# terms

id: MONDO:0009663
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mucus inspissation of respiratory tract","secondary_identifiers":["MEDGEN:340702","OMIM:253240","UMLS:C1854729","MESH:C565366"],"synonyms":[{"name":"mucus inspissation of respiratory tract","type":"exact"}],"termid":"MONDO:0009663","xrefs":{"Monarch":{"xref_id":"0009663"}}}


id: PBO:0058486
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5681a","termid":"PBO:0058486"}


id: MONDO:1010439
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cardiomyopathy that occurs in chicken.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bird disease","termid":"MONDO:0024905"},{"relation_name":"is_a","term_name":"cardiomyopathy, non-human animal","termid":"MONDO:1010010"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cardiomyopathy, chicken","secondary_identifiers":["OMIA:000160-9031"],"termid":"MONDO:1010439","xrefs":{"Monarch":{"xref_id":"1010439"}}}


id: PBO:0049348
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"general transcription factor IIi pseudogene 6","termid":"PBO:0049348"}


id: MOD:01874
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-alanine residue to N-carboxy-L-valine.","definition_xrefs":["PubMed:4593770","PubMed:4647257","PubMed:8312270","PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-valine residue","termid":"MOD:00920"},{"relation_name":"is_a","term_name":"carboxylated residue","termid":"MOD:01152"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-carboxy-L-valine","synonyms":[{"name":"(S)-2-carboxyamino-propanoic acid","type":"exact"},{"name":"2-carbamic-propanoic acid","type":"exact"},{"name":"N-carboxymethionine","type":"exact"}],"termid":"MOD:01874"}


id: GO:0007054
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spindle assembly involved in male meiosis","termid":"GO:0007053"},{"relation_name":"part_of","term_name":"male meiosis I","termid":"GO:0007141"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0000226"},{"rel_name":"part_of","termid":"GO:0140013"},{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007049","GO:0044085","GO:0008150","GO:0000226","GO:0007010","GO:0140013"],"is_obsolete":false,"name":"spindle assembly involved in male meiosis I","synonyms":[{"name":"male meiosis I spindle assembly","type":"related"}],"termid":"GO:0007054"}


id: GO:0006971
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.","definition_xrefs":["GOC:jl","PMID:12598593"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to osmotic stress","termid":"GO:0006970"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hypotonic response","synonyms":[{"name":"hypo-osmotic response","type":"exact"}],"termid":"GO:0006971"}


id: PBO:0040354
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase membrane subunit g pseudogene 3","termid":"PBO:0040354"}


id: PBO:0081863
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 799","termid":"PBO:0081863"}


id: PBO:0048251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin G associated kinase","termid":"PBO:0048251"}


id: PBO:0067176
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 233, pseudogene","termid":"PBO:0067176"}


id: MOD:00063
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-valine residue to N-acetyl-L-valine.","definition_xrefs":["PubMed:1735421","RESID:AA0054"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-valine residue","termid":"MOD:00920"},{"relation_name":"is_a","term_name":"alpha-amino acetylated residue","termid":"MOD:01458"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00408"}],"interesting_parent_ids":["MOD:00408"],"is_obsolete":false,"name":"N-acetyl-L-valine","synonyms":[{"name":"(2S)-2-acetamido-3-methylbutanoic acid","type":"exact"},{"name":"2-acetylamino-3-methylbutanoic acid","type":"exact"},{"name":"2-acetylazanyl-3-methylbutanoic acid","type":"exact"},{"name":"AcVal","type":"exact"},{"name":"MOD_RES N-acetylvaline","type":"exact"},{"name":"N-acetyl-L-valine","type":"exact"},{"name":"N-acetylated L-valine","type":"exact"},{"name":"N-acetylvaline","type":"exact"}],"termid":"MOD:00063"}


id: GO:0009129
data:
  {"annotated_genes":["SJAG_03164","SJAG_04709","SJAG_04713","SJAG_00444","SJAG_03708","SJAG_04487","SJAG_00694","SJAG_00197","SJAG_00964","SJAG_04627","SJAG_04354","SJAG_03771","SJAG_00533"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[57240,59403,61068,61780,59090],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044205"},{"annotations":[67731],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009224"},{"annotations":[69705,79135],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006231"},{"annotations":[69704,79243],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006226"},{"annotations":[87227,67732,88211,91734,92735],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044206"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside monophosphate metabolic process","termid":"GO:0009123"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00197":null,"SJAG_00444":null,"SJAG_00533":null,"SJAG_00694":null,"SJAG_00964":null,"SJAG_03164":null,"SJAG_03708":null,"SJAG_03771":null,"SJAG_04354":null,"SJAG_04487":null,"SJAG_04627":null,"SJAG_04709":null,"SJAG_04713":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"pyrimidine nucleoside monophosphate metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"pyrimidine nucleoside monophosphate metabolism","type":"exact"}],"termid":"GO:0009129","terms_by_termid":{"GO:0006226":null,"GO:0006231":null,"GO:0009224":null,"GO:0044205":null,"GO:0044206":null}}


id: GO:1990454
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.","definition_xrefs":["GOC:ame","PMID:12946355"],"direct_ancestors":[{"relation_name":"is_a","term_name":"voltage-gated calcium channel complex","termid":"GO:0005891"},{"relation_name":"part_of","term_name":"T-tubule","termid":"GO:0030315"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005886","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"L-type voltage-gated calcium channel complex","synonyms":[{"name":"cardiac muscle L-type voltage-gated calcium channel complex","type":"narrow"},{"name":"skeletal muscle L-type voltage-gated calcium channel complex","type":"narrow"}],"termid":"GO:1990454"}


id: MONDO:0100588
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any congenital disorder of glycosylation in which the cause of the disease is a mutation in FAM20B.","definition_xrefs":["PMID:38653092","PMID:37298583","PMID:30847897"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital disorder of glycosylation","termid":"MONDO:0015286"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0024322","MONDO:0005066"],"is_obsolete":false,"name":"FAM20B-congenital disorder of glycosylation","synonyms":[{"name":"FAM20B-CDG","type":"exact"},{"name":"FAM20B-congenital disorder of glycosylation","type":"exact"}],"termid":"MONDO:0100588","xrefs":{"Monarch":{"xref_id":"0100588"}}}


id: MONDO:0020299
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete spinocerebellar ataxia type 15/16 (obsolete MONDO:0020299)","termid":"MONDO:0020299","xrefs":{"Monarch":{"xref_id":"0020299"}}}


id: GO:0099065
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.","definition_xrefs":["GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete integral component of spine apparatus membrane (obsolete GO:0099065)","termid":"GO:0099065"}


id: PBO:0090107
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GDP dissociation inhibitor Rdi1","termid":"PBO:0090107"}


id: GO:1903289
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of ATP catabolic process.","definition_xrefs":["GOC:BHF","GOC:rl","GOC:TermGenie","PMID:10636900","GO_REF:0000058"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of ATP catabolic process (obsolete GO:1903289)","synonyms":[{"name":"regulation of ATP breakdown","type":"exact"},{"name":"regulation of ATP catabolism","type":"exact"},{"name":"regulation of ATP degradation","type":"exact"},{"name":"regulation of ATP hydrolysis","type":"narrow"}],"termid":"GO:1903289"}


id: MONDO:0006898
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the tissues around a joint. (Dorland, 27th ed)","definition_xrefs":["MESH:D010489"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bursitis","termid":"MONDO:0002471"},{"relation_name":"is_a","term_name":"arthritic joint disease","termid":"MONDO:0005578"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"periarthritis","secondary_identifiers":["MEDGEN:45397","SCTID:50921008","UMLS:C0031037","EFO:1001097","DOID:2964","MedDRA:10034464"],"termid":"MONDO:0006898","xrefs":{"Monarch":{"xref_id":"0006898"}}}


id: PR:000050526
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the hhf1 gene in Schizosaccharomyces pombe.","definition_xrefs":["PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein","termid":"PR:000000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone H4, hhf1 gene translation product (Schizosaccharomyces pombe)","pombase_gene_id":"SPAC1834.03c","termid":"PR:000050526"}


id: MONDO:0020626
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete yt blood group antigen (obsolete MONDO:0020626)","secondary_identifiers":["OMIM:112100"],"synonyms":[{"name":"Cartwright Antigen","type":"related"},{"name":"YT BLOOD GROUP ANTIGEN","type":"related"},{"name":"blood group, Yt system","type":"exact"}],"termid":"MONDO:0020626","xrefs":{"Monarch":{"xref_id":"0020626"}}}


id: PBO:0067551
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 702, pseudogene","termid":"PBO:0067551"}


id: PBO:0082731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the Rpd3L histone deacetylase complex; involved in histone deacetylation; protein abundance increases in response to DNA replication stress","termid":"PBO:0082731"}


id: PBO:0075662
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spectrin beta, non-erythrocytic 2","termid":"PBO:0075662"}


id: MONDO:0006422
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm that arises from the glandular epithelium of the small intestine. It is characterized by tubular and villous architectural patterns. The neoplastic glandular cells have dysplastic features.","definition_xrefs":["NCIT:C43553"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenoma of small intestine","termid":"MONDO:0021303"},{"relation_name":"is_a","term_name":"tubulovillous adenoma","termid":"MONDO:0024661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"small intestinal tubulovillous adenoma","secondary_identifiers":["MEDGEN:354182","EFO:1000539","UMLS:C1710113"],"termid":"MONDO:0006422","xrefs":{"Monarch":{"xref_id":"0006422"}}}


id: MONDO:1040007
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare congenital brain disorder characterized by complete or almost near-complete unilateral absence of the cortical cortex, which is filled by a sac of cerebrospinal fluid. The presumed cause is a prenatal vascular disruption with occlusion of the carotid artery territories ipsilateral to the damaged brain.","definition_xrefs":["PMID:23324549"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydranencephaly","termid":"MONDO:0016344"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"hemihydranencephaly","secondary_identifiers":["MEDGEN:199609","UMLS:C0751210"],"synonyms":[{"name":"hemi-hydranencephaly","type":"exact"}],"termid":"MONDO:1040007","xrefs":{"Monarch":{"xref_id":"1040007"}}}


id: MONDO:0016639
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Lower limb malformation-hypospadias syndrome is a rare developmental defect during embryogenesis characterized by severe, uni- or bilateral lower limb malformations (incl. tibial hypoplasia, split and rocker bottom-shaped feet, and oligosyndactyly), normal upper limbs and hypospadias. Additional dysmorphic features (e.g. short neck and low-set, large ears), atrial septal defect, ureteropelvic junction stenosis and slight septation of the spleen, have also been reported. There have been no further descriptions in the literature since 1977.","definition_xrefs":["Orphanet:2487"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lower limb deficiency-hypospadias syndrome","secondary_identifiers":["GARD:18773","UMLS:C2930962","MEDGEN:418952","MESH:C535640"],"synonyms":[{"name":"Fried-Goldberg-Mundel syndrome","type":"exact"},{"name":"lower limb malformation-hypospadias syndrome","type":"related"}],"termid":"MONDO:0016639","xrefs":{"Monarch":{"xref_id":"0016639"}}}


id: PBO:0030964
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K9_trimethylation_at_centromere_inner_repeat","termid":"PBO:0030964"}


id: GO:0032707
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cytokine production","termid":"GO:0001818"},{"relation_name":"is_a","term_name":"regulation of interleukin-23 production","termid":"GO:0032667"},{"relation_name":"negatively_regulates","term_name":"interleukin-23 production","termid":"GO:0032627"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of interleukin-23 production","secondary_identifiers":["GO:0045397"],"synonyms":[{"name":"down regulation of interleukin-23 production","type":"exact"},{"name":"down-regulation of interleukin-23 production","type":"exact"},{"name":"downregulation of interleukin-23 production","type":"exact"},{"name":"inhibition of interleukin-23 production","type":"narrow"},{"name":"negative regulation of IL-23 production","type":"exact"},{"name":"negative regulation of interleukin-23 biosynthetic process","type":"narrow"}],"termid":"GO:0032707"}


id: GO:0072110
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell proliferation involved in kidney development","termid":"GO:0072111"},{"relation_name":"part_of","term_name":"glomerular mesangium development","termid":"GO:0072109"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glomerular mesangial cell proliferation","termid":"GO:0072110"}


id: MONDO:0970998
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"auroneurodental syndrome","secondary_identifiers":["OMIM:620830","MEDGEN:1861965","UMLS:C5889721"],"termid":"MONDO:0970998","xrefs":{"Monarch":{"xref_id":"0970998"}}}


id: GO:0021885
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of a cell from one site to another at least one of which is located in the forebrain.","definition_xrefs":["GOC:dph","GO_REF:0000021","GOC:dgh","GOC:jid","GOC:cls"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell migration","termid":"GO:0016477"},{"relation_name":"part_of","term_name":"forebrain development","termid":"GO:0030900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"forebrain cell migration","termid":"GO:0021885"}


id: GO:0009579
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.","definition_xrefs":["ISBN:0198506732","GOC:mtg_sensu","GOC:ds"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular membraneless organelle","termid":"GO:0043232"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"thylakoid","secondary_identifiers":["Wikipedia:Thylakoid"],"synonyms":[{"name":"photosynthetic membrane","type":"related"}],"termid":"GO:0009579"}


id: MOD:00757
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-proline residue to O4-galactosyl-L-hydroxyproline.","definition_xrefs":["RESID:AA0389"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-proline residue","termid":"MOD:00915"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O4-galactosyl-L-hydroxyproline","synonyms":[{"name":"(2S,4R)-4-(beta-D-galactopyranosyloxy)pyrrolidine-2-carboxylic acid","type":"exact"},{"name":"4-(beta-D-galactopyranosyloxy)proline","type":"exact"},{"name":"4-(galactosyloxy)proline","type":"exact"},{"name":"CARBOHYD O-linked (Gal) hydroxyproline","type":"exact"},{"name":"O4-galactosyl-L-hydroxyproline","type":"exact"},{"name":"O4-glycosyl-hydroxyproline","type":"exact"},{"name":"beta-galactopyranosyl-4-hydroxyproline","type":"exact"}],"termid":"MOD:00757"}


id: PR:Q9P6I7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dea2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P6I7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenine deaminase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1198.02","synonyms":[{"name":"AAH (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ADE (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-dea2","type":"exact"},{"name":"adenine aminohydrolase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P6I7"}


id: PBO:0051094
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy joining 4","termid":"PBO:0051094"}


id: GO:0009960
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.","definition_xrefs":["GOC:sm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"is_a","term_name":"tissue development","termid":"GO:0009888"},{"relation_name":"part_of","term_name":"seed development","termid":"GO:0048316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endosperm development","termid":"GO:0009960"}


id: GO:1901286
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.","definition_xrefs":["GOC:TermGenie","UniPathway:UPA00782","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic process","termid":"GO:0008152"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"iron-sulfur-molybdenum cofactor metabolic process","synonyms":[{"name":"FeMo-co metabolic process","type":"exact"},{"name":"FeMo-co metabolism","type":"exact"},{"name":"iron-molybdenum cofactor metabolic process","type":"exact"},{"name":"iron-molybdenum cofactor metabolism","type":"exact"},{"name":"iron-sulfur-molybdenum cofactor metabolism","type":"exact"}],"termid":"GO:1901286"}


id: PBO:0031340
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_N-ethylmaleimide","termid":"PBO:0031340"}


id: PBO:0029112
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_meiotic_cell_cycle_process","termid":"PBO:0029112"}


id: GO:0018888
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid metabolic process","termid":"GO:0032787"},{"relation_name":"is_a","term_name":"organohalogen metabolic process","termid":"GO:0090345"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"3-chloroacrylic acid metabolic process","secondary_identifiers":["UM-BBD_pathwayID:caa"],"synonyms":[{"name":"3-chloroacrylic acid metabolism","type":"exact"}],"termid":"GO:0018888"}


id: MONDO:0011910
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autosomal dominant limb-girdle muscular dystrophy type 1C (obsolete MONDO:0011910)","secondary_identifiers":["OMIM:607801","SCTID:719986000","DOID:0110302","MESH:C563362","NCIT:C148318","Orphanet:265"],"termid":"MONDO:0011910","xrefs":{"Monarch":{"xref_id":"0011910"}}}


id: PBO:0045903
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endonuclease/exonuclease/phosphatase family domain containing 1","termid":"PBO:0045903"}


id: MONDO:0033552
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete blood group, lewis system (obsolete MONDO:0033552)","secondary_identifiers":["OMIM:618983"],"synonyms":[{"name":"BLOOD GROUP, LEWIS SYSTEM","type":"related"},{"name":"LE","type":"related"},{"name":"Lewis Blood Group System","type":"related"},{"name":"Lewis-Negative Phenotype","type":"related"},{"name":"blood group, Lewis","type":"exact"}],"termid":"MONDO:0033552","xrefs":{"Monarch":{"xref_id":"0033552"}}}


id: GO:0048368
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesoderm development","termid":"GO:0007498"},{"relation_name":"is_a","term_name":"mesenchyme development","termid":"GO:0060485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lateral mesoderm development","synonyms":[{"name":"lateral plate mesoderm development","type":"exact"}],"termid":"GO:0048368"}


id: PBO:0075501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spermatogenesis and centriole associated 1","termid":"PBO:0075501"}


id: PBO:0057284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 504","termid":"PBO:0057284"}


id: PBO:0073331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serpin family A member 7","termid":"PBO:0073331"}


id: GO:0045884
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.","definition_xrefs":["GOC:mtg_apoptosis","GOC:tb","GOC:dph","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of survival gene product expression (obsolete GO:0045884)","synonyms":[{"name":"regulation of survival gene product activity","type":"broad"},{"name":"regulation of survival gene product expression","type":"exact"},{"name":"regulation of survival gene products","type":"broad"}],"termid":"GO:0045884"}


id: PBO:0059685
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 51","termid":"PBO:0059685"}


id: PBO:0003818
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally regulated by Fep1","termid":"PBO:0003818"}


id: PBO:0082351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p); UTR1 has a paralog, YEF1, that arose from the whole genome duplication","termid":"PBO:0082351"}


id: PBO:0055445
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2876","termid":"PBO:0055445"}


id: PBO:0067149
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 199, pseudogene","termid":"PBO:0067149"}


id: PBO:0076193
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SUMO2 pseudogene 2","termid":"PBO:0076193"}


id: PBO:0058340
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR4713 host gene","termid":"PBO:0058340"}


id: PBO:0047532
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FGD5 antisense RNA 1","termid":"PBO:0047532"}


id: PBO:0045505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dentin sialophosphoprotein","termid":"PBO:0045505"}


id: SO:0002125
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A joining gene that rearranges at the DNA level and codes the joining region of the variable domain of an immunoglobulin chain.","definition_xrefs":["GENCODE:http://www.gencodegenes.org/gencode_biotypes.html","IGMT:http://www.imgt.org/IMGTScientificChart/SequenceDescription/Keywords.php"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immunoglobulin_gene","termid":"SO:0002122"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IG_J_gene","synonyms":[{"name":"IG_joining_gene","type":"exact"},{"name":"Immunoglobulin_Joining_Gene","type":"exact"},{"name":"immunoglobulin_J_gene","type":"exact"}],"termid":"SO:0002125"}


id: GO:0060780
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.","definition_xrefs":["GOC:dph","GOC:sdb_2009","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leaflet morphogenesis","termid":"GO:0060794"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"intercalary leaflet morphogenesis","termid":"GO:0060780"}


id: MONDO:0002046
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The use of alcoholic beverages to excess, either on individual occasions (\\\"binge drinking\\\") or as a regular practice.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"substance abuse","termid":"MONDO:0002491"},{"relation_name":"is_a","term_name":"alcohol-related disorders","termid":"MONDO:0021698"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alcohol abuse","secondary_identifiers":["UMLS:C0085762","ICD9:305.0","ICD9:305.00","MEDGEN:39339","MESH:D000437","SCTID:15167005","DOID:1574"],"synonyms":[{"name":"abuse, alcohol","type":"related"},{"name":"addiction, alcohol","type":"related"},{"name":"alcohol abuse","type":"exact"},{"name":"alcohol addiction","type":"related"},{"name":"alcohol dependence","type":"related"},{"name":"alcohol use disorder","type":"related"},{"name":"alcoholic intoxication, chronic","type":"related"},{"name":"alcoholism","type":"related"},{"name":"chronic alcoholic intoxication","type":"related"},{"name":"dependence, alcohol","type":"related"},{"name":"ethanol abuse","type":"exact"},{"name":"intoxication, chronic alcoholic","type":"related"}],"termid":"MONDO:0002046","xrefs":{"Monarch":{"xref_id":"0002046"}}}


id: PBO:0054882
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2296","termid":"PBO:0054882"}


id: MOD:02003
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydroxy hydrogen atom of L-serine with an acyl group.","direct_ancestors":[{"relation_name":"is_a","term_name":"O-acylated residue","termid":"MOD:00671"},{"relation_name":"is_a","term_name":"modified L-serine residue","termid":"MOD:00916"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O3-acylated L-serine","termid":"MOD:02003"}


id: FYPO:0007573
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins earlier than normal and the rate, or speed, of ring contraction is increased.","definition_xrefs":["PomBase:vw","PomBase:mah","PMID:25451933"],"direct_ancestors":[{"relation_name":"has_part","term_name":"premature actomyosin contractile ring contraction","termid":"FYPO:0004430"},{"relation_name":"has_part","term_name":"increased rate of actomyosin contractile ring contraction","termid":"FYPO:0006897"},{"relation_name":"is_a","term_name":"premature actomyosin contractile ring contraction","termid":"FYPO:0004430"},{"relation_name":"is_a","term_name":"increased rate of actomyosin contractile ring contraction","termid":"FYPO:0006897"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000032"},{"rel_name":"has_part","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0004803"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0004803"}],"interesting_parent_ids":["FYPO:0004803","FYPO:0000631","FYPO:0001320","FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0000032"],"is_obsolete":false,"name":"premature actomyosin contractile ring contraction with increased contraction rate","synonyms":[{"name":"advanced actomyosin contractile ring contraction with increased contraction rate","type":"exact"},{"name":"premature actomyosin contractile ring constriction with increased constriction rate","type":"exact"},{"name":"premature actomyosin contractile ring constriction with increased rate of contraction","type":"exact"},{"name":"premature actomyosin contractile ring contraction with increased contraction rate during mitotic cell cycle","type":"related"},{"name":"premature actomyosin contractile ring contraction with increased contraction rate during vegetative growth","type":"exact"},{"name":"premature contractile ring contraction with increased rate of contraction","type":"exact"},{"name":"premature cytokinetic contractile ring contraction with increased rate of contraction","type":"exact"},{"name":"premature mitotic actomyosin contractile ring contraction with increased contraction rate","type":"exact"},{"name":"premature, fast actomyosin contractile ring contraction","type":"exact"}],"termid":"FYPO:0007573"}


id: MONDO:0009359
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"hereditary lethal multiple congenital anomalies/dysmorphic syndrome","termid":"MONDO:0043009"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"multinucleated neurons-anhydramnios-renal dysplasia-cerebellar hypoplasia-hydranencephaly syndrome","secondary_identifiers":["MESH:C565507","OMIM:236500","DOID:0080327","Orphanet:500135","GARD:17922","UMLS:C1856053","MEDGEN:343465"],"synonyms":[{"name":"MARCH","type":"related"},{"name":"MARCH syndrome","type":"exact"},{"name":"hydranencephaly with renal aplasia-dysplasia","type":"exact"},{"name":"multinucleated neurons, anhydramnios, renal dysplasia, cerebellar Hypoplasia, and hydranencephaly","type":"related"},{"name":"multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly","type":"related"}],"termid":"MONDO:0009359","xrefs":{"Monarch":{"xref_id":"0009359"}}}


id: MONDO:0017255
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder characterized by inflammation of the entire uvea which includes the iris, ciliary body, and choroid. Causes include systemic infections, sarcoidosis, and cancers.","definition_xrefs":["NCIT:C84989"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uveitis","termid":"MONDO:0020283"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"panuveitis","secondary_identifiers":["EFO:1001082","ICD9:360.12","SCTID:75614007","MEDGEN:45303","Orphanet:280898","MedDRA:10033687","icd11.foundation:1125547814","HP:0012121","MESH:D015864","UMLS:C0030343","DOID:12030","GARD:8577"],"synonyms":[{"name":"diffuse uveitis","type":"exact"},{"name":"panuveitis","type":"exact"},{"name":"panuveitis (disease)","type":"exact"},{"name":"total uveitis","type":"exact"}],"termid":"MONDO:0017255","xrefs":{"Monarch":{"xref_id":"0017255"}}}


id: PBO:0075025
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 115-36","termid":"PBO:0075025"}


id: PBO:0070089
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 3 pseudogene","termid":"PBO:0070089"}


id: GO:0070094
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of glucagon secretion","termid":"GO:0070092"},{"relation_name":"is_a","term_name":"positive regulation of peptide hormone secretion","termid":"GO:0090277"},{"relation_name":"positively_regulates","term_name":"glucagon secretion","termid":"GO:0070091"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0006810","GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of glucagon secretion","synonyms":[{"name":"activation of glucagon secretion","type":"narrow"},{"name":"stimulation of glucagon secretion","type":"narrow"},{"name":"up regulation of glucagon secretion","type":"exact"},{"name":"up-regulation of glucagon secretion","type":"exact"},{"name":"upregulation of glucagon secretion","type":"exact"}],"termid":"GO:0070094"}


id: GO:1901067
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of ferulate.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phenol-containing compound catabolic process","termid":"GO:0019336"},{"relation_name":"is_a","term_name":"ferulate metabolic process","termid":"GO:0033494"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"},{"relation_name":"is_a","term_name":"olefinic compound catabolic process","termid":"GO:0120256"},{"relation_name":"is_a","term_name":"ether catabolic process","termid":"GO:1901502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044248"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0044248"],"is_obsolete":false,"name":"ferulate catabolic process","synonyms":[{"name":"ferulate breakdown","type":"exact"},{"name":"ferulate catabolism","type":"exact"},{"name":"ferulate degradation","type":"exact"}],"termid":"GO:1901067"}


id: MONDO:0005564
data:
  {"annotated_genes":["SJAG_03689","SJAG_04213","SJAG_00579","SJAG_05313","SJAG_04755","SJAG_01111"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87110],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007959"},{"annotations":[86122],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011014"},{"annotations":[84958,84959],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012252"},{"annotations":[87096,87097],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013224"}]},"cv_name":"mondo","definition":"A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003","definition_xrefs":["NCIT:C3264"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm","termid":"MONDO:0005070"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00579":null,"SJAG_01111":null,"SJAG_03689":null,"SJAG_04213":null,"SJAG_04755":null,"SJAG_05313":null},"genotype_count":0,"is_obsolete":false,"name":"embryonal neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ONCOTREE:EMBT","MESH:D009373","EFO:0005784","UMLS:C0027654","DOID:688","MEDGEN:45034"],"synonyms":[{"name":"EMBT","type":"related"},{"name":"embryo neoplasm","type":"exact"},{"name":"embryonal cancer","type":"related"},{"name":"embryonal neoplasm","type":"exact"},{"name":"embryonal tumor","type":"exact"},{"name":"embryonal tumour","type":"exact"}],"termid":"MONDO:0005564","terms_by_termid":{"MONDO:0007959":null,"MONDO:0011014":null,"MONDO:0012252":null,"MONDO:0013224":null},"xrefs":{"Monarch":{"xref_id":"0005564"}}}


id: PBO:0082927
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic aldehyde dehydrogenase; involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose","termid":"PBO:0082927"}


id: PBO:0051999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"JARID2 divergent transcript","termid":"PBO:0051999"}


id: GO:1990317
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.","definition_xrefs":["GOC:bhm","PMID:12058072"],"direct_ancestors":[{"relation_name":"is_a","term_name":"serine/threonine protein kinase complex","termid":"GO:1902554"},{"relation_name":"part_of","term_name":"cellular bud neck septin ring","termid":"GO:0000144"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005938"}],"interesting_parent_ids":["GO:0005575","GO:0005938","GO:0005737","GO:0032991"],"is_obsolete":false,"name":"Gin4 complex","synonyms":[{"name":"Gin4-septin complex","type":"exact"}],"termid":"GO:1990317"}


id: PBO:0090473
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRAPP I, II, and III complex subunit Trs23","termid":"PBO:0090473"}


