# terms

id: MOD:01512
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a threonine residue with the Applied Biosystems iTRAQ4plex-117 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated residue","termid":"MOD:01506"},{"relation_name":"is_a","term_name":"iTRAQ4plex reporter+balance reagent O-acylated residue","termid":"MOD:01713"},{"relation_name":"is_a","term_name":"O3-acylated L-threonine","termid":"MOD:02004"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ4plex-117 reporter+balance reagent O3-acylated threonine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"iTRAQ4plex","type":"related"}],"termid":"MOD:01512"}


id: PR:Q4LB35
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fol1 gene.","definition_xrefs":["UniProtKB:Q4LB35","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"folic acid synthesis protein fol1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1734.03","synonyms":[{"name":"Spom972h-fol1","type":"exact"}],"termid":"PR:Q4LB35"}


id: PBO:0012846
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exosome subunit Rrp46","termid":"PBO:0012846"}


id: PBO:0057880
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3184","termid":"PBO:0057880"}


id: FYPO:0008063
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases abnormally, or does not change, immediately following osmotic shock. Normally, the intracellular Ca2+ concentration increases to a peak in a \\\"burst\\\" within one minute, and then decreases to a new steady-state concentration.","definition_xrefs":["PMID:36200871"],"direct_ancestors":[{"relation_name":"is_a","term_name":"altered cellular calcium level","termid":"FYPO:0001462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased immediate intracellular calcium spike following osmotic shock","termid":"FYPO:0008063"}


id: PBO:0035933
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein-protein_interaction_during_cellular_response_to_hypoxia","termid":"PBO:0035933"}


id: SO:0000348
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An attribute describing a sequence consisting of nucleobases bound to repeating units. The forms found in nature are deoxyribonucleic acid (DNA), where the repeating units are 2-deoxy-D-ribose rings connected to a phosphate backbone, and ribonucleic acid (RNA), where the repeating units are D-ribose rings connected to a phosphate backbone.","definition_xrefs":["CHEBI:33696","RSC:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polymer_attribute","termid":"SO:0000443"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleic_acid","secondary_identifiers":["http://en.wikipedia.org/wiki/Nucleic_acid"],"synonyms":[{"name":"nucleic acid","type":"exact"}],"termid":"SO:0000348"}


id: MONDO:0018864
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disorder, characterized by regional cervical lymphadenopathy with tenderness, usually accompanied with mild fever and night sweats. Less frequent symptoms include weight loss, nausea, vomiting, sore throat.","definition_xrefs":["Orphanet:50918"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lymphadenitis","termid":"MONDO:0002052"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"Kikuchi-Fujimoto disease","secondary_identifiers":["NCIT:C71719","MEDGEN:97979","UMLS:C0398367","SCTID:127217009","GARD:6834","MESH:D020042"],"synonyms":[{"name":"Kikuchi disease","type":"exact"},{"name":"Kikuchi necrotizing lymphadenitis","type":"related"},{"name":"Kikuchi's disease","type":"related"},{"name":"Kikuchi-Fujimoto's disease","type":"related"},{"name":"histiocytic necrotising lymphadenitis","type":"related"},{"name":"histiocytic necrotizing lymphadenitis","type":"exact"},{"name":"nosocomial Kikuchi's disease","type":"related"}],"termid":"MONDO:0018864","xrefs":{"Monarch":{"xref_id":"0018864"}}}


id: GO:0080057
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Vascular tissue pattern formation as it occurs in the sepal of vascular plants.","definition_xrefs":["PMID:17369435"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xylem and phloem pattern formation","termid":"GO:0010051"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sepal vascular tissue pattern formation","termid":"GO:0080057"}


id: GO:0048453
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"floral organ formation","termid":"GO:0048449"},{"relation_name":"part_of","term_name":"sepal morphogenesis","termid":"GO:0048447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sepal formation","secondary_identifiers":["GO:0048423"],"termid":"GO:0048453"}


id: GO:0042704
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovulation cycle process","termid":"GO:0022602"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"uterine wall breakdown","termid":"GO:0042704"}


id: PBO:0061338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore complex interacting protein pseudogene 1","termid":"PBO:0061338"}


id: GO:0016530
data:
  {"annotated_genes":["SJAG_03296","SJAG_00532","SJAG_04553","SJAG_01418","SJAG_03231","SJAG_00449","SJAG_04403","SJAG_02895","SJAG_03862","SJAG_02994"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[68090,68436],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140663"},{"annotations":[89370,61598,102442,105033],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016531"},{"annotations":[100900,71827],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034986"},{"annotations":[93307],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140132"},{"annotations":[93481],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016532"}]},"cv_name":"molecular_function","definition":"Binding to and delivering metal ions to a target protein.","definition_xrefs":["PMID:11739376"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molecular carrier activity","termid":"GO:0140104"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00449":null,"SJAG_00532":null,"SJAG_01418":null,"SJAG_02895":null,"SJAG_02994":null,"SJAG_03231":null,"SJAG_03296":null,"SJAG_03862":null,"SJAG_04403":null,"SJAG_04553":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140104"}],"interesting_parent_ids":["GO:0003674","GO:0140104"],"is_obsolete":false,"name":"metallochaperone activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0016530","terms_by_termid":{"GO:0016531":null,"GO:0016532":null,"GO:0034986":null,"GO:0140132":null,"GO:0140663":null}}


id: PBO:0082239
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha-SNAP cochaperone; SNARE-complex adaptor for Sec18 (NSF) during the disassembly of postfusion cis-SNARE complexes; stimulates the ATPase activity of Sec18p; peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; similar to mammalian alpha-SNAP","termid":"PBO:0082239"}


id: GO:0007320
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The introduction of semen or sperm into the genital tract of a female.","definition_xrefs":["ISBN:0582227089"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multi-organism reproductive process","termid":"GO:0044703"},{"relation_name":"is_a","term_name":"multi-multicellular organism process","termid":"GO:0044706"},{"relation_name":"is_a","term_name":"multicellular organismal reproductive process","termid":"GO:0048609"},{"relation_name":"part_of","term_name":"copulation","termid":"GO:0007620"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"insemination","secondary_identifiers":["Wikipedia:Insemination"],"termid":"GO:0007320"}


id: PBO:0055058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2474","termid":"PBO:0055058"}


id: PBO:0042890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CFAP418 antisense RNA 1","termid":"PBO:0042890"}


id: GO:0075024
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont phospholipase C-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete phospholipase C-mediated activation of appressorium formation (obsolete GO:0075024)","termid":"GO:0075024"}


id: MONDO:0009563
data:
  {"annotated_genes":["SJAG_02433","SJAG_03290"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85479],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014057"},{"annotations":[85568],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009529"}]},"cv_name":"mondo","definition":"An autosomal recessive inherited disorder caused by mutations in the BCKDHA, BCKDHB, DBT, and DLD genes. It is characterized by a deficiency of branched-chain alpha-keto acid dehydrogenase complex, leading to accumulation of metabolites in the body fluids. The name of the disease derives from the sweet odor of the urine in infants, reminiscent of maple syrup. Signs and symptoms usually appear in infancy and include lethargy and developmental delays. If untreated, it may lead to seizures, coma, and death.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn organic aciduria","termid":"MONDO:0000688"},{"relation_name":"is_a","term_name":"inborn disorder of branched-chain amino acid metabolism","termid":"MONDO:0019242"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02433":null,"SJAG_03290":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"maple syrup urine disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C34806","DOID:9269","NORD:1400","MEDGEN:6217","ICD10CM:E71.0","MedDRA:10026817","MESH:D008375","NANDO:2200473","UMLS:C0024776","Orphanet:511","OMIMPS:248600","GARD:3228","SCTID:27718001","icd11.foundation:1623706568","NANDO:1200791"],"synonyms":[{"name":"BCKD deficiency","type":"exact"},{"name":"BCKDH deficiency","type":"exact"},{"name":"Keto acid decarboxylase deficiency","type":"related"},{"name":"Ketoacidaemia","type":"exact"},{"name":"MSUD","type":"exact"},{"name":"branched chain ketoaciduria","type":"exact"},{"name":"branched-chain 2-ketoacid dehydrogenase deficiency","type":"exact"},{"name":"branched-chain Alpha-Keto acid dehydrogenase deficiency","type":"related"},{"name":"branched-chain ketoaciduria","type":"exact"},{"name":"dihydrolipoamide dehydrogenase deficiency","type":"related"},{"name":"maple syrup urine disease","type":"exact"},{"name":"maple syrup urine disease, Intermediate","type":"related"},{"name":"maple syrup urine disease, classic","type":"related"},{"name":"maple syrup urine disease, intermittent","type":"related"},{"name":"maple syrup urine disease, thiamine-responsive","type":"related"},{"name":"maple syrup urine disease, type 1A","type":"narrow"},{"name":"maple syrup urine disease, type 1B","type":"narrow"},{"name":"maple syrup urine disease, type 2","type":"narrow"}],"termid":"MONDO:0009563","terms_by_termid":{"MONDO:0009529":null,"MONDO:0014057":null},"xrefs":{"Monarch":{"xref_id":"0009563"}}}


id: PBO:0046099
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 4B pseudogene 2","termid":"PBO:0046099"}


id: MONDO:0005102
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive malignant mesenchymal neoplasm that arises from the liver and usually occurs in older children. It is composed of immature spindle, stellate, polymorphous, and giant cells.","definition_xrefs":["NCIT:C27096"],"direct_ancestors":[{"relation_name":"is_a","term_name":"liver sarcoma","termid":"MONDO:0002397"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515","MONDO:0004992"],"is_obsolete":false,"name":"undifferentiated (embryonal) sarcoma","secondary_identifiers":["EFO:0000730","NANDO:2200058","UMLS:C0855073","ICDO:8991/3","MEDGEN:163512","ICDO:8805/3"],"synonyms":[{"name":"UES","type":"exact"},{"name":"embryonal sarcoma","type":"exact"},{"name":"embryonal sarcoma (undifferentiated sarcoma)","type":"exact"},{"name":"embryonal sarcoma, undifferentiated","type":"exact"},{"name":"sarcoma, undifferentiated, malignant","type":"exact"},{"name":"undifferentiated (embryonal) sarcoma","type":"exact"},{"name":"undifferentiated sarcoma","type":"exact"}],"termid":"MONDO:0005102","xrefs":{"Monarch":{"xref_id":"0005102"}}}


id: PBO:0076318
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptopodin 2","termid":"PBO:0076318"}


id: PBO:0088112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway; protein increases in abundance and relative distribution to cytoplasmic foci increases upon DNA replication stress","termid":"PBO:0088112"}


id: PBO:0109370
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed transcript, Y-linked 5","termid":"PBO:0109370"}


id: PBO:0091303
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"splicing of all introns, including intron IV, introduces stop codon that leads to production of mitochondrial hydrolase instead of tandem hydrolase/cardiolipin fusion protein","termid":"PBO:0091303"}


id: MONDO:0012667
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the VCL gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated dilated cardiomyopathy","termid":"MONDO:0700335"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"dilated cardiomyopathy 1W","secondary_identifiers":["UMLS:C1969639","OMIM:611407","GARD:15515","MEDGEN:370063","DOID:0110446","MESH:C566954"],"synonyms":[{"name":"CMD1W","type":"exact"},{"name":"VCL familial isolated dilated cardiomyopathy","type":"exact"},{"name":"cardiomyopathy, dilated, 1W","type":"related"},{"name":"cardiomyopathy, dilated, type 1W","type":"exact"},{"name":"dilated cardiomyopathy type 1W","type":"exact"},{"name":"familial isolated dilated cardiomyopathy caused by mutation in VCL","type":"exact"}],"termid":"MONDO:0012667","xrefs":{"Monarch":{"xref_id":"0012667"}}}


id: MONDO:0009196
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare deafness characterized by the association of bilateral sensorineural hearing loss and white hair with scattered black tufts, as well as skin areas of hyper- and hypopigmentation. Additional reported features include global developmental delay and moderate intellectual disability, growth retardation, microcephaly, hypotonia, mild dysmorphic facial features (deeply set eyes, broad nasal bridge, slight bowing of the upper lip), retinal depigmentation, anomalies of the fingers and toes, and white matter abnormalities on brain imaging.","definition_xrefs":["Orphanet:999"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ermine phenotype","secondary_identifiers":["icd11.foundation:2048725507","OMIM:227010","ICD9:270.2","UMLS:C1856899","GARD:407","MEDGEN:346466","MESH:C535508","SCTID:10170007","ICD10CM:E70.3","MESH:C562663"],"synonyms":[{"name":"BADS","type":"related"},{"name":"BADS syndrome","type":"related"},{"name":"O'Doherty syndrome","type":"exact"},{"name":"black locks with albinism and deafness syndrome","type":"related"},{"name":"black locks, oculocutaneous albinism, and deafness of the sensorineural type","type":"related"},{"name":"ermine phenotype","type":"exact"},{"name":"pigmentary disorder with hearing loss","type":"exact"}],"termid":"MONDO:0009196","xrefs":{"Monarch":{"xref_id":"0009196"}}}


id: PBO:0057997
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3921","termid":"PBO:0057997"}


id: GO:0030879
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.","definition_xrefs":["PMID:9576833"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gland development","termid":"GO:0048732"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mammary gland development","synonyms":[{"name":"mammogenesis","type":"narrow"}],"termid":"GO:0030879"}


id: PBO:0088720
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein subunit S4","termid":"PBO:0088720"}


id: GO:1901966
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation.","definition_xrefs":["GOC:TermGenie","PMID:23115244"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to nutrient levels","termid":"GO:0032107"},{"relation_name":"is_a","term_name":"regulation of cellular response to stress","termid":"GO:0080135"},{"relation_name":"regulates","term_name":"cellular response to iron ion starvation","termid":"GO:0010106"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cellular response to iron ion starvation","termid":"GO:1901966"}


id: PBO:0043423
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclic nucleotide gated channel subunit alpha 1","termid":"PBO:0043423"}


id: GO:0102773
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete dihydroceramide kinase activity (obsolete GO:0102773)","termid":"GO:0102773"}


id: PBO:0048263
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polypeptide N-acetylgalactosaminyltransferase 1","termid":"PBO:0048263"}


id: MONDO:0001635
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, benign neoplasm of bladder that is composed of papillary cores with overlying histologically benign squamous epithelium.","definition_xrefs":["NCIT:C39834"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bladder benign neoplasm","termid":"MONDO:0000384"},{"relation_name":"is_a","term_name":"squamous papilloma","termid":"MONDO:0001825"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bladder squamous papilloma","secondary_identifiers":["MEDGEN:267742","DOID:13110","UMLS:C1511199"],"synonyms":[{"name":"bladder squamous papilloma","type":"exact"}],"termid":"MONDO:0001635","xrefs":{"Monarch":{"xref_id":"0001635"}}}


id: PBO:0082804
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex","termid":"PBO:0082804"}


id: MONDO:0017765
data:
  {"annotated_genes":["SJAG_03371"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85949],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0859328"}]},"cv_name":"mondo","definition":"An inherited metabolic disease that is has its basis in the disruption of magnesium ion transport.","definition_xrefs":["MONDO:patterns/inborn_metabolic"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of mineral absorption and transport","termid":"MONDO:0017761"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03371":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"disorder of magnesium transport","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:21357","Orphanet:309848","MEDGEN:1842842","UMLS:C5681030"],"synonyms":[{"name":"inborn error of magnesium ion transport","type":"exact"},{"name":"inborn magnesium ion transport disorder","type":"exact"},{"name":"rare inborn error of magnesium ion transport","type":"exact"}],"termid":"MONDO:0017765","terms_by_termid":{"MONDO:0859328":null},"xrefs":{"Monarch":{"xref_id":"0017765"}}}


id: GO:0047010
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H+ + NADH.","definition_xrefs":["RHEA:10516","EC:1.1.1.166"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"hydroxycyclohexanecarboxylate dehydrogenase activity","secondary_identifiers":["MetaCyc:1.1.1.166-RXN","KEGG_REACTION:R05315"],"synonyms":[{"name":"(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity","type":"related"},{"name":"(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity","type":"related"},{"name":"dihydroxycyclohexanecarboxylate dehydrogenase activity","type":"related"}],"termid":"GO:0047010"}


id: GO:0032476
data:
  {"annotated_genes":["SJAG_02163","SJAG_00554","SJAG_04568","SJAG_01865"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[74832,72316],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904423"},{"annotations":[114050,92165],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032478"}]},"cv_name":"cellular_component","definition":"A complex that possesses polyprenyl diphosphate synthase activity involved in the synthesis of the isoprenoid chain of ubiquinone whose length varies between organisms.","definition_xrefs":["PMID:14519123","GOC:mah","PMID:16262699"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase complex","termid":"GO:1990234"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00554":null,"SJAG_01865":null,"SJAG_02163":null,"SJAG_04568":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"polyprenyl diphosphate synthase complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"decaprenyl diphosphate synthase complex","type":"narrow"}],"termid":"GO:0032476","terms_by_termid":{"GO:0032478":null,"GO:1904423":null}}


id: PBO:0048554
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamine--fructose-6-phosphate transaminase 1","termid":"PBO:0048554"}


id: GO:0007375
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Internalization of the anterior midgut into the interior of the embryo.","definition_xrefs":["ISBN:0879694238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"morphogenesis of embryonic epithelium","termid":"GO:0016331"},{"relation_name":"part_of","term_name":"gastrulation involving germ band extension","termid":"GO:0010004"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"anterior midgut invagination","termid":"GO:0007375"}


id: GO:0043395
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proteoglycan binding","termid":"GO:0043394"},{"relation_name":"is_a","term_name":"sulfur compound binding","termid":"GO:1901681"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"heparan sulfate proteoglycan binding","synonyms":[{"name":"heparin proteoglycan binding","type":"related"}],"termid":"GO:0043395"}


id: PBO:0072176
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S16 pseudogene 3","termid":"PBO:0072176"}


id: PBO:0052559
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLRK1 antisense RNA 1","termid":"PBO:0052559"}


id: PBO:0053569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 587","termid":"PBO:0053569"}


id: PBO:0052034
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"junctional sarcoplasmic reticulum protein 1","termid":"PBO:0052034"}


