# terms

id: GO:0015716
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inorganic anion transport","termid":"GO:0015698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"organic phosphonate transport","secondary_identifiers":["GO:0042916"],"synonyms":[{"name":"alkylphosphonate transport","type":"narrow"}],"termid":"GO:0015716"}


id: GO:0007018
data:
  {"annotated_genes":["SJAG_00332","SJAG_00773","SJAG_01662","SJAG_03835","SJAG_00140","SJAG_04001","SJAG_00851","SJAG_02624","SJAG_03540","SJAG_03673","SJAG_04076","SJAG_04884","SJAG_01224","SJAG_04143","SJAG_05185","SJAG_00042","SJAG_00930","SJAG_02045","SJAG_02848","SJAG_02761","SJAG_01613","SJAG_03683","SJAG_01371","SJAG_03073","SJAG_01370","SJAG_01211","SJAG_01775","SJAG_02286","SJAG_01297","SJAG_02731","SJAG_05266","SJAG_01805","SJAG_00397","SJAG_01863","SJAG_04745","SJAG_02737","SJAG_02431","SJAG_04597","SJAG_02561","SJAG_00113","SJAG_00368","SJAG_00794","SJAG_02336","SJAG_00918","SJAG_05220","SJAG_05319","SJAG_01546","SJAG_00594","SJAG_04387","SJAG_04003","SJAG_02814","SJAG_03437","SJAG_02651","SJAG_02509"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[61461,64270,74189],"is_not":false,"summary":null,"term":"GO:0007018"},{"annotations":[91334,111710,95543,117243,103279,111361,103571,88098,92183,114252,101048,91725,97902],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030989"},{"annotations":[103077],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034643"},{"annotations":[101750,106905,111534],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0032118"},{"annotations":[102750,100701,94138,99545,95647,118963,118449,116226,109450],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990571"},{"annotations":[95110,110212],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0099606"},{"annotations":[99551],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031534"},{"annotations":[104210,100703,108567],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007079"},{"annotations":[101760],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0062168"},{"annotations":[71024,101761,75473,107740,109917,114254,117247],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098863"},{"annotations":[97977,99557],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090561"},{"annotations":[97904,88102,76700,91727,99558],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000743"},{"annotations":[99559],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031535"},{"annotations":[94752],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1902854"},{"annotations":[104063],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0099117"},{"annotations":[100707,108576,118967,104218],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140210"},{"annotations":[98950,91322,107816,114403,109196,110199,97105,90088,117217,89484,100843],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990976"},{"annotations":[117248],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140405"},{"annotations":[91491],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010970"},{"annotations":[104861,105192],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0047496"}]},"cv_name":"biological_process","definition":"A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.","definition_xrefs":["ISBN:0815316194","GOC:cjm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule-based process","termid":"GO:0007017"}],"gene_count":54,"genes_by_uniquename":{"SJAG_00042":null,"SJAG_00113":null,"SJAG_00140":null,"SJAG_00332":null,"SJAG_00368":null,"SJAG_00397":null,"SJAG_00594":null,"SJAG_00773":null,"SJAG_00794":null,"SJAG_00851":null,"SJAG_00918":null,"SJAG_00930":null,"SJAG_01211":null,"SJAG_01224":null,"SJAG_01297":null,"SJAG_01370":null,"SJAG_01371":null,"SJAG_01546":null,"SJAG_01613":null,"SJAG_01662":null,"SJAG_01775":null,"SJAG_01805":null,"SJAG_01863":null,"SJAG_02045":null,"SJAG_02286":null,"SJAG_02336":null,"SJAG_02431":null,"SJAG_02509":null,"SJAG_02561":null,"SJAG_02624":null,"SJAG_02651":null,"SJAG_02731":null,"SJAG_02737":null,"SJAG_02761":null,"SJAG_02814":null,"SJAG_02848":null,"SJAG_03073":null,"SJAG_03437":null,"SJAG_03540":null,"SJAG_03673":null,"SJAG_03683":null,"SJAG_03835":null,"SJAG_04001":null,"SJAG_04003":null,"SJAG_04076":null,"SJAG_04143":null,"SJAG_04387":null,"SJAG_04597":null,"SJAG_04745":null,"SJAG_04884":null,"SJAG_05185":null,"SJAG_05220":null,"SJAG_05266":null,"SJAG_05319":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"microtubule-based movement","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-983189"],"termid":"GO:0007018","terms_by_termid":{"GO:0000743":null,"GO:0007018":null,"GO:0007079":null,"GO:0010970":null,"GO:0030989":null,"GO:0031534":null,"GO:0031535":null,"GO:0032118":null,"GO:0034643":null,"GO:0047496":null,"GO:0062168":null,"GO:0090561":null,"GO:0098863":null,"GO:0099117":null,"GO:0099606":null,"GO:0140210":null,"GO:0140405":null,"GO:1902854":null,"GO:1990571":null,"GO:1990976":null}}


id: FYPO:0001653
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the import of lysine into the cell is abnormal in the vegetative growth phase of the life cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal amino acid import during vegetative growth","termid":"FYPO:0001361"},{"relation_name":"is_a","term_name":"abnormal lysine import","termid":"FYPO:0001651"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0000138","FYPO:0001320"],"is_obsolete":false,"name":"abnormal lysine import during vegetative growth","synonyms":[{"name":"abnormal L-lysine import across plasma membrane during vegetative growth","type":"exact"},{"name":"abnormal L-lysine import during vegetative growth","type":"exact"},{"name":"abnormal lysine import during mitotic cell cycle","type":"related"},{"name":"abnormal lysine import into cell during vegetative growth","type":"exact"},{"name":"abnormal lysine uptake during vegetative growth","type":"exact"}],"termid":"FYPO:0001653"}


id: GO:0071267
data:
  {"annotated_genes":["SJAG_00309","SJAG_02689","SJAG_03614","SJAG_03881","SJAG_01404","SJAG_02293"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79583,78220,77263,78671,58760,80460],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019509"}]},"cv_name":"biological_process","definition":"Any process that generates L-methionine from derivatives of it, without de novo synthesis.","definition_xrefs":["GOC:ecd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid salvage","termid":"GO:0043102"},{"relation_name":"is_a","term_name":"L-methionine biosynthetic process","termid":"GO:0071265"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00309":null,"SJAG_01404":null,"SJAG_02293":null,"SJAG_02689":null,"SJAG_03614":null,"SJAG_03881":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0006790","GO:0044281","GO:0006520","GO:0008150"],"is_obsolete":false,"name":"L-methionine salvage","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null},"termid":"GO:0071267","terms_by_termid":{"GO:0019509":null}}


id: PBO:0068828
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 66, pseudogene","termid":"PBO:0068828"}


id: PBO:0031837
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_mitochondrial_morphology","termid":"PBO:0031837"}


id: GO:0061989
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.","definition_xrefs":["PMID:19696886"],"direct_ancestors":[{"relation_name":"is_a","term_name":"karyosome formation","termid":"GO:0061988"},{"relation_name":"part_of","term_name":"spermatogenesis","termid":"GO:0007283"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007049","GO:0008150"],"is_obsolete":false,"name":"sperm karyosome formation","termid":"GO:0061989"}


id: GO:0106300
data:
  {"annotated_genes":["SJAG_00406","SJAG_02223"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[98631,106412],"is_not":false,"summary":null,"term":"GO:0106300"}]},"cv_name":"biological_process","definition":"The removal of covalent cross-link between DNA and a protein.","definition_xrefs":["PMID:31921408"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA repair","termid":"GO:0006281"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00406":null,"SJAG_02223":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0006281"],"is_obsolete":false,"name":"protein-DNA covalent cross-linking repair","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"resolution of protein-DNA covalent cross-linking","type":"exact"}],"termid":"GO:0106300","terms_by_termid":{"GO:0106300":null}}


id: MONDO:0015248
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic, multiple congenital anomalies/dysmorphic syndrome characterized by cerebellar-like ataxia, photosensitivity (mainly of the face and trunk), short stature and intellectual disability. Additional features include clinodactyly, single palmar transverse crease, high-arched palate, pseudohypertrophy of the calves and aortic valve lesions. There have been no further descriptions in the literature since 1983.","definition_xrefs":["Orphanet:1184"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary ataxia","termid":"MONDO:0100309"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ataxia-photosensitivity-short stature syndrome","secondary_identifiers":["GARD:2287","MEDGEN:1655873","UMLS:C4751230"],"synonyms":[{"name":"Fenton Wilkinson Toselano syndrome","type":"exact"},{"name":"Fenton-Wilkinson-Toselano syndrome","type":"exact"}],"termid":"MONDO:0015248","xrefs":{"Monarch":{"xref_id":"0015248"}}}


id: MONDO:0010291
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete androgen insensitivity syndrome due to coactivator deficiency (obsolete MONDO:0010291)","secondary_identifiers":["OMIM:300274"],"synonyms":[{"name":"androgen insensitivity syndrome due to coactivator deficiency","type":"related"}],"termid":"MONDO:0010291","xrefs":{"Monarch":{"xref_id":"0010291"}}}


id: FYECO:0000458
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Cells were subjected to nitrogen starvation for 14 days.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping starvation and timing","termid":"FYECO:0000239"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"14 days nitrogen starvation","termid":"FYECO:0000458"}


id: PBO:0054109
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1474","termid":"PBO:0054109"}


id: PBO:0055916
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 37 member A4, pseudogene","termid":"PBO:0055916"}


id: GO:0089700
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound.","definition_xrefs":["GOC:BHF","GOC:mah","GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete protein kinase D signaling (obsolete GO:0089700)","synonyms":[{"name":"PKD signal transduction","type":"exact"},{"name":"PKD signaling cascade","type":"related"},{"name":"protein kinase D signal transduction","type":"exact"},{"name":"protein kinase D signaling cascade","type":"related"},{"name":"protein kinase D signalling cascade","type":"related"}],"termid":"GO:0089700"}


id: GO:0097438
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.","definition_xrefs":["PO_REF:00009","GOC:PO_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dormancy process","termid":"GO:0022611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"exit from dormancy","synonyms":[{"name":"release from dormancy","type":"exact"}],"termid":"GO:0097438"}


id: MONDO:0012061
data:
  {"annotated_genes":["SJAG_03081"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86711],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0859173"}]},"cv_name":"mondo","definition":"Sick sinus syndrome is a rare cardiac rhythm disease, usually of the elderly, characterized by electrocardiographic findings of sinus bradycardia, atrial fibrillation, atrial tachycardia sinus arrest, or sino-atrial block, and that manifest with symptoms like syncope, dizziness, palpitations, fatigue, or even heart failure. It results from malfunction of the cardiac conduction system, probably secondary to degenerative fibrosis of nodal tissue in the elderly or secondary to cardiac disorders in younger patients.","definition_xrefs":["Orphanet:166282"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sick sinus syndrome","termid":"MONDO:0001823"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03081":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"familial sick sinus syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:573766","SCTID:233913007","icd11.foundation:1495462959","GARD:13663","MedDRA:10040639","MESH:C563907","UMLS:C0340491","OMIMPS:608567"],"synonyms":[{"name":"SSS1","type":"related"},{"name":"familial sinus node dysfunction","type":"exact"},{"name":"hereditary sick sinus syndrome","type":"exact"},{"name":"sick sinus syndrome 1, autosomal recessive","type":"related"}],"termid":"MONDO:0012061","terms_by_termid":{"MONDO:0859173":null},"xrefs":{"Monarch":{"xref_id":"0012061"}}}


id: GO:0034000
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.","definition_xrefs":["EC:4.2.2.20"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-oxygen lyase activity, acting on polysaccharides","termid":"GO:0016837"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"chondroitin-sulfate-ABC endolyase activity","synonyms":[{"name":"ChS ABC lyase I activity","type":"related"},{"name":"ChS ABC lyase activity","type":"broad"},{"name":"chondroitin ABC eliminase activity","type":"broad"},{"name":"chondroitin sulfate ABC endoeliminase activity","type":"related"},{"name":"chondroitin sulfate ABC endolyase activity","type":"related"},{"name":"chondroitin sulfate ABC lyase activity","type":"broad"},{"name":"chondroitinase ABC activity","type":"broad"},{"name":"chondroitinase activity","type":"broad"}],"termid":"GO:0034000"}


id: MONDO:0006742
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Thyroid gland enlargement caused by inadequate dietary iodine intake. It occurs in areas in which the soil lacks iodine compounds or there is low seafood consumption.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"goiter","termid":"MONDO:0005397"},{"relation_name":"is_a","term_name":"nutritional deficiency disease","termid":"MONDO:0006873"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endemic goiter","secondary_identifiers":["SCTID:56805008","SCTID:267369002","MedDRA:10068848","EFO:1000916","MEDGEN:5357","UMLS:C0018022","DOID:13198","ICD9:240.0","MESH:D006043","NCIT:C35023"],"synonyms":[{"name":"iodine-deficiency-related endemic goiter","type":"exact"},{"name":"iodine-deficiency-related endemic goitre","type":"exact"},{"name":"simple goiter","type":"exact"},{"name":"simple goitre","type":"exact"}],"termid":"MONDO:0006742","xrefs":{"Monarch":{"xref_id":"0006742"}}}


id: MONDO:0012560
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete invasive pneumococcal disease, recurrent isolated, 1 (obsolete MONDO:0012560)","secondary_identifiers":["OMIM:610799"],"termid":"MONDO:0012560","xrefs":{"Monarch":{"xref_id":"0012560"}}}


id: MONDO:0009002
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"coloboma","termid":"MONDO:0001476"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"coloboma, ocular, autosomal recessive","secondary_identifiers":["OMIM:216820","UMLS:C4011974","MEDGEN:860411"],"synonyms":[{"name":"coloboma, ocular, autosomal recessive","type":"exact"}],"termid":"MONDO:0009002","xrefs":{"Monarch":{"xref_id":"0009002"}}}


id: GO:0035752
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.","definition_xrefs":["GOC:bf","GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of lysosomal lumen pH","termid":"GO:0035751"},{"relation_name":"is_a","term_name":"intracellular pH elevation","termid":"GO:0051454"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lysosomal lumen pH elevation","synonyms":[{"name":"lysosome pH elevation","type":"exact"}],"termid":"GO:0035752"}


id: MONDO:0008858
data:
  {"annotated_genes":["SJAG_02656"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86243],"is_not":false,"summary":null,"term":"MONDO:0008858"}]},"cv_name":"mondo","definition":"A disorder characterized by early-onset optic atrophy along with neurological features, including ataxia, spasticity, and intellectual disability. Other signs and symptoms may be present and vary from person to person. This condition is caused by mutations in the OPA1 gene. It is inherited in an autosomal recessive manner. Treatment depends on the specific signs and symptoms seen in the patient.","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"},{"relation_name":"is_a","term_name":"OPA1-related optic atrophy with or without extraocular features","termid":"MONDO:0800181"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02656":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0006025","MONDO:0005328","MONDO:0004069"],"is_obsolete":false,"name":"Behr syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:210000","MESH:C537669","DOID:0111580","ICD10CM:H35.5","GARD:849","MEDGEN:66358","SCTID:718221007","UMLS:C0221061","NCIT:C177251","Orphanet:1239"],"synonyms":[{"name":"BEHRS","type":"related"},{"name":"Behr syndrome","type":"exact"},{"name":"optic atrophy in early childhood, associated with ataxia, spasticity, intellectual disability, and posterior column sensory loss","type":"related"},{"name":"optic atrophy in early childhood, associated with ataxia, spasticity, mental retardation, and posterior column sensory loss","type":"related"},{"name":"optic atrophy, infantile hereditary, Behr complicated form of","type":"related"},{"name":"optic atrophy, infantile hereditary, with neurologic abnormalities","type":"related"}],"termid":"MONDO:0008858","terms_by_termid":{"MONDO:0008858":null},"xrefs":{"Monarch":{"xref_id":"0008858"}}}


id: PBO:0046671
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"estrogen related receptor beta","termid":"PBO:0046671"}


id: GO:0098844
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta.","definition_xrefs":["PMID:17880892"],"direct_ancestors":[{"relation_name":"is_a","term_name":"synaptic membrane","termid":"GO:0097060"},{"relation_name":"part_of","term_name":"postsynaptic membrane","termid":"GO:0045211"},{"relation_name":"part_of","term_name":"postsynaptic endocytic zone","termid":"GO:0098843"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005886"],"is_obsolete":false,"name":"postsynaptic endocytic zone membrane","termid":"GO:0098844"}


id: PBO:0003287
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HIRA interacting protein","termid":"PBO:0003287"}


id: GO:0042469
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reduction of versicolorin A to sterigmatocystin.","definition_xrefs":["PMID:1339261"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on CH-OH group of donors","termid":"GO:0016614"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"versicolorin reductase activity","termid":"GO:0042469"}


id: RO:0002263
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"c involved in regulation of p if c enables  'p' and p' causally upstream of p","direct_ancestors":[{"relation_name":"is_a","term_name":"acts_upstream_of_or_within","termid":"RO:0002264"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acts_upstream_of","termid":"RO:0002263"}


id: PBO:0088580
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial carrier, glutamate/glycine","termid":"PBO:0088580"}


id: PBO:0065310
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine protease 30, pseudogene","termid":"PBO:0065310"}


id: PBO:0091015
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RCC domain protein Ats1","termid":"PBO:0091015"}


id: GO:1905695
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.","definition_xrefs":["GOC:PARL","GO_REF:0000058","GOC:TermGenie","PMID:23767959","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of phospholipid biosynthetic process","termid":"GO:0071073"},{"relation_name":"is_a","term_name":"regulation of phosphatidic acid biosynthetic process","termid":"GO:1905693"},{"relation_name":"positively_regulates","term_name":"phosphatidic acid biosynthetic process","termid":"GO:0006654"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"positive regulation of phosphatidic acid biosynthetic process","synonyms":[{"name":"activation of phosphatidic acid anabolism","type":"narrow"},{"name":"activation of phosphatidic acid biosynthesis","type":"narrow"},{"name":"activation of phosphatidic acid biosynthetic process","type":"narrow"},{"name":"activation of phosphatidic acid formation","type":"narrow"},{"name":"activation of phosphatidic acid synthesis","type":"narrow"},{"name":"positive regulation of phosphatidic acid anabolism","type":"exact"},{"name":"positive regulation of phosphatidic acid biosynthesis","type":"exact"},{"name":"positive regulation of phosphatidic acid formation","type":"exact"},{"name":"positive regulation of phosphatidic acid synthesis","type":"exact"},{"name":"up regulation of phosphatidic acid anabolism","type":"exact"},{"name":"up regulation of phosphatidic acid biosynthesis","type":"exact"},{"name":"up regulation of phosphatidic acid biosynthetic process","type":"exact"},{"name":"up regulation of phosphatidic acid formation","type":"exact"},{"name":"up regulation of phosphatidic acid synthesis","type":"exact"},{"name":"up-regulation of phosphatidic acid anabolism","type":"exact"},{"name":"up-regulation of phosphatidic acid biosynthesis","type":"exact"},{"name":"up-regulation of phosphatidic acid biosynthetic process","type":"exact"},{"name":"up-regulation of phosphatidic acid formation","type":"exact"},{"name":"up-regulation of phosphatidic acid synthesis","type":"exact"},{"name":"upregulation of phosphatidic acid anabolism","type":"exact"},{"name":"upregulation of phosphatidic acid biosynthesis","type":"exact"},{"name":"upregulation of phosphatidic acid biosynthetic process","type":"exact"},{"name":"upregulation of phosphatidic acid formation","type":"exact"},{"name":"upregulation of phosphatidic acid synthesis","type":"exact"}],"termid":"GO:1905695"}


id: PR:O94318
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A charged multivesicular body protein 6 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03971"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar protein sorting-associated protein 20 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC215.14c","secondary_identifiers":["UniProtKB:O94318"],"synonyms":[{"name":"Spom972h-CHMP6","type":"exact"}],"termid":"PR:O94318"}


id: PBO:0080601
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WDR35 divergent transcript","termid":"PBO:0080601"}


id: PBO:0067672
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 853, pseudogene","termid":"PBO:0067672"}


id: GO:0006015
data:
  {"annotated_genes":["SJAG_04882","SJAG_04970","SJAG_03811"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[63629,72763,74223],"is_not":false,"summary":null,"term":"GO:0006015"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribose phosphate biosynthetic process","termid":"GO:0046390"},{"relation_name":"is_a","term_name":"5-phosphoribose 1-diphosphate metabolic process","termid":"GO:0046391"}],"gene_count":3,"genes_by_uniquename":{"SJAG_03811":null,"SJAG_04882":null,"SJAG_04970":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"5-phosphoribose 1-diphosphate biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000117":null},"secondary_identifiers":["Reactome:R-HSA-73843"],"synonyms":[{"name":"5-phosphoribose 1-diphosphate anabolism","type":"exact"},{"name":"5-phosphoribose 1-diphosphate biosynthesis","type":"exact"},{"name":"5-phosphoribose 1-diphosphate formation","type":"exact"},{"name":"5-phosphoribose 1-diphosphate synthesis","type":"exact"},{"name":"5-phosphoribosyl-1-pyrophosphate biosynthesis","type":"exact"},{"name":"5-phosphoribosyl-1-pyrophosphate biosynthetic process","type":"exact"},{"name":"PRPP biosynthetic process","type":"exact"}],"termid":"GO:0006015","terms_by_termid":{"GO:0006015":null}}


id: GO:0003031
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.","definition_xrefs":["GOC:mtg_cardio"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of chemical stimulus","termid":"GO:0009593"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of carbon dioxide","termid":"GO:0003031"}


id: MONDO:0015437
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ring chromosome 21 syndrome is an autosomal anomaly characterized by variable clinical features, most commonly including growth retardation, developmental delay, intellectual disability, epilepsy, microcephaly, short stature, dysmorphic features, hypogammaglobulinemia, thrombocytopenia and unspecific skeletal anomalies (hemivertebrae, clinodactyly, syndactyly). In rare cases, it has been described in phenotypically normal individuals.","definition_xrefs":["Orphanet:1445"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ring chromosome disorder","termid":"MONDO:0700091"},{"relation_name":"is_a","term_name":"chromosome 21 disorder","termid":"MONDO:0700124"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring chromosome 21","secondary_identifiers":["SCTID:31325007","UMLS:C2931422","GARD:6083","NORD:947","MEDGEN:419409","MESH:C537109"],"synonyms":[{"name":"Chromosome 21 Ring","type":"exact"},{"name":"R21","type":"related"},{"name":"Ring 21","type":"related"},{"name":"Ring chromosome 21 syndrome","type":"related"},{"name":"Ring chromosome type 21","type":"exact"},{"name":"chromosome 21 en anneau","type":"exact"},{"name":"chromosome 21 ring","type":"related"}],"termid":"MONDO:0015437","xrefs":{"Monarch":{"xref_id":"0015437"}}}


id: PBO:0039496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 20 family member A19, pseudogene","termid":"PBO:0039496"}


id: CHEBI:61049
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tacrolimus (anhydrous)","termid":"CHEBI:61049"}


id: PBO:0016619
data:
  {"annotation_feature_type":"gene","cv_name":"feature_cvtermprop_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"quant_gene_ex_copies_per_cell","termid":"PBO:0016619"}


id: PBO:0063140
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAS domain containing serine/threonine kinase","termid":"PBO:0063140"}


id: PR:O59807
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC550.09 gene.","definition_xrefs":["UniProtKB:O59807","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxisomal membrane protein pex32 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC550.09","synonyms":[{"name":"Spom972h-SPCC550.09","type":"exact"},{"name":"peroxin-32 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O59807"}


id: GO:1905231
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.","definition_xrefs":["GOC:TermGenie","GO_REF:0000071","PMID:26593909"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to lipid","termid":"GO:0071396"},{"relation_name":"is_a","term_name":"response to borneol","termid":"GO:1905230"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to borneol","termid":"GO:1905231"}


id: PBO:0055053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2469","termid":"PBO:0055053"}


id: PBO:0055097
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2515","termid":"PBO:0055097"}


id: PBO:0056165
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAD2L1 binding protein","termid":"PBO:0056165"}


id: MOD:01680
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces one residue alpha amino or imino hydrogen with one methyl group.","definition_xrefs":["OMSSA:76","Unimod:34#N-term","OMSSA:11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monomethylated residue","termid":"MOD:00599"},{"relation_name":"is_a","term_name":"alpha-amino methylated residue","termid":"MOD:01460"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"alpha-amino monomethylated residue","synonyms":[{"name":"Methyl","type":"related"},{"name":"Methylation","type":"related"},{"name":"N2Me1Res","type":"exact"},{"name":"ntermmethyl","type":"exact"},{"name":"ntermpepmethyl","type":"exact"}],"termid":"MOD:01680"}


id: RO:0008506
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"An interaction relationship describing organisms that often occur together at the same time and space or in the same environment.","direct_ancestors":[{"relation_name":"is_a","term_name":"ecologically_related_to","termid":"RO:0002321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"co-occurs","termid":"RO:0008506"}


id: GO:1990330
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consists of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.","definition_xrefs":["GOC:bhm","PMID:20404999"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-cysteine desulfurase complex","termid":"GO:1990221"},{"relation_name":"is_a","term_name":"iron-sulfur cluster assembly complex","termid":"GO:1990229"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005829"}],"interesting_parent_ids":["GO:0032991","GO:0005829","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"IscS-IscU complex","termid":"GO:1990330"}


id: PBO:0043591
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type XXI alpha 1 chain","termid":"PBO:0043591"}


id: PBO:0091193
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Pro","termid":"PBO:0091193"}


id: MONDO:0100151
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive condition caused by mutation(s) in the CTNS gene, encoding cystinosin. It is a sub-type of cystinosis, in which accumulation of cystine in the kidney results in renal dysfunction.","definition_xrefs":["NCIT:C129932"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"cystinosis","termid":"MONDO:0016239"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002561"}],"interesting_parent_ids":["MONDO:0002561","MONDO:0006025","MONDO:0005066"],"is_obsolete":false,"name":"nephropathic cystinosis","secondary_identifiers":["GARD:10074","NANDO:1200162","MESH:C535335","MEDGEN:419735","icd11.foundation:810546659","UMLS:C2931187","NANDO:2201234","OMIM:219800"],"synonyms":[{"name":"Abderhalden Kaufmann Lignac syndrome","type":"exact"},{"name":"Abderhalden Lignac Kaufmann disease","type":"exact"},{"name":"Abderhalden-Kaufmann-Lignac syndrome","type":"exact"},{"name":"Abderhalden-Lignac-Kaufmann disease","type":"exact"},{"name":"CTNS","type":"exact"},{"name":"cystinosis, atypical nephropathic","type":"exact"},{"name":"cystinosis, nephropathic","type":"exact"}],"termid":"MONDO:0100151","xrefs":{"Monarch":{"xref_id":"0100151"}}}


id: GO:0044408
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism.","definition_xrefs":["GOC:cc"],"gene_count":0,"genotype_count":0,"name":"obsolete growth or development of symbiont on or near host (obsolete GO:0044408)","synonyms":[{"name":"growth or development of organism on or near host surface","type":"exact"},{"name":"growth or development of symbiont on or near host","type":"exact"}],"termid":"GO:0044408"}


id: PBO:0088738
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone H3.3-H4 chaperone, HIR complex subunit Hip3","termid":"PBO:0088738"}


id: PBO:0017527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NLI interacting factor family phosphatase Psr1 (predicted)","termid":"PBO:0017527"}


id: PBO:0057249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 450b","termid":"PBO:0057249"}


id: MONDO:0009636
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any mitochondrial DNA depletion syndrome in which the cause of the disease is a mutation in the DGUOK gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of purine metabolism","termid":"MONDO:0019236"},{"relation_name":"is_a","term_name":"mitochondrial DNA depletion syndrome, hepatocerebral form","termid":"MONDO:0100512"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0019254"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069","MONDO:0019254"],"is_obsolete":false,"name":"mitochondrial DNA depletion syndrome 3 (hepatocerebral type)","secondary_identifiers":["GARD:13644","OMIM:251880","UMLS:C5191055","DOID:0080121","MEDGEN:1682503","Orphanet:279934"],"synonyms":[{"name":"DGUOK mitochondrial DNA depletion syndrome","type":"exact"},{"name":"MTDPS3","type":"related"},{"name":"mitochondrial DNA depletion syndrome 3","type":"exact"},{"name":"mitochondrial DNA depletion syndrome 3 (hepatocerebral type)","type":"exact"},{"name":"mitochondrial DNA depletion syndrome caused by mutation in DGUOK","type":"exact"},{"name":"mitochondrial DNA depletion syndrome type 3","type":"exact"},{"name":"mitochondrial DNA depletion syndrome, hepatocerebral form due to DGUOK deficiency","type":"related"}],"termid":"MONDO:0009636","xrefs":{"Monarch":{"xref_id":"0009636"}}}


id: GO:0006306
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.","definition_xrefs":["GOC:ems","ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete DNA methylation (obsolete GO:0006306)","secondary_identifiers":["Wikipedia:DNA_methylation"],"termid":"GO:0006306"}


id: GO:0004989
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled amine receptor activity","termid":"GO:0008227"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"octopamine receptor activity","termid":"GO:0004989"}


id: MONDO:0054782
data:
  {"annotated_genes":["SJAG_03277","SJAG_01259"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86354,86355],"is_not":false,"summary":null,"term":"MONDO:0054782"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"leukodystrophy","termid":"MONDO:0019046"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01259":null,"SJAG_03277":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"leukodystrophy, hypomyelinating, 15","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0070398","MEDGEN:1633653","UMLS:C4693733","OMIM:617951"],"synonyms":[{"name":"HLD15","type":"related"},{"name":"leukodystrophy, hypomyelinating, 15","type":"exact"}],"termid":"MONDO:0054782","terms_by_termid":{"MONDO:0054782":null},"xrefs":{"Monarch":{"xref_id":"0054782"}}}


id: MONDO:0001579
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"corneal disorder","termid":"MONDO:0000942"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"corneal staphyloma","secondary_identifiers":["MEDGEN:509034","icd11.foundation:212928655","DOID:12753","UMLS:C0152440","SCTID:52476003","ICD9:371.73"],"termid":"MONDO:0001579","xrefs":{"Monarch":{"xref_id":"0001579"}}}


id: PBO:0085562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein containing SH3-domains; involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p","termid":"PBO:0085562"}


id: GO:0043472
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an immunoglobulin of a D isotype.","definition_xrefs":["PMID:12886015"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immunoglobulin binding","termid":"GO:0019865"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"IgD binding","termid":"GO:0043472"}


id: MONDO:0100464
data:
  {"annotated_genes":["SJAG_00570"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87270],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009756"},{"annotations":[86554],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011871"}]},"cv_name":"mondo","definition":"An autosomal recessive lysosomal disease caused by biallelic loss of function variants in the SMPD1 gene. Clinical symptoms in affected individuals occur along a continuum. At the severe end of the spectrum are individuals historically diagnosed with Niemann-Pick disease type A (the neurovisceral form), which is characterized by hepatosplenomegaly with rapid neurological deterioration leading to death in the first few years of life. At the milder end of the spectrum are individuals historically diagnosed with Niemann-Pick disease type B, a later-onset, chronic visceral form, characterized by progressive visceral organ symptoms including hepatosplenomegaly and pulmonary insufficiency, and survival into adulthood. In addition, some affected individuals present with an intermediate phenotype, Niemann-Pick disease type A/B.","definition_xrefs":["PMID:34654332","PMID:20301544","PMID:28406489"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Niemann-Pick disease","termid":"MONDO:0001982"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00570":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005046","MONDO:0005066","MONDO:0002561"],"is_obsolete":false,"name":"acid sphingomyelinase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1800807","UMLS:C5243927"],"termid":"MONDO:0100464","terms_by_termid":{"MONDO:0009756":null,"MONDO:0011871":null},"xrefs":{"Monarch":{"xref_id":"0100464"}}}


