# terms

id: PBO:0085379
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Plasma membrane ATP binding cassette (ABC) transporter; multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element; PDR15 has a paralog, PDR5, that arose from the whole genome duplication","termid":"PBO:0085379"}


id: PBO:0003895
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongator complex subunit Iki1 (predicted)","termid":"PBO:0003895"}


id: PBO:0004959
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidase family C26 protein","termid":"PBO:0004959"}


id: PATO:0001639
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A necessity quality inhering in a process by virtue of the bearer's being non-essential or dispensable.","definition_xrefs":["PATO:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"necessity of occurrent","termid":"PATO:0001637"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unnecessary (occurrent)","termid":"PATO:0001639"}


id: PBO:0028269
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_nitric_oxide_level_during_cellular_response_to_cadmium_ion","termid":"PBO:0028269"}


id: PBO:0082052
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian and C. elegans apoptotic nucleases","termid":"PBO:0082052"}


id: GO:0030760
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.","definition_xrefs":["RHEA:16893","EC:2.1.1.87"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0016741","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"pyridine N-methyltransferase activity","secondary_identifiers":["Reactome:R-HSA-175987","KEGG_REACTION:R02862","MetaCyc:PYRIDINE-N-METHYLTRANSFERASE-RXN"],"synonyms":[{"name":"S-adenosyl-L-methionine:pyridine N-methyltransferase activity","type":"related"},{"name":"pyridine methyltransferase activity","type":"related"}],"termid":"GO:0030760"}


id: PBO:0074182
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 38 member 4","termid":"PBO:0074182"}


id: GO:0018813
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).","definition_xrefs":["UM-BBD_enzymeID:r0338"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity","secondary_identifiers":["EC:4.1.2.45","RHEA:27389"],"termid":"GO:0018813"}


id: PBO:0048082
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ferritin light chain pseudogene 3","termid":"PBO:0048082"}


id: FYPO:0001208
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in a cell is too low to detect.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell during vegetative growth","termid":"FYPO:0001329"},{"relation_name":"is_a","term_name":"substance absent from cell","termid":"FYPO:0001888"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"substance absent from cell during vegetative growth","synonyms":[{"name":"substance absent from cell during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001208"}


id: GO:0035882
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.","definition_xrefs":["PMID:9066270","PMID:8158250","PMID:7479775","GOC:bf","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ultradian rhythm","termid":"GO:0007624"},{"relation_name":"part_of","term_name":"defecation","termid":"GO:0030421"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"defecation rhythm","synonyms":[{"name":"DMP","type":"exact"},{"name":"defecation behavior","type":"related"},{"name":"defecation cycle","type":"exact"},{"name":"defecation motor program","type":"exact"}],"termid":"GO:0035882"}


id: PBO:0057299
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 513c","termid":"PBO:0057299"}


id: MONDO:0020253
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete syndrome with a symptomatic strabismus (obsolete MONDO:0020253)","secondary_identifiers":["Orphanet:98683"],"termid":"MONDO:0020253","xrefs":{"Monarch":{"xref_id":"0020253"}}}


id: MONDO:0011206
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ventriculomegaly with defects of the radius and kidney","secondary_identifiers":["UMLS:C1865780","MEDGEN:400843","MESH:C566565","OMIM:602200"],"synonyms":[{"name":"ventriculomegaly with defects of the radius and kidney","type":"exact"}],"termid":"MONDO:0011206","xrefs":{"Monarch":{"xref_id":"0011206"}}}


id: GO:0048496
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"part_of","term_name":"animal organ development","termid":"GO:0048513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"maintenance of animal organ identity","termid":"GO:0048496"}


id: PATO:0000129
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000129 absolute weight (obsolete PATO:0000129)","termid":"PATO:0000129"}


id: PATO:0000259
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000259 visual_ability (obsolete PATO:0000259)","termid":"PATO:0000259"}


id: PR:Q9UT86
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An anaphase-promoting complex subunit 11 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaphase-promoting complex subunit 11 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC343.03","secondary_identifiers":["UniProtKB:Q9UT86"],"synonyms":[{"name":"20S cyclosome/APC complex protein apc11 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPAC343.03","type":"related"},{"name":"Spom972h-ANAPC11","type":"exact"}],"termid":"PR:Q9UT86"}


id: GO:2000135
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of secondary heart field cardioblast proliferation.","definition_xrefs":["GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of regulation of secondary heart field cardioblast proliferation (obsolete GO:2000135)","synonyms":[{"name":"positive regulation of regulation of second heart field cardioblast proliferation","type":"exact"},{"name":"positive regulation of regulation of secondary heart field cardioblast proliferation","type":"exact"}],"termid":"GO:2000135"}


id: MOD:00259
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively crosslinks an L-tyrosine residue and the 5'-end of DNA through a phosphodiester bond to form O4'-(phospho-5'-DNA)-L-tyrosine.","definition_xrefs":["PubMed:1861973","PubMed:2940511","RESID:AA0254","PubMed:3684578"],"direct_ancestors":[{"relation_name":"is_a","term_name":"deoxyribonucleic acid linked residue","termid":"MOD:00750"},{"relation_name":"is_a","term_name":"modified L-tyrosine residue","termid":"MOD:00919"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O4'-(phospho-5'-DNA)-L-tyrosine","synonyms":[{"name":"(S)-2-amino-3-[4-(5'-deoxyribonucleic acid phosphonoxy)phenyl]propanoic acid","type":"exact"},{"name":"ACT_SITE O-(5'-phospho-DNA)-tyrosine intermediate","type":"exact"},{"name":"MOD_RES O-(5'-phospho-DNA)-tyrosine","type":"exact"},{"name":"O4'-(phospho-5'-DNA)-L-tyrosine","type":"exact"},{"name":"O4'-L-tyrosine 5'-DNA phosphodiester","type":"exact"}],"termid":"MOD:00259"}


id: PR:Q10487
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mfs1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10487"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transporter mfs1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17C9.16c","synonyms":[{"name":"Spom972h-mfs1","type":"exact"}],"termid":"PR:Q10487"}


id: PBO:0002422
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleoside reductase large subunit Cdc22","termid":"PBO:0002422"}


id: PBO:0057581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 885","termid":"PBO:0057581"}


id: GO:1902871
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","GOC:mr","PMID:16872597"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of neuron differentiation","termid":"GO:0045666"},{"relation_name":"is_a","term_name":"regulation of amacrine cell differentiation","termid":"GO:1902869"},{"relation_name":"positively_regulates","term_name":"amacrine cell differentiation","termid":"GO:0035881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of amacrine cell differentiation","synonyms":[{"name":"activation of amacrine cell differentiation","type":"narrow"},{"name":"activation of amacrine neuron differentiation","type":"narrow"},{"name":"positive regulation of amacrine neuron differentiation","type":"exact"},{"name":"up regulation of amacrine cell differentiation","type":"exact"},{"name":"up regulation of amacrine neuron differentiation","type":"exact"},{"name":"up-regulation of amacrine cell differentiation","type":"exact"},{"name":"up-regulation of amacrine neuron differentiation","type":"exact"},{"name":"upregulation of amacrine cell differentiation","type":"exact"},{"name":"upregulation of amacrine neuron differentiation","type":"exact"}],"termid":"GO:1902871"}


id: PR:Q9UTJ2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A phosphomannomutase 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO01572"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphomannomutase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1556.07","secondary_identifiers":["UniProtKB:Q9UTJ2"],"synonyms":[{"name":"PMM (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-PMM1","type":"exact"}],"termid":"PR:Q9UTJ2"}


id: GO:0140632
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex.","definition_xrefs":["PMID:33420028","PMID:33542150","PMID:33420033"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"},{"relation_name":"part_of","term_name":"inflammasome-mediated signaling pathway","termid":"GO:0141084"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0065003","GO:0044085","GO:0023052"],"is_obsolete":false,"name":"canonical inflammasome complex assembly","termid":"GO:0140632"}


id: FYECO:0000263
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in medium containing glucose (typically <2% w/v), salts, water and with L-glutamatic acid as the nitrogen source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping defined medium","termid":"FYECO:0000013"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucose MM, glutamate nitrogen source","synonyms":[{"name":"EMMG","type":"related"},{"name":"PMG","type":"narrow"},{"name":"glucose minimal medium, glutamate nitrogen source","type":"exact"},{"name":"standard glucose minimal medium, glutamate nitrogen source","type":"related"}],"termid":"FYECO:0000263"}


id: GO:0071682
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The volume enclosed by the membrane of an endocytic vesicle.","definition_xrefs":["GOC:pde"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular organelle lumen","termid":"GO:0070013"},{"relation_name":"part_of","term_name":"endocytic vesicle","termid":"GO:0030139"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0031410","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"endocytic vesicle lumen","termid":"GO:0071682"}


id: PBO:0017770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NMS complex subunit Nuf2","termid":"PBO:0017770"}


id: PBO:0056123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LYSET pseudogene 1","termid":"PBO:0056123"}


id: GO:0019593
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexitol biosynthetic process","termid":"GO:0019406"},{"relation_name":"is_a","term_name":"mannitol metabolic process","termid":"GO:0019594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"mannitol biosynthetic process","secondary_identifiers":["MetaCyc:PWY-3881"],"synonyms":[{"name":"mannitol anabolism","type":"exact"},{"name":"mannitol biosynthesis","type":"exact"},{"name":"mannitol formation","type":"exact"},{"name":"mannitol synthesis","type":"exact"}],"termid":"GO:0019593"}


id: GO:0061772
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a xenobiotic through the blood-nerve barrier.","definition_xrefs":["GOC:dph","PMID:22733753"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xenobiotic transport","termid":"GO:0042908"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"xenobiotic transport across blood-nerve barrier","synonyms":[{"name":"drug transport across blood-nerve barrier","type":"related"},{"name":"drug transport across perineurial barrier","type":"exact"}],"termid":"GO:0061772"}


id: GO:2000121
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of removal of superoxide radicals.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of superoxide metabolic process","termid":"GO:0090322"},{"relation_name":"is_a","term_name":"regulation of cellular response to oxidative stress","termid":"GO:1900407"},{"relation_name":"is_a","term_name":"regulation of response to reactive oxygen species","termid":"GO:1901031"},{"relation_name":"regulates","term_name":"removal of superoxide radicals","termid":"GO:0019430"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0098754"}],"interesting_parent_ids":["GO:0008150","GO:0098754"],"is_obsolete":false,"name":"regulation of removal of superoxide radicals","synonyms":[{"name":"regulation of removal of O2-","type":"exact"},{"name":"regulation of removal of oxygen free radicals","type":"exact"}],"termid":"GO:2000121"}


id: PBO:0076248
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SUV39H2 divergent transcript","termid":"PBO:0076248"}


id: GO:0036071
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains.","definition_xrefs":["GOC:sart","PMID:19948734"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fucosylation","termid":"GO:0036065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"N-glycan fucosylation","synonyms":[{"name":"glycoprotein fucosylation","type":"related"}],"termid":"GO:0036071"}


id: MONDO:0014389
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic, glycogen storage disorder characterized by polyglucosan accumulation in various tissues, manifesting with progressive proximal muscle weakness in the lower limbs and rapidly progressive, usually dilated, cardiomyopathy. Hepatic involvement and growth retardation may be associated. Early-onset immunodeficiency and autoinflammation, presenting with recurrent bacterial infections, have also been reported.","definition_xrefs":["Orphanet:397937"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete neuromuscular disease with dilated cardiomyopathy (obsolete MONDO:0016334)","termid":"MONDO:0016334"},{"relation_name":"excluded_subClassOf","term_name":"obsolete neurometabolic disease (obsolete MONDO:0019058)","termid":"MONDO:0019058"},{"relation_name":"is_a","term_name":"polyglucosan body myopathy","termid":"MONDO:0000192"},{"relation_name":"is_a","term_name":"disorder of glycogen metabolism","termid":"MONDO:0002412"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0005066","MONDO:0005336"],"is_obsolete":false,"name":"polyglucosan body myopathy 1 with or without immunodeficiency","secondary_identifiers":["UMLS:C4014605","OMIM:615895","MEDGEN:863042","GARD:17643","NANDO:2200766"],"synonyms":[{"name":"PGBM1","type":"exact"},{"name":"polyglucosan body myopathy 1 with or without immunodeficiency","type":"exact"},{"name":"polyglucosan body myopathy type 1","type":"exact"},{"name":"polyglucosan body myopathy, early-onset, with or without immunodeficiency","type":"exact"}],"termid":"MONDO:0014389","xrefs":{"Monarch":{"xref_id":"0014389"}}}


id: PBO:0085505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; nascent Rps3p is bound by specific chaperone Yar1p during translation; homologous to mammalian ribosomal protein S3 and bacterial S3","termid":"PBO:0085505"}


id: GO:0035622
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).","definition_xrefs":["PMID:20614624","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"common bile duct development","termid":"GO:0061009"},{"relation_name":"part_of","term_name":"liver development","termid":"GO:0001889"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"intrahepatic bile duct development","synonyms":[{"name":"IHBD development","type":"exact"},{"name":"intrahepatic biliary duct development","type":"exact"}],"termid":"GO:0035622"}


id: PBO:0108909
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KIAA1191 pseudogene 3","termid":"PBO:0108909"}


id: PBO:0052984
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L antigen family member 3","termid":"PBO:0052984"}


id: GO:0044859
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a protein is incorporated into a plasma membrane raft.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to plasma membrane raft","termid":"GO:0044860"},{"relation_name":"is_a","term_name":"protein insertion into membrane raft","termid":"GO:0071210"},{"relation_name":"is_a","term_name":"protein insertion into plasma membrane","termid":"GO:0098737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0051179","GO:0061024","GO:0008150"],"is_obsolete":false,"name":"protein insertion into plasma membrane raft","termid":"GO:0044859"}


id: PBO:0082956
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p","termid":"PBO:0082956"}


id: PBO:0064434
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PNP pseudogene 1","termid":"PBO:0064434"}


id: PBO:0076131
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SUB1 pseudogene 2","termid":"PBO:0076131"}


id: GO:0044653
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.","definition_xrefs":["PMID:18556189"],"gene_count":0,"genotype_count":0,"name":"obsolete dextrin alpha-glucosidase activity (obsolete GO:0044653)","termid":"GO:0044653"}


id: PBO:0000941
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.3.3.1","termid":"PBO:0000941"}


id: PBO:0071916
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S3 pseudogene 1","termid":"PBO:0071916"}


id: PBO:0109301
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"codon-optimization increases the mRNA concentration","termid":"PBO:0109301"}


id: MONDO:0000935
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign exophytic neoplasm that arises from the larynx, usually the true vocal cords. It is related to human papillomavirus infection and may arise as a single or multiple lesions. It is characterized by the presence of a connective tissue core covered by stratified squamous epithelium. Hoarseness is the presenting symptom. Transformation to carcinoma is rare.","definition_xrefs":["NCIT:C7742"],"direct_ancestors":[{"relation_name":"is_a","term_name":"squamous papilloma","termid":"MONDO:0001825"},{"relation_name":"is_a","term_name":"benign laryngeal neoplasm","termid":"MONDO:0002354"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"larynx squamous papilloma","secondary_identifiers":["UMLS:C0240164","DOID:10071","MEDGEN:116099"],"synonyms":[{"name":"laryngeal papilloma","type":"exact"},{"name":"larynx papilloma","type":"exact"},{"name":"larynx squamous papilloma","type":"exact"},{"name":"papilloma of larynx","type":"exact"},{"name":"papilloma of the larynx","type":"exact"},{"name":"squamous papilloma of larynx","type":"exact"},{"name":"squamous papilloma of the larynx","type":"exact"}],"termid":"MONDO:0000935","xrefs":{"Monarch":{"xref_id":"0000935"}}}


id: PBO:0060387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"marginal zone B and B1 cell specific protein","termid":"PBO:0060387"}


id: PBO:0069222
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 477, pseudogene","termid":"PBO:0069222"}


id: PBO:0078441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor gamma constant 1","termid":"PBO:0078441"}


id: PBO:0083401
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps ORF YER134C","termid":"PBO:0083401"}


id: MONDO:0006653
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fibrosis of the lung parenchyma caused by inhalation of carbon and silica dust. It manifests as shortness of breath.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pneumoconiosis","termid":"MONDO:0015926"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anthracosilicosis","secondary_identifiers":["UMLS:C0003164","SCTID:33548005","DOID:10324","EFO:1000813","CSP:2596-4484","MESH:D000874","MedDRA:10050363","NCIT:C34389","MEDGEN:1958"],"termid":"MONDO:0006653","xrefs":{"Monarch":{"xref_id":"0006653"}}}


id: GO:0022032
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.","definition_xrefs":["GO_REF:0000021","GOC:cls","GOC:dph","GOC:dgh","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"telencephalon glial cell migration","termid":"GO:0022030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"telencephalon oligodendrocyte cell migration","termid":"GO:0022032"}


id: PBO:0079079
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-iMet (anticodon CAT) 1-7","termid":"PBO:0079079"}


id: PBO:0080551
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WBP1L pseudogene 10","termid":"PBO:0080551"}


id: GO:1903126
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.","definition_xrefs":["PMID:24554434","GOC:als","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell cycle process","termid":"GO:0010948"},{"relation_name":"is_a","term_name":"regulation of centriole-centriole cohesion","termid":"GO:0030997"},{"relation_name":"negatively_regulates","term_name":"centriole-centriole cohesion","termid":"GO:0010457"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0000226"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0007010"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049","GO:0000226","GO:0007010"],"is_obsolete":false,"name":"negative regulation of centriole-centriole cohesion","synonyms":[{"name":"down regulation of centriole-centriole cohesion","type":"exact"},{"name":"down-regulation of centriole-centriole cohesion","type":"exact"},{"name":"downregulation of centriole-centriole cohesion","type":"exact"},{"name":"inhibition of centriole-centriole cohesion","type":"narrow"}],"termid":"GO:1903126"}


id: GO:0036080
data:
  {"annotated_genes":["SJAG_00339","SJAG_01960"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[93110],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005457"},{"annotations":[71548],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005458"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.","definition_xrefs":["PMID:19948734","GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide-sugar transmembrane transporter activity","termid":"GO:0005338"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00339":null,"SJAG_01960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"purine nucleotide-sugar transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0036080","terms_by_termid":{"GO:0005457":null,"GO:0005458":null}}


id: PBO:0000116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-coding RNA,poly(A)-bearing (predicted)","termid":"PBO:0000116"}


id: PBO:0086040
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function involved in DNA repair","termid":"PBO:0086040"}


id: GO:0000354
data:
  {"annotated_genes":["SJAG_04230"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117572],"is_not":false,"summary":null,"term":"GO:0000354"}]},"cv_name":"biological_process","definition":"Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.","definition_xrefs":["ISBN:0879695897","GOC:krc","GOC:mtg_mpo"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-RNA complex assembly","termid":"GO:0022618"},{"relation_name":"part_of","term_name":"spliceosomal complex assembly","termid":"GO:0000245"},{"relation_name":"part_of","term_name":"mRNA cis splicing, via spliceosome","termid":"GO:0045292"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04230":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0016071"},{"rel_name":"part_of","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0010467","GO:0016071","GO:0008150","GO:0065003"],"is_obsolete":false,"name":"cis assembly of pre-catalytic spliceosome","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0000361","GO:0000360"],"synonyms":[{"name":"cis assembly of U12-type pre-catalytic spliceosome","type":"narrow"},{"name":"cis assembly of U2-type pre-catalytic spliceosome","type":"narrow"},{"name":"formation of spliceosomal A2-1 complex","type":"narrow"},{"name":"formation of spliceosomal B1 complex","type":"narrow"},{"name":"spliceosomal A2-1 complex biosynthesis","type":"narrow"},{"name":"spliceosomal A2-1 complex formation","type":"narrow"},{"name":"spliceosomal B1 complex biosynthesis","type":"narrow"},{"name":"spliceosomal B1 complex formation","type":"narrow"}],"termid":"GO:0000354","terms_by_termid":{"GO:0000354":null}}


id: MONDO:0020779
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any dysfunction in the growth of cartilage.","definition_xrefs":["NCIT:C34466"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal system disorder","termid":"MONDO:0005172"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cartilage development disorder","secondary_identifiers":["MEDGEN:935","UMLS:C0008449","ICD9:756.4","SCTID:67988000","ICD9:756.9"],"synonyms":[{"name":"Congenital anomaly of cartilage","type":"related"},{"name":"abnormal development of cartilage","type":"related"},{"name":"cartilage development disorder","type":"exact"},{"name":"chondrodystrophy","type":"exact"}],"termid":"MONDO:0020779","xrefs":{"Monarch":{"xref_id":"0020779"}}}


id: PBO:0090392
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CCR4-Not complex ubiquitin-protein ligase E3 subunit 4","termid":"PBO:0090392"}


id: PBO:0043661
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coenzyme Q6, monooxygenase","termid":"PBO:0043661"}


id: MONDO:0022414
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete allain-babin-demarquez syndrome (obsolete MONDO:0022414)","secondary_identifiers":["Orphanet:1526"],"synonyms":[{"name":"acro cephalo synostosis","type":"related"},{"name":"craniosynostosis synostoses hypertensive nephropathy","type":"related"}],"termid":"MONDO:0022414","xrefs":{"Monarch":{"xref_id":"0022414"}}}


id: GO:0052929
data:
  {"annotated_genes":["SJAG_01704","SJAG_02288"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70095,74704],"is_not":false,"summary":null,"term":"GO:0052929"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate.","definition_xrefs":["PMID:31936900","PMID:33095240","RHEA:60012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenylyltransferase activity","termid":"GO:0070566"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a tRNA","termid":"GO:0140101"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01704":null,"SJAG_02288":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0016779"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0140101","GO:0016779","GO:0140098","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R09386"],"synonyms":[{"name":"ATP:3'-CC-tRNA adenylyltransferase activity","type":"exact"},{"name":"ATP:tRNA adenylyltransferase activity","type":"broad"}],"termid":"GO:0052929","terms_by_termid":{"GO:0052929":null}}


id: FYPO:0005803
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane of the lateral part of the cell occurs more slowly than normal.","definition_xrefs":["PMID:25837586","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein movement within plasma membrane during vegetative growth","termid":"FYPO:0005800"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased rate of protein movement within plasma membrane at cell side","synonyms":[{"name":"decreased rate of protein movement within plasma membrane at cell side during mitotic cell cycle","type":"related"},{"name":"decreased rate of protein movement within plasma membrane at cell side during vegetative growth","type":"exact"},{"name":"decreased rate of protein movement within plasma membrane at lateral part of cell","type":"exact"},{"name":"reduced rate of protein movement within plasma membrane at cell side","type":"exact"},{"name":"slow protein movement within plasma membrane at cell side","type":"exact"}],"termid":"FYPO:0005803"}


id: GO:0008388
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid hydroxylase activity","termid":"GO:0008395"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","termid":"GO:0016705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"testosterone 15-alpha-hydroxylase activity","synonyms":[{"name":"cytochrome P450 CYP2A4","type":"narrow"}],"termid":"GO:0008388"}


id: PBO:0072727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ryanodine receptor 2","termid":"PBO:0072727"}


id: PBO:0079798
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP glucuronosyltransferase family 2 member B7","termid":"PBO:0079798"}


id: CHEBI:17202
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IMP","termid":"CHEBI:17202"}