id: MONDO:0100044
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acrofrontofacionasal dysostosis","termid":"MONDO:0008715"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"acrofrontofacionasal dysostosis 1","secondary_identifiers":["OMIM:201180","MEDGEN:1632008","MESH:C538186","UMLS:C4551987"],"synonyms":[{"name":"AFFN dysostosis 1","type":"exact"},{"name":"acrofrontofacionasal dysostosis 1","type":"exact"},{"name":"acrofrontofacionasal dysostosis type 1","type":"exact"}],"termid":"MONDO:0100044","xrefs":{"Monarch":{"xref_id":"0100044"}}}


id: MONDO:0100259
data:
  {"annotated_genes":["SJAG_02619"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86614],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008953"},{"annotations":[86958],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011101"}]},"cv_name":"mondo","definition":"Any Zellweger spectrum disorder in which the cause of the disease is a mutation in the PEX1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Zellweger spectrum disorders","termid":"MONDO:0019609"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02619":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0019053"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005244","MONDO:0006025","MONDO:0005559","MONDO:0019053"],"is_obsolete":false,"name":"peroxisome biogenesis disorder due to PEX1 defect","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"PEX1 related Zellweger spectrum disorder","type":"exact"},{"name":"peroxisome biogenesis disorder due to PEX1 defect","type":"exact"}],"termid":"MONDO:0100259","terms_by_termid":{"MONDO:0008953":null,"MONDO:0011101":null},"xrefs":{"Monarch":{"xref_id":"0100259"}}}


id: PBO:0040371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP5PB pseudogene 8","termid":"PBO:0040371"}


id: PBO:0114425
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliary microtubule inner protein 7","termid":"PBO:0114425"}


id: PBO:0041038
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BRCA1 associated ATM activator 1","termid":"PBO:0041038"}


id: PBO:0075964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"StAR related lipid transfer domain containing 5","termid":"PBO:0075964"}


id: PBO:0070932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L17 pseudogene 40","termid":"PBO:0070932"}


id: GO:0044721
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.","definition_xrefs":["PMID:21976670"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex disassembly","termid":"GO:0032984"},{"relation_name":"part_of","term_name":"protein import into peroxisome matrix","termid":"GO:0016558"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0007031"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0055085","GO:0006810","GO:0007031","GO:0008150"],"is_obsolete":false,"name":"protein import into peroxisome matrix, substrate release","termid":"GO:0044721"}


id: SO:0000577
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region of chromosome where the spindle fibers attach during mitosis and meiosis.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosomal_structural_element","termid":"SO:0000628"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centromere","secondary_identifiers":["http://en.wikipedia.org/wiki/Centromere"],"synonyms":[{"name":"INSDC_feature:centromere","type":"exact"}],"termid":"SO:0000577"}


id: MONDO:0024289
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete disorder of bilirubin metabolism (obsolete MONDO:0024289)","termid":"MONDO:0024289","xrefs":{"Monarch":{"xref_id":"0024289"}}}


id: PBO:0001645
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytosolic thioredoxin Trx1","termid":"PBO:0001645"}


id: FYPO:0003445
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to ultraviolet light.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased duration of mitotic DNA damage checkpoint","termid":"FYPO:0002341"},{"relation_name":"is_a","term_name":"abnormal mitotic DNA damage checkpoint during cellular response to UV","termid":"FYPO:0002900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000298","FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"increased duration of mitotic DNA damage checkpoint during cellular response to UV","synonyms":[{"name":"delayed DNA damage checkpoint deactivation during cellular response to UV","type":"exact"},{"name":"prolonged DNA damage checkpoint during cellular response to UV","type":"exact"}],"termid":"FYPO:0003445"}


id: PATO:0002381
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A composition quality inhering in an bearer by virtue of the presence of long chain aliphatic lipids on the surface of an organism.","definition_xrefs":["PATOC:lm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"composition","termid":"PATO:0000025"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"waxiness","termid":"PATO:0002381"}


id: PBO:0064070
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi-interacting RNA cluster 104","termid":"PBO:0064070"}


id: PBO:0065788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"queuine tRNA-ribosyltransferase catalytic subunit 1 pseudogene 1","termid":"PBO:0065788"}


id: PBO:0068267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonuclease A family member 3","termid":"PBO:0068267"}


id: GO:1901855
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin.","definition_xrefs":["UniPathway:UPA00069","GOC:TermGenie","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tricarboxylic acid biosynthetic process","termid":"GO:0072351"},{"relation_name":"is_a","term_name":"5,6,7,8-tetrahydrosarcinapterin metabolic process","termid":"GO:1901853"},{"relation_name":"is_a","term_name":"tetrahydromethanopterin biosynthetic process","termid":"GO:2001118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0042559"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0042559","GO:0044281"],"is_obsolete":false,"name":"5,6,7,8-tetrahydrosarcinapterin biosynthetic process","synonyms":[{"name":"5,6,7,8-tetrahydrosarcinapterin anabolism","type":"exact"},{"name":"5,6,7,8-tetrahydrosarcinapterin biosynthesis","type":"exact"},{"name":"5,6,7,8-tetrahydrosarcinapterin formation","type":"exact"},{"name":"5,6,7,8-tetrahydrosarcinapterin synthesis","type":"exact"}],"termid":"GO:1901855"}


id: MONDO:0044778
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)","definition_xrefs":["NCIT:C7258"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Hodgkins lymphoma","termid":"MONDO:0004952"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"nodular lymphocyte predominant Hodgkin lymphoma","secondary_identifiers":["UMLS:C1334968","GARD:19079","Orphanet:86893","MEDGEN:233758","NANDO:1201067","icd11.foundation:331115338","ONCOTREE:NLPHL"],"synonyms":[{"name":"Hodgkin lymphoma nodular LP, NOS","type":"exact"},{"name":"Hodgkin lymphoma nodular lymphocyte predominant type, NOS","type":"exact"},{"name":"NLPHL","type":"exact"},{"name":"nodular lymphocyte predominant Hodgkin lymphoma","type":"exact"},{"name":"nodular lymphocyte predominant Hodgkin's lymphoma","type":"exact"},{"name":"nodular lymphocyte-predominant Hodgkin lymphoma","type":"exact"}],"termid":"MONDO:0044778","xrefs":{"Monarch":{"xref_id":"0044778"}}}


id: PR:O60121
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A stomatin-like protein 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO04040","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C16G5.07c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16G5.07c","secondary_identifiers":["UniProtKB:O60121"],"synonyms":[{"name":"Spom972h-STOML2","type":"exact"}],"termid":"PR:O60121"}


id: MONDO:0004847
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cataract with no obvious cause occurring in persons over 50 years old.","direct_ancestors":[{"relation_name":"is_a","term_name":"cataract","termid":"MONDO:0005129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"senile cataract","secondary_identifiers":["UMLS:C0036646","MEDGEN:11372","ICD9:366.1","ICD9:366.10","DOID:9669","NCIT:C35012","SCTID:39450006"],"termid":"MONDO:0004847","xrefs":{"Monarch":{"xref_id":"0004847"}}}


id: GO:0017166
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoskeletal protein binding","termid":"GO:0008092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0008092"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0008092","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"vinculin binding","termid":"GO:0017166"}


id: MONDO:0005166
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, well-circumscribed, bone-forming neoplasm predominantly composed of lamellar bone. It usually arises from the calvarial, facial, or jaw bones. It is usually asymptomatic but it may cause local swelling or obstruction of the paranasal sinuses. Asymptomatic cases have an indolent clinical course.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bone benign neoplasm","termid":"MONDO:0000631"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteoma","secondary_identifiers":["MEDGEN:18220","SCTID:302858007","MESH:D010016","HP:0100246","EFO:0002423","NCIT:C3296","UMLS:C0029440","ICDO:9180/0"],"synonyms":[{"name":"osteoma","type":"exact"},{"name":"osteoma (disease)","type":"exact"},{"name":"osteoma, benign","type":"exact"}],"termid":"MONDO:0005166","xrefs":{"Monarch":{"xref_id":"0005166"}}}


id: MONDO:0010884
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"facioscapulohumeral muscular dystrophy","termid":"MONDO:0001347"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0019303"}],"interesting_parent_ids":["MONDO:0019303","MONDO:0005336"],"is_obsolete":false,"name":"muscular dystrophy, scapulohumeral","secondary_identifiers":["MESH:C562932","GARD:15317","UMLS:C0410192","SCTID:240074006","MEDGEN:98373","OMIM:600416"],"synonyms":[{"name":"muscular dystrophy, scapulohumeral","type":"exact"}],"termid":"MONDO:0010884","xrefs":{"Monarch":{"xref_id":"0010884"}}}


id: PBO:0003034
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.1.6.1","termid":"PBO:0003034"}


id: PBO:0012541
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-regulates_o_acts_on_population_of","termid":"PBO:0012541"}


id: PBO:0054737
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2146","termid":"PBO:0054737"}


id: FYPO:0004128
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a cysteine-type peptidase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal peptidase activity","termid":"FYPO:0000666"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0001985","FYPO:0000661","FYPO:0000707","FYPO:0000654"],"is_obsolete":false,"name":"abnormal cysteine-type peptidase activity","synonyms":[{"name":"abnormal caspase activity","type":"narrow"},{"name":"abnormal cysteine protease activity","type":"exact"}],"termid":"FYPO:0004128"}


id: MONDO:0015377
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cysts and fistulae of the face and oral cavity","termid":"MONDO:0015476"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"third branchial cleft anomaly","secondary_identifiers":["SCTID:73391000119102","UMLS:C3874314","Orphanet:141030","MEDGEN:850398","GARD:19935"],"synonyms":[{"name":"third branchial cleft cyst","type":"exact"},{"name":"third branchial cleft fistula","type":"exact"}],"termid":"MONDO:0015377","xrefs":{"Monarch":{"xref_id":"0015377"}}}


id: SO:0001363
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"5_aminomethyl_2_thiouridine is a modified uridine base feature.","direct_ancestors":[{"relation_name":"is_a","term_name":"modified_uridine","termid":"SO:0001277"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"five_aminomethyl_two_thiouridine","secondary_identifiers":["RNAMOD:071"],"synonyms":[{"name":"5-aminomethyl-2-thiouridine","type":"exact"},{"name":"five aminomethyl two thiouridine","type":"exact"},{"name":"nm5s2U","type":"exact"}],"termid":"SO:0001363"}


id: GO:0071440
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of histone H3-K14 acetylation (obsolete GO:0071440)","synonyms":[{"name":"regulation of histone H3 acetylation at K14","type":"exact"},{"name":"regulation of histone H3K14 acetylation","type":"exact"}],"termid":"GO:0071440"}


id: MONDO:0012007
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"scimitar anomaly, multiple cardiac malformations, and craniofacial and central nervous system abnormalities","secondary_identifiers":["MEDGEN:331265","OMIM:608281","MESH:C564262","UMLS:C1842315"],"synonyms":[{"name":"anomalous pulmonary Venous return, multiple Cardiac malformations, and craniofacial and central nervous system abnormalities","type":"related"},{"name":"scimitar anomaly, multiple cardiac malformations, and craniofacial and central nervous system abnormalities","type":"exact"}],"termid":"MONDO:0012007","xrefs":{"Monarch":{"xref_id":"0012007"}}}


id: GO:0033412
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A triplet codon-amino acid adaptor activity that recognizes a UAG codon.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triplet codon-amino acid adaptor activity","termid":"GO:0030533"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"}],"interesting_parent_ids":["GO:0003723","GO:0060090","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"UAG codon-amino acid adaptor activity","synonyms":[{"name":"TAG codon-amino acid adaptor activity","type":"exact"}],"termid":"GO:0033412"}


id: MONDO:0019660
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pfeiffer syndrome type 2 (PS2) is a frequent and severe type of Pfeiffer syndrome (PS), characterized by cloverleaf skull, severe associated functional disorders, and hand/foot and elbow/knee abnormalities.","definition_xrefs":["Orphanet:93259"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Pfeiffer syndrome","termid":"MONDO:0007043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"Pfeiffer syndrome type 2","secondary_identifiers":["UMLS:C5438849","icd11.foundation:531949642","GARD:16808","MEDGEN:1761826"],"termid":"MONDO:0019660","xrefs":{"Monarch":{"xref_id":"0019660"}}}


id: PBO:0065061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1","termid":"PBO:0065061"}


id: PBO:0034423
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-condition_(obsolete_condition)","termid":"PBO:0034423"}


id: PBO:0090793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome assembly chaperone Pac3","termid":"PBO:0090793"}


id: GO:0071107
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.","definition_xrefs":["GOC:mah","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to hormone","termid":"GO:0009725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to parathyroid hormone","synonyms":[{"name":"response to parathyroid hormone stimulus","type":"exact"}],"termid":"GO:0071107"}


id: FYPO:0004278
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of uracil DNA N-glycosylase activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal uracil DNA N-glycosylase activity","termid":"FYPO:0004277"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000654","FYPO:0000707","FYPO:0000661","FYPO:0001985"],"is_obsolete":false,"name":"decreased uracil DNA N-glycosylase activity","synonyms":[{"name":"reduced uracil DNA N-glycosylase activity","type":"exact"}],"termid":"FYPO:0004278"}


id: PBO:0067625
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 797, pseudogene","termid":"PBO:0067625"}


id: FYPO:0003971
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which a spore germinates to produce a cell of that undergoes two or more rounds of cell division in which cells do not completely separate upon cytokinesis, form septa that are thicker than normal, and then die.","definition_xrefs":["PomBase:mah","PMID:9046095","PomBase:vw"],"direct_ancestors":[{"relation_name":"has_part","term_name":"increased septum thickness","termid":"FYPO:0001406"},{"relation_name":"has_part","term_name":"abnormal cell separation after cytokinesis resulting in septated cell","termid":"FYPO:0001972"},{"relation_name":"is_a","term_name":"abnormal cell separation after cytokinesis","termid":"FYPO:0000164"},{"relation_name":"is_a","term_name":"increased septum thickness","termid":"FYPO:0001406"},{"relation_name":"is_a","term_name":"inviable after spore germination, multiple cell divisions, with abnormal septation","termid":"FYPO:0006878"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0005447","FYPO:0000004","FYPO:0000002","FYPO:0000032","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"inviable after spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness","synonyms":[{"name":"inviable after spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and thick septa","type":"exact"},{"name":"inviable following spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness","type":"exact"},{"name":"inviable germinated spore, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness","type":"exact"},{"name":"lethal after spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness","type":"exact"}],"termid":"FYPO:0003971"}


id: MONDO:0020525
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Transient neonatal diabetes mellitus (TNDM) is a genetically heterogeneous form of neonatal diabetes (NDM) characterized by hyperglycemia presenting in the neonatal period that remits during infancy but recurs in later life in most patients.","definition_xrefs":["Orphanet:99886"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neonatal diabetes mellitus","termid":"MONDO:0016391"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005015"}],"interesting_parent_ids":["MONDO:0005015","MONDO:0004335","MONDO:0005066"],"is_obsolete":false,"name":"transient neonatal diabetes mellitus","secondary_identifiers":["icd11.foundation:1596856936","UMLS:C0342273","MEDGEN:449530","DOID:0060334","HP:0008255","NCIT:C114899","SCTID:237603002"],"synonyms":[{"name":"TNDM","type":"exact"},{"name":"chromosome 6-associated transient diabetes mellitus","type":"related"},{"name":"diabetes mellitus, 6q24-related transient neonatal","type":"related"},{"name":"diabetes mellitus, transient neonatal","type":"related"},{"name":"transient neonatal diabetes mellitus","type":"exact"},{"name":"transient neonatal diabetes mellitus (disease)","type":"exact"}],"termid":"MONDO:0020525","xrefs":{"Monarch":{"xref_id":"0020525"}}}


id: PBO:0058890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 10527","termid":"PBO:0058890"}


id: PBO:0062787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ORC1 pseudogene 1","termid":"PBO:0062787"}


id: PBO:0048384
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase activating Rap/RanGAP domain like 3","termid":"PBO:0048384"}


id: FYPO:0009041
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 2,2′-dipyridyl than normal.","definition_xrefs":["PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000003","FYPO:0002682","FYPO:0001985","FYPO:0000139"],"is_obsolete":false,"name":"resistance to 2,2′-dipyridyl","synonyms":[{"name":"resistance to 2,2′-dipyridyl during mitotic cell cycle","type":"related"},{"name":"resistance to 2,2′-dipyridyl during vegetative growth","type":"exact"},{"name":"resistant to 2,2′-dipyridyl","type":"exact"}],"termid":"FYPO:0009041"}


id: MONDO:0019751
data:
  {"annotated_genes":["SJAG_05239","SJAG_00400","SJAG_02039","SJAG_04541","SJAG_03596","SJAG_03805","SJAG_00853","SJAG_01474","SJAG_04118","SJAG_04865","SJAG_00321","SJAG_02763","SJAG_01884","SJAG_04969","SJAG_03151","SJAG_04077","SJAG_04380","SJAG_04290","SJAG_04569"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85117],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012429"},{"annotations":[84948],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012471"},{"annotations":[84951],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012472"},{"annotations":[85037],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014007"},{"annotations":[87045],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014629"},{"annotations":[87000],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013944"},{"annotations":[85799],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007483"},{"annotations":[86418],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013766"},{"annotations":[86521,86522],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009849"},{"annotations":[85664],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012316"},{"annotations":[84846,84845],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012481"},{"annotations":[86517],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054698"},{"annotations":[86328],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054700"},{"annotations":[85201,85200],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054699"},{"annotations":[84901,84900],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011462"},{"annotations":[86202],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024541"},{"annotations":[86053],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013818"},{"annotations":[85670],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0026777"},{"annotations":[85419],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010523"}]},"cv_name":"mondo","definition":"A group of disorders of the innate immune system characterized by attacks of seemingly unprovoked inflammation without significant levels of either autoantibodies or autoreactive T cells more characteristic of autoimmune disease.","definition_xrefs":["PMID:23827249","NCIT:C119050"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"rheumatic disorder","termid":"MONDO:0005554"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00321":null,"SJAG_00400":null,"SJAG_00853":null,"SJAG_01474":null,"SJAG_01884":null,"SJAG_02039":null,"SJAG_02763":null,"SJAG_03151":null,"SJAG_03596":null,"SJAG_03805":null,"SJAG_04077":null,"SJAG_04118":null,"SJAG_04290":null,"SJAG_04380":null,"SJAG_04541":null,"SJAG_04569":null,"SJAG_04865":null,"SJAG_04969":null,"SJAG_05239":null},"genotype_count":0,"is_obsolete":false,"name":"autoinflammatory syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NANDO:2100156","GARD:19234","MedDRA:10072220","MEDGEN:855741","Orphanet:93665","UMLS:C3890737","ICD10CM:M04-M04"],"termid":"MONDO:0019751","terms_by_termid":{"MONDO:0007483":null,"MONDO:0009849":null,"MONDO:0010523":null,"MONDO:0011462":null,"MONDO:0012316":null,"MONDO:0012429":null,"MONDO:0012471":null,"MONDO:0012472":null,"MONDO:0012481":null,"MONDO:0013766":null,"MONDO:0013818":null,"MONDO:0013944":null,"MONDO:0014007":null,"MONDO:0014629":null,"MONDO:0024541":null,"MONDO:0026777":null,"MONDO:0054698":null,"MONDO:0054699":null,"MONDO:0054700":null},"xrefs":{"Monarch":{"xref_id":"0019751"}}}


id: SO:0002001
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A segment of non-homology between a and alpha mating alleles, found at all three mating loci (HML, MAT, and HMR), has two forms (Ya and Yalpha).","definition_xrefs":["SGD:jd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mating_type_region_motif","termid":"SO:0001999"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Y_region","synonyms":[{"name":"Y-region","type":"exact"}],"termid":"SO:0002001"}


id: PR:Q9UT57
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A cytosolic Fe-S cluster assembly factor NUBP2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR23264:SF9","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytosolic Fe-S cluster assembly factor SPAC806.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC806.02c","secondary_identifiers":["UniProtKB:Q9UT57"],"synonyms":[{"name":"Spom972h-NUBP2","type":"exact"}],"termid":"PR:Q9UT57"}


id: PBO:0071318
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L27a pseudogene 2","termid":"PBO:0071318"}


id: PBO:0030478
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_glutamine_level","termid":"PBO:0030478"}


id: GO:1904490
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of mitochondrial unfolded protein response.","definition_xrefs":["GOC:TermGenie","GOC:kmv","PMID:25961505","GO_REF:0000063"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter (obsolete GO:1904490)","synonyms":[{"name":"negative regulation of mitochondrial unfolded protein response by down regulation of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mitochondrial unfolded protein response by down regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mitochondrial unfolded protein response by down-regulation of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mitochondrial unfolded protein response by down-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mitochondrial unfolded protein response by downregulation of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mitochondrial unfolded protein response by downregulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mitochondrial unfolded protein response by inhibition of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mitochondrial unfolded protein response by inhibition of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mitochondrial unfolded protein response by negative regulation of gene-specific transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mitochondrial unfolded protein response by negative regulation of global transcription from Pol II promoter","type":"related"},{"name":"negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from Pol II promoter","type":"exact"},{"name":"negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter, global","type":"related"},{"name":"negative regulation of mtUPR by down regulation of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mtUPR by down regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mtUPR by down-regulation of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mtUPR by down-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mtUPR by downregulation of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mtUPR by downregulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mtUPR by inhibition of global transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mtUPR by inhibition of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mtUPR by negative regulation of gene-specific transcription from RNA polymerase II promoter","type":"related"},{"name":"negative regulation of mtUPR by negative regulation of global transcription from Pol II promoter","type":"related"},{"name":"negative regulation of mtUPR by negative regulation of transcription from Pol II promoter","type":"exact"},{"name":"negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter, global","type":"related"}],"termid":"GO:1904490"}


id: GO:0047425
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H2O + H+ = 2,5-dioxopentanoate + NH4.","definition_xrefs":["EC:3.5.4.22","RHEA:10560"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines","termid":"GO:0016814"},{"relation_name":"is_a","term_name":"deaminase activity","termid":"GO:0019239"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0016810","GO:0003674"],"is_obsolete":false,"name":"1-pyrroline-4-hydroxy-2-carboxylate deaminase activity","secondary_identifiers":["KEGG_REACTION:R02280","MetaCyc:3.5.4.22-RXN"],"synonyms":[{"name":"1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing)","type":"related"},{"name":"HPC deaminase activity","type":"related"}],"termid":"GO:0047425"}


id: GO:0009851
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.","definition_xrefs":["GOC:lm","GOC:lr","ISBN:0122146743"],"direct_ancestors":[{"relation_name":"is_a","term_name":"auxin metabolic process","termid":"GO:0009850"},{"relation_name":"is_a","term_name":"hormone biosynthetic process","termid":"GO:0042446"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"auxin biosynthetic process","synonyms":[{"name":"auxin anabolism","type":"exact"},{"name":"auxin biosynthesis","type":"exact"},{"name":"auxin formation","type":"exact"},{"name":"auxin synthesis","type":"exact"}],"termid":"GO:0009851"}


id: GO:0110003
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.","definition_xrefs":["GOC:vw","PMID:23074192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of tRNA methylation","termid":"GO:0110002"},{"relation_name":"regulates","term_name":"tRNA C5-cytosine methylation","termid":"GO:0002946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006399"}],"interesting_parent_ids":["GO:0010467","GO:0006399","GO:0008150"],"is_obsolete":false,"name":"regulation of tRNA C5-cytosine methylation","termid":"GO:0110003"}


id: GO:0052845
data:
  {"annotated_genes":["SJAG_04870","SJAG_01154"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[88485,104963],"is_not":false,"summary":null,"term":"GO:0052845"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + H+.","definition_xrefs":["RHEA:22384","PMID:10827188","PMID:11502751"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inositol diphosphate pentakisphosphate diphosphatase activity","termid":"GO:0052842"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01154":null,"SJAG_04870":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["KEGG_REACTION:R05779","MetaCyc:RXN-10964"],"termid":"GO:0052845","terms_by_termid":{"GO:0052845":null}}


id: MONDO:0002523
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The mucinoses are a diverse group of disorders which have in common the deposition of basophilic, finely granular and stringy material (mucin) in the connective tissues of the dermis (dermal mucinoses), in the pilosebaceous follicles (follicular mucinoses), or in the epidermis and tumors derived therefrom (epithelial mucinoses).","definition_xrefs":["ISBN-13:978-0-7020-3485-5"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"connective tissue disorder","termid":"MONDO:0003900"},{"relation_name":"is_a","term_name":"skin disorder","termid":"MONDO:0005093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"cutaneous mucinosis","secondary_identifiers":["MESH:D017520","UMLS:C0162855","icd11.foundation:2018255084","SCTID:402721001","DOID:3141","ICD9:701.8","MEDGEN:56520"],"synonyms":[{"name":"mucinoses","type":"related"},{"name":"mucinosis","type":"exact"},{"name":"mucinosis affecting the skin","type":"exact"}],"termid":"MONDO:0002523","xrefs":{"Monarch":{"xref_id":"0002523"}}}


id: GO:0051648
data:
  {"annotated_genes":["SJAG_03011","SJAG_02651","SJAG_00594","SJAG_01925","SJAG_02166","SJAG_04391","SJAG_02320","SJAG_03938","SJAG_04044","SJAG_04960","SJAG_03864","SJAG_03357","SJAG_03268","SJAG_03005"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117485,71084],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0048205"},{"annotations":[118177],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0099022"},{"annotations":[65870,90511,113900,99311,101675,117470,60170,88384],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0090522"},{"annotations":[115925],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030050"},{"annotations":[104633,104302],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0047496"}]},"cv_name":"biological_process","definition":"Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle localization","termid":"GO:0051640"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00594":null,"SJAG_01925":null,"SJAG_02166":null,"SJAG_02320":null,"SJAG_02651":null,"SJAG_03005":null,"SJAG_03011":null,"SJAG_03268":null,"SJAG_03357":null,"SJAG_03864":null,"SJAG_03938":null,"SJAG_04044":null,"SJAG_04391":null,"SJAG_04960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"vesicle localization","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"cytoplasmic vesicle localization","type":"exact"},{"name":"establishment and maintenance of vesicle localization","type":"exact"},{"name":"vesicle localisation","type":"exact"}],"termid":"GO:0051648","terms_by_termid":{"GO:0030050":null,"GO:0047496":null,"GO:0048205":null,"GO:0090522":null,"GO:0099022":null}}


id: PBO:0044877
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DENN domain containing 5B","termid":"PBO:0044877"}


id: GO:0060679
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a ureteric bud splits into three units at its end.","definition_xrefs":["GOC:dph","PMID:16916378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"morphogenesis of an epithelium","termid":"GO:0002009"},{"relation_name":"part_of","term_name":"branching involved in ureteric bud morphogenesis","termid":"GO:0001658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"trifid subdivision of terminal units involved in ureteric bud branching","termid":"GO:0060679"}


id: GO:0047099
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose.","definition_xrefs":["EC:1.17.1.1","MetaCyc:1.17.1.1-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor","termid":"GO:0016726"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"CDP-4-dehydro-6-deoxyglucose reductase activity","synonyms":[{"name":"CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity","type":"related"},{"name":"CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity","type":"related"},{"name":"CDP-4-keto-6-deoxyglucose reductase activity","type":"related"},{"name":"CDP-4-keto-deoxy-glucose reductase activity","type":"related"},{"name":"NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity","type":"related"},{"name":"cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity","type":"related"},{"name":"cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity","type":"related"}],"termid":"GO:0047099"}


id: PBO:0043985
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"colony stimulating factor 2","termid":"PBO:0043985"}


id: GO:0047258
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: sphingosine + UDP-D-galactose = H+ + psychosine + UDP.","definition_xrefs":["EC:2.4.1.23","RHEA:19485"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-galactosyltransferase activity","termid":"GO:0035250"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"sphingosine beta-galactosyltransferase activity","secondary_identifiers":["KEGG_REACTION:R01928","MetaCyc:2.4.1.23-RXN"],"synonyms":[{"name":"UDP-galactose:sphingosine 1-beta-galactotransferase activity","type":"related"},{"name":"UDPgalactose:sphingosine 1-beta-galactotransferase activity","type":"related"},{"name":"UDPgalactose:sphingosine O-galactosyl transferase activity","type":"related"},{"name":"galactosyl-sphingosine transferase activity","type":"related"},{"name":"psychosine-UDP galactosyltransferase activity","type":"related"},{"name":"psychosine-uridine diphosphate galactosyltransferase activity","type":"related"},{"name":"uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity","type":"related"}],"termid":"GO:0047258"}