id: PBO:0017997
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"siderophore-iron transmembrane transporter Str1","termid":"PBO:0017997"}


id: PBO:0004863
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prohibitin (predicted)","termid":"PBO:0004863"}


id: PBO:0043436
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"connector enhancer of kinase suppressor of Ras 2","termid":"PBO:0043436"}


id: PBO:0016043
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by rat PTBP3","termid":"PBO:0016043"}


id: MONDO:0021569
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Emery-Dreifuss muscular dystrophy inherited in an autosomal dominant pattern and caused by mutations in the LMNA gene.","definition_xrefs":["NCIT:C126745"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscular dystrophy, limb-girdle, autosomal dominant","termid":"MONDO:0015151"},{"relation_name":"is_a","term_name":"autosomal dominant Emery-Dreifuss muscular dystrophy","termid":"MONDO:0020336"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0005336","MONDO:0005267"],"is_obsolete":false,"name":"Emery-Dreifuss muscular dystrophy 2, autosomal dominant","secondary_identifiers":["MESH:C535898","Orphanet:264","MEDGEN:98048","SCTID:240072005","SCTID:718178006","OMIM:159001","DOID:0110301","GARD:10230","DOID:0070247","OMIM:181350","UMLS:C0410190","ICD9:425.4"],"synonyms":[{"name":"EDMD2","type":"exact"},{"name":"EMD2","type":"related"},{"name":"Emery-Dreifuss muscular dystrophy 2, autosomal dominant","type":"exact"},{"name":"Emery-Dreifuss muscular dystrophy, autosomal dominant","type":"related"},{"name":"Hauptmann-Thannhauser muscular dystrophy","type":"exact"},{"name":"LGMD1B","type":"exact"},{"name":"LMNA autosomal dominant limb-girdle muscular dystrophy","type":"exact"},{"name":"autosomal dominant limb-girdle muscular dystrophy caused by mutation in LMNA","type":"exact"},{"name":"autosomal dominant limb-girdle muscular dystrophy type 1B","type":"exact"},{"name":"benign scapuloperoneal muscular dystrophy with cardiomyopathy","type":"related"},{"name":"limb-girdle muscular dystrophy due to lamin A/C deficiency","type":"exact"},{"name":"limb-girdle muscular dystrophy type 1B","type":"related"},{"name":"muscular dystrophy with early contractures and cardiomyopathy, autosomal dominant","type":"related"},{"name":"muscular dystrophy, limb-girdle type 1B","type":"exact"},{"name":"muscular dystrophy, limb-girdle, type 1B","type":"related"},{"name":"muscular dystrophy, proximal, type 1B","type":"related"},{"name":"proximal muscular dystrophy type 1B","type":"exact"},{"name":"scapuloilioperoneal atrophy with cardiopathy","type":"related"}],"termid":"MONDO:0021569","xrefs":{"Monarch":{"xref_id":"0021569"}}}


id: PBO:0119276
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial and cytoplasmic cysteine-tRNA ligase Crs1","termid":"PBO:0119276"}


id: GO:0015565
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.","definition_xrefs":["GOC:mtg_transport","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-threonine transmembrane transporter activity","termid":"GO:0015195"},{"relation_name":"is_a","term_name":"L-amino acid efflux transmembrane transporter activity","termid":"GO:0034639"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"threonine efflux transmembrane transporter activity","synonyms":[{"name":"threonine efflux permease activity","type":"exact"},{"name":"threonine export protein","type":"related"},{"name":"threonine export transporter activity","type":"exact"}],"termid":"GO:0015565"}


id: PBO:0079447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TUB like protein 4","termid":"PBO:0079447"}


id: MONDO:0004831
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rapidly growing, poorly circumscribed, mass-forming proliferation that arises from the subcutaneous tissues. It is characterized by the presence of spindle-shaped fibroblasts, round ganglion-like cells, myxoid to collagenous stroma formation, and high mitotic activity. It recurs only rarely following local excision and does not metastasize.","definition_xrefs":["NCIT:C4728"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fasciitis","termid":"MONDO:0004830"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proliferative fasciitis","secondary_identifiers":["SCTID:254737002","MEDGEN:98496","UMLS:C0432528","DOID:9599"],"termid":"MONDO:0004831","xrefs":{"Monarch":{"xref_id":"0004831"}}}


id: PBO:0066797
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 96","termid":"PBO:0066797"}


id: MONDO:0054737
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Fraser syndrome","termid":"MONDO:0009046"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005328"],"is_obsolete":false,"name":"Fraser syndrome 1","secondary_identifiers":["UMLS:C4551480","DOID:0111405","OMIM:219000","MEDGEN:1639061"],"synonyms":[{"name":"FRASRS1","type":"related"},{"name":"Fraser syndrome","type":"related"},{"name":"Fraser syndrome 1","type":"exact"},{"name":"cryptophthalmos with Other malformations","type":"related"},{"name":"cryptophthalmos-syndactyly syndrome","type":"related"}],"termid":"MONDO:0054737","xrefs":{"Monarch":{"xref_id":"0054737"}}}


id: PBO:0081953
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc and ring finger 4","termid":"PBO:0081953"}


id: FYPO:0001721
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal transport during vegetative growth","termid":"FYPO:0005973"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000138","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"abnormal sodium export","synonyms":[{"name":"abnormal cellular sodium export","type":"exact"},{"name":"abnormal sodium export during mitotic cell cycle","type":"related"},{"name":"abnormal sodium export during vegetative growth","type":"exact"},{"name":"abnormal sodium export from cell","type":"exact"},{"name":"abnormal sodium ion export","type":"exact"}],"termid":"FYPO:0001721"}


id: PBO:0005288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RWD domain protein, implicated in translation","termid":"PBO:0005288"}


id: GO:0045017
data:
  {"annotated_genes":["SJAG_03131","SJAG_02328","SJAG_02776","SJAG_02763","SJAG_03066","SJAG_01863","SJAG_00846","SJAG_04545","SJAG_04930","SJAG_01570","SJAG_00825","SJAG_03506","SJAG_01876","SJAG_03563","SJAG_03609","SJAG_03878","SJAG_03115","SJAG_05278","SJAG_04119","SJAG_04323","SJAG_02488","SJAG_04165","SJAG_04337","SJAG_04924","SJAG_04792","SJAG_00999","SJAG_04883","SJAG_01957","SJAG_00812","SJAG_00063","SJAG_00168","SJAG_04975","SJAG_04317","SJAG_01233","SJAG_03524","SJAG_02321","SJAG_02902","SJAG_02980","SJAG_06425","SJAG_02804","SJAG_00114","SJAG_06383","SJAG_00295","SJAG_00296","SJAG_04537","SJAG_04041","SJAG_01416","SJAG_01571","SJAG_01036","SJAG_01519","SJAG_02654","SJAG_05327","SJAG_02613","SJAG_03154","SJAG_02913","SJAG_03292","SJAG_00068","SJAG_01236","SJAG_01918","SJAG_03700","SJAG_00426","SJAG_03170","SJAG_04881","SJAG_01860","SJAG_01227","SJAG_03672","SJAG_03801","SJAG_04628","SJAG_00946","SJAG_02523","SJAG_03162","SJAG_01148","SJAG_05330","SJAG_04319","SJAG_02289","SJAG_00053","SJAG_00831"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[92182],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902635"},{"annotations":[71641,80424,118151,93384],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032049"},{"annotations":[61465,57070],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006657"},{"annotations":[114981,119478,80421,113324],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016024"},{"annotations":[71748],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046474"},{"annotations":[77835,58230,62706,93339,75916,78227,60785,104025,76816,57873,78589,76800,72175,78253,73868,75887,78014,73495,75321,58334,77514,87778,70180,77843,58344,104087,73086,63754,89894,63361],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006506"},{"annotations":[104692,90752],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1902647"},{"annotations":[78124,62421,105207,71880,93401,71417,72016],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006654"},{"annotations":[94989,70664,104650,72812,78619,96747,93402],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006656"},{"annotations":[79497,62179,73903,75730,93403,71387,104292,67430],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006646"},{"annotations":[117306,92975,119123,80607,76945],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006661"},{"annotations":[118765,91559,111565,93568,97028,111441],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046854"},{"annotations":[61808,71785,63336,61658],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036092"},{"annotations":[67429],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006659"},{"annotations":[117835],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1902648"},{"annotations":[90376,77325,71626,74908],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019432"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid biosynthetic process","termid":"GO:0008610"},{"relation_name":"is_a","term_name":"glycerolipid metabolic process","termid":"GO:0046486"}],"gene_count":77,"genes_by_uniquename":{"SJAG_00053":null,"SJAG_00063":null,"SJAG_00068":null,"SJAG_00114":null,"SJAG_00168":null,"SJAG_00295":null,"SJAG_00296":null,"SJAG_00426":null,"SJAG_00812":null,"SJAG_00825":null,"SJAG_00831":null,"SJAG_00846":null,"SJAG_00946":null,"SJAG_00999":null,"SJAG_01036":null,"SJAG_01148":null,"SJAG_01227":null,"SJAG_01233":null,"SJAG_01236":null,"SJAG_01416":null,"SJAG_01519":null,"SJAG_01570":null,"SJAG_01571":null,"SJAG_01860":null,"SJAG_01863":null,"SJAG_01876":null,"SJAG_01918":null,"SJAG_01957":null,"SJAG_02289":null,"SJAG_02321":null,"SJAG_02328":null,"SJAG_02488":null,"SJAG_02523":null,"SJAG_02613":null,"SJAG_02654":null,"SJAG_02763":null,"SJAG_02776":null,"SJAG_02804":null,"SJAG_02902":null,"SJAG_02913":null,"SJAG_02980":null,"SJAG_03066":null,"SJAG_03115":null,"SJAG_03131":null,"SJAG_03154":null,"SJAG_03162":null,"SJAG_03170":null,"SJAG_03292":null,"SJAG_03506":null,"SJAG_03524":null,"SJAG_03563":null,"SJAG_03609":null,"SJAG_03672":null,"SJAG_03700":null,"SJAG_03801":null,"SJAG_03878":null,"SJAG_04041":null,"SJAG_04119":null,"SJAG_04165":null,"SJAG_04317":null,"SJAG_04319":null,"SJAG_04323":null,"SJAG_04337":null,"SJAG_04537":null,"SJAG_04545":null,"SJAG_04628":null,"SJAG_04792":null,"SJAG_04881":null,"SJAG_04883":null,"SJAG_04924":null,"SJAG_04930":null,"SJAG_04975":null,"SJAG_05278":null,"SJAG_05327":null,"SJAG_05330":null,"SJAG_06383":null,"SJAG_06425":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"glycerolipid biosynthetic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000104":null,"GO_REF:0000107":null,"GO_REF:0000108":null,"PMID:25318672":null},"synonyms":[{"name":"glycerolipid anabolism","type":"exact"},{"name":"glycerolipid biosynthesis","type":"exact"},{"name":"glycerolipid formation","type":"exact"},{"name":"glycerolipid synthesis","type":"exact"}],"termid":"GO:0045017","terms_by_termid":{"GO:0006506":null,"GO:0006646":null,"GO:0006654":null,"GO:0006656":null,"GO:0006657":null,"GO:0006659":null,"GO:0006661":null,"GO:0016024":null,"GO:0019432":null,"GO:0032049":null,"GO:0036092":null,"GO:0046474":null,"GO:0046854":null,"GO:1902635":null,"GO:1902647":null,"GO:1902648":null}}


id: PBO:0026955
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_localization_to_new_growing_cell_tip","termid":"PBO:0026955"}


id: GO:1902280
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.","definition_xrefs":["GOC:rb","GOC:TermGenie","PMID:23721653"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ATP-dependent activity","termid":"GO:0043462"},{"relation_name":"is_a","term_name":"regulation of catalytic activity","termid":"GO:0050790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of RNA helicase activity","synonyms":[{"name":"regulation of ATP-dependent RNA helicase activity","type":"exact"}],"termid":"GO:1902280"}


id: MONDO:0859762
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"SLC12A2-related developmental delay-intellectual disability-sensorineural deafness syndrome","termid":"MONDO:0859000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLC12A2-related autosomal dominant infantile-developmental delay-intellectual disability-sensorineural deafness syndrome","secondary_identifiers":["Orphanet:633024"],"termid":"MONDO:0859762","xrefs":{"Monarch":{"xref_id":"0859762"}}}


id: PBO:0061334
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore complex interacting protein family member B12","termid":"PBO:0061334"}


id: PBO:0040906
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BMS1 pseudogene 10","termid":"PBO:0040906"}


id: PBO:0039645
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AP1B1 pseudogene 1","termid":"PBO:0039645"}


id: PBO:0036082
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_histone_H3-K9_acetylation_during_vegetative_growth","termid":"PBO:0036082"}


id: MONDO:0044924
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete acute myeloid leukemia with mutated CEBPA (obsolete MONDO:0044924)","termid":"MONDO:0044924","xrefs":{"Monarch":{"xref_id":"0044924"}}}


id: MOD:01043
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a p-nitrobenzyl group for the hydrogen atom of a carboxyl group.","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"p-nitrobenzyl ester modified residue","synonyms":[{"name":"ONb","type":"exact"}],"termid":"MOD:01043"}


id: PBO:0043897
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cysteine rich protein 1 pseudogene 4","termid":"PBO:0043897"}


id: PBO:0050319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A1 pseudogene 21","termid":"PBO:0050319"}


id: PBO:0057797
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3119-2","termid":"PBO:0057797"}


id: GO:0048000
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O.","definition_xrefs":["EC:1.14.14.88"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"isoflavone 3'-hydroxylase activity","secondary_identifiers":["MetaCyc:RXN-3762","RHEA:22960"],"synonyms":[{"name":"formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating)","type":"related"},{"name":"isoflavone 3'-monooxygenase activity","type":"related"}],"termid":"GO:0048000"}


id: MONDO:1012903
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Waardenburg syndrome that occurs in pigs due to a mutation in the SOX10 gene created by genetic engineering or gene editing.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Waardenburg syndrome, non-human animal","termid":"MONDO:1011447"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Waardenburg syndrome, SOX10-related, pig","secondary_identifiers":["OMIA:002453-9823"],"termid":"MONDO:1012903","xrefs":{"Monarch":{"xref_id":"1012903"}}}


id: PBO:0004380
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase Ypt7","termid":"PBO:0004380"}


id: GO:1901730
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of monensin A.","definition_xrefs":["GOC:TermGenie","GOC:yaf","UniPathway:UPA00178"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alcohol biosynthetic process","termid":"GO:0046165"},{"relation_name":"is_a","term_name":"carboxylic acid biosynthetic process","termid":"GO:0046394"},{"relation_name":"is_a","term_name":"monensin A metabolic process","termid":"GO:1901728"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"monensin A biosynthetic process","synonyms":[{"name":"monensin A anabolism","type":"exact"},{"name":"monensin A biosynthesis","type":"exact"},{"name":"monensin A formation","type":"exact"},{"name":"monensin A synthesis","type":"exact"},{"name":"monensin anabolism","type":"exact"},{"name":"monensin biosynthesis","type":"exact"},{"name":"monensin formation","type":"exact"},{"name":"monensin synthesis","type":"exact"}],"termid":"GO:1901730"}


id: FYPO:0006655
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the unwinding of G-quadruplex DNA structures does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal chromosome organization","termid":"FYPO:0000641"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000641","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abolished G-quadruplex DNA unwinding","synonyms":[{"name":"G-quadruplex DNA unwinding abolished","type":"exact"},{"name":"abolished G-quadruplex DNA unwinding during mitotic cell cycle","type":"related"},{"name":"abolished G-quadruplex DNA unwinding during vegetative growth","type":"exact"},{"name":"abolished G-quartet DNA unwinding","type":"exact"},{"name":"abolished G4 DNA unwinding","type":"exact"}],"termid":"FYPO:0006655"}


id: MONDO:0003333
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mature monodermal teratoma that arises from the ovary and is characterized by the presence of benign, thyroid-type tissues.","definition_xrefs":["NCIT:C40012"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovarian benign neoplasm","termid":"MONDO:0000646"},{"relation_name":"is_a","term_name":"struma ovarii","termid":"MONDO:0006980"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign struma ovarii","secondary_identifiers":["DOID:5209"],"synonyms":[{"name":"benign struma ovarii","type":"exact"},{"name":"struma ovarii, benign","type":"exact"}],"termid":"MONDO:0003333","xrefs":{"Monarch":{"xref_id":"0003333"}}}


id: GO:0070099
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency or extent of a chemokine-mediated signaling pathway.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine-mediated signaling pathway","termid":"GO:0001959"},{"relation_name":"is_a","term_name":"regulation of G protein-coupled receptor signaling pathway","termid":"GO:0008277"},{"relation_name":"regulates","term_name":"chemokine-mediated signaling pathway","termid":"GO:0070098"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of chemokine-mediated signaling pathway","synonyms":[{"name":"regulation of chemokine-mediated signalling pathway","type":"exact"}],"termid":"GO:0070099"}


id: PBO:0058221
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4511","termid":"PBO:0058221"}


id: SO:0001058
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A transcriptional_cis_regulatory_region that restricts the activity of a CRM to a single promoter and which functions only when both itself and an insulator are located between the CRM and the promoter.","definition_xrefs":["SO:regcreative"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcriptional_cis_regulatory_region","termid":"SO:0001055"}],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0001058 promoter_targeting_sequence (obsolete SO:0001058)","synonyms":[{"name":"promoter targeting sequence","type":"exact"}],"termid":"SO:0001058"}


id: FYPO:0002186
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cell population phenotype in which a cell undergoes one or a few rounds of cell division before cells die, resulting in the formation a colony that contains only a few inviable cells that have a lower volume than normal. Up to 6 rounds of cell division (generating 64 cells) may be observed, but 3 divisions or fewer is more typical.","definition_xrefs":["PomBase:mah","PomBase:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable microcolony, small cells (obsolete FYPO:0002186)","synonyms":[{"name":"inviable microcolony, small vegetative cells","type":"exact"}],"termid":"FYPO:0002186"}


id: PBO:0044346
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CYCS pseudogene 30","termid":"PBO:0044346"}


id: MONDO:0014860
data:
  {"annotated_genes":["SJAG_00175"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86418],"is_not":false,"summary":null,"term":"MONDO:0014860"}]},"cv_name":"mondo","definition":"Any polycystic kidney disease in which the cause of the disease is a mutation in the SEC63 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"polycystic liver disease 1","termid":"MONDO:0008265"},{"relation_name":"is_a","term_name":"autosomal dominant polycystic liver disease","termid":"MONDO:0000447"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00175":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0000426","MONDO:0002515"],"is_obsolete":false,"name":"polycystic liver disease 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:934736","OMIM:617004","DOID:0060975","GARD:16174","UMLS:C4310769"],"synonyms":[{"name":"PCLD2","type":"exact"},{"name":"polycystic liver disease 2","type":"exact"},{"name":"polycystic liver disease 2 with or without kidney cysts","type":"related"},{"name":"polycystic liver disease 2; PCLD2","type":"exact"},{"name":"polycystic liver disease type 2","type":"exact"}],"termid":"MONDO:0014860","terms_by_termid":{"MONDO:0014860":null},"xrefs":{"Monarch":{"xref_id":"0014860"}}}


id: GO:0099636
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.","definition_xrefs":["Wikipedia:Cytoplasmic_streaming&oldid=706214009","GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular transport","termid":"GO:0046907"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"cytoplasmic streaming","secondary_identifiers":["Wikipedia:Cytoplasmic_streaming"],"termid":"GO:0099636"}


id: PBO:0034463
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_phosphorylation_during_cellular_response_to_bleomycin","termid":"PBO:0034463"}


id: PBO:0038415
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-directly_negatively_regulates_activity_of","termid":"PBO:0038415"}


id: GO:0100004
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates peroxisome organization.","definition_xrefs":["GOC:cjm","GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of peroxisome organization by transcription from RNA polymerase II promoter (obsolete GO:0100004)","termid":"GO:0100004"}


id: GO:0014727
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.","definition_xrefs":["GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of extraocular skeletal muscle development","termid":"GO:0014725"},{"relation_name":"is_a","term_name":"positive regulation of skeletal muscle tissue development","termid":"GO:0048643"},{"relation_name":"positively_regulates","term_name":"extraocular skeletal muscle development","termid":"GO:0002074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of extraocular skeletal muscle development","termid":"GO:0014727"}


id: MONDO:0008345
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete idiopathic pulmonary fibrosis (obsolete MONDO:0008345)","secondary_identifiers":["NANDO:1200417"],"termid":"MONDO:0008345","xrefs":{"Monarch":{"xref_id":"0008345"}}}


id: GO:0016331
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of embryonic epithelia are generated and organized.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"morphogenesis of an epithelium","termid":"GO:0002009"},{"relation_name":"is_a","term_name":"embryonic morphogenesis","termid":"GO:0048598"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"morphogenesis of embryonic epithelium","termid":"GO:0016331"}


id: PBO:0051421
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable 2-28 (pseudogene)","termid":"PBO:0051421"}


id: GO:0018061
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid.","definition_xrefs":["RESID:AA0128"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-phenylalanine modification","termid":"GO:0018207"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine","synonyms":[{"name":"peptidyl-L-3-phenyllactic acid anabolism from peptidyl-phenylalanine","type":"exact"},{"name":"peptidyl-L-3-phenyllactic acid formation from peptidyl-phenylalanine","type":"exact"},{"name":"peptidyl-L-3-phenyllactic acid synthesis from peptidyl-phenylalanine","type":"exact"}],"termid":"GO:0018061"}


id: GO:0023044
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator.","definition_xrefs":["GOC:mtg_signal"],"gene_count":0,"genotype_count":0,"name":"obsolete signaling via chemical mediator (obsolete GO:0023044)","synonyms":[{"name":"signaling via chemical mediator","type":"exact"},{"name":"signalling via chemical mediator","type":"exact"}],"termid":"GO:0023044"}


id: SO:0001765
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"When a variant from the genomic sequence is rarely found in the general population. The threshold for 'rare' varies between studies.","direct_ancestors":[{"relation_name":"is_a","term_name":"variant_frequency","termid":"SO:0001763"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rare_variant","synonyms":[{"name":"rare variant","type":"exact"}],"termid":"SO:0001765"}


id: GO:0090105
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell development","termid":"GO:0002064"},{"relation_name":"part_of","term_name":"pancreatic epsilon cell differentiation","termid":"GO:0090104"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pancreatic E cell development","termid":"GO:0090105"}


id: PBO:0029036
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_cell_surface","termid":"PBO:0029036"}


id: PBO:0080282
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 45 pseudogene","termid":"PBO:0080282"}


id: PBO:0018170
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNF2 family ATP-dependent DNA helicase Rhp26","termid":"PBO:0018170"}


id: PBO:0076815
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TENM2 antisense RNA 2","termid":"PBO:0076815"}


id: GO:0099130
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an estrogen.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hormone binding","termid":"GO:0042562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"estrogen binding","termid":"GO:0099130"}


id: FYPO:0002659
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is higher than normal when the cell is subject to heat shock.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased cellular trehalose 6-phosphate level","termid":"FYPO:0002658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased cellular trehalose 6-phosphate level during heat shock","synonyms":[{"name":"increased cellular trehalose 6-phosphate level during heat shock during mitotic cell cycle","type":"related"},{"name":"increased cellular trehalose 6-phosphate level during vegetative growth and during heat shock","type":"exact"},{"name":"increased cellular trehalose-6P level during heat shock","type":"exact"},{"name":"increased trehalose 6-phosphate accumulation during heat shock","type":"related"}],"termid":"FYPO:0002659"}


id: MONDO:0035328
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare disorder due to poisoning (obsolete MONDO:0035328)","secondary_identifiers":["Orphanet:556508"],"termid":"MONDO:0035328","xrefs":{"Monarch":{"xref_id":"0035328"}}}


id: GO:0060146
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection.","definition_xrefs":["GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete host gene silencing in virus induced gene silencing (obsolete GO:0060146)","termid":"GO:0060146"}


id: PR:Q10313
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- trl1 gene.","definition_xrefs":["UniProtKB:Q10313","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA ligase 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17G8.01c","synonyms":[{"name":"Spom972h-trl1","type":"exact"}],"termid":"PR:Q10313"}


id: MONDO:0017938
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete X-linked cleft palate and ankyloglossia (obsolete MONDO:0017938)","termid":"MONDO:0017938","xrefs":{"Monarch":{"xref_id":"0017938"}}}


id: PR:Q10060
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mso1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C1F5.05c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1F5.05c","synonyms":[{"name":"Spom972h-mso1","type":"exact"}],"termid":"PR:Q10060"}


id: PBO:0038570
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase","termid":"PBO:0038570"}


id: MOD:00792
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes one (2)H deuterium atom for one (1)H protium atom.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"deuterium substituted residue","termid":"MOD:00786"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deuterium monosubstituted residue","synonyms":[{"name":"D(H)1Res","type":"exact"}],"termid":"MOD:00792"}


id: GO:0009788
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.","definition_xrefs":["GOC:lr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of abscisic acid-activated signaling pathway","termid":"GO:0009787"},{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"negative regulation of cellular response to alcohol","termid":"GO:1905958"},{"relation_name":"negatively_regulates","term_name":"abscisic acid-activated signaling pathway","termid":"GO:0009738"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of abscisic acid-activated signaling pathway","synonyms":[{"name":"down regulation of abscisic acid mediated signaling","type":"exact"},{"name":"down-regulation of abscisic acid mediated signaling","type":"exact"},{"name":"downregulation of abscisic acid mediated signaling","type":"exact"},{"name":"inhibition of abscisic acid mediated signaling","type":"narrow"},{"name":"negative regulation of abscisic acid mediated signaling pathway","type":"related"},{"name":"negative regulation of abscisic acid mediated signalling","type":"exact"}],"termid":"GO:0009788"}


id: PBO:0064231
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PLCH1 antisense RNA 1","termid":"PBO:0064231"}


id: MONDO:0002306
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A blepharoconjunctivitis that is characterized by fissuring, scaling, maceration and erythema of the lateral or medial canthal area.","definition_xrefs":["DOID:2455"],"direct_ancestors":[{"relation_name":"is_a","term_name":"blepharoconjunctivitis","termid":"MONDO:0002307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"angular blepharoconjunctivitis","secondary_identifiers":["MEDGEN:509810","ICD9:372.21","SCTID:69397000","UMLS:C0155149","icd11.foundation:602571061"],"termid":"MONDO:0002306","xrefs":{"Monarch":{"xref_id":"0002306"}}}


id: GO:0018187
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide.","definition_xrefs":["RESID:AA0281"],"gene_count":0,"genotype_count":0,"name":"obsolete molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide (obsolete GO:0018187)","termid":"GO:0018187"}


id: PATO:0002084
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"The period after death of the organism.","definition_xrefs":["thefreedictionary:thefreedictionary"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0002084 post-mortem (obsolete PATO:0002084)","termid":"PATO:0002084"}


id: PBO:0018146
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eisosome assembly protein eis1","termid":"PBO:0018146"}


id: PBO:0041009
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BORCS8 pseudogene 1","termid":"PBO:0041009"}


id: GO:0052151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont initiates, promotes, or enhances the normal execution of host apoptosis, leading to an increase in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:19801898","PMID:11805081","PMID:18037263","PMID:29571981"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated killing of host cell","termid":"GO:0001907"},{"relation_name":"is_a","term_name":"symbiont-mediated activation of host programmed cell death","termid":"GO:0052042"},{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host apoptosis","termid":"GO:0052150"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated activation of host apoptosis","secondary_identifiers":["GO:0039651","GO:0052030","GO:0060139","GO:0033669"],"synonyms":[{"name":"activation by organism of host apoptosis","type":"exact"},{"name":"activation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"activation by symbiont of host apoptosis","type":"narrow"},{"name":"induction by organism of host apoptotic programmed cell death","type":"exact"},{"name":"induction by symbiont of host apoptosis","type":"exact"},{"name":"positive regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"positive regulation by symbiont of host apoptosis","type":"narrow"},{"name":"positive regulation by symbiont of host apoptotic process","type":"exact"},{"name":"positive regulation by virus of host apoptosis","type":"narrow"},{"name":"stimulation by symbiont of host apoptosis","type":"narrow"},{"name":"up regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"up regulation by symbiont of host apoptosis","type":"exact"},{"name":"up-regulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"up-regulation by symbiont of host apoptosis","type":"exact"},{"name":"upregulation by organism of host apoptotic programmed cell death","type":"exact"},{"name":"upregulation by symbiont of host apoptosis","type":"exact"}],"termid":"GO:0052151"}


id: SO:0000246
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A attribute describing the addition of a poly A tail to the 3' end of a mRNA molecule.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA_attribute","termid":"SO:0000863"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polyadenylated","termid":"SO:0000246"}


id: FYPO:0006628
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the plasma membrane is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased phosphatidylinositol phosphate level in plasma membrane","termid":"FYPO:0006222"},{"relation_name":"is_a","term_name":"decreased cellular phosphatidylinositol-4-phosphate level","termid":"FYPO:0006775"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased phosphatidylinositol-4-phosphate level in plasma membrane","synonyms":[{"name":"decreased 1-phosphatidyl-1D-myo-inositol 4-phosphate level in plasma membrane","type":"exact"},{"name":"decreased phosphatidylinositol-4-phosphate level in cell membrane","type":"exact"},{"name":"decreased phosphatidylinositol-4-phosphate level in plasma membrane during mitotic cell cycle","type":"related"},{"name":"decreased phosphatidylinositol-4-phosphate level in plasma membrane during vegetative growth","type":"exact"},{"name":"decreased plasma membrane PI(5)P level","type":"exact"},{"name":"decreased plasma membrane phosphatidylinositol-4-phosphate level","type":"exact"},{"name":"reduced phosphatidylinositol-4-phosphate level in plasma membrane","type":"exact"}],"termid":"FYPO:0006628"}


id: MOD:01277
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Other -","definition_xrefs":["Unimod:253#C","PubMed:11283024"],"direct_ancestors":[{"relation_name":"is_a","term_name":"crotonaldehyde","termid":"MOD:00576"},{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"crotonaldehyde - site C","synonyms":[{"name":"Crotonaldehyde","type":"related"}],"termid":"MOD:01277"}


