# terms

id: GO:0051581
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of neurotransmitter uptake","termid":"GO:0051580"},{"relation_name":"is_a","term_name":"negative regulation of neurotransmitter transport","termid":"GO:0051589"},{"relation_name":"negatively_regulates","term_name":"neurotransmitter uptake","termid":"GO:0001504"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of neurotransmitter uptake","synonyms":[{"name":"down regulation of neurotransmitter uptake","type":"exact"},{"name":"down-regulation of neurotransmitter uptake","type":"exact"},{"name":"downregulation of neurotransmitter uptake","type":"exact"},{"name":"negative regulation of neurotransmitter import","type":"exact"}],"termid":"GO:0051581"}


id: MONDO:0024607
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A congenital muscular dystrophy characterized by onset of progressive muscle weakness in early childhood with autosomal recessive inheritance that has material basis in homozygous or compound heterozygous mutation in the INPP5K gene (607875) on chromosome 17p13.","definition_xrefs":["DOID:0080197"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital muscular dystrophy","termid":"MONDO:0019950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0005336"],"is_obsolete":false,"name":"congenital muscular dystrophy with cataracts and intellectual disability","secondary_identifiers":["Orphanet:662184","MEDGEN:1382291","OMIM:617404","UMLS:C4479410"],"synonyms":[{"name":"MDCCAID","type":"related"},{"name":"muscular dystrophy, congenital, with cataracts and intellectual disability","type":"related"}],"termid":"MONDO:0024607","xrefs":{"Monarch":{"xref_id":"0024607"}}}


id: MONDO:0013303
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autoimmune disease in which the cause of the disease is a mutation in the SIAE gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autoimmune disease, susceptibility to, 6","secondary_identifiers":["OMIM:613551","MEDGEN:462147","UMLS:C3150797"],"synonyms":[{"name":"AIS6","type":"related"},{"name":"SIAE autoimmune disease","type":"exact"},{"name":"autoimmune disease caused by mutation in SIAE","type":"exact"},{"name":"autoimmune disease, susceptibility to, 6","type":"exact"},{"name":"autoimmune disease, susceptibility to, type 6","type":"exact"},{"name":"susceptibility to autoimmune disease 6","type":"related"}],"termid":"MONDO:0013303","xrefs":{"Monarch":{"xref_id":"0013303"}}}


id: PBO:0077901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tryptase delta 1","termid":"PBO:0077901"}


id: PBO:0056696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiosis specific with coiled-coil domain","termid":"PBO:0056696"}


id: PR:Q9USW4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An acetyl-coenzyme A transporter 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO02941"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C21B10.09 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC21B10.09","secondary_identifiers":["UniProtKB:Q9USW4"],"synonyms":[{"name":"Spom972h-SLC33A1","type":"exact"}],"termid":"PR:Q9USW4"}


id: PBO:0056296
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule associated protein 1 light chain 3 alpha","termid":"PBO:0056296"}


id: PR:Q10340
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC106.19 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10340"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C106.19 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC106.19","synonyms":[{"name":"Spom972h-SPBC106.19","type":"exact"}],"termid":"PR:Q10340"}


id: PBO:0066271
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding motif protein Y-linked family 1 member E","termid":"PBO:0066271"}


id: GO:0035133
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-embryonic medial fin morphogenesis","termid":"GO:0035132"},{"relation_name":"is_a","term_name":"caudal fin morphogenesis","termid":"GO:0035143"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"post-embryonic caudal fin morphogenesis","termid":"GO:0035133"}


id: GO:0047134
data:
  {"annotated_genes":["SJAG_03653","SJAG_00489","SJAG_04399"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[60326],"is_not":false,"summary":null,"term":"GO:0047134"},{"annotations":[72969,79247],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004791"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.","definition_xrefs":["EC:1.8.1.8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-disulfide reductase activity","termid":"GO:0015035"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor","termid":"GO:0016668"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00489":null,"SJAG_03653":null,"SJAG_04399":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0015036"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0015036","GO:0140096","GO:0016491"],"is_obsolete":false,"name":"protein-disulfide reductase [NAD(P)H] activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:1.6.4.4-RXN"],"synonyms":[{"name":"NAD(P)H:protein-disulfide oxidoreductase activity","type":"related"},{"name":"disulfide reductase activity","type":"related"},{"name":"insulin-glutathione transhydrogenase activity","type":"related"},{"name":"protein disulfide reductase (NAD(P)H) activity","type":"exact"},{"name":"protein disulfide reductase activity","type":"related"},{"name":"protein disulphide reductase activity","type":"related"},{"name":"protein-disulfide reductase (NAD(P)) activity","type":"exact"},{"name":"protein-disulfide reductase activity","type":"broad"},{"name":"protein-disulphide reductase activity","type":"broad"}],"termid":"GO:0047134","terms_by_termid":{"GO:0004791":null,"GO:0047134":null}}


id: GO:0007288
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.","definition_xrefs":["ISBN:0198547684","GOC:bf","GOC:cilia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"is_a","term_name":"axoneme assembly","termid":"GO:0035082"},{"relation_name":"part_of","term_name":"sperm flagellum assembly","termid":"GO:0120316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0000226"}],"interesting_parent_ids":["GO:0044085","GO:0007010","GO:0008150","GO:0000226"],"is_obsolete":false,"name":"sperm axoneme assembly","termid":"GO:0007288"}


id: GO:1990295
data:
  {"annotated_genes":["SJAG_01297","SJAG_02336","SJAG_02695","SJAG_02045","SJAG_03073","SJAG_00930"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[103295,103646,108005],"is_not":false,"summary":null,"term":"GO:1990295"},{"annotations":[101184,96731],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1905759"},{"annotations":[91146],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1905760"}]},"cv_name":"cellular_component","definition":"A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center.","definition_xrefs":["PMID:11792817","PMID:9601091","PMID:17072892"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"microtubule cytoskeleton","termid":"GO:0015630"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00930":null,"SJAG_01297":null,"SJAG_02045":null,"SJAG_02336":null,"SJAG_02695":null,"SJAG_03073":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0015630","GO:0005575"],"is_obsolete":false,"name":"post-anaphase microtubule array","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"PAA","type":"exact"},{"name":"post-anaphase array","type":"exact"}],"termid":"GO:1990295","terms_by_termid":{"GO:1905759":null,"GO:1905760":null,"GO:1990295":null}}


id: PBO:0034481
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_level_during_cellular_response_to_hydroxyurea","termid":"PBO:0034481"}


id: MONDO:0010962
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic, isolated diffuse palmoplantar keratoderma characterized by diffuse, mild to thick, finely demarcated hyperkeratosis of palms and soles. Additional clinical findings include knuckle pad-like keratoses on fingers, hyperkeratosis of umbilicus and areolae, diffuse dry skin, hyperhidrosis, hangnails and frequent fungal infections. Histological examination of lesions reveals orthokeratotic hyperkeratosis, acanthosis, hypergranulosis, and mild lymphocyte infiltrations in the upper dermis with no evidence of epidermolysis.","definition_xrefs":["Orphanet:530838"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"diffuse palmoplantar keratoderma","termid":"MONDO:0017666"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0000426"],"is_obsolete":false,"name":"diffuse nonepidermolytic palmoplantar keratoderma","secondary_identifiers":["DOID:0070550","UMLS:C1833030","DOID:0050428","GARD:5186","Orphanet:496","OMIM:600962","SCTID:716105001","MEDGEN:371463"],"synonyms":[{"name":"KRT1-related diffuse nonepidermolytic keratoderma","type":"exact"},{"name":"NEPPK","type":"exact"},{"name":"PPK diffusa circumscripta","type":"related"},{"name":"PPKNE","type":"related"},{"name":"Thost-Unna disease","type":"related"},{"name":"Thost-Unna palmoplantar keratoderma","type":"related"},{"name":"Thost-Unna syndrome","type":"related"},{"name":"Unna-Thost palmoplantar keratoderma","type":"related"},{"name":"Unna-Thost syndrome","type":"related"},{"name":"autosomal dominant diffuse palmoplantar keratoderma, Norrbotten type","type":"narrow"},{"name":"diffuse NEPPK","type":"related"},{"name":"diffuse nonepidermolytic palmoplantar keratoderma","type":"exact"},{"name":"diffuse palmoplantar keratoderma, Bothnian type","type":"exact"},{"name":"keratoderma, nonepidermolytic palmoplantar","type":"related"},{"name":"non-epidermolytic palmoplantar keratoderma","type":"exact"},{"name":"nonepidermolytic palmoplantar keratoderma","type":"exact"},{"name":"palmoplantar keratoderma, nonepidermolytic","type":"exact"},{"name":"tylosis","type":"related"}],"termid":"MONDO:0010962","xrefs":{"Monarch":{"xref_id":"0010962"}}}


id: PBO:0034784
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone acetyltransferase complex PHD finger subunit Nto1 (predicted)","termid":"PBO:0034784"}


id: GO:0005987
data:
  {"annotated_genes":["SJAG_04301"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76452],"is_not":false,"summary":null,"term":"GO:0005987"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sucrose metabolic process","termid":"GO:0005985"},{"relation_name":"is_a","term_name":"disaccharide catabolic process","termid":"GO:0046352"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04301":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"sucrose catabolic process","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"sucrose breakdown","type":"exact"},{"name":"sucrose catabolism","type":"exact"},{"name":"sucrose degradation","type":"exact"}],"termid":"GO:0005987","terms_by_termid":{"GO:0005987":null}}


id: MONDO:0002129
data:
  {"annotated_genes":["SJAG_05979","SJAG_01349","SJAG_03453","SJAG_04287","SJAG_01748","SJAG_01013","SJAG_03905"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87132,86979,87131,86976,86978,86977],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0018874"},{"annotations":[85937],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0002629"}]},"cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm affecting the bone or articular cartilage.","definition_xrefs":["NCIT:C4016"],"direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system cancer","termid":"MONDO:0000637"},{"relation_name":"is_a","term_name":"bone neoplasm","termid":"MONDO:0019060"}],"gene_count":7,"genes_by_uniquename":{"SJAG_01013":null,"SJAG_01349":null,"SJAG_01748":null,"SJAG_03453":null,"SJAG_03905":null,"SJAG_04287":null,"SJAG_05979":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"bone cancer","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:D001859","SCTID:428281000","MEDGEN:79002","EFO:1000350","ICD9:170.9","DOID:184","UMLS:C0279530","CSP:2019-1041"],"synonyms":[{"name":"CA - bone cancer","type":"exact"},{"name":"bone cancer","type":"exact"},{"name":"bone neoplasm","type":"broad"},{"name":"bone tumor","type":"broad"},{"name":"bone tumour","type":"broad"},{"name":"cancer of bone","type":"exact"},{"name":"cancer of skeletal element","type":"exact"},{"name":"cancer of the bone","type":"exact"},{"name":"malignant bone neoplasm","type":"exact"},{"name":"malignant bone tumor","type":"exact"},{"name":"malignant bone tumour","type":"exact"},{"name":"malignant neoplasm of bone","type":"exact"},{"name":"malignant neoplasm of skeletal element","type":"exact"},{"name":"malignant neoplasm of the bone","type":"exact"},{"name":"malignant osseous neoplasm","type":"exact"},{"name":"malignant osseous tumor","type":"exact"},{"name":"malignant osseous tumour","type":"exact"},{"name":"malignant skeletal element neoplasm","type":"exact"},{"name":"malignant tumor of bone","type":"exact"},{"name":"malignant tumor of the bone","type":"exact"},{"name":"malignant tumour of bone","type":"exact"},{"name":"malignant tumour of the bone","type":"exact"},{"name":"osseous cancer","type":"exact"},{"name":"osseous tumor","type":"broad"},{"name":"osseous tumour","type":"broad"},{"name":"skeletal element cancer","type":"exact"}],"termid":"MONDO:0002129","terms_by_termid":{"MONDO:0002629":null,"MONDO:0018874":null},"xrefs":{"Monarch":{"xref_id":"0002129"}}}


id: GO:0048158
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.","definition_xrefs":["GOC:mtg_sensu","GOC:jid","ISBN:0198542771"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mammalian oogenesis stage","termid":"GO:0022605"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"oogonium stage","synonyms":[{"name":"mammalian oogenesis stage 1","type":"exact"}],"termid":"GO:0048158"}


id: PBO:0012033
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tandem fusion protein in S. cerevisiae, SPBC3H7.11 is related to the N-terminal region of YOR239W","termid":"PBO:0012033"}


id: GO:0010508
data:
  {"annotated_genes":["SJAG_05289","SJAG_05346","SJAG_00704","SJAG_03851","SJAG_02433","SJAG_00169","SJAG_04249","SJAG_04502","SJAG_00824","SJAG_04496","SJAG_01716","SJAG_01184","SJAG_04435","SJAG_02765","SJAG_05000"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73362,73389,79724,98636,99205,109424,111589,114325],"is_not":false,"summary":null,"term":"GO:0010508"},{"annotations":[108319,108409],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000786"},{"annotations":[97379],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901098"},{"annotations":[68697],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903599"},{"annotations":[106019,75085],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016239"},{"annotations":[89281],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140501"}]},"cv_name":"biological_process","definition":"Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of catabolic process","termid":"GO:0009896"},{"relation_name":"is_a","term_name":"regulation of autophagy","termid":"GO:0010506"},{"relation_name":"positively_regulates","term_name":"autophagy","termid":"GO:0006914"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00169":null,"SJAG_00704":null,"SJAG_00824":null,"SJAG_01184":null,"SJAG_01716":null,"SJAG_02433":null,"SJAG_02765":null,"SJAG_03851":null,"SJAG_04249":null,"SJAG_04435":null,"SJAG_04496":null,"SJAG_04502":null,"SJAG_05000":null,"SJAG_05289":null,"SJAG_05346":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006914"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006914"}],"interesting_parent_ids":["GO:0006914","GO:0008150"],"is_obsolete":false,"name":"positive regulation of autophagy","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"termid":"GO:0010508","terms_by_termid":{"GO:0010508":null,"GO:0016239":null,"GO:0140501":null,"GO:1901098":null,"GO:1903599":null,"GO:2000786":null}}


id: PBO:0034553
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_transcription_from_CRE_promoter","termid":"PBO:0034553"}


id: PBO:0053801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1056","termid":"PBO:0053801"}


id: MONDO:0024542
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any dysequilibrium syndrome in which the cause of the disease is a mutation in the VLDLR gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebellar ataxia, intellectual disability, and dysequilibrium","termid":"MONDO:0009133"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005559"],"is_obsolete":false,"name":"cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 1","secondary_identifiers":["DOID:0070556","MEDGEN:1639436","UMLS:C4551552","OMIM:224050"],"synonyms":[{"name":"CAMRQ1","type":"related"},{"name":"VLDLR dysequilibrium syndrome","type":"exact"},{"name":"cerebellar ataxia and intellectual disability with or without quadrupedal locomotion 1","type":"related"},{"name":"cerebellar ataxia and mental retardation with or without quadrupedal locomotion 1","type":"related"},{"name":"cerebellar ataxia, congenital, and intellectual disability, autosomal recessive","type":"related"},{"name":"cerebellar ataxia, congenital, and mental retardation, autosomal recessive","type":"related"},{"name":"cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 1","type":"exact"},{"name":"cerebellar ataxia, intellectual disability, and dysequilibrium syndrome type 1","type":"exact"},{"name":"cerebellar ataxia, mental retardation, and dysequilibrium syndrome 1","type":"related"},{"name":"cerebellar ataxia, mental retardation, and dysequilibrium syndrome type 1","type":"exact"},{"name":"cerebellar hypoplasia and mental retardation with or without quadrupedal locomotion 1","type":"exact"},{"name":"cerebellar hypoplasia, VLDLR-associated","type":"related"},{"name":"dysequilibrium syndrome","type":"related"},{"name":"dysequilibrium syndrome caused by mutation in VLDLR","type":"exact"}],"termid":"MONDO:0024542","xrefs":{"Monarch":{"xref_id":"0024542"}}}


id: GO:0046128
data:
  {"annotated_genes":["SJAG_02959","SJAG_01070","SJAG_06634","SJAG_00044","SJAG_03096","SJAG_02580","SJAG_01859","SJAG_00134","SJAG_03881","SJAG_02582"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88641],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046086"},{"annotations":[87346,87347],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006154"},{"annotations":[90309],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046085"},{"annotations":[116579],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006169"},{"annotations":[69687],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006190"},{"annotations":[93520,73297,61722,66396],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006166"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribonucleoside metabolic process","termid":"GO:0009119"},{"relation_name":"is_a","term_name":"purine nucleoside metabolic process","termid":"GO:0042278"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00044":null,"SJAG_00134":null,"SJAG_01070":null,"SJAG_01859":null,"SJAG_02580":null,"SJAG_02582":null,"SJAG_02959":null,"SJAG_03096":null,"SJAG_03881":null,"SJAG_06634":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0055086","GO:0008150"],"is_obsolete":false,"name":"purine ribonucleoside metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000043":null,"GO_REF:0000107":null},"synonyms":[{"name":"purine ribonucleoside metabolism","type":"exact"}],"termid":"GO:0046128","terms_by_termid":{"GO:0006154":null,"GO:0006166":null,"GO:0006169":null,"GO:0006190":null,"GO:0046085":null,"GO:0046086":null}}


id: PBO:0046877
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 8 member A2, pseudogene","termid":"PBO:0046877"}


id: PBO:0004203
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ski complex subunit Rec14","termid":"PBO:0004203"}


id: PBO:0073527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SH3 domain containing GRB2 like 1, endophilin A2","termid":"PBO:0073527"}


id: PBO:0085372
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pH sensor molecule, component of the RIM101 pathway; has a role in cell wall construction and alkaline pH response; is glycosylated and phosphorylated; interacts with Dfg16p and Rim9p to form a pH-sensing complex; localization to the plasma membrane is dependent on Dfg16p and Rim9p; has similarity to A. nidulans PalH","termid":"PBO:0085372"}


id: MONDO:0011383
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, primary immunodeficiency with an autosomal dominant pattern of inheritance but incomplete penetrance. It is caused by a mutation in the CASP10 (caspase-10) gene that leads to defective Fas-induced apoptosis. Disruption of Fas-induced apoptosis impairs lymphocyte homeostasis and immune tolerance. Characteristic laboratory findings include an increase in circulating, double-negative (CD4-/CD8-) T cells in the setting of immune-mediated anemia, thrombocytopenia and neutropenia. Clinical signs present in childhood include fatigue, pallor, bruising, hepatosplenomegaly and chronic, non-malignant, non-infectious lymphadenopathy. The clinical course is influenced by a strong association with other autoimmune disorders and an increased risk for developing Hodgkin and non-Hodgkin lymphoma.","definition_xrefs":["NCIT:C39576"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune lymphoproliferative syndrome","termid":"MONDO:0017979"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"autoimmune lymphoproliferative syndrome type 2A","secondary_identifiers":["DOID:0110115","GARD:15361","MESH:C565833","UMLS:C1858968","MEDGEN:349065","OMIM:603909"],"synonyms":[{"name":"ALPS-CASP10","type":"exact"},{"name":"ALPS2A","type":"exact"},{"name":"CASP10 autoimmune lymphoproliferative syndrome","type":"exact"},{"name":"autoimmune lymphoproliferative syndrome caused by mutation in CASP10","type":"exact"},{"name":"autoimmune lymphoproliferative syndrome type IIA","type":"exact"},{"name":"autoimmune lymphoproliferative syndrome, type 2","type":"related"},{"name":"autoimmune lymphoproliferative syndrome, type 2A","type":"related"},{"name":"autoimmune lymphoproliferative syndrome, type II","type":"exact"},{"name":"autoimmune lymphoproliferative syndrome, type IIA","type":"related"},{"name":"autoimmune lymphoproliferative syndrome-CASP10 variant","type":"exact"},{"name":"type 2 ALPS","type":"exact"},{"name":"type 2 autoimmune lymphoproliferative syndrome","type":"exact"}],"termid":"MONDO:0011383","xrefs":{"Monarch":{"xref_id":"0011383"}}}


id: PBO:0001410
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor Pap1/Caf3","termid":"PBO:0001410"}


id: PBO:0028471
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-altered_cytochrome_absorption_spectrum","termid":"PBO:0028471"}


id: PBO:0112692
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome-b5 reductase activity/ NAD(P)H-dependent reductase for Dph3, Cbr1","termid":"PBO:0112692"}


id: FYPO:0007411
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of residues within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II is abnormal, resulting in an abnormal distribution of RNA polymerase II molecules with different C-terminal domain residue phosphorylation patterns.","definition_xrefs":["PMID:32499400","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal RNA polymerase II C-terminal domain phosphorylation","termid":"FYPO:0007410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0002274","FYPO:0002494","FYPO:0000002"],"is_obsolete":false,"name":"abnormal distribution of RNA polymerase II C-terminal domain residue phosphorylation during vegetative growth","synonyms":[{"name":"abnormal distribution of RNA polymerase II C-terminal domain residue phosphorylation during mitotic cell cycle","type":"related"}],"termid":"FYPO:0007411"}


id: PBO:0034547
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_RNA_localization_to_nucleus","termid":"PBO:0034547"}


id: MONDO:0003724
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Breast fibrocystic change characterized by the absence of epithelial cell hyperplasia.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"breast fibrocystic disease","termid":"MONDO:0005219"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-proliferative fibrocystic change of the breast","secondary_identifiers":["MEDGEN:231966","DOID:5997","UMLS:C1332628","NCIT:C6943"],"synonyms":[{"name":"breast fibrocystic change, non-proliferative type","type":"exact"},{"name":"non-proliferative fibrocystic change","type":"exact"},{"name":"non-proliferative fibrocystic change of breast","type":"exact"}],"termid":"MONDO:0003724","xrefs":{"Monarch":{"xref_id":"0003724"}}}


id: GO:0007020
data:
  {"annotated_genes":["SJAG_02609","SJAG_03835","SJAG_02737","SJAG_01756","SJAG_01215","SJAG_07018","SJAG_02886","SJAG_00856","SJAG_02761","SJAG_03540"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70911,71428,78732],"is_not":false,"summary":null,"term":"GO:0007020"},{"annotations":[116682],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030954"},{"annotations":[100140,99843,106205,116687,116933,100743],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051415"},{"annotations":[118404,100744],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051417"}]},"cv_name":"biological_process","definition":"The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).","definition_xrefs":["GOC:go_curators","ISBN:0815316194","PMID:12517712"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule cytoskeleton organization","termid":"GO:0000226"},{"relation_name":"part_of","term_name":"microtubule polymerization","termid":"GO:0046785"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00856":null,"SJAG_01215":null,"SJAG_01756":null,"SJAG_02609":null,"SJAG_02737":null,"SJAG_02761":null,"SJAG_02886":null,"SJAG_03540":null,"SJAG_03835":null,"SJAG_07018":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0000226"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0000226"}],"interesting_parent_ids":["GO:0000226","GO:0065003","GO:0007010","GO:0008150","GO:0044085"],"is_obsolete":false,"name":"microtubule nucleation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Wikipedia:Microtubule_nucleation"],"termid":"GO:0007020","terms_by_termid":{"GO:0007020":null,"GO:0030954":null,"GO:0051415":null,"GO:0051417":null}}


id: MONDO:0007352
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Renal coloboma syndrome (RCS) is a genetic condition characterized by optic nerve dysplasia and renal hypodysplasia.","definition_xrefs":["Orphanet:1475"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"renal coloboma syndrome","secondary_identifiers":["UMLS:C1852759","NCIT:C123230","ICD10CM:Q60.4","ICD9:759.89","SCTID:446449009","MEDGEN:339002","MESH:C537168","DOID:0090006","GARD:4106","OMIM:120330"],"synonyms":[{"name":"CAKUT with or without ocular abnormalities","type":"exact"},{"name":"PAPILLORENAL syndrome","type":"related"},{"name":"PAPRS","type":"related"},{"name":"Papillo-renal syndrome","type":"exact"},{"name":"coloboma of optic nerve with renal disease","type":"exact"},{"name":"congenital anomalies of the kidney and urinary tract with or without ocular abnormalities","type":"exact"},{"name":"optic coloboma, vesicoureteral reflux and renal anomalies","type":"exact"},{"name":"optic coloboma, vesicoureteral reflux, and renal anomalies","type":"related"},{"name":"optic nerve coloboma with renal disease","type":"related"},{"name":"papillo-renal syndrome, optic nerve coloboma with renal disease","type":"exact"},{"name":"papillorenal syndrome","type":"exact"},{"name":"renal-coloboma syndrome","type":"related"},{"name":"renal-coloboma syndrome with macular abnormalities","type":"exact"}],"termid":"MONDO:0007352","xrefs":{"Monarch":{"xref_id":"0007352"}}}


id: GO:0009408
data:
  {"annotated_genes":["SJAG_03815","SJAG_03527","SJAG_02266","SJAG_04055","SJAG_04567","SJAG_02381","SJAG_04082","SJAG_04187","SJAG_03949","SJAG_02426","SJAG_03319","SJAG_00436","SJAG_01186","SJAG_04388","SJAG_01584"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104074,78761],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070370"},{"annotations":[115240,88601,91849,115241,100294,109755,95447,96236,104757,105041,109754,90574],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034605"},{"annotations":[72956],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031990"}]},"cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to stress","termid":"GO:0006950"},{"relation_name":"is_a","term_name":"response to temperature stimulus","termid":"GO:0009266"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00436":null,"SJAG_01186":null,"SJAG_01584":null,"SJAG_02266":null,"SJAG_02381":null,"SJAG_02426":null,"SJAG_03319":null,"SJAG_03527":null,"SJAG_03815":null,"SJAG_03949":null,"SJAG_04055":null,"SJAG_04082":null,"SJAG_04187":null,"SJAG_04388":null,"SJAG_04567":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to heat","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0006951"],"synonyms":[{"name":"response to heat shock","type":"narrow"}],"termid":"GO:0009408","terms_by_termid":{"GO:0031990":null,"GO:0034605":null,"GO:0070370":null}}


id: PBO:0064920
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PPP4R3B divergent transcript","termid":"PBO:0064920"}


id: MONDO:0021400
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A polyp that involves the colon.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colonic disorder","termid":"MONDO:0003409"},{"relation_name":"is_a","term_name":"polyp of large intestine","termid":"MONDO:0021392"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"polyp of colon","secondary_identifiers":["NCIT:C2954","SCTID:68496003","MEDGEN:3166","ICD10CM:K63.5","UMLS:C0009376","MESH:D003111"],"synonyms":[{"name":"colon polyp","type":"exact"},{"name":"colonic polyp","type":"exact"},{"name":"polyp of the colon","type":"exact"}],"termid":"MONDO:0021400","xrefs":{"Monarch":{"xref_id":"0021400"}}}


id: PBO:0029434
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_curved_septated_vegetative_cell","termid":"PBO:0029434"}


id: MONDO:0859358
data:
  {"annotated_genes":["SJAG_01240"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85327],"is_not":false,"summary":null,"term":"MONDO:0859358"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated dilated cardiomyopathy","termid":"MONDO:0700335"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01240":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cardiomyopathy, dilated, 2H","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:620203","MEDGEN:1824069","UMLS:C5774296"],"termid":"MONDO:0859358","terms_by_termid":{"MONDO:0859358":null},"xrefs":{"Monarch":{"xref_id":"0859358"}}}


id: PBO:0083372
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection, though phenotype could be due to the mutation's effects on BUD7","termid":"PBO:0083372"}


id: PBO:0001819
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.1.2.3","termid":"PBO:0001819"}


id: GO:0009471
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete class III cytochrome c (obsolete GO:0009471)","synonyms":[{"name":"class III cytochrome c","type":"exact"}],"termid":"GO:0009471"}


id: GO:0016259
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.","definition_xrefs":["GOC:go_curators","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"serine family amino acid metabolic process","termid":"GO:0009069"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"selenocysteine metabolic process","secondary_identifiers":["Reactome:R-HSA-2408522"],"synonyms":[{"name":"selenocysteine metabolism","type":"exact"}],"termid":"GO:0016259"}


id: PBO:0111841
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RWD domain","termid":"PBO:0111841"}


id: MONDO:0019641
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pauci-immune glomerulonephritis (GN) is one of the most frequent causes of rapidly progressive GN (RPGN). It is characterized clinically by renal manifestations of RPGN (hematuria, hypertension) leading to renal failure within days or weeks, and may be associated with manifestations of systemic vasculitis (arthralgia, fever, seizures, mono neuritis and lung involvement). Pauci-immune GN is histologically characterized by focal necrotizing and crescentic GN, with mild or absent glomerular staining for immunoglobulin and complement by fluorescence microscopy, which may manifest either as part of a systemic small vessel vasculitis (including microscopic polyangiitis, granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis), or rarely as part of renal-limited vasculitis (RLV, idiopathic crescentic GN). Immunologic classification is based on the presence or absence of circulating anti-neutrophil cytoplasmic antibodies (ANCAs), namely pauci-immune-GN with ANCA and pauci-immune GN without ANCA.","definition_xrefs":["Orphanet:93126"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete secondary glomerular disease (obsolete MONDO:0019724)","termid":"MONDO:0019724"},{"relation_name":"is_a","term_name":"glomerulonephritis","termid":"MONDO:0002462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"Pauci-immune glomerulonephritis","secondary_identifiers":["MEDGEN:575439","UMLS:C0343196","GARD:19175","icd11.foundation:1359757645"],"termid":"MONDO:0019641","xrefs":{"Monarch":{"xref_id":"0019641"}}}


id: MONDO:1012095
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hemolytic anemia, non-human animal","termid":"MONDO:1011689"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hemolytic anemia, dog","secondary_identifiers":["OMIA:000430-9615"],"termid":"MONDO:1012095","xrefs":{"Monarch":{"xref_id":"1012095"}}}


