG_01694":null,"SJAG_02399":null,"SJAG_04403":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098771"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0098771"],"is_obsolete":false,"name":"intracellular copper ion homeostasis","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"cellular copper ion homeostasis","type":"exact"},{"name":"copper homeostasis","type":"broad"}],"termid":"GO:0006878","terms_by_termid":{"GO:0006878":null}}


id: MONDO:0975808
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital myopathy","termid":"MONDO:0019952"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"congenital myopathy 25","secondary_identifiers":["OMIM:620964"],"termid":"MONDO:0975808","xrefs":{"Monarch":{"xref_id":"0975808"}}}


id: PBO:0038727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin gamma 1 pseudogene 22","termid":"PBO:0038727"}


id: GO:0043772
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate.","definition_xrefs":["PMID:17308305"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, transferring groups other than amino-acyl groups","termid":"GO:0016747"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016746"],"is_obsolete":false,"name":"acyl-phosphate glycerol-3-phosphate acyltransferase activity","synonyms":[{"name":"acyl-phosphate:glycerol-3-phosphate acyltransferase activity","type":"exact"},{"name":"acylphosphate glycerol-3-phosphate acyltransferase activity","type":"exact"},{"name":"acylphosphate:glycerol-3-phosphate acyltransferase activity","type":"exact"}],"termid":"GO:0043772"}


id: PBO:0004456
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"19S proteasome regulatory subunit Rpn2 (predicted)","termid":"PBO:0004456"}


id: PBO:0084031
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Golgi membrane protein of unknown function; interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting; conserved from yeast to human","termid":"PBO:0084031"}


id: PBO:0076747
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tectonic family member 2","termid":"PBO:0076747"}


id: PBO:0091597
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"was previously incorrectly annotated as pex22","termid":"PBO:0091597"}


id: FYPO:0004086
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which centromere clustering is abnormal during one or both meiotic nuclear divisions. Centromeres are normally located in one or two clusters away from the spindle pole body during meiosis.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiotic chromosome segregation","termid":"FYPO:0000151"},{"relation_name":"is_a","term_name":"abnormal protein localization during meiotic cell cycle","termid":"FYPO:0004094"},{"relation_name":"is_a","term_name":"abnormal meiotic chromosome organization","termid":"FYPO:0006759"},{"relation_name":"is_a","term_name":"abnormal microtubule-based movement","termid":"FYPO:0007163"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"part_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000641","FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0000631"],"is_obsolete":false,"name":"abnormal meiotic centromere clustering","synonyms":[{"name":"abnormal centromere clustering during meiosis","type":"exact"},{"name":"abnormal chromosome retrieval during meiosis","type":"related"},{"name":"abnormal kinetochore retrieval during meiosis","type":"related"},{"name":"increased unclustered centromeres during meiosis","type":"related"}],"termid":"FYPO:0004086"}


id: PR:Q9C1X0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A mitogen-activated protein kinase organizer 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02622","PANTHER:PTHR22842:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized WD repeat-containing protein C713.05 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC713.05","secondary_identifiers":["UniProtKB:Q9C1X0"],"synonyms":[{"name":"Spom972h-WDR83","type":"exact"}],"termid":"PR:Q9C1X0"}


id: PBO:0038387
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_active_ingredient","termid":"PBO:0038387"}


id: PBO:0003898
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudogene, DUF1773 family","termid":"PBO:0003898"}


id: RO:0003306
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the frequency of the condition in a population.","direct_ancestors":[{"relation_name":"is_a","term_name":"contributes_to_condition","termid":"RO:0003304"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"contributes_to_frequency_of_condition","termid":"RO:0003306"}


id: GO:0140785
data:
  {"annotated_genes":["SJAG_03405"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[112607],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140786"}]},"cv_name":"molecular_function","definition":"Binding to and responding, e.g. by conformational change, to changes in the cellular level of an amino acid.","definition_xrefs":["GOC:pg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molecular sensor activity","termid":"GO:0140299"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03405":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0140299"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0098772","GO:0140299","GO:0003674"],"is_obsolete":false,"name":"amino acid sensor activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"amino acid sensing activity","type":"exact"}],"termid":"GO:0140785","terms_by_termid":{"GO:0140786":null}}


id: GO:0018887
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid.","definition_xrefs":["PMID:9603860"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfur compound metabolic process","termid":"GO:0006790"},{"relation_name":"is_a","term_name":"monocarboxylic acid metabolic process","termid":"GO:0032787"},{"relation_name":"is_a","term_name":"benzene-containing compound metabolic process","termid":"GO:0042537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006790","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"4-carboxy-4'-sulfoazobenzene metabolic process","secondary_identifiers":["UM-BBD_pathwayID:csab"],"synonyms":[{"name":"4-carboxy-4'-sulfoazobenzene metabolism","type":"exact"},{"name":"4-carboxy-4'-sulphoazobenzene metabolic process","type":"exact"},{"name":"4-carboxy-4'-sulphoazobenzene metabolism","type":"exact"}],"termid":"GO:0018887"}


id: PR:O94241
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An actin-related protein 6 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11937:SF21","OMA:SCHPO04597","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin-like protein arp6 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC550.12","secondary_identifiers":["UniProtKB:O94241"],"synonyms":[{"name":"Spom972h-ACTR6","type":"exact"}],"termid":"PR:O94241"}


id: PBO:0086264
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that regulates ubiquitination of Rsp5p; has a WW domain consensus motif of PPPSY (residues 131-135) that mediates binding of Rsp5p to Ubp2p; contains an UBA domain; relative distribution to the nucleus increases upon DNA replication stress","termid":"PBO:0086264"}


id: MONDO:0030693
data:
  {"annotated_genes":["SJAG_00198"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86907],"is_not":false,"summary":null,"term":"MONDO:0030693"}]},"cv_name":"mondo","definition":"An autosomal recessive disorder characterized by onset of recurrent, usually viral, respiratory infections in infancy or early childhood. Other infections, including gastrointestinal and urinary tract infections, may also occur. Laboratory studies show hypogammaglobulinemia, lymphopenia with increased gamma/delta T cells, and erythrocyte macrocytosis. The disorder results from defective cellular DNA repair.","definition_xrefs":["OMIM:619774"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00198":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 96","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1810465","UMLS:C5676930"],"synonyms":[{"name":"IMD96","type":"exact"},{"name":"immunodeficiency 96","type":"exact"},{"name":"immunodeficiency, autosomal recessive due to LIG1 deficiency","type":"exact"}],"termid":"MONDO:0030693","terms_by_termid":{"MONDO:0030693":null},"xrefs":{"Monarch":{"xref_id":"0030693"}}}


id: GO:0034653
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diterpenoid catabolic process","termid":"GO:0016103"},{"relation_name":"is_a","term_name":"fat-soluble vitamin catabolic process","termid":"GO:0042363"},{"relation_name":"is_a","term_name":"retinoic acid metabolic process","termid":"GO:0042573"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0006766"}],"interesting_parent_ids":["GO:0044248","GO:0008150","GO:0006629","GO:0006766","GO:0044281"],"is_obsolete":false,"name":"retinoic acid catabolic process","synonyms":[{"name":"retinoic acid breakdown","type":"exact"},{"name":"retinoic acid catabolism","type":"exact"},{"name":"retinoic acid degradation","type":"exact"},{"name":"vitamin A1 acid catabolic process","type":"exact"}],"termid":"GO:0034653"}


