# terms

id: GO:0018639
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.","definition_xrefs":["UM-BBD_enzymeID:e0172"],"gene_count":0,"genotype_count":0,"name":"obsolete xylene monooxygenase activity (obsolete GO:0018639)","termid":"GO:0018639"}


id: PBO:0090030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA cleavage and polyadenylation specificity factor complex, WD repeat protein Cft1","termid":"PBO:0090030"}


id: PBO:0090535
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NatC N-acetyltransferase complex catalytic subunit Naa30","termid":"PBO:0090535"}


id: MONDO:0007480
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dwarfism with stiff joints and ocular abnormalities","secondary_identifiers":["UMLS:C0265349","MEDGEN:82709","SCTID:72913007","ICD9:759.89","MESH:C535724","OMIM:127200","Orphanet:2569"],"synonyms":[{"name":"Moore-Federman syndrome","type":"related"},{"name":"dwarfism with stiff joints and ocular abnormalities","type":"exact"}],"termid":"MONDO:0007480","xrefs":{"Monarch":{"xref_id":"0007480"}}}


id: FYPO:0006509
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which telomere length is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal telomere morphology","termid":"FYPO:0006508"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0000641"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000293"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000641","FYPO:0001985","FYPO:0000293","FYPO:0005447"],"is_obsolete":false,"name":"abnormal telomere length","termid":"FYPO:0006509"}


id: PBO:0086242
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that localizes to the mitochondrial intermembrane space; localizes via the Mia40p-Erv1p system; contains twin cysteine-x(9)-cysteine motifs","termid":"PBO:0086242"}


id: PBO:0003477
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial translation termination factor Rrf1","termid":"PBO:0003477"}


id: GO:0048293
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of isotype switching","termid":"GO:0045191"},{"relation_name":"regulates","term_name":"isotype switching to IgE isotypes","termid":"GO:0048289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0006310"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006259","GO:0006310","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of isotype switching to IgE isotypes","synonyms":[{"name":"regulation of class switch recombination to IgE isotypes","type":"exact"},{"name":"regulation of class switching to IgE isotypes","type":"exact"},{"name":"regulation of isotype switch recombination to IgE isotypes","type":"exact"}],"termid":"GO:0048293"}


id: PBO:0085437
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; also binds single-stranded telomeric repeat sequence in vitro; relocalizes to the cytosol in response to hypoxia; GBP2 has a paralog, HRB1, that arose from the whole genome duplication","termid":"PBO:0085437"}


id: MONDO:0007681
data:
  {"annotated_genes":["SJAG_03689"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87062],"is_not":false,"summary":null,"term":"MONDO:0007681"}]},"cv_name":"mondo","definition":"Any multinodular goiter in which the cause of the disease is a mutation in the DICER1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multinodular goiter","termid":"MONDO:0000334"},{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"},{"relation_name":"is_a","term_name":"DICER1-related tumor predisposition","termid":"MONDO:0100216"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03689":null},"genotype_count":0,"is_obsolete":false,"name":"goiter, multinodular 1, with or without Sertoli-Leydig cell tumors","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:C562732","GARD:17278","ICD9:240.0","MEDGEN:86230","OMIM:138800","Orphanet:276399","UMLS:C0302859","SCTID:267369002"],"synonyms":[{"name":"FMNG","type":"exact"},{"name":"MNG1","type":"exact"},{"name":"euthyroid goiter","type":"broad"},{"name":"euthyroid goitre","type":"broad"},{"name":"familial MNG","type":"exact"},{"name":"goiter, multinodular 1, with or without Sertoli-Leydig cell tumors","type":"exact"},{"name":"goiter, nontoxic, with Intrathyroidal calcification","type":"exact"},{"name":"multinodular goiter, adolescent","type":"exact"},{"name":"simple goiter","type":"broad"},{"name":"simple goitre","type":"broad"}],"termid":"MONDO:0007681","terms_by_termid":{"MONDO:0007681":null},"xrefs":{"Monarch":{"xref_id":"0007681"}}}


id: MONDO:0006648
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Rapid swelling, increased tension, pain, and ischemic necrosis of the muscles of the anterior tibial compartment of the leg, often following excessive physical exertion.","definition_xrefs":["MESH:D000868"],"direct_ancestors":[{"relation_name":"is_a","term_name":"compartment syndrome","termid":"MONDO:0004001"},{"relation_name":"is_a","term_name":"skeletal muscle disorder","termid":"MONDO:0020120"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anterior compartment of tibia syndrome","secondary_identifiers":["UMLS:C0003152","MEDGEN:1569","SCTID:12694001","DOID:3933"],"synonyms":[{"name":"anterior compartment syndrome","type":"exact"}],"termid":"MONDO:0006648","xrefs":{"Monarch":{"xref_id":"0006648"}}}


id: GO:0070066
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).","definition_xrefs":["PMID:11839770"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SNARE complex","termid":"GO:0031201"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"cellubrevin-VAMP4-endobrevin-syntaxin-6 complex","synonyms":[{"name":"SNARE complex (Vamp3, Vamp4, Vam8, Stx6)","type":"narrow"},{"name":"Vamp3-Vamp4-Vam8-Stx6 complex","type":"narrow"}],"termid":"GO:0070066"}


id: FYPO:0004120
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which a spore germinates to produce an inviable cell that is smaller than normal, has a septum with abnormal size, shape, or structure, and that undergoes two or more rounds of cell division, and then dies.","definition_xrefs":["PMID:15116432","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable after spore germination, multiple cell divisions, elongated cell","termid":"FYPO:0002262"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000004","FYPO:0001320","FYPO:0000005","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"inviable after spore germination, multiple cell divisions, small cell with abnormal septum morphology","synonyms":[{"name":"inviable after spore germination, multiple cell divisions, small cell with abnormal septum formation","type":"exact"},{"name":"inviable following spore germination, multiple cell divisions, small cell with abnormal septum morphology","type":"exact"},{"name":"inviable germinated spore, multiple cell divisions, small cell with abnormal septum morphology","type":"exact"},{"name":"lethal after spore germination, multiple cell divisions, small cell with abnormal septum morphology","type":"exact"}],"termid":"FYPO:0004120"}


id: MONDO:0017101
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"isolated focal cortical dysplasia type II","termid":"MONDO:0011818"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022"],"is_obsolete":false,"name":"isolated focal cortical dysplasia type IIa","secondary_identifiers":["GARD:17270","Orphanet:269001","MEDGEN:375876","NANDO:1200568","UMLS:C1846386"],"synonyms":[{"name":"FCD type IIa","type":"exact"}],"termid":"MONDO:0017101","xrefs":{"Monarch":{"xref_id":"0017101"}}}


id: GO:1990674
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex.","definition_xrefs":["PMID:24119662","PMID:16038056","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Golgi cisterna membrane","termid":"GO:0032580"},{"relation_name":"part_of","term_name":"Golgi cis cisterna","termid":"GO:0000137"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005794"}],"interesting_parent_ids":["GO:0005737","GO:0005794","GO:0005575"],"is_obsolete":false,"name":"Golgi cis cisterna membrane","synonyms":[{"name":"Golgi apparatus cis cisterna membrane","type":"exact"},{"name":"cis-Golgi cisterna membrane","type":"exact"}],"termid":"GO:1990674"}


id: PBO:0091995
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tfb6 annotation seems tenuous, SGD have not annotated","termid":"PBO:0091995"}


id: MONDO:0024546
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any primary hypertrophic osteoarthropathy in which the cause of the disease is a mutation in the HPGD gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"primary hypertrophic osteoarthropathy","termid":"MONDO:0016620"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypertrophic osteoarthropathy, primary, autosomal recessive, 1","secondary_identifiers":["GARD:15216","MEDGEN:1641972","OMIM:259100","UMLS:C4551679"],"synonyms":[{"name":"Cranioosteoarthropathy","type":"related"},{"name":"Currarino idiopathic osteoarthropathy","type":"related"},{"name":"HPGD primary hypertrophic osteoarthropathy","type":"exact"},{"name":"PDP, autosomal recessive","type":"related"},{"name":"PHOAR1","type":"related"},{"name":"Pho, autosomal recessive","type":"related"},{"name":"Touraine-Solente-Gole syndrome","type":"related"},{"name":"familial idiopathic osteoarthropathy of childhood","type":"related"},{"name":"hypertrophic osteoarthropathy, primary, autosomal recessive 1","type":"exact"},{"name":"hypertrophic osteoarthropathy, primary, autosomal recessive, 1","type":"exact"},{"name":"pachydermoperiostosis, autosomal recessive","type":"related"},{"name":"primary hypertrophic osteoarthropathy caused by mutation in HPGD","type":"exact"}],"termid":"MONDO:0024546","xrefs":{"Monarch":{"xref_id":"0024546"}}}


id: GO:0001541
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.","direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"female gonad development","termid":"GO:0008585"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ovarian follicle development","synonyms":[{"name":"follicular phase","type":"related"}],"termid":"GO:0001541"}


id: GO:0047488
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.","definition_xrefs":["MetaCyc:4.2.2.7-RXN","EC:4.2.2.7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-oxygen lyase activity, acting on polysaccharides","termid":"GO:0016837"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"heparin lyase activity","synonyms":[{"name":"heparan sulfate lyase activity","type":"related"},{"name":"heparin eliminase activity","type":"related"},{"name":"heparinase activity","type":"related"}],"termid":"GO:0047488"}


id: PBO:0041690
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcitonin pseudogene","termid":"PBO:0041690"}


id: PR:Q09920
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fio1 gene.","definition_xrefs":["UniProtKB:Q09920","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iron transport multicopper oxidase fio1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1F7.08","synonyms":[{"name":"Spom972h-fio1","type":"exact"}],"termid":"PR:Q09920"}


id: PBO:0070207
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 134 pseudogene","termid":"PBO:0070207"}


id: PBO:0087212
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S-adenosylmethionine-dependent protein methyltransferase; capable of automethylation; member of the seven beta-strand family; YNL092W is not an essential gene","termid":"PBO:0087212"}


id: PBO:0113390
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; located in the upstream region of PMA1; conserved among S. cerevisiae strains; mediates the cycloheximide-induced degradation of ubiquitinated Agp2p, a regulator of high affinity polyamine and carnitine transport; null mutant is polyamine resistant due to downregulation of PMA1","termid":"PBO:0113390"}


id: PBO:0062864
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"OTU deubiquitinase 1","termid":"PBO:0062864"}


id: GO:0062171
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of lutein.","definition_xrefs":["PMID:24397433"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xanthophyll biosynthetic process","termid":"GO:0016123"},{"relation_name":"is_a","term_name":"lutein metabolic process","termid":"GO:0062170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"lutein biosynthetic process","synonyms":[{"name":"lutein anabolism","type":"exact"},{"name":"lutein biosynthesis","type":"exact"},{"name":"lutein formation","type":"exact"}],"termid":"GO:0062171"}


id: GO:0033530
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oligosaccharide metabolic process","termid":"GO:0009311"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"raffinose metabolic process","synonyms":[{"name":"raffinose metabolism","type":"exact"}],"termid":"GO:0033530"}


id: PBO:0087419
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit 8 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p","termid":"PBO:0087419"}


id: MONDO:1010296
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Marfan syndrome that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"connective tissue disorder, non-human animal","termid":"MONDO:1011309"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"musculoskeletal system disorder, non-human animal","termid":"MONDO:1011335"},{"relation_name":"is_a","term_name":"syndromic disease, non-human animal","termid":"MONDO:1011360"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Marfan syndrome, non-human animal","secondary_identifiers":["OMIA:000628"],"termid":"MONDO:1010296","xrefs":{"Monarch":{"xref_id":"1010296"}}}


id: GO:0035459
data:
  {"annotated_genes":["SJAG_03153","SJAG_01381","SJAG_05345","SJAG_03558","SJAG_02349","SJAG_02539","SJAG_00072","SJAG_05344"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[100029],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0035652"},{"annotations":[75163,76023,71720,77436,78782,76847,75394],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090110"}]},"cv_name":"biological_process","definition":"The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.","definition_xrefs":["GOC:lb","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transport","termid":"GO:0006810"},{"relation_name":"part_of","term_name":"vesicle-mediated transport","termid":"GO:0016192"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00072":null,"SJAG_01381":null,"SJAG_02349":null,"SJAG_02539":null,"SJAG_03153":null,"SJAG_03558":null,"SJAG_05344":null,"SJAG_05345":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0016192","GO:0006810"],"is_obsolete":false,"name":"vesicle cargo loading","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"cargo loading into vesicle","type":"exact"},{"name":"cargo selection","type":"exact"}],"termid":"GO:0035459","terms_by_termid":{"GO:0035652":null,"GO:0090110":null}}


id: GO:0140952
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.","definition_xrefs":["RHEA:64452"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone H3K27 methyltransferase activity","termid":"GO:0046976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0008276"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0008276","GO:0016741","GO:0140096","GO:0003674"],"is_obsolete":false,"name":"histone H3K27 dimethyltransferase activity","secondary_identifiers":["EC:2.1.1.371"],"synonyms":[{"name":"histone H3-K27 dimethylase activity","type":"exact"},{"name":"histone H3-K27 dimethylation","type":"broad"},{"name":"histone H3K27 dimethylase activity","type":"exact"},{"name":"histone H3K27 dimethylation","type":"broad"},{"name":"histone H3K27 mono/dimethylase activity","type":"exact"},{"name":"histone lysine N-dimethyltransferase activity (H3-K27 specific)","type":"exact"}],"termid":"GO:0140952"}


id: MONDO:0012863
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"excluded_subClassOf","term_name":"attention deficit-hyperactivity disorder","termid":"MONDO:0007743"},{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"attention deficit-hyperactivity disorder, susceptibility to, 6","secondary_identifiers":["OMIM:612312","UMLS:C2676740","MEDGEN:393577"],"synonyms":[{"name":"ADHD6","type":"exact"},{"name":"attention Deficit-hyperactivity disorder, susceptibility to, type 6","type":"exact"},{"name":"attention deficit-hyperactivity disorder, susceptibility to, 6","type":"exact"},{"name":"digit span quantitative trait locus","type":"related"}],"termid":"MONDO:0012863","xrefs":{"Monarch":{"xref_id":"0012863"}}}


id: PR:O13874
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC1B3.09c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13874"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized NOC2 family protein C1B3.09c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1B3.09c","synonyms":[{"name":"Spom972h-SPAC1B3.09c","type":"exact"}],"termid":"PR:O13874"}


id: PBO:0055668
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat and Ig domain containing 4","termid":"PBO:0055668"}


id: PBO:0005756
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L15 (predicted)","termid":"PBO:0005756"}


id: MONDO:0010363
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any non-syndromic X-linked intellectual disability in which the cause of the disease is a mutation in the ZDHHC15 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability, X-linked 91","secondary_identifiers":["MESH:C564482","MEDGEN:375592","OMIM:300577","DOID:0112043","UMLS:C1845142"],"synonyms":[{"name":"MRX91","type":"related"},{"name":"ZDHHC15 non-syndromic X-linked intellectual disability","type":"exact"},{"name":"intellectual disability, X-linked 91","type":"exact"},{"name":"intellectual disability, X-linked type 91","type":"exact"},{"name":"mental retardation, X-linked 91","type":"related"},{"name":"mental retardation, X-linked 91, X-linked dominant","type":"exact"},{"name":"mental retardation, X-linked type 91","type":"exact"},{"name":"non-syndromic X-linked intellectual disability caused by mutation in ZDHHC15","type":"exact"}],"termid":"MONDO:0010363","xrefs":{"Monarch":{"xref_id":"0010363"}}}


id: GO:0046300
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.","definition_xrefs":["UM-BBD_pathwayID:2,4-d","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"2,4-dichlorophenoxyacetic acid metabolic process","termid":"GO:0018901"},{"relation_name":"is_a","term_name":"monocarboxylic acid catabolic process","termid":"GO:0072329"},{"relation_name":"is_a","term_name":"ether catabolic process","termid":"GO:1901502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"2,4-dichlorophenoxyacetic acid catabolic process","secondary_identifiers":["UM-BBD_pathwayID:2\\,4-d"],"synonyms":[{"name":"2,4-dichlorophenoxyacetic acid breakdown","type":"exact"},{"name":"2,4-dichlorophenoxyacetic acid catabolism","type":"exact"},{"name":"2,4-dichlorophenoxyacetic acid degradation","type":"exact"}],"termid":"GO:0046300"}


id: FYPO:0007227
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal in centromeric regions.","definition_xrefs":["PomBase:mah","PMID:31822915"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased number of R-loops","termid":"FYPO:0007901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased number of R-loops at centromere","synonyms":[{"name":"increased RNA-DNA hybrid level at centromere","type":"exact"},{"name":"increased level of DNA:RNA hybrids at centromere","type":"exact"},{"name":"increased level of RNA-DNA hybrids at centromere","type":"exact"},{"name":"increased level of RNA-DNA hybrids at centromere during mitotic cell cycle","type":"related"},{"name":"increased level of RNA-DNA hybrids at centromere during vegetative growth","type":"exact"}],"termid":"FYPO:0007227"}


id: PBO:0076154
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SURP and G-patch domain containing 2","termid":"PBO:0076154"}


id: PBO:0055095
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2513","termid":"PBO:0055095"}


id: GO:0043923
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host-mediated perturbation of symbiont process","termid":"GO:0051851"},{"relation_name":"positively_regulates","term_name":"viral transcription","termid":"GO:0019083"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation by host of viral transcription","synonyms":[{"name":"positive regulation of viral transcription by host","type":"exact"}],"termid":"GO:0043923"}


id: PBO:0056110
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LYPLA2 pseudogene 1","termid":"PBO:0056110"}


id: PBO:0000213
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Chs Four Homologue","termid":"PBO:0000213"}


id: PBO:0047306
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FARSB pseudogene 1","termid":"PBO:0047306"}


