# terms

id: MONDO:0019787
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Severe-immune mediated enteropathy describes a variety of intestinal disorders that can range from a serious, early-onset systemic disease (IPEX) to a mild isolated gastrointestinal disease. In children it manifests with severe diarrhea and dehydration in the presence of characteristic antibodies (anti-enterocyte and anti-goblet cell) and in adults with chronic diarrhea, malabsorption and weight loss.","definition_xrefs":["Orphanet:94075"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune disorder of gastrointestinal tract","termid":"MONDO:0000588"},{"relation_name":"is_a","term_name":"malabsorption syndrome","termid":"MONDO:0020598"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0005046"],"is_obsolete":false,"name":"autoimmune enteropathy","secondary_identifiers":["SCTID:235728001","MEDGEN:83322","MESH:C538273","GARD:8689","NCIT:C94694","NANDO:2200923","ICD9:279.49","UMLS:C0341305"],"synonyms":[{"name":"immune-mediated protracted diarrhea of infancy","type":"exact"},{"name":"immune-mediated protracted diarrhoea of infancy","type":"exact"},{"name":"severe immune-mediated enteropathy","type":"exact"}],"termid":"MONDO:0019787","xrefs":{"Monarch":{"xref_id":"0019787"}}}


id: PATO:0000914
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000914 continuant (obsolete PATO:0000914)","termid":"PATO:0000914"}


id: PBO:0038967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADNP homeobox 2","termid":"PBO:0038967"}


id: GO:1901010
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving (S)-reticuline.","definition_xrefs":["UniPathway:UPA00306","GOC:TermGenie","GOC:yaf"],"gene_count":0,"genotype_count":0,"name":"obsolete (S)-reticuline metabolic process (obsolete GO:1901010)","synonyms":[{"name":"(S)-reticuline metabolism","type":"exact"}],"termid":"GO:1901010"}


id: PBO:0058489
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5683","termid":"PBO:0058489"}


id: MONDO:0009412
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition that develops in people who do not consume an adequate amount of vitamin C in their diet. Although scurvy is relatively rare in the United States, it continues to be a problem in malnourished populations around the world (such as impoverished, underdeveloped third world countries). Early features of the condition include general weakness, fatigue and aching limbs. If left untreated, more serious problems can develop such as anemia, gum disease, and skin hemorrhages. Symptoms generally develop after at least 3 months of severe or total vitamin C deficiency. Scurvy can be cured with vitamin C supplements taken by mouth. Once recovery is complete, dietary modifications to ensure the 'recommended daily intake' of vitamin C is reached will prevent relapse. Except in the case of severe dental disease, permanent damage from scurvy does not usually occur.","direct_ancestors":[{"relation_name":"is_a","term_name":"vitamin deficiency disorder","termid":"MONDO:0024298"},{"relation_name":"is_a","term_name":"carbohydrate metabolism disease","termid":"MONDO:0037792"},{"relation_name":"is_a","term_name":"disorder of organic acid metabolism","termid":"MONDO:0045022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0037792"],"is_obsolete":false,"name":"scurvy","secondary_identifiers":["MESH:D001206","MESH:D012614","EFO:1001169","ICD10CM:E54","OMIM:240400","SCTID:76169001","DOID:13577","MedDRA:10039768","DOID:13724","icd11.foundation:708602629","MedDRA:10047623","MEDGEN:20684","ICD9:267","NCIT:C35010","UMLS:C0036474"],"synonyms":[{"name":"Gulo, nonfunctional","type":"related"},{"name":"L-gulonolactone oxidase pseudogene","type":"related"},{"name":"L-gulonolactone oxidase, nonfunctional","type":"related"},{"name":"ascorbic acid deficiency","type":"exact"},{"name":"deficiency of vitamin C","type":"exact"},{"name":"hypoascorbemia","type":"related"},{"name":"scorbutus","type":"related"},{"name":"scurvy","type":"exact"},{"name":"vitamin C deficiency","type":"exact"},{"name":"vitamin C, inability to synthesise","type":"related"},{"name":"vitamin C, inability to synthesize","type":"related"}],"termid":"MONDO:0009412","xrefs":{"Monarch":{"xref_id":"0009412"}}}


id: MONDO:0006210
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A distinctive type of liver cell carcinoma that arises in non-cirrhotic livers and is seen predominantly in young patients. The tumor cells are polygonal and deeply eosinophilic, and are embedded in a fibrous stroma. The prognosis is similar to classical hepatocellular carcinoma that arises in non-cirrhotic livers, and better than hepatocellular carcinoma that arises in cirrhotic livers.","definition_xrefs":["NCIT:C4131"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hepatocellular carcinoma","termid":"MONDO:0007256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"fibrolamellar hepatocellular carcinoma","secondary_identifiers":["DOID:5015","MEDGEN:83122","MESH:C537258","EFO:1000256","ONCOTREE:FLC","ICDO:8171/3","Orphanet:401920","GARD:21704","SCTID:253018005","UMLS:C0334287"],"synonyms":[{"name":"FHCC","type":"exact"},{"name":"FL-HCC","type":"related"},{"name":"FLC","type":"exact"},{"name":"eosinophilic glassy cell hepatoma","type":"related"},{"name":"eosinophilic hepatocellular carcinoma with lamellar fibrosis","type":"related"},{"name":"fibrolamellar cancer","type":"exact"},{"name":"fibrolamellar carcinoma","type":"exact"},{"name":"fibrolamellar carcinoma of liver cells","type":"exact"},{"name":"fibrolamellar carcinoma of the liver cells","type":"exact"},{"name":"fibrolamellar hepatocarcinoma","type":"exact"},{"name":"fibrolamellar hepatocellular carcinoma","type":"exact"},{"name":"fibrolamellar oncocytic hepatoma","type":"related"},{"name":"fibrolamellar variant of hepatocellular carcinoma","type":"related"},{"name":"hepatocellular carcinoma (fibrolamellar variant)","type":"related"},{"name":"hepatocellular carcinoma with increased stromal fibrosis","type":"related"},{"name":"hepatocellular carcinoma, fibrolamellar","type":"exact"},{"name":"hepatocellular fibrolamellar carcinoma","type":"exact"},{"name":"liver cell fibrolamellar carcinoma","type":"exact"},{"name":"oncocytic hepatocellular tumor","type":"exact"},{"name":"oncocytic hepatocellular tumour","type":"exact"},{"name":"polygonal cell hepatocellular carcinoma with fibrous stroma","type":"related"},{"name":"polygonal cell type hepatocellular carcinoma with fibrous Stroma","type":"exact"}],"termid":"MONDO:0006210","xrefs":{"Monarch":{"xref_id":"0006210"}}}


id: PBO:0091758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar copper exporter Ctr6","termid":"PBO:0091758"}


id: MONDO:0850461
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A fetal alcohol spectrum disorder that is characterized by one or more deficits in neurocognition and in self-regulation plus two or more deficits in adaptive functioning, with at least 1 in communication or social communication and interaction.","definition_xrefs":["DOID:0081052"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fetal alcohol spectrum disorder","termid":"MONDO:0000408"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurobehavioral disorder with prenatal alcohol exposure","termid":"MONDO:0850461","xrefs":{"Monarch":{"xref_id":"0850461"}}}


id: GO:0042445
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic process","termid":"GO:0008152"},{"relation_name":"is_a","term_name":"regulation of hormone levels","termid":"GO:0010817"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hormone metabolic process","secondary_identifiers":["GO:0034754"],"synonyms":[{"name":"cellular hormone metabolic process","type":"related"},{"name":"hormone metabolism","type":"exact"}],"termid":"GO:0042445"}


id: PR:Q9USM7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- tim23 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9USM7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial import inner membrane translocase subunit tim23 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC16A11.09c","synonyms":[{"name":"Spom972h-tim23","type":"exact"}],"termid":"PR:Q9USM7"}


id: PBO:0061780
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"OCIAD1 antisense RNA 1","termid":"PBO:0061780"}