id: MONDO:0012359
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of combined T and B cell immunodeficiency (CID) characterized by severe and persistent cytomegalovirus (CMV) infection and autoimmune cytopenia.","definition_xrefs":["Orphanet:231154"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"non-SCID combined immunodeficiency","termid":"MONDO:0018814"},{"relation_name":"is_a","term_name":"T-B- severe combined immunodeficiency","termid":"MONDO:0017855"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"combined immunodeficiency due to partial RAG1 deficiency","secondary_identifiers":["UMLS:C1835931","GARD:13712","OMIM:609889","MEDGEN:372161","MESH:C563691","SCTID:725290000"],"synonyms":[{"name":"CID due to partial RAG1 deficiency","type":"exact"},{"name":"CID with expansion of gamma delta T cells","type":"exact"},{"name":"alpha/beta T-cell lymphopenia with gamma/DELTA T-cell expansion, severe CYTOMEGALOVIRUS infection, and autoimmunity","type":"related"},{"name":"combined immunodeficiency with expansion of gamma delta T cells","type":"exact"}],"termid":"MONDO:0012359","xrefs":{"Monarch":{"xref_id":"0012359"}}}


id: PATO:0001506
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in a bearer by virtue of the bearer's separation of normally joined parts, such as the separation of adjacent bones without fracture or of certain abdominal muscles during pregnancy.","definition_xrefs":["answers.com:answers.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"separated from","termid":"PATO:0001505"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diastatic","termid":"PATO:0001506"}


id: GO:1905701
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:15198509","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transmembrane transport","termid":"GO:0034764"},{"relation_name":"is_a","term_name":"positive regulation of response to stimulus","termid":"GO:0048584"},{"relation_name":"is_a","term_name":"regulation of xenobiotic detoxification by transmembrane export across the plasma membrane","termid":"GO:1905699"},{"relation_name":"positively_regulates","term_name":"xenobiotic detoxification by transmembrane export across the plasma membrane","termid":"GO:1990961"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane","synonyms":[{"name":"activation of drug transmembrane export","type":"narrow"},{"name":"positive regulation of drug transmembrane export","type":"narrow"},{"name":"positive regulation of xenobiotic transmembrane export","type":"narrow"},{"name":"up regulation of drug transmembrane export","type":"narrow"},{"name":"up-regulation of drug transmembrane export","type":"narrow"},{"name":"upregulation of drug transmembrane export","type":"narrow"}],"termid":"GO:1905701"}


id: PBO:0046697
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ETS1 antisense RNA 1","termid":"PBO:0046697"}


id: PR:P0CAN8
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- nxt1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P0CAN8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NTF2-related export protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB1A10.03","synonyms":[{"name":"Spom972h-nxt1","type":"exact"},{"name":"p15 (Schizosaccharomyces pombe 972h-)","type":"broad"}],"termid":"PR:P0CAN8"}


id: PBO:0067367
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 468, pseudogene","termid":"PBO:0067367"}


id: MONDO:0033047
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Perrault syndrome","termid":"MONDO:0017312"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005066","MONDO:0004069","MONDO:0005047"],"is_obsolete":false,"name":"Perrault syndrome 6","secondary_identifiers":["DOID:0080256","OMIM:617565","UMLS:C4479656","MEDGEN:1391447","GARD:16237"],"synonyms":[{"name":"PRLTS6","type":"related"},{"name":"Perrault syndrome 6","type":"exact"}],"termid":"MONDO:0033047","xrefs":{"Monarch":{"xref_id":"0033047"}}}


id: GO:0050626
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.","definition_xrefs":["EC:1.7.2.3","MetaCyc:1.7.2.3-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor","termid":"GO:0016662"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"trimethylamine-N-oxide reductase (cytochrome c) activity","secondary_identifiers":["RHEA:24236","Wikipedia:Trimethylamine_N-oxide_reductase"],"synonyms":[{"name":"TMAO reductase activity","type":"related"},{"name":"TOR activity","type":"related"},{"name":"trimethylamine:cytochrome c oxidoreductase activity","type":"related"}],"termid":"GO:0050626"}


id: PBO:0043569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type VI alpha 6 chain","termid":"PBO:0043569"}


id: GO:1901470
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of catabolic process","termid":"GO:0009895"},{"relation_name":"is_a","term_name":"regulation of syringal lignin catabolic process","termid":"GO:1901469"},{"relation_name":"negatively_regulates","term_name":"syringal lignin catabolic process","termid":"GO:1901065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"negative regulation of syringal lignin catabolic process","synonyms":[{"name":"down regulation of S-lignin catabolic process","type":"exact"},{"name":"down regulation of syringal lignin breakdown","type":"exact"},{"name":"down regulation of syringal lignin catabolic process","type":"exact"},{"name":"down regulation of syringal lignin catabolism","type":"exact"},{"name":"down regulation of syringal lignin degradation","type":"exact"},{"name":"down-regulation of S-lignin catabolic process","type":"exact"},{"name":"down-regulation of syringal lignin breakdown","type":"exact"},{"name":"down-regulation of syringal lignin catabolic process","type":"exact"},{"name":"down-regulation of syringal lignin catabolism","type":"exact"},{"name":"down-regulation of syringal lignin degradation","type":"exact"},{"name":"downregulation of S-lignin catabolic process","type":"exact"},{"name":"downregulation of syringal lignin breakdown","type":"exact"},{"name":"downregulation of syringal lignin catabolic process","type":"exact"},{"name":"downregulation of syringal lignin catabolism","type":"exact"},{"name":"downregulation of syringal lignin degradation","type":"exact"},{"name":"inhibition of S-lignin catabolic process","type":"exact"},{"name":"inhibition of syringal lignin breakdown","type":"exact"},{"name":"inhibition of syringal lignin catabolic process","type":"narrow"},{"name":"inhibition of syringal lignin catabolism","type":"exact"},{"name":"inhibition of syringal lignin degradation","type":"exact"},{"name":"negative regulation of S-lignin catabolic process","type":"exact"},{"name":"negative regulation of syringal lignin breakdown","type":"exact"},{"name":"negative regulation of syringal lignin catabolism","type":"exact"},{"name":"negative regulation of syringal lignin degradation","type":"exact"}],"termid":"GO:1901470"}


id: PBO:0063015
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAGE family member 3","termid":"PBO:0063015"}


id: MONDO:0011660
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the MYO6 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 22","secondary_identifiers":["MESH:C538197","DOID:0110552","GARD:9167","MEDGEN:419894","OMIM:606346","UMLS:C2931767"],"synonyms":[{"name":"DFNA 22","type":"related"},{"name":"DFNA22","type":"narrow"},{"name":"MYO6 autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"autosomal dominant deafness 22","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 22","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in MYO6","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 22","type":"narrow"},{"name":"deafness, autosomal dominant 22","type":"narrow"},{"name":"deafness, autosomal dominant 22, with hypertrophic cardiomyopathy","type":"narrow"},{"name":"deafness, autosomal dominant nonsyndromic sensorineural 22","type":"narrow"},{"name":"deafness, autosomal dominant type 22","type":"narrow"}],"termid":"MONDO:0011660","xrefs":{"Monarch":{"xref_id":"0011660"}}}


id: PBO:0070232
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 170 pseudogene","termid":"PBO:0070232"}


id: MONDO:0013183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any congenital stationary night blindness in which the cause of the disease is a mutation in the TRPM1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital stationary night blindness","termid":"MONDO:0016293"},{"relation_name":"is_a","term_name":"TRPM1-related retinopathy","termid":"MONDO:0800402"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"congenital stationary night blindness 1C","secondary_identifiers":["GARD:15631","DOID:0110867","MESH:C567704","OMIM:613216","MEDGEN:416373","UMLS:C2750747"],"synonyms":[{"name":"CSNB, complete, autosomal recessive","type":"related"},{"name":"CSNB1C","type":"exact"},{"name":"TRPM1 congenital stationary night blindness","type":"exact"},{"name":"congenital stationary night blindness 1C","type":"exact"},{"name":"congenital stationary night blindness 1C autosomal recessive","type":"exact"},{"name":"congenital stationary night blindness caused by mutation in TRPM1","type":"exact"},{"name":"congenital stationary night blindness type 1C","type":"exact"},{"name":"night blindness, congenital stationary (complete), 1C, autosomal recessive","type":"exact"},{"name":"night blindness, congenital stationary, type 1C","type":"related"}],"termid":"MONDO:0013183","xrefs":{"Monarch":{"xref_id":"0013183"}}}