id: MONDO:0013259
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Oguchi disease in which the cause of the disease is a mutation in the GRK1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete hereditary night blindness (obsolete MONDO:0004587)","termid":"MONDO:0004587"},{"relation_name":"is_a","term_name":"Oguchi disease","termid":"MONDO:0019152"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"Oguchi disease-2","secondary_identifiers":["OMIM:613411","MEDGEN:462028","UMLS:C3150678","GARD:15660","DOID:0110713"],"synonyms":[{"name":"CSNBO2","type":"exact"},{"name":"GRK1 Oguchi disease","type":"exact"},{"name":"Oguchi disease 2","type":"related"},{"name":"Oguchi disease caused by mutation in GRK1","type":"exact"},{"name":"Oguchi disease type 2","type":"exact"},{"name":"congenital stationary night blindness Oguchi type 2","type":"exact"},{"name":"night blindness, congenital stationary, Oguchi type 2","type":"related"}],"termid":"MONDO:0013259","xrefs":{"Monarch":{"xref_id":"0013259"}}}


id: GO:0050054
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 vanillin.","definition_xrefs":["RHEA:21340","EC:1.13.11.43"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","termid":"GO:0016702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"lignostilbene alpha beta-dioxygenase activity","secondary_identifiers":["MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN","KEGG_REACTION:R00043"],"synonyms":[{"name":"1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)","type":"related"},{"name":"lignostilbene ab-dioxygenase activity","type":"exact"},{"name":"lignostilbene alphabeta-dioxygenase activity","type":"related"}],"termid":"GO:0050054"}


id: PBO:0080128
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vesicle associated membrane protein 7","termid":"PBO:0080128"}


id: PBO:0053510
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 498","termid":"PBO:0053510"}


id: PBO:0079351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TUB bipartite transcription factor","termid":"PBO:0079351"}


id: GO:0004799
data:
  {"annotated_genes":["SJAG_04627"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[79132],"is_not":false,"summary":null,"term":"GO:0004799"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.","definition_xrefs":["EC:2.1.1.45","RHEA:12104"],"direct_ancestors":[{"relation_name":"is_a","term_name":"5,10-methylenetetrahydrofolate-dependent methyltransferase activity","termid":"GO:0042083"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04627":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0016741","GO:0003824"],"is_obsolete":false,"name":"thymidylate synthase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R02101","MetaCyc:THYMIDYLATESYN-RXN","Reactome:R-HSA-73605"],"synonyms":[{"name":"5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity","type":"related"},{"name":"TMP synthetase activity","type":"related"},{"name":"dTMP synthase activity","type":"related"},{"name":"methylenetetrahydrofolate:dUMP C-methyltransferase activity","type":"related"},{"name":"thymidylate synthetase activity","type":"related"}],"termid":"GO:0004799","terms_by_termid":{"GO:0004799":null}}


id: GO:0030149
data:
  {"annotated_genes":["SJAG_00519","SJAG_01219"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89591,108574],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046521"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).","definition_xrefs":["ISBN:0198506732","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sphingolipid metabolic process","termid":"GO:0006665"},{"relation_name":"is_a","term_name":"membrane lipid catabolic process","termid":"GO:0046466"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00519":null,"SJAG_01219":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"sphingolipid catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-9845614"],"synonyms":[{"name":"sphingolipid breakdown","type":"exact"},{"name":"sphingolipid catabolism","type":"exact"},{"name":"sphingolipid degradation","type":"exact"}],"termid":"GO:0030149","terms_by_termid":{"GO:0046521":null}}


id: GO:0070939
data:
  {"annotated_genes":["SJAG_04956","SJAG_01166"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[76402,99777],"is_not":false,"summary":null,"term":"GO:0070939"}]},"cv_name":"cellular_component","definition":"A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.","definition_xrefs":["GOC:mah","PMID:19151722","PMID:21550981","GOC:jh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle tethering complex","termid":"GO:0099023"},{"relation_name":"is_a","term_name":"endoplasmic reticulum protein-containing complex","termid":"GO:0140534"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01166":null,"SJAG_04956":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005783"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005783","GO:0005737"],"is_obsolete":false,"name":"Dsl1/NZR complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"CATCHR family complex","type":"broad"},{"name":"Dsl1p complex","type":"exact"},{"name":"NZR complex","type":"exact"}],"termid":"GO:0070939","terms_by_termid":{"GO:0070939":null}}


id: FYPO:0005434
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the occurrence of meiotic recombination is decreased both at recombination hotspots and elsewhere in the genome.","definition_xrefs":["PMID:12019258","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased meiotic recombination","termid":"FYPO:0000485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0000293","FYPO:0000631","FYPO:0005447"],"is_obsolete":false,"name":"globally decreased meiotic recombination","synonyms":[{"name":"globally reduced meiotic recombination","type":"exact"}],"termid":"FYPO:0005434"}


id: GO:0060595
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.","definition_xrefs":["PMID:16168142","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fibroblast growth factor receptor signaling pathway","termid":"GO:0008543"},{"relation_name":"part_of","term_name":"mammary gland specification","termid":"GO:0060594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"fibroblast growth factor receptor signaling pathway involved in mammary gland specification","synonyms":[{"name":"fibroblast growth factor receptor signalling pathway involved in mammary gland specification","type":"exact"}],"termid":"GO:0060595"}


id: FYPO:0000301
data:
  {"alleles_by_uniquename":{"SJAG_00514:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00514","name":"scd1delta","uniquename":"SJAG_00514:allele-1"},"SJAG_00601:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00601","name":"rip1delta","uniquename":"SJAG_00601:allele-1"},"SJAG_00993:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00993","name":"byr1delta","uniquename":"SJAG_00993:allele-1"},"SJAG_01355:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01355","name":"cox6delta","uniquename":"SJAG_01355:allele-1"},"SJAG_01718:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01718","name":"byr2delta","uniquename":"SJAG_01718:allele-1"},"SJAG_01794:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01794","name":"scd2delta","uniquename":"SJAG_01794:allele-1"},"SJAG_02379:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02379","name":"gap1delta","uniquename":"SJAG_02379:allele-1"},"SJAG_02486:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02486","name":"ste6delta","uniquename":"SJAG_02486:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"},"SJAG_02923:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02923","name":"spk1delta","uniquename":"SJAG_02923:allele-1"},"SJAG_03453:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03453","name":"ras1delta","uniquename":"SJAG_03453:allele-1"},"SJAG_04009:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04009","name":"ste11delta","uniquename":"SJAG_04009:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[119149,119146],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000760"},{"annotations":[118855,118856,118866,118849,118879,119048,118881,118863,118865,118860],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000280"}]},"cv_name":"fission_yeast_phenotype","definition":"A biological process phenotype that affects conjugation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological process 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phenotype","references_by_uniquename":{"PMID:29566183":null,"PMID:31150379":null,"PMID:37164017":null},"single_locus_annotated_genes":["SJAG_00993","SJAG_00601","SJAG_01718","SJAG_01355","SJAG_02923","SJAG_02486","SJAG_02592","SJAG_02379","SJAG_01794","SJAG_03453","SJAG_04009","SJAG_00514"],"single_locus_genotype_uniquenames":["gap1delta","ras1delta","cox6delta","rip1delta","byr2delta","byr1delta","spk1delta","scd2delta","ste11delta","scd1delta","sty1delta","ste6delta"],"synonyms":[{"name":"conjugation phenotype","type":"exact"},{"name":"fission yeast mating phenotype","type":"exact"}],"termid":"FYPO:0000301","terms_by_termid":{"FYECO:0000015":null,"FYECO:0000272":null,"FYPO:0000280":null,"FYPO:0000760":null,"FYPO_EXT:0000001":null}}


id: MONDO:0022504
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis spinal muscular atrophy","termid":"MONDO:0022504","xrefs":{"Monarch":{"xref_id":"0022504"}}}


id: GO:0000957
data:
  {"annotated_genes":["SJAG_02383","SJAG_01948","SJAG_02526"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90142,90545,113628],"is_not":false,"summary":null,"term":"GO:0000957"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.","definition_xrefs":["GOC:mah","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial RNA metabolic process","termid":"GO:0000959"},{"relation_name":"is_a","term_name":"RNA catabolic process","termid":"GO:0006401"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01948":null,"SJAG_02383":null,"SJAG_02526":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mitochondrial RNA catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-9836573"],"termid":"GO:0000957","terms_by_termid":{"GO:0000957":null}}


id: SO:0000511
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Genomic DNA of immunoglobulin/T-cell receptor gene in germline configuration including at least one J-gene and one C-gene.","direct_ancestors":[{"relation_name":"has_part","term_name":"J_gene_segment","termid":"SO:0000470"},{"relation_name":"has_part","term_name":"C_gene_segment","termid":"SO:0000478"},{"relation_name":"is_a","term_name":"vertebrate_immunoglobulin_T_cell_receptor_gene_cluster","termid":"SO:0000482"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"J_C_cluster","synonyms":[{"name":"J C cluster","type":"exact"},{"name":"J-C-CLUSTER","type":"exact"}],"termid":"SO:0000511"}


id: PBO:0084379
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Low-affinity amino acid permease; may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition","termid":"PBO:0084379"}


id: GO:0050305
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H2O + NAD+ = glycine + H+ + NADH + pyruvate.","definition_xrefs":["EC:1.5.1.22","RHEA:14061"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"strombine dehydrogenase activity","secondary_identifiers":["MetaCyc:STROMBINE-DEHYDROGENASE-RXN","KEGG_REACTION:R00368"],"synonyms":[{"name":"N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity","type":"related"},{"name":"N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)","type":"related"},{"name":"strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity","type":"related"}],"termid":"GO:0050305"}


id: GO:0052838
data:
  {"annotated_genes":["SJAG_00827"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73506],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052837"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfur compound metabolic process","termid":"GO:0006790"},{"relation_name":"is_a","term_name":"oxazole or thiazole metabolic process","termid":"GO:0046484"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00827":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006790"}],"interesting_parent_ids":["GO:0006790","GO:0008150"],"is_obsolete":false,"name":"thiazole metabolic process","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"thiazole metabolism","type":"exact"}],"termid":"GO:0052838","terms_by_termid":{"GO:0052837":null}}


id: PBO:0082048
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; yeast null mutant can be functionally complemented by human FTSJ1, mutations in which have been implicated in nonsyndromic X-linked intellectual disability (NSXLID)","termid":"PBO:0082048"}


id: PBO:0032709
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_error-free_translesion_synthesis_of_pyrimidine-pyrimidone_6-4_photoproducts","termid":"PBO:0032709"}


id: PBO:0064459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pogo transposable element derived with ZNF domain","termid":"PBO:0064459"}


id: PBO:0000729
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-saccharopine oxidase","termid":"PBO:0000729"}


id: GO:1902269
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.","definition_xrefs":["GOC:TermGenie","PMID:23755272"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transmembrane transport","termid":"GO:0034764"},{"relation_name":"is_a","term_name":"regulation of polyamine transmembrane transport","termid":"GO:1902267"},{"relation_name":"positively_regulates","term_name":"polyamine transmembrane transport","termid":"GO:1902047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0008150","GO:0055085","GO:0006810"],"is_obsolete":false,"name":"positive regulation of polyamine transmembrane transport","synonyms":[{"name":"activation of polyamine transmembrane transport","type":"narrow"},{"name":"up regulation of polyamine transmembrane transport","type":"exact"},{"name":"up-regulation of polyamine transmembrane transport","type":"exact"},{"name":"upregulation of polyamine transmembrane transport","type":"exact"}],"termid":"GO:1902269"}


id: GO:0015254
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the energy-independent facilitated diffusion of glycerol through a transmembrane aqueous pore or channel.","definition_xrefs":["GOC:mtg_transport","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycerol transmembrane transporter activity","termid":"GO:0015168"},{"relation_name":"is_a","term_name":"channel activity","termid":"GO:0015267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"glycerol channel activity","secondary_identifiers":["Reactome:R-HSA-432074","Reactome:R-HSA-507871","Reactome:R-HSA-507869","MetaCyc:TRANS-RXN-131","Reactome:R-HSA-432049"],"termid":"GO:0015254"}


id: PBO:0074445
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small integral membrane protein 46","termid":"PBO:0074445"}


id: GO:0031314
data:
  {"annotated_genes":["SJAG_01249","SJAG_00852","SJAG_04000","SJAG_00721","SJAG_01043","SJAG_05398","SJAG_00230","SJAG_00576","SJAG_04642","SJAG_00933","SJAG_03456","SJAG_03563"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[60627,62081,63759,64960,90641,101034,105964,106618,107916,109258],"is_not":false,"summary":null,"term":"GO:0031314"},{"annotations":[100211,103515],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0099616"}]},"cv_name":"cellular_component","definition":"The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.","definition_xrefs":["GOC:dos","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extrinsic component of organelle membrane","termid":"GO:0031312"},{"relation_name":"part_of","term_name":"mitochondrial inner membrane","termid":"GO:0005743"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00230":null,"SJAG_00576":null,"SJAG_00721":null,"SJAG_00852":null,"SJAG_00933":null,"SJAG_01043":null,"SJAG_01249":null,"SJAG_03456":null,"SJAG_03563":null,"SJAG_04000":null,"SJAG_04642":null,"SJAG_05398":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005739"}],"interesting_parent_ids":["GO:0005575","GO:0005739","GO:0005737"],"is_obsolete":false,"name":"extrinsic component of mitochondrial inner membrane","references_by_uniquename":{"GO_REF:0000104":null,"GO_REF:0000107":null},"synonyms":[{"name":"extrinsic to mitochondrial inner membrane","type":"narrow"}],"termid":"GO:0031314","terms_by_termid":{"GO:0031314":null,"GO:0099616":null}}


id: PBO:0003631
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NEDD8 protease Nep2","termid":"PBO:0003631"}


id: PBO:0040739
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCR pseudogene 5","termid":"PBO:0040739"}


id: GO:0005808
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete Golgi-plasma membrane transport vesicle (obsolete GO:0005808)","synonyms":[{"name":"Golgi-plasma membrane transport vesicle","type":"exact"}],"termid":"GO:0005808"}


id: GO:0009158
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.","definition_xrefs":["GOC:go_curators","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside monophosphate catabolic process","termid":"GO:0009125"},{"relation_name":"is_a","term_name":"ribonucleoside monophosphate metabolic process","termid":"GO:0009161"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0055086"],"is_obsolete":false,"name":"ribonucleoside monophosphate catabolic process","synonyms":[{"name":"ribonucleoside monophosphate breakdown","type":"exact"},{"name":"ribonucleoside monophosphate catabolism","type":"exact"},{"name":"ribonucleoside monophosphate degradation","type":"exact"}],"termid":"GO:0009158"}


id: GO:0052821
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site.","definition_xrefs":["PMID:16468998","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alkylbase DNA N-glycosylase activity","termid":"GO:0003905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140097","GO:0016787","GO:0003824","GO:0016798","GO:0003674"],"is_obsolete":false,"name":"DNA-7-methyladenine glycosylase activity","termid":"GO:0052821"}


id: PATO:0000405
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape quality inhering in a bearer by virtue of the bearer's having parallel chains in undulate fashion on the border.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"shape","termid":"PATO:0000052"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"curled","termid":"PATO:0000405"}


id: PBO:0049034
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 21","termid":"PBO:0049034"}


id: MONDO:0013095
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"glioma susceptibility","termid":"MONDO:0100242"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glioma susceptibility 6","secondary_identifiers":["UMLS:C2751639","OMIM:613031","MEDGEN:414429"],"synonyms":[{"name":"GLM6","type":"exact"},{"name":"glioma susceptibility 6","type":"exact"}],"termid":"MONDO:0013095","xrefs":{"Monarch":{"xref_id":"0013095"}}}


id: PBO:0048848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gonadotropin releasing hormone 1","termid":"PBO:0048848"}


id: PBO:0064461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA polymerase alpha 2, accessory subunit","termid":"PBO:0064461"}


id: PBO:0017067
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Mug123","termid":"PBO:0017067"}


id: GO:1903850
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cristae formation.","definition_xrefs":["GO_REF:0000058","GOC:pad","GOC:PARL","GOC:TermGenie","PMID:19279012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mitochondrion organization","termid":"GO:0010821"},{"relation_name":"regulates","term_name":"cristae formation","termid":"GO:0042407"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007005"},{"rel_name":"regulates","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0008150","GO:0007005"],"is_obsolete":false,"name":"regulation of cristae formation","termid":"GO:1903850"}


id: PR:Q9UUE1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A pyruvate carboxylase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyruvate carboxylase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC17G9.11c","secondary_identifiers":["UniProtKB:Q9UUE1"],"synonyms":[{"name":"PCB (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPBC17G9.11c","type":"related"},{"name":"Spom972h-PC","type":"exact"},{"name":"pyruvic carboxylase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UUE1"}


id: PBO:0000805
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III complex subunit Rpc11","termid":"PBO:0000805"}


id: PBO:0004349
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"6.3.4.15","termid":"PBO:0004349"}


id: MONDO:0018529
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete qualitative or quantitative defects of Torsin-1A-interacting protein 1 (obsolete MONDO:0018529)","secondary_identifiers":["Orphanet:424925"],"synonyms":[{"name":"qualitative or quantitative defects of Torsin-1A-interacting protein type 1","type":"exact"}],"termid":"MONDO:0018529","xrefs":{"Monarch":{"xref_id":"0018529"}}}


id: GO:0009770
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.","definition_xrefs":["ISBN:0716731363","ISBN:0816017360","GOC:jid"],"gene_count":0,"genotype_count":0,"name":"obsolete primary charge separation in photosystem I (obsolete GO:0009770)","termid":"GO:0009770"}


id: PBO:0055868
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat protein 1","termid":"PBO:0055868"}


id: PBO:0109083
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lncRNA induced by TGF-beta and antagonizes TGF-beta signaling 1","termid":"PBO:0109083"}


id: PBO:0075171
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNRPE pseudogene 1","termid":"PBO:0075171"}


id: PBO:0086924
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pyrimidine nucleotidase; responsible for production of nicotinamide riboside and nicotinic acid riboside; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives; SDT1 has a paralog, PHM8, that arose from the whole genome duplication","termid":"PBO:0086924"}


id: MONDO:0007857
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Keratosis palmaris et plantaris-clinodactyly syndrome is characterized by the association of palmoplantar keratosis with clinodactyly of the fifth finger. Less than 20 cases have been described in the literature so far, and the majority of reported patients were of Mexican origin. Transmission is autosomal dominant.","definition_xrefs":["Orphanet:86919"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diffuse palmoplantar keratoderma","termid":"MONDO:0017666"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"keratosis palmaris et plantaris-clinodactyly syndrome","secondary_identifiers":["OMIM:148520","MESH:C563646","MEDGEN:320656","GARD:16766","UMLS:C1835663"],"synonyms":[{"name":"keratosis palmaris ET plantaris with clinodactyly","type":"related"},{"name":"palmoplantar keratoderma-clinodactyly syndrome","type":"exact"}],"termid":"MONDO:0007857","xrefs":{"Monarch":{"xref_id":"0007857"}}}


id: MONDO:1012108
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hypertrophic neuropathy, non-human animal","termid":"MONDO:1011844"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypertrophic neuropathy, dog","secondary_identifiers":["OMIA:000518-9615"],"termid":"MONDO:1012108","xrefs":{"Monarch":{"xref_id":"1012108"}}}


id: PBO:0072076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S12 pseudogene 6","termid":"PBO:0072076"}


id: GO:0002782
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated release of an antifungal peptide from a cell or a tissue.","definition_xrefs":["PMID:11807545","PMID:15638771","ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antimicrobial peptide secretion","termid":"GO:0002776"},{"relation_name":"part_of","term_name":"antifungal peptide production","termid":"GO:0002781"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0010467","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"antifungal peptide secretion","termid":"GO:0002782"}


id: SO:0100002
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region that is involved a contact with another molecule.","definition_xrefs":["EBIBS:GAR"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biochemical_region_of_peptide","termid":"SO:0100001"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"molecular_contact_region","synonyms":[{"name":"molecular contact region","type":"related"}],"termid":"SO:0100002"}


id: GO:0045328
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester.","definition_xrefs":["RESID:AA0324","GOC:cjm"],"gene_count":0,"genotype_count":0,"name":"obsolete cytochrome P450 4A1-heme linkage (obsolete GO:0045328)","synonyms":[{"name":"cytochrome P450 4A1-haem linkage","type":"exact"}],"termid":"GO:0045328"}


id: GO:0003843
data:
  {"annotated_genes":["SJAG_01288","SJAG_03587","SJAG_00876","SJAG_02222","SJAG_05285"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74562,75635,79853,112909],"is_not":false,"summary":null,"term":"GO:0003843"},{"annotations":[115565],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140752"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1).","definition_xrefs":["EC:2.4.1.34"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00876":null,"SJAG_01288":null,"SJAG_02222":null,"SJAG_03587":null,"SJAG_05285":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"1,3-beta-D-glucan synthase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["RHEA:21476","MetaCyc:13-BETA-GLUCAN-SYNTHASE-RXN","GO:0009981"],"synonyms":[{"name":"(1,3)-beta-glucan (callose) synthase activity","type":"related"},{"name":"1,3-beta-D-glucan synthetase activity","type":"related"},{"name":"1,3-beta-D-glucan-UDP glucosyltransferase activity","type":"related"},{"name":"1,3-beta-glucan synthase activity","type":"related"},{"name":"1,3-beta-glucan-uridine diphosphoglucosyltransferase activity","type":"related"},{"name":"GS-II","type":"related"},{"name":"UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity","type":"related"},{"name":"UDP-glucose-1,3-beta-glucan glucosyltransferase activity","type":"related"},{"name":"UDP-glucose-beta-glucan glucosyltransferase activity","type":"related"},{"name":"UDP-glucose:(1,3)beta-glucan synthase activity","type":"related"},{"name":"UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity","type":"related"},{"name":"UDPglucose-1,3-beta-D-glucan glucosyltransferase activity","type":"related"},{"name":"UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity","type":"related"},{"name":"beta-1,3-glucan synthase activity","type":"exact"},{"name":"beta-1,3-glucan synthetase activity","type":"related"},{"name":"callose synthase activity","type":"exact"},{"name":"callose synthetase activity","type":"related"},{"name":"paramylon synthetase","type":"related"},{"name":"uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity","type":"related"}],"termid":"GO:0003843","terms_by_termid":{"GO:0003843":null,"GO:0140752":null}}


id: PBO:0089648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial DUF3818 and PXA domain conserved fungal protein","termid":"PBO:0089648"}


id: GO:0140828
data:
  {"annotated_genes":["SJAG_04698","SJAG_04028","SJAG_04616","SJAG_01541","SJAG_04096"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[78212,70012,90966],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015369"},{"annotations":[90967],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010486"},{"annotations":[79869],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015386"},{"annotations":[79868,77890],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015385"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(in) = solute(in) + Na+(out).","definition_xrefs":["GOC:pg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antiporter activity","termid":"GO:0015297"},{"relation_name":"is_a","term_name":"metal ion transmembrane transporter activity","termid":"GO:0046873"}],"gene_count":5,"genes_by_uniquename":{"SJAG_01541":null,"SJAG_04028":null,"SJAG_04096":null,"SJAG_04616":null,"SJAG_04698":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"metal cation:monoatomic cation antiporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"solute:metal cation antiporter activity","type":"broad"}],"termid":"GO:0140828","terms_by_termid":{"GO:0010486":null,"GO:0015369":null,"GO:0015385":null,"GO:0015386":null}}


id: PBO:0067954
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 256","termid":"PBO:0067954"}


id: GO:0034013
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O.","definition_xrefs":["RHEA:11316"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nitrogen-oxygen hydrolyase activity","termid":"GO:0141122"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"aliphatic aldoxime dehydratase activity","secondary_identifiers":["EC:4.8.1.2","MetaCyc:4.99.1.5-RXN"],"synonyms":[{"name":"aliphatic aldoxime hydro-lyase activity","type":"exact"}],"termid":"GO:0034013"}


id: PR:Q10061
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- lsh1 gene.","definition_xrefs":["UniProtKB:Q10061","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein 70 homolog lhs1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1F5.06","synonyms":[{"name":"Spom972h-lsh1","type":"exact"}],"termid":"PR:Q10061"}


id: PBO:0005630
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome component alpha 2, Pre8 (predicted)","termid":"PBO:0005630"}


id: PBO:0072363
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S26 pseudogene 49","termid":"PBO:0072363"}


id: PBO:0001576
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human Ini1","termid":"PBO:0001576"}


id: PBO:0005560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alcohol dehydrogenase Adh1","termid":"PBO:0005560"}


id: PBO:0056497
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methyl-CpG binding domain protein 3 like 2","termid":"PBO:0056497"}


id: PBO:0066961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 263","termid":"PBO:0066961"}


id: PR:O13782
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cpp1 gene.","definition_xrefs":["UniProtKB:O13782","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein farnesyltransferase subunit beta (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17G6.04c","synonyms":[{"name":"CAAX farnesyltransferase subunit beta (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"FTase-beta (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-cpp1","type":"exact"},{"name":"ras proteins prenyltransferase subunit beta (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O13782"}


id: PBO:0058684
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6812","termid":"PBO:0058684"}


id: GO:0010482
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.","definition_xrefs":["PMID:17450124"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell division","termid":"GO:0051302"},{"relation_name":"regulates","term_name":"epidermal cell division","termid":"GO:0010481"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of epidermal cell division","synonyms":[{"name":"regulation of hypodermal cell division","type":"related"}],"termid":"GO:0010482"}


id: PBO:0068313
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNF14 pseudogene 1","termid":"PBO:0068313"}


id: PATO:0001344
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A S. cerevisiae mating type cells that secrete a pheromone that stimulates a haploids.","definition_xrefs":["MGED:MGED"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Saccharomyces cerevisiae mating type","termid":"PATO:0001342"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha mating type (yeast)","synonyms":[{"name":"alpha","type":"broad"}],"termid":"PATO:0001344"}


id: PBO:0086053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function, secreted when constitutively expressed; SWAT-GFP fusion protein localizes to the endoplasmic reticulum (ER) and extracellular region, while mCherry fusion protein localizes to the ER and vacuole; mRNA identified as translated by ribosome profiling data; CSS2 is a non-essential gene","termid":"PBO:0086053"}


id: PBO:0034043
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-allelopath_of","termid":"PBO:0034043"}


id: MONDO:0020071
data:
  {"annotated_genes":["SJAG_02848","SJAG_02384","SJAG_01851","SJAG_04157","SJAG_01059","SJAG_02084","SJAG_02180","SJAG_01797"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86162],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014392"},{"annotations":[85029],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014593"},{"annotations":[85040,85039],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014598"},{"annotations":[85005,85003,85004],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014625"},{"annotations":[86925],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014933"}]},"cv_name":"mondo","definition":"An epilepsy syndrome that occurs between 28 days to one year of life.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epilepsy syndrome","termid":"MONDO:0015650"}],"gene_count":8,"genes_by_uniquename":{"SJAG_01059":null,"SJAG_01797":null,"SJAG_01851":null,"SJAG_02084":null,"SJAG_02180":null,"SJAG_02384":null,"SJAG_02848":null,"SJAG_04157":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"infantile epilepsy syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5681523","Orphanet:98258","GARD:19436","MEDGEN:1826124"],"synonyms":[{"name":"epilepsy syndrome of infancy","type":"exact"},{"name":"infantile epilepsy syndrome","type":"exact"},{"name":"infantile onset epilepsy syndrome","type":"exact"}],"termid":"MONDO:0020071","terms_by_termid":{"MONDO:0014392":null,"MONDO:0014593":null,"MONDO:0014598":null,"MONDO:0014625":null,"MONDO:0014933":null},"xrefs":{"Monarch":{"xref_id":"0020071"}}}


id: PBO:0029925
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_ionizing_radiation_during_vegetative_growth","termid":"PBO:0029925"}


id: GO:0019779
data:
  {"annotated_genes":["SJAG_00645"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73047],"is_not":false,"summary":null,"term":"GO:0019779"}]},"cv_name":"molecular_function","definition":"Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ubiquitin-like modifier activating enzyme activity","termid":"GO:0008641"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00645":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0140096","GO:0016874","GO:0003824"],"is_obsolete":false,"name":"Atg8 activating enzyme activity","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"APG7","type":"exact"},{"name":"APG8 activating enzyme activity","type":"related"}],"termid":"GO:0019779","terms_by_termid":{"GO:0019779":null}}