id: PBO:0080611
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 45 pseudogene 1","termid":"PBO:0080611"}


id: GO:0099177
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of trans-synaptic signaling.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell communication","termid":"GO:0010646"},{"relation_name":"is_a","term_name":"regulation of signaling","termid":"GO:0023051"},{"relation_name":"regulates","term_name":"trans-synaptic signaling","termid":"GO:0099537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of trans-synaptic signaling","termid":"GO:0099177"}


id: FYPO:0003128
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested in M phase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"abnormal cell cycle arrest in mitotic M phase","termid":"FYPO:0000608"},{"relation_name":"is_a","term_name":"abnormal cell cycle arrest in mitotic M phase","termid":"FYPO:0000608"},{"relation_name":"is_a","term_name":"inviable elongated mononucleate aseptate cell","termid":"FYPO:0000839"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000032","FYPO:0000004","FYPO:0000631","FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0000005"],"is_obsolete":false,"name":"inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase","synonyms":[{"name":"elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest in M phase during vegetative growth","type":"exact"},{"name":"elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell arrested in M","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in M phase during mitotic cell cycle","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitosis","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic M phase arrest","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest in M phase","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic nuclear division arrest","type":"exact"},{"name":"lethal; elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic M phase","type":"exact"},{"name":"mitotic M-phase arrested elongated inviable mononucleate aseptate vegetative cell","type":"exact"},{"name":"mitotic cell cycle arrest in M-phase with elongated inviable mononucleate aseptate cell","type":"exact"},{"name":"nuclear division arrest without septation (elongated cell)","type":"exact"}],"termid":"FYPO:0003128"}


id: PATO:0000454
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A pilosity quality inhering in a bearer by virtue of the bearer's being covered with hair or hairlike projections.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pilosity","termid":"PATO:0000066"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hairy","termid":"PATO:0000454"}


id: PBO:0049094
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 151","termid":"PBO:0049094"}


id: PBO:0073304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SERPINE1 mRNA binding protein 1","termid":"PBO:0073304"}


id: MONDO:0018673
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Idiopathic hypertrophic pachymeningitis (IHP) is a rare disorder causing inflammation and thickening of the outer layer (dura) of the brain and/or spinal cord. IHP can be widespread or cause tumor-like lesions. Before IHP can be diagnosed, other conditions including sarcoidosis, tumors, meningioma, infections (syphilis, tuberculosis, and Lyme disease), and autoimmune diseases (rheumatoid arthritis, Sjogrenbs syndrome, Wegenerbs granulomatosis, and IgG4-related disease) must be ruled out. IHP often presents with headache and cranial nerve impairment. Treatment may involve prednisone and/or an immune suppressing drug. This treatment often improves symptoms, however complete recovery is rare. Surgery may be recommended for people with advanced or severe IHP. Some people with IHP have no symptoms and may not need treatment.","definition_xrefs":["GARD:0013256"],"direct_ancestors":[{"relation_name":"is_a","term_name":"IgG4-related disease","termid":"MONDO:0017287"},{"relation_name":"is_a","term_name":"inflammatory disease","termid":"MONDO:0021166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"IgG4-related pachymeningitis","secondary_identifiers":["Orphanet:449427","GARD:13256","SCTID:762282007","MEDGEN:1627405","icd11.foundation:1140264879","UMLS:C4545992"],"synonyms":[{"name":"idiopathic hypertrophic cranial pachymeningitis","type":"related"},{"name":"idiopathic hypertrophic craniospinal pachymeningitis","type":"related"},{"name":"idiopathic hypertrophic pachymeningitis","type":"exact"},{"name":"idiopathic hypertrophic spinal pachymeningitis","type":"related"}],"termid":"MONDO:0018673","xrefs":{"Monarch":{"xref_id":"0018673"}}}


id: PR:000028947
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A thioredoxin reduced form in Schizosaccharomyces pombe. The reduced Cys are Cys-30 and Cys-33 in UniProtKB:O14463.","definition_xrefs":["PRO:CNA","PMID:22245228"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein","termid":"PR:000000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trx1/Red+","pombase_gene_id":"SPAC7D4.07c","synonyms":[{"name":"PomBase_original_PRO_term_name: thioredoxin-1 reduced form (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-TXN/Red+","type":"exact"},{"name":"trx1/Red+","type":"exact"}],"termid":"PR:000028947"}


id: FYPO:0002693
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002682"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000003","FYPO:0000139","FYPO:0005447","FYPO:0002682"],"is_obsolete":false,"name":"resistance to diamide","synonyms":[{"name":"resistance to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide","type":"exact"},{"name":"resistance to diamide during mitotic cell cycle","type":"related"},{"name":"resistance to diamide during vegetative growth","type":"exact"},{"name":"resistant to diamide","type":"exact"}],"termid":"FYPO:0002693"}


id: GO:0047620
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.","definition_xrefs":["MetaCyc:ACYLGLYCEROL-KINASE-RXN","EC:2.7.1.94"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0016301","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"acylglycerol kinase activity","secondary_identifiers":["Reactome:R-HSA-5696074","RHEA:19293"],"synonyms":[{"name":"ATP:acylglycerol 3-phosphotransferase activity","type":"related"},{"name":"MGK","type":"related"},{"name":"monoacylglycerol kinase (phosphorylating)","type":"related"},{"name":"monoacylglycerol kinase activity","type":"related"},{"name":"monoglyceride kinase activity","type":"related"},{"name":"monoglyceride phosphokinase activity","type":"related"},{"name":"sn-2-monoacylglycerol kinase activity","type":"related"}],"termid":"GO:0047620"}


id: MONDO:0008163
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic developmental defect during embryogenesis characterized by distinct facial features (long triangular face, broad forehead, narrow nose and mandible, high arched palate), prominent, dysmorphic ears (low-set and cup-shaped with large conchae and hypoplastic tragus, antitragus and lobe), long neck, preauricular and/or branchial fistulas and/or cysts, hypoplastic cervical muscles with sloping shoulders and clavicles, winged, low, and laterally-set scapulae, hearing impairment and mild intellectual deficit. Vertebral defects and short stature may also be associated.","definition_xrefs":["Orphanet:2792"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mandibulofacial dysostosis","termid":"MONDO:0015483"},{"relation_name":"is_a","term_name":"hereditary otorhinolaryngologic disease","termid":"MONDO:0018751"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"otofaciocervical syndrome","secondary_identifiers":["MEDGEN:322257","OMIMPS:166780","UMLS:C1833691","GARD:4169","MESH:C563481","MESH:C537074"],"synonyms":[{"name":"Fara Chlupackova syndrome","type":"exact"},{"name":"Fara-Chlupackova syndrome","type":"exact"},{"name":"OFC syndrome","type":"exact"},{"name":"familial oto-facio-cervical dysmorphia","type":"related"}],"termid":"MONDO:0008163","xrefs":{"Monarch":{"xref_id":"0008163"}}}


id: MONDO:1012229
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"progressive spinal myelopathy, non-human animal","termid":"MONDO:1011858"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progressive spinal myelopathy, cattle","secondary_identifiers":["OMIA:000832-9913"],"termid":"MONDO:1012229","xrefs":{"Monarch":{"xref_id":"1012229"}}}


id: GO:0098610
data:
  {"annotated_genes":["SJAG_04723","SJAG_04720","SJAG_01253","SJAG_00239","SJAG_04191","SJAG_00926","SJAG_03473","SJAG_01975","SJAG_00910","SJAG_03802","SJAG_03484","SJAG_02380"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[69750,76340,78256,76800],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000128"},{"annotations":[103306],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036349"},{"annotations":[103307,106011],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0060257"},{"annotations":[113827,108512,115885,108389,111122,105659],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1900735"}]},"cv_name":"biological_process","definition":"The attachment of two unicellular organisms to each other.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell adhesion","termid":"GO:0098609"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00239":null,"SJAG_00910":null,"SJAG_00926":null,"SJAG_01253":null,"SJAG_01975":null,"SJAG_02380":null,"SJAG_03473":null,"SJAG_03484":null,"SJAG_03802":null,"SJAG_04191":null,"SJAG_04720":null,"SJAG_04723":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"adhesion between unicellular organisms","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0098741"],"synonyms":[{"name":"adhesion between unicellular organisms via cell-wall interaction","type":"narrow"},{"name":"multi-organismal cell-cell adhesion","type":"broad"}],"termid":"GO:0098610","terms_by_termid":{"GO:0000128":null,"GO:0036349":null,"GO:0060257":null,"GO:1900735":null}}


id: FYPO:0000445
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G1 phase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle arrest in mitotic interphase","termid":"FYPO:0000837"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000631"],"is_obsolete":false,"name":"cell cycle arrest in mitotic G1 phase","synonyms":[{"name":"cell cycle arrest in G1 phase during mitotic cell cycle","type":"exact"},{"name":"cell cycle arrest in mitotic G1 phase during vegetative growth","type":"exact"},{"name":"mitotic G1 phase arrest","type":"exact"},{"name":"mitotic cell cycle arrest in G1 phase","type":"exact"},{"name":"mitotic cell cycle progression in G1 phase: arrested","type":"related"}],"termid":"FYPO:0000445"}


id: PATO:0001763
data:
  {"annotation_feature_type":"gene","cv_name":"quality","direct_ancestors":[{"relation_name":"is_a","term_name":"female fertility","termid":"PATO:0000277"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"female semi-sterile","termid":"PATO:0001763"}


id: PBO:0053308
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LIN28B antisense RNA 1","termid":"PBO:0053308"}


id: MONDO:1010927
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital pseudomyotonia that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital pseudomyotonia, non-human animal","termid":"MONDO:1010201"},{"relation_name":"is_a","term_name":"myopathy, dog","termid":"MONDO:1010917"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital pseudomyotonia, dog","secondary_identifiers":["OMIA:001464-9615"],"termid":"MONDO:1010927","xrefs":{"Monarch":{"xref_id":"1010927"}}}


id: MONDO:0041656
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A very serious type of heart attack during which one of the heart’s major arteries (one of the arteries that supplies oxygen and nutrient-rich blood to the heart muscle) is blocked. ST-segment elevation is an abnormality detected on the 12-lead ECG.","direct_ancestors":[{"relation_name":"is_a","term_name":"acute myocardial infarction","termid":"MONDO:0004781"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"ST-elevation myocardial infarction","secondary_identifiers":["SCTID:401303003","MESH:D000072657"],"synonyms":[{"name":"ST segment elevation myocardial infarction","type":"exact"},{"name":"STEMI","type":"exact"},{"name":"acute-ST segment elevation myocardial infarction","type":"exact"}],"termid":"MONDO:0041656","xrefs":{"Monarch":{"xref_id":"0041656"}}}


id: MONDO:0015932
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A non-syndromic urogenital tract malformation that involves the female organism.","definition_xrefs":["MONDO:design_pattern"],"gene_count":0,"genotype_count":0,"name":"obsolete non-syndromic urogenital tract malformation of female (obsolete MONDO:0015932)","secondary_identifiers":["Orphanet:182117"],"synonyms":[{"name":"female organism non-syndromic urogenital tract malformation","type":"exact"},{"name":"isolated urogenital tract malformation of female","type":"related"},{"name":"non-syndromic urogenital tract malformation of female organism","type":"exact"},{"name":"nonsyndromic urogenital tract malformation of female","type":"exact"}],"termid":"MONDO:0015932","xrefs":{"Monarch":{"xref_id":"0015932"}}}


id: PBO:0072163
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S15a pseudogene 40","termid":"PBO:0072163"}


id: MONDO:0043075
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"renal tubular acidosis","termid":"MONDO:0001909"},{"relation_name":"is_a","term_name":"neuroaxonal dystrophy","termid":"MONDO:0002283"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005559","MONDO:0005240"],"is_obsolete":false,"name":"neuroaxonal dystrophy renal tubular acidosis","secondary_identifiers":["MEDGEN:419816","MESH:C537386","GARD:349","UMLS:C2931479"],"synonyms":[{"name":"CNS disorder characterised by severe behavioural retardation, hypotonia, inability to talk, marked tremors, gait disturbances and inability to concentr","type":"related"},{"name":"CNS disorder characterized by severe behavioral retardation, hypotonia, inability to talk, marked tremors, gait disturbances and inability to concentr","type":"related"},{"name":"Maccario Mena weir syndrome","type":"related"}],"termid":"MONDO:0043075","xrefs":{"Monarch":{"xref_id":"0043075"}}}


id: PBO:0043720
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 6B2","termid":"PBO:0043720"}


id: PBO:0091745
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPBC18H10.16 was previously designated as can1","termid":"PBO:0091745"}


id: PBO:0068047
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 352","termid":"PBO:0068047"}


id: MONDO:0004568
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An ileus caused by abdominal or pelvic surgery, infections, disorders that affect the muscles and nerves, and medications. Signs and symptoms include those of intestinal obstruction.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ileus","termid":"MONDO:0004567"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"paralytic ileus","secondary_identifiers":["SCTID:55525008","NCIT:C93045","DOID:8442","HP:0002590","icd11.foundation:1868011045","MESH:D007418","ICD9:560.1","MEDGEN:18293","UMLS:C0030446"],"synonyms":[{"name":"paralytic ileus","type":"exact"},{"name":"paralytic ileus (disease)","type":"exact"}],"termid":"MONDO:0004568","xrefs":{"Monarch":{"xref_id":"0004568"}}}


id: GO:0051068
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.","definition_xrefs":["ISBN:0721601464"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sulfur compound metabolic process","termid":"GO:0006790"},{"relation_name":"is_a","term_name":"amide metabolic process","termid":"GO:0043603"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006790","GO:0008150"],"is_obsolete":false,"name":"dihydrolipoamide metabolic process","synonyms":[{"name":"dihydrolipoamide metabolism","type":"exact"},{"name":"dihydrolipoamide reduction","type":"narrow"},{"name":"dihydrothioctamide metabolic process","type":"exact"},{"name":"dihydrothioctamide metabolism","type":"exact"}],"termid":"GO:0051068"}


id: GO:0098006
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.","definition_xrefs":["GOC:bm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral DNA genome packaging","termid":"GO:0019073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"viral DNA genome packaging, headful","synonyms":[{"name":"phage headful packaging","type":"narrow"}],"termid":"GO:0098006"}


id: PATO:0001083
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001083 acceleration value (obsolete PATO:0001083)","termid":"PATO:0001083"}


id: PBO:0091439
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prospore membrane copper transmembrane transporter Mfc1","termid":"PBO:0091439"}


id: PBO:0077481
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 201","termid":"PBO:0077481"}


id: GO:0045009
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.","definition_xrefs":["ISBN:0198506732","PMID:8970154"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic vesicle","termid":"GO:0031410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0031410","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"chitosome","termid":"GO:0045009"}


id: GO:0060204
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic vesicle lumen","termid":"GO:0060205"},{"relation_name":"part_of","term_name":"clathrin-sculpted glutamate transport vesicle","termid":"GO:0060199"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0031410"],"is_obsolete":false,"name":"clathrin-sculpted glutamate transport vesicle lumen","synonyms":[{"name":"clathrin sculpted glutamate constitutive secretory pathway transport vesicle lumen","type":"exact"},{"name":"clathrin sculpted glutamate transport vesicle lumen","type":"exact"}],"termid":"GO:0060204"}


id: GO:0015666
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA endonuclease activity","termid":"GO:0004520"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140097"}],"interesting_parent_ids":["GO:0140097","GO:0016788","GO:0003674","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"restriction endodeoxyribonuclease activity","synonyms":[{"name":"restriction endonuclease activity","type":"exact"},{"name":"restriction enzyme activity","type":"exact"}],"termid":"GO:0015666"}


id: GO:0033804
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine, and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.","definition_xrefs":["EC:2.1.1.156"],"gene_count":0,"genotype_count":0,"name":"obsolete glycine/sarcosine N-methyltransferase activity (obsolete GO:0033804)","synonyms":[{"name":"ApGSMT","type":"related"},{"name":"GMT","type":"related"},{"name":"GSMT","type":"related"},{"name":"S-adenosyl-L-methionine:sarcosine N-methyltransferase activity","type":"related"},{"name":"glycine sarcosine N-methyltransferase activity","type":"related"},{"name":"glycine-sarcosine methyltransferase activity","type":"related"},{"name":"glycine/sarcosine N-methyltransferase activity","type":"exact"}],"termid":"GO:0033804"}


id: GO:0043830
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.","definition_xrefs":["PMID:2509466"],"gene_count":0,"genotype_count":0,"name":"obsolete thiol-driven fumarate reductase activity (obsolete GO:0043830)","termid":"GO:0043830"}


id: GO:0075100
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by host of symbiont protein kinase-mediated signal transduction (obsolete GO:0075100)","termid":"GO:0075100"}


id: MONDO:0002769
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Whitish or yellowish mucosal vaginal discharge.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vaginal discharge","termid":"MONDO:0002770"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukorrhea","secondary_identifiers":["MESH:D007973","DOID:3766","MEDGEN:44134","UMLS:C0023533"],"synonyms":[{"name":"discharge - leukorrhea","type":"exact"},{"name":"leukorrhea of vagina","type":"exact"}],"termid":"MONDO:0002769","xrefs":{"Monarch":{"xref_id":"0002769"}}}


id: MONDO:0028226
data:
  {"annotated_genes":["SJAG_03889"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[84808],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014118"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"severe congenital neutropenia","termid":"MONDO:0018542"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03889":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0006025","MONDO:0005046"],"is_obsolete":false,"name":"autosomal recessive severe congenital neutropenia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C176624","UMLS:C5447331","GARD:21834","MEDGEN:1781858","Orphanet:439849"],"termid":"MONDO:0028226","terms_by_termid":{"MONDO:0014118":null},"xrefs":{"Monarch":{"xref_id":"0028226"}}}


id: PBO:0062897
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-oxoacid CoA-transferase 2 pseudogene 1","termid":"PBO:0062897"}


id: GO:1900551
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secondary metabolite biosynthetic process","termid":"GO:0044550"},{"relation_name":"is_a","term_name":"N',N'',N'''-triacetylfusarinine C metabolic process","termid":"GO:1900549"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"N',N'',N'''-triacetylfusarinine C biosynthetic process","synonyms":[{"name":"N',N'',N'''-triacetylfusarinine C anabolism","type":"exact"},{"name":"N',N'',N'''-triacetylfusarinine C biosynthesis","type":"exact"},{"name":"N',N'',N'''-triacetylfusarinine C formation","type":"exact"},{"name":"N',N'',N'''-triacetylfusarinine C synthesis","type":"exact"}],"termid":"GO:1900551"}


id: PBO:0110869
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone deacetylase (class II), SHREC complex Clr3","termid":"PBO:0110869"}


id: GO:0062203
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D.","definition_xrefs":["RHEA:62180","PMID:29315936"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-oxygen lyase activity, acting on phosphates","termid":"GO:0016838"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"Viteagnusin D synthase activity","termid":"GO:0062203"}


id: MONDO:0017219
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Microform holoprosencephaly is a benign form of holoprosencephaly (HPE) characterized by midline defects without the typical HPE defect in brain cleavage.","definition_xrefs":["Orphanet:280200"],"direct_ancestors":[{"relation_name":"is_a","term_name":"holoprosencephaly","termid":"MONDO:0016296"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"microform holoprosencephaly","secondary_identifiers":["DOID:0111380","ICD10CM:Q04.2","icd11.foundation:44293173","GARD:17290","MEDGEN:1711978","UMLS:C5393309"],"synonyms":[{"name":"HPE, minor form","type":"exact"},{"name":"HPE-L","type":"exact"},{"name":"HoloprosencC)phalie, minor form","type":"exact"},{"name":"Holoprosencéphalie, minor form","type":"exact"},{"name":"Microform HPE","type":"exact"},{"name":"holoprosencephaly-like","type":"exact"}],"termid":"MONDO:0017219","xrefs":{"Monarch":{"xref_id":"0017219"}}}


id: FYPO:0002926
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which an interaction between a protein and polyadenylated RNA (poly(A)RNA) does not occur. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein-RNA interaction","termid":"FYPO:0002133"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0002131"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0000652","FYPO:0002131","FYPO:0001985"],"is_obsolete":false,"name":"abolished poly(A) RNA binding","synonyms":[{"name":"abolished adenosine recognition in polyA tail","type":"narrow"},{"name":"abolished polyA RNA binding","type":"exact"},{"name":"abolished polyadenylated RNA binding","type":"exact"},{"name":"abolished protein-poly(A) RNA interaction","type":"exact"},{"name":"poly(A) RNA binding abolished","type":"exact"}],"termid":"FYPO:0002926"}


id: PBO:0030920
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_vegetative_phenotype","termid":"PBO:0030920"}


id: PBO:0068004
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 306","termid":"PBO:0068004"}


id: PBO:0071819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S2 pseudogene 14","termid":"PBO:0071819"}


id: MONDO:0009585
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited neurodegenerative disorder","termid":"MONDO:0024237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"encephalopathy due to beta-mercaptolactate-cysteine disulfiduria","secondary_identifiers":["MEDGEN:208661","Orphanet:1035","GARD:654","MESH:C563085","OMIM:249650","UMLS:C0796055"],"synonyms":[{"name":"3-mercaptopyruvate sulfurtransferase deficiency","type":"exact"},{"name":"Ampola syndrome","type":"exact"},{"name":"Beta-mercaptolactate cysteine disulfiduria","type":"related"},{"name":"MCDU","type":"related"},{"name":"disulfiduria, mixed","type":"related"},{"name":"mercaptolactate-cysteine disulfiduria","type":"related"}],"termid":"MONDO:0009585","xrefs":{"Monarch":{"xref_id":"0009585"}}}


id: GO:0030978
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  {"annotated_genes":["SJAG_04184","SJAG_02916","SJAG_03057","SJAG_04236","SJAG_00424","SJAG_04666","SJAG_02278","SJAG_01028","SJAG_00610"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73030,70325,73168,71274,78464],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070600"},{"annotations":[89199,102599,92190,94698],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0070610"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucan metabolic process","termid":"GO:0044042"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00424":null,"SJAG_00610":null,"SJAG_01028":null,"SJAG_02278":null,"SJAG_02916":null,"SJAG_03057":null,"SJAG_04184":null,"SJAG_04236":null,"SJAG_04666":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"alpha-glucan metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"alpha-glucan metabolism","type":"exact"}],"termid":"GO:0030978","terms_by_termid":{"GO:0070600":null,"GO:0070610":null}}


id: PBO:0086028
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; YET3 null mutant decreases the level of secreted invertase; homolog of human BAP31 protein; protein abundance increases in response to DNA replication stress","termid":"PBO:0086028"}


id: GO:0018601
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4-nitrophenol + H+ + NADH + O2 = 4-nitrocatechol + H2O + NAD+.","definition_xrefs":["EC:1.14.13.29","RHEA:12568"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"4-nitrophenol 2-monooxygenase activity","secondary_identifiers":["MetaCyc:4-NITROPHENOL-2-MONOOXYGENASE-RXN","UM-BBD_reactionID:r0230","KEGG_REACTION:R03023"],"synonyms":[{"name":"4-nitrophenol hydroxylase activity","type":"related"},{"name":"4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)","type":"related"},{"name":"4-nitrophenol-2-hydroxylase activity","type":"related"}],"termid":"GO:0018601"}