id: GO:0016277
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine.","definition_xrefs":["PMID:6177833"],"gene_count":0,"genotype_count":0,"name":"obsolete [myelin basic protein]-arginine N-methyltransferase activity (obsolete GO:0016277)","termid":"GO:0016277"}


id: PBO:0074817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 17","termid":"PBO:0074817"}


id: GO:1900546
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of phenotypic switching.","definition_xrefs":["GOC:TermGenie","GOC:di"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter (obsolete GO:1900546)","synonyms":[{"name":"activation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"activation of phenotypic switching by regulation of transcription from RNA polymerase II promoter","type":"narrow"},{"name":"positive regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"up regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"up regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"up-regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"up-regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"upregulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter","type":"related"},{"name":"upregulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:1900546"}


id: GO:2000658
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.","definition_xrefs":["GOC:BHF"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of apolipoprotein binding (obsolete GO:2000658)","termid":"GO:2000658"}


id: PBO:0040659
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Bardet-Biedl syndrome 4","termid":"PBO:0040659"}


id: MONDO:0015396
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital laryngeal cyst is a rare larynx anomaly characterized by a cyst involving the larynx or supraglottis locations, such as the epiglottis and vallecula. Timing and severity of presentation depend on the size of the cyst and its proximity to the glottis and range from severe prenatal airway obstruction leading to polyhydramnios and pulmonary hypoplasia to postnatal inspiratory stridor associated with muffled cry, hoarseness and cyanotic episodes, and to feeding difficulties and failure to thrive. It can be associated with laryngomalacia.","definition_xrefs":["Orphanet:141124"],"direct_ancestors":[{"relation_name":"is_a","term_name":"laryngeal disorder","termid":"MONDO:0004382"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital laryngeal cyst","secondary_identifiers":["UMLS:C0339880","icd11.foundation:591042640","MEDGEN:451040","SCTID:765763007","GARD:19953"],"termid":"MONDO:0015396","xrefs":{"Monarch":{"xref_id":"0015396"}}}


id: GO:0098933
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a symbiont effects a change that impairs the structure or function of the host cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated disruption of host cellular anatomical structure","termid":"GO:0052008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated disruption of host cell envelope","synonyms":[{"name":"disruption by symbiont of host cell envelope","type":"exact"}],"termid":"GO:0098933"}


id: GO:0097475
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.","definition_xrefs":["PMID:20711475","GOC:yaf","CL:0000100"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron migration","termid":"GO:0001764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"motor neuron migration","termid":"GO:0097475"}


id: GO:0004940
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors.","definition_xrefs":["GOC:mah","IUPHAR_GPCR:1274"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-adrenergic receptor activity","termid":"GO:0004939"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"beta1-adrenergic receptor activity","synonyms":[{"name":"beta1 adrenoceptor","type":"exact"}],"termid":"GO:0004940"}


id: MONDO:0015417
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"facial cleft","termid":"MONDO:0015411"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tessier number 6 facial cleft","secondary_identifiers":["MEDGEN:609365","Orphanet:141265","GARD:19969","icd11.foundation:1934815559","UMLS:C0432120"],"termid":"MONDO:0015417","xrefs":{"Monarch":{"xref_id":"0015417"}}}


id: GO:0007589
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The controlled release of a fluid by a cell or tissue in an animal.","definition_xrefs":["GOC:mah","GOC:tb","GOC:dph","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secretion","termid":"GO:0046903"},{"relation_name":"is_a","term_name":"regulation of body fluid levels","termid":"GO:0050878"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"body fluid secretion","termid":"GO:0007589"}


id: GO:0003781
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete actin bundling activity (obsolete GO:0003781)","synonyms":[{"name":"actin bundling activity","type":"exact"}],"termid":"GO:0003781"}


id: PBO:0035755
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_rate_of_medial_membrane_band_assembly","termid":"PBO:0035755"}


id: PR:O74879
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A nucleolar protein 10 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04196","PANTHER:PTHR14927:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein enp2 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC330.09","secondary_identifiers":["UniProtKB:O74879"],"synonyms":[{"name":"Spom972h-NOL10","type":"exact"}],"termid":"PR:O74879"}


id: GO:0021684
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.","definition_xrefs":["GOC:dph","GOC:dgh","GOC:jid","GOC:cls","GO_REF:0000021","ISBN:0838580343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"cerebellar granular layer morphogenesis","termid":"GO:0021683"},{"relation_name":"part_of","term_name":"cerebellar cortex formation","termid":"GO:0021697"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cerebellar granular layer formation","termid":"GO:0021684"}


id: MONDO:0004268
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete subareolar duct papillomatosis (obsolete MONDO:0004268)","secondary_identifiers":["DOID:7533"],"synonyms":[{"name":"subareolar duct papillomatosis","type":"exact"}],"termid":"MONDO:0004268","xrefs":{"Monarch":{"xref_id":"0004268"}}}


id: MONDO:0035448
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A group of rare central nervous system malformations characterized by varying degrees of absence or dysplasia of the derivatives of the prosencephalon (i. e. telencephalon and diencephalon), with an intact cranial vault. The spectrum comprises atelencephaly, the less severe form, in which only the telencephalon is affected, and aprosencephaly, where the diencephalon is also involved. The malformations may occur in an isolated form or in association with other anomalies. [Orphanet:566847]","definition_xrefs":["Orphanet:566847"],"gene_count":0,"genotype_count":0,"name":"obsolete aprosencephaly/atelencephaly spectrum (obsolete MONDO:0035448)","termid":"MONDO:0035448","xrefs":{"Monarch":{"xref_id":"0035448"}}}


id: GO:0098032
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A fiber attached to the collar structure of some icosahedral viral capsids.","definition_xrefs":["GOC:bm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral capsid, fiber","termid":"GO:0098022"},{"relation_name":"part_of","term_name":"icosahedral viral capsid, collar","termid":"GO:0098031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"icosahedral viral capsid, collar fiber","termid":"GO:0098032"}


id: GO:0120009
data:
  {"annotated_genes":["SJAG_03741","SJAG_01722","SJAG_03338","SJAG_00230","SJAG_00576","SJAG_05268","SJAG_03721","SJAG_04370","SJAG_00355","SJAG_01305","SJAG_03710","SJAG_03746","SJAG_01329","SJAG_02375","SJAG_03718","SJAG_02323","SJAG_01590","SJAG_03851","SJAG_03416","SJAG_01229","SJAG_01225","SJAG_16459","SJAG_03172"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[57461,94006,102363,107956,109114,111076,115961],"is_not":false,"summary":null,"term":"GO:0120009"},{"annotations":[108405,88988,107274,107400,97310,115984,100284,105609,90665,106497,101038,98386,103797,109276,97249],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120010"},{"annotations":[106087],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120011"}]},"cv_name":"biological_process","definition":"The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).","definition_xrefs":["GOC:krc","PMID:24220498","PMID:20823909","PMID:25797198"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid transport","termid":"GO:0006869"},{"relation_name":"is_a","term_name":"membrane organization","termid":"GO:0061024"}],"gene_count":23,"genes_by_uniquename":{"SJAG_00230":null,"SJAG_00355":null,"SJAG_00576":null,"SJAG_01225":null,"SJAG_01229":null,"SJAG_01305":null,"SJAG_01329":null,"SJAG_01590":null,"SJAG_01722":null,"SJAG_02323":null,"SJAG_02375":null,"SJAG_03172":null,"SJAG_03338":null,"SJAG_03416":null,"SJAG_03710":null,"SJAG_03718":null,"SJAG_03721":null,"SJAG_03741":null,"SJAG_03746":null,"SJAG_03851":null,"SJAG_04370":null,"SJAG_05268":null,"SJAG_16459":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0061024","GO:0006810"],"is_obsolete":false,"name":"intermembrane lipid transfer","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000108":null},"termid":"GO:0120009","terms_by_termid":{"GO:0120009":null,"GO:0120010":null,"GO:0120011":null}}