id: GO:0051393
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.","definition_xrefs":["PMID:10984498","PMID:11699871","PMID:15014165"],"direct_ancestors":[{"relation_name":"is_a","term_name":"actinin binding","termid":"GO:0042805"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008092"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0008092","GO:0005488"],"is_obsolete":false,"name":"alpha-actinin binding","secondary_identifiers":["GO:0051372"],"synonyms":[{"name":"alpha-actinin 1 binding","type":"narrow"},{"name":"alpha-actinin 4 binding","type":"narrow"},{"name":"nonmuscle alpha-actinin binding","type":"narrow"}],"termid":"GO:0051393"}


id: MONDO:0009935
data:
  {"annotated_genes":["SJAG_03866","SJAG_04757"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86986,86987],"is_not":false,"summary":null,"term":"MONDO:0009935"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"primary pulmonary hypertension","termid":"MONDO:0001999"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03866":null,"SJAG_04757":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"pulmonary hypertension, primary, autosomal recessive","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:265400","MESH:C564862","MEDGEN:1802382","UMLS:C5676877"],"synonyms":[{"name":"pulmonary hypertension, primary, autosomal recessive","type":"exact"}],"termid":"MONDO:0009935","terms_by_termid":{"MONDO:0009935":null},"xrefs":{"Monarch":{"xref_id":"0009935"}}}


id: MONDO:0024415
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"duodenitis","termid":"MONDO:0004627"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"hemorrhagic duodenitis","secondary_identifiers":["UMLS:C0341245","MEDGEN:137951","ICD9:535.61","SCTID:95531001"],"synonyms":[{"name":"erosive duodenitis","type":"related"},{"name":"hemorrhagic duodenitis","type":"exact"},{"name":"multiple duodenal erosions","type":"related"}],"termid":"MONDO:0024415","xrefs":{"Monarch":{"xref_id":"0024415"}}}


id: PATO:0000897
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000897 germ line dependent fertility value (obsolete PATO:0000897)","termid":"PATO:0000897"}


id: PBO:0079856
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unc-93 homolog B5 (pseudogene)","termid":"PBO:0079856"}


id: SO:0001136
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Right handed type I:A motif of four consecutive residues that may contain one H-bond, which, if present, is between the main-chain CO of the first residue and the main-chain NH of the fourth. It is characterized by the dihedral angles: Residue(i+1): -140 degrees < phi < -20 degrees, -90 degrees < psi < +40 degrees. Residue(i+2): -140 degrees < phi < -20 degrees, -90 degrees < psi < +40 degrees.","definition_xrefs":["EBIBS:GAR"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta_turn","termid":"SO:0001133"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"beta_turn_right_handed_type_one","secondary_identifiers":["BS:00216"],"synonyms":[{"name":"beta turn right handed type one","type":"exact"},{"name":"beta_turn_ir","type":"exact"},{"name":"type I beta turn","type":"exact"},{"name":"type I turn","type":"exact"}],"termid":"SO:0001136"}


id: GO:0050440
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H+.","definition_xrefs":["RHEA:23780"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyltransferase activity, acyl groups converted into alkyl on transfer","termid":"GO:0046912"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0016746","GO:0003824"],"is_obsolete":false,"name":"2-methylcitrate synthase activity","secondary_identifiers":["MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN","EC:2.3.3.5","KEGG_REACTION:R00931"],"synonyms":[{"name":"2-methylcitrate oxaloacetate-lyase activity","type":"related"},{"name":"MCS activity","type":"related"},{"name":"methylcitrate synthase activity","type":"related"},{"name":"methylcitrate synthetase activity","type":"related"},{"name":"propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)","type":"related"}],"termid":"GO:0050440"}


id: GO:1902405
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any actomyosin contractile ring localization that is involved in mitotic cell cycle.","definition_xrefs":["GOC:TermGenie","GOC:mtg_cell_cycle"],"gene_count":0,"genotype_count":0,"name":"obsolete mitotic actomyosin contractile ring localization (obsolete GO:1902405)","termid":"GO:1902405"}


id: PBO:0084272
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Integral membrane protein; localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p; SKG6 has a paralog, TOS2, that arose from the whole genome duplication","termid":"PBO:0084272"}


id: PBO:0042260
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chaperonin containing TCP1 subunit 4 pseudogene 2","termid":"PBO:0042260"}


id: GO:0140549
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The membrane surrounding the spore core (endospore core) that separates it from its external environment.","definition_xrefs":["PMID:23202530"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane","termid":"GO:0016020"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"spore inner membrane","synonyms":[{"name":"spore membrane","type":"broad"}],"termid":"GO:0140549"}


id: PBO:0067448
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 570, pseudogene","termid":"PBO:0067448"}


id: PBO:0017443
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-regulated_by","termid":"PBO:0017443"}


id: PBO:0076057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stomatin like 3","termid":"PBO:0076057"}


id: PBO:0048853
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucosamine (N-acetyl)-6-sulfatase","termid":"PBO:0048853"}


id: PR:Q09768
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A glutamate--cysteine ligase catalytic subunit that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11164:SF0","OMA:SCHPO00267","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamate--cysteine ligase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22F3.10c","secondary_identifiers":["UniProtKB:Q09768"],"synonyms":[{"name":"GCS (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-GCLC","type":"exact"},{"name":"gamma-ECS (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"gamma-glutamylcysteine synthetase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q09768"}


id: MONDO:0012302
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"parietal foramina","termid":"MONDO:0018953"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0020022"}],"interesting_parent_ids":["MONDO:0020022"],"is_obsolete":false,"name":"parietal foramina 3","secondary_identifiers":["MEDGEN:322792","OMIM:609566","UMLS:C1835980","GARD:18052","MESH:C563697"],"synonyms":[{"name":"PFM3","type":"exact"},{"name":"parietal foramina 3","type":"exact"}],"termid":"MONDO:0012302","xrefs":{"Monarch":{"xref_id":"0012302"}}}


id: GO:1990523
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regrowth of bone following its loss or destruction.","definition_xrefs":["PMID:25257467"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tissue regeneration","termid":"GO:0042246"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"bone regeneration","termid":"GO:1990523"}


id: PBO:0030786
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-elongated_aseptate_vegetative_cell","termid":"PBO:0030786"}


id: FYPO:0002190
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"swollen spheroid vegetative cell","termid":"FYPO:0000945"},{"relation_name":"is_a","term_name":"inviable swollen vegetative cell with abnormal cell shape","termid":"FYPO:0002415"},{"relation_name":"is_a","term_name":"inviable spheroid vegetative cell","termid":"FYPO:0002482"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000005","FYPO:0001320","FYPO:0000004","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"inviable swollen spheroid vegetative cell","synonyms":[{"name":"inviable enlarged spheroid vegetative cell","type":"related"},{"name":"inviable enlarged volume spheroid vegetative cell","type":"exact"},{"name":"inviable large spheroid vegetative cell","type":"related"},{"name":"inviable swollen rounded vegetative cell","type":"exact"},{"name":"inviable swollen spheroid cell during vegetative growth","type":"exact"},{"name":"inviable swollen spheroid vegetative cell during mitotic cell cycle","type":"related"},{"name":"inviable, increased spheroid vegetative cell size","type":"related"},{"name":"inviable, increased spheroid vegetative cell volume","type":"exact"},{"name":"lethal; swollen spheroid vegetative cell","type":"exact"}],"termid":"FYPO:0002190"}


id: MOD:01540
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Applied Biosystems iTRAQ8plex-114 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"iTRAQ8plex-114 reporter+balance reagent acylated residue","termid":"MOD:01535"},{"relation_name":"is_a","term_name":"iTRAQ8plex reporter+balance reagent O-acylated residue","termid":"MOD:01714"},{"relation_name":"is_a","term_name":"O3-acylated L-serine","termid":"MOD:02003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ8plex-114 reporter+balance reagent O3-acylated serine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"}],"termid":"MOD:01540"}


id: GO:0048871
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.","definition_xrefs":["GOC:isa_complete"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multicellular organismal process","termid":"GO:0032501"},{"relation_name":"is_a","term_name":"homeostatic process","termid":"GO:0042592"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"multicellular organismal-level homeostasis","termid":"GO:0048871"}


id: MONDO:0008243
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare neurodegenerative disorder leading to dementia. It is characterized by frontotemporal lobar degeneration with accumulation of tau proteins which form Pick bodies.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"frontotemporal dementia","termid":"MONDO:0017276"},{"relation_name":"is_a","term_name":"cerebral degeneration","termid":"MONDO:0024238"},{"relation_name":"is_a","term_name":"cerebral cortex disorder","termid":"MONDO:0044996"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0002039","MONDO:0005559"],"is_obsolete":false,"name":"Pick disease","secondary_identifiers":["UMLS:C0236642","ICD10CM:G31.01","ICD9:331.11","MEDGEN:116020","NCIT:C85008","DOID:11870","MESH:D020774","EFO:0003096","SCTID:13092008","OMIM:172700"],"synonyms":[{"name":"PICK disease of brain","type":"exact"},{"name":"Pick disease","type":"exact"},{"name":"Pick disease of the brain","type":"related"},{"name":"Pick's disease","type":"related"},{"name":"dementia in Pick's disease","type":"exact"},{"name":"dementia with lobar atrophy and neuronal cytoplasmic inclusions","type":"related"},{"name":"lobar atrophy of brain","type":"exact"},{"name":"lobar atrophy of the brain","type":"related"}],"termid":"MONDO:0008243","xrefs":{"Monarch":{"xref_id":"0008243"}}}


id: MONDO:0011714
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome","secondary_identifiers":["UMLS:C3807567","GARD:18038","OMIM:606721","MEDGEN:813897"],"synonyms":[{"name":"LCCNS","type":"related"},{"name":"lipodystrophy, familial partial, type 7","type":"exact"},{"name":"lipodystrophy, partial, with congenital cataracts and neurodegeneration","type":"related"},{"name":"partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome","type":"exact"}],"termid":"MONDO:0011714","xrefs":{"Monarch":{"xref_id":"0011714"}}}


id: PBO:0090764
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Wiskott-Aldrich syndrome homolog binding protein Lsb1","termid":"PBO:0090764"}


id: PBO:0051740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"integrator complex subunit 7","termid":"PBO:0051740"}


id: PBO:0066301
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"retinol binding protein 3","termid":"PBO:0066301"}


id: PBO:0061559
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NT5DC1 pseudogene 2","termid":"PBO:0061559"}


id: MONDO:0006694
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Atherosclerosis of the cerebral vasculature.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"atherosclerosis","termid":"MONDO:0005311"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebral atherosclerosis","secondary_identifiers":["MESH:D002537","SCTID:55382008","ICD9:437.0","MedDRA:1008095","NCIT:C34459","DOID:12720","ICD10CM:I67.2","EFO:1000860","icd11.foundation:1710003414","UMLS:C0007775","MEDGEN:40189"],"synonyms":[{"name":"cerebral atherosclerosis","type":"exact"}],"termid":"MONDO:0006694","xrefs":{"Monarch":{"xref_id":"0006694"}}}


id: PBO:0083407
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif","termid":"PBO:0083407"}


id: PBO:0052173
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium two pore domain channel subfamily K member 4","termid":"PBO:0052173"}


id: PBO:0028740
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-L-ergothioneine_absent_from_cell","termid":"PBO:0028740"}


id: MOD:01089
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DeltaMass","termid":"MOD:00947"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"xanthyl","synonyms":[{"name":"Xan","type":"exact"}],"termid":"MOD:01089"}


id: GO:0120231
data:
  {"annotated_genes":["SJAG_04950","SJAG_03751"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[79262,88821],"is_not":false,"summary":null,"term":"GO:0120231"}]},"cv_name":"cellular_component","definition":"A protein complex that binds to a recombinase and incrseases its activity.","definition_xrefs":["PMID:32414915"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme activator complex","termid":"GO:0150005"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03751":null,"SJAG_04950":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"DNA recombinase auxiliary factor complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"DNA recombinase accessory factor complex","type":"exact"},{"name":"DNA recombinase activator complex","type":"exact"}],"termid":"GO:0120231","terms_by_termid":{"GO:0120231":null}}


id: PBO:0083437
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOL036W","termid":"PBO:0083437"}


id: PBO:0077344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 86A","termid":"PBO:0077344"}


id: PBO:0031334
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_cadmium","termid":"PBO:0031334"}


id: GO:1901319
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of catabolic process","termid":"GO:0009896"},{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"is_a","term_name":"positive regulation of carbohydrate metabolic process","termid":"GO:0045913"},{"relation_name":"is_a","term_name":"regulation of trehalose metabolic process","termid":"GO:0090062"},{"relation_name":"positively_regulates","term_name":"trehalose catabolic process","termid":"GO:0005993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"positive regulation of trehalose catabolic process","synonyms":[{"name":"activation of mycose catabolic process","type":"exact"},{"name":"activation of mycose catabolism","type":"exact"},{"name":"activation of mykose catabolic process","type":"exact"},{"name":"activation of mykose catabolism","type":"exact"},{"name":"activation of trehalose breakdown","type":"exact"},{"name":"activation of trehalose catabolic process","type":"narrow"},{"name":"activation of trehalose catabolism","type":"exact"},{"name":"activation of trehalose degradation","type":"exact"},{"name":"positive regulation of mycose catabolic process","type":"exact"},{"name":"positive regulation of mycose catabolism","type":"exact"},{"name":"positive regulation of mykose catabolic process","type":"exact"},{"name":"positive regulation of mykose catabolism","type":"exact"},{"name":"positive regulation of trehalose breakdown","type":"exact"},{"name":"positive regulation of trehalose catabolism","type":"exact"},{"name":"positive regulation of trehalose degradation","type":"exact"},{"name":"up regulation of mycose catabolic process","type":"exact"},{"name":"up regulation of mycose catabolism","type":"exact"},{"name":"up regulation of mykose catabolic process","type":"exact"},{"name":"up regulation of mykose catabolism","type":"exact"},{"name":"up regulation of trehalose breakdown","type":"exact"},{"name":"up regulation of trehalose catabolic process","type":"exact"},{"name":"up regulation of trehalose catabolism","type":"exact"},{"name":"up regulation of trehalose degradation","type":"exact"},{"name":"up-regulation of mycose catabolic process","type":"exact"},{"name":"up-regulation of mycose catabolism","type":"exact"},{"name":"up-regulation of mykose catabolic process","type":"exact"},{"name":"up-regulation of mykose catabolism","type":"exact"},{"name":"up-regulation of trehalose breakdown","type":"exact"},{"name":"up-regulation of trehalose catabolic process","type":"exact"},{"name":"up-regulation of trehalose catabolism","type":"exact"},{"name":"up-regulation of trehalose degradation","type":"exact"},{"name":"upregulation of mycose catabolic process","type":"exact"},{"name":"upregulation of mycose catabolism","type":"exact"},{"name":"upregulation of mykose catabolic process","type":"exact"},{"name":"upregulation of mykose catabolism","type":"exact"},{"name":"upregulation of trehalose breakdown","type":"exact"},{"name":"upregulation of trehalose catabolic process","type":"exact"},{"name":"upregulation of trehalose catabolism","type":"exact"},{"name":"upregulation of trehalose degradation","type":"exact"}],"termid":"GO:1901319"}


id: GO:0004992
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with platelet activating factor to initiate a change in cell activity.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor activity","termid":"GO:0004930"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"platelet activating factor receptor activity","synonyms":[{"name":"PAF receptor activity","type":"exact"}],"termid":"GO:0004992"}


id: GO:0019902
data:
  {"annotated_genes":["SJAG_04638","SJAG_03793"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73305],"is_not":false,"summary":null,"term":"GO:0019902"},{"annotations":[63634],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019903"}]},"cv_name":"molecular_function","definition":"Binding to a phosphatase.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme binding","termid":"GO:0019899"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03793":null,"SJAG_04638":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"phosphatase binding","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"termid":"GO:0019902","terms_by_termid":{"GO:0019902":null,"GO:0019903":null}}


id: PBO:0062709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 51 subfamily H member 1","termid":"PBO:0062709"}


id: GO:0099513
data:
  {"annotated_genes":["SJAG_01196","SJAG_01297","SJAG_02045","SJAG_02695","SJAG_02040","SJAG_01330","SJAG_02509","SJAG_01224","SJAG_03540","SJAG_00113","SJAG_03264","SJAG_01546","SJAG_00030","SJAG_01837","SJAG_00845","SJAG_03088","SJAG_03145","SJAG_01775","SJAG_02566","SJAG_01993","SJAG_04841","SJAG_00773","SJAG_04887","SJAG_04003","SJAG_02336","SJAG_02624","SJAG_04387","SJAG_00930","SJAG_02286","SJAG_03052","SJAG_01613","SJAG_01215","SJAG_00851","SJAG_00918","SJAG_05266","SJAG_03073","SJAG_04745","SJAG_00655","SJAG_00140","SJAG_05220","SJAG_00723","SJAG_02761","SJAG_02651","SJAG_00332","SJAG_00594"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[76053,95615,71889,109360,76967],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005884"},{"annotations":[104324,107730,112432,107521,99528],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000235"},{"annotations":[99529,98935,108551,91714,104194,101737],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0055028"},{"annotations":[97895,104057,95536],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1903754"},{"annotations":[91485,104852,105179,118435,113066],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005881"},{"annotations":[97596],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0062194"},{"annotations":[114343,89958,118948,104196,97299,100686,102632],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1904511"},{"annotations":[88093],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990574"},{"annotations":[119644,97094,74186,68412],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005874"},{"annotations":[100689,99534],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0036449"},{"annotations":[104963,119497,79816,70968,80247,99536],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0035371"},{"annotations":[79249,108557,91718],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061673"},{"annotations":[97302],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1905721"},{"annotations":[107810],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990941"},{"annotations":[101742,106631,118954,100691],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990498"},{"annotations":[99539,98939,107811,118441],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990537"},{"annotations":[91721],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005880"},{"annotations":[101745,95107],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005827"},{"annotations":[97303,101746],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905759"},{"annotations":[91723],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1905760"},{"annotations":[90086,77398,104010,63235,76684,76114,100841],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005876"}]},"cv_name":"cellular_component","definition":"A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"supramolecular fiber","termid":"GO:0099512"},{"relation_name":"part_of","term_name":"cytoskeleton","termid":"GO:0005856"}],"gene_count":45,"genes_by_uniquename":{"SJAG_00030":null,"SJAG_00113":null,"SJAG_00140":null,"SJAG_00332":null,"SJAG_00594":null,"SJAG_00655":null,"SJAG_00723":null,"SJAG_00773":null,"SJAG_00845":null,"SJAG_00851":null,"SJAG_00918":null,"SJAG_00930":null,"SJAG_01196":null,"SJAG_01215":null,"SJAG_01224":null,"SJAG_01297":null,"SJAG_01330":null,"SJAG_01546":null,"SJAG_01613":null,"SJAG_01775":null,"SJAG_01837":null,"SJAG_01993":null,"SJAG_02040":null,"SJAG_02045":null,"SJAG_02286":null,"SJAG_02336":null,"SJAG_02509":null,"SJAG_02566":null,"SJAG_02624":null,"SJAG_02651":null,"SJAG_02695":null,"SJAG_02761":null,"SJAG_03052":null,"SJAG_03073":null,"SJAG_03088":null,"SJAG_03145":null,"SJAG_03264":null,"SJAG_03540":null,"SJAG_04003":null,"SJAG_04387":null,"SJAG_04745":null,"SJAG_04841":null,"SJAG_04887":null,"SJAG_05220":null,"SJAG_05266":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"polymeric cytoskeletal fiber","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"PMID:21802294":null,"PMID:30726171":null},"termid":"GO:0099513","terms_by_termid":{"GO:0000235":null,"GO:0005827":null,"GO:0005874":null,"GO:0005876":null,"GO:0005880":null,"GO:0005881":null,"GO:0005884":null,"GO:0035371":null,"GO:0036449":null,"GO:0055028":null,"GO:0061673":null,"GO:0062194":null,"GO:1903754":null,"GO:1904511":null,"GO:1905721":null,"GO:1905759":null,"GO:1905760":null,"GO:1990498":null,"GO:1990537":null,"GO:1990574":null,"GO:1990941":null}}