id: MONDO:1011051
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Polycystic kidney disease that occurs in springbok.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polycystic kidney disease, non-human animal","termid":"MONDO:1010262"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polycystic kidney disease, springbok","secondary_identifiers":["OMIA:000807-59523"],"termid":"MONDO:1011051","xrefs":{"Monarch":{"xref_id":"1011051"}}}


id: GO:1901784
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving p-cresol.","definition_xrefs":["PMID:10623531","GOC:yaf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cresol metabolic process","termid":"GO:0042212"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"p-cresol metabolic process","synonyms":[{"name":"p-cresol metabolism","type":"exact"}],"termid":"GO:1901784"}


id: SO:0002035
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  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A primary transcript encoding a lncRNA.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nc_primary_transcript","termid":"SO:0000483"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lncRNA_primary_transcript","synonyms":[{"name":"lncRNA primary transcript","type":"exact"}],"termid":"SO:0002035"}


id: MONDO:0005420
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  {"annotated_genes":["SJAG_01926","SJAG_02463","SJAG_01941"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85691],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0026731"},{"annotations":[85461,85462],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010134"}]},"cv_name":"mondo","definition":"Abnormally low levels of thyroid hormone.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thyroid gland disorder","termid":"MONDO:0003240"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01926":null,"SJAG_01941":null,"SJAG_02463":null},"genotype_count":0,"is_obsolete":false,"name":"hypothyroidism","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C26800","ICD9:244.9","DOID:1459","NANDO:2100120","UMLS:C0020676","MEDGEN:6991","SCTID:40930008","MESH:D007037","EFO:0004705","icd11.foundation:1722092627"],"synonyms":[{"name":"hypothyroid","type":"related"},{"name":"hypothyroidism","type":"exact"},{"name":"thyroid deficiency","type":"exact"},{"name":"thyroid insufficiency","type":"exact"},{"name":"underactive thyroid","type":"exact"}],"termid":"MONDO:0005420","terms_by_termid":{"MONDO:0010134":null,"MONDO:0026731":null},"xrefs":{"Monarch":{"xref_id":"0005420"}}}


id: PBO:0111802
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  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"abhydrolase family","termid":"PBO:0111802"}


id: GO:0046486
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id: GO:1905817
data:
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id: GO:0033551
data:
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id: PBO:0011069
data:
  {"annotation_feature_type":"gene","cv_name":"species_dist","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved in metazoa","termid":"PBO:0011069"}


id: PBO:0078775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Asn (anticodon GTT) 2-7","termid":"PBO:0078775"}


id: PBO:0039308
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alkB homolog 3, alpha-ketoglutarate dependent dioxygenase","termid":"PBO:0039308"}


id: PBO:0088246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor TFIIIA","termid":"PBO:0088246"}


id: FYPO:0006384
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of endocytosis is decreased when the cell is subject to nitrogen starvation. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal endocytosis","termid":"FYPO:0003886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000138","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"decreased rate of endocytosis during nitrogen starvation","synonyms":[{"name":"decreased rate of actin-mediated endocytosis during nitrogen starvation","type":"exact"},{"name":"decreased rate of endocytosis during nitrogen depletion","type":"exact"},{"name":"decreased rate of endocytosis during nitrogen deprivation","type":"exact"},{"name":"decreased rate of protein internalization during nitrogen starvation","type":"narrow"},{"name":"reduced rate of endocytosis during nitrogen starvation","type":"exact"}],"termid":"FYPO:0006384"}


id: GO:1902442
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.","definition_xrefs":["GOC:TermGenie","PMID:21052097","GOC:dph","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein-containing complex assembly","termid":"GO:0043254"},{"relation_name":"regulates","term_name":"ripoptosome assembly involved in necroptotic process","termid":"GO:1901026"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"regulation of ripoptosome assembly involved in necroptotic process","synonyms":[{"name":"regulation of ripoptosome assembly involved in necroptosis","type":"narrow"}],"termid":"GO:1902442"}


id: GO:0075186
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"regulation of infection cushion formation","termid":"GO:0075184"},{"relation_name":"negatively_regulates","term_name":"infection cushion formation","termid":"GO:0075183"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of infection cushion formation","synonyms":[{"name":"negative regulation of infection cushion formation on or near host","type":"exact"}],"termid":"GO:0075186"}


id: PBO:0005659
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MutS protein homolog","termid":"PBO:0005659"}


id: PBO:0067859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 161","termid":"PBO:0067859"}


id: PR:Q9P6R8
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cwf24 gene.","definition_xrefs":["UniProtKB:Q9P6R8","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pre-mRNA-splicing factor cwf24 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC13E7.02","synonyms":[{"name":"Spom972h-cwf24","type":"exact"},{"name":"complexed with cdc5 protein 24 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P6R8"}


id: PR:O14275
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppr4 gene.","definition_xrefs":["UniProtKB:O14275","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pentatricopeptide repeat-containing protein 4, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC8C9.06c","synonyms":[{"name":"Spom972h-ppr4","type":"exact"}],"termid":"PR:O14275"}


id: FYPO:0005321
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetative cell is inviable contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested in mitotic metaphase.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"abnormal cell cycle arrest in mitotic metaphase","termid":"FYPO:0000620"},{"relation_name":"is_a","term_name":"abnormal cell cycle arrest in mitotic metaphase","termid":"FYPO:0000620"},{"relation_name":"is_a","term_name":"inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase","termid":"FYPO:0003128"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000631","FYPO:0001320","FYPO:0000032","FYPO:0000002","FYPO:0000004","FYPO:0000005","FYPO:0001985"],"is_obsolete":false,"name":"inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic metaphase","synonyms":[{"name":"elongated inviable mononucleate aseptate cell with mitotic cell cycle arrest in metaphase during vegetative growth","type":"exact"},{"name":"elongated inviable mononucleate aseptate vegetative cell with cell cycle arrest in mitotic metaphase","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell arrested in metaphase","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in metaphase during mitotic cell cycle","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic metaphase","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic cell cycle arrest in metaphase","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic metaphase arrest","type":"exact"},{"name":"inviable elongated mononucleate aseptate vegetative cell with mitotic nuclear division arrest in metaphase","type":"exact"},{"name":"lethal; elongated mononucleate aseptate vegetative cell with cell cycle arrest in mitotic metaphase","type":"exact"},{"name":"mitotic cell cycle arrest in metaphase with elongated inviable mononucleate aseptate cell","type":"exact"},{"name":"mitotic metaphase arrested elongated inviable mononucleate aseptate vegetative cell","type":"exact"},{"name":"nuclear division arrest in metaphase without septation (elongated cell)","type":"exact"}],"termid":"FYPO:0005321"}


id: GO:0046967
data:
  {"annotated_genes":["SJAG_04162","SJAG_01803","SJAG_01078"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[112120],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120112"},{"annotations":[93534,93535],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140209"}]},"cv_name":"biological_process","definition":"The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular transport","termid":"GO:0046907"},{"relation_name":"is_a","term_name":"transmembrane transport","termid":"GO:0055085"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01078":null,"SJAG_01803":null,"SJAG_04162":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0055085","GO:0006810"],"is_obsolete":false,"name":"cytosol to endoplasmic reticulum transport","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"cytosol to ER transport","type":"exact"}],"termid":"GO:0046967","terms_by_termid":{"GO:0120112":null,"GO:0140209":null}}


id: PBO:0004935
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4.1.1.48","termid":"PBO:0004935"}


id: PBO:0049019
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GPN-loop GTPase 1","termid":"PBO:0049019"}


id: FYPO:0003777
data:
  {"alleles_by_uniquename":{"SJAG_01745:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01745","name":"lem2delta","uniquename":"SJAG_01745:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[118953],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0003657"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization during vegetative growth","termid":"FYPO:0000443"},{"relation_name":"is_a","term_name":"abnormal protein localization to endoplasmic reticulum","termid":"FYPO:0006377"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01050":null,"SJAG_01745":null},"genotype_count":1,"genotypes_by_uniquename":{"lem2delta":{"display_name":"lem2delta","display_uniquename":"lem2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01745:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0001985"],"is_obsolete":false,"name":"abnormal protein localization to endoplasmic reticulum during vegetative growth","references_by_uniquename":{"PMID:32109380":null},"single_locus_annotated_genes":["SJAG_01745"],"single_locus_genotype_uniquenames":["lem2delta"],"synonyms":[{"name":"abnormal protein localisation to endoplasmic reticulum during vegetative growth","type":"exact"},{"name":"abnormal protein localization to ER during vegetative growth","type":"exact"},{"name":"abnormal protein localization to endoplasmic reticulum during mitotic cell cycle","type":"related"}],"termid":"FYPO:0003777","terms_by_termid":{"FYECO:0000137":null,"FYPO:0003657":null,"FYPO_EXT:0000001":null}}


id: PBO:0064990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline rich mitotic checkpoint control factor","termid":"PBO:0064990"}


id: PBO:0050584
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heparan sulfate 6-O-sulfotransferase 1 pseudogene 1","termid":"PBO:0050584"}


id: PBO:0079774
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP-glucose 6-dehydrogenase","termid":"PBO:0079774"}


id: MOD:01933
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links four L-lysine residues to form desmosine.","definition_xrefs":["PubMed:14109939","PubMed:13941623","ChEBI:37629","PubMed:5839176","RESID:AA0587","PubMed:14109938"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyridinyl ring crosslinked residues","termid":"MOD:01425"},{"relation_name":"is_a","term_name":"crosslinked L-lysine residue","termid":"MOD:02051"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"desmosine","synonyms":[{"name":"4-[(4S)-4-amino-4-carboxybutyl]-1-[(5S)-5-amino-5-carboxypentyl]-3,5-bis[(3S)-3-amino-3-carboxypropyl]pyridinium","type":"exact"},{"name":"6-[4-(4-amino-4-carboxybutyl)-3,5-bis(3-amino-3-carboxypropyl)pyridinio]norleucine","type":"exact"},{"name":"desmosine","type":"exact"}],"termid":"MOD:01933"}


id: PBO:0087116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosome biogenesis factor; nucleolar protein associated with pre-rRNA components of the 90S preribosome, required for cleavage of pre-rRNA at A0, A1 and A2 sites; interacts with RNA helicase Dhr2p and RNA helicase-like protein Utp25p; required for incorporation of Utp25p into preribosomes","termid":"PBO:0087116"}


id: FYPO:0000990
data:
  {"alleles_by_uniquename":{"SJAG_00426:allele-1":{"allele_type":"amino_acid_mutation","description":"P363S","gene_uniquename":"SJAG_00426","name":"bbl1-P363S","uniquename":"SJAG_00426:allele-1"},"SJAG_01956:allele-1":{"allele_type":"amino_acid_mutation","description":"E405K ts","gene_uniquename":"SJAG_01956","name":"nuc2-1051","uniquename":"SJAG_01956:allele-1"},"SJAG_02621:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02621","name":"ago1delta","uniquename":"SJAG_02621:allele-1"},"SJAG_03118:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03118","name":"leo1delta","uniquename":"SJAG_03118:allele-1"},"SJAG_03351:allele-1":{"allele_type":"amino_acid_mutation","description":"A186T ts","gene_uniquename":"SJAG_03351","name":"cut23-415","uniquename":"SJAG_03351:allele-1"},"SJAG_03575:allele-1":{"allele_type":"amino_acid_mutation","description":"E548K ts","gene_uniquename":"SJAG_03575","name":"apc2-361","uniquename":"SJAG_03575:allele-1"},"SJAG_03689:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03689","name":"dcr1delta","uniquename":"SJAG_03689:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"multi_locus_phenotype":[{"annotations":[119223,119225],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0004982"},{"annotations":[119226,119224],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0004573"}],"single_locus_phenotype":[{"annotations":[119168],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0004695"},{"annotations":[119167],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0002227"},{"annotations":[119211],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0004982"},{"annotations":[119140,119141,119139],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0001327"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of a specific substance measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered level of substance in cell","termid":"FYPO:0000989"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00426":null,"SJAG_01956":null,"SJAG_02621":null,"SJAG_03118":null,"SJAG_03198":null,"SJAG_03351":null,"SJAG_03575":null,"SJAG_03689":null},"genotype_count":7,"genotypes_by_uniquename":{"ago1delta__leo1delta":{"display_name":"ago1delta leo1delta","display_uniquename":"ago1delta__leo1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02621:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_03118:allele-1","expression":"Null"}]}]},"apc2-361-E548K_ts-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"apc2-361(E548K ts)","display_uniquename":"apc2-361-E548K_ts-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03575:allele-1","expression":"Not assayed or wild type"}]}]},"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"bbl1-P363S(aa)","display_uniquename":"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00426:allele-1","expression":"Not assayed or wild type"}]}]},"cut23-415-A186T_ts-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"cut23-415(A186T ts)","display_uniquename":"cut23-415-A186T_ts-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03351:allele-1","expression":"Not assayed or wild type"}]}]},"dcr1delta":{"display_name":"dcr1delta","display_uniquename":"dcr1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03689:allele-1","expression":"Null"}]}]},"dcr1delta__leo1delta":{"display_name":"dcr1delta leo1delta","display_uniquename":"dcr1delta__leo1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03689:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_03118:allele-1","expression":"Null"}]}]},"nuc2-1051-E405K_ts-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"nuc2-1051(E405K ts)","display_uniquename":"nuc2-1051-E405K_ts-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01956:allele-1","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"multi_locus_annotated_genes":["SJAG_03118","SJAG_02621","SJAG_03689"],"name":"increased level of substance in cell","references_by_uniquename":{"PMID:23786411":null,"PMID:25318672":null,"PMID:35226668":null},"single_locus_annotated_genes":["SJAG_01956","SJAG_03689","SJAG_03351","SJAG_03575","SJAG_00426"],"single_locus_genotype_uniquenames":["nuc2-1051-E405K_ts-amino_acid_mutation-expression-not_assayed_or_wild_type","cut23-415-A186T_ts-amino_acid_mutation-expression-not_assayed_or_wild_type","bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type","dcr1delta","apc2-361-E548K_ts-amino_acid_mutation-expression-not_assayed_or_wild_type"],"synonyms":[{"name":"increased accumulation of substance in cell","type":"related"}],"termid":"FYPO:0000990","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000005":null,"FYECO:0000006":null,"FYECO:0000137":null,"FYECO:0000162":null,"FYPO:0001327":null,"FYPO:0002227":null,"FYPO:0004573":null,"FYPO:0004695":null,"FYPO:0004982":null}}


id: MONDO:0017606
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete facial nerve palsy due to herpes zoster infection (obsolete MONDO:0017606)","termid":"MONDO:0017606","xrefs":{"Monarch":{"xref_id":"0017606"}}}


id: SO:0001897
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A pseudogene contained within a transposable element.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pseudogene","termid":"SO:0000336"},{"relation_name":"part_of","term_name":"transposable_element","termid":"SO:0000101"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transposable_element_pseudogene","synonyms":[{"name":"transposable element pseudogene","type":"exact"}],"termid":"SO:0001897"}


id: PBO:0061246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nitric oxide synthase 1","termid":"PBO:0061246"}


id: PBO:0065074
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PRICKLE2 antisense RNA 3","termid":"PBO:0065074"}


id: PBO:0078435
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gly (anticodon TCC) 2-5","termid":"PBO:0078435"}


id: GO:0010423
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.","definition_xrefs":["PMID:16857903"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of brassinosteroid biosynthetic process","termid":"GO:0010422"},{"relation_name":"is_a","term_name":"negative regulation of steroid hormone biosynthetic process","termid":"GO:0090032"},{"relation_name":"negatively_regulates","term_name":"brassinosteroid biosynthetic process","termid":"GO:0016132"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"negatively_regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"negative regulation of brassinosteroid biosynthetic process","termid":"GO:0010423"}


id: GO:0010473
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol.","definition_xrefs":["PMID:17485667"],"direct_ancestors":[{"relation_name":"is_a","term_name":"guanylyltransferase activity","termid":"GO:0070568"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016779"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016779","GO:0003674"],"is_obsolete":false,"name":"GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity","termid":"GO:0010473"}


id: PBO:0042503
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cadherin related 23","termid":"PBO:0042503"}


id: PBO:0045450
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dihydropyrimidinase like 3","termid":"PBO:0045450"}


id: PBO:0030199
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_cytochalasin_B","termid":"PBO:0030199"}


id: GO:0033393
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide catabolic process","termid":"GO:0000272"},{"relation_name":"is_a","term_name":"homogalacturonan metabolic process","termid":"GO:0010394"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"homogalacturonan catabolic process","secondary_identifiers":["MetaCyc:PWY-1081"],"synonyms":[{"name":"homogalacturonan breakdown","type":"exact"},{"name":"homogalacturonan catabolism","type":"exact"},{"name":"homogalacturonan degradation","type":"exact"}],"termid":"GO:0033393"}


id: GO:1990877
data:
  {"annotated_genes":["SJAG_04910","SJAG_02231"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[95852,106902],"is_not":false,"summary":null,"term":"GO:1990877"}]},"cv_name":"cellular_component","definition":"A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains follicular (FLCN) and either follicular interacting protein 1 (FNIP1) or FNIP2.","definition_xrefs":["PMID:24095279","PMID:26387955","PMID:34805795","GOC:rn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"GTPase activator complex","termid":"GO:1902773"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02231":null,"SJAG_04910":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"FNIP-folliculin RagC/D GAP","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"BFC complex","type":"exact"},{"name":"FLCN-FNIP1 complex","type":"exact"},{"name":"FLCN-FNIP2 complex","type":"exact"},{"name":"FNIP-Folliculin RagC/D GAP complex","type":"exact"},{"name":"Lst4-Lst7 complex","type":"exact"}],"termid":"GO:1990877","terms_by_termid":{"GO:1990877":null}}


id: GO:0042567
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development.","definition_xrefs":["GOC:jl","PMID:12239079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"insulin-like growth factor binding protein complex","termid":"GO:0016942"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005576"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005576","GO:0032991"],"is_obsolete":false,"name":"insulin-like growth factor ternary complex","synonyms":[{"name":"IGF ternary complex","type":"exact"}],"termid":"GO:0042567"}


id: PBO:0108525
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine zipper like post translational regulator 1","termid":"PBO:0108525"}


id: PBO:0089960
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"shelterin complex telomere binding subunit Rap1","termid":"PBO:0089960"}


id: PBO:0025441
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G6PD deficiency","termid":"PBO:0025441"}


id: PBO:0059412
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein S35 pseudogene 2","termid":"PBO:0059412"}


id: GO:0043975
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete histone H3-K36 acetylation (obsolete GO:0043975)","synonyms":[{"name":"histone H3 acetylation at K36","type":"exact"},{"name":"histone H3K36 acetylation","type":"exact"}],"termid":"GO:0043975"}


id: PBO:0046694
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ethanolamine kinase 2","termid":"PBO:0046694"}


id: PBO:0066354
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"reticulocalbin 1 pseudogene 2","termid":"PBO:0066354"}


id: MONDO:0700112
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any visceral hetetotaxy in which the cause of the disease is a mutation in the NODAL gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"visceral heterotaxy","termid":"MONDO:0018677"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterotaxy, visceral, 5, autosomal","secondary_identifiers":["OMIM:270100","MEDGEN:501198","UMLS:C3495537"],"synonyms":[{"name":"HTX5","type":"exact"},{"name":"NODAL visceral heterotaxy","type":"exact"},{"name":"SIV","type":"exact"},{"name":"situs inversus viscerum","type":"exact"},{"name":"visceral heterotaxy caused by mutation in NODAL","type":"exact"}],"termid":"MONDO:0700112","xrefs":{"Monarch":{"xref_id":"0700112"}}}


id: MONDO:0030970
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 106, susceptibility to viral infections","secondary_identifiers":["MEDGEN:1804672","OMIM:619935","UMLS:C5677009"],"synonyms":[{"name":"IFNAR1 deficiency","type":"exact"},{"name":"IMD106","type":"exact"},{"name":"immunodeficiency 106, susceptibility to viral infections","type":"exact"}],"termid":"MONDO:0030970","xrefs":{"Monarch":{"xref_id":"0030970"}}}


id: GO:0006382
data:
  {"annotated_genes":["SJAG_00352","SJAG_04380","SJAG_04189"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[100867,58974,73510],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0002100"}]},"cv_name":"biological_process","definition":"The conversion of an adenosine residue to inosine in an RNA molecule by deamination.","definition_xrefs":["PMID:11092837"],"direct_ancestors":[{"relation_name":"is_a","term_name":"base conversion or substitution editing","termid":"GO:0016553"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00352":null,"SJAG_04189":null,"SJAG_04380":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"adenosine to inosine editing","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-75064"],"termid":"GO:0006382","terms_by_termid":{"GO:0002100":null}}


id: MONDO:0016659
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"8p23.1 duplication syndrome is a rare chromosomal anomaly syndrome, resulting from the partial duplication of the short arm of chromosome 8, with a highly variable phenotype, principally characterized by mild to moderate developmental delay, intellectual disability, mild facial dysmorphism (incl. prominent forehead, arched eyebrows, broad nasal bridge, upturned nares, cleft lip and/or palate) and congenital cardiac anomalies (e.g., atrioventricular septal defect). Other reported features include macrocephaly, behavioral abnormalities (e.g., attention deficit disorder), seizures, hypotonia and ocular and digital anomalies (poly/syndactyly).","definition_xrefs":["Orphanet:251076"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of the short arm of chromosome 8","termid":"MONDO:0016945"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"8p23.1 duplication syndrome","secondary_identifiers":["UMLS:C4707330","SCTID:765140006","GARD:10304","MEDGEN:1645138","DECIPHER:85"],"synonyms":[{"name":"dup(8)(p23.1p23.1)","type":"exact"},{"name":"trisomy 8p23.1","type":"exact"}],"termid":"MONDO:0016659","xrefs":{"Monarch":{"xref_id":"0016659"}}}


id: GO:0071111
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H+.","definition_xrefs":["EC:3.1.4.52","RHEA:24902"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphoric diester hydrolase activity","termid":"GO:0008081"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016788","GO:0016787"],"is_obsolete":false,"name":"cyclic-guanylate-specific phosphodiesterase activity","secondary_identifiers":["MetaCyc:RXN0-4181","KEGG_REACTION:R08991"],"synonyms":[{"name":"PDEA1","type":"related"},{"name":"VieA","type":"related"},{"name":"c-di-GMP phosphodiesterase activity","type":"related"},{"name":"c-di-GMP-specific phosphodiesterase activity","type":"related"},{"name":"cyclic bis(3->5')diguanylate phosphodiesterase activity","type":"related"},{"name":"phosphodiesterase A1 activity","type":"related"}],"termid":"GO:0071111"}


id: PBO:0084562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Membrane bound guanine nucleotide exchange factor; also known as a GEF or GDP-release factor; indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1; thermosensitivity of the cdc25-5 mutant is functionally complemented by human RASGRF1 or by a fragment of human SOS1 comprising the CDC25-related catalytic domain","termid":"PBO:0084562"}


id: PATO:0002297
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A cellular motility which is lower relative to the normal or average.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"cellular motility","termid":"PATO:0001488"},{"relation_name":"is_a","term_name":"decreased object quality","termid":"PATO:0002303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased cellular motility","termid":"PATO:0002297"}