id: GO:0051726
data:
  {"annotated_genes":["SJAG_03350","SJAG_04884","SJAG_04468","SJAG_02807","SJAG_00266","SJAG_03126","SJAG_01386","SJAG_02342","SJAG_01297","SJAG_02336","SJAG_03067","SJAG_02026","SJAG_01515","SJAG_00071","SJAG_04813","SJAG_02514","SJAG_01901","SJAG_03581","SJAG_04666","SJAG_05288","SJAG_03692","SJAG_02232","SJAG_05978","SJAG_03371","SJAG_04126","SJAG_03529","SJAG_03695","SJAG_03854","SJAG_01679","SJAG_01330","SJAG_06270","SJAG_01680","SJAG_02810","SJAG_01000","SJAG_05373","SJAG_04551","SJAG_03342","SJAG_00433","SJAG_00229","SJAG_01677","SJAG_01076","SJAG_01787","SJAG_01188","SJAG_02712","SJAG_00318","SJAG_03936","SJAG_03356","SJAG_04394","SJAG_02451","SJAG_04968","SJAG_04457","SJAG_04699","SJAG_03353","SJAG_02771","SJAG_05153","SJAG_01114","SJAG_01863","SJAG_01584","SJAG_00486","SJAG_04597","SJAG_01429","SJAG_00845","SJAG_04771","SJAG_04259","SJAG_01956","SJAG_00256","SJAG_01113","SJAG_02645","SJAG_00214","SJAG_02104","SJAG_03704","SJAG_01345","SJAG_06592","SJAG_00216","SJAG_02332","SJAG_00680","SJAG_01456","SJAG_02498","SJAG_03575","SJAG_04412","SJAG_01146","SJAG_05236","SJAG_02563","SJAG_00117","SJAG_04943","SJAG_05346","SJAG_02858","SJAG_03942","SJAG_03591","SJAG_00460","SJAG_01205","SJAG_00883","SJAG_04853","SJAG_00600","SJAG_04280","SJAG_00100","SJAG_03602","SJAG_02162","SJAG_03160","SJAG_01082","SJAG_02576","SJAG_04671","SJAG_03898","SJAG_01837","SJAG_03501","SJAG_04573","SJAG_03376","SJAG_00364","SJAG_04455","SJAG_06638","SJAG_03624","SJAG_02058","SJAG_01050","SJAG_00840","SJAG_00993","SJAG_00640","SJAG_00514","SJAG_01118","SJAG_04509","SJAG_01855","SJAG_04999","SJAG_03720","SJAG_00082","SJAG_03689","SJAG_05290","SJAG_03438","SJAG_01805","SJAG_03681","SJAG_04287","SJAG_00623","SJAG_01708","SJAG_03525","SJAG_01825","SJAG_00987","SJAG_02098","SJAG_02736","SJAG_02380","SJAG_00169","SJAG_02795","SJAG_04140","SJAG_01401","SJAG_05329","SJAG_02592","SJAG_00439","SJAG_04486","SJAG_00991","SJAG_02266","SJAG_00457","SJAG_03508","SJAG_00996","SJAG_01790","SJAG_01210","SJAG_00429","SJAG_01605","SJAG_02214","SJAG_03592","SJAG_03026","SJAG_01873","SJAG_03048","SJAG_01311","SJAG_00526","SJAG_03699","SJAG_03073","SJAG_02838","SJAG_02404","SJAG_00823","SJAG_03351","SJAG_04464","SJAG_00244","SJAG_00666","SJAG_02723","SJAG_03927","SJAG_01068","SJAG_01084","SJAG_03486","SJAG_02074","SJAG_03309","SJAG_02621","SJAG_03327","SJAG_03887","SJAG_01464","SJAG_02392","SJAG_02481","SJAG_00369","SJAG_01044","SJAG_01801","SJAG_01010","SJAG_00145","SJAG_02169","SJAG_04332","SJAG_03631","SJAG_03300","SJAG_04682","SJAG_00327","SJAG_01716","SJAG_04205","SJAG_04776"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[108277],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010846"},{"annotations":[95492,90684],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051728"},{"annotations":[108563,104208,114574,99912,116202,91063,114086,107544,112268],"is_not":false,"rel_names":["positively_regulates","regulates","is_a","negatively_regulates"],"summary":null,"term":"GO:1902426"},{"annotations":[114801,106634],"is_not":false,"rel_names":["regulates","is_a","negatively_regulates"],"summary":null,"term":"GO:1905318"},{"annotations":[79160],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044778"},{"annotations":[116360,91770,106930],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033315"},{"annotations":[116361,106931,114564,89401],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051598"},{"annotations":[116969,75747],"is_not":false,"rel_names":["negatively_regulates","is_a","regulates"],"summary":null,"term":"GO:0033316"},{"annotations":[99016,100459],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990949"},{"annotations":[102604,100460],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990950"},{"annotations":[73404,71077,78750],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007091"},{"annotations":[101754,116306,94746,100858,90337],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044878"},{"annotations":[78351,80354,93909,114772,116534,111506,116307],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044773"},{"annotations":[100859,109624,106933,72793,75104,79825,117103,99681,117576,116362,91771,112343,79166,94303,71471,99514,117404],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033314"},{"annotations":[101936,89285,102673,109199,116204],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031568"},{"annotations":[91648,109977],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031571"},{"annotations":[116308,96183,98752,94878],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031569"},{"annotations":[90552,109625,118013,89462,75598,101369,100860,99683,117318,112038,91772,92134,106934,72791,79767],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007095"},{"annotations":[79164,74254,79540,91773,94879,74778,102674,79772,116364,107975,99684,89463,101179,106935,112344,90787,112039,96344,89508],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031573"},{"annotations":[115859,106636,102113,114804,110213,99756],"is_not":false,"rel_names":["negatively_regulates","is_a","regulates"],"summary":null,"term":"GO:0007094"},{"annotations":[111507],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0075297"},{"annotations":[102676],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902424"},{"annotations":[102677,106132,106964,104757,109575,118667,106291],"is_not":false,"rel_names":["regulates","negatively_regulates","is_a"],"summary":null,"term":"GO:0110045"},{"annotations":[98600],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000432"},{"annotations":[68279,102680],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001100"},{"annotations":[116285,99885,118394],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070317"},{"annotations":[93674,92500,99199,92080],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000134"},{"annotations":[93561,94706,107329,78832,106965,104813,93268,93910,108883,111743,112786,114773,101314,112128],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010972"},{"annotations":[78836,70953],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110031"},{"annotations":[116683],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051447"},{"annotations":[99017],"is_not":false,"rel_names":["is_a","regulates","negatively_regulates"],"summary":null,"term":"GO:1902103"},{"annotations":[102681],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903500"},{"annotations":[104012],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903472"},{"annotations":[117149],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903464"},{"annotations":[99991,107410,93185,102460],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902413"},{"annotations":[102683,109203,98097],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903467"},{"annotations":[103593],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000816"},{"annotations":[94538],"is_not":false,"rel_names":["is_a","negatively_regulates","positively_regulates","regulates"],"summary":null,"term":"GO:0140499"},{"annotations":[102684],"is_not":false,"rel_names":["part_of","is_a"],"summary":null,"term":"GO:1902845"},{"annotations":[102686],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905757"},{"annotations":[108280],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045128"},{"annotations":[116205,92072,107546,105361,95972,107851,93186,99914,73126,91067,110477,93804,101592,93270,107411],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031030"},{"annotations":[115641,92081,106577,106673,106895,107716],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045875"},{"annotations":[102605],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0075296"},{"annotations":[91068],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903024"},{"annotations":[105500,112269,116311],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902425"},{"annotations":[116784,118533],"is_not":false,"rel_names":["positively_regulates","is_a","regulates"],"summary":null,"term":"GO:0140648"},{"annotations":[112346,117578,103637],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903468"},{"annotations":[102687,112270,90339,94092],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031536"},{"annotations":[102688,106292,109494,117372,106971,106136],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1900087"},{"annotations":[110653,88390,94143,94748,98753,71139,108885,94709,99323,92478,92074,88399,116974,103805,107547,73885,111509,116785,102073],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010971"},{"annotations":[101704,88192],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905287"},{"annotations":[73890],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110032"},{"annotations":[102689,116535,106936,89402],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904514"},{"annotations":[114091],"is_not":false,"rel_names":["positively_regulates","is_a","regulates"],"summary":null,"term":"GO:1905326"},{"annotations":[107369,97375,119392,119393],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051446"},{"annotations":[102692,108668],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905263"},{"annotations":[95495],"is_not":false,"rel_names":["regulates","positively_regulates","is_a"],"summary":null,"term":"GO:1905191"},{"annotations":[94749,90340],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903501"},{"annotations":[113670,94919,87876,110832,94750],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903473"},{"annotations":[102693],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903465"},{"annotations":[116976],"is_not":false,"rel_names":["is_a","positively_regulates","regulates"],"summary":null,"term":"GO:0090267"},{"annotations":[116977,102694],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903380"},{"annotations":[111075,104017,91109,119860],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903617"},{"annotations":[94145,106701,113671,92760,78274,105501,115774,90210,118193,107362],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140281"},{"annotations":[100461,102695,102424,94146,115073,111683,98022],"is_not":false,"rel_names":["regulates","positively_regulates","is_a"],"summary":null,"term":"GO:0045842"},{"annotations":[106452,89341,116719],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120292"},{"annotations":[116978],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905824"},{"annotations":[90342,94147,116979,102696,111510],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140429"},{"annotations":[99927,96932,99932],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901970"},{"annotations":[94751,90343],"is_not":false,"rel_names":["is_a","part_of"],"summary":null,"term":"GO:1902846"},{"annotations":[111744],"is_not":false,"rel_names":["is_a","part_of"],"summary":null,"term":"GO:0110161"},{"annotations":[92761,94753,87877],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905758"},{"annotations":[89403],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010845"},{"annotations":[92762,87860],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140748"},{"annotations":[110833,87878,90344,94149,102700],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031031"},{"annotations":[107718],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045876"},{"annotations":[97513],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032215"},{"annotations":[78579],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031991"},{"annotations":[92529],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034307"},{"annotations":[117230],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903023"},{"annotations":[106674],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901987"},{"annotations":[94882,101939,109354,105236],"is_not":false,"rel_names":["regulates","is_a"],"summary":null,"term":"GO:0110044"},{"annotations":[88239,78580,75753],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032955"},{"annotations":[70490,111324],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007096"},{"annotations":[112274,71956],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010389"},{"annotations":[94227,110493],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090006"},{"annotations":[102706],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0062123"},{"annotations":[101655],"is_not":false,"rel_names":["regulates","is_a"],"summary":null,"term":"GO:1905325"},{"annotations":[104644,92479,93643,90154,94714],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051445"},{"annotations":[108669],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901993"},{"annotations":[97268],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0040020"},{"annotations":[119711,94151],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903499"},{"annotations":[74355],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007346"},{"annotations":[77401,117821,107455,90156,118994,92185,109522,101261,103806],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902412"},{"annotations":[111684,101706,88194],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902472"},{"annotations":[111237],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007088"},{"annotations":[94179,103981],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905557"},{"annotations":[71909],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901673"},{"annotations":[111326],"is_not":false,"rel_names":["part_of","is_a"],"summary":null,"term":"GO:0032888"},{"annotations":[115354],"is_not":false,"rel_names":["is_a","part_of"],"summary":null,"term":"GO:0110162"},{"annotations":[90214],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0060236"},{"annotations":[89510,116587,94716],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010520"},{"annotations":[101157],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007063"},{"annotations":[116982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904967"},{"annotations":[116536],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0062209"},{"annotations":[116206,92086,77087,75157,109205,115643],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007089"}]},"cv_name":"biological_process","definition":"Any process that modulates the rate or extent of progression through the cell cycle.","definition_xrefs":["GOC:tb","GOC:dph","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular process","termid":"GO:0050794"},{"relation_name":"regulates","term_name":"cell cycle","termid":"GO:0007049"}],"gene_count":197,"genes_by_uniquename":{"SJAG_00071":null,"SJAG_00082":null,"SJAG_00100":null,"SJAG_00117":null,"SJAG_00145":null,"SJAG_00169":null,"SJAG_00214":null,"SJAG_00216":null,"SJAG_00229":null,"SJAG_00244":null,"SJAG_00256":null,"SJAG_00266":null,"SJAG_00318":null,"SJAG_00327":null,"SJAG_00364":null,"SJAG_00369":null,"SJAG_00429":null,"SJAG_00433":null,"SJAG_00439":null,"SJAG_00457":null,"SJAG_00460":null,"SJAG_00486":null,"SJAG_00514":null,"SJAG_00526":null,"SJAG_00600":null,"SJAG_00623":null,"SJAG_00640":null,"SJAG_00666":null,"SJAG_00680":null,"SJAG_00823":null,"SJAG_00840":null,"SJAG_00845":null,"SJAG_00883":null,"SJAG_00987":null,"SJAG_00991":null,"SJAG_00993":null,"SJAG_00996":null,"SJAG_01000":null,"SJAG_01010":null,"SJAG_01044":null,"SJAG_01050":null,"SJAG_01068":null,"SJAG_01076":null,"SJAG_01082":null,"SJAG_01084":null,"SJAG_01113":null,"SJAG_01114":null,"SJAG_01118":null,"SJAG_01146":null,"SJAG_01188":null,"SJAG_01205":null,"SJAG_01210":null,"SJAG_01297":null,"SJAG_01311":null,"SJAG_01330":null,"SJAG_01345":null,"SJAG_01386":null,"SJAG_01401":null,"SJAG_01429":null,"SJAG_01456":null,"SJAG_01464":null,"SJAG_01515":null,"SJAG_01584":null,"SJAG_01605":null,"SJAG_01677":null,"SJAG_01679":null,"SJAG_01680":null,"SJAG_01708":null,"SJAG_01716":null,"SJAG_01787":null,"SJAG_01790":null,"SJAG_01801":null,"SJAG_01805":null,"SJAG_01825":null,"SJAG_01837":null,"SJAG_01855":null,"SJAG_01863":null,"SJAG_01873":null,"SJAG_01901":null,"SJAG_01956":null,"SJAG_02026":null,"SJAG_02058":null,"SJAG_02074":null,"SJAG_02098":null,"SJAG_02104":null,"SJAG_02162":null,"SJAG_02169":null,"SJAG_02214":null,"SJAG_02232":null,"SJAG_02266":null,"SJAG_02332":null,"SJAG_02336":null,"SJAG_02342":null,"SJAG_02380":null,"SJAG_02392":null,"SJAG_02404":null,"SJAG_02451":null,"SJAG_02481":null,"SJAG_02498":null,"SJAG_02514":null,"SJAG_02563":null,"SJAG_02576":null,"SJAG_02592":null,"SJAG_02621":null,"SJAG_02645":null,"SJAG_02712":null,"SJAG_02723":null,"SJAG_02736":null,"SJAG_02771":null,"SJAG_02795":null,"SJAG_02807":null,"SJAG_02810":null,"SJAG_02838":null,"SJAG_02858":null,"SJAG_03026":null,"SJAG_03048":null,"SJAG_03067":null,"SJAG_03073":null,"SJAG_03126":null,"SJAG_03160":null,"SJAG_03300":null,"SJAG_03309":null,"SJAG_03327":null,"SJAG_03342":null,"SJAG_03350":null,"SJAG_03351":null,"SJAG_03353":null,"SJAG_03356":null,"SJAG_03371":null,"SJAG_03376":null,"SJAG_03438":null,"SJAG_03486":null,"SJAG_03501":null,"SJAG_03508":null,"SJAG_03525":null,"SJAG_03529":null,"SJAG_03575":null,"SJAG_03581":null,"SJAG_03591":null,"SJAG_03592":null,"SJAG_03602":null,"SJAG_03624":null,"SJAG_03631":null,"SJAG_03681":null,"SJAG_03689":null,"SJAG_03692":null,"SJAG_03695":null,"SJAG_03699":null,"SJAG_03704":null,"SJAG_03720":null,"SJAG_03854":null,"SJAG_03887":null,"SJAG_03898":null,"SJAG_03927":null,"SJAG_03936":null,"SJAG_03942":null,"SJAG_04126":null,"SJAG_04140":null,"SJAG_04205":null,"SJAG_04259":null,"SJAG_04280":null,"SJAG_04287":null,"SJAG_04332":null,"SJAG_04394":null,"SJAG_04412":null,"SJAG_04455":null,"SJAG_04457":null,"SJAG_04464":null,"SJAG_04468":null,"SJAG_04486":null,"SJAG_04509":null,"SJAG_04551":null,"SJAG_04573":null,"SJAG_04597":null,"SJAG_04666":null,"SJAG_04671":null,"SJAG_04682":null,"SJAG_04699":null,"SJAG_04771":null,"SJAG_04776":null,"SJAG_04813":null,"SJAG_04853":null,"SJAG_04884":null,"SJAG_04943":null,"SJAG_04968":null,"SJAG_04999":null,"SJAG_05153":null,"SJAG_05236":null,"SJAG_05288":null,"SJAG_05290":null,"SJAG_05329":null,"SJAG_05346":null,"SJAG_05373":null,"SJAG_05978":null,"SJAG_06270":null,"SJAG_06592":null,"SJAG_06638":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"regulation of cell cycle","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"PMID:25866389":null,"PMID:32915139":null},"secondary_identifiers":["GO:0000074","GO:0071850","GO:0071158","Reactome:R-HSA-156711","Reactome:R-HSA-380972","GO:0071156","GO:0007050","GO:0071157"],"synonyms":[{"name":"arrest of mitotic cell cycle progression","type":"narrow"},{"name":"cell cycle arrest","type":"narrow"},{"name":"cell cycle modulation","type":"exact"},{"name":"cell cycle regulation","type":"exact"},{"name":"cell cycle regulator","type":"related"},{"name":"control of cell cycle progression","type":"exact"},{"name":"mitotic cell cycle arrest","type":"narrow"},{"name":"modulation of cell cycle progression","type":"exact"},{"name":"negative regulation of cell cycle arrest","type":"narrow"},{"name":"positive regulation of cell cycle arrest","type":"narrow"},{"name":"regulation of cell cycle arrest","type":"narrow"},{"name":"regulation of cell cycle progression","type":"exact"},{"name":"regulation of progression through cell cycle","type":"exact"},{"name":"tumor suppressor","type":"related"}],"termid":"GO:0051726","terms_by_termid":{"GO:0001100":null,"GO:0007063":null,"GO:0007088":null,"GO:0007089":null,"GO:0007091":null,"GO:0007094":null,"GO:0007095":null,"GO:0007096":null,"GO:0007346":null,"GO:0010389":null,"GO:0010520":null,"GO:0010845":null,"GO:0010846":null,"GO:0010971":null,"GO:0010972":null,"GO:0031030":null,"GO:0031031":null,"GO:0031536":null,"GO:0031568":null,"GO:0031569":null,"GO:0031571":null,"GO:0031573":null,"GO:0031991":null,"GO:0032215":null,"GO:0032888":null,"GO:0032955":null,"GO:0033314":null,"GO:0033315":null,"GO:0033316":null,"GO:0034307":null,"GO:0040020":null,"GO:0044773":null,"GO:0044778":null,"GO:0044878":null,"GO:0045128":null,"GO:0045842":null,"GO:0045875":null,"GO:0045876":null,"GO:0051445":null,"GO:0051446":null,"GO:0051447":null,"GO:0051598":null,"GO:0051728":null,"GO:0060236":null,"GO:0062123":null,"GO:0062209":null,"GO:0070317":null,"GO:0075296":null,"GO:0075297":null,"GO:0090006":null,"GO:0090267":null,"GO:0110031":null,"GO:0110032":null,"GO:0110044":null,"GO:0110045":null,"GO:0110161":null,"GO:0110162":null,"GO:0120292":null,"GO:0120306":null,"GO:0140281":null,"GO:0140429":null,"GO:0140499":null,"GO:0140648":null,"GO:0140748":null,"GO:1900087":null,"GO:1901673":null,"GO:1901970":null,"GO:1901987":null,"GO:1901993":null,"GO:1902103":null,"GO:1902412":null,"GO:1902413":null,"GO:1902424":null,"GO:1902425":null,"GO:1902426":null,"GO:1902472":null,"GO:1902845":null,"GO:1902846":null,"GO:1903023":null,"GO:1903024":null,"GO:1903380":null,"GO:1903464":null,"GO:1903465":null,"GO:1903467":null,"GO:1903468":null,"GO:1903472":null,"GO:1903473":null,"GO:1903499":null,"GO:1903500":null,"GO:1903501":null,"GO:1903617":null,"GO:1904514":null,"GO:1904967":null,"GO:1905191":null,"GO:1905263":null,"GO:1905287":null,"GO:1905318":null,"GO:1905325":null,"GO:1905326":null,"GO:1905557":null,"GO:1905757":null,"GO:1905758":null,"GO:1905824":null,"GO:1990949":null,"GO:1990950":null,"GO:2000134":null,"GO:2000432":null,"GO:2000816":null}}


id: PBO:0036194
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-mitotic_spindle_elongation_without_chromosome_separation","termid":"PBO:0036194"}


id: GO:0001840
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.","definition_xrefs":["GOC:ef","ISBN:0878932437","GOC:dph","ISBN:0878932585"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelium development","termid":"GO:0060429"},{"relation_name":"part_of","term_name":"chordate embryonic development","termid":"GO:0043009"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neural plate development","termid":"GO:0001840"}


id: PBO:0049731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hepatitis A virus cellular receptor 1 pseudogene 2","termid":"PBO:0049731"}


id: PBO:0058743
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6867","termid":"PBO:0058743"}


id: FYPO:0006734
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins begins later than normal.","definition_xrefs":["PMID:22718908","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to chromatin during vegetative growth","termid":"FYPO:0000452"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000138","FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"delayed onset of protein localization to chromatin at replication origin","synonyms":[{"name":"delayed onset of protein localisation to chromatin at replication origin","type":"exact"},{"name":"delayed onset of protein localization to chromatin at replication origins during mitotic cell cycle","type":"related"},{"name":"delayed onset of protein localization to chromatin at replication origins during vegetative growth","type":"exact"},{"name":"delayed protein localization to chromatin at replication origin","type":"exact"}],"termid":"FYPO:0006734"}


id: MONDO:0015639
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Benign partial epilepsy with secondarily generalized seizures in infancy is a rare infantile epilepsy syndrome characterized by seizures presenting with motion arrest and staring. They are followed by generalized tonic-clonic convulsions with normal interictal EEG and focal paroxysmal discharges, followed by generalization in ictal EEG. Seizures usually occur in clusters and are responsive to treatment. Psychomotor development is normal.","definition_xrefs":["Orphanet:166302"],"direct_ancestors":[{"relation_name":"is_a","term_name":"benign non-familial infantile seizures","termid":"MONDO:0015637"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"benign partial epilepsy with secondarily generalized seizures in infancy","secondary_identifiers":["icd11.foundation:413225821","UMLS:C4749728","GARD:20073","MEDGEN:1656339"],"termid":"MONDO:0015639","xrefs":{"Monarch":{"xref_id":"0015639"}}}


id: MONDO:0002491
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"substance-related disorder","termid":"MONDO:0002494"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"substance abuse","secondary_identifiers":["SCTID:66214007","MEDGEN:152849","UMLS:C0740858","DOID:302","ICD9:305.90"],"termid":"MONDO:0002491","xrefs":{"Monarch":{"xref_id":"0002491"}}}


id: FYPO:0007899
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, localization of a protein to the actomyosin contractile ring is increased.","definition_xrefs":["PMID:34613787","PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to actomyosin contractile ring","termid":"FYPO:0002560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000032"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0000631","FYPO:0000032"],"is_obsolete":false,"name":"increased rate of protein localization to actomyosin contractile ring","synonyms":[{"name":"increased rate of protein localisation to actomyosin contractile ring","type":"exact"},{"name":"increased rate of protein localization to actomyosin contractile ring during vegetative growth","type":"exact"},{"name":"increased rate of protein localization to actomyosin contractile ring involved in mitotic cytokinesis","type":"exact"},{"name":"increased rate of protein localization to cytokinetic contractile ring","type":"exact"},{"name":"increased rate of protein localization to mitotic contractile ring","type":"exact"}],"termid":"FYPO:0007899"}


id: PATO:0001911
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A behavioral quality inhering in a bearer by virtue of the bearer's exhibiting movement in a circular course.","definition_xrefs":["PATOC:mb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"movement behavioral quality","termid":"PATO:0002076"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"circling","termid":"PATO:0001911"}


id: MONDO:0020350
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Miller-Fisher syndrome (obsolete MONDO:0020350)","termid":"MONDO:0020350","xrefs":{"Monarch":{"xref_id":"0020350"}}}


id: MONDO:0014248
data:
  {"annotated_genes":["SJAG_04697"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86171],"is_not":false,"summary":null,"term":"MONDO:0014248"}]},"cv_name":"mondo","definition":"SLC35A3-CDG is a form of congenital disorders of N-linked glycosylation characterized by distal arthrogryposis (mild flexion contractures of the fingers, deviation of the distal phalanges, swan-neck deformity), retromicrognathia, general muscle hypotonia, delayed psychomotor development, autism spectrum disorder (speech delay, abnormal use of speech, difficulties in initiating, understanding and maintaining social interaction, limited non-verbal communication and repetitive behavior), seizures, microcephaly and mild to moderate intellectual disability that becomes apparent with age. The disease is caused by mutations in the gene SLC35A3 (1p21).","definition_xrefs":["Orphanet:370943"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"disorder of protein N-glycosylation","termid":"MONDO:0017740"},{"relation_name":"is_a","term_name":"distal arthrogryposis","termid":"MONDO:0019942"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04697":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0024322","MONDO:0005066"],"is_obsolete":false,"name":"autism spectrum disorder - epilepsy - arthrogryposis syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:615553","GARD:17604","UMLS:C3809910","MEDGEN:816240"],"synonyms":[{"name":"AMRS","type":"related"},{"name":"SLC35A3-CDG","type":"exact"},{"name":"arthrogryposis, impaired intellectual development, and seizures","type":"exact"},{"name":"arthrogryposis, intellectual disability, and seizures","type":"related"},{"name":"arthrogryposis, mental retardation, and seizures","type":"related"}],"termid":"MONDO:0014248","terms_by_termid":{"MONDO:0014248":null},"xrefs":{"Monarch":{"xref_id":"0014248"}}}


id: GO:0030081
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.","definition_xrefs":["GOC:lr","GOC:kd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"light-harvesting complex, peripheral complex","termid":"GO:0030079"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0031410","GO:0005575"],"is_obsolete":false,"name":"B800-820 antenna complex","synonyms":[{"name":"LH3 complex","type":"exact"},{"name":"light harvesting complex III","type":"exact"}],"termid":"GO:0030081"}


id: PBO:0003372
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Another DNA Ligase","termid":"PBO:0003372"}


id: PBO:0028750
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_mitotic_spindle_pole_body","termid":"PBO:0028750"}


id: GO:0046296
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycolate metabolic process","termid":"GO:0009441"},{"relation_name":"is_a","term_name":"primary alcohol catabolic process","termid":"GO:0034310"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"glycolate catabolic process","synonyms":[{"name":"glycolate breakdown","type":"exact"},{"name":"glycolate catabolism","type":"exact"},{"name":"glycolate degradation","type":"exact"}],"termid":"GO:0046296"}


id: PBO:0036144
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_export_from_nucleus_during_glucose_starvation","termid":"PBO:0036144"}


id: PBO:0047895
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, aphidicolin type, common, fra(7)(p22)","termid":"PBO:0047895"}


id: PBO:0054450
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1847","termid":"PBO:0054450"}


id: MONDO:1011345
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Poisoning that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-human animal disease","termid":"MONDO:0005583"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"poisoning, non-human animal","termid":"MONDO:1011345","xrefs":{"Monarch":{"xref_id":"1011345"}}}


id: PBO:0086334
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; expressed at a very low level; potential role in resistance to oxidative stress and modulation of the PKA pathway; GEX2 has a paralog, GEX1, that arose from a segmental duplication","termid":"PBO:0086334"}


id: MONDO:0008851
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autism (obsolete MONDO:0008851)","termid":"MONDO:0008851","xrefs":{"Monarch":{"xref_id":"0008851"}}}


id: GO:0008676
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H+ + phosphate.","definition_xrefs":["RHEA:14053","EC:2.5.1.55"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase activity, transferring alkyl or aryl (other than methyl) groups","termid":"GO:0016765"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016765"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0003674","GO:0016765"],"is_obsolete":false,"name":"3-deoxy-8-phosphooctulonate synthase activity","secondary_identifiers":["MetaCyc:KDO-8PSYNTH-RXN","KEGG_REACTION:R03254"],"synonyms":[{"name":"2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity","type":"related"},{"name":"2-dehydro-3-deoxy-phosphooctonate aldolase activity","type":"related"},{"name":"2-dehydro-3-deoxyphosphooctonate aldolase activity","type":"exact"},{"name":"2-keto-3-deoxy-8-phosphooctonic synthetase activity","type":"related"},{"name":"3-deoxy-D-manno-octulosonate-8-phosphate synthase activity","type":"related"},{"name":"3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity","type":"related"},{"name":"3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity","type":"related"},{"name":"3-deoxyoctulosonic 8-phosphate synthetase activity","type":"related"},{"name":"KDO-8-P synthase activity","type":"related"},{"name":"KDO-8-phosphate synthetase activity","type":"related"},{"name":"KDOP synthase activity","type":"related"},{"name":"phospho-2-keto-3-deoxyoctonate aldolase activity","type":"related"},{"name":"phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)","type":"related"}],"termid":"GO:0008676"}


id: GO:0016303
data:
  {"annotated_genes":["SJAG_00114"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71779],"is_not":false,"summary":null,"term":"GO:0016303"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + H+.","definition_xrefs":["EC:2.7.1.137","RHEA:12709"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylinositol kinase activity","termid":"GO:0052742"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00114":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016301"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0016301","GO:0003824"],"is_obsolete":false,"name":"1-phosphatidylinositol-3-kinase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-2045911","Reactome:R-HSA-109699","Reactome:R-HSA-1675961","Reactome:R-HSA-1676024","GO:0004429","MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN","Reactome:R-HSA-1433514","Reactome:R-HSA-1675939","Reactome:R-HSA-9670433","KEGG_REACTION:R03362","Reactome:R-HSA-5672012","Reactome:R-HSA-6798174","Reactome:R-HSA-9680389"],"synonyms":[{"name":"1-phosphatidylinositol 3-kinase activity","type":"exact"},{"name":"PI3-kinase activity","type":"exact"},{"name":"PI3K","type":"exact"},{"name":"PtdIns-3-kinase activity","type":"exact"},{"name":"phosphatidylinositol 3-kinase activity, class I","type":"narrow"},{"name":"phosphatidylinositol 3-kinase activity, class II","type":"narrow"},{"name":"phosphatidylinositol 3-kinase activity, class III","type":"narrow"},{"name":"phosphatidylinositol 3-kinase, class I, catalyst activity","type":"narrow"},{"name":"type I phosphatidylinositol kinase activity","type":"narrow"},{"name":"type III phosphoinositide 3-kinase activity","type":"narrow"}],"termid":"GO:0016303","terms_by_termid":{"GO:0016303":null}}


id: MONDO:0030919
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant non-syndromic intellectual disability","termid":"MONDO:0015802"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"intellectual disability, autosomal dominant 53","secondary_identifiers":["GARD:16473","DOID:0080228","MEDGEN:1623344","UMLS:C4540481","OMIM:617798","EFO:0009165"],"synonyms":[{"name":"MRD53","type":"related"},{"name":"autosomal dominant intellectual disability 53","type":"related"},{"name":"autosomal dominant mental retardation 53","type":"related"},{"name":"intellectual disability, autosomal dominant 53","type":"exact"},{"name":"mental retardation, autosomal dominant 53","type":"related"}],"termid":"MONDO:0030919","xrefs":{"Monarch":{"xref_id":"0030919"}}}


id: PBO:0045960
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EGFR interacting lncRNA","termid":"PBO:0045960"}


id: GO:0060110
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans.","definition_xrefs":["GOC:kmv","GOC:dph","ISSN:15518507"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cuticular extracellular matrix","termid":"GO:0060102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"basal layer of collagen and cuticulin-based cuticle extracellular matrix","synonyms":[{"name":"basal layer of collagen and cuticulin-based exoskeleton extracellular matrix","type":"related"}],"termid":"GO:0060110"}