id: FYPO:0005530
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the IRC1L boundary element is abolished.","definition_xrefs":["PomBase:mah","PMID:25972440"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to chromatin during vegetative growth","termid":"FYPO:0000452"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"abolished protein localization to chromatin at boundary element IRC1L","synonyms":[{"name":"abolished protein localisation to chromatin at boundary element IRC1L during vegetative growth","type":"exact"},{"name":"abolished protein localization to centromeric boundary element IRC1L","type":"exact"},{"name":"abolished protein localization to chromatin at boundary element IRC1L during mitotic cell cycle","type":"related"},{"name":"protein localization to chromatin at boundary element IRC1L during vegetative growth abolished","type":"exact"}],"termid":"FYPO:0005530"}


id: PBO:0062317
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 6 subfamily B member 2","termid":"PBO:0062317"}


id: PBO:0069967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1262, pseudogene","termid":"PBO:0069967"}


id: PBO:0083672
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Endoplasmic reticulum zinc transporter; part of a heterodimeric transporter with Msc2p that transfers zinc from the cytosol to the ER lumen; member of the cation diffusion facilitator family of efflux pumps; zinc-regulated directly through Zap1p; transcription induced under conditions of zinc deficiency","termid":"PBO:0083672"}


id: PBO:0043570
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type VII alpha 1 chain","termid":"PBO:0043570"}


id: GO:0021665
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.","definition_xrefs":["GOC:dph","GOC:jid","GO_REF:0000021","GOC:dgh","GOC:cls"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rhombomere structural organization","termid":"GO:0021595"},{"relation_name":"part_of","term_name":"rhombomere 5 morphogenesis","termid":"GO:0021664"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"rhombomere 5 structural organization","synonyms":[{"name":"rhombomere 5 structural organisation","type":"exact"}],"termid":"GO:0021665"}


id: MONDO:0013701
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete MRT32 (obsolete MONDO:0013701)","secondary_identifiers":["OMIM:614339"],"termid":"MONDO:0013701","xrefs":{"Monarch":{"xref_id":"0013701"}}}


id: PBO:0040496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AUP1 lipid droplet regulating VLDL assembly factor","termid":"PBO:0040496"}


id: PR:Q9UT09
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAP8A3.07c gene.","definition_xrefs":["UniProtKB:Q9UT09","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAP8A3.07c","synonyms":[{"name":"3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"DAHP synthase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-SPAP8A3.07c","type":"exact"},{"name":"phospho-2-keto-3-deoxyheptonate aldolase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UT09"}


id: FYPO:0006511
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which cells form telomeres that are shorter than normal during G0 phase. Normally, telomere length is stable in G0, whereas telomere sequences can be lost in mutants.","definition_xrefs":["PMID:29167439","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal telomere length","termid":"FYPO:0006509"},{"relation_name":"is_a","term_name":"abnormal telomere morphology during G0","termid":"FYPO:0007413"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000641"},{"rel_name":"output_of","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000293","FYPO:0001985","FYPO:0000641","FYPO:0000002"],"is_obsolete":false,"name":"shortened telomeres during G0","synonyms":[{"name":"decreased telomere length during G0","type":"related"},{"name":"loss of telomeric sequence during G0","type":"exact"},{"name":"loss of telomeric sequence during quiescence","type":"exact"},{"name":"reduced telomere length during G0","type":"exact"},{"name":"short telomeres during G0","type":"exact"},{"name":"shortened telomeres during cell quiescence","type":"exact"},{"name":"shortened telomeres during quiescence","type":"exact"}],"termid":"FYPO:0006511"}


id: PBO:0081568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 493","termid":"PBO:0081568"}


id: MOD:01299
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification produced by formation of an adduct of an L-histidine residue with 4-hydroxynonenal artificially reduced by a reagent such as NaBH4.","definition_xrefs":["Unimod:335#K","PubMed:12148805","PubMed:11910026","PubMed:15133838"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"lysine 4-hydroxynonenal adduct","termid":"MOD:01238"},{"relation_name":"is_a","term_name":"reduced 4-hydroxynonenal adduct","termid":"MOD:00642"},{"relation_name":"is_a","term_name":"modified L-lysine residue","termid":"MOD:00912"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:01155"}],"interesting_parent_ids":["MOD:01155"],"is_obsolete":false,"name":"reduced lysine 4-hydroxynonenal adduct","synonyms":[{"name":"HNE+Delta:H(2)","type":"related"},{"name":"reduced 4-Hydroxynonenal","type":"related"}],"termid":"MOD:01299"}


id: PBO:0091879
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER sterol deacetylase Say1","termid":"PBO:0091879"}


id: GO:2000539
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein geranylgeranylation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of macromolecule biosynthetic process","termid":"GO:0010556"},{"relation_name":"is_a","term_name":"regulation of protein modification process","termid":"GO:0031399"},{"relation_name":"regulates","term_name":"protein geranylgeranylation","termid":"GO:0018344"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of protein geranylgeranylation","synonyms":[{"name":"regulation of C-terminal protein geranylgeranylation","type":"related"},{"name":"regulation of protein amino acid geranylgeranylation","type":"exact"}],"termid":"GO:2000539"}


id: PBO:0073316
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine hydrolase like (pseudogene)","termid":"PBO:0073316"}


id: GO:1902299
data:
  {"annotated_genes":["SJAG_00247","SJAG_02074","SJAG_02607"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[114766,103074,110311],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902985"}]},"cv_name":"biological_process","definition":"Any pre-replicative complex assembly that is involved in cell cycle DNA replication.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle process","termid":"GO:0022402"},{"relation_name":"is_a","term_name":"pre-replicative complex assembly","termid":"GO:0036388"},{"relation_name":"part_of","term_name":"cell cycle DNA replication","termid":"GO:0044786"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00247":null,"SJAG_02074":null,"SJAG_02607":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0006260"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0006260","GO:0007049","GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"pre-replicative complex assembly involved in cell cycle DNA replication","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"pre-RC assembly involved in cell cycle DNA replication","type":"exact"},{"name":"pre-replication complex assembly involved in cell cycle DNA replication","type":"related"}],"termid":"GO:1902299","terms_by_termid":{"GO:1902985":null}}


id: MONDO:0100498
data:
  {"annotated_genes":["SJAG_04109"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85489],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008296"}]},"cv_name":"mondo","definition":"Any inherited porphyria in which the cause of the disease is monoallelic or biallelic variants in the UROD gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited porphyria","termid":"MONDO:0019142"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04109":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0019142"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066","MONDO:0019142"],"is_obsolete":false,"name":"UROD-related inherited porphyria","references_by_uniquename":{"PB_REF:0000006":null},"termid":"MONDO:0100498","terms_by_termid":{"MONDO:0008296":null},"xrefs":{"Monarch":{"xref_id":"0100498"}}}


id: PBO:0000623
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zf-CCHC type (zinc knuckle)","termid":"PBO:0000623"}


id: FYPO:0002038
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deadenylation-independent decapping of nuclear-transcribed mRNA is abnormal. This decapping process is cleavage of the 5'-cap of a nuclear-transcribed mRNA, independent of poly(A) tail shortening. All RNA decapping may be abnormal, or one or more specific RNA molecules may be selectively affected.","definition_xrefs":["PomBase:mah","GO:0031087"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal RNA catabolic process during vegetative growth","termid":"FYPO:0002136"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000294"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0000294"],"is_obsolete":false,"name":"abnormal deadenylation-independent decapping of nuclear-transcribed mRNA","synonyms":[{"name":"abnormal deadenylation-independent decapping of nuclear-transcribed mRNA during mitotic cell cycle","type":"related"},{"name":"abnormal deadenylation-independent decapping of nuclear-transcribed mRNA during vegetative growth","type":"exact"}],"termid":"FYPO:0002038"}


id: GO:0034329
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component assembly","termid":"GO:0022607"},{"relation_name":"is_a","term_name":"cell junction organization","termid":"GO:0034330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"cell junction assembly","secondary_identifiers":["Reactome:R-HSA-446728"],"termid":"GO:0034329"}


id: PBO:0044392
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 2 subfamily C member 9","termid":"PBO:0044392"}


id: GO:0036215
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.","definition_xrefs":["GOC:uh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to cytokine","termid":"GO:0034097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to stem cell factor","synonyms":[{"name":"response to KIT ligand","type":"exact"},{"name":"response to SCF","type":"exact"},{"name":"response to hematopoietic growth factor KL","type":"exact"},{"name":"response to stem cell factor stimulus","type":"exact"}],"termid":"GO:0036215"}


id: GO:0004825
data:
  {"annotated_genes":["SJAG_01159","SJAG_16456"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[69161,77938],"is_not":false,"summary":null,"term":"GO:0004825"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).","definition_xrefs":["EC:6.1.1.10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoacyl-tRNA ligase activity","termid":"GO:0004812"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01159":null,"SJAG_16456":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140101","GO:0003824","GO:0003674","GO:0016874","GO:0140098"],"is_obsolete":false,"name":"methionine-tRNA ligase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-379994","MetaCyc:METHIONINE--TRNA-LIGASE-RXN","Reactome:R-HSA-380157","RHEA:13481"],"synonyms":[{"name":"L-methionine:tRNAMet ligase (AMP-forming)","type":"related"},{"name":"MetRS activity","type":"related"},{"name":"methionine translase activity","type":"related"},{"name":"methionyl-tRNA synthetase activity","type":"exact"},{"name":"methionyl-transfer RNA synthetase activity","type":"related"},{"name":"methionyl-transfer ribonucleate synthetase activity","type":"related"},{"name":"methionyl-transfer ribonucleic acid synthetase activity","type":"related"}],"termid":"GO:0004825","terms_by_termid":{"GO:0004825":null}}


id: PR:O42978
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A U6 snRNA-associated Sm-like protein LSm5 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03650","PANTHER:PTHR20971:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U6 snRNA-associated Sm-like protein LSm5 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC20F10.09","secondary_identifiers":["UniProtKB:O42978"],"synonyms":[{"name":"Spom972h-LSM5","type":"exact"}],"termid":"PR:O42978"}


id: FYPO:0006011
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which mating projection assembly occurs along the lateral portion of the long axis of the cell instead of at one cell end.","definition_xrefs":["PMID:28410370","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal shmoo formation","termid":"FYPO:0000568"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000301"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0000301","FYPO:0005447"],"is_obsolete":false,"name":"shmoo formation at cell side","synonyms":[{"name":"lateral shmoo formation","type":"exact"},{"name":"mating projection assembly at cell side","type":"exact"},{"name":"shmoo formation on cell side","type":"exact"}],"termid":"FYPO:0006011"}


id: PBO:0081856
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 789","termid":"PBO:0081856"}


id: PBO:0000950
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial DDHD family phospholipase (predicted)","termid":"PBO:0000950"}


id: PBO:0086858
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative RNA exonuclease; possibly involved in pre-rRNA processing and ribosome assembly","termid":"PBO:0086858"}


id: MONDO:1010516
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Jacobsen syndrome that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Jacobsen syndrome, non-human animal","termid":"MONDO:1010032"},{"relation_name":"is_a","term_name":"thrombocytopenia, cattle","termid":"MONDO:1010662"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Jacobsen syndrome, cattle","secondary_identifiers":["OMIA:002558-9913"],"termid":"MONDO:1010516","xrefs":{"Monarch":{"xref_id":"1010516"}}}


id: PBO:0091025
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane pantothenate transmembrane transporter Liz1","termid":"PBO:0091025"}


id: GO:0046014
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of T cell proliferation","termid":"GO:0042130"},{"relation_name":"is_a","term_name":"regulation of T cell homeostatic proliferation","termid":"GO:0046013"},{"relation_name":"negatively_regulates","term_name":"T cell homeostatic proliferation","termid":"GO:0001777"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0007155"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"negative regulation of T cell homeostatic proliferation","synonyms":[{"name":"down regulation of T cell homeostatic proliferation","type":"exact"},{"name":"down-regulation of T cell homeostatic proliferation","type":"exact"},{"name":"downregulation of T cell homeostatic proliferation","type":"exact"},{"name":"inhibition of T cell homeostatic proliferation","type":"narrow"},{"name":"negative regulation of T lymphocyte homeostatic proliferation","type":"exact"},{"name":"negative regulation of T-cell homeostatic proliferation","type":"exact"},{"name":"negative regulation of T-lymphocyte homeostatic proliferation","type":"exact"},{"name":"negative regulation of resting T cell proliferation","type":"exact"}],"termid":"GO:0046014"}


id: GO:0019686
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.","definition_xrefs":["ISBN:0306444747","ISBN:0471394831","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleobase-containing small molecule interconversion","termid":"GO:0015949"},{"relation_name":"is_a","term_name":"purine nucleoside metabolic process","termid":"GO:0042278"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0055086","GO:0008150"],"is_obsolete":false,"name":"purine nucleoside interconversion","termid":"GO:0019686"}


id: GO:0097423
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans.","definition_xrefs":["NIF_Subcellular:sao1933817066","PMID:20089910"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"mitochondrion-associated adherens complex","synonyms":[{"name":"MAC","type":"related"},{"name":"mitochondrial adhaerens complex","type":"exact"}],"termid":"GO:0097423"}


id: GO:0070595
data:
  {"annotated_genes":["SJAG_04184","SJAG_02278","SJAG_03057","SJAG_02916","SJAG_01028","SJAG_04236","SJAG_04666","SJAG_00424","SJAG_00610"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71274,73168,70325,73030,78464],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070600"},{"annotations":[92190,89199,94698,102599],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0070610"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-glucan metabolic process","termid":"GO:0030978"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00424":null,"SJAG_00610":null,"SJAG_01028":null,"SJAG_02278":null,"SJAG_02916":null,"SJAG_03057":null,"SJAG_04184":null,"SJAG_04236":null,"SJAG_04666":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"(1->3)-alpha-glucan metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"1,3-alpha-glucan metabolic process","type":"exact"},{"name":"1,3-alpha-glucan metabolism","type":"exact"},{"name":"alpha-1,3 glucan metabolic process","type":"exact"},{"name":"alpha-1,3 glucan metabolism","type":"exact"}],"termid":"GO:0070595","terms_by_termid":{"GO:0070600":null,"GO:0070610":null}}


id: PBO:0068148
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 455","termid":"PBO:0068148"}


id: PBO:0067674
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 856, pseudogene","termid":"PBO:0067674"}


id: GO:0052571
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete response to symbiont immune response (obsolete GO:0052571)","synonyms":[{"name":"response to symbiont immune response","type":"exact"}],"termid":"GO:0052571"}


id: PBO:0084297
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Intraperoxisomal organizer of the peroxisomal import machinery; organizes the formation of the importomer complex, bridging the docking complex with the RING finger complex; tightly associated with the lumenal face of the peroxisomal membrane; essential for peroxisome biogenesis; binds PTS1-signal receptor Pex5p, and PTS2-signal receptor Pex7p","termid":"PBO:0084297"}


id: PBO:0056501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methyl-CpG binding domain protein 3 like 5","termid":"PBO:0056501"}


id: PBO:0074806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 13 pseudogene 1","termid":"PBO:0074806"}


id: PBO:0001858
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1,3-beta-glucan synthase subunit Bgs2","termid":"PBO:0001858"}


id: PBO:0001822
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"40S ribosomal protein S11 (predicted)","termid":"PBO:0001822"}


id: PBO:0069930
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1223, pseudogene","termid":"PBO:0069930"}


id: PBO:0083916
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Formin; polarisome component; nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables; recruited to the division site in a Glc7p/Ref2p dependent manner following release of Bnr1p; functionally redundant with BNR1","termid":"PBO:0083916"}


id: PBO:0012567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome complex subunit beta 2 (predicted)","termid":"PBO:0012567"}


id: GO:0017009
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.","definition_xrefs":["RESID:AA0131"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-bilin linkage","termid":"GO:0017007"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein-phycocyanobilin linkage","termid":"GO:0017009"}


id: PBO:0049773
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HLA complex group 9","termid":"PBO:0049773"}


id: GO:0048007
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.","definition_xrefs":["GOC:add","PMID:10375559","PMID:15928678","PMID:15928680"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antigen processing and presentation of exogenous antigen","termid":"GO:0019884"},{"relation_name":"is_a","term_name":"antigen processing and presentation of lipid antigen via MHC class Ib","termid":"GO:0048003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"antigen processing and presentation, exogenous lipid antigen via MHC class Ib","synonyms":[{"name":"antigen presentation, exogenous peptide antigen","type":"exact"},{"name":"exogenous lipid antigen processing and presentation via MHC class Ib","type":"exact"}],"termid":"GO:0048007"}


id: PBO:0048121
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fucosyltransferase 2","termid":"PBO:0048121"}


id: PBO:0080823
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"xylosyltransferase 1","termid":"PBO:0080823"}


id: PBO:0069258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 513, pseudogene","termid":"PBO:0069258"}


id: GO:0047845
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: deoxylimonoate + H2O = deoxylimononate D-ring-lactone + H+.","definition_xrefs":["EC:3.1.1.46","RHEA:14997"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016788","GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"deoxylimonate A-ring-lactonase activity","secondary_identifiers":["KEGG_REACTION:R03803","MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN"],"synonyms":[{"name":"deoxylimonate A-ring-lactonohydrolase activity","type":"related"}],"termid":"GO:0047845"}


id: MOD:01793
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-cysteine residue to S-carboxamidomethyl-L-cysteine sulfoxide.","definition_xrefs":["PubMed:18306178","PubMed:18688235","PubMed:17689096","PubMed:11212008"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"S-carboxamidomethyl-L-cysteine","termid":"MOD:01060"},{"relation_name":"is_a","term_name":"iodoacetamide derivatized residue","termid":"MOD:00397"},{"relation_name":"is_a","term_name":"sulfur oxygenated L-cysteine","termid":"MOD:00708"},{"relation_name":"is_a","term_name":"sulfur monooxygenated residue","termid":"MOD:01854"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"S-carboxamidomethyl-L-cysteine sulfoxide","synonyms":[{"name":"CamCO","type":"exact"},{"name":"S-carbamoylmethyl-L-cysteine sulfoxide","type":"exact"}],"termid":"MOD:01793"}


id: GO:0070413
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.","definition_xrefs":["PMID:9797333","GOC:jp","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete trehalose metabolism in response to stress (obsolete GO:0070413)","synonyms":[{"name":"trehalose metabolic process involved in response to stress","type":"exact"}],"termid":"GO:0070413"}


id: MONDO:0009685
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A distal myopathy, characterized by weakness in the distal lower extremity posterior compartment (gastrocnemius and soleus muscles) and associated with difficulties in standing on tip toes.","definition_xrefs":["Orphanet:45448"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"qualitative or quantitative defects of dysferlin","termid":"MONDO:0016145"},{"relation_name":"is_a","term_name":"distal myopathy","termid":"MONDO:0018949"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"Miyoshi myopathy","secondary_identifiers":["UMLS:C5553104","MEDGEN:1790866","NANDO:1200217","GARD:9676","NCIT:C118846","DOID:0070198","OMIMPS:254130","MESH:C537480"],"synonyms":[{"name":"MM","type":"exact"},{"name":"MMD1","type":"narrow"},{"name":"Miyoshi distal myopathy","type":"exact"},{"name":"Miyoshi muscular dystrophy","type":"exact"},{"name":"Miyoshi muscular dystrophy 1","type":"narrow"},{"name":"Miyoshi muscular dystrophy type 1","type":"narrow"},{"name":"muscular dystrophy, distal, late onset, autosomal recessive","type":"related"}],"termid":"MONDO:0009685","xrefs":{"Monarch":{"xref_id":"0009685"}}}


id: MONDO:0002925
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete extraosseous Ewing's sarcoma (obsolete MONDO:0002925)","termid":"MONDO:0002925","xrefs":{"Monarch":{"xref_id":"0002925"}}}


id: SO:0000515
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"7 nucleotide recombination site (e.g. CACAGTG), part of a J-gene recombination feature of an immunoglobulin/T-cell receptor gene.","direct_ancestors":[{"relation_name":"is_a","term_name":"heptamer_of_recombination_feature_of_vertebrate_immune_system_gene","termid":"SO:0000561"},{"relation_name":"part_of","term_name":"J_gene_recombination_feature","termid":"SO:0000302"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"J_heptamer","synonyms":[{"name":"J heptamer","type":"exact"},{"name":"J-HEPTAMER","type":"exact"}],"termid":"SO:0000515"}


id: MONDO:0060627
data:
  {"annotated_genes":["SJAG_03292"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84856],"is_not":false,"summary":null,"term":"MONDO:0060627"}]},"cv_name":"mondo","definition":"A rare, genetic, syndromic intellectual disability characterized by global developmental delay, early-onset seizures, cerebellar atrophy, osteopenia, nystagmus and dysmorphic facial features, including bitemporal narrowing, prominent forehead, anteverted nares. Dysarthria, dysmetria, ataxic gait, spasticity and dysmorphic features have also been associated.","definition_xrefs":["Orphanet:529665"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"central nervous system malformation","termid":"MONDO:0020022"},{"relation_name":"is_a","term_name":"inherited lipid metabolism disorder","termid":"MONDO:0002525"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"congenital disorder of glycosylation","termid":"MONDO:0015286"},{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"disorder of GPI anchor biosynthesis","termid":"MONDO:0024321"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03292":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0006025","MONDO:0002525","MONDO:0024322"],"is_obsolete":false,"name":"glycosylphosphatidylinositol biosynthesis defect 15","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1615160","OMIM:617810","UMLS:C4540520","GARD:17969"],"synonyms":[{"name":"GPIBD15","type":"related"},{"name":"developmental delay, epilepsy, cerebellar atrophy, and osteopenia","type":"related"},{"name":"glycosylphosphatidylinositol biosynthesis defect 15","type":"exact"}],"termid":"MONDO:0060627","terms_by_termid":{"MONDO:0060627":null},"xrefs":{"Monarch":{"xref_id":"0060627"}}}


id: PBO:0032716
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_error-free_translesion_synthesis","termid":"PBO:0032716"}


id: PBO:0004513
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.3.1.16","termid":"PBO:0004513"}


id: PBO:0047740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibronectin type III domain containing 3C, pseudogene","termid":"PBO:0047740"}


id: MONDO:0006962
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An adenocarcinoma with sebaceous differentiation. It presents as a painless mass and it may be multifocal. It grows in the ocular adnexae and in the skin of head and neck, trunk, genitals, and extremities. It is characterized by the presence of malignant cells with multivesicular and clear cytoplasm. It may recur and metastasize.","definition_xrefs":["NCIT:C40310"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenocarcinoma","termid":"MONDO:0004970"},{"relation_name":"is_a","term_name":"skin appendage carcinoma","termid":"MONDO:0006973"},{"relation_name":"is_a","term_name":"sebaceous gland cancer","termid":"MONDO:0037735"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0004992"],"is_obsolete":false,"name":"sebaceous adenocarcinoma","secondary_identifiers":["DOID:4839","SCTID:307599002","DOID:4840","NCIT:C8409","ONCOTREE:SEBA","MESH:D018266","UMLS:C0206684","MEDGEN:64632","EFO:1001171","ICDO:8410/3"],"synonyms":[{"name":"Seba","type":"related"},{"name":"adenocarcinoma of the sebaceous gland","type":"exact"},{"name":"adenocarcinoma, sebaceous, malignant","type":"exact"},{"name":"carcinoma of sebaceous gland","type":"exact"},{"name":"carcinoma of the sebaceous gland","type":"exact"},{"name":"malignant sebaceous tumor","type":"narrow"},{"name":"malignant sebaceous tumour","type":"narrow"},{"name":"sebaceous cancer","type":"exact"},{"name":"sebaceous carcinoma","type":"exact"},{"name":"sebaceous gland adenocarcinoma","type":"exact"},{"name":"sebaceous gland carcinoma","type":"exact"}],"termid":"MONDO:0006962","xrefs":{"Monarch":{"xref_id":"0006962"}}}


id: PBO:0039748
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"apolipoprotein O","termid":"PBO:0039748"}


id: PomGeneEx:0000017
data:
  {"annotation_feature_type":"gene","cv_name":"PomGeneExRNA","definition":"A gene expression qualifier that indicates that an RNA is present at levels that vary under two or more sets of conditions or over a time course.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fluctuates","termid":"PomGeneEx:0000008"},{"relation_name":"is_a","term_name":"RNA expression level","termid":"PomGeneEx:0000009"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA level fluctuates","synonyms":[{"name":"RNA expression fluctuates","type":"exact"},{"name":"fluctuating RNA level","type":"exact"}],"termid":"PomGeneEx:0000017"}


id: PBO:0077580
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMLHE antisense RNA 1","termid":"PBO:0077580"}


id: GO:1990610
data:
  {"annotated_genes":["SJAG_06635"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[63845],"is_not":false,"summary":null,"term":"GO:1990610"}]},"cv_name":"molecular_function","definition":"Binds to and modulates the activity of acetolactate synthase.","definition_xrefs":["PMID:8972574"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme regulator activity","termid":"GO:0030234"}],"gene_count":1,"genes_by_uniquename":{"SJAG_06635":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0030234","GO:0098772"],"is_obsolete":false,"name":"acetolactate synthase regulator activity","references_by_uniquename":{"GO_REF:0000002":null},"termid":"GO:1990610","terms_by_termid":{"GO:1990610":null}}


id: GO:0090209
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.","definition_xrefs":["GOC:dph","GOC:sl","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of lipid metabolic process","termid":"GO:0045833"},{"relation_name":"is_a","term_name":"regulation of triglyceride metabolic process","termid":"GO:0090207"},{"relation_name":"negatively_regulates","term_name":"triglyceride metabolic process","termid":"GO:0006641"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"negatively_regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"negative regulation of triglyceride metabolic process","termid":"GO:0090209"}


id: GO:1902991
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.","definition_xrefs":["PMID:24499793","GOC:rl","GOC:PARL","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein metabolic process","termid":"GO:0051246"},{"relation_name":"regulates","term_name":"amyloid precursor protein catabolic process","termid":"GO:0042987"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of amyloid precursor protein catabolic process","synonyms":[{"name":"regulation of APP catabolic process","type":"exact"},{"name":"regulation of APP catabolism","type":"exact"},{"name":"regulation of amyloid precursor protein breakdown","type":"exact"},{"name":"regulation of amyloid precursor protein catabolism","type":"exact"},{"name":"regulation of amyloid precursor protein degradation","type":"exact"}],"termid":"GO:1902991"}


id: PBO:0070358
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY4 pseudogene 31","termid":"PBO:0070358"}


id: MONDO:0016141
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"sarcoglycanopathy","termid":"MONDO:0016140"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"qualitative or quantitative defects of alpha-sarcoglycan","secondary_identifiers":["MEDGEN:1842296","Orphanet:207060","UMLS:C5680808","GARD:20390"],"synonyms":[{"name":"alpha-sarcoglycanopathy","type":"exact"}],"termid":"MONDO:0016141","xrefs":{"Monarch":{"xref_id":"0016141"}}}


id: PBO:0028337
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_spatial_extent_of_CENP-A_containing_nucleosome_assembly","termid":"PBO:0028337"}


id: GO:0048354
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.","definition_xrefs":["GOC:tb","GOC:dph","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mucilage biosynthetic process","termid":"GO:0010192"},{"relation_name":"is_a","term_name":"mucilage metabolic process involved in seed coat development","termid":"GO:0048359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mucilage biosynthetic process involved in seed coat development","synonyms":[{"name":"mucilage anabolism during seed coat development","type":"exact"},{"name":"mucilage biosynthetic process during seed coat development","type":"related"},{"name":"mucilage formation during seed coat development","type":"exact"},{"name":"mucilage synthesis during seed coat development","type":"exact"}],"termid":"GO:0048354"}


id: PBO:0052467
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLF transcription factor 13","termid":"PBO:0052467"}


id: GO:1904681
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.","definition_xrefs":["GOC:mr","PMID:9224771","GO_REF:0000071","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to polycyclic arene","termid":"GO:1903165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to 3-methylcholanthrene","termid":"GO:1904681"}


id: MONDO:0016135
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare hereditary neurologic disease with peripheral neuropathy (obsolete MONDO:0016135)","secondary_identifiers":["Orphanet:207025"],"termid":"MONDO:0016135","xrefs":{"Monarch":{"xref_id":"0016135"}}}


id: PBO:0084846
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit","termid":"PBO:0084846"}


id: MONDO:0016637
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete thrombotic disorder due to an acquired platelet anomaly (obsolete MONDO:0016637)","secondary_identifiers":["Orphanet:248404"],"termid":"MONDO:0016637","xrefs":{"Monarch":{"xref_id":"0016637"}}}


id: GO:1902781
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.","definition_xrefs":["PMID:22958739","GO_REF:0000071","GOC:TermGenie","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to alkane","termid":"GO:1902779"},{"relation_name":"is_a","term_name":"response to nonane","termid":"GO:1902780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to nonane","termid":"GO:1902781"}


id: PBO:0058428
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4798","termid":"PBO:0058428"}


id: PR:Q9USS4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC557.02c gene.","definition_xrefs":["UniProtKB:Q9USS4","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C557.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC557.02c","synonyms":[{"name":"Spom972h-SPBC557.02c","type":"exact"}],"termid":"PR:Q9USS4"}


id: PR:Q9HDW6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- vma5 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9HDW6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-type proton ATPase subunit C (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB2B4.05","synonyms":[{"name":"Spom972h-vma5","type":"exact"},{"name":"V-ATPase subunit C (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"vacuolar proton pump subunit C (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9HDW6"}