id: MONDO:0006103
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A sporadic or familial pheochromocytoma that is confined to the adrenal gland and does not have any metastatic potential. The majority of cases are sporadic, and usually unilateral. Familial cases are usually bilateral.","definition_xrefs":["NCIT:C48305"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adrenal gland pheochromocytoma","termid":"MONDO:0004974"},{"relation_name":"is_a","term_name":"benign neoplasm of adrenal medulla","termid":"MONDO:0021468"},{"relation_name":"is_a","term_name":"benign epithelial neoplasm","termid":"MONDO:0036976"},{"relation_name":"is_a","term_name":"benign neoplasm of peripheral nervous system","termid":"MONDO:0056804"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign adrenal gland pheochromocytoma","secondary_identifiers":["EFO:1000106","MEDGEN:317403","UMLS:C1706920"],"synonyms":[{"name":"adrenal gland pheochromocytoma, benign","type":"exact"},{"name":"benign adrenal gland pheochromocytoma","type":"exact"},{"name":"pheochromocytoma, benign","type":"exact"}],"termid":"MONDO:0006103","xrefs":{"Monarch":{"xref_id":"0006103"}}}


id: PBO:0113529
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in vacuole; involved, along with functional homolog Prc1p, in vacuolar zymogen activation, breakdown of autophagic body, and autophagosome-dependent protein synthesis; role in phytochelatin synthesis; targeted to vacuole via Vps10p-dependent endosomal vacuolar protein sorting pathway; member of serine carboxypeptidase family; N-glycosylated","termid":"PBO:0113529"}


id: GO:1990328
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways.","definition_xrefs":["PMID:15591044","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein-containing complex","termid":"GO:0140535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"RPB4-RPB7 complex","synonyms":[{"name":"RNA polymerase II, RPB4-RPB7 subcomplex","type":"narrow"}],"termid":"GO:1990328"}


id: GO:1901862
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.","definition_xrefs":["PMID:23150719","GOC:TermGenie","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"regulation of muscle tissue development","termid":"GO:1901861"},{"relation_name":"negatively_regulates","term_name":"muscle tissue development","termid":"GO:0060537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of muscle tissue development","synonyms":[{"name":"down regulation of muscle tissue development","type":"exact"},{"name":"down-regulation of muscle tissue development","type":"exact"},{"name":"downregulation of muscle tissue development","type":"exact"},{"name":"inhibition of muscle tissue development","type":"narrow"}],"termid":"GO:1901862"}


id: PBO:0090547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cdc25 family phosphatase Ibp1, unknown role, implicated in DNA replication","termid":"PBO:0090547"}


id: FYPO:0002982
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of serine residues in one or more specific proteins, or of specific protein sites, does not occur.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete abolished protein serine phosphorylation during vegetative growth (obsolete FYPO:0002982)","synonyms":[{"name":"abolished peptidyl-serine phosphorylation during vegetative growth","type":"exact"},{"name":"abolished protein serine phosphorylation during mitotic cell cycle","type":"related"},{"name":"protein serine phosphorylation abolished during vegetative growth","type":"exact"}],"termid":"FYPO:0002982"}


id: MOD:01841
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links either two or an L-cysteine residue and an L-serine residue by a thioether bond to form a lanthionine, either D- or L- or meso-lanthionine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-carbon thioether crosslinked residues","termid":"MOD:01993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"lanthionine","synonyms":[{"name":"2,6-diamino-4-thiaheptanedioic acid","type":"exact"},{"name":"2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid","type":"exact"},{"name":"3,3'-thiobis-(2-aminopropanoic acid)","type":"exact"},{"name":"3,3'-thiobis-L-alanine","type":"exact"},{"name":"S-(2-amino-2-carboxyethyl)-L-cysteine","type":"exact"},{"name":"bis(2-amino-2-carboxyethyl)sulfanediyl","type":"exact"},{"name":"bis(2-amino-2-carboxyethyl)sulfide","type":"exact"}],"termid":"MOD:01841"}


id: GO:1990054
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.","definition_xrefs":["GOC:hp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to temozolomide","termid":"GO:1990054"}


id: GO:0102282
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: NAD(1-) + a sphinganine = 3-dehydrosphinganinium(1+) + NADH + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 3-ketodihydrosphinganine (C18) reductase activity (obsolete GO:0102282)","termid":"GO:0102282"}


id: MONDO:0009957
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Reese retinal dysplasia","secondary_identifiers":["MEDGEN:341456","OMIM:266400","UMLS:C1849450","MESH:C564854"],"synonyms":[{"name":"Reese retinal dysplasia","type":"exact"}],"termid":"MONDO:0009957","xrefs":{"Monarch":{"xref_id":"0009957"}}}


id: PR:P05933
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A calmodulin that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00584","PRO:DNx","PANTHER:PTHR23050:SF20"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calmodulin (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3A12.14","secondary_identifiers":["UniProtKB:P05933"],"synonyms":[{"name":"CaM (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-CALM","type":"exact"}],"termid":"PR:P05933"}


id: PBO:0077530
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 243","termid":"PBO:0077530"}


id: GO:0032205
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of telomere maintenance","termid":"GO:0032204"},{"relation_name":"is_a","term_name":"negative regulation of DNA metabolic process","termid":"GO:0051053"},{"relation_name":"is_a","term_name":"negative regulation of chromosome organization","termid":"GO:2001251"},{"relation_name":"negatively_regulates","term_name":"telomere maintenance","termid":"GO:0000723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0032200"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"negatively_regulates","termid":"GO:0032200"}],"interesting_parent_ids":["GO:0008150","GO:0032200","GO:0006259"],"is_obsolete":false,"name":"negative regulation of telomere maintenance","synonyms":[{"name":"down regulation of telomere maintenance","type":"exact"},{"name":"down-regulation of telomere maintenance","type":"exact"},{"name":"downregulation of telomere maintenance","type":"exact"},{"name":"inhibition of telomere maintenance","type":"narrow"}],"termid":"GO:0032205"}


id: GO:0070035
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete purine NTP-dependent helicase activity (obsolete GO:0070035)","termid":"GO:0070035"}


id: GO:0061066
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.","definition_xrefs":["GOC:kmv","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of nematode larval development","termid":"GO:0061063"},{"relation_name":"is_a","term_name":"regulation of dauer larval development","termid":"GO:0061065"},{"relation_name":"positively_regulates","term_name":"dauer larval development","termid":"GO:0040024"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of dauer larval development","termid":"GO:0061066"}


id: FYPO:0005850
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions does not occur.","definition_xrefs":["PMID:27648579","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to pericentric heterochromatin during vegetative growth","termid":"FYPO:0003074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"abolished protein localization to heterochromatin at centromere outer repeat","synonyms":[{"name":"abolished protein localisation to chromatin at centromere outer repeat","type":"exact"},{"name":"abolished protein localisation to heterochromatin at centromere outer repeat","type":"exact"},{"name":"abolished protein localization at centromere otr","type":"exact"},{"name":"abolished protein localization at centromeric outer repeat region","type":"exact"},{"name":"abolished protein localization at pericentric region","type":"related"},{"name":"abolished protein localization at pericentromeric region","type":"related"},{"name":"abolished protein localization to centromere outer repeat heterochromatin","type":"exact"},{"name":"abolished protein localization to chromatin at centromere otr","type":"exact"},{"name":"abolished protein localization to chromatin at centromere outer repeat","type":"exact"},{"name":"abolished protein localization to chromatin at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to chromatin at centromere outer repeat during vegetative growth","type":"exact"},{"name":"abolished protein localization to chromatin at centromeric outer repeat","type":"exact"},{"name":"abolished protein localization to chromatin at pericentric region","type":"related"},{"name":"abolished protein localization to chromatin at pericentromeric region","type":"related"},{"name":"abolished protein localization to heterochromatin at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to heterochromatin at centromere outer repeat during vegetative growth","type":"exact"},{"name":"protein localization to heterochromatin at centromere outer repeat abolished","type":"exact"}],"termid":"FYPO:0005850"}


id: PR:P40902
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- isp7 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P40902"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sexual differentiation process protein isp7 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC25B8.13c","synonyms":[{"name":"Spom972h-isp7","type":"exact"}],"termid":"PR:P40902"}


id: MONDO:0007951
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"masticatory muscles, hypertrophy of","secondary_identifiers":["MESH:C563600","OMIM:154850","MEDGEN:322570","SCTID:699649006","UMLS:C1835093"],"synonyms":[{"name":"masseter muscle Hypertrophy","type":"related"},{"name":"masticatory muscles, hypertrophy of","type":"exact"}],"termid":"MONDO:0007951","xrefs":{"Monarch":{"xref_id":"0007951"}}}