id: GO:1904406
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:11991626"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of metabolic process","termid":"GO:0009892"},{"relation_name":"is_a","term_name":"regulation of nitric oxide metabolic process","termid":"GO:0080164"},{"relation_name":"negatively_regulates","term_name":"nitric oxide metabolic process","termid":"GO:0046209"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of nitric oxide metabolic process","synonyms":[{"name":"down regulation of nitric oxide metabolic process","type":"exact"},{"name":"down regulation of nitric oxide metabolism","type":"exact"},{"name":"down-regulation of nitric oxide metabolic process","type":"exact"},{"name":"down-regulation of nitric oxide metabolism","type":"exact"},{"name":"downregulation of nitric oxide metabolic process","type":"exact"},{"name":"downregulation of nitric oxide metabolism","type":"exact"},{"name":"inhibition of nitric oxide metabolic process","type":"narrow"},{"name":"inhibition of nitric oxide metabolism","type":"narrow"},{"name":"negative regulation of nitric oxide metabolism","type":"exact"}],"termid":"GO:1904406"}


id: MONDO:1012359
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"progressive rod-cone degeneration, non-human animal","termid":"MONDO:1011986"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progressive rod-cone degeneration, dog","secondary_identifiers":["OMIA:001298-9615"],"termid":"MONDO:1012359","xrefs":{"Monarch":{"xref_id":"1012359"}}}


id: GO:2000475
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of G protein-coupled receptor signaling pathway","termid":"GO:0045744"},{"relation_name":"is_a","term_name":"regulation of opioid receptor signaling pathway","termid":"GO:2000474"},{"relation_name":"negatively_regulates","term_name":"G protein-coupled opioid receptor signaling pathway","termid":"GO:0038003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of opioid receptor signaling pathway","synonyms":[{"name":"negative regulation of opioid receptor signalling pathway","type":"exact"}],"termid":"GO:2000475"}


id: GO:0008587
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.","definition_xrefs":["GOC:bf","GOC:mtg_sensu","ISBN:0879694238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-embryonic animal morphogenesis","termid":"GO:0009886"},{"relation_name":"part_of","term_name":"imaginal disc-derived wing morphogenesis","termid":"GO:0007476"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"imaginal disc-derived wing margin morphogenesis","synonyms":[{"name":"wing margin morphogenesis","type":"exact"}],"termid":"GO:0008587"}


id: MONDO:0016435
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete acquired dermis elastic tissue disorder with decreased elastic tissue (obsolete MONDO:0016435)","secondary_identifiers":["Orphanet:228221"],"termid":"MONDO:0016435","xrefs":{"Monarch":{"xref_id":"0016435"}}}


id: PBO:0083319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps ORF IMA3/YIL172C","termid":"PBO:0083319"}


id: PBO:0045955
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EGFLAM antisense RNA 2","termid":"PBO:0045955"}


id: PBO:0078010
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRAF interacting protein","termid":"PBO:0078010"}


id: PBO:0001534
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase Sck1","termid":"PBO:0001534"}


id: PBO:0042907
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cofilin 1 pseudogene 4","termid":"PBO:0042907"}


id: PBO:0049616
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H3 histone pseudogene 19","termid":"PBO:0049616"}


id: GO:0009942
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"embryonic axis specification","termid":"GO:0000578"},{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"part_of","term_name":"embryo development ending in seed dormancy","termid":"GO:0009793"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"longitudinal axis specification","synonyms":[{"name":"apical-basal pattern specification","type":"exact"},{"name":"longitudinal axis determination","type":"related"}],"termid":"GO:0009942"}


id: PBO:0055116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2535","termid":"PBO:0055116"}


id: MONDO:0006907
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, small, papular or nodular skin neoplasm that usually arises above the upper lip. It is characterized by an epithelial proliferation with a central cavity. The cavity wall is lined with keratinocytes.","definition_xrefs":["NCIT:C4468"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acanthoma","termid":"MONDO:0002093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"pilar sheath acanthoma","secondary_identifiers":["SCTID:254693008","UMLS:C0346005","DOID:4322","icd11.foundation:281473034","MEDGEN:83398"],"synonyms":[{"name":"Infundibuloisthmicoma","type":"exact"},{"name":"Pilar sheath acanthoma","type":"exact"},{"name":"acanthoma of Pilar sheath","type":"exact"},{"name":"acanthoma of the Pilar sheath","type":"exact"}],"termid":"MONDO:0006907","xrefs":{"Monarch":{"xref_id":"0006907"}}}


id: MONDO:0010878
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal dominant spastic paraplegia type 6 (SPG6) is a form of hereditary spastic paraplegia which usually presents in late adolescence or early adulthood as a pure phenotype of lower limb spasticity with hyperreflexia and extensor plantar responses, as well as mild bladder disturbances and pes cavus. Rarely, it can present as a complex phenotype with additional manifestations including epilepsy, variable peripheral neuropathy and/or memory impairment.","definition_xrefs":["Orphanet:100988"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary spastic paraplegia","termid":"MONDO:0019064"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"hereditary spastic paraplegia 6","secondary_identifiers":["MEDGEN:324965","MESH:C536866","SCTID:732949006","UMLS:C1838192","DOID:0110811","GARD:4928","OMIM:600363"],"synonyms":[{"name":"FSP3","type":"exact"},{"name":"NIPA1 hereditary spastic paraplegia","type":"exact"},{"name":"SPG6","type":"exact"},{"name":"autosomal dominant familial spastic paraplegia type 3","type":"exact"},{"name":"autosomal dominant spastic paraplegia 6","type":"exact"},{"name":"autosomal dominant spastic paraplegia type 6","type":"exact"},{"name":"familial spastic paraplegia autosomal dominant 3","type":"related"},{"name":"familial spastic paraplegia, autosomal dominant, 3","type":"related"},{"name":"hereditary spastic paraplegia caused by mutation in NIPA1","type":"exact"},{"name":"hereditary spastic paraplegia type 6","type":"exact"},{"name":"spastic paraplegia 6","type":"related"},{"name":"spastic paraplegia 6, autosomal dominant","type":"related"}],"termid":"MONDO:0010878","xrefs":{"Monarch":{"xref_id":"0010878"}}}


id: GO:0005851
data:
  {"annotated_genes":["SJAG_02307","SJAG_03678","SJAG_02471","SJAG_01659","SJAG_01576"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[72282,72756,74277,77813,93113],"is_not":false,"summary":null,"term":"GO:0005851"}]},"cv_name":"cellular_component","definition":"A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.","definition_xrefs":["PMID:9438375"],"direct_ancestors":[{"relation_name":"is_a","term_name":"guanyl-nucleotide exchange factor complex","termid":"GO:0032045"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"}],"gene_count":5,"genes_by_uniquename":{"SJAG_01576":null,"SJAG_01659":null,"SJAG_02307":null,"SJAG_02471":null,"SJAG_03678":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"eukaryotic translation initiation factor 2B complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"eIF-2B","type":"exact"},{"name":"eif2B","type":"exact"}],"termid":"GO:0005851","terms_by_termid":{"GO:0005851":null}}


id: GO:0004347
data:
  {"annotated_genes":["SJAG_00839"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70443],"is_not":false,"summary":null,"term":"GO:0004347"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate.","definition_xrefs":["RHEA:11816"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, interconverting aldoses and ketoses","termid":"GO:0016861"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00839":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016853"],"is_obsolete":false,"name":"glucose-6-phosphate isomerase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:PGLUCISOM-RXN","Reactome:R-HSA-70471","Reactome:R-HSA-70475","EC:5.3.1.9"],"synonyms":[{"name":"D-glucose-6-phosphate aldose-ketose-isomerase activity","type":"related"},{"name":"D-glucose-6-phosphate ketol-isomerase activity","type":"related"},{"name":"glucose phosphate isomerase activity","type":"related"},{"name":"hexose monophosphate isomerase activity","type":"broad"},{"name":"hexose phosphate isomerase activity","type":"related"},{"name":"hexosephosphate isomerase activity","type":"broad"},{"name":"oxoisomerase activity","type":"related"},{"name":"phosphoglucoisomerase activity","type":"related"},{"name":"phosphoglucose isomerase activity","type":"related"},{"name":"phosphohexoisomerase activity","type":"broad"},{"name":"phosphohexomutase activity","type":"broad"},{"name":"phosphohexose isomerase activity","type":"broad"},{"name":"phosphosaccharomutase activity","type":"broad"}],"termid":"GO:0004347","terms_by_termid":{"GO:0004347":null}}


id: MONDO:0009587
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mesoaxial hexadactyly and cardiac malformation","secondary_identifiers":["MESH:C563087","UMLS:C0796057","MEDGEN:167099","OMIM:249670"],"synonyms":[{"name":"Mexican Cardiomelic dysplasia","type":"related"},{"name":"mesoaxial hexadactyly and cardiac malformation","type":"exact"}],"termid":"MONDO:0009587","xrefs":{"Monarch":{"xref_id":"0009587"}}}


id: PBO:0082581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Chorismate mutase; catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis","termid":"PBO:0082581"}


id: PBO:0054989
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2403","termid":"PBO:0054989"}


id: PATO:0002051
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An occurrence which is relatively high.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"increased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"occurrence","termid":"PATO:0000057"},{"relation_name":"is_a","term_name":"increased process quality","termid":"PATO:0002304"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"increased occurrence","synonyms":[{"name":"increased incidence","type":"exact"}],"termid":"PATO:0002051"}


id: PBO:0067413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 524, pseudogene","termid":"PBO:0067413"}


id: MOD:01607
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-glutamic acid residue to 5-glutamyl allysine.","definition_xrefs":["PubMed:19620981","RESID:AA0504"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amidated residue","termid":"MOD:00674"},{"relation_name":"is_a","term_name":"modified L-glutamic acid residue","termid":"MOD:00906"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5-glutamyl allysine","synonyms":[{"name":"(2S)-2-([(4S)-4-amino-4-carboxybutanoyl]amino)-6-oxohexanoic acid","type":"exact"},{"name":"2-(5-glutamyl)amino-6-oxohexanoic acid","type":"exact"},{"name":"5-glutamyl allysine","type":"exact"},{"name":"N2-(gamma-glutamyl)allysine","type":"exact"},{"name":"N2-(isoglutamyl)allysine","type":"exact"},{"name":"alpha-(gamma-glutamyl)allysine","type":"exact"}],"termid":"MOD:01607"}


id: PR:P36607
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rad8 gene.","definition_xrefs":["UniProtKB:P36607","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA repair protein rad8 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC13G6.01c","synonyms":[{"name":"DNA repair protein RAD5 homolog (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-rad8","type":"exact"}],"termid":"PR:P36607"}


id: MONDO:0008289
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any porencephaly in which the cause of the disease is a mutation in the COL4A1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete COL4A1 or COL4A2-related cerebral small vessel disease with hemorrhagic tendency (obsolete MONDO:0018790)","termid":"MONDO:0018790"},{"relation_name":"is_a","term_name":"familial porencephaly","termid":"MONDO:0020496"},{"relation_name":"is_a","term_name":"COL4A1-related disorder","termid":"MONDO:0800461"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brain small vessel disease 1 with or without ocular anomalies","secondary_identifiers":["GARD:15107","UMLS:C4551998","OMIM:175780","OMIM:607595","MEDGEN:1647320","MESH:C564372","Orphanet:36383","DOID:0090125","MESH:C531642"],"synonyms":[{"name":"ADT1P","type":"exact"},{"name":"BSVD","type":"exact"},{"name":"BSVD1","type":"exact"},{"name":"COL4A1 porencephaly","type":"exact"},{"name":"COL4A1-related brain small vessel disease with haemorrhage","type":"exact"},{"name":"COL4A1-related brain small vessel disease with hemorrhage","type":"exact"},{"name":"COL4A1-related familial vascular leukoencephalopathy","type":"exact"},{"name":"COL4A1-related retinal arteriolar tortuosity-infantile hemiparesis-autosomal dominant leukoencephalopathy syndrome","type":"exact"},{"name":"POREN1","type":"related"},{"name":"T1P","type":"exact"},{"name":"autosomal dominant retinal arteriolar tortuosity, infantile hemiparesis, and leukencephalopathy","type":"exact"},{"name":"brain small vessel disease with Axenfeld-Riegar anomaly","type":"exact"},{"name":"brain small vessel disease with axenfeld-rieger anomaly","type":"exact"},{"name":"brain small vessel disease with haemorrhage","type":"exact"},{"name":"brain small vessel disease with hemorrhage","type":"exact"},{"name":"brain small vessel disease with or without ocular anomalies","type":"exact"},{"name":"hemiplegia, infantile, with porencephaly","type":"exact"},{"name":"hemiplegia, infantile, with porencephaly porencephaly, type 1","type":"related"},{"name":"infantile hemiparesis","type":"exact"},{"name":"leukoencephalopathy with axenfeld-rieger anomaly","type":"exact"},{"name":"porencephaly 1","type":"exact"},{"name":"porencephaly caused by mutation in COL4A1","type":"exact"},{"name":"porencephaly type 1","type":"exact"},{"name":"porencephaly, type 1, autosomal dominant","type":"related"},{"name":"retinal arteriolar tortuosity, infantile hemiparesis, and leukoencephalopathy, autosomal dominant","type":"exact"}],"termid":"MONDO:0008289","xrefs":{"Monarch":{"xref_id":"0008289"}}}


id: GO:1901210
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cardiac chamber formation.","definition_xrefs":["GOC:BHF","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of developmental process","termid":"GO:0050793"},{"relation_name":"regulates","term_name":"cardiac chamber formation","termid":"GO:0003207"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cardiac chamber formation","synonyms":[{"name":"regulation of heart chamber formation","type":"exact"}],"termid":"GO:1901210"}


id: PBO:0069439
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 704, pseudogene","termid":"PBO:0069439"}


id: GO:0180024
data:
  {"annotated_genes":["SJAG_05207"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[104048],"is_not":false,"summary":null,"term":"GO:0180024"}]},"cv_name":"molecular_function","definition":"An activity in which a protein, or group of proteins, acts to restrict the size of a fenestration in a membrane or membrane system (i.e. restrict the diameter of a hole in a membrane). An example of this is the molecular function is performed by ESCRT-III proteins at the nuclear envelope of fission yeast during anaphase B.","definition_xrefs":["PMID:37783794"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molecular_function","termid":"GO:0003674"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05207":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674"],"is_obsolete":false,"name":"membrane grommet activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0180024","terms_by_termid":{"GO:0180024":null}}


id: MONDO:0044252
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete skin/hair/eye pigmentation, variation in, 6 (obsolete MONDO:0044252)","secondary_identifiers":["OMIM:210750"],"synonyms":[{"name":"SHEP6","type":"related"},{"name":"skin/hair/eye pigmentation 6, Blond/Brown hair","type":"related"},{"name":"skin/hair/eye pigmentation 6, blond/brown hair","type":"exact"},{"name":"skin/hair/eye pigmentation 6, blue/Green eyes","type":"related"},{"name":"skin/hair/eye pigmentation 6, blue/green eyes","type":"exact"},{"name":"skin/hair/eye pigmentation, variation IN, 6","type":"related"}],"termid":"MONDO:0044252","xrefs":{"Monarch":{"xref_id":"0044252"}}}


id: PBO:0000346
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat protein, human WDR48 family Bun107","termid":"PBO:0000346"}


id: MONDO:1011768
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bone spavin, non-human animal","secondary_identifiers":["OMIA:001232"],"termid":"MONDO:1011768","xrefs":{"Monarch":{"xref_id":"1011768"}}}


id: PBO:0083667
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Endoplasmic reticulum packaging chaperone; required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface","termid":"PBO:0083667"}


id: MONDO:0004214
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm of the ovary characterized by the presence of cystic structures lined by endometrial-type well-differentiated cells in a fibrotic stroma.","definition_xrefs":["NCIT:C27288"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovarian endometrioid adenofibroma","termid":"MONDO:0003463"},{"relation_name":"is_a","term_name":"cystadenofibroma","termid":"MONDO:0003464"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovarian endometrioid cystadenofibroma","secondary_identifiers":["MEDGEN:233272","UMLS:C1335158","DOID:7411"],"synonyms":[{"name":"ovarian endometrioid cystadenofibroma","type":"exact"}],"termid":"MONDO:0004214","xrefs":{"Monarch":{"xref_id":"0004214"}}}


id: GO:0046752
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which viral capsid precursors are transported to a specific location in the nucleus, thus accumulating the necessary components for assembly of a capsid.","definition_xrefs":["ISBN:0781718325"],"gene_count":0,"genotype_count":0,"name":"obsolete viral capsid precursor transport to host cell nucleus (obsolete GO:0046752)","synonyms":[{"name":"establishment and maintenance of viral capsid precursor localization in nucleus","type":"broad"},{"name":"localization of viral capsid precursors in nucleus","type":"broad"},{"name":"nuclear localization of viral capsid precursors","type":"broad"},{"name":"viral capsid precursor localisation in host cell nucleus","type":"broad"},{"name":"viral capsid precursor localization in host cell nucleus","type":"broad"},{"name":"viral capsid precursor localization to host cell nucleus","type":"broad"}],"termid":"GO:0046752"}


id: FYPO:0003745
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal in the central core of the centromeric regions.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone H3 acetylation during vegetative growth","termid":"FYPO:0002363"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002494","FYPO:0002274","FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased histone H3 acetylation at centromere central core during vegetative growth","synonyms":[{"name":"increased histone H3 acetylation at centromere central core during mitotic cell cycle","type":"related"}],"termid":"FYPO:0003745"}


id: MONDO:0001694
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"interstitial keratitis","termid":"MONDO:0004902"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"diffuse interstitial keratitis","secondary_identifiers":["ICD9:370.52","MEDGEN:509780","DOID:13353","icd11.foundation:1750662534","SCTID:17157001","UMLS:C0155089"],"termid":"MONDO:0001694","xrefs":{"Monarch":{"xref_id":"0001694"}}}


id: PBO:0068344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein 115","termid":"PBO:0068344"}


id: PBO:0084162
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Highly conserved ATPase of HSP70/DnaK family; essential functional component of the EKC/KEOPS complex, with Bud32p, Cgi121p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription","termid":"PBO:0084162"}


id: FYPO:0001041
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of thiamine measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of substance in cell during vegetative growth","termid":"FYPO:0001330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased cellular thiamine level","synonyms":[{"name":"increased cellular thiamine level during mitotic cell cycle","type":"related"},{"name":"increased cellular thiamine level during vegetative growth","type":"exact"},{"name":"increased cellular vitamin B1 level","type":"exact"},{"name":"increased thiamine accumulation","type":"related"}],"termid":"FYPO:0001041"}


id: FYPO:0004725
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has one or more extensions that protrude into the cytoplasm during interphase of the mitotic cell cycle.","definition_xrefs":["PMID:15772152","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nuclear envelope morphology during vegetative growth","termid":"FYPO:0000769"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002403"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0002403","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"nuclear envelope protrusion present during mitotic interphase","synonyms":[{"name":"nuclear envelope deformation during mitotic interphase","type":"related"},{"name":"nuclear envelope protrusion present during interphase","type":"exact"},{"name":"nuclear envelope protrusion present during interphase during mitotic cell cycle","type":"related"},{"name":"nuclear envelope protrusion present during interphase during vegetative growth","type":"exact"},{"name":"protruding nuclear envelope during mitotic interphase","type":"exact"}],"termid":"FYPO:0004725"}


id: GO:0030222
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.","definition_xrefs":["GOC:add","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"granulocyte differentiation","termid":"GO:0030851"},{"relation_name":"is_a","term_name":"cell development","termid":"GO:0048468"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"eosinophil differentiation","secondary_identifiers":["GO:0035856"],"synonyms":[{"name":"eosinophil cell development","type":"related"},{"name":"eosinophil cell differentiation","type":"exact"},{"name":"eosinophil development","type":"related"}],"termid":"GO:0030222"}


id: GO:0031765
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 2 galanin receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galanin receptor binding","termid":"GO:0031763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"type 2 galanin receptor binding","synonyms":[{"name":"type 2 galanin receptor ligand","type":"narrow"}],"termid":"GO:0031765"}


id: GO:0120294
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+).","definition_xrefs":["GOC:sp","PMID:14697203"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acyltransferase activity","termid":"GO:0016410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016746","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"peptide serotonyltransferase activity","secondary_identifiers":["RHEA:66552"],"termid":"GO:0120294"}


id: GO:0043064
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum, a long thin projection from a cell, used in movement.","definition_xrefs":["ISBN:0815316194","GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete flagellum organization (obsolete GO:0043064)","synonyms":[{"name":"flagellum organisation","type":"exact"},{"name":"flagellum organization","type":"exact"},{"name":"flagellum organization and biogenesis","type":"related"}],"termid":"GO:0043064"}


id: PR:Q9US41
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- urg1 gene.","definition_xrefs":["UniProtKB:Q9US41","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uracil-regulated protein 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1002.19","synonyms":[{"name":"Spom972h-urg1","type":"exact"}],"termid":"PR:Q9US41"}


id: GO:0098750
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a FXYD domain.","definition_xrefs":["PMID:10950925","GOC:mr","PMID:18000745","GOC:dos","PMID:16403837"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein domain specific binding","termid":"GO:0019904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"FYXD domain binding","termid":"GO:0098750"}


id: PBO:0078761
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA methyltransferase subunit 11-2 pseudogene 4","termid":"PBO:0078761"}


id: GO:1990232
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex capable of phosphomannomutase activity.","definition_xrefs":["PMID:16540464","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular phosphotransferase complex","termid":"GO:1990233"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005829"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005829","GO:0005575","GO:0032991","GO:0005737"],"is_obsolete":false,"name":"phosphomannomutase complex","synonyms":[{"name":"PMM-1 complex","type":"narrow"},{"name":"PMM-1 dimer","type":"narrow"},{"name":"PMM-2 complex","type":"narrow"},{"name":"PMM-2 dimer","type":"narrow"}],"termid":"GO:1990232"}


id: PBO:0083453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CYC8","termid":"PBO:0083453"}


id: MONDO:0009259
data:
  {"annotated_genes":["SJAG_00988"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86260],"is_not":false,"summary":null,"term":"MONDO:0009259"}]},"cv_name":"mondo","definition":"Gamma-glutamylcysteine synthetase deficiency is principally characterized by hemolytic anemia, (usually rather mild), however, the presence of neurological symptoms has also been reported.","definition_xrefs":["Orphanet:33574"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited glutathione metabolism disease","termid":"MONDO:0040566"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00988":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019241"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0019241","MONDO:0005066"],"is_obsolete":false,"name":"gamma-glutamylcysteine synthetase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:270.8","OMIM:230450","MESH:C565557","DOID:0111681","MEDGEN:347272","GARD:16631","UMLS:C1856603","SCTID:36799008"],"synonyms":[{"name":"gamma-glutamylcysteine synthetase deficiency, hemolytic anaemia due to","type":"exact"},{"name":"gamma-glutamylcysteine synthetase deficiency, hemolytic anemia due to","type":"exact"},{"name":"glutamate-cysteine ligase deficiency","type":"exact"},{"name":"hemolytic anaemia due to gamma-glutamylcysteine synthetase deficiency","type":"exact"},{"name":"hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency","type":"exact"},{"name":"inborn error of glutamate-cysteine ligase activity","type":"exact"},{"name":"inborn glutamate-cysteine ligase activity disorder","type":"exact"},{"name":"rare inborn error of glutamate-cysteine ligase activity","type":"exact"}],"termid":"MONDO:0009259","terms_by_termid":{"MONDO:0009259":null},"xrefs":{"Monarch":{"xref_id":"0009259"}}}


id: FYPO:0007284
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the non-growing cell tip is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to cell tip during vegetative growth","termid":"FYPO:0001587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal protein localization to non-growing cell tip","synonyms":[{"name":"normal protein localisation to non-growing cell tip","type":"exact"},{"name":"normal protein localization to non-growing cell end","type":"exact"},{"name":"normal protein localization to non-growing cell tip during mitotic cell cycle","type":"related"},{"name":"normal protein localization to non-growing cell tip during vegetative growth","type":"exact"}],"termid":"FYPO:0007284"}


id: MONDO:0007418
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Darwinian tubercle of pinna","secondary_identifiers":["MEDGEN:343772","OMIM:124300","OMIM:124400","UMLS:C1852294"],"synonyms":[{"name":"Darwinian Notch","type":"related"},{"name":"Darwinian point of Pinna","type":"related"},{"name":"Darwinian tubercle of pinna","type":"exact"}],"termid":"MONDO:0007418","xrefs":{"Monarch":{"xref_id":"0007418"}}}


id: GO:0071625
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The behavior in which an organism produces sounds by a mechanism involving its respiratory system.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavior","termid":"GO:0007610"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"vocalization behavior","synonyms":[{"name":"vocalisation behaviour","type":"exact"}],"termid":"GO:0071625"}


id: GO:1904836
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized.","definition_xrefs":["PMID:18356247","GOC:bf","GOC:PARL","GOC:TermGenie","GO_REF:0000083","GOC:mat"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial ganglion morphogenesis","termid":"GO:0061559"},{"relation_name":"part_of","term_name":"facioacoustic ganglion development","termid":"GO:1903375"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"facioacoustic ganglion morphogenesis","synonyms":[{"name":"acoustico-facial VII-VIII ganglion complex morphogenesis","type":"exact"},{"name":"acousticofacial ganglion morphogenesis","type":"exact"},{"name":"facio-acoustic VII-VIII ganglion complex morphogenesis","type":"related"},{"name":"facio-acoustic ganglion complex VII-VIII morphogenesis","type":"exact"},{"name":"facio-acoustic ganglion complex morphogenesis","type":"related"},{"name":"facio-acoustic ganglion morphogenesis","type":"exact"}],"termid":"GO:1904836"}


id: MONDO:0013271
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"frontonasal dysplasia","termid":"MONDO:0016643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"frontonasal dysplasia - severe microphthalmia - severe facial clefting syndrome","secondary_identifiers":["MEDGEN:462056","Orphanet:306542","DOID:0081047","UMLS:C3150706","GARD:12640","OMIM:613456"],"synonyms":[{"name":"ALX1-related frontonasal dysplasia","type":"exact"},{"name":"FND3","type":"related"},{"name":"frontonasal dysplasia 3","type":"related"},{"name":"frontonasal dysplasia type 3","type":"exact"}],"termid":"MONDO:0013271","xrefs":{"Monarch":{"xref_id":"0013271"}}}


id: MONDO:0008854
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A Bardet-Biedl syndrome that has material basis in homozygous mutation in the BBS1 gene on chromosome 11q13.","definition_xrefs":["DOID:0110123","PMID:20177705"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Bardet-Biedl syndrome","termid":"MONDO:0015229"},{"relation_name":"is_a","term_name":"BBS1-related ciliopathy","termid":"MONDO:1040043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025"],"is_obsolete":false,"name":"Bardet-Biedl syndrome 1","secondary_identifiers":["MESH:C537909","OMIM:209900","GARD:820","MEDGEN:422452","UMLS:C2936862"],"synonyms":[{"name":"BBS1","type":"exact"},{"name":"Bardet-Biedl syndrome 1","type":"exact"},{"name":"Bardet-Biedl syndrome 1, modifier of","type":"exact"},{"name":"Bardet-Biedl syndrome type 1","type":"exact"}],"termid":"MONDO:0008854","xrefs":{"Monarch":{"xref_id":"0008854"}}}


id: PBO:0040145
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anti-silencing function 1B histone chaperone","termid":"PBO:0040145"}


id: MONDO:0004847
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cataract with no obvious cause occurring in persons over 50 years old.","direct_ancestors":[{"relation_name":"is_a","term_name":"cataract","termid":"MONDO:0005129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"senile cataract","secondary_identifiers":["ICD9:366.1","DOID:9669","NCIT:C35012","UMLS:C0036646","ICD9:366.10","SCTID:39450006","MEDGEN:11372"],"termid":"MONDO:0004847","xrefs":{"Monarch":{"xref_id":"0004847"}}}


id: PBO:0048981
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G-patch domain containing 4 (gene/pseudogene)","termid":"PBO:0048981"}


id: PBO:0078685
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Leu (anticodon AAG) 1-1","termid":"PBO:0078685"}


id: FYPO:0001559
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methionine import into the cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal amino acid import","termid":"FYPO:0001596"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000257","FYPO:0000138","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"normal methionine import","synonyms":[{"name":"normal L-methionine import","type":"exact"},{"name":"normal L-methionine import across plasma membrane","type":"exact"},{"name":"normal methionine import during mitotic cell cycle","type":"related"},{"name":"normal methionine import during vegetative growth","type":"exact"},{"name":"normal methionine import into cell","type":"exact"},{"name":"normal methionine uptake","type":"exact"}],"termid":"FYPO:0001559"}


id: GO:0043268
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of potassium ion transport","termid":"GO:0043266"},{"relation_name":"is_a","term_name":"positive regulation of monoatomic ion transport","termid":"GO:0043270"},{"relation_name":"positively_regulates","term_name":"potassium ion transport","termid":"GO:0006813"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"positive regulation of potassium ion transport","synonyms":[{"name":"activation of potassium ion transport","type":"narrow"},{"name":"positive regulation of K+ conductance","type":"narrow"},{"name":"positive regulation of K+ transport","type":"exact"},{"name":"positive regulation of potassium conductance","type":"narrow"},{"name":"positive regulation of potassium ion conductance","type":"narrow"},{"name":"positive regulation of potassium transport","type":"exact"},{"name":"stimulation of potassium ion transport","type":"narrow"},{"name":"up regulation of potassium ion transport","type":"exact"},{"name":"up-regulation of potassium ion transport","type":"exact"},{"name":"upregulation of potassium ion transport","type":"exact"}],"termid":"GO:0043268"}


id: PBO:0087184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase I subunit A49; essential for nucleolar assembly and for high polymerase loading rate; required for nucleolar localization of Rpa34p","termid":"PBO:0087184"}


id: PBO:0077323
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 61","termid":"PBO:0077323"}


id: PBO:0050512
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homeobox C12","termid":"PBO:0050512"}


id: PBO:0003684
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"septation protein Uds1","termid":"PBO:0003684"}


id: PBO:0083785
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential protein involved in regulation of transcription; removes Spt15p (TBP) from DNA via its C-terminal ATPase activity; may have a role in ensuring that soluble TBP is available to bind TATA-less promoters; forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity; the Mot1p-Spt15p-DNA ternary complex contains unbent DNA; coregulates transcription with Spt16p through assembly of preinitiation complex and organization of nucleosomes","termid":"PBO:0083785"}


id: PBO:0083440
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR378W","termid":"PBO:0083440"}


id: GO:0000012
data:
  {"annotated_genes":["SJAG_04410","SJAG_02680"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[77235,94043],"is_not":false,"summary":null,"term":"GO:0000012"}]},"cv_name":"biological_process","definition":"The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.","definition_xrefs":["PMID:18626472"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA repair","termid":"GO:0006281"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02680":null,"SJAG_04410":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006259","GO:0006281"],"is_obsolete":false,"name":"single strand break repair","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0000012","terms_by_termid":{"GO:0000012":null}}


id: GO:0045665
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"is_a","term_name":"regulation of neuron differentiation","termid":"GO:0045664"},{"relation_name":"negatively_regulates","term_name":"neuron differentiation","termid":"GO:0030182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of neuron differentiation","synonyms":[{"name":"down regulation of neuron differentiation","type":"exact"},{"name":"down-regulation of neuron differentiation","type":"exact"},{"name":"downregulation of neuron differentiation","type":"exact"},{"name":"inhibition of neuron differentiation","type":"narrow"}],"termid":"GO:0045665"}