id: GO:0019362
data:
  {"annotated_genes":["SJAG_00839","SJAG_04495","SJAG_03298","SJAG_00957","SJAG_04152","SJAG_00685","SJAG_04192","SJAG_02154","SJAG_02696","SJAG_03946","SJAG_02796","SJAG_03174","SJAG_01012","SJAG_00027","SJAG_04467","SJAG_02148","SJAG_02107","SJAG_06622","SJAG_02135","SJAG_02191","SJAG_03669","SJAG_03660","SJAG_01824","SJAG_03852","SJAG_00605","SJAG_02009","SJAG_00522","SJAG_01582","SJAG_04362","SJAG_02945","SJAG_00461","SJAG_02853","SJAG_03091","SJAG_03903","SJAG_02618","SJAG_00633","SJAG_03373","SJAG_00070","SJAG_03828","SJAG_03934","SJAG_01566","SJAG_05314","SJAG_04048","SJAG_02785","SJAG_02369","SJAG_04693","SJAG_01310","SJAG_04263","SJAG_01500","SJAG_02889","SJAG_06621","SJAG_00409","SJAG_00501","SJAG_02297","SJAG_04334","SJAG_02462","SJAG_01539"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[116092,97749,109147,103393,94284,105588,109146,94773,98022,103136,109142,77638,105219,109143,109144,105218,109145,105587,105217,109141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061621"},{"annotations":[88367],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061613"},{"annotations":[96316],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043490"},{"annotations":[70483],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034356"},{"annotations":[77261,74415,112832],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009435"},{"annotations":[79910],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034355"},{"annotations":[72164],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019677"},{"annotations":[58460,68865,66551],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019674"},{"annotations":[72166],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006734"},{"annotations":[74293,69875,79613,74529],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006116"},{"annotations":[94868,94867],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006735"},{"annotations":[70863,79636,77712],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006741"},{"annotations":[72167],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006742"},{"annotations":[73628],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006739"},{"annotations":[72857,75818],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:0045820"},{"annotations":[103187,66101,89067],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046496"},{"annotations":[88779,109366,90415],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019358"},{"annotations":[67960],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006098"},{"annotations":[104110,108183,74286,72891,73569],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0009052"},{"annotations":[80131,72862,96650,97941,96739],"is_not":false,"rel_names":["part_of","is_a"],"summary":null,"term":"GO:0009051"},{"annotations":[89451],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1905857"},{"annotations":[69868],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0006110"},{"annotations":[75817],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0043456"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide metabolic process","termid":"GO:0009117"},{"relation_name":"is_a","term_name":"pyridine-containing compound metabolic 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id: GO:0042577
data:
  {"annotated_genes":["SJAG_02763","SJAG_04986","SJAG_00920","SJAG_02356"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71058,75978,76651],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008195"},{"annotations":[79676],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042392"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatase activity","termid":"GO:0016791"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00920":null,"SJAG_02356":null,"SJAG_02763":null,"SJAG_04986":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0016788","GO:0003674"],"is_obsolete":false,"name":"lipid phosphatase activity","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0042577","terms_by_termid":{"GO:0008195":null,"GO:0042392":null}}


id: PBO:0072337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S26 pseudogene 23","termid":"PBO:0072337"}


id: PATO:0001773
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A quality inhering in a bearer by virtue of the bearer's having only one phase or stage.","definition_xrefs":["hefreedictionary.com:hefreedictionary.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phase","termid":"PATO:0000083"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monophasic","termid":"PATO:0001773"}


id: PBO:0077956
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ala (anticodon AGC) 12-3","termid":"PBO:0077956"}


id: GO:0072522
data:
  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chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biosynthetic process","termid":"GO:0009058"},{"relation_name":"is_a","term_name":"purine-containing compound metabolic 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id: MONDO:1010548
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Diprosopus that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diprosopus, non-human animal","termid":"MONDO:1010045"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diprosopus, cattle","secondary_identifiers":["OMIA:000290-9913"],"termid":"MONDO:1010548","xrefs":{"Monarch":{"xref_id":"1010548"}}}


id: PBO:0035850
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  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_histone_H3-K9_dimethylation_at_rDNA_during_vegetative_growth","termid":"PBO:0035850"}


id: MONDO:0014705
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any craniosynostosis in which the cause of the disease is a mutation in the ZIC1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isolated oxycephaly","termid":"MONDO:0018971"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"craniosynostosis 6","secondary_identifiers":["UMLS:C4225269","GARD:18048","OMIM:616602","MEDGEN:904675","Orphanet:672985"],"synonyms":[{"name":"CRS6","type":"related"},{"name":"ZIC1 craniosynostosis","type":"exact"},{"name":"craniosynostosis 6","type":"exact"},{"name":"craniosynostosis caused by mutation in ZIC1","type":"exact"},{"name":"craniosynostosis type 6","type":"exact"}],"termid":"MONDO:0014705","xrefs":{"Monarch":{"xref_id":"0014705"}}}


id: GO:1900141
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.","definition_xrefs":["GOC:TermGenie","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of glial cell apoptotic process","termid":"GO:0034350"},{"relation_name":"regulates","term_name":"oligodendrocyte apoptotic process","termid":"GO:0097252"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of oligodendrocyte apoptotic process","synonyms":[{"name":"regulation of oligodendrocyte apoptosis","type":"narrow"}],"termid":"GO:1900141"}


id: GO:0021543
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.","definition_xrefs":["GOC:dgh","GO_REF:0000021","GOC:cls","GOC:dph","GOC:jid","PMID:12626695"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"telencephalon development","termid":"GO:0021537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pallium development","termid":"GO:0021543"}


id: GO:0071042
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  {"annotated_genes":["SJAG_00854","SJAG_04153","SJAG_04321","SJAG_03179","SJAG_04084","SJAG_04818","SJAG_01521","SJAG_04006","SJAG_01818","SJAG_01191","SJAG_04824","SJAG_03745"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92011,92842,95672,97003,101836,104158,105023,106224,107210,115187,115628,118043],"is_not":false,"summary":null,"term":"GO:0071042"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.","definition_xrefs":["PMID:17643380","GOC:krc","PMID:16431988","PMID:18644474","PMID:15145828","PMID:15828860","GOC:dgf","PMID:18000032"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyadenylation-dependent mRNA catabolic process","termid":"GO:0071047"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00854":null,"SJAG_01191":null,"SJAG_01521":null,"SJAG_01818":null,"SJAG_03179":null,"SJAG_03745":null,"SJAG_04006":null,"SJAG_04084":null,"SJAG_04153":null,"SJAG_04321":null,"SJAG_04818":null,"SJAG_04824":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0016071"},{"rel_name":"regulates","termid":"GO:0016071"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"positively_regulates","termid":"GO:0016071"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0016071","GO:0008150"],"is_obsolete":false,"name":"nuclear polyadenylation-dependent mRNA catabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"nuclear poly(A)-dependent mRNA catabolic process","type":"related"}],"termid":"GO:0071042","terms_by_termid":{"GO:0071042":null}}


id: GO:0034871
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  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity (obsolete GO:0034871)","termid":"GO:0034871"}


id: PBO:0040505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"apoptosis and caspase activation inhibitor","termid":"PBO:0040505"}


id: PBO:0018269
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial processing peptidase (MPP) complex beta subunit Mas1 (predicted)","termid":"PBO:0018269"}


id: PBO:0077777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOMM40 pseudogene 4","termid":"PBO:0077777"}


id: PBO:0060426
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAB1 pseudogene 1","termid":"PBO:0060426"}


id: PBO:0002291
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER protein translocation subcomplex subunit Sec72 (predicted)","termid":"PBO:0002291"}


id: MONDO:1010960
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chronic myelomonocytic leukemia that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"canine leukemia","termid":"MONDO:0700144"},{"relation_name":"is_a","term_name":"chronic myelomonocytic leukemia, non-human animal","termid":"MONDO:1010222"},{"relation_name":"is_a","term_name":"cancer, dog","termid":"MONDO:1012570"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic myelomonocytic leukemia, dog","secondary_identifiers":["OMIA:002299-9615"],"termid":"MONDO:1010960","xrefs":{"Monarch":{"xref_id":"1010960"}}}


id: GO:0098887
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurotransmitter receptor transport to postsynaptic membrane","termid":"GO:0098969"},{"relation_name":"is_a","term_name":"neurotransmitter receptor transport, endosome to plasma membrane","termid":"GO:0099639"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0016192","GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"neurotransmitter receptor transport, endosome to postsynaptic membrane","synonyms":[{"name":"postsynaptic neurotransmitter receptor endosomal trafficking","type":"broad"}],"termid":"GO:0098887"}


id: GO:1990811
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  {"annotated_genes":["SJAG_03062","SJAG_01546","SJAG_03116"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[73801,96524,102799],"is_not":false,"summary":null,"term":"GO:1990811"}]},"cv_name":"cellular_component","definition":"A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.","definition_xrefs":["PMID:29021344","PMID:25987607"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01546":null,"SJAG_03062":null,"SJAG_03116":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"MWP complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"Msd1-Wdr8-Pkl1 complex","type":"exact"}],"termid":"GO:1990811","terms_by_termid":{"GO:1990811":null}}


id: GO:0015307
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  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out).","definition_xrefs":["TC:2.A.1.2.-","TC:2.A.1.3.-"],"gene_count":0,"genotype_count":0,"name":"obsolete drug:proton antiporter activity (obsolete GO:0015307)","synonyms":[{"name":"carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity","type":"narrow"},{"name":"drug:hydrogen antiporter activity","type":"exact"}],"termid":"GO:0015307"}


id: PBO:0048354
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyceraldehyde 3 phosphate dehydrogenase pseudogene 65","termid":"PBO:0048354"}


id: PR:O13679
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC737.05 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13679"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C737.05 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC737.05","synonyms":[{"name":"Spom972h-SPCC737.05","type":"exact"}],"termid":"PR:O13679"}


id: MONDO:0016454
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare axonal hereditary motor and sensory neuropathy characterized by infantile onset of slowly progressive distal motor weakness and atrophy (more severe in legs and moderate in arms) with mildly delayed motor development, hypotonia, and distal sensory impairment of all sensory modalities.","definition_xrefs":["Orphanet:228374"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease type 2","termid":"MONDO:0018993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease type 2B5","secondary_identifiers":["MEDGEN:1668955","GARD:17153","UMLS:C4749824","icd11.foundation:1603286685"],"synonyms":[{"name":"AR-CMT2B5","type":"exact"},{"name":"Charcot-Marie-Tooth disease type 2B5","type":"exact"},{"name":"SEOAN due to NEFL deficiency","type":"exact"},{"name":"autosomal recessive Charcot-Marie-Tooth disease type 2B5","type":"exact"},{"name":"severe early-onset axonal neuropathy due to NEFL deficiency","type":"exact"},{"name":"severe early-onset axonal neuropathy due to light neurofilament subunit deficiency","type":"exact"}],"termid":"MONDO:0016454","xrefs":{"Monarch":{"xref_id":"0016454"}}}


id: GO:0001671
data:
  {"annotated_genes":["SJAG_00066","SJAG_02045","SJAG_00796","SJAG_01121","SJAG_03221","SJAG_00901","SJAG_01708","SJAG_01597"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[57254,66856,74034,78866,91154,96002,107421,110056],"is_not":false,"summary":null,"term":"GO:0001671"}]},"cv_name":"molecular_function","definition":"Binds to and increases the activity of an ATP hydrolysis activity.","definition_xrefs":["GOC:ajp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ATPase regulator activity","termid":"GO:0060590"},{"relation_name":"is_a","term_name":"molecular function activator activity","termid":"GO:0140677"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00066":null,"SJAG_00796":null,"SJAG_00901":null,"SJAG_01121":null,"SJAG_01597":null,"SJAG_01708":null,"SJAG_02045":null,"SJAG_03221":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140677"},{"rel_name":"is_a","termid":"GO:0098772"}],"interesting_parent_ids":["GO:0003674","GO:0140677","GO:0098772"],"is_obsolete":false,"name":"ATPase activator activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-5251955","Reactome:R-HSA-5251959"],"synonyms":[{"name":"ATPase stimulator activity","type":"exact"}],"termid":"GO:0001671","terms_by_termid":{"GO:0001671":null}}


id: PBO:0055969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LRR binding FLII interacting protein 1 pseudogene 1","termid":"PBO:0055969"}


id: PBO:0116227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane queuine and queuosine transmembrane importer, Qtp1","termid":"PBO:0116227"}


id: GO:0180007
data:
  {"annotated_genes":["SJAG_03624","SJAG_02389"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[95595,96951],"is_not":false,"summary":null,"term":"GO:0180007"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 5) + H2O = RNA polymerase II large subunit + phosphate.","definition_xrefs":["PMID:22622228"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA polymerase II CTD heptapeptide repeat phosphatase activity","termid":"GO:0008420"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02389":null,"SJAG_03624":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0004721"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140096","GO:0003824","GO:0016788","GO:0004721","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"RNA polymerase II C-terminal domain S5 phosphatase activity","type":"exact"}],"termid":"GO:0180007","terms_by_termid":{"GO:0180007":null}}


id: PBO:0064619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"POU class 6 homeobox 1","termid":"PBO:0064619"}


id: PBO:0061740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurexophilin and PC-esterase domain family member 3","termid":"PBO:0061740"}


id: PBO:0056330
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitogen-activated protein kinase kinase kinase 11","termid":"PBO:0056330"}


id: GO:0060095
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.","definition_xrefs":["GOC:dms","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of synaptic transmission, glycinergic","termid":"GO:0060094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"zinc potentiation of synaptic transmission, glycinergic","synonyms":[{"name":"zinc potentiation of glycinergic synaptic transmission","type":"exact"}],"termid":"GO:0060095"}


id: PBO:0087666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and regulators of sterol biosynthesis for ubiquitin-mediated degradation; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids","termid":"PBO:0087666"}


id: PBO:0086723
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; non-essential gene; interacts genetically with CHS5, a gene involved in chitin biosynthesis","termid":"PBO:0086723"}


id: GO:0047031
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ = diethyl 2-methyl-3-oxosuccinate + H+ + NADPH.","definition_xrefs":["EC:1.1.1.229","RHEA:21008"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"diethyl 2-methyl-3-oxosuccinate reductase activity","secondary_identifiers":["MetaCyc:1.1.1.229-RXN","KEGG_REACTION:R04387"],"synonyms":[{"name":"diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity","type":"related"}],"termid":"GO:0047031"}


id: GO:0060994
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state.","definition_xrefs":["GOC:mtg_kidney_jan10","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of transcription from RNA polymerase II promoter involved in kidney development (obsolete GO:0060994)","termid":"GO:0060994"}


id: GO:0003331
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of extracellular matrix constituent secretion","termid":"GO:0003330"},{"relation_name":"is_a","term_name":"positive regulation of extracellular matrix organization","termid":"GO:1903055"},{"relation_name":"is_a","term_name":"positive regulation of secretion by cell","termid":"GO:1903532"},{"relation_name":"positively_regulates","term_name":"extracellular matrix constituent secretion","termid":"GO:0070278"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of extracellular matrix constituent secretion","termid":"GO:0003331"}


id: PBO:0050388
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A3 pseudogene 12","termid":"PBO:0050388"}


id: MONDO:0004242
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"peptic ulcer disease","termid":"MONDO:0004247"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"active peptic ulcer disease","secondary_identifiers":["SCTID:74474003","ICD9:578.9","MESH:D010438","DOID:749","SCTID:64121000"],"synonyms":[{"name":"GI bleeding","type":"related"}],"termid":"MONDO:0004242","xrefs":{"Monarch":{"xref_id":"0004242"}}}


id: PBO:0014241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial calcium uniporter regulator (predicted)","termid":"PBO:0014241"}


id: PBO:0086156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for pre-rRNA processing; associated with the 90S pre-ribosome and 43S small ribosomal subunit precursor; interacts with U3 snoRNA; binds G-quadruplex (G4) structures in DNA; deletion mutant has synthetic fitness defect with an sgs1 deletion mutant","termid":"PBO:0086156"}


id: GO:0001804
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of type III hypersensitivity","termid":"GO:0001803"},{"relation_name":"is_a","term_name":"negative regulation of hypersensitivity","termid":"GO:0002884"},{"relation_name":"is_a","term_name":"negative regulation of myeloid leukocyte mediated immunity","termid":"GO:0002887"},{"relation_name":"is_a","term_name":"negative regulation of immunoglobulin mediated immune response","termid":"GO:0002890"},{"relation_name":"negatively_regulates","term_name":"type III hypersensitivity","termid":"GO:0001802"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of type III hypersensitivity","synonyms":[{"name":"down regulation of type III hypersensitivity","type":"exact"},{"name":"down-regulation of type III hypersensitivity","type":"exact"},{"name":"downregulation of type III hypersensitivity","type":"exact"},{"name":"inhibition of type III hypersensitivity","type":"narrow"}],"termid":"GO:0001804"}


id: GO:2000669
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.","definition_xrefs":["GOC:obol","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of leukocyte apoptotic process","termid":"GO:2000107"},{"relation_name":"is_a","term_name":"regulation of dendritic cell apoptotic process","termid":"GO:2000668"},{"relation_name":"negatively_regulates","term_name":"dendritic cell apoptotic process","termid":"GO:0097048"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of dendritic cell apoptotic process","synonyms":[{"name":"negative regulation of dendritic cell apoptosis","type":"narrow"}],"termid":"GO:2000669"}


id: PBO:0086302
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with a role in UDP-galactose transport to the Golgi lumen; has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1","termid":"PBO:0086302"}


id: PBO:0047200
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 217 member A","termid":"PBO:0047200"}


id: PBO:0081561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 485","termid":"PBO:0081561"}


id: GO:0040005
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.","definition_xrefs":["GOC:bf","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molting cycle process","termid":"GO:0022404"},{"relation_name":"part_of","term_name":"molting cycle, chitin-based cuticle","termid":"GO:0007591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chitin-based cuticle attachment to epithelium","synonyms":[{"name":"cuticular attachment to epithelium","type":"broad"}],"termid":"GO:0040005"}


id: PBO:0051880
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ISY1 splicing factor homolog","termid":"PBO:0051880"}


id: GO:1904758
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location within a new growing cell tip.","definition_xrefs":["GO_REF:0000087","GOC:TermGenie","PMID:19431238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to growing cell tip","termid":"GO:1902486"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"protein localization to new growing cell tip","synonyms":[{"name":"protein localisation in new growing cell tip","type":"exact"},{"name":"protein localisation to new growing cell tip","type":"exact"},{"name":"protein localization in new growing cell tip","type":"exact"},{"name":"protein localization to new cell tip after activation of bipolar cell growth","type":"exact"},{"name":"protein localization to new growing cell end","type":"exact"},{"name":"protein localization to post-NETO new cell end","type":"exact"},{"name":"protein localization to post-NETO new cell tip","type":"exact"},{"name":"protein localization to post-new end take-off new cell tip","type":"exact"}],"termid":"GO:1904758"}


id: PR:O13795
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pof8 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13795"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein pof8 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17G6.17","synonyms":[{"name":"Spom972h-pof8","type":"exact"}],"termid":"PR:O13795"}


id: GO:0005740
data:
  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id: MONDO:0005800
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id: FYPO:0004778
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id: PBO:0082232
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id: PBO:0076120
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id: PBO:0069162
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id: MONDO:0014326
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any nemaline myopathy in which the cause of the disease is a mutation in the KLHL41 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"severe congenital nemaline myopathy","termid":"MONDO:0015735"},{"relation_name":"is_a","term_name":"intermediate nemaline myopathy","termid":"MONDO:0015736"},{"relation_name":"is_a","term_name":"typical nemaline myopathy","termid":"MONDO:0015737"},{"relation_name":"is_a","term_name":"childhood-onset nemaline myopathy","termid":"MONDO:0015738"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0002320"],"is_obsolete":false,"name":"nemaline myopathy 9","secondary_identifiers":["UMLS:C3810384","DOID:0110929","GARD:16007","OMIM:615731","MEDGEN:816714"],"synonyms":[{"name":"KLHL41 nemaline myopathy","type":"exact"},{"name":"NEM9","type":"exact"},{"name":"nemaline myopathy 9","type":"exact"},{"name":"nemaline myopathy caused by mutation in KLHL41","type":"exact"},{"name":"nemaline myopathy type 9","type":"exact"}],"termid":"MONDO:0014326","xrefs":{"Monarch":{"xref_id":"0014326"}}}


id: PBO:0060210
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mutY DNA glycosylase","termid":"PBO:0060210"}


id: GO:1990264
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.","definition_xrefs":["PMID:7501024"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-tyrosine dephosphorylation","termid":"GO:0035335"},{"relation_name":"part_of","term_name":"negative regulation of protein kinase activity","termid":"GO:0006469"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity","termid":"GO:1990264"}


id: PBO:0090716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"40S ribosomal protein S2","termid":"PBO:0090716"}


id: PBO:0041991
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 34 pseudogene 1","termid":"PBO:0041991"}


id: MONDO:0006867
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete neovascular glaucoma (obsolete MONDO:0006867)","termid":"MONDO:0006867","xrefs":{"Monarch":{"xref_id":"0006867"}}}


id: PBO:0036465
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved eukaryotic protein, human IFRD1 ortholog","termid":"PBO:0036465"}


id: MONDO:0012597
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"prostate cancer, hereditary","termid":"MONDO:0700275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"prostate cancer, hereditary, 9","secondary_identifiers":["MESH:C567031","OMIM:610997","GARD:15505","MEDGEN:369689","UMLS:C1970250"],"synonyms":[{"name":"HPC9","type":"related"},{"name":"prostate cancer, hereditary, 9","type":"exact"},{"name":"prostate cancer, hereditary, type 9","type":"exact"}],"termid":"MONDO:0012597","xrefs":{"Monarch":{"xref_id":"0012597"}}}


id: GO:1903892
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response.","definition_xrefs":["GO_REF:0000058","PMID:22013210","GOC:PARL","GOC:bf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of endoplasmic reticulum unfolded protein response","termid":"GO:1900102"},{"relation_name":"is_a","term_name":"regulation of ATF6-mediated unfolded protein response","termid":"GO:1903891"},{"relation_name":"negatively_regulates","term_name":"ATF6-mediated unfolded protein response","termid":"GO:0036500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of ATF6-mediated unfolded protein response","synonyms":[{"name":"down regulation of ATF6 branch of UPR","type":"exact"},{"name":"down regulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"down regulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"down regulation of ATF6-beta UPR branch","type":"narrow"},{"name":"down regulation of ATF6-mediated unfolded protein response","type":"exact"},{"name":"down regulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"down regulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"down regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"},{"name":"down-regulation of ATF6 branch of UPR","type":"exact"},{"name":"down-regulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"down-regulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"down-regulation of ATF6-beta UPR branch","type":"narrow"},{"name":"down-regulation of ATF6-mediated unfolded protein response","type":"exact"},{"name":"down-regulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"down-regulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"down-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"},{"name":"downregulation of ATF6 branch of UPR","type":"exact"},{"name":"downregulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"downregulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"downregulation of ATF6-beta UPR branch","type":"narrow"},{"name":"downregulation of ATF6-mediated unfolded protein response","type":"exact"},{"name":"downregulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"downregulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"downregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"},{"name":"inhibition of ATF6 branch of UPR","type":"narrow"},{"name":"inhibition of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"inhibition of ATF6-alpha UPR branch","type":"narrow"},{"name":"inhibition of ATF6-beta UPR branch","type":"narrow"},{"name":"inhibition of ATF6-mediated unfolded protein response","type":"narrow"},{"name":"inhibition of UPR signaling by ATF6 stress sensor","type":"narrow"},{"name":"inhibition of activating transcription factor 6 signaling in unfolded protein response","type":"narrow"},{"name":"inhibition of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"narrow"},{"name":"negative regulation of ATF6 branch of UPR","type":"exact"},{"name":"negative regulation of ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"negative regulation of ATF6-alpha UPR branch","type":"narrow"},{"name":"negative regulation of ATF6-beta UPR branch","type":"narrow"},{"name":"negative regulation of UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"negative regulation of activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"negative regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"}],"termid":"GO:1903892"}