id: FYPO:0007751
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but does not elongate normally or completely, and collapses during prometaphase I. Upon collapse the spindle may break or shrink.","definition_xrefs":["PMID:32723864","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spindle collapse during meiosis I","termid":"FYPO:0007103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0000631"],"is_obsolete":false,"name":"spindle collapse during meiotic prometaphase I","synonyms":[{"name":"broken meiotic spindle during prometaphase I","type":"related"},{"name":"meiosis I spindle collapse during prometaphase","type":"exact"},{"name":"meiotic spindle breakage during prometaphase I","type":"exact"},{"name":"meiotic spindle collapse during prometaphase I","type":"exact"},{"name":"spindle collapse during prometaphase I","type":"exact"},{"name":"spindle collapse during prometaphase of meiosis I","type":"exact"}],"termid":"FYPO:0007751"}


id: PBO:0027808
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_KT5720","termid":"PBO:0027808"}


id: PBO:0089827
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial heat shock protein Hsp78","termid":"PBO:0089827"}


id: MONDO:0007786
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete hypertrichosis lanuginosa congenita (obsolete MONDO:0007786)","termid":"MONDO:0007786","xrefs":{"Monarch":{"xref_id":"0007786"}}}


id: GO:0006987
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response.","definition_xrefs":["GOC:mah","GOC:tb","GOC:dph","PMID:12042763"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of signaling protein activity involved in unfolded protein response (obsolete GO:0006987)","synonyms":[{"name":"unfolded protein response, activation of signaling protein activity","type":"exact"},{"name":"unfolded protein response, activation of signaling protein kinase/endonuclease","type":"exact"},{"name":"unfolded protein response, activation of signalling protein kinase/endonuclease","type":"exact"}],"termid":"GO:0006987"}


id: MONDO:0018941
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Furuncular myiasis in humans is caused by two species: the Cayor worm (larvae of the African tumbu fly Cordylobia anthropophaga) and the larvae of the human botfly (Dermatobia hominis).","definition_xrefs":["Orphanet:591"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cutaneous myiasis","termid":"MONDO:0020568"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"furuncular myiasis","secondary_identifiers":["GARD:2418","icd11.foundation:1861376017","MESH:C538194","MEDGEN:419893","UMLS:C2931766"],"synonyms":[{"name":"furunculoid myiasis","type":"exact"},{"name":"furunculous myiasis","type":"exact"}],"termid":"MONDO:0018941","xrefs":{"Monarch":{"xref_id":"0018941"}}}


id: PBO:0065305
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine protease 22","termid":"PBO:0065305"}


id: PBO:0068585
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U2 small nuclear 36, pseudogene","termid":"PBO:0068585"}


id: GO:0045304
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to stimulus","termid":"GO:0048583"},{"relation_name":"is_a","term_name":"regulation of cellular process","termid":"GO:0050794"},{"relation_name":"regulates","term_name":"establishment of competence for transformation","termid":"GO:0030420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of establishment of competence for transformation","synonyms":[{"name":"regulator of establishment of competence for transformation activity","type":"related"}],"termid":"GO:0045304"}


id: GO:0031418
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vitamin binding","termid":"GO:0019842"},{"relation_name":"is_a","term_name":"carboxylic acid binding","termid":"GO:0031406"},{"relation_name":"is_a","term_name":"monosaccharide binding","termid":"GO:0048029"},{"relation_name":"is_a","term_name":"heterocyclic compound binding","termid":"GO:1901363"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"L-ascorbic acid binding","synonyms":[{"name":"L-ascorbate binding","type":"exact"},{"name":"vitamin C binding","type":"exact"}],"termid":"GO:0031418"}


id: PR:Q9HDX2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An L-lactate dehydrogenase [cytochrome] that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01244","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized lactate 2-monooxygenase PB1A11.03 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB1A11.03","secondary_identifiers":["UniProtKB:Q9HDX2"],"synonyms":[{"name":"Spom972h-lldD","type":"exact"}],"termid":"PR:Q9HDX2"}


id: FYPO:0007348
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone H3-K36 methylation during vegetative growth","termid":"FYPO:0002918"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0002494"],"is_obsolete":false,"name":"decreased histone H3-K36 trimethylation during vegetative growth","synonyms":[{"name":"decreased histone H3 K36 trimethylation during vegetative growth","type":"exact"},{"name":"decreased histone H3-K36 trimethylation during mitotic cell cycle","type":"related"},{"name":"decreased histone H3K36me3 during vegetative growth","type":"exact"},{"name":"decreased histone lysine H3 K36 trimethylation during vegetative growth","type":"exact"},{"name":"reduced histone H3-K36 trimethylation during vegetative growth","type":"exact"}],"termid":"FYPO:0007348"}


id: MONDO:1012539
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hypomyelinating leukodystrophy, non-human animal","termid":"MONDO:1011898"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypomyelinating leukodystrophy, dog","secondary_identifiers":["OMIA:002321-9615"],"termid":"MONDO:1012539","xrefs":{"Monarch":{"xref_id":"1012539"}}}


id: PBO:0000480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol phosphorylceramide synthase Aur1 (predicted)","termid":"PBO:0000480"}


id: GO:0030720
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.","definition_xrefs":["PMID:10449356","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"localization of cell","termid":"GO:0051674"},{"relation_name":"part_of","term_name":"germarium-derived egg chamber formation","termid":"GO:0007293"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"oocyte localization involved in germarium-derived egg chamber formation","synonyms":[{"name":"establishment and maintenance of oocyte localization in egg chamber","type":"exact"},{"name":"establishment and maintenance of oocyte position during oogenesis","type":"exact"},{"name":"oocyte localisation involved in germarium-derived egg chamber formation","type":"exact"},{"name":"oocyte localization during germarium-derived egg chamber formation","type":"related"},{"name":"oocyte localization during oogenesis","type":"related"},{"name":"oocyte positioning during oogenesis","type":"narrow"},{"name":"oogenesis, establishment and maintenance of oocyte localization","type":"exact"},{"name":"oogenesis, oocyte localization","type":"exact"}],"termid":"GO:0030720"}