id: GO:0098609
data:
  {"annotated_genes":["SJAG_01975","SJAG_00239","SJAG_00926","SJAG_04723","SJAG_03473","SJAG_01778","SJAG_04191","SJAG_00156","SJAG_04720","SJAG_00910","SJAG_02380","SJAG_03802","SJAG_03484","SJAG_01253"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70320,76926,77363,78828],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000128"},{"annotations":[103867],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036349"},{"annotations":[98900,99617],"is_not":false,"rel_names":["negatively_regulates","regulates"],"summary":null,"term":"GO:0022408"},{"annotations":[106570,103868],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:0060257"},{"annotations":[109068,108945,111682,114390,116445,106218],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1900735"}]},"cv_name":"biological_process","definition":"The attachment of one cell to another cell via adhesion molecules.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell adhesion","termid":"GO:0007155"}],"gene_count":14,"genes_by_uniquename":{"SJAG_00156":null,"SJAG_00239":null,"SJAG_00910":null,"SJAG_00926":null,"SJAG_01253":null,"SJAG_01778":null,"SJAG_01975":null,"SJAG_02380":null,"SJAG_03473":null,"SJAG_03484":null,"SJAG_03802":null,"SJAG_04191":null,"SJAG_04720":null,"SJAG_04723":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"cell-cell adhesion","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0016337"],"synonyms":[{"name":"single organismal cell-cell adhesion","type":"related"}],"termid":"GO:0098609","terms_by_termid":{"GO:0000128":null,"GO:0022408":null,"GO:0036349":null,"GO:0060257":null,"GO:1900735":null}}


id: MONDO:0008484
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Stapes ankylosis with broad thumbs and toes is a very rare genetic bone disorder characterized by ankylosis of stapes, broad thumbs and halluces, conductive hearing loss and hyperopia.","definition_xrefs":["Orphanet:140917"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NOG-related symphalangism spectrum disorder","termid":"MONDO:0100521"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"stapes ankylosis with broad thumbs and toes","secondary_identifiers":["icd11.foundation:387089262","SCTID:719305006","UMLS:C1866656","MEDGEN:357104","GARD:12631","OMIM:184460"],"synonyms":[{"name":"Teunissen-Cremers syndrome","type":"exact"},{"name":"ankylosis of stapes, hyperopia, Broad thumbs, Broad first toes, and syndactyly","type":"related"},{"name":"stapes ankylosis syndrome without symphalangism","type":"related"},{"name":"stapes ankylosis with BROAD thumb and toes","type":"related"}],"termid":"MONDO:0008484","xrefs":{"Monarch":{"xref_id":"0008484"}}}


id: PBO:0029363
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_histone_H3-K9_methylation","termid":"PBO:0029363"}


id: _global:acts_upstream_of_or_within,_negative_effect
data:
  {"annotation_feature_type":"gene","cv_name":"external","direct_ancestors":[{"relation_name":"is_a","term_name":"acts_upstream_of_or_within","termid":"_global:acts_upstream_of_or_within"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acts_upstream_of_or_within,_negative_effect","secondary_identifiers":["RO:0004033"],"termid":"_global:acts_upstream_of_or_within,_negative_effect"}


id: PBO:0043811
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CPNE2 divergent transcript","termid":"PBO:0043811"}


id: PBO:0063751
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PHB1 pseudogene 16","termid":"PBO:0063751"}


id: GO:0003074
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the rate of diuresis. Diuresis is the process of renal water excretion.","definition_xrefs":["GOC:mtg_cardio"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of diuresis (obsolete GO:0003074)","synonyms":[{"name":"regulation of diuresis","type":"exact"}],"termid":"GO:0003074"}


id: GO:0043686
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome.","definition_xrefs":["GOC:jsg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification process","termid":"GO:0036211"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"co-translational protein modification","synonyms":[{"name":"co-translational amino acid modification","type":"exact"},{"name":"co-translational modification","type":"exact"},{"name":"cotranslational amino acid modification","type":"exact"},{"name":"cotranslational modification","type":"exact"},{"name":"cotranslational protein modification","type":"exact"}],"termid":"GO:0043686"}


id: PBO:0042589
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CMT1A duplicated region transcript 2","termid":"PBO:0042589"}


id: PBO:0084570
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Membrane protein involved in zinc ion homeostasis; member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity","termid":"PBO:0084570"}


id: PBO:0090218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial phosphatidate cytidylyltransferase Tam41","termid":"PBO:0090218"}


id: GO:0018004
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The formylation of the N-terminal amino acid of proteins.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein formylation","termid":"GO:0018256"},{"relation_name":"is_a","term_name":"N-terminal protein amino acid modification","termid":"GO:0031365"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"N-terminal protein formylation","termid":"GO:0018004"}


id: GO:0034337
data:
  {"annotated_genes":["SJAG_02372","SJAG_04266","SJAG_03252","SJAG_00886","SJAG_00195"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[61196,64569,69857,114128],"is_not":false,"summary":null,"term":"GO:0034337"},{"annotations":[98804],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061818"}]},"cv_name":"biological_process","definition":"The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.","definition_xrefs":["GOC:mah","PMID:10393192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular process","termid":"GO:0009987"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00195":null,"SJAG_00886":null,"SJAG_02372":null,"SJAG_03252":null,"SJAG_04266":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"RNA folding","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"RNA chaperone","type":"related"}],"termid":"GO:0034337","terms_by_termid":{"GO:0034337":null,"GO:0061818":null}}


id: PBO:0086971
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation","termid":"PBO:0086971"}


id: PBO:0088272
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aspartic peptidase domain superfamily","termid":"PBO:0088272"}


id: MONDO:0001261
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder characterized by an electrocardiographic finding of intermittent failure of atrial electrical impulse conduction to the ventricles, characterized by a relatively constant PR interval prior to the block of an atrial impulse. (CDISC)","definition_xrefs":["NCIT:C62018"],"direct_ancestors":[{"relation_name":"is_a","term_name":"second-degree atrioventricular block","termid":"MONDO:0000467"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"Mobitz type II atrioventricular block","secondary_identifiers":["SCTID:28189009","UMLS:C0155700","DOID:11312","NANDO:2100044","ICD9:426.12","MEDGEN:102340","NANDO:2200213"],"synonyms":[{"name":"AV block second degree Mobitz type II","type":"exact"},{"name":"AV block second degree Möbitz type II","type":"exact"},{"name":"Mobitz (type) II atrioventricular block","type":"exact"},{"name":"Mobitz II","type":"exact"},{"name":"Mobitz II atrioventricular block","type":"exact"},{"name":"Mobitz type II second degree AV block","type":"exact"},{"name":"Möbitz II","type":"exact"},{"name":"Möbitz type II second degree AV block","type":"exact"},{"name":"second degree atrioventricular block Mobitz type II","type":"exact"},{"name":"second degree atrioventricular block Möbitz type II","type":"exact"},{"name":"type 2 2nd degree AV block","type":"exact"},{"name":"type 2 second degree AV block","type":"exact"},{"name":"type II second degree AV block","type":"exact"},{"name":"type II second degree atrioventricular block","type":"exact"}],"termid":"MONDO:0001261","xrefs":{"Monarch":{"xref_id":"0001261"}}}


id: SO:0001220
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An attribute describing an epigenetic process where a gene is inactivated by RNA interference.","definition_xrefs":["RSC:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"silenced","termid":"SO:0000893"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"silenced_by_RNA_interference","synonyms":[{"name":"silenced by RNA interference","type":"exact"}],"termid":"SO:0001220"}


id: PBO:0039321
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arachidonate 12-lipoxygenase, 12S type","termid":"PBO:0039321"}


id: MONDO:0010470
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Baratela-Scott syndrome (obsolete MONDO:0010470)","secondary_identifiers":["OMIM:300881"],"termid":"MONDO:0010470","xrefs":{"Monarch":{"xref_id":"0010470"}}}


id: FYPO:0001316
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of a specific substance measured in a cell is normal when the cell is in the vegetative growth phase of the life cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal level of substance in cell","termid":"FYPO:0001076"},{"relation_name":"is_a","term_name":"normal vegetative phenotype","termid":"FYPO:0001312"},{"relation_name":"is_a","term_name":"cellular physical quality phenotype during vegetative growth","termid":"FYPO:0001321"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001312","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"normal level of substance in cell during vegetative growth","synonyms":[{"name":"normal level of substance in cell during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001316"}


id: PBO:0005880
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intronic ORF","termid":"PBO:0005880"}


id: GO:0080068
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate.","definition_xrefs":["PMID:19077143"],"gene_count":0,"genotype_count":0,"name":"obsolete 5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity (obsolete GO:0080068)","termid":"GO:0080068"}


id: GO:0050027
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH.","definition_xrefs":["MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN"],"gene_count":0,"genotype_count":0,"name":"obsolete L-idonate 2-dehydrogenase activity (obsolete GO:0050027)","synonyms":[{"name":"5-keto-D-gluconate 2-reductase activity","type":"related"},{"name":"5-ketogluconate 2-reductase activity","type":"related"},{"name":"5-ketoglucono-idono-reductase activity","type":"related"},{"name":"5KGR","type":"related"},{"name":"L-idonate 2-dehydrogenase activity","type":"exact"},{"name":"L-idonate dehydrogenase activity","type":"related"},{"name":"L-idonate:NADP+ 2-oxidoreductase activity","type":"related"},{"name":"reductase, 5-ketogluconate 5- (L-idonate-forming)","type":"related"}],"termid":"GO:0050027"}


id: GO:0044777
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair.","definition_xrefs":["UniProt:P0AGE0","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"nucleoid","termid":"GO:0009295"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"single-stranded DNA-binding protein complex","synonyms":[{"name":"SSB complex","type":"exact"}],"termid":"GO:0044777"}


id: GO:0050131
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.","definition_xrefs":["EC:1.5.3.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor","termid":"GO:0016647"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"N-methyl-L-amino-acid oxidase activity","secondary_identifiers":["RHEA:11472","MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN"],"synonyms":[{"name":"N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating)","type":"related"},{"name":"N-methylamino acid oxidase activity","type":"related"}],"termid":"GO:0050131"}


id: PBO:0003375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA snR3","termid":"PBO:0003375"}


id: PBO:0001096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"methylenetetrahydrofolate reductase Met11","termid":"PBO:0001096"}


id: PR:G2TRP6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- new16 gene.","definition_xrefs":["UniProtKB:G2TRP6","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase subunit 6B-like protein new16 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC24C6.13","synonyms":[{"name":"Spom972h-new16","type":"exact"}],"termid":"PR:G2TRP6"}


id: PBO:0050393
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein A/B","termid":"PBO:0050393"}


id: PBO:0039527
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ANKRD33B pseudogene 8","termid":"PBO:0039527"}


id: SO:0001012
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A DNA sequence with catalytic activity.","definition_xrefs":["SO:cb"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"enzymatic","termid":"SO:0001185"},{"relation_name":"is_a","term_name":"oligo","termid":"SO:0000696"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAzyme","synonyms":[{"name":"DNA enzyme","type":"exact"},{"name":"catalytic DNA","type":"exact"},{"name":"deoxyribozyme","type":"related"}],"termid":"SO:0001012"}


id: PBO:0072215
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S18 pseudogene 14","termid":"PBO:0072215"}


id: PBO:0016996
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"snRNP U2 Auxiliary Factor","termid":"PBO:0016996"}


id: PBO:0040504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activator of transcription and developmental regulator AUTS2","termid":"PBO:0040504"}


id: MONDO:0015471
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare epilepsy typically characterized by isolated focal motor and somatosensory seizures. Less frequently other focal seizure types, with or without secondary generalization, have been described. The seizures usually happen when the patient is awake and take a benign course. The condition is transitory, interictal examinations are normal, and there is usually no family history of epilepsy.","definition_xrefs":["Orphanet:1544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adolescent-onset epilepsy syndrome","termid":"MONDO:0020073"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"benign focal seizures of adolescence","secondary_identifiers":["GARD:18728","SCTID:715425000","icd11.foundation:1800285392","UMLS:C4275141","MEDGEN:896830"],"synonyms":[{"name":"adolescent benign focal crisis","type":"exact"}],"termid":"MONDO:0015471","xrefs":{"Monarch":{"xref_id":"0015471"}}}


id: GO:0009910
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of flower development","termid":"GO:0009909"},{"relation_name":"is_a","term_name":"negative regulation of post-embryonic development","termid":"GO:0048581"},{"relation_name":"is_a","term_name":"negative regulation of reproductive process","termid":"GO:2000242"},{"relation_name":"negatively_regulates","term_name":"flower development","termid":"GO:0009908"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of flower development","synonyms":[{"name":"down regulation of flower development","type":"exact"},{"name":"down-regulation of flower development","type":"exact"},{"name":"downregulation of flower development","type":"exact"},{"name":"inhibition of flower development","type":"narrow"}],"termid":"GO:0009910"}


id: GO:0031398
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein ubiquitination","termid":"GO:0031396"},{"relation_name":"is_a","term_name":"positive regulation of protein modification by small protein conjugation or removal","termid":"GO:1903322"},{"relation_name":"positively_regulates","term_name":"protein ubiquitination","termid":"GO:0016567"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0070647"},{"rel_name":"positively_regulates","termid":"GO:0070647"}],"interesting_parent_ids":["GO:0070647","GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein ubiquitination","synonyms":[{"name":"activation of protein ubiquitination","type":"narrow"},{"name":"stimulation of protein ubiquitination","type":"narrow"},{"name":"up regulation of protein ubiquitination","type":"exact"},{"name":"up-regulation of protein ubiquitination","type":"exact"},{"name":"upregulation of protein ubiquitination","type":"exact"}],"termid":"GO:0031398"}


id: GO:0097261
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4.","definition_xrefs":["PMID:18647347","PMID:18184802","GOC:mw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-sulfur lyase activity","termid":"GO:0016846"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"eoxin C4 synthase activity","secondary_identifiers":["Reactome:R-HSA-2161768"],"termid":"GO:0097261"}


id: GO:0044787
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome.","definition_xrefs":["GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle DNA replication","termid":"GO:0044786"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006260"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0007049","GO:0008150","GO:0006259","GO:0006260"],"is_obsolete":false,"name":"bacterial-type DNA replication","synonyms":[{"name":"bacterial-type cell cycle DNA replication","type":"exact"}],"termid":"GO:0044787"}


id: PBO:0000041
data:
  {"annotation_feature_type":"gene","cv_name":"feature_relationshipprop_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"evidence","termid":"PBO:0000041"}


id: PBO:0084258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Inositolphosphotransferase; involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the most abundant sphingolipid; can mutate to resistance to the antifungals syringomycin E and DmAMP1 and to K. lactis zymocin","termid":"PBO:0084258"}


id: PBO:0078802
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Asn (GTT) 19-2","termid":"PBO:0078802"}


id: PBO:0064747
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase A pseudogene 83","termid":"PBO:0064747"}


id: PBO:0090924
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin conjugating enzyme E2 Ubc16","termid":"PBO:0090924"}


id: GO:0048822
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.","definition_xrefs":["GOC:devbiol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"erythrocyte development","termid":"GO:0048821"},{"relation_name":"part_of","term_name":"enucleate erythrocyte differentiation","termid":"GO:0043353"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"enucleate erythrocyte development","synonyms":[{"name":"enucleate RBC development","type":"exact"},{"name":"enucleate red blood cell development","type":"exact"}],"termid":"GO:0048822"}


id: PBO:0085829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci","termid":"PBO:0085829"}


id: PBO:0066494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ret finger protein like 4A pseudogene 5","termid":"PBO:0066494"}


id: PBO:0088286
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DUF1774 family multi-spanning conserved fungal membrane protein","termid":"PBO:0088286"}


id: GO:0008681
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-methoxy-6-(all-trans-octaprenyl)phenol + H+ + NADPH + O2 = 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + H2O + NADP+.","definition_xrefs":["PMID:4572721","PMID:27822549","RHEA:29407"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"2-octaprenyl-6-methoxyphenol hydroxylase activity","secondary_identifiers":["MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN"],"termid":"GO:0008681"}


id: PBO:0057336
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 522","termid":"PBO:0057336"}


id: PBO:0047199
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 216 member B","termid":"PBO:0047199"}


id: MOD:01841
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links either two or an L-cysteine residue and an L-serine residue by a thioether bond to form a lanthionine, either D- or L- or meso-lanthionine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-carbon thioether crosslinked residues","termid":"MOD:01993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"lanthionine","synonyms":[{"name":"2,6-diamino-4-thiaheptanedioic acid","type":"exact"},{"name":"2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid","type":"exact"},{"name":"3,3'-thiobis-(2-aminopropanoic acid)","type":"exact"},{"name":"3,3'-thiobis-L-alanine","type":"exact"},{"name":"S-(2-amino-2-carboxyethyl)-L-cysteine","type":"exact"},{"name":"bis(2-amino-2-carboxyethyl)sulfanediyl","type":"exact"},{"name":"bis(2-amino-2-carboxyethyl)sulfide","type":"exact"}],"termid":"MOD:01841"}


id: GO:0032183
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to the small ubiquitin-like protein SUMO.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ubiquitin-like protein binding","termid":"GO:0032182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"SUMO binding","synonyms":[{"name":"Smt3 binding","type":"related"},{"name":"Smt3 monomer binding","type":"narrow"}],"termid":"GO:0032183"}


id: PBO:0054712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2121","termid":"PBO:0054712"}


id: FYPO:0000353
data:
  {"alleles_by_uniquename":{"SJAG_00426:allele-1":{"allele_type":"amino_acid_mutation","description":"P363S","gene_uniquename":"SJAG_00426","name":"bbl1-P363S","uniquename":"SJAG_00426:allele-1"},"SJAG_01745:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01745","name":"lem2delta","uniquename":"SJAG_01745:allele-1"},"SJAG_01906:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01906","name":"nem1delta","uniquename":"SJAG_01906:allele-1"},"SJAG_02763:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02763","name":"ned1delta","uniquename":"SJAG_02763:allele-1"},"SJAG_02763:allele-2":{"allele_type":"amino_acid_mutation","description":"D422E,D424E","gene_uniquename":"SJAG_02763","name":"ned1cat","synonyms":[{"name":"Catalytic mutant","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-2"},"SJAG_02763:allele-4":{"allele_type":"amino_acid_mutation","description":"S235E; S651E","gene_uniquename":"SJAG_02763","name":"ned1S235E/S651E","synonyms":[{"name":"phosphomimetic","reference":"PMID:26774782","type":"exact"}],"uniquename":"SJAG_02763:allele-4"},"SJAG_02763:allele-5":{"allele_type":"amino_acid_mutation","description":"S499E; S538E; T620E; T638E; S651E","gene_uniquename":"SJAG_02763","name":"ned1-5E","uniquename":"SJAG_02763:allele-5"},"SJAG_03449:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03449","name":"man1delta","uniquename":"SJAG_03449:allele-1"},"SJAG_03449:allele-2":{"allele_type":"partial_amino_acid_deletion","description":"man1DHEH","gene_uniquename":"SJAG_03449","name":"Man1DHEH","uniquename":"SJAG_03449:allele-2"},"SJAG_03449:allele-3":{"allele_type":"amino_acid_insertion_and_deletion","description":"man1-1-488","gene_uniquename":"SJAG_03449","name":"man1-1-488","uniquename":"SJAG_03449:allele-3"},"SJAG_03940:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_03940","name":"nem2delta","uniquename":"SJAG_03940:allele-1"},"SJAG_04464:allele-1":{"allele_type":"amino_acid_mutation","description":"R152C","gene_uniquename":"SJAG_04464","name":"pim1-R152C","synonyms":[{"name":"Inferred CDK-phospho-mimic mutation","reference":"PMID:28954740","type":"exact"}],"uniquename":"SJAG_04464:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[119700,119698,119657,119693],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0003779"},{"annotations":[119480],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0006433"},{"annotations":[119520,119523,119511,119509,119508],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0001784"},{"annotations":[119510,119507,119519,119514,119506,119522],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0001556"},{"annotations":[119579],"is_not":false,"rel_names":["has_part","is_a"],"summary":null,"term":"FYPO:0003976"}]},"cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the endomembrane system is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal endomembrane system","termid":"FYPO:0002404"},{"relation_name":"output_of","term_name":"abnormal endomembrane system organization","termid":"FYPO:0000804"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00426":null,"SJAG_01745":null,"SJAG_01906":null,"SJAG_02763":null,"SJAG_03449":null,"SJAG_03940":null,"SJAG_04464":null},"genotype_count":12,"genotypes_by_uniquename":{"Man1DHEH-man1DHEH-partial_amino_acid_deletion-expression-not_assayed_or_wild_type":{"display_name":"Man1DHEH(man1DHEH)","display_uniquename":"Man1DHEH-man1DHEH-partial_amino_acid_deletion-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03449:allele-2","expression":"Not assayed or wild type"}]}]},"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"bbl1-P363S(aa)","display_uniquename":"bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00426:allele-1","expression":"Not assayed or wild type"}]}]},"lem2delta":{"display_name":"lem2delta","display_uniquename":"lem2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01745:allele-1","expression":"Null"}]}]},"man1-1-488-man1-1-488-amino_acid_insertion_and_deletion-expression-not_assayed_or_wild_type":{"display_name":"man1-1-488(aa)","display_uniquename":"man1-1-488-man1-1-488-amino_acid_insertion_and_deletion-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03449:allele-3","expression":"Not assayed or wild type"}]}]},"man1delta":{"display_name":"man1delta","display_uniquename":"man1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03449:allele-1","expression":"Null"}]}]},"ned1-5E-S499E__S538E__T620E__T638E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"ned1-5E(S499E; S538E; T620E; T638E; S651E aa)","display_uniquename":"ned1-5E-S499E__S538E__T620E__T638E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02763:allele-5","expression":"Not assayed or wild type"}]}]},"ned1S235E_S651E-S235E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"ned1S235E/S651E(S235E; S651E aa)","display_uniquename":"ned1S235E_S651E-S235E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02763:allele-4","expression":"Not assayed or wild type"}]}]},"ned1cat-D422E,D424E-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"ned1cat(D422E,D424E aa)","display_uniquename":"ned1cat-D422E,D424E-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02763:allele-2","expression":"Not assayed or wild type"}]}]},"ned1delta":{"display_name":"ned1delta","display_uniquename":"ned1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02763:allele-1","expression":"Null"}]}]},"nem1delta":{"display_name":"nem1delta","display_uniquename":"nem1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01906:allele-1","expression":"Null"}]}]},"nem2delta":{"display_name":"nem2delta","display_uniquename":"nem2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03940:allele-1","expression":"Null"}]}]},"pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"pim1-R152C(aa)","display_uniquename":"pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04464:allele-1","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"abnormal endomembrane system morphology","references_by_uniquename":{"PMID:21802294":null,"PMID:24184107":null,"PMID:25318672":null,"PMID:26774782":null,"PMID:28954740":null},"single_locus_annotated_genes":["SJAG_00426","SJAG_03449","SJAG_02763","SJAG_03940","SJAG_01745","SJAG_01906","SJAG_04464"],"single_locus_genotype_uniquenames":["man1delta","pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type","man1-1-488-man1-1-488-amino_acid_insertion_and_deletion-expression-not_assayed_or_wild_type","bbl1-P363S-P363S-amino_acid_mutation-expression-not_assayed_or_wild_type","ned1S235E_S651E-S235E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type","Man1DHEH-man1DHEH-partial_amino_acid_deletion-expression-not_assayed_or_wild_type","nem1delta","lem2delta","ned1cat-D422E,D424E-amino_acid_mutation-expression-not_assayed_or_wild_type","nem2delta","ned1delta","ned1-5E-S499E__S538E__T620E__T638E__S651E-amino_acid_mutation-expression-not_assayed_or_wild_type"],"synonyms":[{"name":"abnormal endomembrane system morphology during mitotic cell cycle","type":"related"},{"name":"abnormal endomembrane system morphology during vegetative growth","type":"exact"},{"name":"endomembrane system morphology: abnormal","type":"related"}],"termid":"FYPO:0000353","terms_by_termid":{"FYECO:0000004":null,"FYECO:0000162":null,"FYPO:0001556":null,"FYPO:0001784":null,"FYPO:0003779":null,"FYPO:0003976":null,"FYPO:0006433":null,"FYPO_EXT:0000001":null}}


id: PBO:0002274
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Brix domain protein Rpf2 (predicted)","termid":"PBO:0002274"}


id: GO:2001242
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.","definition_xrefs":["GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of intracellular signal transduction","termid":"GO:1902531"},{"relation_name":"is_a","term_name":"regulation of apoptotic signaling pathway","termid":"GO:2001233"},{"relation_name":"regulates","term_name":"intrinsic apoptotic signaling pathway","termid":"GO:0097193"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of intrinsic apoptotic signaling pathway","synonyms":[{"name":"regulation of intrinsic apoptosis","type":"narrow"},{"name":"regulation of intrinsic apoptotic pathway","type":"exact"},{"name":"regulation of intrinsic apoptotic signalling pathway","type":"exact"},{"name":"regulation of mitochondrial-mediated apoptotic pathway","type":"exact"}],"termid":"GO:2001242"}


id: GO:0180039
data:
  {"annotated_genes":["SJAG_00781","SJAG_03453","SJAG_02486","SJAG_02233","SJAG_00845","SJAG_01978"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[107450],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0180040"},{"annotations":[115890,91189,88485,104018,114929],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0062038"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of a pheromone response MAPK cascade.","definition_xrefs":["GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of MAPK cascade","termid":"GO:0043408"},{"relation_name":"regulates","term_name":"pheromone response MAPK cascade","termid":"GO:0071507"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00781":null,"SJAG_00845":null,"SJAG_01978":null,"SJAG_02233":null,"SJAG_02486":null,"SJAG_03453":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of pheromone response MAPK cascade","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0180039","terms_by_termid":{"GO:0062038":null,"GO:0180040":null}}


id: MONDO:0003296
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A morphologic variant of classic leiomyoma characterized by a dense cellular infiltrate composed of spindle or round cells with scant cytoplasm and a less obvious interlacing fascicle pattern.","definition_xrefs":["NCIT:C4256"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leiomyoma","termid":"MONDO:0001572"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cellular leiomyoma","secondary_identifiers":["DOID:5139","ICDO:8892/0","UMLS:C0334477","MEDGEN:83155"],"synonyms":[{"name":"cellular leiomyoma","type":"exact"},{"name":"cellular leiomyoma (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0003296","xrefs":{"Monarch":{"xref_id":"0003296"}}}


id: GO:1900240
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular process","termid":"GO:0048523"},{"relation_name":"is_a","term_name":"regulation of phenotypic switching","termid":"GO:1900239"},{"relation_name":"negatively_regulates","term_name":"phenotypic switching","termid":"GO:0036166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of phenotypic switching","synonyms":[{"name":"down regulation of phenotypic dimorphism","type":"related"},{"name":"down regulation of phenotypic switching","type":"exact"},{"name":"down-regulation of phenotypic dimorphism","type":"related"},{"name":"down-regulation of phenotypic switching","type":"exact"},{"name":"downregulation of phenotypic dimorphism","type":"related"},{"name":"downregulation of phenotypic switching","type":"exact"},{"name":"inhibition of phenotypic dimorphism","type":"related"},{"name":"inhibition of phenotypic switching","type":"narrow"},{"name":"negative regulation of phenotypic dimorphism","type":"related"}],"termid":"GO:1900240"}


id: GO:1990748
data:
  {"annotated_genes":["SJAG_04608","SJAG_03653","SJAG_01995","SJAG_02973","SJAG_00614","SJAG_03288","SJAG_00365","SJAG_04674","SJAG_04063","SJAG_03316","SJAG_01973","SJAG_05181","SJAG_02247","SJAG_00988","SJAG_02276","SJAG_01344","SJAG_00419","SJAG_03166","SJAG_03303","SJAG_02960","SJAG_01404","SJAG_00668","SJAG_04726","SJAG_04125","SJAG_01351","SJAG_02630","SJAG_01628","SJAG_02988","SJAG_04632","SJAG_01596","SJAG_06611","SJAG_02907","SJAG_04516","SJAG_02010","SJAG_05256","SJAG_00489","SJAG_01651","SJAG_03476","SJAG_01457","SJAG_01162","SJAG_00219","SJAG_00141","SJAG_03623","SJAG_03108","SJAG_01612","SJAG_04399","SJAG_04403","SJAG_01216","SJAG_04242","SJAG_00179","SJAG_02515","SJAG_00270","SJAG_03494","SJAG_04404","SJAG_01199","SJAG_04953","SJAG_00903","SJAG_02599","SJAG_01734","SJAG_03497","SJAG_04788","SJAG_03797","SJAG_02106","SJAG_04823"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88314,88319,88416,90454,92785,93469,93470,95021,95291,97431,98692,99338,99525,100167,100643,103105,103178,103933,109027,112595,113317,113769,113807,114904,115005,118480,118901,119042],"is_not":false,"summary":null,"term":"GO:1990748"},{"annotations":[113039],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110095"},{"annotations":[97380,108742,118505,97342,93652,71183],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098849"},{"annotations":[114046],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140114"},{"annotations":[95531,118591,105365,117669,109144,100322],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061692"},{"annotations":[105368],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140041"},{"annotations":[102535,87748],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070458"},{"annotations":[57588,65607,63727,69054,68474,107111],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098869"},{"annotations":[78503,95868],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0046294"},{"annotations":[99597,69223,89323,89745,93480,58084,61027,74668,65296],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019430"},{"annotations":[106921,95899,100326],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0110052"}]},"cv_name":"biological_process","definition":"Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.","definition_xrefs":["GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular process","termid":"GO:0009987"},{"relation_name":"is_a","term_name":"detoxification","termid":"GO:0098754"},{"relation_name":"part_of","term_name":"cellular response to toxic substance","termid":"GO:0097237"}],"gene_count":64,"genes_by_uniquename":{"SJAG_00141":null,"SJAG_00179":null,"SJAG_00219":null,"SJAG_00270":null,"SJAG_00365":null,"SJAG_00419":null,"SJAG_00489":null,"SJAG_00614":null,"SJAG_00668":null,"SJAG_00903":null,"SJAG_00988":null,"SJAG_01162":null,"SJAG_01199":null,"SJAG_01216":null,"SJAG_01344":null,"SJAG_01351":null,"SJAG_01404":null,"SJAG_01457":null,"SJAG_01596":null,"SJAG_01612":null,"SJAG_01628":null,"SJAG_01651":null,"SJAG_01734":null,"SJAG_01973":null,"SJAG_01995":null,"SJAG_02010":null,"SJAG_02106":null,"SJAG_02247":null,"SJAG_02276":null,"SJAG_02515":null,"SJAG_02599":null,"SJAG_02630":null,"SJAG_02907":null,"SJAG_02960":null,"SJAG_02973":null,"SJAG_02988":null,"SJAG_03108":null,"SJAG_03166":null,"SJAG_03288":null,"SJAG_03303":null,"SJAG_03316":null,"SJAG_03476":null,"SJAG_03494":null,"SJAG_03497":null,"SJAG_03623":null,"SJAG_03653":null,"SJAG_03797":null,"SJAG_04063":null,"SJAG_04125":null,"SJAG_04242":null,"SJAG_04399":null,"SJAG_04403":null,"SJAG_04404":null,"SJAG_04516":null,"SJAG_04608":null,"SJAG_04632":null,"SJAG_04674":null,"SJAG_04726":null,"SJAG_04788":null,"SJAG_04823":null,"SJAG_04953":null,"SJAG_05181":null,"SJAG_05256":null,"SJAG_06611":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098754"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0098754","GO:0008150"],"is_obsolete":false,"name":"cellular detoxification","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"termid":"GO:1990748","terms_by_termid":{"GO:0019430":null,"GO:0046294":null,"GO:0061692":null,"GO:0070458":null,"GO:0098849":null,"GO:0098869":null,"GO:0110052":null,"GO:0110095":null,"GO:0140041":null,"GO:0140114":null,"GO:1990748":null}}