id: FYPO:0007836
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at subtelomeric regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes.","definition_xrefs":["PomBase:mah","PMID:31837996"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nucleosome positioning in heterochromatin","termid":"FYPO:0000855"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000641","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"increased nucleosome occupancy at subtelomere","synonyms":[{"name":"increased nucleosome occupancy at subtelomere during mitotic cell cycle","type":"related"},{"name":"increased nucleosome occupancy at subtelomere during vegetative growth","type":"exact"}],"termid":"FYPO:0007836"}


id: MONDO:0015655
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete cerebral malformation with epilepsy (obsolete MONDO:0015655)","secondary_identifiers":["Orphanet:166478"],"termid":"MONDO:0015655","xrefs":{"Monarch":{"xref_id":"0015655"}}}


id: RO:0002615
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Inverse of is-model-of","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_model","termid":"RO:0002615"}


id: MONDO:0019169
data:
  {"annotated_genes":["SJAG_03553","SJAG_03290","SJAG_03064","SJAG_02158","SJAG_00866","SJAG_03310","SJAG_02006"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86997],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013762"},{"annotations":[86792],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010717"},{"annotations":[86278],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013580"},{"annotations":[87126],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009502"},{"annotations":[85566],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009529"},{"annotations":[87127],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009503"},{"annotations":[86790],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012120"}]},"cv_name":"mondo","definition":"A rare neurometabolic disorder characterized by a wide range of clinical signs with metabolic and neurological components of varying severity. Manifestations range from often fatal, severe, neonatal lactic acidosis to later-onset neurological disorders. Six subtypes related to the affected subunit of the PDH complex have been recognized with significant clinical overlap: PDHD due to E1-alpha, E1-beta, E2 and E3 deficiency, PDHD due to E3-binding protein deficiency, and PDH phosphatase deficiency.","definition_xrefs":["Orphanet:765"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"metabolic epilepsy","termid":"MONDO:0100033"},{"relation_name":"is_a","term_name":"inborn mitochondrial metabolism disorder","termid":"MONDO:0004069"},{"relation_name":"is_a","term_name":"pyruvate metabolism disorder","termid":"MONDO:0016789"},{"relation_name":"is_a","term_name":"inborn carbohydrate metabolic disorder","termid":"MONDO:0019214"},{"relation_name":"is_a","term_name":"hereditary peripheral neuropathy","termid":"MONDO:0020127"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00866":null,"SJAG_02006":null,"SJAG_02158":null,"SJAG_03064":null,"SJAG_03290":null,"SJAG_03310":null,"SJAG_03553":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0004069","MONDO:0005066","MONDO:0005244"],"is_obsolete":false,"name":"pyruvate dehydrogenase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C103968","OMIMPS:312170","icd11.foundation:1124597954","SCTID:46683007","GARD:7513","UMLS:C0034345","NORD:1641","DOID:3649","ICD9:277.89","MEDGEN:19610","NANDO:2200518"],"synonyms":[{"name":"PDH","type":"exact"},{"name":"PDHC","type":"exact"},{"name":"Pyruvate Dehydrogenase Complex Deficiency","type":"exact"},{"name":"deficiency of pyruvic dehydrogenase","type":"exact"},{"name":"pyruvate decarboxylase deficiency","type":"exact"},{"name":"pyruvate dehydrogenase complex deficiency","type":"exact"},{"name":"pyruvate dehydrogenase complex deficiency disease","type":"exact"},{"name":"pyruvate dehydrogenase deficiency","type":"exact"}],"termid":"MONDO:0019169","terms_by_termid":{"MONDO:0009502":null,"MONDO:0009503":null,"MONDO:0009529":null,"MONDO:0010717":null,"MONDO:0012120":null,"MONDO:0013580":null,"MONDO:0013762":null},"xrefs":{"Monarch":{"xref_id":"0019169"}}}


id: FYPO:0003547
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured in a cell is greater than normal. The number, extent, or both of damage sites may be increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased DNA damage","termid":"FYPO:0003546"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002"],"is_obsolete":false,"name":"increased DNA damage during vegetative growth","synonyms":[{"name":"increased DNA damage during mitotic cell cycle","type":"related"},{"name":"increased number of DNA lesions during vegetative growth","type":"related"},{"name":"increased spontaneous DNA lesions during vegetative growth","type":"related"}],"termid":"FYPO:0003547"}


id: GO:0070660
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.","definition_xrefs":["PMID:19381250","GOC:dsf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inner ear receptor cell differentiation","termid":"GO:0060113"},{"relation_name":"is_a","term_name":"mechanoreceptor differentiation involved in mechanosensory epithelium regeneration","termid":"GO:0070656"},{"relation_name":"part_of","term_name":"inner ear sensory epithelium regeneration","termid":"GO:0070659"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration","termid":"GO:0070660"}


id: GO:1901113
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving erythromycin.","definition_xrefs":["GOC:TermGenie","GOC:yaf","UniPathway:UPA00240"],"direct_ancestors":[{"relation_name":"is_a","term_name":"macrolide metabolic process","termid":"GO:0033067"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"erythromycin metabolic process","synonyms":[{"name":"erythromycin metabolism","type":"exact"}],"termid":"GO:1901113"}


id: PBO:0081206
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZKSCAN7 ZNF cluster antisense RNA 1","termid":"PBO:0081206"}


id: PBO:0004307
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"target of chaperonin-containing T-complex","termid":"PBO:0004307"}


id: PBO:0080504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WAPL cohesin release factor","termid":"PBO:0080504"}


id: PBO:0080096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UST antisense RNA 2","termid":"PBO:0080096"}


id: PATO:0000817
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000817 anosmia (obsolete PATO:0000817)","termid":"PATO:0000817"}


id: MONDO:0010450
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability, X-linked 89","secondary_identifiers":["DOID:0112031","MEDGEN:333247","MESH:C564036","GARD:22688","OMIM:300848","UMLS:C1839082"],"synonyms":[{"name":"MRX89","type":"exact"},{"name":"intellectual disability, X-linked 89","type":"exact"},{"name":"mental retardation, X-linked 89","type":"related"},{"name":"mental retardation, X-linked 89, X-linked dominant","type":"exact"}],"termid":"MONDO:0010450","xrefs":{"Monarch":{"xref_id":"0010450"}}}


id: PBO:0003291
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ferric-chelate reductase Frp2 (predicted)","termid":"PBO:0003291"}


id: GO:1904163
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of triglyceride homeostasis.","definition_xrefs":["GOC:BHF","GO_REF:0000058","GOC:rph","PMID:22541436","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of triglyceride homeostasis (obsolete GO:1904163)","synonyms":[{"name":"regulation of triacylglycerol homeostasis","type":"exact"}],"termid":"GO:1904163"}


id: MOD:01420
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that crosslinks two residues by condensation of a cysteine thiol with the carbonyl of the preceding residue to form a thiazole or thiazoline ring.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thioether crosslinked residues","termid":"MOD:00687"},{"relation_name":"is_a","term_name":"oxazole/thiazole ring crosslinked residues","termid":"MOD:00690"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"thiazole/thiazoline ring crosslinked residues","termid":"MOD:01420"}


id: PATO:0002014
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"structure","termid":"PATO:0000141"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"structure, cavities","termid":"PATO:0002014"}


id: PBO:0075504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spermatogenesis associated serine rich 2","termid":"PBO:0075504"}


id: PATO:0001398
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A cellular quality inhering in a bearer by virtue of the bearer's having the ability to go through numerous cycles of cell division while maintaining the undifferentiated state.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proliferative","termid":"PATO:0002102"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"self-renewal","termid":"PATO:0001398"}


id: PATO:0001189
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A maturity quality inhering in a bearer by virtue of the bearer's being between the onset of puberty and maturity.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"maturity","termid":"PATO:0000261"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adolescent","termid":"PATO:0001189"}


id: PBO:0001434
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EB1 family Mal3","termid":"PBO:0001434"}


id: FYPO:0000204
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of mRNA from the nucleus is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal RNA localization during vegetative growth","termid":"FYPO:0000360"},{"relation_name":"is_a","term_name":"abnormal nuclear export","termid":"FYPO:0000506"},{"relation_name":"is_a","term_name":"abnormal metabolic process during vegetative growth","termid":"FYPO:0001363"},{"relation_name":"is_a","term_name":"RNA transport phenotype","termid":"FYPO:0004852"},{"relation_name":"is_a","term_name":"abnormal gene expression","termid":"FYPO:0006551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0006551","FYPO:0001320","FYPO:0000138","FYPO:0001985"],"is_obsolete":false,"name":"abnormal mRNA export from nucleus","synonyms":[{"name":"abnormal mRNA export from nucleus during mitotic cell cycle","type":"related"},{"name":"abnormal mRNA export from nucleus during vegetative growth","type":"exact"}],"termid":"FYPO:0000204"}


id: PBO:0090750
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial metalloendopeptidase","termid":"PBO:0090750"}


id: PBO:0029921
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cellular_squalene_level","termid":"PBO:0029921"}


id: PBO:0065859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAB17, member RAS oncogene family","termid":"PBO:0065859"}


id: PBO:0057464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 583","termid":"PBO:0057464"}


id: PBO:0052355
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin family member 5B","termid":"PBO:0052355"}


id: MOD:01760
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-131 reporter+balance group.","definition_xrefs":["Unimod:737"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"cysTMT6plex-131 reporter+balance reagent cysteine disulfide","termid":"MOD:01828"},{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent acylated residue","termid":"MOD:01715"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-131 reporter+balance reagent acylated residue","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"},{"name":"cysTMT6plex-131 reporter fragment","type":"exact"}],"termid":"MOD:01760"}


id: PBO:0042159
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C-C motif chemokine ligand 20","termid":"PBO:0042159"}


id: GO:0052640
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.","definition_xrefs":["MetaCyc:RXN-11658","RHEA:62312"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016757"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0016757","GO:0003674"],"is_obsolete":false,"name":"salicylic acid glucosyltransferase (glucoside-forming) activity","synonyms":[{"name":"UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (glucoside-forming) activity","type":"exact"},{"name":"UDP:glucose:SA glucosyltransferase (glucoside-forming) activity","type":"exact"},{"name":"UDP:glucose:salicylate glucosyltransferase (glucoside-forming) activity","type":"exact"},{"name":"UDP:glucose:salicylic acid glucosyltransferase (glucoside-forming) activity","type":"exact"},{"name":"salicylic acid glucosyltransferase activity","type":"broad"}],"termid":"GO:0052640"}


id: GO:0016627
data:
  {"annotated_genes":["SJAG_04652","SJAG_00174","SJAG_02876","SJAG_03240","SJAG_02291","SJAG_02717","SJAG_04944","SJAG_02007","SJAG_01671","SJAG_02151","SJAG_00203","SJAG_03024","SJAG_01041","SJAG_03236","SJAG_01362","SJAG_04810","SJAG_01786","SJAG_04107","SJAG_00197","SJAG_04954","SJAG_00260"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[62633],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003865"},{"annotations":[80274],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004109"},{"annotations":[80660],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0050613"},{"annotations":[80670],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000246"},{"annotations":[57231],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106430"},{"annotations":[59925],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004318"},{"annotations":[95348],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0141148"},{"annotations":[73437],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016156"},{"annotations":[118722,105010,89800,109940],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106414"},{"annotations":[67769,58736],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016628"},{"annotations":[72902],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004729"},{"annotations":[61697],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0160198"},{"annotations":[61704],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102389"},{"annotations":[77146],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043115"},{"annotations":[79129],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008977"},{"annotations":[68106],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004665"},{"annotations":[66479,76361],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008177"},{"annotations":[111632],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019166"},{"annotations":[109941],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102262"},{"annotations":[109942],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102263"},{"annotations":[105011],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102264"},{"annotations":[118723],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102266"},{"annotations":[118724],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102267"},{"annotations":[66145],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102265"}]},"cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.","definition_xrefs":["EC:1.3.-.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity","termid":"GO:0016491"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00174":null,"SJAG_00197":null,"SJAG_00203":null,"SJAG_00260":null,"SJAG_01041":null,"SJAG_01362":null,"SJAG_01671":null,"SJAG_01786":null,"SJAG_02007":null,"SJAG_02151":null,"SJAG_02291":null,"SJAG_02717":null,"SJAG_02876":null,"SJAG_03024":null,"SJAG_03236":null,"SJAG_03240":null,"SJAG_04107":null,"SJAG_04652":null,"SJAG_04810":null,"SJAG_04944":null,"SJAG_04954":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"oxidoreductase activity, acting on the CH-CH group of donors","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000003":null,"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-2995334","Reactome:R-HSA-9661710"],"synonyms":[{"name":"oxidoreductase activity, acting on the CH-CH group of donors, other acceptors","type":"narrow"}],"termid":"GO:0016627","terms_by_termid":{"GO:0000246":null,"GO:0003865":null,"GO:0004109":null,"GO:0004318":null,"GO:0004665":null,"GO:0004729":null,"GO:0008177":null,"GO:0008977":null,"GO:0016156":null,"GO:0016628":null,"GO:0019166":null,"GO:0043115":null,"GO:0050613":null,"GO:0102262":null,"GO:0102263":null,"GO:0102264":null,"GO:0102265":null,"GO:0102266":null,"GO:0102267":null,"GO:0102389":null,"GO:0106414":null,"GO:0106430":null,"GO:0141148":null,"GO:0160198":null}}


id: PBO:0078013
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 3","termid":"PBO:0078013"}


id: PBO:0005712
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rRNA processing protein Utp23 (predicted)","termid":"PBO:0005712"}


id: GO:0098948
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.","definition_xrefs":["GOC:mah","GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete intrinsic component of postsynaptic specialization membrane (obsolete GO:0098948)","synonyms":[{"name":"intrinsic to postsynaptic specialization membrane","type":"narrow"}],"termid":"GO:0098948"}


id: PBO:0057452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 571","termid":"PBO:0057452"}


id: GO:0001198
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.","definition_xrefs":["GOC:txnOH"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of mating-type specific transcription from RNA polymerase II promoter (obsolete GO:0001198)","synonyms":[{"name":"down regulation of RNA polymerase II transcription, mating-type specific","type":"exact"},{"name":"down-regulation of RNA polymerase II transcription, mating-type specific","type":"exact"},{"name":"downregulation of RNA polymerase II transcription, mating-type specific","type":"exact"},{"name":"inhibition of RNA polymerase II transcription, mating-type specific","type":"narrow"}],"termid":"GO:0001198"}


id: PBO:0079752
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uridine-cytidine kinase 1 like 1","termid":"PBO:0079752"}


id: GO:0044805
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM.","definition_xrefs":["GOC:dgf","GOC:jl","PMID:22768199"],"gene_count":0,"genotype_count":0,"name":"obsolete late nucleophagy (obsolete GO:0044805)","termid":"GO:0044805"}


id: MONDO:0002009
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An episode of depression lasting two or more weeks without an intervening episode of mania.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"depressive disorder","termid":"MONDO:0002050"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"major depressive disorder","secondary_identifiers":["SCTID:370143000","UMLS:C1269683","ICD9:296.2","ICD9:296.3","ICD9:296.30","MEDGEN:266123","NCIT:C35094","SCTID:300706003","MFOMD:0000143","MESH:D003865","ICD9:296.20","DOID:1470","OMIM:608516","EFO:0003761"],"synonyms":[{"name":"major depression","type":"exact"},{"name":"major depressive disorder","type":"exact"},{"name":"major depressive disorder 1","type":"broad"},{"name":"major depressive disorder 2","type":"broad"},{"name":"major depressive disorder and accelerated response to antidepressant drug treatment","type":"exact"},{"name":"major depressive disorder, response to citalopram therapy in","type":"exact"},{"name":"recurrent major depression","type":"exact"},{"name":"single major depressive episode","type":"exact"},{"name":"unipolar depression","type":"exact"},{"name":"unipolar depression, susceptibility to","type":"exact"}],"termid":"MONDO:0002009","xrefs":{"Monarch":{"xref_id":"0002009"}}}