id: MONDO:0010615
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"isolated congenital growth hormone deficiency","termid":"MONDO:0000050"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"isolated growth hormone deficiency type III","secondary_identifiers":["DOID:0060875","UMLS:C0472813","Orphanet:231692","SCTID:234533006","OMIM:307200","GARD:3921","MEDGEN:141630","MESH:C537149"],"synonyms":[{"name":"Fleisher syndrome","type":"exact"},{"name":"Growth hormone deficiency with hypogammaglobulinemia","type":"related"},{"name":"IGHD 3","type":"related"},{"name":"IGHD III","type":"exact"},{"name":"IGHD3","type":"related"},{"name":"X-linked IGHD","type":"exact"},{"name":"X-linked agammaglobulinemia and isolated growth hormone deficiency","type":"exact"},{"name":"X-linked hypogammaglobulinemia and isolated growth hormone deficiency","type":"exact"},{"name":"X-linked isolated growth hormone deficiency","type":"exact"},{"name":"agammaglobulinemia and isolated Growth hormone deficiency, X-linked","type":"related"},{"name":"congenital IGHD type III","type":"exact"},{"name":"congenital isolated GH deficiency type III","type":"exact"},{"name":"congenital isolated growth hormone deficiency type III","type":"exact"},{"name":"growth hormone deficiency with hypogammaglobulinemia","type":"exact"},{"name":"hypogammaglobulinemia and isolated Growth hormone deficiency, X-linked","type":"related"},{"name":"isolated growth hormone deficiency type 3","type":"related"},{"name":"isolated growth hormone deficiency type III","type":"exact"},{"name":"isolated growth hormone deficiency, type 3","type":"related"},{"name":"isolated growth hormone deficiency, type III","type":"related"},{"name":"isolated growth hormone deficiency, type IIi, with agammaglobulinemia, X-linked recessive","type":"exact"}],"termid":"MONDO:0010615","xrefs":{"Monarch":{"xref_id":"0010615"}}}


id: PBO:0029274
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_chromatin_at_MCB_promoters_during_cellular_response_to_hydroxyurea","termid":"PBO:0029274"}


id: GO:0102544
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: L-ornithinium(1+) + 2-oxoglutarate + NADPH + H+ = ornaline + NADP + H2O.","definition_xrefs":["MetaCyc:RXN-14880","EC:1.5.1.-","GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete ornaline synthase activity (obsolete GO:0102544)","termid":"GO:0102544"}


id: PBO:0028389
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_methylglyoxal","termid":"PBO:0028389"}


id: GO:0047135
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP+ = bis-gamma-glutamylcystine + H+ + NADPH.","definition_xrefs":["RHEA:11980","EC:1.8.1.13"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor","termid":"GO:0016668"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"bis-gamma-L-glutamylcystine reductase (NADPH) activity","secondary_identifiers":["MetaCyc:1.6.4.9-RXN","KEGG_REACTION:R02742"],"synonyms":[{"name":"Bis-gamma-glutamylcystine reductase (NADPH)","type":"related"},{"name":"NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity","type":"related"},{"name":"NADPH:bis-gamma-glutamylcysteine oxidoreductase activity","type":"related"},{"name":"bis-g-glutamylcystine reductase (NADPH) activity","type":"exact"},{"name":"bis-gamma-glutamylcystine reductase (NADPH) activity","type":"related"},{"name":"gamma-glutamylcysteine:NADP+ oxidoreductase activity","type":"related"}],"termid":"GO:0047135"}


id: GO:0036200
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: androsta-1,4-diene-3,17-dione + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].","definition_xrefs":["EC:1.14.15.30"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016713"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"3-ketosteroid 9-alpha-monooxygenase activity","secondary_identifiers":["RHEA:32199","KEGG_REACTION:R09860"],"synonyms":[{"name":"3-ketosteroid 9alpha-hydroxylase activity","type":"related"},{"name":"KshAB activity","type":"related"}],"termid":"GO:0036200"}


id: PBO:0042586
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebellar degeneration related protein 2","termid":"PBO:0042586"}


id: PBO:0031477
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-delayed_onset_of_actin_cortical_patch_internalization","termid":"PBO:0031477"}


id: GO:0070315
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.","definition_xrefs":["ISBN:0815316194","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G1 to G0 transition","termid":"GO:0070314"},{"relation_name":"part_of","term_name":"cell differentiation","termid":"GO:0030154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"G1 to G0 transition involved in cell differentiation","synonyms":[{"name":"G1/G0 transition involved in cell differentiation","type":"exact"}],"termid":"GO:0070315"}


id: MONDO:0018549
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete late-onset scapuloperoneal muscular dystrophy with hyaline bodies (obsolete MONDO:0018549)","secondary_identifiers":["Orphanet:431263"],"synonyms":[{"name":"late-onset SPMD with hyaline bodies","type":"exact"},{"name":"late-onset scapuloperoneal syndrome, myopathic type","type":"exact"}],"termid":"MONDO:0018549","xrefs":{"Monarch":{"xref_id":"0018549"}}}


id: PBO:0049389
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTP binding protein 2","termid":"PBO:0049389"}


id: PBO:0090406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GATOR2-SEACAT complex/COPII-coated vesicle component/nuclear pore outer ring WD repeat protein Sec13","termid":"PBO:0090406"}


id: FYPO:0003306
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the mitotic index is lower than normal. The mitotic index is the proportion of the population undergoing mitosis at any given time.","definition_xrefs":["PMID:11683392","PMID:22684255","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0001985"],"is_obsolete":false,"name":"decreased mitotic index","synonyms":[{"name":"reduced mitotic index","type":"exact"}],"termid":"FYPO:0003306"}


id: FYPO:0003624
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues of one or more specific proteins is decreased during a cellular response to heat.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete decreased protein threonine phosphorylation during cellular response to heat (obsolete FYPO:0003624)","synonyms":[{"name":"decreased protein threonine phosphorylation during cellular response to heat during mitotic cell cycle","type":"related"},{"name":"decreased protein threonine phosphorylation during cellular response to heat during vegetative growth","type":"exact"},{"name":"reduced protein threonine phosphorylation during cellular response to heat","type":"exact"}],"termid":"FYPO:0003624"}


id: MONDO:1012545
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"choroid plexus tumour, non-human animal","termid":"MONDO:1011825"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"choroid plexus tumour, dog","secondary_identifiers":["OMIA:002403-9615"],"termid":"MONDO:1012545","xrefs":{"Monarch":{"xref_id":"1012545"}}}


id: GO:0015917
data:
  {"annotated_genes":["SJAG_00669","SJAG_04370"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[74450],"is_not":false,"summary":null,"term":"GO:0015917"},{"annotations":[68448],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140331"}]},"cv_name":"biological_process","definition":"The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid transport","termid":"GO:0015914"},{"relation_name":"is_a","term_name":"nitrogen compound transport","termid":"GO:0071705"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00669":null,"SJAG_04370":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"aminophospholipid transport","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000108":null},"termid":"GO:0015917","terms_by_termid":{"GO:0015917":null,"GO:0140331":null}}


id: PATO:0002630
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An occurrence quality inhering in a bearer by virtue of the bearer's having a course that occurs occasionally.","definition_xrefs":["PATO:MAH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"occurrence","termid":"PATO:0000057"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"episodic","termid":"PATO:0002630"}


id: GO:0099092
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"postsynaptic specialization, intracellular component","termid":"GO:0099091"},{"relation_name":"part_of","term_name":"postsynaptic density","termid":"GO:0014069"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"postsynaptic density, intracellular component","termid":"GO:0099092"}


id: GO:0042725
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"water-soluble vitamin catabolic process","termid":"GO:0042365"},{"relation_name":"is_a","term_name":"thiamine-containing compound metabolic process","termid":"GO:0042723"},{"relation_name":"is_a","term_name":"sulfur compound catabolic process","termid":"GO:0044273"},{"relation_name":"is_a","term_name":"pyrimidine-containing compound catabolic process","termid":"GO:0072529"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006766"},{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006790","GO:0044248","GO:0006766"],"is_obsolete":false,"name":"thiamine-containing compound catabolic process","synonyms":[{"name":"thiamin and derivative catabolic process","type":"exact"},{"name":"thiamin and derivative catabolism","type":"exact"},{"name":"thiamin-containing compound catabolic process","type":"exact"},{"name":"thiamine and derivative catabolic process","type":"exact"},{"name":"thiamine and derivative catabolism","type":"exact"},{"name":"thiamine-containing compound breakdown","type":"exact"},{"name":"thiamine-containing compound catabolism","type":"exact"},{"name":"thiamine-containing compound degradation","type":"exact"},{"name":"vitamin B1 and derivative catabolic process","type":"exact"},{"name":"vitamin B1 and derivative catabolism","type":"exact"}],"termid":"GO:0042725"}