id: MONDO:0003527
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A rare genetic neoplastic disorder with an autosomal dominant pattern of inheritance characterized by multiple, recurrent skin cancers that spontaneously resolve. It has been described almost exclusively in families of Scottish origin. It is caused by a mutation in the tumor-suppressing gene, TGFBR1, on chromosome 9. Clinical presentation is usually rapidly growing squamous cell carcinomas or keratoacanthomas that primarily localize to sun-exposed areas. Appearance of the neoplasms occurs over several weeks before receding over the course of several months if untreated. The regression of the lesions leaves pitting cicatrices but no other known sequelae.","gene_count":0,"genotype_count":0,"name":"obsolete Ferguson-Smith tumor (obsolete MONDO:0003527)","termid":"MONDO:0003527","xrefs":{"Monarch":{"xref_id":"0003527"}}}


id: GO:0051229
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The controlled breakdown of the spindle during a meiotic cell cycle.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meiotic spindle organization","termid":"GO:0000212"},{"relation_name":"is_a","term_name":"spindle disassembly","termid":"GO:0051230"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007010"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0000226"},{"rel_name":"part_of","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0000226","GO:0007010","GO:0007049","GO:0008150"],"is_obsolete":false,"name":"meiotic spindle disassembly","synonyms":[{"name":"meiotic spindle breakdown","type":"exact"},{"name":"meiotic spindle catabolism","type":"exact"},{"name":"meiotic spindle degradation","type":"exact"},{"name":"spindle breakdown during meiosis","type":"exact"},{"name":"spindle degradation during meiosis","type":"exact"},{"name":"spindle disassembly during meiosis","type":"exact"}],"termid":"GO:0051229"}


id: PBO:0036350
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.1.1.181","termid":"PBO:0036350"}


id: MONDO:0009107
data:
  {"annotated_genes":["SJAG_01941","SJAG_02463"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87145,87146],"is_not":false,"summary":null,"term":"MONDO:0009107"}]},"cv_name":"mondo","definition":"Diastrophic dwarfism is a rare disorder marked by short stature with short extremities (final adult height is 120cm +/- 10cm), and joint malformations leading to multiple joint contractures (principally involving the shoulders, elbows, interphalangeal joints and hips).","definition_xrefs":["Orphanet:628"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with micromelia (obsolete MONDO:0018232)","termid":"MONDO:0018232"},{"relation_name":"is_a","term_name":"mineral metabolism disease","termid":"MONDO:0000226"},{"relation_name":"is_a","term_name":"osteochondrodysplasia","termid":"MONDO:0005516"},{"relation_name":"is_a","term_name":"inborn errors of metabolism","termid":"MONDO:0019052"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01941":null,"SJAG_02463":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005497","MONDO:0005066"],"is_obsolete":false,"name":"diastrophic dysplasia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C156311","icd11.foundation:1681550532","ICD9:756.89","NORD:1051","ICD10CM:Q77.5","MEDGEN:113103","OMIM:222600","SCTID:58561002","UMLS:C0220726","GARD:6275","MESH:C536170","DOID:14687"],"synonyms":[{"name":"DD","type":"related"},{"name":"DTD","type":"related"},{"name":"diastrophic dwarfism","type":"related"},{"name":"diastrophic dysplasia","type":"exact"},{"name":"diastrophic dysplasia, Broad bone-Platyspondylic variant","type":"related"}],"termid":"MONDO:0009107","terms_by_termid":{"MONDO:0009107":null},"xrefs":{"Monarch":{"xref_id":"0009107"}}}


id: GO:0106069
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase.","definition_xrefs":["PMID:16847351"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SUMO ligase complex","termid":"GO:0106068"},{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"},{"relation_name":"part_of","term_name":"condensed nuclear chromosome","termid":"GO:0000794"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005694","GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"synapsis initiation complex","termid":"GO:0106069"}


id: GO:0061596
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.","definition_xrefs":["GOC:dph","PMID:24463506","EC:1.1.1.373"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"3-sulfolactaldehyde reductase activity","secondary_identifiers":["MetaCyc:RXN-15299","RHEA:40511"],"termid":"GO:0061596"}


id: MONDO:0001582
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"ectropion","termid":"MONDO:0002043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cicatricial ectropion","secondary_identifiers":["MEDGEN:102327","SCTID:28914006","ICD9:374.14","UMLS:C0155196","DOID:12782"],"termid":"MONDO:0001582","xrefs":{"Monarch":{"xref_id":"0001582"}}}


id: PBO:0027922
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_localization_to_cell-cell_contact_point_during_conjugation","termid":"PBO:0027922"}


id: PR:O14182
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 30S ribosomal protein S12 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01115","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"37S ribosomal protein S12, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4F8.06","secondary_identifiers":["UniProtKB:O14182"],"synonyms":[{"name":"Spom972h-rpsL","type":"exact"}],"termid":"PR:O14182"}


id: PBO:0048401
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GAS6 antisense RNA 1","termid":"PBO:0048401"}


id: GO:0061507
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.","definition_xrefs":["GOC:dph","PMID:23258412","PMID:23910378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenyl ribonucleotide binding","termid":"GO:0032559"},{"relation_name":"is_a","term_name":"guanyl ribonucleotide binding","termid":"GO:0032561"},{"relation_name":"is_a","term_name":"anion binding","termid":"GO:0043168"},{"relation_name":"is_a","term_name":"cyclic GMP-AMP binding","termid":"GO:0140702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"2',3'-cyclic GMP-AMP binding","secondary_identifiers":["GO:0098546"],"synonyms":[{"name":"2',3' cGAMP binding","type":"exact"},{"name":"2',3' cyclic GAMP binding","type":"exact"},{"name":"2',3'-cGAMP binding","type":"exact"},{"name":"2',3'-cyclic GAMP binding","type":"exact"},{"name":"2',5-3',5'-cyclic GMP-AMP binding","type":"exact"},{"name":"c[G(2',5')pA(3',5')p] binding","type":"exact"},{"name":"cyclic-GMP-AMP binding","type":"broad"}],"termid":"GO:0061507"}


id: PBO:0050585
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heparan sulfate 6-O-sulfotransferase 2","termid":"PBO:0050585"}


id: MONDO:0000136
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Keratosis follicularis spinulosa decalvans is a rare genodermatosis occurring during infancy or childhood, predominantly affecting males, and characterized by diffuse follicular hyperkeratosis associated with progressive cicatricial alopecia of the scalp, eyebrows and eyelashes. Additional findings can include photophobia, corneal dystrophy, facial erythema, and/or palmoplantar keratoderma.","definition_xrefs":["Orphanet:2340"],"direct_ancestors":[{"relation_name":"is_a","term_name":"keratosis","termid":"MONDO:0006566"},{"relation_name":"is_a","term_name":"keratosis pilaris atrophicans","termid":"MONDO:0018855"},{"relation_name":"is_a","term_name":"disorder of polyamine metabolism","termid":"MONDO:0800159"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066"],"is_obsolete":false,"name":"keratosis follicularis spinulosa decalvans","secondary_identifiers":["MEDGEN:83355","UMLS:C0343057","DOID:0080753","GARD:6829","icd11.foundation:303213910","ICD9:757.39","NORD:1288","SCTID:238626006"],"synonyms":[{"name":"keratosis pilaris decalvans","type":"exact"}],"termid":"MONDO:0000136","xrefs":{"Monarch":{"xref_id":"0000136"}}}


id: GO:0097140
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.","definition_xrefs":["PMID:14634621","GOC:so"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Bcl-2 family protein complex","termid":"GO:0097136"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"BIM-BCL-xl complex","termid":"GO:0097140"}


id: PBO:0053168
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lymphoid enhancer binding factor 1","termid":"PBO:0053168"}


id: PBO:0045342
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"docking protein 2","termid":"PBO:0045342"}


id: PBO:0064510
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase II subunit J2","termid":"PBO:0064510"}


id: GO:0004565
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.","definition_xrefs":["EC:3.2.1.23"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactosidase activity","termid":"GO:0015925"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0016798","GO:0016787","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"beta-galactosidase activity","secondary_identifiers":["Reactome:R-HSA-1630306","Reactome:R-HSA-1605624","Reactome:R-HSA-1606312","Reactome:R-HSA-2265534","Reactome:R-HSA-2090079","Reactome:R-HSA-9036061","MetaCyc:3.2.1.23-RXN","Reactome:R-HSA-9840795","Reactome:R-HSA-1793217"],"synonyms":[{"name":"beta-D-galactanase activity","type":"related"},{"name":"beta-D-galactoside galactohydrolase activity","type":"related"},{"name":"beta-D-lactosidase activity","type":"related"},{"name":"beta-lactosidase activity","type":"related"},{"name":"exo-(1->4)-beta-D-galactanase activity","type":"related"},{"name":"hydrolact","type":"related"}],"termid":"GO:0004565"}


id: MONDO:1010764
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Vitiligo that occurs in chicken.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bird disease","termid":"MONDO:0024905"},{"relation_name":"is_a","term_name":"vitiligo, non-human animal","termid":"MONDO:1010136"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vitiligo, chicken","secondary_identifiers":["OMIA:001055-9031"],"termid":"MONDO:1010764","xrefs":{"Monarch":{"xref_id":"1010764"}}}


id: GO:0072763
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular response to amine stimulus","termid":"GO:0071418"},{"relation_name":"is_a","term_name":"response to hesperadin","termid":"GO:1901595"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to hesperadin","termid":"GO:0072763"}


id: PBO:0045888
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 gamma","termid":"PBO:0045888"}


id: PBO:0079541
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin like modifier activating enzyme 2","termid":"PBO:0079541"}


id: MONDO:0008074
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete nerve growth factor, alpha subunit (obsolete MONDO:0008074)","secondary_identifiers":["OMIM:162020"],"synonyms":[{"name":"NGFA","type":"exact"},{"name":"nerve growth factor, ALPHA SUBUNIT","type":"exact"},{"name":"nerve growth factor, alpha subunit","type":"exact"}],"termid":"MONDO:0008074","xrefs":{"Monarch":{"xref_id":"0008074"}}}


id: MONDO:0044302
data:
  {"annotated_genes":["SJAG_03967"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87226],"is_not":false,"summary":null,"term":"MONDO:0044302"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03967":null},"genotype_count":0,"is_obsolete":false,"name":"congenital heart defects, dysmorphic facial features, and intellectual developmental disorder","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:646278","MEDGEN:1385307","UMLS:C4479246","DOID:0112247","OMIM:617360"],"synonyms":[{"name":"CDK13-related congenital heart defects-intellectual disability-facial dysmorphism syndrome","type":"exact"},{"name":"CHDFIDD","type":"related"},{"name":"congenital heart defects, dysmorphic FACIAL features, and intellectual developmental disorder","type":"related"}],"termid":"MONDO:0044302","terms_by_termid":{"MONDO:0044302":null},"xrefs":{"Monarch":{"xref_id":"0044302"}}}


id: GO:1903865
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex which is capable of sigma factor antagonist activity.","definition_xrefs":["GOC:bhm","GOC:TermGenie","PMID:23687042","GO_REF:0000088"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription regulator complex","termid":"GO:0005667"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"sigma factor antagonist complex","termid":"GO:1903865"}


id: GO:0032212
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of telomere maintenance via telomerase","termid":"GO:0032210"},{"relation_name":"is_a","term_name":"positive regulation of telomere maintenance via telomere lengthening","termid":"GO:1904358"},{"relation_name":"is_a","term_name":"positive regulation of DNA biosynthetic process","termid":"GO:2000573"},{"relation_name":"positively_regulates","term_name":"telomere maintenance via telomerase","termid":"GO:0007004"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0032200"},{"rel_name":"positively_regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"positively_regulates","termid":"GO:0032200"}],"interesting_parent_ids":["GO:0006259","GO:0032200","GO:0008150"],"is_obsolete":false,"name":"positive regulation of telomere maintenance via telomerase","synonyms":[{"name":"activation of telomere maintenance via telomerase","type":"narrow"},{"name":"stimulation of telomere maintenance via telomerase","type":"narrow"},{"name":"up regulation of telomere maintenance via telomerase activity","type":"exact"},{"name":"up-regulation of telomere maintenance via telomerase activity","type":"exact"},{"name":"upregulation of telomere maintenance via telomerase activity","type":"exact"}],"termid":"GO:0032212"}


id: PBO:0017819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved eukaryotic protein Hgh1","termid":"PBO:0017819"}


id: MONDO:1011603
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Type 2 diabetes mellitus that occurs in crab-eating macaque.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"type 2 diabetes mellitus, non-human animal","termid":"MONDO:1011402"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"type 2 diabetes mellitus, crab-eating macaque","secondary_identifiers":["OMIA:000284-9541"],"termid":"MONDO:1011603","xrefs":{"Monarch":{"xref_id":"1011603"}}}


id: MONDO:0024550
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any frontometaphyseal dysplasia in which the cause of the disease is a mutation in the FLNA gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"frontometaphyseal dysplasia","termid":"MONDO:0015942"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"frontometaphyseal dysplasia 1","secondary_identifiers":["DOID:0111786","GARD:15293","MEDGEN:923943","UMLS:C4281559","OMIM:305620"],"synonyms":[{"name":"FLNA frontometaphyseal dysplasia","type":"exact"},{"name":"FMD1","type":"related"},{"name":"FRONTOMETAPHYSEAL dysplasia 1","type":"related"},{"name":"Fmd","type":"related"},{"name":"frontometaphyseal dysplasia 1, X-linked recessive","type":"exact"},{"name":"frontometaphyseal dysplasia caused by mutation in FLNA","type":"exact"}],"termid":"MONDO:0024550","xrefs":{"Monarch":{"xref_id":"0024550"}}}


id: PBO:0069832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1118, pseudogene","termid":"PBO:0069832"}


id: RO:0002162
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.","direct_ancestors":[{"relation_name":"is_a","term_name":"evolutionarily_related_to","termid":"RO:0002320"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in_taxon","termid":"RO:0002162"}


id: GO:0071105
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.","definition_xrefs":["GOC:mah","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to cytokine","termid":"GO:0034097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to interleukin-11","synonyms":[{"name":"response to IL-11","type":"exact"}],"termid":"GO:0071105"}


id: GO:1904898
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:15358192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of fibroblast proliferation","termid":"GO:0048147"},{"relation_name":"is_a","term_name":"regulation of hepatic stellate cell proliferation","termid":"GO:1904897"},{"relation_name":"negatively_regulates","term_name":"hepatic stellate cell proliferation","termid":"GO:1990922"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of hepatic stellate cell proliferation","synonyms":[{"name":"down regulation of Ito cell proliferation","type":"exact"},{"name":"down regulation of hepatic perisinusoidal cell proliferation","type":"exact"},{"name":"down regulation of hepatic stellate cell proliferation","type":"exact"},{"name":"down regulation of perisinusoidal cell proliferation","type":"exact"},{"name":"down-regulation of Ito cell proliferation","type":"exact"},{"name":"down-regulation of hepatic perisinusoidal cell proliferation","type":"exact"},{"name":"down-regulation of hepatic stellate cell proliferation","type":"exact"},{"name":"down-regulation of perisinusoidal cell proliferation","type":"exact"},{"name":"downregulation of Ito cell proliferation","type":"exact"},{"name":"downregulation of hepatic perisinusoidal cell proliferation","type":"exact"},{"name":"downregulation of hepatic stellate cell proliferation","type":"exact"},{"name":"downregulation of perisinusoidal cell proliferation","type":"exact"},{"name":"inhibition of Ito cell proliferation","type":"narrow"},{"name":"inhibition of hepatic perisinusoidal cell proliferation","type":"narrow"},{"name":"inhibition of hepatic stellate cell proliferation","type":"narrow"},{"name":"inhibition of perisinusoidal cell proliferation","type":"narrow"},{"name":"negative regulation of Ito cell proliferation","type":"exact"},{"name":"negative regulation of hepatic perisinusoidal cell proliferation","type":"exact"},{"name":"negative regulation of perisinusoidal cell proliferation","type":"exact"}],"termid":"GO:1904898"}


id: PBO:0046780
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EYA transcriptional coactivator and phosphatase 1","termid":"PBO:0046780"}


id: RO:0002622
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"visits","termid":"RO:0002618"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"visits_flowers_of","termid":"RO:0002622"}


id: PBO:0058209
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4501","termid":"PBO:0058209"}


id: SO:0001254
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A kind of chromosome variation where the chromosome complement is an exact multiple of the haploid number and is greater than the diploid number.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome_number_variation","termid":"SO:1000182"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polyploid","secondary_identifiers":["http://en.wikipedia.org/wiki/Polyploid"],"termid":"SO:0001254"}


id: GO:0032188
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete establishment of actomyosin contractile ring localization (obsolete GO:0032188)","synonyms":[{"name":"actomyosin ring positioning","type":"related"},{"name":"contractile ring positioning","type":"broad"},{"name":"cytokinesis site selection by contractile ring positioning","type":"exact"},{"name":"establishment of contractile ring localisation involved in cell cycle cytokinesis","type":"exact"},{"name":"establishment of contractile ring localization involved in cell cycle cytokinesis","type":"exact"},{"name":"establishment of contractile ring localization involved in cytokinesis during cell cycle","type":"related"}],"termid":"GO:0032188"}


id: PBO:0002832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Astra associated protein 1 Asa1","termid":"PBO:0002832"}


id: PBO:0085251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Peripherally bound inner membrane protein of the mitochondrial matrix; involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p","termid":"PBO:0085251"}


id: PBO:0004937
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1,3-beta-glucan synthase regulatory factor Chf3/Chr4","termid":"PBO:0004937"}


id: PBO:0011141
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IMPACT domain protein, inmplicated in translation (predicted)","termid":"PBO:0011141"}


id: MONDO:0014909
data:
  {"annotated_genes":["SJAG_03794"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87554],"is_not":false,"summary":null,"term":"MONDO:0014909"}]},"cv_name":"mondo","definition":"Any primary ciliary dyskinesia in which the cause of the disease is a mutation in the DNAJB13 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary ciliary dyskinesia","termid":"MONDO:0016575"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03794":null},"genotype_count":0,"is_obsolete":false,"name":"primary ciliary dyskinesia 34","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0110610","GARD:16187","OMIM:617091","MEDGEN:934689","UMLS:C4310722"],"synonyms":[{"name":"CILD34","type":"exact"},{"name":"DNAJB13 primary ciliary dyskinesia","type":"exact"},{"name":"ciliary dyskinesia, primary, 34","type":"exact"},{"name":"ciliary dyskinesia, primary, 34, without situs inversus","type":"related"},{"name":"ciliary dyskinesia, primary, type 34","type":"exact"},{"name":"primary ciliary dyskinesia 34 without situs inversus","type":"exact"},{"name":"primary ciliary dyskinesia caused by mutation in DNAJB13","type":"exact"},{"name":"primary ciliary dyskinesia type 34","type":"exact"}],"termid":"MONDO:0014909","terms_by_termid":{"MONDO:0014909":null},"xrefs":{"Monarch":{"xref_id":"0014909"}}}


id: PBO:0085268
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Peroxisomal acyl-CoA thioesterase; likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids","termid":"PBO:0085268"}


id: PR:Q9P332
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of any of the following genes in Schizosaccharomyces pombe 972h-: SPAC750.04c/SPAC977.02.","definition_xrefs":["PRO:DNx","UniProtKB:Q9P332"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UPF0742 protein C750.04c/C977.02 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC977.02","synonyms":[{"name":"Spom972h-SPAC977.02","type":"exact"}],"termid":"PR:Q9P332"}


id: MONDO:0020715
data:
  {"annotated_genes":["SJAG_06603"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87658],"is_not":false,"summary":null,"term":"MONDO:0020715"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":1,"genes_by_uniquename":{"SJAG_06603":null},"genotype_count":0,"is_obsolete":false,"name":"multiple system atrophy 1, susceptibility to","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:811503","OMIM:146500","UMLS:C3714927"],"synonyms":[{"name":"MSA1","type":"exact"},{"name":"MSA1, susceptibility to","type":"exact"},{"name":"multiple system atrophy 1, susceptibility to","type":"exact"},{"name":"multiple system atrophy, susceptibility to","type":"exact"}],"termid":"MONDO:0020715","terms_by_termid":{"MONDO:0020715":null},"xrefs":{"Monarch":{"xref_id":"0020715"}}}


id: GO:0031529
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.","definition_xrefs":["GOC:mah","PMID:10036235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane bounded cell projection organization","termid":"GO:0120036"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ruffle organization","synonyms":[{"name":"ruffle organisation","type":"exact"},{"name":"ruffle organization and biogenesis","type":"related"}],"termid":"GO:0031529"}


id: PBO:0085053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-essential protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation; ECM13 has a paralog, YJR115W, that arose from the whole genome duplication","termid":"PBO:0085053"}


id: PBO:0059696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO2 pseudogene 4","termid":"PBO:0059696"}


id: GO:1900070
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response.","definition_xrefs":["GOC:dgf","PMID:16278455","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular process","termid":"GO:0048523"},{"relation_name":"is_a","term_name":"regulation of cellular hyperosmotic salinity response","termid":"GO:1900069"},{"relation_name":"is_a","term_name":"negative regulation of response to salt stress","termid":"GO:1901001"},{"relation_name":"negatively_regulates","term_name":"cellular hyperosmotic salinity response","termid":"GO:0071475"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cellular hyperosmotic salinity response","synonyms":[{"name":"down regulation of cellular hyperosmotic salinity response","type":"related"},{"name":"down regulation of cellular response to hyperosmotic salt stress","type":"exact"},{"name":"down-regulation of cellular hyperosmotic salinity response","type":"related"},{"name":"down-regulation of cellular response to hyperosmotic salt stress","type":"exact"},{"name":"downregulation of cellular hyperosmotic salinity response","type":"related"},{"name":"downregulation of cellular response to hyperosmotic salt stress","type":"exact"},{"name":"inhibition of cellular hyperosmotic salinity response","type":"narrow"},{"name":"inhibition of cellular response to hyperosmotic salt stress","type":"narrow"},{"name":"negative regulation of cellular response to hyperosmotic salt stress","type":"exact"}],"termid":"GO:1900070"}


id: MONDO:0010496
data:
  {"annotated_genes":["SJAG_00992"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85660],"is_not":false,"summary":null,"term":"MONDO:0010496"}]},"cv_name":"mondo","definition":"X-linked intellectual disability-short stature-overweight syndrome is a multiple congenital anomalies syndrome characterized by borderline to severe intellectual disability, speech delay, short stature, elevated body mass index, a pattern of truncal obesity (reported in older males), and variable neurologic features (e.g. hypotonia, tremors, gait disturbances, behavioral problems, and seizure disorders). Less common manifestations include microcephaly, microorchidism and/or microphallus. Dysmorphic features have been reported in some patients but no consistent pattern has been noted.","definition_xrefs":["Orphanet:457240"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00992":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"X-linked intellectual disability-short stature-overweight syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0796218","DOID:0112056","GARD:17800","MEDGEN:901885","OMIM:300957"],"synonyms":[{"name":"MRX12","type":"related"},{"name":"intellectual developmental disorder, X-linked 12, X-linked recessive","type":"exact"},{"name":"intellectual disability, X-linked 12","type":"related"},{"name":"intellectual disability, X-linked 35","type":"related"},{"name":"intellectual disability, X-linked type 12","type":"exact"},{"name":"mental retardation, X-linked 12","type":"related"},{"name":"mental retardation, X-linked 35","type":"related"},{"name":"mental retardation, X-linked type 12","type":"exact"}],"termid":"MONDO:0010496","terms_by_termid":{"MONDO:0010496":null},"xrefs":{"Monarch":{"xref_id":"0010496"}}}


id: FYPO:0007718
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which SMN complex assembly is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein-containing complex assembly","termid":"FYPO:0000447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"abnormal SMN complex assembly","synonyms":[{"name":"abnormal SMN complex assembly during mitotic cell cycle","type":"related"},{"name":"abnormal SMN complex assembly during vegetative growth","type":"exact"}],"termid":"FYPO:0007718"}


id: FYPO:0005021
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the actomyosin contractile ring for a shorter time than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased duration of protein localization to cell division site","termid":"FYPO:0002528"},{"relation_name":"is_a","term_name":"abnormal protein localization to actomyosin contractile ring","termid":"FYPO:0002560"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0000032","FYPO:0005447","FYPO:0000138","FYPO:0000631","FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased duration of protein localization to actomyosin contractile ring","synonyms":[{"name":"decreased duration of protein localisation to actomyosin contractile ring","type":"exact"},{"name":"decreased duration of protein localization to actomyosin contractile ring during mitotic cell cycle","type":"related"},{"name":"decreased duration of protein localization to actomyosin contractile ring during vegetative growth","type":"exact"},{"name":"decreased duration of protein localization to actomyosin contractile ring involved in mitotic cytokinesis","type":"exact"},{"name":"decreased duration of protein localization to cytokinetic contractile ring","type":"exact"},{"name":"decreased duration of protein localization to mitotic contractile ring","type":"exact"},{"name":"decreased duration of protein recruitment to actomyosin contractile ring","type":"related"},{"name":"reduced duration of protein localization to actomyosin contractile ring","type":"exact"}],"termid":"FYPO:0005021"}


id: MONDO:1011663
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"digestive system disorder, non-human animal","termid":"MONDO:1011311"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"displaced abomasum, non-human animal","secondary_identifiers":["OMIA:001119"],"termid":"MONDO:1011663","xrefs":{"Monarch":{"xref_id":"1011663"}}}


id: MONDO:0005384
data:
  {"annotated_genes":["SJAG_02765","SJAG_00824","SJAG_01184"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85723],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024556"},{"annotations":[87489],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014924"},{"annotations":[87488],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014925"}]},"cv_name":"mondo","definition":"A seizure caused by a localized disorder.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epilepsy","termid":"MONDO:0005027"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00824":null,"SJAG_01184":null,"SJAG_02765":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"focal epilepsy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD9:345.50","NCIT:C122812","SCTID:230381009","MEDGEN:41836","EFO:0004263","MESH:D004828","UMLS:C0014547","DOID:2234"],"synonyms":[{"name":"focal epilepsy","type":"exact"},{"name":"localisation-related epilepsy","type":"exact"},{"name":"partial epilepsy","type":"exact"}],"termid":"MONDO:0005384","terms_by_termid":{"MONDO:0014924":null,"MONDO:0014925":null,"MONDO:0024556":null},"xrefs":{"Monarch":{"xref_id":"0005384"}}}


id: PBO:0036049
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_sodium_chloride","termid":"PBO:0036049"}


id: PBO:0051530
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"interleukin 2 receptor subunit beta","termid":"PBO:0051530"}


id: GO:0060219
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.","definition_xrefs":["GOC:dph","GOC:tb","GOC:ascb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye photoreceptor cell differentiation","termid":"GO:0001754"},{"relation_name":"part_of","term_name":"neural retina development","termid":"GO:0003407"},{"relation_name":"part_of","term_name":"retina morphogenesis in camera-type eye","termid":"GO:0060042"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"camera-type eye photoreceptor cell differentiation","termid":"GO:0060219"}


id: FYPO:0007150
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the occurrence of microtubule bundle formation, which normally results in a parallel arrangement of microtubules, is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal microtubule bundle formation","termid":"FYPO:0002761"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000054","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased microtubule bundle formation","synonyms":[{"name":"decreased microtubule array formation","type":"related"},{"name":"decreased microtubule bundling","type":"exact"},{"name":"reduced microtubule bundle formation","type":"exact"}],"termid":"FYPO:0007150"}


id: PBO:0070727
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L9 pseudogene 32","termid":"PBO:0070727"}


id: GO:0034738
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sterol O-acyltransferase activity","termid":"GO:0004772"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016740","GO:0016746"],"is_obsolete":false,"name":"lanosterol O-acyltransferase activity","termid":"GO:0034738"}


id: PBO:0053377
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 303","termid":"PBO:0053377"}


id: PBO:0085607
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in control of glucose-regulated gene expression; interacts with kinase Snf1p, glucose sensors Snf3p and Rgt2p, TATA-binding Spt15p; regulator of transcription factor Rgt1p; interactions with Pma1p appear to propagate [GAR+]; STD1 has a paralog, MTH1, that arose from the whole genome duplication","termid":"PBO:0085607"}


id: MONDO:1012171
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"muscle contracture and chondrodysplasia, non-human animal","termid":"MONDO:1011947"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"muscle contracture and chondrodysplasia, cattle","secondary_identifiers":["OMIA:000675-9913"],"termid":"MONDO:1012171","xrefs":{"Monarch":{"xref_id":"1012171"}}}


id: MONDO:0002942
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"skin basal cell carcinoma","termid":"MONDO:0005341"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005093"],"is_obsolete":false,"name":"sebaceous basal cell carcinoma","secondary_identifiers":["UMLS:C0334683","MEDGEN:83180","DOID:4286","NCIT:C4346"],"synonyms":[{"name":"skin basosebaceous basal cell carcinoma","type":"exact"}],"termid":"MONDO:0002942","xrefs":{"Monarch":{"xref_id":"0002942"}}}


id: PBO:0091718
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar membrane palmitoyltransferase Pfa5","termid":"PBO:0091718"}


id: GO:0023048
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which a lipid signal causes activation of a receptor.","definition_xrefs":["GOC:mtg_signal"],"gene_count":0,"genotype_count":0,"name":"obsolete signal initiation by lipid mediator (obsolete GO:0023048)","synonyms":[{"name":"signal initiation by lipid mediator","type":"exact"}],"termid":"GO:0023048"}


id: FYPO:0001553
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is abnormal. RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.","definition_xrefs":["GO:0006396","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleic acid metabolism phenotype during vegetative growth","termid":"FYPO:0001347"},{"relation_name":"is_a","term_name":"abnormal metabolic process during vegetative growth","termid":"FYPO:0001363"},{"relation_name":"is_a","term_name":"abnormal RNA metabolic process","termid":"FYPO:0004851"},{"relation_name":"is_a","term_name":"abnormal gene expression","termid":"FYPO:0006551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000294"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0006551","FYPO:0005447","FYPO:0000294"],"is_obsolete":false,"name":"abnormal RNA processing","synonyms":[{"name":"abnormal RNA processing during mitotic cell cycle","type":"related"},{"name":"abnormal RNA processing during vegetative growth","type":"exact"}],"termid":"FYPO:0001553"}


id: MONDO:0003896
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A capillary hemangioma arising from the breast.","definition_xrefs":["NCIT:C5210"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"breast angiomatosis","termid":"MONDO:0002064"},{"relation_name":"is_a","term_name":"capillary hemangioma","termid":"MONDO:0002407"},{"relation_name":"is_a","term_name":"breast hemangioma","termid":"MONDO:0003126"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"breast capillary hemangioma","secondary_identifiers":["MEDGEN:231963","UMLS:C1332619","DOID:6491"],"synonyms":[{"name":"breast capillary angioma","type":"exact"},{"name":"breast capillary hemangioma","type":"exact"},{"name":"capillary angioma of breast","type":"exact"},{"name":"capillary angioma of the breast","type":"exact"},{"name":"capillary hemangioma of breast","type":"exact"},{"name":"capillary hemangioma of the breast","type":"exact"}],"termid":"MONDO:0003896","xrefs":{"Monarch":{"xref_id":"0003896"}}}