id: MOD:01916
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-tyrosine residue to O4'-(N-acetylamino)galactosyl-L-tyrosine.","definition_xrefs":["RESID:AA0577","PubMed:21983924","PubMed:21712440"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acetylaminogalactosylated residue","termid":"MOD:00563"},{"relation_name":"is_a","term_name":"O-glycosyl-L-tyrosine","termid":"MOD:01927"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"O4'-(N-acetylamino)galactosyl-L-tyrosine","synonyms":[{"name":"(2S)-2-amino-3-(D-2-acetamido-2-deoxygalactopyranosyloxy)phenylpropanoic acid","type":"exact"},{"name":"CARBOHYD O-linked (GalNAc) tyrosine","type":"exact"},{"name":"O4'-(N-acetylamino)galactosyl-L-tyrosine","type":"exact"},{"name":"O4'-(N-acetylgalactosaminyl)tyrosine","type":"exact"},{"name":"O4'-glycosyl-L-tyrosine","type":"exact"},{"name":"mucin type O-glycosyltyrosine","type":"exact"}],"termid":"MOD:01916"}


id: PBO:0087934
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Translational elongation factor EF-1 alpha; GTP-bound active form, binds to and delivers aminoacylated tRNA to the A-site of ribosomes for elongation of nascent polypeptides; moonlighting function as an actin binding and bundling protein; association with GTPase Rho1p on the vacuolar membrane may facilitate F-actin remodeling; involved in tRNA re-export from the nucleus","termid":"PBO:0087934"}


id: PBO:0055446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2877","termid":"PBO:0055446"}


id: PBO:0005312
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human COQ10A","termid":"PBO:0005312"}


id: PBO:0034113
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-results_in_disassembly_of","termid":"PBO:0034113"}


id: GO:0014726
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.","definition_xrefs":["GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of extraocular skeletal muscle development","termid":"GO:0014725"},{"relation_name":"is_a","term_name":"negative regulation of skeletal muscle tissue development","termid":"GO:0048642"},{"relation_name":"negatively_regulates","term_name":"extraocular skeletal muscle development","termid":"GO:0002074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of extraocular skeletal muscle development","termid":"GO:0014726"}


id: PR:O94688
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- apc15 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94688"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaphase-promoting complex subunit 15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC83.04","synonyms":[{"name":"20S cyclosome/APC complex protein apc15 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-apc15","type":"exact"}],"termid":"PR:O94688"}


id: GO:0097313
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.","definition_xrefs":["GOC:imk","PMID:22571672","Wikipedia:Biofilm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"bacterial biofilm matrix","termid":"GO:0097311"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"bacterial biofilm matrix surface","termid":"GO:0097313"}


id: GO:0047935
data:
  {"annotated_genes":["SJAG_02148"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[118189],"is_not":false,"summary":null,"term":"GO:0047935"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.","definition_xrefs":["EC:1.1.1.119","MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucose 1-dehydrogenase [NAD(P)+] activity","termid":"GO:0047936"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02148":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"glucose 1-dehydrogenase (NADP+) activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["RHEA:14405"],"synonyms":[{"name":"D-glucose:NADP+ 1-oxidoreductase activity","type":"related"},{"name":"NADP-dependent glucose dehydrogenase activity","type":"related"},{"name":"NADP-linked aldohexose dehydrogenase activity","type":"related"},{"name":"nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity","type":"related"}],"termid":"GO:0047935","terms_by_termid":{"GO:0047935":null}}


id: PR:O13658
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pho7 gene.","definition_xrefs":["UniProtKB:O13658","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized transcriptional regulatory protein C27B12.11c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC27B12.11c","synonyms":[{"name":"Spom972h-pho7","type":"exact"}],"termid":"PR:O13658"}


id: GO:0016651
data:
  {"annotated_genes":["SJAG_00235","SJAG_03098","SJAG_05015","SJAG_02154","SJAG_01869","SJAG_00972","SJAG_04270","SJAG_02191","SJAG_01539","SJAG_02794","SJAG_04152","SJAG_03476","SJAG_04397","SJAG_05033","SJAG_02697","SJAG_02395","SJAG_02016"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76818,94869,94870],"is_not":false,"summary":null,"term":"GO:0016651"},{"annotations":[59453,77595,77824],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004128"},{"annotations":[78225],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003955"},{"annotations":[112602],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008137"},{"annotations":[112603,96477],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0050136"},{"annotations":[64700],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003959"},{"annotations":[64650,76976],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003958"},{"annotations":[74118],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003960"},{"annotations":[67793],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016652"},{"annotations":[79708],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016653"},{"annotations":[78891,78975],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0050664"}]},"cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity","termid":"GO:0016491"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00235":null,"SJAG_00972":null,"SJAG_01539":null,"SJAG_01869":null,"SJAG_02016":null,"SJAG_02154":null,"SJAG_02191":null,"SJAG_02395":null,"SJAG_02697":null,"SJAG_02794":null,"SJAG_03098":null,"SJAG_03476":null,"SJAG_04152":null,"SJAG_04270":null,"SJAG_04397":null,"SJAG_05015":null,"SJAG_05033":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"oxidoreductase activity, acting on NAD(P)H","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000003":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-109343","Reactome:R-HSA-8956458","EC:1.6.-.-"],"synonyms":[{"name":"NAD(P)H dehydrogenase","type":"narrow"},{"name":"oxidoreductase activity, acting on NADH or NADPH","type":"related"},{"name":"oxidoreductase activity, acting on NADH or NADPH, other acceptor","type":"narrow"}],"termid":"GO:0016651","terms_by_termid":{"GO:0003955":null,"GO:0003958":null,"GO:0003959":null,"GO:0003960":null,"GO:0004128":null,"GO:0008137":null,"GO:0016651":null,"GO:0016652":null,"GO:0016653":null,"GO:0050136":null,"GO:0050664":null}}


id: MONDO:0001795
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A wart in the plantar surface of the foot. It is caused by human papillomavirus.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin disorder caused by infection","termid":"MONDO:0024294"},{"relation_name":"is_a","term_name":"benign epithelial skin neoplasm","termid":"MONDO:0024666"},{"relation_name":"is_a","term_name":"primary viral infectious disease","termid":"MONDO:0100329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"plantar wart","secondary_identifiers":["DOID:13775","MEDGEN:53003","ICD9:078.12","UMLS:C0042548","EFO:1002023","NCIT:C26913","ICD10CM:B07.0","SCTID:63440008"],"synonyms":[{"name":"plantar wart","type":"exact"},{"name":"verruca plantaris","type":"exact"}],"termid":"MONDO:0001795","xrefs":{"Monarch":{"xref_id":"0001795"}}}


id: PBO:0073946
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 20 member 1","termid":"PBO:0073946"}


id: GO:1904658
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste.","definition_xrefs":["PMID:1716172","GO_REF:0000058","GOC:mr","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of nervous system process","termid":"GO:0031646"},{"relation_name":"is_a","term_name":"regulation of sensory perception of sweet taste","termid":"GO:1904656"},{"relation_name":"positively_regulates","term_name":"sensory perception of sweet taste","termid":"GO:0050916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of sensory perception of sweet taste","synonyms":[{"name":"activation of sensory perception of sweet taste","type":"narrow"},{"name":"activation of sweet taste perception","type":"narrow"},{"name":"positive regulation of sweet taste perception","type":"exact"},{"name":"up regulation of sensory perception of sweet taste","type":"exact"},{"name":"up regulation of sweet taste perception","type":"exact"},{"name":"up-regulation of sensory perception of sweet taste","type":"exact"},{"name":"up-regulation of sweet taste perception","type":"exact"},{"name":"upregulation of sensory perception of sweet taste","type":"exact"},{"name":"upregulation of sweet taste perception","type":"exact"}],"termid":"GO:1904658"}


id: PBO:0000919
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaphase-promoting complex subunit Apc8","termid":"PBO:0000919"}


id: MONDO:0015616
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare genetic intestinal disease (obsolete MONDO:0015616)","secondary_identifiers":["Orphanet:165655"],"synonyms":[{"name":"genetic intestinal disease","type":"exact"}],"termid":"MONDO:0015616","xrefs":{"Monarch":{"xref_id":"0015616"}}}


id: PBO:0051249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable (III)-5-1 (pseudogene)","termid":"PBO:0051249"}


id: GO:0060952
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glial cell development","termid":"GO:0021782"},{"relation_name":"is_a","term_name":"cardiac cell development","termid":"GO:0055006"},{"relation_name":"part_of","term_name":"cardiac glial cell differentiation","termid":"GO:0060950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac glial cell development","termid":"GO:0060952"}


id: GO:1904392
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.","definition_xrefs":["GOC:TermGenie","PMID:16914133","GO_REF:0000071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to nitrogen compound","termid":"GO:1901699"},{"relation_name":"is_a","term_name":"response to ciliary neurotrophic factor","termid":"GO:1904391"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to ciliary neurotrophic factor","termid":"GO:1904392"}


id: GO:0034670
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a motile cell or organism in response to the presence of arachidonic acid.","definition_xrefs":["PMID:18202452","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemotaxis","termid":"GO:0006935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chemotaxis to arachidonate","synonyms":[{"name":"chemotaxis to arachidonic acid","type":"exact"}],"termid":"GO:0034670"}


id: PBO:0069919
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1211, pseudogene","termid":"PBO:0069919"}


id: GO:0045844
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of striated muscle development.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of striated muscle tissue development","termid":"GO:0016202"},{"relation_name":"is_a","term_name":"positive regulation of muscle organ development","termid":"GO:0048636"},{"relation_name":"is_a","term_name":"positive regulation of muscle tissue development","termid":"GO:1901863"},{"relation_name":"positively_regulates","term_name":"striated muscle tissue development","termid":"GO:0014706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of striated muscle tissue development","synonyms":[{"name":"activation of striated muscle development","type":"narrow"},{"name":"stimulation of striated muscle development","type":"narrow"},{"name":"up regulation of striated muscle development","type":"exact"},{"name":"up-regulation of striated muscle development","type":"exact"},{"name":"upregulation of striated muscle development","type":"exact"}],"termid":"GO:0045844"}


id: GO:0061211
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"collecting duct development","termid":"GO:0072044"},{"relation_name":"part_of","term_name":"mesonephros development","termid":"GO:0001823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric collecting duct development","termid":"GO:0061211"}


id: MONDO:0004662
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An infection that is caused by the intestinal fluke Heterophyes heterophyes, which is most commonly found in Asia, the Middle East, and Africa, and which is transmitted via consumption of contaminated raw or undercooked fish. Symptoms typically range from asymptomatic to intermittent abdominal pain and diarrhea, with occasional ectopic infection.","definition_xrefs":["NCIT:C128389"],"direct_ancestors":[{"relation_name":"is_a","term_name":"helminthiasis","termid":"MONDO:0004664"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterophyiasis","secondary_identifiers":["ICD9:121.6","SCTID:22905009","icd11.foundation:322536023","UMLS:C0152071","DOID:882","MEDGEN:508869"],"synonyms":[{"name":"Heterophyes infection","type":"exact"},{"name":"Heterophyes infectious disease","type":"exact"},{"name":"infections, Heterophyes","type":"related"}],"termid":"MONDO:0004662","xrefs":{"Monarch":{"xref_id":"0004662"}}}


id: PBO:0004137
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"does not functionally complement S. cerevisiae PRP6","termid":"PBO:0004137"}


id: GO:0042331
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a motile cell or organism in response to light.","definition_xrefs":["ISBN:0192800981","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to light stimulus","termid":"GO:0009416"},{"relation_name":"is_a","term_name":"energy taxis","termid":"GO:0009453"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"phototaxis","secondary_identifiers":["Wikipedia:Phototaxis","GO:0046953"],"synonyms":[{"name":"phototactic behavior","type":"exact"},{"name":"phototactic behaviour","type":"exact"},{"name":"taxis in response to light","type":"exact"}],"termid":"GO:0042331"}


id: MONDO:0018514
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Any of the forms of epithelial neoplasm of rectum that have a rare incidence.","definition_xrefs":["MONDO:patterns/rare"],"gene_count":0,"genotype_count":0,"name":"obsolete rare epithelial tumor of rectum (obsolete MONDO:0018514)","secondary_identifiers":["Orphanet:423998"],"synonyms":[{"name":"rare epithelial neoplasm of rectum","type":"exact"},{"name":"rare rectal epithelial tumor","type":"exact"}],"termid":"MONDO:0018514","xrefs":{"Monarch":{"xref_id":"0018514"}}}


id: PBO:0036007
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_heterochromatin_at_centromere_outer_repeat","termid":"PBO:0036007"}


id: GO:0050122
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-acetyl-D-glucosamine + H2O + O2 = N-acetyl-D-glucosaminate + H2O2 + H+.","definition_xrefs":["RHEA:13029","EC:1.1.3.29"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor","termid":"GO:0016899"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"N-acylhexosamine oxidase activity","secondary_identifiers":["MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN","KEGG_REACTION:R01203"],"synonyms":[{"name":"N-acyl-D-hexosamine oxidase activity","type":"related"},{"name":"N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity","type":"related"},{"name":"N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity","type":"related"}],"termid":"GO:0050122"}


id: FYPO:0002308
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of IMP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal molecular function","termid":"FYPO:0000707"},{"relation_name":"is_a","term_name":"binding phenotype","termid":"FYPO:0001092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0001985","FYPO:0000707"],"is_obsolete":false,"name":"abnormal IMP binding","termid":"FYPO:0002308"}


id: GO:0060240
data:
  {"annotated_genes":["SJAG_00990"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[93092],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090029"}]},"cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of the series signal transduction involved in conjugation with cellular fusion.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"regulation of signal transduction involved in conjugation with cellular fusion","termid":"GO:0060238"},{"relation_name":"is_a","term_name":"negative regulation of reproductive process","termid":"GO:2000242"},{"relation_name":"negatively_regulates","term_name":"signal transduction involved in positive regulation of conjugation with cellular fusion","termid":"GO:0032005"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00990":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0000747"}],"interesting_parent_ids":["GO:0000747","GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of signal transduction involved in conjugation with cellular fusion","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0060240","terms_by_termid":{"GO:0090029":null}}


id: GO:0031581
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.","definition_xrefs":["PMID:15983403","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-substrate junction assembly","termid":"GO:0007044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"hemidesmosome assembly","secondary_identifiers":["Reactome:R-HSA-446107"],"termid":"GO:0031581"}


id: PBO:0056658
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit 25","termid":"PBO:0056658"}


id: GO:0030961
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-arginine modification","termid":"GO:0018195"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-arginine hydroxylation","termid":"GO:0030961"}


id: SO:0001823
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An inframe increase in cds length that inserts one or more codons into the coding sequence between existing codons.","definition_xrefs":["EBI:gr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inframe_insertion","termid":"SO:0001821"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conservative_inframe_insertion","synonyms":[{"name":"conservative increase in CDS length","type":"exact"},{"name":"conservative inframe insertion","type":"exact"}],"termid":"SO:0001823"}


id: GO:0048767
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the root hair grows longer.","definition_xrefs":["GOC:jid","PMID:12468740"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental cell growth","termid":"GO:0048588"},{"relation_name":"is_a","term_name":"developmental growth involved in morphogenesis","termid":"GO:0060560"},{"relation_name":"part_of","term_name":"root hair cell development","termid":"GO:0080147"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"root hair elongation","termid":"GO:0048767"}


id: PBO:0083655
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity","termid":"PBO:0083655"}


id: MONDO:0012285
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"left ventricular noncompaction","termid":"MONDO:0018901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"left ventricular noncompaction 2","secondary_identifiers":["OMIM:609470","GARD:15460","MEDGEN:322827","UMLS:C1836118"],"synonyms":[{"name":"LVNC2","type":"exact"},{"name":"left ventricular noncompaction 2","type":"exact"}],"termid":"MONDO:0012285","xrefs":{"Monarch":{"xref_id":"0012285"}}}


id: PBO:0005816
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exosome subunit Csl4 (predicted)","termid":"PBO:0005816"}


id: MONDO:0000806
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A allergy involving a Turbo cornutus.","definition_xrefs":["MONDO:patterns/allergy"],"gene_count":0,"genotype_count":0,"name":"obsolete horned turban snail allergy (obsolete MONDO:0000806)","secondary_identifiers":["DOID:0060531"],"synonyms":[{"name":"Turbo cornutus allergic disease","type":"exact"},{"name":"Turbo cornutus allergy","type":"exact"},{"name":"Turbo cornutus caused allergic disease","type":"exact"},{"name":"allergy of Turbo cornutus","type":"exact"}],"termid":"MONDO:0000806","xrefs":{"Monarch":{"xref_id":"0000806"}}}


id: PBO:0073765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 4 member 1 (Diego blood group)","termid":"PBO:0073765"}


id: GO:0000705
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.","definition_xrefs":["PMID:10690419","GOC:elh","GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiosis I","termid":"GO:0007127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0140013"}],"interesting_parent_ids":["GO:0140013","GO:0007049","GO:0008150"],"is_obsolete":false,"name":"achiasmate meiosis I","synonyms":[{"name":"achiasmate meiosis I nuclear division","type":"exact"}],"termid":"GO:0000705"}


id: PBO:0088456
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytoplasmic cysteine-tRNA ligase Crs1","termid":"PBO:0088456"}


id: MOD:00084
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.","definition_xrefs":["PubMed:14570711","PubMed:12964758","PubMed:3100523","PubMed:10550045","PubMed:8453381","Unimod:36#K","RESID:AA0075","OMSSA:36"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dimethylated residue","termid":"MOD:00429"},{"relation_name":"is_a","term_name":"N-methylated residue","termid":"MOD:00602"},{"relation_name":"is_a","term_name":"methylated lysine","termid":"MOD:00663"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"N6,N6-dimethyl-L-lysine","synonyms":[{"name":"(2S)-2-amino-6-(dimethylamino)hexanoic acid","type":"exact"},{"name":"Dimethyl","type":"related"},{"name":"MOD_RES N6,N6-dimethyllysine","type":"exact"},{"name":"N(zeta)-dimethyllysine","type":"exact"},{"name":"N6,N6-dimethyl-L-lysine","type":"exact"},{"name":"N6,N6-dimethylated L-lysine","type":"exact"},{"name":"N6Me2Lys","type":"exact"},{"name":"di-Methylation","type":"related"},{"name":"dimethylk","type":"exact"},{"name":"epsilon-dimethyllysine","type":"exact"},{"name":"lysine derivative Lys(y)","type":"exact"}],"termid":"MOD:00084"}


id: GO:0031332
data:
  {"annotated_genes":["SJAG_04061","SJAG_03916","SJAG_02594","SJAG_03706","SJAG_03042","SJAG_02621"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[64611],"is_not":false,"summary":null,"term":"GO:0031332"},{"annotations":[88535,117824,62815],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033167"},{"annotations":[117830,91032,111953],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030958"}]},"cv_name":"cellular_component","definition":"Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins.","definition_xrefs":["GOC:mah","PMID:14704433"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribonucleoprotein complex","termid":"GO:1990904"}],"gene_count":6,"genes_by_uniquename":{"SJAG_02594":null,"SJAG_02621":null,"SJAG_03042":null,"SJAG_03706":null,"SJAG_03916":null,"SJAG_04061":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"RNAi effector complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000107":null},"termid":"GO:0031332","terms_by_termid":{"GO:0030958":null,"GO:0031332":null,"GO:0033167":null}}


id: PBO:0087732
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the signal peptidase complex (SPC); SPC cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER); homolog of the SPC12 subunit of mammalian signal peptidase complex; protein abundance increases in response to DNA replication stress","termid":"PBO:0087732"}


id: PBO:0079739
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBX domain protein 6","termid":"PBO:0079739"}


id: GO:0043059
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of locomotion","termid":"GO:0040012"},{"relation_name":"regulates","term_name":"forward locomotion","termid":"GO:0043056"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of forward locomotion","termid":"GO:0043059"}


id: GO:0002570
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"somatic diversification of immune receptors by N region addition","termid":"GO:0002569"},{"relation_name":"is_a","term_name":"somatic diversification of immunoglobulins","termid":"GO:0016445"},{"relation_name":"part_of","term_name":"somatic recombination of immunoglobulin gene segments","termid":"GO:0016447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006310"}],"interesting_parent_ids":["GO:0006259","GO:0010467","GO:0006310","GO:0008150"],"is_obsolete":false,"name":"somatic diversification of immunoglobulin genes by N region addition","synonyms":[{"name":"somatic diversification of antibody genes by N region addition","type":"exact"}],"termid":"GO:0002570"}


id: MONDO:0011972
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A complication of ovulation induction in infertility treatment. It is graded by the severity of symptoms which include ovary enlargement, multiple ovarian follicles; ovarian cysts; ascites; and generalized edema. The full-blown syndrome may lead to renal failure, respiratory distress, and even death. Increased capillary permeability is caused by the vasoactive substances, such as vascular endothelial growth factors, secreted by the overly-stimulated ovaries.","definition_xrefs":["MESH:D016471"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"ovarian disorder","termid":"MONDO:0005558"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovarian hyperstimulation syndrome","secondary_identifiers":["icd11.foundation:1216664013","ICD9:256.1","Orphanet:64739","MedDRA:10033266","SCTID:129635004","GARD:16668","OMIM:608115","UMLS:C0085083","DOID:5425","MEDGEN:38966"],"synonyms":[{"name":"OHSS","type":"exact"},{"name":"ovarian hyperstimulation syndrome","type":"exact"},{"name":"ovarian hyperstimulation syndrome, familial gestational spontaneous","type":"related"},{"name":"secondary Meig's syndrome","type":"exact"}],"termid":"MONDO:0011972","xrefs":{"Monarch":{"xref_id":"0011972"}}}


id: GO:0047079
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O2 = 2-deoxy-D-ribono-1,4-lactone + CO2 + succinate + uracil.","definition_xrefs":["EC:1.14.11.10","RHEA:23316"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"deoxyuridine 1'-dioxygenase activity","secondary_identifiers":["KEGG_REACTION:R02486","MetaCyc:1.14.11.10-RXN"],"synonyms":[{"name":"2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)","type":"related"},{"name":"pyrimidine-deoxynucleoside 1'-dioxygenase activity","type":"broad"},{"name":"pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity","type":"broad"}],"termid":"GO:0047079"}


id: GO:0047745
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: chlorogenate + H2O = (-)-quinate + cis-caffeate + H+.","definition_xrefs":["EC:3.1.1.42","RHEA:20689"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016788","GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"chlorogenate hydrolase activity","secondary_identifiers":["KEGG_REACTION:R02997","MetaCyc:CHLOROGENATE-HYDROLASE-RXN"],"synonyms":[{"name":"chlorogenase activity","type":"related"},{"name":"chlorogenic acid esterase activity","type":"related"}],"termid":"GO:0047745"}


id: PBO:0050271
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosomal binding domain 3","termid":"PBO:0050271"}


id: PBO:0001663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Brix domain protein Rpf1 (predicted)","termid":"PBO:0001663"}


id: MONDO:0013867
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Brown-Vialetto-van Laere syndrome in which the cause of the disease is a mutation in the SLC52A2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"riboflavin transporter deficiency","termid":"MONDO:0008891"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"Brown-Vialetto-van Laere syndrome 2","secondary_identifiers":["NCIT:C183529","UMLS:C3553538","HGNC:30224","MEDGEN:766452","OMIM:614707","DOID:0080786","GARD:12861","Orphanet:572550"],"synonyms":[{"name":"BVVLS2","type":"exact"},{"name":"Brown-Vialetto-Van Laere syndrome type 2","type":"exact"},{"name":"Brown-Vialetto-van Laere syndrome 2","type":"exact"},{"name":"Brown-Vialetto-van Laere syndrome caused by mutation in SLC52A2","type":"exact"},{"name":"SLC52A2 Brown-Vialetto-van Laere syndrome","type":"exact"}],"termid":"MONDO:0013867","xrefs":{"Monarch":{"xref_id":"0013867"}}}


id: PBO:0026711
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_complex_binding","termid":"PBO:0026711"}


id: PBO:0081728
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 658","termid":"PBO:0081728"}


id: FYPO:0001934
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing glycerol as the carbon source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased cell population growth on glycerol carbon source","termid":"FYPO:0000684"},{"relation_name":"is_a","term_name":"abolished vegetative cell population growth","termid":"FYPO:0001575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0000139","FYPO:0002058","FYPO:0001985","FYPO:0002060","FYPO:0005447","FYPO:0000003"],"is_obsolete":false,"name":"abolished cell population growth on glycerol carbon source","synonyms":[{"name":"abolished glycerol utilization","type":"related"},{"name":"abolished growth on glycerol carbon source","type":"broad"},{"name":"abolished vegetative cell population growth on glycerol carbon source","type":"exact"},{"name":"cell population growth on glycerol carbon source abolished","type":"exact"}],"termid":"FYPO:0001934"}


id: MONDO:0100072
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Neonatal diabetes, congenital sensorineural hearing loss and congenital cataracts is characterized by the three primary phenotypes of neonatal diabetes, congenital sensorineural hearing loss and congenital cataracts. Cases have reported additional varying phenotypes, including optic atrophy, hypothyroidism, severe neonatal hypotonia in males, developmental delay, facial abnormalities, and a few other more rare phenotypes. The severity and congenital onset of the phenotypes distinguish these patients from Wolfram-like syndrome patients.","definition_xrefs":["PMID:27217304","PMID:28468959"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neonatal diabetes, congenital sensorineural hearing loss and congenital cataracts","termid":"MONDO:0100072","xrefs":{"Monarch":{"xref_id":"0100072"}}}


id: GO:0021953
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.","definition_xrefs":["GOC:jid","GOC:dph","GO_REF:0000021","GOC:dgh","GOC:cls"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron differentiation","termid":"GO:0030182"},{"relation_name":"part_of","term_name":"central nervous system development","termid":"GO:0007417"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"central nervous system neuron differentiation","termid":"GO:0021953"}


id: GO:1990882
data:
  {"annotated_genes":["SJAG_01877"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71992],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904812"}]},"cv_name":"biological_process","definition":"The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.","definition_xrefs":["PMID:25402480"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA modification","termid":"GO:0000154"},{"relation_name":"is_a","term_name":"RNA acetylation","termid":"GO:1990884"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01877":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0042254"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0042254","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"rRNA acetylation","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:1990882","terms_by_termid":{"GO:1904812":null}}


id: PBO:0071311
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L26 pseudogene 34","termid":"PBO:0071311"}


id: PBO:0039877
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GTPase activating protein 33","termid":"PBO:0039877"}


id: GO:0010851
data:
  {"annotated_genes":["SJAG_02444"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[93991],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010856"}]},"cv_name":"molecular_function","definition":"Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme regulator activity","termid":"GO:0030234"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02444":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0030234","GO:0098772","GO:0003674"],"is_obsolete":false,"name":"cyclase regulator activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0010851","terms_by_termid":{"GO:0010856":null}}


id: MONDO:1010755
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary sparse hair and dental aplasia in cattle associated with a variation in the EDA gene.","definition_xrefs":["PMID:38252617"],"direct_ancestors":[{"relation_name":"is_a","term_name":"X-linked disease, non-human animal","termid":"MONDO:1012575"},{"relation_name":"is_a","term_name":"hypohidrotic ectodermal dysplasia, non-human animal","termid":"MONDO:1012576"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-linked hypohidrotic ectodermal dysplasia, EDA-related, cattle","secondary_identifiers":["OMIA:000543-9913"],"termid":"MONDO:1010755","xrefs":{"Monarch":{"xref_id":"1010755"}}}


id: PBO:0018219
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Siderophore TRansporter","termid":"PBO:0018219"}


id: MONDO:0011590
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anisomastia","secondary_identifiers":["UMLS:C1854013","OMIM:605746","MESH:C565299","MEDGEN:381317"],"synonyms":[{"name":"anisomastia","type":"exact"}],"termid":"MONDO:0011590","xrefs":{"Monarch":{"xref_id":"0011590"}}}


id: PR:Q9P6K1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A vesicle transport protein SFT2C that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein transport protein sft2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1527.02","secondary_identifiers":["UniProtKB:Q9P6K1"],"synonyms":[{"name":"SPAC1527.02","type":"related"},{"name":"Spom972h-SFT2D3","type":"exact"}],"termid":"PR:Q9P6K1"}


id: MONDO:0020730
data:
  {"annotated_genes":["SJAG_04300"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85767],"is_not":false,"summary":null,"term":"MONDO:0020730"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"carpal tunnel syndrome","termid":"MONDO:0007275"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04300":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"carpal tunnel syndrome 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:115430","MEDGEN:1830382","UMLS:C5779776","DOID:0070466"],"synonyms":[{"name":"CTS","type":"related"},{"name":"CTS1","type":"exact"},{"name":"amyotrophy, thenar, of carpal origin","type":"exact"},{"name":"carpal tunnel syndrome","type":"broad"},{"name":"carpal tunnel syndrome, familial","type":"exact"}],"termid":"MONDO:0020730","terms_by_termid":{"MONDO:0020730":null},"xrefs":{"Monarch":{"xref_id":"0020730"}}}


id: FYECO:0000135
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"The assay, or growth of cells, was conducted under semi-anaerobic conditions, where the level of oxygen is lower than normal.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping experimental environment","termid":"FYECO:0000132"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"semi-aerobic environment","synonyms":[{"name":"hypoxia","type":"related"},{"name":"hypoxic environment","type":"related"},{"name":"limited O atoms","type":"related"},{"name":"limited oxygen","type":"related"},{"name":"reduced oxygen level","type":"related"},{"name":"semi aerobic environment","type":"exact"},{"name":"semi-anaerobic environment","type":"exact"},{"name":"semiaerobic environment","type":"exact"},{"name":"semianaerobic environment","type":"exact"}],"termid":"FYECO:0000135"}


id: PBO:0030242
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_RNA_level_during_cellular_response_to_endoplasmic_reticulum_stress","termid":"PBO:0030242"}


id: PBO:0114427
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LDLRAD4 antisense RNA 2","termid":"PBO:0114427"}


id: GO:0031408
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.","definition_xrefs":["PMID:11960741","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxylipin metabolic process","termid":"GO:0031407"},{"relation_name":"is_a","term_name":"carboxylic acid biosynthetic process","termid":"GO:0046394"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"oxylipin biosynthetic process","synonyms":[{"name":"oxylipin anabolism","type":"exact"},{"name":"oxylipin biosynthesis","type":"exact"},{"name":"oxylipin formation","type":"exact"},{"name":"oxylipin synthesis","type":"exact"}],"termid":"GO:0031408"}