id: FYPO:0003980
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of glutathione transferase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal catalytic activity","termid":"FYPO:0000661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0001985","FYPO:0000661","FYPO:0000654","FYPO:0000652"],"is_obsolete":false,"name":"abnormal glutathione transferase activity","termid":"FYPO:0003980"}


id: PBO:0040009
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADP ribosylation factor like GTPase 17A","termid":"PBO:0040009"}


id: MONDO:0016940
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chromosome 3p duplication is a chromosome abnormality that occurs when there is an extra copy of genetic material on the short arm (p) of chromosome 3. The severity of the condition and the signs and symptoms depend on the size and location of the duplication and which genes are involved. Features that often occur in people with chromosome 3p duplication include developmental delay, intellectual disability, behavioral problems and distinctive facial features. Chromosome 3p duplication can be de novo or inherited from a parent with a balanced translocation. Treatment is based on the signs and symptoms present in each person.","definition_xrefs":["GARD:0005343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial duplication of chromosome 3","termid":"MONDO:0016923"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial duplication of the short arm of chromosome 3","secondary_identifiers":["MEDGEN:1826042","MESH:C536811","Orphanet:262707","UMLS:C5679720","GARD:5343","icd11.foundation:514472294"],"synonyms":[{"name":"3p duplication","type":"related"},{"name":"3p trisomy","type":"related"},{"name":"Duplication 3p","type":"related"},{"name":"chromosome 3p duplication","type":"related"},{"name":"partial duplication of chromosome 3p","type":"exact"},{"name":"partial duplication of the short arm of chromosome type 3","type":"exact"},{"name":"partial trisomy 3p","type":"related"},{"name":"partial trisomy of chromosome 3p","type":"exact"},{"name":"partial trisomy of the short arm of chromosome 3","type":"exact"},{"name":"trisomy 3p","type":"related"}],"termid":"MONDO:0016940","xrefs":{"Monarch":{"xref_id":"0016940"}}}


id: GO:1903655
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any phosphorylation of RNA polymerase II C-terminal domain serine 2 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter.","definition_xrefs":["GO_REF:0000060","GOC:TermGenie","PMID:19328067"],"gene_count":0,"genotype_count":0,"name":"obsolete phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter (obsolete GO:1903655)","termid":"GO:1903655"}


id: PBO:0011143
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondria microtubule binder Mmb1","termid":"PBO:0011143"}


id: FYECO:0000225
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which uracil was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ ura","synonyms":[{"name":"uracil added","type":"exact"}],"termid":"FYECO:0000225"}


id: MONDO:0014240
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any periventricular nodular heterotopia in which the cause of the disease is a mutation in the ERMARD gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"periventricular nodular heterotopia","termid":"MONDO:0020341"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"periventricular nodular heterotopia 6","secondary_identifiers":["UMLS:C3809872","GARD:15983","MEDGEN:816202","OMIM:615544"],"synonyms":[{"name":"ERMARD periventricular nodular heterotopia","type":"exact"},{"name":"PVNH6","type":"related"},{"name":"periventricular nodular heterotopia 6","type":"exact"},{"name":"periventricular nodular heterotopia caused by mutation in ERMARD","type":"exact"},{"name":"periventricular nodular heterotopia type 6","type":"exact"}],"termid":"MONDO:0014240","xrefs":{"Monarch":{"xref_id":"0014240"}}}


id: PBO:0069904
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1195, pseudogene","termid":"PBO:0069904"}


id: PBO:0091989
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiosis specific Smp foci lncRNA","termid":"PBO:0091989"}


id: PR:P79088
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein transport protein Sec61 subunit alpha isoform 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02501","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein transport protein sec61 subunit alpha (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC354.02c","secondary_identifiers":["UniProtKB:P79088"],"synonyms":[{"name":"Spom972h-SEC61A1","type":"exact"}],"termid":"PR:P79088"}


id: GO:0075245
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of sexual sporulation resulting in formation of a cellular spore","termid":"GO:0043941"},{"relation_name":"is_a","term_name":"regulation of oospore formation","termid":"GO:0075244"},{"relation_name":"positively_regulates","term_name":"oospore formation","termid":"GO:0075243"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"positive regulation of oospore formation","termid":"GO:0075245"}


id: GO:0047256
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H+ + UDP.","definition_xrefs":["RHEA:13905"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetylglucosaminyltransferase activity","termid":"GO:0008375"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity","secondary_identifiers":["EC:2.4.1.206","MetaCyc:2.4.1.206-RXN","Reactome:R-HSA-9846501"],"synonyms":[{"name":"LA2 synthase activity","type":"related"},{"name":"UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity","type":"related"},{"name":"beta1->3-N-acetylglucosaminyltransferase activity","type":"related"},{"name":"lactosylceramide beta-acetylglucosaminyltransferase activity","type":"related"},{"name":"uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity","type":"related"}],"termid":"GO:0047256"}


id: MONDO:0100525
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A newly discovered disorder caused by a change (variant or mutation) in the TCF7L2 gene. This mutation may be responsible for developmental delays in childhood, intellectual disability, autism, myopia, ADHD, abnormal physical features and other problems. There is a wide spectrum of severity for individuals affected with TRND. Many of the symptoms of TRND overlap with other neurodevelopmental disorders. TRND must be diagnosed with a genetic test and cannot be diagnosed by symptoms alone.","definition_xrefs":["PMID:34003604"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurodevelopmental disorder","termid":"MONDO:0700092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"TCF7L2-related neurodevelopmental disorder","termid":"MONDO:0100525","xrefs":{"Monarch":{"xref_id":"0100525"}}}


id: GO:1905455
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:27010503"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of hematopoietic progenitor cell differentiation","termid":"GO:1901534"},{"relation_name":"is_a","term_name":"regulation of myeloid progenitor cell differentiation","termid":"GO:1905453"},{"relation_name":"positively_regulates","term_name":"myeloid progenitor cell differentiation","termid":"GO:0002318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of myeloid progenitor cell differentiation","synonyms":[{"name":"activation of myeloid progenitor cell differentiation","type":"narrow"},{"name":"up regulation of myeloid progenitor cell differentiation","type":"exact"},{"name":"up-regulation of myeloid progenitor cell differentiation","type":"exact"},{"name":"upregulation of myeloid progenitor cell differentiation","type":"exact"}],"termid":"GO:1905455"}


id: FYPO:0004097
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction is normal (i.e. indistinguishable from wild type). Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts.","definition_xrefs":["GO:1902404","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal mitotic cell cycle process","termid":"FYPO:0002741"},{"relation_name":"is_a","term_name":"normal actomyosin contractile ring organization","termid":"FYPO:0007827"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal actomyosin contractile ring contraction","synonyms":[{"name":"normal actomyosin contractile ring constriction","type":"exact"},{"name":"normal actomyosin contractile ring contraction during mitotic cell cycle","type":"related"},{"name":"normal actomyosin contractile ring contraction during vegetative growth","type":"exact"},{"name":"normal contractile ring contraction","type":"exact"},{"name":"normal cytokinetic contractile ring contraction","type":"exact"},{"name":"normal mitotic actomyosin contractile ring contraction","type":"exact"},{"name":"normal mitotic contractile ring contraction","type":"exact"}],"termid":"FYPO:0004097"}


id: PBO:0002945
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation initiation factor eIF2B gamma subunit (predicted)","termid":"PBO:0002945"}


id: MONDO:0004657
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"chorioretinitis","termid":"MONDO:0004674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"disseminated chorioretinitis","secondary_identifiers":["MEDGEN:509696","DOID:8787","ICD9:363.1","SCTID:78769001","UMLS:C0154879","ICD9:363.10"],"termid":"MONDO:0004657","xrefs":{"Monarch":{"xref_id":"0004657"}}}


id: GO:0010430
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.","definition_xrefs":["MetaCyc:PWY-2724","PMID:16404574"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fatty acid oxidation","termid":"GO:0019395"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006629","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"fatty acid omega-oxidation","termid":"GO:0010430"}


id: PBO:0044419
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 2 subfamily W member 1","termid":"PBO:0044419"}


id: GO:1904021
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.","definition_xrefs":["PMID:24732013","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of receptor internalization","termid":"GO:0002091"},{"relation_name":"is_a","term_name":"regulation of G protein-coupled receptor internalization","termid":"GO:1904020"},{"relation_name":"negatively_regulates","term_name":"G protein-coupled receptor internalization","termid":"GO:0002031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"negatively_regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0016192","GO:0023052","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of G protein-coupled receptor internalization","synonyms":[{"name":"down regulation of G-protein coupled receptor internalization","type":"exact"},{"name":"down-regulation of G-protein coupled receptor internalization","type":"exact"},{"name":"downregulation of G-protein coupled receptor internalization","type":"exact"},{"name":"inhibition of G-protein coupled receptor internalization","type":"narrow"},{"name":"negative regulation of G-protein coupled receptor internalization","type":"exact"}],"termid":"GO:1904021"}


id: GO:0047332
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H+ + phosphate.","definition_xrefs":["RHEA:23764","EC:2.7.1.80"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0016301","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"diphosphate-serine phosphotransferase activity","secondary_identifiers":["MetaCyc:2.7.1.80-RXN","KEGG_REACTION:R00584"],"synonyms":[{"name":"diphosphate:L-serine O-phosphotransferase activity","type":"related"},{"name":"pyrophosphate--serine phosphotransferase activity","type":"related"},{"name":"pyrophosphate-L-serine phosphotransferase activity","type":"related"}],"termid":"GO:0047332"}


id: PATO:0001190
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A maturity quality inhering in a bearer by virtue the bearer's being not fully grown or developed.","definition_xrefs":["thefreedictionary.com:thefreedictionary.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maturity","termid":"PATO:0000261"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"juvenile","termid":"PATO:0001190"}


id: FYPO:0004879
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at the centromere central core.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal chromatin binding","termid":"FYPO:0003086"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000702"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000257","FYPO:0000702"],"is_obsolete":false,"name":"normal chromatin binding at centromere central core","termid":"FYPO:0004879"}


id: PBO:0054127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1493","termid":"PBO:0054127"}


id: RO:HOM0000007
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Homology that is defined by common descent.","definition_xrefs":["ISBN:0123195837"],"direct_ancestors":[{"relation_name":"is_a","term_name":"in_homology_relationship_with","termid":"RO:HOM0000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_historical_homology_relationship_with","synonyms":[{"name":"cladistic homology","type":"exact"},{"name":"historical homologous to","type":"exact"},{"name":"homology","type":"broad"},{"name":"phylogenetic homology","type":"exact"},{"name":"taxic homology","type":"exact"},{"name":"true homology","type":"related"}],"termid":"RO:HOM0000007"}


id: PBO:0071112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 114","termid":"PBO:0071112"}


id: GO:0016492
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.","definition_xrefs":["PMID:10390649"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuropeptide receptor activity","termid":"GO:0008188"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"G protein-coupled neurotensin receptor activity","synonyms":[{"name":"G protein coupled neurotensin receptor activity","type":"exact"},{"name":"G-protein coupled neurotensin receptor activity","type":"exact"},{"name":"neurotensin receptor activity, G protein coupled","type":"exact"},{"name":"neurotensin receptor activity, G-protein coupled","type":"exact"}],"termid":"GO:0016492"}


id: SO:0000152
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Yeast Artificial Chromosome, a vector constructed from the telomeric, centromeric, and replication origin sequences needed for replication in yeast cells.","definition_xrefs":["SO:ma"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vector_replicon","termid":"SO:0000440"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"YAC","synonyms":[{"name":"yeast artificial chromosome","type":"exact"}],"termid":"SO:0000152"}


id: PBO:0070357
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY4 pseudogene 30","termid":"PBO:0070357"}


id: GO:1901701
data:
  {"annotated_genes":["SJAG_02515","SJAG_00574","SJAG_04403","SJAG_01216","SJAG_04788","SJAG_02444","SJAG_04632","SJAG_00141","SJAG_04026","SJAG_05256","SJAG_03653","SJAG_01754","SJAG_01199","SJAG_01734","SJAG_00668","SJAG_05181","SJAG_04823","SJAG_03303","SJAG_06611","SJAG_01699","SJAG_01254","SJAG_01457","SJAG_02010","SJAG_00472","SJAG_04953","SJAG_02960","SJAG_03081","SJAG_01162","SJAG_04399","SJAG_04312"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[106228,102167,115833,107164,116861,94564,109830,106814,109325],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010619"},{"annotations":[113040],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0110095"},{"annotations":[95529,105368,109148,117668,118591,100324],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061692"},{"annotations":[105371],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0140041"},{"annotations":[77918],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071244"},{"annotations":[105547],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036245"},{"annotations":[95866,78505],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0046294"},{"annotations":[65297,61028,74670,89744,93478,99599,58085,89322,69224],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0019430"}]},"cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.","definition_xrefs":["GOC:pr","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to chemical stimulus","termid":"GO:0070887"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":30,"genes_by_uniquename":{"SJAG_00141":null,"SJAG_00472":null,"SJAG_00574":null,"SJAG_00668":null,"SJAG_01162":null,"SJAG_01199":null,"SJAG_01216":null,"SJAG_01254":null,"SJAG_01457":null,"SJAG_01699":null,"SJAG_01734":null,"SJAG_01754":null,"SJAG_02010":null,"SJAG_02444":null,"SJAG_02515":null,"SJAG_02960":null,"SJAG_03081":null,"SJAG_03303":null,"SJAG_03653":null,"SJAG_04026":null,"SJAG_04312":null,"SJAG_04399":null,"SJAG_04403":null,"SJAG_04632":null,"SJAG_04788":null,"SJAG_04823":null,"SJAG_04953":null,"SJAG_05181":null,"SJAG_05256":null,"SJAG_06611":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to oxygen-containing compound","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"cellular response to oxygen molecular entity","type":"exact"}],"termid":"GO:1901701","terms_by_termid":{"GO:0010619":null,"GO:0019430":null,"GO:0036245":null,"GO:0046294":null,"GO:0061692":null,"GO:0071244":null,"GO:0110095":null,"GO:0140041":null}}


id: PBO:0083568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified ORF GLE2/YER107C","termid":"PBO:0083568"}


id: GO:0102795
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-naphthaldehyde:oxygen oxidoreductase activity (obsolete GO:0102795)","termid":"GO:0102795"}


id: GO:0047395
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = sn-glycerol 3-phosphate + myo-inositol + H+.","definition_xrefs":["EC:3.1.4.44","RHEA:16501"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphoric diester hydrolase activity","termid":"GO:0008081"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016788","GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"glycerophosphoinositol glycerophosphodiesterase activity","secondary_identifiers":["MetaCyc:3.1.4.44-RXN","Reactome:R-HSA-6813740","KEGG_REACTION:R01193"],"synonyms":[{"name":"1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity","type":"related"},{"name":"sn-glycero(3)phosphoinositol glycerophosphohydrolase activity","type":"related"},{"name":"sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity","type":"related"}],"termid":"GO:0047395"}


id: MONDO:0016186
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"qualitative or quantitative protein defects in neuromuscular diseases","termid":"MONDO:0016139"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"qualitative or quantitative defects of myofibrillar proteins","secondary_identifiers":["MEDGEN:1842566","UMLS:C5680851","GARD:20425","Orphanet:209038"],"termid":"MONDO:0016186","xrefs":{"Monarch":{"xref_id":"0016186"}}}


id: MONDO:0003393
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-neoplastic or neoplastic disorder that affects the thymus. Representative examples include thymic hyperplasia, thymoma, and thymic carcinoma.","definition_xrefs":["NCIT:C26962"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"lymphatic system disorder","termid":"MONDO:0005833"},{"relation_name":"is_a","term_name":"immune system disorder","termid":"MONDO:0005046"},{"relation_name":"is_a","term_name":"endocrine system disorder","termid":"MONDO:0005151"},{"relation_name":"is_a","term_name":"hematologic disorder","termid":"MONDO:0005570"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"thymus gland disorder","secondary_identifiers":["MEDGEN:57585","SCTID:20673009","DOID:533","ICD9:254","ICD9:254.9","UMLS:C0154199"],"synonyms":[{"name":"Thymus disorder","type":"exact"},{"name":"disease of thymus","type":"exact"},{"name":"disease of thymus gland","type":"exact"},{"name":"disease or disorder of thymus","type":"exact"},{"name":"disorder of thymus","type":"exact"},{"name":"disorder of thymus gland","type":"exact"},{"name":"thymus disease","type":"exact"},{"name":"thymus disease or disorder","type":"exact"},{"name":"thymus disorder","type":"related"}],"termid":"MONDO:0003393","xrefs":{"Monarch":{"xref_id":"0003393"}}}


id: MOD:00465
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-phenylalanine residue to a dihydroxyphenylalanine.","definition_xrefs":["PubMed:9252331","OMSSA:39","RESID:AA0146#var","Unimod:425#F","PubMed:1610822","PubMed:3734192","PubMed:1903612"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dihydroxylated residue","termid":"MOD:00428"},{"relation_name":"is_a","term_name":"modified L-phenylalanine residue","termid":"MOD:00914"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dihydroxyphenylalanine (Phe)","synonyms":[{"name":"Dioxidation","type":"related"},{"name":"dihydroxy","type":"related"},{"name":"dihydroxyf","type":"exact"}],"termid":"MOD:00465"}


id: GO:0099563
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modifies the structure/morphology of a synapse.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"synapse organization","termid":"GO:0050808"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"modification of synaptic structure","synonyms":[{"name":"synapse remodelling","type":"exact"}],"termid":"GO:0099563"}


id: PR:Q9HFF4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppk1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9HFF4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine-protein kinase ppk1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC110.01","synonyms":[{"name":"Spom972h-ppk1","type":"exact"}],"termid":"PR:Q9HFF4"}


id: PBO:0030377
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_diamide","termid":"PBO:0030377"}


id: PBO:0059467
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MSH5-SAPCD1 readthrough (NMD candidate)","termid":"PBO:0059467"}


id: PBO:0077480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 200C","termid":"PBO:0077480"}


id: PBO:0017922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CorA family magnesium ion transmembrane transporter (predicted)","termid":"PBO:0017922"}


id: PBO:0077866
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tropomyosin 3 pseudogene 7","termid":"PBO:0077866"}