id: GO:0039643
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The region of a host cell that contains the viral genome.","definition_xrefs":["GOC:bf","GOC:bm","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host intracellular part","termid":"GO:0033646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host cell viral nucleoid","termid":"GO:0039643"}


id: GO:0036184
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.","definition_xrefs":["GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"asperthecin metabolic process","termid":"GO:0036182"},{"relation_name":"is_a","term_name":"ketone biosynthetic process","termid":"GO:0042181"},{"relation_name":"is_a","term_name":"secondary metabolite biosynthetic process","termid":"GO:0044550"},{"relation_name":"is_a","term_name":"phenol-containing compound biosynthetic process","termid":"GO:0046189"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0019748","GO:0008150"],"is_obsolete":false,"name":"asperthecin biosynthetic process","synonyms":[{"name":"asperthecin biosynthesis","type":"exact"},{"name":"asperthecin formation","type":"exact"},{"name":"asperthecin synthesis","type":"exact"}],"termid":"GO:0036184"}


id: SO:0000518
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"Genomic DNA of immunoglobulin/T-cell receptor gene in rearranged configuration including at least one V-gene and one DJ-gene.","direct_ancestors":[{"relation_name":"has_part","term_name":"V_gene_segment","termid":"SO:0000466"},{"relation_name":"has_part","term_name":"DJ_gene_segment","termid":"SO:0000572"},{"relation_name":"is_a","term_name":"vertebrate_immunoglobulin_T_cell_receptor_rearranged_gene_cluster","termid":"SO:0000938"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V_DJ_cluster","synonyms":[{"name":"V DJ cluster","type":"exact"},{"name":"V-(DJ)-CLUSTER","type":"exact"}],"termid":"SO:0000518"}


id: MONDO:0032806
data:
  {"annotated_genes":["SJAG_01235"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87329],"is_not":false,"summary":null,"term":"MONDO:0032806"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"trichothiodystrophy","termid":"MONDO:0018053"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01235":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"trichothiodystrophy 7, nonphotosensitive","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1684762","NCIT:C173102","UMLS:C5231403","GARD:16362","DOID:0111870","OMIM:618546"],"synonyms":[{"name":"TRICHOTHIODYSTROPHY 7, NONPHOTOSENSITIVE","type":"related"},{"name":"TTD7","type":"related"}],"termid":"MONDO:0032806","terms_by_termid":{"MONDO:0032806":null},"xrefs":{"Monarch":{"xref_id":"0032806"}}}


id: GO:0097219
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement.","definition_xrefs":["POC:curators","ISBN:0471738433"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sieve plate","termid":"GO:0097218"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005618"}],"interesting_parent_ids":["GO:0005618","GO:0005575"],"is_obsolete":false,"name":"compound sieve plate","termid":"GO:0097219"}


id: MOD:00599
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces one hydrogen atom with one methyl group.","definition_xrefs":["PubMed:11875433","Unimod:34"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methylated residue","termid":"MOD:00427"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00427"}],"interesting_parent_ids":["MOD:00427"],"is_obsolete":false,"name":"monomethylated residue","synonyms":[{"name":"Me1Res","type":"exact"},{"name":"Methyl","type":"related"},{"name":"Methylation","type":"related"}],"termid":"MOD:00599"}


id: MOD:01376
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-isoleucine residue to a (2S,3S,4R)-3,4-dihydroxyisoleucine.","definition_xrefs":["PubMed:11320328","RESID:AA0447","ChEBI:141827"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dihydroxylated isoleucine","termid":"MOD:01416"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"(2S,3S,4R)-3,4-dihydroxyisoleucine","synonyms":[{"name":"(2S,3S,4R)-2-amino-3,4-dihydroxy-3-methylpentanoic acid","type":"exact"},{"name":"(2S,3S,4R)-3,4-dihydroxyisoleucine","type":"exact"},{"name":"(3S,4R)-3,4-dihydroxyisoleucine","type":"exact"},{"name":"MOD_RES (3S,4R)-3,4-dihydroxyisoleucine","type":"exact"},{"name":"beta,gamma-dihydroxyisoleucine","type":"exact"}],"termid":"MOD:01376"}


id: PBO:0110051
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial tranlagtion factor Sls1","termid":"PBO:0110051"}


id: PBO:0082280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Anti-silencing protein; causes derepression of silent loci when overexpressed","termid":"PBO:0082280"}


id: GO:0070318
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of G0 to G1 transition","termid":"GO:0070316"},{"relation_name":"is_a","term_name":"positive regulation of cell cycle process","termid":"GO:0090068"},{"relation_name":"positively_regulates","term_name":"G0 to G1 transition","termid":"GO:0045023"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"positively_regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"positive regulation of G0 to G1 transition","termid":"GO:0070318"}


id: MONDO:0005689
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Physical and psychological dependence on the drug cannabis.","definition_xrefs":["NCIT:C34445"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"substance abuse","termid":"MONDO:0002491"},{"relation_name":"excluded_subClassOf","term_name":"hallucinogen dependence","termid":"MONDO:0004939"},{"relation_name":"is_a","term_name":"drug dependence","termid":"MONDO:0005303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cannabis dependence","secondary_identifiers":["DOID:1849","SCTID:37344009","MESH:D002189","ICD9:304.30","ICD9:305.2","DOID:9505","EFO:0007191","icd11.foundation:1129015467","ICD9:304.3","MEDGEN:14303","SCTID:85005007","UMLS:C0006870"],"synonyms":[{"name":"cannabis abuse","type":"exact"},{"name":"marijuana abuse","type":"exact"},{"name":"marijuana dependence","type":"exact"}],"termid":"MONDO:0005689","xrefs":{"Monarch":{"xref_id":"0005689"}}}


id: GO:2000874
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of glyoxylate cycle.","definition_xrefs":["GOC:dgf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate metabolic process","termid":"GO:0006109"},{"relation_name":"is_a","term_name":"regulation of ketone metabolic process","termid":"GO:0010565"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"glyoxylate cycle","termid":"GO:0006097"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0005975"],"is_obsolete":false,"name":"regulation of glyoxylate cycle","synonyms":[{"name":"regulation of glyoxylate bypass","type":"exact"}],"termid":"GO:2000874"}


id: GO:0004939
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.","definition_xrefs":["GOC:cb","GOC:mah","IUPHAR_GPCR:1274"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adrenergic receptor activity","termid":"GO:0004935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"beta-adrenergic receptor activity","synonyms":[{"name":"beta adrenoceptor","type":"exact"}],"termid":"GO:0004939"}


id: PBO:0113399
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; localizes to cytosol and peroxisomes; similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2","termid":"PBO:0113399"}


id: MONDO:0018110
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete lethal idiopathic viral infection (obsolete MONDO:0018110)","secondary_identifiers":["Orphanet:35064"],"termid":"MONDO:0018110","xrefs":{"Monarch":{"xref_id":"0018110"}}}


id: MONDO:0021905
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Apert-like polydactyly syndrome","synonyms":[{"name":"Apert like polydactyly syndrome","type":"related"}],"termid":"MONDO:0021905","xrefs":{"Monarch":{"xref_id":"0021905"}}}


id: MONDO:0015737
data:
  {"annotated_genes":["SJAG_03379","SJAG_03025","SJAG_03145"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85642],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008070"},{"annotations":[87074],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009725"},{"annotations":[86219],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012538"}]},"cv_name":"mondo","definition":"Typical nemaline myopathy is a moderate neonatal form of nemaline myopathy (NM) characterized by facial and skeletal muscle weakness and mild respiratory involvement.","definition_xrefs":["Orphanet:171436"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of alpha-actin","termid":"MONDO:0016193"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of nebulin","termid":"MONDO:0016194"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of tropomyosin","termid":"MONDO:0017303"},{"relation_name":"is_a","term_name":"nemaline myopathy","termid":"MONDO:0018958"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":3,"genes_by_uniquename":{"SJAG_03025":null,"SJAG_03145":null,"SJAG_03379":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0002320"],"is_obsolete":false,"name":"typical nemaline myopathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1806265","UMLS:C5680453","GARD:12822","icd11.foundation:1105111633"],"synonyms":[{"name":"typical congenital nemaline myopathy","type":"related"}],"termid":"MONDO:0015737","terms_by_termid":{"MONDO:0008070":null,"MONDO:0009725":null,"MONDO:0012538":null},"xrefs":{"Monarch":{"xref_id":"0015737"}}}


id: PBO:0046117
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 4E binding protein 2 pseudogene 1","termid":"PBO:0046117"}


id: PBO:0036045
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_threonine_phosphorylation_at_Thr-Pro_site_during_vegetative_growth","termid":"PBO:0036045"}


id: MONDO:0005577
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete narcolepsy without cataplexy (obsolete MONDO:0005577)","termid":"MONDO:0005577","xrefs":{"Monarch":{"xref_id":"0005577"}}}


id: PBO:0001834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Myb family protein Eta2","termid":"PBO:0001834"}


id: PBO:0066425
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RERE antisense RNA 1","termid":"PBO:0066425"}


id: GO:0036305
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.","definition_xrefs":["CL:0000059"],"direct_ancestors":[{"relation_name":"is_a","term_name":"columnar/cuboidal epithelial cell differentiation","termid":"GO:0002065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ameloblast differentiation","termid":"GO:0036305"}


id: MONDO:0004383
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A central nervous system germinoma that occurs in an adult.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system germinoma","termid":"MONDO:0002999"},{"relation_name":"is_a","term_name":"adult central nervous system germ cell tumor","termid":"MONDO:0003405"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"adult central nervous system germinoma","secondary_identifiers":["MEDGEN:234581","DOID:7867","UMLS:C1370504","NCIT:C5792"],"synonyms":[{"name":"adult CNS germinoma","type":"exact"},{"name":"adult central nervous system germinoma","type":"exact"},{"name":"central nervous system germinoma","type":"broad"},{"name":"central nervous system germinoma of adults","type":"exact"},{"name":"germinoma of adult CNS","type":"exact"},{"name":"germinoma of adult central nervous system","type":"exact"},{"name":"germinoma of the adult CNS","type":"exact"},{"name":"germinoma of the adult central nervous system","type":"exact"}],"termid":"MONDO:0004383","xrefs":{"Monarch":{"xref_id":"0004383"}}}


id: GO:0004243
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete mitochondrial intermediate peptidase activity (obsolete GO:0004243)","synonyms":[{"name":"MIP","type":"broad"},{"name":"mitochondrial intermediate peptidase activity","type":"exact"},{"name":"mitochondrial intermediate precursor-processing proteinase activity","type":"related"}],"termid":"GO:0004243"}


id: GO:0002445
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid leukocyte mediated immunity","termid":"GO:0002444"},{"relation_name":"is_a","term_name":"hypersensitivity","termid":"GO:0002524"},{"relation_name":"is_a","term_name":"immunoglobulin mediated immune response","termid":"GO:0016064"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"type II hypersensitivity","secondary_identifiers":["Wikipedia:Type_II_hypersensitivity"],"termid":"GO:0002445"}


id: MONDO:0016913
data:
  {"annotated_genes":["SJAG_00441","SJAG_02846","SJAG_01804"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86510,86509,86508],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013256"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndrome caused by partial chromosomal deletion","termid":"MONDO:0000761"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00441":null,"SJAG_01804":null,"SJAG_02846":null},"genotype_count":0,"is_obsolete":false,"name":"partial deletion of the long arm of chromosome 15","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:444123","MESH:C538038","Orphanet:262119","UMLS:C2931708","GARD:20834"],"synonyms":[{"name":"15q deletion","type":"related"},{"name":"15q monosomy","type":"related"},{"name":"chromosome 15q deletion","type":"related"},{"name":"deletion 15q","type":"related"},{"name":"monosomy 15q","type":"related"},{"name":"partial deletion of chromosome 15q","type":"exact"},{"name":"partial deletion of the long arm of chromosome type 15","type":"exact"},{"name":"partial monosomy 15q","type":"related"},{"name":"partial monosomy of chromosome 15q","type":"exact"},{"name":"partial monosomy of the long arm of chromosome 15","type":"exact"}],"termid":"MONDO:0016913","terms_by_termid":{"MONDO:0013256":null},"xrefs":{"Monarch":{"xref_id":"0016913"}}}


id: PBO:0089921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GLYK family kinase of unknown specificity, implicated in nucleotide metabolism","termid":"PBO:0089921"}


id: MONDO:0006183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, benign process that affects the peritoneal cavity and is characterized by the formation of multiple small nodules that are composed of well differentiated smooth muscle. It usually affects adults in their late reproductive years. Most patients are asymptomatic. The tumor nodules may regress spontaneously.","definition_xrefs":["NCIT:C3958"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peritoneal benign neoplasm","termid":"MONDO:0000650"},{"relation_name":"is_a","term_name":"leiomyomatosis","termid":"MONDO:0003295"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"disseminated peritoneal leiomyomatosis","secondary_identifiers":["Orphanet:71274","DOID:5728","EFO:1000220","MEDGEN:78634","SCTID:62557001","UMLS:C0267785","GARD:12843"],"synonyms":[{"name":"DPL","type":"exact"},{"name":"LPD","type":"exact"},{"name":"diffuse peritoneal leiomyomatosis","type":"exact"},{"name":"disseminated peritoneal leiomyomatosis","type":"exact"},{"name":"leiomyomatosis peritonealis disseminata","type":"exact"},{"name":"leiomyomatosis peritonealis disseminate","type":"exact"}],"termid":"MONDO:0006183","xrefs":{"Monarch":{"xref_id":"0006183"}}}


id: MONDO:0044637
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"focal, segmental or multifocal dystonia","termid":"MONDO:0015990"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"infantile-onset generalized dyskinesia with orofacial involvement","secondary_identifiers":["Orphanet:494526","UMLS:C5567464","OMIM:616921","GARD:17905","MEDGEN:1798887"],"synonyms":[{"name":"IOLOD","type":"exact"},{"name":"dyskinesia, limb and orofacial, infantile-onset","type":"exact"},{"name":"infantile-onset orofacial-trunk-limbs dyskinesia","type":"exact"}],"termid":"MONDO:0044637","xrefs":{"Monarch":{"xref_id":"0044637"}}}


id: GO:0072086
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the loop of Henle of the kidney nephron acquires its identity.","definition_xrefs":["GOC:mtg_kidney_jan10","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"specification of nephron tubule identity","termid":"GO:0072081"},{"relation_name":"part_of","term_name":"loop of Henle development","termid":"GO:0072070"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"specification of loop of Henle identity","secondary_identifiers":["GO:0072083"],"synonyms":[{"name":"specification of intermediate tubule identity","type":"exact"}],"termid":"GO:0072086"}


id: MONDO:0006710
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and automatism may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)","definition_xrefs":["MESH:D017029"],"direct_ancestors":[{"relation_name":"is_a","term_name":"focal epilepsy","termid":"MONDO:0005384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"complex partial epilepsy","secondary_identifiers":["DOID:12382","SCTID:407675009","EFO:1000877","UMLS:C0085417","MEDGEN:43169","ICD9:345.40"],"synonyms":[{"name":"Complex partial epileptic seizure","type":"exact"},{"name":"epilepsy, psychomotor","type":"exact"},{"name":"psychomotor epilepsy","type":"exact"}],"termid":"MONDO:0006710","xrefs":{"Monarch":{"xref_id":"0006710"}}}


id: GO:1902994
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of phospholipid efflux.","definition_xrefs":["GO_REF:0000058","PMID:12042316","GOC:sjp","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of phospholipid transport","termid":"GO:2001138"},{"relation_name":"regulates","term_name":"phospholipid efflux","termid":"GO:0033700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of phospholipid efflux","synonyms":[{"name":"regulation of phospholipid export","type":"exact"}],"termid":"GO:1902994"}


id: PBO:0039446
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and IBR domain containing 1","termid":"PBO:0039446"}


id: GO:0071508
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete activation of MAPK activity involved in conjugation with cellular fusion (obsolete GO:0071508)","synonyms":[{"name":"activation of MAPK activity involved in mating response","type":"related"},{"name":"conjugation with cellular fusion, activation of MAPK activity","type":"exact"}],"termid":"GO:0071508"}


id: PBO:0109602
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 90 member A3","termid":"PBO:0109602"}


id: PBO:0084765
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial mRNA maturase with a role in splicing; encoded by both exon and intron sequences of partially processed COB mRNA","termid":"PBO:0084765"}


id: PBO:0028562
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-unequal_meiotic_sister_chromatid_segregation","termid":"PBO:0028562"}


id: GO:0004574
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.","definition_xrefs":["EC:3.2.1.10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-glucosidase activity","termid":"GO:0090599"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016798","GO:0003674","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"oligo-1,6-glucosidase activity","synonyms":[{"name":"alpha-limit dextrinase activity","type":"related"},{"name":"alpha-methylglucosidase activity","type":"related"},{"name":"dextrin 6-glucanohydrolase activity","type":"related"},{"name":"dextrin 6alpha-glucanohydrolase activity","type":"related"},{"name":"exo-oligo-1,6-glucosidase activity","type":"related"},{"name":"isomaltase activity","type":"related"},{"name":"limit dextrinase","type":"related"},{"name":"oligosaccharide alpha-1,6-glucohydrolase activity","type":"related"},{"name":"oligosaccharide alpha-1,6-glucosidase activity","type":"related"},{"name":"sucrase-isomaltase activity","type":"related"}],"termid":"GO:0004574"}