id: GO:0071011
data:
  {"annotated_genes":["SJAG_00147","SJAG_03469","SJAG_02469","SJAG_01819","SJAG_05208","SJAG_01308","SJAG_00313","SJAG_00504","SJAG_03430","SJAG_02304","SJAG_03460","SJAG_04529","SJAG_03410","SJAG_01870","SJAG_00322","SJAG_01301","SJAG_03245"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[70150,72507,73027,74860,75192,75423,75766,75831,76074,76493,76797,77226,78568,79151,80071,112625],"is_not":false,"summary":null,"term":"GO:0071011"},{"annotations":[105390],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071005"}]},"cv_name":"cellular_component","definition":"A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.","definition_xrefs":["PMID:19239890","PMID:18322460","GOC:ab","GOC:krc","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spliceosomal complex","termid":"GO:0005681"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00147":null,"SJAG_00313":null,"SJAG_00322":null,"SJAG_00504":null,"SJAG_01301":null,"SJAG_01308":null,"SJAG_01819":null,"SJAG_01870":null,"SJAG_02304":null,"SJAG_02469":null,"SJAG_03245":null,"SJAG_03410":null,"SJAG_03430":null,"SJAG_03460":null,"SJAG_03469":null,"SJAG_04529":null,"SJAG_05208":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005634","GO:0005575","GO:0032991"],"is_obsolete":false,"name":"precatalytic spliceosome","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"mammalian spliceosomal complex B","type":"narrow"},{"name":"mammalian spliceosomal complex B1","type":"narrow"},{"name":"yeast spliceosomal complex A2-1","type":"narrow"}],"termid":"GO:0071011","terms_by_termid":{"GO:0071005":null,"GO:0071011":null}}


id: SO:0001116
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A right handed helix is a region of peptide where the coiled conformation turns in a clockwise, right handed screw.","definition_xrefs":["EBIBS:GAR"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptide_helix","termid":"SO:0001114"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"right_handed_peptide_helix","secondary_identifiers":["BS:0000339"],"synonyms":[{"name":"helix","type":"related"},{"name":"right handed helix","type":"exact"}],"termid":"SO:0001116"}


id: PBO:0077167
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tousled like kinase 1","termid":"PBO:0077167"}


id: PBO:0040717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BAF chromatin remodeling complex subunit BCL7C","termid":"PBO:0040717"}


id: PBO:0089925
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aspartyl metalloaminopeptidase Ape4","termid":"PBO:0089925"}


id: GO:0006542
data:
  {"annotated_genes":["SJAG_00359"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71150],"is_not":false,"summary":null,"term":"GO:0006542"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glutamine metabolic process","termid":"GO:0006541"},{"relation_name":"is_a","term_name":"glutamine family amino acid biosynthetic process","termid":"GO:0009084"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00359":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006520"],"is_obsolete":false,"name":"glutamine biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:GLNSYN-PWY"],"synonyms":[{"name":"glutamine anabolism","type":"exact"},{"name":"glutamine biosynthesis","type":"exact"},{"name":"glutamine formation","type":"exact"},{"name":"glutamine synthesis","type":"exact"}],"termid":"GO:0006542","terms_by_termid":{"GO:0006542":null}}


id: GO:0102539
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.","definition_xrefs":["GOC:pz","PMID:10627048"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity","secondary_identifiers":["MetaCyc:RXN-14769"],"termid":"GO:0102539"}


id: PBO:0053833
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1098","termid":"PBO:0053833"}


id: MONDO:0044916
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rhabdoid tumor which arises in the soft tissues. It occurs in infants and children and may be associated with loss of chromosome 22. It is characterized by the presence of cells with a large eccentric nucleus, prominent nucleolus, and abundant cytoplasm.","definition_xrefs":["NCIT:C6586"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rhabdoid tumor","termid":"MONDO:0002728"},{"relation_name":"is_a","term_name":"childhood malignant neoplasm","termid":"MONDO:0006517"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"extrarenal rhabdoid tumor","secondary_identifiers":["SCTID:404089007","MEDGEN:224918","UMLS:C1304517"],"synonyms":[{"name":"extrarenal rhabdoid tumor","type":"exact"},{"name":"malignant extrarenal rhabdoid neoplasm","type":"exact"},{"name":"rhabdoid tumor of soft tissue","type":"exact"},{"name":"rhabdoid tumour of soft tissue","type":"exact"}],"termid":"MONDO:0044916","xrefs":{"Monarch":{"xref_id":"0044916"}}}


id: GO:0005925
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).","definition_xrefs":["PMID:23033047","PMID:28796323","PMID:8314002","PMID:16805308","PMID:12191915","GOC:aruk","ISBN:0124325653","PMID:10419689","PMID:1643657","PMID:26923917","GOC:bc","PMID:15246682","PMID:19197329","ISBN:0815316208"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-substrate junction","termid":"GO:0030055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"focal adhesion","secondary_identifiers":["GO:0005926","GO:0008357","Wikipedia:Focal_adhesion"],"synonyms":[{"name":"HAJ","type":"exact"},{"name":"adhesion plaque","type":"related"},{"name":"connecting hemi-adherens junction","type":"exact"},{"name":"focal contact","type":"exact"},{"name":"hemi-adherens junction","type":"exact"}],"termid":"GO:0005925"}


id: MONDO:0019449
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Lissencephaly type 3-familial fetal akinesia sequence syndrome is characterized by the association of microencephaly, agenesis of the corpus callosum, brainstem hypoplasia, cystic cerebellum and fetal akinesia sequence. Less than 10 cases have been described so far. The syndrome is transmitted as an autosomal recessive trait and may be an allelic variant of Neu-Laxova syndrome and lissencephaly type III with metacarpal bone dysplasia.","definition_xrefs":["Orphanet:86821"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lissencephaly type 3","termid":"MONDO:0015148"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"lissencephaly type 3-familial fetal akinesia sequence syndrome","secondary_identifiers":["GARD:19067","MEDGEN:930924","SCTID:718719001","UMLS:C4305255"],"termid":"MONDO:0019449","xrefs":{"Monarch":{"xref_id":"0019449"}}}


id: GO:0035881
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.","definition_xrefs":["GOC:bf","CL:0000561"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system neuron differentiation","termid":"GO:0021953"},{"relation_name":"part_of","term_name":"neural retina development","termid":"GO:0003407"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"amacrine cell differentiation","synonyms":[{"name":"amacrine neuron differentiation","type":"exact"}],"termid":"GO:0035881"}


id: RO:0002353
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"inverse of has output","direct_ancestors":[{"relation_name":"is_a","term_name":"participates_in","termid":"RO:0000056"},{"relation_name":"is_a","term_name":"functionally_related_to","termid":"RO:0002328"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"output_of","termid":"RO:0002353"}


id: MONDO:0003687
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm involving the endocardium.","direct_ancestors":[{"relation_name":"is_a","term_name":"heart cancer","termid":"MONDO:0001340"},{"relation_name":"is_a","term_name":"neoplasm of endocardium","termid":"MONDO:0021378"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005267"],"is_obsolete":false,"name":"endocardium cancer","secondary_identifiers":["SCTID:363436001","UMLS:C0346612","NCIT:C4570","DOID:5877","MEDGEN:91107"],"synonyms":[{"name":"cancer of endocardium","type":"exact"},{"name":"endocardium cancer","type":"exact"},{"name":"malignant endocardial neoplasm","type":"exact"},{"name":"malignant endocardial tumor","type":"exact"},{"name":"malignant endocardial tumour","type":"exact"},{"name":"malignant endocardium neoplasm","type":"exact"},{"name":"malignant neoplasm of endocardium","type":"exact"},{"name":"malignant neoplasm of the endocardium","type":"exact"},{"name":"malignant tumor of endocardium","type":"exact"},{"name":"malignant tumor of the endocardium","type":"exact"},{"name":"malignant tumour of endocardium","type":"exact"},{"name":"malignant tumour of the endocardium","type":"exact"}],"termid":"MONDO:0003687","xrefs":{"Monarch":{"xref_id":"0003687"}}}


id: GO:0006063
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid metabolic process","termid":"GO:0032787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"uronic acid metabolic process","synonyms":[{"name":"uronic acid metabolism","type":"exact"}],"termid":"GO:0006063"}


id: GO:1902596
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding.","definition_xrefs":["GOC:TermGenie","GO_REF:0000059","PMID:11850415"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of DNA binding","termid":"GO:0043392"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of DNA replication origin binding","synonyms":[{"name":"down regulation of ARS binding","type":"narrow"},{"name":"down regulation of DNA replication origin binding","type":"exact"},{"name":"down-regulation of ARS binding","type":"narrow"},{"name":"down-regulation of DNA replication origin binding","type":"exact"},{"name":"downregulation of ARS binding","type":"narrow"},{"name":"downregulation of DNA replication origin binding","type":"exact"},{"name":"inhibition of ARS binding","type":"narrow"},{"name":"inhibition of DNA replication origin binding","type":"narrow"},{"name":"negative regulation of ARS binding","type":"narrow"}],"termid":"GO:1902596"}


id: MOD:00700
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively results from forming an adduct with a compound containing a tetrapyrrole group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by chemical process","termid":"MOD:01156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetrapyrrole modified residue","synonyms":[{"name":"TetrapyrRes","type":"exact"}],"termid":"MOD:00700"}


id: PBO:0061704
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NUS1 pseudogene 4","termid":"PBO:0061704"}


id: GO:0060236
data:
  {"annotated_genes":["SJAG_02332","SJAG_00244","SJAG_00514","SJAG_04464"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89633],"is_not":false,"summary":null,"term":"GO:0060236"},{"annotations":[111184],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110161"},{"annotations":[71185],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901673"},{"annotations":[114793],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110162"}]},"cv_name":"biological_process","definition":"Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.","definition_xrefs":["GOC:dph","GOC:ascb_2009","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of spindle organization","termid":"GO:0090224"},{"relation_name":"regulates","term_name":"mitotic spindle organization","termid":"GO:0007052"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00244":null,"SJAG_00514":null,"SJAG_02332":null,"SJAG_04464":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0000226"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0000226","GO:0008150","GO:0007010","GO:0007049"],"is_obsolete":false,"name":"regulation of mitotic spindle organization","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-380320"],"synonyms":[{"name":"regulation of mitotic spindle organisation","type":"exact"},{"name":"regulation of mitotic spindle organization and biogenesis","type":"related"}],"termid":"GO:0060236","terms_by_termid":{"GO:0060236":null,"GO:0110161":null,"GO:0110162":null,"GO:1901673":null}}


id: PBO:0083071
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dihydroxyacetone kinase; required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation","termid":"PBO:0083071"}


id: PBO:0082441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"B-type cyclin involved in cell cycle progression; also involved in response to DNA damage; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB2 has a paralog, CLB1, that arose from the whole genome duplication","termid":"PBO:0082441"}


id: PBO:0086253
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that plays a role in modification of tRNA wobble nucleosides; protein plays role in tRNA wobble nucleoside modification with Elongator complex; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p","termid":"PBO:0086253"}


id: PBO:0068841
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 79, pseudogene","termid":"PBO:0068841"}


id: PBO:0047837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"forkhead box R2","termid":"PBO:0047837"}


id: PBO:0043111
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CHUK divergent transcript","termid":"PBO:0043111"}


id: MONDO:0021202
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A otitis media (disease) with a basis in a pathological type I hypersensitivity reaction.","definition_xrefs":["MONDO:patterns/allergic_form_of_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"allergic disease","termid":"MONDO:0005271"},{"relation_name":"is_a","term_name":"otitis media","termid":"MONDO:0005441"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"allergic otitis media","secondary_identifiers":["MEDGEN:543352","SCTID:26169004","UMLS:C0271447"],"synonyms":[{"name":"allergic form of otitis media (disease)","type":"exact"},{"name":"allergic otitis media (disease)","type":"exact"}],"termid":"MONDO:0021202","xrefs":{"Monarch":{"xref_id":"0021202"}}}


id: GO:0102756
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon dioxide + coenzyme A + a very-long-chain oxoacyl-CoA.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete very-long-chain 3-ketoacyl-CoA synthase activity (obsolete GO:0102756)","termid":"GO:0102756"}


id: MONDO:0019861
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Thyroid hypoplasia is a form of thyroid dysgenesis characterized by incomplete development of the thyroid gland that results in primary congenital hypothyroidism, a permanent thyroid deficiency that is present from birth.","definition_xrefs":["Orphanet:95720"],"direct_ancestors":[{"relation_name":"is_a","term_name":"generalized resistance to thyroid hormone","termid":"MONDO:0009043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"thyroid hypoplasia","secondary_identifiers":["icd11.foundation:936952450","MedDRA:10065938","UMLS:C0151516","MEDGEN:57720","GARD:8426"],"termid":"MONDO:0019861","xrefs":{"Monarch":{"xref_id":"0019861"}}}


id: PBO:0089997
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thioredoxin-related chaperone Pmp20","termid":"PBO:0089997"}


id: PBO:0081809
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 736 pseudogene 2, Y-linked","termid":"PBO:0081809"}


id: PBO:0051884
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ITCH antisense RNA 1","termid":"PBO:0051884"}


id: PBO:0085709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in sphingolipid biosynthesis; type II membrane protein; SKN1 has a paralog, KRE6, that arose from the whole genome duplication","termid":"PBO:0085709"}


id: PBO:0072054
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S10 pseudogene 24","termid":"PBO:0072054"}


id: GO:0043518
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of DNA damage response, signal transduction by p53 class mediator","termid":"GO:0043516"},{"relation_name":"is_a","term_name":"negative regulation of signal transduction by p53 class mediator","termid":"GO:1901797"},{"relation_name":"negatively_regulates","term_name":"DNA damage response, signal transduction by p53 class mediator","termid":"GO:0030330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of DNA damage response, signal transduction by p53 class mediator","synonyms":[{"name":"down regulation of DNA damage response, signal transduction by p53 class mediator","type":"exact"},{"name":"down-regulation of DNA damage response, signal transduction by p53 class mediator","type":"exact"},{"name":"downregulation of DNA damage response, signal transduction by p53 class mediator","type":"exact"},{"name":"inhibition of DNA damage response, signal transduction by p53 class mediator","type":"narrow"},{"name":"negative regulation of p53 induced by DNA damage response","type":"exact"}],"termid":"GO:0043518"}


id: GO:1902640
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of propan-2-ol.","definition_xrefs":["GOC:TermGenie","GOC:mengo_curators","PMID:16346237","GO_REF:0000068"],"direct_ancestors":[{"relation_name":"is_a","term_name":"propan-2-ol metabolic process","termid":"GO:1902639"},{"relation_name":"is_a","term_name":"secondary alcohol biosynthetic process","termid":"GO:1902653"},{"relation_name":"is_a","term_name":"fatty alcohol biosynthetic process","termid":"GO:1903175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"propan-2-ol biosynthetic process","synonyms":[{"name":"Isopropanol biosynthetic process","type":"exact"},{"name":"Isopropyl alcohol biosynthetic process","type":"exact"},{"name":"propan-2-ol anabolism","type":"exact"},{"name":"propan-2-ol biosynthesis","type":"exact"},{"name":"propan-2-ol formation","type":"exact"},{"name":"propan-2-ol synthesis","type":"exact"}],"termid":"GO:1902640"}


id: MONDO:0014973
data:
  {"annotated_genes":["SJAG_01875","SJAG_02679"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86757,86758],"is_not":false,"summary":null,"term":"MONDO:0014973"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01875":null,"SJAG_02679":null},"genotype_count":0,"is_obsolete":false,"name":"sudden cardiac failure, infantile","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4310664","OMIM:617222","MEDGEN:934631"],"synonyms":[{"name":"PPA2 deficiency","type":"broad"},{"name":"PPA2-associated sudden cardiac death","type":"exact"},{"name":"SCFI","type":"exact"},{"name":"infantile sudden cardiac failure","type":"exact"},{"name":"sudden Cardiac failure, infantile","type":"exact"},{"name":"sudden cardiac failure, infantile; SCFI","type":"exact"}],"termid":"MONDO:0014973","terms_by_termid":{"MONDO:0014973":null},"xrefs":{"Monarch":{"xref_id":"0014973"}}}


id: MONDO:0019034
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Accessory pancreas is an asymptomatic embryopathy characterized by the presence of pancreatic tissue in other sites of the body such as the splenic pedicle, gonadic pedicles, intestinal mesentery, duodenum wall, upper jejunum, or, more rarely, the gastric wall, ileum, gallbladder or spleen.","definition_xrefs":["Orphanet:674"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreas disorder","termid":"MONDO:0002356"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"accessory pancreas","secondary_identifiers":["icd11.foundation:240534435","MEDGEN:82737","MESH:C536003","SCTID:79037006","UMLS:C0266268","GARD:454"],"synonyms":[{"name":"pancreas accessorium","type":"related"}],"termid":"MONDO:0019034","xrefs":{"Monarch":{"xref_id":"0019034"}}}


id: GO:0032701
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.","definition_xrefs":["GOC:mah","PMID:23710316"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cytokine production","termid":"GO:0001818"},{"relation_name":"is_a","term_name":"regulation of interleukin-18 production","termid":"GO:0032661"},{"relation_name":"negatively_regulates","term_name":"interleukin-18 production","termid":"GO:0032621"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of interleukin-18 production","secondary_identifiers":["GO:0045382","GO:0150121"],"synonyms":[{"name":"down regulation of interleukin-18 production","type":"exact"},{"name":"down-regulation of interleukin-18 production","type":"exact"},{"name":"downregulation of interleukin-18 production","type":"exact"},{"name":"inhibition of interleukin-18 production","type":"narrow"},{"name":"negative regulation of IL-18 production","type":"exact"},{"name":"negative regulation of interleukin-18 biosynthetic process","type":"narrow"},{"name":"negative regulation of interleukin-18 secretion","type":"narrow"}],"termid":"GO:0032701"}


id: PBO:0065963
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAD51 recombinase","termid":"PBO:0065963"}


id: MONDO:0000138
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Pyle disease","termid":"MONDO:0009943"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"metaphyseal chondrodysplasia","secondary_identifiers":["MEDGEN:120528","HP:0005871","UMLS:C0265290","SCTID:28681006"],"synonyms":[{"name":"metaphyseal chondrodysplasia","type":"exact"},{"name":"metaphyseal chondrodysplasia (disease)","type":"exact"}],"termid":"MONDO:0000138","xrefs":{"Monarch":{"xref_id":"0000138"}}}


id: GO:0140571
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.","definition_xrefs":["PMID:16911521","PMID:24449903","RHEA:30403"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreduction-driven active transmembrane transporter activity","termid":"GO:0015453"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on metal ions","termid":"GO:0016722"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0005215","GO:0003824","GO:0022857","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"transmembrane ascorbate ferrireductase activity","secondary_identifiers":["EC:7.2.1.3","MetaCyc:RXN-15598"],"synonyms":[{"name":"L-ascorbate-cytochrome-b5 reductase activity","type":"exact"},{"name":"L-ascorbate:ferricytochrome-b5 oxidoreductase activity","type":"exact"},{"name":"ascorbate-cytochrome b5 reductase activity","type":"exact"}],"termid":"GO:0140571"}


id: MONDO:0012585
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any coronary artery disease in which the cause of the disease is a mutation in the CD36 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coronary heart disease, susceptibility to, 7","secondary_identifiers":["OMIM:610938","UMLS:C1970441","MEDGEN:370260"],"synonyms":[{"name":"CD36 coronary artery disease","type":"exact"},{"name":"CHDS7","type":"related"},{"name":"coronary artery disease caused by mutation in CD36","type":"exact"},{"name":"coronary heart disease, susceptibility to, 7","type":"exact"},{"name":"coronary heart disease, susceptibility to, type 7","type":"exact"},{"name":"susceptibility to coronary heart disease 7","type":"related"}],"termid":"MONDO:0012585","xrefs":{"Monarch":{"xref_id":"0012585"}}}


id: GO:0036341
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle.","definition_xrefs":["GOC:bf","GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chitin-based cuticle sclerotization","termid":"GO:0007593"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chitin-based cuticle sclerotization by protein cross-linking","synonyms":[{"name":"chitin-based cuticle sclerotization by protein cross-linking and cuticle tanning","type":"narrow"}],"termid":"GO:0036341"}


id: PBO:0051494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin superfamily member 11","termid":"PBO:0051494"}


id: PR:P31406
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A V-type proton ATPase catalytic subunit A that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR15184:SF7","PRO:DNx","OMA:SCHPO00670"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-type proton ATPase catalytic subunit A (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC343.05","secondary_identifiers":["UniProtKB:P31406"],"synonyms":[{"name":"Spom972h-ATP6V1A","type":"exact"},{"name":"V-ATPase 67 kDa subunit (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"V-ATPase subunit A (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"vacuolar proton pump subunit alpha (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P31406"}


id: GO:0070241
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.","definition_xrefs":["GOC:add","ISBN:0781765196","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of immune system process","termid":"GO:0002684"},{"relation_name":"is_a","term_name":"positive regulation of T cell apoptotic process","termid":"GO:0070234"},{"relation_name":"is_a","term_name":"regulation of activated T cell autonomous cell death","termid":"GO:0070239"},{"relation_name":"positively_regulates","term_name":"activated T cell autonomous cell death","termid":"GO:0070238"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of activated T cell autonomous cell death","synonyms":[{"name":"activation of activated T cell autonomous cell death","type":"narrow"},{"name":"positive regulation of ACAD","type":"broad"},{"name":"positive regulation of activated T cell apoptosis","type":"broad"},{"name":"positive regulation of activated T lymphocyte autonomous cell death","type":"exact"},{"name":"positive regulation of activated T-cell autonomous cell death","type":"exact"},{"name":"positive regulation of activated T-lymphocyte autonomous cell death","type":"exact"},{"name":"positive regulation of activated cell autonomous cell death","type":"broad"},{"name":"stimulation of activated T cell autonomous cell death","type":"narrow"},{"name":"up regulation of activated T cell autonomous cell death","type":"exact"},{"name":"up-regulation of activated T cell autonomous cell death","type":"exact"},{"name":"upregulation of activated T cell autonomous cell death","type":"exact"}],"termid":"GO:0070241"}


id: GO:0039647
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation.","definition_xrefs":["UniProtKB-KW:KW-1101"],"gene_count":0,"genotype_count":0,"name":"obsolete suppression by virus of host poly(A)-binding protein activity (obsolete GO:0039647)","synonyms":[{"name":"inhibition of host poly(A)-binding protein by virus","type":"exact"},{"name":"suppression by virus of host PABP activity","type":"exact"}],"termid":"GO:0039647"}


id: PR:Q9Y818
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A ubiquitin-conjugating enzyme E2 G1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03741","PANTHER:PTHR24067:SF36","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-conjugating enzyme E2 15 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1105.09","secondary_identifiers":["UniProtKB:Q9Y818"],"synonyms":[{"name":"E2 ubiquitin-conjugating enzyme 15 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-UBE2G1","type":"exact"},{"name":"ubiquitin carrier protein 15 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin-protein ligase 15 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9Y818"}


id: PBO:0030034
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_leptomycin_B_binding","termid":"PBO:0030034"}


id: FYPO:0002911
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which a spore germinates to produce an elongated germ tube that has a larger diameter and volume than normal, and does not go on to form a viable dividing cell.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable swollen elongated vegetative cell","termid":"FYPO:0002251"},{"relation_name":"is_a","term_name":"inviable after spore germination, without cell division, with elongated germ tube","termid":"FYPO:0002379"},{"relation_name":"is_a","term_name":"inviable swollen vegetative cell with abnormal cell shape","termid":"FYPO:0002415"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000004"}],"interesting_parent_ids":["FYPO:0000005","FYPO:0000004","FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"inviable after spore germination, without cell division, with swollen elongated germ tube","synonyms":[{"name":"inviable after spore germination with elongated swollen germ tube","type":"exact"},{"name":"inviable after spore germination, without cell division, swollen elongated cell","type":"related"},{"name":"inviable following spore germination with swollen elongated germ tube","type":"exact"},{"name":"inviable germinated spore with swollen elongated germ tube","type":"exact"},{"name":"lethal after spore germination, without cell division, with swollen elongated germ tube","type":"exact"}],"termid":"FYPO:0002911"}


id: PBO:0018124
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab GTPase binding involved in ER to Golgi vesicle transport Yip3 (predicted)","termid":"PBO:0018124"}


id: MONDO:0007576
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm involving the esophagus.","definition_xrefs":["NCIT:C7478"],"direct_ancestors":[{"relation_name":"is_a","term_name":"digestive system cancer","termid":"MONDO:0002516"},{"relation_name":"is_a","term_name":"thoracic cancer","termid":"MONDO:0003274"},{"relation_name":"is_a","term_name":"neoplasm of esophagus","termid":"MONDO:0021355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"esophageal cancer","secondary_identifiers":["ICD9:150.4","MEDGEN:107792","OMIM:133239","ICD9:150.3","SCTID:363402007","DOID:5041","SCTID:187724003","ICD9:150.2","NCIT:C4764","UMLS:C0546837","ICD9:150.5","ICD9:150.8","ICD9:150.9"],"synonyms":[{"name":"Aerodigestive tract cancer, susceptibility to","type":"related"},{"name":"Ca lower third esophagus","type":"narrow"},{"name":"Ca lower third oesophagus","type":"narrow"},{"name":"Ca middle third esophagus","type":"narrow"},{"name":"Ca middle third oesophagus","type":"narrow"},{"name":"Escc, susceptibility to","type":"related"},{"name":"cancer of esophagus","type":"exact"},{"name":"cancer of oesophagus","type":"exact"},{"name":"esophageal cancer","type":"exact"},{"name":"esophageal cancer, somatic","type":"exact"},{"name":"esophageal carcinoma, somatic","type":"exact"},{"name":"esophageal squamous cell carcinoma, somatic","type":"exact"},{"name":"esophageal squamous cell carcinoma, susceptibility to","type":"related"},{"name":"esophagus cancer","type":"exact"},{"name":"gastric cardia adenocarcinoma, susceptibility to","type":"related"},{"name":"malignant esophageal neoplasm","type":"exact"},{"name":"malignant esophageal tumor","type":"exact"},{"name":"malignant esophageal tumour","type":"exact"},{"name":"malignant esophagus neoplasm","type":"exact"},{"name":"malignant esophagus tumor","type":"exact"},{"name":"malignant neoplasm of distal third of esophagus","type":"narrow"},{"name":"malignant neoplasm of distal third of oesophagus","type":"narrow"},{"name":"malignant neoplasm of esophagus","type":"exact"},{"name":"malignant neoplasm of lower third of esophagus","type":"narrow"},{"name":"malignant neoplasm of lower third of oesophagus","type":"narrow"},{"name":"malignant neoplasm of middle third of esophagus","type":"narrow"},{"name":"malignant neoplasm of middle third of oesophagus","type":"narrow"},{"name":"malignant neoplasm of oesophagus","type":"exact"},{"name":"malignant neoplasm of proximal third of esophagus","type":"narrow"},{"name":"malignant neoplasm of proximal third of oesophagus","type":"narrow"},{"name":"malignant neoplasm of the esophagus","type":"exact"},{"name":"malignant neoplasm of the oesophagus","type":"exact"},{"name":"malignant neoplasm of upper third esophagus","type":"narrow"},{"name":"malignant neoplasm of upper third oesophagus","type":"narrow"},{"name":"malignant oesophagus neoplasm","type":"exact"},{"name":"malignant oesophagus tumour","type":"exact"},{"name":"malignant tumor of abdominal esophagus","type":"narrow"},{"name":"malignant tumor of distal third of esophagus","type":"narrow"},{"name":"malignant tumor of esophagus","type":"exact"},{"name":"malignant tumor of proximal third of esophagus","type":"narrow"},{"name":"malignant tumor of the esophagus","type":"exact"},{"name":"malignant tumor of the middle third of the esophagus","type":"narrow"},{"name":"malignant tumour of abdominal oesophagus","type":"narrow"},{"name":"malignant tumour of distal third of oesophagus","type":"narrow"},{"name":"malignant tumour of oesophagus","type":"exact"},{"name":"malignant tumour of proximal third of oesophagus","type":"narrow"},{"name":"malignant tumour of the middle third of the oesophagus","type":"narrow"},{"name":"malignant tumour of the oesophagus","type":"exact"},{"name":"oesophagus cancer","type":"exact"}],"termid":"MONDO:0007576","xrefs":{"Monarch":{"xref_id":"0007576"}}}


id: BFO:0000055
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"realizes","termid":"BFO:0000055"}