id: GO:0061675
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.","definition_xrefs":["PMID:22312473"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"RBL family protein binding","synonyms":[{"name":"rhamnose-binding lectin family protein binding","type":"exact"}],"termid":"GO:0061675"}


id: PBO:0005909
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulfonate/alpha-ketoglutare dioxygenase (predicted)","termid":"PBO:0005909"}


id: PBO:0039079
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1-acylglycerol-3-phosphate O-acyltransferase 5 pseudogene 1","termid":"PBO:0039079"}


id: GO:0102738
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate = gibberellin A37 + carbon dioxide + succinate.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete (gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity (obsolete GO:0102738)","termid":"GO:0102738"}


id: GO:0098934
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dendritic transport","termid":"GO:0098935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"retrograde dendritic transport","termid":"GO:0098934"}


id: MONDO:0014836
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Charcot-Marie-Tooth disease in which the cause of the disease is a mutation in the NEFH gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease type 2","termid":"MONDO:0018993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease axonal type 2CC","secondary_identifiers":["DOID:0110180","MEDGEN:934757","OMIM:616924","UMLS:C4310790"],"synonyms":[{"name":"CMT2CC","type":"exact"},{"name":"Charcot-Marie-Tooth disease axonal type 2CC","type":"exact"},{"name":"Charcot-Marie-Tooth disease caused by mutation in NEFH","type":"exact"},{"name":"Charcot-Marie-Tooth disease, axonal, type 2CC","type":"related"},{"name":"Charcot-Marie-Tooth disease, axonal, type 2cc","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy type 2CC","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy, type 2Cc","type":"related"},{"name":"NEFH Charcot-Marie-Tooth disease","type":"exact"}],"termid":"MONDO:0014836","xrefs":{"Monarch":{"xref_id":"0014836"}}}


id: MONDO:0009380
data:
  {"annotated_genes":["SJAG_01344","SJAG_05213","SJAG_03785"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85659,85660,85661],"is_not":false,"summary":null,"term":"MONDO:0009380"}]},"cv_name":"mondo","definition":"Dubin-Johnson syndrome (DJS) is a benign, inherited liver disorder characterized clinically by chronic, predominantly conjugated, hyperbilirubinemia and histopathologically by black-brown pigment deposition in parenchymal liver cells.","definition_xrefs":["Orphanet:234"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary hyperbilirubinemia","termid":"MONDO:0002408"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01344":null,"SJAG_03785":null,"SJAG_05213":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"Dubin-Johnson syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1691610999","MedDRA:10013800","NCIT:C34741","GARD:2793","NORD:1063","MESH:D007566","DOID:12308","OMIM:237500","SCTID:44553005","UMLS:C0022350","MEDGEN:7181"],"synonyms":[{"name":"DJS","type":"related"},{"name":"Dubin Johnson Syndrome","type":"exact"},{"name":"Dubin Johnson syndrome","type":"exact"},{"name":"Dubin-Johnson syndrome","type":"exact"},{"name":"Dubin-Sprinz disease","type":"exact"},{"name":"Sprinz-Nelson syndrome","type":"exact"},{"name":"chronic idiopathic jaundice","type":"exact"},{"name":"conjugated hyperbilirubinemia","type":"related"},{"name":"hyperbilirubinemia 2","type":"related"},{"name":"hyperbilirubinemia type 2","type":"exact"},{"name":"hyperbilirubinemia, Dubin-Johnson type","type":"related"}],"termid":"MONDO:0009380","terms_by_termid":{"MONDO:0009380":null},"xrefs":{"Monarch":{"xref_id":"0009380"}}}


id: PBO:0116726
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PSMD3 antisense RNA 1","termid":"PBO:0116726"}


id: PBO:0040679
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCAR3 antisense RNA 1","termid":"PBO:0040679"}


id: MONDO:0100041
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A type of trimethylaminuria that occurs as the result of treatment with large doses of dietary precursors of the offending chemical. Symptoms develop when the ability of the liver enzyme (flavin-containing monooxygenase 3) is insufficient to break down (metabolize) the excess trimethylamine.","direct_ancestors":[{"relation_name":"is_a","term_name":"trimethylaminuria","termid":"MONDO:0011182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"secondary trimethylaminuria","termid":"MONDO:0100041","xrefs":{"Monarch":{"xref_id":"0100041"}}}


id: PBO:0058692
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6820","termid":"PBO:0058692"}


id: MONDO:0011571
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"dentinogenesis imperfecta type 2","termid":"MONDO:0007441"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deafness, autosomal dominant 39, with dentinogenesis imperfecta 1","secondary_identifiers":["MESH:C565316","OMIM:605594","UMLS:C1854146","GARD:15383","MEDGEN:340145"],"synonyms":[{"name":"Dfna39/Dgi1 syndrome","type":"related"},{"name":"Dfna39/dentinogenesis imperfecta 1 syndrome","type":"related"},{"name":"Dgi1/Dfna39 syndrome","type":"related"},{"name":"deafness, autosomal dominant 39, with dentinogenesis","type":"narrow"},{"name":"deafness, autosomal dominant 39, with dentinogenesis imperfecta 1","type":"exact"},{"name":"deafness, autosomal dominant 39, with dentinogenesis imperfecta type 1","type":"exact"}],"termid":"MONDO:0011571","xrefs":{"Monarch":{"xref_id":"0011571"}}}


id: GO:0102740
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: theobromine + S-adenosyl-L-methionine = H+ + caffeine + S-adenosyl-L-homocysteine.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity (obsolete GO:0102740)","termid":"GO:0102740"}


id: PBO:0044849
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 131D (pseudogene)","termid":"PBO:0044849"}


id: PBO:0043651
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COP9 signalosome subunit 8 pseudogene 1","termid":"PBO:0043651"}


id: MONDO:0003855
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete immature teratoma of ovary (obsolete MONDO:0003855)","termid":"MONDO:0003855","xrefs":{"Monarch":{"xref_id":"0003855"}}}


id: PBO:0065241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline rich 14 like","termid":"PBO:0065241"}


id: MONDO:0800100
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A retinopathy caused by gain of function, heterozygous variants in the RDH12 gene, and associated with late onset retinopathy with a mild phenotype, characterized by nyctalopia and visual field loss, but relatively preserved central vision.","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited retinal dystrophy","termid":"MONDO:0019118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"RDH12-related dominant retinopathy","synonyms":[{"name":"RDH12-related dominant retinopathy","type":"exact"}],"termid":"MONDO:0800100","xrefs":{"Monarch":{"xref_id":"0800100"}}}


id: FYPO:0000119
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which spindle assembly is abnormal. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle.","definition_xrefs":["PomBase:mah","GO:0051225"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromosome segregation","termid":"FYPO:0000029"},{"relation_name":"is_a","term_name":"abnormal microtubule cytoskeleton organization","termid":"FYPO:0000054"},{"relation_name":"is_a","term_name":"abnormal cellular component assembly","termid":"FYPO:0000336"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000054","FYPO:0001985","FYPO:0005447","FYPO:0000631","FYPO:0000002"],"is_obsolete":false,"name":"abnormal spindle assembly","secondary_identifiers":["FYPO:0000285"],"termid":"FYPO:0000119"}


id: PBO:0052183
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KCNK15 and WISP2 antisense RNA 1","termid":"PBO:0052183"}


id: PR:Q9C121
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC1002.20 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9C121"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C1002.20 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.20","synonyms":[{"name":"Spom972h-SPAC1002.20","type":"exact"}],"termid":"PR:Q9C121"}


id: PBO:0066203
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding motif protein 17 pseudogene 4","termid":"PBO:0066203"}


id: GO:0005981
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"is_a","term_name":"regulation of glycogen metabolic process","termid":"GO:0070873"},{"relation_name":"regulates","term_name":"glycogen catabolic process","termid":"GO:0005980"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"regulates","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0006091","GO:0008150"],"is_obsolete":false,"name":"regulation of glycogen catabolic process","synonyms":[{"name":"regulation of glycogen breakdown","type":"exact"},{"name":"regulation of glycogen catabolism","type":"exact"},{"name":"regulation of glycogen degradation","type":"exact"},{"name":"regulation of glycogenolysis","type":"exact"}],"termid":"GO:0005981"}


id: GO:0032508
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.","definition_xrefs":["GOC:isa_complete","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete DNA duplex unwinding (obsolete GO:0032508)","synonyms":[{"name":"DNA unwinding","type":"exact"},{"name":"duplex DNA melting","type":"exact"}],"termid":"GO:0032508"}


id: PBO:0004114
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transketolase (predicted)","termid":"PBO:0004114"}


id: MONDO:0017733
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-mannosidosis","termid":"MONDO:0009561"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002561"}],"interesting_parent_ids":["MONDO:0002561","MONDO:0005328","MONDO:0037792","MONDO:0005066"],"is_obsolete":false,"name":"alpha-mannosidosis, adult form","secondary_identifiers":["NANDO:2201189","SCTID:58112007","UMLS:C5679974","MEDGEN:1843432","GTR:AN0103810","GTR:AN0103811","Orphanet:309288","GARD:17408","NANDO:1200128"],"synonyms":[{"name":"Alpha-mannosidosis adult-onset form","type":"related"},{"name":"lysosomal alpha-D-mannosidase deficiency, adult form","type":"exact"}],"termid":"MONDO:0017733","xrefs":{"Monarch":{"xref_id":"0017733"}}}


id: GO:0048249
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.","definition_xrefs":["PMID:8709965","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphate transmembrane transporter activity","termid":"GO:0005315"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"high-affinity phosphate transmembrane transporter activity","synonyms":[{"name":"high affinity phosphate transmembrane transporter activity","type":"exact"}],"termid":"GO:0048249"}


id: MONDO:0043243
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A white patch or plaque on a mucous membrane that cannot be characterized clinically or pathologically as any other disease. The diagnosis of leukoplakia is one of exclusion; other conditions such as candidiasis, lichen planus, leukoedema, etc., must be ruled out before a diagnosis of leukoplakia can be made. Leukoplakia may be a premalignant condition.","definition_xrefs":["NCIT:C3186"],"direct_ancestors":[{"relation_name":"is_a","term_name":"precancerous condition","termid":"MONDO:0021074"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukoplakia","secondary_identifiers":["SCTID:274134003","UMLS:C0023531","MEDGEN:44133","MESH:D007971"],"synonyms":[{"name":"keratotic plaque","type":"exact"},{"name":"lesion, leukoplakic","type":"related"},{"name":"lesions, leukoplakic","type":"related"},{"name":"leukokeratoses","type":"related"},{"name":"leukokeratosis","type":"related"},{"name":"leukoplakia","type":"exact"},{"name":"leukoplakias","type":"related"},{"name":"leukoplakic lesion","type":"related"},{"name":"leukoplakic lesions","type":"related"}],"termid":"MONDO:0043243","xrefs":{"Monarch":{"xref_id":"0043243"}}}


id: PBO:0034174
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_homoeology_relationship_with","termid":"PBO:0034174"}


id: PBO:0075469
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spermatogenesis associated 20","termid":"PBO:0075469"}


id: PBO:0059344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosomal protein S10 pseudogene 5","termid":"PBO:0059344"}


id: GO:0002265
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.","definition_xrefs":["GOC:add","PMID:11138785"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell activation involved in immune response","termid":"GO:0002263"},{"relation_name":"is_a","term_name":"astrocyte activation","termid":"GO:0048143"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"astrocyte activation involved in immune response","synonyms":[{"name":"astrocyte activation during immune response","type":"related"}],"termid":"GO:0002265"}


id: PBO:0043082
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cholinergic receptor nicotinic beta 2 subunit","termid":"PBO:0043082"}


id: PBO:0046353
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 11","termid":"PBO:0046353"}


id: PBO:0068848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 86, pseudogene","termid":"PBO:0068848"}


id: PBO:0064381
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PMS1 homolog 2, mismatch repair system component pseudogene 3","termid":"PBO:0064381"}


id: MONDO:0014791
data:
  {"annotated_genes":["SJAG_02873"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86142],"is_not":false,"summary":null,"term":"MONDO:0014791"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02873":null},"genotype_count":0,"is_obsolete":false,"name":"Luscan-Lumish syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:597738","GARD:13789","OMIM:616831","UMLS:C4085873","MEDGEN:898669"],"synonyms":[{"name":"LLS","type":"exact"},{"name":"LLs","type":"exact"},{"name":"Luscan-Lumish syndrome","type":"exact"},{"name":"Luscan-Lumish syndrome; LLs","type":"exact"},{"name":"SETD2-related overgrowth syndrome","type":"exact"}],"termid":"MONDO:0014791","terms_by_termid":{"MONDO:0014791":null},"xrefs":{"Monarch":{"xref_id":"0014791"}}}


id: PBO:0052442
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLF transcription factor 2","termid":"PBO:0052442"}


id: PBO:0034023
data:
  {"annotation_feature_type":"gene","cv_name":"pubprop_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"canto_approved_date","termid":"PBO:0034023"}


id: PBO:0059494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"macrophage stimulating 1 receptor","termid":"PBO:0059494"}


id: SO:1000021
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transversion from T to A.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine_to_purine_transversion","termid":"SO:1000018"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T_to_A_transversion","synonyms":[{"name":"T to A transversion","type":"exact"}],"termid":"SO:1000021"}


id: PBO:0054568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1970","termid":"PBO:0054568"}


id: SO:0001306
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"2_methylthio_N6_threonyl_carbamoyladenosine is a modified adenosine.","direct_ancestors":[{"relation_name":"is_a","term_name":"modified_adenosine","termid":"SO:0001273"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"two_methylthio_N6_threonyl_carbamoyladenosine","secondary_identifiers":["RNAMOD:012"],"synonyms":[{"name":"2-methylthio-N6-threonyl carbamoyladenosine","type":"exact"},{"name":"ms2t6A","type":"exact"},{"name":"two methylthio N6 threonyl carbamoyladenosine","type":"exact"}],"termid":"SO:0001306"}


id: FYECO:0000050
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which linoleic acid was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ fatty acid","termid":"FYECO:0000042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ linoleic acid","termid":"FYECO:0000050"}


id: PBO:0031298
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_septum_disassembly","termid":"PBO:0031298"}


id: PBO:0004529
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysine (K) and glutamic acid (E) Rich protein","termid":"PBO:0004529"}


id: PBO:0050948
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interferon alpha 22, pseudogene","termid":"PBO:0050948"}


id: GO:0044465
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism.","definition_xrefs":["GOC:ed","PMID:18579526"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation of sensory perception of pain in another organism (obsolete GO:0044465)","synonyms":[{"name":"modulation of sensory perception of pain in other organism","type":"exact"},{"name":"regulation of sensory perception of pain in another organism","type":"exact"}],"termid":"GO:0044465"}


id: PBO:0030092
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_cell_population_growth_on_dipeptide_nitrogen_source","termid":"PBO:0030092"}


id: PBO:0050733
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family D (Hsp60) member 1 pseudogene 19","termid":"PBO:0050733"}


id: PBO:0052854
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin associated protein 4-11","termid":"PBO:0052854"}


id: GO:0050465
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+.","definition_xrefs":["EC:1.7.1.9","MetaCyc:1.7.1.9-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor","termid":"GO:0046857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"nitroquinoline-N-oxide reductase activity","synonyms":[{"name":"4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity","type":"related"},{"name":"4-nitroquinoline 1-oxide reductase activity","type":"related"},{"name":"4NQO reductase activity","type":"related"},{"name":"NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity","type":"related"},{"name":"NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity","type":"related"}],"termid":"GO:0050465"}


id: MONDO:0007827
data:
  {"annotated_genes":["SJAG_03703","SJAG_02431"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85625,85624],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011577"}]},"cv_name":"mondo","definition":"A slowly progressive degenerative inflammatory disorder of skeletal muscles characterized by late onset weakness of specific muscles and distinctive histopathological features.","definition_xrefs":["Orphanet:611"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myositis disease","termid":"MONDO:0021167"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02431":null,"SJAG_03703":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"inclusion body myositis","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:729.1","SCTID:72315009","MEDGEN:68659","EFO:0007323","MESH:D018979","DOID:3429","ICD9:359.71","MedDRA:10066407","NANDO:1200032","GARD:3896","UMLS:C0238190","NCIT:C84786","NORD:1734","NANDO:1200218","OMIM:147421"],"synonyms":[{"name":"IBM","type":"exact"},{"name":"Ibm","type":"related"},{"name":"Sporadic Inclusion Body Myositis","type":"exact"},{"name":"inclusion body myositis","type":"exact"},{"name":"inflammatory myopathy","type":"related"},{"name":"sIBM","type":"exact"},{"name":"sporadic inclusion body myositis","type":"exact"}],"termid":"MONDO:0007827","terms_by_termid":{"MONDO:0011577":null},"xrefs":{"Monarch":{"xref_id":"0007827"}}}


id: PBO:0089625
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SAGA complex/transcription factor TFIID complex subunit A Taf12","termid":"PBO:0089625"}


id: PBO:0086386
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative calcium channel involved in calcium release under hypotonic stress; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC2 has a paralog, YOR365C, that arose from the whole genome duplication","termid":"PBO:0086386"}


id: FYPO:0006795
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abolished, and some of the protein is present in the nucleus instead.","definition_xrefs":["PMID:11076964","PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"protein mislocalized to nucleus during vegetative growth","termid":"FYPO:0000784"},{"relation_name":"is_a","term_name":"protein mislocalized to nucleus during vegetative growth","termid":"FYPO:0000784"},{"relation_name":"is_a","term_name":"abolished protein localization to actin cortical patch","termid":"FYPO:0006116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000138","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"abolished protein localization to actin cortical patch, with protein mislocalized to nucleus","synonyms":[{"name":"abolished protein localisation to actin cortical patch, with protein mislocalised to nucleus, during vegetative growth","type":"exact"},{"name":"abolished protein localization to actin cortical patch, with protein mislocalized to nucleus, during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to actin cortical patch, with protein mislocalized to nucleus, during vegetative growth","type":"exact"},{"name":"abolished protein localization to actin patch, with protein mislocalized to nucleus","type":"exact"},{"name":"protein localization to actin cortical patch abolished, with protein mislocalized to nucleus, during vegetative growth","type":"exact"}],"termid":"FYPO:0006795"}