id: PBO:0050298
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 like 3","termid":"PBO:0050298"}


id: PBO:0051322
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin kappa variable 1/OR22-5 (pseudogene)","termid":"PBO:0051322"}


id: PBO:0011509
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eisosome BAR domain protein Pil1","termid":"PBO:0011509"}


id: FYECO:0000039
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which P-factor was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ mating pheromone","termid":"FYECO:0000058"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ P-factor","synonyms":[{"name":"P factor added","type":"exact"}],"termid":"FYECO:0000039"}


id: PBO:0071750
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L41 pseudogene 6","termid":"PBO:0071750"}


id: SO:0001433
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A three prime RACE (Rapid Amplification of cDNA Ends) clone is a cDNA clone copied from the 3' end of an mRNA (using a poly-dT primer to capture the polyA tail and a gene-specific or randomly primed 5' primer), and spliced into a vector for propagation in a suitable host.","definition_xrefs":["modENCODE:nlw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cDNA_clone","termid":"SO:0000317"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"three_prime_RACE_clone","synonyms":[{"name":"3' RACE clone","type":"related"}],"termid":"SO:0001433"}


id: MONDO:0013379
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Noonan syndrome in which the cause of the disease is a mutation in the BRAF gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Noonan syndrome","termid":"MONDO:0018997"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005267"],"is_obsolete":false,"name":"Noonan syndrome 7","secondary_identifiers":["DOID:0060585","GARD:15693","NCIT:C176935","UMLS:C3150970","OMIM:613706","MEDGEN:462320"],"synonyms":[{"name":"BRAF Noonan syndrome","type":"exact"},{"name":"NS7","type":"exact"},{"name":"Noonan syndrome 7","type":"exact"},{"name":"Noonan syndrome caused by mutation in BRAF","type":"exact"},{"name":"Noonan syndrome type 7","type":"exact"}],"termid":"MONDO:0013379","xrefs":{"Monarch":{"xref_id":"0013379"}}}


id: MONDO:0030979
data:
  {"annotated_genes":["SJAG_03758"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85328],"is_not":false,"summary":null,"term":"MONDO:0030979"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"EN1-related dorsoventral syndrome","termid":"MONDO:1040032"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03758":null},"genotype_count":0,"is_obsolete":false,"name":"ENDOVE syndrome, limb-brain type","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5543142","OMIM:619218","MEDGEN:1782954","GARD:18561"],"synonyms":[{"name":"ENDOVESLB","type":"exact"},{"name":"Mesomelia of Lower Extremities With Hand, Foot, and Brain Anomalies","type":"exact"}],"termid":"MONDO:0030979","terms_by_termid":{"MONDO:0030979":null},"xrefs":{"Monarch":{"xref_id":"0030979"}}}


id: GO:0018309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete protein-FMN linkage (obsolete GO:0018309)","termid":"GO:0018309"}


id: PBO:0051017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"insulin like growth factor 2 mRNA binding protein 3","termid":"PBO:0051017"}


id: PBO:0041560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 19 open reading frame 67","termid":"PBO:0041560"}


id: MONDO:0016784
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete gestational trophoblastic disease (obsolete MONDO:0016784)","secondary_identifiers":["SCTID:416402001","MESH:D031901","ICD9:631","ONCOTREE:GTD","Orphanet:254685"],"termid":"MONDO:0016784","xrefs":{"Monarch":{"xref_id":"0016784"}}}


id: GO:0099170
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modulation of chemical synaptic transmission","termid":"GO:0050804"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"postsynaptic modulation of chemical synaptic transmission","termid":"GO:0099170"}


id: PBO:0077793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"topoisomerase I binding, arginine and serine rich like, pseudogene","termid":"PBO:0077793"}


id: PBO:0003425
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"VRR-NUC nuclease associated domain, human MTMR15 homolog","termid":"PBO:0003425"}


id: PBO:0048151
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FYVE and coiled-coil domain autophagy adaptor 1","termid":"PBO:0048151"}


id: GO:0016306
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. A phosphoinositide 3-kinase which can only phosphorylate phosphatidylinositol.","definition_xrefs":["PMID:9759495"],"gene_count":0,"genotype_count":0,"name":"obsolete phosphatidylinositol 3-kinase activity, class III (obsolete GO:0016306)","synonyms":[{"name":"phosphatidylinositol 3-kinase activity, class III","type":"exact"}],"termid":"GO:0016306"}


id: MONDO:0013069
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An optic atrophy that is caused by a mutation in the TMEM126A gene.","definition_xrefs":["OMIM:612989"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"},{"relation_name":"is_a","term_name":"hereditary optic atrophy","termid":"MONDO:0043878"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"autosomal recessive optic atrophy, OPA7 type","secondary_identifiers":["Orphanet:227976","DOID:0111437","GARD:17143","MEDGEN:414112","MESH:C567833","UMLS:C2751812"],"synonyms":[{"name":"OPA7","type":"related"},{"name":"TMEM126A-related optic atrophy with or without extraocular features","type":"exact"},{"name":"optic atrophy 7","type":"exact"},{"name":"optic atrophy 7 with or without auditory neuropathy","type":"related"}],"termid":"MONDO:0013069","xrefs":{"Monarch":{"xref_id":"0013069"}}}


id: PBO:0056812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"major facilitator superfamily domain containing 5","termid":"PBO:0056812"}


id: MOD:00821
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively crosslinks an L-alanine residue and an L-cysteine residue by a thioester bond to form S-(L-alanyl)-L-cysteine.","definition_xrefs":["RESID:AA0411","PubMed:11807079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thioester crosslinked residues","termid":"MOD:00395"},{"relation_name":"is_a","term_name":"crosslinked residues with loss of water","termid":"MOD:00954"},{"relation_name":"is_a","term_name":"crosslinked L-alanine residue","termid":"MOD:02040"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"S-(L-alanyl)-L-cysteine","synonyms":[{"name":"(2R)-2-amino-3-([(2S)-2-aminopropanoyl]sulfanyl)propanoic acid","type":"exact"},{"name":"CROSSLNK Alanyl cysteine thioester (Cys-Ala)","type":"exact"},{"name":"S-(2-aminopropanoyl)cysteine","type":"exact"},{"name":"S-(L-alanyl)-L-cysteine","type":"exact"},{"name":"XLNK1AlaSCys","type":"exact"},{"name":"alanine cysteine thioester","type":"exact"}],"termid":"MOD:00821"}


id: PBO:0002801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein, G-pathc domain, PINX1 family (predicted)","termid":"PBO:0002801"}


id: GO:0045346
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of macromolecule biosynthetic process","termid":"GO:0010556"},{"relation_name":"regulates","term_name":"MHC class II biosynthetic process","termid":"GO:0045342"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of MHC class II biosynthetic process","synonyms":[{"name":"regulation of MHC class II anabolism","type":"exact"},{"name":"regulation of MHC class II biosynthesis","type":"exact"},{"name":"regulation of MHC class II formation","type":"exact"},{"name":"regulation of MHC class II synthesis","type":"exact"},{"name":"regulation of major histocompatibility complex class II biosynthesis","type":"exact"},{"name":"regulation of major histocompatibility complex class II biosynthetic process","type":"exact"}],"termid":"GO:0045346"}


id: GO:0051248
data:
  {"annotated_genes":["SJAG_00475","SJAG_00423","SJAG_00052","SJAG_00690","SJAG_01528","SJAG_02592","SJAG_05000","SJAG_03048","SJAG_03869","SJAG_00169","SJAG_01942","SJAG_03501","SJAG_02638","SJAG_02026","SJAG_00786","SJAG_04291","SJAG_02244"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[102112],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905785"},{"annotations":[117970,95346,99202,114596],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000766"},{"annotations":[111901,91072],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904689"},{"annotations":[94127,99096,109422,115358,69717,74995],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990625"},{"annotations":[77351,77843],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904293"},{"annotations":[77033,106708],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032435"},{"annotations":[75047],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001125"},{"annotations":[99210],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0141014"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of macromolecule metabolic process","termid":"GO:0010605"},{"relation_name":"is_a","term_name":"regulation of protein metabolic process","termid":"GO:0051246"},{"relation_name":"negatively_regulates","term_name":"protein metabolic process","termid":"GO:0019538"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00052":null,"SJAG_00169":null,"SJAG_00423":null,"SJAG_00475":null,"SJAG_00690":null,"SJAG_00786":null,"SJAG_01528":null,"SJAG_01942":null,"SJAG_02026":null,"SJAG_02244":null,"SJAG_02592":null,"SJAG_02638":null,"SJAG_03048":null,"SJAG_03501":null,"SJAG_03869":null,"SJAG_04291":null,"SJAG_05000":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of protein metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0032269"],"synonyms":[{"name":"down regulation of cellular protein metabolic process","type":"exact"},{"name":"down regulation of protein metabolic process","type":"exact"},{"name":"down-regulation of cellular protein metabolic process","type":"exact"},{"name":"down-regulation of protein metabolic process","type":"exact"},{"name":"downregulation of cellular protein metabolic process","type":"exact"},{"name":"downregulation of protein metabolic process","type":"exact"},{"name":"inhibition of cellular protein metabolic process","type":"narrow"},{"name":"inhibition of protein metabolic process","type":"narrow"},{"name":"negative regulation of cellular protein metabolic process","type":"exact"},{"name":"negative regulation of cellular protein metabolism","type":"exact"},{"name":"negative regulation of protein metabolism","type":"exact"}],"termid":"GO:0051248","terms_by_termid":{"GO:0032435":null,"GO:0141014":null,"GO:1904293":null,"GO:1904689":null,"GO:1905785":null,"GO:1990625":null,"GO:2000766":null,"GO:2001125":null}}


id: GO:0010275
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool.","definition_xrefs":["GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0065003"],"is_obsolete":false,"name":"NAD(P)H dehydrogenase complex assembly","synonyms":[{"name":"NAD(P)H dehydrogenase complex (plastoquinone) assembly","type":"narrow"}],"termid":"GO:0010275"}


id: PBO:0086247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that may have a role in transcription elongation; forms a complex with Csn12p that is recruited to transcribed genes; possibly involved in splicing based on pre-mRNA accumulation defect for many intron-containing genes","termid":"PBO:0086247"}


id: MONDO:0971080
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Grisel syndrome","secondary_identifiers":["UMLS:C0263885","MEDGEN:538169","Orphanet:662255"],"termid":"MONDO:0971080","xrefs":{"Monarch":{"xref_id":"0971080"}}}


id: MONDO:0000468
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder characterized by an electrocardiographic finding of complete failure of atrial electrical impulse conduction to the ventricles. This is manifested on the ECG by disassociation of atrial and ventricular rhythms. The atrial rate must be faster than the ventricular rate. (CDISC)","definition_xrefs":["NCIT:C50501"],"direct_ancestors":[{"relation_name":"is_a","term_name":"atrioventricular block","termid":"MONDO:0000465"},{"relation_name":"is_a","term_name":"cardiac rhythm disease","termid":"MONDO:0007263"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"third-degree atrioventricular block","secondary_identifiers":["ICD9:426.0","DOID:0050823","NANDO:2200214","SCTID:27885002","UMLS:C0151517","MEDGEN:56230"],"synonyms":[{"name":"AV block third degree","type":"exact"},{"name":"atrioventricular block complete","type":"exact"},{"name":"atrioventricular block, third degree","type":"exact"},{"name":"complete AV block","type":"exact"},{"name":"complete atrioventricular block","type":"exact"},{"name":"complete heart block","type":"exact"},{"name":"non-congenital complete atrioventricular block","type":"exact"},{"name":"third degree AV block","type":"exact"},{"name":"third degree atrioventricular block","type":"exact"}],"termid":"MONDO:0000468","xrefs":{"Monarch":{"xref_id":"0000468"}}}


id: PBO:0039548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ANKRD44 antisense RNA 1","termid":"PBO:0039548"}


id: PBO:0109606
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 90 member A13","termid":"PBO:0109606"}


id: SO:0001966
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A modified DNA cytosine base feature, modified by a carboxy group at the 5 carbon.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified_cytosine","termid":"SO:0001963"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5_carboxylcytosine","secondary_identifiers":["http:http\\://www.pacificbiosciences.com/pdf/WP_Detecting_DNA_Base_Modifications_Using_SMRT_Sequencing.pdf"],"synonyms":[{"name":"5-caC","type":"exact"},{"name":"5-carboxycytosine","type":"exact"}],"termid":"SO:0001966"}


id: PBO:0065056
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRELI domain containing 3B pseudogene 10","termid":"PBO:0065056"}


id: PR:Q9UT39
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A WD repeat-containing protein 82 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00689","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized WD repeat-containing protein C824.04 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC824.04","secondary_identifiers":["UniProtKB:Q9UT39"],"synonyms":[{"name":"Spom972h-WDR82","type":"exact"}],"termid":"PR:Q9UT39"}


id: PBO:0034630
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_to_nuclear_envelope_during_G0_to_G1_transition","termid":"PBO:0034630"}


id: GO:0004239
data:
  {"annotated_genes":["SJAG_02033","SJAG_06636"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[62171,63549],"is_not":false,"summary":null,"term":"GO:0004239"}]},"cv_name":"molecular_function","definition":"Catalysis of the release of N-terminal initiator methionine from peptides.","definition_xrefs":["EC:3.4.11.18"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminopeptidase activity","termid":"GO:0004177"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02033":null,"SJAG_06636":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0008233"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0008233","GO:0003824","GO:0140096"],"is_obsolete":false,"name":"initiator methionyl aminopeptidase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["MetaCyc:3.4.11.18-RXN"],"synonyms":[{"name":"L-methionine aminopeptidase activity","type":"related"},{"name":"MAP","type":"related"},{"name":"methionine aminopeptidase activity","type":"related"},{"name":"peptidase M activity","type":"related"}],"termid":"GO:0004239","terms_by_termid":{"GO:0004239":null}}


id: GO:0036039
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving the polyphenol, curcumin.","definition_xrefs":["PMID:21467222"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ether metabolic process","termid":"GO:0018904"},{"relation_name":"is_a","term_name":"phenol-containing compound metabolic process","termid":"GO:0018958"},{"relation_name":"is_a","term_name":"ketone metabolic process","termid":"GO:0042180"},{"relation_name":"is_a","term_name":"olefinic compound metabolic process","termid":"GO:0120254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"curcumin metabolic process","synonyms":[{"name":"(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process","type":"exact"},{"name":"(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism","type":"exact"},{"name":"curcumin metabolism","type":"exact"},{"name":"diferuloylmethane metabolic process","type":"exact"},{"name":"diferuloylmethane metabolism","type":"exact"},{"name":"turmeric yellow metabolic process","type":"exact"},{"name":"turmeric yellow metabolism","type":"exact"}],"termid":"GO:0036039"}


id: PBO:0053785
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1036","termid":"PBO:0053785"}


id: MONDO:0008988
data:
  {"annotated_genes":["SJAG_04577"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86831],"is_not":false,"summary":null,"term":"MONDO:0008988"}]},"cv_name":"mondo","definition":"Citrullinemia type I is a rare autosomal recessive urea cycle defect characterized biologically by hyperammonemia and clinically by progressive lethargy, poor feeding and vomiting in the neonatal form (Acute neonatal citrullinemia type I) and by variable hyperammonemia in the later-onset form (adult-onset citrullinemia type I).","definition_xrefs":["Orphanet:247525"],"direct_ancestors":[{"relation_name":"is_a","term_name":"citrullinemia","termid":"MONDO:0015991"},{"relation_name":"is_a","term_name":"urea cycle disorder or inherited hyperammonemia","termid":"MONDO:0800153"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04577":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"citrullinemia type I","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1648491","NANDO:2200480","NCIT:C150601","UMLS:C4721769","OMIM:215700","SCTID:398680004","NANDO:1200805","MedDRA:10058298","GARD:6114","DOID:0070340"],"synonyms":[{"name":"ASS deficiency","type":"exact"},{"name":"CTLN1","type":"exact"},{"name":"CTNL1","type":"related"},{"name":"Citrullinuria","type":"related"},{"name":"argininosuccinate synthase deficiency","type":"exact"},{"name":"argininosuccinate synthetase deficiency","type":"exact"},{"name":"argininosuccinic acid synthase deficiency","type":"exact"},{"name":"argininosuccinic acid synthetase deficiency","type":"exact"},{"name":"citrullinemia","type":"broad"},{"name":"citrullinemia 1","type":"related"},{"name":"citrullinemia type 1","type":"exact"},{"name":"citrullinemia type I","type":"exact"},{"name":"citrullinemia, classic","type":"related"},{"name":"citrullinemia, type 1","type":"related"},{"name":"classic citrullinemia","type":"exact"}],"termid":"MONDO:0008988","terms_by_termid":{"MONDO:0008988":null},"xrefs":{"Monarch":{"xref_id":"0008988"}}}


id: FYPO:0002312
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to ionizing radiation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"resistance to stress during vegetative growth","termid":"FYPO:0000850"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000139","FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"resistance to ionizing radiation during vegetative growth","synonyms":[{"name":"increased vegetative cell population growth during cellular response to ionizing radiation","type":"exact"},{"name":"resistance to gamma irradiation during vegetative growth","type":"narrow"},{"name":"resistance to gamma radiation during vegetative growth","type":"narrow"},{"name":"resistance to ionizing radiation during mitotic cell cycle","type":"related"},{"name":"resistant to IR during vegetative growth","type":"exact"},{"name":"resistant to ionizing radiation during vegetative growth","type":"exact"}],"termid":"FYPO:0002312"}


id: MONDO:0800485
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any overgrowth syndrome where the cause of the disease is a gain-of-function variant in the AKT3 gene.","definition_xrefs":["PMID:28969385"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"overgrowth syndrome","termid":"MONDO:0019716"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AKT3-related overgrowth spectrum","termid":"MONDO:0800485","xrefs":{"Monarch":{"xref_id":"0800485"}}}


id: PBO:0003868
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TIM22 inner membrane protein import complex anchor subunit Tim18","termid":"PBO:0003868"}


id: GO:0021941
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation.","definition_xrefs":["GOC:jid","PMID:15157725","GOC:cls","GOC:dph","GO_REF:0000021","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cerebellar granule cell precursor proliferation","termid":"GO:0021936"},{"relation_name":"is_a","term_name":"negative regulation of neural precursor cell proliferation","termid":"GO:2000178"},{"relation_name":"negatively_regulates","term_name":"cerebellar granule cell precursor proliferation","termid":"GO:0021930"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cerebellar granule cell precursor proliferation","synonyms":[{"name":"down regulation of granule cell precursor proliferation","type":"exact"},{"name":"down-regulation of granule cell precursor proliferation","type":"exact"},{"name":"downregulation of granule cell precursor proliferation","type":"exact"},{"name":"inhibition of granule cell precursor proliferation","type":"narrow"}],"termid":"GO:0021941"}


id: GO:0009261
data:
  {"annotated_genes":["SJAG_03903","SJAG_02107","SJAG_03676","SJAG_00027","SJAG_00839","SJAG_02009","SJAG_02945","SJAG_04048","SJAG_04870","SJAG_04192","SJAG_02135","SJAG_03660","SJAG_03828","SJAG_01310","SJAG_02481","SJAG_06621","SJAG_00461","SJAG_02369","SJAG_00685","SJAG_03373","SJAG_06622","SJAG_05314","SJAG_02785","SJAG_02796","SJAG_00605","SJAG_04334","SJAG_04495"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[78973],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901911"},{"annotations":[116120],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006198"},{"annotations":[103136,109141,109142,109145,109144,109146,94773,109143,116092,103393,94284,77638,109147,105587,97749,105217,105218,105588,105219,98022],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061621"},{"annotations":[88367],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061613"},{"annotations":[72857,75818],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0045820"},{"annotations":[69868],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0006110"},{"annotations":[76058],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006256"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide catabolic process","termid":"GO:0009166"},{"relation_name":"is_a","term_name":"ribonucleotide metabolic process","termid":"GO:0009259"},{"relation_name":"is_a","term_name":"carbohydrate derivative catabolic process","termid":"GO:1901136"}],"gene_count":27,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00461":null,"SJAG_00605":null,"SJAG_00685":null,"SJAG_00839":null,"SJAG_01310":null,"SJAG_02009":null,"SJAG_02107":null,"SJAG_02135":null,"SJAG_02369":null,"SJAG_02481":null,"SJAG_02785":null,"SJAG_02796":null,"SJAG_02945":null,"SJAG_03373":null,"SJAG_03660":null,"SJAG_03676":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04048":null,"SJAG_04192":null,"SJAG_04334":null,"SJAG_04495":null,"SJAG_04870":null,"SJAG_05314":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"ribonucleotide catabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"ribonucleotide breakdown","type":"exact"},{"name":"ribonucleotide catabolism","type":"exact"},{"name":"ribonucleotide degradation","type":"exact"}],"termid":"GO:0009261","terms_by_termid":{"GO:0006110":null,"GO:0006198":null,"GO:0006256":null,"GO:0045820":null,"GO:0061613":null,"GO:0061621":null,"GO:1901911":null}}


id: PBO:0088674
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arrestin-related substrate adaptor Rod1","termid":"PBO:0088674"}


id: GO:0033001
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.","definition_xrefs":["PMID:11244038","PMID:12413532","GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Fc receptor complex","termid":"GO:0032997"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005886","GO:0032991"],"is_obsolete":false,"name":"Fc-gamma receptor III complex","synonyms":[{"name":"FcgRIII complex","type":"exact"},{"name":"IgG receptor complex","type":"broad"},{"name":"immunoglobulin G receptor complex","type":"broad"}],"termid":"GO:0033001"}


id: MONDO:0022859
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A congenital anatomic anomaly in which the heart has only two chambers.","definition_xrefs":["NCIT:C124591"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart disorder","termid":"MONDO:0005267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"cor biloculare","secondary_identifiers":["SCTID:81990004","UMLS:C0152238","ICD9:745.7","MEDGEN:56271"],"synonyms":[{"name":"Cor Biloculare","type":"exact"},{"name":"TWO-chambered heart","type":"exact"},{"name":"absence of atrial and ventricular septa","type":"related"},{"name":"cor biloculare","type":"exact"}],"termid":"MONDO:0022859","xrefs":{"Monarch":{"xref_id":"0022859"}}}


id: PBO:0069859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1146, pseudogene","termid":"PBO:0069859"}


id: GO:0080146
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.","definition_xrefs":["MetaCyc:LCYSDESULF-RXN","PMID:19955263"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-sulfur lyase activity","termid":"GO:0016846"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016829","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"L-cysteine desulfhydrase activity","secondary_identifiers":["Reactome:R-HSA-1614591","Reactome:R-HSA-1614614","RHEA:24931"],"termid":"GO:0080146"}


id: PBO:0091348
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human DBR1","termid":"PBO:0091348"}


id: PBO:0038307
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA_degradation","termid":"PBO:0038307"}


id: PR:Q10088
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC11D3.09 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10088"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"agmatinase 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC11D3.09","synonyms":[{"name":"AUH 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-SPAC11D3.09","type":"exact"},{"name":"agmatine ureohydrolase 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10088"}


id: GO:0047339
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate.","definition_xrefs":["EC:2.7.7.28","MetaCyc:2.7.7.28-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotidyltransferase activity","termid":"GO:0016779"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016779"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016779","GO:0016740"],"is_obsolete":false,"name":"nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity","secondary_identifiers":["GO:0047340"],"synonyms":[{"name":"GDP hexose pyrophosphorylase activity","type":"narrow"},{"name":"GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity","type":"narrow"},{"name":"GTP:hexose-1-phosphate guanylyltransferase activity","type":"narrow"},{"name":"NDP hexose pyrophosphorylase activity","type":"related"},{"name":"NDP-hexose diphosphorylase activity","type":"exact"},{"name":"NDP-hexose pyrophosphorylase activity","type":"exact"},{"name":"NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity","type":"related"},{"name":"NTP:hexose-1-phosphate nucleotidyltransferase activity","type":"related"},{"name":"guanosine diphosphohexose pyrophosphorylase activity","type":"narrow"},{"name":"hexose 1-phosphate guanylyltransferase activity","type":"related"},{"name":"hexose 1-phosphate nucleotidyltransferase activity","type":"related"},{"name":"hexose nucleotidylating enzyme activity","type":"related"},{"name":"hexose-1-phosphate guanylyltransferase activity","type":"narrow"},{"name":"nucleoside diphosphohexose pyrophosphorylase activity","type":"related"},{"name":"nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity","type":"related"}],"termid":"GO:0047339"}


id: GO:0002920
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of a humoral immune response.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune response","termid":"GO:0050776"},{"relation_name":"regulates","term_name":"humoral immune response","termid":"GO:0006959"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of humoral immune response","termid":"GO:0002920"}


id: PBO:0054657
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2063","termid":"PBO:0054657"}


id: MONDO:0030859
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"COACH syndrome","termid":"MONDO:0100349"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0006025"],"is_obsolete":false,"name":"COACH syndrome 2","secondary_identifiers":["UMLS:C5436837","GARD:16422","MEDGEN:1752166","OMIM:619111"],"synonyms":[{"name":"COACH2","type":"exact"}],"termid":"MONDO:0030859","xrefs":{"Monarch":{"xref_id":"0030859"}}}


id: FYPO:0000924
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of anisomycin than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0000003","FYPO:0005447","FYPO:0001985","FYPO:0002682"],"is_obsolete":false,"name":"resistance to anisomycin","synonyms":[{"name":"resistance to anisomycin during mitotic cell cycle","type":"related"},{"name":"resistance to anisomycin during vegetative growth","type":"exact"},{"name":"resistant to anisomycin","type":"exact"}],"termid":"FYPO:0000924"}


id: GO:0015038
data:
  {"annotated_genes":["SJAG_01417","SJAG_01292","SJAG_04632","SJAG_01162","SJAG_02495","SJAG_00822"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[62175,67027,73478,75416,78295],"is_not":false,"summary":null,"term":"GO:0015038"},{"annotations":[78837],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004362"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disulfide oxidoreductase activity","termid":"GO:0015036"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00822":null,"SJAG_01162":null,"SJAG_01292":null,"SJAG_01417":null,"SJAG_02495":null,"SJAG_04632":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0015036"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0015036","GO:0003824"],"is_obsolete":false,"name":"glutathione disulfide oxidoreductase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000117":null},"secondary_identifiers":["Reactome:R-HSA-111746"],"synonyms":[{"name":"glutaredoxin","type":"broad"},{"name":"glutathione disulphide oxidoreductase activity","type":"exact"},{"name":"glutathione oxidoreductase activity","type":"broad"}],"termid":"GO:0015038","terms_by_termid":{"GO:0004362":null,"GO:0015038":null}}


id: PBO:0036324
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase assembly factor Coa2 (predicted)","termid":"PBO:0036324"}


id: PBO:0045317
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deoxynucleotidyltransferase terminal interacting protein 2","termid":"PBO:0045317"}


id: GO:1904239
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","GOC:PARL","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein-containing complex assembly","termid":"GO:0043254"},{"relation_name":"regulates","term_name":"VCP-NPL4-UFD1 AAA ATPase complex assembly","termid":"GO:1904210"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly","synonyms":[{"name":"regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly","type":"narrow"},{"name":"regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation","type":"narrow"},{"name":"regulation of VCP-NPL4-UFD1 AAA ATPase complex formation","type":"exact"},{"name":"regulation of p97-Ufd1-Npl4 complex assembly","type":"exact"},{"name":"regulation of p97-Ufd1-Npl4 complex formation","type":"exact"}],"termid":"GO:1904239"}


id: PBO:0055735
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leiomodin 1","termid":"PBO:0055735"}


id: PBO:0040520
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-2-glycoprotein 1, zinc-binding","termid":"PBO:0040520"}


id: PBO:0086278
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with a potential role in cell survival pathways; required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis; mutant has increased aneuploidy tolerance","termid":"PBO:0086278"}


id: PBO:0012241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial pyrimidine nucleotide transporter (predicted)","termid":"PBO:0012241"}


id: PR:O14111
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- psd3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O14111"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylserine decarboxylase proenzyme 3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC31G5.15","synonyms":[{"name":"Spom972h-psd3","type":"exact"}],"termid":"PR:O14111"}


id: PBO:0086567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; conserved among S. cerevisiae strains; YOR015W is not an essential gene","termid":"PBO:0086567"}


id: GO:0051231
data:
  {"annotated_genes":["SJAG_02761","SJAG_00794","SJAG_01297","SJAG_02336","SJAG_00930","SJAG_00244","SJAG_03073","SJAG_04003","SJAG_03540","SJAG_02624","SJAG_01224","SJAG_00082","SJAG_04841","SJAG_04464","SJAG_01215","SJAG_04745","SJAG_03048","SJAG_00773","SJAG_04597","SJAG_01613","SJAG_02246"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[95067,75471,77484],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000073"},{"annotations":[101189],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051232"},{"annotations":[117892,118406,107180],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000022"},{"annotations":[100143,94532,103299],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061805"},{"annotations":[108015,97043,100144,103654,98381,101195,99616],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061804"},{"annotations":[94534,98993,76824,108610,97044],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051256"},{"annotations":[102121],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:1902845"},{"annotations":[94173,89762],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1902846"},{"annotations":[110766],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0032888"},{"annotations":[114793],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0110162"}]},"cv_name":"biological_process","definition":"The cell cycle process in which the distance is lengthened between poles of the spindle.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule-based process","termid":"GO:0007017"},{"relation_name":"is_a","term_name":"cell cycle process","termid":"GO:0022402"},{"relation_name":"part_of","term_name":"spindle organization","termid":"GO:0007051"},{"relation_name":"part_of","term_name":"nuclear chromosome segregation","termid":"GO:0098813"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_00244":null,"SJAG_00773":null,"SJAG_00794":null,"SJAG_00930":null,"SJAG_01215":null,"SJAG_01224":null,"SJAG_01297":null,"SJAG_01613":null,"SJAG_02246":null,"SJAG_02336":null,"SJAG_02624":null,"SJAG_02761":null,"SJAG_03048":null,"SJAG_03073":null,"SJAG_03540":null,"SJAG_04003":null,"SJAG_04464":null,"SJAG_04597":null,"SJAG_04745":null,"SJAG_04841":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0000226"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0007010"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0000226","GO:0007010"],"is_obsolete":false,"name":"spindle elongation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0051231","terms_by_termid":{"GO:0000022":null,"GO:0000073":null,"GO:0032888":null,"GO:0051232":null,"GO:0051256":null,"GO:0061804":null,"GO:0061805":null,"GO:0110162":null,"GO:1902845":null,"GO:1902846":null}}