id: GO:0031613
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteasome regulatory particle, lid subcomplex","termid":"GO:0008541"},{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"},{"relation_name":"part_of","term_name":"nuclear proteasome regulatory particle","termid":"GO:0031598"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005634"],"is_obsolete":false,"name":"nuclear proteasome regulatory particle, lid subcomplex","termid":"GO:0031613"}


id: MONDO:0014706
data:
  {"annotated_genes":["SJAG_00660","SJAG_03457"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85769,85770],"is_not":false,"summary":null,"term":"MONDO:0014706"}]},"cv_name":"mondo","definition":"An autosomal dominant cutis laxa characterized by thin skin with visible veins and wrinkles, cataract or corneal clouding, clenched fingers, pre- and postnatal growth retardation, moderate intellectual disability, and a combination of muscle hypotonia with brisk muscle reflexes that has material basis in heterozygous mutation in the ALDH18A1 gene on chromosome 10q24.","definition_xrefs":["DOID:0070131"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"autosomal dominant cutis laxa","termid":"MONDO:0019571"},{"relation_name":"is_a","term_name":"P5CS deficiency","termid":"MONDO:0100126"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00660":null,"SJAG_03457":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736","MONDO:0000426","MONDO:0005328"],"is_obsolete":false,"name":"cutis laxa, autosomal dominant 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16143","OMIM:616603","MEDGEN:899774","UMLS:C4225268"],"synonyms":[{"name":"ADCL3","type":"exact"},{"name":"autosomal dominant cutis laxa 3","type":"related"},{"name":"cutis laxa, autosomal dominant 3","type":"exact"},{"name":"cutis laxa, autosomal dominant type 3","type":"exact"}],"termid":"MONDO:0014706","terms_by_termid":{"MONDO:0014706":null},"xrefs":{"Monarch":{"xref_id":"0014706"}}}


id: PBO:0073240
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"selenophosphate synthetase 1 pseudogene 4","termid":"PBO:0073240"}


id: MONDO:0024388
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with bacteria of the genus clostridium.","definition_xrefs":["MESH:D003015"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gram-positive bacterial infections","termid":"MONDO:0021679"},{"relation_name":"is_a","term_name":"anaerobic bacteria infectious disease","termid":"MONDO:0024389"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clostridium infectious disease","secondary_identifiers":["SCTID:56688005","EFO:1000874","ICD9:040.89"],"synonyms":[{"name":"Clostridium infection","type":"related"},{"name":"commensal Clostridium infection","type":"related"},{"name":"commensal infection, Clostridium","type":"related"},{"name":"commensal infections, Clostridium","type":"related"},{"name":"infection, Clostridium","type":"related"},{"name":"infections, Clostridium","type":"related"}],"termid":"MONDO:0024388","xrefs":{"Monarch":{"xref_id":"0024388"}}}


id: PBO:0109141
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cryptic, EGF-CFC family member 1","termid":"PBO:0109141"}


id: PBO:0073219
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SEMA6A antisense RNA 1","termid":"PBO:0073219"}


id: PBO:0049158
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRAM domain containing 4","termid":"PBO:0049158"}


id: GO:0007338
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The union of male and female gametes to form a zygote.","definition_xrefs":["GOC:ems","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fertilization","termid":"GO:0009566"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"single fertilization","secondary_identifiers":["Reactome:R-HSA-1187000"],"synonyms":[{"name":"zygote biosynthesis","type":"related"},{"name":"zygote formation","type":"related"}],"termid":"GO:0007338"}


id: PBO:0003295
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AP-1 adaptor complex subunit beta subunit Apl2","termid":"PBO:0003295"}


id: GO:0015074
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA metabolic process","termid":"GO:0006259"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006259"],"is_obsolete":false,"name":"DNA integration","termid":"GO:0015074"}


id: GO:0033380
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protease localization to T cell secretory granule","termid":"GO:0033375"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"granzyme B localization to T cell secretory granule","synonyms":[{"name":"granzyme B localisation in T cell secretory granule","type":"exact"},{"name":"granzyme B localization in T cell secretory granule","type":"exact"},{"name":"granzyme B localization in T lymphocyte secretory granule","type":"exact"},{"name":"granzyme B localization in T-cell secretory granule","type":"exact"},{"name":"granzyme B localization in T-lymphocyte secretory granule","type":"exact"}],"termid":"GO:0033380"}


id: PBO:0088411
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pentafunctional aromatic polypeptide Aro1","termid":"PBO:0088411"}


id: GO:1900159
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation.","definition_xrefs":["GOC:TermGenie","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of bone mineralization","termid":"GO:0030501"},{"relation_name":"is_a","term_name":"regulation of bone mineralization involved in bone maturation","termid":"GO:1900157"},{"relation_name":"positively_regulates","term_name":"bone mineralization involved in bone maturation","termid":"GO:0035630"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of bone mineralization involved in bone maturation","synonyms":[{"name":"activation of bone mineralization involved in bone maturation","type":"narrow"},{"name":"up regulation of bone mineralization involved in bone maturation","type":"exact"},{"name":"up-regulation of bone mineralization involved in bone maturation","type":"exact"},{"name":"upregulation of bone mineralization involved in bone maturation","type":"exact"}],"termid":"GO:1900159"}


id: GO:0015548
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom.","definition_xrefs":["PMID:18793329","GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete organomercurial transmembrane transporter activity (obsolete GO:0015548)","synonyms":[{"name":"carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity","type":"narrow"},{"name":"organomercurial transporter activity","type":"related"}],"termid":"GO:0015548"}


id: PBO:0000049
data:
  {"annotation_feature_type":"gene","cv_name":"feature_cvtermprop_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"qualifier","termid":"PBO:0000049"}


id: PBO:0084683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58","termid":"PBO:0084683"}


id: MONDO:0017968
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"46,XY ovotesticular disorder of sex development is a rare, genetic disorder of sex development characterized by either the coexistence of both male and female reproductive gonads or, more frequently, by the presence of one or both gonads containing a mixture of both testicular and ovarian tissue (ovotestes) in an individual with a normal male 46, XY karyotype. External genitalia are usually ambiguous, but can range from normal male to normal female and if a uterus and/or fallopian tubes are present, they are generally hypoplastic. Cryptorchidism, hypospadias, infertility and increased risk of gonadal tumors are frequently associated.","definition_xrefs":["Orphanet:325345"],"direct_ancestors":[{"relation_name":"is_a","term_name":"46,XY disorder of sex development","termid":"MONDO:0020040"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"46,XY ovotesticular disorder of sex development","secondary_identifiers":["GARD:21469","UMLS:C2697358","MEDGEN:394582","SCTID:763683004"],"synonyms":[{"name":"46,XY ovotesticular DSD","type":"exact"}],"termid":"MONDO:0017968","xrefs":{"Monarch":{"xref_id":"0017968"}}}


id: PBO:0064351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plexin C1","termid":"PBO:0064351"}


id: PBO:0034217
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-is_concretized_as","termid":"PBO:0034217"}


id: SO:0000925
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An edit to insert a GU dinucleotide.","definition_xrefs":["SO:ke"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000925 insert_GU (obsolete SO:0000925)","synonyms":[{"name":"insert GU","type":"exact"}],"termid":"SO:0000925"}


id: MONDO:0016231
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"vascular disorder","termid":"MONDO:0005385"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"capillary malformation","secondary_identifiers":["SCTID:234118009","UMLS:C0340803","MEDGEN:90955","Orphanet:211247"],"synonyms":[{"name":"congenital malformation of capillary","type":"narrow"},{"name":"rare capillary malformation","type":"related"}],"termid":"MONDO:0016231","xrefs":{"Monarch":{"xref_id":"0016231"}}}


id: GO:1905603
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.","definition_xrefs":["PMID:30280653","GOC:als","PMID:22524708","GO_REF:0000058","GOC:aruk","GOC:bc","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of vascular permeability","termid":"GO:0043114"},{"relation_name":"part_of","term_name":"maintenance of blood-brain barrier","termid":"GO:0035633"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of blood-brain barrier permeability","synonyms":[{"name":"regulation of BBB permeability","type":"exact"},{"name":"regulation of blood/brain barrier permeability","type":"exact"}],"termid":"GO:1905603"}