id: PBO:0063778
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PHF5A pseudogene 5","termid":"PBO:0063778"}


id: PBO:0052351
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin family member 4A","termid":"PBO:0052351"}


id: PBO:0040883
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bone morphogenetic protein 7","termid":"PBO:0040883"}


id: GO:0050992
data:
  {"annotated_genes":["SJAG_04307"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[62693],"is_not":false,"summary":null,"term":"GO:0050992"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid biosynthetic process","termid":"GO:0008654"},{"relation_name":"is_a","term_name":"dimethylallyl diphosphate metabolic process","termid":"GO:0050993"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04307":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"dimethylallyl diphosphate biosynthetic process","references_by_uniquename":{"GO_REF:0000041":null},"synonyms":[{"name":"DPP biosynthesis","type":"exact"},{"name":"DPP biosynthetic process","type":"exact"},{"name":"dimethylallyl diphosphate anabolism","type":"exact"},{"name":"dimethylallyl diphosphate biosynthesis","type":"exact"},{"name":"dimethylallyl diphosphate formation","type":"exact"},{"name":"dimethylallyl diphosphate synthesis","type":"exact"},{"name":"dimethylallyl pyrophosphate biosynthesis","type":"exact"},{"name":"dimethylallyl pyrophosphate biosynthetic process","type":"exact"}],"termid":"GO:0050992","terms_by_termid":{"GO:0050992":null}}


id: PBO:0036338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metal-dependent protein hydrolase family protein, human C12orf10 ortholog","termid":"PBO:0036338"}


id: FYPO:0003201
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of primary cell septum biogenesis is decreased.","definition_xrefs":["PomBase:al","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal primary cell septum biogenesis","termid":"FYPO:0003890"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0000631","FYPO:0000032"],"is_obsolete":false,"name":"decreased rate of primary cell septum biogenesis","synonyms":[{"name":"decreased rate of primary cell septum biogenesis during mitotic cell cycle","type":"related"},{"name":"decreased rate of primary cell septum biogenesis during vegetative growth","type":"exact"},{"name":"decreased rate of primary septum biogenesis","type":"exact"},{"name":"increased duration of primary cell septum biogenesis","type":"related"},{"name":"reduced rate of primary cell septum biogenesis","type":"exact"}],"termid":"FYPO:0003201"}


id: PBO:0034783
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Hrd1 ubiquitin ligase complex synviolin family ubiquitin-protein ligase E3 subunit, Hrd1","termid":"PBO:0034783"}


id: GO:1902917
data:
  {"annotated_genes":["SJAG_04509","SJAG_00514","SJAG_01794","SJAG_02379","SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[87657,89628,90611,93246,111113],"is_not":false,"summary":null,"term":"GO:1902917"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of mating projection assembly.","definition_xrefs":["GOC:TermGenie","GOC:di","GO_REF:0000058","PMID:12455985"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mating projection assembly","termid":"GO:0031383"},{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"positive regulation of plasma membrane bounded cell projection assembly","termid":"GO:0120034"},{"relation_name":"part_of","term_name":"positive regulation of conjugation with cellular fusion","termid":"GO:0031139"},{"relation_name":"positively_regulates","term_name":"mating projection formation","termid":"GO:0031382"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00514":null,"SJAG_01794":null,"SJAG_02379":null,"SJAG_03453":null,"SJAG_04509":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"positive regulation of mating projection assembly","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"activation of mating projection assembly","type":"narrow"},{"name":"activation of mating projection biogenesis","type":"related"},{"name":"positive regulation of mating projection biogenesis","type":"related"},{"name":"up regulation of mating projection assembly","type":"exact"},{"name":"up regulation of mating projection biogenesis","type":"related"},{"name":"up-regulation of mating projection assembly","type":"exact"},{"name":"up-regulation of mating projection biogenesis","type":"related"},{"name":"upregulation of mating projection assembly","type":"exact"},{"name":"upregulation of mating projection biogenesis","type":"related"}],"termid":"GO:1902917","terms_by_termid":{"GO:1902917":null}}


id: GO:0047173
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester + apo--[retinol-binding protein]. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein, but has higher affinity for the bound form.","definition_xrefs":["RHEA:17469"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acyltransferase activity","termid":"GO:0008374"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0016746","GO:0003824"],"is_obsolete":false,"name":"phosphatidylcholine-retinol O-acyltransferase activity","secondary_identifiers":["MetaCyc:2.3.1.135-RXN","Reactome:R-HSA-975608","EC:2.3.1.135"],"synonyms":[{"name":"lecithin--retinol acyltransferase activity","type":"related"},{"name":"phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity","type":"related"},{"name":"phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity","type":"related"}],"termid":"GO:0047173"}


id: GO:0043776
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7.","definition_xrefs":["MetaCyc:RXN-8766"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methyltransferase activity","termid":"GO:0008168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0016741","GO:0003824"],"is_obsolete":false,"name":"cobalt-precorrin-6B C5-methyltransferase activity","secondary_identifiers":["RHEA:36067"],"synonyms":[{"name":"cobalt-precorrin 6B C5-methyltransferase activity","type":"exact"},{"name":"precorrin-6 methyltransferase activity","type":"exact"},{"name":"precorrin-6Y C5,15-methyltransferase (decarboxylating)","type":"broad"},{"name":"precorrin-6Y methylase","type":"broad"}],"termid":"GO:0043776"}


id: PBO:0113564
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oligosaccharyltransferase complex beta subunit, Wbp1","termid":"PBO:0113564"}


id: GO:0102376
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ = betulinic acid + 3 NADP + 4 H2O.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete lupeol 28-oxidase activity (obsolete GO:0102376)","termid":"GO:0102376"}


id: PBO:0088279
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PPPDE peptidase family deubiquitinase/desumoylase Sdu1","termid":"PBO:0088279"}


id: GO:0007179
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.","definition_xrefs":["GOC:mah","GOC:BHF","GOC:signaling"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transforming growth factor beta receptor superfamily signaling pathway","termid":"GO:0141091"},{"relation_name":"part_of","term_name":"cellular response to transforming growth factor beta stimulus","termid":"GO:0071560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"transforming growth factor beta receptor signaling pathway","secondary_identifiers":["Reactome:R-HSA-170834"],"synonyms":[{"name":"TGF-beta receptor signaling pathway","type":"exact"},{"name":"TGF-beta receptor signalling pathway","type":"exact"},{"name":"TGFbeta receptor signaling pathway","type":"exact"},{"name":"TGFbeta receptor signalling pathway","type":"exact"},{"name":"transforming growth factor beta receptor signalling pathway","type":"exact"}],"termid":"GO:0007179"}


id: MONDO:0010919
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"varicella, severe recurrent","secondary_identifiers":["MESH:C563458","MEDGEN:322202","OMIM:600670","UMLS:C1833487"],"synonyms":[{"name":"varicella, severe recurrent","type":"exact"}],"termid":"MONDO:0010919","xrefs":{"Monarch":{"xref_id":"0010919"}}}


id: PBO:0038697
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ACTB pseudogene 9","termid":"PBO:0038697"}


id: GO:0060423
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.","definition_xrefs":["GOC:mtg_lung","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anterior/posterior pattern specification","termid":"GO:0009952"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"foregut regionalization","termid":"GO:0060423"}


id: PBO:0078757
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA methyltransferase activator subunit 11-2","termid":"PBO:0078757"}


id: PBO:0061628
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nudix hydrolase 11","termid":"PBO:0061628"}


id: PR:O94312
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pdp2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94312"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PWWP domain-containing protein2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC215.07c","synonyms":[{"name":"Spom972h-pdp2","type":"exact"}],"termid":"PR:O94312"}


id: PATO:0000853
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000853 blinking reflex value (obsolete PATO:0000853)","termid":"PATO:0000853"}


id: PBO:0051410
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable 1-44","termid":"PBO:0051410"}


id: GO:1905009
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.","definition_xrefs":["PMID:7499219","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of organic acid transport","termid":"GO:0032891"},{"relation_name":"is_a","term_name":"negative regulation of transmembrane transport","termid":"GO:0034763"},{"relation_name":"is_a","term_name":"negative regulation of amino acid transport","termid":"GO:0051956"},{"relation_name":"is_a","term_name":"regulation of L-lysine import across plasma membrane","termid":"GO:1905008"},{"relation_name":"negatively_regulates","term_name":"L-lysine import across plasma membrane","termid":"GO:0097639"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0006810","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"negative regulation of L-lysine import across plasma membrane","secondary_identifiers":["GO:0010806"],"synonyms":[{"name":"down regulation of L-lysine import into cell","type":"exact"},{"name":"down-regulation of L-lysine import into cell","type":"exact"},{"name":"downregulation of L-lysine import into cell","type":"exact"},{"name":"inhibition of L-lysine import into cell","type":"narrow"},{"name":"negative regulation of L-lysine import into cell","type":"exact"},{"name":"negative regulation of lysine import","type":"broad"},{"name":"negative regulation of lysine uptake","type":"exact"}],"termid":"GO:1905009"}


id: PBO:0091152
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EKC/KEOPS complex subunit Gon7","termid":"PBO:0091152"}


id: GO:0060480
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.","definition_xrefs":["GOC:mtg_lung","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lung secretory cell differentiation","termid":"GO:0061140"},{"relation_name":"part_of","term_name":"lobar bronchus epithelium development","termid":"GO:0060481"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lung goblet cell differentiation","synonyms":[{"name":"pulmonary goblet cell differentiation","type":"exact"}],"termid":"GO:0060480"}


id: PBO:0072862
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP","termid":"PBO:0072862"}


id: PBO:0071596
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L36a pseudogene 13","termid":"PBO:0071596"}


id: PATO:0000654
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000654 alcochol value (obsolete PATO:0000654)","termid":"PATO:0000654"}


id: CHEBI:49786
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nickel(2+)","termid":"CHEBI:49786"}


id: PR:Q09748
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dnm1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09748"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynamin-related protein dnm1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC12C2.08","synonyms":[{"name":"Spom972h-dnm1","type":"exact"}],"termid":"PR:Q09748"}


id: PBO:0088212
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase","termid":"PBO:0088212"}


id: GO:0033763
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.","definition_xrefs":["EC:1.14.11.28"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"proline 3-hydroxylase activity","secondary_identifiers":["RHEA:20265","MetaCyc:1.14.11.28-RXN"],"synonyms":[{"name":"L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity","type":"related"},{"name":"P-3-H","type":"related"}],"termid":"GO:0033763"}


id: MONDO:0015556
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"maculopapular cutaneous mastocytosis","termid":"MONDO:0019316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005093","MONDO:0005570"],"is_obsolete":false,"name":"nodular urticaria pigmentosa","secondary_identifiers":["GARD:20035","MEDGEN:1843440","UMLS:C5680684","Orphanet:158772"],"termid":"MONDO:0015556","xrefs":{"Monarch":{"xref_id":"0015556"}}}


id: PBO:0069421
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 684, pseudogene","termid":"PBO:0069421"}


id: PBO:0039983
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP ribosylation factor like GTPase 5B","termid":"PBO:0039983"}


id: PBO:0024871
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific multicopy membrane protein family 1","termid":"PBO:0024871"}


id: GO:0102468
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin = UDP + wogonin 7-O-beta-D-glucuronate + H+.","definition_xrefs":["RHEA:28322"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexosyltransferase activity","termid":"GO:0016758"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"wogonin 7-O-glucuronosyltransferase activity","secondary_identifiers":["MetaCyc:RXN-14060"],"termid":"GO:0102468"}


id: MONDO:0025303
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease or disorder caused by infection with Anaplasma.","definition_xrefs":["MONDO:patterns/specific_infectious_disease_by_agent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Anaplasmataceae infectious disease","termid":"MONDO:0006922"},{"relation_name":"is_a","term_name":"tick-borne infectious disease","termid":"MONDO:0025294"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaplasmosis","secondary_identifiers":["UMLS:C0002797","ICD9:082.49","SCTID:427481004","SCTID:13906002","MESH:D000712","MEDGEN:8053","NCIT:C128425"],"synonyms":[{"name":"anaplasma caused disease or disorder","type":"exact"},{"name":"anaplasma disease or disorder","type":"exact"},{"name":"anaplasma infectious disease","type":"exact"},{"name":"anaplasmoses","type":"exact"},{"name":"human anaplasmosis","type":"exact"}],"termid":"MONDO:0025303","xrefs":{"Monarch":{"xref_id":"0025303"}}}


id: PBO:0054602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2006","termid":"PBO:0054602"}


id: PATO:0000748
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000748 discrimination value (obsolete PATO:0000748)","termid":"PATO:0000748"}


id: PBO:0092037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Glutamic acid (uuc), mitochondrial","termid":"PBO:0092037"}


id: MONDO:1010481
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Tetralogy of fallot that occurs in snow leopard.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tetralogy of fallot, non-human animal","termid":"MONDO:1010021"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetralogy of fallot, snow leopard","secondary_identifiers":["OMIA:000994-29064"],"termid":"MONDO:1010481","xrefs":{"Monarch":{"xref_id":"1010481"}}}


id: FYPO:0001980
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is normal (i.e. indistinguishable from wild type). RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.","definition_xrefs":["PomBase:mah","GO:0006396"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression phenotype","termid":"FYPO:0000142"},{"relation_name":"is_a","term_name":"normal metabolic process during vegetative growth","termid":"FYPO:0000859"},{"relation_name":"is_a","term_name":"normal RNA metabolic process","termid":"FYPO:0004850"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal RNA processing","synonyms":[{"name":"normal RNA processing during mitotic cell cycle","type":"related"},{"name":"normal RNA processing during vegetative growth","type":"exact"}],"termid":"FYPO:0001980"}


id: PBO:0046852
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fatty acid desaturase 1","termid":"PBO:0046852"}


id: PBO:0016076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Hal4","termid":"PBO:0016076"}


id: MONDO:0020050
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autosomal trisomy (obsolete MONDO:0020050)","secondary_identifiers":["Orphanet:98130","SCTID:429442006","ICD9:758.5"],"synonyms":[{"name":"autosomal duplication","type":"exact"},{"name":"chromosomal triplication","type":"related"},{"name":"trisomy","type":"broad"}],"termid":"MONDO:0020050","xrefs":{"Monarch":{"xref_id":"0020050"}}}


id: GO:1904916
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol.","definition_xrefs":["PMID:22822152","GOC:kmv","GOC:TermGenie","GO_REF:0000078"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-lysine transmembrane export from vacuole","termid":"GO:0089707"},{"relation_name":"is_a","term_name":"transmembrane transport from lysosomal lumen to cytosol","termid":"GO:0170063"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"L-lysine transmembrane transport from lysosomal lumen to cytosol","synonyms":[{"name":"transmembrane L-lysine transport from lysosomal lumen to cytosol","type":"exact"}],"termid":"GO:1904916"}


id: GO:1900329
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of mannotriose transport.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transport","termid":"GO:0051050"},{"relation_name":"is_a","term_name":"regulation of mannotriose transport","termid":"GO:1900327"},{"relation_name":"positively_regulates","term_name":"mannotriose transport","termid":"GO:2001095"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of mannotriose transport","synonyms":[{"name":"activation of mannotriose transport","type":"narrow"},{"name":"up regulation of mannotriose transport","type":"exact"},{"name":"up-regulation of mannotriose transport","type":"exact"},{"name":"upregulation of mannotriose transport","type":"exact"}],"termid":"GO:1900329"}


id: GO:1901815
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of astaxanthin.","definition_xrefs":["UniPathway:UPA00387","MetaCyc:PWY-5288","GOC:yaf","GOC:TermGenie","PMID:16434154"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xanthophyll biosynthetic process","termid":"GO:0016123"},{"relation_name":"is_a","term_name":"astaxanthin metabolic process","termid":"GO:1901813"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"astaxanthin biosynthetic process","synonyms":[{"name":"astaxanthin anabolism","type":"exact"},{"name":"astaxanthin biosynthesis","type":"exact"},{"name":"astaxanthin formation","type":"exact"},{"name":"astaxanthin synthesis","type":"exact"}],"termid":"GO:1901815"}


id: GO:0031686
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an A1 adenosine receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenosine receptor binding","termid":"GO:0031685"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"A1 adenosine receptor binding","synonyms":[{"name":"A1 adenosine receptor ligand","type":"narrow"}],"termid":"GO:0031686"}


id: MONDO:0000258
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete intestinal botulism (obsolete MONDO:0000258)","termid":"MONDO:0000258","xrefs":{"Monarch":{"xref_id":"0000258"}}}


id: GO:0046589
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates.","definition_xrefs":["EC:4.6.1.24"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA nuclease activity","termid":"GO:0004540"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674","GO:0016788","GO:0140098"],"is_obsolete":false,"name":"ribonuclease T1 activity","synonyms":[{"name":"Aspergillus oryzae ribonuclease activity","type":"narrow"},{"name":"RNase F1","type":"related"},{"name":"RNase G","type":"related"},{"name":"RNase N1 activity","type":"related"},{"name":"RNase N2 activity","type":"related"},{"name":"RNase Sa","type":"related"},{"name":"RNase T1","type":"related"},{"name":"RNase T1 activity","type":"exact"},{"name":"binase activity","type":"related"},{"name":"guanyl-specific RNase activity","type":"related"},{"name":"guanyloribonuclease activity","type":"related"},{"name":"ribonuclease C2","type":"related"},{"name":"ribonuclease Ch","type":"related"},{"name":"ribonuclease F1","type":"exact"},{"name":"ribonuclease N1","type":"related"},{"name":"ribonuclease N3","type":"related"},{"name":"ribonuclease PP1","type":"related"},{"name":"ribonuclease SA","type":"related"},{"name":"ribonuclease U1","type":"related"},{"name":"ribonuclease guaninenucleotido-2'-transferase (cyclizing)","type":"related"}],"termid":"GO:0046589"}


id: GO:0075112
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the symbiont alters a transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete symbiont-mediated perturbation of host transmembrane receptor-mediated signal transduction (obsolete GO:0075112)","synonyms":[{"name":"modulation by symbiont of host transmembrane receptor-mediated signal transduction","type":"exact"},{"name":"perturbation of host transmembrane receptor-mediated signal transduction","type":"exact"}],"termid":"GO:0075112"}


id: PBO:0053765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1010","termid":"PBO:0053765"}


id: GO:0050649
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 6beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].","definition_xrefs":["RHEA:46296","PMID:11726664"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid hydroxylase activity","termid":"GO:0008395"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"testosterone 6-beta-hydroxylase activity","synonyms":[{"name":"testosterone 6b-hydroxylase activity","type":"exact"}],"termid":"GO:0050649"}


id: GO:2000443
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of toll-like receptor signaling pathway","termid":"GO:0034121"},{"relation_name":"regulates","term_name":"toll-like receptor 21 signaling pathway","termid":"GO:0035682"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of toll-like receptor 21 signaling pathway","synonyms":[{"name":"regulation of TLR21 signaling pathway","type":"exact"},{"name":"regulation of toll-like receptor 21 signalling pathway","type":"exact"}],"termid":"GO:2000443"}


id: MONDO:0001173
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute inflammation of the fallopian tube. It is most often caused by Neisseria gonorrhoeae and Chlamydia trachomatis infections. The infections usually originate in the vagina and ascend to the fallopian tube. Symptoms include abdominal, pelvic, and lower back pain, pain during ovulation and sexual intercourse, fever, nausea, and vomiting. Complications include infertility and ectopic pregnancy.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"salpingitis","termid":"MONDO:0003619"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acute salpingitis","secondary_identifiers":["icd11.foundation:1286268784","SCTID:8912009","UMLS:C0269038","NCIT:C40120","DOID:10973","ICD10CM:N70.01","MEDGEN:82838"],"synonyms":[{"name":"salpingitis, acute","type":"exact"}],"termid":"MONDO:0001173","xrefs":{"Monarch":{"xref_id":"0001173"}}}


id: PBO:0027336
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-delayed_onset_of_replication_fork_processing","termid":"PBO:0027336"}


id: MONDO:0024392
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"balanitis","termid":"MONDO:0006672"},{"relation_name":"is_a","term_name":"anaerobic bacteria infectious disease","termid":"MONDO:0024389"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaerobic balanitis","secondary_identifiers":["UMLS:C0403764","MEDGEN:588642","SCTID:236746000"],"synonyms":[{"name":"anaerobic balanitis","type":"exact"}],"termid":"MONDO:0024392","xrefs":{"Monarch":{"xref_id":"0024392"}}}


id: PBO:0066648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ras and Rab interactor 2","termid":"PBO:0066648"}


id: GO:0047950
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 glutathione + O2 = glutathione disulfide + H2O2.","definition_xrefs":["RHEA:24112","EC:1.8.3.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor","termid":"GO:0016670"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"glutathione oxidase activity","secondary_identifiers":["MetaCyc:GLUTATHIONE-OXIDASE-RXN","KEGG_REACTION:R00120"],"synonyms":[{"name":"glutathione:oxygen oxidoreductase activity","type":"related"}],"termid":"GO:0047950"}


id: PBO:0002319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IMPACT homolog, translational regulator (predicted)","termid":"PBO:0002319"}


id: GO:0090712
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The end of the outer hair cell which receives and transmits neural signals.","definition_xrefs":["PMID:12845523","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell pole","termid":"GO:0060187"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"basal pole of outer hair cell","termid":"GO:0090712"}


id: MOD:01278
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Other -","definition_xrefs":["Unimod:253#K","PubMed:11283024"],"direct_ancestors":[{"relation_name":"is_a","term_name":"crotonaldehyde","termid":"MOD:00576"},{"relation_name":"is_a","term_name":"modified L-lysine residue","termid":"MOD:00912"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crotonaldehyde - site K","synonyms":[{"name":"Crotonaldehyde","type":"related"}],"termid":"MOD:01278"}


id: PBO:0058091
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR4307 host gene","termid":"PBO:0058091"}


id: MONDO:0013170
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A autosomal recessive cutis laxa type I that has material basis in homozygous or compound heterozygous mutation in the LTBP4 gene on chromosome 19q13","definition_xrefs":["DOID:0070139"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"inherited cutis laxa","termid":"MONDO:0100237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0006025"],"is_obsolete":false,"name":"cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies","secondary_identifiers":["MESH:C567716","UMLS:C2750804","MEDGEN:442566","Orphanet:221145","icd11.foundation:424903269","GARD:17140","PMID:19836010","OMIM:613177"],"synonyms":[{"name":"ARCL1C","type":"exact"},{"name":"Urban-Rifkin-Davis syndrome","type":"exact"},{"name":"autosomal recessive cutis laxa type 1C","type":"exact"},{"name":"autosomal recessive cutis laxa type IC","type":"related"},{"name":"cutis laxa with Severe pulmonary, gastrointestinal, and urinary abnormalities","type":"related"},{"name":"cutis laxa, autosomal recessive, type 1C","type":"related"},{"name":"cutis laxa, autosomal recessive, type IC","type":"related"}],"termid":"MONDO:0013170","xrefs":{"Monarch":{"xref_id":"0013170"}}}