id: MONDO:0017761
data:
  {"annotated_genes":["SJAG_02117","SJAG_03371","SJAG_01007","SJAG_04260","SJAG_02399","SJAG_00379"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85862],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011417"},{"annotations":[85947],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0859328"},{"annotations":[85544],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012251"},{"annotations":[85805],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010651"},{"annotations":[85447],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008787"},{"annotations":[87443],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010572"},{"annotations":[85785],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044726"},{"annotations":[87484],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010200"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of metabolite absorption and transport","termid":"MONDO:0017757"}],"gene_count":6,"genes_by_uniquename":{"SJAG_00379":null,"SJAG_01007":null,"SJAG_02117":null,"SJAG_02399":null,"SJAG_03371":null,"SJAG_04260":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"disorder of mineral absorption and transport","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1842552","UMLS:C5681035","Orphanet:309836","GARD:21353","ICD10CM:E83.1","ICD10CM:E83.3","icd11.foundation:1833416892"],"termid":"MONDO:0017761","terms_by_termid":{"MONDO:0008787":null,"MONDO:0010200":null,"MONDO:0010572":null,"MONDO:0010651":null,"MONDO:0011417":null,"MONDO:0012251":null,"MONDO:0044726":null,"MONDO:0859328":null},"xrefs":{"Monarch":{"xref_id":"0017761"}}}


id: MONDO:0018275
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete salt and pepper syndrome (obsolete MONDO:0018275)","termid":"MONDO:0018275","xrefs":{"Monarch":{"xref_id":"0018275"}}}


id: PBO:0054245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1627","termid":"PBO:0054245"}


id: PBO:0089910
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Gmh5 alpha-1,2-galactosyltransferase","termid":"PBO:0089910"}


id: GO:0097133
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.","definition_xrefs":["PMID:15935619","GOC:so"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cyclin-dependent protein kinase holoenzyme complex","termid":"GO:0000307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"cyclin D3-CDK6 complex","termid":"GO:0097133"}


id: GO:0031230
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.","definition_xrefs":["GOC:dos","GOC:mtg_sensu","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete intrinsic component of cell outer membrane (obsolete GO:0031230)","synonyms":[{"name":"intrinsic to cell outer membrane","type":"narrow"}],"termid":"GO:0031230"}


id: GO:0061316
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Wnt signaling pathway involved in heart development","termid":"GO:0003306"},{"relation_name":"is_a","term_name":"canonical Wnt signaling pathway","termid":"GO:0060070"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"canonical Wnt signaling pathway involved in heart development","synonyms":[{"name":"canonical Wnt receptor signaling pathway involved in heart development","type":"exact"},{"name":"canonical Wnt receptor signalling pathway involved in heart development","type":"exact"},{"name":"canonical Wnt-activated signaling pathway involved in heart development","type":"exact"}],"termid":"GO:0061316"}


id: PBO:0084332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kinesin-like myosin passenger-protein; interacts with Myo2p and enhances its interaction with Sec4p during transport of secretory vesicles; controls actin cable structure and dynamics","termid":"PBO:0084332"}


id: PBO:0082254
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha subunit of Type II geranylgeranyltransferase; required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p","termid":"PBO:0082254"}


id: GO:0008992
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the hydrolysis of Ala-Gly bond in repressor lexA.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete repressor LexA activity (obsolete GO:0008992)","synonyms":[{"name":"LexA repressor","type":"related"},{"name":"repressor LexA activity","type":"exact"},{"name":"repressor lexA","type":"related"}],"termid":"GO:0008992"}


id: PBO:0048442
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanylate binding protein 5","termid":"PBO:0048442"}


id: MONDO:0015760
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-Hodgkin lymphoma of T-cell lineage. It includes the T lymphoblastic lymphoma and the mature T- and NK-cell lymphomas. -- 2003","definition_xrefs":["NCIT:C3466"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-Hodgkin lymphoma","termid":"MONDO:0018908"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"T-cell non-Hodgkin lymphoma","secondary_identifiers":["SCTID:109978004","DOID:0081312","GARD:20133","Orphanet:171918","UMLS:C0079772","MESH:D016399","ICD9:202.70","MedDRA:10042971","MEDGEN:86957"],"synonyms":[{"name":"T cell lymphoma","type":"exact"},{"name":"T-cell NHL","type":"exact"},{"name":"T-cell and NK-cell non-Hodgkin lymphoma","type":"exact"},{"name":"T-cell and NK-cell non-Hodgkin's lymphoma","type":"exact"},{"name":"T-cell lymphoma","type":"exact"},{"name":"T-cell non-Hodgkin lymphoma","type":"exact"},{"name":"T-cell non-Hodgkin's lymphoma","type":"exact"},{"name":"non-Hodgkin's T-cell lymphoma","type":"exact"}],"termid":"MONDO:0015760","xrefs":{"Monarch":{"xref_id":"0015760"}}}


id: MOD:01697
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces a residue alpha-amino- or alpha-imino-hydrogen with an 4-(2-aminoethyl)benzenesulfonyl group.","definition_xrefs":["PubMed:8597590","DeltaMass:235","Unimod:276#N-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"4-(2-aminoethyl)benzenesulfonyl fluoride derivatized residue","termid":"MOD:00596"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-amino 4-(2-aminoethyl)benzenesulfonylated residue","synonyms":[{"name":"AEBS","type":"related"},{"name":"Aminoethylbenzenesulfonylation","type":"related"}],"termid":"MOD:01697"}


id: GO:0009538
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin.","definition_xrefs":["GOC:kd","ISBN:0943088399"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"part_of","term_name":"photosystem I","termid":"GO:0009522"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"photosystem I reaction center","synonyms":[{"name":"photosystem I reaction centre","type":"exact"}],"termid":"GO:0009538"}


id: GO:0060675
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the ureteric bud is generated and organized.","definition_xrefs":["GOC:dph","GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesonephric tubule morphogenesis","termid":"GO:0072171"},{"relation_name":"part_of","term_name":"ureteric bud development","termid":"GO:0001657"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ureteric bud morphogenesis","termid":"GO:0060675"}


id: MONDO:0100342
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A grade III or grade IV glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma.","definition_xrefs":["NCIT:C4822"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system cancer","termid":"MONDO:0002714"},{"relation_name":"is_a","term_name":"high grade malignant neoplasm","termid":"MONDO:0020665"},{"relation_name":"is_a","term_name":"glioma","termid":"MONDO:0021042"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"malignant glioma","secondary_identifiers":["UMLS:C0555198","MEDGEN:107826","MedDRA:10018338","DOID:3070","ICDO:9380/3"],"synonyms":[{"name":"glial cell tumor","type":"exact"},{"name":"glial cell tumour","type":"exact"},{"name":"glioma","type":"broad"},{"name":"glioma, malignant","type":"exact"},{"name":"high grade glioma","type":"exact"},{"name":"high-grade glioma","type":"exact"},{"name":"malignant glial neoplasm","type":"exact"},{"name":"malignant glial tumor","type":"exact"},{"name":"malignant glial tumour","type":"exact"},{"name":"malignant glioma","type":"exact"},{"name":"malignant neuroglial neoplasm","type":"exact"},{"name":"malignant neuroglial tumor","type":"exact"},{"name":"malignant neuroglial tumour","type":"exact"},{"name":"neuroglial tumor","type":"broad"},{"name":"neuroglial tumour","type":"broad"}],"termid":"MONDO:0100342","xrefs":{"Monarch":{"xref_id":"0100342"}}}


id: PBO:0001563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"recombination protein Irc6 (predicted)","termid":"PBO:0001563"}


id: GO:0098036
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends.","definition_xrefs":["GOC:bm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral DNA genome packaging via site-specific sequence recognition","termid":"GO:0098035"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"viral DNA genome packaging, 3' extended cos packaging","termid":"GO:0098036"}


id: PBO:0089510
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DUF5102 family conserved fungal protein, associated with clathrin coated vesicles","termid":"PBO:0089510"}


id: PBO:0047160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 186 member B","termid":"PBO:0047160"}


id: MONDO:0019609
data:
  {"annotated_genes":["SJAG_03781","SJAG_00326","SJAG_02693","SJAG_02619","SJAG_05950","SJAG_00891","SJAG_01165","SJAG_04146","SJAG_02788","SJAG_00702","SJAG_03324","SJAG_02997","SJAG_04763","SJAG_03440"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87587],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013948"},{"annotations":[87231],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054549"},{"annotations":[87588],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013949"},{"annotations":[87586],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013950"},{"annotations":[87589],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013951"},{"annotations":[87590],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013952"},{"annotations":[87548,87547],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013967"},{"annotations":[87194],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008953"},{"annotations":[87538],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011101"},{"annotations":[87183],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008954"},{"annotations":[87452],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008736"},{"annotations":[87570],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013927"},{"annotations":[87572],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013930"},{"annotations":[87573],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013931"},{"annotations":[87575],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013936"},{"annotations":[87577],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013937"},{"annotations":[87578],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013938"},{"annotations":[87576],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013939"},{"annotations":[87581],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013942"},{"annotations":[87579],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013943"},{"annotations":[87584],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013945"},{"annotations":[86655],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009959"}]},"cv_name":"mondo","definition":"The most severe variant seen in the peroxisome biogenesis disorders that is characterized by neuronal migration defects in the brain, dysmorphic craniofacial features, profound hypotonia, neonatal seizures, and liver dysfunction.","definition_xrefs":["Orphanet:912"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"excluded_subClassOf","term_name":"obsolete nephropathy secondary to a storage or other metabolic disease (obsolete MONDO:0019743)","termid":"MONDO:0019743"},{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"peroxisome biogenesis 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disorders","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD10CM:E71.510","GARD:7917","MEDGEN:21958","NORD:1876","UMLS:C0043459","SCTID:88469006","NCIT:C85239","DOID:905","MESH:D015211","NANDO:1200760"],"synonyms":[{"name":"ZS","type":"exact"},{"name":"ZWS","type":"exact"},{"name":"Zellweger leukodystrophy","type":"related"},{"name":"Zellweger spectrum disorders","type":"exact"},{"name":"Zellweger syndrome","type":"exact"},{"name":"cerebrohepatorenal syndrome","type":"exact"},{"name":"congenital iron overload","type":"exact"}],"termid":"MONDO:0019609","terms_by_termid":{"MONDO:0008736":null,"MONDO:0008953":null,"MONDO:0008954":null,"MONDO:0009959":null,"MONDO:0011101":null,"MONDO:0013927":null,"MONDO:0013930":null,"MONDO:0013931":null,"MONDO:0013936":null,"MONDO:0013937":null,"MONDO:0013938":null,"MONDO:0013939":null,"MONDO:0013942":null,"MONDO:0013943":null,"MONDO:0013945":null,"MONDO:0013948":null,"MONDO:0013949":null,"MONDO:0013950":null,"MONDO:0013951":null,"MONDO:0013952":null,"MONDO:0013967":null,"MONDO:0054549":null},"xrefs":{"Monarch":{"xref_id":"0019609"}}}


id: MONDO:1012478
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"upper airway syndrome, non-human animal","termid":"MONDO:1011931"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"upper airway syndrome, dog","secondary_identifiers":["OMIA:001893-9615"],"termid":"MONDO:1012478","xrefs":{"Monarch":{"xref_id":"1012478"}}}


id: GO:0048022
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of melanin biosynthetic process","termid":"GO:0048021"},{"relation_name":"is_a","term_name":"negative regulation of secondary metabolite biosynthetic process","termid":"GO:1900377"},{"relation_name":"negatively_regulates","term_name":"melanin biosynthetic process","termid":"GO:0042438"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"negative regulation of melanin biosynthetic process","synonyms":[{"name":"down regulation of melanin biosynthetic process","type":"exact"},{"name":"down-regulation of melanin biosynthetic process","type":"exact"},{"name":"downregulation of melanin biosynthetic process","type":"exact"},{"name":"inhibition of melanin biosynthetic process","type":"narrow"},{"name":"negative regulation of melanin anabolism","type":"exact"},{"name":"negative regulation of melanin biosynthesis","type":"exact"},{"name":"negative regulation of melanin formation","type":"exact"},{"name":"negative regulation of melanin synthesis","type":"exact"}],"termid":"GO:0048022"}


id: GO:0032567
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to dGTP, deoxyguanosine triphosphate.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"guanyl deoxyribonucleotide binding","termid":"GO:0032560"},{"relation_name":"is_a","term_name":"anion binding","termid":"GO:0043168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"dGTP binding","termid":"GO:0032567"}


id: GO:0085018
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment.","definition_xrefs":["GOC:jl","PMID:18665841","GOC:yaf"],"gene_count":0,"genotype_count":0,"name":"obsolete maintenance of symbiont-containing vacuole by host (obsolete GO:0085018)","synonyms":[{"name":"maintenance of parasitophorous vacuole","type":"exact"},{"name":"maintenance of pathogen-containing vacuole","type":"exact"},{"name":"maintenance of vacuolar integrity during bacterial infection","type":"narrow"}],"termid":"GO:0085018"}


id: MONDO:0009801
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial osteodysplasia, Anderson type is a rare, genetic dysostosis disorder characterized by craniofacial bone abnormalities (i.e. midface hypoplasia, broad, flat nasal bridge, narrow, thin prognathic mandible with pointed chin, malocclusion, partial dental agenesis) associated with additional osseous anomalies, including scoliosis, calvarial thinning, pointed spinous processes, clinodactyly and abnormal phalanges. Elevated erythrocyte sedimentation rate, hyperuricemia and hypertension have also been reported. There have been no further descriptions in the literature since 1982.","definition_xrefs":["Orphanet:2769"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"familial osteodysplasia, Anderson type","secondary_identifiers":["MESH:C564923","UMLS:C1850186","OMIM:259250","MEDGEN:337990","GARD:4136","icd11.foundation:107132680"],"synonyms":[{"name":"osteodysplasia familial Anderson type","type":"related"},{"name":"osteodysplasia, familial, Anderson type","type":"related"}],"termid":"MONDO:0009801","xrefs":{"Monarch":{"xref_id":"0009801"}}}


id: GO:0018185
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.","definition_xrefs":["RESID:AA0278"],"gene_count":0,"genotype_count":0,"name":"obsolete poly-N-methyl-propylamination (obsolete GO:0018185)","termid":"GO:0018185"}


id: GO:0010629
data:
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id: FYPO:0001986
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-fluorouracil than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002682"}],"interesting_parent_ids":["FYPO:0002682","FYPO:0000003","FYPO:0005447","FYPO:0000139","FYPO:0001985"],"is_obsolete":false,"name":"resistance to 5-fluorouracil","synonyms":[{"name":"resistance to 5-FU","type":"exact"},{"name":"resistance to 5-fluorouracil during mitotic cell cycle","type":"related"},{"name":"resistance to 5-fluorouracil during vegetative growth","type":"exact"},{"name":"resistant to 5-fluorouracil","type":"exact"}],"termid":"FYPO:0001986"}


id: GO:0003850
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.","definition_xrefs":["EC:3.1.3.68"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sugar-phosphatase activity","termid":"GO:0050308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016788","GO:0016787"],"is_obsolete":false,"name":"2-deoxyglucose-6-phosphatase activity","secondary_identifiers":["KEGG_REACTION:R02587","MetaCyc:3.1.3.68-RXN","RHEA:22236"],"synonyms":[{"name":"2-deoxy-D-glucose-6-phosphate phosphohydrolase activity","type":"related"},{"name":"2-deoxyglucose-6-phosphate phosphatase activity","type":"related"}],"termid":"GO:0003850"}


id: PR:O94319
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein SEC13 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11024:SF2","OMA:SCHPO03972","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein transport protein sec13 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC215.15","secondary_identifiers":["UniProtKB:O94319"],"synonyms":[{"name":"Spom972h-SEC13","type":"exact"}],"termid":"PR:O94319"}


id: _global:results_in_developmental_progression_of
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss).","direct_ancestors":[{"relation_name":"is_a","term_name":"developmentally_related_to","termid":"RO:0002324"},{"relation_name":"is_a","term_name":"developmentally_related_to","termid":"_global:developmentally_related_to"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"results_in_developmental_progression_of","secondary_identifiers":["RO:0002295"],"termid":"_global:results_in_developmental_progression_of"}


id: PBO:0001299
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial TOM complex subunit Tom22 (predicted)","termid":"PBO:0001299"}


id: GO:0004311
data:
  {"annotated_genes":["SJAG_03352","SJAG_00580"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[99922,109792],"is_not":false,"summary":null,"term":"GO:0004311"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate.","definition_xrefs":["RHEA:17653"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prenyl diphosphate synthase activity","termid":"GO:0120531"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00580":null,"SJAG_03352":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016765"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0016765","GO:0003674"],"is_obsolete":false,"name":"geranylgeranyl diphosphate synthase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["EC:2.5.1.29","KEGG_REACTION:R02061","MetaCyc:FARNESYLTRANSTRANSFERASE-RXN"],"synonyms":[{"name":"farnesyltranstransferase activity","type":"exact"},{"name":"geranylgeranyl pyrophosphate synthase activity","type":"exact"},{"name":"geranylgeranyl pyrophosphate synthetase activity","type":"exact"},{"name":"geranylgeranyl-PP synthetase activity","type":"exact"},{"name":"geranylgeranyl-diphosphate synthase activity","type":"exact"},{"name":"trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity","type":"related"}],"termid":"GO:0004311","terms_by_termid":{"GO:0004311":null}}


id: MONDO:0011584
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations is a rare cancer-predisposing syndrome, associated with the D1 subgroup of Fanconi anemia (FA), characterized by progressive bone marrow failure, cardiac, brain, intestinal or skeletal abnormalities and predisposition to various malignancies. Bone marrow suppression and the incidence of developmental abnormalities are less frequent than in other FA, but cancer risk is very high with the spectrum of childhood cancers including Wilms tumor, brain tumor (often medulloblastoma) and ALL/AML.","definition_xrefs":["Orphanet:319462"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Fanconi anemia","termid":"MONDO:0019391"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0021190"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0021190","MONDO:0002280","MONDO:0005570","MONDO:0005066"],"is_obsolete":false,"name":"Fanconi anemia complementation group D1","secondary_identifiers":["GARD:17449","MESH:C563980","NCIT:C125705","SCTID:766707003","OMIM:605724","DOID:0111089","MEDGEN:325420","UMLS:C1838457"],"synonyms":[{"name":"FAD1","type":"exact"},{"name":"FANCD1","type":"exact"},{"name":"Fad1","type":"related"},{"name":"Fanconi anemia complementation group D1","type":"exact"},{"name":"Fanconi anemia, complementation group D1","type":"related"},{"name":"inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations","type":"related"}],"termid":"MONDO:0011584","xrefs":{"Monarch":{"xref_id":"0011584"}}}