id: PBO:0004709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin-like protein Tea2","termid":"PBO:0004709"}


id: GO:0045159
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.","definition_xrefs":["PMID:27697842","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myosin binding","termid":"GO:0017022"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0008092"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0008092","GO:0005515"],"is_obsolete":false,"name":"myosin II binding","termid":"GO:0045159"}


id: PBO:0028417
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_meiosis_I","termid":"PBO:0028417"}


id: MONDO:0017138
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Opitz G/BBB syndrome (OS) is a multiple congenital anomalies disorder characterized by malformations of the midline including hypertelorism, laryngo-tracheo-esophalgeal defects and hypospadias. There are two clinically indistinguishable genetic subtypes of Opitz G/BBB: X-linked Opitz G/BBB syndrome (XLOS), and autosomal dominant Opitz G/BBB syndrome (ADOS).","definition_xrefs":["Orphanet:2745"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"telecanthus","termid":"MONDO:0008537"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"Opitz G/BBB syndrome","secondary_identifiers":["DOID:0080697","NCIT:C125487","GARD:193","OMIMPS:300000","DOID:0050780","ICD9:758.89","SCTID:81771002"],"synonyms":[{"name":"BBB syndrome","type":"related"},{"name":"G syndrome","type":"related"},{"name":"GBBB syndrome","type":"related"},{"name":"Opitz BBBG syndrome","type":"related"},{"name":"Opitz G syndrome","type":"exact"},{"name":"Opitz G/BBB syndrome","type":"exact"},{"name":"Opitz GBBB syndrome","type":"exact"},{"name":"Opitz syndrome","type":"exact"},{"name":"Opitz-Frias syndrome","type":"exact"},{"name":"Opitz-G syndrome, type 2","type":"related"},{"name":"Opitz-GBBB syndrome","type":"exact"},{"name":"hypertelorism hypospadias syndrome","type":"related"},{"name":"hypertelorism with esophageal abnormality and hypospadias","type":"related"},{"name":"hypertelorism-oesophageal abnormality-hypospadias syndrome","type":"exact"},{"name":"hypospadias-dysphagia syndrome","type":"exact"},{"name":"hypospadias-dysphagia, syndrome","type":"related"},{"name":"hypospadias-hypertelorism syndrome","type":"exact"},{"name":"telecanthus with associated abnormalities","type":"related"}],"termid":"MONDO:0017138","xrefs":{"Monarch":{"xref_id":"0017138"}}}


id: PBO:0109090
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sperm microtubule inner protein 4","termid":"PBO:0109090"}


id: FYPO:0000362
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the peroxisome is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal subcellular component during vegetative growth","termid":"FYPO:0001322"},{"relation_name":"output_of","term_name":"abnormal peroxisome organization","termid":"FYPO:0000811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abnormal peroxisomal morphology","synonyms":[{"name":"abnormal peroxisomal morphology during mitotic cell cycle","type":"related"},{"name":"abnormal peroxisomal morphology during vegetative growth","type":"exact"},{"name":"peroxisomal morphology: abnormal","type":"related"}],"termid":"FYPO:0000362"}


id: GO:0070554
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).","definition_xrefs":["PMID:8824312"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SNARE complex","termid":"GO:0031201"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005737"],"is_obsolete":false,"name":"synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex","synonyms":[{"name":"SNARE complex (Stx3, Snap25, Vamp2, Cplx1)","type":"narrow"},{"name":"Stx3-Snap25-Vamp2-Cplx1 complex","type":"narrow"}],"termid":"GO:0070554"}


id: PBO:0034262
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-ribosomal_translation_of","termid":"PBO:0034262"}


id: FYPO:0001440
data:
  {"alleles_by_uniquename":{"SJAG_03250:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03250","name":"sst4delta","uniquename":"SJAG_03250:allele-1"},"SJAG_04349:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04349","name":"vps28delta","uniquename":"SJAG_04349:allele-1"},"SJAG_04912:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04912","name":"vps25delta","uniquename":"SJAG_04912:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[118971,118972,118973],"is_not":false,"summary":null,"term":"FYPO:0001440"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization","termid":"FYPO:0001370"}],"gene_count":3,"genes_by_uniquename":{"SJAG_03250":null,"SJAG_04349":null,"SJAG_04912":null},"genotype_count":3,"genotypes_by_uniquename":{"sst4delta":{"display_name":"sst4delta","display_uniquename":"sst4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03250:allele-1","expression":"Null"}]}]},"vps25delta":{"display_name":"vps25delta","display_uniquename":"vps25delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04912:allele-1","expression":"Null"}]}]},"vps28delta":{"display_name":"vps28delta","display_uniquename":"vps28delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04349:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abnormal protein complex localization","references_by_uniquename":{"PMID:32109380":null},"single_locus_annotated_genes":["SJAG_04349","SJAG_03250","SJAG_04912"],"single_locus_genotype_uniquenames":["vps28delta","sst4delta","vps25delta"],"synonyms":[{"name":"abnormal cellular protein complex localization","type":"exact"},{"name":"abnormal protein complex localisation","type":"exact"},{"name":"abnormal protein complex localization during mitotic cell cycle","type":"related"},{"name":"abnormal protein complex localization during vegetative growth","type":"exact"}],"termid":"FYPO:0001440","terms_by_termid":{"FYPO:0001440":null,"FYPO_EXT:0000001":null,"GO:0000815":null}}


id: FYPO:0000152
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A stress response phenotype in which the response to nitrogen starvation is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular response to starvation","termid":"FYPO:0000713"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000298","FYPO:0005447"],"is_obsolete":false,"name":"abnormal cellular response to nitrogen starvation","synonyms":[{"name":"abnormal cellular response to nitrogen depletion","type":"exact"},{"name":"abnormal cellular response to nitrogen deprivation","type":"exact"}],"termid":"FYPO:0000152"}


id: PBO:0077970
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ala (anticodon AGC) 22-1","termid":"PBO:0077970"}


id: PBO:0063587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxisomal biogenesis factor 2","termid":"PBO:0063587"}


id: PBO:0052707
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 17 pseudogene 8","termid":"PBO:0052707"}


id: GO:0035706
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a T-helper 1 cell in response to an external stimulus.","definition_xrefs":["CL:0000545","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"T cell chemotaxis","termid":"GO:0010818"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"T-helper 1 cell chemotaxis","synonyms":[{"name":"Th1 cell chemotaxis","type":"exact"}],"termid":"GO:0035706"}


id: MONDO:0008484
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Stapes ankylosis with broad thumbs and toes is a very rare genetic bone disorder characterized by ankylosis of stapes, broad thumbs and halluces, conductive hearing loss and hyperopia.","definition_xrefs":["Orphanet:140917"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NOG-related symphalangism spectrum disorder","termid":"MONDO:0100521"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"stapes ankylosis with broad thumbs and toes","secondary_identifiers":["icd11.foundation:387089262","UMLS:C1866656","GARD:12631","OMIM:184460","MEDGEN:357104","SCTID:719305006"],"synonyms":[{"name":"Teunissen-Cremers syndrome","type":"exact"},{"name":"ankylosis of stapes, hyperopia, Broad thumbs, Broad first toes, and syndactyly","type":"related"},{"name":"stapes ankylosis syndrome without symphalangism","type":"related"},{"name":"stapes ankylosis with BROAD thumb and toes","type":"related"}],"termid":"MONDO:0008484","xrefs":{"Monarch":{"xref_id":"0008484"}}}


id: SO:0001876
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A partial DNA sequence assembly of a chromosome or full genome, which contains gaps that are filled with N's.","definition_xrefs":["GMOD:ea"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sequence_assembly","termid":"SO:0000353"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial_genomic_sequence_assembly","synonyms":[{"name":"partial genomic sequence assembly","type":"exact"},{"name":"pseudomolecule","type":"broad"},{"name":"sequence assembly with N-gaps","type":"exact"}],"termid":"SO:0001876"}


id: GO:0047886
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP+ = 2-trans,6-trans-farnesal + H+ + NADPH.","definition_xrefs":["EC:1.1.1.216","RHEA:14697"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"farnesol dehydrogenase activity","secondary_identifiers":["MetaCyc:FARNESOL-DEHYDROGENASE-RXN","KEGG_REACTION:R03264"],"synonyms":[{"name":"2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity","type":"related"},{"name":"NADP-farnesol dehydrogenase activity","type":"related"},{"name":"farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity","type":"related"}],"termid":"GO:0047886"}


id: GO:0007147
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell cycle process in which the second meiotic division occurs in the female germline.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiosis II","termid":"GO:0007135"},{"relation_name":"is_a","term_name":"female meiotic nuclear division","termid":"GO:0007143"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140013"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0140013","GO:0007049","GO:0008150"],"is_obsolete":false,"name":"female meiosis II","synonyms":[{"name":"female meiosis II nuclear division","type":"exact"}],"termid":"GO:0007147"}


id: MONDO:0013791
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary thrombophilia due to congenital protein S deficiency","termid":"MONDO:0019144"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"thrombophilia due to protein S deficiency, autosomal recessive","secondary_identifiers":["MEDGEN:482722","GARD:18569","OMIM:614514","UMLS:C3281092"],"synonyms":[{"name":"THPH6","type":"related"},{"name":"thrombophilia 5 due to protein S deficiency, autosomal recessive","type":"exact"},{"name":"thrombophilia due to PROTEIN S deficiency, autosomal recessive","type":"related"},{"name":"thrombophilia due to protein S deficiency, autosomal recessive","type":"exact"}],"termid":"MONDO:0013791","xrefs":{"Monarch":{"xref_id":"0013791"}}}


id: PBO:0005813
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pombe CAspase 1","termid":"PBO:0005813"}


id: GO:0006081
data:
  {"annotated_genes":["SJAG_00281","SJAG_00501","SJAG_00070","SJAG_02106","SJAG_02988","SJAG_04192","SJAG_03174","SJAG_00252","SJAG_01543","SJAG_00691","SJAG_05256","SJAG_00283","SJAG_01881","SJAG_00707","SJAG_04263","SJAG_02960","SJAG_01432","SJAG_01596","SJAG_04674","SJAG_04404","SJAG_03934","SJAG_01457","SJAG_01383","SJAG_04726"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92584],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036001"},{"annotations":[95291,77924],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046294"},{"annotations":[71783],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046166"},{"annotations":[71416,72980],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903189"},{"annotations":[104850,100785],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009436"},{"annotations":[72518,60860,74247,102546],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019243"},{"annotations":[60859,59076,104810],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061727"},{"annotations":[72891,108183,73569,104110,74286],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009052"},{"annotations":[77931,74983],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009443"},{"annotations":[114133],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042821"},{"annotations":[64007,75295],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042823"},{"annotations":[111573],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010144"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic process","termid":"GO:0008152"}],"gene_count":24,"genes_by_uniquename":{"SJAG_00070":null,"SJAG_00252":null,"SJAG_00281":null,"SJAG_00283":null,"SJAG_00501":null,"SJAG_00691":null,"SJAG_00707":null,"SJAG_01383":null,"SJAG_01432":null,"SJAG_01457":null,"SJAG_01543":null,"SJAG_01596":null,"SJAG_01881":null,"SJAG_02106":null,"SJAG_02960":null,"SJAG_02988":null,"SJAG_03174":null,"SJAG_03934":null,"SJAG_04192":null,"SJAG_04263":null,"SJAG_04404":null,"SJAG_04674":null,"SJAG_04726":null,"SJAG_05256":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"aldehyde metabolic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"aldehyde metabolism","type":"exact"},{"name":"alkanal metabolic process","type":"exact"},{"name":"alkanal metabolism","type":"exact"}],"termid":"GO:0006081","terms_by_termid":{"GO:0009052":null,"GO:0009436":null,"GO:0009443":null,"GO:0010144":null,"GO:0019243":null,"GO:0036001":null,"GO:0042821":null,"GO:0042823":null,"GO:0046166":null,"GO:0046294":null,"GO:0061727":null,"GO:1903189":null}}


id: PBO:0044208
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cathepsin L pseudogene 8","termid":"PBO:0044208"}


id: GO:0070742
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.","definition_xrefs":["GOC:BHF","GOC:mah","Pfam:PF00096"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein domain specific binding","termid":"GO:0019904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"C2H2 zinc finger domain binding","termid":"GO:0070742"}


id: GO:0016918
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinoid binding","termid":"GO:0005501"},{"relation_name":"is_a","term_name":"vitamin binding","termid":"GO:0019842"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0008289"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0008289","GO:0005488"],"is_obsolete":false,"name":"retinal binding","synonyms":[{"name":"UV-sensitive opsin","type":"related"},{"name":"blue-sensitive opsin","type":"related"},{"name":"green-sensitive opsin","type":"related"},{"name":"long-wave-sensitive opsin","type":"related"},{"name":"opsin","type":"related"},{"name":"red-sensitive opsin","type":"related"},{"name":"retinaldehyde binding","type":"exact"},{"name":"short-wave-sensitive opsin","type":"related"},{"name":"violet-sensitive opsin","type":"related"},{"name":"vitamin A binding","type":"broad"}],"termid":"GO:0016918"}


id: GO:0061760
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.","definition_xrefs":["PMID:22470487","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"innate immune response","termid":"GO:0045087"},{"relation_name":"is_a","term_name":"defense response to fungus","termid":"GO:0050832"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"antifungal innate immune response","termid":"GO:0061760"}


id: GO:0090139
data:
  {"annotated_genes":["SJAG_00634"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[97931],"is_not":false,"summary":null,"term":"GO:0090139"}]},"cv_name":"biological_process","definition":"A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure.","definition_xrefs":["GOC:dph","GOC:ascb_2009","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome organization","termid":"GO:0051276"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00634":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mitochondrial chromosome packaging","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"mitochondrial DNA packaging","type":"exact"}],"termid":"GO:0090139","terms_by_termid":{"GO:0090139":null}}


id: PBO:0070068
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6atac small nuclear 25, pseudogene","termid":"PBO:0070068"}


id: PBO:0064523
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase III subunit D","termid":"PBO:0064523"}


id: PBO:0055318
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2746","termid":"PBO:0055318"}


id: PBO:0090196
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Ksp1","termid":"PBO:0090196"}


id: GO:0005780
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.","definition_xrefs":["GOC:jl","GOC:dos","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extrinsic component of organelle membrane","termid":"GO:0031312"},{"relation_name":"part_of","term_name":"peroxisomal membrane","termid":"GO:0005778"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005777"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005777","GO:0005737"],"is_obsolete":false,"name":"extrinsic component of intraperoxisomal membrane","synonyms":[{"name":"extrinsic to intraperoxisomal membrane","type":"exact"},{"name":"intra-peroxisomal peripheral membrane","type":"related"}],"termid":"GO:0005780"}


id: MONDO:0020200
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete conjunctival hemangioma or hemolymphangioma (obsolete MONDO:0020200)","secondary_identifiers":["Orphanet:98612"],"termid":"MONDO:0020200","xrefs":{"Monarch":{"xref_id":"0020200"}}}


id: PBO:0075170
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear ribonucleoprotein polypeptide E","termid":"PBO:0075170"}


id: PBO:0042251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"copper chaperone for superoxide dismutase","termid":"PBO:0042251"}


id: SO:0001228
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A modified RNA base in which the 5,6-dihydrouracil is bound to the ribose ring.","definition_xrefs":["RSC:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified_uridine","termid":"SO:0001277"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dihydrouridine","secondary_identifiers":["http://en.wikipedia.org/wiki/Dihydrouridine","RNAMOD:051"],"synonyms":[{"name":" D","type":"exact"}],"termid":"SO:0001228"}


id: GO:0015528
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).","definition_xrefs":["TC:2.A.1.1.9","TC:2.A.1.5.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate:proton symporter activity","termid":"GO:0005351"},{"relation_name":"is_a","term_name":"lactose transmembrane transporter activity","termid":"GO:0015155"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"lactose:proton symporter activity","synonyms":[{"name":"lactose, galactose:hydrogen symporter activity","type":"broad"},{"name":"lactose:hydrogen symporter activity","type":"exact"}],"termid":"GO:0015528"}


id: MOD:01932
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links two lysine residues with a carbon-nitrogen bond to form L-lysinonorleucine..","definition_xrefs":["PubMed:5879466","PubMed:5117030","PubMed:5817620","PubMed:6030254","RESID:AA0586"],"direct_ancestors":[{"relation_name":"is_a","term_name":"crosslinked residues with loss of ammonia","termid":"MOD:00946"},{"relation_name":"is_a","term_name":"crosslinked L-lysine residue","termid":"MOD:02051"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-lysinonorleucine","synonyms":[{"name":"(2S)-2-amino-6-([(5S)-5-amino-5-carboxypentyl]amino)hexanoic acid","type":"exact"},{"name":"(2S,2'S)-6,6'-iminobis(2-aminohexanoic acid)","type":"exact"},{"name":"6-(N6-L-lysino)-L-norleucine","type":"exact"},{"name":"L-lysinonorleucine","type":"exact"},{"name":"N6-[(5S)-5-amino-5-carboxypentyl]-L-lysine","type":"exact"},{"name":"lysinonorleucine","type":"exact"},{"name":"lysinorleucine [misspelling]","type":"exact"},{"name":"lysylnorleucine","type":"exact"}],"termid":"MOD:01932"}


id: MONDO:0013576
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Deficiencies in immunoglobulin (Ig) isotypes (including: isolated IgG subclass deficiency, IgG subclass deficiency with IgA deficiency and kappa chain deficiency) are primary immunodeficiencies that are often asymptomatic but can be characterized by recurrent, often pyogenic, sinopulmonary infections.","definition_xrefs":["Orphanet:183675"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn error of immunity","termid":"MONDO:0003778"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"recurrent infections associated with rare immunoglobulin isotypes deficiency","secondary_identifiers":["NANDO:2200719","OMIM:614102","UMLS:C3279824","MESH:C564131","GARD:17086","MEDGEN:481454"],"synonyms":[{"name":"IGKCD","type":"related"},{"name":"IMMUNOGLOBULIN kappa LIGHT chain deficiency","type":"related"},{"name":"IgG subclass deficiency with IgA subclass deficiency","type":"exact"},{"name":"isolated IgG subclass deficiency","type":"exact"},{"name":"kappa chain deficiency","type":"related"},{"name":"kappa light chain deficiency","type":"exact"},{"name":"kappa-chain deficiency","type":"exact"},{"name":"recurrent infections associated with rare immunoglobulin isotypes deficiency","type":"exact"},{"name":"selective IgG subclass deficiency","type":"related"}],"termid":"MONDO:0013576","xrefs":{"Monarch":{"xref_id":"0013576"}}}


id: PBO:0050437
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein L pseudogene 1","termid":"PBO:0050437"}


id: PR:Q10106
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A U3 small nucleolar RNA-associated protein 11 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00917"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U3 small nucleolar RNA-associated protein 11 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC18G6.06","secondary_identifiers":["UniProtKB:Q10106"],"synonyms":[{"name":"Spom972h-UTP11L","type":"exact"},{"name":"U3 snoRNA-associated protein 11 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10106"}


id: PBO:0074701
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 71A","termid":"PBO:0074701"}


id: GO:0060251
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of glial cell proliferation.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell population proliferation","termid":"GO:0042127"},{"relation_name":"regulates","term_name":"glial cell proliferation","termid":"GO:0014009"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of glial cell proliferation","termid":"GO:0060251"}


id: PBO:0078098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trafficking protein particle complex subunit 6A","termid":"PBO:0078098"}


id: MONDO:0018858
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Graham Little-Piccardi-Lassueur syndrome is a variant of lichen planopilaris characterized by the clinical triad of progressive cicatricial (scarring) alopecia of the scalp, follicular keratotic papules on glabrous skin, and variable alopecia of the axillae and groin.","definition_xrefs":["Orphanet:505"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alopecia","termid":"MONDO:0004907"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Graham Little-Piccardi-Lassueur syndrome","secondary_identifiers":["UMLS:C4273658","GARD:3195","ICD10CM:L66.1","MEDGEN:905915","SCTID:718215008"],"synonyms":[{"name":"Graham Little syndrome","type":"exact"},{"name":"Graham-Little-Piccardi-Lassueur syndrome","type":"related"},{"name":"Piccardi-Lassueur-Little syndrome","type":"exact"}],"termid":"MONDO:0018858","xrefs":{"Monarch":{"xref_id":"0018858"}}}


id: PBO:0087991
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-specific adenosine deaminase; deaminates adenosine-37 to inosine in tRNA-Ala","termid":"PBO:0087991"}


id: MONDO:0005198
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Intraepithelial neoplasia of the vulvar squamous epithelium. There is no evidence of invasion. This category includes vulvar high grade squamous intraepithelial lesion and vulvar intraepithelial neoplasia, differentiated type.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vulvar squamous neoplasm","termid":"MONDO:0002195"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vulvar intraepithelial neoplasia","secondary_identifiers":["NCIT:C4756","GARD:19876","MEDGEN:91093","UMLS:C0346210","Orphanet:137583","EFO:0002627"],"synonyms":[{"name":"VIN","type":"exact"},{"name":"intraepithelial neoplasia of the vulva","type":"exact"},{"name":"intraepithelial neoplasia of vulva","type":"exact"},{"name":"squamous vulvar intraepithelial neoplasia","type":"exact"},{"name":"vulva intraepithelial neoplasia","type":"exact"},{"name":"vulval intraepithelial neoplasia","type":"exact"},{"name":"vulvar intraepithelial tumor","type":"exact"},{"name":"vulvar intraepithelial tumour","type":"exact"}],"termid":"MONDO:0005198","xrefs":{"Monarch":{"xref_id":"0005198"}}}


id: PBO:0045241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DnaJ heat shock protein family (Hsp40) member C19 pseudogene 9","termid":"PBO:0045241"}


id: PR:G2TRR0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC336.16 gene.","definition_xrefs":["UniProtKB:G2TRR0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C336.16 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC336.16","synonyms":[{"name":"Spom972h-SPBC336.16","type":"exact"}],"termid":"PR:G2TRR0"}


id: PBO:0000703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase family or domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SR family","termid":"PBO:0000703"}


id: MONDO:1010645
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hemophilia B that occurs in horse.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hemophilia B, non-human animal","termid":"MONDO:1010075"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hemophilia B, horse","secondary_identifiers":["OMIA:000438-9796"],"termid":"MONDO:1010645","xrefs":{"Monarch":{"xref_id":"1010645"}}}


id: MONDO:0017873
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Ebola hemorrhagic fever (obsolete MONDO:0017873)","termid":"MONDO:0017873","xrefs":{"Monarch":{"xref_id":"0017873"}}}


id: PBO:0046684
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation termination factor 1 pseudogene 2","termid":"PBO:0046684"}


id: GO:0035169
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.","definition_xrefs":["PMID:8174791","PMID:11921077","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"larval lymph gland hemocyte differentiation","termid":"GO:0035168"},{"relation_name":"is_a","term_name":"plasmatocyte differentiation","termid":"GO:0042387"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lymph gland plasmatocyte differentiation","synonyms":[{"name":"lymph gland plasmatocyte cell differentiation","type":"exact"}],"termid":"GO:0035169"}


id: FYPO:0007377
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A  cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the medial cortex is observed there during interphase of the mitotic cell cycle.","definition_xrefs":["PomBase:mah","PMID:9679144"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein mislocalized to medial cortex during vegetative growth","termid":"FYPO:0003390"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000138","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"protein mislocalized to medial cortex during mitotic interphase","synonyms":[{"name":"ectopic protein localization to medial cortex during mitotic interphase","type":"exact"},{"name":"protein mislocalised to medial cortex during mitotic interphase during vegetative growth","type":"exact"},{"name":"protein mislocalized to medial cortex during interphase of mitotic cell cycle","type":"exact"}],"termid":"FYPO:0007377"}


id: MONDO:0014952
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability-epilepsy-extrapyramidal syndrome","secondary_identifiers":["GARD:13474","UMLS:C4310683","Orphanet:468620","OMIM:617171","MEDGEN:934650"],"synonyms":[{"name":"DYSEIDD","type":"related"},{"name":"dyskinesia, seizures, and intellectual developmental disorder","type":"related"},{"name":"neurodevelopmental disorder with hypotonia, impaired expressive language, and with or without seizures","type":"exact"}],"termid":"MONDO:0014952","xrefs":{"Monarch":{"xref_id":"0014952"}}}


id: GO:0032826
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune effector process","termid":"GO:0002697"},{"relation_name":"is_a","term_name":"regulation of natural killer cell differentiation","termid":"GO:0032823"},{"relation_name":"regulates","term_name":"natural killer cell differentiation involved in immune response","termid":"GO:0002325"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of natural killer cell differentiation involved in immune response","synonyms":[{"name":"regulation of NK cell differentiation during immune response","type":"related"},{"name":"regulation of natural killer cell development involved in immune response","type":"related"},{"name":"regulation of natural killer cell differentiation during immune response","type":"related"}],"termid":"GO:0032826"}


id: GO:0039564
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2).","definition_xrefs":["PMID:32699158"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT activity","termid":"GO:0039562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT2 activity","secondary_identifiers":["VZ:257"],"synonyms":[{"name":"disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity","type":"narrow"},{"name":"inhibition by virus of host STAT2 activity","type":"narrow"},{"name":"inhibition of host STAT2 by virus","type":"narrow"},{"name":"suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity","type":"narrow"},{"name":"suppression by virus of host STAT2 activity","type":"narrow"}],"termid":"GO:0039564"}


id: FYPO:0007212
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at heterochromatin islands is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased chromatin silencing","termid":"FYPO:0002353"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0006551"],"is_obsolete":false,"name":"decreased chromatin silencing at heterochromatin island","synonyms":[{"name":"decreased chromatin silencing at heterochromatin island during mitotic cell cycle","type":"related"},{"name":"decreased chromatin silencing at heterochromatin island during vegetative growth","type":"exact"},{"name":"reduced chromatin silencing at heterochromatin island","type":"exact"}],"termid":"FYPO:0007212"}


id: GO:0072185
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metanephric mesenchyme development","termid":"GO:0072075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric cap development","termid":"GO:0072185"}


id: PBO:0060339
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myosin VC","termid":"PBO:0060339"}


id: PBO:0076421
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TATA-box binding protein associated factor 9 pseudogene 2","termid":"PBO:0076421"}


id: PBO:0056266
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mastermind like transcriptional coactivator 2","termid":"PBO:0056266"}


id: GO:1905551
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.","definition_xrefs":["GO_REF:0000058","PMID:22768340","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein localization","termid":"GO:1903828"},{"relation_name":"is_a","term_name":"regulation of protein localization to endoplasmic reticulum","termid":"GO:1905550"},{"relation_name":"negatively_regulates","term_name":"protein localization to endoplasmic reticulum","termid":"GO:0070972"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of protein localization to endoplasmic reticulum","synonyms":[{"name":"down regulation of protein localisation in endoplasmic reticulum","type":"exact"},{"name":"down regulation of protein localization in ER","type":"exact"},{"name":"down regulation of protein localization in endoplasmic reticulum","type":"exact"},{"name":"down regulation of protein localization to endoplasmic reticulum","type":"exact"},{"name":"down-regulation of protein localisation in endoplasmic reticulum","type":"exact"},{"name":"down-regulation of protein localization in ER","type":"exact"},{"name":"down-regulation of protein localization in endoplasmic reticulum","type":"exact"},{"name":"down-regulation of protein localization to endoplasmic reticulum","type":"exact"},{"name":"downregulation of protein localisation in endoplasmic reticulum","type":"exact"},{"name":"downregulation of protein localization in ER","type":"exact"},{"name":"downregulation of protein localization in endoplasmic reticulum","type":"exact"},{"name":"downregulation of protein localization to endoplasmic reticulum","type":"exact"},{"name":"inhibition of protein localisation in endoplasmic reticulum","type":"narrow"},{"name":"inhibition of protein localization in ER","type":"narrow"},{"name":"inhibition of protein localization in endoplasmic reticulum","type":"narrow"},{"name":"inhibition of protein localization to endoplasmic reticulum","type":"narrow"},{"name":"negative regulation of protein localisation in endoplasmic reticulum","type":"exact"},{"name":"negative regulation of protein localization in ER","type":"exact"},{"name":"negative regulation of protein localization in endoplasmic reticulum","type":"exact"}],"termid":"GO:1905551"}