id: PBO:0030625
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_tyrosine_phosphorylation","termid":"PBO:0030625"}


id: MONDO:0007851
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any keratoconus in which the cause of the disease is a mutation in the VSX1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"keratoconus","termid":"MONDO:0015486"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"keratoconus 1","secondary_identifiers":["OMIM:148300","MEDGEN:372103","MESH:C563649","UMLS:C1835677"],"synonyms":[{"name":"KTCN1","type":"related"},{"name":"VSX1 keratoconus (disease)","type":"exact"},{"name":"keratoconus (disease) caused by mutation in VSX1","type":"exact"},{"name":"keratoconus 1","type":"exact"},{"name":"keratoconus type 1","type":"exact"}],"termid":"MONDO:0007851","xrefs":{"Monarch":{"xref_id":"0007851"}}}


id: PBO:0046365
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ectonucleoside triphosphate diphosphohydrolase 2","termid":"PBO:0046365"}


id: PBO:0085084
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclear-enriched ubiquitin-like polyubiquitin-binding protein; required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle; involved in proteolysis; interacts with the proteasome; protein abundance increases in response to DNA replication stress","termid":"PBO:0085084"}


id: GO:0030567
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Increases the rate of proteolysis catalyzed by thrombin.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete thrombin activator activity (obsolete GO:0030567)","synonyms":[{"name":"prothrombin activator activity","type":"related"},{"name":"thrombin activator activity","type":"exact"}],"termid":"GO:0030567"}


id: GO:0062122
data:
  {"annotated_genes":["SJAG_03487"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[58192],"is_not":false,"summary":null,"term":"GO:0062122"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group to the lysine residue at position 37 of the histone H3 protein.","definition_xrefs":["PMID:30773398"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-lysine N-methyltransferase activity","termid":"GO:0016279"},{"relation_name":"is_a","term_name":"histone H3 methyltransferase activity","termid":"GO:0140938"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03487":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0008276","GO:0003674","GO:0016741","GO:0016740","GO:0003824","GO:0140096"],"is_obsolete":false,"name":"histone H3K37 methyltransferase activity","references_by_uniquename":{"GO_REF:0000002":null},"synonyms":[{"name":"histone H3K37 methylase activity","type":"exact"},{"name":"histone lysine N-methyltransferase activity (H3-K37 specific)","type":"exact"},{"name":"histone methyltransferase activity (H3-K37 specific)","type":"exact"},{"name":"histone-H3K37 methyltransferase activity","type":"exact"}],"termid":"GO:0062122","terms_by_termid":{"GO:0062122":null}}


id: MONDO:0018187
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete syndrome or malformation associated with head and neck malformations (obsolete MONDO:0015501)","termid":"MONDO:0015501"}],"gene_count":0,"genotype_count":0,"name":"obsolete hereditary syndromic Pierre Robin syndrome (obsolete MONDO:0018187)","secondary_identifiers":["Orphanet:363294"],"synonyms":[{"name":"genetic syndromic Pierre Robin syndrome","type":"exact"}],"termid":"MONDO:0018187","xrefs":{"Monarch":{"xref_id":"0018187"}}}


id: PBO:0061336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore complex interacting protein family member B14, pseudogene","termid":"PBO:0061336"}


id: PATO:0000631
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A positional quality inhering in a bearer by virtue of the bearer's being stretched out and lying at full length along the ground.","definition_xrefs":["thefreedictionary.com:thefreedictionary.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"position","termid":"PATO:0000140"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostrate","termid":"PATO:0000631"}


id: PBO:0059951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND2 pseudogene 37","termid":"PBO:0059951"}


id: PBO:0091488
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ErMes Regulator","termid":"PBO:0091488"}


id: GO:0005488
data:
  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id: PR:O14046
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A V-type proton ATPase 21 kDa proteolipid subunit that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01776","PANTHER:PTHR10263:SF1","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-type proton ATPase 20 kDa proteolipid subunit (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC2C4.13","secondary_identifiers":["UniProtKB:O14046"],"synonyms":[{"name":"Spom972h-ATP6V0B","type":"exact"},{"name":"V-ATPase 20 kDa proteolipid subunit (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"vacuolar proton pump 20 kDa proteolipid subunit (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O14046"}


id: RO:0002180
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.","direct_ancestors":[{"relation_name":"is_a","term_name":"has_part","termid":"BFO:0000051"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_component","termid":"RO:0002180"}


id: PBO:0071296
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L26 pseudogene 19","termid":"PBO:0071296"}


id: MONDO:0859181
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DEGCAGS syndrome","secondary_identifiers":["OMIM:619488","MEDGEN:1794177","UMLS:C5561967"],"termid":"MONDO:0859181","xrefs":{"Monarch":{"xref_id":"0859181"}}}


id: MONDO:0044630
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rere-related neurodevelopmental syndrome (obsolete MONDO:0044630)","termid":"MONDO:0044630","xrefs":{"Monarch":{"xref_id":"0044630"}}}


id: GO:0002064
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell development","termid":"GO:0048468"},{"relation_name":"part_of","term_name":"epithelial cell differentiation","termid":"GO:0030855"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"epithelial cell development","termid":"GO:0002064"}


id: FYPO:0008364
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H3-K9 methylation at silent mating-type cassette during vegetative growth","termid":"FYPO:0005865"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth","termid":"FYPO:0008364"}


id: PATO:0000993
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000993 relative viscosity (obsolete PATO:0000993)","termid":"PATO:0000993"}


id: PBO:0065672
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase receptor type T","termid":"PBO:0065672"}


id: PBO:0086762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; S288C contains an in-frame stop codon between ORFs YLR030W and YLR031W","termid":"PBO:0086762"}


id: GO:0048933
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.","definition_xrefs":["PMID:15018940"],"direct_ancestors":[{"relation_name":"is_a","term_name":"afferent axon development in lateral line nerve","termid":"GO:0048893"},{"relation_name":"part_of","term_name":"posterior lateral line nerve development","termid":"GO:0048918"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"afferent axon development in posterior lateral line nerve","termid":"GO:0048933"}


id: PBO:0085117
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA","termid":"PBO:0085117"}


id: PBO:0064405
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pancreatic lipase related protein 3","termid":"PBO:0064405"}


id: GO:0106372
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC.","definition_xrefs":["PMID:23723324","RHEA:67176"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674","GO:0016788"],"is_obsolete":false,"name":"primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity","termid":"GO:0106372"}


id: GO:0099504
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.","definition_xrefs":["PMID:15217342","GOC:aruk","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of localization in cell","termid":"GO:0051649"},{"relation_name":"is_a","term_name":"vesicle-mediated transport in synapse","termid":"GO:0099003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0016192","GO:0051179"],"is_obsolete":false,"name":"synaptic vesicle cycle","termid":"GO:0099504"}


id: GO:0032278
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of gonadotropin secretion","termid":"GO:0032276"},{"relation_name":"is_a","term_name":"positive regulation of hormone secretion","termid":"GO:0046887"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"positively_regulates","term_name":"gonadotropin secretion","termid":"GO:0032274"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0023052","GO:0006810"],"is_obsolete":false,"name":"positive regulation of gonadotropin secretion","synonyms":[{"name":"activation of gonadotropin secretion","type":"narrow"},{"name":"positive regulation of gonadotrophin secretion","type":"exact"},{"name":"stimulation of gonadotropin secretion","type":"narrow"},{"name":"up regulation of gonadotropin secretion","type":"exact"},{"name":"up-regulation of gonadotropin secretion","type":"exact"},{"name":"upregulation of gonadotropin secretion","type":"exact"}],"termid":"GO:0032278"}


id: GO:0071217
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to external biotic stimulus","termid":"GO:0043207"},{"relation_name":"is_a","term_name":"cellular response to biotic stimulus","termid":"GO:0071216"},{"relation_name":"is_a","term_name":"cellular response to external stimulus","termid":"GO:0071496"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to external biotic stimulus","termid":"GO:0071217"}


id: GO:0150190
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production.","definition_xrefs":["PMID:23729669","GOC:aruk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cytokine production","termid":"GO:0001818"},{"relation_name":"is_a","term_name":"regulation of interleukin-32 production","termid":"GO:0150189"},{"relation_name":"negatively_regulates","term_name":"interleukin-32 production","termid":"GO:0072637"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"negative regulation of interleukin-32 production","secondary_identifiers":["GO:0150193"],"synonyms":[{"name":"negative regulation of interleukin-32 biosynthetic process","type":"narrow"},{"name":"negative regulation of interleukin-32 secretion","type":"narrow"}],"termid":"GO:0150190"}


id: GO:0070501
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.","definition_xrefs":["GOC:mah","PMID:16689787"],"direct_ancestors":[{"relation_name":"is_a","term_name":"macromolecule biosynthetic process","termid":"GO:0009059"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"poly-gamma-glutamate biosynthetic process","synonyms":[{"name":"poly-gamma-glutamate anabolism","type":"exact"},{"name":"poly-gamma-glutamate biosynthesis","type":"exact"},{"name":"poly-gamma-glutamate formation","type":"exact"},{"name":"poly-gamma-glutamate synthesis","type":"exact"}],"termid":"GO:0070501"}


id: PBO:0034368
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-is_substance_that_treats","termid":"PBO:0034368"}


id: PBO:0077932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TPTE2 pseudogene 5","termid":"PBO:0077932"}


id: GO:0047537
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.","definition_xrefs":["MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN","EC:2.6.1.67"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transaminase activity","termid":"GO:0008483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016769"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016769"],"is_obsolete":false,"name":"2-aminohexanoate transaminase activity","secondary_identifiers":["RHEA:23600"],"synonyms":[{"name":"2-aminohexanoate aminotransferase activity","type":"exact"},{"name":"L-2-aminohexanoate:2-oxoglutarate aminotransferase activity","type":"related"},{"name":"leucine L-norleucine: 2-oxoglutarate aminotransferase activity","type":"related"},{"name":"norleucine (leucine) aminotransferase activity","type":"related"},{"name":"norleucine aminotransferase activity","type":"related"},{"name":"norleucine transaminase activity","type":"related"}],"termid":"GO:0047537"}


id: PBO:0000151
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5-oxoprolinase (ATP-hydrolizing) (predicted)","termid":"PBO:0000151"}


id: MONDO:0014346
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary mucosal leukokeratosis","termid":"MONDO:0015748"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"white sponge nevus 2","secondary_identifiers":["OMIM:615785","GARD:16012","DOID:0081288","MEDGEN:862758","UMLS:C4014321"],"synonyms":[{"name":"WHITE sponge NEVUS 2","type":"related"},{"name":"WSN2","type":"related"},{"name":"White sponge Nevus type 2","type":"exact"},{"name":"white sponge nevus 2","type":"exact"}],"termid":"MONDO:0014346","xrefs":{"Monarch":{"xref_id":"0014346"}}}


id: PBO:0071495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L32 pseudogene 36","termid":"PBO:0071495"}


id: PBO:0003276
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.5.4.9","termid":"PBO:0003276"}


id: MONDO:0009978
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Retinal degeneration-nanophthalmos-glaucoma syndrome is characterized by progressive pigmentary retinal degeneration (with nyctalopia and visual field restriction), cystic macular degeneration and angle closure glaucoma. It has been described in seven members of one family. Patients also have hyperopia and nanophthalmos. The mode of transmission is autosomal recessive.","definition_xrefs":["Orphanet:1574"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete non-syndromic developmental defect of the eye (obsolete MONDO:0015217)","termid":"MONDO:0015217"},{"relation_name":"is_a","term_name":"inherited retinal dystrophy","termid":"MONDO:0019118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"retinal degeneration-nanophthalmos-glaucoma syndrome","secondary_identifiers":["MEDGEN:444153","SCTID:723503006","UMLS:C2931831","MESH:C538364","OMIM:267760","GARD:395","ICD10CM:H35.5"],"synonyms":[{"name":"MacKay Shek Carr syndrome","type":"related"},{"name":"Mackay-Shek-Carr syndrome","type":"exact"},{"name":"retinal degeneration with nanophthalmos, cystic macular degeneration, and angle closure glaucoma","type":"related"},{"name":"retinal degeneration, nanophthalmos, glaucoma","type":"related"}],"termid":"MONDO:0009978","xrefs":{"Monarch":{"xref_id":"0009978"}}}


id: GO:0003057
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.","definition_xrefs":["GOC:mtg_cardio","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of the force of heart contraction","termid":"GO:0002026"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of the force of heart contraction by chemical signal","synonyms":[{"name":"chemical cardiac inotropy","type":"exact"},{"name":"regulation of the force of heart muscle contraction by chemical signal","type":"related"}],"termid":"GO:0003057"}


id: PBO:0078724
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Leu (anticodon TAG) 4-1","termid":"PBO:0078724"}


id: PBO:0089129
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Hsp70 nucleotide exchange factor Fes1","termid":"PBO:0089129"}


id: PBO:0084408
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant","termid":"PBO:0084408"}


id: PBO:0048153
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"forty-two-three domain containing 1","termid":"PBO:0048153"}


id: GO:0017121
data:
  {"annotated_genes":["SJAG_01470"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73549],"is_not":false,"summary":null,"term":"GO:0017121"}]},"cv_name":"biological_process","definition":"The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).","definition_xrefs":["PMID:20302864","GOC:cjm","PMID:20043909"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane organization","termid":"GO:0007009"},{"relation_name":"is_a","term_name":"phospholipid translocation","termid":"GO:0045332"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01470":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150","GO:0061024"],"is_obsolete":false,"name":"plasma membrane phospholipid scrambling","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"PL scrambling","type":"exact"},{"name":"phospholipid scrambling","type":"related"}],"termid":"GO:0017121","terms_by_termid":{"GO:0017121":null}}


id: GO:1901129
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of gentamycin.","definition_xrefs":["UniPathway:UPA00967","GOC:yaf","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoglycoside antibiotic catabolic process","termid":"GO:0030649"},{"relation_name":"is_a","term_name":"polyol catabolic process","termid":"GO:0046174"},{"relation_name":"is_a","term_name":"gentamycin metabolic process","termid":"GO:1901128"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"gentamycin catabolic process","synonyms":[{"name":"gentamycin breakdown","type":"exact"},{"name":"gentamycin catabolism","type":"exact"},{"name":"gentamycin degradation","type":"exact"}],"termid":"GO:1901129"}


id: GO:0006031
data:
  {"annotated_genes":["SJAG_00978","SJAG_03723","SJAG_00442","SJAG_04728","SJAG_02845","SJAG_04868"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71395,72321,74627,74803,78692,110360],"is_not":false,"summary":null,"term":"GO:0006031"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aminoglycan biosynthetic process","termid":"GO:0006023"},{"relation_name":"is_a","term_name":"chitin metabolic process","termid":"GO:0006030"},{"relation_name":"is_a","term_name":"glucosamine-containing compound biosynthetic process","termid":"GO:1901073"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00442":null,"SJAG_00978":null,"SJAG_02845":null,"SJAG_03723":null,"SJAG_04728":null,"SJAG_04868":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chitin biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:PWY-6981"],"synonyms":[{"name":"beta-1,4-linked N-acetylglucosamine biosynthesis","type":"exact"},{"name":"beta-1,4-linked N-acetylglucosamine biosynthetic process","type":"exact"},{"name":"chitin anabolism","type":"exact"},{"name":"chitin biosynthesis","type":"exact"},{"name":"chitin formation","type":"exact"},{"name":"chitin synthesis","type":"exact"}],"termid":"GO:0006031","terms_by_termid":{"GO:0006031":null}}


id: PBO:0081617
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 546","termid":"PBO:0081617"}


id: PBO:0041567
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 20 open reading frame 141","termid":"PBO:0041567"}


id: GO:1901218
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of holin activity.","definition_xrefs":["GOC:TermGenie","GOC:bm"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of holin activity (obsolete GO:1901218)","synonyms":[{"name":"antiholin activity","type":"exact"},{"name":"down regulation of holin activity","type":"exact"},{"name":"down-regulation of holin activity","type":"exact"},{"name":"downregulation of holin activity","type":"exact"},{"name":"inhibition of holin activity","type":"narrow"},{"name":"phage antiholin","type":"narrow"}],"termid":"GO:1901218"}


id: PBO:0001619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome component beta 5","termid":"PBO:0001619"}


id: GO:1902738
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.","definition_xrefs":["GOC:TermGenie","PMID:8662546","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of chondrocyte differentiation","termid":"GO:0032330"},{"relation_name":"is_a","term_name":"regulation of bone development","termid":"GO:1903010"},{"relation_name":"is_a","term_name":"regulation of animal organ morphogenesis","termid":"GO:2000027"},{"relation_name":"regulates","term_name":"chondrocyte differentiation involved in endochondral bone morphogenesis","termid":"GO:0003413"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of chondrocyte differentiation involved in endochondral bone morphogenesis","termid":"GO:1902738"}


id: FYPO:0004082
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during mitosis.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein phosphorylation during vegetative growth","termid":"FYPO:0000776"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal protein phosphorylation during mitosis","synonyms":[{"name":"normal protein phosphorylation during mitosis during vegetative growth","type":"exact"},{"name":"normal protein phosphorylation during mitotic M phase","type":"related"},{"name":"normal protein phosphorylation during mitotic nuclear division","type":"exact"}],"termid":"FYPO:0004082"}


id: MONDO:0044660
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"female reproductive system disorder","termid":"MONDO:0002263"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"menstrual cycle-dependent periodic fever","secondary_identifiers":["MEDGEN:766332","OMIM:614674","GARD:22017","Orphanet:498251","UMLS:C3553418"],"synonyms":[{"name":"luteal-phase-dependent febrile episode","type":"exact"},{"name":"luteal-phase-dependent periodic fever","type":"exact"},{"name":"menstrual cycle-dependent febrile episode","type":"exact"},{"name":"periodic fever, menstrual cycle dependent","type":"exact"},{"name":"periodic fever, menstrual cycle-dependent","type":"exact"}],"termid":"MONDO:0044660","xrefs":{"Monarch":{"xref_id":"0044660"}}}


id: PBO:0077549
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 256 pseudogene 2","termid":"PBO:0077549"}