id: PBO:0109647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taxilin gamma Y-linked (pseudogene)","termid":"PBO:0109647"}


id: MONDO:0011767
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the WHRN gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 31","secondary_identifiers":["MESH:C564629","OMIM:607084","DOID:0110490","UMLS:C1846839","GARD:22602","MEDGEN:339621"],"synonyms":[{"name":"DFNB31","type":"narrow"},{"name":"WHRN autosomal recessive nonsyndromic deafness","type":"narrow"},{"name":"autosomal recessive deafness 31","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 31","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness caused by mutation in WHRN","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 31","type":"narrow"},{"name":"autosomal recessive nonsyndromic hearing loss 31","type":"exact"},{"name":"deafness, autosomal recessive 31","type":"narrow"},{"name":"deafness, autosomal recessive type 31","type":"narrow"},{"name":"whirler, mouse, homolog of","type":"related"}],"termid":"MONDO:0011767","xrefs":{"Monarch":{"xref_id":"0011767"}}}


id: PBO:0003575
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"karyopherin Kap109","termid":"PBO:0003575"}


id: PBO:0079788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP glucuronosyltransferase family 1 member A9","termid":"PBO:0079788"}


id: MONDO:0017410
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Porencephaly is characterized by a circumscribed intracerebral cavity of variable size that may be bordered by abnormal polymicrogyric gray matter. In extreme cases, this cavity may result in a communication between the pial surface and the ventricle; this is termed schizencephaly.","definition_xrefs":["Orphanet:2940"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete cerebral malformation with epilepsy (obsolete MONDO:0015655)","termid":"MONDO:0015655"},{"relation_name":"is_a","term_name":"encephaloclastic disorder","termid":"MONDO:0017103"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"porencephaly","secondary_identifiers":["MEDGEN:901502","NANDO:1201074","GARD:7430","HP:0002132","icd11.foundation:137059367","UMLS:C4082173","MESH:D065708","DOID:0060263","MedDRA:10036172"],"termid":"MONDO:0017410","xrefs":{"Monarch":{"xref_id":"0017410"}}}


id: PBO:0073072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syndecan binding protein pseudogene 1","termid":"PBO:0073072"}


id: GO:0080081
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside.","definition_xrefs":["PMID:15604686"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-glucosidase activity","termid":"GO:0008422"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016798","GO:0003674","GO:0016787","GO:0003824"],"is_obsolete":false,"name":"4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity","termid":"GO:0080081"}


id: FYPO:0000238
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a cell fails to resume growth after several days in G0 phase. The inviable cells show some features characteristic of apoptosis, including loss of DNA.","definition_xrefs":["PomBase:mah","PMID:19197239"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable cell","termid":"FYPO:0000049"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000004"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000004"],"is_obsolete":false,"name":"inviable cell upon G0 to G1 transition","synonyms":[{"name":"abolished mitotic competence upon G0 to G1 transition","type":"related"},{"name":"die in G0 with an apoptotic-like phenotype","type":"related"},{"name":"inviable cell upon exit from cell quiescence","type":"exact"},{"name":"inviable cell upon exit from quiescence","type":"exact"},{"name":"lethal in cell upon G0 to G1 transition","type":"exact"}],"termid":"FYPO:0000238"}


id: GO:0016889
data:
  {"annotated_genes":["SJAG_03675","SJAG_05237","SJAG_00623","SJAG_01044","SJAG_02708","SJAG_04752"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74130],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048257"},{"annotations":[100931,59609,78948,74125,78322,94496],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008821"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA endonuclease activity","termid":"GO:0004520"},{"relation_name":"is_a","term_name":"endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters","termid":"GO:0016894"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00623":null,"SJAG_01044":null,"SJAG_02708":null,"SJAG_03675":null,"SJAG_04752":null,"SJAG_05237":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0140097","GO:0003674","GO:0016788","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"DNA endonuclease activity, producing 3'-phosphomonoesters","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["EC:3.1.22.-"],"synonyms":[{"name":"endodeoxyribonuclease activity, producing 3'-phosphomonoesters","type":"exact"},{"name":"endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters","type":"exact"}],"termid":"GO:0016889","terms_by_termid":{"GO:0008821":null,"GO:0048257":null}}


id: MONDO:1011870
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polioencephalomyelopathy, non-human animal","secondary_identifiers":["OMIA:001280"],"termid":"MONDO:1011870","xrefs":{"Monarch":{"xref_id":"1011870"}}}


id: PBO:0051979
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"jade family PHD finger 2","termid":"PBO:0051979"}


id: GO:0043650
data:
  {"annotated_genes":["SJAG_04054","SJAG_02225","SJAG_02408","SJAG_03266","SJAG_03275","SJAG_00518","SJAG_00714","SJAG_00529","SJAG_00337","SJAG_00224","SJAG_04145","SJAG_03580","SJAG_01126","SJAG_03306","SJAG_03485","SJAG_00815","SJAG_04156","SJAG_00106"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[112159,108099],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009257"},{"annotations":[77394,111559],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006532"},{"annotations":[89595,101010,94348,90863,113834],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009423"},{"annotations":[68140],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006761"},{"annotations":[108100,112160,104546,57114,68745,105843,60606],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046656"},{"annotations":[59567,117478,110983],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0097054"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dicarboxylic acid metabolic process","termid":"GO:0043648"},{"relation_name":"is_a","term_name":"carboxylic acid biosynthetic process","termid":"GO:0046394"}],"gene_count":18,"genes_by_uniquename":{"SJAG_00106":null,"SJAG_00224":null,"SJAG_00337":null,"SJAG_00518":null,"SJAG_00529":null,"SJAG_00714":null,"SJAG_00815":null,"SJAG_01126":null,"SJAG_02225":null,"SJAG_02408":null,"SJAG_03266":null,"SJAG_03275":null,"SJAG_03306":null,"SJAG_03485":null,"SJAG_03580":null,"SJAG_04054":null,"SJAG_04145":null,"SJAG_04156":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"dicarboxylic acid biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000043":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"dicarboxylate biosynthesis","type":"exact"},{"name":"dicarboxylate biosynthetic process","type":"exact"},{"name":"dicarboxylic acid anabolism","type":"exact"},{"name":"dicarboxylic acid biosynthesis","type":"exact"},{"name":"dicarboxylic acid formation","type":"exact"},{"name":"dicarboxylic acid synthesis","type":"exact"}],"termid":"GO:0043650","terms_by_termid":{"GO:0006532":null,"GO:0006761":null,"GO:0009257":null,"GO:0009423":null,"GO:0046656":null,"GO:0097054":null}}


id: MONDO:0000893
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare morphologic variant of bronchiolo-alveolar lung carcinoma characterized by the presence of both mucin and non-mucin producing cells.","definition_xrefs":["NCIT:C7270"],"direct_ancestors":[{"relation_name":"is_a","term_name":"minimally invasive lung adenocarcinoma","termid":"MONDO:0004991"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"mixed mucinous and nonmucinous bronchioloalveolar adenocarcinoma","secondary_identifiers":["MEDGEN:220410","ICDO:8254/3","UMLS:C1266036","DOID:0080184"],"synonyms":[{"name":"indeterminate bronchioloalveolar carcinoma","type":"exact"},{"name":"mixed mucinous and non-mucinous bronchioloalveolar adenocarcinoma","type":"exact"},{"name":"mixed mucinous and non-mucinous bronchioloalveolar carcinoma","type":"exact"},{"name":"mixed mucinous and non-mucinous bronchioloalveolar lung carcinoma","type":"exact"},{"name":"mixed mucinous and non-mucinous bronchoalveolar lung carcinoma","type":"exact"}],"termid":"MONDO:0000893","xrefs":{"Monarch":{"xref_id":"0000893"}}}


id: GO:1904212
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of iodide transmembrane transport.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:20392814"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of inorganic anion transmembrane transport","termid":"GO:1903795"},{"relation_name":"is_a","term_name":"regulation of monoatomic anion transmembrane transport","termid":"GO:1903959"},{"relation_name":"is_a","term_name":"regulation of iodide transport","termid":"GO:1904201"},{"relation_name":"regulates","term_name":"iodide transmembrane transport","termid":"GO:1904200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"regulation of iodide transmembrane transport","termid":"GO:1904212"}


id: PBO:0054968
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2382","termid":"PBO:0054968"}


id: PR:Q7Z992
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sst6 gene.","definition_xrefs":["UniProtKB:Q7Z992","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ESCRT-I complex subunit vps23 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC11H11.01","synonyms":[{"name":"Spom972h-sst6","type":"exact"},{"name":"suppressor of ste12 deletion protein 6 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q7Z992"}


id: PBO:0017887
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AAA family ATPase kink, Knk1","termid":"PBO:0017887"}


id: PBO:0047904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, folic acid type, rare, fra(8)(q22.3)","termid":"PBO:0047904"}


id: CHEBI:17345
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GMP","termid":"CHEBI:17345"}


id: PBO:0082813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Conserved E2-like conjugating enzyme; mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy","termid":"PBO:0082813"}


id: PBO:0068150
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 457","termid":"PBO:0068150"}


id: MONDO:0013766
data:
  {"annotated_genes":["SJAG_00321"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86418],"is_not":false,"summary":null,"term":"MONDO:0013766"}]},"cv_name":"mondo","definition":"A rare, hereditary, immune deficiency with skin involvement characterized by early-onset cold urticaria after generalized exposure to cold air or evaporative cooling and not after contact with cold objects. Additional immunologic abnormalities are often present - antibody deficiency, recurrent infections, autoimmune disease and symptomatic allergic disease.","definition_xrefs":["Orphanet:300359"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"urticaria","termid":"MONDO:0005492"},{"relation_name":"is_a","term_name":"familial cold autoinflammatory syndrome","termid":"MONDO:0018768"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00321":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"familial cold autoinflammatory syndrome 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:17369","MEDGEN:482544","OMIM:614468","UMLS:C3280914","NANDO:2200455","DOID:0090064"],"synonyms":[{"name":"FACU","type":"exact"},{"name":"FCAS3","type":"related"},{"name":"PLAID","type":"exact"},{"name":"PLCG2 familial cold autoinflammatory syndrome","type":"exact"},{"name":"PLCG2-associated antibody deficiency and immune dysregulation","type":"related"},{"name":"antibody deficiency and immune dysregulation, PLCG2-associated","type":"related"},{"name":"familial atypical cold urticaria","type":"exact"},{"name":"familial cold autoinflammatory syndrome 3","type":"exact"},{"name":"familial cold autoinflammatory syndrome caused by mutation in PLCG2","type":"exact"},{"name":"familial cold autoinflammatory syndrome type 3","type":"exact"},{"name":"familial cold urticaria with common variable immunodeficiency","type":"exact"},{"name":"plaid","type":"exact"}],"termid":"MONDO:0013766","terms_by_termid":{"MONDO:0013766":null},"xrefs":{"Monarch":{"xref_id":"0013766"}}}


id: FYPO:0005414
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of protein measured in a cell during the second meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein level during meiosis","termid":"FYPO:0003611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0006551","FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"increased protein level during meiosis II","synonyms":[{"name":"increased protein accumulation during meiosis II","type":"related"},{"name":"increased protein level during second meiotic nuclear division","type":"exact"}],"termid":"FYPO:0005414"}


id: PBO:0065638
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase non-receptor type 13","termid":"PBO:0065638"}


id: SO:0000554
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000554 assortment_derived_deficiency_plus_duplication (obsolete SO:0000554)","termid":"SO:0000554"}


id: MONDO:0005044
data:
  {"annotated_genes":["SJAG_02977","SJAG_03081"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87083],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007781"},{"annotations":[86682],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013458"}]},"cv_name":"mondo","definition":"Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.","definition_xrefs":["MESH:D006973"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arterial disorder","termid":"MONDO:0000473"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02977":null,"SJAG_03081":null},"genotype_count":0,"is_obsolete":false,"name":"hypertensive disorder","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0020538","ICD9:401-405.99","ICD10CM:I10-I16","ICD9:997.91","NCIT:C3117","HP:0000822","MEDGEN:6969","DOID:10763","EFO:0000537","ICD10CM:I15","SCTID:38341003"],"synonyms":[{"name":"HTN","type":"broad"},{"name":"blood pressure, high","type":"exact"},{"name":"blood pressure, increased","type":"exact"},{"name":"high blood pressure","type":"exact"},{"name":"hyperpiesia","type":"exact"},{"name":"hypertension","type":"related"},{"name":"hypertensive disease","type":"exact"},{"name":"increased blood pressure","type":"exact"},{"name":"pressure, high blood","type":"exact"},{"name":"vascular hypertensive disorder","type":"exact"}],"termid":"MONDO:0005044","terms_by_termid":{"MONDO:0007781":null,"MONDO:0013458":null},"xrefs":{"Monarch":{"xref_id":"0005044"}}}


id: GO:0085042
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A host-derived membrane surrounding the symbiont arbuscule during symbiosis.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell membrane","termid":"GO:0033644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"periarbuscular membrane","termid":"GO:0085042"}


id: PBO:0034651
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_glycerol_level_during_cellular_response_to_osmotic_stress","termid":"PBO:0034651"}


id: GO:0102529
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: apigenin + S-adenosyl-L-methionine = genkwanin + H+ + S-adenosyl-L-homocysteine.","definition_xrefs":["RHEA:73071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methyltransferase activity","termid":"GO:0008168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0016741","GO:0003824","GO:0003674","GO:0016740"],"is_obsolete":false,"name":"apigenin 7-O-methyltransferase activity","secondary_identifiers":["MetaCyc:RXN-14661"],"termid":"GO:0102529"}


id: GO:0060761
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.","definition_xrefs":["GOC:tb","GOC:BHF","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of response to stimulus","termid":"GO:0048585"},{"relation_name":"is_a","term_name":"regulation of response to cytokine stimulus","termid":"GO:0060759"},{"relation_name":"negatively_regulates","term_name":"response to cytokine","termid":"GO:0034097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of response to cytokine stimulus","termid":"GO:0060761"}


id: GO:0044220
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The host cell cytoplasm situated near, or occurring around, the host nucleus.","definition_xrefs":["GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell cytoplasm part","termid":"GO:0033655"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host cell perinuclear region of cytoplasm","termid":"GO:0044220"}


id: FYPO:0003904
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the plasma membrane is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal subcellular component during vegetative growth","termid":"FYPO:0001313"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal plasma membrane morphology","synonyms":[{"name":"normal plasma membrane morphology during mitotic cell cycle","type":"related"},{"name":"normal plasma membrane morphology during vegetative growth","type":"exact"}],"termid":"FYPO:0003904"}


id: PBO:0082624
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation","termid":"PBO:0082624"}


id: PBO:0041604
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CA15 pseudogene 1","termid":"PBO:0041604"}


id: PBO:0042074
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil domain containing 144A","termid":"PBO:0042074"}


id: PBO:0051923
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ITGB5 antisense RNA 1","termid":"PBO:0051923"}


id: PBO:0027876
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_nucleosome_binding","termid":"PBO:0027876"}


id: PBO:0059914
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND1 pseudogene 37","termid":"PBO:0059914"}


id: PBO:0090295
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RhoGEF for Rho1, Rgf3","termid":"PBO:0090295"}


id: GO:0070762
data:
  {"annotated_genes":["SJAG_03200","SJAG_01834"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[73873,119017],"is_not":false,"summary":null,"term":"GO:0070762"}]},"cv_name":"cellular_component","definition":"A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.","definition_xrefs":["PMID:22419078","GOC:dgf","PMID:18046406","PMID:20947011","PMID:19524430"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"},{"relation_name":"part_of","term_name":"nuclear pore","termid":"GO:0005643"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01834":null,"SJAG_03200":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005643"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005643","GO:0032991","GO:0005634","GO:0005575"],"is_obsolete":false,"name":"nuclear pore transmembrane ring","references_by_uniquename":{"GO_REF:0000033":null,"PMID:21733045":null},"synonyms":[{"name":"NDC1 complex","type":"exact"},{"name":"NDC1 subcomplex","type":"exact"}],"termid":"GO:0070762","terms_by_termid":{"GO:0070762":null}}


id: PATO:0000956
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A fertility quality inhering in a bearer by virtue of the bearer's being incapable of initiating, sustaining, or supporting reproduction.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fertility","termid":"PATO:0000274"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sterile","termid":"PATO:0000956"}


id: GO:0009761
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis.","definition_xrefs":["ISBN:0582015952"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon fixation","termid":"GO:0015977"},{"relation_name":"is_a","term_name":"photosynthesis, dark reaction","termid":"GO:0019685"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"CAM photosynthesis","secondary_identifiers":["Wikipedia:Crassulacean_acid_metabolism"],"termid":"GO:0009761"}


id: PBO:0065372
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"presenilin enhancer, gamma-secretase subunit","termid":"PBO:0065372"}


id: GO:1904876
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.","definition_xrefs":["GOC:TermGenie","GOC:BHF","GO_REF:0000059","GOC:BHF_telomere","GOC:rl","PMID:17389648"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of DNA ligase activity (obsolete GO:1904876)","synonyms":[{"name":"down regulation of DNA ligase activity","type":"exact"},{"name":"down-regulation of DNA ligase activity","type":"exact"},{"name":"downregulation of DNA ligase activity","type":"exact"},{"name":"inhibition of DNA ligase activity","type":"narrow"}],"termid":"GO:1904876"}


id: PBO:0056834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase","termid":"PBO:0056834"}


id: PBO:0040007
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP ribosylation factor like GTPase 15","termid":"PBO:0040007"}


id: PBO:0108548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"clathrin adaptor End4","termid":"PBO:0108548"}


id: FYPO:0008229
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phosphate (Pi). Cells stop growing (and may die) at a concentration of phosphate that allows wild type cells to grow.","direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002683","FYPO:0005447","FYPO:0000003","FYPO:0000139"],"is_obsolete":false,"name":"sensitive to phosphate (Pi)","termid":"FYPO:0008229"}


id: MONDO:0017948
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hereditary cerebral hemorrhage with amyloidosis (HCHWA), Flemish type is a form of HCHWA characterized by an age of onset of 45 years of age, progressive Alzheimer's disease-like dementia and lobar intracerebral hemorrhage in some patients.","definition_xrefs":["Orphanet:324718"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cerebral amyloid angiopathy, APP-related","termid":"MONDO:0011583"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0021179"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0021179"],"is_obsolete":false,"name":"ABetaA21G amyloidosis","secondary_identifiers":["UMLS:C3888307","ICD10EXP:I68.0*","GARD:17492","MEDGEN:854853","ICD10EXP:E85.4+"],"synonyms":[{"name":"ABeta amyloidosis, Flemish type","type":"exact"},{"name":"ABetaA21G-related amyloidosis","type":"exact"},{"name":"HCHWA, Flemish type","type":"exact"},{"name":"cerebral amyloid angiopathy, APP-related, Flemish variant","type":"exact"},{"name":"hereditary cerebral haemorrhage with amyloidosis, Flemish type","type":"exact"},{"name":"hereditary cerebral hemorrhage with amyloidosis, Flemish type","type":"exact"}],"termid":"MONDO:0017948","xrefs":{"Monarch":{"xref_id":"0017948"}}}


id: GO:1902169
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.","definition_xrefs":["GOC:rjd","PMID:23516620","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to catechin","termid":"GO:1902168"},{"relation_name":"is_a","term_name":"cellular response to flavonoid","termid":"GO:1905396"},{"relation_name":"is_a","term_name":"cellular response to phenylpropanoid","termid":"GO:1905546"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to catechin","termid":"GO:1902169"}


id: PATO:0000642
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in a bearer by virtue of the bearer's being merged with another entity.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"structure","termid":"PATO:0000141"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fused with","synonyms":[{"name":"coalesced","type":"related"},{"name":"fused","type":"exact"},{"name":"fused to","type":"exact"},{"name":"joined with","type":"related"},{"name":"merged with","type":"related"}],"termid":"PATO:0000642"}


id: FYPO:0000155
data:
  {"alleles_by_uniquename":{"SJAG_02527:allele-1":{"allele_type":"disruption","description":"RNA sequencing revealed that only the 5' end of the disrupted allele showed low RNA expression and coverage","gene_uniquename":"SJAG_02527","name":"lig4::KanMX6","uniquename":"SJAG_02527:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[119268],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0009111"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype that reflects increased occurrence of flocculation. Flocculation is the non-sexual aggregation of single cells.","definition_xrefs":["GO:0000128","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal biological process","termid":"FYPO:0005447"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02527":null},"genotype_count":1,"genotypes_by_uniquename":{"lig4::KanMX6-RNA_sequencing_revealed_that_only_the_5'_end_of_the_disrupted_allele_showed_low_RNA_expression_and_coverage-disruption-expression-knockdown":{"display_name":"lig4::KanMX6(RNA sequencing revealed that only the 5' end of the disrupted allele showed low RNA expression and coverage)[Knockdown]","display_uniquename":"lig4::KanMX6-RNA_sequencing_revealed_that_only_the_5'_end_of_the_disrupted_allele_showed_low_RNA_expression_and_coverage-disruption-expression-knockdown","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02527:allele-1","expression":"Knockdown"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"increased flocculation","references_by_uniquename":{"PMID:37233261":null},"secondary_identifiers":["FYPO:0000462"],"single_locus_annotated_genes":["SJAG_02527"],"single_locus_genotype_uniquenames":["lig4::KanMX6-RNA_sequencing_revealed_that_only_the_5'_end_of_the_disrupted_allele_showed_low_RNA_expression_and_coverage-disruption-expression-knockdown"],"synonyms":[{"name":"flocculating cells","type":"exact"},{"name":"flocculation: increased","type":"related"},{"name":"increased cell-cell adhesion","type":"broad"}],"termid":"FYPO:0000155","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000081":null,"FYPO:0009111":null}}


id: GO:0007098
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.","definition_xrefs":["ISBN:0815316194"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle process","termid":"GO:0022402"},{"relation_name":"is_a","term_name":"microtubule organizing center organization","termid":"GO:0031023"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007010"},{"rel_name":"part_of","termid":"GO:0000226"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007049","GO:0007010","GO:0008150","GO:0000226"],"is_obsolete":false,"name":"centrosome cycle","secondary_identifiers":["GO:0051297"],"synonyms":[{"name":"centrosome organisation","type":"exact"},{"name":"centrosome organization","type":"exact"},{"name":"centrosome organization and biogenesis","type":"related"}],"termid":"GO:0007098"}


id: MONDO:0005112
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant neoplasm that arises from mesothelial cells in the pleura and shows a diffuse growth pattern. It arises on the parietal and sometimes visceral pleura as multiple small nodules that later become confluent and invade the chest wall adipose tissue and muscle. Asbestos exposure is the main cause for the development of pleural malignant mesothelioma. It usually affects patients over sixty years of age. The latency period is long. Patients usually present with pleural effusion, dyspnea and chest wall pain. Additional signs and symptoms include chills, sweating, weight loss, and weakness. Morphologic variants include epithelioid, desmoplastic, sarcomatoid, and biphasic mesothelioma. The clinical course is usually aggressive.","definition_xrefs":["NCIT:C7376"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pleural mesothelioma","termid":"MONDO:0003308"},{"relation_name":"is_a","term_name":"malignant mesothelioma","termid":"MONDO:0006292"},{"relation_name":"is_a","term_name":"pleural cancer","termid":"MONDO:0006294"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"malignant pleural mesothelioma","secondary_identifiers":["DOID:7474","EFO:0000770","UMLS:C0812413","MEDGEN:208810","SCTID:254645002"],"synonyms":[{"name":"malignant mesothelioma of pleura","type":"exact"},{"name":"malignant mesothelioma of the pleura","type":"exact"},{"name":"malignant pleural mesothelioma","type":"exact"},{"name":"pleura mesothelioma","type":"broad"},{"name":"pleural diffuse malignant mesothelioma","type":"exact"},{"name":"pleural malignant mesothelioma","type":"exact"}],"termid":"MONDO:0005112","xrefs":{"Monarch":{"xref_id":"0005112"}}}