id: PBO:0091079
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-binding forkhead transcription factor, meiotic Mei4","termid":"PBO:0091079"}


id: PBO:0069931
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1224, pseudogene","termid":"PBO:0069931"}


id: MONDO:0014333
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"bilateral perisylvian polymicrogyria","termid":"MONDO:0020340"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"polymicrogyria, bilateral perisylvian, autosomal recessive","secondary_identifiers":["UMLS:C3810405","OMIM:615752","GARD:16009","MEDGEN:816735"],"synonyms":[{"name":"BPPR","type":"related"},{"name":"Pmgr","type":"related"},{"name":"polymicrogyria, bilateral perisylvian","type":"exact"},{"name":"polymicrogyria, bilateral perisylvian, autosomal recessive","type":"exact"}],"termid":"MONDO:0014333","xrefs":{"Monarch":{"xref_id":"0014333"}}}


id: GO:0002931
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to stress","termid":"GO:0006950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to ischemia","termid":"GO:0002931"}


id: PBO:0065488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proteasome activator subunit 3","termid":"PBO:0065488"}


id: PBO:0038754
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ACTR3 antisense RNA 1","termid":"PBO:0038754"}


id: GO:0044541
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism.","definition_xrefs":["GOC:fj","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete zymogen activation in another organism (obsolete GO:0044541)","synonyms":[{"name":"zymogen activation in other organism","type":"exact"}],"termid":"GO:0044541"}


id: GO:0008110
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.","definition_xrefs":["EC:2.6.1.38","RHEA:16565"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transaminase activity","termid":"GO:0008483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016769"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0003674","GO:0016769"],"is_obsolete":false,"name":"L-histidine:2-oxoglutarate aminotransferase activity","secondary_identifiers":["MetaCyc:HISTTRANSAM-RXN","KEGG_REACTION:R01161"],"synonyms":[{"name":"histidine aminotransferase activity","type":"broad"},{"name":"histidine transaminase activity","type":"broad"},{"name":"histidine-2-oxoglutarate aminotransferase activity","type":"related"}],"termid":"GO:0008110"}


id: GO:0060861
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.","definition_xrefs":["GOC:tb","GOC:dph","GOC:sdb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of floral organ abscission","termid":"GO:0060860"},{"relation_name":"is_a","term_name":"positive regulation of reproductive process","termid":"GO:2000243"},{"relation_name":"positively_regulates","term_name":"floral organ abscission","termid":"GO:0010227"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of floral organ abscission","termid":"GO:0060861"}


id: PBO:0044650
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DCTN1 antisense RNA 1","termid":"PBO:0044650"}


id: PBO:0028344
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_microtubule_cytoskeleton_during_vegetative_growth","termid":"PBO:0028344"}


id: PBO:0064840
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 1 regulatory subunit 12B","termid":"PBO:0064840"}


id: PBO:0089004
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase His6","termid":"PBO:0089004"}


id: MONDO:0001495
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hemorrhage into a canal or cavity of the body, such as the space covered by the serous membrane (tunica vaginalis) around the testis leading to testicular hematocele or scrotal hematocele.","definition_xrefs":["MESH:D006398"],"direct_ancestors":[{"relation_name":"is_a","term_name":"male reproductive system disorder","termid":"MONDO:0003150"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hematocele of tunica vaginalis testis","secondary_identifiers":["DOID:12332","MEDGEN:42386","SCTID:66259004","UMLS:C0018931"],"synonyms":[{"name":"hematocele","type":"exact"},{"name":"male hematocele","type":"exact"}],"termid":"MONDO:0001495","xrefs":{"Monarch":{"xref_id":"0001495"}}}


id: MONDO:0001798
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"arthropathy","termid":"MONDO:0006816"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypermobility syndrome","secondary_identifiers":["ICD9:728.5","MEDGEN:508885","DOID:13781","ICD10CM:M35.7","SCTID:85551004","UMLS:C0152093"],"synonyms":[{"name":"benign joint hypermobility","type":"exact"}],"termid":"MONDO:0001798","xrefs":{"Monarch":{"xref_id":"0001798"}}}


id: GO:1902667
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of axon guidance.","definition_xrefs":["GOC:hjd","PMID:23006775","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of neuron projection development","termid":"GO:0010975"},{"relation_name":"is_a","term_name":"regulation of chemotaxis","termid":"GO:0050920"},{"relation_name":"regulates","term_name":"axon guidance","termid":"GO:0007411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of axon guidance","synonyms":[{"name":"regulation of axon chemotaxis","type":"related"},{"name":"regulation of axon growth cone guidance","type":"narrow"},{"name":"regulation of axon pathfinding","type":"exact"}],"termid":"GO:1902667"}


id: GO:0015990
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The transport of protons against an electrochemical gradient, using energy from electron transport.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"energy coupled proton transmembrane transport, against electrochemical gradient","termid":"GO:0015988"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"electron transport coupled proton transport","termid":"GO:0015990"}


id: GO:0048754
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.","definition_xrefs":["GOC:dgh","GOC:dph","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tube morphogenesis","termid":"GO:0035239"},{"relation_name":"is_a","term_name":"morphogenesis of a branching epithelium","termid":"GO:0061138"},{"relation_name":"part_of","term_name":"epithelial tube morphogenesis","termid":"GO:0060562"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"branching morphogenesis of an epithelial tube","synonyms":[{"name":"tubulogenesis","type":"related"}],"termid":"GO:0048754"}


id: MONDO:0013736
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete myopathy, centronuclear, 3 (obsolete MONDO:0013736)","termid":"MONDO:0013736","xrefs":{"Monarch":{"xref_id":"0013736"}}}


id: GO:0005194
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Mediates the adhesion of the cell to other cells or to the extracellular matrix.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete cell adhesion molecule activity (obsolete GO:0005194)","synonyms":[{"name":"cell adhesion molecule activity","type":"exact"}],"termid":"GO:0005194"}


id: PBO:0075940
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SH3 and cysteine rich domain 3","termid":"PBO:0075940"}


id: MONDO:0014706
data:
  {"annotated_genes":["SJAG_03457","SJAG_00660"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86349,86350],"is_not":false,"summary":null,"term":"MONDO:0014706"}]},"cv_name":"mondo","definition":"An autosomal dominant cutis laxa characterized by thin skin with visible veins and wrinkles, cataract or corneal clouding, clenched fingers, pre- and postnatal growth retardation, moderate intellectual disability, and a combination of muscle hypotonia with brisk muscle reflexes that has material basis in heterozygous mutation in the ALDH18A1 gene on chromosome 10q24.","definition_xrefs":["DOID:0070131"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"autosomal dominant cutis laxa","termid":"MONDO:0019571"},{"relation_name":"is_a","term_name":"P5CS deficiency","termid":"MONDO:0100126"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00660":null,"SJAG_03457":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0004736","MONDO:0005328","MONDO:0005066"],"is_obsolete":false,"name":"cutis laxa, autosomal dominant 3","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:899774","UMLS:C4225268","GARD:16143","OMIM:616603"],"synonyms":[{"name":"ADCL3","type":"exact"},{"name":"autosomal dominant cutis laxa 3","type":"related"},{"name":"cutis laxa, autosomal dominant 3","type":"exact"},{"name":"cutis laxa, autosomal dominant type 3","type":"exact"}],"termid":"MONDO:0014706","terms_by_termid":{"MONDO:0014706":null},"xrefs":{"Monarch":{"xref_id":"0014706"}}}


id: PBO:0047574
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibroblast growth factor binding protein 2","termid":"PBO:0047574"}


id: GO:0060464
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure formation involved in morphogenesis","termid":"GO:0048646"},{"relation_name":"part_of","term_name":"lung lobe morphogenesis","termid":"GO:0060463"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lung lobe formation","termid":"GO:0060464"}


id: GO:0140329
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.","definition_xrefs":["PMID:15661733"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid translocation","termid":"GO:0045332"},{"relation_name":"is_a","term_name":"lysophospholipid transport","termid":"GO:0051977"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0061024","GO:0008150"],"is_obsolete":false,"name":"lysophospholipid translocation","termid":"GO:0140329"}


id: PBO:0058913
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 12131","termid":"PBO:0058913"}


id: PBO:0001614
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipase (predicted)","termid":"PBO:0001614"}


id: FYPO:0002753
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing sulfate ions as the sole sulfur source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished vegetative cell population growth","termid":"FYPO:0001575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0002057","FYPO:0002058","FYPO:0000139","FYPO:0000003","FYPO:0001985","FYPO:0002060","FYPO:0005447"],"is_obsolete":false,"name":"abolished cell population growth on sulfate sulfur source","synonyms":[{"name":"abolished cell population growth on sulphate sulphur source","type":"exact"},{"name":"abolished growth on sulfate sulfur source","type":"broad"},{"name":"abolished sulfate utilization","type":"related"},{"name":"abolished vegetative cell population growth on sulfate ion sulfur source","type":"exact"},{"name":"cell population growth on sulfate sulfur source abolished","type":"exact"},{"name":"inability to utilize sulphate as sole sulphur source","type":"related"}],"termid":"FYPO:0002753"}


id: PBO:0085531
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S29 and bacterial S14; RPS29B has a paralog, RPS29A, that arose from the whole genome duplication","termid":"PBO:0085531"}


id: MONDO:0020549
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A complete hydatidiform mole or very rarely a partial mole that invades the myometrium.","definition_xrefs":["NCIT:C6985"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydatidiform mole","termid":"MONDO:0006248"},{"relation_name":"is_a","term_name":"gestational trophoblastic neoplasm","termid":"MONDO:0018944"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"invasive hydatidiform mole","secondary_identifiers":["MESH:D002820","MEDGEN:3055","GARD:19711","Orphanet:99925","ONCOTREE:IHM","ICDO:9100/1","SCTID:416669000","UMLS:C0008493"],"synonyms":[{"name":"IHM","type":"related"},{"name":"chorioadenoma","type":"exact"},{"name":"chorioadenoma Destruens","type":"exact"},{"name":"chorioadenoma destruens","type":"exact"},{"name":"invasive Mole","type":"exact"},{"name":"invasive gestational trophoblastic neoplasm","type":"exact"},{"name":"invasive hydatidiform Mole","type":"exact"},{"name":"invasive hydatidiform mole","type":"exact"}],"termid":"MONDO:0020549","xrefs":{"Monarch":{"xref_id":"0020549"}}}


id: FYPO:0005940
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which the replicative lifespan of a cell population, i.e. the number of divisions cells in the population undergo before death, is higher than normal.","definition_xrefs":["PomBase:mah","PMID:28139976"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population phenotype","termid":"FYPO:0000003"},{"relation_name":"is_a","term_name":"abnormal phenotype","termid":"FYPO:0001985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"increased replicative lifespan","synonyms":[{"name":"increased cell population replicative lifespan","type":"exact"},{"name":"increased population replicative lifespan","type":"exact"}],"termid":"FYPO:0005940"}


id: PBO:0050121
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 31","termid":"PBO:0050121"}


id: PATO:0002541
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Pertaining to the ability or tendency of an organism or cell to maintain internal equilibrium by adjusting its physiological processes.","definition_xrefs":["GO:0042592"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organismal quality","termid":"PATO:0001995"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homeostatic","termid":"PATO:0002541"}


id: MONDO:0060486
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"arthrogryposis multiplex congenita","termid":"MONDO:0015168"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"arthrogryposis multiplex congenita 1, neurogenic, with myelin defect","secondary_identifiers":["GARD:18566","OMIM:617468","MEDGEN:1373185","UMLS:C4479539","DOID:0080978"],"synonyms":[{"name":"AMCNMY","type":"related"},{"name":"arthrogryposis multiplex congenita, neurogenic, with myelin defect","type":"exact"}],"termid":"MONDO:0060486","xrefs":{"Monarch":{"xref_id":"0060486"}}}


id: PBO:0074718
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 78","termid":"PBO:0074718"}


id: GO:0019824
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.","definition_xrefs":["PMID:10629216"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peroxisome","termid":"GO:0005777"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0005777"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0005777"],"is_obsolete":false,"name":"P6 peroxisome","synonyms":[{"name":"peroxisome vesicle","type":"broad"}],"termid":"GO:0019824"}


id: PBO:0004629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N2,N2-dimethylguanosine tRNA methyltransferase","termid":"PBO:0004629"}


id: MONDO:0003397
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Abnormal enlargement or overgrowth of the gingivae brought about by enlargement of existing cells.","definition_xrefs":["MESH:D005886"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gingival overgrowth","termid":"MONDO:0002507"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gingival hypertrophy","secondary_identifiers":["MEDGEN:6603","UMLS:C0017567","DOID:5338"],"synonyms":[{"name":"hypertrophy of gingivae","type":"exact"}],"termid":"MONDO:0003397","xrefs":{"Monarch":{"xref_id":"0003397"}}}


id: PBO:0056848
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mahogunin ring finger 1","termid":"PBO:0056848"}


id: FYPO:0001086
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a glucosyltransferase activity is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal catalytic activity","termid":"FYPO:0000660"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000652","FYPO:0000257"],"is_obsolete":false,"name":"normal glucosyltransferase activity","termid":"FYPO:0001086"}


id: GO:1905580
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway.","definition_xrefs":["PMID:27353365","GOC:TermGenie","GO_REF:0000058","GOC:als"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of ERBB signaling pathway","termid":"GO:1901186"},{"relation_name":"is_a","term_name":"regulation of ERBB3 signaling pathway","termid":"GO:1905578"},{"relation_name":"positively_regulates","term_name":"ERBB3 signaling pathway","termid":"GO:0038129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of ERBB3 signaling pathway","synonyms":[{"name":"activation of ERBB3 signaling pathway","type":"narrow"},{"name":"activation of ERBB3 signalling pathway","type":"narrow"},{"name":"activation of HER3 signaling pathway","type":"narrow"},{"name":"activation of receptor tyrosine-protein kinase erbB-3 signaling pathway","type":"narrow"},{"name":"positive regulation of ERBB3 signalling pathway","type":"exact"},{"name":"positive regulation of HER3 signaling pathway","type":"exact"},{"name":"positive regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway","type":"exact"},{"name":"up regulation of ERBB3 signaling pathway","type":"exact"},{"name":"up regulation of ERBB3 signalling pathway","type":"exact"},{"name":"up regulation of HER3 signaling pathway","type":"exact"},{"name":"up regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway","type":"exact"},{"name":"up-regulation of ERBB3 signaling pathway","type":"exact"},{"name":"up-regulation of ERBB3 signalling pathway","type":"exact"},{"name":"up-regulation of HER3 signaling pathway","type":"exact"},{"name":"up-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway","type":"exact"},{"name":"upregulation of ERBB3 signaling pathway","type":"exact"},{"name":"upregulation of ERBB3 signalling pathway","type":"exact"},{"name":"upregulation of HER3 signaling pathway","type":"exact"},{"name":"upregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway","type":"exact"}],"termid":"GO:1905580"}


id: PBO:0111831
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromodomain protein","termid":"PBO:0111831"}


id: MONDO:0009441
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive congenital ichthyosis in which the cause of the disease is a mutation in the TGM1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive congenital ichthyosis","termid":"MONDO:0017265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"autosomal recessive congenital ichthyosis 1","secondary_identifiers":["MESH:D017490","DOID:0060656","MEDGEN:1635401","OMIM:242300","UMLS:C4551630","GARD:3170"],"synonyms":[{"name":"ARCI1","type":"exact"},{"name":"LI1","type":"related"},{"name":"autosomal recessive congenital ichthyosis 1","type":"exact"},{"name":"autosomal recessive congenital ichthyosis type 1","type":"exact"},{"name":"bathing suit ichthyosis","type":"narrow"},{"name":"collodion baby, self-healing","type":"related"},{"name":"collodion fetus","type":"related"},{"name":"collodion foetus","type":"related"},{"name":"desquamation of newborn","type":"related"},{"name":"ichthyosis congenita","type":"related"},{"name":"ichthyosis congenita 2","type":"related"},{"name":"ichthyosis lamellar 1","type":"related"},{"name":"ichthyosis, congenital, autosomal recessive 1","type":"related"},{"name":"ichthyosis, congenital, autosomal recessive 1, with bathing suit distribution","type":"related"},{"name":"ichthyosis, congenital, autosomal recessive type 1","type":"exact"},{"name":"ichthyosis, lamellar, 1","type":"related"},{"name":"ichthyosis, lamellar, 1, formerly","type":"related"},{"name":"lamellar exfoliation of newborn","type":"related"},{"name":"lamellar ichthyosis, type 1","type":"related"}],"termid":"MONDO:0009441","xrefs":{"Monarch":{"xref_id":"0009441"}}}


id: GO:0070277
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete iodide oxidation (obsolete GO:0070277)","termid":"GO:0070277"}


id: PBO:0074966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 114-8","termid":"PBO:0074966"}


id: GO:0150058
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signaling pathways.","definition_xrefs":["GOC:aruk","PMID:22500019","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amylin receptor complex","termid":"GO:1903440"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0032991","GO:0005886","GO:0005575"],"is_obsolete":false,"name":"amylin receptor complex 3","synonyms":[{"name":"AMY3 complex","type":"exact"}],"termid":"GO:0150058"}


id: GO:2000647
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell population proliferation","termid":"GO:0008285"},{"relation_name":"is_a","term_name":"regulation of stem cell proliferation","termid":"GO:0072091"},{"relation_name":"negatively_regulates","term_name":"stem cell proliferation","termid":"GO:0072089"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of stem cell proliferation","termid":"GO:2000647"}


id: PBO:0052033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"JRKL antisense RNA 1","termid":"PBO:0052033"}


id: PBO:0052759
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 18 pseudogene 51","termid":"PBO:0052759"}


id: GO:0042962
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).","definition_xrefs":["PMID:10735876"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proton transmembrane transporter activity","termid":"GO:0015078"},{"relation_name":"is_a","term_name":"antiporter activity","termid":"GO:0015297"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"acridine:proton antiporter activity","synonyms":[{"name":"acridine efflux pump activity","type":"related"},{"name":"acridine:hydrogen antiporter activity","type":"exact"}],"termid":"GO:0042962"}


id: PR:Q8TFH2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAPB17E12.12c gene.","definition_xrefs":["UniProtKB:Q8TFH2","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized mitochondrial carrier PB17E12.12c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB17E12.12c","synonyms":[{"name":"Spom972h-SPAPB17E12.12c","type":"exact"}],"termid":"PR:Q8TFH2"}


id: MONDO:0006714
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Abnormal balloon- or sac-like dilatation in the wall of coronary vessels. Most coronary aneurysms are due to coronary atherosclerosis, and the rest are due to inflammatory diseases, such as kawasaki disease.","definition_xrefs":["MESH:D003323"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"heart aneurysm","termid":"MONDO:0006779"},{"relation_name":"is_a","term_name":"coronary artery disorder","termid":"MONDO:0005010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"coronary aneurysm","secondary_identifiers":["SCTID:50570003","MedDRA:10002348","ICD9:414.11","UMLS:C0010051","EFO:1000881","HP:0030882","MEDGEN:3622","DOID:3362"],"synonyms":[{"name":"aneurysm of coronary vessels","type":"exact"},{"name":"aneurysmal lesion of coronary artery","type":"exact"},{"name":"arteriovenous aneurysm of coronary vessels","type":"exact"},{"name":"coronary artery aneurysm","type":"related"}],"termid":"MONDO:0006714","xrefs":{"Monarch":{"xref_id":"0006714"}}}


id: MONDO:0100308
data:
  {"annotated_genes":["SJAG_01854","SJAG_00421","SJAG_04233","SJAG_00380","SJAG_02457","SJAG_01168","SJAG_00686","SJAG_04622","SJAG_00721","SJAG_02377","SJAG_00773","SJAG_03720","SJAG_03692","SJAG_02084","SJAG_02119","SJAG_03393","SJAG_05332","SJAG_00797","SJAG_00863","SJAG_00933","SJAG_02196","SJAG_01286","SJAG_04110","SJAG_01356","SJAG_01945","SJAG_04418","SJAG_02680","SJAG_00087","SJAG_01317","SJAG_02242","SJAG_01438","SJAG_03862","SJAG_04641","SJAG_00526","SJAG_00059","SJAG_04533","SJAG_04822","SJAG_02885","SJAG_01179","SJAG_00645","SJAG_03923","SJAG_01417","SJAG_01400","SJAG_16456","SJAG_05212"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86241],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014744"},{"annotations":[85783],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014557"},{"annotations":[85758],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008840"},{"annotations":[87216],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008980"},{"annotations":[86259],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0016163"},{"annotations":[87147],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011397"},{"annotations":[86544],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012166"},{"annotations":[86660],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012784"},{"annotations":[87380],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013392"},{"annotations":[87060],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014503"},{"annotations":[85519],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008943"},{"annotations":[85632],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014601"},{"annotations":[86808],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044720"},{"annotations":[85374],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014104"},{"annotations":[86522],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013886"},{"annotations":[87136],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011402"},{"annotations":[85898],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0100340"},{"annotations":[87455],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0958231"},{"annotations":[86434],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0958009"},{"annotations":[87096],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012651"},{"annotations":[85844],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012664"},{"annotations":[87409],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013354"},{"annotations":[87019],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013776"},{"annotations":[86153],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014803"},{"annotations":[86348],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033482"},{"annotations":[86036],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011330"},{"annotations":[85600],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011439"},{"annotations":[86114],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011781"},{"annotations":[87616],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008458"},{"annotations":[85552,85553],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012246"},{"annotations":[85538],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012450"},{"annotations":[85998,85999],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007574"},{"annotations":[86193],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013594"},{"annotations":[86642,86643],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014417"},{"annotations":[87506],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014934"},{"annotations":[85777],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033115"},{"annotations":[85848],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032923"},{"annotations":[86916],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030312"},{"annotations":[86679,86678],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030318"},{"annotations":[86685],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030323"},{"annotations":[85956],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011801"},{"annotations":[86966,86967],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0018996"},{"annotations":[85971],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010547"},{"annotations":[86102],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010524"}]},"cv_name":"mondo","definition":"A central nervous system disease that consists of gait impairment, unclear (“scanning”) speech, visual blurring due to nystagmus, hand incoordination, and tremor with movement.","definition_xrefs":["ISBN-13:978-1-259-64403-0"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"central nervous system disorder","termid":"MONDO:0002602"},{"relation_name":"is_a","term_name":"nervous system disorder","termid":"MONDO:0005071"}],"gene_count":45,"genes_by_uniquename":{"SJAG_00059":null,"SJAG_00087":null,"SJAG_00380":null,"SJAG_00421":null,"SJAG_00526":null,"SJAG_00645":null,"SJAG_00686":null,"SJAG_00721":null,"SJAG_00773":null,"SJAG_00797":null,"SJAG_00863":null,"SJAG_00933":null,"SJAG_01168":null,"SJAG_01179":null,"SJAG_01286":null,"SJAG_01317":null,"SJAG_01356":null,"SJAG_01400":null,"SJAG_01417":null,"SJAG_01438":null,"SJAG_01854":null,"SJAG_01945":null,"SJAG_02084":null,"SJAG_02119":null,"SJAG_02196":null,"SJAG_02242":null,"SJAG_02377":null,"SJAG_02457":null,"SJAG_02680":null,"SJAG_02885":null,"SJAG_03393":null,"SJAG_03692":null,"SJAG_03720":null,"SJAG_03862":null,"SJAG_03923":null,"SJAG_04110":null,"SJAG_04233":null,"SJAG_04418":null,"SJAG_04533":null,"SJAG_04622":null,"SJAG_04641":null,"SJAG_04822":null,"SJAG_05212":null,"SJAG_05332":null,"SJAG_16456":null},"genotype_count":0,"is_obsolete":false,"name":"atactic disorder","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"ataxia","type":"related"},{"name":"ataxic disorder","type":"exact"}],"termid":"MONDO:0100308","terms_by_termid":{"MONDO:0007574":null,"MONDO:0008458":null,"MONDO:0008840":null,"MONDO:0008943":null,"MONDO:0008980":null,"MONDO:0010524":null,"MONDO:0010547":null,"MONDO:0011330":null,"MONDO:0011397":null,"MONDO:0011402":null,"MONDO:0011439":null,"MONDO:0011781":null,"MONDO:0011801":null,"MONDO:0012166":null,"MONDO:0012246":null,"MONDO:0012450":null,"MONDO:0012651":null,"MONDO:0012664":null,"MONDO:0012784":null,"MONDO:0013354":null,"MONDO:0013392":null,"MONDO:0013594":null,"MONDO:0013776":null,"MONDO:0013886":null,"MONDO:0014104":null,"MONDO:0014417":null,"MONDO:0014503":null,"MONDO:0014557":null,"MONDO:0014601":null,"MONDO:0014744":null,"MONDO:0014803":null,"MONDO:0014934":null,"MONDO:0016163":null,"MONDO:0018996":null,"MONDO:0030312":null,"MONDO:0030318":null,"MONDO:0030323":null,"MONDO:0032923":null,"MONDO:0033115":null,"MONDO:0033482":null,"MONDO:0044720":null,"MONDO:0100340":null,"MONDO:0958009":null,"MONDO:0958231":null},"xrefs":{"Monarch":{"xref_id":"0100308"}}}


id: MONDO:0017423
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete non-syndromic terminal limb defects (obsolete MONDO:0017421)","termid":"MONDO:0017421"}],"gene_count":0,"genotype_count":0,"name":"obsolete split hand or/and split foot malformation (obsolete MONDO:0017423)","secondary_identifiers":["Orphanet:294935"],"termid":"MONDO:0017423","xrefs":{"Monarch":{"xref_id":"0017423"}}}


id: PBO:0018292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit Med19","termid":"PBO:0018292"}


id: GO:0034327
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, transferring groups other than amino-acyl groups","termid":"GO:0016747"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0016746","GO:0016740","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"hexanoyltransferase activity","termid":"GO:0034327"}


id: MONDO:0032910
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial complex I deficiency, nuclear type","termid":"MONDO:0100223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial complex 1 deficiency, nuclear type 34","secondary_identifiers":["UMLS:C5394053","DOID:0112091","OMIM:618776","MEDGEN:1720533","GARD:16378"],"synonyms":[{"name":"MC1DN34","type":"related"},{"name":"MITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 34","type":"related"}],"termid":"MONDO:0032910","xrefs":{"Monarch":{"xref_id":"0032910"}}}


id: GO:0006740
data:
  {"annotated_genes":["SJAG_00501","SJAG_03934","SJAG_03852","SJAG_00070","SJAG_00633","SJAG_00685","SJAG_05314","SJAG_01824","SJAG_02148","SJAG_04263","SJAG_03174","SJAG_02297","SJAG_02696"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[68385],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006098"},{"annotations":[73453,74878,74087,108739,104669],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0009052"},{"annotations":[73419,97222,97311,80742,98509],"is_not":false,"rel_names":["is_a","part_of"],"summary":null,"term":"GO:0009051"},{"annotations":[90033],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1905857"},{"annotations":[76376],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0043456"}]},"cv_name":"biological_process","definition":"A metabolic process that generates a pool of NADPH by the reduction of NADP+.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"generation of precursor metabolites and energy","termid":"GO:0006091"},{"relation_name":"is_a","term_name":"NADP metabolic process","termid":"GO:0006739"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00070":null,"SJAG_00501":null,"SJAG_00633":null,"SJAG_00685":null,"SJAG_01824":null,"SJAG_02148":null,"SJAG_02297":null,"SJAG_02696":null,"SJAG_03174":null,"SJAG_03852":null,"SJAG_03934":null,"SJAG_04263":null,"SJAG_05314":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0006091"}],"interesting_parent_ids":["GO:0006091","GO:0055086","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"NADPH regeneration","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-389542"],"synonyms":[{"name":"NADP (reduced) regeneration","type":"exact"},{"name":"reduced NADP regeneration","type":"exact"},{"name":"reduced nicotinamide adenine dinucleotide phosphate regeneration","type":"exact"}],"termid":"GO:0006740","terms_by_termid":{"GO:0006098":null,"GO:0009051":null,"GO:0009052":null,"GO:0043456":null,"GO:1905857":null}}


id: GO:0007318
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization","termid":"GO:0008104"},{"relation_name":"part_of","term_name":"pole plasm assembly","termid":"GO:0007315"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0044085"],"is_obsolete":false,"name":"pole plasm protein localization","secondary_identifiers":["GO:0048115"],"synonyms":[{"name":"establishment and maintenance of pole plasm protein localization","type":"exact"},{"name":"oocyte pole plasm protein localization","type":"exact"},{"name":"pole plasm protein localisation","type":"exact"}],"termid":"GO:0007318"}


id: GO:0018163
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.","definition_xrefs":["RESID:AA0254"],"gene_count":0,"genotype_count":0,"name":"obsolete protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine (obsolete GO:0018163)","synonyms":[{"name":"DNA-protein covalent cross-linking via the 5' end to peptidyl-tyrosine","type":"exact"}],"termid":"GO:0018163"}


id: PBO:0086711
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene","termid":"PBO:0086711"}


id: MONDO:0020623
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete blood group--ul system (obsolete MONDO:0020623)","secondary_identifiers":["OMIM:112000"],"synonyms":[{"name":"BLOOD GROUP--Ul SYSTEM","type":"related"},{"name":"UL","type":"related"}],"termid":"MONDO:0020623","xrefs":{"Monarch":{"xref_id":"0020623"}}}


id: PBO:0046729
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"envoplakin like","termid":"PBO:0046729"}


id: MONDO:0100525
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A newly discovered disorder caused by a change (variant or mutation) in the TCF7L2 gene. This mutation may be responsible for developmental delays in childhood, intellectual disability, autism, myopia, ADHD, abnormal physical features and other problems. There is a wide spectrum of severity for individuals affected with TRND. Many of the symptoms of TRND overlap with other neurodevelopmental disorders. TRND must be diagnosed with a genetic test and cannot be diagnosed by symptoms alone.","definition_xrefs":["PMID:34003604"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurodevelopmental disorder","termid":"MONDO:0700092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"TCF7L2-related neurodevelopmental disorder","termid":"MONDO:0100525","xrefs":{"Monarch":{"xref_id":"0100525"}}}


id: MONDO:0014315
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Mitchell-Riley syndrome (obsolete MONDO:0014315)","termid":"MONDO:0014315","xrefs":{"Monarch":{"xref_id":"0014315"}}}


id: MONDO:1011308
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital nervous system disorder that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nervous system disorder, non-human animal","termid":"MONDO:1011336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital nervous system disorder, non-human animal","termid":"MONDO:1011308","xrefs":{"Monarch":{"xref_id":"1011308"}}}


id: PBO:0087012
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribonuclease H2 subunit; required for RNase H2 activity; role in ribonucleotide excision repair; related to human AGS3 that causes Aicardi-Goutieres syndrome","termid":"PBO:0087012"}


id: GO:1901897
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.","definition_xrefs":["GOC:BHF","PMID:19708671","GOC:TermGenie","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of relaxation of muscle","termid":"GO:1901077"},{"relation_name":"regulates","term_name":"relaxation of cardiac muscle","termid":"GO:0055119"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of relaxation of cardiac muscle","termid":"GO:1901897"}