id: GO:0010971
data:
  {"annotated_genes":["SJAG_01901","SJAG_04486","SJAG_01000","SJAG_00256","SJAG_01456","SJAG_00214","SJAG_03592","SJAG_03309","SJAG_01805","SJAG_04332","SJAG_00216","SJAG_02342","SJAG_02592","SJAG_00883","SJAG_03067","SJAG_00117","SJAG_03602","SJAG_04140","SJAG_03486","SJAG_04597","SJAG_01837"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70683,73333,87809,87818,91497,91901,93565,94131,94170,98186,98759,101511,103244,106990,108329,110094,110950,116227,116415],"is_not":false,"summary":null,"term":"GO:0010971"},{"annotations":[101142,87612],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905287"}]},"cv_name":"biological_process","definition":"Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.","definition_xrefs":["GOC:tb","GOC:dph","GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of G2/M transition of mitotic cell cycle","termid":"GO:0010389"},{"relation_name":"is_a","term_name":"positive regulation of mitotic cell cycle phase transition","termid":"GO:1901992"},{"relation_name":"is_a","term_name":"positive regulation of cell cycle G2/M phase transition","termid":"GO:1902751"},{"relation_name":"positively_regulates","term_name":"G2/M transition of mitotic cell cycle","termid":"GO:0000086"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00117":null,"SJAG_00214":null,"SJAG_00216":null,"SJAG_00256":null,"SJAG_00883":null,"SJAG_01000":null,"SJAG_01456":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_01901":null,"SJAG_02342":null,"SJAG_02592":null,"SJAG_03067":null,"SJAG_03309":null,"SJAG_03486":null,"SJAG_03592":null,"SJAG_03602":null,"SJAG_04140":null,"SJAG_04332":null,"SJAG_04486":null,"SJAG_04597":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0044772"},{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044772"}],"interesting_parent_ids":["GO:0008150","GO:0044772","GO:0007049"],"is_obsolete":false,"name":"positive regulation of G2/M transition of mitotic cell cycle","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0031662"],"synonyms":[{"name":"positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle","type":"related"},{"name":"positive regulation of mitotic entry","type":"exact"}],"termid":"GO:0010971","terms_by_termid":{"GO:0010971":null,"GO:1905287":null}}


id: MONDO:0022908
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cutis gyratum acanthosis nigricans craniosynostosis","termid":"MONDO:0022908","xrefs":{"Monarch":{"xref_id":"0022908"}}}


id: GO:1901682
data:
  {"annotated_genes":["SJAG_03577","SJAG_01660","SJAG_04295","SJAG_01941","SJAG_04673","SJAG_00671","SJAG_00835","SJAG_02463","SJAG_01589","SJAG_01890","SJAG_02779","SJAG_02780","SJAG_04325","SJAG_02962","SJAG_03334","SJAG_03452","SJAG_03652"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[101115],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046964"},{"annotations":[101116],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902557"},{"annotations":[59578],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008521"},{"annotations":[79057,71597],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015225"},{"annotations":[70280],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015228"},{"annotations":[75103],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033229"},{"annotations":[95283,112879],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034634"},{"annotations":[100436],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034216"},{"annotations":[79860,75823],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000095"},{"annotations":[65517],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008271"},{"annotations":[73652,88177],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015116"},{"annotations":[103391],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090422"},{"annotations":[89916,89915],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015234"},{"annotations":[88178],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015117"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a sulfur compound from one side of a membrane to the other.","definition_xrefs":["GOC:TermGenie","GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane transporter activity","termid":"GO:0022857"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00671":null,"SJAG_00835":null,"SJAG_01589":null,"SJAG_01660":null,"SJAG_01890":null,"SJAG_01941":null,"SJAG_02463":null,"SJAG_02779":null,"SJAG_02780":null,"SJAG_02962":null,"SJAG_03334":null,"SJAG_03452":null,"SJAG_03577":null,"SJAG_03652":null,"SJAG_04295":null,"SJAG_04325":null,"SJAG_04673":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"sulfur compound transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"sulfur molecular entity transmembrane transporter activity","type":"exact"}],"termid":"GO:1901682","terms_by_termid":{"GO:0000095":null,"GO:0008271":null,"GO:0008521":null,"GO:0015116":null,"GO:0015117":null,"GO:0015225":null,"GO:0015228":null,"GO:0015234":null,"GO:0033229":null,"GO:0034216":null,"GO:0034634":null,"GO:0046964":null,"GO:0090422":null,"GO:1902557":null}}


id: MONDO:0014854
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the CD164 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0019497"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0019497"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 66","secondary_identifiers":["GARD:18146","UMLS:C4283893","DOID:0110587","OMIM:616969","MEDGEN:924418"],"synonyms":[{"name":"CD164 autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"DFNA66","type":"narrow"},{"name":"autosomal dominant deafness 66","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 66","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in CD164","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 66","type":"narrow"},{"name":"deafness, autosomal dominant 66","type":"narrow"},{"name":"deafness, autosomal dominant type 66","type":"narrow"}],"termid":"MONDO:0014854","xrefs":{"Monarch":{"xref_id":"0014854"}}}


id: MONDO:0011707
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete familial dyskinesia and facial myokymia (obsolete MONDO:0011707)","termid":"MONDO:0011707","xrefs":{"Monarch":{"xref_id":"0011707"}}}


id: MONDO:1010270
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Alkaptonuria that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn errors of metabolism, non-human animal","termid":"MONDO:1012979"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alkaptonuria, non-human animal","secondary_identifiers":["OMIA:001243"],"termid":"MONDO:1010270","xrefs":{"Monarch":{"xref_id":"1010270"}}}


id: FYPO:0001578
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing a dipeptide such as Leu-Ala as the nitrogen source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0002057","FYPO:0000003","FYPO:0002060","FYPO:0002058","FYPO:0000257"],"is_obsolete":false,"name":"normal growth on dipeptide nitrogen source","synonyms":[{"name":"normal cell population growth on dipeptide nitrogen source","type":"exact"},{"name":"normal dipeptide utilization","type":"related"},{"name":"normal vegetative cell population growth on dipeptide nitrogen source","type":"exact"}],"termid":"FYPO:0001578"}


id: PBO:0047223
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 227 member A","termid":"PBO:0047223"}


id: PATO:0000962
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000962 absolute opacity value (obsolete PATO:0000962)","termid":"PATO:0000962"}


id: PBO:0059292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein L43","termid":"PBO:0059292"}


id: PBO:0046629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group W member 10","termid":"PBO:0046629"}


id: PBO:0042067
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 137","termid":"PBO:0042067"}


id: MONDO:0005772
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infection due to the fungus Geotrichum.","definition_xrefs":["MESH:D005847"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"immune system disorder","termid":"MONDO:0005046"},{"relation_name":"is_a","term_name":"opportunistic mycosis","termid":"MONDO:0002312"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"geotrichosis","secondary_identifiers":["DOID:2832","icd11.foundation:1432903072","SCTID:13969006","ICD9:117.9","ICD10CM:B48.3","UMLS:C0017455","MEDGEN:42202"],"termid":"MONDO:0005772","xrefs":{"Monarch":{"xref_id":"0005772"}}}


id: GO:0150151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of interleukin-17A production.","definition_xrefs":["PMID:27901018","GOC:aruk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of interleukin-17 production","termid":"GO:0032660"},{"relation_name":"regulates","term_name":"interleukin-17A production","termid":"GO:0097087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of interleukin-17A production","synonyms":[{"name":"regulation of interleukin-17A biosynthetic process","type":"narrow"}],"termid":"GO:0150151"}


id: FYPO:0002043
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which premeiotic DNA replication is normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal DNA replication","termid":"FYPO:0001133"},{"relation_name":"is_a","term_name":"normal meiotic cell cycle process","termid":"FYPO:0007078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal premeiotic DNA replication","synonyms":[{"name":"abnormal premeiotic DNA synthesis","type":"related"},{"name":"normal meiotic DNA replication","type":"related"},{"name":"normal meiotic DNA synthesis","type":"related"}],"termid":"FYPO:0002043"}


id: GO:0006833
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fluid transport","termid":"GO:0042044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"water transport","secondary_identifiers":["Reactome:R-HSA-445717"],"termid":"GO:0006833"}