id: PBO:0040532
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beta-1,3-N-acetylgalactosaminyltransferase 2","termid":"PBO:0040532"}


id: PBO:0077571
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMEM276-ZFTRAF1 readthrough","termid":"PBO:0077571"}


id: GO:0047998
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate.","definition_xrefs":["RHEA:12629","EC:1.14.11.11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"hyoscyamine (6S)-dioxygenase activity","secondary_identifiers":["KEGG_REACTION:R03812","MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN"],"synonyms":[{"name":"L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)","type":"related"},{"name":"hyoscyamine (6S)-hydroxylase activity","type":"related"},{"name":"hyoscyamine 6-beta-hydroxylase activity","type":"related"},{"name":"hyoscyamine 6-hydroxylase activity","type":"related"},{"name":"hyoscyamine 6beta-dioxygenase activity","type":"related"},{"name":"hyoscyamine 6beta-hydroxylase activity","type":"related"}],"termid":"GO:0047998"}


id: PBO:0043665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coenzyme Q8B","termid":"PBO:0043665"}


id: PBO:0041272
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complement C1q like 4","termid":"PBO:0041272"}


id: FYECO:0000131
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which ubiquinone Q6 was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ ubiquinone Q6","synonyms":[{"name":"coenzyme Q6 added","type":"exact"}],"termid":"FYECO:0000131"}


id: PBO:0067102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 144, pseudogene","termid":"PBO:0067102"}


id: MOD:00120
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form meso-lanthionine.","definition_xrefs":["RESID:AA0111","PubMed:15023056","PubMed:3769923"],"direct_ancestors":[{"relation_name":"is_a","term_name":"crosslinked residues with loss of water","termid":"MOD:00954"},{"relation_name":"is_a","term_name":"lanthionine","termid":"MOD:01841"},{"relation_name":"is_a","term_name":"crosslinked L-serine residue","termid":"MOD:02055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"meso-lanthionine","synonyms":[{"name":"(2R,2'S)-3,3'-sulfanediylbis(2-aminopropanoic acid)","type":"exact"},{"name":"(2R,2'S)-3,3'-thiobis-(2-aminopropanoic acid)","type":"exact"},{"name":"(2R,6S)-2,6-diamino-4-thiaheptanedioic acid","type":"exact"},{"name":"(2R,6S)-meso-lanthionine","type":"exact"},{"name":"(2S)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]sulfanyl]propanoic acid","type":"exact"},{"name":"(2S,6R)-meso-lanthionine","type":"related"},{"name":"(R)-S-(2-amino-2-carboxyethyl)-D-cysteine","type":"exact"},{"name":"(R,S)-bis(2-amino-2-carboxyethyl)sulfide","type":"exact"},{"name":"3,3'-thiobis-meso-alanine","type":"exact"},{"name":"CROSSLNK Lanthionine (Cys-Ser)","type":"exact"},{"name":"CROSSLNK Lanthionine (Ser-Cys)","type":"exact"},{"name":"XLNK-SCys-(D)3Dha","type":"exact"},{"name":"cysteine-3-D-alanine thioether","type":"exact"},{"name":"meso-lanthionine","type":"exact"}],"termid":"MOD:00120"}


id: GO:0003839
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.","definition_xrefs":["PMID:18515354"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amidine-lyase activity","termid":"GO:0016842"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"gamma-glutamylcyclotransferase activity","secondary_identifiers":["MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN","Reactome:R-HSA-1247922","Reactome:R-HSA-6785928","EC:4.3.2.9","RHEA:20505"],"synonyms":[{"name":"(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)","type":"exact"},{"name":"L-glutamic cyclase activity","type":"exact"},{"name":"gamma-L-glutamylcyclotransferase activity","type":"exact"},{"name":"gamma-glutamyl-amino acid cyclotransferase activity","type":"exact"}],"termid":"GO:0003839"}


id: GO:0023020
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another.","definition_xrefs":["GOC:mtg_signal"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of gene expression as a consequence of T cell signal transmission (obsolete GO:0023020)","synonyms":[{"name":"regulation of gene expression as a consequence of T cell signal transmission","type":"exact"}],"termid":"GO:0023020"}


id: MONDO:0000455
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited ocular disorder characterized by the loss of cone cells, the photoreceptors responsible for both central and color vision.","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary macular dystrophy","termid":"MONDO:0020242"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cone dystrophy","secondary_identifiers":["Orphanet:1871","GARD:11897","DOID:0050795","ICD9:362.75","NANDO:1200936","NORD:991","MESH:D000077765","SCTID:312917007","MEDGEN:676499","UMLS:C0730290"],"synonyms":[{"name":"cone dystrophy","type":"exact"},{"name":"progressive cone dystrophy","type":"narrow"},{"name":"retinal cone dystrophy","type":"related"},{"name":"stationary cone dystrophy","type":"narrow"}],"termid":"MONDO:0000455","xrefs":{"Monarch":{"xref_id":"0000455"}}}


id: PBO:0029843
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_acetylation","termid":"PBO:0029843"}


id: PBO:0087892
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcription coactivator; component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes","termid":"PBO:0087892"}


id: GO:0099625
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.","definition_xrefs":["GOC:BHF","GOC:mtg_cardiac_conduct_nov11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiac muscle cell membrane repolarization","termid":"GO:0099622"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ventricular cardiac muscle cell membrane repolarization","termid":"GO:0099625"}


id: MONDO:1010281
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Testicular regression syndrome that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypertrophic cardiomyopathy, non-human animal","termid":"MONDO:1010015"},{"relation_name":"is_a","term_name":"hypogonadism, non-human animal","termid":"MONDO:1010276"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis, non-human animal","termid":"MONDO:1011313"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testicular regression syndrome, non-human animal","secondary_identifiers":["OMIA:001535"],"termid":"MONDO:1010281","xrefs":{"Monarch":{"xref_id":"1010281"}}}


id: GO:0008156
data:
  {"annotated_genes":["SJAG_02162","SJAG_03048","SJAG_01068","SJAG_01210","SJAG_04855","SJAG_00247","SJAG_03097","SJAG_04671","SJAG_02724","SJAG_03997"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[116590],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903464"},{"annotations":[97528,102120,108647],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903467"},{"annotations":[102979],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:1902681"},{"annotations":[108272,99123,106392,102980],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0011000"},{"annotations":[102030,114767,99124],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031582"},{"annotations":[99125],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090001"},{"annotations":[102031],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071807"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of DNA replication","termid":"GO:0006275"},{"relation_name":"is_a","term_name":"negative regulation of DNA metabolic process","termid":"GO:0051053"},{"relation_name":"negatively_regulates","term_name":"DNA replication","termid":"GO:0006260"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00247":null,"SJAG_01068":null,"SJAG_01210":null,"SJAG_02162":null,"SJAG_02724":null,"SJAG_03048":null,"SJAG_03097":null,"SJAG_03997":null,"SJAG_04671":null,"SJAG_04855":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006260"},{"rel_name":"negatively_regulates","termid":"GO:0006260"},{"rel_name":"regulates","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006260","GO:0008150","GO:0006259"],"is_obsolete":false,"name":"negative regulation of DNA replication","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"DNA replication inhibitor","type":"related"},{"name":"down regulation of DNA replication","type":"exact"},{"name":"down-regulation of DNA replication","type":"exact"},{"name":"downregulation of DNA replication","type":"exact"},{"name":"inhibition of DNA replication","type":"narrow"}],"termid":"GO:0008156","terms_by_termid":{"GO:0011000":null,"GO:0031582":null,"GO:0071807":null,"GO:0090001":null,"GO:1902681":null,"GO:1903464":null,"GO:1903467":null}}