id: PBO:0076588
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TBC1 domain family member 10A","termid":"PBO:0076588"}


id: PBO:0042329
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD52 molecule","termid":"PBO:0042329"}


id: PBO:0062771
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 52 subfamily Y member 1 pseudogene","termid":"PBO:0062771"}


id: PBO:0082971
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic protein that regulates protein phosphatase 1 Glc7p; protein overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate","termid":"PBO:0082971"}


id: PBO:0055867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich pentatricopeptide repeat containing","termid":"PBO:0055867"}


id: PBO:0064103
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"piwi like RNA-mediated gene silencing 4","termid":"PBO:0064103"}


id: PBO:0003337
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.1.3.36","termid":"PBO:0003337"}


id: GO:0022019
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.","definition_xrefs":["GOC:dph","GOC:cls","GOC:dgh","GOC:jid","GO_REF:0000021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"subpallium cell proliferation in forebrain","termid":"GO:0022012"},{"relation_name":"part_of","term_name":"lateral ganglionic eminence cell proliferation","termid":"GO:0022018"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dorsal lateral ganglionic eminence cell proliferation","termid":"GO:0022019"}


id: GO:0106377
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-hydroxy-ATP + H2O = 2-hydroxy-AMP + H+ + diphosphate.","definition_xrefs":["RHEA:67392","PMID:11139615"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside triphosphate diphosphatase activity","termid":"GO:0047429"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0047429"}],"interesting_parent_ids":["GO:0047429","GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"2-hydroxy-ATP hydrolase activity","secondary_identifiers":["Reactome:R-HSA-2395872"],"termid":"GO:0106377"}


id: SO:0000850
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A component of the five-prime long terminal repeat.","definition_xrefs":["PMID:8649407"],"direct_ancestors":[{"relation_name":"is_a","term_name":"LTR_component","termid":"SO:0000848"},{"relation_name":"part_of","term_name":"five_prime_LTR","termid":"SO:0000425"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"five_prime_LTR_component","synonyms":[{"name":"5' long term repeat component","type":"exact"},{"name":"five prime LTR component","type":"exact"}],"termid":"SO:0000850"}


id: MOD:00346
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-cysteine residue and an L-phenylalanine residue by a thioether bond to form 2-(S-L-cysteinyl)-D-phenylalanine.","definition_xrefs":["RESID:AA0341","PubMed:12696888","PubMed:3936839"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stereoisomerized residue","termid":"MOD:00664"},{"relation_name":"is_a","term_name":"alpha-carbon thioether crosslinked residues","termid":"MOD:01992"},{"relation_name":"is_a","term_name":"crosslinked L-phenylalanine residue","termid":"MOD:02053"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"2-(S-L-cysteinyl)-D-phenylalanine","synonyms":[{"name":"(2S)-2-amino-2-[(2R)-2-amino-2-carboxyethyl]sulfanyl-3-phenylpropanoic acid","type":"exact"},{"name":"(2S,5R)-2,5-diamino-3-thia-2-phenylmethylhexanedioic acid","type":"exact"},{"name":"2-(L-cystein-S-yl)-D-phenylalanine","type":"exact"},{"name":"CROSSLNK 2-cysteinyl-D-phenylalanine (Cys-Phe)","type":"exact"},{"name":"alpha-(L-cystein-S-yl)-D-phenylalanine","type":"exact"}],"termid":"MOD:00346"}


id: GO:0009923
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A tetrameric complex of four different subunits which catalyzes the elongation of a fatty acid chain 2 carbon units at a time in the synthesis of very long chain fatty acids.","definition_xrefs":["GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"is_a","term_name":"endoplasmic reticulum protein-containing complex","termid":"GO:0140534"},{"relation_name":"is_a","term_name":"transferase complex","termid":"GO:1990234"},{"relation_name":"part_of","term_name":"endoplasmic reticulum membrane","termid":"GO:0005789"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005789"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005783"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005783","GO:0005737","GO:0005789"],"is_obsolete":false,"name":"fatty acid elongase complex","termid":"GO:0009923"}


id: MONDO:0018113
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Isolated synostotic plagiocephaly (SP) is a form of nonsyndromic craniosynostosis characterized by premature fusion of one coronal suture leading to skull deformity and facial asymmetry.","definition_xrefs":["Orphanet:35098"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete neuro-ophthalmological disease (obsolete MONDO:0015368)","termid":"MONDO:0015368"}],"gene_count":0,"genotype_count":0,"name":"obsolete isolated plagiocephaly (obsolete MONDO:0018113)","synonyms":[{"name":"non-syndromic unicoronal synostosis","type":"exact"},{"name":"synostotic plagiocephaly","type":"exact"}],"termid":"MONDO:0018113","xrefs":{"Monarch":{"xref_id":"0018113"}}}


id: _global:directly_regulated_by
data:
  {"annotation_feature_type":"gene","cv_name":"external","direct_ancestors":[{"relation_name":"is_a","term_name":"regulated_by","termid":"_global:regulated_by"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"directly_regulated_by","secondary_identifiers":["RO:0002022"],"termid":"_global:directly_regulated_by"}


id: GO:0001027
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.","definition_xrefs":["PMID:12381659","GOC:txnOH-2018"],"gene_count":0,"genotype_count":0,"name":"obsolete RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity (obsolete GO:0001027)","synonyms":[{"name":"RNA polymerase III type 1 promoter polymerase recruiting transcription factor activity","type":"related"}],"termid":"GO:0001027"}


id: PR:Q9Y8G3
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A nuclear RNA export factor 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA export factor mex67 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC1921.03c","secondary_identifiers":["UniProtKB:Q9Y8G3"],"synonyms":[{"name":"SPBC1921.03c","type":"related"},{"name":"Spom972h-NXF1","type":"exact"}],"termid":"PR:Q9Y8G3"}


id: GO:2000007
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.","definition_xrefs":["GOC:yaf","GOC:obol","GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"regulation of metanephric comma-shaped body morphogenesis","termid":"GO:2000006"},{"relation_name":"negatively_regulates","term_name":"metanephric comma-shaped body morphogenesis","termid":"GO:0072278"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of metanephric comma-shaped body morphogenesis","termid":"GO:2000007"}


id: GO:1905254
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any positive regulation of epidermal growth factor receptor signaling pathway that is involved in heart process.","definition_xrefs":["GOC:BHF","GOC:TermGenie","GO_REF:0000060","GOC:BHF_miRNA","PMID:23069713","GOC:bc"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of epidermal growth factor receptor signaling pathway involved in heart process (obsolete GO:1905254)","synonyms":[{"name":"activation of epidermal growth factor receptor signaling pathway involved in cardiac process","type":"related"},{"name":"activation of epidermal growth factor receptor signaling pathway involved in heart process","type":"narrow"},{"name":"positive regulation of EGF receptor signaling pathway involved in cardiac process","type":"related"},{"name":"positive regulation of EGF receptor signaling pathway involved in heart process","type":"exact"},{"name":"positive regulation of EGF receptor signalling pathway involved in cardiac process","type":"related"},{"name":"positive regulation of EGF receptor signalling pathway involved in heart process","type":"exact"},{"name":"positive regulation of EGFR signaling pathway involved in cardiac process","type":"related"},{"name":"positive regulation of EGFR signaling pathway involved in heart process","type":"exact"},{"name":"positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process","type":"related"},{"name":"stimulation of epidermal growth factor receptor signaling pathway involved in cardiac process","type":"related"},{"name":"stimulation of epidermal growth factor receptor signaling pathway involved in heart process","type":"narrow"},{"name":"up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process","type":"related"},{"name":"up regulation of epidermal growth factor receptor signaling pathway involved in heart process","type":"exact"},{"name":"up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process","type":"related"},{"name":"up-regulation of epidermal growth factor receptor signaling pathway involved in heart process","type":"exact"},{"name":"upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process","type":"related"},{"name":"upregulation of epidermal growth factor receptor signaling pathway involved in heart process","type":"exact"}],"termid":"GO:1905254"}


id: GO:0035195
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants.","definition_xrefs":["PMID:15066283","PMID:23209154","GOC:rl","PMID:23985560","GOC:bc","GOC:aruk","PMID:14744438","PMID:15066275","PMID:28379604"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulatory ncRNA-mediated post-transcriptional gene silencing","termid":"GO:0035194"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"miRNA-mediated post-transcriptional gene silencing","secondary_identifiers":["Reactome:R-HSA-9759811"],"synonyms":[{"name":"gene silencing by miRNA","type":"exact"},{"name":"gene silencing by microRNA","type":"exact"},{"name":"miRNA-mediated gene silencing","type":"broad"},{"name":"microRNA-mediated gene silencing","type":"exact"}],"termid":"GO:0035195"}


id: PBO:0078169
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor beta diversity 2","termid":"PBO:0078169"}


id: GO:0008298
data:
  {"annotated_genes":["SJAG_03696"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117586],"is_not":false,"summary":null,"term":"GO:0008298"}]},"cv_name":"biological_process","definition":"Any process in which mRNA is transported to, or maintained in, a specific location within the cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA localization","termid":"GO:0006403"},{"relation_name":"is_a","term_name":"cellular macromolecule localization","termid":"GO:0070727"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03696":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"intracellular mRNA localization","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"establishment and maintenance of intracellular RNA localization","type":"exact"},{"name":"intracellular mRNA localisation","type":"exact"},{"name":"intracellular mRNA positioning","type":"narrow"},{"name":"mRNA localization, intracellular","type":"exact"},{"name":"mRNA positioning, intracellular","type":"narrow"}],"termid":"GO:0008298","terms_by_termid":{"GO:0008298":null}}


id: PBO:0090361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-protein ligase E3, unknown specificity","termid":"PBO:0090361"}


id: PBO:0075441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"secreted protein acidic and cysteine rich","termid":"PBO:0075441"}


id: PBO:0076366
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trace amine associated receptor 3, pseudogene","termid":"PBO:0076366"}


id: MONDO:0002831
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A squamous cell carcinoma of the sinonasal tract characterized by a plexiform or ribbon-like growth pattern, cytological atypia, and lack of histological evidence of keratinization.","definition_xrefs":["NCIT:C54287"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"maxillary sinus carcinoma","termid":"MONDO:0001748"},{"relation_name":"is_a","term_name":"nasal cavity and paranasal sinus squamous cell carcinoma","termid":"MONDO:0044787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"non-keratinizing sinonasal squamous cell carcinoma","secondary_identifiers":["DOID:4003","ICDO:8121/3","MEDGEN:83119","ONCOTREE:SNSC","UMLS:C0334270"],"synonyms":[{"name":"Ringertz carcinoma","type":"related"},{"name":"Schneiderian carcinoma","type":"related"},{"name":"Sinonasal Schneiderian carcinoma","type":"related"},{"name":"Sinonasal cylindrical cell carcinoma","type":"related"},{"name":"Sinonasal transitional cell carcinoma","type":"related"},{"name":"cylindrical cell carcinoma","type":"exact"},{"name":"non-keratinizing sinonasal squamous cell carcinoma","type":"exact"},{"name":"sinonasal squamous cell carcinoma","type":"related"}],"termid":"MONDO:0002831","xrefs":{"Monarch":{"xref_id":"0002831"}}}


id: GO:0044216
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A cell of a secondary organism with which the first organism is interacting.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete other organism cell (obsolete GO:0044216)","termid":"GO:0044216"}


id: PBO:0001488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial respiratory complex assembly protein (predicted)","termid":"PBO:0001488"}


id: MONDO:0020468
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Paternal uniparental disomy of chromosome 13 is an uniparental disomy of paternal origin that most likely does not have any phenotypic expression except from cases of homozygosity for a recessive disease mutation for which only father is a carrier.","definition_xrefs":["Orphanet:99324"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome 13 disorder","termid":"MONDO:0700020"},{"relation_name":"is_a","term_name":"uniparental disomy","termid":"MONDO:0700086"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paternal uniparental disomy of chromosome 13","secondary_identifiers":["GARD:19678","MEDGEN:1653904","icd11.foundation:2090405609","UMLS:C4722326"],"synonyms":[{"name":"UPD(13)pat","type":"exact"},{"name":"paternal uniparental disomy of chromosome type 13","type":"exact"}],"termid":"MONDO:0020468","xrefs":{"Monarch":{"xref_id":"0020468"}}}


id: PR:Q9UST2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A mitochondrial inner membrane protease subunit 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03408","PRO:DNx","PANTHER:PTHR12383:SF3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial inner membrane protease subunit 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC336.13c","secondary_identifiers":["UniProtKB:Q9UST2"],"synonyms":[{"name":"Spom972h-IMMP2L","type":"exact"}],"termid":"PR:Q9UST2"}


id: MONDO:0003148
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete SM-AHNMD (obsolete MONDO:0003148)","termid":"MONDO:0003148","xrefs":{"Monarch":{"xref_id":"0003148"}}}


id: PR:Q9C111
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC343.20 gene.","definition_xrefs":["UniProtKB:Q9C111","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C343.20 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC343.20","synonyms":[{"name":"Spom972h-SPAC343.20","type":"exact"}],"termid":"PR:Q9C111"}


id: PBO:0056736
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MET proto-oncogene, receptor tyrosine kinase","termid":"PBO:0056736"}


id: FYPO:0000511
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nuclear fusion during mating","termid":"FYPO:0000510"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000301"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000301","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abolished nuclear fusion during mating","synonyms":[{"name":"abolished nuclear fusion during conjugation","type":"exact"},{"name":"absent nuclear fusion during mating","type":"exact"},{"name":"karyogamy abolished","type":"exact"},{"name":"karyogamy involved in conjugation with cellular fusion abolished","type":"exact"},{"name":"nuclear fusion during mating abolished","type":"exact"},{"name":"nuclear fusion during mating: absent","type":"related"}],"termid":"FYPO:0000511"}


id: GO:0034413
data:
  {"annotated_genes":["SJAG_03587","SJAG_04666","SJAG_04771"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94802],"is_not":false,"summary":null,"term":"GO:0034413"},{"annotations":[87860,92762],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:0140748"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ascospore wall (1->3)-beta-D-glucan metabolic process","termid":"GO:0034409"},{"relation_name":"is_a","term_name":"ascospore wall beta-glucan biosynthetic process","termid":"GO:0034412"},{"relation_name":"is_a","term_name":"fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process","termid":"GO:0071970"}],"gene_count":3,"genes_by_uniquename":{"SJAG_03587":null,"SJAG_04666":null,"SJAG_04771":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0030437"},{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"part_of","termid":"GO:0071554"}],"interesting_parent_ids":["GO:0044085","GO:0007049","GO:0005975","GO:0071554","GO:0008150","GO:0030437"],"is_obsolete":false,"name":"ascospore wall (1->3)-beta-D-glucan biosynthetic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"ascospore wall 1,3-beta-D-glucan biosynthetic process","type":"broad"},{"name":"ascospore wall 1,3-beta-glucan anabolism","type":"exact"},{"name":"ascospore wall 1,3-beta-glucan biosynthesis","type":"exact"},{"name":"ascospore wall 1,3-beta-glucan biosynthetic process","type":"broad"},{"name":"ascospore wall 1,3-beta-glucan formation","type":"exact"},{"name":"ascospore wall 1,3-beta-glucan synthesis","type":"exact"},{"name":"ascospore wall beta-1,3-glucan anabolism","type":"exact"},{"name":"ascospore wall beta-1,3-glucan biosynthesis","type":"exact"},{"name":"ascospore wall beta-1,3-glucan biosynthetic process","type":"exact"},{"name":"ascospore wall beta-1,3-glucan formation","type":"exact"},{"name":"ascospore wall beta-1,3-glucan synthesis","type":"exact"}],"termid":"GO:0034413","terms_by_termid":{"GO:0034413":null,"GO:0140748":null}}


id: FYPO:0002851
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the eisosome is observed there.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mislocalized protein during vegetative growth","termid":"FYPO:0000782"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"protein mislocalized to eisosome","synonyms":[{"name":"ectopic protein localization to eisosome","type":"exact"},{"name":"protein mislocalised to eisosome","type":"exact"},{"name":"protein mislocalised to eisosome during vegetative growth","type":"exact"},{"name":"protein mislocalized to eisosome during mitotic cell cycle","type":"related"},{"name":"protein mislocalized to eisosome during vegetative growth","type":"exact"}],"termid":"FYPO:0002851"}


id: PR:Q9UTK0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An RNA-binding protein NOB1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR12814:SF0","PRO:DNx","OMA:SCHPO01341"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S-pre-rRNA D-site endonuclease nob1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1486.09","secondary_identifiers":["UniProtKB:Q9UTK0"],"synonyms":[{"name":"Spom972h-NOB1","type":"exact"},{"name":"pre-rRNA-processing endonuclease nob1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UTK0"}


id: PBO:0051184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 3-75 (pseudogene)","termid":"PBO:0051184"}


id: PBO:0017033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces pombe specific protein, predicted GPI anchored","termid":"PBO:0017033"}


id: GO:0014065
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.","definition_xrefs":["Wikipedia:PI3K","GOC:ef","PMID:22525052"],"gene_count":0,"genotype_count":0,"name":"obsolete phosphatidylinositol 3-kinase signaling (obsolete GO:0014065)","synonyms":[{"name":"PI 3-kinase cascade","type":"exact"},{"name":"PI3K cascade","type":"exact"},{"name":"PI3K signal transduction","type":"exact"},{"name":"PI3K signaling","type":"exact"},{"name":"phosphatidylinositol 3-kinase cascade","type":"related"},{"name":"phosphatidylinositol 3-kinase signal transduction","type":"exact"},{"name":"phosphoinositide 3-kinase cascade","type":"exact"}],"termid":"GO:0014065"}


id: PBO:0078016
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 6","termid":"PBO:0078016"}