id: PBO:0082309
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Aspartic-type endopeptidase; involved in the cleavage of long-chain polyubiquitinated substrates; role in proteasome-independent, ubiquitin (Ub)-dependent proteolysis and DNA-protein crosslink repair; Ub-shuttle receptor for HO and Ufo1p; DNA damage-inducible v-SNARE binding protein and negative regulator of constitutive exocytosis; possible role in the S-phase checkpoint; UBL-UBA family member containing Ub-like (UBL), helical, Ub-associated (UBA) and retroviral-like proteinase (RVP) domains","termid":"PBO:0082309"}


id: FYPO:0000319
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of spores and germinated spores most of which go on to divide once or twice. Some germinated spores remain septated and do not complete cell division.","definition_xrefs":["PomBase:mah","PomBase:jh"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable mixed population including spores and divided germinated spores (obsolete FYPO:0000319)","synonyms":[{"name":"put cut","type":"related"}],"termid":"FYPO:0000319"}


id: PBO:0088488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein N-terminal amidase Nta1","termid":"PBO:0088488"}


id: PBO:0042673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CEA cell adhesion molecule pseudogene 7","termid":"PBO:0042673"}


id: PBO:0041585
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 22 open reading frame 46, pseudogene","termid":"PBO:0041585"}


id: GO:0003083
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney.","definition_xrefs":["GOC:mtg_cardio","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of renal output by angiotensin","termid":"GO:0002019"},{"relation_name":"is_a","term_name":"positive regulation of systemic arterial blood pressure","termid":"GO:0003084"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of renal output by angiotensin","synonyms":[{"name":"angiotensin mediated negative regulation of renal output","type":"exact"},{"name":"angiotensin-mediated negative regulation of renal output","type":"exact"}],"termid":"GO:0003083"}


id: GO:1902057
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate.","definition_xrefs":["GOC:TermGenie","PMID:20178781"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid metabolic process","termid":"GO:0008202"},{"relation_name":"is_a","term_name":"carboxylic acid metabolic process","termid":"GO:0019752"},{"relation_name":"is_a","term_name":"ketone metabolic process","termid":"GO:0042180"},{"relation_name":"is_a","term_name":"olefinic compound metabolic process","termid":"GO:0120254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629","GO:0044281"],"is_obsolete":false,"name":"(25S)-Delta(4)-dafachronate metabolic process","synonyms":[{"name":"(25S)-Delta(4)-dafachronate metabolism","type":"exact"}],"termid":"GO:1902057"}


id: PBO:0042988
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CHEK2 pseudogene 1","termid":"PBO:0042988"}


id: PBO:0027140
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_RNA_level_during_cellular_response_to_menadione","termid":"PBO:0027140"}


id: GO:0072593
data:
  {"annotated_genes":["SJAG_04403","SJAG_01216","SJAG_04632","SJAG_03303","SJAG_01734","SJAG_00668","SJAG_04399","SJAG_05181","SJAG_04953","SJAG_01199","SJAG_04823","SJAG_03653","SJAG_04788","SJAG_03166","SJAG_02515","SJAG_00141"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117110,104806,99759,94953,108588,118031],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061692"},{"annotations":[104807,108589,75585,70696,94955,99761,70045],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042744"},{"annotations":[74105,99035,92902,68420,89163,88741,58070,64937,60844],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019430"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic process","termid":"GO:0008152"}],"gene_count":16,"genes_by_uniquename":{"SJAG_00141":null,"SJAG_00668":null,"SJAG_01199":null,"SJAG_01216":null,"SJAG_01734":null,"SJAG_02515":null,"SJAG_03166":null,"SJAG_03303":null,"SJAG_03653":null,"SJAG_04399":null,"SJAG_04403":null,"SJAG_04632":null,"SJAG_04788":null,"SJAG_04823":null,"SJAG_04953":null,"SJAG_05181":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"reactive oxygen species metabolic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"ROS metabolic process","type":"exact"},{"name":"reactive oxygen species metabolism","type":"exact"}],"termid":"GO:0072593","terms_by_termid":{"GO:0019430":null,"GO:0042744":null,"GO:0061692":null}}


id: MONDO:0007521
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete egasyn (obsolete MONDO:0007521)","secondary_identifiers":["OMIM:129905"],"synonyms":[{"name":"egasyn","type":"exact"},{"name":"esterase 22","type":"related"}],"termid":"MONDO:0007521","xrefs":{"Monarch":{"xref_id":"0007521"}}}


id: GO:0043778
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate.","definition_xrefs":["MetaCyc:RXN-8768"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular acyltransferase activity","termid":"GO:0016867"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016853"}],"interesting_parent_ids":["GO:0016853","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"cobalt-precorrin-8 methylmutase activity","secondary_identifiers":["EC:5.4.99.60","RHEA:16209"],"synonyms":[{"name":"cobalt-precorrin 8 methylmutase activity","type":"exact"},{"name":"cobalt-precorrin 8X methylmutase activity","type":"exact"},{"name":"cobalt-precorrin-8X methylmutase activity","type":"exact"}],"termid":"GO:0043778"}


id: PBO:0060617
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neutrophil cytosolic factor 2","termid":"PBO:0060617"}


id: MONDO:0007912
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lithium transport","secondary_identifiers":["MEDGEN:331956","UMLS:C1835356","OMIM:152420"],"synonyms":[{"name":"lithium transport","type":"exact"}],"termid":"MONDO:0007912","xrefs":{"Monarch":{"xref_id":"0007912"}}}


id: PBO:0005204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exocyst complex subunit Sec15 (predicted)","termid":"PBO:0005204"}


id: GO:0014064
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.","definition_xrefs":["GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of serotonin secretion","termid":"GO:0014062"},{"relation_name":"is_a","term_name":"positive regulation of monoatomic ion transport","termid":"GO:0043270"},{"relation_name":"is_a","term_name":"positive regulation of secretion by cell","termid":"GO:1903532"},{"relation_name":"positively_regulates","term_name":"serotonin secretion","termid":"GO:0001820"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of serotonin secretion","synonyms":[{"name":"activation of serotonin secretion","type":"narrow"},{"name":"positive regulation of serotonin release","type":"related"},{"name":"stimulation of serotonin secretion","type":"narrow"},{"name":"up regulation of serotonin secretion","type":"exact"},{"name":"up-regulation of serotonin secretion","type":"exact"},{"name":"upregulation of serotonin secretion","type":"exact"}],"termid":"GO:0014064"}


id: PBO:0042174
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cellular communication network factor 4","termid":"PBO:0042174"}


id: PBO:0045386
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dipeptidyl peptidase 8","termid":"PBO:0045386"}


id: MOD:01940
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that crosslinks an asparagine and the following glutamic acid residue with the formation of (2-aminosuccinimidyl)pentanedioic acid and the release of ammonia.","definition_xrefs":["RESID:AA0593#ASN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-(2-aminosuccinimidyl)pentanedioic acid","termid":"MOD:01946"},{"relation_name":"is_a","term_name":"crosslinked L-asparagine residue","termid":"MOD:02042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2-(2-aminosuccinimidyl)pentanedioic acid (Asn)","synonyms":[{"name":"(4S)-4-[(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]-5-oxopentanoic acid","type":"exact"},{"name":"2-(2-aminosuccinimidyl)pentanedioic acid","type":"exact"},{"name":"aspartimide glutamic acid","type":"exact"}],"termid":"MOD:01940"}


id: PBO:0050358
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 pseudogene 61","termid":"PBO:0050358"}


id: GO:0023040
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux.","definition_xrefs":["GOC:mtg_signal"],"gene_count":0,"genotype_count":0,"name":"obsolete signaling via ionic flux (obsolete GO:0023040)","synonyms":[{"name":"signaling via ionic flux","type":"exact"},{"name":"signalling via ionic flux","type":"exact"}],"termid":"GO:0023040"}


id: SO:0001788
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An U-box is a conserved T-rich region upstream of a retroviral polypurine tract that is involved in PPT primer creation during reverse transcription.","definition_xrefs":["PMID:9649446","PMID:10556309","PMID:11577982"],"direct_ancestors":[{"relation_name":"is_a","term_name":"conserved_region","termid":"SO:0000330"},{"relation_name":"part_of","term_name":"LTR_retrotransposon","termid":"SO:0000186"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U_box","synonyms":[{"name":"U-box","type":"exact"}],"termid":"SO:0001788"}


id: FYPO:0001333
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A regulation phenotype that affects the regulation of gene expression in the vegetative growth phase of the life cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression regulation phenotype","termid":"FYPO:0000288"},{"relation_name":"is_a","term_name":"regulation phenotype during vegetative growth","termid":"FYPO:0001334"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"gene expression regulation phenotype during vegetative growth","synonyms":[{"name":"fission yeast gene expression regulation phenotype during vegetative growth","type":"exact"},{"name":"gene expression regulation phenotype during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001333"}


id: PBO:0057026
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR124-2 host gene","termid":"PBO:0057026"}


id: PBO:0073195
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"selectin L","termid":"PBO:0073195"}


id: MONDO:1012508
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Guillain-Barr-like polyradiculoneuropathy, non-human animal","termid":"MONDO:1011895"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Guillain-Barr-like polyradiculoneuropathy, domestic cat","secondary_identifiers":["OMIA:002062-9685"],"termid":"MONDO:1012508","xrefs":{"Monarch":{"xref_id":"1012508"}}}


id: PBO:0086123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","termid":"PBO:0086123"}


id: GO:0019567
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pentose biosynthetic process","termid":"GO:0019322"},{"relation_name":"is_a","term_name":"arabinose metabolic process","termid":"GO:0019566"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0005975"],"is_obsolete":false,"name":"arabinose biosynthetic process","synonyms":[{"name":"arabinose anabolism","type":"exact"},{"name":"arabinose biosynthesis","type":"exact"},{"name":"arabinose formation","type":"exact"},{"name":"arabinose synthesis","type":"exact"}],"termid":"GO:0019567"}


id: PBO:0085464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Predicted tail-anchored plasma membrane protein; contains conserved CYSTM module; related proteins in other organisms may be involved in response to stress; N- and C-terminal fusion proteins localize to the cell periphery; YDR034W-B has a paralog, YBR056W-A, that arose from the whole genome duplication","termid":"PBO:0085464"}


id: SO:0001048
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region located within an inversion site.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"site_specific_recombination_target_region","termid":"SO:0000342"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inversion_site_part","synonyms":[{"name":"inversion site part","type":"exact"}],"termid":"SO:0001048"}


id: GO:2001118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methanopterin-containing compound biosynthetic process","termid":"GO:2001116"},{"relation_name":"is_a","term_name":"tetrahydromethanopterin metabolic process","termid":"GO:2001117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0042559"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0042559"],"is_obsolete":false,"name":"tetrahydromethanopterin biosynthetic process","synonyms":[{"name":"tetrahydromethanopterin biosynthesis","type":"exact"}],"termid":"GO:2001118"}


id: PBO:0081623
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 552","termid":"PBO:0081623"}


id: PBO:0064671
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase A pseudogene 6","termid":"PBO:0064671"}


id: PBO:0066865
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 165","termid":"PBO:0066865"}


id: MONDO:0006419
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A precancerous neoplastic process that affects the small intestine. It is characterized by low or high grade dysplasia of the mucosal epithelium. There is no evidence of invasion.","definition_xrefs":["NCIT:C27462"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small intestine neoplasm","termid":"MONDO:0004251"},{"relation_name":"is_a","term_name":"colorectal neoplasm","termid":"MONDO:0005335"},{"relation_name":"is_a","term_name":"intraepithelial neoplasia","termid":"MONDO:0024474"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"small intestinal intraepithelial neoplasia","secondary_identifiers":["MEDGEN:236822","UMLS:C1335999"],"synonyms":[{"name":"small intestinal dysplasia","type":"exact"},{"name":"small intestinal intraepithelial neoplasia","type":"exact"}],"termid":"MONDO:0006419","xrefs":{"Monarch":{"xref_id":"0006419"}}}


id: GO:0044034
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - which involves more than one organism.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete multi-organism biosynthetic process (obsolete GO:0044034)","synonyms":[{"name":"multi-organism biosynthesis","type":"exact"},{"name":"multi-organismal biosynthesis","type":"exact"},{"name":"multi-organismal biosynthetic process","type":"exact"}],"termid":"GO:0044034"}


id: MONDO:0014622
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete nonepidermolytic palmoplantar keratoderma (obsolete MONDO:0006588)","termid":"MONDO:0006588"},{"relation_name":"is_a","term_name":"focal palmoplantar keratoderma","termid":"MONDO:0017672"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"isolated focal non-epidermolytic palmoplantar keratoderma","secondary_identifiers":["OMIM:616400","MEDGEN:895056","Orphanet:448264","GARD:17781","UMLS:C4225339","DOID:0111711","DOID:0111708"],"synonyms":[{"name":"FNEPPK2","type":"related"},{"name":"palmoplantar keratoderma, nonepidermolytic, focal 2","type":"related"},{"name":"palmoplantar keratoderma, nonepidermolytic, focal type 2","type":"exact"}],"termid":"MONDO:0014622","xrefs":{"Monarch":{"xref_id":"0014622"}}}


id: PBO:0001149
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ammonium transporter Amt2","termid":"PBO:0001149"}


id: GO:0002584
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of antigen processing and presentation","termid":"GO:0002578"},{"relation_name":"is_a","term_name":"regulation of antigen processing and presentation of peptide antigen","termid":"GO:0002583"},{"relation_name":"negatively_regulates","term_name":"antigen processing and presentation of peptide antigen","termid":"GO:0048002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of antigen processing and presentation of peptide antigen","synonyms":[{"name":"down regulation of antigen processing and presentation of peptide antigen","type":"exact"},{"name":"down-regulation of antigen processing and presentation of peptide antigen","type":"exact"},{"name":"downregulation of antigen processing and presentation of peptide antigen","type":"exact"},{"name":"inhibition of antigen processing and presentation of peptide antigen","type":"narrow"},{"name":"negative regulation of peptide antigen processing and presentation","type":"exact"}],"termid":"GO:0002584"}


id: PATO:0001223
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001223 quantitative value (obsolete PATO:0001223)","termid":"PATO:0001223"}


id: PBO:0058416
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4785","termid":"PBO:0058416"}


id: GO:0010934
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["GOC:BHF","GOC:dph","GOC:tb","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid leukocyte cytokine production","termid":"GO:0061082"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"macrophage cytokine production","termid":"GO:0010934"}


id: FYPO:0005442
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation is abnormal at the telomeric regions. The remainder of the sister chromatids may or may not separate normally.","definition_xrefs":["PomBase:mah","PMID:21540296"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic sister chromatid separation","termid":"FYPO:0000670"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000337"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0000337"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0001320"},{"rel_name":"part_of","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"part_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000337","FYPO:0000641","FYPO:0005447","FYPO:0001985","FYPO:0000631","FYPO:0001320"],"is_obsolete":false,"name":"abnormal telomeric DNA separation","synonyms":[{"name":"abnormal DNA separation at telomere","type":"exact"},{"name":"abnormal mitotic sister chromatid separation at telomere","type":"exact"},{"name":"abnormal mitotic telomeric DNA separation","type":"exact"},{"name":"abnormal segregation of telomeric DNA","type":"related"},{"name":"abnormal telomere separation","type":"exact"},{"name":"abnormal telomeric DNA separation during mitosis","type":"exact"},{"name":"abnormal telomeric DNA separation during mitotic cell cycle","type":"related"},{"name":"abnormal telomeric DNA separation during vegetative growth","type":"exact"}],"termid":"FYPO:0005442"}


id: GO:0008795
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.","definition_xrefs":["EC:6.3.1.5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acid-ammonia (or amide) ligase activity","termid":"GO:0016880"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016874"],"is_obsolete":false,"name":"NAD+ synthase activity","secondary_identifiers":["GO:0016965","MetaCyc:NAD-SYNTH-NH3-RXN","GO:0008749","RHEA:21188"],"synonyms":[{"name":"NAD synthase (AMP-forming)","type":"exact"},{"name":"NAD synthase activity","type":"exact"},{"name":"NAD synthetase activity","type":"related"},{"name":"NAD(+) synthetase activity","type":"related"},{"name":"NAD+ synthetase activity","type":"related"},{"name":"deamido-NAD+:ammonia ligase (AMP-forming)","type":"related"},{"name":"diphosphopyridine nucleotide synthetase activity","type":"related"},{"name":"nicotinamide adenine dinucleotide synthetase activity","type":"related"}],"termid":"GO:0008795"}


id: MOD:00278
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-glutamine residue to 2-methyl-L-glutamine.","definition_xrefs":["RESID:AA0273","PubMed:11875433","PubMed:9367957","PubMed:10660523"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C-methylated residue","termid":"MOD:00656"},{"relation_name":"is_a","term_name":"monomethylated L-glutamine","termid":"MOD:00722"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"2-methyl-L-glutamine","synonyms":[{"name":"(S)-2-amino-2-methylpentanediamic acid","type":"exact"},{"name":"2-methyl-L-glutamine","type":"exact"},{"name":"2-methylated L-glutamine","type":"exact"},{"name":"2-methylglutamine","type":"exact"},{"name":"C2MeGln","type":"exact"},{"name":"MOD_RES 2-methylglutamine","type":"exact"},{"name":"Methyl","type":"related"},{"name":"Methylation","type":"related"},{"name":"alpha-methylglutamine","type":"exact"}],"termid":"MOD:00278"}


id: GO:0004904
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.","definition_xrefs":["GOC:signaling","GOC:ai","PMID:9607096"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine receptor activity","termid":"GO:0004896"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"interferon receptor activity","synonyms":[{"name":"IFN receptor activity","type":"exact"}],"termid":"GO:0004904"}


id: GO:0042704
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovulation cycle process","termid":"GO:0022602"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"uterine wall breakdown","termid":"GO:0042704"}


id: PBO:0041205
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Burkitt lymphoma variant rearranging region 1","termid":"PBO:0041205"}


id: GO:0033210
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.","definition_xrefs":["GOC:yaf","GOC:mah","GOC:signaling"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine-mediated signaling pathway","termid":"GO:0019221"},{"relation_name":"part_of","term_name":"cellular response to leptin stimulus","termid":"GO:0044320"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"leptin-mediated signaling pathway","synonyms":[{"name":"adipocytokine signaling pathway","type":"related"},{"name":"leptin-mediated signalling pathway","type":"exact"}],"termid":"GO:0033210"}


id: PBO:0051761
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"importin 7","termid":"PBO:0051761"}


id: PBO:0091941
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fatty-acid amide hydrolase","termid":"PBO:0091941"}


id: PBO:0110042
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"regulator of DNA class I crossover intermediates 1","termid":"PBO:0110042"}


id: PBO:0062951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PABIR family member 2","termid":"PBO:0062951"}


id: PBO:0054056
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1398","termid":"PBO:0054056"}


id: PBO:0038944
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alcohol dehydrogenase iron containing 1","termid":"PBO:0038944"}


id: MONDO:0003000
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A unique group of rare tumors of the central nervous system that affect mainly children and adolescents. Their morphologic and biologic profile corresponds to that of homologous germ cell tumors that arise in the gonads and in other extragonadal sites. Representative examples include: germinoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma.","definition_xrefs":["NCIT:C5461"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system neoplasm","termid":"MONDO:0006130"},{"relation_name":"is_a","term_name":"extragonadal germ cell tumor","termid":"MONDO:0018201"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"central nervous system germ cell tumor","secondary_identifiers":["DOID:4439","UMLS:C1332880","MEDGEN:232040"],"synonyms":[{"name":"CNS germ cell neoplasm","type":"exact"},{"name":"CNS germ cell tumor","type":"exact"},{"name":"CNS germ cell tumour","type":"exact"},{"name":"central nervous system germ cell neoplasm","type":"exact"},{"name":"central nervous system germ cell tumor","type":"exact"},{"name":"central nervous system rare germ cell tumor","type":"exact"},{"name":"central nervous system rare germ cell tumour","type":"exact"},{"name":"germ cell neoplasm of CNS","type":"exact"},{"name":"germ cell neoplasm of central nervous system","type":"exact"},{"name":"germ cell neoplasm of the CNS","type":"exact"},{"name":"germ cell neoplasm of the central nervous system","type":"exact"},{"name":"germ cell tumor of CNS","type":"exact"},{"name":"germ cell tumor of central nervous system","type":"exact"},{"name":"germ cell tumor of the CNS","type":"exact"},{"name":"germ cell tumor of the central nervous system","type":"exact"},{"name":"germ cell tumour of CNS","type":"exact"},{"name":"germ cell tumour of central nervous system","type":"exact"},{"name":"germ cell tumour of the CNS","type":"exact"},{"name":"germ cell tumour of the central nervous system","type":"exact"}],"termid":"MONDO:0003000","xrefs":{"Monarch":{"xref_id":"0003000"}}}


id: GO:2001251
data:
  {"annotated_genes":["SJAG_00883","SJAG_02451","SJAG_01330","SJAG_04699","SJAG_04999","SJAG_01297","SJAG_01082","SJAG_03681","SJAG_01825","SJAG_04638","SJAG_03353","SJAG_05978","SJAG_04884","SJAG_04259","SJAG_00369","SJAG_00823","SJAG_03591","SJAG_02169","SJAG_02336","SJAG_01679","SJAG_04126","SJAG_00460","SJAG_01716","SJAG_01837","SJAG_03126"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[111706,99350,115643,113524,106987,90486,108006,103647,114011],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1902426"},{"annotations":[99194,114244,109656,115298,106077,101551],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007094"},{"annotations":[117690],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905560"},{"annotations":[103031],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000816"},{"annotations":[93960],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0140499"},{"annotations":[106018,91504,106336,107158,115080,106114],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045875"},{"annotations":[116417],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:0090267"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of organelle organization","termid":"GO:0010639"},{"relation_name":"is_a","term_name":"regulation of chromosome organization","termid":"GO:0033044"},{"relation_name":"negatively_regulates","term_name":"chromosome organization","termid":"GO:0051276"}],"gene_count":25,"genes_by_uniquename":{"SJAG_00369":null,"SJAG_00460":null,"SJAG_00823":null,"SJAG_00883":null,"SJAG_01082":null,"SJAG_01297":null,"SJAG_01330":null,"SJAG_01679":null,"SJAG_01716":null,"SJAG_01825":null,"SJAG_01837":null,"SJAG_02169":null,"SJAG_02336":null,"SJAG_02451":null,"SJAG_03126":null,"SJAG_03353":null,"SJAG_03591":null,"SJAG_03681":null,"SJAG_04126":null,"SJAG_04259":null,"SJAG_04638":null,"SJAG_04699":null,"SJAG_04884":null,"SJAG_04999":null,"SJAG_05978":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of chromosome organization","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"negative regulation of chromosome organisation","type":"exact"},{"name":"negative regulation of chromosome organization and biogenesis","type":"related"},{"name":"negative regulation of maintenance of genome integrity","type":"related"},{"name":"negative regulation of nuclear genome maintenance","type":"related"}],"termid":"GO:2001251","terms_by_termid":{"GO:0007094":null,"GO:0045875":null,"GO:0090267":null,"GO:0140499":null,"GO:1902426":null,"GO:1905560":null,"GO:2000816":null}}


