# terms

id: GO:0008912
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+.","definition_xrefs":["EC:1.1.1.77"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"lactaldehyde reductase activity","synonyms":[{"name":"(R)- or (S)-propane-1,2-diol:NAD+ oxidoreductase activity","type":"related"},{"name":"lactaldehyde:propanediol oxidoreductase activity","type":"related"},{"name":"propanediol oxidoreductase activity","type":"broad"},{"name":"propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity","type":"related"}],"termid":"GO:0008912"}


id: PBO:0017441
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-regulates_expression_of","termid":"PBO:0017441"}


id: MONDO:0024462
data:
  {"annotated_genes":["SJAG_05979","SJAG_02194","SJAG_00757"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87639],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013510"},{"annotations":[87618],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014056"},{"annotations":[86780],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014368"}]},"cv_name":"mondo","definition":"A susceptibility or predisposition to cutaneous melanoma (disease) that is caused by an inherited modification of the individual's genome.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00757":null,"SJAG_02194":null,"SJAG_05979":null},"genotype_count":0,"is_obsolete":false,"name":"susceptibility to familial cutaneous melanoma","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIMPS:155600","MEDGEN:1388845","UMLS:C4511622"],"synonyms":[{"name":"hereditary cutaneous melanoma (disease)","type":"exact"},{"name":"melanoma, cutaneous malignant","type":"exact"}],"termid":"MONDO:0024462","terms_by_termid":{"MONDO:0013510":null,"MONDO:0014056":null,"MONDO:0014368":null},"xrefs":{"Monarch":{"xref_id":"0024462"}}}


id: GO:0018919
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.","definition_xrefs":["UM-BBD_pathwayID:ghch"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexachlorocyclohexane metabolic process","termid":"GO:0019497"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process","secondary_identifiers":["MetaCyc:GAMMAHEXCHLORDEG-PWY"],"synonyms":[{"name":"gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolism","type":"exact"}],"termid":"GO:0018919"}


id: PBO:0084500
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Meiosis-specific protein required for meiotic recombination; makes DNA double-strand breaks (DSB) during meiotic recombination, homolog pairing, and synaptonemal complex formation; role in meiotic DSB formation involves a topo-II-like transesterase mechanism; forms monotetrameric complex; covalently linked to DSBs through a 5'-phosphodiester bond between a catalytic tyrosine (Y135) and the DSB 5'- end; sequence similarity to a topo VI subunit from archaea, fission yeast rec12 and human SPO11","termid":"PBO:0084500"}


id: GO:0070580
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.","definition_xrefs":["PMID:19114062"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA modification","termid":"GO:0006304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006259"],"is_obsolete":false,"name":"base J metabolic process","synonyms":[{"name":"base J metabolism","type":"exact"},{"name":"beta-D-glucosyl-HOMedU metabolic process","type":"exact"},{"name":"beta-D-glucosyl-hydroxymethyluracil metabolism","type":"exact"}],"termid":"GO:0070580"}


id: MONDO:0015043
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"plasmacytoma","termid":"MONDO:0005615"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"extramedullary soft tissue plasmacytoma","secondary_identifiers":["ICD10CM:C90.2","MEDGEN:1842608","UMLS:C2211567","GARD:19740","Orphanet:100022"],"termid":"MONDO:0015043","xrefs":{"Monarch":{"xref_id":"0015043"}}}


id: MONDO:0000579
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete coronin-1A deficiency (obsolete MONDO:0000579)","termid":"MONDO:0000579","xrefs":{"Monarch":{"xref_id":"0000579"}}}


id: SO:0001045
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A MGE region consisting of two fused plasmids resulting from a replicative transposition event.","definition_xrefs":["phigo:at"],"direct_ancestors":[{"relation_name":"is_a","term_name":"integrated_mobile_genetic_element","termid":"SO:0001039"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cointegrated_plasmid","synonyms":[{"name":"cointegrated plasmid","type":"exact"},{"name":"cointegrated replicon","type":"exact"}],"termid":"SO:0001045"}


id: PBO:0047621
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fidgetin, microtubule severing factor","termid":"PBO:0047621"}


id: GO:0070081
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.","definition_xrefs":["GOC:mg2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transport vesicle","termid":"GO:0030133"},{"relation_name":"is_a","term_name":"clathrin-sculpted vesicle","termid":"GO:0060198"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0031410"],"is_obsolete":false,"name":"clathrin-sculpted monoamine transport vesicle","synonyms":[{"name":"clathrin sculpted monoamine constitutive secretory pathway transport vesicle","type":"exact"},{"name":"clathrin sculpted monoamine transport vesicle","type":"exact"}],"termid":"GO:0070081"}


id: PBO:0011060
data:
  {"annotation_feature_type":"gene","cv_name":"feature_relationshipprop_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"curator","termid":"PBO:0011060"}


id: PBO:0084076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTP binding protein (mammalian Ranp homolog); involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); not required for viability; protein abundance increases in response to DNA replication stress; GSP2 has a paralog, GSP1, that arose from the whole genome duplication","termid":"PBO:0084076"}


id: GO:1901102
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of gramicidin S.","definition_xrefs":["UniPathway:UPA00102","GOC:TermGenie","GOC:yaf"],"gene_count":0,"genotype_count":0,"name":"obsolete gramicidin S catabolic process (obsolete GO:1901102)","synonyms":[{"name":"gramicidin S breakdown","type":"exact"},{"name":"gramicidin S catabolism","type":"exact"},{"name":"gramicidin S degradation","type":"exact"}],"termid":"GO:1901102"}


id: MONDO:0044873
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An uncommon hematologic malignancy occurring during childhood. Many of the morphologic, immunophenotypic, and genetic changes seen in adult myelodysplastic syndromes are also observed in the childhood variants of the disease. Children present with neutropenia and thrombocytopenia more often than adults, and bone marrow hypocellularity is more often seen in children than adults.","definition_xrefs":["NCIT:C68744"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myelodysplastic syndrome","termid":"MONDO:0018881"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"childhood myelodysplastic syndrome","secondary_identifiers":["NANDO:2100003","NANDO:2200019","UMLS:C2347761","MEDGEN:389541"],"synonyms":[{"name":"childhood MDS","type":"exact"},{"name":"childhood myelodysplastic syndrome","type":"exact"},{"name":"myelodysplastic syndrome","type":"broad"}],"termid":"MONDO:0044873","xrefs":{"Monarch":{"xref_id":"0044873"}}}


id: PR:O14264
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- dfg10 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O14264"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C7D4.09c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC7D4.09c","synonyms":[{"name":"Spom972h-dfg10","type":"exact"}],"termid":"PR:O14264"}


id: MONDO:0017469
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital elbow dislocation","secondary_identifiers":["GARD:21210","UMLS:C0265561","Orphanet:295032","icd11.foundation:1593186141","MEDGEN:539330"],"synonyms":[{"name":"congenital radial head dislocation","type":"exact"},{"name":"isolated congenital elbow dislocation","type":"exact"},{"name":"isolated congenital radial head dislocation","type":"related"}],"termid":"MONDO:0017469","xrefs":{"Monarch":{"xref_id":"0017469"}}}


id: MONDO:0009105
data:
  {"annotated_genes":["SJAG_03805","SJAG_04118"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86782],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024541"},{"annotations":[86633],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013818"}]},"cv_name":"mondo","definition":"A severe congenital enteropathy manifesting as intractable diarrhea in the first month of life with failure to thrive and associated with facial dysmorphism, hair abnormalities, and, in some cases, immune disorders and intrauterine growth restriction.","definition_xrefs":["Orphanet:84064"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn error of immunity","termid":"MONDO:0003778"},{"relation_name":"is_a","term_name":"intestinal disorder","termid":"MONDO:0005020"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"type 1 interferonopathy of childhood","termid":"MONDO:0957408"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03805":null,"SJAG_04118":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004335"],"is_obsolete":false,"name":"trichohepatoenteric syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:347405","SCTID:703406006","GARD:5258","DOID:0111414","OMIMPS:222470","icd11.foundation:1470910753","UMLS:C1857276"],"synonyms":[{"name":"SD/THE","type":"exact"},{"name":"Syndromatic diarrhea","type":"related"},{"name":"Syndromatic diarrhoea","type":"related"},{"name":"THES1","type":"related"},{"name":"Tricho-hepato-enteric syndrome","type":"exact"},{"name":"Trichohepatoenteric syndrome","type":"exact"},{"name":"Trichohepatoenteric syndrome type 1","type":"exact"},{"name":"phenotypic diarrhea","type":"exact"},{"name":"phenotypic diarrhoea","type":"exact"},{"name":"syndromic diarrhea","type":"exact"},{"name":"syndromic diarrhea/Tricho-hepato-enteric syndrome","type":"exact"},{"name":"syndromic diarrhoea","type":"exact"}],"termid":"MONDO:0009105","terms_by_termid":{"MONDO:0013818":null,"MONDO:0024541":null},"xrefs":{"Monarch":{"xref_id":"0009105"}}}


id: PR:P87060
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- pop1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P87060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat-containing protein pop1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1718.01","synonyms":[{"name":"Spom972h-pop1","type":"exact"},{"name":"WD repeat-containing protein ste16 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P87060"}


id: FYPO:0004639
data:
  {"alleles_by_uniquename":{"SJAG_00028:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00028","name":"rga6delta","uniquename":"SJAG_00028:allele-1"},"SJAG_00118:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00118","name":"mid2delta","uniquename":"SJAG_00118:allele-1"},"SJAG_00266:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00266","name":"atf1delta","uniquename":"SJAG_00266:allele-1"},"SJAG_00426:allele-1":{"allele_type":"amino_acid_mutation","description":"P363S","gene_uniquename":"SJAG_00426","name":"bbl1-P363S","uniquename":"SJAG_00426:allele-1"},"SJAG_00514:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00514","name":"scd1delta","uniquename":"SJAG_00514:allele-1"},"SJAG_01143:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01143","name":"mid1delta","uniquename":"SJAG_01143:allele-1"},"SJAG_01745:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01745","name":"lem2delta","uniquename":"SJAG_01745:allele-1"},"SJAG_01794:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01794","name":"scd2delta","uniquename":"SJAG_01794:allele-1"},"SJAG_01834:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01834","name":"pom152delta","uniquename":"SJAG_01834:allele-1"},"SJAG_01906:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01906","name":"nem1delta","uniquename":"SJAG_01906:allele-1"},"SJAG_01956:allele-1":{"allele_type":"amino_acid_mutation","description":"E405K ts","gene_uniquename":"SJAG_01956","name":"nuc2-1051","uniquename":"SJAG_01956:allele-1"},"SJAG_02013:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02013","name":"pyp1delta","uniquename":"SJAG_02013:allele-1"},"SJAG_02392:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02392","name":"pom1delta","uniquename":"SJAG_02392:allele-1"},"SJAG_02592:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02592","name":"sty1delta","uniquename":"SJAG_02592:allele-1"},"SJAG_02621:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02621","name":"ago1delta","uniquename":"SJAG_02621:allele-1"},"SJAG_02763:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02763","name":"ned1delta","uniquename":"SJAG_02763:allele-1"},"SJAG_02763:allele-2":{"allele_type":"amino_acid_mutation","description":"D422E,D424E","gene_uniquename":"SJAG_02763","name":"ned1cat","synonyms":[{"name":"Catalytic mutant","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-2"},"SJAG_02763:allele-4":{"allele_type":"amino_acid_mutation","description":"S235E; S651E","gene_uniquename":"SJAG_02763","name":"ned1S235E/S651E","synonyms":[{"name":"phosphomimetic","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-4"},"SJAG_02763:allele-5":{"allele_type":"amino_acid_mutation","description":"S499E; S538E; T620E; T638E; S651E","gene_uniquename":"SJAG_02763","name":"ned1-5E","uniquename":"SJAG_02763:allele-5"},"SJAG_02819:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02819","name":"efc25delta","uniquename":"SJAG_02819:allele-1"},"SJAG_03048:allele-1":{"allele_type":"amino_acid_mutation","description":"G146D","gene_uniquename":"SJAG_03048","name":"cdc2-1w","uniquename":"SJAG_03048:allele-1"},"SJAG_03118:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03118","name":"leo1delta","uniquename":"SJAG_03118:allele-1"},"SJAG_03351:allele-1":{"allele_type":"amino_acid_mutation","description":"A186T ts","gene_uniquename":"SJAG_03351","name":"cut23-415","uniquename":"SJAG_03351:allele-1"},"SJAG_03449:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03449","name":"man1delta","uniquename":"SJAG_03449:allele-1"},"SJAG_03449:allele-2":{"allele_type":"partial_amino_acid_deletion","description":"man1DHEH","gene_uniquename":"SJAG_03449","name":"Man1DHEH","uniquename":"SJAG_03449:allele-2"},"SJAG_03449:allele-3":{"allele_type":"amino_acid_insertion_and_deletion","description":"man1-1-488","gene_uniquename":"SJAG_03449","name":"man1-1-488","uniquename":"SJAG_03449:allele-3"},"SJAG_03453:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03453","name":"ras1delta","uniquename":"SJAG_03453:allele-1"},"SJAG_03575:allele-1":{"allele_type":"amino_acid_mutation","description":"E548K 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id: GO:0006584
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.","definition_xrefs":["GOC:jl","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biogenic amine metabolic process","termid":"GO:0006576"},{"relation_name":"is_a","term_name":"catechol-containing compound metabolic process","termid":"GO:0009712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"catecholamine metabolic process","synonyms":[{"name":"catecholamine metabolism","type":"exact"}],"termid":"GO:0006584"}


id: FYPO:0007688
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during metaphase of the first meiotic nuclear division.","definition_xrefs":["PomBase:mah","PMID:16541024"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to kinetochore during meiosis I","termid":"FYPO:0004763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to kinetochore during meiotic metaphase I","synonyms":[{"name":"abolished protein localisation to kinetochore during meiotic metaphase I","type":"exact"},{"name":"abolished protein localization to kinetochore during meiosis I metaphase","type":"exact"},{"name":"protein localization to kinetochore abolished during meiotic metaphase I","type":"exact"}],"termid":"FYPO:0007688"}


id: PBO:0001448
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonuclease H2 complex subunit Rnh201 (predicted)","termid":"PBO:0001448"}


id: MONDO:0010130
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Dihydropyrimidine dehydrogenase (DPD) deficiency isaconditionin which the body cannot break down the nucleotides thymine and uracil. DPD deficiency can have a wide range of severity; some individuals may have various neurological problems, while others have no signsand symptoms. Signs and symptoms in severely affected individuals begin in infancy and may include seizures, intellectual disability, microcephaly, increased muscle tone (hypertonia), delayed motor skills, and autistic behavior. All individuals with the condition, regardless of the presence or severity of symptoms, are at risk for severe, toxic reactions to drugs called fluoropyrimidines which are used to treat cancer. Individuals with no symptoms may be diagnosed only by laboratory testing or after exposure to fluoropyrimidines. DPD deficiency is caused by mutations in the DPYD gene and is inherited in an autosomal recessive manner.","direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondrosis","termid":"MONDO:0018381"},{"relation_name":"is_a","term_name":"osteonecrosis of genetic origin","termid":"MONDO:0018383"},{"relation_name":"is_a","term_name":"inborn disorder of pyrimidine metabolism","termid":"MONDO:0019238"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0019254"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0019254"],"is_obsolete":false,"name":"dihydropyrimidine dehydrogenase deficiency","secondary_identifiers":["UMLS:C1959620","DOID:14218","GARD:19","ICD9:277.2","MESH:D054067","NCIT:C84672","OMIM:274270","MedDRA:10052622","Orphanet:1675","MEDGEN:409522","SCTID:77365006","icd11.foundation:701689290"],"synonyms":[{"name":"DPD deficiency","type":"related"},{"name":"DYPD deficiency","type":"exact"},{"name":"Dpyd deficiency","type":"related"},{"name":"dihydropyrimidine dehydrogenase deficiency","type":"exact"},{"name":"dihydrouracil dehydrogenase deficiency","type":"exact"},{"name":"familial pyrimidinaemia","type":"exact"},{"name":"familial pyrimidinemia","type":"exact"},{"name":"hereditary thymine-uraciluria","type":"related"},{"name":"pyrimidinemia, familial","type":"related"},{"name":"thymine-Uraciluria, hereditary","type":"related"},{"name":"thymine-uracilurea","type":"exact"}],"termid":"MONDO:0010130","xrefs":{"Monarch":{"xref_id":"0010130"}}}


id: GO:0043902
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of multi-organism process (obsolete GO:0043902)","termid":"GO:0043902"}


id: PBO:0049290
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutathione S-transferase alpha 9, pseudogene","termid":"PBO:0049290"}


id: PBO:0051315
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin kappa variable 1/OR2-108 (non-functional)","termid":"PBO:0051315"}


id: GO:1905608
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of presynapse assembly.","definition_xrefs":["GO_REF:0000058","GOC:PARL","GOC:TermGenie","PMID:25533483","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cellular component organization","termid":"GO:0051130"},{"relation_name":"is_a","term_name":"regulation of presynapse assembly","termid":"GO:1905606"},{"relation_name":"positively_regulates","term_name":"presynapse assembly","termid":"GO:0099054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"positive regulation of presynapse assembly","synonyms":[{"name":"activation of presynapse assembly","type":"narrow"},{"name":"activation of presynapse biogenesis","type":"narrow"},{"name":"activation of presynaptic terminal assembly","type":"narrow"},{"name":"positive regulation of presynapse biogenesis","type":"exact"},{"name":"positive regulation of presynaptic terminal assembly","type":"exact"},{"name":"up regulation of presynapse assembly","type":"exact"},{"name":"up regulation of presynapse biogenesis","type":"exact"},{"name":"up regulation of presynaptic terminal assembly","type":"exact"},{"name":"up-regulation of presynapse assembly","type":"exact"},{"name":"up-regulation of presynapse biogenesis","type":"exact"},{"name":"up-regulation of presynaptic terminal assembly","type":"exact"},{"name":"upregulation of presynapse assembly","type":"exact"},{"name":"upregulation of presynapse biogenesis","type":"exact"},{"name":"upregulation of presynaptic terminal assembly","type":"exact"}],"termid":"GO:1905608"}


id: PBO:0078901
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gln (CTG) 10-1","termid":"PBO:0078901"}


id: PBO:0079247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetratricopeptide repeat domain 21B","termid":"PBO:0079247"}


id: GO:0032641
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein metabolic process","termid":"GO:0019538"},{"relation_name":"is_a","term_name":"tumor necrosis factor superfamily cytokine production","termid":"GO:0071706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"lymphotoxin A production","secondary_identifiers":["GO:0042109"],"synonyms":[{"name":"LTA production","type":"exact"},{"name":"TNF-B production","type":"exact"},{"name":"TNF-beta production","type":"exact"},{"name":"lymphotoxin A biosynthetic process","type":"narrow"},{"name":"lymphotoxin A formation","type":"related"},{"name":"lymphotoxin A synthesis","type":"narrow"},{"name":"lymphotoxin-alpha production","type":"exact"},{"name":"tumor necrosis factor-beta production","type":"exact"}],"termid":"GO:0032641"}


id: PBO:0005494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Jmjc domain chromatin associated protein Epe1","termid":"PBO:0005494"}


id: PBO:0077162
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TLE family member 3, transcriptional corepressor","termid":"PBO:0077162"}


id: PBO:0044778
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DExD/H-box helicase 60","termid":"PBO:0044778"}


id: PBO:0018112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hexose transmembrane transporter Ght1","termid":"PBO:0018112"}


id: PBO:0067781
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 82","termid":"PBO:0067781"}


id: GO:0046905
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate.","definition_xrefs":["RHEA:34475","PMID:12641468"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prenyltransferase activity","termid":"GO:0004659"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016765"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016765","GO:0003674","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"15-cis-phytoene synthase activity","secondary_identifiers":["MetaCyc:RXN-13323","EC:2.5.1.32"],"synonyms":[{"name":"PSase activity","type":"exact"},{"name":"geranylgeranyl-diphosphate geranylgeranyltransferase activity","type":"exact"},{"name":"geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene-forming) activity","type":"exact"},{"name":"phytoene synthase activity","type":"exact"},{"name":"prephytoene-diphosphate synthase activity","type":"exact"}],"termid":"GO:0046905"}


id: PBO:0081205
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger with KRAB and SCAN domains 7","termid":"PBO:0081205"}


id: PBO:0031120
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_spontaneous_diploidization","termid":"PBO:0031120"}


id: PR:O74446
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sif2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74446"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sad1-interacting factor 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC16C4.01","synonyms":[{"name":"Spom972h-sif2","type":"exact"},{"name":"sporulation protein sif2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74446"}


id: PBO:0030527
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_chromatin","termid":"PBO:0030527"}


id: GO:0019544
data:
  {"annotated_genes":["SJAG_00495"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[78645],"is_not":false,"summary":null,"term":"GO:0019544"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arginine catabolic process","termid":"GO:0006527"},{"relation_name":"is_a","term_name":"glutamate metabolic process","termid":"GO:0006536"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00495":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0006520","GO:0008150"],"is_obsolete":false,"name":"arginine catabolic process to glutamate","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"arginine breakdown to glutamate","type":"exact"},{"name":"arginine degradation to glutamate","type":"exact"}],"termid":"GO:0019544","terms_by_termid":{"GO:0019544":null}}


id: PATO:0001904
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A directional quality inhering in a bearer by virtue of the bearer's direction approximating the shape of a circle.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"direction","termid":"PATO:0000039"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"circling direction","termid":"PATO:0001904"}


id: GO:0009490
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete mononuclear iron electron carrier (obsolete GO:0009490)","synonyms":[{"name":"mononuclear iron electron carrier","type":"exact"}],"termid":"GO:0009490"}


id: PBO:0057343
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 527","termid":"PBO:0057343"}


id: PBO:0034198
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_ohnology_relationship_with","termid":"PBO:0034198"}