id: MONDO:0008879
data:
  {"annotated_genes":["SJAG_02024"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85347],"is_not":false,"summary":null,"term":"MONDO:0008879"}]},"cv_name":"mondo","definition":"Bowen-Conradi syndrome (BCS) is a lethal autosomal recessive ribosomal biogenesis disorder characterized by severe prenatal and postnatal growth retardation, microcephaly, a distinctive facial appearance, extreme psychomotor delay, hip and knee contractures and rockerbottom feet.","definition_xrefs":["Orphanet:1270"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02024":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Bowen-Conradi syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:211180","NORD:869","GARD:5950","UMLS:C1859405","MESH:C537081","MEDGEN:349160","SCTID:711153001","icd11.foundation:1713786719","DOID:0050684","ICD9:759.89"],"synonyms":[{"name":"BWCNS","type":"exact"},{"name":"Bowen Hutterite Syndrome","type":"exact"},{"name":"Bowen Hutterite syndrome","type":"exact"},{"name":"Bowen Hutterite syndrome (formerly)","type":"exact"},{"name":"Bowen Hutterite syndrome, formerly","type":"exact"},{"name":"Bowen syndrome, Hutterite type","type":"exact"},{"name":"Bowen-Conradi Hutterite syndrome","type":"exact"},{"name":"Bowen-Conradi syndrome","type":"exact"}],"termid":"MONDO:0008879","terms_by_termid":{"MONDO:0008879":null},"xrefs":{"Monarch":{"xref_id":"0008879"}}}


id: GO:0140567
data:
  {"annotated_genes":["SJAG_04203","SJAG_01435"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[100777,116050],"is_not":false,"summary":null,"term":"GO:0140567"}]},"cv_name":"molecular_function","definition":"The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. The reaction is driven by ATP hydrolysis.","definition_xrefs":["PMID:24821790","PMID:28712723","PMID:32973005"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein transporter activity","termid":"GO:0140318"},{"relation_name":"is_a","term_name":"ATP-dependent activity","termid":"GO:0140657"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01435":null,"SJAG_04203":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140318"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0140318","GO:0003674"],"is_obsolete":false,"name":"membrane protein dislocase activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"transmembrane helix dislocasentransmembrane protein dislocase activity","type":"related"}],"termid":"GO:0140567","terms_by_termid":{"GO:0140567":null}}


id: PBO:0057396
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 548f-4","termid":"PBO:0057396"}


id: MONDO:0011961
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary sensory and autonomic neuropathy, type 1B (HSAN1B) is characterized by the association of type 1 HSAN with paroxysmal cough and gastroesophageal reflux (GOR).","definition_xrefs":["Orphanet:139564"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary sensory and autonomic neuropathy type 1","termid":"MONDO:0018213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002525","MONDO:0005244"],"is_obsolete":false,"name":"hereditary sensory and autonomic neuropathy type 1B","secondary_identifiers":["GARD:16958","OMIM:608088","PMID:12870133","MEDGEN:330880","PMID:16311270","SCTID:717825008","UMLS:C1842586","MESH:C564296","DOID:0070148"],"synonyms":[{"name":"HSAN with cough and gastroesophageal reflux","type":"exact"},{"name":"HSAN1B","type":"exact"},{"name":"hereditary sensory and autonomic neuropathy type 1 with cough and gastroesophageal reflux","type":"exact"},{"name":"hereditary sensory and autonomic neuropathy type IB","type":"exact"},{"name":"hereditary sensory neuropathy type 1B","type":"related"},{"name":"hereditary sensory neuropathy type IB","type":"exact"},{"name":"neuropathy, hereditary sensory and autonomic, type 1B","type":"related"},{"name":"neuropathy, hereditary sensory and autonomic, type I, with cough and gastroesophageal reflux","type":"related"},{"name":"neuropathy, hereditary sensory, type 1B","type":"related"},{"name":"neuropathy, hereditary sensory, type IB","type":"exact"}],"termid":"MONDO:0011961","xrefs":{"Monarch":{"xref_id":"0011961"}}}


id: PBO:0084839
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; also involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress","termid":"PBO:0084839"}


id: PBO:0005850
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPX/EXS domain protein (predicted)","termid":"PBO:0005850"}


id: MONDO:0006060
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A squamous cell carcinoma that arises from the nasopharynx.","direct_ancestors":[{"relation_name":"is_a","term_name":"head and neck squamous cell carcinoma","termid":"MONDO:0010150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"nasopharyngeal squamous cell carcinoma","secondary_identifiers":["NCIT:C167265","NCIT:C3871","EFO:1000058","MEDGEN:76017","MESH:C538339","UMLS:C0279698"],"termid":"MONDO:0006060","xrefs":{"Monarch":{"xref_id":"0006060"}}}


id: PBO:0000589
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcineurin responsive transcription factor Prz1","termid":"PBO:0000589"}


id: MONDO:0007999
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare disorder characterized by the partial separation of the cerebral hemispheres. It is associated with mutations in the SIX3 gene.","definition_xrefs":["NCIT:C74995"],"direct_ancestors":[{"relation_name":"is_a","term_name":"holoprosencephaly","termid":"MONDO:0016296"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"holoprosencephaly 2","secondary_identifiers":["OMIM:157170","MEDGEN:322517","UMLS:C1834877","MESH:C563579","DOID:0110872"],"synonyms":[{"name":"HPE2","type":"exact"},{"name":"SIX3 holoprosencephaly","type":"exact"},{"name":"holoprosencephaly 2","type":"exact"},{"name":"holoprosencephaly caused by mutation in SIX3","type":"exact"},{"name":"holoprosencephaly type 2","type":"exact"}],"termid":"MONDO:0007999","xrefs":{"Monarch":{"xref_id":"0007999"}}}


id: FYPO:0004822
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal in ribosomal DNA regions.","definition_xrefs":["PMID:25417108","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased number of R-loops","termid":"FYPO:0007901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"increased number of R-loops at rDNA","synonyms":[{"name":"increased RNA-DNA hybrid level at rDNA","type":"exact"},{"name":"increased level of DNA:RNA hybrids at rDNA","type":"exact"},{"name":"increased level of RNA-DNA hybrids at rDNA","type":"exact"},{"name":"increased level of RNA-DNA hybrids at rDNA during mitotic cell cycle","type":"related"},{"name":"increased level of RNA-DNA hybrids at rDNA during vegetative growth","type":"exact"}],"termid":"FYPO:0004822"}


id: PBO:0067156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 208, pseudogene","termid":"PBO:0067156"}


id: PBO:0031328
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_cisplatin","termid":"PBO:0031328"}


id: PBO:0044554
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dual adaptor of phosphotyrosine and 3-phosphoinositides 1","termid":"PBO:0044554"}


id: PBO:0029293
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_protein_localization_to_nucleus_during_meiosis","termid":"PBO:0029293"}


id: PBO:0046331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ENOX1 antisense RNA 1","termid":"PBO:0046331"}


id: MONDO:0009212
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterized by mild to severe bleeding symptoms.","definition_xrefs":["Orphanet:328"],"direct_ancestors":[{"relation_name":"is_a","term_name":"factor X deficiency","termid":"MONDO:0002247"},{"relation_name":"is_a","term_name":"congenital vitamin K-dependent coagulation factors deficiency","termid":"MONDO:0015722"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"congenital factor X deficiency","secondary_identifiers":["icd11.foundation:1886781445","DOID:2222","OMIM:227600","ICD9:286.3","MEDGEN:543976","GARD:6404","UMLS:C0272327","SCTID:37350004","NCIT:C98940"],"synonyms":[{"name":"F10 deficiency","type":"related"},{"name":"Stuart factor deficiency, congenital","type":"related"},{"name":"Stuart-Prower Factor deficiency","type":"related"},{"name":"Stuart-Prower factor deficiency","type":"exact"},{"name":"congenital Stuart factor deficiency","type":"exact"},{"name":"congenital factor X deficiency","type":"exact"},{"name":"disease, Stuart-Prower","type":"exact"},{"name":"factor 10 deficiency","type":"related"},{"name":"factor X deficiency","type":"related"},{"name":"factor X deficiency, congenital","type":"related"},{"name":"hereditary Factor X deficiency","type":"exact"}],"termid":"MONDO:0009212","xrefs":{"Monarch":{"xref_id":"0009212"}}}


id: MONDO:0850230
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An urticaria that is characterized by the presence of urticaria for a period exceeding 6 weeks, assuming symptoms for most days of the week.","definition_xrefs":["DOID:0080747"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urticaria","termid":"MONDO:0005492"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"chronic urticaria","secondary_identifiers":["MEDGEN:537829","UMLS:C0263338","icd11.foundation:901000137"],"termid":"MONDO:0850230","xrefs":{"Monarch":{"xref_id":"0850230"}}}


id: PBO:0117026
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lncRNA regulator of PLAAT3 mediated phospholipid metabolism","termid":"PBO:0117026"}


id: PBO:0054755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2166","termid":"PBO:0054755"}


id: GO:0004708
data:
  {"annotated_genes":["SJAG_02342","SJAG_01181","SJAG_00993"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71243,74211,75922],"is_not":false,"summary":null,"term":"GO:0004708"}]},"cv_name":"molecular_function","definition":"Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a T-X-Y motif in the activation loop of a MAP kinase (MAPK) substrate.","definition_xrefs":["PMID:38270553","PMID:12623839"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein serine/threonine/tyrosine kinase activity","termid":"GO:0004712"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00993":null,"SJAG_01181":null,"SJAG_02342":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0004672"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0004672","GO:0016740","GO:0016301","GO:0140096"],"is_obsolete":false,"name":"MAP kinase kinase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-5218804","Reactome:R-HSA-450333","Reactome:R-HSA-1247960","Reactome:R-HSA-3238999","EC:2.7.12.2","MetaCyc:2.7.12.2-RXN","Reactome:R-HSA-448951"],"synonyms":[{"name":"ATP:protein phosphotransferase (MAPKKK-activated) activity","type":"related"},{"name":"ERK activator kinase activity","type":"exact"},{"name":"MAP kinase kinase 4 activity","type":"narrow"},{"name":"MAP kinase kinase 7 activity","type":"narrow"},{"name":"MAP kinase or ERK kinase activity","type":"related"},{"name":"MAP2K","type":"related"},{"name":"MAPK activator activity","type":"exact"},{"name":"MAPKK","type":"related"},{"name":"MAPKK activity","type":"exact"},{"name":"MAPKK1","type":"related"},{"name":"MEK activity","type":"broad"},{"name":"MEK1","type":"related"},{"name":"MEK2","type":"related"},{"name":"MKK","type":"related"},{"name":"MKK2","type":"related"},{"name":"MKK4","type":"related"},{"name":"MKK6","type":"related"},{"name":"MKK7","type":"related"},{"name":"STK27","type":"related"},{"name":"mitogen-activated protein kinase kinase activity","type":"related"}],"termid":"GO:0004708","terms_by_termid":{"GO:0004708":null}}


id: MONDO:0014214
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An asphyxiating thoracic dystrophy that has material basis in compound heterozygous mutation in the WDR60 gene on chromosome 7q36.","definition_xrefs":["DOID:0110094","PMID:23910462"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"asphyxiating thoracic dystrophy 3","termid":"MONDO:0013127"},{"relation_name":"is_a","term_name":"Jeune syndrome","termid":"MONDO:0018770"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"short-rib thoracic dysplasia 8 with or without polydactyly","secondary_identifiers":["UMLS:C3809691","MEDGEN:816021","GARD:15975","OMIM:615503"],"synonyms":[{"name":"SRPS6","type":"exact"},{"name":"SRTD8","type":"exact"},{"name":"short rib-polydactyly syndrome type VI","type":"exact"},{"name":"short rib-polydactyly syndrome, type 6","type":"related"},{"name":"short-rib thoracic dysplasia 8 with or without polydactyly","type":"exact"}],"termid":"MONDO:0014214","xrefs":{"Monarch":{"xref_id":"0014214"}}}


id: MONDO:0009842
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autoinflammatory disease with defective neutrophil function caused by a homozygous Arg219His mutation in the transcription factor C/EBPε.","definition_xrefs":["PMID:31201888"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoinflammatory syndrome","termid":"MONDO:0019751"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pelger-Huet-like anomaly and episodic fever with abdominal pain","secondary_identifiers":["UMLS:C1850054","MESH:C564899","OMIM:260570","MEDGEN:376692"],"synonyms":[{"name":"Pelger-Huet-like anomaly and episodic fever with abdominal pain","type":"exact"},{"name":"immunodeficiency 108 with autoinflammation","type":"exact"}],"termid":"MONDO:0009842","xrefs":{"Monarch":{"xref_id":"0009842"}}}


id: PBO:0081765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 696","termid":"PBO:0081765"}


id: MONDO:0010321
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autism, susceptiblity to","termid":"MONDO:0020836"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autism, susceptibility to, X-linked 1","secondary_identifiers":["MEDGEN:335205","OMIM:300425","UMLS:C1845540"],"synonyms":[{"name":"AUTSX1","type":"related"},{"name":"autism susceptibility, X-linked 1","type":"exact"},{"name":"autism, susceptibility to, X-linked 1","type":"exact"},{"name":"autism, susceptibility to, X-linked type 1","type":"exact"},{"name":"susceptibility to X-linked autism 1","type":"related"}],"termid":"MONDO:0010321","xrefs":{"Monarch":{"xref_id":"0010321"}}}


id: GO:0070121
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"Kupffer's vesicle development","synonyms":[{"name":"KV development","type":"exact"}],"termid":"GO:0070121"}


id: PBO:0047127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FAM169A antisense RNA 1","termid":"PBO:0047127"}


id: PBO:0066462
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA exonuclease 5","termid":"PBO:0066462"}


id: GO:0032009
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.","definition_xrefs":["PMID:12388753","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phagocytic vesicle","termid":"GO:0045335"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0031410","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"early phagosome","synonyms":[{"name":"early phagocytic vesicle","type":"exact"}],"termid":"GO:0032009"}


id: GO:0047406
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-D-glucosamine + L-asparagine.","definition_xrefs":["EC:3.2.2.11","RHEA:12324"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing N-glycosyl compounds","termid":"GO:0016799"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016798"}],"interesting_parent_ids":["GO:0016798","GO:0003824","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"beta-aspartyl-N-acetylglucosaminidase activity","secondary_identifiers":["KEGG_REACTION:R01266","MetaCyc:3.2.2.11-RXN"],"synonyms":[{"name":"1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity","type":"related"},{"name":"beta-aspartylacetylglucosaminidase activity","type":"related"}],"termid":"GO:0047406"}


id: PBO:0031870
data:
  {"annotation_feature_type":"gene","cv_name":"species_dist","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved in Fungi","termid":"PBO:0031870"}


id: GO:0090442
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.","definition_xrefs":["GOC:dph","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete trehalose catabolism in response to heat stress (obsolete GO:0090442)","synonyms":[{"name":"trehalose catabolic process in response to heat stress","type":"exact"}],"termid":"GO:0090442"}


id: MONDO:0002870
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The backflow of blood from the right ventricle into the right atrium, owning to imperfect functioning/insufficiency of the tricuspid valve.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tricuspid valve disorder","termid":"MONDO:0000471"},{"relation_name":"is_a","term_name":"vascular insufficiency disorder","termid":"MONDO:0020674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"tricuspid valve insufficiency","secondary_identifiers":["NANDO:2200301","UMLS:C0040961","MEDGEN:11911","NCIT:C50842","DOID:4080","MESH:D014262","icd11.foundation:770887951","SCTID:111287006"],"synonyms":[{"name":"insufficiency, tricuspid","type":"exact"},{"name":"tricuspid incompetence","type":"exact"},{"name":"tricuspid insufficiency","type":"exact"},{"name":"tricuspid regurgitation","type":"exact"},{"name":"tricuspid valve regurgitation","type":"exact"}],"termid":"MONDO:0002870","xrefs":{"Monarch":{"xref_id":"0002870"}}}


id: PBO:0014244
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Overexpressed in BFA Resistant strains","termid":"PBO:0014244"}


id: MONDO:0800174
data:
  {"annotated_genes":["SJAG_01013","SJAG_01433"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87100],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030334"},{"annotations":[87130],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032742"}]},"cv_name":"mondo","definition":"An inherited susceptibility or predisposition to developing encephalitis, acute, infection-induced.","definition_xrefs":["MONDO:patterns/inherited_susceptibility"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01013":null,"SJAG_01433":null},"genotype_count":0,"is_obsolete":false,"name":"encephalitis, acute, infection-induced, susceptibility to","references_by_uniquename":{"PB_REF:0000006":null},"termid":"MONDO:0800174","terms_by_termid":{"MONDO:0030334":null,"MONDO:0032742":null},"xrefs":{"Monarch":{"xref_id":"0800174"}}}


id: MONDO:0015783
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Prader-Willi syndrome due to paternal 15q11q13 deletion","termid":"MONDO:0020301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0700092"],"is_obsolete":false,"name":"Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1","secondary_identifiers":["Orphanet:177901","UMLS:C5680507","GARD:20138","DECIPHER:14","MEDGEN:1826083"],"synonyms":[{"name":"Prader-Willi syndrome (Type 1)","type":"exact"}],"termid":"MONDO:0015783","xrefs":{"Monarch":{"xref_id":"0015783"}}}


id: PBO:0041938
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CBX3 pseudogene 6","termid":"PBO:0041938"}


id: MONDO:0012806
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"ectodermal dysplasia and immune deficiency","termid":"MONDO:0010293"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005046"],"is_obsolete":false,"name":"ectodermal dysplasia and immunodeficiency 2","secondary_identifiers":["UMLS:C2677481","GARD:15542","MESH:C567411","NCIT:C176826","OMIM:612132","DOID:0081079","MEDGEN:394295"],"synonyms":[{"name":"EPAID2","type":"exact"},{"name":"ectodermal dysplasia, anhidrotic, with T-cell immunodeficiency, autosomal dominant","type":"exact"}],"termid":"MONDO:0012806","xrefs":{"Monarch":{"xref_id":"0012806"}}}


id: GO:0036267
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The growth of colonies in filamentous chains of cells into a substrate.","definition_xrefs":["GOC:di","PMID:22276126"],"direct_ancestors":[{"relation_name":"is_a","term_name":"growth of unicellular organism as a thread of attached cells","termid":"GO:0070783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"invasive filamentous growth","synonyms":[{"name":"invasive growth","type":"exact"}],"termid":"GO:0036267"}


id: GO:0015742
data:
  {"annotated_genes":["SJAG_00522","SJAG_00275"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71439],"is_not":false,"summary":null,"term":"GO:0015742"},{"annotations":[96318],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990550"}]},"cv_name":"biological_process","definition":"The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dicarboxylic acid transport","termid":"GO:0006835"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00275":null,"SJAG_00522":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"alpha-ketoglutarate transport","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"2-oxoglutarate transport","type":"exact"},{"name":"mitochondrial alpha-ketoglutarate/malate transport","type":"related"}],"termid":"GO:0015742","terms_by_termid":{"GO:0015742":null,"GO:1990550":null}}


id: PBO:0005024
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aneuploidy","termid":"PBO:0005024"}


id: PBO:0002589
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial intermediate cleavage peptidase Icp55 (predicted)","termid":"PBO:0002589"}


id: FYECO:0000248
data:
  {"alleles_by_uniquename":{"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"}},"annotation_feature_type":"gene","cv_annotations":{"fission_yeast_phenotype_condition":[{"annotations":[119086,119178],"is_not":false,"summary":null,"term":"FYECO:0000248"}]},"cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which latrunculin A was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02592":null},"genotype_count":1,"genotypes_by_uniquename":{"sty1delta":{"display_name":"sty1delta","display_uniquename":"sty1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02592:allele-1","expression":"Null"}]}]}},"is_obsolete":false,"name":"+ latA","references_by_uniquename":{"PMID:32915139":null,"PMID:33791858":null},"single_locus_annotated_genes":["SJAG_02592"],"single_locus_genotype_uniquenames":["sty1delta"],"synonyms":[{"name":"+ latrunculin A","type":"related"}],"termid":"FYECO:0000248","terms_by_termid":{"FYECO:0000248":null,"FYPO_EXT:0000001":null}}


id: GO:0009490
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete mononuclear iron electron carrier (obsolete GO:0009490)","synonyms":[{"name":"mononuclear iron electron carrier","type":"exact"}],"termid":"GO:0009490"}


id: GO:0071815
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipoprotein particle binding","termid":"GO:0071813"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"intermediate-density lipoprotein particle binding","synonyms":[{"name":"IDL binding","type":"exact"},{"name":"intermediate-density lipoprotein binding","type":"exact"}],"termid":"GO:0071815"}


id: PBO:0076399
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TAF1A antisense RNA 1","termid":"PBO:0076399"}


id: FYPO:0004263
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase, under conditions of nitrogen limitation, such as in a medium that contains a low level of NH4Cl and no other nitrogen source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal viability in stationary phase","termid":"FYPO:0001310"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0000003","FYPO:0000257"],"is_obsolete":false,"name":"normal viability in stationary phase during nitrogen limitation","synonyms":[{"name":"normal cell population viability in stationary phase during nitrogen limitation","type":"exact"}],"termid":"FYPO:0004263"}


id: GO:0070428
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","termid":"GO:0070424"},{"relation_name":"regulates","term_name":"nucleotide-binding oligomerization domain containing 1 signaling pathway","termid":"GO:0070427"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway","synonyms":[{"name":"regulation of NOD1 signaling pathway","type":"exact"},{"name":"regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway","type":"exact"}],"termid":"GO:0070428"}


id: PBO:0012604
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Triose Phosphate Isomerase","termid":"PBO:0012604"}


id: PBO:0086511
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; conserved across S. cerevisiae strains; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site","termid":"PBO:0086511"}


id: MONDO:0015803
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Botulism that is caused by toxin that is produced in a wound contaminated with Clostridium botulinum.","direct_ancestors":[{"relation_name":"is_a","term_name":"toxin-mediated infectious botulism","termid":"MONDO:0016468"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wound botulism","secondary_identifiers":["NCIT:C128342","GARD:20149","UMLS:C1306794","icd11.foundation:1674998448","ICD10CM:A48.52","SCTID:398530003","ICD9:040.42","DOID:0050353","Orphanet:178475","MEDGEN:224933"],"synonyms":[{"name":"cutaneous infectious botulism","type":"exact"},{"name":"cutaneous toxin-mediated botulism","type":"exact"},{"name":"inoculation botulism","type":"exact"},{"name":"skin infectious botulism","type":"exact"},{"name":"skin toxin-mediated botulism","type":"exact"}],"termid":"MONDO:0015803","xrefs":{"Monarch":{"xref_id":"0015803"}}}


id: PBO:0058538
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6083","termid":"PBO:0058538"}


id: PBO:0087707
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor","termid":"PBO:0087707"}


id: PBO:0088692
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"importin alpha family nuclear import signal receptor adaptor Imp1","termid":"PBO:0088692"}


id: GO:0030850
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.","definition_xrefs":["PMID:11839751"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reproductive structure development","termid":"GO:0048608"},{"relation_name":"is_a","term_name":"gland development","termid":"GO:0048732"},{"relation_name":"part_of","term_name":"urogenital system development","termid":"GO:0001655"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"prostate gland development","synonyms":[{"name":"prostate development","type":"exact"}],"termid":"GO:0030850"}


id: PBO:0003049
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ferrous iron transporter Pcl1","termid":"PBO:0003049"}


id: PBO:0056292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monoamine oxidase A","termid":"PBO:0056292"}


id: GO:0060713
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the labyrinthine layer of the placenta is generated and organized.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"embryonic morphogenesis","termid":"GO:0048598"},{"relation_name":"part_of","term_name":"embryonic placenta morphogenesis","termid":"GO:0060669"},{"relation_name":"part_of","term_name":"labyrinthine layer development","termid":"GO:0060711"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"labyrinthine layer morphogenesis","termid":"GO:0060713"}


id: GO:0032223
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synaptic transmission, cholinergic","termid":"GO:0032222"},{"relation_name":"is_a","term_name":"negative regulation of synaptic transmission","termid":"GO:0050805"},{"relation_name":"negatively_regulates","term_name":"synaptic transmission, cholinergic","termid":"GO:0007271"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of synaptic transmission, cholinergic","synonyms":[{"name":"down regulation of synaptic transmission, cholinergic","type":"exact"},{"name":"down-regulation of synaptic transmission, cholinergic","type":"exact"},{"name":"downregulation of synaptic transmission, cholinergic","type":"exact"},{"name":"inhibition of synaptic transmission, cholinergic","type":"narrow"}],"termid":"GO:0032223"}


id: GO:2000647
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell population proliferation","termid":"GO:0008285"},{"relation_name":"is_a","term_name":"regulation of stem cell proliferation","termid":"GO:0072091"},{"relation_name":"negatively_regulates","term_name":"stem cell proliferation","termid":"GO:0072089"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of stem cell proliferation","termid":"GO:2000647"}


id: PBO:0004477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted)","termid":"PBO:0004477"}


id: GO:0016411
data:
  {"annotated_genes":["SJAG_03935","SJAG_04792","SJAG_04041","SJAG_01957","SJAG_03609"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[110280],"is_not":false,"summary":null,"term":"GO:0016411"},{"annotations":[76627,89796,71443],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003841"},{"annotations":[113931],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003846"},{"annotations":[76899],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004144"}]},"cv_name":"molecular_function","definition":"Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acyltransferase activity","termid":"GO:0008374"}],"gene_count":5,"genes_by_uniquename":{"SJAG_01957":null,"SJAG_03609":null,"SJAG_03935":null,"SJAG_04041":null,"SJAG_04792":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0016746"],"is_obsolete":false,"name":"acylglycerol O-acyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-1482647","Reactome:R-HSA-1482654"],"termid":"GO:0016411","terms_by_termid":{"GO:0003841":null,"GO:0003846":null,"GO:0004144":null,"GO:0016411":null}}


id: GO:0006100
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete tricarboxylic acid cycle intermediate metabolic process (obsolete GO:0006100)","synonyms":[{"name":"Krebs cycle intermediate metabolic process","type":"exact"},{"name":"Krebs cycle intermediate metabolism","type":"exact"},{"name":"TCA intermediate metabolic process","type":"exact"},{"name":"TCA intermediate metabolism","type":"exact"},{"name":"citric acid cycle intermediate metabolic process","type":"exact"},{"name":"citric acid cycle intermediate metabolism","type":"exact"},{"name":"tricarboxylic acid cycle intermediate metabolic process","type":"exact"},{"name":"tricarboxylic acid cycle intermediate metabolism","type":"exact"}],"termid":"GO:0006100"}


id: MONDO:0003349
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive malignant smooth muscle neoplasm, arising from the central nervous system. It is characterized by a proliferation of neoplastic spindle cells.","definition_xrefs":["NCIT:C6999"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system sarcoma","termid":"MONDO:0002217"},{"relation_name":"is_a","term_name":"leiomyosarcoma","termid":"MONDO:0005058"},{"relation_name":"is_a","term_name":"malignant central nervous system mesenchymal, non-meningothelial neoplasm","termid":"MONDO:0037740"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"central nervous system leiomyosarcoma","secondary_identifiers":["DOID:5254","UMLS:C1334385","MEDGEN:235254"],"synonyms":[{"name":"CNS leiomyosarcoma","type":"exact"},{"name":"central nervous system leiomyosarcoma","type":"exact"},{"name":"leiomyosarcoma of CNS","type":"exact"},{"name":"leiomyosarcoma of central nervous system","type":"exact"},{"name":"leiomyosarcoma of the CNS","type":"exact"},{"name":"leiomyosarcoma of the central nervous system","type":"exact"}],"termid":"MONDO:0003349","xrefs":{"Monarch":{"xref_id":"0003349"}}}


id: PBO:0005497
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"major transcript in 972 h- is non functional as it contains a stop codon","termid":"PBO:0005497"}


id: SO:1000182
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A kind of chromosome variation where the chromosome complement is not an exact multiple of the haploid number.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome_variation","termid":"SO:0000240"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome_number_variation","synonyms":[{"name":"Jannovar:chromosome_number_variation","type":"exact"},{"name":"chromosome number variation","type":"exact"}],"termid":"SO:1000182"}


id: GO:0003310
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.","definition_xrefs":["GOC:dph","PMID:11076772"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enteroendocrine cell differentiation","termid":"GO:0035883"},{"relation_name":"part_of","term_name":"endocrine pancreas development","termid":"GO:0031018"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pancreatic A cell differentiation","synonyms":[{"name":"pancreatic alpha cell differentiation","type":"exact"}],"termid":"GO:0003310"}


id: PBO:0030867
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cytokinesis","termid":"PBO:0030867"}