id: PBO:0030229
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_steady-state_intracellular_calcium_level_following_extracellular_calcium_stimulus","termid":"PBO:0030229"}


id: MONDO:1011495
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ehlers-Danlos syndrome that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Ehlers-Danlos syndrome, non-human animal","termid":"MONDO:1011425"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ehlers-Danlos syndrome, horse","secondary_identifiers":["OMIA:000327-9796"],"termid":"MONDO:1011495","xrefs":{"Monarch":{"xref_id":"1011495"}}}


id: PBO:0071843
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S2 pseudogene 38","termid":"PBO:0071843"}


id: MONDO:0011397
data:
  {"annotated_genes":["SJAG_02119"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86567],"is_not":false,"summary":null,"term":"MONDO:0011397"}]},"cv_name":"mondo","definition":"Autosomal dominant cerebellar ataxia, deafness and narcolepsy (ADCA-DN) is a polymorphic disorder and a subtype of autosomal dominant cerebellar ataxia type 1 (ADCA type 1) characterized by ataxia, sensorineural deafness and narcolepsy with cataplexy and dementia.","definition_xrefs":["Orphanet:314404"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sleep-wake disorder","termid":"MONDO:0003406"},{"relation_name":"is_a","term_name":"autosomal dominant cerebellar ataxia type I","termid":"MONDO:0019792"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02119":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0002039","MONDO:0005559","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant cerebellar ataxia, deafness and narcolepsy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C3807295","MEDGEN:813625","GARD:12372","DOID:0050968","OMIM:604121"],"synonyms":[{"name":"ADCA-DN","type":"related"},{"name":"ADCA-DN syndrome","type":"exact"},{"name":"ADCADN","type":"related"},{"name":"autosomal dominant cerebellar ataxia, deafness and narcolepsy","type":"exact"},{"name":"autosomal dominant cerebellar ataxia, deafness, and narcolepsy","type":"related"},{"name":"autosomal dominant cerebellar ataxia-deafness-narcolepsy syndrome","type":"related"},{"name":"cerebellar ataxia, deafness, and narcolepsy, autosomal dominant","type":"related"}],"termid":"MONDO:0011397","terms_by_termid":{"MONDO:0011397":null},"xrefs":{"Monarch":{"xref_id":"0011397"}}}


id: PBO:0061729
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear RNA export factor 2B","termid":"PBO:0061729"}


id: PBO:0024811
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-causal_relation_between_material_entity_and_a_process","termid":"PBO:0024811"}


id: FYECO:0000438
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in minimal media containing minimal glutamate plus thiamine.","definition_xrefs":["PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping defined medium","termid":"FYECO:0000013"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ePMGT","secondary_identifiers":["PMID:38133430"],"termid":"FYECO:0000438"}


id: PBO:0049399
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gametocyte specific factor 1 like","termid":"PBO:0049399"}


id: GO:0034242
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"negative regulation of cellular component organization","termid":"GO:0051129"},{"relation_name":"is_a","term_name":"regulation of syncytium formation by plasma membrane fusion","termid":"GO:0060142"},{"relation_name":"negatively_regulates","term_name":"syncytium formation by plasma membrane fusion","termid":"GO:0000768"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of syncytium formation by plasma membrane fusion","termid":"GO:0034242"}


id: GO:0047635
data:
  {"annotated_genes":["SJAG_04145"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[110984],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004021"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.","definition_xrefs":["MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN","EC:2.6.1.12"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transaminase activity","termid":"GO:0008483"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04145":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016769"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016769"],"is_obsolete":false,"name":"alanine-oxo-acid transaminase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["RHEA:19953"],"synonyms":[{"name":"L-alanine-alpha-keto acid aminotransferase activity","type":"related"},{"name":"L-alanine:2-oxo-acid aminotransferase activity","type":"related"},{"name":"alanine--oxo-acid aminotransferase activity","type":"related"},{"name":"alanine-keto acid aminotransferase activity","type":"related"},{"name":"alanine-oxo acid aminotransferase activity","type":"related"},{"name":"alanine-oxo-acid aminotransferase activity","type":"exact"},{"name":"leucine-alanine transaminase activity","type":"related"}],"termid":"GO:0047635","terms_by_termid":{"GO:0004021":null}}


id: PR:P41888
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- tnr3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P41888"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thiamine pyrophosphokinase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC6F12.05c","synonyms":[{"name":"Spom972h-tnr3","type":"exact"},{"name":"TPK (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"thiamine kinase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P41888"}


id: PBO:0029589
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_RNA_binding","termid":"PBO:0029589"}


id: PBO:0017853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amino acid transmembrane transporter Aat1","termid":"PBO:0017853"}


id: GO:0052026
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont alters or subverts transcription in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host gene expression","termid":"GO:0039656"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host transcription","synonyms":[{"name":"modulation by symbiont of host transcription","type":"exact"}],"termid":"GO:0052026"}


id: PBO:0063807
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphorylase kinase regulatory subunit beta pseudogene 2","termid":"PBO:0063807"}


id: GO:0007295
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.","definition_xrefs":["ISBN:0879694238","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"is_a","term_name":"developmental growth","termid":"GO:0048589"},{"relation_name":"part_of","term_name":"oogenesis","termid":"GO:0048477"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"growth of a germarium-derived egg chamber","synonyms":[{"name":"egg chamber growth","type":"exact"}],"termid":"GO:0007295"}


id: FYPO:0001278
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein complex assembly during vegetative growth","termid":"FYPO:0001215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000257","FYPO:0001312","FYPO:0000002"],"is_obsolete":false,"name":"normal MCM complex assembly","synonyms":[{"name":"normal MCM complex assembly during mitotic cell cycle","type":"related"},{"name":"normal MCM complex assembly during vegetative growth","type":"exact"}],"termid":"FYPO:0001278"}


id: MONDO:0006905
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, small and slightly elevated brown or black skin lesion with usually well-demarcated borders. It is characterized by the presence of a melanocytic proliferation resulting in the formation of uniform cellular nests. Sometimes the clinical and morphologic features may be difficult to distinguish from melanoma.","definition_xrefs":["NCIT:C4751"],"direct_ancestors":[{"relation_name":"is_a","term_name":"melanocytic nevus","termid":"MONDO:0005073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"pigmented spindle cell nevus","secondary_identifiers":["UMLS:C0474967","MESH:D018331","SCTID:254812004","MEDGEN:105378"],"synonyms":[{"name":"spindle cell Nevus of Reed","type":"exact"}],"termid":"MONDO:0006905","xrefs":{"Monarch":{"xref_id":"0006905"}}}


id: PBO:0001987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamate synthase Glt1 (predicted)","termid":"PBO:0001987"}


id: PBO:0038788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosine deaminase 2","termid":"PBO:0038788"}


id: PBO:0089071
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial phospholipid scramblase","termid":"PBO:0089071"}


id: GO:0035194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.","definition_xrefs":["PMID:18771919","PMID:11201747","PMID:11713190","PMID:15066275","PMID:33184244","PMID:15020054","GOC:ems","PMID:32885814"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-transcriptional gene silencing","termid":"GO:0016441"},{"relation_name":"is_a","term_name":"regulatory ncRNA-mediated gene silencing","termid":"GO:0031047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulatory ncRNA-mediated post-transcriptional gene silencing","secondary_identifiers":["GO:0016246","Reactome:R-HSA-426496","Wikipedia:RNA_interference"],"synonyms":[{"name":"PTGS","type":"broad"},{"name":"RNA interference","type":"broad"},{"name":"RNA-dependent post-transcriptional gene silencing","type":"exact"},{"name":"RNA-mediated post-transcriptional gene silencing","type":"exact"},{"name":"RNA-mediated posttranscriptional gene silencing","type":"exact"},{"name":"RNAi","type":"broad"},{"name":"cosuppression","type":"related"},{"name":"ncRNA-mediated post-transcriptional gene silencing","type":"exact"},{"name":"post-transcriptional gene silencing by RNA","type":"related"},{"name":"posttranscriptional gene silencing by RNA","type":"exact"},{"name":"quelling","type":"related"}],"termid":"GO:0035194"}