id: GO:0047105
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate.","definition_xrefs":["EC:1.2.1.47","MetaCyc:1.2.1.47-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","termid":"GO:0016620"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"4-trimethylammoniobutyraldehyde dehydrogenase activity","secondary_identifiers":["Reactome:R-HSA-71260","RHEA:17985"],"synonyms":[{"name":"4-N-trimethylaminobutyraldehyde dehydrogenase activity","type":"related"},{"name":"4-trimethylaminobutyraldehyde dehydrogenase activity","type":"related"},{"name":"4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity","type":"related"}],"termid":"GO:0047105"}


id: GO:0045729
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes.","definition_xrefs":["PMID:9013127","ISBN:0198506732","PMID:2537493"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory burst","termid":"GO:0045730"},{"relation_name":"part_of","term_name":"single fertilization","termid":"GO:0007338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"respiratory burst at fertilization","synonyms":[{"name":"metabolic burst at fertilization","type":"exact"},{"name":"oxidative burst at fertilization","type":"exact"}],"termid":"GO:0045729"}


id: PBO:0059204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAS related GPR family member X11, pseudogene","termid":"PBO:0059204"}


id: MONDO:0026726
data:
  {"annotated_genes":["SJAG_04013","SJAG_00864"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85684,85685],"is_not":false,"summary":null,"term":"MONDO:0026726"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial nephrotic syndrome","termid":"MONDO:0002350"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00864":null,"SJAG_04013":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"nephrotic syndrome, type 20","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1678854","GARD:15285","OMIM:301028","UMLS:C5193011","DOID:0070357"],"synonyms":[{"name":"NEPHROTIC SYNDROME, TYPE 20","type":"related"},{"name":"NPHS20","type":"related"}],"termid":"MONDO:0026726","terms_by_termid":{"MONDO:0026726":null},"xrefs":{"Monarch":{"xref_id":"0026726"}}}


id: MONDO:1011270
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Diabetic cataract that occurs in degu.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diabetic cataract, non-human animal","termid":"MONDO:1010343"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diabetic cataract, degu","secondary_identifiers":["OMIA:001865-10160"],"termid":"MONDO:1011270","xrefs":{"Monarch":{"xref_id":"1011270"}}}


id: PBO:0044596
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DDB1 and CUL4 associated factor 4 like 2","termid":"PBO:0044596"}


id: GO:0102170
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 = capsidiol + 2 NADP + 2 H2O.","definition_xrefs":["EC:1.14.14.149","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"5-epi-aristolochene-1,3-dihydroxylase activity","secondary_identifiers":["RHEA:28226","MetaCyc:RXN-11908"],"termid":"GO:0102170"}


id: PBO:0113246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nucleolin, nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; binds to G-quadruplex DNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by lysine polyphosphorylation","termid":"PBO:0113246"}


id: GO:1904529
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of actin filament binding.","definition_xrefs":["GO_REF:0000059","GOC:TermGenie","PMID:24520051","GOC:als"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of actin filament binding (obsolete GO:1904529)","synonyms":[{"name":"regulation of F-actin binding","type":"exact"},{"name":"regulation of actin cross-linking activity","type":"related"}],"termid":"GO:1904529"}


id: PBO:0050226
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group nucleosomal binding domain 2 pseudogene 4","termid":"PBO:0050226"}


id: PBO:0068672
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4 small nuclear 53, pseudogene","termid":"PBO:0068672"}


id: FYECO:0000093
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which lithium ions were added to the assay buffer in excess compared to standard assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ ions","termid":"FYECO:0000030"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ Li ions","synonyms":[{"name":"lithium ions added","type":"exact"}],"termid":"FYECO:0000093"}


id: PBO:0005215
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane proteolipid Pmp31","termid":"PBO:0005215"}


id: PBO:0076461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transaldolase 1","termid":"PBO:0076461"}


id: GO:0033409
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A triplet codon-amino acid adaptor activity that recognizes a UAU codon.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triplet codon-amino acid adaptor activity","termid":"GO:0030533"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0060090"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0003723","GO:0060090"],"is_obsolete":false,"name":"UAU codon-amino acid adaptor activity","synonyms":[{"name":"TAT codon-amino acid adaptor activity","type":"exact"},{"name":"tyrosine tRNA","type":"related"}],"termid":"GO:0033409"}


id: GO:0062026
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.","definition_xrefs":["PMID:28007894"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of proteasomal ubiquitin-dependent protein catabolic process","termid":"GO:0032435"},{"relation_name":"is_a","term_name":"regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process","termid":"GO:0062025"},{"relation_name":"negatively_regulates","term_name":"SCF-dependent proteasomal ubiquitin-dependent protein catabolic process","termid":"GO:0031146"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0030163"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0030163"}],"interesting_parent_ids":["GO:0008150","GO:0030163"],"is_obsolete":false,"name":"negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process","termid":"GO:0062026"}


id: PBO:0003350
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"palmitoyl protein thioesterase-dolichol pyrophosphate phosphatase fusion 1","termid":"PBO:0003350"}


id: GO:0001546
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.","direct_ancestors":[{"relation_name":"is_a","term_name":"ovulation cycle process","termid":"GO:0022602"},{"relation_name":"is_a","term_name":"developmental growth","termid":"GO:0048589"},{"relation_name":"part_of","term_name":"ovarian follicle development","termid":"GO:0001541"},{"relation_name":"part_of","term_name":"multi-layer follicle stage","termid":"GO:0048162"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"preantral ovarian follicle growth","termid":"GO:0001546"}


id: MONDO:0012471
data:
  {"annotated_genes":["SJAG_01884"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84948],"is_not":false,"summary":null,"term":"MONDO:0012471"}]},"cv_name":"mondo","definition":"Any Aicardi-Goutieres syndrome in which the cause of the disease is a mutation in the RNASEH2C gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Aicardi-Goutieres syndrome","termid":"MONDO:0018866"},{"relation_name":"is_a","term_name":"RNASEH2C-related type 1 interferonopathy","termid":"MONDO:0700258"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01884":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0006025","MONDO:0005046"],"is_obsolete":false,"name":"Aicardi-Goutieres syndrome 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1835916","GARD:15479","MESH:C563683","MEDGEN:324389","NANDO:2200895","OMIM:610329"],"synonyms":[{"name":"AGS3","type":"related"},{"name":"Aicardi-Goutieres syndrome 3","type":"exact"},{"name":"Aicardi-Goutieres syndrome caused by mutation in RNASEH2C","type":"exact"},{"name":"Aicardi-Goutieres syndrome type 3","type":"exact"},{"name":"RNASEH2C -related Aicardi-Goutieres syndrome","type":"related"},{"name":"RNASEH2C Aicardi-Goutieres syndrome","type":"exact"}],"termid":"MONDO:0012471","terms_by_termid":{"MONDO:0012471":null},"xrefs":{"Monarch":{"xref_id":"0012471"}}}


id: PBO:0076771
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tudor domain containing 10","termid":"PBO:0076771"}


id: GO:1900569
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. Chanoclavine-I aldehyde is at a branching point in the biosynthetic pathways of fumigaclavine C and ergotamine.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ergot alkaloid biosynthetic process","termid":"GO:0035837"},{"relation_name":"is_a","term_name":"aldehyde biosynthetic process","termid":"GO:0046184"},{"relation_name":"is_a","term_name":"olefinic compound biosynthetic process","termid":"GO:0120255"},{"relation_name":"is_a","term_name":"chanoclavine-I aldehyde metabolic process","termid":"GO:1900567"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"chanoclavine-I aldehyde biosynthetic process","synonyms":[{"name":"chanoclavine-I aldehyde anabolism","type":"exact"},{"name":"chanoclavine-I aldehyde biosynthesis","type":"exact"},{"name":"chanoclavine-I aldehyde formation","type":"exact"},{"name":"chanoclavine-I aldehyde synthesis","type":"exact"}],"termid":"GO:1900569"}


id: PBO:0075607
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPON1 antisense RNA 1","termid":"PBO:0075607"}


id: GO:0141025
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The attachment of a symbiont to its host by binding to a glycoprotein on the host cell surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:12010488","PMID:15487949","PMID:17630833","PMID:29184850"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adhesion of symbiont to host cell","termid":"GO:0044650"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"adhesion of symbiont to host cell surface via host glycoprotein","termid":"GO:0141025"}


id: PBO:0066998
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA component of signal recognition particle 7SL2","termid":"PBO:0066998"}


id: PBO:0041153
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"basic transcription factor 3 pseudogene 8","termid":"PBO:0041153"}


id: PBO:0071904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPS3A pseudogene 42","termid":"PBO:0071904"}


id: GO:0004109
data:
  {"annotated_genes":["SJAG_04944"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[79706],"is_not":false,"summary":null,"term":"GO:0004109"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: coproporphyrinogen III + 2 H+ + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX.","definition_xrefs":["EC:1.3.3.3","RHEA:18257"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor","termid":"GO:0016634"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04944":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"coproporphyrinogen oxidase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:RXN0-1461","KEGG_REACTION:R03220","Reactome:R-HSA-189421"],"synonyms":[{"name":"coprogen oxidase activity","type":"exact"},{"name":"coproporphyrinogen-III oxidase activity","type":"exact"},{"name":"coproporphyrinogen:oxygen oxidoreductase (decarboxylating)","type":"related"},{"name":"coproporphyrinogenase activity","type":"exact"}],"termid":"GO:0004109","terms_by_termid":{"GO:0004109":null}}


id: PBO:0051470
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable (I)-68 (pseudogene)","termid":"PBO:0051470"}


id: MONDO:0007209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Weismann-Netter syndrome is a rare, genetic, primary, bent bone dysplasia characterized by anterior diaphyseal bowing of the tibia and fibula, broadening of the fibula, posterior cortical thickening of both bones and short stature. Additional skeletal abnormalities include scoliosis with marked lumbar lordosis, horizontal sacrum and square iliac wings and/or, less frequently, vertebral malformations, abnormal shape of the clavicles and ribs, calvarial hyperostosis and delayed eruption of permanent teeth. Delayed ambulation is also frequently associated.","definition_xrefs":["Orphanet:3344"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bent bone dysplasia","termid":"MONDO:0019698"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Weismann-Netter syndrome","secondary_identifiers":["NORD:1843","OMIM:112350","MESH:C537082","MEDGEN:350610","GARD:5232","SCTID:715532007","UMLS:C1862172","icd11.foundation:180927608"],"synonyms":[{"name":"Toxopachyosteose Diaphysaire Tibio-Peroniere","type":"related"},{"name":"WEISMANN-NETTER syndrome","type":"exact"},{"name":"WNS","type":"exact"},{"name":"Weismann Netter Stuhl Syndrome","type":"exact"},{"name":"Weismann Netter syndrome","type":"exact"},{"name":"Weismann-Netter syndrome","type":"exact"},{"name":"Weismann-Netter-Stuhl syndrome","type":"exact"},{"name":"anterior bowing of legs with dwarfism","type":"exact"},{"name":"bowing of legs, anterior with dwarfism","type":"related"},{"name":"bowing of legs, anterior, with dwarfism","type":"related"}],"termid":"MONDO:0007209","xrefs":{"Monarch":{"xref_id":"0007209"}}}


id: GO:0034651
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.","definition_xrefs":["GOC:mah","GOC:rl","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucocorticoid biosynthetic process","termid":"GO:0006704"},{"relation_name":"is_a","term_name":"primary alcohol biosynthetic process","termid":"GO:0034309"},{"relation_name":"is_a","term_name":"cortisol metabolic process","termid":"GO:0034650"},{"relation_name":"is_a","term_name":"ketone biosynthetic process","termid":"GO:0042181"},{"relation_name":"is_a","term_name":"olefinic compound biosynthetic process","termid":"GO:0120255"},{"relation_name":"is_a","term_name":"tertiary alcohol biosynthetic process","termid":"GO:1902645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006629"],"is_obsolete":false,"name":"cortisol biosynthetic process","synonyms":[{"name":"cortisol anabolism","type":"narrow"},{"name":"cortisol biosynthesis","type":"exact"},{"name":"cortisol formation","type":"exact"},{"name":"cortisol synthesis","type":"exact"}],"termid":"GO:0034651"}


id: PBO:0078874
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transient receptor potential cation channel subfamily M member 8","termid":"PBO:0078874"}


id: PBO:0081951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNRF3 antisense RNA 1","termid":"PBO:0081951"}


id: PBO:0071961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S6 kinase A2","termid":"PBO:0071961"}


id: PBO:0072267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S21 pseudogene 5","termid":"PBO:0072267"}


id: GO:0047180
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA.","definition_xrefs":["RHEA:22856","EC:2.3.1.150"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acetyltransferase activity","termid":"GO:0016413"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016746","GO:0003674"],"is_obsolete":false,"name":"salutaridinol 7-O-acetyltransferase activity","secondary_identifiers":["KEGG_REACTION:R04723","MetaCyc:2.3.1.150-RXN"],"synonyms":[{"name":"acetyl-CoA:salutaridinol 7-O-acetyltransferase activity","type":"related"}],"termid":"GO:0047180"}


id: MONDO:1011344
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Perinatal disease that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human animal disease","termid":"MONDO:0005583"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"perinatal disease, non-human animal","termid":"MONDO:1011344","xrefs":{"Monarch":{"xref_id":"1011344"}}}


id: FYPO:0005211
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during anaphase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to mitotic spindle pole body during mitosis","termid":"FYPO:0002822"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased protein localization to mitotic spindle pole body during anaphase","synonyms":[{"name":"decreased protein localisation to mitotic spindle pole body during anaphase","type":"exact"},{"name":"decreased protein localization to mitotic SPB during anaphase","type":"exact"},{"name":"decreased protein localization to mitotic spindle pole body during mitotic anaphase","type":"exact"},{"name":"decreased protein localization to spindle pole body during anaphase during vegetative growth","type":"exact"},{"name":"reduced protein localization to mitotic spindle pole body during anaphase","type":"exact"}],"termid":"FYPO:0005211"}


id: PBO:0049999
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone cell cycle regulator","termid":"PBO:0049999"}


id: MONDO:0017821
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete functioning pituitary adenoma (obsolete MONDO:0017821)","termid":"MONDO:0017821","xrefs":{"Monarch":{"xref_id":"0017821"}}}


id: PBO:0056256
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MALL pseudogene 1","termid":"PBO:0056256"}


id: GO:0008995
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.","definition_xrefs":["PMID:16854990","PMID:10722715"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA nuclease activity","termid":"GO:0004540"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0140098"}],"interesting_parent_ids":["GO:0003824","GO:0016788","GO:0140098","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"ribonuclease E activity","secondary_identifiers":["MetaCyc:3.1.26.12-RXN"],"termid":"GO:0008995"}


id: PBO:0083697
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated","termid":"PBO:0083697"}


id: GO:0045015
data:
  {"annotated_genes":["SJAG_02418"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[113375],"is_not":false,"summary":null,"term":"GO:0045015"}]},"cv_name":"molecular_function","definition":"Binding to a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.","definition_xrefs":["PMID:1327759"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ER retention sequence binding","termid":"GO:0046923"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02418":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005048"}],"interesting_parent_ids":["GO:0005048","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"HDEL sequence binding","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"HDEL receptor activity","type":"narrow"}],"termid":"GO:0045015","terms_by_termid":{"GO:0045015":null}}


id: GO:0000366
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.","definition_xrefs":["PMID:11726664","PMID:12110900","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA trans splicing, via spliceosome","termid":"GO:0000365"},{"relation_name":"is_a","term_name":"alternative mRNA splicing, via spliceosome","termid":"GO:0000380"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0016071"}],"interesting_parent_ids":["GO:0010467","GO:0016071","GO:0008150"],"is_obsolete":false,"name":"mRNA alternative trans-splicing","synonyms":[{"name":"intergenic mRNA trans splicing","type":"exact"},{"name":"intergenic nuclear mRNA trans splicing","type":"exact"}],"termid":"GO:0000366"}


id: PBO:0046332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ENOX1 antisense RNA 2","termid":"PBO:0046332"}


id: PBO:0053659
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 836","termid":"PBO:0053659"}


id: MONDO:0006096
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An endometrial hyperplasia characterized by cytologic and architectural changes which may lead to endometrial carcinoma. Despite the atypical features and possible course, there is debate on whether to consider this a neoplasm. The relationship with endometrial intraepithelial neoplasia is also unclear.","definition_xrefs":["NCIT:C4654"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endometrial disorder","termid":"MONDO:0000931"},{"relation_name":"is_a","term_name":"hyperplasia","termid":"MONDO:0005043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atypical endometrial hyperplasia","secondary_identifiers":["MEDGEN:138105","UMLS:C0349579","EFO:1000098","ICD9:621.33","SCTID:277158007"],"synonyms":[{"name":"atypical hyperplasia of endometrium","type":"exact"},{"name":"atypical hyperplasia of the endometrium","type":"exact"},{"name":"endometrial hyperplasia with atypia","type":"exact"}],"termid":"MONDO:0006096","xrefs":{"Monarch":{"xref_id":"0006096"}}}


id: GO:0039710
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome.","definition_xrefs":["VZ:1950"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic capsid assembly","termid":"GO:0039709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cytoplasmic icosahedral capsid assembly","termid":"GO:0039710"}


id: GO:0102434
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.","definition_xrefs":["PMID:20959559","PMID:18245455","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016829","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"pterin-4alpha-carbinolamine dehydratase activity","secondary_identifiers":["MetaCyc:RXN-13908"],"termid":"GO:0102434"}


id: PBO:0046442
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EPN2 antisense RNA 1","termid":"PBO:0046442"}


id: FYPO:0006096
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to actin cytoskeleton during vegetative growth","termid":"FYPO:0007578"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"abnormal protein localization to actin cable","synonyms":[{"name":"abnormal protein localisation to actin cable","type":"exact"},{"name":"abnormal protein localization to actin cable during mitotic cell cycle","type":"related"},{"name":"abnormal protein localization to actin cable during vegetative growth","type":"exact"},{"name":"abnormal protein localization to formin-nucleated actin cable","type":"exact"}],"termid":"FYPO:0006096"}


id: GO:2000400
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of thymocyte aggregation.","definition_xrefs":["GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of leukocyte cell-cell adhesion","termid":"GO:1903039"},{"relation_name":"is_a","term_name":"regulation of thymocyte aggregation","termid":"GO:2000398"},{"relation_name":"positively_regulates","term_name":"thymocyte aggregation","termid":"GO:0071594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"positive regulation of thymocyte aggregation","synonyms":[{"name":"positive regulation of T cell precursor aggregation","type":"exact"},{"name":"positive regulation of immature T cell aggregation","type":"related"},{"name":"positive regulation of immature T-cell aggregation","type":"related"},{"name":"positive regulation of immature T-lymphocyte aggregation","type":"exact"},{"name":"positive regulation of thymic lymphocyte aggregation","type":"exact"}],"termid":"GO:2000400"}


id: GO:0052008
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which an organism effects a change that impairs the structure or function of a host cellular anatomical structure. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated disruption of host anatomical structure","termid":"GO:0052111"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated disruption of host cellular anatomical structure","synonyms":[{"name":"catabolism of host cellular component by organism","type":"exact"},{"name":"catabolism of host structural constituent by organism","type":"exact"},{"name":"cytopathogenic effect","type":"related"},{"name":"degradation of host cellular component by organism","type":"exact"},{"name":"disassembly by organism of host cellular component","type":"exact"},{"name":"disassembly by symbiont of host cellular component","type":"related"},{"name":"disruption by symbiont of host cellular component","type":"exact"},{"name":"symbiont-mediated disruption of host cellular anatomical entity","type":"exact"},{"name":"symbiont-mediated disruption of host cellular component","type":"broad"}],"termid":"GO:0052008"}


id: GO:0055083
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell.","definition_xrefs":["GOC:ai","GOC:jid","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete monovalent inorganic anion homeostasis (obsolete GO:0055083)","termid":"GO:0055083"}


id: MONDO:0007190
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukemia, chronic lymphocytic, susceptibility to, 2","secondary_identifiers":["UMLS:C1868683","MEDGEN:358385","OMIM:109543"],"synonyms":[{"name":"B-cell malignancy, low-grade","type":"related"},{"name":"Clls2","type":"related"},{"name":"disrupted in B-cell malignancy","type":"related"},{"name":"leukemia, chronic lymphocytic, B-cell","type":"related"},{"name":"leukemia, chronic lymphocytic, susceptibility to, 2","type":"exact"},{"name":"leukemia, chronic lymphocytic, susceptibility to, type 2","type":"exact"}],"termid":"MONDO:0007190","xrefs":{"Monarch":{"xref_id":"0007190"}}}


id: GO:0061241
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nephron epithelium development","termid":"GO:0072009"},{"relation_name":"is_a","term_name":"mesonephric epithelium development","termid":"GO:0072163"},{"relation_name":"part_of","term_name":"mesonephric nephron development","termid":"GO:0061215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric nephron epithelium development","termid":"GO:0061241"}


id: FYPO:0006317
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased during the second meiotic nuclear division.","definition_xrefs":["PMID:29259000","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to meiotic spindle pole body","termid":"FYPO:0002772"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000138","FYPO:0000054","FYPO:0005447","FYPO:0001985","FYPO:0000631"],"is_obsolete":false,"name":"decreased protein localization to meiotic spindle pole body during meiosis II","synonyms":[{"name":"decreased protein localisation to meiotic spindle pole body during meiosis II","type":"exact"},{"name":"decreased protein localization to meiotic SPB during meiosis II","type":"exact"},{"name":"decreased protein localization to meiotic spindle pole body during second meiotic nuclear division","type":"exact"},{"name":"decreased protein localization to spindle pole body during meiosis II","type":"exact"},{"name":"reduced protein localization to meiotic spindle pole body during meiosis II","type":"exact"}],"termid":"FYPO:0006317"}


id: FYPO:0005555
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin loading is decreased during the mitotic cell cycle. Cohesin loading is the topological linking of a cohesin ring complex to chromatin.","definition_xrefs":["PomBase:mah","GO:0061780"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal regulation of molecular function","termid":"FYPO:0000682"},{"relation_name":"is_a","term_name":"decreased protein localization to chromatin during vegetative growth","termid":"FYPO:0002909"},{"relation_name":"is_a","term_name":"abnormal cohesin loading","termid":"FYPO:0006479"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000641","FYPO:0005447","FYPO:0000002","FYPO:0000138","FYPO:0001320","FYPO:0000631"],"is_obsolete":false,"name":"decreased mitotic cohesin loading","synonyms":[{"name":"decreased cohesin loading during mitotic cell cycle","type":"exact"},{"name":"decreased cohesin loading during vegetative growth","type":"exact"},{"name":"decreased mitotic cohesin association with chromatin","type":"exact"},{"name":"decreased mitotic cohesin localization to chromatin","type":"exact"},{"name":"reduced mitotic cohesin loading","type":"exact"}],"termid":"FYPO:0005555"}


id: GO:0072060
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"collecting duct development","termid":"GO:0072044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"outer medullary collecting duct development","termid":"GO:0072060"}


id: MONDO:0000388
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete anonychia congenita (obsolete MONDO:0000388)","synonyms":[{"name":"hyponychia congenita","type":"exact"}],"termid":"MONDO:0000388","xrefs":{"Monarch":{"xref_id":"0000388"}}}


id: GO:0007615
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.","definition_xrefs":["PMID:17088531","PMID:15143285"],"direct_ancestors":[{"relation_name":"is_a","term_name":"memory","termid":"GO:0007613"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"anesthesia-resistant memory","termid":"GO:0007615"}


id: MONDO:0015991
data:
  {"annotated_genes":["SJAG_04577"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86831],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008988"}]},"cv_name":"mondo","definition":"Citrullinemia is an autosomal recessively inherited disorder of urea cycle metabolism and ammonia detoxification characterized by elevated concentrations of serum citrulline and ammonia. The disease presents with a large range of manifestations including neonatal hyperammonemic encephalopathy with lethargy, seizures and coma; hepatic dysfunction in all age groups; episodes of hyperammonemia and neuropsychiatric symptoms in children or adults, or, can be asymptomatic in some cases (detected in newborn screening programs). Citrullinemia is divided into two main groups that are encoded by different genes: citrullinemia type I (comprised of acute neonatal citrullinemia type I and adult-onset citrullinemia type I) and citrin deficiency (comprised of adult-onset citrullinemia type II and neonatal intrahepatic cholestasis due to citrin deficiency).","definition_xrefs":["Orphanet:187"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urea cycle disorder","termid":"MONDO:0004739"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04577":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"citrullinemia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C84639","OMIMPS:215700","SCTID:124711003","UMLS:C0175683","MEDGEN:104491","DOID:9273","GARD:16522","icd11.foundation:640937125","MESH:D020159","ICD10CM:E72.23"],"synonyms":[{"name":"ass deficiency","type":"narrow"},{"name":"deficiency of citrulline-aspartate ligase","type":"exact"}],"termid":"MONDO:0015991","terms_by_termid":{"MONDO:0008988":null},"xrefs":{"Monarch":{"xref_id":"0015991"}}}


id: PBO:0034052
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_vector","termid":"PBO:0034052"}


id: PBO:0041745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CAMTA1 antisense RNA 2","termid":"PBO:0041745"}


id: GO:0003721
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template.","definition_xrefs":["PMID:11812242"],"gene_count":0,"genotype_count":0,"name":"obsolete telomerase RNA reverse transcriptase activity (obsolete GO:0003721)","synonyms":[{"name":"telomerase, catalyst","type":"exact"}],"termid":"GO:0003721"}


id: GO:0033459
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A triplet codon-amino acid adaptor activity that recognizes a GAA codon.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triplet codon-amino acid adaptor activity","termid":"GO:0030533"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0060090","GO:0005488","GO:0003723"],"is_obsolete":false,"name":"GAA codon-amino acid adaptor activity","synonyms":[{"name":"glutamic acid tRNA","type":"related"}],"termid":"GO:0033459"}


id: MONDO:0018174
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary glaucoma is a clinically diverse group of rare eye disorders with genetic predisposition characterized by elevated intraocular pressure (IOP) and glaucomatous changes of the optic nerve head, leading to field defects, visual loss and blindness. Hereditary glaucoma can be sub-classified as primary (congenital glaucoma, juvenile glaucoma) or secondary according to the presence or absence of systemic or other ocular anomalies (iridogoniodysgenesis, Stickler syndrome, Coats syndrome). The clinical presentation is variable and is based on age, severity of glaucoma, presence of ocular abnormalities and development of secondary IOP related abnormalities.","definition_xrefs":["Orphanet:359"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete non-syndromic developmental defect of the eye (obsolete MONDO:0015217)","termid":"MONDO:0015217"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"glaucoma","termid":"MONDO:0005041"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"hereditary glaucoma","secondary_identifiers":["GARD:2486","UMLS:C3711383","MESH:C580055","MEDGEN:777991"],"synonyms":[{"name":"glaucoma, hereditary","type":"related"},{"name":"hereditary glaucoma (disease)","type":"exact"}],"termid":"MONDO:0018174","xrefs":{"Monarch":{"xref_id":"0018174"}}}


id: GO:0072176
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tube development","termid":"GO:0035295"},{"relation_name":"is_a","term_name":"kidney epithelium development","termid":"GO:0072073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"nephric duct development","termid":"GO:0072176"}


id: PBO:0079180
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis specific protein Y-linked 9","termid":"PBO:0079180"}


id: PBO:0088978
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin-8 family plus-end directed microtubule motor Klp5","termid":"PBO:0088978"}


id: PBO:0042124
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 197","termid":"PBO:0042124"}


id: PBO:0027278
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_UV-damage_excision_repair_during_mitotic_G1_phase","termid":"PBO:0027278"}


id: FYPO:0007035
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing 5-fluorouracil.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002060"}],"interesting_parent_ids":["FYPO:0002058","FYPO:0000139","FYPO:0002057","FYPO:0000257","FYPO:0002060","FYPO:0000003"],"is_obsolete":false,"name":"normal growth on 5-fluorouracil","synonyms":[{"name":"normal cell population growth in presence of 5-fluorouracil","type":"exact"},{"name":"normal cell population growth on 5-FU","type":"exact"},{"name":"normal cell population growth on 5-fluorouracil","type":"exact"},{"name":"normal vegetative cell population growth on 5-fluorouracil","type":"exact"}],"termid":"FYPO:0007035"}


id: GO:0032423
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of mismatch repair.","definition_xrefs":["GOC:vk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of DNA repair","termid":"GO:0006282"},{"relation_name":"regulates","term_name":"mismatch repair","termid":"GO:0006298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"regulates","termid":"GO:0006281"}],"interesting_parent_ids":["GO:0006259","GO:0006281","GO:0008150"],"is_obsolete":false,"name":"regulation of mismatch repair","termid":"GO:0032423"}