id: GO:0060169
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of G protein-coupled receptor signaling pathway","termid":"GO:0045744"},{"relation_name":"is_a","term_name":"regulation of adenosine receptor signaling pathway","termid":"GO:0060167"},{"relation_name":"negatively_regulates","term_name":"G protein-coupled adenosine receptor signaling pathway","termid":"GO:0001973"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of adenosine receptor signaling pathway","synonyms":[{"name":"negative regulation of adenosine receptor signalling pathway","type":"exact"}],"termid":"GO:0060169"}


id: PBO:0058543
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6089","termid":"PBO:0058543"}


id: PBO:0052454
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KLF transcription factor 5","termid":"PBO:0052454"}


id: GO:0033344
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.","definition_xrefs":["GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cholesterol transport","termid":"GO:0030301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"cholesterol efflux","synonyms":[{"name":"cholesterol export","type":"exact"}],"termid":"GO:0033344"}


id: MONDO:0003665
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cervical adenocarcinoma with the histologic characteristics of the endometrioid adenocarcinoma of the endometrium.","definition_xrefs":["NCIT:C6343"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endometrioid adenocarcinoma","termid":"MONDO:0005026"},{"relation_name":"is_a","term_name":"cervical adenocarcinoma","termid":"MONDO:0005153"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"cervical endometrioid adenocarcinoma","secondary_identifiers":["DOID:5830","ONCOTREE:CEEN","EFO:1000164","MEDGEN:272450","UMLS:C1332913"],"synonyms":[{"name":"cervical endometrioid adenocarcinoma","type":"exact"},{"name":"cervical endometrioid carcinoma","type":"exact"},{"name":"cervix endometrioid adenocarcinoma","type":"exact"},{"name":"cervix endometrioid carcinoma","type":"exact"},{"name":"cervix uteri endometrioid adenocarcinoma","type":"exact"},{"name":"cervix uteri endometrioid carcinoma","type":"exact"},{"name":"endometrioid adenocarcinoma of cervix","type":"exact"},{"name":"endometrioid adenocarcinoma of cervix uteri","type":"exact"},{"name":"endometrioid adenocarcinoma of the cervix","type":"exact"},{"name":"endometrioid adenocarcinoma of the cervix uteri","type":"exact"},{"name":"endometrioid adenocarcinoma of the uterine cervix","type":"exact"},{"name":"endometrioid adenocarcinoma of uterine cervix","type":"exact"},{"name":"endometrioid carcinoma of cervix","type":"exact"},{"name":"endometrioid carcinoma of cervix uteri","type":"exact"},{"name":"endometrioid carcinoma of the cervix","type":"exact"},{"name":"endometrioid carcinoma of the cervix uteri","type":"exact"},{"name":"endometrioid carcinoma of the uterine cervix","type":"exact"},{"name":"endometrioid carcinoma of uterine cervix","type":"exact"},{"name":"uterine cervix endometrioid adenocarcinoma","type":"exact"},{"name":"uterine cervix endometrioid carcinoma","type":"exact"}],"termid":"MONDO:0003665","xrefs":{"Monarch":{"xref_id":"0003665"}}}


id: FYPO:0000653
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"binding phenotype","termid":"FYPO:0001092"}],"gene_count":0,"genotype_count":0,"in_subsets":["fypo_slim"],"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0000652"],"is_obsolete":false,"name":"DNA binding phenotype","synonyms":[{"name":"fission yeast DNA binding phenotype","type":"exact"}],"termid":"FYPO:0000653"}


id: FYPO:0001625
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal level of substance in vacuole","termid":"FYPO:0001603"},{"relation_name":"is_a","term_name":"normal cellular glutamine level","termid":"FYPO:0001636"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal vacuolar glutamine level","synonyms":[{"name":"normal level of glutamine in vacuole","type":"exact"},{"name":"normal vacuolar L-glutamine level","type":"exact"},{"name":"normal vacuolar glutamine level during mitotic cell cycle","type":"related"},{"name":"normal vacuolar glutamine level during vegetative growth","type":"exact"}],"termid":"FYPO:0001625"}


id: PBO:0114412
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific microprotein Tam11","termid":"PBO:0114412"}


id: PBO:0058956
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP kinase interacting serine/threonine kinase 2 pseudogene 1","termid":"PBO:0058956"}


id: PBO:0117105
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RFT1 glycolipid translocator homolog","termid":"PBO:0117105"}


id: PBO:0071293
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L26 pseudogene 16","termid":"PBO:0071293"}


id: PBO:0041206
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bystin like","termid":"PBO:0041206"}


id: MONDO:0006858
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disease involving the mouth.","direct_ancestors":[{"relation_name":"is_a","term_name":"human disease","termid":"MONDO:0700096"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mouth disorder","secondary_identifiers":["SCTID:118938008","NCIT:C3240","EFO:1001047","ICD9:528.9","MESH:D009059","MEDGEN:6448","DOID:403","UMLS:C0026636"],"synonyms":[{"name":"disease of mouth","type":"exact"},{"name":"disease or disorder of mouth","type":"exact"},{"name":"disorder of mouth","type":"exact"},{"name":"mouth disease","type":"exact"},{"name":"mouth disease or disorder","type":"exact"},{"name":"oral disease","type":"exact"},{"name":"oral disorder","type":"exact"}],"termid":"MONDO:0006858","xrefs":{"Monarch":{"xref_id":"0006858"}}}


id: MONDO:0012214
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial glucocorticoid deficiency","termid":"MONDO:0008733"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucocorticoid deficiency 3","secondary_identifiers":["MEDGEN:332252","GARD:15450","MESH:C563776","OMIM:609197","UMLS:C1836621"],"synonyms":[{"name":"GCCD3","type":"exact"},{"name":"familial glucocorticoid deficiency 3","type":"related"},{"name":"glucocorticoid deficiency 2","type":"related"},{"name":"glucocorticoid deficiency 2, formerly","type":"related"},{"name":"glucocorticoid deficiency 3","type":"exact"}],"termid":"MONDO:0012214","xrefs":{"Monarch":{"xref_id":"0012214"}}}


id: GO:0030984
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a kininogen, a kinin precursor.","definition_xrefs":["GOC:mah","PMID:9520414"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0003674","GO:0005515"],"is_obsolete":false,"name":"kininogen binding","termid":"GO:0030984"}


id: PBO:0027010
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_elongated_mononucleate_aseptate_vegetative_cell_with_cell_cycle_arrest_in_mitotic_G2_phase","termid":"PBO:0027010"}


id: MONDO:0012544
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Brachydactyly-syndactyly, Zhao type is a recently described syndrome associating a brachydactyly type A4 (short middle phalanges of the 2nd and 5th fingers and absence of middle phalanges of the 2nd to 5th toes) and a syndactyly of the 2nd and 3rd toes. Metacarpals and metatarsals anomalies are common.","definition_xrefs":["Orphanet:93409"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal genetic disease","termid":"MONDO:0000429"},{"relation_name":"is_a","term_name":"skeletal system disorder","termid":"MONDO:0005172"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brachydactyly-syndactyly syndrome","secondary_identifiers":["MEDGEN:377836","MESH:C565193","GARD:16821","OMIM:610713","UMLS:C1853137","DOID:0050689"],"synonyms":[{"name":"BDSD","type":"related"},{"name":"Bdsd","type":"related"},{"name":"brachydactyly-syndactyly syndrome","type":"exact"},{"name":"brachydactyly-syndactyly, Zhao type","type":"related"},{"name":"brachydactyly-syndactyly-oligodactyly syndrome","type":"related"}],"termid":"MONDO:0012544","xrefs":{"Monarch":{"xref_id":"0012544"}}}


id: GO:2000548
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of plasma membrane bounded cell projection assembly","termid":"GO:0120033"},{"relation_name":"is_a","term_name":"regulation of dendritic cell dendrite assembly","termid":"GO:2000547"},{"relation_name":"negatively_regulates","term_name":"dendritic cell dendrite assembly","termid":"GO:0097026"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"negative regulation of dendritic cell dendrite assembly","synonyms":[{"name":"negative regulation of dendritic extension","type":"related"}],"termid":"GO:2000548"}


id: MONDO:0003538
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm of immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage. Neoplasms involving the bone marrow and the peripheral blood are called precursor lymphoblastic leukemias or acute lymphoblastic leukemias. Neoplasms involving primarily lymph nodes or extranodal sites are called lymphoblastic lymphomas. -- 2003","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lymphoid neoplasm","termid":"MONDO:0005157"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"precursor lymphoblastic lymphoma/leukemia","secondary_identifiers":["NCIT:C7055","DOID:5600","UMLS:C1335469","MEDGEN:235492"],"synonyms":[{"name":"precursor lymphoblastic leukemia/lymphoma","type":"exact"},{"name":"precursor lymphoblastic lymphoma/leukemia","type":"exact"},{"name":"precursor lymphoid neoplasm","type":"exact"}],"termid":"MONDO:0003538","xrefs":{"Monarch":{"xref_id":"0003538"}}}


id: PR:O74493
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC285.05 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74493"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"purine nucleoside permease C285.05 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC285.05","synonyms":[{"name":"Spom972h-SPCC285.05","type":"exact"}],"termid":"PR:O74493"}


id: MONDO:0005256
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Heart failure characterized by marked limitation in activity due to symptoms, even during less-than-ordinary activity, e.g. walking short distances (20b100 m). Patients with moderate heart failure are comfortable only at rest.","definition_xrefs":["EFO:0003148"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symptomatic heart failure","termid":"MONDO:0005254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"moderate heart failure","secondary_identifiers":["Wikipedia:New_York_Heart_Association_Functional_Classification"],"termid":"MONDO:0005256","xrefs":{"Monarch":{"xref_id":"0005256"}}}


id: PBO:0040429
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP6V0E2 antisense RNA 1","termid":"PBO:0040429"}


id: GO:2000761
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein maturation","termid":"GO:1903319"},{"relation_name":"is_a","term_name":"positive regulation of peptidyl-lysine acetylation","termid":"GO:2000758"},{"relation_name":"is_a","term_name":"regulation of N-terminal peptidyl-lysine acetylation","termid":"GO:2000759"},{"relation_name":"positively_regulates","term_name":"N-terminal peptidyl-lysine acetylation","termid":"GO:0018076"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"positively_regulates","termid":"GO:0051604"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0051604"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0051604","GO:0008150"],"is_obsolete":false,"name":"positive regulation of N-terminal peptidyl-lysine acetylation","termid":"GO:2000761"}


id: FYPO:0002789
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed when the population in which the cell is found is in stationary phase in which vacuoles are smaller than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small vacuoles","termid":"FYPO:0002787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"small vacuoles during stationary phase","synonyms":[{"name":"decreased vacuole size during stationary phase","type":"exact"},{"name":"reduced vacuole size during stationary phase","type":"exact"}],"termid":"FYPO:0002789"}


id: MONDO:0019770
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"X-linked intellectual disability-epilepsy syndrome","termid":"MONDO:0016160"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"X-linked dominant intellectual disability-epilepsy syndrome","secondary_identifiers":["Orphanet:93951"],"termid":"MONDO:0019770","xrefs":{"Monarch":{"xref_id":"0019770"}}}


id: MOD:00654
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"a protein modification that effectively replaces a sulfanyl group with a methylsulfanyl group","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methylated residue","termid":"MOD:00427"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"S-methylated residue","synonyms":[{"name":"SMeRes","type":"exact"}],"termid":"MOD:00654"}


id: PBO:0052925
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin associated protein 19-8","termid":"PBO:0052925"}


id: MOD:01039
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"OBSOLETE because redundant and identical to MOD:00036. Remap to MOD:00036.","definition_xrefs":["PubMed:18688235"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE MOD:01039 hydroxy aspartyl (obsolete MOD:01039)","termid":"MOD:01039"}


id: PBO:0055368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2797","termid":"PBO:0055368"}


id: PBO:0089138
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial glutamyl-tRNA amidotransferase beta subunit Gta2","termid":"PBO:0089138"}


id: PBO:0031158
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_tyrosine_import","termid":"PBO:0031158"}


id: SO:1001272
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An intron found in tRNA that is spliced via endonucleolytic cleavage and ligation rather than transesterification.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endonuclease_spliced_intron","termid":"SO:0001216"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA_intron","synonyms":[{"name":"pre-tRNA intron","type":"exact"},{"name":"tRNA intron","type":"exact"}],"termid":"SO:1001272"}


id: GO:0047605
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2.","definition_xrefs":["MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN","EC:4.1.1.5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"acetolactate decarboxylase activity","secondary_identifiers":["RHEA:21580"],"synonyms":[{"name":"(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]","type":"related"},{"name":"(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity","type":"related"},{"name":"alpha-acetolactate decarboxylase activity","type":"related"}],"termid":"GO:0047605"}


id: GO:0019035
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A nucleoprotein complex containing viral genetic material and the viral integrase, required for genome integration into the host's genome. May contain other proteins.","definition_xrefs":["PMID:29900498","PMID:2721960","PMID:21037296"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"host cell","termid":"GO:0043657"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"viral integration complex","secondary_identifiers":["Wikipedia:Pre-integration_complex"],"synonyms":[{"name":"PIC","type":"broad"},{"name":"pre-integration complex","type":"exact"}],"termid":"GO:0019035"}


id: PBO:0038368
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-has_negative_regulatory_component_activity","termid":"PBO:0038368"}


id: GO:0090286
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane.","definition_xrefs":["GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete cytoskeletal anchoring at nuclear membrane (obsolete GO:0090286)","termid":"GO:0090286"}


id: PBO:0062164
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily K member 5","termid":"PBO:0062164"}


id: GO:0014830
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.","definition_xrefs":["MA:0000706","MSH:D001160","GOC:mtg_muscle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"artery smooth muscle contraction","termid":"GO:0014824"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"arteriole smooth muscle contraction","termid":"GO:0014830"}


id: FYPO:0009109
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell growth phenotype in which cell population growth is decreased relative to normal after short incubation in hydroxyurea.","direct_ancestors":[{"relation_name":"is_a","term_name":"decreased vegetative cell population growth","termid":"FYPO:0001355"},{"relation_name":"is_a","term_name":"increased sensitivity to chemical","termid":"FYPO:0002683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002060","FYPO:0002057","FYPO:0001985","FYPO:0002683","FYPO:0002058","FYPO:0000139","FYPO:0000003"],"is_obsolete":false,"name":"decreased vegetative cell population growth after short incubation in hydroxyurea","secondary_identifiers":["PMID:37200372"],"synonyms":[{"name":"decreased vegetative cell population growth after acute hydroxyurea treatment","type":"exact"}],"termid":"FYPO:0009109"}


id: GO:0032438
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.","definition_xrefs":["GOC:vk"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pigment granule organization","termid":"GO:0048753"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"melanosome organization","synonyms":[{"name":"melanosome organisation","type":"exact"},{"name":"melanosome organization and biogenesis","type":"related"}],"termid":"GO:0032438"}


id: PBO:0072610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal L24 domain containing 1 pseudogene 5","termid":"PBO:0072610"}


id: PBO:0083803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential protein that associates with contractile actomyosin ring; required for ingression of the plasma membrane into the bud neck during cytokinesis; C2 domain, a membrane targeting module, is required for function; activates chitin synthase activity of Chs2p during cytokinesis","termid":"PBO:0083803"}


id: PBO:0075868
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SSX family pseudogene 8","termid":"PBO:0075868"}


id: PBO:0034407
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-transcriptionally_regulates_(obsolete_transcriptionally_regulates)","termid":"PBO:0034407"}


id: MONDO:0019465
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nodal marginal zone B-cell lymphoma is a rare, indolent B-cell non-Hodgkin lymphoma, characterized by abnormal clonal proliferation of mature B-lymphocytes with involvement of the lymph nodes, sometimes the bone marrow, and rarely the blood. Clinically it presents with disseminated peripheral, abdominal and/or thoracic lymphadenopathy. Cytopenia and bulky tumors (greater than 5 cm) are rare. Association with Hepatitis C virus and chronic inflammation has been reported.","definition_xrefs":["Orphanet:86867"],"direct_ancestors":[{"relation_name":"is_a","term_name":"marginal zone lymphoma","termid":"MONDO:0017604"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"nodal marginal zone B-cell lymphoma","secondary_identifiers":["ONCOTREE:NMZL","icd11.foundation:1720785883","DOID:0080211","GARD:19075","NCIT:C8863","SCTID:277623009","UMLS:C0855139","MEDGEN:208959","MedDRA:10029460"],"synonyms":[{"name":"Monocytoid B-cell lymphoma","type":"exact"},{"name":"NMZL","type":"exact"},{"name":"nodal marginal zone B-cell lymph.","type":"exact"},{"name":"nodal marginal zone B-cell lymphoma","type":"exact"},{"name":"nodal marginal zone lymphoma","type":"exact"}],"termid":"MONDO:0019465","xrefs":{"Monarch":{"xref_id":"0019465"}}}


id: GO:0097495
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes.","definition_xrefs":["PMID:21600204","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"cytosol","termid":"GO:0005829"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005829"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005829","GO:0005737","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"H-NS-Hha complex","termid":"GO:0097495"}


id: PBO:0072887
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SH3 domain binding kinase family member 2","termid":"PBO:0072887"}


id: GO:0048642
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of striated muscle tissue development","termid":"GO:0045843"},{"relation_name":"is_a","term_name":"regulation of skeletal muscle tissue development","termid":"GO:0048641"},{"relation_name":"negatively_regulates","term_name":"skeletal muscle tissue development","termid":"GO:0007519"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of skeletal muscle tissue development","synonyms":[{"name":"down regulation of skeletal muscle development","type":"exact"},{"name":"down-regulation of skeletal muscle development","type":"exact"},{"name":"downregulation of skeletal muscle development","type":"exact"},{"name":"inhibition of skeletal muscle development","type":"narrow"}],"termid":"GO:0048642"}


id: MONDO:0018057
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete toxocariasis (obsolete MONDO:0018057)","termid":"MONDO:0018057","xrefs":{"Monarch":{"xref_id":"0018057"}}}


id: PR:O42954
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mbx1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42954"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MADS-box transcription factor 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC19G7.06","synonyms":[{"name":"Spom972h-mbx1","type":"exact"}],"termid":"PR:O42954"}


id: GO:0043635
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.","definition_xrefs":["PMID:16535687","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xenobiotic catabolic process","termid":"GO:0042178"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"methylnaphthalene catabolic process","synonyms":[{"name":"1-MN catabolic process","type":"related"},{"name":"1-MN catabolism","type":"related"},{"name":"1-methylnaphthalene catabolic process","type":"narrow"},{"name":"1-methylnaphthalene catabolism","type":"narrow"},{"name":"2-MN catabolic process","type":"related"},{"name":"2-MN catabolism","type":"related"},{"name":"2-methylnaphthalene catabolic process","type":"narrow"},{"name":"2-methylnaphthalene catabolism","type":"narrow"}],"termid":"GO:0043635"}


id: GO:1903908
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization.","definition_xrefs":["GOC:als","GOC:TermGenie","PMID:23575248","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cellular component organization","termid":"GO:0051130"},{"relation_name":"is_a","term_name":"regulation of plasma membrane raft polarization","termid":"GO:1903906"},{"relation_name":"positively_regulates","term_name":"plasma membrane raft polarization","termid":"GO:0044858"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0061024"},{"rel_name":"regulates","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0008150","GO:0061024"],"is_obsolete":false,"name":"positive regulation of plasma membrane raft polarization","synonyms":[{"name":"activation of plasma membrane raft polarization","type":"narrow"},{"name":"up regulation of plasma membrane raft polarization","type":"exact"},{"name":"up-regulation of plasma membrane raft polarization","type":"exact"},{"name":"upregulation of plasma membrane raft polarization","type":"exact"}],"termid":"GO:1903908"}


id: GO:0035665
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.","definition_xrefs":["GOC:BHF","PMID:12447441"],"direct_ancestors":[{"relation_name":"is_a","term_name":"toll-like receptor 4 signaling pathway","termid":"GO:0034142"},{"relation_name":"is_a","term_name":"TIRAP-dependent toll-like receptor signaling pathway","termid":"GO:0035664"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"TIRAP-dependent toll-like receptor 4 signaling pathway","synonyms":[{"name":"MAL-dependent toll-like receptor 4 signaling pathway","type":"exact"},{"name":"MyD88 adapter-like dependent toll-like receptor 4 signaling pathway","type":"exact"},{"name":"TIRAP-dependent TLR4 signaling pathway","type":"exact"},{"name":"TIRAP-dependent toll-like receptor 4 signalling pathway","type":"exact"}],"termid":"GO:0035665"}


id: GO:0031818
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a P2Y9 nucleotide receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled nucleotide receptor binding","termid":"GO:0031811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"P2Y9 nucleotide receptor binding","synonyms":[{"name":"P2Y9 nucleotide receptor ligand","type":"narrow"}],"termid":"GO:0031818"}


id: MOD:00499
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Chemical derivative","definition_xrefs":["PubMed:3578767","Unimod:128#C","PubMed:3311742"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"},{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"5-iodoacetamidofluorescein","synonyms":[{"name":"5-Iodoacetamidofluorescein (Molecular Probe, Eugene, OR)","type":"related"},{"name":"Fluorescein","type":"related"}],"termid":"MOD:00499"}


id: GO:1905063
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.","definition_xrefs":["PMID:19088079","GO_REF:0000058","GOC:rph","GOC:BHF","GOC:TermGenie","GOC:BHF_miRNA"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of smooth muscle cell differentiation","termid":"GO:0051150"},{"relation_name":"regulates","term_name":"vascular associated smooth muscle cell differentiation","termid":"GO:0035886"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of vascular associated smooth muscle cell differentiation","synonyms":[{"name":"regulation of VSMC differentiation","type":"exact"},{"name":"regulation of vascular smooth muscle cell differentiation","type":"exact"}],"termid":"GO:1905063"}


id: PBO:0041871
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium sensing receptor","termid":"PBO:0041871"}


id: GO:0052398
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The activation by an organism of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete induction by organism of symbiont phytoalexin production (obsolete GO:0052398)","synonyms":[{"name":"activation by organism of symbiont phytoalexin production","type":"exact"},{"name":"induction by organism of symbiont phytoalexin production","type":"exact"}],"termid":"GO:0052398"}


id: GO:0031270
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The myosin-based contraction and retraction of a pseudopodium.","definition_xrefs":["GOC:pg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component disassembly","termid":"GO:0022411"},{"relation_name":"is_a","term_name":"pseudopodium organization","termid":"GO:0031268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pseudopodium retraction","termid":"GO:0031270"}


id: GO:1900865
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any RNA modification that takes place in chloroplast.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA modification","termid":"GO:0009451"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"chloroplast RNA modification","synonyms":[{"name":"RNA editing in chloroplast","type":"narrow"}],"termid":"GO:1900865"}


id: MONDO:0020920
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infection with the organism Escherichia Coli.","definition_xrefs":["NCIT:C34594"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial infectious disease","termid":"MONDO:0005113"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"escherichia coli infection","secondary_identifiers":["MEDGEN:4543","MESH:D004927","GTR:AN0485754","UMLS:C0014836","HP:0002740","GTR:AN0485755","SCTID:71057007","EFO:1001318","GTR:AN0474198"],"synonyms":[{"name":"Bacterial infection caused by E. coli","type":"related"},{"name":"Bacterial infection due to E. coli","type":"related"},{"name":"Colibacillosis","type":"related"},{"name":"E COLI INFECT","type":"related"},{"name":"E Coli Infection","type":"related"},{"name":"E coli Infection","type":"related"},{"name":"E coli Infections","type":"related"},{"name":"E coli infections","type":"related"},{"name":"E coli infections, recurrent","type":"related"},{"name":"E. coli Infection","type":"related"},{"name":"E. coli Infections","type":"related"},{"name":"E. coli infection","type":"related"},{"name":"ESCHERICHIA COLI INFECT","type":"related"},{"name":"Escherichia Coli Infection","type":"related"},{"name":"Escherichia coli Infection","type":"related"},{"name":"Escherichia coli Infections","type":"related"},{"name":"Escherichia coli infection","type":"related"},{"name":"INFECT E COLI","type":"related"},{"name":"INFECT ESCHERICHIA COLI","type":"related"},{"name":"Infection caused by Escherichia coli","type":"related"},{"name":"Infection due to Escherichia coli","type":"related"},{"name":"Infection, E coli","type":"related"},{"name":"Infection, E. coli","type":"related"},{"name":"Infection, Escherichia coli","type":"related"},{"name":"Infections, E coli","type":"related"},{"name":"Infections, Escherichia coli","type":"related"},{"name":"Recurrent E. coli infections","type":"related"},{"name":"e coli infection","type":"exact"},{"name":"escherichia coli infection","type":"exact"}],"termid":"MONDO:0020920","xrefs":{"Monarch":{"xref_id":"0020920"}}}


id: GO:0051034
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA transmembrane transporter activity","termid":"GO:0051033"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"tRNA transmembrane transporter activity","termid":"GO:0051034"}


id: GO:1903807
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol.","definition_xrefs":["GOC:TermGenie","GO_REF:0000075","PMID:23895341"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic cation transport","termid":"GO:0015695"},{"relation_name":"is_a","term_name":"threonine transport","termid":"GO:0015826"},{"relation_name":"is_a","term_name":"amino acid import across plasma membrane","termid":"GO:0089718"},{"relation_name":"is_a","term_name":"L-alpha-amino acid transmembrane transport","termid":"GO:1902475"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179","GO:0055085"],"is_obsolete":false,"name":"L-threonine import across plasma membrane","secondary_identifiers":["GO:0036231"],"synonyms":[{"name":"L-threonine import","type":"broad"},{"name":"L-threonine import into cell","type":"exact"},{"name":"L-threonine uptake","type":"exact"}],"termid":"GO:1903807"}


id: MONDO:1011045
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nephritis that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nephritis, non-human animal","termid":"MONDO:1010259"},{"relation_name":"is_a","term_name":"renal disease, dog","termid":"MONDO:1012235"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nephritis, dog","secondary_identifiers":["OMIA:000708-9615"],"termid":"MONDO:1011045","xrefs":{"Monarch":{"xref_id":"1011045"}}}


id: PBO:0113447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit l of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; more abundant in the ATP synthase monomer; involved in the calcium-induced permeability transition and calcium homeostasis; does not impact ATP synthase activity and stability; N-terminal region has sequence similarity to Atp19p; conserved in A. gossypii; detected in highly purified mitochondria in high-throughput studies","termid":"PBO:0113447"}


id: PBO:0087518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin","termid":"PBO:0087518"}


id: PBO:0050510
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homeobox C10","termid":"PBO:0050510"}


id: PBO:0001774
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MutS protein homolog 3","termid":"PBO:0001774"}


id: PBO:0068619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U2 small nuclear 71, pseudogene","termid":"PBO:0068619"}


id: MONDO:0003071
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete epidermolysis bullosa simplex (obsolete MONDO:0003071)","termid":"MONDO:0003071","xrefs":{"Monarch":{"xref_id":"0003071"}}}


id: MONDO:0008031
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any facioscapulohumeral muscular dystrophy in which the cause of the disease is a mutation in the SMCHD1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"facioscapulohumeral muscular dystrophy","termid":"MONDO:0001347"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0019303"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0019303"],"is_obsolete":false,"name":"facioscapulohumeral muscular dystrophy 2","secondary_identifiers":["NCIT:C172705","OMIM:158901","UMLS:C1834671","DOID:0111193","MEDGEN:320405","GARD:15088","MESH:C563557"],"synonyms":[{"name":"FSHD2","type":"related"},{"name":"Fshd2, digenic","type":"related"},{"name":"SMCHD1 facioscapulohumeral muscular dystrophy","type":"exact"},{"name":"facioscapulohumeral muscular dystrophy 2","type":"exact"},{"name":"facioscapulohumeral muscular dystrophy 2, digenic","type":"related"},{"name":"facioscapulohumeral muscular dystrophy caused by mutation in SMCHD1","type":"exact"},{"name":"facioscapulohumeral muscular dystrophy type 2","type":"exact"},{"name":"fascioscapulohumeral muscular dystrophy 2, digenic, digenic dominant","type":"exact"},{"name":"muscular dystrophy, facioscapulohumeral, type 1B","type":"related"},{"name":"muscular dystrophy, facioscapulohumeral, type 2","type":"related"}],"termid":"MONDO:0008031","xrefs":{"Monarch":{"xref_id":"0008031"}}}


id: GO:0004641
data:
  {"annotated_genes":["SJAG_03140"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71012],"is_not":false,"summary":null,"term":"GO:0004641"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H+ + phosphate.","definition_xrefs":["EC:6.3.3.1","RHEA:23032"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cyclo-ligase activity","termid":"GO:0016882"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03140":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016874"],"is_obsolete":false,"name":"phosphoribosylformylglycinamidine cyclo-ligase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["KEGG_REACTION:R04208","Reactome:R-HSA-73810","MetaCyc:AIRS-RXN"],"synonyms":[{"name":"2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)","type":"related"},{"name":"2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)","type":"related"},{"name":"5'-aminoimidazole ribonucleotide synthetase activity","type":"related"},{"name":"AIR synthase activity","type":"related"},{"name":"AIR synthetase activity","type":"related"},{"name":"AIRS activity","type":"related"},{"name":"phosphoribosyl-aminoimidazole synthetase activity","type":"related"},{"name":"phosphoribosylaminoimidazole synthetase activity","type":"related"}],"termid":"GO:0004641","terms_by_termid":{"GO:0004641":null}}


id: PBO:0046017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 2 alpha kinase 3","termid":"PBO:0046017"}


id: GO:0008135
data:
  {"annotated_genes":["SJAG_02704"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[62188],"is_not":false,"summary":null,"term":"GO:0008135"}]},"cv_name":"molecular_function","definition":"Functions during translation by binding to RNA during polypeptide synthesis at the ribosome.","definition_xrefs":["GOC:vw","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"translation factor activity","termid":"GO:0180051"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02704":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674"],"is_obsolete":false,"name":"translation factor activity, RNA binding","references_by_uniquename":{"GO_REF:0000117":null},"synonyms":[{"name":"translation factor activity, nucleic acid binding","type":"broad"}],"termid":"GO:0008135","terms_by_termid":{"GO:0008135":null}}


id: MONDO:0018011
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Juvenile overlap myositis is a rare juvenile idiopathic inflammatory myopathy characterized by the association of inflammatory myositis (manifesting with acral erythema, progressive weakness of the limbs, pain, general fatigue, moodiness or crankiness) with clinical and/or laboratory features of other autoimmune diseases (e.g. systemic lupus erythematosus, localized scleroderma, diabetes). Cardiac involvement has been reported in some patients.","definition_xrefs":["Orphanet:329894"],"direct_ancestors":[{"relation_name":"is_a","term_name":"juvenile idiopathic inflammatory myopathy","termid":"MONDO:0018010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336"],"is_obsolete":false,"name":"juvenile overlap myositis","secondary_identifiers":["GARD:21497","UMLS:C4707728","MEDGEN:1634026","SCTID:766252004"],"termid":"MONDO:0018011","xrefs":{"Monarch":{"xref_id":"0018011"}}}


id: MOD:01072
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes one potassium atom for one hydrogen atom.","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"potassium containing modified residue","termid":"MOD:00849"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monopotassium salt","synonyms":[{"name":"K1Res","type":"exact"}],"termid":"MOD:01072"}


id: PBO:0061125
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NLR family pyrin domain containing 14","termid":"PBO:0061125"}


id: PBO:0091967
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cut Eight suppressing Kinase","termid":"PBO:0091967"}


id: PBO:0040128
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and SOCS box containing 14","termid":"PBO:0040128"}