id: PBO:0044824
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 110","termid":"PBO:0044824"}


id: PBO:0082101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AAA ATPase and SNARE disassembly chaperone; required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, autophagy, and protein secretion; releases Sec17p from SNAP complexes; has similarity to mammalian N-ethylmaleimide-sensitive factor (NSF)","termid":"PBO:0082101"}


id: PBO:0061985
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 2 subfamily B member 4 pseudogene","termid":"PBO:0061985"}


id: MONDO:0019490
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A hereditary cardiac conduction disorder that may progress to complete atrioventricular (AV) block. The disease is either asymptomatic or manifests as dyspnea, dizziness, syncope, abdominal pain, heart failure or sudden death.","definition_xrefs":["Orphanet:871"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart conduction disease","termid":"MONDO:0000992"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"progressive familial heart block","secondary_identifiers":["ICD9:426.6","DOID:0111073","SCTID:93130009","GARD:10005","OMIMPS:113900","SCTID:698249005"],"synonyms":[{"name":"PFHB","type":"exact"},{"name":"familial Lenegre disease","type":"exact"},{"name":"familial Lenègre disease","type":"exact"},{"name":"familial Lev disease","type":"exact"},{"name":"familial Lev-Lenegre disease","type":"exact"},{"name":"familial Lev-Lenègre disease","type":"exact"},{"name":"familial PCCD","type":"exact"},{"name":"familial progressive cardiac conduction defect","type":"related"},{"name":"familial progressive heart block","type":"exact"},{"name":"hereditary bundle branch defect","type":"narrow"}],"termid":"MONDO:0019490","xrefs":{"Monarch":{"xref_id":"0019490"}}}


id: GO:0019877
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.","definition_xrefs":["GOC:ma","ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid biosynthetic process","termid":"GO:0008652"},{"relation_name":"is_a","term_name":"dicarboxylic acid biosynthetic process","termid":"GO:0043650"},{"relation_name":"is_a","term_name":"diaminopimelate metabolic process","termid":"GO:0046451"},{"relation_name":"is_a","term_name":"fatty acid derivative biosynthetic process","termid":"GO:1901570"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0008150","GO:0006629","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"diaminopimelate biosynthetic process","synonyms":[{"name":"diaminopimelate anabolism","type":"exact"},{"name":"diaminopimelate biosynthesis","type":"exact"},{"name":"diaminopimelate formation","type":"exact"},{"name":"diaminopimelate synthesis","type":"exact"}],"termid":"GO:0019877"}


id: GO:0018699
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl.","definition_xrefs":["UM-BBD_reactionID:r1007"],"gene_count":0,"genotype_count":0,"name":"obsolete 1,1,1-trichloroethane reductive dehalogenase activity (obsolete GO:0018699)","termid":"GO:0018699"}


id: PBO:0053504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 487","termid":"PBO:0053504"}


id: FYPO:0004059
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which reciprocal meiotic recombination is normal (i.e. indistinguishable from wild type) at an CRE promoter in a chromosome.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal meiotic recombination","termid":"FYPO:0000488"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal meiotic recombination at CRE promoter","synonyms":[{"name":"normal meiotic recombination at M26 binding site","type":"exact"}],"termid":"FYPO:0004059"}


id: MONDO:0007585
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any exostoses, multiple in which the cause of the disease is a mutation in the EXT1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary multiple osteochondromas","termid":"MONDO:0005508"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exostoses, multiple, type 1","secondary_identifiers":["GARD:2204","OMIM:133700"],"synonyms":[{"name":"EXT","type":"related"},{"name":"EXT1 exostoses, multiple","type":"exact"},{"name":"diaphyseal Aclasis","type":"related"},{"name":"exostoses, multiple caused by mutation in EXT1","type":"exact"},{"name":"exostoses, multiple, type 1","type":"exact"},{"name":"exostoses, multiple, type I","type":"related"},{"name":"multiple cartilaginous exostoses","type":"related"},{"name":"multiple osteochondromas","type":"related"},{"name":"osteochondromatosis","type":"related"}],"termid":"MONDO:0007585","xrefs":{"Monarch":{"xref_id":"0007585"}}}


id: PBO:0113000
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha-factor mating pheromone made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor; binds copper(II) ions","termid":"PBO:0113000"}


id: MONDO:1012896
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hearing loss that occurs in pigs due to a mutation in the GJB2 gene created by genetic engineering or gene editing.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss disorder, non-human animal","termid":"MONDO:1012969"},{"relation_name":"is_a","term_name":"inherited auditory system disease, non-human animal","termid":"MONDO:1012970"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deafness, GJB2-related, pig","secondary_identifiers":["OMIA:002439-9823"],"termid":"MONDO:1012896","xrefs":{"Monarch":{"xref_id":"1012896"}}}


id: MONDO:0000053
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete macroglobulinemia, Waldenstrom (obsolete MONDO:0000053)","termid":"MONDO:0000053","xrefs":{"Monarch":{"xref_id":"0000053"}}}


id: PBO:0077488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 208","termid":"PBO:0077488"}


id: GO:0019101
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The determination of sex and sexual phenotypes in a female organism's soma.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"somatic sex determination","termid":"GO:0018993"},{"relation_name":"is_a","term_name":"female sex determination","termid":"GO:0030237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"female somatic sex determination","termid":"GO:0019101"}


id: GO:0015859
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside transport","termid":"GO:0015858"},{"relation_name":"is_a","term_name":"intracellular transport","termid":"GO:0046907"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"intracellular nucleoside transport","termid":"GO:0015859"}


id: SO:0000926
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An edit to insert a CU dinucleotide.","definition_xrefs":["SO:ke"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000926 insert_CU (obsolete SO:0000926)","synonyms":[{"name":"insert CU","type":"exact"}],"termid":"SO:0000926"}


id: PBO:0081707
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 627","termid":"PBO:0081707"}


id: PBO:0084655
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Minor sphingoid long-chain base kinase; possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules; LCB5 has a paralog, LCB4, that arose from the whole genome duplication","termid":"PBO:0084655"}


id: GO:1904405
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.","definition_xrefs":["GO_REF:0000071","PMID:9149109","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to aldehyde","termid":"GO:0110096"},{"relation_name":"is_a","term_name":"response to formaldehyde","termid":"GO:1904404"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to formaldehyde","termid":"GO:1904405"}


id: PBO:0085077
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes","termid":"PBO:0085077"}


id: GO:0034895
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate.","definition_xrefs":["UM-BBD_reactionID:r1398"],"gene_count":0,"genotype_count":0,"name":"obsolete pyridine-3,4-diol dioxygenase activity (obsolete GO:0034895)","termid":"GO:0034895"}


id: GO:0097087
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["GOC:rv","PMID:27901018"],"direct_ancestors":[{"relation_name":"is_a","term_name":"interleukin-17 production","termid":"GO:0032620"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"interleukin-17A production","secondary_identifiers":["GO:0150154"],"synonyms":[{"name":"IL-17A production","type":"exact"},{"name":"interleukin-17A biosynthetic process","type":"narrow"}],"termid":"GO:0097087"}