id: MONDO:0019791
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"ataxia neuropathy spectrum","termid":"MONDO:0016798"},{"relation_name":"is_a","term_name":"autosomal recessive metabolic cerebellar ataxia","termid":"MONDO:0020044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0004069","MONDO:0005066","MONDO:0006025"],"is_obsolete":false,"name":"recessive mitochondrial ataxia syndrome","secondary_identifiers":["MEDGEN:1683676","Orphanet:94125","UMLS:C4760799","GARD:19251"],"synonyms":[{"name":"MIRAS","type":"exact"}],"termid":"MONDO:0019791","xrefs":{"Monarch":{"xref_id":"0019791"}}}


id: GO:0035669
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.","definition_xrefs":["PMID:14556004","GOC:BHF","PMID:18297073"],"direct_ancestors":[{"relation_name":"is_a","term_name":"toll-like receptor 4 signaling pathway","termid":"GO:0034142"},{"relation_name":"is_a","term_name":"TRAM-dependent toll-like receptor signaling pathway","termid":"GO:0035668"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"TRAM-dependent toll-like receptor 4 signaling pathway","synonyms":[{"name":"TRAM-dependent TLR4 signaling pathway","type":"exact"},{"name":"TRAM-dependent toll-like receptor 4 signalling pathway","type":"exact"}],"termid":"GO:0035669"}


id: PBO:0039522
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ANKRD33B pseudogene 3","termid":"PBO:0039522"}


id: PBO:0076214
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sad1 and UNC84 domain containing 1","termid":"PBO:0076214"}


id: MONDO:1012443
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"malignant melanoma, non-human animal","termid":"MONDO:1011821"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malignant melanoma, lion","secondary_identifiers":["OMIA:001724-9689"],"termid":"MONDO:1012443","xrefs":{"Monarch":{"xref_id":"1012443"}}}


id: MONDO:1011207
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hypophosphatasia that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypophosphatasia, non-human animal","termid":"MONDO:1010316"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypophosphatasia, dog","secondary_identifiers":["OMIA:002162-9615"],"termid":"MONDO:1011207","xrefs":{"Monarch":{"xref_id":"1011207"}}}


id: GO:1901112
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of actinorhodin.","definition_xrefs":["GOC:TermGenie","UniPathway:UPA00173","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dicarboxylic acid biosynthetic process","termid":"GO:0043650"},{"relation_name":"is_a","term_name":"actinorhodin metabolic process","termid":"GO:1901110"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"actinorhodin biosynthetic process","synonyms":[{"name":"actinorhodin anabolism","type":"exact"},{"name":"actinorhodin biosynthesis","type":"exact"},{"name":"actinorhodin formation","type":"exact"},{"name":"actinorhodin synthesis","type":"exact"}],"termid":"GO:1901112"}


id: GO:0009081
data:
  {"annotated_genes":["SJAG_00830","SJAG_04149","SJAG_00107","SJAG_03562","SJAG_04098","SJAG_00944","SJAG_03985","SJAG_02841","SJAG_00396","SJAG_03243","SJAG_06635"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104092,111405,91025,113560,108627,103608,110743],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901705"},{"annotations":[77296,59354,113561,75181,80294,103609,91026],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009098"},{"annotations":[111406],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006551"},{"annotations":[76454,77346,80295,58687,64047],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009099"},{"annotations":[73441],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006574"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid metabolic process","termid":"GO:0006520"},{"relation_name":"is_a","term_name":"carboxylic acid metabolic process","termid":"GO:0019752"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00107":null,"SJAG_00396":null,"SJAG_00830":null,"SJAG_00944":null,"SJAG_02841":null,"SJAG_03243":null,"SJAG_03562":null,"SJAG_03985":null,"SJAG_04098":null,"SJAG_04149":null,"SJAG_06635":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"branched-chain amino acid metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"synonyms":[{"name":"branched chain family amino acid metabolism","type":"exact"}],"termid":"GO:0009081","terms_by_termid":{"GO:0006551":null,"GO:0006574":null,"GO:0009098":null,"GO:0009099":null,"GO:1901705":null}}


id: PBO:0050811
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HUS1 checkpoint clamp component B","termid":"PBO:0050811"}


id: GO:0002660
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of tolerance induction dependent upon immune response","termid":"GO:0002654"},{"relation_name":"is_a","term_name":"regulation of peripheral tolerance induction","termid":"GO:0002658"},{"relation_name":"positively_regulates","term_name":"peripheral tolerance induction","termid":"GO:0002465"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of peripheral tolerance induction","synonyms":[{"name":"activation of peripheral tolerance induction","type":"narrow"},{"name":"stimulation of peripheral tolerance induction","type":"narrow"},{"name":"up regulation of peripheral tolerance induction","type":"exact"},{"name":"up-regulation of peripheral tolerance induction","type":"exact"},{"name":"upregulation of peripheral tolerance induction","type":"exact"}],"termid":"GO:0002660"}


id: PBO:0077784
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA topoisomerase I pseudogene 2","termid":"PBO:0077784"}


id: MONDO:0600019
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any acinar dysplasia in which the cause of the disease is a mutation in the TBX4 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"acinar dysplasia","termid":"MONDO:0600016"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acinar dysplasia caused by mutation in TBX4","synonyms":[{"name":"TBX4 acinar dysplasia","type":"exact"},{"name":"TBX4 related acinar dysplasia","type":"exact"}],"termid":"MONDO:0600019","xrefs":{"Monarch":{"xref_id":"0600019"}}}


id: GO:0003957
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NADPH + NAD+ = NADP+ + NADH.","definition_xrefs":["RHEA:11692"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on NAD(P)H as acceptor","termid":"GO:0016652"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"NAD(P)+ transhydrogenase (Si-specific) activity","secondary_identifiers":["EC:1.6.1.1","Reactome:R-HSA-450971"],"synonyms":[{"name":"H+-thase","type":"broad"},{"name":"NAD transhydrogenase","type":"broad"},{"name":"NAD(P) transhydrogenase (B-specific) activity","type":"exact"},{"name":"NAD(P)+ transhydrogenase (B-specific) activity","type":"exact"},{"name":"NADH transhydrogenase","type":"broad"},{"name":"NADH-NADP-transhydrogenase","type":"broad"},{"name":"NADPH-NAD oxidoreductase","type":"broad"},{"name":"NADPH-NAD transhydrogenase","type":"broad"},{"name":"NADPH:NAD+ oxidoreductase (B-specific)","type":"related"},{"name":"NADPH:NAD+ transhydrogenase","type":"broad"},{"name":"nicotinamide adenine dinucleotide (phosphate) transhydrogenase","type":"broad"},{"name":"nicotinamide nucleotide transhydrogenase activity","type":"broad"},{"name":"non-energy-linked transhydrogenase activity","type":"related"},{"name":"pyridine nucleotide transferase","type":"broad"},{"name":"pyridine nucleotide transhydrogenase activity","type":"broad"}],"termid":"GO:0003957"}


id: GO:0070257
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of secretion","termid":"GO:0051047"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"is_a","term_name":"regulation of mucus secretion","termid":"GO:0070255"},{"relation_name":"positively_regulates","term_name":"mucus secretion","termid":"GO:0070254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of mucus secretion","synonyms":[{"name":"positive regulation of mucus production","type":"exact"}],"termid":"GO:0070257"}


id: GO:0018184
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of a protein amino acid by polyamination.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification process","termid":"GO:0036211"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein polyamination","synonyms":[{"name":"protein amino acid polyamination","type":"exact"}],"termid":"GO:0018184"}


id: GO:0080006
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pattern specification process","termid":"GO:0007389"},{"relation_name":"part_of","term_name":"shoot system development","termid":"GO:0048367"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"internode patterning","termid":"GO:0080006"}


id: GO:0021594
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.","definition_xrefs":["GOC:cls","GOC:jid","GO_REF:0000021","GOC:dgh","GOC:dph","ISBN:0838580343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"rhombomere morphogenesis","termid":"GO:0021593"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"rhombomere formation","termid":"GO:0021594"}


id: GO:0003273
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell migration involved in heart development","termid":"GO:0060973"},{"relation_name":"part_of","term_name":"endocardial cushion formation","termid":"GO:0003272"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cell migration involved in endocardial cushion formation","termid":"GO:0003273"}


id: GO:0086095
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate.","definition_xrefs":["Wikipedia:G_protein-gated_ion_channel","GOC:BHF","GOC:mtg_cardiac_conduct_nov11"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate (obsolete GO:0086095)","synonyms":[{"name":"Gbeta/gamma-coupled muscarinic receptor signaling pathway involved in negative regulation of heart rate","type":"related"},{"name":"cardiac muscarinic receptor signaling via Gbeta/gamma","type":"related"},{"name":"muscarinic receptor signaling pathway involved in activation of IKACH","type":"exact"},{"name":"muscarinic receptor signaling pathway involved in ion channel activation","type":"broad"},{"name":"positive regulation of IKACh channel activity by G-protein coupled acetylcholine receptor signaling","type":"exact"}],"termid":"GO:0086095"}


id: PBO:0077867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tropomyosin 3 pseudogene 8","termid":"PBO:0077867"}


id: GO:0070903
data:
  {"annotated_genes":["SJAG_04113","SJAG_00358"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94604,117259],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990799"}]},"cv_name":"biological_process","definition":"The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.","definition_xrefs":["GOC:mcc","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA thio-modification","termid":"GO:0034227"},{"relation_name":"is_a","term_name":"mitochondrial tRNA modification","termid":"GO:0070900"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00358":null,"SJAG_04113":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0140053"},{"rel_name":"is_a","termid":"GO:0006399"}],"interesting_parent_ids":["GO:0006399","GO:0010467","GO:0140053","GO:0008150"],"is_obsolete":false,"name":"mitochondrial tRNA thio-modification","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0070903","terms_by_termid":{"GO:1990799":null}}


id: MONDO:0020632
data:
  {"annotated_genes":["SJAG_01471"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86890],"is_not":false,"summary":null,"term":"MONDO:0020632"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete epileptic encephalopathy, infantile or early childhood (obsolete MONDO:0020627)","termid":"MONDO:0020627"},{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01471":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027","MONDO:0700092"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy 93","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1642888","UMLS:C4693934","DOID:0112275","OMIM:618012","GARD:16285"],"synonyms":[{"name":"DEE93","type":"exact"},{"name":"IECEE3","type":"exact"},{"name":"developmental and epileptic encephalopathy 93","type":"exact"},{"name":"epileptic encephalopathy, infantile or early childhood, 3","type":"exact"}],"termid":"MONDO:0020632","terms_by_termid":{"MONDO:0020632":null},"xrefs":{"Monarch":{"xref_id":"0020632"}}}


id: PBO:0052795
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 35","termid":"PBO:0052795"}


id: GO:0021613
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial ophthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.","definition_xrefs":["GOC:dgh","ISBN:0838580343","GOC:dph","GO_REF:0000021","GOC:cls","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve maturation","termid":"GO:0021605"},{"relation_name":"part_of","term_name":"facial nerve development","termid":"GO:0021561"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"facial nerve maturation","synonyms":[{"name":"CN VII maturation","type":"related"}],"termid":"GO:0021613"}


id: PBO:0042555
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin dependent kinase 18","termid":"PBO:0042555"}


id: MONDO:1012068
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"dystrophic epidermolysis bullosa, non-human animal","termid":"MONDO:1011737"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dystrophic epidermolysis bullosa, dog","secondary_identifiers":["OMIA:000341-9615"],"termid":"MONDO:1012068","xrefs":{"Monarch":{"xref_id":"1012068"}}}


id: GO:0018623
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.","definition_xrefs":["EC:1.14.12.10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor","termid":"GO:0016708"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"benzoate 1,2-dioxygenase activity","secondary_identifiers":["UM-BBD_enzymeID:r0245","MetaCyc:BENZOATE-12-DIOXYGENASE-RXN","RHEA:12633"],"synonyms":[{"name":"benzoate dioxygenase activity","type":"related"},{"name":"benzoate hydroxylase activity","type":"related"},{"name":"benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)","type":"related"},{"name":"benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)","type":"related"},{"name":"benzoic hydroxylase activity","type":"related"}],"termid":"GO:0018623"}


id: GO:0032087
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of type IV site-specific deoxyribonuclease activity (obsolete GO:0032087)","synonyms":[{"name":"regulation of type IV restriction endodeoxyribonuclease activity","type":"exact"},{"name":"type IV restriction endodeoxyribonuclease regulator","type":"related"},{"name":"type IV restriction enzyme regulator","type":"related"}],"termid":"GO:0032087"}


id: PBO:0004212
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by S. cerevisiae SIC1","termid":"PBO:0004212"}


id: GO:0071353
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to interleukin-4","termid":"GO:0070670"},{"relation_name":"is_a","term_name":"cellular response to cytokine stimulus","termid":"GO:0071345"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to interleukin-4","synonyms":[{"name":"cellular response to IL-4","type":"exact"}],"termid":"GO:0071353"}


id: PBO:0082969
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity; required for normal intracellular accumulation of glycogen; phosphorylated in vivo; expression increases during wine fermentation; protein abundance increases in response to DNA replication stress; IGD1 has a paralog, YOL024W, that arose from the whole genome duplication","termid":"PBO:0082969"}


id: MONDO:0000426
data:
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  {"annotated_genes":["SJAG_03163","SJAG_01671","SJAG_01895","SJAG_02398","SJAG_03920","SJAG_00260"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86197],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008192"},{"annotations":[87372],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011121"},{"annotations":[87282],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011544"},{"annotations":[85986],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007273"},{"annotations":[86194],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013602"},{"annotations":[87518],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032771"}]},"cv_name":"mondo","definition":"Benign and malignant neoplasms which arise from or directly involve the central or peripheral elements of the autonomic nervous system.","definition_xrefs":["NCIT:C5112"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autonomic nervous system disorder","termid":"MONDO:0001292"},{"relation_name":"is_a","term_name":"peripheral nervous system neoplasm","termid":"MONDO:0001406"},{"relation_name":"is_a","term_name":"central nervous system neoplasm","termid":"MONDO:0006130"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00260":null,"SJAG_01671":null,"SJAG_01895":null,"SJAG_02398":null,"SJAG_03163":null,"SJAG_03920":null},"genotype_count":0,"is_obsolete":false,"name":"autonomic nervous system neoplasm","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1332356","DOID:2621","MEDGEN:231389"],"synonyms":[{"name":"autonomic nervous system neoplasm","type":"exact"},{"name":"autonomic nervous system neoplasm (disease)","type":"exact"},{"name":"autonomic nervous system neoplasms","type":"exact"},{"name":"autonomic nervous system tumor","type":"exact"},{"name":"autonomic nervous system tumour","type":"exact"},{"name":"neoplasm of autonomic nervous system","type":"exact"},{"name":"neoplasm of the autonomic nervous system","type":"exact"},{"name":"tumor of autonomic nervous system","type":"exact"},{"name":"tumor of the autonomic nervous system","type":"exact"},{"name":"tumour of autonomic nervous system","type":"exact"},{"name":"tumour of the autonomic nervous system","type":"exact"}],"termid":"MONDO:0002366","terms_by_termid":{"MONDO:0007273":null,"MONDO:0008192":null,"MONDO:0011121":null,"MONDO:0011544":null,"MONDO:0013602":null,"MONDO:0032771":null},"xrefs":{"Monarch":{"xref_id":"0002366"}}}


id: PBO:0089126
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U5 snRNP-associated protein Aar2","termid":"PBO:0089126"}


id: GO:0008733
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-arabinose = L-ribulose.","definition_xrefs":["RHEA:14821","EC:5.3.1.4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, interconverting aldoses and ketoses","termid":"GO:0016861"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016853","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"L-arabinose isomerase activity","secondary_identifiers":["MetaCyc:ARABISOM-RXN","KEGG_REACTION:R01761"],"synonyms":[{"name":"L-arabinose aldose-ketose-isomerase activity","type":"related"},{"name":"L-arabinose ketol-isomerase activity","type":"related"}],"termid":"GO:0008733"}


id: GO:0018695
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.","definition_xrefs":["EC:1.17.9.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on CH or CH2 groups","termid":"GO:0016725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"4-cresol dehydrogenase (hydroxylating) activity","secondary_identifiers":["MetaCyc:1.17.99.1-RXN","UM-BBD_reactionID:r0272","RHEA:15141"],"synonyms":[{"name":"4-cresol dehydrogenase activity","type":"exact"},{"name":"4-cresol:acceptor oxidoreductase (methyl-hydroxylating)","type":"related"},{"name":"p-cresol methylhydroxylase activity","type":"related"},{"name":"p-cresol-(acceptor) oxidoreductase (hydroxylating) activity","type":"related"}],"termid":"GO:0018695"}


id: SO:0002258
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A binding motif with the consensus sequence TTAGGG to which Teb1 binds.","definition_xrefs":["PMID:27901072","PMID:23314747"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA_motif","termid":"SO:0000713"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"teb1_recognition_motif","synonyms":[{"name":"teb1 recognition motif","type":"exact"}],"termid":"SO:0002258"}


id: GO:0016495
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.","definition_xrefs":["GOC:signaling","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chemokine receptor activity","termid":"GO:0004950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"C-X3-C chemokine receptor activity","termid":"GO:0016495"}


id: MONDO:0013626
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any psoriasis in which the cause of the disease is a mutation in the IL36RN gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete unclassified genetic skin disorder (obsolete MONDO:0019299)","termid":"MONDO:0019299"},{"relation_name":"is_a","term_name":"psoriasis","termid":"MONDO:0005083"},{"relation_name":"is_a","term_name":"epidermal disease","termid":"MONDO:0019268"},{"relation_name":"is_a","term_name":"autoinflammatory syndrome","termid":"MONDO:0019751"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005093"],"is_obsolete":false,"name":"psoriasis 14, pustular","secondary_identifiers":["NCIT:C119057","DOID:0080474","GARD:17679","MEDGEN:581114","Orphanet:404546","ICD9:696.1","Orphanet:163931","OMIM:614204","NANDO:1200244","NANDO:2200452","SCTID:238612002","SCTID:83839005","UMLS:C0392439"],"synonyms":[{"name":"DITRA","type":"exact"},{"name":"GPP","type":"related"},{"name":"IL36RN psoriasis","type":"exact"},{"name":"Interleukin 36 receptor antagonist deficiency","type":"exact"},{"name":"PSORP","type":"exact"},{"name":"PSORS14","type":"exact"},{"name":"acrodermatitis continua of Hallopeau","type":"exact"},{"name":"acrodermatitis continua suppurativa of Hallopeau","type":"exact"},{"name":"deficiency of IL-36R antagonist","type":"exact"},{"name":"deficiency of IL-36Ra","type":"exact"},{"name":"deficiency of the interleukin-36 receptor antagonist","type":"exact"},{"name":"familial generalised pustular psoriasis","type":"exact"},{"name":"familial generalized pustular psoriasis","type":"exact"},{"name":"generalised pustular psoriasis","type":"related"},{"name":"generalized pustular psoriasis","type":"related"},{"name":"palmoplantar pustulosis","type":"broad"},{"name":"psoriasis 14, pustular","type":"exact"},{"name":"psoriasis caused by mutation in IL36RN","type":"exact"}],"termid":"MONDO:0013626","xrefs":{"Monarch":{"xref_id":"0013626"}}}


id: PBO:0071294
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L26 pseudogene 17","termid":"PBO:0071294"}


id: PBO:0072789
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sarcoma antigen 4, pseudogene","termid":"PBO:0072789"}


id: PBO:0073267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"septin 7 pseudogene 11","termid":"PBO:0073267"}


id: GO:1905764
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.","definition_xrefs":["GOC:BHF","GOC:TermGenie","PMID:14690602","GO_REF:0000058","GOC:BHF_telomere","GOC:nc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of telomere capping","termid":"GO:1904353"},{"relation_name":"is_a","term_name":"regulation of telomere maintenance in response to DNA damage","termid":"GO:1904505"},{"relation_name":"regulates","term_name":"protection from non-homologous end joining at telomere","termid":"GO:0031848"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0032200"}],"interesting_parent_ids":["GO:0006259","GO:0032200","GO:0008150"],"is_obsolete":false,"name":"regulation of protection from non-homologous end joining at telomere","synonyms":[{"name":"regulation of protection from NHEJ-mediated telomere fusion","type":"exact"}],"termid":"GO:1905764"}


id: PR:O42656
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ric1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42656"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanine nucleotide exchange factor subunit ric1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1851.04c","synonyms":[{"name":"Spom972h-ric1","type":"exact"},{"name":"protein ric1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42656"}


id: PBO:0076452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TAGAP antisense RNA 1","termid":"PBO:0076452"}


id: GO:0071071
data:
  {"annotated_genes":["SJAG_03170","SJAG_01187","SJAG_01906","SJAG_02380","SJAG_00053","SJAG_03940","SJAG_02613"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[104692,90752],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902647"},{"annotations":[111680,115783],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001211"},{"annotations":[110035,113053],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071072"},{"annotations":[117835],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902648"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lipid biosynthetic process","termid":"GO:0046890"},{"relation_name":"is_a","term_name":"regulation of phospholipid metabolic process","termid":"GO:1903725"},{"relation_name":"regulates","term_name":"phospholipid biosynthetic process","termid":"GO:0008654"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00053":null,"SJAG_01187":null,"SJAG_01906":null,"SJAG_02380":null,"SJAG_02613":null,"SJAG_03170":null,"SJAG_03940":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"regulation of phospholipid biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of phospholipid anabolism","type":"exact"},{"name":"regulation of phospholipid biosynthesis","type":"exact"},{"name":"regulation of phospholipid formation","type":"exact"},{"name":"regulation of phospholipid synthesis","type":"exact"}],"termid":"GO:0071071","terms_by_termid":{"GO:0071072":null,"GO:1902647":null,"GO:1902648":null,"GO:2001211":null}}


id: PR:O74798
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC2D10.04 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74798"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arrestin-related trafficking adapter C2D10.04 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC2D10.04","synonyms":[{"name":"Spom972h-SPBC2D10.04","type":"exact"}],"termid":"PR:O74798"}