id: GO:0046627
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"regulation of insulin receptor signaling pathway","termid":"GO:0046626"},{"relation_name":"is_a","term_name":"negative regulation of cellular response to insulin stimulus","termid":"GO:1900077"},{"relation_name":"negatively_regulates","term_name":"insulin receptor signaling pathway","termid":"GO:0008286"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of insulin receptor signaling pathway","synonyms":[{"name":"down regulation of insulin receptor signaling pathway","type":"exact"},{"name":"down-regulation of insulin receptor signaling pathway","type":"exact"},{"name":"downregulation of insulin receptor signaling pathway","type":"exact"},{"name":"inhibition of insulin receptor signaling pathway","type":"narrow"},{"name":"negative regulation of insulin receptor signalling pathway","type":"exact"}],"termid":"GO:0046627"}


id: PBO:0064527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase III subunit G","termid":"PBO:0064527"}


id: MONDO:0005048
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An insulin-producing neuroendocrine tumor arising from the beta cells of the pancreas. It may or may not be associated with inappropriate secretion of insulin and an associated clinical syndrome.","definition_xrefs":["NCIT:C3140"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreatic neuroendocrine tumor","termid":"MONDO:0019954"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"pancreatic insulin-producing neuroendocrine tumor","secondary_identifiers":["ICDO:8151/0","EFO:0000549","MEDGEN:1844884","Orphanet:97279","GARD:3010","ICDO:8151/1","UMLS:C5848150"],"synonyms":[{"name":"Beta cell tumor","type":"exact"},{"name":"Beta cell tumor of pancreas","type":"exact"},{"name":"Beta cell tumor of the pancreas","type":"exact"},{"name":"Beta cell tumour","type":"exact"},{"name":"Beta cell tumour of pancreas","type":"exact"},{"name":"Beta cell tumour of the pancreas","type":"exact"},{"name":"beta cell neoplasm","type":"exact"},{"name":"beta cell tumor of the pancreas","type":"exact"},{"name":"beta cell tumour of the pancreas","type":"exact"},{"name":"insulin-producing islet cell tumor","type":"exact"},{"name":"insulin-producing islet cell tumour","type":"exact"},{"name":"insulin-producing tumor of islet cells","type":"exact"},{"name":"insulin-producing tumor of the islet cells","type":"exact"},{"name":"insulin-producing tumour of islet cells","type":"exact"},{"name":"insulin-producing tumour of the islet cells","type":"exact"},{"name":"pancreatic Beta cell tumor","type":"exact"},{"name":"pancreatic Beta cell tumour","type":"exact"},{"name":"pancreatic insulin producing NET","type":"exact"},{"name":"pancreatic insulin producing neoplasm","type":"exact"},{"name":"pancreatic insulin producing tumor","type":"exact"},{"name":"pancreatic insulin producing tumour","type":"exact"},{"name":"pancreatic insulin-producing neuroendocrine tumor","type":"exact"},{"name":"pancreatic insulin-producing tumor","type":"exact"},{"name":"pancreatic insulin-producing tumour","type":"exact"}],"termid":"MONDO:0005048","xrefs":{"Monarch":{"xref_id":"0005048"}}}


id: GO:0090103
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the cochlea is generated and organized.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"embryonic morphogenesis","termid":"GO:0048598"},{"relation_name":"part_of","term_name":"inner ear morphogenesis","termid":"GO:0042472"},{"relation_name":"part_of","term_name":"cochlea development","termid":"GO:0090102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cochlea morphogenesis","termid":"GO:0090103"}


id: GO:0002409
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The movement of a Langerhans cell in response to an external stimulus.","definition_xrefs":["GOC:add","PMID:16056255","PMID:16387601"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid dendritic cell chemotaxis","termid":"GO:0002408"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"Langerhans cell chemotaxis","termid":"GO:0002409"}


id: PBO:0027721
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_deacetylation","termid":"PBO:0027721"}


id: MONDO:0002120
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma.","definition_xrefs":["NCIT:C3773"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carcinoma","termid":"MONDO:0004993"},{"relation_name":"is_a","term_name":"neuroendocrine neoplasm","termid":"MONDO:0019496"},{"relation_name":"is_a","term_name":"malignant endocrine neoplasm","termid":"MONDO:0021069"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"neuroendocrine carcinoma","secondary_identifiers":["MEDGEN:104919","MESH:D018278","SCTID:253000007","DOID:1800","ICDO:8246/3","UMLS:C0206695"],"synonyms":[{"name":"NEC","type":"exact"},{"name":"neuroendocrine cancer","type":"exact"},{"name":"neuroendocrine carcinoma","type":"exact"}],"termid":"MONDO:0002120","xrefs":{"Monarch":{"xref_id":"0002120"}}}


id: MONDO:0013367
data:
  {"annotated_genes":["SJAG_03764"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87128],"is_not":false,"summary":null,"term":"MONDO:0013367"}]},"cv_name":"mondo","definition":"An autosomal dominant condition caused by mutation(s) in the KCNH2 gene, encoding potassium voltage-gated channel subfamily H member 2. It is characterized by a prolonged QT interval that may result in torsade de pointes, ventricular fibrillation and/or sudden cardiac death.","definition_xrefs":["NCIT:C137957"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"long QT syndrome","termid":"MONDO:0002442"},{"relation_name":"is_a","term_name":"familial long QT syndrome","termid":"MONDO:0019171"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03764":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"long QT syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:462293","OMIM:613688","GARD:3285","DOID:0110645","MESH:C563614","UMLS:C3150943","HGNC:6251"],"synonyms":[{"name":"LQT2","type":"exact"},{"name":"Long QT syndrome, acquired, reduced susceptibility to","type":"exact"},{"name":"long QT syndrome 1/2, digenic","type":"related"},{"name":"long QT syndrome 2","type":"exact"},{"name":"long QT syndrome 2, acquired, susceptibility to","type":"related"},{"name":"long QT syndrome 2/3, digenic","type":"related"},{"name":"long QT syndrome 2/5, digenic","type":"related"},{"name":"long QT syndrome 2/9, digenic","type":"related"},{"name":"long QT syndrome type 2","type":"exact"}],"termid":"MONDO:0013367","terms_by_termid":{"MONDO:0013367":null},"xrefs":{"Monarch":{"xref_id":"0013367"}}}


id: GO:0052406
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete metabolism by host of symbiont carbohydrate (obsolete GO:0052406)","termid":"GO:0052406"}


id: MONDO:0009502
data:
  {"annotated_genes":["SJAG_02158"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86546],"is_not":false,"summary":null,"term":"MONDO:0009502"}]},"cv_name":"mondo","definition":"Pyruvate dehydrogenase E2 deficiency is a very rare form of pyruvate dehydrogenase deficiency (PDHD) characterized by variable lactic acidosis and neurological dysfunction, mainly appearing during childhood.","definition_xrefs":["Orphanet:79244"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyruvate dehydrogenase deficiency","termid":"MONDO:0019169"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02158":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005244","MONDO:0005066","MONDO:0037792"],"is_obsolete":false,"name":"pyruvate dehydrogenase E2 deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1855565","OMIM:245348","MEDGEN:343386","GARD:16712","MESH:C565448"],"synonyms":[{"name":"PDHDD","type":"related"},{"name":"dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex deficiency","type":"exact"},{"name":"dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex deficiency","type":"exact"},{"name":"lactic acidemia due to defect of E2 lipoyl transacetylase of the pyruvate dehydrogenase Complex","type":"related"},{"name":"pyruvate dehydrogenase E2 deficiency","type":"exact"},{"name":"pyruvate dehydrogenase complex component E2 deficiency","type":"exact"}],"termid":"MONDO:0009502","terms_by_termid":{"MONDO:0009502":null},"xrefs":{"Monarch":{"xref_id":"0009502"}}}


id: PBO:0075860
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SSX family member 8, pseudogene","termid":"PBO:0075860"}


id: GO:0102730
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor = teasterone + H2O + an oxidized electron acceptor.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete cathasterone hydroxylase activity (obsolete GO:0102730)","termid":"GO:0102730"}


id: PR:O13772
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC17A5.10 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13772"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline/serine-rich protein C17A5.10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17A5.10","synonyms":[{"name":"Spom972h-SPAC17A5.10","type":"exact"}],"termid":"PR:O13772"}