id: PBO:0113057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of KEOPS complex with Kae1p, Cgi121p, Pcc1p, and Gon7p; provides the ATPase and GTPase activities of the complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; mutation is functionally complemented by human ortholog TP53RK","termid":"PBO:0113057"}


id: MONDO:1011579
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nonspherocytic hemolytic anemia that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nonspherocytic hemolytic anemia, non-human animal","termid":"MONDO:1011407"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nonspherocytic hemolytic anemia, dog","secondary_identifiers":["OMIA:000433-9615"],"termid":"MONDO:1011579","xrefs":{"Monarch":{"xref_id":"1011579"}}}


id: GO:0051486
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isopentenyl diphosphate biosynthetic process, mevalonate pathway","termid":"GO:0019287"},{"relation_name":"part_of","term_name":"terpenoid biosynthetic process, mevalonate-dependent","termid":"GO:0051485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"part_of","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0044281","GO:0006629","GO:0055086","GO:0006790","GO:0008150"],"is_obsolete":false,"name":"isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process","synonyms":[{"name":"isopentenyl diphosphate anabolism, mevalonate pathway, during terpenoid anabolism","type":"related"},{"name":"isopentenyl diphosphate biosynthetic process, mevalonate pathway, during terpenoid biosynthetic process","type":"related"},{"name":"isopentenyl diphosphate formation, mevalonate pathway, during terpenoid biosynthesis","type":"related"},{"name":"isopentenyl diphosphate formation, mevalonate pathway, during terpenoid formation","type":"related"},{"name":"isopentenyl diphosphate synthesis, mevalonate pathway, during terpenoid synthesis","type":"related"}],"termid":"GO:0051486"}


id: PBO:0061882
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oocyte secreted protein family member 4B","termid":"PBO:0061882"}


id: PBO:0057703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1290","termid":"PBO:0057703"}


id: PBO:0046820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FA core complex associated protein 24","termid":"PBO:0046820"}


id: PBO:0043698
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 5B pseudogene 4","termid":"PBO:0043698"}


id: GO:0017003
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The covalent linkage of heme and a protein.","definition_xrefs":["GOC:ma"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-tetrapyrrole linkage","termid":"GO:0017006"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein-heme linkage","synonyms":[{"name":"protein-haem linkage","type":"exact"}],"termid":"GO:0017003"}


id: PBO:0028377
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_xanthine_DNA_N-glycosylase_activity","termid":"PBO:0028377"}


id: MONDO:0004990
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Subsets of breast carcinoma defined by expression of genes characteristic of luminal epithelial cells.","definition_xrefs":["NCIT:C53555","NCIT:C53554"],"direct_ancestors":[{"relation_name":"is_a","term_name":"breast carcinoma by gene expression profile","termid":"MONDO:0006116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"breast tumor luminal A or B","secondary_identifiers":["DOID:0060548","EFO:0000306"],"synonyms":[{"name":"breast tumor luminal","type":"exact"},{"name":"breast tumour luminal","type":"exact"},{"name":"luminal breast cancer","type":"exact"},{"name":"luminal breast carcinoma","type":"related"}],"termid":"MONDO:0004990","xrefs":{"Monarch":{"xref_id":"0004990"}}}


id: GO:0016423
data:
  {"annotated_genes":["SJAG_04181","SJAG_00886","SJAG_00255","SJAG_04993","SJAG_04680","SJAG_01269"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[65668],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106340"},{"annotations":[62952],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0160102"},{"annotations":[61024],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0160104"},{"annotations":[66778],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052906"},{"annotations":[71337],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008176"},{"annotations":[58525],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052905"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + guanosine in tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.","definition_xrefs":["GOC:go-curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA methyltransferase activity","termid":"GO:0008175"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00255":null,"SJAG_00886":null,"SJAG_01269":null,"SJAG_04181":null,"SJAG_04680":null,"SJAG_04993":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140101"}],"interesting_parent_ids":["GO:0140098","GO:0016741","GO:0140101","GO:0016740","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"tRNA (guanine) methyltransferase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000003":null,"GO_REF:0000033":null},"secondary_identifiers":["GO:0016424"],"synonyms":[{"name":"tRNA (guanosine) methyltransferase activity","type":"exact"}],"termid":"GO:0016423","terms_by_termid":{"GO:0008176":null,"GO:0052905":null,"GO:0052906":null,"GO:0106340":null,"GO:0160102":null,"GO:0160104":null}}


id: PBO:0059758
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO3 pseudogene 32","termid":"PBO:0059758"}


id: MONDO:0015575
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Rare bacterial infectious disease.","gene_count":0,"genotype_count":0,"name":"obsolete rare bacterial infectious disease (obsolete MONDO:0015575)","secondary_identifiers":["Orphanet:163582"],"synonyms":[{"name":"rare bacterial infectious disease","type":"exact"}],"termid":"MONDO:0015575","xrefs":{"Monarch":{"xref_id":"0015575"}}}


id: MONDO:0006950
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the retinal vasculature with various causes including infectious disease; lupus erythematosus, systemic; multiple sclerosis; behcet syndrome; and chorioretinitis.","definition_xrefs":["MESH:D031300"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinal vascular disorder","termid":"MONDO:0002311"},{"relation_name":"is_a","term_name":"retinitis","termid":"MONDO:0002708"},{"relation_name":"is_a","term_name":"vasculitis","termid":"MONDO:0018882"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"retinal vasculitis","secondary_identifiers":["DOID:11563","UMLS:C0152026","MEDGEN:57503","MedDRA:10038905","icd11.foundation:1863208483","ICD9:362.18","EFO:1001156","SCTID:77628002"],"synonyms":[{"name":"retinal vasculitis","type":"exact"}],"termid":"MONDO:0006950","xrefs":{"Monarch":{"xref_id":"0006950"}}}


id: PBO:0084433
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAL-activator protein; part of complex locus MAL1; nonfunctional in genomic reference strain S288C","termid":"PBO:0084433"}


id: GO:0098963
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dendritic transport","termid":"GO:0098935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"dendritic transport of messenger ribonucleoprotein complex","synonyms":[{"name":"dendritic transport of mRNA RNP complex","type":"exact"}],"termid":"GO:0098963"}


id: GO:0014905
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.","definition_xrefs":["CL:0000056","GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myoblast fusion","termid":"GO:0007520"},{"relation_name":"part_of","term_name":"myotube differentiation involved in skeletal muscle regeneration","termid":"GO:0014908"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"myoblast fusion involved in skeletal muscle regeneration","termid":"GO:0014905"}


id: PBO:0017445
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-produced_by","termid":"PBO:0017445"}


id: SO:0000314
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A repeat where the same sequence is repeated in the same direction. Example: GCTGA-followed by-GCTGA.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"repeat_region","termid":"SO:0000657"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"direct_repeat","secondary_identifiers":["http://en.wikipedia.org/wiki/Direct_repeat"],"synonyms":[{"name":"INSDC_feature:repeat_region","type":"broad"},{"name":"INSDC_qualifier:direct","type":"exact"},{"name":"direct repeat","type":"exact"}],"termid":"SO:0000314"}


id: FYPO:0006397
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules become detached from the nuclear envelope (NE). Normally, some cytoplasmic microtubules are nucleated at the NE and remain attached.","definition_xrefs":["PomBase:mah","PMID:16481403"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal microtubule cytoskeleton morphology during vegetative growth","termid":"FYPO:0001418"},{"relation_name":"is_a","term_name":"abnormal cytoplasmic microtubules","termid":"FYPO:0004088"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002399"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002","FYPO:0002399","FYPO:0000054","FYPO:0005447"],"is_obsolete":false,"name":"cytoplasmic microtubules detached from nuclear envelope","synonyms":[{"name":"cytoplasmic microtubules detached from nuclear envelope during mitotic cell cycle","type":"related"},{"name":"cytoplasmic microtubules detached from nuclear envelope during vegetative growth","type":"exact"},{"name":"cytoplasmic microtubules dissociated from nuclear envelope","type":"exact"}],"termid":"FYPO:0006397"}


id: PBO:0091688
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Itsy-Bitsy Phosphatase","termid":"PBO:0091688"}


id: GO:0044298
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.","definition_xrefs":["GOC:ecd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"plasma membrane","termid":"GO:0005886"},{"relation_name":"part_of","term_name":"cell body","termid":"GO:0044297"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"cell body membrane","synonyms":[{"name":"cell soma membrane","type":"exact"}],"termid":"GO:0044298"}


id: PBO:0050063
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HLF transcription factor, PAR bZIP family member","termid":"PBO:0050063"}


id: GO:1905605
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.","definition_xrefs":["GO_REF:0000058","GOC:als","GOC:aruk","PMID:22524708","PMID:30280653","GOC:TermGenie","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of vascular permeability","termid":"GO:0043117"},{"relation_name":"is_a","term_name":"regulation of blood-brain barrier permeability","termid":"GO:1905603"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of blood-brain barrier permeability","synonyms":[{"name":"activation of maintenance of permeability of BBB","type":"narrow"},{"name":"activation of maintenance of permeability of blood-brain barrier","type":"narrow"},{"name":"positive regulation of BBB permeability","type":"exact"},{"name":"positive regulation of blood/brain barrier permeability","type":"exact"},{"name":"up-regulation of BBB permeability","type":"exact"},{"name":"up-regulation of blood-brain barrier permeability","type":"exact"},{"name":"up-regulation of blood/brain barrier permeability","type":"exact"},{"name":"upregulation of BBB permeability","type":"exact"},{"name":"upregulation of blood-brain barrier permeability","type":"exact"},{"name":"upregulation of blood/brain barrier permeability","type":"exact"}],"termid":"GO:1905605"}


id: PBO:0082020
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zyg-11 family member A, cell cycle regulator","termid":"PBO:0082020"}


id: PBO:0072507
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein SA pseudogene 36","termid":"PBO:0072507"}


id: PBO:0072520
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein SA pseudogene 49","termid":"PBO:0072520"}


id: MONDO:0024294
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Skin diseases caused by bacteria, fungi, parasites, or viruses.","definition_xrefs":["MESH:D012874"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin disorder","termid":"MONDO:0005093"},{"relation_name":"is_a","term_name":"infectious disease","termid":"MONDO:0005550"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"skin disorder caused by infection","synonyms":[{"name":"disease, infectious skin","type":"related"},{"name":"diseases, infectious skin","type":"related"},{"name":"infectious skin disease","type":"related"},{"name":"infectious skin diseases","type":"related"},{"name":"skin disease, infectious","type":"related"}],"termid":"MONDO:0024294","xrefs":{"Monarch":{"xref_id":"0024294"}}}


id: PBO:0015712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTP cyclohydrolase I involved in 7,8-dihydroneopterin 3'-triphosphate biosynthesis (predicted)","termid":"PBO:0015712"}


id: FYPO:0007329
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured at transfer RNA genes in a cell is greater than normal. The number, extent, or both of damage sites may be increased.","definition_xrefs":["PomBase:mah","PMID:31833215"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased DNA damage during vegetative growth","termid":"FYPO:0003547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002"],"is_obsolete":false,"name":"increased DNA damage at tRNA genes","synonyms":[{"name":"increased DNA damage at tRNA genes during mitotic cell cycle","type":"related"},{"name":"increased DNA damage at tRNA genes during vegetative growth","type":"exact"},{"name":"increased DNA damage at transfer RNA genes","type":"exact"},{"name":"increased number of DNA lesions at tRNA genes during vegetative growth","type":"related"}],"termid":"FYPO:0007329"}


id: MONDO:0013671
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"coronary artery disorder","termid":"MONDO:0005010"},{"relation_name":"is_a","term_name":"complete hydatidiform mole","termid":"MONDO:0016785"},{"relation_name":"is_a","term_name":"gestational trophoblastic neoplasm","termid":"MONDO:0018944"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydatidiform mole, recurrent, 2","secondary_identifiers":["GARD:18366","MEDGEN:481982","UMLS:C3280352","OMIM:614293"],"synonyms":[{"name":"HYDM2","type":"related"},{"name":"KHDC3L complete hydatidiform mole","type":"exact"},{"name":"complete hydatidiform mole caused by mutation in KHDC3L","type":"exact"},{"name":"hydatidiform MOLE, recurrent, 2","type":"related"},{"name":"hydatidiform Mole, complete","type":"related"},{"name":"hydatidiform Mole, recurrent, type 2","type":"exact"},{"name":"hydatidiform mole, recurrent, 2","type":"exact"}],"termid":"MONDO:0013671","xrefs":{"Monarch":{"xref_id":"0013671"}}}


id: GO:0015720
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amide transport","termid":"GO:0042886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"allantoin transport","synonyms":[{"name":"allantoin transmembrane transport","type":"exact"},{"name":"allantoin/allantoate transport","type":"broad"}],"termid":"GO:0015720"}


id: FYPO:0003235
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at centromere outer repeat regions is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H3-K9 methylation at centromere during vegetative growth","termid":"FYPO:0008070"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0001312","FYPO:0001320"],"is_obsolete":false,"name":"normal histone H3-K9 methylation at centromere outer repeat during vegetative growth","synonyms":[{"name":"normal histone H3 K9 methylation at centromere outer repeat during vegetative growth","type":"exact"},{"name":"normal histone H3-K9 methylation at centromere otr during vegetative growth","type":"exact"},{"name":"normal histone H3-K9 methylation at centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"normal histone H3-K9 methylation at centromeric outer repeat region during vegetative growth","type":"exact"},{"name":"normal histone H3-K9 methylation at pericentric region during vegetative growth","type":"related"},{"name":"normal histone H3-K9 methylation at pericentromeric region during vegetative growth","type":"related"},{"name":"normal histone H3K9me at centromere outer repeat during vegetative growth","type":"exact"},{"name":"normal histone lysine H3 K9 methylation at centromere outer repeat during vegetative growth","type":"exact"}],"termid":"FYPO:0003235"}


id: FYPO:0001076
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of a specific substance measured in a cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular physical quality phenotype","termid":"FYPO:0007723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal level of substance in cell","termid":"FYPO:0001076"}


id: PBO:0044665
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dicarbonyl and L-xylulose reductase","termid":"PBO:0044665"}


id: PBO:0083389
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps HRT1, a verified gene that encodes an SCF ubiquitin ligase subunit","termid":"PBO:0083389"}


id: PBO:0036347
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LEUcine requiring","termid":"PBO:0036347"}


id: SO:0000629
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An open reading frame found within the 5' UTR that can be translated and stall the translation of the downstream open reading frame.","definition_xrefs":["PMID:12890013"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA_region","termid":"SO:0000836"},{"relation_name":"part_of","term_name":"five_prime_UTR","termid":"SO:0000204"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"five_prime_open_reading_frame","synonyms":[{"name":"five prime open reading frame","type":"exact"}],"termid":"SO:0000629"}


id: FYPO:0005013
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased histone H4 acetylation during vegetative growth","termid":"FYPO:0005011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0002494","FYPO:0002274","FYPO:0001320"],"is_obsolete":false,"name":"decreased histone H4-K8 acetylation during vegetative growth","synonyms":[{"name":"decreased histone H4-K8 acetylation during mitotic cell cycle","type":"related"},{"name":"decreased histone H4K8 acetylation during vegetative growth","type":"exact"},{"name":"reduced histone H4-K8 acetylation during vegetative growth","type":"exact"}],"termid":"FYPO:0005013"}


id: GO:0009550
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis.","definition_xrefs":["PMID:15012255"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasmodesma","termid":"GO:0009506"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"primary plasmodesma","synonyms":[{"name":"simple plasmodesma","type":"exact"}],"termid":"GO:0009550"}


id: PBO:0031688
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_peroxisomal_transport","termid":"PBO:0031688"}


id: PBO:0069237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 492, pseudogene","termid":"PBO:0069237"}


id: FYPO:0003220
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at positions 9 and 14 of histone H3 is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete normal histone H3-K9K14 acetylation during vegetative growth (obsolete FYPO:0003220)","synonyms":[{"name":"normal histone H3 K9K14 acetylation during vegetative growth","type":"exact"},{"name":"normal histone H3-K9 and K14 acetylation during vegetative growth","type":"exact"},{"name":"normal histone H3-K9K14 acetylation during mitotic cell cycle","type":"related"},{"name":"normal histone lysine H3 K9K14 acetylation during vegetative growth","type":"exact"}],"termid":"FYPO:0003220"}


id: FYPO:0001285
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased phospholipid level","termid":"FYPO:0001289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased cellular phosphatidylethanolamine level","synonyms":[{"name":"decreased cellular PE level","type":"exact"},{"name":"decreased cellular phosphatidylethanolamine level during mitotic cell cycle","type":"related"},{"name":"decreased cellular phosphatidylethanolamine level during vegetative growth","type":"exact"},{"name":"decreased phosphatidylethanolamine accumulation","type":"related"},{"name":"reduced cellular phosphatidylethanolamine level","type":"exact"}],"termid":"FYPO:0001285"}


id: MONDO:0008041
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"early myoclonic encephalopathy","termid":"MONDO:0016022"},{"relation_name":"is_a","term_name":"myoclonic epilepsy","termid":"MONDO:0100577"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"myoclonic epilepsy, Hartung type","secondary_identifiers":["MEDGEN:371857","UMLS:C1834581","MESH:C563550","OMIM:159600"],"synonyms":[{"name":"myoclonic epilepsy, Hartung type","type":"exact"}],"termid":"MONDO:0008041","xrefs":{"Monarch":{"xref_id":"0008041"}}}


id: PBO:0078683
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Lys (TTT) 16-1","termid":"PBO:0078683"}


id: PBO:0012521
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-gene_product_of","termid":"PBO:0012521"}


id: PBO:0113167
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Integral ER membrane protein with type-III transmembrane domains; promotes ER membrane expansion by inhibiting the Nem1-Spo7 phosphatase complex, resulting in reduced dephosphorylation and activation of Pah1p; maintains homeostasis during ER stress; required for post-translational SRP-independent protein translocation into the ER; necessary for efficient targeting of the Trm1p to the inner nuclear membrane; mutations cause defects in cortical ER morphology; member of the SERINC superfamily","termid":"PBO:0113167"}


id: PBO:0060766
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B4 pseudogene 10","termid":"PBO:0060766"}


id: GO:0001594
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.","definition_xrefs":["GOC:mah","PMID:19325074"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled amine receptor activity","termid":"GO:0008227"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"trace-amine receptor activity","termid":"GO:0001594"}


id: MONDO:0001190
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An disease or disorder caused by infection with Brucella suis.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brucellosis","termid":"MONDO:0005683"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Brucella suis brucellosis","secondary_identifiers":["DOID:11076","UMLS:C0275594","MEDGEN:546685"],"synonyms":[{"name":"Brucella suis caused disease or disorder","type":"exact"},{"name":"Brucella suis disease or disorder","type":"exact"},{"name":"Brucella suis infectious disease","type":"exact"}],"termid":"MONDO:0001190","xrefs":{"Monarch":{"xref_id":"0001190"}}}


id: GO:0071854
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell wall macromolecule catabolic process involved in cell wall disassembly","termid":"GO:0070910"},{"relation_name":"part_of","term_name":"fungal-type cell wall disassembly","termid":"GO:0071853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0071554"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0071554","GO:0008150"],"is_obsolete":false,"name":"cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly","termid":"GO:0071854"}


id: PBO:0040017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"armadillo repeat containing 6","termid":"PBO:0040017"}


id: PBO:0116619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lncRNA senescence and mitophagy associated regulator of PRKN","termid":"PBO:0116619"}


id: MOD:01411
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-leucine residue to a monohydroxylated leucine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monohydroxylated residue","termid":"MOD:00425"},{"relation_name":"is_a","term_name":"hydroxylated leucine","termid":"MOD:01410"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monohydroxylated leucine","synonyms":[{"name":"Hy1Leu","type":"exact"}],"termid":"MOD:01411"}


id: GO:0047834
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.","definition_xrefs":["EC:1.1.1.122","MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"D-threo-aldose 1-dehydrogenase activity","secondary_identifiers":["RHEA:19645"],"synonyms":[{"name":"(2S,3R)-aldose dehydrogenase activity","type":"related"},{"name":"D-threo-aldose:NAD+ 1-oxidoreductase activity","type":"related"},{"name":"L-fucose (D-arabinose) dehydrogenase activity","type":"related"},{"name":"L-fucose dehydrogenase activity","type":"related"},{"name":"dehydrogenase, L-fucose","type":"related"}],"termid":"GO:0047834"}


id: PR:Q9USQ4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sim3 gene.","definition_xrefs":["UniProtKB:Q9USQ4","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NASP-related protein sim3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC577.15c","synonyms":[{"name":"CENP-A escort protein sim3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-sim3","type":"exact"},{"name":"silencing in the middle of the centromere protein 3 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9USQ4"}


id: GO:0018470
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 4-hydroxybutaraldehyde dehydrogenase activity (obsolete GO:0018470)","termid":"GO:0018470"}


id: GO:0030881
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to beta-2-microglobulin.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"beta-2-microglobulin binding","termid":"GO:0030881"}


id: PBO:0046218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin C pseudogene 11","termid":"PBO:0046218"}


id: PBO:0046512
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamate rich 6","termid":"PBO:0046512"}


id: GO:0016652
data:
  {"annotated_genes":["SJAG_01869"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[67793],"is_not":false,"summary":null,"term":"GO:0016652"}]},"cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.","definition_xrefs":["EC:1.6.1.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on NAD(P)H","termid":"GO:0016651"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01869":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"oxidoreductase activity, acting on NAD(P)H as acceptor","references_by_uniquename":{"GO_REF:0000002":null},"synonyms":[{"name":"oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor","type":"related"}],"termid":"GO:0016652","terms_by_termid":{"GO:0016652":null}}


id: PBO:0081740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNF670-ZNF695 readthrough (NMD candidate)","termid":"PBO:0081740"}


id: GO:0060787
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.","definition_xrefs":["GOC:sdb_2009","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fibroblast growth factor receptor signaling pathway","termid":"GO:0008543"},{"relation_name":"is_a","term_name":"regulation of embryonic development","termid":"GO:0045995"},{"relation_name":"is_a","term_name":"positive regulation of morphogenesis of an epithelium","termid":"GO:1905332"},{"relation_name":"is_a","term_name":"regulation of animal organ morphogenesis","termid":"GO:2000027"},{"relation_name":"positively_regulates","term_name":"posterior neural plate formation","termid":"GO:0090018"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway","synonyms":[{"name":"positive regulation of posterior neural plate formation by FGF receptor signaling pathway","type":"related"},{"name":"positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway","type":"exact"}],"termid":"GO:0060787"}


id: GO:0032691
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of interleukin-1 beta production","termid":"GO:0032651"},{"relation_name":"is_a","term_name":"negative regulation of interleukin-1 production","termid":"GO:0032692"},{"relation_name":"negatively_regulates","term_name":"interleukin-1 beta production","termid":"GO:0032611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of interleukin-1 beta production","secondary_identifiers":["GO:0050713","GO:0050724"],"synonyms":[{"name":"down regulation of interleukin-1 beta production","type":"exact"},{"name":"down-regulation of interleukin-1 beta production","type":"exact"},{"name":"downregulation of interleukin-1 beta production","type":"exact"},{"name":"inhibition of interleukin-1 beta production","type":"narrow"},{"name":"negative regulation of IL-1 beta production","type":"exact"},{"name":"negative regulation of interleukin-1 beta biosynthetic process","type":"narrow"},{"name":"negative regulation of interleukin-1 beta secretion","type":"narrow"}],"termid":"GO:0032691"}


id: PBO:0067769
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 69","termid":"PBO:0067769"}


id: PBO:0005741
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Extragenic Suppressor of Pim","termid":"PBO:0005741"}


id: PBO:0059406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein S33 pseudogene 3","termid":"PBO:0059406"}


id: MONDO:0858988
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autosomal recessive spastic paraplegia type 83 (obsolete MONDO:0858988)","termid":"MONDO:0858988","xrefs":{"Monarch":{"xref_id":"0858988"}}}


id: PBO:0031147
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_galactomannan_level","termid":"PBO:0031147"}


id: MONDO:0010167
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Encephalopathy due to urocanase deficiency is an extremely rare histidine metabolism disorder characterized by urocanic aciduria and other variable manifestations including intellectual deficit and intermittent ataxia in the 4 cases reported to date.","definition_xrefs":["Orphanet:210128"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of histidine metabolism","termid":"MONDO:0019228"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"urocanic aciduria","secondary_identifiers":["MESH:C536479","OMIM:276880","UMLS:C0268514","DOID:0112180","MEDGEN:120644","GARD:8539","HP:0012237","icd11.foundation:61773927","SCTID:60952007"],"synonyms":[{"name":"UROCD","type":"related"},{"name":"encephalopathy due to urocanase deficiency","type":"exact"},{"name":"urocanase deficiency","type":"related"},{"name":"urocanic aciduria","type":"exact"},{"name":"urocanic aciduria (disease)","type":"exact"}],"termid":"MONDO:0010167","xrefs":{"Monarch":{"xref_id":"0010167"}}}


id: PBO:0030386
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cell_cortex_morphology","termid":"PBO:0030386"}


id: PBO:0004242
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium-dependent serine/threonine protein phosphatase calcineurin, catalytic subunit Ppb1","termid":"PBO:0004242"}


id: _global:is_magnitude_of
data:
  {"annotation_feature_type":"gene","cv_name":"pato.ontology","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"is_magnitude_of","termid":"_global:is_magnitude_of"}


id: GO:0033924
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.","definition_xrefs":["EC:3.2.1.95"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824","GO:0016798"],"is_obsolete":false,"name":"dextran 1,6-alpha-isomaltotriosidase activity","secondary_identifiers":["MetaCyc:3.2.1.95-RXN"],"synonyms":[{"name":"1,6-alpha-D-glucan isomaltotriohydrolase activity","type":"related"},{"name":"exo-isomaltotriohydrolase activity","type":"related"}],"termid":"GO:0033924"}


id: MOD:01130
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass","definition_xrefs":["DeltaMass:297"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DeltaMass","termid":"MOD:00947"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SucPhencarb Lysyl","termid":"MOD:01130"}


id: GO:0005924
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. An adherens junction which connects a cell to the extracellular matrix.","definition_xrefs":["GOC:hb"],"gene_count":0,"genotype_count":0,"name":"obsolete cell-substrate adherens junction (obsolete GO:0005924)","synonyms":[{"name":"hemi-adherens junction","type":"related"}],"termid":"GO:0005924"}


id: PATO:0000987
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000987 relative consistency (obsolete PATO:0000987)","termid":"PATO:0000987"}


id: MONDO:0037938
data:
  {"annotated_genes":["SJAG_02388","SJAG_01061","SJAG_03556","SJAG_01070"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85406],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0100255"},{"annotations":[85218,85219],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009388"},{"annotations":[86684],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013404"}]},"cv_name":"mondo","definition":"An inherited metabolic disease that is has its basis in the disruption of aspartate family amino acid metabolic process.","definition_xrefs":["MONDO:patterns/inborn_metabolic"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of amino acid metabolism","termid":"MONDO:0004736"},{"relation_name":"is_a","term_name":"inborn disorder of amino acid and other organic acid metabolism","termid":"MONDO:0019189"},{"relation_name":"is_a","term_name":"disorder of organic acid metabolism","termid":"MONDO:0045022"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01061":null,"SJAG_01070":null,"SJAG_02388":null,"SJAG_03556":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"inborn disorder of aspartate family metabolism","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"inborn aspartate family amino acid metabolic process disorder","type":"exact"},{"name":"inborn error of aspartate family amino acid metabolic process","type":"exact"},{"name":"rare inborn error of aspartate family amino acid metabolic process","type":"exact"}],"termid":"MONDO:0037938","terms_by_termid":{"MONDO:0009388":null,"MONDO:0013404":null,"MONDO:0100255":null},"xrefs":{"Monarch":{"xref_id":"0037938"}}}


id: MONDO:0040870
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A form of polydipsia characterized by excessive fluid intake in the absence of physiological stimuli to drink.","definition_xrefs":["Wikipedia:Primary_polydipsia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"impulse control disorder","termid":"MONDO:0001162"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"primary polydipsia","termid":"MONDO:0040870","xrefs":{"Monarch":{"xref_id":"0040870"}}}