id: FYPO:0005189
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which re-entry into the mitotic cell cycle is abnormal after arrest resulting from hydroxyurea exposure.","definition_xrefs":["PomBase:mah","PMID:19546237"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic cell cycle regulation during cellular response to hydroxyurea","termid":"FYPO:0001933"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000298","FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000631"],"is_obsolete":false,"name":"abnormal re-entry into mitotic cell cycle after arrest in response to hydroxyurea","synonyms":[{"name":"abnormal re-entry into mitotic cell cycle after HU arrest","type":"exact"},{"name":"abnormal re-entry into mitotic cell cycle after arrest in response to HU","type":"exact"},{"name":"abnormal re-entry into mitotic cell cycle after arrest in response to hydroxyurea during vegetative growth","type":"exact"},{"name":"abnormal re-entry into mitotic cell cycle after hydroxyurea-induced arrest","type":"exact"}],"termid":"FYPO:0005189"}


id: FYECO:0000160
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which tacrolimus was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ tacrolimus","secondary_identifiers":["FYECO:0000029"],"synonyms":[{"name":"FK506 added","type":"exact"},{"name":"tacrolimus added","type":"exact"}],"termid":"FYECO:0000160"}


id: GO:0071852
data:
  {"annotated_genes":["SJAG_02222","SJAG_03295","SJAG_00876","SJAG_02192","SJAG_05272","SJAG_04236","SJAG_01888","SJAG_01426","SJAG_01774","SJAG_01227","SJAG_00424","SJAG_04483","SJAG_02727","SJAG_04668","SJAG_00667","SJAG_05001","SJAG_02718","SJAG_02733","SJAG_02684","SJAG_04878","SJAG_04551","SJAG_01181","SJAG_02468","SJAG_03013","SJAG_01321","SJAG_04327","SJAG_04771","SJAG_01017","SJAG_01171","SJAG_00310","SJAG_04595","SJAG_03631","SJAG_02278","SJAG_00218","SJAG_03483","SJAG_01290","SJAG_03705","SJAG_00610","SJAG_04073","SJAG_02845","SJAG_05285","SJAG_04868","SJAG_03646","SJAG_00661","SJAG_04864","SJAG_04184","SJAG_00974","SJAG_00163","SJAG_04851","SJAG_04850","SJAG_03587","SJAG_04238","SJAG_01963","SJAG_01835","SJAG_04620","SJAG_02916","SJAG_03444","SJAG_02590","SJAG_01453","SJAG_02446","SJAG_02649","SJAG_03057","SJAG_04666","SJAG_01288","SJAG_03753","SJAG_01028","SJAG_04462","SJAG_03123"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90072,92605,117761],"is_not":false,"summary":null,"term":"GO:0071852"},{"annotations":[94802],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0034413"},{"annotations":[88553,90588,89045,92110],"is_not":false,"rel_names":["part_of","is_a"],"summary":null,"term":"GO:0030476"},{"annotations":[73430],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0034412"},{"annotations":[118083,104485,109380,114387,118091],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070591"},{"annotations":[71808,79013,70985,73939,73757],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0070600"},{"annotations":[74863,76217,113470,91936,116121,73432,106424,71261],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0071970"},{"annotations":[78609,102956],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0070880"},{"annotations":[102259,108376,102260,95440],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0070879"},{"annotations":[93681,102768,79762,118208,70598,70929,71744,71109,75252,95587,100942],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009272"},{"annotations":[111624,102261,94362,108377,100470,88619,102262,89436],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904541"},{"annotations":[75632,76788,76216,102769,79868,80700,77165,75548,78175,74862,71260,71313,110357,89676,71615,78254],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031505"},{"annotations":[72821,107008],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0071966"},{"annotations":[92762,87860],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0140748"},{"annotations":[89781,103161,92768,95277],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0070610"},{"annotations":[100502,102466,93054],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0032995"},{"annotations":[111291,71916,87935],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0060237"}]},"cv_name":"biological_process","definition":"A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell wall organization or 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cell wall organization or biogenesis","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"fungal-type cell wall organisation or biogenesis","type":"exact"},{"name":"fungal-type cell wall organization and biogenesis","type":"related"}],"termid":"GO:0071852","terms_by_termid":{"GO:0009272":null,"GO:0030476":null,"GO:0031505":null,"GO:0032995":null,"GO:0034412":null,"GO:0034413":null,"GO:0060237":null,"GO:0070591":null,"GO:0070600":null,"GO:0070610":null,"GO:0070879":null,"GO:0070880":null,"GO:0071852":null,"GO:0071966":null,"GO:0071970":null,"GO:0140748":null,"GO:1904541":null}}


id: PBO:0072731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S1PR1 divergent transcript","termid":"PBO:0072731"}


id: MONDO:0033169
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"poisoning","termid":"MONDO:0029000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"curariform drugs toxicity","secondary_identifiers":["Orphanet:413693"],"termid":"MONDO:0033169","xrefs":{"Monarch":{"xref_id":"0033169"}}}


id: GO:0052846
data:
  {"annotated_genes":["SJAG_01154","SJAG_04870","SJAG_00244"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[89063,105519,115362],"is_not":false,"summary":null,"term":"GO:0052846"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 1,5-bisdiphospho-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+.","definition_xrefs":["PMID:10827188","PMID:11502751","PMID:26422458"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inositol bisdiphosphate tetrakisphosphate diphosphatase activity","termid":"GO:0052841"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00244":null,"SJAG_01154":null,"SJAG_04870":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824"],"is_obsolete":false,"name":"inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:0101012","MetaCyc:RXN-10965"],"synonyms":[{"name":"inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity","type":"exact"},{"name":"inositol 1,5-bispyrophosphate 2,3,4,6-tetrakisphosphate 1-pyrophosphatase activity","type":"exact"}],"termid":"GO:0052846","terms_by_termid":{"GO:0052846":null}}


id: MONDO:0032670
data:
  {"annotated_genes":["SJAG_01512","SJAG_03762"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86406,86407],"is_not":false,"summary":null,"term":"MONDO:0032670"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Diamond-Blackfan anemia","termid":"MONDO:0015253"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01512":null,"SJAG_03762":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"Diamond-Blackfan anemia 20","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1674961","DOID:0111891","OMIM:618313","GARD:16340","UMLS:C5193022"],"synonyms":[{"name":"DBA20","type":"related"},{"name":"DIAMOND-BLACKFAN ANEMIA 20","type":"related"}],"termid":"MONDO:0032670","terms_by_termid":{"MONDO:0032670":null},"xrefs":{"Monarch":{"xref_id":"0032670"}}}


id: FYPO:0007075
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 14 of histone H3 occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone ubiquitination during vegetative growth","termid":"FYPO:0002921"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002494","FYPO:0002274","FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"decreased histone H3-K14 ubiquitination during vegetative growth","synonyms":[{"name":"decreased histone H3-K14 ubiquitination during mitotic cell cycle","type":"related"},{"name":"decreased histone H3K14 ubiquitination during vegetative growth","type":"exact"},{"name":"reduced histone H3-K14 ubiquitination during vegetative growth","type":"exact"}],"termid":"FYPO:0007075"}


id: SO:0000769
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The region of a two-piece tmRNA that bears the reading frame encoding the proteolysis tag. The tmRNA gene undergoes circular permutation in some groups of bacteria. Processing of the transcripts from such a gene leaves the mature tmRNA in two pieces, base-paired together.","definition_xrefs":["Indiana:kw","issn:1362-4962","doi:10.1093/nar/gkh795"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tmRNA_region","termid":"SO:0000847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tmRNA_coding_piece","synonyms":[{"name":"tmRNA coding piece","type":"exact"}],"termid":"SO:0000769"}


id: FYPO:0001854
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to iron ions. All genes, or a specific subset of genes, may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased transcription during vegetative growth","termid":"FYPO:0000780"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000294"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0000294","FYPO:0006551"],"is_obsolete":false,"name":"increased transcription during cellular response to iron","synonyms":[{"name":"increased transcription during cellular response to iron during mitotic cell cycle","type":"related"},{"name":"increased transcription during cellular response to iron during vegetative growth","type":"exact"},{"name":"increased transcription during cellular response to iron ion","type":"exact"},{"name":"increased transcription during cellular response to iron ions","type":"exact"}],"termid":"FYPO:0001854"}


id: PBO:0084727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial inner membrane protein of unknown function; associates with mitochondrial ribosome; localizes to the inner membrane with the C terminus facing the intermembrane space; ortholog of human RMND1, mutation in which is implicated in infantile encephaloneuromyopathy and defective mitochondrial translation","termid":"PBO:0084727"}


id: MONDO:0008134
data:
  {"annotated_genes":["SJAG_02656"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86122],"is_not":false,"summary":null,"term":"MONDO:0008134"}]},"cv_name":"mondo","definition":"One of the most common forms of hereditary optic neuropathy characterized by progressive bilateral visual loss during the first decade of life, associated with optic disk pallor, visual field and color vision defects.","definition_xrefs":["Orphanet:98673"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"},{"relation_name":"is_a","term_name":"autosomal dominant optic atrophy","termid":"MONDO:0020250"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02656":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005559","MONDO:0005066","MONDO:0004069","MONDO:0005328","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant optic atrophy, classic form","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:9890","DOID:0111441","MEDGEN:137902","OMIM:165500","SCTID:717336005","UMLS:C0338508"],"synonyms":[{"name":"Kjer optic atrophy","type":"exact"},{"name":"Kjer-type optic atrophy","type":"related"},{"name":"OAK","type":"related"},{"name":"OPA1","type":"related"},{"name":"autosomal dominant optic atrophy, Kjer type","type":"exact"},{"name":"optic atrophy 1","type":"related"},{"name":"optic atrophy type 1","type":"exact"},{"name":"optic atrophy, Kjer type","type":"related"},{"name":"optic atrophy, juvenile","type":"related"}],"termid":"MONDO:0008134","terms_by_termid":{"MONDO:0008134":null},"xrefs":{"Monarch":{"xref_id":"0008134"}}}


id: PBO:0005356
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP-galactose transporter Gms1","termid":"PBO:0005356"}


id: MONDO:1010272
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Renal agenesis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of development or morphogenesis, non-human animal","termid":"MONDO:1011313"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"renal disease, non-human animal","termid":"MONDO:1011909"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"renal agenesis, non-human animal","secondary_identifiers":["OMIA:002007"],"termid":"MONDO:1010272","xrefs":{"Monarch":{"xref_id":"1010272"}}}


id: GO:0002768
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.","definition_xrefs":["GOC:add","ISBN:0781735149","PMID:15771571"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immune response-regulating signaling pathway","termid":"GO:0002764"},{"relation_name":"is_a","term_name":"cell surface receptor signaling pathway","termid":"GO:0007166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"immune response-regulating cell surface receptor signaling pathway","synonyms":[{"name":"immune response-regulating cell surface receptor signalling pathway","type":"exact"}],"termid":"GO:0002768"}


id: MONDO:0024746
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A teratoma composed of immature, fetal-type tissues.","definition_xrefs":["NCIT:C4286"],"direct_ancestors":[{"relation_name":"is_a","term_name":"teratoma","termid":"MONDO:0002601"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immature teratoma","secondary_identifiers":["ICDO:9080/3","NANDO:2200106","UMLS:C0334520","MEDGEN:90798"],"synonyms":[{"name":"embryonal teratoma","type":"exact"},{"name":"hrade 2 Teratoma","type":"exact"},{"name":"immature teratoma","type":"exact"}],"termid":"MONDO:0024746","xrefs":{"Monarch":{"xref_id":"0024746"}}}


id: MOD:00002
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-serine residue to O3-glycosylserine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-glycosylated residue","termid":"MOD:00396"},{"relation_name":"is_a","term_name":"modified L-serine residue","termid":"MOD:00916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"O-glycosyl-L-serine","synonyms":[{"name":"OGlycoSer","type":"exact"}],"termid":"MOD:00002"}


id: PR:O42709
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cdc23 gene.","definition_xrefs":["UniProtKB:O42709","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA replication licensing factor mcm10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1347.10","synonyms":[{"name":"Spom972h-cdc23","type":"exact"},{"name":"cdc23 protein (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"minichromosome maintenance protein 10 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42709"}


id: MONDO:0011089
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Patent ductus venosus (PDV) is an extremely rare form of congenital portosystemic shunt that results in the diversion of portal blood into the systemic circulation. Failure of DV closure after birth leads to PDV. PDV results in portal venous blood bypassing the liver and directly entering the systemic circulation, decreasing hepatic blood flow and increasing blood volume and toxic substances in the systemic circulation.","definition_xrefs":["PMID:36329968"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"congenital portosystemic shunt","termid":"MONDO:0018811"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"patent ductus venosus","secondary_identifiers":["UMLS:C0344688","MEDGEN:91033","OMIM:601466","ICD9:747.49","MESH:C562830","SCTID:253330006"],"synonyms":[{"name":"PDV","type":"related"},{"name":"PSVS","type":"related"},{"name":"patent ductus venosus","type":"exact"},{"name":"portosystemic Venous shunt, congenital","type":"related"}],"termid":"MONDO:0011089","xrefs":{"Monarch":{"xref_id":"0011089"}}}


id: GO:0009693
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.","definition_xrefs":["ISBN:0387969845"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ethylene metabolic process","termid":"GO:0009692"},{"relation_name":"is_a","term_name":"alkene biosynthetic process","termid":"GO:0043450"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ethylene biosynthetic process","secondary_identifiers":["MetaCyc:ETHYL-PWY","GO:0042456"],"synonyms":[{"name":"ethene biosynthesis","type":"exact"},{"name":"ethene biosynthesis from L-methionine","type":"exact"},{"name":"ethene biosynthetic process","type":"exact"},{"name":"ethene biosynthetic process from L-methionine","type":"exact"},{"name":"ethylene anabolism","type":"exact"},{"name":"ethylene biosynthesis","type":"exact"},{"name":"ethylene biosynthesis from L-methionine","type":"exact"},{"name":"ethylene biosynthetic process from L-methionine","type":"exact"},{"name":"ethylene formation","type":"exact"},{"name":"ethylene synthesis","type":"exact"}],"termid":"GO:0009693"}


id: GO:0071056
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.","definition_xrefs":["PMID:11882657"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"alpha9-beta1 integrin-ADAM15 complex","synonyms":[{"name":"ITGA9-ITGB1-ADAM15 complex","type":"narrow"}],"termid":"GO:0071056"}


id: GO:0004478
data:
  {"annotated_genes":["SJAG_03659"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[75504],"is_not":false,"summary":null,"term":"GO:0004478"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.","definition_xrefs":["EC:2.5.1.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase activity, transferring alkyl or aryl (other than methyl) groups","termid":"GO:0016765"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03659":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016765"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016765","GO:0016740"],"is_obsolete":false,"name":"methionine adenosyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:S-ADENMETSYN-RXN","Reactome:R-HSA-5603114","Reactome:R-HSA-174391","Reactome:R-HSA-5603087","RHEA:21080"],"synonyms":[{"name":"ATP-methionine adenosyltransferase activity","type":"related"},{"name":"ATP:L-methionine S-adenosyltransferase activity","type":"related"},{"name":"AdoMet synthetase activity","type":"related"},{"name":"S-adenosyl-L-methionine synthetase activity","type":"related"},{"name":"S-adenosylmethionine synthase activity","type":"related"},{"name":"S-adenosylmethionine synthetase activity","type":"related"},{"name":"adenosylmethionine synthetase activity","type":"related"},{"name":"methionine S-adenosyltransferase activity","type":"related"},{"name":"methionine-activating enzyme","type":"related"}],"termid":"GO:0004478","terms_by_termid":{"GO:0004478":null}}


id: GO:1905376
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity.","definition_xrefs":["GO_REF:0000059","PMID:26722473","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of cytochrome-c oxidase activity (obsolete GO:1905376)","synonyms":[{"name":"down regulation of NADH cytochrome c oxidase","type":"exact"},{"name":"down regulation of aa3-type cytochrome c oxidase","type":"narrow"},{"name":"down regulation of ba3-type cytochrome c oxidase","type":"narrow"},{"name":"down regulation of caa3-type cytochrome c oxidase","type":"narrow"},{"name":"down regulation of cbb3-type cytochrome c oxidase","type":"narrow"},{"name":"down regulation of complex IV (mitochondrial electron transport) activity","type":"related"},{"name":"down regulation of cytochrome a3 activity","type":"narrow"},{"name":"down regulation of cytochrome aa3 activity","type":"narrow"},{"name":"down regulation of cytochrome c oxidase activity","type":"exact"},{"name":"down regulation of cytochrome oxidase activity","type":"related"},{"name":"down regulation of cytochrome-c oxidase activity","type":"exact"},{"name":"down regulation of ferrocytochrome c oxidase","type":"narrow"},{"name":"down regulation of ferrocytochrome-c:oxygen oxidoreductase","type":"narrow"},{"name":"down regulation of indophenol oxidase","type":"narrow"},{"name":"down regulation of indophenolase","type":"narrow"},{"name":"down regulation of warburg's respiratory enzyme activity","type":"related"},{"name":"down-regulation of NADH cytochrome c oxidase","type":"exact"},{"name":"down-regulation of aa3-type cytochrome c oxidase","type":"narrow"},{"name":"down-regulation of ba3-type cytochrome c oxidase","type":"narrow"},{"name":"down-regulation of caa3-type cytochrome c oxidase","type":"narrow"},{"name":"down-regulation of cbb3-type cytochrome c oxidase","type":"narrow"},{"name":"down-regulation of complex IV (mitochondrial electron transport) activity","type":"related"},{"name":"down-regulation of cytochrome a3 activity","type":"narrow"},{"name":"down-regulation of cytochrome aa3 activity","type":"narrow"},{"name":"down-regulation of cytochrome c oxidase activity","type":"exact"},{"name":"down-regulation of cytochrome oxidase activity","type":"related"},{"name":"down-regulation of cytochrome-c oxidase activity","type":"exact"},{"name":"down-regulation of ferrocytochrome c oxidase","type":"narrow"},{"name":"down-regulation of ferrocytochrome-c:oxygen oxidoreductase","type":"narrow"},{"name":"down-regulation of indophenol oxidase","type":"narrow"},{"name":"down-regulation of indophenolase","type":"narrow"},{"name":"down-regulation of warburg's respiratory enzyme activity","type":"related"},{"name":"downregulation of NADH cytochrome c oxidase","type":"exact"},{"name":"downregulation of aa3-type cytochrome c oxidase","type":"narrow"},{"name":"downregulation of ba3-type cytochrome c oxidase","type":"narrow"},{"name":"downregulation of caa3-type cytochrome c oxidase","type":"narrow"},{"name":"downregulation of cbb3-type cytochrome c oxidase","type":"narrow"},{"name":"downregulation of complex IV (mitochondrial electron transport) activity","type":"related"},{"name":"downregulation of cytochrome a3 activity","type":"narrow"},{"name":"downregulation of cytochrome aa3 activity","type":"narrow"},{"name":"downregulation of cytochrome c oxidase activity","type":"exact"},{"name":"downregulation of cytochrome oxidase activity","type":"related"},{"name":"downregulation of cytochrome-c oxidase activity","type":"exact"},{"name":"downregulation of ferrocytochrome c oxidase","type":"narrow"},{"name":"downregulation of ferrocytochrome-c:oxygen oxidoreductase","type":"narrow"},{"name":"downregulation of indophenol oxidase","type":"narrow"},{"name":"downregulation of indophenolase","type":"narrow"},{"name":"downregulation of warburg's respiratory enzyme activity","type":"related"},{"name":"inhibition of NADH cytochrome c oxidase","type":"narrow"},{"name":"inhibition of aa3-type cytochrome c oxidase","type":"narrow"},{"name":"inhibition of ba3-type cytochrome c oxidase","type":"narrow"},{"name":"inhibition of caa3-type cytochrome c oxidase","type":"narrow"},{"name":"inhibition of cbb3-type cytochrome c oxidase","type":"narrow"},{"name":"inhibition of complex IV (mitochondrial electron transport) activity","type":"related"},{"name":"inhibition of cytochrome a3 activity","type":"narrow"},{"name":"inhibition of cytochrome aa3 activity","type":"narrow"},{"name":"inhibition of cytochrome c oxidase activity","type":"narrow"},{"name":"inhibition of cytochrome oxidase activity","type":"related"},{"name":"inhibition of cytochrome-c oxidase activity","type":"narrow"},{"name":"inhibition of ferrocytochrome c oxidase","type":"narrow"},{"name":"inhibition of ferrocytochrome-c:oxygen oxidoreductase","type":"narrow"},{"name":"inhibition of indophenol oxidase","type":"narrow"},{"name":"inhibition of indophenolase","type":"narrow"},{"name":"inhibition of warburg's respiratory enzyme activity","type":"related"},{"name":"negative regulation of NADH cytochrome c oxidase","type":"exact"},{"name":"negative regulation of aa3-type cytochrome c oxidase","type":"narrow"},{"name":"negative regulation of ba3-type cytochrome c oxidase","type":"narrow"},{"name":"negative regulation of caa3-type cytochrome c oxidase","type":"narrow"},{"name":"negative regulation of cbb3-type cytochrome c oxidase","type":"narrow"},{"name":"negative regulation of complex IV (mitochondrial electron transport) activity","type":"related"},{"name":"negative regulation of cytochrome a3 activity","type":"narrow"},{"name":"negative regulation of cytochrome aa3 activity","type":"narrow"},{"name":"negative regulation of cytochrome c oxidase activity","type":"exact"},{"name":"negative regulation of cytochrome oxidase activity","type":"related"},{"name":"negative regulation of ferrocytochrome c oxidase","type":"narrow"},{"name":"negative regulation of ferrocytochrome-c:oxygen oxidoreductase","type":"narrow"},{"name":"negative regulation of indophenol oxidase","type":"narrow"},{"name":"negative regulation of indophenolase","type":"narrow"},{"name":"negative regulation of warburg's respiratory enzyme activity","type":"related"}],"termid":"GO:1905376"}