id: GO:2001164
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.","definition_xrefs":["PMID:15149594"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues (obsolete GO:2001164)","termid":"GO:2001164"}


id: GO:0046022
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle (obsolete GO:0046022)","synonyms":[{"name":"activation of transcription from RNA polymerase II promoter during mitosis","type":"narrow"},{"name":"mitotic activation of transcription from Pol II promoter","type":"exact"},{"name":"positive regulation of transcription from Pol II promoter during mitosis","type":"exact"},{"name":"positive regulation of transcription from RNA polymerase II promoter, mitotic","type":"exact"},{"name":"stimulation of transcription from RNA polymerase II promoter during mitosis","type":"narrow"},{"name":"up regulation of transcription from RNA polymerase II promoter during mitosis","type":"exact"},{"name":"up-regulation of transcription from RNA polymerase II promoter during mitosis","type":"exact"},{"name":"upregulation of transcription from RNA polymerase II promoter during mitosis","type":"exact"}],"termid":"GO:0046022"}


id: GO:1903006
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination.","definition_xrefs":["GO_REF:0000058","GOC:PARL","PMID:22970133","GOC:bf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein deubiquitination","termid":"GO:1903003"},{"relation_name":"is_a","term_name":"regulation of protein K63-linked deubiquitination","termid":"GO:1903004"},{"relation_name":"positively_regulates","term_name":"protein K63-linked deubiquitination","termid":"GO:0070536"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0070647"},{"rel_name":"positively_regulates","termid":"GO:0070647"}],"interesting_parent_ids":["GO:0008150","GO:0070647"],"is_obsolete":false,"name":"positive regulation of protein K63-linked deubiquitination","synonyms":[{"name":"activation of protein K63-linked deubiquitination","type":"narrow"},{"name":"up regulation of protein K63-linked deubiquitination","type":"exact"},{"name":"up-regulation of protein K63-linked deubiquitination","type":"exact"},{"name":"upregulation of protein K63-linked deubiquitination","type":"exact"}],"termid":"GO:1903006"}


id: GO:0004437
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.","definition_xrefs":["GOC:hb"],"gene_count":0,"genotype_count":0,"name":"obsolete inositol or phosphatidylinositol phosphatase activity (obsolete GO:0004437)","synonyms":[{"name":"inositol or phosphatidylinositol phosphatase activity","type":"exact"},{"name":"inositol/phosphatidylinositol phosphatase activity","type":"exact"}],"termid":"GO:0004437"}


id: GO:0043818
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H+ + NADH + O2 + precorrin-3A = H2O + NAD+ + precorrin-3B.","definition_xrefs":["EC:1.14.13.83","RHEA:17293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"precorrin-3B synthase activity","secondary_identifiers":["MetaCyc:R321-RXN","KEGG_REACTION:R05217"],"synonyms":[{"name":"CobG","type":"related"},{"name":"precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)","type":"exact"},{"name":"precorrin-3X synthase activity","type":"related"}],"termid":"GO:0043818"}


id: MONDO:0016959
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of chromosome 8","termid":"MONDO:0016929"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial duplication of the long arm of chromosome 8","secondary_identifiers":["UMLS:C5679703","icd11.foundation:397762525","Orphanet:262896","GARD:20879","MEDGEN:1826035"],"synonyms":[{"name":"partial duplication of chromosome 8q","type":"exact"},{"name":"partial duplication of the long arm of chromosome type 8","type":"exact"},{"name":"partial trisomy of chromosome 8q","type":"exact"},{"name":"partial trisomy of the long arm of chromosome 8","type":"exact"}],"termid":"MONDO:0016959","xrefs":{"Monarch":{"xref_id":"0016959"}}}


id: GO:0048100
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.","definition_xrefs":["GOC:jid","PMID:10625531"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anterior/posterior pattern specification, imaginal disc","termid":"GO:0007448"},{"relation_name":"is_a","term_name":"wing disc pattern formation","termid":"GO:0035222"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"wing disc anterior/posterior pattern formation","termid":"GO:0048100"}


id: MONDO:0005283
data:
  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id: PBO:0049689
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heart and neural crest derivatives expressed 2","termid":"PBO:0049689"}


id: PBO:0002338
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA-binding protein Rsd1 (predicted)","termid":"PBO:0002338"}


id: GO:1903698
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id: PBO:0000992
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  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tf2-type transposon","termid":"PBO:0000992"}


id: GO:0000210
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  {"annotated_genes":["SJAG_03091"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[59936],"is_not":false,"summary":null,"term":"GO:0000210"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: NAD+ + H2O = AMP + NMN.","definition_xrefs":["RHEA:11800"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dinucleotide phosphatase activity","termid":"GO:0004551"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03091":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824"],"is_obsolete":false,"name":"NAD+ diphosphatase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["MetaCyc:NADPYROPHOSPHAT-RXN"],"synonyms":[{"name":"NAD diphosphatase activity","type":"broad"},{"name":"NAD pyrophosphatase activity","type":"broad"},{"name":"NAD(+) pyrophosphatase activity","type":"exact"},{"name":"NAD+ phosphohydrolase activity","type":"exact"},{"name":"NAD+ pyrophosphatase activity","type":"exact"},{"name":"NADP pyrophosphatase activity","type":"related"},{"name":"nicotinamide adenine dinucleotide pyrophosphatase activity","type":"related"}],"termid":"GO:0000210","terms_by_termid":{"GO:0000210":null}}


id: PBO:0047688
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fms related receptor tyrosine kinase 1","termid":"PBO:0047688"}


id: PR:Q9UQY2
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  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A proteasome subunit beta type-1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11599:SF8","OMA:SCHPO01989","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome subunit beta type-6 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22F8.06","secondary_identifiers":["UniProtKB:Q9UQY2"],"synonyms":[{"name":"Spom972h-PSMB1","type":"exact"}],"termid":"PR:Q9UQY2"}


id: PBO:0061260
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"notch 2 N-terminal like C","termid":"PBO:0061260"}


id: PATO:0001460
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  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A sensitivity of a process inhering in a biological process by virtue of the process unfolding in a location without oxygen.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitivity of a process to oxygen","termid":"PATO:0001458"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaerobic (for occurrence)","termid":"PATO:0001460"}


id: GO:0071965
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"locomotion","termid":"GO:0040011"},{"relation_name":"is_a","term_name":"multicellular organismal movement","termid":"GO:0050879"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"multicellular organismal locomotion","termid":"GO:0071965"}


id: GO:0015043
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  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 Fe(III)-[leghemoglobin] + NAD(P)H = 2 Fe(II)-[leghemoglobin] + NAD(P)+ + H+.","definition_xrefs":["EC:1.6.2.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor","termid":"GO:0016653"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"leghemoglobin reductase [NAD(P)H] activity","secondary_identifiers":["MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN"],"synonyms":[{"name":"NAD(P)H:ferrileghemoglobin oxidoreductase activity","type":"related"},{"name":"ferric leghemoglobin reductase activity","type":"related"},{"name":"leghemoglobin reductase activity","type":"exact"}],"termid":"GO:0015043"}


id: FYPO:0000697
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  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA N-glycosylase activity","termid":"FYPO:0008216"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000707","FYPO:0000652","FYPO:0000661","FYPO:0001985"],"is_obsolete":false,"name":"abnormal DNA-7-methylguanine glycosylase activity","termid":"FYPO:0000697"}


id: PBO:0086384
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52p foci","termid":"PBO:0086384"}


id: PBO:0077664
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TNF receptor superfamily member 11a","termid":"PBO:0077664"}


id: PBO:0088288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab-specific(Ryh1/Ypt6) Ric1-Rgp1 guanyl-nucleotide exchange factor subunit Ric1/Sat4","termid":"PBO:0088288"}


id: PR:O59764
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  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ER membrane protein complex subunit 6 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04440","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER membrane protein complex subunit 6 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1020.11c","secondary_identifiers":["UniProtKB:O59764"],"synonyms":[{"name":"Spom972h-EMC6","type":"exact"}],"termid":"PR:O59764"}


id: PBO:0085739
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p","termid":"PBO:0085739"}