id: PBO:0072319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S26 pseudogene 5","termid":"PBO:0072319"}


id: GO:0034581
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 4-methyloct-2-enoyl-CoA hydratase activity (obsolete GO:0034581)","termid":"GO:0034581"}


id: GO:0018713
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.","definition_xrefs":["UM-BBD_reactionID:r0197"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, transferring groups other than amino-acyl groups","termid":"GO:0016747"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016746","GO:0003674","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"3-ketopimelyl-CoA thiolase activity","secondary_identifiers":["MetaCyc:RXN-8032"],"termid":"GO:0018713"}


id: GO:0050767
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of nervous system development","termid":"GO:0051960"},{"relation_name":"is_a","term_name":"regulation of cell development","termid":"GO:0060284"},{"relation_name":"regulates","term_name":"neurogenesis","termid":"GO:0022008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of neurogenesis","termid":"GO:0050767"}


id: GO:0140573
data:
  {"annotated_genes":["SJAG_00302"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[119907],"is_not":false,"summary":null,"term":"GO:0140573"}]},"cv_name":"cellular_component","definition":"A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures.","definition_xrefs":["PMID:33155135"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleosome","termid":"GO:0000786"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00302":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005694"}],"interesting_parent_ids":["GO:0005694","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"histone H3-containing nucleosome","references_by_uniquename":{"PMID:24184107":null},"synonyms":[{"name":"histone H3 containing nucleosome","type":"exact"}],"termid":"GO:0140573","terms_by_termid":{"GO:0140573":null}}


id: GO:2000451
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of T cell extravasation","termid":"GO:2000409"},{"relation_name":"is_a","term_name":"regulation of CD8-positive, alpha-beta T cell extravasation","termid":"GO:2000449"},{"relation_name":"positively_regulates","term_name":"CD8-positive, alpha-beta T cell extravasation","termid":"GO:0035697"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of CD8-positive, alpha-beta T cell extravasation","termid":"GO:2000451"}


id: PBO:0083097
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA damage-responsive protein; expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS; protein abundance increases in response to DNA replication stress","termid":"PBO:0083097"}


id: SO:0000423
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The R segment of the long terminal repeats.","direct_ancestors":[{"relation_name":"is_a","term_name":"LTR_component","termid":"SO:0000848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"R_LTR_region","synonyms":[{"name":"R LTR region","type":"exact"},{"name":"R long terminal repeat region","type":"exact"}],"termid":"SO:0000423"}


id: GO:0070449
data:
  {"annotated_genes":["SJAG_03211","SJAG_00540"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[63915,76857],"is_not":false,"summary":null,"term":"GO:0070449"}]},"cv_name":"cellular_component","definition":"A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.","definition_xrefs":["PMID:12676794"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription elongation factor complex","termid":"GO:0008023"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00540":null,"SJAG_03211":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005654"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005575","GO:0005654","GO:0005634","GO:0032991"],"is_obsolete":false,"name":"elongin complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"synonyms":[{"name":"elongin (SIII) complex","type":"exact"},{"name":"transcription elongation factor SIII complex","type":"exact"},{"name":"transcription factor B (SIII) complex","type":"exact"}],"termid":"GO:0070449","terms_by_termid":{"GO:0070449":null}}


id: PBO:0040825
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bridging integrator 3","termid":"PBO:0040825"}


id: GO:2001264
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding.","definition_xrefs":["GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of C-C chemokine binding (obsolete GO:2001264)","termid":"GO:2001264"}


id: MONDO:0013702
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive non-syndromic intellectual disability in which the cause of the disease is a mutation in the LINS1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0037792","MONDO:0006025"],"is_obsolete":false,"name":"intellectual disability, autosomal recessive 27","secondary_identifiers":["UMLS:C3280538","MEDGEN:482168","OMIM:614340","DOID:0081193","GARD:22555"],"synonyms":[{"name":"LINS1 autosomal recessive non-syndromic intellectual disability","type":"exact"},{"name":"MRT27","type":"related"},{"name":"autosomal recessive non-syndromic intellectual disability caused by mutation in LINS1","type":"exact"},{"name":"intellectual developmental disorder, autosomal recessive 27","type":"exact"},{"name":"intellectual disability, autosomal recessive 27","type":"exact"},{"name":"intellectual disability, autosomal recessive type 27","type":"exact"},{"name":"mental retardation, autosomal recessive 27","type":"related"},{"name":"mental retardation, autosomal recessive type 27","type":"exact"}],"termid":"MONDO:0013702","xrefs":{"Monarch":{"xref_id":"0013702"}}}


id: PBO:0051947
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol-trisphosphate 3-kinase A","termid":"PBO:0051947"}


id: MONDO:0020001
data:
  {"annotated_genes":["SJAG_01370","SJAG_01065","SJAG_03847"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86482],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0100104"},{"annotations":[86536],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009670"},{"annotations":[87173],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054565"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system disorder","termid":"MONDO:0005087"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01065":null,"SJAG_01370":null,"SJAG_03847":null},"genotype_count":0,"is_obsolete":false,"name":"respiratory or thoracic malformation","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1842800","GARD:19385","Orphanet:97957","UMLS:C5681559"],"termid":"MONDO:0020001","terms_by_termid":{"MONDO:0009670":null,"MONDO:0054565":null,"MONDO:0100104":null},"xrefs":{"Monarch":{"xref_id":"0020001"}}}


id: PBO:0042649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromodomain Y like","termid":"PBO:0042649"}


id: GO:0004289
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Was not defined before being made obsolete.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete subtilase activity (obsolete GO:0004289)","synonyms":[{"name":"subtilase activity","type":"exact"}],"termid":"GO:0004289"}


id: GO:0004957
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prostaglandin receptor activity","termid":"GO:0004955"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"prostaglandin E receptor activity","synonyms":[{"name":"PGE receptor activity","type":"related"},{"name":"PGE(2) receptor activity","type":"exact"}],"termid":"GO:0004957"}


id: GO:0009070
data:
  {"annotated_genes":["SJAG_00582","SJAG_03152","SJAG_01880","SJAG_02972","SJAG_00234","SJAG_03914","SJAG_01766","SJAG_02450","SJAG_02791","SJAG_04305","SJAG_04449","SJAG_00881","SJAG_02313"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73035,76507,77865],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006535"},{"annotations":[110818],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019343"},{"annotations":[72344],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006545"},{"annotations":[72496,73736],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019264"},{"annotations":[71477,116085,74002],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009090"},{"annotations":[110819],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071269"},{"annotations":[80049,61081,117209],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006564"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"serine family amino acid metabolic process","termid":"GO:0009069"},{"relation_name":"is_a","term_name":"alpha-amino acid biosynthetic process","termid":"GO:1901607"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00234":null,"SJAG_00582":null,"SJAG_00881":null,"SJAG_01766":null,"SJAG_01880":null,"SJAG_02313":null,"SJAG_02450":null,"SJAG_02791":null,"SJAG_02972":null,"SJAG_03152":null,"SJAG_03914":null,"SJAG_04305":null,"SJAG_04449":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0006520","GO:0008150"],"is_obsolete":false,"name":"serine family amino acid biosynthetic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"serine family amino acid anabolism","type":"exact"},{"name":"serine family amino acid biosynthesis","type":"exact"},{"name":"serine family amino acid formation","type":"exact"},{"name":"serine family amino acid synthesis","type":"exact"}],"termid":"GO:0009070","terms_by_termid":{"GO:0006535":null,"GO:0006545":null,"GO:0006564":null,"GO:0009090":null,"GO:0019264":null,"GO:0019343":null,"GO:0071269":null}}


id: MONDO:0859352
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 79","secondary_identifiers":["UMLS:C5774290","DOID:0070578","MEDGEN:1824063","OMIM:620196"],"termid":"MONDO:0859352","xrefs":{"Monarch":{"xref_id":"0859352"}}}


id: PBO:0056548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"melanin concentrating hormone receptor 2","termid":"PBO:0056548"}


id: GO:0080156
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.","definition_xrefs":["PMID:20566637"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA modification","termid":"GO:0016556"},{"relation_name":"is_a","term_name":"mitochondrial RNA modification","termid":"GO:1900864"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016071"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0016071"],"is_obsolete":false,"name":"mitochondrial mRNA modification","synonyms":[{"name":"mitochondrial RNA editing","type":"broad"},{"name":"mitochondrial mRNA editing","type":"narrow"}],"termid":"GO:0080156"}


id: PBO:0013774
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mst2 histone acetytransferase acytyltransferase complex, predicted phosphoric monoester hydrolase Ptf1","termid":"PBO:0013774"}


id: GO:0004042
data:
  {"annotated_genes":["SJAG_00695","SJAG_01592"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[65493,72544],"is_not":false,"summary":null,"term":"GO:0004042"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H+.","definition_xrefs":["RHEA:24292"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-amino-acid N-acetyltransferase activity","termid":"GO:0140085"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00695":null,"SJAG_01592":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016746","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"L-glutamate N-acetyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null},"secondary_identifiers":["Reactome:R-HSA-70542","MetaCyc:N-ACETYLTRANSFER-RXN","KEGG_REACTION:R00259"],"synonyms":[{"name":"AGAS","type":"related"},{"name":"N-acetylglutamate synthase activity","type":"broad"},{"name":"acetyl-CoA:L-glutamate N-acetyltransferase activity","type":"exact"},{"name":"acetylglutamate acetylglutamate synthetase activity","type":"related"},{"name":"amino acid acetyltransferase activity","type":"related"},{"name":"amino-acid N-acetyltransferase activity","type":"broad"}],"termid":"GO:0004042","terms_by_termid":{"GO:0004042":null}}


id: GO:0043718
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD+ = 2-formylglutarate + H+ + NADH.","definition_xrefs":["RHEA:15505","EC:1.1.1.291"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"2-hydroxymethylglutarate dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R07985","Wikipedia:2-hydroxymethylglutarate_dehydrogenase","MetaCyc:1.1.1.291-RXN"],"synonyms":[{"name":"(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity","type":"related"},{"name":"HgD","type":"exact"}],"termid":"GO:0043718"}


id: GO:0035929
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated release of any steroid that acts as a hormone into the circulatory system.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endocrine hormone secretion","termid":"GO:0060986"},{"relation_name":"is_a","term_name":"lipid export from cell","termid":"GO:0140353"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0023052","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"steroid hormone secretion","termid":"GO:0035929"}


id: PBO:0081679
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 600","termid":"PBO:0081679"}


id: MONDO:0040500
data:
  {"annotated_genes":["SJAG_04119"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85440],"is_not":false,"summary":null,"term":"MONDO:0040500"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"inherited lipid metabolism disorder","termid":"MONDO:0002525"},{"relation_name":"is_a","term_name":"congenital disorder of glycosylation","termid":"MONDO:0015286"},{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"},{"relation_name":"is_a","term_name":"disorder of GPI anchor biosynthesis","termid":"MONDO:0024321"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04119":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0006025","MONDO:0002525","MONDO:0024322","MONDO:0037792","MONDO:0002320"],"is_obsolete":false,"name":"glycosylphosphatidylinositol biosynthesis defect 16","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:22577","MEDGEN:1628197","UMLS:C4540521","OMIM:617816","DOID:0081223"],"synonyms":[{"name":"GPIBD16","type":"related"},{"name":"glycosylphosphatidylinositol biosynthesis defect 16","type":"exact"},{"name":"intellectual disability, autosomal recessive 62","type":"related"},{"name":"mental retardation, autosomal recessive 62","type":"related"}],"termid":"MONDO:0040500","terms_by_termid":{"MONDO:0040500":null},"xrefs":{"Monarch":{"xref_id":"0040500"}}}


id: PBO:0000331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase Dbp10 (predicted)","termid":"PBO:0000331"}


id: PBO:0089476
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytoplasmic phenylalanine-tRNA ligase beta subunit Frs1","termid":"PBO:0089476"}


id: GO:0004486
data:
  {"annotated_genes":["SJAG_00106","SJAG_04156","SJAG_01126"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70778],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004487"},{"annotations":[57720,76090,76922],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004488"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+.","definition_xrefs":["GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00106":null,"SJAG_01126":null,"SJAG_04156":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-200644","Reactome:R-HSA-200718"],"synonyms":[{"name":"5,10-methylene-THF dehydrogenase activity","type":"exact"},{"name":"N5,N10-methylenetetrahydrofolate dehydrogenase activity","type":"related"}],"termid":"GO:0004486","terms_by_termid":{"GO:0004487":null,"GO:0004488":null}}


id: FYPO:0003451
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the nucleus is abolished during anaphase of the second meiotic nuclear division.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to nucleus","termid":"FYPO:0003450"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to nucleus during meiotic anaphase II","synonyms":[{"name":"abolished protein localisation to nucleus during meiotic anaphase II","type":"exact"},{"name":"abolished protein localization to nucleus during anaphase II","type":"exact"},{"name":"nuclear exclusion during meiotic anaphase II","type":"related"},{"name":"nuclear protein exclusion during meiotic anaphase II","type":"related"},{"name":"protein localization to nucleus abolished during meiotic anaphase II","type":"exact"}],"termid":"FYPO:0003451"}


id: MONDO:0016141
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"sarcoglycanopathy","termid":"MONDO:0016140"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"qualitative or quantitative defects of alpha-sarcoglycan","secondary_identifiers":["Orphanet:207060","GARD:20390","MEDGEN:1842296","UMLS:C5680808"],"synonyms":[{"name":"alpha-sarcoglycanopathy","type":"exact"}],"termid":"MONDO:0016141","xrefs":{"Monarch":{"xref_id":"0016141"}}}


id: PBO:0071101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 103","termid":"PBO:0071101"}


id: GO:0072095
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of developmental growth","termid":"GO:0048638"},{"relation_name":"regulates","term_name":"branch elongation involved in ureteric bud branching","termid":"GO:0060681"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of branch elongation involved in ureteric bud branching","termid":"GO:0072095"}


id: FYPO:0008221
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which acetylation of lysine at position 56 of histone H3 is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:27268234"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H3-K56 acetylation during vegetative growth","termid":"FYPO:0008160"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000002","FYPO:0000257","FYPO:0001320"],"is_obsolete":false,"name":"normal histone H3-K56 acetylation during mitotic G2/M phase","termid":"FYPO:0008221"}


id: PR:O42943
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ATP-binding cassette sub-family F member 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03209","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized ABC transporter ATP-binding protein C16H5.08c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16H5.08c","secondary_identifiers":["UniProtKB:O42943"],"synonyms":[{"name":"Spom972h-ABCF2","type":"exact"}],"termid":"PR:O42943"}


id: GO:0035920
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.","definition_xrefs":["PMID:20920515","GOC:fj","ISBN:0815340729","GOC:bf"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of high voltage-gated calcium channel activity in another organism (obsolete GO:0035920)","synonyms":[{"name":"down-regulation of high voltage-gated calcium channel activity in other organism","type":"exact"},{"name":"downregulation of high voltage-gated calcium channel activity in other organism","type":"exact"},{"name":"inhibition of high voltage-gated calcium channel activity in other organism","type":"narrow"},{"name":"negative regulation of high voltage gated calcium channel activity in other organism","type":"exact"},{"name":"negative regulation of high voltage-dependent calcium channel activity in other organism","type":"exact"},{"name":"negative regulation of high voltage-gated calcium channel activity in other organism","type":"exact"}],"termid":"GO:0035920"}


id: MONDO:0012072
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial partial lipodystrophy, Kobberling type, is a very rare form of familial partial lipodystrophy (FPLD) of unknown etiology characterized by lipoatrophy that is confined to the limbs and a normal or increased fat distribution of the face, neck, and trunk. Arterial hypertension and diabetes have also been associated. Inheritance is thought to be autosomal dominant.","definition_xrefs":["Orphanet:79084"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial partial lipodystrophy","termid":"MONDO:0020088"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066"],"is_obsolete":false,"name":"familial partial lipodystrophy, Kobberling type","secondary_identifiers":["OMIM:608600","MEDGEN:318591","UMLS:C1720859","DOID:0070207","GARD:12598","SCTID:725035001"],"synonyms":[{"name":"FPLD1","type":"exact"},{"name":"familial partial lipodystrophy type 1","type":"exact"},{"name":"familial partial lipodystrophy type Köbberling","type":"related"},{"name":"familial partial lipodystrophy, Köbberling type","type":"related"},{"name":"lipodystrophy, familial partial, Kobberling type","type":"related"},{"name":"lipodystrophy, familial partial, type 1","type":"related"}],"termid":"MONDO:0012072","xrefs":{"Monarch":{"xref_id":"0012072"}}}


id: PBO:0068393
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein 213","termid":"PBO:0068393"}


id: PBO:0109840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase feature property types","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"canto_allele_systematic_id","termid":"PBO:0109840"}


id: PBO:0049618
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H3 histone pseudogene 21","termid":"PBO:0049618"}


id: GO:0120270
data:
  {"annotated_genes":["SJAG_02723","SJAG_03883"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90126],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120271"},{"annotations":[106975],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120272"}]},"cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.","definition_xrefs":["PMID:24920274","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mRNA catabolic process","termid":"GO:0061013"},{"relation_name":"regulates","term_name":"nuclear mRNA surveillance of meiosis-specific transcripts","termid":"GO:0033621"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02723":null,"SJAG_03883":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0016071"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0016071","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of nuclear mRNA surveillance of meiosis-specific transcripts","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts","type":"exact"}],"termid":"GO:0120270","terms_by_termid":{"GO:0120271":null,"GO:0120272":null}}


id: GO:0044146
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.","definition_xrefs":["GOC:jl","GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of growth of symbiont involved in interaction with host (obsolete GO:0044146)","synonyms":[{"name":"negative regulation of growth of symbiont during interaction with host","type":"related"}],"termid":"GO:0044146"}