id: FYPO:0006321
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is decreased.","definition_xrefs":["PMID:29215009","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to chromatin during vegetative growth","termid":"FYPO:0000452"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0000138","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased protein localization to chromatin at stalled replication fork","synonyms":[{"name":"decreased protein localisation to chromatin at stalled replication fork during vegetative growth","type":"exact"},{"name":"decreased protein localization to chromatin at stalled replication fork during mitotic cell cycle","type":"related"},{"name":"reduced protein localization to chromatin at stalled replication fork during vegetative growth","type":"exact"}],"termid":"FYPO:0006321"}


id: MONDO:0100540
data:
  {"annotated_genes":["SJAG_02730"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86427],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013770"},{"annotations":[86426],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013769"}]},"cv_name":"mondo","definition":"A congenital heart disease that is present at birth. Representative examples include atrial septal defect 9, conotruncal heart malformations, tetralogy of Fallot, ventricular septal defect, atrioventricular septal defect, bicuspid aortic valve, transposition of the great arteries, persistent truncus arteriosus, congenital heart disease with pancreatic agenesis, and congenital heart disease with neonatal diabetes.","definition_xrefs":["PMID:29653232","PMID:23020118","PMID:35595280","PMID:25937001","PMID:28049534","PMID:31301121","PMID:19666519"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital heart disease","termid":"MONDO:0005453"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02730":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"GATA6-related congenital heart disease with or without pancreatic agenesis or neonatal diabetes","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"GATA6 related congenital heart disease with or without pancreatic agenesis or neonatal diabetes","type":"exact"}],"termid":"MONDO:0100540","terms_by_termid":{"MONDO:0013769":null,"MONDO:0013770":null},"xrefs":{"Monarch":{"xref_id":"0100540"}}}


id: PBO:0051098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin mu DNA binding protein 2","termid":"PBO:0051098"}


id: PBO:0057245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 449b","termid":"PBO:0057245"}


id: GO:0034373
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.","definition_xrefs":["GOC:BHF","GOC:expert_pt","GOC:mah","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triglyceride-rich lipoprotein particle remodeling","termid":"GO:0034370"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"intermediate-density lipoprotein particle remodeling","synonyms":[{"name":"IDL remodeling","type":"exact"},{"name":"IDL remodelling","type":"exact"},{"name":"intermediate-density lipoprotein particle formation","type":"related"},{"name":"intermediate-density lipoprotein particle remodelling","type":"exact"}],"termid":"GO:0034373"}


id: PBO:0046187
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"engulfment and cell motility 2","termid":"PBO:0046187"}


id: PBO:0031671
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_secretion","termid":"PBO:0031671"}


id: PBO:0077183
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"toll like receptor 7","termid":"PBO:0077183"}


id: PBO:0076280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptonemal complex protein 3","termid":"PBO:0076280"}


id: GO:0102481
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate + H+.","definition_xrefs":["RHEA:25836","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances","termid":"GO:0016823"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity","secondary_identifiers":["EC:3.7.1.22","MetaCyc:RXN-14149"],"termid":"GO:0102481"}


id: GO:2000193
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of fatty acid transport.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of lipid transport","termid":"GO:0032370"},{"relation_name":"is_a","term_name":"positive regulation of organic acid transport","termid":"GO:0032892"},{"relation_name":"is_a","term_name":"regulation of fatty acid transport","termid":"GO:2000191"},{"relation_name":"positively_regulates","term_name":"fatty acid transport","termid":"GO:0015908"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of fatty acid transport","termid":"GO:2000193"}


id: MONDO:0007269
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase.","definition_xrefs":["Orphanet:300751"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"familial isolated dilated cardiomyopathy","termid":"MONDO:0700335"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"dilated cardiomyopathy 1A","secondary_identifiers":["OMIM:115200","UMLS:C1449563","SCTID:766883006","MEDGEN:258500","DOID:0110425","GARD:18615"],"synonyms":[{"name":"CDCD1","type":"exact"},{"name":"LMNA familial isolated dilated cardiomyopathy","type":"exact"},{"name":"cardiomyopathy dilated with conduction defect type 1","type":"exact"},{"name":"cardiomyopathy, congestive","type":"related"},{"name":"cardiomyopathy, dilated, 1A","type":"related"},{"name":"cardiomyopathy, dilated, type 1A","type":"exact"},{"name":"cardiomyopathy, dilated, with conduction defect 1","type":"related"},{"name":"cardiomyopathy, familial idiopathic","type":"related"},{"name":"cardiomyopathy, idiopathic dilated","type":"related"},{"name":"dilated cardiomyopathy 1A","type":"exact"},{"name":"dilated cardiomyopathy type 1A","type":"exact"},{"name":"dilated cardiomyopathy with conduction defect 1","type":"exact"},{"name":"familial dilated cardiomyopathy with conduction defect due to LMNA mutation","type":"exact"},{"name":"familial isolated dilated cardiomyopathy caused by mutation in LMNA","type":"exact"}],"termid":"MONDO:0007269","xrefs":{"Monarch":{"xref_id":"0007269"}}}


id: PBO:0082950
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic nucleoporin required for polyadenylated mRNA export; contains a nuclear export signal; when bound to inositol hexakisphosphate (IP6), functions as an activator for the Dbp5p ATPase activity at the nuclear pore complex during mRNA export; mediates translation initiation; required for efficient translation termination","termid":"PBO:0082950"}


id: PBO:0040703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCL2L2-PABPN1 readthrough","termid":"PBO:0040703"}


id: PBO:0028531
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-explosive_cytokinetic_cell_separation_resulting_in_vegetative_cell_lysis","termid":"PBO:0028531"}


id: PBO:0071510
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L34 pseudogene 13","termid":"PBO:0071510"}


id: PBO:0039466
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 13C","termid":"PBO:0039466"}


id: PBO:0062595
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 10 subfamily J member 5","termid":"PBO:0062595"}


id: SO:0000573
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A region that can be transcribed into a ribosomal RNA (rRNA).","direct_ancestors":[{"relation_name":"is_a","term_name":"non_protein_coding","termid":"SO:0000011"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rRNA_encoding","synonyms":[{"name":"rRNA encoding","type":"exact"}],"termid":"SO:0000573"}


id: MONDO:0001852
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-Hodgkin or Hodgkin lymphoma that arises from the small intestine.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small intestine cancer","termid":"MONDO:0000956"},{"relation_name":"is_a","term_name":"gastrointestinal lymphoma","termid":"MONDO:0004699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335","MONDO:0005570"],"is_obsolete":false,"name":"small intestine lymphoma","secondary_identifiers":["DOID:13996","ICD9:202.80","NCIT:C4007","SCTID:449074003","UMLS:C0278805","MEDGEN:82986"],"synonyms":[{"name":"lymphoma of small bowel","type":"exact"},{"name":"lymphoma of small intestine","type":"exact"},{"name":"lymphoma of the small bowel","type":"exact"},{"name":"lymphoma of the small intestine","type":"exact"},{"name":"primary small intestinal lymphoma","type":"exact"},{"name":"small bowel lymphoma","type":"exact"},{"name":"small intestinal lymphoma","type":"exact"},{"name":"small intestine lymphoma","type":"exact"}],"termid":"MONDO:0001852","xrefs":{"Monarch":{"xref_id":"0001852"}}}


id: MONDO:0043343
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Interposition of a portion of the colon (e.g., sigmoid colon) between the liver and the diaphragm. It is associated with abdominal pain, vomiting, constipation, anorexia and volvulus. Chilaiditi anomaly refers to asymptomatic interposition.","definition_xrefs":["MESH:D059269"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colonic disorder","termid":"MONDO:0003409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"Chilaiditi syndrome","secondary_identifiers":["UMLS:C0267494","SCTID:14911005","MEDGEN:452355"],"synonyms":[{"name":"Chilaiditi anomaly","type":"related"},{"name":"Chilaiditi's anomaly","type":"related"},{"name":"Chilaiditi's syndrome","type":"related"},{"name":"Chilaiditis anomaly","type":"related"},{"name":"Chilaiditis syndrome","type":"related"},{"name":"anomaly, Chilaiditi","type":"related"},{"name":"anomaly, Chilaiditi's","type":"related"},{"name":"chilaiditi's syndrome","type":"related"},{"name":"hepatodiaphragmatic colonic interposition","type":"related"},{"name":"subphrenic interposition syndrome","type":"exact"},{"name":"syndrome, Chilaiditi","type":"related"},{"name":"syndrome, Chilaiditi's","type":"related"}],"termid":"MONDO:0043343","xrefs":{"Monarch":{"xref_id":"0043343"}}}


id: GO:0033133
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of hexokinase activity","termid":"GO:1903301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of glucokinase activity","synonyms":[{"name":"glucokinase activator","type":"narrow"},{"name":"stimulation of glucokinase activity","type":"narrow"},{"name":"up regulation of glucokinase activity","type":"exact"},{"name":"up-regulation of glucokinase activity","type":"exact"},{"name":"upregulation of glucokinase activity","type":"exact"}],"termid":"GO:0033133"}


id: MONDO:0859246
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"leukodystrophy","termid":"MONDO:0019046"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"leukodystrophy, childhood-onset, remitting","secondary_identifiers":["MEDGEN:1804145","OMIM:619864","UMLS:C5676979"],"termid":"MONDO:0859246","xrefs":{"Monarch":{"xref_id":"0859246"}}}


id: GO:0007490
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment.","definition_xrefs":["PMID:16451739","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-embryonic animal morphogenesis","termid":"GO:0009886"},{"relation_name":"part_of","term_name":"histoblast morphogenesis","termid":"GO:0007488"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tergite morphogenesis","termid":"GO:0007490"}


id: MOD:00885
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that crosslinks two residues by formation of an ester bond.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"crosslinked residues","termid":"MOD:00033"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ester crosslinked residues","termid":"MOD:00885"}


id: GO:0060785
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of apoptotic process","termid":"GO:0042981"},{"relation_name":"part_of","term_name":"homeostasis of number of cells within a tissue","termid":"GO:0048873"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of apoptosis involved in tissue homeostasis","termid":"GO:0060785"}


id: PBO:0088801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab GAP","termid":"PBO:0088801"}


id: FYPO:0007481
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an increase in the transcription of one or more target genes that would normally occur when cells are subjected to a stress in the presence of a specific small molecule occurs to a lower extent than normal under the same circumstances.","definition_xrefs":["PomBase:mah","PMID:31932483"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal regulation of transcription during vegetative growth","termid":"FYPO:0004527"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0006551","FYPO:0001320"],"is_obsolete":false,"name":"attenuated increase in transcription during cellular response to stress in presence of small molecule","synonyms":[{"name":"attenuated increase in transcription during cellular response to stress in presence of small molecule during mitotic cell cycle","type":"related"},{"name":"attenuated increase in transcription during cellular response to stress in presence of small molecule during vegetative growth","type":"exact"}],"termid":"FYPO:0007481"}


id: SO:0000740
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"DNA belonging to the genome of a plastid such as a chloroplast.","direct_ancestors":[{"relation_name":"is_a","term_name":"organelle_sequence","termid":"SO:0000736"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plastid_sequence","synonyms":[{"name":"plastid sequence","type":"exact"}],"termid":"SO:0000740"}


id: GO:0009102
data:
  {"annotated_genes":["SJAG_01935","SJAG_00673"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76008,79177],"is_not":false,"summary":null,"term":"GO:0009102"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biotin metabolic process","termid":"GO:0006768"},{"relation_name":"is_a","term_name":"water-soluble vitamin biosynthetic process","termid":"GO:0042364"},{"relation_name":"is_a","term_name":"amide biosynthetic process","termid":"GO:0043604"},{"relation_name":"is_a","term_name":"sulfur compound biosynthetic process","termid":"GO:0044272"},{"relation_name":"is_a","term_name":"monocarboxylic acid biosynthetic process","termid":"GO:0072330"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00673":null,"SJAG_01935":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006766"}],"interesting_parent_ids":["GO:0006790","GO:0008150","GO:0044281","GO:0006766"],"is_obsolete":false,"name":"biotin biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:BIOTIN-SYN"],"synonyms":[{"name":"biotin anabolism","type":"exact"},{"name":"biotin biosynthesis","type":"exact"},{"name":"biotin formation","type":"exact"},{"name":"biotin synthesis","type":"exact"},{"name":"vitamin B7 biosynthesis","type":"exact"},{"name":"vitamin B7 biosynthetic process","type":"exact"},{"name":"vitamin H biosynthesis","type":"exact"},{"name":"vitamin H biosynthetic process","type":"exact"}],"termid":"GO:0009102","terms_by_termid":{"GO:0009102":null}}


id: FYPO:0004363
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell differs from normal (i.e. is higher or lower than observed in wild-type cells during vegetative growth).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered RNA level during vegetative growth","termid":"FYPO:0001326"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0006551","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"altered level of stress responsive gene mRNA during vegetative growth","synonyms":[{"name":"abnormal level of stress responsive gene mRNA during vegetative growth","type":"exact"},{"name":"altered level of cellular response to stress responsive gene mRNA","type":"exact"},{"name":"altered level of stress responsive gene RNA during vegetative growth","type":"exact"},{"name":"altered level of stress responsive gene mRNA during mitotic cell cycle","type":"related"},{"name":"altered level of stress responsive gene transcripts during vegetative growth","type":"exact"},{"name":"altered mRNA level of stress responsive genes during vegetative growth","type":"exact"},{"name":"altered stress responsive gene mRNA accumulation during vegetative growth","type":"related"}],"termid":"FYPO:0004363"}


id: PBO:0091330
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by A. fumigatus PzhA","termid":"PBO:0091330"}


id: PBO:0004280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNARE Sec22 (predicted)","termid":"PBO:0004280"}


id: PBO:0077732
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tensin 1","termid":"PBO:0077732"}


id: MONDO:0015439
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ring chromosome 4 syndrome is an autosomal anomaly characterized by variable clinical features, most commonly including significant intrauterine and postnatal growth retardation, developmental delay, intellectual disability, microcephaly, and dysmorphic facial features. Some less frequent features are cleft lip and/or cleft palate, congenital cardiovascular, gastrointestinal and genitourinary system anomalies.","definition_xrefs":["Orphanet:1447"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome 4 disorder","termid":"MONDO:0700011"},{"relation_name":"is_a","term_name":"ring chromosome disorder","termid":"MONDO:0700091"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring chromosome 4","secondary_identifiers":["MESH:C537636","MEDGEN:75571","GARD:1339","NORD:1671","SCTID:81678004","NCIT:C121983","UMLS:C0265407"],"synonyms":[{"name":"R4","type":"related"},{"name":"Ring 4","type":"related"},{"name":"Ring chromosome 4 syndrome","type":"related"},{"name":"Ring chromosome type 4","type":"exact"},{"name":"chromosome 4 ring","type":"related"},{"name":"r(4) syndrome","type":"exact"},{"name":"rose cluster 4","type":"exact"},{"name":"syndrome r(4)","type":"exact"}],"termid":"MONDO:0015439","xrefs":{"Monarch":{"xref_id":"0015439"}}}


id: GO:0045699
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of synergid cell differentiation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell differentiation","termid":"GO:0045597"},{"relation_name":"is_a","term_name":"regulation of synergid differentiation","termid":"GO:0045697"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"positively_regulates","term_name":"synergid differentiation","termid":"GO:0009563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of synergid differentiation","synonyms":[{"name":"activation of synergid differentiation","type":"narrow"},{"name":"positive regulation of synergid cell differentiation","type":"exact"},{"name":"stimulation of synergid differentiation","type":"narrow"},{"name":"up regulation of synergid differentiation","type":"exact"},{"name":"up-regulation of synergid differentiation","type":"exact"},{"name":"upregulation of synergid differentiation","type":"exact"}],"termid":"GO:0045699"}


id: FYPO:0000220
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere outer repeat region are present at greater levels than normal.","definition_xrefs":["PomBase:mah","PMID:20211136"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased centromeric transcript level","termid":"FYPO:0004982"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0006551","FYPO:0000002","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"increased centromeric outer repeat transcript level","synonyms":[{"name":"increased accumulation of centromeric outer repeat transcripts","type":"related"},{"name":"increased accumulation of centromeric outer repeat transcripts during vegetative growth","type":"related"},{"name":"increased accumulation of non-coding outer repeat transcripts","type":"exact"},{"name":"increased centromere outer repeat transcript level","type":"exact"},{"name":"increased centromeric outer repeat transcript level during mitotic cell cycle","type":"related"},{"name":"increased centromeric outer repeat transcript level during vegetative growth","type":"exact"},{"name":"increased centromeric outer repeat-derived transcript level","type":"exact"},{"name":"increased level of centromeric outer repeat transcripts","type":"exact"}],"termid":"FYPO:0000220"}


id: GO:0048922
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.","definition_xrefs":["PMID:15832385"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuromast deposition","termid":"GO:0048885"},{"relation_name":"part_of","term_name":"posterior lateral line neuromast development","termid":"GO:0048919"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"posterior lateral line neuromast deposition","termid":"GO:0048922"}


id: GO:0120332
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The biological process involved in maintaining the steady-state number of cells within a population of free-living cells, such as the bacteria, in the mouth.","definition_xrefs":["PMID:31882545"],"direct_ancestors":[{"relation_name":"is_a","term_name":"homeostasis of number of cells","termid":"GO:0048872"},{"relation_name":"is_a","term_name":"host-mediated perturbation of symbiont process","termid":"GO:0051851"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"host-mediated regulation of oral microbiota composition","synonyms":[{"name":"host-induced regulation of oral microbiota composition","type":"related"}],"termid":"GO:0120332"}


id: GO:0018321
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose.","definition_xrefs":["GOC:pr","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein glycosylation","termid":"GO:0006486"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006486"}],"interesting_parent_ids":["GO:0008150","GO:0006486"],"is_obsolete":false,"name":"protein glucuronylation","synonyms":[{"name":"protein amino acid glucuronylation","type":"exact"}],"termid":"GO:0018321"}


id: GO:0019256
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.","definition_xrefs":["PMID:1390687","PMID:3830164","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xenobiotic catabolic process","termid":"GO:0042178"},{"relation_name":"is_a","term_name":"nitrile catabolic process","termid":"GO:0050899"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"acrylonitrile catabolic process","secondary_identifiers":["MetaCyc:P344-PWY","UM-BBD_pathwayID:acr"],"synonyms":[{"name":"acrylonitrile breakdown","type":"exact"},{"name":"acrylonitrile catabolism","type":"exact"},{"name":"acrylonitrile degradation","type":"exact"}],"termid":"GO:0019256"}


id: GO:0019909
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binds to and modulates of the activity of [pyruvate dehydrogenase (lipoamide)] phosphatase.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity (obsolete GO:0019909)","synonyms":[{"name":"[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity","type":"narrow"}],"termid":"GO:0019909"}


id: PBO:0041408
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 6 open reading frame 141","termid":"PBO:0041408"}


id: FYPO:0007083
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a short meiotic spindle assembles, and may begin elongation, but does not elongate normally or completely, and eventually collapses. Upon collapse the spindle may break or shrink.","definition_xrefs":["PMID:31532702","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiosis I","termid":"FYPO:0003603"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000631","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"meiotic spindle collapse","synonyms":[{"name":"broken meiotic spindle","type":"related"},{"name":"meiotic spindle breakage","type":"exact"},{"name":"spindle collapse during meiosis","type":"exact"},{"name":"spindle collapse during meiotic cell cycle","type":"related"}],"termid":"FYPO:0007083"}


id: GO:0034932
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-methoxypyrene 6,7-monooxygenase activity (obsolete GO:0034932)","termid":"GO:0034932"}


id: PBO:0084346
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Largest subunit of the origin recognition complex; involved in directing DNA replication by binding to replication origins; also involved in transcriptional silencing; exhibits ATPase activity; ORC1 has a paralog, SIR3, that arose from the whole genome duplication","termid":"PBO:0084346"}


id: GO:0016064
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An immune response mediated by immunoglobulins, whether cell-bound or in solution.","definition_xrefs":["GO_REF:0000022","GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"B cell mediated immunity","termid":"GO:0019724"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"immunoglobulin mediated immune response","synonyms":[{"name":"antibody-mediated immune response","type":"exact"}],"termid":"GO:0016064"}


id: PBO:0116657
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARF like GTPase 4A","termid":"PBO:0116657"}


id: MONDO:0013724
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any bacteremia, susceptibility in which the cause of the disease is a mutation in the CISH gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacteremia, susceptibility","termid":"MONDO:0000108"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bacteremia, susceptibility to, 2","secondary_identifiers":["MEDGEN:482277","OMIM:614383","UMLS:C3280647"],"synonyms":[{"name":"BACTS2","type":"related"},{"name":"CISH bacteremia, susceptibility","type":"exact"},{"name":"bacteremia, susceptibility caused by mutation in CISH","type":"exact"},{"name":"bacteremia, susceptibility to","type":"exact"},{"name":"bacteremia, susceptibility to, 2","type":"exact"},{"name":"bacteremia, susceptibility to, type 2","type":"exact"}],"termid":"MONDO:0013724","xrefs":{"Monarch":{"xref_id":"0013724"}}}


id: PBO:0039157
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenylate kinase 4 pseudogene 4","termid":"PBO:0039157"}


id: PBO:0089140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterochromatin (HP1) family chromodomain protein Chp2","termid":"PBO:0089140"}


id: PBO:0046173
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ELK1 pseudogene 1","termid":"PBO:0046173"}


id: MONDO:0011472
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Epidermolysis bullosa simplex due to plakophilin deficiency (EBS-PD) is a suprabasal subtype of epidermolysis bullosa simplex (EBS) characterized by generalized superficial erosions and less commonly blistering.","definition_xrefs":["Orphanet:158668"],"direct_ancestors":[{"relation_name":"is_a","term_name":"suprabasal epidermolysis bullosa simplex","termid":"MONDO:0015550"},{"relation_name":"is_a","term_name":"ectodermal dysplasia syndrome","termid":"MONDO:0019287"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"epidermolysis bullosa simplex due to plakophilin deficiency","secondary_identifiers":["MEDGEN:388032","SCTID:716699004","OMIM:604536","UMLS:C1858302","GARD:9705","MESH:C536183"],"synonyms":[{"name":"McGrath syndrome","type":"exact"},{"name":"Mcgrath syndrome","type":"related"},{"name":"ectodermal dysplasia - skin fragility syndrome","type":"related"},{"name":"ectodermal dysplasia skin fragility syndrome","type":"related"},{"name":"ectodermal dysplasia-skin fragility syndrome","type":"exact"},{"name":"ectodermal dysplasia/skin fragility syndrome","type":"related"}],"termid":"MONDO:0011472","xrefs":{"Monarch":{"xref_id":"0011472"}}}


id: GO:0043226
data:
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