id: MONDO:0005555
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation.","definition_xrefs":["EFO:0005758"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye accommodation disease","termid":"MONDO:0000926"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cycloplegia","secondary_identifiers":["UMLS:C0235238","ICD9:367.51","DOID:10033","MEDGEN:536368","SCTID:68158006","Wikipedia:Cycloplegia"],"synonyms":[{"name":"accommodative paresis","type":"related"},{"name":"ciliary muscle paresis","type":"exact"},{"name":"cycloplegia","type":"exact"},{"name":"cycloplegic paralysis of accommodation","type":"exact"},{"name":"loss of accommodation","type":"related"},{"name":"paralysis of accommodation","type":"related"},{"name":"paresis of accommodation","type":"exact"},{"name":"visual accommodation paralysis","type":"related"}],"termid":"MONDO:0005555","xrefs":{"Monarch":{"xref_id":"0005555"}}}


id: GO:0000437
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of transcription by RNA polymerase II","termid":"GO:0000122"},{"relation_name":"is_a","term_name":"carbon catabolite regulation of transcription from RNA polymerase II promoter","termid":"GO:0000429"},{"relation_name":"is_a","term_name":"carbon catabolite repression of transcription","termid":"GO:0045013"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"negatively_regulates","termid":"GO:0006351"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0006351"}],"interesting_parent_ids":["GO:0010467","GO:0006355","GO:0008150","GO:0006351"],"is_obsolete":false,"name":"carbon catabolite repression of transcription from RNA polymerase II promoter","synonyms":[{"name":"negative regulation of transcription from RNA polymerase II promoter by carbon catabolites","type":"exact"}],"termid":"GO:0000437"}


id: GO:0000228
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id: PBO:0034506
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id: GO:1900719
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of relaxation of smooth muscle","termid":"GO:1901080"},{"relation_name":"regulates","term_name":"uterine smooth muscle relaxation","termid":"GO:0044558"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of uterine smooth muscle relaxation","synonyms":[{"name":"regulation of smooth muscle relaxation of the uterus","type":"exact"}],"termid":"GO:1900719"}


id: GO:0061017
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.","definition_xrefs":["GOC:dph","PMID:15226394"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell differentiation","termid":"GO:0030855"},{"relation_name":"is_a","term_name":"stem cell differentiation","termid":"GO:0048863"},{"relation_name":"part_of","term_name":"liver development","termid":"GO:0001889"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hepatoblast differentiation","termid":"GO:0061017"}


id: PBO:0003849
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudouridine synthase (predicted)","termid":"PBO:0003849"}


id: GO:0075118
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id: PBO:0078156
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha variable 34","termid":"PBO:0078156"}


id: GO:0102159
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id: PBO:0039304
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ALK and LTK ligand 1","termid":"PBO:0039304"}


id: PBO:0044477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 20 subfamily A member 1","termid":"PBO:0044477"}


id: PBO:0004011
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Birt-Hogg-Dube syndrome","termid":"PBO:0004011"}


id: MONDO:1011893
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"neurodegenerative disease, non-human animal","termid":"MONDO:1012953"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurodegenerative vacuolar storage disease, non-human animal","secondary_identifiers":["OMIA:001954"],"termid":"MONDO:1011893","xrefs":{"Monarch":{"xref_id":"1011893"}}}


id: PBO:0060143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotrophin","termid":"PBO:0060143"}


id: PBO:0073233
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SUMO specific peptidase 6","termid":"PBO:0073233"}


id: MONDO:0002818
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete adrenal cortical adenocarcinoma (obsolete MONDO:0002818)","termid":"MONDO:0002818","xrefs":{"Monarch":{"xref_id":"0002818"}}}


id: PBO:0086527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; conserved across S. cerevisiae strains; YFL019C is not an essential gene","termid":"PBO:0086527"}


id: MONDO:1010153
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Darier disease that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"integumentary system disorder, non-human animal","termid":"MONDO:1011328"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Darier disease, non-human animal","secondary_identifiers":["OMIA:002265"],"termid":"MONDO:1010153","xrefs":{"Monarch":{"xref_id":"1010153"}}}


id: GO:0002609
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of dendritic cell antigen processing and presentation","termid":"GO:0002606"},{"relation_name":"is_a","term_name":"regulation of myeloid dendritic cell antigen processing and presentation","termid":"GO:0002607"},{"relation_name":"positively_regulates","term_name":"myeloid dendritic cell antigen processing and presentation","termid":"GO:0002469"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of myeloid dendritic cell antigen processing and presentation","synonyms":[{"name":"activation of myeloid dendritic cell antigen processing and presentation","type":"narrow"},{"name":"stimulation of myeloid dendritic cell antigen processing and presentation","type":"narrow"},{"name":"up regulation of myeloid dendritic cell antigen processing and presentation","type":"exact"},{"name":"up-regulation of myeloid dendritic cell antigen processing and presentation","type":"exact"},{"name":"upregulation of myeloid dendritic cell antigen processing and presentation","type":"exact"}],"termid":"GO:0002609"}


id: MONDO:1010787
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary hyperkeratosis characterized by generalized scaling in dogs due to a variation in the NIPAL4 gene.","definition_xrefs":["PMID:30741495"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"ichthyosis, dog","termid":"MONDO:1012978"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ichthyosis NIPAL4-related, dog","secondary_identifiers":["OMIA:001980-9615"],"termid":"MONDO:1010787","xrefs":{"Monarch":{"xref_id":"1010787"}}}


id: PBO:0085740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in transcription termination by RNA polymerase II; interacts with exonuclease Rat1p and Rai1p; has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition","termid":"PBO:0085740"}


id: GO:0019595
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucose catabolic process","termid":"GO:0006007"},{"relation_name":"is_a","term_name":"non-phosphorylated glucose metabolic process","termid":"GO:0046430"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"non-phosphorylated glucose catabolic process","synonyms":[{"name":"non-phosphorylated glucose breakdown","type":"exact"},{"name":"non-phosphorylated glucose catabolism","type":"exact"},{"name":"non-phosphorylated glucose degradation","type":"exact"}],"termid":"GO:0019595"}


id: GO:0071498
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to stress","termid":"GO:0033554"},{"relation_name":"is_a","term_name":"response to fluid shear stress","termid":"GO:0034405"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to fluid shear stress","termid":"GO:0071498"}


id: PBO:0036051
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_cell_cortex_of_cell_tip","termid":"PBO:0036051"}


id: GO:0005622
data:
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id: GO:1990663
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id: PBO:0044569
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id: GO:0046039
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id: MONDO:0014148
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Estrogen resistance syndrome is a rare, genetic endocrine disease characterized by estrogen-receptor insensitivity to estrogens and the presence of elevated estrogen and gonadotropin serum levels. Clinical manifestations include absent breast development and primary amenorrhea in association with multicystic ovaries and/or hypoplastic uterus in female patients, normal or abnormal gonadal development in male patients and markedly delayed bone maturation, persistence of open epiphyses, reduced bone mineral density, and variable tall stature in both sexes. Glucose intolerance, hyperinsulinemia and lipid abnormalities may also be present.","definition_xrefs":["Orphanet:785"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"reproductive system disorder","termid":"MONDO:0005039"},{"relation_name":"is_a","term_name":"endocrine system disorder","termid":"MONDO:0005151"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"estrogen resistance syndrome","secondary_identifiers":["OMIM:615363","SCTID:724555000","GARD:16548","UMLS:C3809250","icd11.foundation:1267163286","MEDGEN:815580"],"synonyms":[{"name":"ESTRR","type":"related"},{"name":"estrogen insensitivity","type":"related"},{"name":"estrogen resistance","type":"related"},{"name":"oestrogen insensitivity","type":"related"},{"name":"oestrogen resistance","type":"related"}],"termid":"MONDO:0014148","xrefs":{"Monarch":{"xref_id":"0014148"}}}


id: GO:0015427
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id: PBO:0059349
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id: PBO:0032705
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id: GO:0007633
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id: GO:0050950
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id: PBO:0087827
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id: PBO:0040235
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id: GO:0052184
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id: GO:0071339
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id: PBO:0066879
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 179","termid":"PBO:0066879"}


id: BFO:0000054
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id: FYPO:0006435
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id: PBO:0085139
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id: PBO:0113152
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Histone chaperone; regulates chromatin structure, transcription, mRNA 3'-end formation and genome stability; role in chromatin remodeling and nucleosome assembly; required for initiation of DNA replication, promoting origin licensing through MCM helicase loading; required for fidelity of promoter selection through maintenance of chromatin structure during transcription; required for H3K36 trimethylation but not dimethylation by Set2p","termid":"PBO:0113152"}