id: GO:0018754
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.","definition_xrefs":["PMID:1991731"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines","termid":"GO:0016813"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016787","GO:0016810","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"ammelide aminohydrolase activity","secondary_identifiers":["MetaCyc:RXN-8017"],"termid":"GO:0018754"}


id: PBO:0001057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"curved DNA-binding protein Cdb4, peptidase family","termid":"PBO:0001057"}


id: MONDO:0018087
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A viral infectious disease caused by RNA viruses in the Arenaviridae, Bunyaviridae, Filoviridae, or Flaviviridae family, and characterized by a severe multisystem syndrome, with damage to the vascular system and hemorrhaging.","direct_ancestors":[{"relation_name":"is_a","term_name":"viral infectious disease","termid":"MONDO:0005108"},{"relation_name":"is_a","term_name":"hemorrhagic fever","termid":"MONDO:0600002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"viral hemorrhagic fever","secondary_identifiers":["NCIT:C36170","UMLS:C0019104","GARD:5494","MESH:D006482","Orphanet:341","MEDGEN:9213","SCTID:240523007"],"synonyms":[{"name":"VHF","type":"exact"},{"name":"VHFs","type":"exact"},{"name":"haemorrhagic fever","type":"broad"},{"name":"haemorrhagic fevers, viral","type":"exact"},{"name":"hemorrhagic fever","type":"broad"},{"name":"hemorrhagic fevers","type":"broad"},{"name":"viral haemorrhagic fever","type":"exact"}],"termid":"MONDO:0018087","xrefs":{"Monarch":{"xref_id":"0018087"}}}


id: PBO:0026657
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-heterochromatin_assembly_beyond_boundary_element_IRC1L","termid":"PBO:0026657"}


id: PBO:0002711
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aspartyl aminopeptidase Aap1","termid":"PBO:0002711"}


id: MOD:00727
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a mannose group through a glycosidic bond,","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycosylated residue","termid":"MOD:00693"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"mannosylated","synonyms":[{"name":"Man","type":"exact"}],"termid":"MOD:00727"}


id: FYPO:0007074
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mycophenolic acid.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0002057","FYPO:0002060","FYPO:0000139","FYPO:0000003","FYPO:0002058"],"is_obsolete":false,"name":"normal growth on mycophenolic acid","synonyms":[{"name":"normal cell population growth in presence of mycophenolic acid","type":"exact"},{"name":"normal cell population growth on MPA","type":"exact"},{"name":"normal cell population growth on mycophenolic acid","type":"exact"},{"name":"normal vegetative cell population growth on mycophenolic acid","type":"exact"}],"termid":"FYPO:0007074"}


id: GO:0004968
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor activity","termid":"GO:0004930"},{"relation_name":"is_a","term_name":"protein-hormone receptor activity","termid":"GO:0016500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"gonadotropin-releasing hormone receptor activity","synonyms":[{"name":"GnRH receptor activity","type":"exact"},{"name":"gonadotrophin-releasing hormone receptor activity","type":"exact"}],"termid":"GO:0004968"}


id: GO:0070071
data:
  {"annotated_genes":["SJAG_05306","SJAG_01939","SJAG_04899","SJAG_04450","SJAG_06135","SJAG_01503","SJAG_00301","SJAG_01838","SJAG_04454","SJAG_06514","SJAG_07008","SJAG_00771"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73850,78451,74491,110030,110451,89386],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033615"},{"annotations":[64294,102300,110470,116848,64093,67613],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070072"}]},"cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00301":null,"SJAG_00771":null,"SJAG_01503":null,"SJAG_01838":null,"SJAG_01939":null,"SJAG_04450":null,"SJAG_04454":null,"SJAG_04899":null,"SJAG_05306":null,"SJAG_06135":null,"SJAG_06514":null,"SJAG_07008":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0065003"],"is_obsolete":false,"name":"proton-transporting two-sector ATPase complex assembly","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0070071","terms_by_termid":{"GO:0033615":null,"GO:0070072":null}}


id: GO:0003029
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.","definition_xrefs":["GOC:mtg_cardio"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of hypoxic conditions in blood by chemoreceptor signaling","termid":"GO:0002007"},{"relation_name":"part_of","term_name":"regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling","termid":"GO:0003027"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of hypoxic conditions in blood by carotid body chemoreceptor signaling","synonyms":[{"name":"detection of hypoxic conditions in blood by carotid body chemoreceptor signalling","type":"exact"}],"termid":"GO:0003029"}


id: PBO:0078518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRIM8 divergent transcript","termid":"PBO:0078518"}


id: FYPO:0006111
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in subtelomeric regions does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished histone H3-K9 dimethylation during vegetative growth","termid":"FYPO:0007886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0005447","FYPO:0001320","FYPO:0002494","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"abolished histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth","synonyms":[{"name":"abolished histone H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth","type":"exact"},{"name":"abolished histone H3-K9 dimethylation at subtelomere during vegetative growth","type":"exact"},{"name":"abolished histone H3-K9 dimethylation at subtelomeric heterochromatin during mitotic cell cycle","type":"related"},{"name":"abolished histone H3-K9 dimethylation at subtelomeric region during vegetative growth","type":"exact"},{"name":"abolished histone H3K9me2 at subtelomeric heterochromatin during vegetative growth","type":"exact"},{"name":"abolished histone lysine H3 K9 dimethylation at subtelomeric heterochromatin during vegetative growth","type":"exact"},{"name":"abolished subtelomeric histone H3-K9 dimethylation during vegetative growth","type":"exact"},{"name":"histone H3-K9 dimethylation abolished at subtelomeric heterochromatin during vegetative growth","type":"exact"},{"name":"histone H3-K9 dimethylation absent at subtelomeric heterochromatin during vegetative growth","type":"exact"}],"termid":"FYPO:0006111"}


id: MONDO:0001527
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"strabismus","termid":"MONDO:0003432"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conjugate gaze palsy","secondary_identifiers":["DOID:12445","MEDGEN:675273","UMLS:C0702143","ICD9:378.81","SCTID:1534008"],"synonyms":[{"name":"palsy of conjugate gaze","type":"exact"}],"termid":"MONDO:0001527","xrefs":{"Monarch":{"xref_id":"0001527"}}}


id: MONDO:0006910
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete pituitary-dependent Cushing disease (obsolete MONDO:0006910)","termid":"MONDO:0006910","xrefs":{"Monarch":{"xref_id":"0006910"}}}


id: PBO:0057132
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 216a","termid":"PBO:0057132"}


id: PBO:0070064
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6atac small nuclear 21, pseudogene","termid":"PBO:0070064"}


id: GO:1905203
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of connective tissue replacement.","definition_xrefs":["GOC:BHF","PMID:25590961","GO_REF:0000058","GOC:bc","GOC:BHF_miRNA","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of tissue remodeling","termid":"GO:0034103"},{"relation_name":"regulates","term_name":"connective tissue replacement","termid":"GO:0097709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of connective tissue replacement","termid":"GO:1905203"}


id: MONDO:0002043
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The turning outward (eversion) of the edge of the eyelid, resulting in the exposure of the palpebral conjunctiva. (Dorland, 27th ed)","definition_xrefs":["MESH:D004483"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eyelid disorder","termid":"MONDO:0003382"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"ectropion","secondary_identifiers":["MEDGEN:4448","ICD9:374.1","SCTID:62909004","HP:0000656","ICD9:374.10","DOID:1570","UMLS:C0013592"],"synonyms":[{"name":"ectropion","type":"exact"},{"name":"ectropion (disease)","type":"exact"},{"name":"ectropion of eyelid","type":"exact"},{"name":"everted margin","type":"exact"}],"termid":"MONDO:0002043","xrefs":{"Monarch":{"xref_id":"0002043"}}}


id: GO:0032230
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synaptic transmission, GABAergic","termid":"GO:0032228"},{"relation_name":"is_a","term_name":"positive regulation of synaptic transmission","termid":"GO:0050806"},{"relation_name":"positively_regulates","term_name":"synaptic transmission, GABAergic","termid":"GO:0051932"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of synaptic transmission, GABAergic","synonyms":[{"name":"activation of synaptic transmission, GABAergic","type":"narrow"},{"name":"stimulation of synaptic transmission, GABAergic","type":"narrow"},{"name":"up regulation of synaptic transmission, GABAergic","type":"exact"},{"name":"up-regulation of synaptic transmission, GABAergic","type":"exact"},{"name":"upregulation of synaptic transmission, GABAergic","type":"exact"}],"termid":"GO:0032230"}


id: GO:0140874
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture.","definition_xrefs":["PMID:27602587"],"direct_ancestors":[{"relation_name":"is_a","term_name":"terpenoid biosynthetic process","termid":"GO:0016114"},{"relation_name":"is_a","term_name":"ketone biosynthetic process","termid":"GO:0042181"},{"relation_name":"is_a","term_name":"lactone biosynthetic process","termid":"GO:1901336"},{"relation_name":"is_a","term_name":"tertiary alcohol biosynthetic process","termid":"GO:1902645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"paraherquonin biosynthetic process","synonyms":[{"name":"paraherquonin anabolism","type":"exact"},{"name":"paraherquonin biosynthesis","type":"exact"},{"name":"paraherquonin formation","type":"exact"},{"name":"paraherquonin synthesis","type":"exact"}],"termid":"GO:0140874"}


id: MONDO:0005383
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An anxiety disorder characterized by multiple unexpected panic attacks with persistent concern of recurring attacks. Panic disorder may or may not be accompanied by agoraphobia.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anxiety disorder","termid":"MONDO:0005618"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"panic disorder","secondary_identifiers":["MEDGEN:14588","NCIT:C34890","SCTID:371631005","UMLS:C0030319","ICD9:300.01","icd11.foundation:56162827","MESH:D016584","DOID:594","EFO:0004262"],"synonyms":[{"name":"panic anxiety syndrome","type":"exact"}],"termid":"MONDO:0005383","xrefs":{"Monarch":{"xref_id":"0005383"}}}


id: PBO:0068067
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 372","termid":"PBO:0068067"}


id: MONDO:0006985
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete subependymoma (obsolete MONDO:0006985)","termid":"MONDO:0006985","xrefs":{"Monarch":{"xref_id":"0006985"}}}


id: MONDO:1010287
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pulmonary hypertension that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiovascular disorder, non-human animal","termid":"MONDO:1011306"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pulmonary hypertension, non-human animal","secondary_identifiers":["OMIA:000841"],"termid":"MONDO:1010287","xrefs":{"Monarch":{"xref_id":"1010287"}}}


id: PBO:0003706
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally regulates MBF target genes","termid":"PBO:0003706"}


id: PR:O59760
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC1020.07 gene.","definition_xrefs":["UniProtKB:O59760","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized hydrolase C1020.07 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1020.07","synonyms":[{"name":"Spom972h-SPCC1020.07","type":"exact"}],"termid":"PR:O59760"}


id: GO:0045300
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 H+ + O2 + octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] = (9Z)-octadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin].","definition_xrefs":["RHEA:11776"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water","termid":"GO:0016717"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"stearoyl-[ACP] desaturase activity","secondary_identifiers":["EC:1.14.19.2","KEGG_REACTION:R03370","MetaCyc:RXN-7903"],"synonyms":[{"name":"acyl-[acyl-carrier-protein] desaturase activity","type":"related"},{"name":"acyl-acyl-carrier-protein desaturase activity","type":"related"},{"name":"acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity","type":"related"},{"name":"stearyl acyl carrier protein desaturase activity","type":"related"},{"name":"stearyl-ACP desaturase activity","type":"related"}],"termid":"GO:0045300"}


id: PBO:0048398
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"growth arrest specific 5","termid":"PBO:0048398"}


id: PBO:0109258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 120 member A opposite strand","termid":"PBO:0109258"}


id: GO:0032590
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The portion of the plasma membrane surrounding a dendrite.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron projection membrane","termid":"GO:0032589"},{"relation_name":"part_of","term_name":"dendrite","termid":"GO:0030425"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"dendrite membrane","termid":"GO:0032590"}


id: GO:0060255
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id: FYPO:0007027
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  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex is abolished, and the protein is present in the cytoplasm instead.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization to medial cortex during vegetative growth","termid":"FYPO:0002555"},{"relation_name":"is_a","term_name":"abolished protein localization to cell cortex, with protein mislocalized to cytoplasm, during vegetative growth","termid":"FYPO:0005501"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0000138","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to medial cortex, with protein mislocalized to cytoplasm, during vegetative growth","synonyms":[{"name":"abolished protein localisation to medial cortex, with protein mislocalised to cytoplasm, during vegetative growth","type":"exact"},{"name":"abolished protein localization to medial cortex, with protein mislocalized to cytoplasm during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to medial ring, with protein mislocalized to cytoplasm, during vegetative growth","type":"exact"},{"name":"protein localization to medial cortex abolished, with protein mislocalized to cytoplasm, during vegetative growth","type":"exact"}],"termid":"FYPO:0007027"}


id: GO:1900322
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport.","definition_xrefs":["GOC:TermGenie","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of transport","termid":"GO:0051051"},{"relation_name":"is_a","term_name":"regulation of maltotetraose transport","termid":"GO:1900321"},{"relation_name":"negatively_regulates","term_name":"maltotetraose transport","termid":"GO:2001099"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of maltotetraose transport","synonyms":[{"name":"down regulation of maltotetraose transport","type":"exact"},{"name":"down-regulation of maltotetraose transport","type":"exact"},{"name":"downregulation of maltotetraose transport","type":"exact"},{"name":"inhibition of maltotetraose transport","type":"narrow"}],"termid":"GO:1900322"}


id: GO:0048327
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesodermal cell fate specification","termid":"GO:0007501"},{"relation_name":"part_of","term_name":"axial mesodermal cell fate commitment","termid":"GO:0048322"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"axial mesodermal cell fate specification","synonyms":[{"name":"axial mesoderm cell fate specification","type":"exact"}],"termid":"GO:0048327"}


id: GO:0051608
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nitrogen compound transport","termid":"GO:0071705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"histamine transport","termid":"GO:0051608"}


id: MONDO:0018637
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare autosomal recessive disease characterized by the buildup in the blood of fat particles called chylomicrons (chylomicronemia), severe hypertriglyceridemia, and the risk of recurrent and potentially fatal pancreatitis and other complications. It is caused by mutations in the gene encoding LPL or, less frequently, by mutations in genes encoding other proteins necessary for LPL function.","definition_xrefs":["PMID:25470695","PMID:22239554"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"familial chylomicronemia syndrome","secondary_identifiers":["MEDGEN:1778100","DOID:0111417","GARD:6414","Orphanet:444490","UMLS:C5442313"],"termid":"MONDO:0018637","xrefs":{"Monarch":{"xref_id":"0018637"}}}


id: MONDO:0016085
data:
  {"annotated_genes":["SJAG_02349","SJAG_00288"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87055],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007204"},{"annotations":[85796],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014573"}]},"cv_name":"mondo","definition":"An extremely rare form of bone dysplasia characterized by the features of osteogenesis imperfecta such as bone fragility associated with multiple fractures, bone deformities (metaphyseal irregularities and bowing of the long bones) and blue sclera, in association with growth failure, craniosynostosis, hydrocephalus, ocular proptosis, and distinctive facial features (e.g. frontal bossing, midface hypoplasia, and micrognathia).","definition_xrefs":["Orphanet:2050"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"osteogenesis imperfecta","termid":"MONDO:0019019"},{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with decreased bone density (obsolete MONDO:0019704)","termid":"MONDO:0019704"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00288":null,"SJAG_02349":null},"genotype_count":0,"is_obsolete":false,"name":"Cole-Carpenter syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1862178","NCIT:C130985","OMIMPS:112240","icd11.foundation:1458793358","MEDGEN:350614","MESH:C535963","DOID:0060438","GARD:1425"],"synonyms":[{"name":"Cole Carpenter syndrome","type":"related"},{"name":"bone fragility-craniosynostosis-proptosis-hydrocephalus syndrome","type":"exact"}],"termid":"MONDO:0016085","terms_by_termid":{"MONDO:0007204":null,"MONDO:0014573":null},"xrefs":{"Monarch":{"xref_id":"0016085"}}}


id: GO:0141159
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont inhibits or disrupts the normal acidification of host phagosomes. Mechanisms by which a symbiont prevents host phagosome acidification include the inhibitition of host V-ATPase, the proton pump that acidifies the phagosome, or disruption of the phagosome membrane by pore-forming toxin. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:33505976","PMID:20333253","PMID:22087003"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host defense response","termid":"GO:0052031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host phagosome acidification","termid":"GO:0141159"}


id: PBO:0034615
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-globally_decreased_meiotic_recombination","termid":"PBO:0034615"}


id: GO:0052470
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by host of symbiont signal transduction pathway (obsolete GO:0052470)","termid":"GO:0052470"}


id: PBO:0076534
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taste 2 receptor member 60","termid":"PBO:0076534"}


id: GO:1901104
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving tetracenomycin C.","definition_xrefs":["GOC:TermGenie","GOC:yaf","UniPathway:UPA00174"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyketide metabolic process","termid":"GO:0030638"},{"relation_name":"is_a","term_name":"ketone metabolic process","termid":"GO:0042180"},{"relation_name":"is_a","term_name":"tertiary alcohol metabolic process","termid":"GO:1902644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0019748"],"is_obsolete":false,"name":"tetracenomycin C metabolic process","synonyms":[{"name":"tetracenomycin C metabolism","type":"exact"}],"termid":"GO:1901104"}


id: PBO:0027714
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_after_spore_germination,_single_cell_division,_small_cell","termid":"PBO:0027714"}


id: PBO:0054447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1844","termid":"PBO:0054447"}


id: PBO:0064757
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase B","termid":"PBO:0064757"}


id: PBO:0114426
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAJC6 antisense RNA 1","termid":"PBO:0114426"}


id: PBO:0081616
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 544","termid":"PBO:0081616"}


id: PATO:0001406
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei.","definition_xrefs":["Biology-online:Biology-online"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multinucleate","termid":"PATO:0001908"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"binucleate","termid":"PATO:0001406"}


id: MONDO:1011159
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Osteoarthritis that occurs in koala.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteoarthritis, non-human animal","termid":"MONDO:1010297"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteoarthritis, koala","secondary_identifiers":["OMIA:000747-38626"],"termid":"MONDO:1011159","xrefs":{"Monarch":{"xref_id":"1011159"}}}


id: GO:0045711
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.","definition_xrefs":["GOC:go_curators","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of salivary gland boundary specification","termid":"GO:0045706"},{"relation_name":"is_a","term_name":"regulation of adult salivary gland boundary specification","termid":"GO:0045707"},{"relation_name":"positively_regulates","term_name":"adult salivary gland boundary specification","termid":"GO:0007434"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of adult salivary gland boundary specification","synonyms":[{"name":"activation of adult salivary gland determination","type":"narrow"},{"name":"positive regulation of adult salivary gland determination","type":"exact"},{"name":"stimulation of adult salivary gland determination","type":"narrow"},{"name":"up regulation of adult salivary gland determination","type":"exact"},{"name":"up-regulation of adult salivary gland determination","type":"exact"},{"name":"upregulation of adult salivary gland determination","type":"exact"}],"termid":"GO:0045711"}


id: PBO:0116625
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARF GTPase 2, pseudogene","termid":"PBO:0116625"}


id: GO:0036376
data:
  {"annotated_genes":["SJAG_01541"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[67227],"is_not":false,"summary":null,"term":"GO:0036376"}]},"cv_name":"biological_process","definition":"The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.","definition_xrefs":["GOC:vw","PMID:14674689"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium ion transmembrane transport","termid":"GO:0035725"},{"relation_name":"is_a","term_name":"export across plasma membrane","termid":"GO:0140115"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01541":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179","GO:0055085"],"is_obsolete":false,"name":"sodium ion export across plasma membrane","references_by_uniquename":{"GO_REF:0000002":null},"secondary_identifiers":["GO:0098667","GO:0071436"],"synonyms":[{"name":"sodium export","type":"related"},{"name":"sodium ion export","type":"related"},{"name":"sodium ion export from cell","type":"exact"}],"termid":"GO:0036376","terms_by_termid":{"GO:0036376":null}}


id: GO:0070310
data:
  {"annotated_genes":["SJAG_00429","SJAG_00364"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[101176,106923],"is_not":false,"summary":null,"term":"GO:0070310"}]},"cv_name":"cellular_component","definition":"A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.","definition_xrefs":["PMID:14724280","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00364":null,"SJAG_00429":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"ATR-ATRIP complex","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"Mec1-Lcd1 complex","type":"narrow"},{"name":"Rad3-Rad26 complex","type":"narrow"}],"termid":"GO:0070310","terms_by_termid":{"GO:0070310":null}}


id: MONDO:0013864
data:
  {"annotated_genes":["SJAG_01067"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86497],"is_not":false,"summary":null,"term":"MONDO:0013864"}]},"cv_name":"mondo","definition":"Any Cornelia de Lange syndrome in which the cause of the disease is a mutation in the RAD21 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Cornelia de Lange syndrome","termid":"MONDO:0016033"},{"relation_name":"is_a","term_name":"non-syndromic limb reduction defect","termid":"MONDO:0019713"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01067":null},"genotype_count":0,"is_obsolete":false,"name":"Cornelia de Lange syndrome 4","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0080508","UMLS:C3553517","OMIM:614701","MEDGEN:766431","GARD:15837"],"synonyms":[{"name":"CDLS4","type":"related"},{"name":"Cornelia DE Lange syndrome 4","type":"related"},{"name":"Cornelia De Lange syndrome type 4","type":"exact"},{"name":"Cornelia de Lange syndrome 4","type":"exact"},{"name":"Cornelia de Lange syndrome caused by mutation in RAD21","type":"exact"},{"name":"RAD21 Cornelia de Lange syndrome","type":"exact"}],"termid":"MONDO:0013864","terms_by_termid":{"MONDO:0013864":null},"xrefs":{"Monarch":{"xref_id":"0013864"}}}