id: MONDO:0020697
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A lung carcinoma arising within the bronchi or bronchial tubes. It is characterized by the presence of myoepithelial cells, spindle cells, clear cells, and duct-forming epithelial cells. Surgical resection may be curative.","definition_xrefs":["NCIT:C45545"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial-myoepithelial carcinoma","termid":"MONDO:0003389"},{"relation_name":"is_a","term_name":"lung carcinoma","termid":"MONDO:0005138"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"lung epithelial-myoepithelial carcinoma","secondary_identifiers":["MEDGEN:353868","UMLS:C1708770"],"synonyms":[{"name":"lung epithelial-myoepithelial cancer","type":"exact"},{"name":"lung epithelial-myoepithelial carcinoma","type":"exact"}],"termid":"MONDO:0020697","xrefs":{"Monarch":{"xref_id":"0020697"}}}


id: GO:0035860
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor.","definition_xrefs":["PMID:29245123","GOC:yaf","PMID:12953054"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell surface receptor protein tyrosine kinase signaling pathway","termid":"GO:0007169"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"glial cell-derived neurotrophic factor receptor signaling pathway","synonyms":[{"name":"GDNF receptor signaling pathway","type":"exact"},{"name":"glial cell derived neurotrophic factor receptor signaling pathway","type":"exact"},{"name":"glial cell line-derived neurotrophic factor receptor signalling pathway","type":"exact"},{"name":"glial cell-derived neurotrophic factor receptor signalling pathway","type":"exact"}],"termid":"GO:0035860"}


id: PBO:0055849
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LDL receptor related protein 1","termid":"PBO:0055849"}


id: FYPO:0006386
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a protein that normally localizes to a compact region at the tip of a shmoo, or mating projection, is more dispersed than normal.","definition_xrefs":["PomBase:mah","PMID:19627505"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to shmoo tip","termid":"FYPO:0004802"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"protein abnormally dispersed at shmoo tip","synonyms":[{"name":"abnormally dispersed protein localization at shmoo tip","type":"exact"},{"name":"protein abnormally dispersed at mating projection tip","type":"exact"},{"name":"protein abnormally dispersed at shmoo projection","type":"related"}],"termid":"FYPO:0006386"}


id: GO:1904244
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:12771515"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein secretion","termid":"GO:0050714"},{"relation_name":"is_a","term_name":"regulation of pancreatic trypsinogen secretion","termid":"GO:1904242"},{"relation_name":"positively_regulates","term_name":"pancreatic trypsinogen secretion","termid":"GO:1990747"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of pancreatic trypsinogen secretion","synonyms":[{"name":"activation of pancreatic trypsinogen release","type":"narrow"},{"name":"activation of pancreatic trypsinogen secretion","type":"narrow"},{"name":"positive regulation of pancreatic trypsinogen release","type":"exact"},{"name":"up regulation of pancreatic trypsinogen release","type":"exact"},{"name":"up regulation of pancreatic trypsinogen secretion","type":"exact"},{"name":"up-regulation of pancreatic trypsinogen release","type":"exact"},{"name":"up-regulation of pancreatic trypsinogen secretion","type":"exact"},{"name":"upregulation of pancreatic trypsinogen release","type":"exact"},{"name":"upregulation of pancreatic trypsinogen secretion","type":"exact"}],"termid":"GO:1904244"}


id: PBO:0078477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ile (anticodon AAT) 1-1","termid":"PBO:0078477"}


id: PBO:0057058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR142 host genes","termid":"PBO:0057058"}


id: GO:0044636
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism.","definition_xrefs":["PMID:20837040","GOC:jl","GOC:fj"],"gene_count":0,"genotype_count":0,"name":"obsolete envenomation resulting in modulation of complement activation, classical pathway in another organism (obsolete GO:0044636)","synonyms":[{"name":"envenomation resulting in modulation of complement activation, classical pathway in other organism","type":"exact"}],"termid":"GO:0044636"}


id: GO:0050852
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antigen receptor-mediated signaling pathway","termid":"GO:0050851"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"T cell receptor signaling pathway","secondary_identifiers":["Reactome:R-HSA-202403"],"synonyms":[{"name":"T lymphocyte receptor signaling pathway","type":"exact"},{"name":"T lymphocyte receptor signalling pathway","type":"exact"},{"name":"T-cell receptor signaling pathway","type":"exact"},{"name":"T-cell receptor signalling pathway","type":"exact"},{"name":"T-lymphocyte receptor signaling pathway","type":"exact"},{"name":"T-lymphocyte receptor signalling pathway","type":"exact"},{"name":"TCR signaling pathway","type":"exact"}],"termid":"GO:0050852"}


id: GO:0009034
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-tryptophan + H2O = indole + NH4 + pyruvate.","definition_xrefs":["RHEA:19553"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-carbon lyase activity","termid":"GO:0016830"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016829","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"tryptophanase activity","secondary_identifiers":["EC:4.1.99.1","KEGG_REACTION:R00673","MetaCyc:TRYPTOPHAN-RXN"],"synonyms":[{"name":"L-tryptophan indole-lyase (deaminating) activity","type":"related"},{"name":"L-tryptophan indole-lyase (deaminating; pyruvate forming) activity","type":"related"},{"name":"L-tryptophan indole-lyase activity","type":"related"},{"name":"L-tryptophanase activity","type":"related"},{"name":"TNase activity","type":"related"},{"name":"tryptophan catabolic process, using tryptophanase","type":"related"},{"name":"tryptophan catabolism, using tryptophanase","type":"related"}],"termid":"GO:0009034"}


id: GO:1900798
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of cordyol C.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catechol-containing compound catabolic process","termid":"GO:0019614"},{"relation_name":"is_a","term_name":"secondary metabolite catabolic process","termid":"GO:0090487"},{"relation_name":"is_a","term_name":"cordyol C metabolic process","termid":"GO:1900797"},{"relation_name":"is_a","term_name":"ether catabolic process","termid":"GO:1901502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0019748"],"is_obsolete":false,"name":"cordyol C catabolic process","synonyms":[{"name":"cordyol C breakdown","type":"exact"},{"name":"cordyol C catabolism","type":"exact"},{"name":"cordyol C degradation","type":"exact"}],"termid":"GO:1900798"}


id: GO:0035642
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to the arginine residue at position 17 of histone H3.","definition_xrefs":["GOC:sp","PMID:11341840"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-arginine N-methyltransferase activity","termid":"GO:0016274"},{"relation_name":"is_a","term_name":"histone H3 methyltransferase activity","termid":"GO:0140938"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016740","GO:0140096","GO:0016741","GO:0008276"],"is_obsolete":false,"name":"histone H3R17 methyltransferase activity","synonyms":[{"name":"histone methylase activity (H3-R17 specific)","type":"exact"},{"name":"histone methyltransferase activity (H3-R17 specific)","type":"exact"},{"name":"histone-H3R17 methyltransferase activity","type":"exact"},{"name":"histone-arginine N-methyltransferase activity (H3-R17 specific)","type":"exact"}],"termid":"GO:0035642"}


id: PBO:0077184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"toll like receptor 8","termid":"PBO:0077184"}


id: GO:0039657
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont inhibits or disrupts expression of genes in its host. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["VZ:1582"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host gene expression","termid":"GO:0039656"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host gene expression","synonyms":[{"name":"host gene expression shutoff","type":"exact"},{"name":"host gene expression shutoff by virus","type":"narrow"},{"name":"suppression by virus of host gene expression","type":"narrow"}],"termid":"GO:0039657"}


id: MONDO:0004814
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete vascular skin disease (obsolete MONDO:0004814)","termid":"MONDO:0004814","xrefs":{"Monarch":{"xref_id":"0004814"}}}


id: PBO:0029741
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-spheroid_cell_during_nitrogen_starvation","termid":"PBO:0029741"}


id: PBO:0027308
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_UV-damage_excision_repair","termid":"PBO:0027308"}


id: GO:0140825
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O.","definition_xrefs":["RHEA:56136","PMID:19339248"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peroxidase activity","termid":"GO:0004601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"lactoperoxidase activity","secondary_identifiers":["EC:1.11.1.7","MetaCyc:PEROXID-RXN"],"synonyms":[{"name":"peroxidase activity","type":"broad"}],"termid":"GO:0140825"}


id: PBO:0082560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ceramide synthase component; involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p; LAC1 has a paralog, LAG1, that arose from the whole genome duplication","termid":"PBO:0082560"}


id: MONDO:0014455
data:
  {"annotated_genes":["SJAG_04285"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87215],"is_not":false,"summary":null,"term":"MONDO:0014455"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary endocrine growth disease","termid":"MONDO:0015514"},{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"},{"relation_name":"is_a","term_name":"spondyloepiphyseal dysplasia","termid":"MONDO:0016761"},{"relation_name":"is_a","term_name":"hereditary peripheral neuropathy","termid":"MONDO:0020127"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04285":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005244","MONDO:0005497","MONDO:0005066"],"is_obsolete":false,"name":"cataract-growth hormone deficiency-sensory neuropathy-sensorineural hearing loss-skeletal dysplasia syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:436174","GARD:17727","OMIM:616007","MEDGEN:863379","UMLS:C4014942"],"synonyms":[{"name":"CAGSSS","type":"exact"},{"name":"cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia","type":"related"}],"termid":"MONDO:0014455","terms_by_termid":{"MONDO:0014455":null},"xrefs":{"Monarch":{"xref_id":"0014455"}}}


id: PBO:0031140
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_actomyosin_contractile_ring_actin_filament_organization","termid":"PBO:0031140"}


id: PBO:0056037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"latent transforming growth factor beta binding protein 2","termid":"PBO:0056037"}


id: GO:0102428
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose = kaempferol-3-gentiobioside + UDP.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete kaempferol-3-O-glucoside 1,6-glucosyltransferase activity (obsolete GO:0102428)","termid":"GO:0102428"}


id: GO:2000471
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell migration","termid":"GO:0030334"},{"relation_name":"regulates","term_name":"hematopoietic stem cell migration","termid":"GO:0035701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of hematopoietic stem cell migration","synonyms":[{"name":"regulation of hemopoietic stem cell migration","type":"exact"}],"termid":"GO:2000471"}


id: PBO:0053352
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 243","termid":"PBO:0053352"}


id: MONDO:0100563
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of alpha thalessemia spectrum that is caused by an inherited multiallelic modification in an individual.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha thalassemia spectrum","termid":"MONDO:0011399"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"digenic alpha thalassemia spectrum","termid":"MONDO:0100563","xrefs":{"Monarch":{"xref_id":"0100563"}}}


id: PBO:0073096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"succinate dehydrogenase complex subunit D","termid":"PBO:0073096"}


id: MONDO:0008134
data:
  {"annotated_genes":["SJAG_02656"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86124],"is_not":false,"summary":null,"term":"MONDO:0008134"}]},"cv_name":"mondo","definition":"One of the most common forms of hereditary optic neuropathy characterized by progressive bilateral visual loss during the first decade of life, associated with optic disk pallor, visual field and color vision defects.","definition_xrefs":["Orphanet:98673"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"},{"relation_name":"is_a","term_name":"autosomal dominant optic atrophy","termid":"MONDO:0020250"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02656":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005066","MONDO:0005559","MONDO:0000426","MONDO:0004069"],"is_obsolete":false,"name":"autosomal dominant optic atrophy, classic form","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:165500","MEDGEN:137902","SCTID:717336005","UMLS:C0338508","DOID:0111441","GARD:9890"],"synonyms":[{"name":"Kjer optic atrophy","type":"exact"},{"name":"Kjer-type optic atrophy","type":"related"},{"name":"OAK","type":"related"},{"name":"OPA1","type":"related"},{"name":"autosomal dominant optic atrophy, Kjer type","type":"exact"},{"name":"optic atrophy 1","type":"related"},{"name":"optic atrophy type 1","type":"exact"},{"name":"optic atrophy, Kjer type","type":"related"},{"name":"optic atrophy, juvenile","type":"related"}],"termid":"MONDO:0008134","terms_by_termid":{"MONDO:0008134":null},"xrefs":{"Monarch":{"xref_id":"0008134"}}}


id: PBO:0074404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small integral membrane protein 10 like 2B","termid":"PBO:0074404"}


id: PBO:0089461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"translation elongation and termination factor eIF5A (predicted)","termid":"PBO:0089461"}


id: GO:0019403
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactitol metabolic process","termid":"GO:0019402"},{"relation_name":"is_a","term_name":"hexitol biosynthetic process","termid":"GO:0019406"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0005975"],"is_obsolete":false,"name":"galactitol biosynthetic process","synonyms":[{"name":"galactitol anabolism","type":"exact"},{"name":"galactitol biosynthesis","type":"exact"},{"name":"galactitol formation","type":"exact"},{"name":"galactitol synthesis","type":"exact"}],"termid":"GO:0019403"}


id: GO:0047573
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.","definition_xrefs":["EC:3.5.1.63"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"},{"relation_name":"is_a","term_name":"deacetylase activity","termid":"GO:0019213"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0019213"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003824","GO:0016810","GO:0019213","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"4-acetamidobutyrate deacetylase activity","secondary_identifiers":["RHEA:15897","MetaCyc:RXN-36"],"synonyms":[{"name":"4-acetamidobutanoate amidohydrolase activity","type":"related"}],"termid":"GO:0047573"}


id: GO:0050170
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3.","definition_xrefs":["EC:3.5.1.43","MetaCyc:PEPTIDYL-GLUTAMINASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0016810","GO:0003674"],"is_obsolete":false,"name":"peptidyl-glutaminase activity","secondary_identifiers":["RHEA:10032"],"synonyms":[{"name":"peptideglutaminase activity","type":"related"},{"name":"peptidoglutaminase I activity","type":"narrow"},{"name":"peptidoglutaminase activity","type":"related"},{"name":"peptidyl-L-glutamine amidohydrolase activity","type":"related"}],"termid":"GO:0050170"}


id: PBO:0074671
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 57","termid":"PBO:0074671"}


id: GO:0021846
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.","definition_xrefs":["GOC:cls","GOC:dgh","GOC:dph","GOC:jid","GO_REF:0000021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neural precursor cell proliferation","termid":"GO:0061351"},{"relation_name":"part_of","term_name":"forebrain development","termid":"GO:0030900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell proliferation in forebrain","termid":"GO:0021846"}


id: GO:0004977
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with melanocortin to initiate a change in cell activity.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled peptide receptor activity","termid":"GO:0008528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"melanocortin receptor activity","termid":"GO:0004977"}


id: FYPO:0007989
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur because the nuclei fail to come in physical contact.","definition_xrefs":["PMID:25869666","PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nuclear congression during mating","termid":"FYPO:0003062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000301"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0000301"],"is_obsolete":false,"name":"abolished nuclear congression during mating","termid":"FYPO:0007989"}


id: PBO:0066522
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RGMB antisense RNA 1","termid":"PBO:0066522"}


id: SO:0001664
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A discontinuous core element of RNA polymerase II transcribed genes, situated downstream of the TSS. It is composed of three sub elements: SI, SII and SIII.","definition_xrefs":["PMID:16858867"],"direct_ancestors":[{"relation_name":"is_a","term_name":"core_eukaryotic_promoter_element","termid":"SO:0001660"},{"relation_name":"part_of","term_name":"RNApol_II_core_promoter","termid":"SO:0001669"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DCE","synonyms":[{"name":"downstream core element","type":"related"}],"termid":"SO:0001664"}


id: PBO:0038561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ABI family member 3","termid":"PBO:0038561"}


id: FYPO:0005456
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a lower than normal number of cells contain 1C DNA content.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0001985"],"is_obsolete":false,"name":"decreased number of cells with 1C DNA content","synonyms":[{"name":"decreased amount of cells with 1C DNA content","type":"exact"},{"name":"decreased number of cells containing 1C DNA","type":"exact"},{"name":"reduced number of cells with 1C DNA content","type":"exact"}],"termid":"FYPO:0005456"}


id: PR:Q10351
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- gpi17 gene.","definition_xrefs":["UniProtKB:Q10351","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GPI transamidase component PIG-S homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1F12.09","synonyms":[{"name":"Spom972h-gpi17","type":"exact"}],"termid":"PR:Q10351"}


id: PR:Q9Y7M6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- nop52 gene.","definition_xrefs":["UniProtKB:Q9Y7M6","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal RNA-processing protein 1 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC9B6.07","synonyms":[{"name":"Spom972h-nop52","type":"exact"}],"termid":"PR:Q9Y7M6"}


id: PBO:0034574
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-long_stable_microtubule_bundle","termid":"PBO:0034574"}


id: GO:0008289
data:
  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id: MONDO:0013853
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id: PBO:0058581
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id: PATO:0002539
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id: FYPO:0002663
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id: PATO:0015005
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id: GO:1902408
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id: PBO:0083173
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id: GO:0006596
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id: MONDO:0008245
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Piebald trait-neurologic defects syndrome is a rare, genetic, pigmentation anomaly of the skin syndrome characterized by ventral as well as dorsal leukoderma of the trunk and a congenital white forelock, in association with cerebellar ataxia, impaired motor coordination, intellectual disability of variable severity and progressive, mild to profound, uni- or bilateral sensorineural hearing loss. There have been no further descriptions in the literature since 1971.","definition_xrefs":["Orphanet:2885"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypopigmentation of the skin","termid":"MONDO:0019290"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"piebald trait-neurologic defects syndrome","secondary_identifiers":["MESH:C536955","OMIM:172850","UMLS:C1868311","GARD:5133","MEDGEN:358177"],"synonyms":[{"name":"White forelock and leukoderma with neurological impairment","type":"related"},{"name":"piebald trait neurologic defects","type":"related"},{"name":"piebald trait with neurologic defects","type":"related"},{"name":"telfer Sugar Jaeger syndrome","type":"related"},{"name":"telfer-Sugar-Jaeger syndrome","type":"exact"}],"termid":"MONDO:0008245","xrefs":{"Monarch":{"xref_id":"0008245"}}}


id: GO:0018004
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formylation of the N-terminal amino acid of proteins.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein formylation","termid":"GO:0018256"},{"relation_name":"is_a","term_name":"N-terminal protein amino acid modification","termid":"GO:0031365"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"N-terminal protein formylation","termid":"GO:0018004"}


id: PBO:0047571
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibroblast growth factor 22","termid":"PBO:0047571"}


id: MONDO:0003132
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  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rapidly progressive glomerulonephritis (obsolete MONDO:0003132)","termid":"MONDO:0003132","xrefs":{"Monarch":{"xref_id":"0003132"}}}