id: GO:0009543
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana.","definition_xrefs":["GOC:mtg_sensu","ISBN:0943088399"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plastid thylakoid lumen","termid":"GO:0031978"},{"relation_name":"part_of","term_name":"chloroplast thylakoid","termid":"GO:0009534"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737"],"is_obsolete":false,"name":"chloroplast thylakoid lumen","termid":"GO:0009543"}


id: GO:0034550
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O.","definition_xrefs":["UM-BBD_reactionID:r0838"],"gene_count":0,"genotype_count":0,"name":"obsolete dimethylarsinate reductase activity (obsolete GO:0034550)","termid":"GO:0034550"}


id: PBO:0052788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 27","termid":"PBO:0052788"}


id: FYPO:0003142
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methyl methanesulfonate is lower than normal. Total RNA or a specific RNA may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased RNA level during vegetative growth","termid":"FYPO:0001117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0006551","FYPO:0005447"],"is_obsolete":false,"name":"decreased RNA level during cellular response to methyl methanesulfonate","synonyms":[{"name":"decreased RNA accumulation during cellular response to methyl methanesulfonate","type":"related"},{"name":"decreased RNA level during cellular response to MMS","type":"exact"},{"name":"decreased RNA level during cellular response to methyl methanesulfonate during mitotic cell cycle","type":"related"},{"name":"decreased RNA level during cellular response to methyl methanesulfonate during vegetative growth","type":"exact"},{"name":"decreased RNA level during cellular response to methyl methanesulphonate","type":"exact"},{"name":"decreased mRNA level during cellular response to methyl methanesulfonate","type":"narrow"},{"name":"decreased transcript level during cellular response to methyl methanesulfonate","type":"exact"},{"name":"reduced RNA level during cellular response to methyl methanesulfonate","type":"exact"}],"termid":"FYPO:0003142"}


id: GO:0070967
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.","definition_xrefs":["GOC:dh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic acid binding","termid":"GO:0031406"},{"relation_name":"is_a","term_name":"carbohydrate derivative binding","termid":"GO:0097367"},{"relation_name":"is_a","term_name":"heterocyclic compound binding","termid":"GO:1901363"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"coenzyme F420 binding","termid":"GO:0070967"}


id: GO:0060329
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic actin-based contraction involved in cell motility","termid":"GO:0060327"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cytoplasmic actin-based contraction involved in rearward cell motility","synonyms":[{"name":"cytoplasmic actin-based contraction involved in rearward cell locomotion","type":"related"}],"termid":"GO:0060329"}


id: PBO:0045108
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dystrophin","termid":"PBO:0045108"}


id: PBO:0029286
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_localization_to_Mmi1_focus","termid":"PBO:0029286"}


id: MONDO:0020493
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Haddad syndrome is a rare congenital disorder in which congenital central hypoventilation syndrome (CCHS), or Ondine syndrome, occurs concurrently with Hirschsprung disease.","definition_xrefs":["Orphanet:99803"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal motility disease","termid":"MONDO:0021189"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"Haddad syndrome","secondary_identifiers":["MEDGEN:347052","GARD:16909","UMLS:C1859049","icd11.foundation:1685926536","SCTID:719972004","ICD10CM:G47.3"],"synonyms":[{"name":"Haddad syndrome","type":"exact"},{"name":"congenital central alveolar hypoventilation-Hirschsprung disease syndrome","type":"exact"},{"name":"ondine-Hirschsprung disease","type":"exact"},{"name":"ondine-Hirschsprung syndrome","type":"exact"}],"termid":"MONDO:0020493","xrefs":{"Monarch":{"xref_id":"0020493"}}}


id: PBO:0051645
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inosine monophosphate dehydrogenase 1","termid":"PBO:0051645"}


id: PBO:0045130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication helicase/nuclease 2","termid":"PBO:0045130"}


id: MONDO:0011297
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal dominant nocturnal frontal lobe epilepsy that has material basis in variation in the chromosome region 15q24.","definition_xrefs":["DOID:0060683","PMID:9758605"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sleep-related hypermotor epilepsy","termid":"MONDO:0000030"},{"relation_name":"is_a","term_name":"autosomal dominant nocturnal frontal lobe epilepsy","termid":"MONDO:0020300"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"autosomal dominant nocturnal frontal lobe epilepsy 2","secondary_identifiers":["OMIM:603204","MESH:C566400","UMLS:C1864125","GARD:15352","MEDGEN:351053"],"synonyms":[{"name":"ENFL2","type":"exact"},{"name":"autosomal dominant nocturnal frontal lobe epilepsy type 2","type":"exact"},{"name":"epilepsy, nocturnal frontal lobe, 2","type":"related"},{"name":"epilepsy, nocturnal frontal lobe, type 2","type":"exact"},{"name":"nocturnal frontal lobe epilepsy 2","type":"exact"}],"termid":"MONDO:0011297","xrefs":{"Monarch":{"xref_id":"0011297"}}}


id: PBO:0060749
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B2 pseudogene 2","termid":"PBO:0060749"}


id: GO:0140663
data:
  {"annotated_genes":["SJAG_02994","SJAG_02895"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[67431,67797],"is_not":false,"summary":null,"term":"GO:0140663"}]},"cv_name":"molecular_function","definition":"Binding to and delivering metal ions to a target protein, driven by ATP hydrolysis.","definition_xrefs":["PMID:16843540"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metallochaperone activity","termid":"GO:0016530"},{"relation_name":"is_a","term_name":"ATP-dependent activity","termid":"GO:0140657"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02895":null,"SJAG_02994":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140104"}],"interesting_parent_ids":["GO:0003674","GO:0140104"],"is_obsolete":false,"name":"ATP-dependent FeS chaperone activity","references_by_uniquename":{"GO_REF:0000002":null},"synonyms":[{"name":"ATP-dependent FeS carrier activity","type":"exact"}],"termid":"GO:0140663","terms_by_termid":{"GO:0140663":null}}


id: MONDO:0000163
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete breast-ovarian cancer, familial, susceptibility to (obsolete MONDO:0000163)","termid":"MONDO:0000163","xrefs":{"Monarch":{"xref_id":"0000163"}}}


id: PBO:0075276
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 19 pseudogene 1","termid":"PBO:0075276"}


id: PBO:0047157
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 185 member A","termid":"PBO:0047157"}


id: GO:0102839
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity (obsolete GO:0102839)","termid":"GO:0102839"}


id: GO:0014833
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool.","definition_xrefs":["PMID:16607119","GOC:ef","GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"somatic stem cell division","termid":"GO:0048103"},{"relation_name":"is_a","term_name":"asymmetric stem cell division","termid":"GO:0098722"},{"relation_name":"part_of","term_name":"skeletal muscle tissue development","termid":"GO:0007519"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"skeletal muscle satellite stem cell asymmetric division","synonyms":[{"name":"satellite cell asymmetric division","type":"exact"}],"termid":"GO:0014833"}


id: PBO:0059050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myeloid cell nuclear differentiation antigen","termid":"PBO:0059050"}


id: PBO:0072051
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S10 pseudogene 21","termid":"PBO:0072051"}


id: PBO:0042027
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 85B","termid":"PBO:0042027"}


id: SO:0000873
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transcript that is edited.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"guided_by","term_name":"guide_RNA","termid":"SO:0000602"},{"relation_name":"has_part","term_name":"anchor_binding_site","termid":"SO:0000977"},{"relation_name":"has_quality","term_name":"edited","termid":"SO:0000116"},{"relation_name":"is_a","term_name":"transcript","termid":"SO:0000673"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"edited_transcript","synonyms":[{"name":"edited transcript","type":"exact"}],"termid":"SO:0000873"}


id: PBO:0043016
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell adhesion molecule L1 like","termid":"PBO:0043016"}


id: GO:1990606
data:
  {"annotated_genes":["SJAG_02848","SJAG_02384"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[99724,102521],"is_not":false,"summary":null,"term":"GO:1990606"}]},"cv_name":"molecular_function","definition":"Generation of a 'twisting' activity resulting in the scission of a membrane, driven by GTP hydrolysis.","definition_xrefs":["PMID:11242086","PMID:24515348","PMID:23530241"],"direct_ancestors":[{"relation_name":"is_a","term_name":"GTPase motor activity","termid":"GO:0061791"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02384":null,"SJAG_02848":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003924"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003774"}],"interesting_parent_ids":["GO:0003774","GO:0016787","GO:0003924","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"membrane scission GTPase motor activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:1990606","terms_by_termid":{"GO:1990606":null}}


id: PBO:0076408
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TATA-box binding protein associated factor 5","termid":"PBO:0076408"}


id: PBO:0083863
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7","termid":"PBO:0083863"}


id: PBO:0073904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 15 member 2","termid":"PBO:0073904"}


id: PBO:0038272
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase allele types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amino_acid_deletion_and_mutation","termid":"PBO:0038272"}


id: PBO:0065894
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAB40A, member RAS oncogene family","termid":"PBO:0065894"}


id: PBO:0016559
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Meiotic Rna Binding protein","termid":"PBO:0016559"}


id: PBO:0001630
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase Rrp3 (predicted)","termid":"PBO:0001630"}


id: PBO:0001477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein Ssa1 (predicted)","termid":"PBO:0001477"}


id: GO:0051046
data:
  {"annotated_genes":["SJAG_03763","SJAG_00661","SJAG_04509","SJAG_02366"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[99936],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045921"},{"annotations":[98155,87663,93610],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017157"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of transport","termid":"GO:0051049"},{"relation_name":"regulates","term_name":"secretion","termid":"GO:0046903"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00661":null,"SJAG_02366":null,"SJAG_03763":null,"SJAG_04509":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of secretion","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0051046","terms_by_termid":{"GO:0017157":null,"GO:0045921":null}}


id: PBO:0060759
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B4 pseudogene 3","termid":"PBO:0060759"}


id: PBO:0110191
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial MIB complex subunit, human DNAJC11 ortholog Mib1","termid":"PBO:0110191"}


id: PBO:0029316
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_histone_H2A_phosphorylation_at_mating_type_locus","termid":"PBO:0029316"}


id: GO:0097072
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3.","definition_xrefs":["GOC:cna","PMID:12855817","PMID:14556004"],"direct_ancestors":[{"relation_name":"is_a","term_name":"interferon regulatory factor complex","termid":"GO:0097071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"interferon regulatory factor 3 complex","synonyms":[{"name":"IRF3:IRF3 complex","type":"exact"}],"termid":"GO:0097072"}


id: MONDO:0019847
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete congenital adrenal hypoplasia of maternal cause (obsolete MONDO:0019847)","secondary_identifiers":["Orphanet:95701"],"termid":"MONDO:0019847","xrefs":{"Monarch":{"xref_id":"0019847"}}}


id: MONDO:0009229
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"primary osteolysis","termid":"MONDO:0019707"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyaline fibromatosis syndrome","secondary_identifiers":["GARD:22029","UMLS:C5574677","DOID:0111669","Orphanet:498474","MEDGEN:1805033","OMIM:228600"],"synonyms":[{"name":"HFS","type":"related"},{"name":"hyaline fibromatosis syndrome","type":"exact"},{"name":"hyalinosis, systemic","type":"related"},{"name":"infantile systemic hyalinosis (former subtype)","type":"related"},{"name":"inherited systemic hyalinosis","type":"related"},{"name":"juvenile hyaline fibromatosis (former subtype)","type":"related"}],"termid":"MONDO:0009229","xrefs":{"Monarch":{"xref_id":"0009229"}}}


id: GO:0070456
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sugar-phosphatase activity","termid":"GO:0050308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003824","GO:0016788","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"galactose-1-phosphate phosphatase activity","termid":"GO:0070456"}


id: PBO:0070472
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L5 pseudogene 7","termid":"PBO:0070472"}


id: GO:0097730
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.","definition_xrefs":["GOC:kmv","PMID:20144998","GOC:cilia","GOC:dgh","PMID:17009929","PMID:22118931"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cilium","termid":"GO:0005929"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"non-motile cilium","secondary_identifiers":["GO:0031513"],"synonyms":[{"name":"immotile cilium","type":"exact"},{"name":"immotile primary cilium","type":"related"},{"name":"nonmotile cilium","type":"exact"},{"name":"nonmotile primary cilia","type":"related"},{"name":"nonmotile primary cilium","type":"related"},{"name":"sensory cilium","type":"related"}],"termid":"GO:0097730"}


id: GO:0043300
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of leukocyte degranulation.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immune effector process","termid":"GO:0002697"},{"relation_name":"is_a","term_name":"regulation of regulated secretory pathway","termid":"GO:1903305"},{"relation_name":"regulates","term_name":"leukocyte degranulation","termid":"GO:0043299"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0008150","GO:0016192","GO:0006810"],"is_obsolete":false,"name":"regulation of leukocyte degranulation","synonyms":[{"name":"regulation of immune cell degranulation","type":"exact"},{"name":"regulation of immune cell granule exocytosis","type":"exact"},{"name":"regulation of leucocyte degranulation","type":"exact"},{"name":"regulation of leukocyte granule exocytosis","type":"exact"}],"termid":"GO:0043300"}


id: PBO:0013806
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by H. sapiens TXNL1","termid":"PBO:0013806"}


id: PBO:0054973
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2387","termid":"PBO:0054973"}


id: PBO:0011156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase assembly protein Cox14 (predicted)","termid":"PBO:0011156"}


id: PBO:0046834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fatty acid binding protein 5 pseudogene 7","termid":"PBO:0046834"}


id: FYPO:0004940
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chloroacetaldehyde.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0002058","FYPO:0000257","FYPO:0000003","FYPO:0002060","FYPO:0000139"],"is_obsolete":false,"name":"normal growth on chloroacetaldehyde","synonyms":[{"name":"normal cell population growth in presence of chloroacetaldehyde","type":"exact"},{"name":"normal cell population growth on CAA","type":"exact"},{"name":"normal cell population growth on chloroacetaldehyde","type":"exact"},{"name":"normal cellular response to chloroacetaldehyde","type":"related"},{"name":"normal vegetative cell population growth on chloroacetaldehyde","type":"exact"}],"termid":"FYPO:0004940"}


id: MONDO:0021545
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign or malignant mesenchymal neoplasm arising from smooth, skeletal, or cardiac muscle.","definition_xrefs":["NCIT:C4063"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesenchymal cell neoplasm","termid":"MONDO:0002616"},{"relation_name":"is_a","term_name":"muscle tissue disorder","termid":"MONDO:0003939"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myomatous neoplasm","secondary_identifiers":["MESH:D009379","MESH:D019042","UMLS:C0282606","MEDGEN:76477"],"synonyms":[{"name":"muscle neoplasm","type":"exact"},{"name":"muscle tissue neoplasm","type":"related"},{"name":"muscle tissue neoplasms","type":"related"},{"name":"muscle tumor","type":"exact"},{"name":"muscle tumour","type":"exact"},{"name":"myoblastoma","type":"related"},{"name":"myoblastomas","type":"related"},{"name":"myofibroblastoma","type":"related"},{"name":"myofibroblastomas","type":"related"},{"name":"myomatous neoplasm","type":"exact"},{"name":"myomatous tumor","type":"exact"},{"name":"myomatous tumour","type":"exact"},{"name":"neoplasm of muscle","type":"exact"},{"name":"neoplasm of the muscle","type":"exact"},{"name":"neoplasm, muscle tissue","type":"related"},{"name":"tumor of muscle","type":"exact"},{"name":"tumor of the muscle","type":"exact"},{"name":"tumour of muscle","type":"exact"},{"name":"tumour of the muscle","type":"exact"}],"termid":"MONDO:0021545","xrefs":{"Monarch":{"xref_id":"0021545"}}}


id: PBO:0036213
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-ubiquitinated_protein_absent_from_cell_during_vegetative_growth","termid":"PBO:0036213"}


id: GO:1902147
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to cell cycle checkpoint signaling","termid":"GO:1902145"},{"relation_name":"regulates","term_name":"response to cytokinesis checkpoint signaling","termid":"GO:0072399"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of response to cytokinesis checkpoint signaling","secondary_identifiers":["GO:1902149"],"synonyms":[{"name":"regulation of cytokinesis checkpoint effector process","type":"exact"},{"name":"regulation of response to signal involved in cytokinesis checkpoint","type":"exact"}],"termid":"GO:1902147"}


id: GO:0034545
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.","definition_xrefs":["UM-BBD_reactionID:r0811"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances","termid":"GO:0016823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"fumarylpyruvate hydrolase activity","secondary_identifiers":["EC:3.7.1.20","RHEA:26168"],"termid":"GO:0034545"}


id: GO:0034525
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-naphthaldehyde dehydrogenase activity (obsolete GO:0034525)","termid":"GO:0034525"}


id: GO:0042245
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in the repair of damaged RNA.","definition_xrefs":["PMID:11000254","PMID:11070075","UniProtKB-KW:KW-0692"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA metabolic process","termid":"GO:0016070"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"RNA repair","termid":"GO:0042245"}


id: MONDO:0012111
data:
  {"annotated_genes":["SJAG_00228"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86226],"is_not":false,"summary":null,"term":"MONDO:0012111"}]},"cv_name":"mondo","definition":"Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the MYL3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00228":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"hypertrophic cardiomyopathy 8","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:C563866","MEDGEN:324806","UMLS:C1837471","OMIM:608751","DOID:0110314"],"synonyms":[{"name":"CMH8","type":"related"},{"name":"MYL3 hypertrophic cardiomyopathy","type":"exact"},{"name":"cardiomyopathy hypertrophic mid-left ventricular chamber type 1","type":"exact"},{"name":"cardiomyopathy, familial hypertrophic, 8","type":"exact"},{"name":"cardiomyopathy, familial hypertrophic, type 8","type":"exact"},{"name":"cardiomyopathy, hypertrophic, 8","type":"exact"},{"name":"cardiomyopathy, hypertrophic, mid-left ventricular chamber type, 1","type":"related"},{"name":"hypertrophic cardiomyopathy 8","type":"exact"},{"name":"hypertrophic cardiomyopathy caused by mutation in MYL3","type":"exact"},{"name":"hypertrophic cardiomyopathy type 8","type":"exact"}],"termid":"MONDO:0012111","terms_by_termid":{"MONDO:0012111":null},"xrefs":{"Monarch":{"xref_id":"0012111"}}}


id: GO:0044324
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transcription that contributes to the specification of the anterior/posterior axis.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transcription involved in anterior/posterior axis specification (obsolete GO:0044324)","termid":"GO:0044324"}


id: PBO:0057527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 644a","termid":"PBO:0057527"}


id: MONDO:0011975
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies due to 14q32.2 maternally expressed gene defect","termid":"MONDO:0016779"},{"relation_name":"is_a","term_name":"chromosome 14 disorder","termid":"MONDO:0700021"},{"relation_name":"is_a","term_name":"uniparental disomy","termid":"MONDO:0700086"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paternal uniparental disomy of chromosome 14","secondary_identifiers":["UMLS:C5680251","OMIM:608149","icd11.foundation:1835121942","Orphanet:96334","GARD:5409","MESH:C536471","NANDO:1200685","MEDGEN:1843450"],"synonyms":[{"name":"KAGAMI-Ogata syndrome","type":"related"},{"name":"UPD(14)pat","type":"exact"},{"name":"paternal uniparental disomy 14","type":"related"},{"name":"paternal uniparental disomy of chromosome 14","type":"exact"},{"name":"paternal uniparental disomy of chromosome type 14","type":"exact"},{"name":"uniparental disomy, paternal, chromosome 14","type":"related"}],"termid":"MONDO:0011975","xrefs":{"Monarch":{"xref_id":"0011975"}}}


id: GO:0043230
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.","definition_xrefs":["GOC:jl","PMID:9914479"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle","termid":"GO:0043226"},{"relation_name":"part_of","term_name":"extracellular region","termid":"GO:0005576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005576"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005576","GO:0005575"],"is_obsolete":false,"name":"extracellular organelle","termid":"GO:0043230"}


id: GO:0018333
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine.","definition_xrefs":["RESID:AA0038"],"gene_count":0,"genotype_count":0,"name":"obsolete enzyme active site formation via O-phospho-L-threonine (obsolete GO:0018333)","termid":"GO:0018333"}


id: GO:0018273
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of peptidyl-lysine to form N6-retinal-L-lysine.","definition_xrefs":["RESID:AA0120"],"gene_count":0,"genotype_count":0,"name":"obsolete protein-chromophore linkage via peptidyl-N6-retinal-L-lysine (obsolete GO:0018273)","termid":"GO:0018273"}


id: MONDO:0001870
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute post streptococcal glomerulonephritis is an immunologic response of the kidney to infection, characterized by the sudden appearance of edema, hematuria, proteinuria and hypertension. It is essentially a disease of childhood that accounts for approximately 90% of renal disorders in children. The disease occurs especially in children between the ages of 2 and 12 years and young adults, and more often in male than in female.","direct_ancestors":[{"relation_name":"is_a","term_name":"glomerulonephritis","termid":"MONDO:0002462"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"acute poststreptococcal glomerulonephritis","secondary_identifiers":["MEDGEN:140785","NCIT:C35443","UMLS:C0403414","DOID:14064","SCTID:68544003"],"synonyms":[{"name":"post-streptococcal glomerulonephritis","type":"related"}],"termid":"MONDO:0001870","xrefs":{"Monarch":{"xref_id":"0001870"}}}


id: GO:0044250
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.","definition_xrefs":["GOC:jl","Wikipedia:Hibernation"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of metabolic process","termid":"GO:0009892"},{"relation_name":"part_of","term_name":"hibernation","termid":"GO:0042750"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of metabolic activity involved in hibernation","synonyms":[{"name":"down regulation of metabolic activity during hibernation","type":"related"},{"name":"down-regulation of metabolic activity during hibernation","type":"related"},{"name":"downregulation of metabolic activity during hibernation","type":"related"},{"name":"inhibition of metabolic activity during hibernation","type":"narrow"},{"name":"negative regulation of metabolic activity during hibernation","type":"related"}],"termid":"GO:0044250"}


id: MONDO:0017519
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"symbrachydactyly of hands and feet","termid":"MONDO:0015516"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"symbrachydactyly of hand and foot, unilateral","secondary_identifiers":["Orphanet:295136"],"termid":"MONDO:0017519","xrefs":{"Monarch":{"xref_id":"0017519"}}}


id: PBO:0055900
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 23","termid":"PBO:0055900"}


id: MONDO:0008274
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fibrous dysplasia affecting more than one bone. When it is associated with café-au-lait skin pigmentation and endocrine disorders, it is known as McCune-Albright syndrome.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fibrous dysplasia","termid":"MONDO:0000845"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polyostotic fibrous dysplasia","secondary_identifiers":["UMLS:C0016065","GARD:4213","NCIT:C34610","ICD10CM:Q78.1","icd11.foundation:771587091","ICD9:756.54","MESH:D005359","Orphanet:93276","MedDRA:10036120","MEDGEN:5180","SCTID:36517007"],"synonyms":[{"name":"PFD","type":"exact"},{"name":"fibrous dysplasia of bone","type":"broad"},{"name":"polyostotic fibrous dysplasia of bone","type":"exact"}],"termid":"MONDO:0008274","xrefs":{"Monarch":{"xref_id":"0008274"}}}


id: GO:0038168
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. An epidermal growth factor receptor signaling pathway in which the signal transmitted via I-kappaB-kinase (IKK)-dependent activation of the transcription factor NF-kappaB.","definition_xrefs":["GOC:bf","PMID:22132240"],"gene_count":0,"genotype_count":0,"name":"obsolete epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade (obsolete GO:0038168)","synonyms":[{"name":"EGFR signaling pathway via IKK-dependent activation of NF-kappaB","type":"exact"},{"name":"EGFR signaling pathway via IKK/NF-kappaB cascade","type":"exact"}],"termid":"GO:0038168"}


id: MONDO:0021187
data:
  {"annotated_genes":["SJAG_01072","SJAG_02432","SJAG_04785"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86277,86276,86278],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011369"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic disease","termid":"MONDO:0005066"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01072":null,"SJAG_02432":null,"SJAG_04785":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"hyperlipidemia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["HP:0003077","ICD9:272.4","MEDGEN:5692","MESH:D006949","UMLS:C0020473","ICD10CM:E78.5","SCTID:55822004"],"synonyms":[{"name":"hyperlipemia","type":"related"},{"name":"hyperlipemias","type":"related"},{"name":"hyperlipidemia","type":"exact"},{"name":"hyperlipidemia (disease)","type":"exact"},{"name":"lipemia","type":"related"},{"name":"lipemias","type":"related"},{"name":"lipidemia","type":"related"},{"name":"lipidemias","type":"related"}],"termid":"MONDO:0021187","terms_by_termid":{"MONDO:0011369":null},"xrefs":{"Monarch":{"xref_id":"0021187"}}}


id: MONDO:0010943
data:
  {"annotated_genes":["SJAG_01903"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87056],"is_not":false,"summary":null,"term":"MONDO:0010943"}]},"cv_name":"mondo","definition":"A schizophrenia that has material basis in an autosomal dominant mutation of PRODH on chromosome 22q11.21.","definition_xrefs":["DOID:0070080"],"direct_ancestors":[{"relation_name":"is_a","term_name":"schizophrenia, susceptibility to","termid":"MONDO:0100182"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01903":null},"genotype_count":0,"is_obsolete":false,"name":"schizophrenia 4","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1833247","MEDGEN:371517","OMIM:600850"],"synonyms":[{"name":"SCZD4","type":"exact"},{"name":"schizophrenia 4","type":"exact"},{"name":"schizophrenia susceptibility locus, chromosome 22Q11-related","type":"related"},{"name":"schizophrenia type 4","type":"exact"},{"name":"schizophrenia, susceptibility to, 4","type":"exact"}],"termid":"MONDO:0010943","terms_by_termid":{"MONDO:0010943":null},"xrefs":{"Monarch":{"xref_id":"0010943"}}}


id: GO:0047433
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H+ = 2-methylbutanal + CO2.","definition_xrefs":["EC:4.1.1.72","RHEA:21108"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"branched-chain-2-oxoacid decarboxylase activity","secondary_identifiers":["KEGG_REACTION:R03894","MetaCyc:4.1.1.72-RXN"],"synonyms":[{"name":"(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)","type":"related"},{"name":"(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity","type":"related"},{"name":"BCKA","type":"related"},{"name":"branched-chain alpha-keto acid decarboxylase activity","type":"related"},{"name":"branched-chain keto acid decarboxylase activity","type":"related"},{"name":"branched-chain oxo acid decarboxylase activity","type":"related"}],"termid":"GO:0047433"}


id: GO:0004728
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.","definition_xrefs":["EC:3.1.3.48"],"gene_count":0,"genotype_count":0,"name":"obsolete signal transducer, downstream of receptor, with protein tyrosine phosphatase activity (obsolete GO:0004728)","synonyms":[{"name":"receptor signaling protein tyrosine phosphatase activity","type":"exact"},{"name":"receptor signalling protein tyrosine phosphatase activity","type":"exact"}],"termid":"GO:0004728"}


id: PBO:0051112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 1-68 (pseudogene)","termid":"PBO:0051112"}


id: GO:0045747
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of Notch signaling pathway","termid":"GO:0008593"},{"relation_name":"is_a","term_name":"positive regulation of signal transduction","termid":"GO:0009967"},{"relation_name":"positively_regulates","term_name":"Notch signaling pathway","termid":"GO:0007219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of Notch signaling pathway","synonyms":[{"name":"activation of Notch signaling pathway","type":"narrow"},{"name":"positive regulation of N signaling pathway","type":"exact"},{"name":"positive regulation of N signalling pathway","type":"exact"},{"name":"positive regulation of Notch signalling pathway","type":"exact"},{"name":"stimulation of Notch signaling pathway","type":"narrow"},{"name":"up regulation of Notch signaling pathway","type":"exact"},{"name":"up-regulation of Notch signaling pathway","type":"exact"},{"name":"upregulation of Notch signaling pathway","type":"exact"}],"termid":"GO:0045747"}


id: PBO:0057992
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3916","termid":"PBO:0057992"}


id: PBO:0091084
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DSB-forming protein Rec12/Spo11","termid":"PBO:0091084"}


id: PBO:0039806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP ribosylation factor 2, pseudogene","termid":"PBO:0039806"}


id: MONDO:0007503
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"microtia","termid":"MONDO:0010920"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ear without helix","secondary_identifiers":["UMLS:C1851899","MEDGEN:343678","OMIM:128800"],"synonyms":[{"name":"ear without helix","type":"exact"}],"termid":"MONDO:0007503","xrefs":{"Monarch":{"xref_id":"0007503"}}}


id: MONDO:0003847
data:
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