id: GO:0070436
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.","definition_xrefs":["PMID:7798267","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0005575","GO:0032991"],"is_obsolete":false,"name":"Grb2-EGFR complex","synonyms":[{"name":"Grb2-Egfr complex, EGF stimulated","type":"narrow"}],"termid":"GO:0070436"}


id: FYPO:0003009
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere outer repeat regions of a chromosome is increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to centromere during vegetative growth","termid":"FYPO:0000449"},{"relation_name":"is_a","term_name":"increased protein localization to chromosome during vegetative growth","termid":"FYPO:0002840"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"increased protein localization to centromere outer repeat","synonyms":[{"name":"increased protein localisation to centromere outer repeat","type":"exact"},{"name":"increased protein localisation to centromeric outer repeat region","type":"exact"},{"name":"increased protein localization to centromere outer repeat during mitotic cell cycle","type":"related"},{"name":"increased protein localization to centromere outer repeat during vegetative growth","type":"exact"},{"name":"increased protein localization to chromosome, centric outer repeat region","type":"exact"},{"name":"increased protein localization to chromosome, centromeric outer repeat region","type":"exact"},{"name":"increased protein localization to pericentric region","type":"related"},{"name":"increased protein localization to pericentromeric region","type":"related"}],"termid":"FYPO:0003009"}


id: FYECO:0000132
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Any experimental condition pertaining to the external environment in which an experiment is conducted.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fission yeast phenotype condition","termid":"FYECO:0000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"grouping experimental environment","termid":"FYECO:0000132"}


id: MONDO:0007192
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beta-amino acids, renal transport of","secondary_identifiers":["UMLS:C1862289","MEDGEN:349470","OMIM:109660"],"synonyms":[{"name":"AABT","type":"exact"},{"name":"BETA-amino acids, renal TRANSPORT OF","type":"related"},{"name":"taurine renal reabsorption","type":"related"}],"termid":"MONDO:0007192","xrefs":{"Monarch":{"xref_id":"0007192"}}}


id: FYPO:0006225
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tetramethylammonium. Cells stop growing (and may die) at a concentration of tetramethylammonium that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002683","FYPO:0005447","FYPO:0000003","FYPO:0001985","FYPO:0000139"],"is_obsolete":false,"name":"sensitive to tetramethylammonium","synonyms":[{"name":"hypersensitive to tetramethylammonium","type":"exact"},{"name":"sensitive to TMA","type":"exact"},{"name":"sensitive to tetramethylammonium during mitotic cell cycle","type":"related"},{"name":"sensitive to tetramethylammonium during vegetative growth","type":"exact"}],"termid":"FYPO:0006225"}


id: MONDO:0003796
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A Kaposi sarcoma arising from the rectum.","definition_xrefs":["NCIT:C5550"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rectum sarcoma","termid":"MONDO:0002168"},{"relation_name":"is_a","term_name":"colorectal Kaposi sarcoma","termid":"MONDO:0024659"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"rectum Kaposi sarcoma","secondary_identifiers":["DOID:6190","UMLS:C1335681","MEDGEN:277575"],"synonyms":[{"name":"Kaposi's sarcoma (disease) of rectum","type":"exact"},{"name":"Kaposi's sarcoma of rectum","type":"exact"},{"name":"Kaposi's sarcoma of the rectum","type":"exact"},{"name":"rectal Kaposi sarcoma","type":"exact"},{"name":"rectal Kaposi's sarcoma","type":"exact"},{"name":"rectum Kaposi sarcoma","type":"exact"},{"name":"rectum Kaposi's sarcoma","type":"related"},{"name":"rectum Kaposi's sarcoma (disease)","type":"exact"}],"termid":"MONDO:0003796","xrefs":{"Monarch":{"xref_id":"0003796"}}}


id: GO:0034652
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging.","definition_xrefs":["GOC:jp","PMID:18660802","GOC:tb","GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete extrachromosomal circular DNA localization involved in cell aging (obsolete GO:0034652)","synonyms":[{"name":"extrachromosomal circular DNA localisation involved in cell aging","type":"exact"},{"name":"extrachromosomal circular DNA localization during cell ageing","type":"exact"},{"name":"extrachromosomal circular DNA localization during cell aging","type":"related"}],"termid":"GO:0034652"}


id: FYPO:0002770
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the spindle pole body is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to spindle pole body","termid":"FYPO:0002769"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000138","FYPO:0000002"],"is_obsolete":false,"name":"decreased protein localization to spindle pole body","synonyms":[{"name":"decreased protein localisation to spindle pole body","type":"exact"},{"name":"decreased protein localization to SPB","type":"exact"},{"name":"reduced protein localization to spindle pole body","type":"exact"}],"termid":"FYPO:0002770"}


id: GO:0010890
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.","definition_xrefs":["GOC:dph","GOC:BHF","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of lipid storage","termid":"GO:0010884"},{"relation_name":"is_a","term_name":"regulation of triglyceride storage","termid":"GO:0010889"},{"relation_name":"positively_regulates","term_name":"triglyceride storage","termid":"GO:0030730"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of triglyceride storage","synonyms":[{"name":"positive regulation of sequestering of triacylglycerol","type":"exact"},{"name":"positive regulation of sequestering of triglyceride","type":"exact"},{"name":"positive regulation of triglyceride sequestration","type":"exact"}],"termid":"GO:0010890"}


id: MONDO:1011819
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cancer or benign tumor, non-human animal","termid":"MONDO:1011305"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic myelogenous leukemia, non-human animal","secondary_identifiers":["OMIA:001513"],"termid":"MONDO:1011819","xrefs":{"Monarch":{"xref_id":"1011819"}}}


id: PBO:0076492
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell-interacting, activating receptor on myeloid cells 1","termid":"PBO:0076492"}


id: GO:0036133
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.","definition_xrefs":["PMID:3461463","PMID:8200461","PMID:3823488","GOC:mw","KEGG_REACTION:R05060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"11-hydroxythromboxane B2 dehydrogenase activity","secondary_identifiers":["Reactome:R-HSA-2161732","RHEA:52312"],"synonyms":[{"name":"NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity","type":"exact"}],"termid":"GO:0036133"}


id: MONDO:0015696
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Good syndrome, also known as thymoma-immunodeficiency, is a very rare acquired immunodeficiency syndrome characterized by the association of thymoma and combined B-cell and T-cell immunodeficiency of adult onset with increased susceptibility to infections.","definition_xrefs":["Orphanet:169105"],"direct_ancestors":[{"relation_name":"is_a","term_name":"agammaglobulinemia","termid":"MONDO:0015977"},{"relation_name":"is_a","term_name":"acquired immunodeficiency","termid":"MONDO:0017769"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"Good syndrome","secondary_identifiers":["icd11.foundation:812332735","SCTID:9893005","UMLS:C0221027","GARD:8622","DOID:0060028","MEDGEN:67437"],"synonyms":[{"name":"immunodeficiency with thymoma","type":"related"},{"name":"thymoma with hypogammaglobulinemia","type":"exact"},{"name":"thymoma-immunodeficiency","type":"exact"},{"name":"thymoma-immunodeficiency syndrome","type":"exact"}],"termid":"MONDO:0015696","xrefs":{"Monarch":{"xref_id":"0015696"}}}


id: GO:2000404
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of T cell migration.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lymphocyte migration","termid":"GO:2000401"},{"relation_name":"regulates","term_name":"T cell migration","termid":"GO:0072678"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of T cell migration","synonyms":[{"name":"regulation of T lymphocyte migration","type":"exact"},{"name":"regulation of T-cell migration","type":"exact"},{"name":"regulation of T-lymphocyte migration","type":"exact"}],"termid":"GO:2000404"}


id: PBO:0087960
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transmembrane protein with a highly basic C-terminal region","termid":"PBO:0087960"}


id: PBO:0070398
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAR related orphan receptor C","termid":"PBO:0070398"}


id: PBO:0029536
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_microcolony,_small_cells_(obsolete_FYPO:0002186)","termid":"PBO:0029536"}


id: MONDO:0017305
data:
  {"annotated_genes":["SJAG_03011","SJAG_00938","SJAG_00108","SJAG_02453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87378,87377],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008962"},{"annotations":[86473],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014885"},{"annotations":[86333],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011997"}]},"cv_name":"mondo","definition":"A oculocutaneous albinism that is part of a larger syndrome.","definition_xrefs":["MONDO:patterns/syndromic"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"disorder of melanin metabolism","termid":"MONDO:0018134"},{"relation_name":"is_a","term_name":"hypopigmentation of the skin","termid":"MONDO:0019290"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00108":null,"SJAG_00938":null,"SJAG_02453":null,"SJAG_03011":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0005093"],"is_obsolete":false,"name":"syndromic oculocutaneous albinism","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1843078","Orphanet:284811","ICD10CM:E70.3","UMLS:C5681016","GARD:21125"],"synonyms":[{"name":"syndrome associated with oculocutaneous albinism","type":"exact"},{"name":"syndromic oculocutaneous albinism","type":"exact"}],"termid":"MONDO:0017305","terms_by_termid":{"MONDO:0008962":null,"MONDO:0011997":null,"MONDO:0014885":null},"xrefs":{"Monarch":{"xref_id":"0017305"}}}


id: PBO:0051465
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable (I)-20 (pseudogene)","termid":"PBO:0051465"}


id: SOFP:symbol
data:
  {"annotation_feature_type":"gene","cv_name":"feature_property","definition":"Community symbol","direct_ancestors":[{"relation_name":"is_a","term_name":"feature_property","termid":"SOFP:feature_property"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"symbol","termid":"SOFP:symbol"}


id: GO:0045544
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2 2-oxoglutarate + gibberellin A12 (GA12) + H+ + 3 O2 = 3 CO2 + gibberellin A9 (GA9) + 2 H2O + 2 succinate. This reaction results in the oxidation of C-20 gibberellins to form the corresponding C-19 lactones, via a three-step oxidation at C-20 of the GA skeleton. Also converts GA53 to GA20. GA25 is also formed as a minor product.","definition_xrefs":["PMID:32652020","PMID:7604047"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2-oxoglutarate-dependent dioxygenase activity","termid":"GO:0016706"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"gibberellin 20-oxidase activity","termid":"GO:0045544"}


id: GO:0007030
data:
  {"annotated_genes":["SJAG_01003","SJAG_00357","SJAG_04598","SJAG_01516","SJAG_01571","SJAG_01633","SJAG_03670","SJAG_04023","SJAG_02120","SJAG_04528","SJAG_00284","SJAG_01459","SJAG_00578","SJAG_00557","SJAG_04196","SJAG_03270","SJAG_01467"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72521,72679,74389,74813,75680,76805,77274,77969,78564,79073,102498,109804,119106],"is_not":false,"summary":null,"term":"GO:0007030"},{"annotations":[57752,74246,76518,78120],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048280"}]},"cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.","definition_xrefs":["GOC:jl","GOC:dph","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle organization","termid":"GO:0006996"},{"relation_name":"part_of","term_name":"endomembrane system organization","termid":"GO:0010256"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00284":null,"SJAG_00357":null,"SJAG_00557":null,"SJAG_00578":null,"SJAG_01003":null,"SJAG_01459":null,"SJAG_01467":null,"SJAG_01516":null,"SJAG_01571":null,"SJAG_01633":null,"SJAG_02120":null,"SJAG_03270":null,"SJAG_03670":null,"SJAG_04023":null,"SJAG_04196":null,"SJAG_04528":null,"SJAG_04598":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"Golgi organization","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"Golgi apparatus organization","type":"exact"},{"name":"Golgi organisation","type":"exact"},{"name":"Golgi organization and biogenesis","type":"related"}],"termid":"GO:0007030","terms_by_termid":{"GO:0007030":null,"GO:0048280":null}}


id: GO:0048831
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of shoot development.","definition_xrefs":["GOC:tb","PMID:16361392"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of developmental process","termid":"GO:0050793"},{"relation_name":"regulates","term_name":"shoot system development","termid":"GO:0048367"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of shoot system development","synonyms":[{"name":"regulation of shoot development","type":"exact"}],"termid":"GO:0048831"}


id: MOD:01859
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively crosslinks an L-cysteine residue and an L-phenylalanine residue to form 4-amino-3-isothiazolidinone-L-phenylalanine.","definition_xrefs":["PubMed:17502599","RESID:AA0562"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isothiazolidinone ring crosslinked residues","termid":"MOD:01861"},{"relation_name":"is_a","term_name":"crosslinked L-cysteine residue","termid":"MOD:02044"},{"relation_name":"is_a","term_name":"crosslinked L-phenylalanine residue","termid":"MOD:02053"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"4-amino-3-isothiazolidinone-L-phenylalanine","synonyms":[{"name":"(2S)-2-[(4R)-4-amino-3-oxo-1,2-thiazolidin-2-yl]-3-phenylpropanoic acid","type":"exact"},{"name":"2-(4-amino-3-oxo-isothiazolidin-2-yl)-3-phenylpropanoic acid","type":"exact"},{"name":"4-amino-3-isothiazolidinone-L-phenylalanine","type":"exact"},{"name":"CROSSLNK N,N-(cysteine-1,S-diyl)phenylalanine (Cys-Phe)","type":"exact"},{"name":"N,N-(L-cysteine-1,S-diyl)-L-phenylalanine","type":"exact"},{"name":"cysteinyl phenylalanine sulfenamide","type":"exact"},{"name":"phenylalanine-cysteine sulfenyl amide cross-link","type":"exact"},{"name":"phenylalanine-cysteine sulphenyl amide cross-link","type":"exact"}],"termid":"MOD:01859"}


id: SO:0001645
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A measurable sequence feature that varies within a population.","definition_xrefs":["SO:db"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological_region","termid":"SO:0001411"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"genetic_marker","synonyms":[{"name":"genetic marker","type":"related"}],"termid":"SO:0001645"}


id: FYPO:0005835
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transport phenotype observed in the vegetative growth phase of the life cycle in which the transport of proteins along microtubules does not occur. Transport of all proteins or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein transport along microtubule during vegetative growth","termid":"FYPO:0005830"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"abolished protein transport along microtubule during vegetative growth","synonyms":[{"name":"abolished protein movement along microtubule during vegetative growth","type":"exact"},{"name":"abolished protein transport along microtubule during mitotic cell cycle","type":"related"},{"name":"protein transport along microtubule abolished during vegetative growth","type":"exact"}],"termid":"FYPO:0005835"}


id: GO:0034549
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid.","definition_xrefs":["UM-BBD_reactionID:r0827"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines","termid":"GO:0016814"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016810"],"is_obsolete":false,"name":"N-cyclopropylammelide alkylamino hydrolase activity","secondary_identifiers":["KEGG_REACTION:R06972","MetaCyc:RXN-8020"],"termid":"GO:0034549"}


id: GO:0043663
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell.","definition_xrefs":["GOC:cc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host symbiosome","termid":"GO:0043658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host bacteroid-containing symbiosome","termid":"GO:0043663"}


id: GO:0019407
data:
  {"annotated_genes":["SJAG_00237"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[73020],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006062"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hexitol metabolic process","termid":"GO:0006059"},{"relation_name":"is_a","term_name":"alditol catabolic process","termid":"GO:0019405"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00237":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0005975"],"is_obsolete":false,"name":"hexitol catabolic process","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"hexitol breakdown","type":"exact"},{"name":"hexitol catabolism","type":"exact"},{"name":"hexitol degradation","type":"exact"}],"termid":"GO:0019407","terms_by_termid":{"GO:0006062":null}}


id: MONDO:0015832
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"True unicornuate uterus is a rare, non-syndromic uterovaginal malformation characterized by a crescent-shaped, small-sized uterus containing a single horn and fallopian tube with no rudimentary horn. Urinary tract anomalies are frequently associated.","definition_xrefs":["Orphanet:180074"],"direct_ancestors":[{"relation_name":"is_a","term_name":"unilateral aplasia of the mullerian ducts","termid":"MONDO:0015831"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"true unicornuate uterus","secondary_identifiers":["GARD:20174","icd11.foundation:113532659","UMLS:C5848180","MEDGEN:1863468"],"synonyms":[{"name":"complete unilateral Mullerian aplasia","type":"exact"},{"name":"complete unilateral Müllerian aplasia","type":"exact"},{"name":"complete unilateral aplasia of the Mullerian ducts","type":"exact"},{"name":"complete unilateral aplasia of the Müllerian ducts","type":"exact"},{"name":"unicornuate uterus without rudimentary horn","type":"exact"}],"termid":"MONDO:0015832","xrefs":{"Monarch":{"xref_id":"0015832"}}}


id: MONDO:0016493
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete variant of Guillain-Barre syndrome (obsolete MONDO:0016493)","secondary_identifiers":["Orphanet:231413"],"synonyms":[{"name":"variant of GBS","type":"exact"},{"name":"variant of Guillain-Barré syndrome","type":"related"}],"termid":"MONDO:0016493","xrefs":{"Monarch":{"xref_id":"0016493"}}}


id: GO:0071100
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).","definition_xrefs":["PMID:11970960"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005886"],"is_obsolete":false,"name":"alphaV-beta8 integrin-MMP14-TGFbeta-1 complex","synonyms":[{"name":"ITGAV-ITGB8-MMP14-TGFB1 complex","type":"narrow"}],"termid":"GO:0071100"}


id: MONDO:0016554
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare endocrine disease characterized by the appearance of transient hypothyroidism, usually in preterm newborns, following long or short-term topical iodine exposure. Parenteral exposure from iodinated contrast agents may similarly alter thyroid function in term neonates.","definition_xrefs":["Orphanet:238688"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"transient congenital hypothyroidism due to neonatal factor","termid":"MONDO:0016556"},{"relation_name":"is_a","term_name":"endocrine system disorder","termid":"MONDO:0005151"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neonatal iodine exposure","secondary_identifiers":["GARD:20644","MEDGEN:1669806","UMLS:C4751432"],"synonyms":[{"name":"iodine antenatal exposure","type":"related"}],"termid":"MONDO:0016554","xrefs":{"Monarch":{"xref_id":"0016554"}}}


id: GO:0043058
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of locomotion","termid":"GO:0040012"},{"relation_name":"regulates","term_name":"backward locomotion","termid":"GO:0043057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of backward locomotion","termid":"GO:0043058"}


id: PATO:0001000
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001000 relative alternation (obsolete PATO:0001000)","termid":"PATO:0001000"}


id: PBO:0072499
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein SA pseudogene 28","termid":"PBO:0072499"}


id: PBO:0084829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial protein required for outer membrane protein import; involved in import of the subset of proteins with multiple alpha-helical transmembrane segments, including Ugo1p, Tom20p, and Fzo1p; component of a large protein complex in the outer membrane that includes Mim1p and functions as cation-selective channel for translocation of positively charged precursor segments; not essential in W303 strain background","termid":"PBO:0084829"}


id: PBO:0083005
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress","termid":"PBO:0083005"}


id: GO:0043467
data:
  {"annotated_genes":["SJAG_05314","SJAG_00963","SJAG_00685","SJAG_02592","SJAG_02433","SJAG_02785","SJAG_01376","SJAG_05006","SJAG_01062","SJAG_00698"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79207,77530],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045719"},{"annotations":[73408,76377],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045820"},{"annotations":[96907],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001172"},{"annotations":[90033],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905857"},{"annotations":[109997,94713,97950,112189],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903715"},{"annotations":[70420],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006110"},{"annotations":[76376],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043456"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of metabolic process","termid":"GO:0019222"},{"relation_name":"regulates","term_name":"generation of precursor metabolites and energy","termid":"GO:0006091"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00685":null,"SJAG_00698":null,"SJAG_00963":null,"SJAG_01062":null,"SJAG_01376":null,"SJAG_02433":null,"SJAG_02592":null,"SJAG_02785":null,"SJAG_05006":null,"SJAG_05314":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006091"],"is_obsolete":false,"name":"regulation of generation of precursor metabolites and energy","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-163685"],"termid":"GO:0043467","terms_by_termid":{"GO:0006110":null,"GO:0043456":null,"GO:0045719":null,"GO:0045820":null,"GO:1903715":null,"GO:1905857":null,"GO:2001172":null}}


id: MONDO:0012083
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the GRHL2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 28","secondary_identifiers":["MEDGEN:324846","MESH:C563890","DOID:0110557","GARD:18124","OMIM:608641","UMLS:C1837640"],"synonyms":[{"name":"DFNA28","type":"narrow"},{"name":"GRHL2 autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"autosomal dominant deafness 28","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 28","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in GRHL2","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 28","type":"narrow"},{"name":"deafness, autosomal dominant 28","type":"narrow"},{"name":"deafness, autosomal dominant type 28","type":"narrow"}],"termid":"MONDO:0012083","xrefs":{"Monarch":{"xref_id":"0012083"}}}


id: GO:0072058
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"renal outer medulla development","termid":"GO:0072054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"outer stripe development","termid":"GO:0072058"}


id: MONDO:0000823
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete MONDO:0000823 (obsolete MONDO:0000823)","termid":"MONDO:0000823","xrefs":{"Monarch":{"xref_id":"0000823"}}}


id: PBO:0017058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sSchizosaccharomyces pombe specific protein, similar to a region of alpha-galactosidase","termid":"PBO:0017058"}


id: PBO:0072788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sarcoma antigen 3, pseudogene","termid":"PBO:0072788"}


id: PBO:0050137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 47","termid":"PBO:0050137"}


id: PBO:0027869
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_duration_of_mitosis","termid":"PBO:0027869"}


id: MONDO:0008127
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ophthalmomandibulomelic dysplasia is characterized by complete blindness due to corneal opacities, difficult mastication due to temporomandibular fusion and anomalies of the arms.","definition_xrefs":["Orphanet:2741"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete syndromic corneal dystrophy (obsolete MONDO:0020215)","termid":"MONDO:0020215"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ophthalmomandibulomelic dysplasia","secondary_identifiers":["icd11.foundation:869046719","MESH:C563501","UMLS:C1833872","GARD:4365","OMIM:164900","MEDGEN:331604","SCTID:715484003"],"synonyms":[{"name":"OMM syndrome","type":"exact"},{"name":"Ophthalmo-mandibulo-melic dysplasia","type":"related"},{"name":"Pillay syndrome","type":"exact"},{"name":"ophthalmomandibulomelic dysplasia","type":"exact"}],"termid":"MONDO:0008127","xrefs":{"Monarch":{"xref_id":"0008127"}}}