id: GO:1903534
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of lactose biosynthetic process.","definition_xrefs":["GO_REF:0000058","GOC:mr","GOC:TermGenie","PMID:12018418"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate biosynthetic process","termid":"GO:0043255"},{"relation_name":"regulates","term_name":"lactose biosynthetic process","termid":"GO:0005989"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"regulation of lactose biosynthetic process","synonyms":[{"name":"regulation of lactose anabolism","type":"exact"},{"name":"regulation of lactose biosynthesis","type":"exact"},{"name":"regulation of lactose formation","type":"exact"},{"name":"regulation of lactose synthesis","type":"exact"}],"termid":"GO:1903534"}


id: PBO:0053050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LARP7 pseudogene 1","termid":"PBO:0053050"}


id: GO:0098959
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dendritic transport of mitochondrion","termid":"GO:0098939"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"retrograde dendritic transport of mitochondrion","synonyms":[{"name":"retrograde dendrite transport of mitochondria","type":"exact"}],"termid":"GO:0098959"}


id: PBO:0069269
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 525, pseudogene","termid":"PBO:0069269"}


id: GO:0046871
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine.","definition_xrefs":["GOC:ai","PMID:18384150"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate derivative binding","termid":"GO:0097367"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"N-acetylgalactosamine binding","synonyms":[{"name":"N-acetylgalactosamine lectin","type":"related"}],"termid":"GO:0046871"}


id: PBO:0080322
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 86 pseudogene","termid":"PBO:0080322"}


id: MONDO:0014057
data:
  {"annotated_genes":["SJAG_02433"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84896],"is_not":false,"summary":null,"term":"MONDO:0014057"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"intermediate maple syrup urine disease","termid":"MONDO:0017052"},{"relation_name":"is_a","term_name":"maple syrup urine disease","termid":"MONDO:0009563"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02433":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"maple syrup urine disease, mild variant","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:18388","UMLS:C3554575","MEDGEN:767489","OMIM:615135"],"synonyms":[{"name":"MSUDMV","type":"related"},{"name":"maple syrup urine disease, mild variant","type":"exact"}],"termid":"MONDO:0014057","terms_by_termid":{"MONDO:0014057":null},"xrefs":{"Monarch":{"xref_id":"0014057"}}}


id: PBO:0087413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated","termid":"PBO:0087413"}


id: PBO:0077993
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TraB domain containing 2A","termid":"PBO:0077993"}


id: GO:0046119
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"7-methylguanosine metabolic process","termid":"GO:0008618"},{"relation_name":"is_a","term_name":"guanosine-containing compound catabolic process","termid":"GO:1901069"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0055086","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"7-methylguanosine catabolic process","synonyms":[{"name":"7-methylguanosine breakdown","type":"exact"},{"name":"7-methylguanosine catabolism","type":"exact"},{"name":"7-methylguanosine degradation","type":"exact"}],"termid":"GO:0046119"}


id: PBO:0067872
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 174","termid":"PBO:0067872"}


id: GO:0031428
data:
  {"annotated_genes":["SJAG_02350","SJAG_00943","SJAG_00744","SJAG_02377","SJAG_03410"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[70669,73137,75288,76071,109946],"is_not":false,"summary":null,"term":"GO:0031428"}]},"cv_name":"cellular_component","definition":"A ribonucleoprotein complex containing a box C/D type RNA that is capable of ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya.","definition_xrefs":["PMID:17284456","ISBN:0879695897","PMID:11842104"],"direct_ancestors":[{"relation_name":"is_a","term_name":"box C/D RNP complex","termid":"GO:0170049"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00744":null,"SJAG_00943":null,"SJAG_02350":null,"SJAG_02377":null,"SJAG_03410":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"box C/D methylation guide snoRNP complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"box C/D sRNP complex","type":"narrow"},{"name":"box C/D small nucleolar ribonucleoprotein complex","type":"narrow"},{"name":"box C/D snoRNP complex","type":"narrow"},{"name":"box C/D snoRNP ribose 2'-O methylase complex","type":"exact"},{"name":"box C/D snoRNP ribose-2'-O-methyltransferase complex","type":"narrow"}],"termid":"GO:0031428","terms_by_termid":{"GO:0031428":null}}


id: MONDO:1012878
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any cerebellar ataxia that occurs in dogs due to a mutation in the SELENOP gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebellar ataxia, dog","termid":"MONDO:1012957"},{"relation_name":"is_a","term_name":"hereditary cerebellar ataxia, non-human animal","termid":"MONDO:1012960"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebellar ataxia, SELENOP-related, dog","secondary_identifiers":["OMIA:002367-9615"],"synonyms":[{"name":"CACA","type":"exact"},{"name":"CNS atrophy with cerebellar ataxia","type":"related"},{"name":"ataxia, cerebellar, SELENOP-related, dog","type":"exact"}],"termid":"MONDO:1012878","xrefs":{"Monarch":{"xref_id":"1012878"}}}


id: PBO:0039299
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ALG13 UDP-N-acetylglucosaminyltransferase subunit","termid":"PBO:0039299"}


id: PBO:0113012
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Atypical protein kinase; along with paralog, ALK2, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of formins and polarisome components in mitosis, and survival after spindle assembly checkpoint delay; regulates the morphogenesis checkpoint in response to polarity insults through inactivation of Mih1p; phosphorylated in response to DNA damage; similar to mammalian haspins","termid":"PBO:0113012"}


id: MONDO:0004936
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A complication of obstetric labor in which the corpus of the uterus is forced completely or partially through the uterine cervix. This can occur during the late stages of labor and is associated with immediate postpartum hemorrhage.","definition_xrefs":["MESH:D019687"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uterine disorder","termid":"MONDO:0002654"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uterine inversion","secondary_identifiers":["SCTID:27215002","UMLS:C0162482","DOID:997","MEDGEN:57916","ICD9:665.2"],"termid":"MONDO:0004936","xrefs":{"Monarch":{"xref_id":"0004936"}}}


id: PBO:0088143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar serine-type carboxypeptidase; involved, along with functional homolog Prc1p, in vacuolar zymogen activation, breakdown of the autophagic body, and autophagosome-dependent protein synthesis; role in phytochelatin synthesis; localizes to the vacuole lumen; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner; N-glycosylated","termid":"PBO:0088143"}


id: PBO:0083143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps 5' end of ORF YMR317W","termid":"PBO:0083143"}


id: PBO:0046499
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ERH pseudogene 2","termid":"PBO:0046499"}


id: PBO:0030403
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_potassium_chloride","termid":"PBO:0030403"}


id: SO:0002252
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"CDS region corresponding to a transit peptide region of a polypeptide.","direct_ancestors":[{"relation_name":"is_a","term_name":"CDS_region","termid":"SO:0000851"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transit_peptide_region_of_CDS","synonyms":[{"name":"INSDC_feature:transit_peptide","type":"exact"},{"name":"transit peptide region of CDS","type":"exact"}],"termid":"SO:0002252"}


id: PBO:0051714
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"INSIG1 divergent transcript","termid":"PBO:0051714"}


id: PBO:0066959
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 261","termid":"PBO:0066959"}


id: PBO:0045890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 gamma pseudogene 2","termid":"PBO:0045890"}


id: GO:0014015
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.","definition_xrefs":["GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of gliogenesis","termid":"GO:0014013"},{"relation_name":"is_a","term_name":"positive regulation of neurogenesis","termid":"GO:0050769"},{"relation_name":"positively_regulates","term_name":"gliogenesis","termid":"GO:0042063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of gliogenesis","synonyms":[{"name":"activation of gliogenesis","type":"narrow"},{"name":"stimulation of gliogenesis","type":"narrow"},{"name":"up regulation of gliogenesis","type":"exact"},{"name":"up-regulation of gliogenesis","type":"exact"},{"name":"upregulation of gliogenesis","type":"exact"}],"termid":"GO:0014015"}


id: PATO:0001978
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape quality inhering in a bearer by virtue of the bearer's being regularly divided by deep incisions.","definition_xrefs":["ISBN:0881923214"],"direct_ancestors":[{"relation_name":"is_a","term_name":"shape","termid":"PATO:0000052"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cut","synonyms":[{"name":"incised","type":"exact"}],"termid":"PATO:0001978"}


id: MONDO:0014081
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Severe combined immunodeficiency due to CARD11 deficiency is a rare combined T and B cell immunodeficiency characterized by normal numbers of T and B lymphocytes, increased numbers of transitional B cells and hypo- to agammaglobulinemia, decreased numbers of regulatory T cells and defects in T-cell functions. It presents with severe susceptibility to infections, including opportunistic infections.","definition_xrefs":["Orphanet:357237"],"direct_ancestors":[{"relation_name":"is_a","term_name":"T+ B+ severe combined immunodeficiency","termid":"MONDO:0044201"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"severe combined immunodeficiency due to CARD11 deficiency","secondary_identifiers":["OMIM:615206","DOID:0111957","UMLS:C3554686","GARD:17549","MEDGEN:767600"],"synonyms":[{"name":"CARD11 immunodeficiency","type":"related"},{"name":"IMD11","type":"related"},{"name":"IMD11A","type":"related"},{"name":"SCID due to CARD11 deficiency","type":"exact"},{"name":"immunodeficiency 11","type":"related"},{"name":"immunodeficiency 11A","type":"exact"},{"name":"immunodeficiency type 11","type":"exact"}],"termid":"MONDO:0014081","xrefs":{"Monarch":{"xref_id":"0014081"}}}


id: PBO:0042832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cholesteryl ester transfer protein","termid":"PBO:0042832"}


id: PBO:0001693
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monothiol glutaredoxin Grx5","termid":"PBO:0001693"}


id: PBO:0018193
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamate-cysteine ligase regulatory subunit Gcs2 (predicted)","termid":"PBO:0018193"}


id: PBO:0082659
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the CCR4-NOT transcriptional complex; CCR4-NOT is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening","termid":"PBO:0082659"}


id: PR:O42649
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A structural maintenance of chromosomes protein 3 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR18937:SF8","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"structural maintenance of chromosomes protein 3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC10F6.09c","secondary_identifiers":["UniProtKB:O42649"],"synonyms":[{"name":"SPAC10F6.09c","type":"related"},{"name":"Spom972h-SMC3","type":"exact"},{"name":"cohesin complex Psm3 subunit (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"smc3","type":"related"}],"termid":"PR:O42649"}


id: SOFP:synonym
data:
  {"annotation_feature_type":"gene","cv_name":"feature_property","definition":"Historic community symbol, may have originally been symbol","direct_ancestors":[{"relation_name":"is_a","term_name":"feature_property","termid":"SOFP:feature_property"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synonym","termid":"SOFP:synonym"}


id: GO:0016727
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on CH or CH2 groups","termid":"GO:0016725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor","secondary_identifiers":["EC:1.17.3.-"],"termid":"GO:0016727"}


id: PBO:0053629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 674","termid":"PBO:0053629"}


id: GO:0090248
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.","definition_xrefs":["GOC:tb","GOC:dph","GOC:ascb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell migration","termid":"GO:0016477"},{"relation_name":"part_of","term_name":"axis elongation involved in somitogenesis","termid":"GO:0090245"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell migration involved in somitogenic axis elongation","secondary_identifiers":["GO:0090247"],"synonyms":[{"name":"cell motility involved in somitogenic axis elongation","type":"broad"}],"termid":"GO:0090248"}


id: GO:0003412
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye.","definition_xrefs":["GOC:ascb_2009","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of epithelial cell apical/basal polarity","termid":"GO:0045198"},{"relation_name":"part_of","term_name":"camera-type eye morphogenesis","termid":"GO:0048593"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007163"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007163"],"is_obsolete":false,"name":"establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis","termid":"GO:0003412"}


id: GO:0098834
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The cytoplasmic component of the presynaptic endocytic zone.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cortex region","termid":"GO:0099738"},{"relation_name":"part_of","term_name":"presynaptic endocytic zone","termid":"GO:0098833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0005938"},{"rel_name":"is_a","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0005938"],"is_obsolete":false,"name":"presynaptic endocytic zone cytoplasmic component","synonyms":[{"name":"cortex of presynaptic endocytic zone","type":"exact"}],"termid":"GO:0098834"}


id: GO:0106059
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA.","definition_xrefs":["RHEA:42968"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA (cytidine) methyltransferase activity","termid":"GO:0016427"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140101"}],"interesting_parent_ids":["GO:0003674","GO:0016741","GO:0140101","GO:0140098","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"tRNA (cytidine(56)-2'-O)-methyltransferase activity","secondary_identifiers":["EC:2.1.1.206","MetaCyc:RXN-11869"],"synonyms":[{"name":"tRNA (cytidine 56-2'-O)-methyltransferase activity","type":"exact"}],"termid":"GO:0106059"}


id: PBO:0113001
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha subunit of translation initiation factor eIF2B (eIF2Bα); guanine-nucleotide exchange factor for eIF2; mutations in eIF2Bα alter localization of eIF2B; activity regulated by phosphorylated eIF2; positive regulator of GCN4 expression; mutations in human ortholog EIF2B2 cause fatal brain disease childhood ataxia with central nervous system hypomyelination (CACH); human ortholog EIF2B1 can complement yeast null mutant","termid":"PBO:0113001"}


id: MONDO:0018158
data:
  {"annotated_genes":["SJAG_03813","SJAG_02658","SJAG_04183","SJAG_02656","SJAG_01649","SJAG_03332","SJAG_00404","SJAG_01179","SJAG_00885","SJAG_03773","SJAG_00522","SJAG_01524","SJAG_02050","SJAG_00634"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84903],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014062"},{"annotations":[85132],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011283"},{"annotations":[86959],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014959"},{"annotations":[85687],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014175"},{"annotations":[85602],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014820"},{"annotations":[86946],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014943"},{"annotations":[86765,86764],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032815"},{"annotations":[85271],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032932"},{"annotations":[86821],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008758"},{"annotations":[86823],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013350"},{"annotations":[85411],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009747"},{"annotations":[86093],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012792"},{"annotations":[86989],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009504"},{"annotations":[86092],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012791"},{"annotations":[85460],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008922"},{"annotations":[86439],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013776"}]},"cv_name":"mondo","definition":"The mitochondrial DNA (mtDNA) depletion syndrome (MDS) is a clinically heterogeneous group of mitochondrial disorders characterized by a reduction of the mtDNA copy number in affected tissues without mutations or rearrangements in the mtDNA. MDS is phenotypically heterogeneous, and can affect a specific organ or a combination of organs, with the main presentations described being either hepatocerebral (i.e. hepatic dysfunction, psychomotor delay), myopathic (i.e. hypotonia, muscle weakness, bulbar weakness), encephalomyopathic (i.e. hypotonia, muscle weakness, psychomotor delay) or neurogastrointestinal (i.e gastrointestinal dysmotility, peripheral neuropathy). Additional phenotypes include fatal infantile lactic acidosis with methylmalonic aciduria, spastic ataxia (early-onset spastic ataxia-neuropathy syndrome), and Alpers syndrome.","definition_xrefs":["Orphanet:35698"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete metabolic disorder with intestinal involvement (obsolete MONDO:0015188)","termid":"MONDO:0015188"},{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00404":null,"SJAG_00522":null,"SJAG_00634":null,"SJAG_00885":null,"SJAG_01179":null,"SJAG_01524":null,"SJAG_01649":null,"SJAG_02050":null,"SJAG_02656":null,"SJAG_02658":null,"SJAG_03332":null,"SJAG_03773":null,"SJAG_03813":null,"SJAG_04183":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial DNA depletion syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1159345506","OMIMPS:603041","GARD:13643","MedDRA:10059396","NANDO:2200523","NANDO:2200528","DOID:0070329","MEDGEN:452449","UMLS:C0342782"],"synonyms":[{"name":"mtDNA depletion syndrome","type":"exact"}],"termid":"MONDO:0018158","terms_by_termid":{"MONDO:0008758":null,"MONDO:0008922":null,"MONDO:0009504":null,"MONDO:0009747":null,"MONDO:0011283":null,"MONDO:0012791":null,"MONDO:0012792":null,"MONDO:0013350":null,"MONDO:0013776":null,"MONDO:0014062":null,"MONDO:0014175":null,"MONDO:0014820":null,"MONDO:0014943":null,"MONDO:0014959":null,"MONDO:0032815":null,"MONDO:0032932":null},"xrefs":{"Monarch":{"xref_id":"0018158"}}}


id: PBO:0065697
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pumilio RNA binding family member 2","termid":"PBO:0065697"}


id: GO:0044079
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont alters or subverts the regulated release of a neurotransmitter from a cell in its host organism.","definition_xrefs":["MITRE:tk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host cellular process","termid":"GO:0044068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host neurotransmitter secretion","synonyms":[{"name":"modification by symbiont of host neurotransmitter secretion","type":"exact"},{"name":"modulation by symbiont of host neurotransmitter secretion","type":"exact"},{"name":"modulation of host neurotransmitter secretion by symbiont","type":"exact"},{"name":"regulation by symbiont of host neurotransmitter secretion","type":"exact"}],"termid":"GO:0044079"}


id: PBO:0001806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fungal cellulose binding domain protein","termid":"PBO:0001806"}


id: FYPO:0003528
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the actomyosin contractile ring is observed there.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mislocalized protein during vegetative growth","termid":"FYPO:0000782"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"protein mislocalized to actomyosin contractile ring","synonyms":[{"name":"ectopic protein localization to actomyosin contractile ring","type":"exact"},{"name":"protein mislocalised to actomyosin contractile ring","type":"exact"},{"name":"protein mislocalised to actomyosin contractile ring during vegetative growth","type":"exact"},{"name":"protein mislocalized to actomyosin contractile ring during mitotic cell cycle","type":"related"},{"name":"protein mislocalized to actomyosin contractile ring during vegetative growth","type":"exact"},{"name":"protein mislocalized to cytokinetic contractile ring","type":"exact"},{"name":"protein mislocalized to mitotic contractile ring","type":"exact"}],"termid":"FYPO:0003528"}


id: PBO:0034407
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-transcriptionally_regulates_(obsolete_transcriptionally_regulates)","termid":"PBO:0034407"}


id: MONDO:0011005
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trisomy 18-like syndrome","secondary_identifiers":["MESH:C563382","MEDGEN:331340","OMIM:601161","UMLS:C1832677"],"synonyms":[{"name":"trisomy 18-like syndrome","type":"exact"}],"termid":"MONDO:0011005","xrefs":{"Monarch":{"xref_id":"0011005"}}}


id: PBO:0080884
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"yrdC N6-threonylcarbamoyltransferase domain containing","termid":"PBO:0080884"}


id: MONDO:0001236
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign or malignant neoplasm involving the appendix.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cecal neoplasm","termid":"MONDO:0005694"},{"relation_name":"is_a","term_name":"disorder of appendix","termid":"MONDO:0056798"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"appendiceal neoplasm","secondary_identifiers":["MEDGEN:1629","EFO:0003880","DOID:11240","MESH:D001063","NCIT:C4434","UMLS:C0003614","SCTID:126846004"],"synonyms":[{"name":"appendix neoplasm","type":"exact"},{"name":"appendix tumor","type":"exact"},{"name":"appendix tumour","type":"exact"},{"name":"neoplasm of appendix","type":"exact"},{"name":"neoplasm of the appendix","type":"exact"},{"name":"neoplasm of vermiform appendix","type":"exact"},{"name":"tumor of appendix","type":"exact"},{"name":"tumor of the appendix","type":"exact"},{"name":"tumor of vermiform appendix","type":"exact"},{"name":"tumour of appendix","type":"exact"},{"name":"tumour of the appendix","type":"exact"},{"name":"tumour of vermiform appendix","type":"exact"},{"name":"vermiform appendix neoplasm","type":"exact"},{"name":"vermiform appendix neoplasm (disease)","type":"exact"},{"name":"vermiform appendix tumor","type":"exact"},{"name":"vermiform appendix tumour","type":"exact"}],"termid":"MONDO:0001236","xrefs":{"Monarch":{"xref_id":"0001236"}}}


id: PBO:0088177
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Zeta subunit of the coatomer complex (COPI); COPI coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER","termid":"PBO:0088177"}


id: PBO:0113223
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Multicopper oxidase; integral membrane protein with similarity to Fet3p; targeted to vacuole via AP-3 pathway; may have role in iron transport","termid":"PBO:0113223"}


id: PBO:0062176
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily M member 1","termid":"PBO:0062176"}


id: MONDO:1012716
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any difference of sexual development that occurs in horses with a XY karyotype.","definition_xrefs":["OMIA:001601-9796"],"direct_ancestors":[{"relation_name":"is_a","term_name":"difference of sexual differentiation, non-human animal","termid":"MONDO:0700105"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"XY difference of sexual development, horse","termid":"MONDO:1012716","xrefs":{"Monarch":{"xref_id":"1012716"}}}


id: PBO:0028008
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_during_meiotic_cell_cycle","termid":"PBO:0028008"}


id: PBO:0085600
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in cell separation during budding; one of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; may play an indirect role in fluid-phase endocytosis; protein abundance increases in response to DNA replication stress; SDS24 has a paralog, SDS23, that arose from the whole genome duplication","termid":"PBO:0085600"}


id: PBO:0080751
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-box binding protein 1 pseudogene 1","termid":"PBO:0080751"}


id: GO:0102629
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: patuletin + S-adenosyl-L-methionine = quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete patuletin 3'-O-methyltransferase activity (obsolete GO:0102629)","termid":"GO:0102629"}


id: PBO:0031065
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_after_spore_germination_with_normal,_septated_germ_tube_morphology","termid":"PBO:0031065"}


id: MONDO:0015274
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chronic beryllium disease (CBD) is a granulomatous, interstitial lung disease that occurs in individuals who develop beryllium sensitization (BeS), a cell-mediated immune response to environmental and occupational beryllium exposure. BeS precedes the lung disease that may present with chronic dry cough, fatigue, weight loss, chest pain, and increasing dyspnea.","definition_xrefs":["Orphanet:133"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pneumoconiosis","termid":"MONDO:0015926"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic beryllium disease","secondary_identifiers":["EFO:0007168","GARD:867","MEDGEN:67440","MESH:D001607","SCTID:18121009","UMLS:C0221052","DOID:10322","MedDRA:10004485","icd11.foundation:212013370","ICD9:503"],"synonyms":[{"name":"Beryllliosis","type":"related"},{"name":"Subacute berylliosis","type":"related"},{"name":"acute berylliosis","type":"related"},{"name":"berylliosis","type":"exact"},{"name":"beryllium disease","type":"related"},{"name":"beryllium poisoning","type":"exact"},{"name":"chronic berylliosis","type":"exact"},{"name":"chronic beryllium lung disease","type":"exact"},{"name":"chronic pulmonary berylliosis","type":"related"},{"name":"reversible berylliosis","type":"related"}],"termid":"MONDO:0015274","xrefs":{"Monarch":{"xref_id":"0015274"}}}


id: PBO:0054400
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1796","termid":"PBO:0054400"}


id: GO:0043558
data:
  {"annotated_genes":["SJAG_00169","SJAG_00786","SJAG_02592","SJAG_03869","SJAG_04873","SJAG_02072","SJAG_00690","SJAG_04383","SJAG_01942"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94127,74995,69717,99096,109422,115358],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990625"},{"annotations":[103716,94982,103081],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990611"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of translational initiation","termid":"GO:0006446"},{"relation_name":"is_a","term_name":"regulation of translation in response to stress","termid":"GO:0043555"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00169":null,"SJAG_00690":null,"SJAG_00786":null,"SJAG_01942":null,"SJAG_02072":null,"SJAG_02592":null,"SJAG_03869":null,"SJAG_04383":null,"SJAG_04873":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of translational initiation in response to stress","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"regulation of translation initiation in response to stress","type":"exact"}],"termid":"GO:0043558","terms_by_termid":{"GO:1990611":null,"GO:1990625":null}}


id: PBO:0016051
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"not functionally complemented by human cofactor E","termid":"PBO:0016051"}


id: MONDO:0958115
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"combined immunodeficiency","termid":"MONDO:0015131"},{"relation_name":"is_a","term_name":"hyper-IgE syndrome","termid":"MONDO:0018037"},{"relation_name":"is_a","term_name":"bent bone dysplasia","termid":"MONDO:0019698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"autosomal recessive combined immunodeficiency due to complete IL6ST deficiency","secondary_identifiers":["MEDGEN:1864006","Orphanet:656283","UMLS:C5925103"],"termid":"MONDO:0958115","xrefs":{"Monarch":{"xref_id":"0958115"}}}


id: MONDO:0006473
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete tracheal squamous cell carcinoma (obsolete MONDO:0006473)","termid":"MONDO:0006473","xrefs":{"Monarch":{"xref_id":"0006473"}}}


id: MONDO:0012232
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"stutter disorder","termid":"MONDO:0000723"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stuttering, familial persistent, 2","secondary_identifiers":["MESH:C563756","UMLS:C1836484","OMIM:609261","MEDGEN:332218"],"synonyms":[{"name":"STUT2","type":"exact"},{"name":"stuttering, familial persistent, 2","type":"exact"}],"termid":"MONDO:0012232","xrefs":{"Monarch":{"xref_id":"0012232"}}}


id: MONDO:0002568
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Narrowing of the lumen of the trachea.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tracheal disorder","termid":"MONDO:0002567"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tracheal stenosis","secondary_identifiers":["SCTID:11296007","NANDO:2200194","UMLS:C0040583","MESH:D014135","NCIT:C78646","DOID:3227","ICD9:519.19","MEDGEN:21227"],"synonyms":[{"name":"stenosis of trachea","type":"exact"}],"termid":"MONDO:0002568","xrefs":{"Monarch":{"xref_id":"0002568"}}}


id: MONDO:0015831
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mullerian aplasia","termid":"MONDO:0019128"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unilateral aplasia of the mullerian ducts","secondary_identifiers":["Orphanet:180071","UMLS:C0266389","GARD:20173","MEDGEN:78600"],"synonyms":[{"name":"unicornuate uterus","type":"exact"},{"name":"unilateral aplasia of the Müllerian ducts","type":"related"}],"termid":"MONDO:0015831","xrefs":{"Monarch":{"xref_id":"0015831"}}}


id: PBO:0077219
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation machinery associated 16 homolog pseudogene 2","termid":"PBO:0077219"}


id: PBO:0054385
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1781","termid":"PBO:0054385"}


id: PBO:0066547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of G protein signaling 10","termid":"PBO:0066547"}


id: GO:1990627
data:
  {"annotated_genes":["SJAG_02656"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104666],"is_not":false,"summary":null,"term":"GO:1990627"}]},"cv_name":"biological_process","definition":"The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.","definition_xrefs":["GOC:vw","PMID:17055438"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inner mitochondrial membrane organization","termid":"GO:0007007"},{"relation_name":"part_of","term_name":"mitochondrial fusion","termid":"GO:0008053"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02656":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007005"},{"rel_name":"part_of","termid":"GO:0007005"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0007005","GO:0008150","GO:0061024"],"is_obsolete":false,"name":"mitochondrial inner membrane fusion","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"mitochondrion inner membrane fusion","type":"exact"}],"termid":"GO:1990627","terms_by_termid":{"GO:1990627":null}}


id: PBO:0091839
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"do not confuse with Sty1","termid":"PBO:0091839"}


id: MONDO:0019428
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare X-linked syndrome characterized by psychomotor delay, intellectual deficit, hydrocephalus, and mild facial anomalies.","definition_xrefs":["Orphanet:85335"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fried syndrome","secondary_identifiers":["UMLS:C4305134","GARD:16753","SCTID:718848000","MEDGEN:930803"],"termid":"MONDO:0019428","xrefs":{"Monarch":{"xref_id":"0019428"}}}


id: GO:0019263
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adamantanone metabolic process","termid":"GO:0018866"},{"relation_name":"is_a","term_name":"xenobiotic catabolic process","termid":"GO:0042178"},{"relation_name":"is_a","term_name":"ketone catabolic process","termid":"GO:0042182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"adamantanone catabolic process","secondary_identifiers":["MetaCyc:P481-PWY"],"synonyms":[{"name":"adamantanone breakdown","type":"exact"},{"name":"adamantanone catabolism","type":"exact"},{"name":"adamantanone degradation","type":"exact"}],"termid":"GO:0019263"}


id: FYPO:0008018
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glutamine as the nitrogen source.","definition_xrefs":["PMID:7903653","PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002060"}],"interesting_parent_ids":["FYPO:0002060","FYPO:0000139","FYPO:0000257","FYPO:0002058","FYPO:0000003","FYPO:0002057"],"is_obsolete":false,"name":"normal growth on glutamine nitrogen source","synonyms":[{"name":"normal cell population growth on glutamine nitrogen source","type":"exact"}],"termid":"FYPO:0008018"}


id: GO:0009989
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Cell recognition that involves the interaction of the cell with the extracellular matrix.","definition_xrefs":["ISBN:0824072820"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell recognition","termid":"GO:0008037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell-matrix recognition","termid":"GO:0009989"}


id: PBO:0045406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DPPA3 pseudogene 8","termid":"PBO:0045406"}


id: PBO:0064024
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 58","termid":"PBO:0064024"}


id: GO:0060758
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"foraging behavior","termid":"GO:0060756"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"foraging behavior by probing substrate","termid":"GO:0060758"}


id: GO:1901258
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.","definition_xrefs":["GOC:TermGenie","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cytokine production","termid":"GO:0001819"},{"relation_name":"is_a","term_name":"regulation of macrophage colony-stimulating factor production","termid":"GO:1901256"},{"relation_name":"positively_regulates","term_name":"macrophage colony-stimulating factor production","termid":"GO:0036301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of macrophage colony-stimulating factor production","synonyms":[{"name":"activation of M-CSF production","type":"exact"},{"name":"activation of macrophage colony-stimulating factor production","type":"narrow"},{"name":"positive regulation of M-CSF production","type":"exact"},{"name":"up regulation of M-CSF production","type":"exact"},{"name":"up regulation of macrophage colony-stimulating factor production","type":"exact"},{"name":"up-regulation of M-CSF production","type":"exact"},{"name":"up-regulation of macrophage colony-stimulating factor production","type":"exact"},{"name":"upregulation of M-CSF production","type":"exact"},{"name":"upregulation of macrophage colony-stimulating factor production","type":"exact"}],"termid":"GO:1901258"}