id: PBO:0067502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 640, pseudogene","termid":"PBO:0067502"}


id: PBO:0090805
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane anchored protein, claudin family, SUR7 subfamily, predicted membrane sensor Pun1","termid":"PBO:0090805"}


id: PBO:0056717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mesenchyme homeobox 2","termid":"PBO:0056717"}


id: PBO:0081938
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger HIT-type containing 1 pseudogene 1","termid":"PBO:0081938"}


id: PBO:0040414
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase H+ transporting V0 subunit b","termid":"PBO:0040414"}


id: PBO:0028777
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_caffeine_and_rapamycin","termid":"PBO:0028777"}


id: MONDO:1011445
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fibrocartilaginous embolic myelopathy that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cardiovascular disorder, non-human animal","termid":"MONDO:1011306"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fibrocartilaginous embolic myelopathy, non-human animal","secondary_identifiers":["OMIA:001120"],"termid":"MONDO:1011445","xrefs":{"Monarch":{"xref_id":"1011445"}}}


id: GO:0030699
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: acetyl phosphate + H2O + NH4 + thioredoxin disulfide = glycine + H+ + phosphate + thioredoxin.","definition_xrefs":["EC:1.21.4.2","RHEA:12232"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor","termid":"GO:0050485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"glycine reductase activity","secondary_identifiers":["KEGG_REACTION:R07226","MetaCyc:RXN-7566"],"synonyms":[{"name":"acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming)","type":"related"}],"termid":"GO:0030699"}


id: MOD:00758
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-proline residue to O4-(N-acetylamino)glucosyl-L-hydroxyproline.","definition_xrefs":["PubMed:9660787","RESID:AA0390","PubMed:15238247"],"direct_ancestors":[{"relation_name":"is_a","term_name":"N-acetylaminoglucosylated residue","termid":"MOD:00448"},{"relation_name":"is_a","term_name":"O4-(N-acetylamino)hexosyl-L-hydroxyproline","termid":"MOD:01677"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"O4-(N-acetylamino)glucosyl-L-hydroxyproline","synonyms":[{"name":"(2S,4R)-4-[2-acetamido-2-deoxy-alpha-D-glucopyranosyloxy]pyrrolidine-2-carboxylic acid","type":"exact"},{"name":"4-(N-acetylglucosaminyloxy)proline","type":"exact"},{"name":"4-[(2-N-acetylamino)-alpha-D-glucopyranosyl]oxyproline","type":"exact"},{"name":"CARBOHYD O-linked (GlcNAc) hydroxyproline","type":"exact"},{"name":"HexNAc","type":"related"},{"name":"O4-(N-acetylamino)glucosyl-L-hydroxyproline","type":"exact"},{"name":"O4-glycosyl-hydroxyproline","type":"exact"},{"name":"O4GlcNAcHyPro","type":"exact"},{"name":"alpha-2-(N-acetylamino)glucopyranosyl-4-hydroxyproline","type":"exact"}],"termid":"MOD:00758"}


id: GO:0031804
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a type 7 metabotropic glutamate receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled glutamate receptor binding","termid":"GO:0035256"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"type 7 metabotropic glutamate receptor binding","synonyms":[{"name":"type 7 metabotropic glutamate receptor ligand","type":"narrow"}],"termid":"GO:0031804"}


id: GO:0032536
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that modulates the size of a cell projection.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular component size","termid":"GO:0032535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cell projection size","termid":"GO:0032536"}


id: GO:1901375
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of an acetate ester from one side of a membrane to the other.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane transporter activity","termid":"GO:0022857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"acetate ester transmembrane transporter activity","termid":"GO:1901375"}


id: GO:0006194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process of introducing a phosphate group into dIDP, deoxyinosine diphosphate, to produce dITP.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete dIDP phosphorylation (obsolete GO:0006194)","termid":"GO:0006194"}


id: SO:0001590
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence variant whereby at least one of the bases in the terminator codon is changed.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coding_sequence_variant","termid":"SO:0001580"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"terminator_codon_variant","secondary_identifiers":["loinc:LA6700-2","SO:0001625","http://vat.gersteinlab.org/formats.php"],"synonyms":[{"name":"VAT:endOverlap","type":"exact"},{"name":"terminal codon variant","type":"exact"},{"name":"terminal_codon_variant","type":"exact"},{"name":"terminator codon variant","type":"exact"}],"termid":"SO:0001590"}


id: PBO:0045850
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation elongation factor 1 alpha 1 pseudogene 40","termid":"PBO:0045850"}


id: MONDO:0019969
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Panner's disease is an osteochondrosis of the capitellum of the humerus, characterized by involvement of the dominant upper limb and onset before the age of 10 years. It results from lateral compression injuries of the elbow typically occurring in children practicing sports such as baseball and throw. It should be distinguished from osteochondritis dissecans of the capitellum, occurring later, in adolescents. Management is symptomatic and consists in reducing the activities of the affected elbow for a prolonged period of time. Prognosis is good.","definition_xrefs":["Orphanet:97336"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondrosis","termid":"MONDO:0018381"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"panner disease","secondary_identifiers":["MEDGEN:1673235","GARD:19365","UMLS:C4759831"],"synonyms":[{"name":"Osteochondrosis of the capital humerus","type":"exact"},{"name":"aseptic necrosis of the capital humerus","type":"exact"}],"termid":"MONDO:0019969","xrefs":{"Monarch":{"xref_id":"0019969"}}}


id: PBO:0043610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COMM domain containing 3","termid":"PBO:0043610"}


id: PBO:0079800
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP glucuronosyltransferase family 2 member B11","termid":"PBO:0079800"}


id: PBO:0076095
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syntaxin 1B","termid":"PBO:0076095"}


id: MONDO:0015633
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Bazex syndrome (obsolete MONDO:0015633)","termid":"MONDO:0015633","xrefs":{"Monarch":{"xref_id":"0015633"}}}


id: MONDO:0019970
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Sinding-Larsen-Johansson disease is a type of osteochondrosis affecting the attachment of the patellar tendon to the patella and characterized by tenderness and localized swelling of the patella.","definition_xrefs":["Orphanet:97337"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondrosis","termid":"MONDO:0018381"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sinding-Larsen-Johansson disease","secondary_identifiers":["GARD:19366","MEDGEN:1672493","icd11.foundation:1733785551","MedDRA:10063585","UMLS:C1504517"],"synonyms":[{"name":"Osteochondrosis of patella","type":"exact"},{"name":"aseptic necrosis of patella","type":"exact"}],"termid":"MONDO:0019970","xrefs":{"Monarch":{"xref_id":"0019970"}}}


id: MONDO:0021720
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete fetal alcohol spectrum disorders (obsolete MONDO:0021720)","termid":"MONDO:0021720","xrefs":{"Monarch":{"xref_id":"0021720"}}}


id: PBO:0084262
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Integral ER membrane protein that stimulates Sar1p GTPase activity; involved in COPII vesicle budding through disassociation of coat proteins from membranes onto liposomes; binds Sec16p; SED4 has a paralog, SEC12, that arose from the whole genome duplication","termid":"PBO:0084262"}


id: GO:1900211
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.","definition_xrefs":["GOC:yaf","PMID:17314325","GOC:mtg_apoptosis","GOC:TermGenie","GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of apoptotic process involved in development","termid":"GO:1904748"},{"relation_name":"is_a","term_name":"regulation of mesenchymal cell apoptotic process","termid":"GO:2001053"},{"relation_name":"regulates","term_name":"mesenchymal cell apoptotic process involved in metanephros development","termid":"GO:1900200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of mesenchymal cell apoptotic process involved in metanephros development","synonyms":[{"name":"regulation of mesenchymal cell apoptosis involved in metanephros development","type":"narrow"}],"termid":"GO:1900211"}


id: PBO:0000202
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcipressin (predicted)","termid":"PBO:0000202"}


id: GO:1900713
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"is_a","term_name":"regulation of secondary metabolite biosynthetic process","termid":"GO:1900376"},{"relation_name":"regulates","term_name":"violaceol I biosynthetic process","termid":"GO:1900590"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"regulation of violaceol I biosynthetic process","synonyms":[{"name":"regulation of violaceol I anabolism","type":"exact"},{"name":"regulation of violaceol I biosynthesis","type":"exact"},{"name":"regulation of violaceol I formation","type":"exact"},{"name":"regulation of violaceol I synthesis","type":"exact"}],"termid":"GO:1900713"}


id: SO:0001450
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A positively charged, hydorophilic amino acid encoded by the codons AAA and AAG.","direct_ancestors":[{"relation_name":"is_a","term_name":"amino_acid","termid":"SO:0001237"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysine","synonyms":[{"name":"K","type":"exact"},{"name":"Lys","type":"exact"}],"termid":"SO:0001450"}


id: GO:0023023
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a major histocompatibility complex.","definition_xrefs":["GOC:vw","GOC:mtg_signal"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex binding","termid":"GO:0044877"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"MHC protein complex binding","termid":"GO:0023023"}


id: PBO:0056027
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LSP1 pseudogene 5","termid":"PBO:0056027"}


id: PBO:0074710
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 74B","termid":"PBO:0074710"}


id: PBO:0078760
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA methyltransferase subunit 11-2 pseudogene 3","termid":"PBO:0078760"}


id: GO:0086038
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell.","definition_xrefs":["GOC:BHF","GOC:mtg_cardiac_conduct_nov11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"calcium:sodium antiporter activity","termid":"GO:0005432"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential","termid":"GO:0086038"}


id: MONDO:0700262
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any type 1 interferonopathies in which the cause of the disease is a variation in the IFIH1 gene. Individuals with variants in IFIH1 can present with a variety of phenotypes, including Aicardi-Goutieres syndrome and singleton-Merten syndrome.","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"type 1 interferonopathy","termid":"MONDO:0700264"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IFIH1-related type 1 interferonopathy","termid":"MONDO:0700262","xrefs":{"Monarch":{"xref_id":"0700262"}}}


id: PBO:0005891
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA Tryptophan, mitochondrial","termid":"PBO:0005891"}


id: GO:0034281
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate.","definition_xrefs":["PMID:17141283"],"direct_ancestors":[{"relation_name":"is_a","term_name":"terpene synthase activity","termid":"GO:0010333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"ent-isokaurene synthase activity","termid":"GO:0034281"}


id: PBO:0014286
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pombe cyclin C Homology","termid":"PBO:0014286"}


id: FYPO:0005045
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased, and sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation.","definition_xrefs":["PomBase:mah","PMID:20935472"],"direct_ancestors":[{"relation_name":"has_part","term_name":"lagging mitotic chromosomes","termid":"FYPO:0000228"},{"relation_name":"has_part","term_name":"decreased rate of mitotic spindle elongation","termid":"FYPO:0003268"},{"relation_name":"is_a","term_name":"decreased rate of mitotic spindle elongation","termid":"FYPO:0003268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0000337"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000337"},{"rel_name":"has_part","termid":"FYPO:0000054"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"part_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000337"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000631"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000337","FYPO:0000054","FYPO:0000631","FYPO:0001320","FYPO:0000641","FYPO:0000002"],"is_obsolete":false,"name":"abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation","synonyms":[{"name":"abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation during vegetative growth","type":"exact"},{"name":"abnormal sister chromatid segregation with lagging chromosomes and decreased rate of spindle elongation during mitotic cell cycle","type":"related"},{"name":"lagging mitotic chromosomes with decreased rate of mitotic spindle elongation","type":"exact"},{"name":"lagging mitotic chromosomes with decreased spindle elongation rate","type":"exact"},{"name":"lagging mitotic sister chromatids, with decreased rate of mitotic spindle elongation","type":"exact"}],"termid":"FYPO:0005045"}


id: GO:0004985
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein.","definition_xrefs":["GOC:ai","GOC:bf","PMID:20494127"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor activity","termid":"GO:0004930"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"G protein-coupled opioid receptor activity","synonyms":[{"name":"opioid receptor activity","type":"broad"}],"termid":"GO:0004985"}


id: MONDO:0009615
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency is a rare inborn error of metabolism disease characterized by mild to moderate, persistent elevation of methylmalonic acid in plasma, urine and cerebrospinal fluid. Clinical presentation may include acute metabolic decompensation with metabolic acidosis (presenting with vomiting, dehydration, confusion, hallucinations), nonspecific neurological symptoms, or may also be asymptomatic.","definition_xrefs":["Orphanet:308425"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methylmalonic acidemia","termid":"MONDO:0002012"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency","secondary_identifiers":["SCTID:765137006","GARD:17390","MEDGEN:344419","MESH:C565386","OMIM:251120","UMLS:C1855100"],"synonyms":[{"name":"MCEE deficiency","type":"exact"},{"name":"methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency","type":"exact"},{"name":"methylmalonic acidemia due to methylmalonyl-CoA racemase deficiency","type":"exact"},{"name":"methylmalonic aciduria III","type":"related"},{"name":"methylmalonic aciduria III, formerly","type":"related"},{"name":"methylmalonic aciduria due to methylmalonyl-CoA epimerase deficiency","type":"exact"},{"name":"methylmalonic aciduria due to methylmalonyl-CoA racemase deficiency","type":"exact"},{"name":"methylmalonyl-CoA epimerase deficiency","type":"related"},{"name":"methylmalonyl-Coa epimerase deficiency with sepiapterin reductase deficiency","type":"related"},{"name":"methylmalonyl-Coa racemase deficiency","type":"related"}],"termid":"MONDO:0009615","xrefs":{"Monarch":{"xref_id":"0009615"}}}


id: GO:0160036
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of postsynaptic density assembly.","definition_xrefs":["PMID:17626212"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of postsynaptic density assembly","termid":"GO:0099151"},{"relation_name":"is_a","term_name":"positive regulation of organelle assembly","termid":"GO:1902117"},{"relation_name":"is_a","term_name":"positive regulation of postsynaptic density organization","termid":"GO:1905876"},{"relation_name":"positively_regulates","term_name":"postsynaptic density assembly","termid":"GO:0097107"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"positive regulation of postsynaptic density assembly","termid":"GO:0160036"}


id: PBO:0091715
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human PSMC1","termid":"PBO:0091715"}


id: PBO:0067932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 234","termid":"PBO:0067932"}


id: PBO:0054553
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1954","termid":"PBO:0054553"}


id: PR:Q9UUG0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- fas1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UUG0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fatty acid synthase subunit beta (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC926.09c","synonyms":[{"name":"Spom972h-fas1","type":"exact"}],"termid":"PR:Q9UUG0"}


id: FYPO:0000787
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone H3-K9 methylation during vegetative growth","termid":"FYPO:0000458"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0002274","FYPO:0001985","FYPO:0002494"],"is_obsolete":false,"name":"abnormal histone H3-K9 trimethylation during vegetative growth","synonyms":[{"name":"abnormal histone H3 K9 trimethylation during vegetative growth","type":"exact"},{"name":"abnormal histone H3-K9 trimethylation during mitotic cell cycle","type":"related"},{"name":"abnormal histone H3K9 trimethylation during vegetative growth","type":"exact"},{"name":"abnormal histone H3K9me3 during vegetative growth","type":"exact"},{"name":"abnormal histone lysine H3 K9 trimethylation during vegetative growth","type":"exact"}],"termid":"FYPO:0000787"}


id: PBO:0087370
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Spt4p/5p (DSIF) transcription elongation factor complex subunit; the Spt4/5 complex binds to ssRNA in a sequence-specific manner, and along with RNAP I and II has multiple roles regulating transcriptional elongation, RNA processing, quality control, and transcription-coupled repair; localizes to kinetochores and heterochromatin, influencing chromosomal dynamics and silencing; required for transcription through long trinucleotide repeats in ORFs and non-protein coding regions","termid":"PBO:0087370"}


id: GO:1902542
data:
  {"annotated_genes":["SJAG_00883"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[107545],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902543"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.","definition_xrefs":["GOC:TermGenie","PMID:22809626"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein localization to spindle pole body","termid":"GO:1902363"},{"relation_name":"regulates","term_name":"protein localization to mitotic spindle pole body","termid":"GO:1902440"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00883":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of protein localization to mitotic spindle pole body","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"regulation of protein localisation to mitotic spindle pole body","type":"exact"}],"termid":"GO:1902542","terms_by_termid":{"GO:1902543":null}}


id: PBO:0071561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L35a pseudogene 27","termid":"PBO:0071561"}


id: PBO:0075086
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 136","termid":"PBO:0075086"}


id: PBO:0070820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 50","termid":"PBO:0070820"}


id: FYPO:0006704
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sedoheptulose-7-phosphate measured in the cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell during vegetative growth","termid":"FYPO:0001329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased cellular sedoheptulose-7-phosphate level","synonyms":[{"name":"decreased cellular sedoheptulose-7-phosphate level during mitotic cell cycle","type":"related"},{"name":"decreased cellular sedoheptulose-7-phosphate level during vegetative growth","type":"exact"},{"name":"reduced cellular sedoheptulose-7-phosphate level","type":"exact"}],"termid":"FYPO:0006704"}


id: PBO:0051542
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IL6R antisense RNA 1","termid":"PBO:0051542"}


id: MONDO:0957317
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hematuria, benign familial","secondary_identifiers":["MEDGEN:66039","DOID:0111365","OMIMPS:141200","MESH:C562476","Orphanet:97562","UMLS:C0241908"],"termid":"MONDO:0957317","xrefs":{"Monarch":{"xref_id":"0957317"}}}


id: GO:0046261
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrotoluene, 1-methyl-4-nitrobenzene.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete 4-nitrotoluene biosynthetic process (obsolete GO:0046261)","synonyms":[{"name":"4-nitrotoluene anabolism","type":"exact"},{"name":"4-nitrotoluene biosynthesis","type":"exact"},{"name":"4-nitrotoluene biosynthetic process","type":"exact"},{"name":"4-nitrotoluene formation","type":"exact"},{"name":"4-nitrotoluene synthesis","type":"exact"},{"name":"4NT biosynthesis","type":"exact"},{"name":"4NT biosynthetic process","type":"exact"}],"termid":"GO:0046261"}