id: MONDO:1012925
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Focal epilepsy that occurs in crab-eating macaque due to a mutation in the STXBP1 gene created by genetic engineering or gene editing.","definition_xrefs":["PMID:35283272"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neurological disease, non-human animal","termid":"MONDO:1012972"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"encephalopathy, STXBP1-related, crab-eating macaque","secondary_identifiers":["OMIA:002537-9541"],"synonyms":[{"name":"STXBP1 encephalopathy, crab-eating macaque","type":"related"}],"termid":"MONDO:1012925","xrefs":{"Monarch":{"xref_id":"1012925"}}}


id: PBO:0016068
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER protein translocation subcomplex subunit (predicted)","termid":"PBO:0016068"}


id: PBO:0047243
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id: PBO:0082653
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id: GO:0005852
data:
  {"annotated_genes":["SJAG_04744","SJAG_02628","SJAG_03472","SJAG_02995","SJAG_04900","SJAG_03147","SJAG_02376","SJAG_02164","SJAG_04891","SJAG_04981","SJAG_00662"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[72609],"is_not":false,"summary":null,"term":"GO:0005852"},{"annotations":[95122,68779,75455,111007,98057,98116,105928,99253],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071540"},{"annotations":[97183,75456,95123,74711,98058,59617,99254,105929,76020],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071541"}]},"cv_name":"cellular_component","definition":"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.","definition_xrefs":["PMID:15904532"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00662":null,"SJAG_02164":null,"SJAG_02376":null,"SJAG_02628":null,"SJAG_02995":null,"SJAG_03147":null,"SJAG_03472":null,"SJAG_04744":null,"SJAG_04891":null,"SJAG_04900":null,"SJAG_04981":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005737","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"eukaryotic translation initiation factor 3 complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"synonyms":[{"name":"eIF-3","type":"exact"},{"name":"eIF3","type":"exact"}],"termid":"GO:0005852","terms_by_termid":{"GO:0005852":null,"GO:0071540":null,"GO:0071541":null}}


id: GO:0060111
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively.","definition_xrefs":["GOC:dph","ISSN:15518507","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cuticular extracellular matrix","termid":"GO:0060102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"alae of collagen and cuticulin-based cuticle extracellular matrix","synonyms":[{"name":"alae of collagen and cuticulin-based exoskeleton extracellular matrix","type":"related"}],"termid":"GO:0060111"}


id: MONDO:0006455
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare primary thymic carcinoma, characterized by an undifferentiated solid tumor growth, without associated sarcomatoid features.","definition_xrefs":["NCIT:C35718"],"direct_ancestors":[{"relation_name":"is_a","term_name":"undifferentiated carcinoma","termid":"MONDO:0005617"},{"relation_name":"is_a","term_name":"thymic carcinoma","termid":"MONDO:0006451"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046","MONDO:0004992"],"is_obsolete":false,"name":"thymic undifferentiated carcinoma","secondary_identifiers":["MEDGEN:234452","EFO:1000580","UMLS:C1336865"],"synonyms":[{"name":"thymic undifferentiated carcinoma","type":"exact"}],"termid":"MONDO:0006455","xrefs":{"Monarch":{"xref_id":"0006455"}}}


id: GO:0046896
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine.","definition_xrefs":["RESID:AA0337"],"gene_count":0,"genotype_count":0,"name":"obsolete N-terminal peptidyl-leucine methylation (obsolete GO:0046896)","termid":"GO:0046896"}


id: MONDO:0009957
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Reese retinal dysplasia","secondary_identifiers":["MESH:C564854","OMIM:266400","MEDGEN:341456","UMLS:C1849450"],"synonyms":[{"name":"Reese retinal dysplasia","type":"exact"}],"termid":"MONDO:0009957","xrefs":{"Monarch":{"xref_id":"0009957"}}}


id: GO:1903581
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of basophil degranulation.","definition_xrefs":["PMID:10880837","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of myeloid leukocyte mediated immunity","termid":"GO:0002886"},{"relation_name":"is_a","term_name":"regulation of leukocyte degranulation","termid":"GO:0043300"},{"relation_name":"is_a","term_name":"regulation of immune response","termid":"GO:0050776"},{"relation_name":"regulates","term_name":"basophil degranulation","termid":"GO:0002561"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0016192"],"is_obsolete":false,"name":"regulation of basophil degranulation","termid":"GO:1903581"}


id: PBO:0091805
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane ClC chloride channel","termid":"PBO:0091805"}


id: GO:1904432
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of ferrous iron binding.","definition_xrefs":["GOC:kom","GOC:TermGenie","PMID:18353247","GO_REF:0000059","GOC:BHF"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of ferrous iron binding (obsolete GO:1904432)","termid":"GO:1904432"}


id: MONDO:0013699
data:
  {"annotated_genes":["SJAG_02187"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85996],"is_not":false,"summary":null,"term":"MONDO:0013699"}]},"cv_name":"mondo","definition":"Any hereditary nonpolyposis colon cancer in which the cause of the disease is a mutation in the PMS2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"Lynch syndrome","termid":"MONDO:0005835"},{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"hereditary nonpolyposis colon cancer","termid":"MONDO:0018630"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02187":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335","MONDO:0000426"],"is_obsolete":false,"name":"Lynch syndrome 4","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:325005","OMIM:614337","UMLS:C1838333","DOID:0070275","GARD:15791","MESH:C563971"],"synonyms":[{"name":"HNPCC4","type":"related"},{"name":"PMS2 hereditary nonpolyposis colon cancer","type":"exact"},{"name":"colorectal cancer, hereditary nonpolyposis, type 4","type":"exact"},{"name":"hereditary nonpolyposis colon cancer caused by mutation in PMS2","type":"exact"}],"termid":"MONDO:0013699","terms_by_termid":{"MONDO:0013699":null},"xrefs":{"Monarch":{"xref_id":"0013699"}}}


id: PBO:0031016
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_cisplatin","termid":"PBO:0031016"}


id: MONDO:1012302
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spondylosis deformans, non-human animal","termid":"MONDO:1011955"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spondylosis deformans, domestic cat","secondary_identifiers":["OMIA:001132-9685"],"termid":"MONDO:1012302","xrefs":{"Monarch":{"xref_id":"1012302"}}}


id: PBO:0087237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sequence-specific DNA binding protein; binds to a sequence motif associated with distinct genomic hotspots of non-H2B protein ubiquitylation (ub-hotspots); interacts with Slx5p to recruit the Slx5-Slx8  SUMO-targeted Ub ligase (STUbL) complex to ub-hotspots; deletion prevents ub-hotspot formation and exacerbates heat sensitivity of cells deficient in Rpd3L histone deacetylase complex members; forms nuclear foci upon DNA replication stress","termid":"PBO:0087237"}


id: PBO:0088488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein N-terminal amidase Nta1","termid":"PBO:0088488"}


id: MONDO:0016483
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An intracranial aneurysm with a characteristic rounded shape; the most common form of cerebral aneurysm.","definition_xrefs":["DOID:0060228"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brain aneurysm","termid":"MONDO:0005291"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intracranial berry aneurysm","secondary_identifiers":["MEDGEN:825711","icd11.foundation:59881644","Orphanet:231160","SCTID:703226008","GARD:17161","UMLS:C3839866","OMIMPS:105800","HP:0007029"],"synonyms":[{"name":"aneurysm, intracranial berry","type":"exact"},{"name":"familial aneurysmal subarachnoid haemorrhage","type":"exact"},{"name":"familial aneurysmal subarachnoid hemorrhage","type":"exact"},{"name":"familial berry aneurysm","type":"exact"},{"name":"familial cerebral saccular aneurysm","type":"related"},{"name":"familial intracranial saccular aneurysm","type":"exact"},{"name":"saccular cerebral aneurysm","type":"exact"}],"termid":"MONDO:0016483","xrefs":{"Monarch":{"xref_id":"0016483"}}}


id: MONDO:0015837
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Unicervical bicornuate uterus (obsolete MONDO:0015837)","secondary_identifiers":["Orphanet:180114"],"termid":"MONDO:0015837","xrefs":{"Monarch":{"xref_id":"0015837"}}}


id: FYPO:0003488
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated during a cellular response to ionizing radiation.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete elongated cell during cellular response to ionizing radiation (obsolete FYPO:0003488)","synonyms":[{"name":"elongated cell during cellular response to IR","type":"exact"},{"name":"elongated cell during cellular response to ionizing radiation during mitotic cell cycle","type":"related"},{"name":"elongated cell during cellular response to ionizing radiation during vegetative growth","type":"exact"},{"name":"elongated in response to ionizing radiation","type":"exact"}],"termid":"FYPO:0003488"}


id: PBO:0069273
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 529, pseudogene","termid":"PBO:0069273"}


id: MONDO:0002769
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Whitish or yellowish mucosal vaginal discharge.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vaginal discharge","termid":"MONDO:0002770"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukorrhea","secondary_identifiers":["UMLS:C0023533","DOID:3766","MESH:D007973","MEDGEN:44134"],"synonyms":[{"name":"discharge - leukorrhea","type":"exact"},{"name":"leukorrhea of vagina","type":"exact"}],"termid":"MONDO:0002769","xrefs":{"Monarch":{"xref_id":"0002769"}}}


id: GO:0045152
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"antisigma factor binding","synonyms":[{"name":"antisigma factor antagonist activity","type":"narrow"}],"termid":"GO:0045152"}


id: PBO:0012281
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae SEC12","termid":"PBO:0012281"}


id: MONDO:1010618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Microcephaly that occurs in sheep.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microcephaly, non-human animal","termid":"MONDO:1010066"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microcephaly, sheep","secondary_identifiers":["OMIA:000645-9940"],"termid":"MONDO:1010618","xrefs":{"Monarch":{"xref_id":"1010618"}}}


id: PBO:0068806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 43, pseudogene","termid":"PBO:0068806"}


id: GO:0106064
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.","definition_xrefs":["PMID:29056341"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of vitamin metabolic process","termid":"GO:0030656"},{"relation_name":"is_a","term_name":"regulation of tetrapyrrole metabolic process","termid":"GO:1901401"},{"relation_name":"regulates","term_name":"cobalamin metabolic process","termid":"GO:0009235"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006766"},{"rel_name":"regulates","termid":"GO:0033013"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006766","GO:0033013"],"is_obsolete":false,"name":"regulation of cobalamin metabolic process","termid":"GO:0106064"}


id: PBO:0059679
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 45","termid":"PBO:0059679"}


id: PBO:0082961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly","termid":"PBO:0082961"}


id: GO:0034031
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.","definition_xrefs":["GOC:mah","GOC:pde"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside bisphosphate catabolic process","termid":"GO:0033869"},{"relation_name":"is_a","term_name":"ribonucleoside bisphosphate metabolic process","termid":"GO:0033875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086"],"is_obsolete":false,"name":"ribonucleoside bisphosphate catabolic process","synonyms":[{"name":"ribonucleoside bisphosphate breakdown","type":"exact"},{"name":"ribonucleoside bisphosphate catabolism","type":"exact"},{"name":"ribonucleoside bisphosphate degradation","type":"exact"}],"termid":"GO:0034031"}


id: GO:1902678
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage).","definition_xrefs":["PMID:5961344","GO_REF:0000064","GOC:TermGenie","ISBN:9780124260207","PMID:16607022","GOC:giardia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ciliary basal body","termid":"GO:0036064"},{"relation_name":"part_of","term_name":"right caudal flagellum","termid":"GO:0097561"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0005575","GO:0015630"],"is_obsolete":false,"name":"right caudal basal body","synonyms":[{"name":"cilial basal body of right caudal cilium","type":"exact"},{"name":"cilial basal body of right caudal flagellum","type":"exact"},{"name":"ciliary basal body of right caudal cilium","type":"exact"},{"name":"ciliary basal body of right caudal flagellum","type":"exact"},{"name":"cilium basal body of right caudal cilium","type":"exact"},{"name":"cilium basal body of right caudal flagellum","type":"exact"},{"name":"microtubule basal body of right caudal cilium","type":"exact"},{"name":"microtubule basal body of right caudal flagellum","type":"exact"},{"name":"right caudal flagellum ciliary basal body","type":"exact"}],"termid":"GO:1902678"}


id: MONDO:0018162
data:
  {"annotated_genes":["SJAG_02791","SJAG_04449","SJAG_02313"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85835],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009736"},{"annotations":[87231],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014466"},{"annotations":[87273],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011152"},{"annotations":[86876],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012596"},{"annotations":[86296],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013531"}]},"cv_name":"mondo","definition":"Serine-deficiency syndrome is a very rare infantile-onset potentially treatable neurometabolic disorder characterized clinically by microcephaly, neurodevelopmental disorders and seizures. Three serine-deficiency syndromes have been described: 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, 3-phosphoserine phosphatase (3-PSP) deficiency, and phosphoserine aminotransferase deficiency.","definition_xrefs":["Orphanet:35705"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn serine deficiency","termid":"MONDO:0000421"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02313":null,"SJAG_02791":null,"SJAG_04449":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"neurometabolic disorder due to serine deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5680148","GARD:18815","MEDGEN:1842451"],"synonyms":[{"name":"neurometabolic disorder due to serine deficiency","type":"exact"},{"name":"serine deficiency","type":"exact"}],"termid":"MONDO:0018162","terms_by_termid":{"MONDO:0009736":null,"MONDO:0011152":null,"MONDO:0012596":null,"MONDO:0013531":null,"MONDO:0014466":null},"xrefs":{"Monarch":{"xref_id":"0018162"}}}


id: PBO:0062499
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 8 subfamily D member 4","termid":"PBO:0062499"}


id: GO:0090137
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration.","definition_xrefs":["GOC:tb","GOC:ascb_2009","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell-cell adhesion","termid":"GO:0090136"},{"relation_name":"part_of","term_name":"epithelium migration","termid":"GO:0090132"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"epithelial cell-cell adhesion involved in epithelium migration","termid":"GO:0090137"}


id: GO:0070409
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.","definition_xrefs":["GOC:rph","GOC:mah","CHEBI:17672"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbamoyl phosphate metabolic process","termid":"GO:0070408"},{"relation_name":"is_a","term_name":"organophosphate biosynthetic process","termid":"GO:0090407"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"carbamoyl phosphate biosynthetic process","synonyms":[{"name":"carbamoyl phosphate anabolism","type":"exact"},{"name":"carbamoyl phosphate biosynthesis","type":"exact"},{"name":"carbamoyl phosphate formation","type":"exact"},{"name":"carbamoyl phosphate synthesis","type":"exact"},{"name":"carbamyl phosphate biosynthetic process","type":"exact"}],"termid":"GO:0070409"}


id: PBO:0068218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 525","termid":"PBO:0068218"}


id: MONDO:0017436
data:
  {"annotated_genes":["SJAG_03847","SJAG_01863"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86536],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009670"},{"annotations":[85839],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012656"}]},"cv_name":"mondo","definition":"A syndrome characterized by congenital nonprogressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth.","definition_xrefs":["DOID:0060558","PMID:22610851"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"arthrogryposis syndrome","termid":"MONDO:0015225"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01863":null,"SJAG_03847":null},"genotype_count":0,"is_obsolete":false,"name":"lethal congenital contracture syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1863860","Orphanet:294965","GARD:12643","OMIMPS:253310","icd11.foundation:1866017256","UMLS:C5848326"],"synonyms":[{"name":"LCCS","type":"exact"}],"termid":"MONDO:0017436","terms_by_termid":{"MONDO:0009670":null,"MONDO:0012656":null},"xrefs":{"Monarch":{"xref_id":"0017436"}}}


id: PR:Q10168
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A nuclear pore glycoprotein p62 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR12084:SF0","PRO:DNx","OMA:SCHPO01401"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleoporin nsp1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC26A3.15c","secondary_identifiers":["UniProtKB:Q10168"],"synonyms":[{"name":"Spom972h-NUP62","type":"exact"},{"name":"nuclear pore protein nsp1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"nucleoskeletal-like protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10168"}


id: PATO:0000609
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A morphological quality inhering in a bearer by virtue of the bearer's affording not completed blocked passage or view.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"open","termid":"PATO:0000610"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"closure incomplete","termid":"PATO:0000609"}


id: PBO:0061140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NME/NM23 nucleoside diphosphate kinase 3","termid":"PBO:0061140"}


id: PBO:0055142
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2561","termid":"PBO:0055142"}


id: PBO:0053441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 387","termid":"PBO:0053441"}


id: PBO:0017747
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IMPACT homolog, cytoplasmic translational regulator Yih1 (predicted)","termid":"PBO:0017747"}


id: PBO:0035769
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_magnesium_level","termid":"PBO:0035769"}


id: MONDO:0006180
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation.","definition_xrefs":["NCIT:C36207"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"digestive system cancer","termid":"MONDO:0002516"},{"relation_name":"is_a","term_name":"adenoma","termid":"MONDO:0004972"},{"relation_name":"is_a","term_name":"digestive system neoplasm","termid":"MONDO:0021223"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"digestive system adenoma","secondary_identifiers":["DOID:4147","MEDGEN:184920","EFO:1000217","UMLS:C0948101"],"synonyms":[{"name":"GI adenoma","type":"exact"},{"name":"digestive system adenoma","type":"exact"},{"name":"digestive tract adenoma","type":"exact"},{"name":"gastrointestinal adenoma","type":"exact"}],"termid":"MONDO:0006180","xrefs":{"Monarch":{"xref_id":"0006180"}}}


id: MONDO:0019521
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Centripetalis recessive dystrophic epidermolysis bullosa (RDEB-Ce) is an extremely rare subtype of dystrophic epidermolysis bullosa (DEB), characterized by blistering which begins acrally and then progressively spreads toward the trunk.","definition_xrefs":["Orphanet:89841"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epidermolysis bullosa dystrophica","termid":"MONDO:0006543"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"centripetalis recessive dystrophic epidermolysis bullosa","secondary_identifiers":["MEDGEN:1377762","SCTID:725419003","UMLS:C4511056"],"synonyms":[{"name":"RDEB, centripetalis","type":"exact"},{"name":"RDEB-Ce","type":"exact"},{"name":"centripetal dystrophic epidermolysis bullosa","type":"exact"},{"name":"centripetal recessive dystrophic epidermolysis bullosa","type":"exact"}],"termid":"MONDO:0019521","xrefs":{"Monarch":{"xref_id":"0019521"}}}