id: PBO:0075755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sushi repeat containing protein X-linked 2","termid":"PBO:0075755"}


id: PBO:0057098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 193b","termid":"PBO:0057098"}


id: GO:0004817
data:
  {"annotated_genes":["SJAG_00420"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[72233],"is_not":false,"summary":null,"term":"GO:0004817"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).","definition_xrefs":["EC:6.1.1.16"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoacyl-tRNA ligase activity","termid":"GO:0004812"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00420":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140098"}],"interesting_parent_ids":["GO:0140101","GO:0003674","GO:0140098","GO:0003824","GO:0016874"],"is_obsolete":false,"name":"cysteine-tRNA ligase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-380158","MetaCyc:CYSTEINE--TRNA-LIGASE-RXN","RHEA:17773","Reactome:R-HSA-379887"],"synonyms":[{"name":"L-cysteine:tRNACys ligase (AMP-forming)","type":"related"},{"name":"cysteine translase activity","type":"related"},{"name":"cysteinyl-tRNA synthetase activity","type":"exact"},{"name":"cysteinyl-transfer ribonucleate synthetase activity","type":"related"},{"name":"cysteinyl-transferRNA synthetase activity","type":"related"}],"termid":"GO:0004817","terms_by_termid":{"GO:0004817":null}}


id: PBO:0074118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 30 member 4","termid":"PBO:0074118"}


id: PBO:0047665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fukutin related protein","termid":"PBO:0047665"}


id: GO:1903935
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.","definition_xrefs":["GOC:TermGenie","PMID:18674524","GO_REF:0000071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to arsenic-containing substance","termid":"GO:0046685"},{"relation_name":"is_a","term_name":"response to salt","termid":"GO:1902074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to sodium arsenite","termid":"GO:1903935"}


id: PBO:0072112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S14 pseudogene 1","termid":"PBO:0072112"}


id: GO:0050532
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H2O = (R)-3-sulfolactate + phosphate.","definition_xrefs":["EC:3.1.3.71","RHEA:23416"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatase activity","termid":"GO:0016791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0003674","GO:0016788","GO:0016787","GO:0003824"],"is_obsolete":false,"name":"2-phosphosulfolactate phosphatase activity","secondary_identifiers":["KEGG_REACTION:R05789","MetaCyc:R229-RXN"],"synonyms":[{"name":"(2R)-phosphosulfolactate phosphohydrolase activity","type":"related"},{"name":"(R)-2-phospho-3-sulfolactate phosphohydrolase activity","type":"related"},{"name":"2-phosphosulpholactate phosphatase activity","type":"exact"},{"name":"ComB phosphatase activity","type":"related"}],"termid":"GO:0050532"}


id: PBO:0051166
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 3-49","termid":"PBO:0051166"}


id: MONDO:0019921
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Paternal uniparental disomy of chromosome 6 is an uniparental disomy of paternal origin characterized by intrauterine growth retardation, transient neonatal diabetes mellitus, and macroglossia.","definition_xrefs":["Orphanet:96191"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome 6 disorder","termid":"MONDO:0700013"},{"relation_name":"is_a","term_name":"uniparental disomy","termid":"MONDO:0700086"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paternal uniparental disomy of chromosome 6","secondary_identifiers":["GARD:19340","icd11.foundation:1267556610","MEDGEN:1662050","UMLS:C4749378"],"synonyms":[{"name":"UPD(6)pat","type":"exact"},{"name":"paternal uniparental disomy of chromosome type 6","type":"exact"}],"termid":"MONDO:0019921","xrefs":{"Monarch":{"xref_id":"0019921"}}}


id: MONDO:0013652
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any narcolepsy in which the cause of the disease is a mutation in the MOG gene.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"narcolepsy-cataplexy syndrome","termid":"MONDO:0016158"},{"relation_name":"is_a","term_name":"hereditary narcolepsy","termid":"MONDO:0100554"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"narcolepsy 7","secondary_identifiers":["UMLS:C3280266","MEDGEN:481896","OMIM:614250","GARD:15783"],"synonyms":[{"name":"MOG narcolepsy","type":"exact"},{"name":"NRCLP7","type":"related"},{"name":"narcolepsy 7","type":"exact"},{"name":"narcolepsy caused by mutation in MOG","type":"exact"},{"name":"narcolepsy type 7","type":"exact"}],"termid":"MONDO:0013652","xrefs":{"Monarch":{"xref_id":"0013652"}}}


id: MONDO:0006234
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"High grade prostatic intraepithelial neoplasia characterized by the presence of severe architectural and cytologic abnormalities.","definition_xrefs":["NCIT:C3642"],"direct_ancestors":[{"relation_name":"is_a","term_name":"in situ carcinoma","termid":"MONDO:0004647"},{"relation_name":"is_a","term_name":"prostate carcinoma","termid":"MONDO:0005159"},{"relation_name":"is_a","term_name":"prostate intraepithelial neoplasia","termid":"MONDO:0005193"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"grade III prostatic intraepithelial neoplasia","secondary_identifiers":["DOID:8634","EFO:1000283","ICD9:233.4","SCTID:92691004","UMLS:C5200982","MEDGEN:1684800","ICD10CM:D07.5"],"synonyms":[{"name":"PIN III","type":"exact"},{"name":"adenocarcinoma in situ of prostate","type":"exact"},{"name":"adenocarcinoma in situ of the prostate","type":"exact"},{"name":"carcinoma in situ of prostate","type":"exact"},{"name":"carcinoma in situ of prostate gland","type":"exact"},{"name":"grade 3 pin","type":"exact"},{"name":"grade 3 prostatic intraepithelial neoplasia","type":"exact"},{"name":"grade III pin","type":"exact"},{"name":"pin III","type":"exact"},{"name":"prostate adenocarcinoma in situ","type":"exact"},{"name":"prostate carcinoma in situ","type":"exact"},{"name":"prostate gland carcinoma in situ","type":"exact"},{"name":"prostate gland in situ carcinoma","type":"exact"},{"name":"stage 0 prostate gland carcinoma","type":"exact"}],"termid":"MONDO:0006234","xrefs":{"Monarch":{"xref_id":"0006234"}}}


id: PBO:0029916
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_ergosterol_level","termid":"PBO:0029916"}


id: GO:0042187
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"p-xylene metabolic process","termid":"GO:0018951"},{"relation_name":"is_a","term_name":"xylene catabolic process","termid":"GO:0042184"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"p-xylene catabolic process","synonyms":[{"name":"p-xylene breakdown","type":"exact"},{"name":"p-xylene catabolism","type":"exact"},{"name":"p-xylene degradation","type":"exact"},{"name":"para-xylene catabolic process","type":"exact"},{"name":"para-xylene catabolism","type":"exact"}],"termid":"GO:0042187"}


id: GO:0102646
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol = all-trans-geranylfarnesol + H2O.","definition_xrefs":["PMID:24200803","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"14betaH-scalarane-17alpha-19-diol synthase activity","secondary_identifiers":["MetaCyc:RXN-15759"],"termid":"GO:0102646"}


id: GO:0000207
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).","definition_xrefs":["PMID:9561267"],"gene_count":0,"genotype_count":0,"name":"obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces) (obsolete GO:0000207)","synonyms":[{"name":"nuclear translocation of MAPK during sporulation (sensu Saccharomyces)","type":"exact"}],"termid":"GO:0000207"}


id: GO:0032574
data:
  {"annotated_genes":["SJAG_02242"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[99647],"is_not":false,"summary":null,"term":"GO:0032574"}]},"cv_name":"molecular_function","definition":"Unwinding of an RNA helix in the 5' to 3' direction, driven by ATP hydrolysis.","definition_xrefs":["GOC:jp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA helicase activity","termid":"GO:0003724"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02242":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016853","GO:0140098","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"5'-3' RNA helicase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0032575","Reactome:R-HSA-9694265","EC:5.6.2.5","Reactome:R-HSA-9682695"],"synonyms":[{"name":"5' to 3' RNA helicase activity","type":"exact"},{"name":"ATP-dependent 5' to 3' RNA helicase activity","type":"exact"},{"name":"ATP-dependent 5'-3' RNA helicase activity","type":"exact"}],"termid":"GO:0032574","terms_by_termid":{"GO:0032574":null}}


id: GO:1900672
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of F-9775A biosynthetic process","termid":"GO:1900670"},{"relation_name":"is_a","term_name":"positive regulation of polyketide biosynthetic process","termid":"GO:1900734"},{"relation_name":"positively_regulates","term_name":"F-9775A biosynthetic process","termid":"GO:1900611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"positive regulation of F-9775A biosynthetic process","synonyms":[{"name":"activation of F-9775A anabolism","type":"exact"},{"name":"activation of F-9775A biosynthesis","type":"exact"},{"name":"activation of F-9775A biosynthetic process","type":"narrow"},{"name":"activation of F-9775A formation","type":"exact"},{"name":"activation of F-9775A synthesis","type":"exact"},{"name":"positive regulation of F-9775A anabolism","type":"exact"},{"name":"positive regulation of F-9775A biosynthesis","type":"exact"},{"name":"positive regulation of F-9775A formation","type":"exact"},{"name":"positive regulation of F-9775A synthesis","type":"exact"},{"name":"up regulation of F-9775A anabolism","type":"exact"},{"name":"up regulation of F-9775A biosynthesis","type":"exact"},{"name":"up regulation of F-9775A biosynthetic process","type":"exact"},{"name":"up regulation of F-9775A formation","type":"exact"},{"name":"up regulation of F-9775A synthesis","type":"exact"},{"name":"up-regulation of F-9775A anabolism","type":"exact"},{"name":"up-regulation of F-9775A biosynthesis","type":"exact"},{"name":"up-regulation of F-9775A biosynthetic process","type":"exact"},{"name":"up-regulation of F-9775A formation","type":"exact"},{"name":"up-regulation of F-9775A synthesis","type":"exact"},{"name":"upregulation of F-9775A anabolism","type":"exact"},{"name":"upregulation of F-9775A biosynthesis","type":"exact"},{"name":"upregulation of F-9775A biosynthetic process","type":"exact"},{"name":"upregulation of F-9775A formation","type":"exact"},{"name":"upregulation of F-9775A synthesis","type":"exact"}],"termid":"GO:1900672"}


id: GO:0048794
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.","definition_xrefs":["GOC:mh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"animal organ development","termid":"GO:0048513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"swim bladder development","synonyms":[{"name":"gas bladder development","type":"exact"}],"termid":"GO:0048794"}


id: PBO:0091170
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit L35","termid":"PBO:0091170"}


id: PBO:0055804
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysophosphatidic acid receptor 6","termid":"PBO:0055804"}


id: MONDO:0004647
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant epithelial neoplasm which is confined to the epithelial layer without evidence of further tissue invasion.","definition_xrefs":["NCIT:C2917"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"pre-malignant neoplasm","termid":"MONDO:0000611"},{"relation_name":"is_a","term_name":"carcinoma","termid":"MONDO:0004993"},{"relation_name":"is_a","term_name":"high grade malignant neoplasm","termid":"MONDO:0020665"},{"relation_name":"is_a","term_name":"precancerous condition","termid":"MONDO:0021074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"in situ carcinoma","secondary_identifiers":["ICD9:234.9","MESH:D002278","ICD9:234.8","MEDGEN:763","UMLS:C0007099","SCTID:109355002","DOID:8719","ICD9:230-234.99","ICDO:8010/2"],"synonyms":[{"name":"CIS","type":"broad"},{"name":"carcinoma in situ","type":"exact"},{"name":"carcinoma, in situ, malignant","type":"exact"},{"name":"epithelial tumor, in situ, malignant","type":"exact"},{"name":"intraepithelial carcinoma","type":"exact"},{"name":"non-invasive carcinoma","type":"exact"},{"name":"stage 0 disease","type":"exact"}],"termid":"MONDO:0004647","xrefs":{"Monarch":{"xref_id":"0004647"}}}


id: GO:0085003
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete interaction with host via secreted substance released from stylet (obsolete GO:0085003)","termid":"GO:0085003"}


id: PBO:0058148
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4444-1","termid":"PBO:0058148"}


id: GO:1901380
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.","definition_xrefs":["GOC:BHF","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of potassium ion transport","termid":"GO:0043267"},{"relation_name":"is_a","term_name":"regulation of potassium ion transmembrane transport","termid":"GO:1901379"},{"relation_name":"is_a","term_name":"negative regulation of cation transmembrane transport","termid":"GO:1904063"},{"relation_name":"negatively_regulates","term_name":"potassium ion transmembrane transport","termid":"GO:0071805"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of potassium ion transmembrane transport","synonyms":[{"name":"down regulation of potassium ion transmembrane transport","type":"exact"},{"name":"down-regulation of potassium ion transmembrane transport","type":"exact"},{"name":"downregulation of potassium ion transmembrane transport","type":"exact"},{"name":"inhibition of potassium ion transmembrane transport","type":"narrow"},{"name":"negative regulation of potassium ion membrane transport","type":"exact"}],"termid":"GO:1901380"}


id: PBO:0059756
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO3 pseudogene 30","termid":"PBO:0059756"}


id: PBO:0070748
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L10 pseudogene 4","termid":"PBO:0070748"}


id: PBO:0057879
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3183","termid":"PBO:0057879"}


id: GO:1902728
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:23212449"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of skeletal muscle satellite cell proliferation","termid":"GO:1902724"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of growth factor dependent skeletal muscle satellite cell proliferation","termid":"GO:1902728"}


id: GO:0009647
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The control of plant growth, development, and differentiation in response to growth in darkness.","definition_xrefs":["PMID:15012288"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to absence of light","termid":"GO:0009646"},{"relation_name":"is_a","term_name":"post-embryonic development","termid":"GO:0009791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"skotomorphogenesis","synonyms":[{"name":"etiolation","type":"related"}],"termid":"GO:0009647"}


id: GO:0010790
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic sister chromatid cohesion","termid":"GO:0051177"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"meiotic sister chromatid cohesion involved in meiosis II","termid":"GO:0010790"}


id: FYPO:0002706
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cordycepin than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0002682","FYPO:0000003","FYPO:0005447","FYPO:0001985","FYPO:0000139"],"is_obsolete":false,"name":"resistance to cordycepin","synonyms":[{"name":"resistance to cordycepin during mitotic cell cycle","type":"related"},{"name":"resistance to cordycepin during vegetative growth","type":"exact"},{"name":"resistant to cordycepin","type":"exact"}],"termid":"FYPO:0002706"}


id: MONDO:0008507
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"surface polypeptides, anonymous","secondary_identifiers":["MEDGEN:348354","OMIM:185610","UMLS:C1861417"],"synonyms":[{"name":"Spa2","type":"related"},{"name":"Spa5","type":"related"},{"name":"surface polypeptides, anonymous","type":"exact"}],"termid":"MONDO:0008507","xrefs":{"Monarch":{"xref_id":"0008507"}}}


id: PBO:0088405
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA (cytosine-5-)-methyltransferase","termid":"PBO:0088405"}


id: MONDO:0042974
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Parainfluenza virus type 3 is one of a group of common viruses known as human parainfluenza viruses (HPIV) that cause a variety of respiratory illnesses. Symptoms usually develop between 2 and 7 days from the time of exposure and typically resolve in 7-10 days. Symptoms may include fever, runny nose, and cough. HPIV-3 can also cause bronchiolitis, bronchitis, and pneumonia. Infants and young children are particularly susceptible to HPIV-3 infections, though older adults and those with a weakened immune system are also at risk for complications. HPIVs are usually spread from an infected person to others through coughing, sneezing, and/or touching. There is currently no vaccine to protect against parainfluenza virus infections. Most HPIV infections resolve on their own and do not require special treatment, though medical intervention may be necessary for severe breathing problems. Most adults have antibodies against parainfluenza but can get repeat infections.","definition_xrefs":["GARD:0004215"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respirovirus infectious disease","termid":"MONDO:0005940"},{"relation_name":"is_a","term_name":"parainfluenza infectious disease","termid":"MONDO:0100197"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"parainfluenza virus type 3 infectious disease","secondary_identifiers":["ICD9:079.89","GARD:4215","UMLS:C0276324","SCTID:30270006","MEDGEN:547264"],"synonyms":[{"name":"PIV3","type":"related"},{"name":"human parainfluenza virus type 3","type":"related"},{"name":"human respirovirus 3 caused disease or disorder","type":"exact"},{"name":"human respirovirus 3 disease or disorder","type":"exact"},{"name":"human respirovirus 3 infectious disease","type":"exact"},{"name":"infection caused by human parainfluenza virus 3","type":"related"},{"name":"infection caused by parainfluenza virus 3","type":"related"},{"name":"infection due to human parainfluenza virus 3","type":"exact"},{"name":"infection due to parainfluenza virus 3","type":"related"}],"termid":"MONDO:0042974","xrefs":{"Monarch":{"xref_id":"0042974"}}}


id: GO:0048030
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a disaccharide. Disaccharides are sugars composed of two monosaccharide units.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oligosaccharide binding","termid":"GO:0070492"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"disaccharide binding","termid":"GO:0048030"}


id: MONDO:0006794
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A small vessel vasculitis affecting the skin and/or internal organs. It is characterized by the presence of neutrophils and fibrinoid necrosis in small arteries and venules. It may be idiopathic or the result of drug treatment, infections, food intake, collagen vascular disorders, inflammatory bowel disease, or cancer.","definition_xrefs":["NCIT:C82863"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"type III hypersensitivity disease","termid":"MONDO:0007004"},{"relation_name":"is_a","term_name":"hypersensitivity reaction disease","termid":"MONDO:0000605"},{"relation_name":"is_a","term_name":"vasculitis","termid":"MONDO:0018882"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"hypersensitivity vasculitis","secondary_identifiers":["EFO:1000974","ICD9:446.2","MedDRA:10020764","ICD9:446.29","SCTID:60555002","DOID:9809","ICD9:446.20"],"synonyms":[{"name":"leukocytoclastic vasculitis","type":"exact"}],"termid":"MONDO:0006794","xrefs":{"Monarch":{"xref_id":"0006794"}}}


id: PBO:0048496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanine deaminase","termid":"PBO:0048496"}


id: PBO:0059939
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND2 pseudogene 25","termid":"PBO:0059939"}


id: PBO:0029249
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-actin_filaments_present_in_increased_numbers","termid":"PBO:0029249"}


id: PBO:0079173
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis specific protein Y-linked 2","termid":"PBO:0079173"}


id: GO:0016155
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 10-formyltetrahydrofolate + H2O + NADP+ = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H+ + NADPH.","definition_xrefs":["EC:1.5.1.6","RHEA:10180"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"formyltetrahydrofolate dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R00941","MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN"],"synonyms":[{"name":"10-formyl tetrahydrofolate:NADP oxidoreductase activity","type":"related"},{"name":"10-formyl-H2PtGlu:NADP oxidoreductase activity","type":"related"},{"name":"10-formyl-H4folate dehydrogenase activity","type":"related"},{"name":"10-formyltetrahydrofolate dehydrogenase activity","type":"related"},{"name":"10-formyltetrahydrofolate:NADP+ oxidoreductase activity","type":"related"},{"name":"N10-formyltetrahydrofolate dehydrogenase activity","type":"related"}],"termid":"GO:0016155"}


id: PBO:0116193
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-hydroxyacyl-CoA dehydrogenase, Fox2","termid":"PBO:0116193"}


id: MONDO:0018618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete 46,XY disorder of sexual development due to dihydrotestosterone backdoor pathway biosynthesis defect (obsolete MONDO:0018618)","secondary_identifiers":["Orphanet:443090"],"termid":"MONDO:0018618","xrefs":{"Monarch":{"xref_id":"0018618"}}}


id: MONDO:0010986
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the OTOF gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"},{"relation_name":"is_a","term_name":"auditory neuropathy","termid":"MONDO:0021944"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 9","secondary_identifiers":["DOID:0110535","GARD:22588","UMLS:C1832828","MEDGEN:331376","OMIM:601071"],"synonyms":[{"name":"DFNB9","type":"narrow"},{"name":"NRSD9","type":"narrow"},{"name":"OTOF autosomal recessive nonsyndromic deafness","type":"narrow"},{"name":"auditory neuropathy, autosomal recessive, 1","type":"narrow"},{"name":"auditory neuropathy, nonsyndromic recessive","type":"narrow"},{"name":"autosomal recessive deafness 9","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 9","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness caused by mutation in OTOF","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 9","type":"narrow"},{"name":"autosomal recessive nonsyndromic hearing loss 9","type":"exact"},{"name":"deafness, autosomal recessive 9","type":"narrow"},{"name":"deafness, autosomal recessive type 9","type":"narrow"},{"name":"neurosensory nonsyndromic recessive deafness 9","type":"narrow"}],"termid":"MONDO:0010986","xrefs":{"Monarch":{"xref_id":"0010986"}}}


id: GO:0010015
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support.","definition_xrefs":["ISBN:0877797099","GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plant organ morphogenesis","termid":"GO:1905392"},{"relation_name":"part_of","term_name":"root development","termid":"GO:0048364"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"root morphogenesis","termid":"GO:0010015"}


id: GO:0042400
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.","definition_xrefs":["PMID:11823218","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ectoine metabolic process","termid":"GO:0042399"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0044248"],"is_obsolete":false,"name":"ectoine catabolic process","synonyms":[{"name":"ectoine breakdown","type":"exact"},{"name":"ectoine catabolism","type":"exact"},{"name":"ectoine degradation","type":"exact"}],"termid":"GO:0042400"}


id: MONDO:0005207
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.","definition_xrefs":["NCIT:C2948"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"placenta cancer","termid":"MONDO:0002178"},{"relation_name":"excluded_subClassOf","term_name":"adenocarcinoma","termid":"MONDO:0004970"},{"relation_name":"is_a","term_name":"trophoblastic neoplasm","termid":"MONDO:0002872"},{"relation_name":"is_a","term_name":"germ cell tumor","termid":"MONDO:0005040"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"choriocarcinoma","secondary_identifiers":["SCTID:188188009","UMLS:C0008497","MEDGEN:40278","MESH:D002822","DOID:3594","GARD:6059","ONCOTREE:BCCA","NANDO:2200070","HP:0100768","ICDO:9100/3","EFO:0002893"],"synonyms":[{"name":"chorioblastoma","type":"exact"},{"name":"choriocarcinoma","type":"exact"},{"name":"choriocarcinoma (disease)","type":"exact"},{"name":"choriocarcinoma, malignant","type":"exact"},{"name":"chorioepithelioma","type":"exact"},{"name":"chorion carcinoma","type":"exact"},{"name":"chorionic carcinoma","type":"exact"}],"termid":"MONDO:0005207","xrefs":{"Monarch":{"xref_id":"0005207"}}}


id: GO:0005095
data:
  {"annotated_genes":["SJAG_04203"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[116049],"is_not":false,"summary":null,"term":"GO:0005095"}]},"cv_name":"molecular_function","definition":"Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme inhibitor activity","termid":"GO:0004857"},{"relation_name":"is_a","term_name":"GTPase regulator activity","termid":"GO:0030695"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04203":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0004857"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140678","GO:0030234","GO:0003674","GO:0004857","GO:0098772"],"is_obsolete":false,"name":"GTPase inhibitor activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"GIP","type":"broad"}],"termid":"GO:0005095","terms_by_termid":{"GO:0005095":null}}


id: PBO:0084156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates","termid":"PBO:0084156"}


id: PBO:0086861
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C","termid":"PBO:0086861"}


id: GO:0090533
data:
  {"annotated_genes":["SJAG_00516","SJAG_00136","SJAG_03962","SJAG_01817","SJAG_00212","SJAG_02023","SJAG_01397","SJAG_01471","SJAG_01913","SJAG_03406","SJAG_04955","SJAG_05294","SJAG_02782","SJAG_04015","SJAG_01447"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[99702,61800,89922,95407,91814,95588,103662],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000220"},{"annotations":[118466,96367,98672,102422,70904,109620,87796,60514],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000221"}]},"cv_name":"cellular_component","definition":"Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ATPase dependent transmembrane transport complex","termid":"GO:0098533"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00136":null,"SJAG_00212":null,"SJAG_00516":null,"SJAG_01397":null,"SJAG_01447":null,"SJAG_01471":null,"SJAG_01817":null,"SJAG_01913":null,"SJAG_02023":null,"SJAG_02782":null,"SJAG_03406":null,"SJAG_03962":null,"SJAG_04015":null,"SJAG_04955":null,"SJAG_05294":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"cation-transporting ATPase complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0090533","terms_by_termid":{"GO:0000220":null,"GO:0000221":null}}


id: GO:0062021
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle.","definition_xrefs":["PMID:29358048","GOC:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete mitotic cohesin dsDNA (leading strand) loading (obsolete GO:0062021)","termid":"GO:0062021"}


id: PBO:0036500
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-like protein modifier Urm1 (predicted)","termid":"PBO:0036500"}


id: PBO:0069777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1061, pseudogene","termid":"PBO:0069777"}


id: PBO:0003617
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TatD homolog (predicted)","termid":"PBO:0003617"}


id: GO:0032883
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of chitin metabolic process","termid":"GO:0032882"},{"relation_name":"is_a","term_name":"regulation of polysaccharide biosynthetic process","termid":"GO:0032885"},{"relation_name":"regulates","term_name":"chitin biosynthetic process","termid":"GO:0006031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"regulation of chitin biosynthetic process","synonyms":[{"name":"regulation of chitin anabolism","type":"exact"},{"name":"regulation of chitin biosynthesis","type":"related"},{"name":"regulation of chitin formation","type":"exact"},{"name":"regulation of chitin synthesis","type":"exact"}],"termid":"GO:0032883"}


id: MONDO:1010669
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Myeloperoxidase deficiency that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloperoxidase deficiency, non-human animal","termid":"MONDO:1010086"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myeloperoxidase deficiency, dog","secondary_identifiers":["OMIA:002028-9615"],"termid":"MONDO:1010669","xrefs":{"Monarch":{"xref_id":"1010669"}}}


id: PBO:0001548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial TOM complex subunit Tom70 (predicted)","termid":"PBO:0001548"}


id: PBO:0040676
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCAR1 pseudogene 1","termid":"PBO:0040676"}


id: PBO:0061377
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleophosmin 1 pseudogene 37","termid":"PBO:0061377"}


id: PBO:0082255
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication","termid":"PBO:0082255"}


id: PBO:0030868
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_actin_cytoskeleton_organization","termid":"PBO:0030868"}


id: PBO:0025525
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein Hsp104","termid":"PBO:0025525"}


id: MONDO:0030695
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0005027","MONDO:0700092"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy 100","secondary_identifiers":["OMIM:619777","DOID:0070386","MEDGEN:1809351","UMLS:C5676932"],"synonyms":[{"name":"DEE100","type":"exact"},{"name":"developmental and epileptic encephalopathy 100","type":"exact"}],"termid":"MONDO:0030695","xrefs":{"Monarch":{"xref_id":"0030695"}}}


id: MONDO:0012848
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Meckel syndrome in which the cause of the disease is a mutation in the CC2D2A gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Meckel syndrome","termid":"MONDO:0018921"},{"relation_name":"is_a","term_name":"polydactyly-syndactyly-triphalangism","termid":"MONDO:0800066"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Meckel syndrome, type 6","secondary_identifiers":["MESH:C567365","GARD:15548","DOID:0070120","UMLS:C2676790","MEDGEN:382942","OMIM:612284"],"synonyms":[{"name":"CC2D2A Meckel syndrome","type":"exact"},{"name":"MKS6","type":"exact"},{"name":"Meckel syndrome 6","type":"related"},{"name":"Meckel syndrome caused by mutation in CC2D2A","type":"exact"},{"name":"Meckel syndrome, type 6","type":"exact"},{"name":"Meckel-Gruber syndrome, type 6","type":"exact"}],"termid":"MONDO:0012848","xrefs":{"Monarch":{"xref_id":"0012848"}}}


id: PBO:0029605
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_transporter_activity","termid":"PBO:0029605"}


id: PBO:0027056
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cell_wall_galactomannan_level","termid":"PBO:0027056"}


id: MONDO:0033007
data:
  {"annotated_genes":["SJAG_04182"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84997],"is_not":false,"summary":null,"term":"MONDO:0033007"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Galloway-Mowat syndrome","termid":"MONDO:0009627"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04182":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Galloway-Mowat syndrome 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4540266","DOID:0080245","GARD:16247","OMIM:617729","MEDGEN:1627611"],"synonyms":[{"name":"GAMOS3","type":"related"},{"name":"Galloway-Mowat syndrome 3","type":"exact"}],"termid":"MONDO:0033007","terms_by_termid":{"MONDO:0033007":null},"xrefs":{"Monarch":{"xref_id":"0033007"}}}


id: MONDO:0017720
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASES system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS.","definition_xrefs":["Orphanet:309152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gangliosidosis","termid":"MONDO:0017719"},{"relation_name":"is_a","term_name":"inherited neurodegenerative disorder","termid":"MONDO:0024237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0002525","MONDO:0005066","MONDO:0002561"],"is_obsolete":false,"name":"GM2 gangliosidosis","secondary_identifiers":["DOID:3321","NANDO:1200070","MEDGEN:78656","NANDO:2200559","icd11.foundation:1513691830","UMLS:C0268274","GARD:21323","SCTID:33316007","ICD10CM:E75.0","MESH:D020143"],"synonyms":[{"name":"GM2-gangliosidosis, B, B1, AB variant","type":"related"},{"name":"GM>2< gangliosidosis","type":"exact"},{"name":"gangliosidosis GM2","type":"exact"}],"termid":"MONDO:0017720","xrefs":{"Monarch":{"xref_id":"0017720"}}}