id: MONDO:0021927
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete arthrogryposis epileptic seizures migrational brain disorder (obsolete MONDO:0021927)","secondary_identifiers":["MESH:C537442"],"synonyms":[{"name":"arthrogryposis multiplex congenita with epileptic seizures and migrational brain disorder","type":"related"}],"termid":"MONDO:0021927","xrefs":{"Monarch":{"xref_id":"0021927"}}}


id: PBO:0006167
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_part","termid":"PBO:0006167"}


id: SO:0000095
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A plastid gene from leucoplast sequence.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"has_origin","term_name":"leucoplast_sequence","termid":"SO:0000747"},{"relation_name":"is_a","term_name":"plastid_gene","termid":"SO:0000090"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucoplast_gene","synonyms":[{"name":"leucoplast gene","type":"exact"}],"termid":"SO:0000095"}


id: PBO:0002924
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human U2AF35","termid":"PBO:0002924"}


id: PBO:0048294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanidinoacetate N-methyltransferase pseudogene 1","termid":"PBO:0048294"}


id: PBO:0075179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNRPE pseudogene 9","termid":"PBO:0075179"}


id: MONDO:0020049
data:
  {"annotated_genes":["SJAG_01806","SJAG_01548","SJAG_01286","SJAG_03424","SJAG_02231","SJAG_00112"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86556],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011402"},{"annotations":[85494,85493],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007925"},{"annotations":[85326],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012574"},{"annotations":[85401],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014848"},{"annotations":[85378],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008684"}]},"cv_name":"mondo","definition":"Chromosomal disorder in which the chromosomal anomaly involves an autosome.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosomal disorder","termid":"MONDO:0019040"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00112":null,"SJAG_01286":null,"SJAG_01548":null,"SJAG_01806":null,"SJAG_02231":null,"SJAG_03424":null},"genotype_count":0,"is_obsolete":false,"name":"autosomal anomaly","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:98127","UMLS:C5681496","MEDGEN:1843454","GARD:19417"],"synonyms":[{"name":"autosome chromosomal anomaly","type":"exact"},{"name":"chromosomal anomaly of autosome","type":"exact"}],"termid":"MONDO:0020049","terms_by_termid":{"MONDO:0007925":null,"MONDO:0008684":null,"MONDO:0011402":null,"MONDO:0012574":null,"MONDO:0014848":null},"xrefs":{"Monarch":{"xref_id":"0020049"}}}


id: PBO:0025552
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoribosylglycinamide formyltransferase","termid":"PBO:0025552"}


id: PBO:0071204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 45","termid":"PBO:0071204"}


id: PBO:0056047
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LTV1 ribosome biogenesis factor","termid":"PBO:0056047"}


id: GO:0000744
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena.","definition_xrefs":["GOC:pg","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"karyogamy","termid":"GO:0000741"},{"relation_name":"part_of","term_name":"conjugation with mutual genetic exchange","termid":"GO:0000748"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"karyogamy involved in conjugation with mutual genetic exchange","synonyms":[{"name":"karyogamy involved in conjugation without cellular fusion","type":"exact"}],"termid":"GO:0000744"}


id: GO:0052858
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.","definition_xrefs":["GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete peptidyl-lysine acetyltransferase activity (obsolete GO:0052858)","synonyms":[{"name":"acetyl-phosphate:peptidyl-L-lysine 6-N-acetyltransferase activity","type":"exact"},{"name":"acetyl-phosphate:peptidyl-L-lysine N6-acetyltransferase activity","type":"exact"},{"name":"peptidyl-lysine N(6)-acetyltransferase activity","type":"exact"},{"name":"peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor","type":"exact"},{"name":"peptidyl-lysine N6-acetyltransferase activity","type":"exact"}],"termid":"GO:0052858"}


id: GO:1902399
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any detection of stimulus that is involved in G1 DNA damage checkpoint.","definition_xrefs":["GOC:TermGenie","GOC:mtg_cell_cycle"],"gene_count":0,"genotype_count":0,"name":"obsolete detection of stimulus involved in G1 DNA damage checkpoint (obsolete GO:1902399)","synonyms":[{"name":"detection of stimulus involved in G1/S DNA damage checkpoint","type":"exact"},{"name":"perception of stimulus involved in G1 DNA damage checkpoint","type":"related"},{"name":"perception of stimulus involved in G1/S DNA damage checkpoint","type":"related"},{"name":"stimulus detection involved in G1 DNA damage checkpoint","type":"exact"},{"name":"stimulus detection involved in G1/S DNA damage checkpoint","type":"exact"},{"name":"stimulus sensing involved in G1 DNA damage checkpoint","type":"related"},{"name":"stimulus sensing involved in G1/S DNA damage checkpoint","type":"related"}],"termid":"GO:1902399"}


id: PBO:0045272
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynamin 1 pseudogene 19","termid":"PBO:0045272"}


id: MONDO:0016884
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of chromosome 2","termid":"MONDO:0016867"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial deletion of the short arm of chromosome 2","secondary_identifiers":["Orphanet:261866","GARD:20807","MEDGEN:1826019","icd11.foundation:1610083208","UMLS:C5679664"],"synonyms":[{"name":"partial deletion of chromosome 2p","type":"exact"},{"name":"partial deletion of the short arm of chromosome type 2","type":"exact"},{"name":"partial monosomy of chromosome 2p","type":"exact"},{"name":"partial monosomy of the short arm of chromosome 2","type":"exact"}],"termid":"MONDO:0016884","xrefs":{"Monarch":{"xref_id":"0016884"}}}


id: MONDO:0004167
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete lung clear cell carcinoma (obsolete MONDO:0004167)","secondary_identifiers":["SCTID:254630009","DOID:7267"],"termid":"MONDO:0004167","xrefs":{"Monarch":{"xref_id":"0004167"}}}


id: PBO:0074356
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMC3 pseudogene 1","termid":"PBO:0074356"}


id: MONDO:0017052
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Intermediate maple syrup urine disease (intermediate MSUD) is a milder form of MSUD characterized by persistently raised branched-chain amino acids (BCAAs) and ketoacids, but fewer or no acute episodes of decompensation.","definition_xrefs":["Orphanet:268162"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maple syrup urine disease","termid":"MONDO:0009563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"intermediate maple syrup urine disease","secondary_identifiers":["UMLS:C1621920","SCTID:405287008","MEDGEN:301223","GARD:17264","NANDO:2201079"],"synonyms":[{"name":"Intermediate BCKD deficiency","type":"exact"},{"name":"Intermediate MSUD","type":"exact"},{"name":"Intermediate branched-chain 2-ketoacid dehydrogenase deficiency","type":"exact"},{"name":"Intermediate branched-chain alpha-ketoacid dehydrogenase deficiency","type":"exact"},{"name":"intermediate maple syrup urine disease","type":"exact"}],"termid":"MONDO:0017052","xrefs":{"Monarch":{"xref_id":"0017052"}}}


id: PBO:0088394
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNase P subunit Rpr2","termid":"PBO:0088394"}


id: FYPO:0005874
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of medial membrane band assembly is decreased. Medial membrane band assembly is the assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.","definition_xrefs":["PomBase:mah","GO:0032130"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cytokinesis","termid":"FYPO:0000032"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000032","FYPO:0001985","FYPO:0000631","FYPO:0005447","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased rate of medial membrane band assembly","synonyms":[{"name":"decreased rate of medial membrane band assembly during mitotic cell cycle","type":"related"},{"name":"decreased rate of medial membrane band assembly during vegetative growth","type":"exact"},{"name":"decreased rate of medial membrane band formation","type":"exact"},{"name":"reduced rate of medial membrane band assembly","type":"exact"}],"termid":"FYPO:0005874"}


id: PBO:0038960
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosine kinase","termid":"PBO:0038960"}


id: GO:0035118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"embryonic appendage morphogenesis","termid":"GO:0035113"},{"relation_name":"is_a","term_name":"pectoral fin morphogenesis","termid":"GO:0035138"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"embryonic pectoral fin morphogenesis","termid":"GO:0035118"}