id: PBO:0065651
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase receptor type D","termid":"PBO:0065651"}


id: PBO:0057963
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3684","termid":"PBO:0057963"}


id: PBO:0002982
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aminotransferase class-III, unknown specificity","termid":"PBO:0002982"}


id: PBO:0084809
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching","termid":"PBO:0084809"}


id: FYPO:0006630
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetative cell is inviable, elongated, has no septum, and contains four nuclei.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable elongated multinucleate aseptate vegetative cell","termid":"FYPO:0002024"},{"relation_name":"is_a","term_name":"elongated tetranucleate vegetative cell","termid":"FYPO:0004044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000004"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000004","FYPO:0000005","FYPO:0000002","FYPO:0001320","FYPO:0000631","FYPO:0000032","FYPO:0005447"],"is_obsolete":false,"name":"inviable elongated tetranucleate aseptate vegetative cell","synonyms":[{"name":"elongated tetranucleate aseptate inviable vegetative cell","type":"exact"},{"name":"inviable elongated tetranucleate aseptate cell during vegetative growth","type":"exact"},{"name":"inviable elongated tetranucleate aseptate vegetative cell during mitotic cell cycle","type":"related"},{"name":"lethal; elongated tetranucleate aseptate vegetative cell","type":"exact"}],"termid":"FYPO:0006630"}


id: MONDO:0013844
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"stutter disorder","termid":"MONDO:0000723"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stuttering, familial persistent, 4","secondary_identifiers":["OMIM:614668","MEDGEN:766317","UMLS:C3553403"],"synonyms":[{"name":"STUT4","type":"exact"},{"name":"stuttering, familial persistent, 4","type":"exact"}],"termid":"MONDO:0013844","xrefs":{"Monarch":{"xref_id":"0013844"}}}


id: MONDO:0019820
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital heart malformation","termid":"MONDO:0019512"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"univentricular cardiopathy","secondary_identifiers":["GARD:19269","UMLS:C5681576","Orphanet:95483","MEDGEN:1843389"],"termid":"MONDO:0019820","xrefs":{"Monarch":{"xref_id":"0019820"}}}


id: PBO:0048311
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyceraldehyde 3 phosphate dehydrogenase pseudogene 22","termid":"PBO:0048311"}


id: PBO:0054484
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1884","termid":"PBO:0054484"}


id: GO:0015495
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).","definition_xrefs":["TC:2.A.18.5.1","TC:2.A.3.1.4","TC:2.A.3.4.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid:proton symporter activity","termid":"GO:0005280"},{"relation_name":"is_a","term_name":"gamma-aminobutyric acid transmembrane transporter activity","termid":"GO:0015185"},{"relation_name":"is_a","term_name":"secondary active monocarboxylate transmembrane transporter activity","termid":"GO:0015355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"gamma-aminobutyric acid:proton symporter activity","secondary_identifiers":["GO:0015329","RHEA:28915","GO:0005331","MetaCyc:TRANS-RXN-57","Reactome:R-HSA-428625"],"synonyms":[{"name":"4-aminobutanoate:hydrogen symporter activity","type":"exact"},{"name":"4-aminobutanoate:proton symporter activity","type":"exact"},{"name":"4-aminobutyrate:hydrogen symporter activity","type":"exact"},{"name":"4-aminobutyrate:proton symporter activity","type":"exact"},{"name":"GABA:hydrogen symporter activity","type":"exact"},{"name":"GABA:proton symporter activity","type":"exact"},{"name":"gamma-aminobutyric acid permease activity","type":"exact"},{"name":"gamma-aminobutyric acid:hydrogen symporter activity","type":"exact"}],"termid":"GO:0015495"}


id: MONDO:0025691
data:
  {"annotated_genes":["SJAG_01598"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86937],"is_not":false,"summary":null,"term":"MONDO:0025691"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited dystonia","termid":"MONDO:0044807"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01598":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"dystonia 30","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1785079","DOID:0060937","UMLS:C5543312","OMIM:619291"],"synonyms":[{"name":"DYT30","type":"exact"}],"termid":"MONDO:0025691","terms_by_termid":{"MONDO:0025691":null},"xrefs":{"Monarch":{"xref_id":"0025691"}}}


id: PBO:0069749
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1031, pseudogene","termid":"PBO:0069749"}


id: MONDO:0000829
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete early-onset Parkinson disease (obsolete MONDO:0000829)","termid":"MONDO:0000829","xrefs":{"Monarch":{"xref_id":"0000829"}}}


id: PBO:0057740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1470","termid":"PBO:0057740"}


id: PBO:0027027
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_level_of_iron_homeostasis_gene_mRNA_during_vegetative_growth","termid":"PBO:0027027"}


id: MONDO:0014923
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any peeling skin syndrome in which the cause of the disease is a mutation in the SERPINB8 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"exfoliative ichthyosis","termid":"MONDO:0017339"},{"relation_name":"is_a","term_name":"peeling skin syndrome","termid":"MONDO:0019347"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"peeling skin syndrome 5","secondary_identifiers":["OMIM:617115","DOID:0070524","UMLS:C4310710","GARD:18427","MEDGEN:934677"],"synonyms":[{"name":"PSS5","type":"exact"},{"name":"SERPINB8 peeling skin syndrome","type":"exact"},{"name":"peeling skin syndrome 5","type":"exact"},{"name":"peeling skin syndrome 5; PSS5","type":"exact"},{"name":"peeling skin syndrome caused by mutation in SERPINB8","type":"exact"},{"name":"peeling skin syndrome type 5","type":"exact"}],"termid":"MONDO:0014923","xrefs":{"Monarch":{"xref_id":"0014923"}}}


id: FYPO:0007374
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of histones in centromeric regions is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone methylation during vegetative growth","termid":"FYPO:0000457"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0002494","FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"abnormal histone methylation at centromere during vegetative growth","synonyms":[{"name":"abnormal centromeric histone methylation during vegetative growth","type":"exact"},{"name":"abnormal histone methylation at centromere during mitotic cell cycle","type":"related"}],"termid":"FYPO:0007374"}


id: MONDO:0008396
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Oculodental syndrome, Rutherfurd type is a rare genetic disorder that is primarily characterized by the classical triad of gingival fibromatosis, non-eruption of tooth and corneal dystrophy (bilateral corneal vascularization and opacity). Abnormally shaped teeth have also been reported. The syndrome is transmitted as an autosomal dominant trait.","definition_xrefs":["Orphanet:2709"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oculodental syndrome, Rutherfurd type","secondary_identifiers":["OMIM:180900","MESH:C537732","SCTID:699754008","UMLS:C0796140","GARD:212","MEDGEN:163222","icd11.foundation:183543626","ICD9:759.89"],"synonyms":[{"name":"Rutherfurd syndrome","type":"exact"},{"name":"corneal dystrophy with gum Hypertrophy","type":"exact"},{"name":"corneal dystrophy with gum hypertrophy","type":"exact"},{"name":"gingival Hypertrophy with corneal dystrophy","type":"exact"},{"name":"gingival hypertrophy corneal dystrophy","type":"exact"},{"name":"gingival hypertrophy-corneal dystrophy","type":"exact"}],"termid":"MONDO:0008396","xrefs":{"Monarch":{"xref_id":"0008396"}}}


id: PBO:0058347
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4720","termid":"PBO:0058347"}


id: MONDO:0032612
data:
  {"annotated_genes":["SJAG_00217"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86596],"is_not":false,"summary":null,"term":"MONDO:0032612"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial complex I deficiency, nuclear type","termid":"MONDO:0100223"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00217":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial complex 1 deficiency, nuclear type 7","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:618229","UMLS:C4748760","MEDGEN:1648484","DOID:0112092","GARD:16317"],"synonyms":[{"name":"MC1DN7","type":"related"},{"name":"MITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 7","type":"related"}],"termid":"MONDO:0032612","terms_by_termid":{"MONDO:0032612":null},"xrefs":{"Monarch":{"xref_id":"0032612"}}}


id: GO:0140811
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + histone 2A L-arginyl (position 3)= histone 2A L-citrullyl (position 3) + NH4+, resulting in histone H2A citrullination at position 3.","definition_xrefs":["PMID:15823041"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone arginine deiminase activity","termid":"GO:0140794"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0016810","GO:0140096","GO:0003824","GO:0016787","GO:0003674"],"is_obsolete":false,"name":"histone H2AR3 arginine deiminase activity","synonyms":[{"name":"H2A-R3 citrullination","type":"exact"},{"name":"histone H2A-R3 arginine deiminase activity","type":"exact"},{"name":"histone-arginine deiminase activity (H2A-R3 specific)","type":"exact"}],"termid":"GO:0140811"}


id: FYECO:0000277
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which bleomycin was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ bleomycin","termid":"FYECO:0000277"}


id: MONDO:0018268
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Medich giant platelet syndrome (MGPS) is a platelet granule disorder characterized by thrombocytopenia with giant platelets resulting in easy bleeding.","definition_xrefs":["Orphanet:370127"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha granule disease","termid":"MONDO:0020117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"Medich giant platelet syndrome","secondary_identifiers":["SCTID:718554005","UMLS:C4305375","MEDGEN:931044","GARD:21598"],"synonyms":[{"name":"Medich macrothrombocytopenia","type":"exact"}],"termid":"MONDO:0018268","xrefs":{"Monarch":{"xref_id":"0018268"}}}


id: PBO:0005745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ammonium transporter Amt1","termid":"PBO:0005745"}


id: GO:0030984
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a kininogen, a kinin precursor.","definition_xrefs":["PMID:9520414","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"kininogen binding","termid":"GO:0030984"}


id: GO:1902811
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:17879321","GOC:mr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of myotube differentiation","termid":"GO:0010831"},{"relation_name":"is_a","term_name":"regulation of skeletal muscle fiber differentiation","termid":"GO:1902809"},{"relation_name":"is_a","term_name":"positive regulation of skeletal muscle cell differentiation","termid":"GO:2001016"},{"relation_name":"positively_regulates","term_name":"skeletal muscle fiber differentiation","termid":"GO:0098528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of skeletal muscle fiber differentiation","synonyms":[{"name":"activation of skeletal muscle fiber differentiation","type":"narrow"},{"name":"up regulation of skeletal muscle fiber differentiation","type":"exact"},{"name":"up-regulation of skeletal muscle fiber differentiation","type":"exact"},{"name":"upregulation of skeletal muscle fiber differentiation","type":"exact"}],"termid":"GO:1902811"}


id: GO:0051955
data:
  {"annotated_genes":["SJAG_05346","SJAG_00991","SJAG_02605","SJAG_03591","SJAG_03970"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88432],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905533"},{"annotations":[99204,110851,92080,93674],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905589"},{"annotations":[93675,99205,92081],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905534"},{"annotations":[93676],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905626"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amine transport","termid":"GO:0051952"},{"relation_name":"regulates","term_name":"amino acid transport","termid":"GO:0006865"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00991":null,"SJAG_02605":null,"SJAG_03591":null,"SJAG_03970":null,"SJAG_05346":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of amino acid transport","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0051955","terms_by_termid":{"GO:1905533":null,"GO:1905534":null,"GO:1905589":null,"GO:1905626":null}}


id: PBO:0057961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3682","termid":"PBO:0057961"}


id: GO:0072142
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell development","termid":"GO:0048468"},{"relation_name":"part_of","term_name":"juxtaglomerulus cell differentiation","termid":"GO:0072052"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"juxtaglomerulus cell development","termid":"GO:0072142"}


id: MONDO:0011199
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"primary sclerosing cholangitis","termid":"MONDO:0013433"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"nephropathy, progressive tubulointerstitial, with cholestatic liver disease","secondary_identifiers":["OMIM:602114","UMLS:C1865831","GARD:15344","MEDGEN:355562","MESH:C566573"],"synonyms":[{"name":"nephropathy, progressive tubulointerstitial, with cholestatic liver disease","type":"exact"}],"termid":"MONDO:0011199","xrefs":{"Monarch":{"xref_id":"0011199"}}}


id: GO:0052241
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete positive chemotaxis on or near other organism involved in symbiotic interaction (obsolete GO:0052241)","synonyms":[{"name":"positive chemotaxis on or near other organism during symbiotic interaction","type":"related"}],"termid":"GO:0052241"}


id: GO:0019271
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.","definition_xrefs":["PMID:23192658","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tricarboxylic acid transport","termid":"GO:0006842"},{"relation_name":"is_a","term_name":"modified amino acid transport","termid":"GO:0072337"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"aerobactin transport","termid":"GO:0019271"}


id: GO:0034912
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+.","definition_xrefs":["UM-BBD_reactionID:r1445"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"phthalate 3,4-cis-dihydrodiol dehydrogenase activity","secondary_identifiers":["MetaCyc:RXN5F9-56"],"termid":"GO:0034912"}


id: PBO:0068712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4atac small nuclear","termid":"PBO:0068712"}


id: FYECO:0000250
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which silver nitrate was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ AgNO3","synonyms":[{"name":"+ silver nitrate","type":"exact"}],"termid":"FYECO:0000250"}


id: PBO:0091344
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"previously annotated as caf4, with both caf4 and mdv1 as S. cerevisiae orthologs","termid":"PBO:0091344"}


id: PBO:0074772
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 3E","termid":"PBO:0074772"}


id: PBO:0054480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1880","termid":"PBO:0054480"}


id: PBO:0085759
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication","termid":"PBO:0085759"}


id: PR:Q9UT70
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A trafficking protein particle complex subunit 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01316","PRO:DNx","PANTHER:PTHR23249:SF9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transport protein particle subunit bet5 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3G9.16c","secondary_identifiers":["UniProtKB:Q9UT70"],"synonyms":[{"name":"Spom972h-TRAPPC1","type":"exact"}],"termid":"PR:Q9UT70"}


id: GO:0010088
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formation of the principal food-conducting tissue of a vascular plant.","definition_xrefs":["GOC:tb","ISBN:0471245208"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phloem or xylem histogenesis","termid":"GO:0010087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"phloem development","synonyms":[{"name":"phloem histogenesis","type":"exact"}],"termid":"GO:0010088"}


id: GO:0002829
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of type 2 immune response","termid":"GO:0002828"},{"relation_name":"is_a","term_name":"negative regulation of immune response","termid":"GO:0050777"},{"relation_name":"negatively_regulates","term_name":"type 2 immune response","termid":"GO:0042092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of type 2 immune response","synonyms":[{"name":"down regulation of type 2 immune response","type":"exact"},{"name":"down-regulation of type 2 immune response","type":"exact"},{"name":"downregulation of type 2 immune response","type":"exact"},{"name":"inhibition of type 2 immune response","type":"narrow"},{"name":"negative regulation of T-helper 2 type immune response","type":"narrow"},{"name":"negative regulation of Th2 immune response","type":"narrow"}],"termid":"GO:0002829"}


id: MONDO:0005917
data:
  {"annotated_genes":["SJAG_01156"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87476],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032747"}]},"cv_name":"mondo","definition":"A disease involving the placenta.","direct_ancestors":[{"relation_name":"is_a","term_name":"uterine disorder","termid":"MONDO:0002654"},{"relation_name":"is_a","term_name":"pregnancy disorder","termid":"MONDO:0024575"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01156":null},"genotype_count":0,"is_obsolete":false,"name":"placenta disorder","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:656.70","MESH:D010922","NCIT:C26857","MEDGEN:10781","UMLS:C0032045","DOID:780","EFO:0007441","SCTID:125586008","ICD9:646.9"],"synonyms":[{"name":"disease of placenta","type":"exact"},{"name":"disease or disorder of placenta","type":"exact"},{"name":"disease, placenta","type":"related"},{"name":"disease, placental","type":"related"},{"name":"diseases, placenta","type":"related"},{"name":"diseases, placental","type":"related"},{"name":"disorder of placenta","type":"exact"},{"name":"disorder, placenta","type":"related"},{"name":"disorders, placenta","type":"related"},{"name":"placenta disease","type":"exact"},{"name":"placenta disease or disorder","type":"exact"},{"name":"placenta diseases","type":"exact"},{"name":"placenta disorder","type":"exact"},{"name":"placenta disorders","type":"exact"},{"name":"placental disease","type":"related"},{"name":"placental diseases","type":"related"},{"name":"placental disorder","type":"exact"}],"termid":"MONDO:0005917","terms_by_termid":{"MONDO:0032747":null},"xrefs":{"Monarch":{"xref_id":"0005917"}}}


id: PBO:0088886
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol phosphatase","termid":"PBO:0088886"}


id: GO:0016477
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.","definition_xrefs":["Wikipedia:Cell_migration","GOC:cjm","GOC:dph","GOC:ems","GOC:pf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell motility","termid":"GO:0048870"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell migration","termid":"GO:0016477"}


id: MONDO:0010540
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A genetic disorder characterized by formation of bullae without traumatic origin, alopecia, hyperpigmentation, acrocyanosis, short stature, microcephaly, intellectual deficit, tapering fingers and nail abnormalities. Two families (one of whom was Dutch and the other Italian) have been described up to now, in which only males were affected. Transmission is X-linked recessive. The bullous dystrophy locus has been mapped to Xq26.3 in the Italian family and to Xq27.3 in the Dutch family.","definition_xrefs":["Orphanet:1867"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"skin disorder","termid":"MONDO:0005093"},{"relation_name":"excluded_subClassOf","term_name":"epidermal disease","termid":"MONDO:0019268"},{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bullous dystrophy, macular type","secondary_identifiers":["GARD:1038","MESH:C563065","MEDGEN:167089","OMIM:302000","UMLS:C0795974"],"synonyms":[{"name":"EBM","type":"related"},{"name":"bullous dystrophy hereditary macular type","type":"related"},{"name":"bullous dystrophy, hereditary macular type","type":"related"},{"name":"epidermolysis bullosa macular type","type":"related"},{"name":"epidermolysis bullosa, macular type","type":"related"}],"termid":"MONDO:0010540","xrefs":{"Monarch":{"xref_id":"0010540"}}}


id: GO:0120204
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2.","definition_xrefs":["PMID:31043749"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","termid":"GO:0016705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity","termid":"GO:0120204"}