id: MONDO:0020293
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete ascending aorta anomaly (obsolete MONDO:0020293)","secondary_identifiers":["Orphanet:98725"],"termid":"MONDO:0020293","xrefs":{"Monarch":{"xref_id":"0020293"}}}


id: PBO:0065420
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome 20S subunit beta 7","termid":"PBO:0065420"}


id: PBO:0049337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTF2H2 family member C, copy 2","termid":"PBO:0049337"}


id: PBO:0018042
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotic chromosome segregation protein Csi1","termid":"PBO:0018042"}


id: PBO:0085729
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity","termid":"PBO:0085729"}


id: MONDO:0013023
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"orofacial cleft","termid":"MONDO:0000358"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"orofacial cleft 12","secondary_identifiers":["UMLS:C2748505","MEDGEN:411596","MESH:C567548","OMIM:612858","DOID:0080405"],"synonyms":[{"name":"OFC12","type":"exact"},{"name":"cleft lip with or without cleft palate, nonsyndromic, 12","type":"related"},{"name":"orofacial cleft 12","type":"exact"}],"termid":"MONDO:0013023","xrefs":{"Monarch":{"xref_id":"0013023"}}}


id: GO:0072072
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"connective tissue development","termid":"GO:0061448"},{"relation_name":"is_a","term_name":"kidney mesenchyme development","termid":"GO:0072074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"kidney stroma development","termid":"GO:0072072"}


id: PBO:0076351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptotagmin 15B","termid":"PBO:0076351"}


id: PBO:0087560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of signal peptidase complex; complex catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; inhibits SRP-independent translocation into the ER with STE24; homologous to mammalian SPC25; other members of the complex are Spc1p, Spc1p, and Sec11p","termid":"PBO:0087560"}


id: PBO:0042782
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centrosomal protein 120","termid":"PBO:0042782"}


id: PBO:0088285
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol-4 kinase plasma membrane scaffold Erf3 partner Ypp1","termid":"PBO:0088285"}


id: GO:0046247
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoprenoid catabolic process","termid":"GO:0008300"},{"relation_name":"is_a","term_name":"terpene metabolic process","termid":"GO:0042214"},{"relation_name":"is_a","term_name":"hydrocarbon catabolic process","termid":"GO:0120253"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"terpene catabolic process","synonyms":[{"name":"terpene breakdown","type":"exact"},{"name":"terpene catabolism","type":"exact"},{"name":"terpene degradation","type":"exact"}],"termid":"GO:0046247"}


id: MONDO:0005611
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The most common morphologic subtype of urinary bladder carcinoma (over 90% of cases). It arises from the transitional epithelium. It most often affects males in their sixth and seventh decades of life. Hematuria is the most common symptom at presentation. Pathologic stage is the strongest predictor of survival.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urinary bladder carcinoma","termid":"MONDO:0004986"},{"relation_name":"is_a","term_name":"urothelial carcinoma","termid":"MONDO:0040679"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"bladder transitional cell carcinoma","secondary_identifiers":["DOID:4006","EFO:0006544","MEDGEN:76013","NCIT:C39851","ONCOTREE:BLCA","SCTID:255109008","UMLS:C0279680"],"synonyms":[{"name":"BLCA","type":"related"},{"name":"bladder transitional cell carcinoma","type":"exact"},{"name":"bladder urothelial cancer","type":"exact"},{"name":"bladder urothelial carcinoma","type":"exact"},{"name":"transitional cell carcinoma of bladder","type":"exact"},{"name":"transitional cell carcinoma of the urinary bladder","type":"exact"},{"name":"urinary bladder transitional cell carcinoma","type":"exact"},{"name":"urinary bladder urothelial carcinoma","type":"exact"},{"name":"urothelial bladder carcinoma","type":"exact"},{"name":"urothelial carcinoma of the urinary bladder","type":"exact"}],"termid":"MONDO:0005611","xrefs":{"Monarch":{"xref_id":"0005611"}}}


id: PBO:0045126
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DM1 locus, WD repeat containing","termid":"PBO:0045126"}


id: MONDO:0015462
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thin ribs-tubular bones-dysmorphism syndrome","secondary_identifiers":["MEDGEN:419105","UMLS:C2931543","MESH:C537595","GARD:18727","Orphanet:1506"],"synonyms":[{"name":"Sharma-Kapoor-Ramji syndrome","type":"exact"}],"termid":"MONDO:0015462","xrefs":{"Monarch":{"xref_id":"0015462"}}}


id: GO:1900179
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process.","definition_xrefs":["GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of small molecule metabolic process","termid":"GO:0062013"},{"relation_name":"is_a","term_name":"regulation of aflatoxin biosynthetic process","termid":"GO:1900177"},{"relation_name":"is_a","term_name":"positive regulation of secondary metabolite biosynthetic process","termid":"GO:1900378"},{"relation_name":"positively_regulates","term_name":"aflatoxin biosynthetic process","termid":"GO:0045122"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0019748"},{"rel_name":"positively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"positive regulation of aflatoxin biosynthetic process","synonyms":[{"name":"activation of aflatoxin anabolism","type":"narrow"},{"name":"activation of aflatoxin biosynthesis","type":"narrow"},{"name":"activation of aflatoxin biosynthetic process","type":"narrow"},{"name":"activation of aflatoxin formation","type":"narrow"},{"name":"activation of aflatoxin synthesis","type":"narrow"},{"name":"positive regulation of aflatoxin anabolism","type":"exact"},{"name":"positive regulation of aflatoxin biosynthesis","type":"exact"},{"name":"positive regulation of aflatoxin formation","type":"exact"},{"name":"positive regulation of aflatoxin synthesis","type":"exact"},{"name":"up regulation of aflatoxin anabolism","type":"exact"},{"name":"up regulation of aflatoxin biosynthesis","type":"exact"},{"name":"up regulation of aflatoxin biosynthetic process","type":"exact"},{"name":"up regulation of aflatoxin formation","type":"exact"},{"name":"up regulation of aflatoxin synthesis","type":"exact"},{"name":"up-regulation of aflatoxin anabolism","type":"exact"},{"name":"up-regulation of aflatoxin biosynthesis","type":"exact"},{"name":"up-regulation of aflatoxin biosynthetic process","type":"exact"},{"name":"up-regulation of aflatoxin formation","type":"exact"},{"name":"up-regulation of aflatoxin synthesis","type":"exact"},{"name":"upregulation of aflatoxin anabolism","type":"exact"},{"name":"upregulation of aflatoxin biosynthesis","type":"exact"},{"name":"upregulation of aflatoxin biosynthetic process","type":"exact"},{"name":"upregulation of aflatoxin formation","type":"exact"},{"name":"upregulation of aflatoxin synthesis","type":"exact"}],"termid":"GO:1900179"}


id: PBO:0042551
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin dependent kinase 14","termid":"PBO:0042551"}


id: PBO:0070807
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 37","termid":"PBO:0070807"}


id: PBO:0070286
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, variant U1 small nuclear 27","termid":"PBO:0070286"}


id: GO:0031235
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only.","definition_xrefs":["GOC:dos","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete intrinsic component of the cytoplasmic side of the plasma membrane (obsolete GO:0031235)","synonyms":[{"name":"intrinsic to cytoplasmic side of plasma membrane","type":"narrow"},{"name":"intrinsic to internal leaflet of plasma membrane","type":"exact"},{"name":"intrinsic to internal side of plasma membrane","type":"exact"}],"termid":"GO:0031235"}


id: PBO:0091658
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane ferric-chelate reductase Frp1","termid":"PBO:0091658"}


id: PBO:0008883
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mating-type M-specific polypeptide Mm/Mi","termid":"PBO:0008883"}


id: MONDO:0850302
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A meningioma that arises within the cranial cavity.","definition_xrefs":["DOID:0080842"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meningioma","termid":"MONDO:0016642"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intracranial meningioma","secondary_identifiers":["MEDGEN:83891","UMLS:C0349604","NCIT:C4656","DOID:0060106"],"synonyms":[{"name":"brain meningioma","type":"exact"},{"name":"brain meningioma (disease)","type":"exact"},{"name":"meningioma (disease) of brain","type":"exact"}],"termid":"MONDO:0850302","xrefs":{"Monarch":{"xref_id":"0850302"}}}


id: PBO:0053739
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 964","termid":"PBO:0053739"}


id: PBO:0045470
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dopamine receptor D5 pseudogene 2","termid":"PBO:0045470"}


id: PBO:0028928
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_septum_orientation","termid":"PBO:0028928"}


id: MONDO:0014159
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Spectrin-associated autosomal recessive cerebellar ataxia is a rare, genetic neurological disease, due to SPTBN2 mutations, characterized by global development delay in infancy, followed by childhood-onset gait ataxia with limb dysmetria and dysdiadochokinesia, mild to severe intellectual disability, development of cerebellar atrophy, and abnormal eye movements (including a convergent squint, hypometric saccades, jerky pursuit movements and incomplete range of movement).","definition_xrefs":["Orphanet:352403"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive cerebellar ataxia","termid":"MONDO:0015244"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005559"],"is_obsolete":false,"name":"autosomal recessive spinocerebellar ataxia 14","secondary_identifiers":["DOID:0080058","SCTID:763351003","UMLS:C4706415","GARD:17516","OMIM:615386","MEDGEN:1636182"],"synonyms":[{"name":"Ataxie spinocérébelleuse à début infantile avec retard psychomoteur","type":"exact"},{"name":"SCAR14","type":"exact"},{"name":"SPARCA","type":"exact"},{"name":"SPARCA1","type":"exact"},{"name":"SPTBN2 autosomal recessive cerebellar ataxia","type":"exact"},{"name":"autosomal recessive cerebellar ataxia caused by mutation in SPTBN2","type":"exact"},{"name":"autosomal recessive cerebellar ataxia-cognitive defect syndrome","type":"exact"},{"name":"autosomal recessive spinocerebellar ataxia type 14","type":"exact"},{"name":"cerebellar ataxia, autosomal recessive, spectrin-associated, 1","type":"related"},{"name":"infantile-onset spinocerebellar ataxia-psychomotor delay syndrome","type":"exact"},{"name":"spectrin-associated autosomal recessive cerebellar ataxia","type":"related"},{"name":"spectrin-associated autosomal recessive cerebellar ataxia type 1","type":"exact"},{"name":"spinocerebellar ataxia, autosomal recessive 14","type":"related"},{"name":"spinocerebellar ataxia, autosomal recessive type 14","type":"exact"}],"termid":"MONDO:0014159","xrefs":{"Monarch":{"xref_id":"0014159"}}}


id: PBO:0088046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin-conjugating enzyme that regulates gluconeogenesis; negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro","termid":"PBO:0088046"}


id: PR:Q96WV6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A mucin-17 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02553","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBPJ4664.02","secondary_identifiers":["UniProtKB:Q96WV6"],"synonyms":[{"name":"Spom972h-MUC17","type":"exact"}],"termid":"PR:Q96WV6"}


id: GO:0150118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization.","definition_xrefs":["GOC:aruk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular component organization","termid":"GO:0051129"},{"relation_name":"is_a","term_name":"regulation of cell-substrate junction organization","termid":"GO:0150116"},{"relation_name":"negatively_regulates","term_name":"cell-substrate junction organization","termid":"GO:0150115"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cell-substrate junction organization","termid":"GO:0150118"}


id: GO:0035088
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.","definition_xrefs":["GOC:mah","PMID:10934483","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment or maintenance of bipolar cell polarity","termid":"GO:0061245"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007163"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007163","GO:0008150"],"is_obsolete":false,"name":"establishment or maintenance of apical/basal cell polarity","termid":"GO:0035088"}


id: PBO:0003086
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aminotransferase (predicted)","termid":"PBO:0003086"}


id: PR:P33532
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- bsu1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P33532"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vitamin B6 transporter bsu1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17A2.01","synonyms":[{"name":"Spom972h-bsu1","type":"exact"},{"name":"amiloride transporter car1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"changed amiloride resistance protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"vitamin B6 uptake protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P33532"}


id: PR:O13781
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC17G6.03 gene.","definition_xrefs":["UniProtKB:O13781","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C17G6.03 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17G6.03","synonyms":[{"name":"Spom972h-SPAC17G6.03","type":"exact"}],"termid":"PR:O13781"}


id: GO:0045545
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.","definition_xrefs":["GOC:go_curators","PMID:9355727"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteoglycan binding","termid":"GO:0043394"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"syndecan binding","termid":"GO:0045545"}


id: MONDO:0024953
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A departure from the normal gait in animals.","definition_xrefs":["MESH:D007794"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human animal disease","termid":"MONDO:0005583"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lameness, non-human animal","synonyms":[{"name":"Gait disorder, animal","type":"related"},{"name":"Gait disorders, animal","type":"related"},{"name":"Lamenesses, animal","type":"related"},{"name":"animal Gait disorder","type":"related"},{"name":"animal Gait disorders","type":"related"},{"name":"animal Lamenesses","type":"related"},{"name":"animal lameness","type":"related"},{"name":"disorder, animal Gait","type":"related"},{"name":"disorders, animal Gait","type":"related"}],"termid":"MONDO:0024953","xrefs":{"Monarch":{"xref_id":"0024953"}}}


id: PBO:0028854
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_RNA_level_during_glucose_starvation","termid":"PBO:0028854"}


id: PR:P48383
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sak1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P48383"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein sak1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3G9.14","synonyms":[{"name":"Spom972h-sak1","type":"exact"}],"termid":"PR:P48383"}


id: MONDO:0011430
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cataract that has material basis in heterozygous mutation in the CRYGC gene on chromosome 2q33.","definition_xrefs":["Orphanet:98984"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"cataract","termid":"MONDO:0005129"},{"relation_name":"is_a","term_name":"early-onset non-syndromic cataract","termid":"MONDO:0011060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"pulverulent cataract","secondary_identifiers":["UMLS:C1833118","icd11.foundation:1046743385","GARD:16884","MEDGEN:318793","Orphanet:98986","MESH:C565133"],"synonyms":[{"name":"Coppock-like cataract","type":"exact"},{"name":"dusty cataract","type":"exact"},{"name":"pulverulent cataract","type":"exact"}],"termid":"MONDO:0011430","xrefs":{"Monarch":{"xref_id":"0011430"}}}


id: MOD:01736
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-128 reporter+balance group.","definition_xrefs":["Unimod:737"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent acylated residue","termid":"MOD:01715"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-128 reporter+balance reagent acylated residue","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01736"}


id: PBO:0038614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ACD shelterin complex subunit and telomerase recruitment factor","termid":"PBO:0038614"}


id: GO:0035354
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).","definition_xrefs":["PMID:17889651","GOC:add","GOC:signaling","PMID:21481769"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane signaling receptor complex","termid":"GO:0098802"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0005575","GO:0032991"],"is_obsolete":false,"name":"Toll-like receptor 1-Toll-like receptor 2 protein complex","secondary_identifiers":["GO:0038125"],"synonyms":[{"name":"TLR1-TLR2 protein complex","type":"exact"},{"name":"TLR1:TLR2 complex","type":"exact"},{"name":"TLR2:TLR1 heterodimer","type":"exact"},{"name":"toll-like receptor TLR1:TLR2 heterodimeric complex","type":"exact"}],"termid":"GO:0035354"}


id: PBO:0031128
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_ammonia_nitrogen_source","termid":"PBO:0031128"}


id: PBO:0060304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MYL12A pseudogene 1","termid":"PBO:0060304"}


id: PBO:0074505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear RNA activating complex polypeptide 4","termid":"PBO:0074505"}


id: FYPO:0000536
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein transport during vegetative growth","termid":"FYPO:0000540"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"abnormal protein secretion during vegetative growth","synonyms":[{"name":"abnormal protein secretion during mitotic cell cycle","type":"related"},{"name":"protein secretion: abnormal","type":"related"}],"termid":"FYPO:0000536"}


id: GO:0033967
data:
  {"annotated_genes":["SJAG_00943","SJAG_06613","SJAG_02553","SJAG_02350","SJAG_01369","SJAG_03234","SJAG_04527"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73139,109949],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000494"},{"annotations":[101921],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106410"},{"annotations":[104532,90850,115050,113233],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034965"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving box C/D type small nucleolar RNA.","definition_xrefs":["GOC:mah","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sno(s)RNA metabolic process","termid":"GO:0016074"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00943":null,"SJAG_01369":null,"SJAG_02350":null,"SJAG_02553":null,"SJAG_03234":null,"SJAG_04527":null,"SJAG_06613":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016074"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0016074","GO:0008150"],"is_obsolete":false,"name":"box C/D sno(s)RNA metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"box C/D sRNA metabolic process","type":"narrow"},{"name":"box C/D snoRNA metabolic process","type":"narrow"}],"termid":"GO:0033967","terms_by_termid":{"GO:0000494":null,"GO:0034965":null,"GO:0106410":null}}


id: PBO:0082921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytochrome c isoform 2, expressed under hypoxic conditions; also known as iso-2-cytochrome c; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; protein abundance increases in response to DNA replication stress; CYC7 has a paralog, CYC1, that arose from the whole genome duplication","termid":"PBO:0082921"}


id: PBO:0111297
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase chadoprop types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"biogrid_version","termid":"PBO:0111297"}


id: MONDO:0008829
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chylous ascites is a rare form of ascites caused by accumulation of lymph in the peritoneal cavity, usually due to intra-abdominal malignancy, liver cirrhosis or abdominal surgery complications, and present with painless but progressive abdominal distension, dyspnea and weight gain.","definition_xrefs":["Orphanet:1160"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary lymphedema","termid":"MONDO:0019175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"chylous ascites","secondary_identifiers":["UMLS:C0008732","MESH:D002915","icd11.foundation:768846885","MedDRA:10003446","NCIT:C34482","SCTID:52985009","MEDGEN:969","ICD9:457.8","OMIM:208300","GARD:1359"],"synonyms":[{"name":"ascites, chylous","type":"related"},{"name":"congenital chylous ascites","type":"related"}],"termid":"MONDO:0008829","xrefs":{"Monarch":{"xref_id":"0008829"}}}


id: GO:0000919
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast.","definition_xrefs":["GOC:clt"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle process","termid":"GO:0022402"},{"relation_name":"is_a","term_name":"cellular component assembly","termid":"GO:0022607"},{"relation_name":"part_of","term_name":"cytokinesis by cell plate formation","termid":"GO:0000911"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0044085","GO:0008150"],"is_obsolete":false,"name":"cell plate assembly","synonyms":[{"name":"cell plate formation","type":"related"}],"termid":"GO:0000919"}


id: GO:0048171
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.","definition_xrefs":["GOC:jid","PMID:11891290"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of long-term neuronal synaptic plasticity","termid":"GO:0048169"},{"relation_name":"is_a","term_name":"negative regulation of neurogenesis","termid":"GO:0050768"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of long-term neuronal synaptic plasticity","synonyms":[{"name":"down regulation of long-term neuronal synaptic plasticity","type":"exact"},{"name":"down-regulation of long-term neuronal synaptic plasticity","type":"exact"},{"name":"downregulation of long-term neuronal synaptic plasticity","type":"exact"},{"name":"inhibition of long-term neuronal synaptic plasticity","type":"narrow"}],"termid":"GO:0048171"}


id: FYPO:0006566
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a normal proportion of cells in the population remains viable under conditions of sulfur starvation.","definition_xrefs":["PMID:9372444","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal phenotype","termid":"FYPO:0000257"},{"relation_name":"is_a","term_name":"cell population viability","termid":"FYPO:0002057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002057","FYPO:0000257"],"is_obsolete":false,"name":"normal viability upon sulfur starvation","synonyms":[{"name":"normal cell population viability upon sulfur starvation","type":"exact"},{"name":"normal viability upon sulphur starvation","type":"exact"}],"termid":"FYPO:0006566"}


id: PBO:0091717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinetochore protein Mis19/Eic1","termid":"PBO:0091717"}


id: PBO:0062710
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 51 subfamily H member 2 pseudogene","termid":"PBO:0062710"}


id: GO:0031803
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 6 metabotropic glutamate receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled glutamate receptor binding","termid":"GO:0035256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"type 6 metabotropic glutamate receptor binding","synonyms":[{"name":"type 6 metabotropic glutamate receptor ligand","type":"narrow"}],"termid":"GO:0031803"}


id: PBO:0043593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type XXIII alpha 1 chain","termid":"PBO:0043593"}


id: MONDO:0005413
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cystic fibrosis associated meconium ileum is a thickening and congestion of the meconium in the ileum in newborns, often the first sign of cystic fibrosis. In cystic fibrosis, the meconium can form a bituminous black-green mechanical obstruction in a segment of the ileum. Beyond this there may be a few separate grey-white globular pellets. Below this level, the bowel is a narrow and empty micro-colon. Above the level of the obstruction, there are several loops of hypertrophied bowel distended with fluid. No meconium is passed, and abdominal distension and vomiting appear soon after birth. About 20% of cases of cystic fibrosis present with meconium ileus, while approximately 20% of one series of cases of meconium ileus did not have cystic fibrosis. The presence of meconium ileus is not related to the severity of the cystic fibrosis.","definition_xrefs":["EFO:0004608"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"cystic fibrosis","termid":"MONDO:0009061"},{"relation_name":"is_a","term_name":"meconium ileus","termid":"MONDO:0054868"},{"relation_name":"is_a","term_name":"perinatal disease","termid":"MONDO:0100086"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"cystic fibrosis associated meconium ileus","secondary_identifiers":["MEDGEN:639765","UMLS:C0546982"],"synonyms":[{"name":"cystic fibrosis associated meconium ileum","type":"exact"}],"termid":"MONDO:0005413","xrefs":{"Monarch":{"xref_id":"0005413"}}}


id: PBO:0083081
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Divalent metal ion transporter; broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins","termid":"PBO:0083081"}


id: GO:0120331
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process pertaining to the initial formation of an endothelial tube.","definition_xrefs":["PMID:23239824","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial tube formation","termid":"GO:0072175"},{"relation_name":"part_of","term_name":"endothelial tube morphogenesis","termid":"GO:0061154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endothelial tube formation","termid":"GO:0120331"}


id: PBO:0078323
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA aspartic acid methyltransferase 1","termid":"PBO:0078323"}


id: GO:0018415
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.","definition_xrefs":["RESID:AA0292"],"gene_count":0,"genotype_count":0,"name":"obsolete iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide (obsolete GO:0018415)","synonyms":[{"name":"iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide","type":"exact"}],"termid":"GO:0018415"}


id: MONDO:0009363
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hydrocephaly-tall stature-joint laxity syndrome is a multiple congenital anomalies syndrome described in two sisters and characterized by the presence of hydrocephalus (onset in infancy), tall stature, joint laxity, and thoracolumbar kyphosis. There have been no further descriptions in the literature since 1989.","definition_xrefs":["Orphanet:2181"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydrocephaly-tall stature-joint laxity syndrome","secondary_identifiers":["MESH:C535770","SCTID:732926009","OMIM:236660","UMLS:C1856051","MEDGEN:383828","GARD:1666"],"synonyms":[{"name":"Daish Hardman Lamont syndrome","type":"related"},{"name":"Daish-Hardman-Lamont syndrome","type":"exact"},{"name":"hydrocephalus, tall stature, JOINT laxity, and kyphoscoliosis","type":"related"},{"name":"hydrocephalus, tall stature, joint laxity and kyphoscoliosis","type":"related"},{"name":"hydrocephaly - tall stature - joint laxity","type":"related"}],"termid":"MONDO:0009363","xrefs":{"Monarch":{"xref_id":"0009363"}}}


id: PBO:0006195
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-modified_by","termid":"PBO:0006195"}


id: MONDO:1011127
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Testicular regression syndrome that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"testicular regression syndrome, non-human animal","termid":"MONDO:1010281"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testicular regression syndrome, horse","secondary_identifiers":["OMIA:001535-9796"],"termid":"MONDO:1011127","xrefs":{"Monarch":{"xref_id":"1011127"}}}


id: PBO:0067470
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 600, pseudogene","termid":"PBO:0067470"}


id: MONDO:0005763
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with viruses of the family flaviviridae.","definition_xrefs":["MESH:D018178"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary viral infectious disease","termid":"MONDO:0100329"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Flaviviridae infectious disease","secondary_identifiers":["EFO:0007274","SCTID:111865007"],"synonyms":[{"name":"Flaviviridae caused disease or disorder","type":"exact"},{"name":"Flaviviridae disease or disorder","type":"exact"}],"termid":"MONDO:0005763","xrefs":{"Monarch":{"xref_id":"0005763"}}}


id: PR:Q9UTJ3-2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A meiotic expression up-regulated protein 1/2 (Schizosaccharomyces pombe 972h-) that is a translation product of some mRNA giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UTJ3-2.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UTJ3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic expression up-regulated protein 1/2 (Schizosaccharomyces pombe 972h-)","termid":"PR:Q9UTJ3"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic expression up-regulated protein 1/2 isoform meu1-2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.01","secondary_identifiers":["UniProtKB:Q9UTJ3-2"],"synonyms":[{"name":"Spom972h-meu1-1/iso:meu1-2","type":"exact"},{"name":"meiotic expression up-regulated protein 1/2 isoform SPAC1556.06.2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"meiotic expression up-regulated protein 1/2 isoform SPAC1556.06b (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"meiotic expression up-regulated protein 1/2 isoform meu2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UTJ3-2"}


id: MONDO:0030480
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"hearing loss, autosomal recessive 119","secondary_identifiers":["OMIM:619615","UMLS:C5562023","MEDGEN:1794233"],"synonyms":[{"name":"DFNB119","type":"exact"},{"name":"deafness, autosomal recessive 119","type":"narrow"}],"termid":"MONDO:0030480","xrefs":{"Monarch":{"xref_id":"0030480"}}}


id: GO:0071980
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.","definition_xrefs":["PMID:18461074"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell gliding","termid":"GO:0071976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell surface adhesin-mediated gliding motility","termid":"GO:0071980"}


id: PBO:0027625
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_cell_cycle_arrest_in_mitotic_G1_phase_in_response_to_nitrogen_starvation","termid":"PBO:0027625"}


id: PBO:0055250
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2677","termid":"PBO:0055250"}


id: GO:1905811
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:27779093"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of synapse pruning","termid":"GO:1905807"},{"relation_name":"is_a","term_name":"regulation of excitatory synapse pruning","termid":"GO:1905810"},{"relation_name":"negatively_regulates","term_name":"excitatory synapse pruning","termid":"GO:1905805"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of excitatory synapse pruning","synonyms":[{"name":"down regulation of excitatory synapse disassembly","type":"exact"},{"name":"down-regulation of excitatory synapse disassembly","type":"exact"},{"name":"downregulation of excitatory synapse disassembly","type":"exact"},{"name":"inhibition of excitatory synapse disassembly","type":"narrow"},{"name":"regulation of synapse clearance","type":"broad"},{"name":"regulation of synapse disassembly","type":"broad"},{"name":"regulation of synapse elimination","type":"broad"},{"name":"regulation of synapse removal","type":"broad"}],"termid":"GO:1905811"}


id: FYPO:0000282
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A viability phenotype observed in the vegetative growth phase of the life cycle in which a cell is able to survive at a high temperature.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete viable cell at high temperature (obsolete FYPO:0000282)","synonyms":[{"name":"cell viable at high temperature","type":"exact"},{"name":"viable cell at high temperature during mitotic cell cycle","type":"related"},{"name":"viable cell at high temperature during vegetative growth","type":"exact"}],"termid":"FYPO:0000282"}


id: GO:0070181
data:
  {"annotated_genes":["SJAG_04281","SJAG_01468","SJAG_01132","SJAG_00253","SJAG_01387"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70548,70600,77576,96388,115759],"is_not":false,"summary":null,"term":"GO:0070181"}]},"cv_name":"molecular_function","definition":"Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.","definition_xrefs":["GOC:elh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA binding","termid":"GO:0019843"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00253":null,"SJAG_01132":null,"SJAG_01387":null,"SJAG_01468":null,"SJAG_04281":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0003723","GO:0005488"],"is_obsolete":false,"name":"small ribosomal subunit rRNA binding","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"18S rRNA binding","type":"exact"},{"name":"SSU rRNA binding","type":"exact"}],"termid":"GO:0070181","terms_by_termid":{"GO:0070181":null}}


id: GO:0070334
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.","definition_xrefs":["PMID:7556090","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005886"],"is_obsolete":false,"name":"alpha6-beta4 integrin-laminin 5 complex","synonyms":[{"name":"ITGA6-ITGB4-LAMA5 complex","type":"narrow"},{"name":"alpha6-beta4 integrin-laminin-332 complex","type":"exact"}],"termid":"GO:0070334"}


id: MONDO:0004802
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition characterized by infiltration of the lung with eosinophils due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.","definition_xrefs":["MESH:D011657"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypereosinophilic syndrome","termid":"MONDO:0015691"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005267","MONDO:0005570"],"is_obsolete":false,"name":"pulmonary eosinophilia","secondary_identifiers":["DOID:9498","SCTID:367542003","MEDGEN:46208","UMLS:C0034068","icd11.foundation:544479555","ICD9:518.3"],"termid":"MONDO:0004802","xrefs":{"Monarch":{"xref_id":"0004802"}}}


id: MOD:00463
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-tryptophan residue to 3'-hydroxy-L-kynurenine.","definition_xrefs":["PubMed:9252331","Unimod:350#W","OMSSA:58"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon oxygenated residue","termid":"MOD:00679"},{"relation_name":"is_a","term_name":"modified L-tryptophan residue","termid":"MOD:00918"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3'-hydroxy-L-kynurenine","synonyms":[{"name":"Trp->Hydroxykynurenin","type":"related"},{"name":"hydroxykynureninw","type":"exact"},{"name":"tryptophan oxidation to hydroxykynurenin","type":"related"}],"termid":"MOD:00463"}


id: PBO:0089181
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TIM22 inner membrane protein insertion complex subunit Tim22","termid":"PBO:0089181"}