id: PATO:0002284
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A physical quality that pertains by virtue of a pulling force that is directed away from the bearer and attempts to stretch or elongate the bearer.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"physical quality","termid":"PATO:0001018"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tension","termid":"PATO:0002284"}


id: GO:0098913
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.","definition_xrefs":["GOC:dph","GOC:mtg_cardiac_conduct_nov11","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane depolarization during cardiac muscle cell action potential","termid":"GO:0086012"},{"relation_name":"part_of","term_name":"ventricular cardiac muscle cell action potential","termid":"GO:0086005"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"membrane depolarization during ventricular cardiac muscle cell action potential","synonyms":[{"name":"electrocardiogram QRS complex","type":"related"},{"name":"ventricular depolarization","type":"related"}],"termid":"GO:0098913"}


id: FYPO:0006933
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of butylated hydroxytoluene (dibutylhydroxytoluene; BHT) than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002682","FYPO:0000139","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"resistance to butylated hydroxytoluene","synonyms":[{"name":"resistance to 2,6-di-tert-butyl-4-methylphenol","type":"exact"},{"name":"resistance to BHT","type":"exact"},{"name":"resistance to butylated hydroxytoluene during mitotic cell cycle","type":"related"},{"name":"resistance to butylated hydroxytoluene during vegetative growth","type":"exact"},{"name":"resistance to dibutylhydroxytoluene","type":"exact"},{"name":"resistant to BHT","type":"exact"},{"name":"resistant to butylated hydroxytoluene","type":"exact"}],"termid":"FYPO:0006933"}


id: PBO:0059888
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND1 pseudogene 11","termid":"PBO:0059888"}


id: FYPO:0001045
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of acid phosphatase activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal acid phosphatase activity","termid":"FYPO:0001044"},{"relation_name":"is_a","term_name":"decreased phosphatase activity","termid":"FYPO:0004304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0000661","FYPO:0000707","FYPO:0000652","FYPO:0001985","FYPO:0000654"],"is_obsolete":false,"name":"decreased acid phosphatase activity","synonyms":[{"name":"reduced acid phosphatase activity","type":"exact"}],"termid":"FYPO:0001045"}


id: GO:0102444
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine = 3,3'-O-dimethylquercetin + H+ + S-adenosyl-L-homocysteine.","definition_xrefs":["RHEA:74759"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methyltransferase activity","termid":"GO:0008168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0003674","GO:0016741"],"is_obsolete":false,"name":"isorhamnetin 3-O-methyltransferase activity","secondary_identifiers":["MetaCyc:RXN-13929"],"termid":"GO:0102444"}


id: GO:0060214
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.","definition_xrefs":["PMID:17722983","GOC:dph","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"endocardium morphogenesis","termid":"GO:0003160"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endocardium formation","termid":"GO:0060214"}


id: PBO:0060608
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NCBP2 antisense 2 (head to head)","termid":"PBO:0060608"}


id: PBO:0116544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc binding alcohol dehydrogenase family, unknown pathway","termid":"PBO:0116544"}


id: GO:0014874
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.","definition_xrefs":["GOC:mtg_muscle","GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to stimulus","termid":"GO:0050896"},{"relation_name":"part_of","term_name":"regulation of muscle adaptation","termid":"GO:0043502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to stimulus involved in regulation of muscle adaptation","synonyms":[{"name":"response to stimulus involved in regulation of muscle plasticity","type":"related"}],"termid":"GO:0014874"}


id: GO:0038002
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other.","definition_xrefs":["ISBN:3527303782","GOC:mtg_signaling_feb11","ISBN:0199264678"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell signaling","termid":"GO:0007267"},{"relation_name":"part_of","term_name":"endocrine process","termid":"GO:0050886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"endocrine signaling","synonyms":[{"name":"endocrine signalling","type":"exact"}],"termid":"GO:0038002"}


id: PBO:0043791
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CPEB2 divergent transcript","termid":"PBO:0043791"}


id: PBO:0056128
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysosomal trafficking regulator","termid":"PBO:0056128"}


id: PBO:0083127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"D-ribulokinase; carbohydrate kinase that specifically converts D-ribulose to D-ribulose 5-phosphate during pentose metabolism; null mutant accumulates D-ribulose and the precursor ribitol; proposed to function as a D-ribulose metabolic repair enzyme; member of the FGGY family of carbohydrate kinases; human homolog, FGGY, is involved in both D-ribulose and ribitol metabolism; human FGGY has been linked to both sporadic amyotrophic lateral sclerosis and bipolar disorder","termid":"PBO:0083127"}


id: PBO:0075913
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ST13, Hsp70 interacting protein pseudogene 5","termid":"PBO:0075913"}


id: GO:0160158
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A protein complex that catalyzes the oxidative decarboxylation of branched-chain alpha-keto acids derived from L-leucine, L-isoleucine, and L-valine to branched-chain acyl-CoAs. It is composed of four polypeptides, E1alpha, E1beta, E2, and E3.","definition_xrefs":["PMID:10464218"],"gene_count":0,"genotype_count":0,"name":"obsolete cytosolic branched-chain alpha-keto acid dehydrogenase complex (obsolete GO:0160158)","synonyms":[{"name":"BKDH complex","type":"exact"}],"termid":"GO:0160158"}


id: GO:1901141
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of lignin biosynthetic process.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of secondary metabolite biosynthetic process","termid":"GO:1900376"},{"relation_name":"is_a","term_name":"regulation of phenylpropanoid metabolic process","termid":"GO:2000762"},{"relation_name":"regulates","term_name":"lignin biosynthetic process","termid":"GO:0009809"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"regulation of lignin biosynthetic process","synonyms":[{"name":"regulation of lignin anabolism","type":"exact"},{"name":"regulation of lignin biosynthesis","type":"exact"},{"name":"regulation of lignin formation","type":"exact"},{"name":"regulation of lignin synthesis","type":"exact"}],"termid":"GO:1901141"}


id: PBO:0113533
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar membrane protein; required for efflux of amino acids during autophagic body breakdown in vacuole; targeted to vacuole via AP-3 pathway; null mutation causes gradual loss of viability during starvation","termid":"PBO:0113533"}


id: GO:0051620
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"norepinephrine transport","termid":"GO:0015874"},{"relation_name":"is_a","term_name":"catecholamine uptake","termid":"GO:0090493"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"norepinephrine uptake","synonyms":[{"name":"levarterenol reuptake","type":"exact"},{"name":"levarterenol uptake","type":"exact"},{"name":"noradrenaline reuptake","type":"exact"},{"name":"noradrenaline uptake","type":"exact"},{"name":"norepinephrine import","type":"exact"},{"name":"norepinephrine reuptake","type":"exact"}],"termid":"GO:0051620"}


id: GO:0102695
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + cis-zeatin-7-N-glucoside + UDP.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity (obsolete GO:0102695)","termid":"GO:0102695"}


id: GO:0080030
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + methyl (indol-3-yl)acetate = (indol-3-yl)acetate + H+ + methanol.","definition_xrefs":["RHEA:32919","PMID:18467465"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0003674","GO:0016788"],"is_obsolete":false,"name":"methyl indole-3-acetate esterase activity","secondary_identifiers":["MetaCyc:RXN-10711"],"synonyms":[{"name":"MeIAA esterase activity","type":"exact"},{"name":"Methyl IAA esterase activity","type":"exact"},{"name":"indole-3-Acetic acid methyl ester esterase activity","type":"exact"}],"termid":"GO:0080030"}


id: PBO:0070532
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L6 pseudogene 31","termid":"PBO:0070532"}


id: GO:0062242
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.","definition_xrefs":["PMID:22440839"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell cytoplasmic vesicle membrane","termid":"GO:0044162"},{"relation_name":"part_of","term_name":"double membrane vesicle viral factory","termid":"GO:0039718"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"double membrane vesicle viral factory membrane","synonyms":[{"name":"membrane of double membrane vesicle viral factory","type":"exact"}],"termid":"GO:0062242"}


id: PBO:0091587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyoxylase III Sdj1","termid":"PBO:0091587"}


id: MONDO:0033636
data:
  {"annotated_genes":["SJAG_04553"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86083],"is_not":false,"summary":null,"term":"MONDO:0033636"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial complex IV deficiency, nuclear-type","termid":"MONDO:0033885"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04553":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"mitochondrial complex 4 deficiency, nuclear type 4","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:619048","GARD:16405","DOID:0070493","UMLS:C5436683","MEDGEN:1748100"],"synonyms":[{"name":"MC4DN4","type":"exact"},{"name":"mitochondrial complex IV deficiency, nuclear type 4","type":"exact"}],"termid":"MONDO:0033636","terms_by_termid":{"MONDO:0033636":null},"xrefs":{"Monarch":{"xref_id":"0033636"}}}


id: GO:0006889
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the concentration of calcium in the endoplasmic reticulum.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of calcium in ER (obsolete GO:0006889)","synonyms":[{"name":"regulation of calcium in ER","type":"exact"}],"termid":"GO:0006889"}


id: PR:O74551
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC777.12c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74551"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C777.12c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC777.12c","synonyms":[{"name":"Spom972h-SPCC777.12c","type":"exact"}],"termid":"PR:O74551"}


id: GO:0042490
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.","definition_xrefs":["CL:0000199","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron differentiation","termid":"GO:0030182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mechanoreceptor differentiation","termid":"GO:0042490"}


id: MONDO:0001060
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An invasive adenocarcinoma confined to the mucosa or mucosa and submucosa of the gastric wall. The regional lymph nodes may or may not be involved. It usually occurs in the lesser curvature. The 5-year survival rate following resection is between 80 percent and 95 percent, and remains high even when lymph node metastases are present.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gastric adenocarcinoma","termid":"MONDO:0005036"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"microinvasive gastric cancer","secondary_identifiers":["SCTID:276809004","MEDGEN:138098","UMLS:C0349530","DOID:10541","NCIT:C27131"],"synonyms":[{"name":"EGC","type":"exact"},{"name":"early gastric cancer","type":"exact"},{"name":"superficial gastric cancer","type":"exact"},{"name":"superficial spreading gastric cancer","type":"exact"},{"name":"surface gastric cancer","type":"exact"}],"termid":"MONDO:0001060","xrefs":{"Monarch":{"xref_id":"0001060"}}}


id: GO:0032287
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myelin maintenance","termid":"GO:0043217"},{"relation_name":"part_of","term_name":"myelination in peripheral nervous system","termid":"GO:0022011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"peripheral nervous system myelin maintenance","synonyms":[{"name":"myelin maintenance in peripheral nervous system","type":"exact"},{"name":"peripheral nervous system myelin sheath maintenance","type":"exact"}],"termid":"GO:0032287"}


id: PBO:0031258
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_mitotic_cell_cycle_DNA_replication_checkpoint","termid":"PBO:0031258"}


id: MONDO:0017747
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of protein O-glycosylation","termid":"MONDO:0017741"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0024322"],"is_obsolete":false,"name":"disorder of fucoglycosan synthesis","secondary_identifiers":["MEDGEN:1843205","UMLS:C5681046","Orphanet:309505","GARD:21341"],"termid":"MONDO:0017747","xrefs":{"Monarch":{"xref_id":"0017747"}}}


id: PBO:0042632
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromodomain Y-linked 7 pseudogene","termid":"PBO:0042632"}


id: PBO:0086123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for fermentation at low temperature; plays a role in the maturation of secretory proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","termid":"PBO:0086123"}


id: PBO:0028339
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-altered_DNA_level","termid":"PBO:0028339"}


id: PR:O74501
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- trs130 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74501"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein CC285.14 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC285.14","synonyms":[{"name":"Spom972h-trs130","type":"exact"}],"termid":"PR:O74501"}


id: GO:0090675
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.","definition_xrefs":["GOC:lb","PMID:24725409"],"direct_ancestors":[{"relation_name":"is_a","term_name":"homotypic cell-cell adhesion","termid":"GO:0034109"},{"relation_name":"part_of","term_name":"brush border assembly","termid":"GO:1904970"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0007155"],"is_obsolete":false,"name":"intermicrovillar adhesion","termid":"GO:0090675"}


id: PBO:0011070
data:
  {"annotation_feature_type":"gene","cv_name":"species_dist","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved in vertebrates","termid":"PBO:0011070"}


id: MONDO:0060589
data:
  {"annotated_genes":["SJAG_04003"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85580],"is_not":false,"summary":null,"term":"MONDO:0060589"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04003":null},"genotype_count":0,"is_obsolete":false,"name":"facial palsy, congenital, with ptosis and velopharyngeal dysfunction","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4540277","MEDGEN:1623077","OMIM:617732"],"synonyms":[{"name":"FPVEPD","type":"related"},{"name":"facial palsy, congenital, with ptosis and velopharyngeal dysfunction","type":"exact"},{"name":"facial palsy, congenitla, with ptosis and velopharyngeal dysfunction","type":"exact"}],"termid":"MONDO:0060589","terms_by_termid":{"MONDO:0060589":null},"xrefs":{"Monarch":{"xref_id":"0060589"}}}


id: PBO:0016916
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Septum Promoting GTPase","termid":"PBO:0016916"}


id: FYPO:0002959
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of RNA measured in a cell is lower than normal during one or both meiotic nuclear divisions. Total RNA or a specific RNA may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased RNA level during meiotic cell cycle","termid":"FYPO:0004630"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0006551","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased RNA level during meiosis","synonyms":[{"name":"decreased RNA accumulation during meiosis","type":"related"},{"name":"decreased RNA level during meiotic nuclear division","type":"exact"},{"name":"decreased transcript level during meiosis","type":"exact"},{"name":"reduced RNA level during meiosis","type":"exact"}],"termid":"FYPO:0002959"}


id: PBO:0029519
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_morphology_viable_vegetative_cell_population_(obsolete_FYPO:0002195)","termid":"PBO:0029519"}


id: PATO:0000820
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000820 absolute taste acuity value (obsolete PATO:0000820)","termid":"PATO:0000820"}


id: MONDO:0006334
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete ovarian embryonal carcinoma (obsolete MONDO:0006334)","termid":"MONDO:0006334","xrefs":{"Monarch":{"xref_id":"0006334"}}}


id: GO:0043708
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.","definition_xrefs":["GOC:dph","GOC:jl","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-substrate adhesion","termid":"GO:0031589"},{"relation_name":"part_of","term_name":"submerged biofilm formation","termid":"GO:0090605"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"cell adhesion involved in biofilm formation","synonyms":[{"name":"cell adhesion during biofilm formation","type":"related"}],"termid":"GO:0043708"}


id: MONDO:0017779
data:
  {"annotated_genes":["SJAG_02949"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85527],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012221"},{"annotations":[85530],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012222"}]},"cv_name":"mondo","definition":"Alpha-N-acetylgalactosaminidase (NAGA) deficiency is a very rare lysosomal storage disease that is clinically and pathologically heterogeneous and is characterized by deficient NAGA activity.","definition_xrefs":["Orphanet:3137"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oligosaccharidosis","termid":"MONDO:0019251"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02949":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0002561","MONDO:0005066"],"is_obsolete":false,"name":"alpha-N-acetylgalactosaminidase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1647881428","ICD9:277.89","NANDO:1200134","SCTID:238048001","NORD:1693","UMLS:C5848084","GARD:16621","DOID:0112317","MEDGEN:1845666"],"synonyms":[{"name":"NAGA deficiency","type":"exact"},{"name":"Schindler disease","type":"exact"},{"name":"alpha-N-acetylgalactosaminidase activity disease","type":"exact"},{"name":"disorder of alpha-N-acetylgalactosaminidase activity","type":"exact"}],"termid":"MONDO:0017779","terms_by_termid":{"MONDO:0012221":null,"MONDO:0012222":null},"xrefs":{"Monarch":{"xref_id":"0017779"}}}


id: PBO:0091810
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Required for Stationary phase Viability","termid":"PBO:0091810"}


id: PBO:0005777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U5 snRNP-associated protein Prp18 (predicted)","termid":"PBO:0005777"}


id: PBO:0005841
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thymidylate kinase Tmp1","termid":"PBO:0005841"}


id: PBO:0058594
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6726","termid":"PBO:0058594"}


id: GO:0002581
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of antigen processing and presentation","termid":"GO:0002578"},{"relation_name":"is_a","term_name":"regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","termid":"GO:0002580"},{"relation_name":"negatively_regulates","term_name":"antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","termid":"GO:0002504"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","synonyms":[{"name":"down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","type":"exact"},{"name":"down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","type":"exact"},{"name":"downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","type":"exact"},{"name":"inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","type":"narrow"},{"name":"negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II","type":"exact"}],"termid":"GO:0002581"}


id: PBO:0088478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sister chromatid separation inhibitor, securin","termid":"PBO:0088478"}


id: GO:0006177
data:
  {"annotated_genes":["SJAG_01298","SJAG_06634","SJAG_04634","SJAG_00964"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[59501,63136,75080],"is_not":false,"summary":null,"term":"GO:0006177"},{"annotations":[75995],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032263"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine ribonucleotide biosynthetic process","termid":"GO:0009152"},{"relation_name":"is_a","term_name":"purine ribonucleoside monophosphate biosynthetic process","termid":"GO:0009168"},{"relation_name":"is_a","term_name":"GMP metabolic process","termid":"GO:0046037"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00964":null,"SJAG_01298":null,"SJAG_04634":null,"SJAG_06634":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0055086","GO:0044281"],"is_obsolete":false,"name":"GMP biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000108":null},"synonyms":[{"name":"GMP anabolism","type":"exact"},{"name":"GMP biosynthesis","type":"exact"},{"name":"GMP formation","type":"exact"},{"name":"GMP synthesis","type":"exact"}],"termid":"GO:0006177","terms_by_termid":{"GO:0006177":null,"GO:0032263":null}}


id: GO:1990092
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.","definition_xrefs":["PMID:20460380"],"direct_ancestors":[{"relation_name":"is_a","term_name":"self proteolysis","termid":"GO:0097264"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"calcium-dependent self proteolysis","termid":"GO:1990092"}


id: PBO:0075428
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sperm associated antigen 17","termid":"PBO:0075428"}


id: PBO:0052513
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kelch like family member 26","termid":"PBO:0052513"}


id: GO:0015704
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"one-carbon compound transport","termid":"GO:0019755"},{"relation_name":"is_a","term_name":"nitrogen compound transport","termid":"GO:0071705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"cyanate transport","termid":"GO:0015704"}


id: PBO:0050696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family A (Hsp70) member 9 pseudogene 2","termid":"PBO:0050696"}


id: MONDO:0018766
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"intestinal disorder","termid":"MONDO:0005020"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"chronic enteropathy associated with SLCO2A1 gene","secondary_identifiers":["NANDO:2100261","MEDGEN:1800261","GARD:21946","NANDO:2200925","Orphanet:468641","UMLS:C5568838"],"synonyms":[{"name":"CEAS","type":"exact"}],"termid":"MONDO:0018766","xrefs":{"Monarch":{"xref_id":"0018766"}}}


id: MONDO:0008056
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Steinert disease, also known as myotonic dystrophy type 1, is a muscle disease characterized by myotonia and by multiorgan damage that combines various degrees of muscle weakness, arrhythmia and/or cardiac conduction disorders, cataract, endocrine damage, sleep disorders and baldness.","definition_xrefs":["Orphanet:273"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete neuro-ophthalmological disease (obsolete MONDO:0015368)","termid":"MONDO:0015368"},{"relation_name":"is_a","term_name":"myotonic dystrophy","termid":"MONDO:0016107"},{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0005267"],"is_obsolete":false,"name":"myotonic dystrophy type 1","secondary_identifiers":["UMLS:C3250443","MEDGEN:886881","ICD9:359.21","NORD:1075","DOID:11722","GARD:8310","NCIT:C84679","OMIM:160900","icd11.foundation:557405480"],"synonyms":[{"name":"DM1","type":"exact"},{"name":"DMPK myotonic dystrophy","type":"exact"},{"name":"MD1","type":"exact"},{"name":"Myotonic Dystrophy","type":"exact"},{"name":"Steinert disease","type":"exact"},{"name":"Steinert myotonic dystrophy","type":"related"},{"name":"Steinert myotonic dystrophy syndrome","type":"exact"},{"name":"Steinert syndrome","type":"exact"},{"name":"Steinert's disease","type":"related"},{"name":"dystrophia myotonica","type":"exact"},{"name":"dystrophia myotonica 1","type":"related"},{"name":"dystrophia myotonica type 1","type":"related"},{"name":"myotonic dystrophy 1","type":"related"},{"name":"myotonic dystrophy caused by mutation in DMPK","type":"exact"},{"name":"myotonic dystrophy of Steinert","type":"exact"},{"name":"myotonic dystrophy type 1","type":"exact"}],"termid":"MONDO:0008056","xrefs":{"Monarch":{"xref_id":"0008056"}}}


id: MONDO:0013687
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive cerebellar ataxia-epilepsy-intellectual disability syndrome due to WWOX deficiency is a rare autosomal recessive cerebellar ataxia-epilepsy-intellectual disability syndrome characterized by early-childhood onset of cerebellar ataxia associated with generalized tonic-clonic epilepsy and psychomotor development delay, dysarthria, gaze-evoked nystagmus and learning disability. Other features in some patients include upper motor neuron signs with leg spasticity and extensor plantar responses, and mild cerebellar atrophy on brain MRI.","definition_xrefs":["Orphanet:284282"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive cerebellar ataxia - epilepsy - intellectual disability syndrome","termid":"MONDO:0018446"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027","MONDO:0005559","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive spinocerebellar ataxia 12","secondary_identifiers":["GARD:17313","MEDGEN:482082","OMIM:614322","UMLS:C3280452","DOID:0080060"],"synonyms":[{"name":"SCAR12","type":"exact"},{"name":"WWOX autosomal recessive cerebellar ataxia - epilepsy - intellectual disability syndrome","type":"exact"},{"name":"WWOX autosomal recessive cerebellar ataxia-epilepsy-intellectual disability syndrome","type":"exact"},{"name":"autosomal recessive cerebellar ataxia - epilepsy - intellectual disability syndrome caused by mutation in WWOX","type":"exact"},{"name":"autosomal recessive cerebellar ataxia - epilepsy - intellectual disability syndrome due to WWOX deficiency","type":"related"},{"name":"autosomal recessive cerebellar ataxia-epilepsy-intellectual disability syndrome caused by mutation in WWOX","type":"exact"},{"name":"autosomal recessive spinocerebellar ataxia 12","type":"exact"},{"name":"autosomal recessive spinocerebellar ataxia type 12","type":"exact"},{"name":"spinocerebellar ataxia with intellectual disability and epilepsy","type":"related"},{"name":"spinocerebellar ataxia with mental retardation and epilepsy","type":"related"},{"name":"spinocerebellar ataxia, autosomal recessive 12","type":"related"},{"name":"spinocerebellar ataxia, autosomal recessive type 12","type":"exact"}],"termid":"MONDO:0013687","xrefs":{"Monarch":{"xref_id":"0013687"}}}


id: PBO:0034501
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_UV_during_late_mitotic_G2_phase","termid":"PBO:0034501"}


id: PBO:0076547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TatD DNase domain containing 1 pseudogene 1","termid":"PBO:0076547"}


id: GO:0022002
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell.","definition_xrefs":["GOC:jid","GOC:tb","GOC:cls","GOC:dph","GO_REF:0000021","GOC:dgh"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway (obsolete GO:0022002)","synonyms":[{"name":"Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate","type":"exact"},{"name":"Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate","type":"exact"},{"name":"Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate","type":"exact"},{"name":"Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate","type":"narrow"},{"name":"Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate","type":"exact"},{"name":"Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate","type":"exact"},{"name":"negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway","type":"exact"},{"name":"negative regulation of anterior neural cell fate commitment of the neural plate by Wnt-activated signaling pathway","type":"exact"}],"termid":"GO:0022002"}


id: FYPO:0002342
data:
  {"alleles_by_uniquename":{"SJAG_00118:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00118","name":"mid2delta","uniquename":"SJAG_00118:allele-1"},"SJAG_01143:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01143","name":"mid1delta","uniquename":"SJAG_01143:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"multi_locus_phenotype":[{"annotations":[119851],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000118"}],"single_locus_phenotype":[{"annotations":[119840,119841],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0000118"}]},"cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the cell contains one or more septa.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"septated cell","termid":"FYPO:0004296"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00118":null,"SJAG_01143":null},"genotype_count":3,"genotypes_by_uniquename":{"mid1delta":{"display_name":"mid1delta","display_uniquename":"mid1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]}]},"mid1delta__mid2delta":{"display_name":"mid1delta mid2delta","display_uniquename":"mid1delta__mid2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_00118:allele-1","expression":"Null"}]}]},"mid2delta":{"display_name":"mid2delta","display_uniquename":"mid2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00118:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"multi_locus_annotated_genes":["SJAG_01143","SJAG_00118"],"name":"septated vegetative cell","references_by_uniquename":{"PMID:25866389":null},"single_locus_annotated_genes":["SJAG_00118","SJAG_01143"],"single_locus_genotype_uniquenames":["mid1delta","mid2delta"],"synonyms":[{"name":"septated cell during mitotic cell cycle","type":"related"},{"name":"septated cell during vegetative growth","type":"exact"},{"name":"septum present during vegetative growth","type":"exact"}],"termid":"FYPO:0002342","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000137":null,"FYPO:0000118":null}}


id: PBO:0012286
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Golgi membrane protein involved in vesicle-mediated transport (predicted)","termid":"PBO:0012286"}


id: PBO:0080040
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin specific peptidase 17 like family member 26","termid":"PBO:0080040"}


id: MONDO:0011931
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"ovarian cancer","termid":"MONDO:0008170"},{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovarian cancer, susceptibility to, 1","secondary_identifiers":["MEDGEN:390836","OMIM:607893","UMLS:C2675601"],"synonyms":[{"name":"OVCAS1","type":"exact"},{"name":"ovarian cancer, susceptibility to","type":"exact"},{"name":"ovarian cancer, susceptibility to, 1","type":"exact"}],"termid":"MONDO:0011931","xrefs":{"Monarch":{"xref_id":"0011931"}}}


id: PBO:0059956
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND3 pseudogene 1","termid":"PBO:0059956"}


id: GO:0031527
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The portion of the plasma membrane surrounding a filopodium.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell projection membrane","termid":"GO:0031253"},{"relation_name":"part_of","term_name":"filopodium","termid":"GO:0030175"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005886"],"is_obsolete":false,"name":"filopodium membrane","termid":"GO:0031527"}


id: PBO:0077015
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombospondin 3","termid":"PBO:0077015"}


id: GO:0031676
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The pigmented membrane of a plasma membrane-derived thylakoid.","definition_xrefs":["GOC:mah","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thylakoid membrane","termid":"GO:0042651"},{"relation_name":"is_a","term_name":"plasma membrane-derived chromatophore membrane","termid":"GO:0042717"},{"relation_name":"is_a","term_name":"plasma membrane region","termid":"GO:0098590"},{"relation_name":"part_of","term_name":"bacterial thylakoid","termid":"GO:0030075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005737","GO:0005575","GO:0005886"],"is_obsolete":false,"name":"plasma membrane-derived thylakoid membrane","synonyms":[{"name":"plasma membrane thylakoid membrane","type":"exact"}],"termid":"GO:0031676"}


id: GO:0140763
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates.","definition_xrefs":["PMID:18708581"],"direct_ancestors":[{"relation_name":"is_a","term_name":"programmed DNA elimination","termid":"GO:0031049"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"programmed DNA elimination by elimination of internal DNA segments","termid":"GO:0140763"}


id: GO:0008248
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. An activity involved in the removal of an intron from a pre-mRNA.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete pre-mRNA splicing factor activity (obsolete GO:0008248)","synonyms":[{"name":"pre-mRNA splicing factor activity","type":"exact"}],"termid":"GO:0008248"}


id: PBO:0089624
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial iron-sulfur cluster exporter Atm1","termid":"PBO:0089624"}


id: PBO:0061777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"OCA2 melanosomal transmembrane protein","termid":"PBO:0061777"}


id: PBO:0116249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved fungal protein, possible RNA binding, possible nuclease inhibitor, low similarity to ribosomal protein L3","termid":"PBO:0116249"}


id: GO:0002638
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of immunoglobulin production","termid":"GO:0002637"},{"relation_name":"is_a","term_name":"negative regulation of production of molecular mediator of immune response","termid":"GO:0002701"},{"relation_name":"negatively_regulates","term_name":"immunoglobulin production","termid":"GO:0002377"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of immunoglobulin production","secondary_identifiers":["GO:0002641","GO:0051025"],"synonyms":[{"name":"down regulation of immunoglobulin production","type":"exact"},{"name":"down-regulation of immunoglobulin production","type":"exact"},{"name":"downregulation of immunoglobulin production","type":"exact"},{"name":"inhibition of immunoglobulin production","type":"narrow"},{"name":"negative regulation of immunoglobulin biosynthetic process","type":"narrow"},{"name":"negative regulation of immunoglobulin secretion","type":"narrow"}],"termid":"GO:0002638"}


id: FYPO:0000423
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of endocytosis is decreased. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal endocytosis during vegetative growth","termid":"FYPO:0000034"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"decreased rate of endocytosis during vegetative growth","synonyms":[{"name":"decreased rate of actin-mediated endocytosis during vegetative growth","type":"exact"},{"name":"decreased rate of endocytosis during mitotic cell cycle","type":"related"},{"name":"decreased rate of protein internalization during vegetative growth","type":"narrow"},{"name":"endocytosis: decreased rate during vegetative growth","type":"related"},{"name":"reduced rate of endocytosis during vegetative growth","type":"exact"}],"termid":"FYPO:0000423"}


id: GO:0072633
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.","definition_xrefs":["PMID:30328794","GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine production","termid":"GO:0001816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"interleukin-30 production","secondary_identifiers":["GO:0072634"],"synonyms":[{"name":"IL-30 production","type":"exact"},{"name":"interleukin-30 complex production","type":"exact"},{"name":"interleukin-30 secretion","type":"narrow"}],"termid":"GO:0072633"}


id: MONDO:0958192
data:
  {"annotated_genes":["SJAG_02901"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86752],"is_not":false,"summary":null,"term":"MONDO:0958192"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"glycine encephalopathy","termid":"MONDO:0011612"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02901":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"glycine encephalopathy 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5830559","OMIM:620398","MEDGEN:1841195"],"termid":"MONDO:0958192","terms_by_termid":{"MONDO:0958192":null},"xrefs":{"Monarch":{"xref_id":"0958192"}}}


id: PBO:0036231
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell surface glycoprotein, flocculin Pfl8","termid":"PBO:0036231"}


id: PBO:0017695
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial translation release factor","termid":"PBO:0017695"}


id: PBO:0031204
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_during_cellular_response_to_high_osmolarity","termid":"PBO:0031204"}


id: GO:1900916
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of olefin biosynthetic process","termid":"GO:1900913"},{"relation_name":"is_a","term_name":"regulation of octadecene biosynthetic process","termid":"GO:1900914"},{"relation_name":"is_a","term_name":"positive regulation of octadecene metabolic process","termid":"GO:1900919"},{"relation_name":"positively_regulates","term_name":"octadecene biosynthetic process","termid":"GO:1900682"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of octadecene biosynthetic process","synonyms":[{"name":"activation of 1-octadecene biosynthetic process","type":"related"},{"name":"activation of octadecene anabolism","type":"related"},{"name":"activation of octadecene biosynthesis","type":"related"},{"name":"activation of octadecene biosynthetic process","type":"narrow"},{"name":"activation of octadecene formation","type":"related"},{"name":"activation of octadecene synthesis","type":"related"},{"name":"positive regulation of 1-octadecene biosynthetic process","type":"related"},{"name":"positive regulation of octadecene anabolism","type":"related"},{"name":"positive regulation of octadecene biosynthesis","type":"related"},{"name":"positive regulation of octadecene formation","type":"related"},{"name":"positive regulation of octadecene synthesis","type":"related"},{"name":"up regulation of 1-octadecene biosynthetic process","type":"related"},{"name":"up regulation of octadecene anabolism","type":"related"},{"name":"up regulation of octadecene biosynthesis","type":"related"},{"name":"up regulation of octadecene biosynthetic process","type":"exact"},{"name":"up regulation of octadecene formation","type":"related"},{"name":"up regulation of octadecene synthesis","type":"related"},{"name":"up-regulation of 1-octadecene biosynthetic process","type":"related"},{"name":"up-regulation of octadecene anabolism","type":"related"},{"name":"up-regulation of octadecene biosynthesis","type":"related"},{"name":"up-regulation of octadecene biosynthetic process","type":"exact"},{"name":"up-regulation of octadecene formation","type":"related"},{"name":"up-regulation of octadecene synthesis","type":"related"},{"name":"upregulation of 1-octadecene biosynthetic process","type":"related"},{"name":"upregulation of octadecene anabolism","type":"related"},{"name":"upregulation of octadecene biosynthesis","type":"related"},{"name":"upregulation of octadecene biosynthetic process","type":"exact"},{"name":"upregulation of octadecene formation","type":"related"},{"name":"upregulation of octadecene synthesis","type":"related"}],"termid":"GO:1900916"}


id: PBO:0057501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 619","termid":"PBO:0057501"}


id: PBO:0044094
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cancer/testis antigen family 47 member A2","termid":"PBO:0044094"}


id: MONDO:0020154
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete microblepharon-ablephara syndrome (obsolete MONDO:0020154)","secondary_identifiers":["Orphanet:98563"],"termid":"MONDO:0020154","xrefs":{"Monarch":{"xref_id":"0020154"}}}


id: FYPO:0007005
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the frequency of DNA recombination downstream of replication fork barriers is decreased.","definition_xrefs":["PomBase:mah","PMID:30667359"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA recombination during vegetative growth","termid":"FYPO:0001345"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000293","FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"decreased DNA recombination downstream of mitotic DNA replication fork barriers","synonyms":[{"name":"decreased DNA recombination downstream of mitotic DNA replication fork barriers during mitotic cell cycle","type":"related"},{"name":"decreased DNA recombination downstream of mitotic DNA replication fork barriers during vegetative growth","type":"exact"},{"name":"decreased recombination downstream of mitotic DNA replication fork barriers","type":"exact"},{"name":"decreased template switching recombination downstream of mitotic DNA replication fork barriers","type":"exact"},{"name":"reduced DNA recombination downstream of mitotic DNA replication fork barriers","type":"exact"}],"termid":"FYPO:0007005"}


id: MONDO:0013544
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any familial atrial fibrillation in which the cause of the disease is a mutation in the GJA5 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial atrial fibrillation","termid":"MONDO:0018054"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"atrial fibrillation, familial, 11","secondary_identifiers":["UMLS:C3279693","OMIM:614049","MEDGEN:481323","GARD:15747"],"synonyms":[{"name":"ATFB11","type":"related"},{"name":"GJA5 familial atrial fibrillation","type":"exact"},{"name":"atrial fibrillation, familial, 11","type":"exact"},{"name":"atrial fibrillation, familial, type 11","type":"exact"},{"name":"familial atrial fibrillation caused by mutation in GJA5","type":"exact"}],"termid":"MONDO:0013544","xrefs":{"Monarch":{"xref_id":"0013544"}}}


id: PBO:0067400
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 507, pseudogene","termid":"PBO:0067400"}


id: SO:0000764
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000764 BAC_clone (obsolete SO:0000764)","termid":"SO:0000764"}


id: MONDO:0016163
data:
  {"annotated_genes":["SJAG_00087"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86259],"is_not":false,"summary":null,"term":"MONDO:0016163"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant cerebellar ataxia","termid":"MONDO:0020380"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00087":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0002039","MONDO:0005559","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant cerebellar ataxia type II","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0752125","OMIM:164500","DOID:0050958","NCIT:C126562","GARD:20405","Orphanet:208508","MEDGEN:156006","Orphanet:94147","SCTID:715726000"],"synonyms":[{"name":"ADCA, type II","type":"related"},{"name":"ADCA2","type":"exact"},{"name":"ADCAII","type":"exact"},{"name":"ATXN7 autosomal dominant cerebellar ataxia type II","type":"exact"},{"name":"Adca, type 2","type":"related"},{"name":"OPCA 3","type":"related"},{"name":"OPCA III","type":"related"},{"name":"OPCA with macular Degeneration and external ophthalmoplegia","type":"related"},{"name":"OPCA with retinal Degeneration","type":"related"},{"name":"OPCA3","type":"related"},{"name":"SCA7","type":"exact"},{"name":"ataxia with pigmentary retinopathy","type":"exact"},{"name":"autosomal dominant cerebellar ataxia type 2","type":"exact"},{"name":"autosomal dominant cerebellar ataxia type II","type":"exact"},{"name":"autosomal dominant cerebellar ataxia type II caused by mutation in ATXN7","type":"exact"},{"name":"autosomal dominant cerebellar ataxia, type 2","type":"related"},{"name":"cerebellar syndrome-pigmentary maculopathy syndrome","type":"exact"},{"name":"olivopontocerebellar atrophy 3","type":"related"},{"name":"spinocerebellar ataxia 7","type":"related"},{"name":"spinocerebellar ataxia type 7","type":"exact"}],"termid":"MONDO:0016163","terms_by_termid":{"MONDO:0016163":null},"xrefs":{"Monarch":{"xref_id":"0016163"}}}


id: GO:0031049
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing.","definition_xrefs":["GOC:mah","GOC:ns","PMID:18708581","PMID:32986476","PMID:24886889"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of gene expression","termid":"GO:0010629"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"programmed DNA elimination","termid":"GO:0031049"}


id: MONDO:0005540
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rectal adenocarcinoma (obsolete MONDO:0005540)","termid":"MONDO:0005540","xrefs":{"Monarch":{"xref_id":"0005540"}}}


id: PR:Q9USU3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fbh1 gene.","definition_xrefs":["UniProtKB:Q9USU3","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box DNA helicase protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC336.01","synonyms":[{"name":"Spom972h-fbh1","type":"exact"}],"termid":"PR:Q9USU3"}


id: PBO:0048534
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gem nuclear organelle associated protein 8","termid":"PBO:0048534"}


id: GO:0048574
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.","definition_xrefs":["GOC:pj","ISBN:0582015952","ISBN:0709408862","GOC:jid","ISBN:0697037754"],"direct_ancestors":[{"relation_name":"is_a","term_name":"long-day photoperiodism","termid":"GO:0048571"},{"relation_name":"is_a","term_name":"photoperiodism, flowering","termid":"GO:0048573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"long-day photoperiodism, flowering","synonyms":[{"name":"long-day photoperiodic control of flowering","type":"exact"},{"name":"long-day photoperiodic control of flowering time","type":"exact"},{"name":"long-day photoperiodic control of inflorescence development","type":"exact"},{"name":"response to long-day, flowering","type":"exact"},{"name":"response to short-night, flowering","type":"exact"},{"name":"short-night photoperiodism, flowering","type":"exact"}],"termid":"GO:0048574"}


id: PATO:0001766
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A cellular quality inhering in a cell by virtue of its anisotropic intracellular organization.","definition_xrefs":["PATOC:GVG"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001766 cellular polarity (obsolete PATO:0001766)","termid":"PATO:0001766"}


id: GO:1904274
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.","definition_xrefs":["PMID:4203962","GOC:mr","GO_REF:0000079","PMID:22640933","GOC:TermGenie","PMID:25097825"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tight junction assembly","termid":"GO:0120192"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"tricellular tight junction assembly","synonyms":[{"name":"tricellular tight junction formation","type":"exact"}],"termid":"GO:1904274"}


id: GO:0022885
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a bacteriocin from one side of a membrane to the other.","definition_xrefs":["ISBN:0815340729","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amide transmembrane transporter activity","termid":"GO:0042887"},{"relation_name":"is_a","term_name":"xenobiotic transmembrane transporter activity","termid":"GO:0042910"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"bacteriocin transmembrane transporter activity","termid":"GO:0022885"}


id: PBO:0086075
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression","termid":"PBO:0086075"}


id: MONDO:0024541
data:
  {"annotated_genes":["SJAG_03805"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86782],"is_not":false,"summary":null,"term":"MONDO:0024541"}]},"cv_name":"mondo","definition":"Any tricho-hepato-enteric syndrome in which the cause of the disease is a mutation in the TTC37 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trichohepatoenteric syndrome","termid":"MONDO:0009105"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03805":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0005046"],"is_obsolete":false,"name":"trichohepatoenteric syndrome 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1644087","OMIM:222470","UMLS:C4551982","DOID:0111415"],"synonyms":[{"name":"THES1","type":"related"},{"name":"TRICHOHEPATOENTERIC syndrome 1","type":"exact"},{"name":"TTC37 tricho-hepato-enteric syndrome","type":"exact"},{"name":"The syndrome","type":"related"},{"name":"diarrhea, fatal infantile, with trichorrhexis nodosa","type":"related"},{"name":"diarrhea, syndromic","type":"related"},{"name":"tricho-hepato-enteric syndrome caused by mutation in TTC37","type":"exact"},{"name":"trichohepatoenteric syndrome 1","type":"exact"}],"termid":"MONDO:0024541","terms_by_termid":{"MONDO:0024541":null},"xrefs":{"Monarch":{"xref_id":"0024541"}}}


id: GO:0060028
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.","definition_xrefs":["GOC:dph","PMID:12062082"],"direct_ancestors":[{"relation_name":"is_a","term_name":"convergent extension","termid":"GO:0060026"},{"relation_name":"part_of","term_name":"axis elongation","termid":"GO:0003401"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"convergent extension involved in axis elongation","termid":"GO:0060028"}


id: FYPO:0002145
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to diethyl maleate (DEM), a compound which can induce oxidative stress.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to nucleus during cellular response to oxidative stress","termid":"FYPO:0001789"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000257","FYPO:0001312","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"normal protein localization to nucleus during cellular response to DEM","synonyms":[{"name":"normal protein localisation to nucleus during cellular response to DEM","type":"exact"},{"name":"normal protein localization to nucleus during cellular response to DEM during mitotic cell cycle","type":"related"},{"name":"normal protein localization to nucleus during cellular response to DEM during vegetative growth","type":"exact"},{"name":"normal protein localization to nucleus during cellular response to diethyl maleate","type":"exact"}],"termid":"FYPO:0002145"}


id: MOD:00537
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-threonine residue to L-alanine.","definition_xrefs":["Unimod:659"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-alanine residue","termid":"MOD:00010"},{"relation_name":"is_a","term_name":"modified L-threonine residue","termid":"MOD:00917"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-alanine residue (Thr)","synonyms":[{"name":"Thr(Ala)","type":"exact"},{"name":"Thr->Ala","type":"related"},{"name":"Thr->Ala substitution","type":"related"}],"termid":"MOD:00537"}


id: PBO:0031179
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-mitotic_catastrophe","termid":"PBO:0031179"}


id: MONDO:0012618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0006025","MONDO:0005066"],"is_obsolete":false,"name":"intellectual disability, autosomal recessive 10","secondary_identifiers":["MEDGEN:410010","UMLS:C1970194","OMIM:611096","MESH:C567013","DOID:0081185","GARD:22545"],"synonyms":[{"name":"MRT10","type":"exact"},{"name":"intellectual disability, autosomal recessive 10","type":"exact"},{"name":"intellectual disability, autosomal recessive 20","type":"related"},{"name":"mental retardation, autosomal recessive 10","type":"related"},{"name":"mental retardation, autosomal recessive 10/20","type":"exact"},{"name":"mental retardation, autosomal recessive 20","type":"related"}],"termid":"MONDO:0012618","xrefs":{"Monarch":{"xref_id":"0012618"}}}


id: FYPO:0002861
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of polynucleotide uridylyltransferase (poly(U) polymerase) activity is decreased.","definition_xrefs":["PomBase:mah","PMID:17449726"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal poly(U) polymerase activity","termid":"FYPO:0002860"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0000654","FYPO:0000652","FYPO:0001985","FYPO:0000661"],"is_obsolete":false,"name":"decreased poly(U) polymerase activity","synonyms":[{"name":"decreased RNA uridylyltransferase activity","type":"exact"},{"name":"decreased polynucleotide uridylyltransferase activity","type":"exact"},{"name":"reduced poly(U) polymerase activity","type":"exact"}],"termid":"FYPO:0002861"}


id: PBO:0017434
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-starts_during","termid":"PBO:0017434"}


id: GO:0015843
data:
  {"annotated_genes":["SJAG_04731"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[99576],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072489"}]},"cv_name":"biological_process","definition":"The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic cation transport","termid":"GO:0015695"},{"relation_name":"is_a","term_name":"amine transport","termid":"GO:0015837"},{"relation_name":"is_a","term_name":"one-carbon compound transport","termid":"GO:0019755"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04731":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0008150"],"is_obsolete":false,"name":"methylammonium transport","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0015843","terms_by_termid":{"GO:0072489":null}}


id: PBO:0044027
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CS pseudogene 1","termid":"PBO:0044027"}


id: MONDO:0850812
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A primary immunodeficiency disease characterized by impaired function or reduced numbers of dendritic cells.","definition_xrefs":["DOID:0111963"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn error of immunity","termid":"MONDO:0003778"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"dendritic cell deficiency","secondary_identifiers":["MEDGEN:1656300","UMLS:C4746814"],"termid":"MONDO:0850812","xrefs":{"Monarch":{"xref_id":"0850812"}}}


id: GO:0030781
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.","definition_xrefs":["EC:2.1.1.121"],"direct_ancestors":[{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0003674","GO:0016741"],"is_obsolete":false,"name":"6-O-methylnorlaudanosoline 5'-O-methyltransferase activity","secondary_identifiers":["RHEA:11892","MetaCyc:2.1.1.121-RXN"],"synonyms":[{"name":"S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity","type":"related"}],"termid":"GO:0030781"}


id: PBO:0069840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1126, pseudogene","termid":"PBO:0069840"}


id: GO:0003783
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete barbed-end actin capping activity (obsolete GO:0003783)","synonyms":[{"name":"barbed-end actin capping activity","type":"exact"}],"termid":"GO:0003783"}


id: PBO:0091034
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Swr1 complex histone chaperone module subunit Vps71","termid":"PBO:0091034"}


id: PATO:0000922
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000922 absolute width (obsolete PATO:0000922)","termid":"PATO:0000922"}


id: PBO:0043806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytoplasmic mesoderm regulator","termid":"PBO:0043806"}


id: GO:0000756
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.","definition_xrefs":["GOC:clt"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell communication","termid":"GO:0007154"},{"relation_name":"is_a","term_name":"cellular response to pheromone","termid":"GO:0071444"},{"relation_name":"regulates","term_name":"conjugation with mutual genetic exchange","termid":"GO:0000748"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to pheromone regulating conjugation with mutual genetic exchange","synonyms":[{"name":"response to pheromone triggering conjugation without cellular fusion","type":"exact"}],"termid":"GO:0000756"}


id: PBO:0076344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptotagmin 11","termid":"PBO:0076344"}


id: FYPO:0001984
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is too low to detect. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"substance absent from cell during vegetative growth","termid":"FYPO:0001208"},{"relation_name":"is_a","term_name":"decreased protein level during vegetative growth","termid":"FYPO:0001324"},{"relation_name":"is_a","term_name":"protein absent from cell","termid":"FYPO:0001983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0006551","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"protein absent from cell during vegetative growth","synonyms":[{"name":"protein absent from cell during mitotic cell cycle","type":"related"},{"name":"undetectable cellular protein level during vegetative growth","type":"exact"}],"termid":"FYPO:0001984"}


id: GO:0060211
data:
  {"annotated_genes":["SJAG_04682","SJAG_00686","SJAG_04427","SJAG_01436","SJAG_02370"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[98835],"is_not":false,"summary":null,"term":"GO:0060211"},{"annotations":[92010],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0060212"},{"annotations":[105235,73142,90039],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0060213"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mRNA catabolic process","termid":"GO:0061013"},{"relation_name":"regulates","term_name":"nuclear-transcribed mRNA poly(A) tail shortening","termid":"GO:0000289"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00686":null,"SJAG_01436":null,"SJAG_02370":null,"SJAG_04427":null,"SJAG_04682":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0016071"}],"interesting_parent_ids":["GO:0016071","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of nuclear-transcribed mRNA poly(A) tail shortening","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"regulation of 3' to 5' mRNA deadenylation","type":"related"},{"name":"regulation of mRNA deadenylation","type":"related"},{"name":"regulation of nuclear mRNA poly(A) tail shortening","type":"related"}],"termid":"GO:0060211","terms_by_termid":{"GO:0060211":null,"GO:0060212":null,"GO:0060213":null}}


id: FYPO:0004201
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are present at lower levels than normal.","definition_xrefs":["PomBase:mah","PMID:20211136"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased centromeric outer repeat transcript level","termid":"FYPO:0003094"},{"relation_name":"is_a","term_name":"decreased siRNA level","termid":"FYPO:0004205"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0006551","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"decreased centromeric outer repeat transcript-derived siRNA level","synonyms":[{"name":"decreased accumulation of centromeric outer repeat transcript-derived siRNA","type":"exact"},{"name":"decreased accumulation of siRNAs homologous to outer repeats","type":"related"},{"name":"decreased centromere outer repeat transcript-derived siRNA level","type":"exact"},{"name":"decreased centromeric outer repeat transcript-derived siRNA level during mitotic cell cycle","type":"related"},{"name":"decreased centromeric outer repeat transcript-derived siRNA level during vegetative growth","type":"exact"},{"name":"decreased level of centromeric outer repeat transcript-derived siRNA","type":"exact"},{"name":"decreased level of siRNAs homologous to outer repeats","type":"exact"},{"name":"reduced centromeric outer repeat transcript-derived siRNA level","type":"exact"}],"termid":"FYPO:0004201"}


id: PR:P41412
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- res2 gene.","definition_xrefs":["UniProtKB:P41412","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell division cycle-related protein res2/pct1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22F3.09c","synonyms":[{"name":"Spom972h-res2","type":"exact"}],"termid":"PR:P41412"}


id: PBO:0043534
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"component of oligomeric golgi complex 2","termid":"PBO:0043534"}


id: GO:0070878
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.","definition_xrefs":["PMID:15531877","PMID:15574589","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA binding","termid":"GO:0003723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003723"}],"interesting_parent_ids":["GO:0003723","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"primary miRNA binding","synonyms":[{"name":"pri-miRNA binding","type":"exact"},{"name":"primary microRNA binding","type":"exact"}],"termid":"GO:0070878"}


id: GO:0010087
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.","definition_xrefs":["GOC:mtg_sensu","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tissue development","termid":"GO:0009888"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"phloem or xylem histogenesis","synonyms":[{"name":"vascular tissue development","type":"broad"},{"name":"vascular tissue histogenesis","type":"exact"}],"termid":"GO:0010087"}


id: PBO:0082478
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Carbonic anhydrase; metalloenzyme that catalyzes CO2 hydration to bicarbonate, which is an important metabolic substrate, and protons; not expressed under conditions of high CO2, such as inside a growing colony, but transcription is induced in response to low CO2 levels, such as on the colony surface in ambient air; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; abundance increases in response to DNA replication stress","termid":"PBO:0082478"}


id: PBO:0031153
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_myo-inositol_import","termid":"PBO:0031153"}


id: PBO:0008804
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial Membrane Bound O-Acyl Transferase (MBOAT) family","termid":"PBO:0008804"}


id: GO:0006288
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair.","definition_xrefs":["ISBN:1550091131"],"gene_count":0,"genotype_count":0,"name":"obsolete base-excision repair, DNA ligation (obsolete GO:0006288)","termid":"GO:0006288"}


id: PBO:0073058
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SDAD1 antisense RNA 1","termid":"PBO:0073058"}


id: PBO:0053755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 996","termid":"PBO:0053755"}


id: PBO:0067067
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 93, pseudogene","termid":"PBO:0067067"}


id: PBO:0042793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centrosomal protein 170 pseudogene 1","termid":"PBO:0042793"}


id: PR:Q09830
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC4G8.04 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09830"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TBC domain-containing protein C4G8.04 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4G8.04","synonyms":[{"name":"Spom972h-SPAC4G8.04","type":"exact"}],"termid":"PR:Q09830"}


id: GO:0036046
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.","definition_xrefs":["GOC:sp","PMID:22076378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein deacylation","termid":"GO:0035601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein demalonylation","termid":"GO:0036046"}


id: PBO:0085007
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Negative regulator of the glucose-sensing signal transduction pathway; required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation; MTH1 has a paralog, STD1, that arose from the whole genome duplication","termid":"PBO:0085007"}


id: PBO:0109912
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ferritin heavy chain 1 pseudogene 29","termid":"PBO:0109912"}


id: GO:1905265
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of blasticidin S.","definition_xrefs":["GOC:TermGenie","PMID:23874663","GOC:pr","Wikipedia:Blasticidin_S","GO_REF:0000068"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine nucleoside catabolic process","termid":"GO:0046135"},{"relation_name":"is_a","term_name":"blasticidin S metabolic process","termid":"GO:1905264"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0055086","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"blasticidin S catabolic process","synonyms":[{"name":"blasticidin S breakdown","type":"exact"},{"name":"blasticidin S catabolism","type":"exact"},{"name":"blasticidin S degradation","type":"exact"}],"termid":"GO:1905265"}


id: FYPO:0008327
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in one or more heterochromatin islands occurs to a greater extent than normal.","direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone H3-K9 trimethylation during vegetative growth","termid":"FYPO:0000879"},{"relation_name":"is_a","term_name":"increased histone H3-K9 methylation at heterochromatin island during vegetative growth","termid":"FYPO:0003746"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0002494","FYPO:0005447","FYPO:0002274","FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased histone H3-K9 trimethylation at heterochromatin island during vegetative growth","termid":"FYPO:0008327"}


id: GO:0071741
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.","definition_xrefs":["ISBN:0781765196","GOC:add","PMID:11282392"],"direct_ancestors":[{"relation_name":"is_a","term_name":"IgD immunoglobulin complex","termid":"GO:0071738"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"IgD immunoglobulin complex, GPI-anchored","synonyms":[{"name":"GPI-anchored IgD","type":"exact"}],"termid":"GO:0071741"}


id: PR:O94706
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A transcription initiation factor TFIID subunit 8 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR23307:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription initiation factor TFIID subunit 8 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1259.06","secondary_identifiers":["UniProtKB:O94706"],"synonyms":[{"name":"SPCC1259.06","type":"related"},{"name":"Spom972h-TAF8","type":"exact"},{"name":"TBP-associated factor 8 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94706"}


id: GO:0090688
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The part of the cleavage furrow closest to the cell surface.","definition_xrefs":["GOC:vw","PMID:27082518"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cleavage furrow","termid":"GO:0032154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"cleavage furrow rim","termid":"GO:0090688"}


id: PBO:0071720
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L39 pseudogene 18","termid":"PBO:0071720"}


id: FYPO:0006423
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which cohesion between sister chromatids is decreased in centromeric regions during the first meiotic nuclear division.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased meiotic sister chromatid cohesion at centromere","termid":"FYPO:0005579"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000641"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0000631","FYPO:0001985","FYPO:0000641"],"is_obsolete":false,"name":"decreased meiotic sister chromatid cohesion at centromere during meiosis I","synonyms":[{"name":"decreased meiotic sister chromatid cohesion at centromere during first meiotic nuclear division","type":"exact"},{"name":"decreased meiotic sister chromatid cohesion, centromeric, during meiosis I","type":"exact"},{"name":"decreased sister chromatid cohesion at centromere during meiosis I","type":"exact"},{"name":"reduced meiotic sister chromatid cohesion at centromere during meiosis I","type":"exact"}],"termid":"FYPO:0006423"}


id: GO:0097574
data:
  {"annotated_genes":["SJAG_03011","SJAG_02392","SJAG_00030","SJAG_04522","SJAG_04509","SJAG_04947","SJAG_00596","SJAG_00028","SJAG_01925"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[114460,116473,107915,104962,96176,88227,109726],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0097575"},{"annotations":[100410,104841],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1990463"}]},"cv_name":"cellular_component","definition":"The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.","definition_xrefs":["GOC:pr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00028":null,"SJAG_00030":null,"SJAG_00596":null,"SJAG_01925":null,"SJAG_02392":null,"SJAG_03011":null,"SJAG_04509":null,"SJAG_04522":null,"SJAG_04947":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"lateral part of cell","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0097574","terms_by_termid":{"GO:0097575":null,"GO:1990463":null}}


id: GO:0035131
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-embryonic appendage morphogenesis","termid":"GO:0035120"},{"relation_name":"is_a","term_name":"pelvic fin morphogenesis","termid":"GO:0035139"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"post-embryonic pelvic fin morphogenesis","termid":"GO:0035131"}


id: PBO:0051165
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 3-48","termid":"PBO:0051165"}


id: PBO:0090438
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Lsm2-8 complex subunit Lsm6","termid":"PBO:0090438"}


id: PBO:0070867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L14 pseudogene 5","termid":"PBO:0070867"}


id: MONDO:0019050
data:
  {"annotated_genes":["SJAG_04217","SJAG_00235","SJAG_02297","SJAG_00839","SJAG_02796","SJAG_03929"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85598],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010480"},{"annotations":[86536],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013275"},{"annotations":[86343],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009606"},{"annotations":[85892,85891],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009605"},{"annotations":[85954],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009950"}]},"cv_name":"mondo","definition":"An inherited disorder characterized by structural alterations of a globin chain within the hemoglobin molecule.","definition_xrefs":["NCIT:C3092"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"familial hemolytic anemia","termid":"MONDO:0003689"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"hemoglobinopathy","termid":"MONDO:0044348"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00235":null,"SJAG_00839":null,"SJAG_02297":null,"SJAG_02796":null,"SJAG_03929":null,"SJAG_04217":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"inherited hemoglobinopathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:427306008","MedDRA:10060892","ICD9:282.7","ICD10CM:D58.1","ICD10CM:D58.0","DOID:2860","GARD:18883","MESH:D006453","Orphanet:68364"],"synonyms":[{"name":"Hemoglobinopathies / iron metabolism","type":"exact"},{"name":"hemoglobinopathies","type":"exact"},{"name":"hemoglobinopathy","type":"related"},{"name":"hereditary hemoglobinopathy","type":"exact"}],"termid":"MONDO:0019050","terms_by_termid":{"MONDO:0009605":null,"MONDO:0009606":null,"MONDO:0009950":null,"MONDO:0010480":null,"MONDO:0013275":null},"xrefs":{"Monarch":{"xref_id":"0019050"}}}


id: PBO:0074529
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small NF90 (ILF3) associated RNA C5","termid":"PBO:0074529"}


id: GO:0035194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.","definition_xrefs":["PMID:11201747","GOC:ems","PMID:15020054","PMID:33184244","PMID:32885814","PMID:11713190","PMID:18771919","PMID:15066275"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-transcriptional gene silencing","termid":"GO:0016441"},{"relation_name":"is_a","term_name":"regulatory ncRNA-mediated gene silencing","termid":"GO:0031047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulatory ncRNA-mediated post-transcriptional gene silencing","secondary_identifiers":["GO:0016246","Reactome:R-HSA-426496","Wikipedia:RNA_interference"],"synonyms":[{"name":"PTGS","type":"broad"},{"name":"RNA interference","type":"broad"},{"name":"RNA-dependent post-transcriptional gene silencing","type":"exact"},{"name":"RNA-mediated post-transcriptional gene silencing","type":"exact"},{"name":"RNA-mediated posttranscriptional gene silencing","type":"exact"},{"name":"RNAi","type":"broad"},{"name":"cosuppression","type":"related"},{"name":"ncRNA-mediated post-transcriptional gene silencing","type":"exact"},{"name":"post-transcriptional gene silencing by RNA","type":"related"},{"name":"posttranscriptional gene silencing by RNA","type":"exact"},{"name":"quelling","type":"related"}],"termid":"GO:0035194"}


id: PBO:0001970
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARP2/3 actin-organizing complex subunit Arc4","termid":"PBO:0001970"}


id: GO:1990745
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A quatrefoil tethering complex required for endocytic recycling.","definition_xrefs":["PMID:25799061"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"recycling endosome","termid":"GO:0055037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005768"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0031410","GO:0005575","GO:0005737","GO:0005768","GO:0032991"],"is_obsolete":false,"name":"EARP complex","termid":"GO:1990745"}


id: PR:Q9Y7R6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- big1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9Y7R6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein big1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC306.06c","synonyms":[{"name":"Spom972h-big1","type":"exact"}],"termid":"PR:Q9Y7R6"}


id: GO:0006334
data:
  {"annotated_genes":["SJAG_02906","SJAG_02198","SJAG_00303","SJAG_02314","SJAG_03542","SJAG_04272","SJAG_00942","SJAG_00336","SJAG_04257"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70228,73422,73565,79189,91454,91455,96779,108040,114846],"is_not":false,"summary":null,"term":"GO:0006334"}]},"cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleosome organization","termid":"GO:0034728"},{"relation_name":"is_a","term_name":"protein-DNA complex assembly","termid":"GO:0065004"},{"relation_name":"part_of","term_name":"chromatin organization","termid":"GO:0006325"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00303":null,"SJAG_00336":null,"SJAG_00942":null,"SJAG_02198":null,"SJAG_02314":null,"SJAG_02906":null,"SJAG_03542":null,"SJAG_04257":null,"SJAG_04272":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0006325"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006325"}],"interesting_parent_ids":["GO:0065003","GO:0008150","GO:0044085","GO:0006325"],"is_obsolete":false,"name":"nucleosome assembly","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-774815"],"synonyms":[{"name":"histone chaperone","type":"related"},{"name":"nucleosome modeling","type":"exact"}],"termid":"GO:0006334","terms_by_termid":{"GO:0006334":null}}


id: PBO:0067274
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 352, pseudogene","termid":"PBO:0067274"}


id: GO:0052915
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.","definition_xrefs":["EC:2.1.1.173"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA (guanine-N2-)-methyltransferase activity","termid":"GO:0008990"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0140098","GO:0016741","GO:0003824","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"23S rRNA (guanine(2445)-N(2))-methyltransferase activity","secondary_identifiers":["RHEA:42740","MetaCyc:RXN-11574"],"termid":"GO:0052915"}


id: PBO:0051447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable 4-3","termid":"PBO:0051447"}


id: PBO:0081434
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 285D, pseudogene","termid":"PBO:0081434"}


id: GO:0001575
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycosphingolipid metabolic process","termid":"GO:0006687"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"globoside metabolic process","synonyms":[{"name":"globoside metabolism","type":"exact"}],"termid":"GO:0001575"}


id: PBO:0117101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BCAT1 divergent transcript","termid":"PBO:0117101"}


id: PBO:0051782
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IQ motif containing E","termid":"PBO:0051782"}


id: GO:0036334
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.","definition_xrefs":["PMID:17666529","CL:1000428","GOC:nhn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"homeostasis of number of cells","termid":"GO:0048872"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"epidermal stem cell homeostasis","termid":"GO:0036334"}


id: MONDO:0019222
data:
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id: GO:0140233
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id: GO:0032224
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id: PBO:0044810
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id: MONDO:0850074
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id: PBO:0049184
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"grainyhead like transcription factor 1","termid":"PBO:0049184"}


id: PBO:0012233
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id: PBO:0012256
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  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae TRK1 and TRK2","termid":"PBO:0012256"}


id: MONDO:0007209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Weismann-Netter syndrome is a rare, genetic, primary, bent bone dysplasia characterized by anterior diaphyseal bowing of the tibia and fibula, broadening of the fibula, posterior cortical thickening of both bones and short stature. Additional skeletal abnormalities include scoliosis with marked lumbar lordosis, horizontal sacrum and square iliac wings and/or, less frequently, vertebral malformations, abnormal shape of the clavicles and ribs, calvarial hyperostosis and delayed eruption of permanent teeth. Delayed ambulation is also frequently associated.","definition_xrefs":["Orphanet:3344"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bent bone dysplasia","termid":"MONDO:0019698"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Weismann-Netter syndrome","secondary_identifiers":["GARD:5232","OMIM:112350","UMLS:C1862172","MEDGEN:350610","NORD:1843","icd11.foundation:180927608","SCTID:715532007","MESH:C537082"],"synonyms":[{"name":"Toxopachyosteose Diaphysaire Tibio-Peroniere","type":"related"},{"name":"WEISMANN-NETTER syndrome","type":"exact"},{"name":"WNS","type":"exact"},{"name":"Weismann Netter Stuhl Syndrome","type":"exact"},{"name":"Weismann Netter syndrome","type":"exact"},{"name":"Weismann-Netter syndrome","type":"exact"},{"name":"Weismann-Netter-Stuhl syndrome","type":"exact"},{"name":"anterior bowing of legs with dwarfism","type":"exact"},{"name":"bowing of legs, anterior with dwarfism","type":"related"},{"name":"bowing of legs, anterior, with dwarfism","type":"related"}],"termid":"MONDO:0007209","xrefs":{"Monarch":{"xref_id":"0007209"}}}


id: PBO:0056980
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 29c","termid":"PBO:0056980"}


id: MONDO:0008541
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id: GO:0005743
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