id: MOD:01652
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that is produced by formation of an adduct with a sulfonyl halide compound used as a reagent.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reagent derivatized residue","termid":"MOD:00848"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulfonyl halide reagent derivatized residue","termid":"MOD:01652"}


id: GO:1904813
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.","definition_xrefs":["PMID:23650620","GOC:TermGenie","GO_REF:0000064"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular organelle lumen","termid":"GO:0070013"},{"relation_name":"part_of","term_name":"ficolin-1-rich granule","termid":"GO:0101002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0031410"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0031410"],"is_obsolete":false,"name":"ficolin-1-rich granule lumen","synonyms":[{"name":"ficolin-1-rich granule membrane-enclosed lumen","type":"exact"},{"name":"membrane-enclosed lumen of ficolin granule","type":"related"},{"name":"membrane-enclosed lumen of ficolin-1 rich granule","type":"exact"},{"name":"membrane-enclosed lumen of ficolin-1-rich granule","type":"exact"}],"termid":"GO:1904813"}


id: GO:0050856
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of antigen receptor-mediated signaling pathway","termid":"GO:0050854"},{"relation_name":"regulates","term_name":"T cell receptor signaling pathway","termid":"GO:0050852"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of T cell receptor signaling pathway","synonyms":[{"name":"regulation of T lymphocyte receptor signaling pathway","type":"exact"},{"name":"regulation of T lymphocyte receptor signalling pathway","type":"exact"},{"name":"regulation of T-cell receptor signaling pathway","type":"exact"},{"name":"regulation of T-cell receptor signalling pathway","type":"exact"},{"name":"regulation of T-lymphocyte receptor signaling pathway","type":"exact"},{"name":"regulation of T-lymphocyte receptor signalling pathway","type":"exact"},{"name":"regulation of TCR signaling pathway","type":"exact"}],"termid":"GO:0050856"}


id: MONDO:0013527
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any lissencephaly in which the cause of the disease is a mutation in the NDE1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microlissencephaly","termid":"MONDO:0015204"},{"relation_name":"is_a","term_name":"microcephaly with lissencephaly and/or hydranencephaly","termid":"MONDO:0700116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0002320"],"is_obsolete":false,"name":"lissencephaly 4","secondary_identifiers":["MEDGEN:462811","OMIM:614019","UMLS:C3151461","DOID:0112235"],"synonyms":[{"name":"LIS4","type":"related"},{"name":"NDE1 lissencephaly (disease)","type":"exact"},{"name":"lissencephaly (disease) caused by mutation in NDE1","type":"exact"},{"name":"lissencephaly 4","type":"exact"},{"name":"lissencephaly 4 (with microcephaly)","type":"exact"},{"name":"lissencephaly 4 with microcephaly","type":"related"},{"name":"lissencephaly 4, with microcephaly","type":"related"},{"name":"lissencephaly type 4","type":"exact"}],"termid":"MONDO:0013527","xrefs":{"Monarch":{"xref_id":"0013527"}}}


id: GO:0098993
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.","definition_xrefs":["GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete anchored component of synaptic vesicle membrane (obsolete GO:0098993)","termid":"GO:0098993"}


id: MONDO:0018523
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-metastasizing cystic epithelial neoplasm arising from the exocrine pancreas. It is composed of columnar, mucin-producing epithelial cells. It occurs almost exclusively in women. Large tumors are often accompanied by a palpable abdominal mass.","definition_xrefs":["NCIT:C5718"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreatic cystadenoma","termid":"MONDO:0002809"},{"relation_name":"is_a","term_name":"exocrine pancreatic carcinoma","termid":"MONDO:0005192"},{"relation_name":"is_a","term_name":"mucinous cystadenoma","termid":"MONDO:0006859"},{"relation_name":"is_a","term_name":"mucin-producing carcinoma","termid":"MONDO:0020596"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"pancreatic mucinous cystadenoma","secondary_identifiers":["MEDGEN:277492","DOID:7235","Orphanet:424053","GARD:21778","UMLS:C1335309","DOID:7735"],"synonyms":[{"name":"colloid cystadenoma of pancreas","type":"related"},{"name":"colloid cystadenoma of the pancreas","type":"related"},{"name":"colloidal cystadenoma of pancreas","type":"related"},{"name":"colloidal cystadenoma of the pancreas","type":"related"},{"name":"mucinous cystadenocarcinoma of the pancreas","type":"related"},{"name":"mucinous cystadenoma of pancreas","type":"exact"},{"name":"mucinous cystadenoma of the pancreas","type":"related"},{"name":"pancreas mucinous cystadenoma","type":"exact"},{"name":"pancreatic colloid cystadenoma","type":"related"},{"name":"pancreatic colloidal cystadenoma","type":"related"},{"name":"pancreatic mucinous cystadenocarcinoma","type":"related"},{"name":"pancreatic mucinous cystadenoma","type":"exact"},{"name":"pancreatic mucinous cystic neoplasm","type":"related"}],"termid":"MONDO:0018523","xrefs":{"Monarch":{"xref_id":"0018523"}}}


id: GO:0031926
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic anion transmembrane transporter activity","termid":"GO:0008514"},{"relation_name":"is_a","term_name":"organophosphate ester transmembrane transporter activity","termid":"GO:0015605"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"pyridoxal phosphate transmembrane transporter activity","termid":"GO:0031926"}


id: PBO:0044574
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dopamine beta-hydroxylase","termid":"PBO:0044574"}


id: GO:1904049
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.","definition_xrefs":["PMID:22314364","GO_REF:0000058","GOC:pad","GOC:PARL","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of neurotransmitter secretion","termid":"GO:0046929"},{"relation_name":"is_a","term_name":"regulation of spontaneous neurotransmitter secretion","termid":"GO:1904048"},{"relation_name":"negatively_regulates","term_name":"spontaneous neurotransmitter secretion","termid":"GO:0061669"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of spontaneous neurotransmitter secretion","synonyms":[{"name":"down regulation of spontaneous neurotransmitter secretion","type":"exact"},{"name":"down regulation of stimulus-independent neurotransmitter secretion","type":"exact"},{"name":"down-regulation of spontaneous neurotransmitter secretion","type":"exact"},{"name":"down-regulation of stimulus-independent neurotransmitter secretion","type":"exact"},{"name":"downregulation of spontaneous neurotransmitter secretion","type":"exact"},{"name":"downregulation of stimulus-independent neurotransmitter secretion","type":"exact"},{"name":"inhibition of spontaneous neurotransmitter secretion","type":"narrow"},{"name":"inhibition of stimulus-independent neurotransmitter secretion","type":"narrow"},{"name":"negative regulation of stimulus-independent neurotransmitter secretion","type":"exact"}],"termid":"GO:1904049"}


id: GO:0000459
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete exonucleolytic trimming involved in rRNA processing (obsolete GO:0000459)","synonyms":[{"name":"exonucleolytic trimming during rRNA processing","type":"related"}],"termid":"GO:0000459"}


id: PBO:0054037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1372","termid":"PBO:0054037"}


id: MONDO:0001749
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A senile cataract that involves the lens cortex.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"senile cataract","termid":"MONDO:0004847"},{"relation_name":"is_a","term_name":"cortical cataract","termid":"MONDO:0045051"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cortical senile cataract","secondary_identifiers":["MEDGEN:509748","DOID:13574","ICD9:366.15","UMLS:C0154980","SCTID:78875003"],"synonyms":[{"name":"cortical senile cataract","type":"exact"},{"name":"lens cortex senile cataract","type":"exact"},{"name":"senile cataract of lens cortex","type":"exact"}],"termid":"MONDO:0001749","xrefs":{"Monarch":{"xref_id":"0001749"}}}


id: PBO:0113047
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Chromosome linkage inner nuclear membrane protein; CLIP, involved in perinuclear chromosome tethering and rDNA repeat stability; enriched at telomeres and subtelomeric regions; associates with and regulates subtelomeric genes, interacting with TREX (transcription export) factors; produces two splice variants with different functions; alternative splicing of SRC1 pre-mRNA is promoted by Hub1p; mutant is aneuploidy tolerant; SRC1 has a paralog, HEH2, that arose from the whole genome duplication","termid":"PBO:0113047"}


id: PBO:0031087
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-gene_expression_regulation_phenotype","termid":"PBO:0031087"}


id: PBO:0049130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein regulated inducer of neurite outgrowth 1","termid":"PBO:0049130"}


id: PBO:0079225
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetratricopeptide repeat domain 3 pseudogene 1","termid":"PBO:0079225"}


id: PBO:0080854
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"YEATS2 antisense RNA 1","termid":"PBO:0080854"}


id: PBO:0044523
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DAB2 interacting protein","termid":"PBO:0044523"}


id: GO:0061682
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of a seminal vesicle are generated and organized.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gland morphogenesis","termid":"GO:0022612"},{"relation_name":"part_of","term_name":"seminal vesicle development","termid":"GO:0061107"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"seminal vesicle morphogenesis","termid":"GO:0061682"}


id: PBO:0015217
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by D. melanogaster twine","termid":"PBO:0015217"}


id: PBO:0004595
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4.2.1.1","termid":"PBO:0004595"}


id: PBO:0046413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epithelial mitogen","termid":"PBO:0046413"}


id: GO:0141161
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cAMP/PKA signal transduction.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of intracellular signal transduction","termid":"GO:1902531"},{"relation_name":"regulates","term_name":"cAMP/PKA signal transduction","termid":"GO:0141156"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of cAMP/PKA signal transduction","synonyms":[{"name":"regulation of cAMP/PKA signaling","type":"exact"}],"termid":"GO:0141161"}


id: PBO:0036121
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_onset_of_actomyosin_contractile_ring_assembly","termid":"PBO:0036121"}


id: MONDO:1012284
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Stomach ulcer that occurs in pigs.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stomach ulcer, non-human animal","termid":"MONDO:1011662"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stomach ulcer, pig","secondary_identifiers":["OMIA:001027-9823"],"termid":"MONDO:1012284","xrefs":{"Monarch":{"xref_id":"1012284"}}}


id: MONDO:0020541
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An aggressive granulosa cell tumor that arises from the ovary and metastasizes to other anatomic sites.","definition_xrefs":["NCIT:C8403"],"direct_ancestors":[{"relation_name":"is_a","term_name":"malignant sex cord stromal tumor of ovary","termid":"MONDO:0018172"},{"relation_name":"is_a","term_name":"malignant endocrine neoplasm","termid":"MONDO:0021069"},{"relation_name":"is_a","term_name":"ovarian granulosa cell tumor","termid":"MONDO:0023283"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"maligant granulosa cell tumor of ovary","secondary_identifiers":["icd11.foundation:148207042","Orphanet:99915","SCTID:254861002","UMLS:C0346175","MEDGEN:138043","GARD:19707"],"synonyms":[{"name":"GCT of the ovary","type":"related"},{"name":"GTCT","type":"related"},{"name":"Maligant granulosa cell tumor of the ovary","type":"related"},{"name":"Maligant granulosa cell tumour of the ovary","type":"related"},{"name":"adult granulosa cell tumor of the ovary","type":"related"},{"name":"adult granulosa cell tumour of the ovary","type":"related"},{"name":"adult ovarian granulosa cell tumor","type":"exact"},{"name":"adult ovarian granulosa cell tumour","type":"exact"},{"name":"cancer of granulosa cell","type":"exact"},{"name":"granulosa cell cancer","type":"exact"},{"name":"granulosa cell malignant tumor","type":"exact"},{"name":"granulosa cell malignant tumour","type":"exact"},{"name":"granulosa theca cell tumor","type":"related"},{"name":"granulosa theca cell tumor of the ovary","type":"related"},{"name":"granulosa theca cell tumour","type":"related"},{"name":"granulosa theca cell tumour of the ovary","type":"related"},{"name":"malignant granulosa cell neoplasm","type":"exact"},{"name":"malignant granulosa cell neoplasm of ovary","type":"exact"},{"name":"malignant granulosa cell neoplasm of the ovary","type":"exact"},{"name":"malignant granulosa cell tumor of ovary","type":"exact"},{"name":"malignant granulosa cell tumor of the ovary","type":"exact"},{"name":"malignant granulosa cell tumour of ovary","type":"exact"},{"name":"malignant granulosa cell tumour of the ovary","type":"exact"},{"name":"malignant ovarian granulosa cell neoplasm","type":"exact"},{"name":"malignant ovarian granulosa cell tumor","type":"exact"},{"name":"malignant ovarian granulosa cell tumour","type":"exact"},{"name":"ovarian granulosa cell tumor of adults","type":"exact"},{"name":"ovarian granulosa cell tumour of adults","type":"exact"}],"termid":"MONDO:0020541","xrefs":{"Monarch":{"xref_id":"0020541"}}}


id: PBO:0054850
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2264","termid":"PBO:0054850"}


id: PBO:0090082
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SRP-independent ER targeting protein Snd2","termid":"PBO:0090082"}


id: PBO:0055726
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LMNTD2 antisense RNA 1","termid":"PBO:0055726"}


id: SO:0001941
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A kind of histone modification site, whereby the 91st residue (a lysine), from the start of the H4 histone protein is acetylated.","definition_xrefs":["EBI:nj"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone_4_acetylation_site","termid":"SO:0001972"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"H4K91_acetylation_site","synonyms":[{"name":"H4K91 acetylation site","type":"exact"},{"name":"H4K91ac","type":"exact"}],"termid":"SO:0001941"}


id: PBO:0075559
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPG7 matrix AAA peptidase subunit, paraplegin","termid":"PBO:0075559"}


id: PBO:0003682
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DASH complex subunit Ask1","termid":"PBO:0003682"}


id: MONDO:0016885
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of chromosome 3","termid":"MONDO:0016868"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial deletion of the short arm of chromosome 3","secondary_identifiers":["Orphanet:261875","UMLS:C5679666","icd11.foundation:551346575","MEDGEN:1826020","GARD:37"],"synonyms":[{"name":"partial deletion of chromosome 3p","type":"exact"},{"name":"partial deletion of the short arm of chromosome type 3","type":"exact"},{"name":"partial monosomy of chromosome 3p","type":"exact"},{"name":"partial monosomy of the short arm of chromosome 3","type":"exact"}],"termid":"MONDO:0016885","xrefs":{"Monarch":{"xref_id":"0016885"}}}


id: PBO:0085453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Possible shared subunit of Cop9 signalosome (CSN) and eIF3; binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain","termid":"PBO:0085453"}


id: GO:1901806
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of beta-glucoside.","definition_xrefs":["GOC:yaf","PMID:16390337","PMID:8990303","GOC:TermGenie","PMID:15205427","Unipathway:UPA00237"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycoside biosynthetic process","termid":"GO:0016138"},{"relation_name":"is_a","term_name":"beta-glucoside metabolic process","termid":"GO:1901804"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"beta-glucoside biosynthetic process","synonyms":[{"name":"beta-glucoside anabolism","type":"exact"},{"name":"beta-glucoside biosynthesis","type":"exact"},{"name":"beta-glucoside formation","type":"exact"},{"name":"beta-glucoside synthesis","type":"exact"}],"termid":"GO:1901806"}


id: MONDO:0026723
data:
  {"annotated_genes":["SJAG_04616"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86261],"is_not":false,"summary":null,"term":"MONDO:0026723"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic X-linked intellectual disability","termid":"MONDO:0019181"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04616":null},"genotype_count":0,"is_obsolete":false,"name":"intellectual developmental disorder, X-linked 108","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1680544","UMLS:C5193009","OMIM:301024","DOID:0111844"],"synonyms":[{"name":"INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED 108","type":"related"},{"name":"MRX108","type":"related"},{"name":"Mental Retardation, X-Linked 108","type":"related"},{"name":"intellectual developmental disorder, X-linked 108, X-linked recessive","type":"exact"}],"termid":"MONDO:0026723","terms_by_termid":{"MONDO:0026723":null},"xrefs":{"Monarch":{"xref_id":"0026723"}}}


id: FYPO:0002707
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cordycepin.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0002057","FYPO:0002060","FYPO:0000003","FYPO:0002058","FYPO:0000139"],"is_obsolete":false,"name":"normal growth on cordycepin","synonyms":[{"name":"normal cell population growth in presence of cordycepin","type":"exact"},{"name":"normal cell population growth on cordycepin","type":"exact"},{"name":"normal cellular response to cordycepin","type":"related"},{"name":"normal vegetative cell population growth on cordycepin","type":"exact"}],"termid":"FYPO:0002707"}


id: MONDO:0032799
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial DNA depletion syndrome","termid":"MONDO:0018158"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069"],"is_obsolete":false,"name":"mitochondrial DNA depletion syndrome 16 (hepatic type)","secondary_identifiers":["UMLS:C5193142","OMIM:618528","MEDGEN:1684495","DOID:0070446"],"synonyms":[{"name":"MITOCHONDRIAL DNA DEPLETION SYNDROME 16 (HEPATIC TYPE)","type":"related"},{"name":"MTDPS16","type":"related"}],"termid":"MONDO:0032799","xrefs":{"Monarch":{"xref_id":"0032799"}}}


id: GO:0036286
data:
  {"annotated_genes":["SJAG_02626","SJAG_02707","SJAG_02087"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[70150,71724,92240],"is_not":false,"summary":null,"term":"GO:0036286"}]},"cv_name":"cellular_component","definition":"A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.","definition_xrefs":["GOC:vw","PMID:21900489","PMID:23722945"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"cortical cytoskeleton","termid":"GO:0030863"},{"relation_name":"part_of","term_name":"eisosome","termid":"GO:0032126"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02087":null,"SJAG_02626":null,"SJAG_02707":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005938"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005938","GO:0005737"],"is_obsolete":false,"name":"eisosome filament","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"linear eisosome","type":"exact"}],"termid":"GO:0036286","terms_by_termid":{"GO:0036286":null}}


id: PBO:0005495
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AP endonuclease Apn1","termid":"PBO:0005495"}


id: PBO:0069972
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1267, pseudogene","termid":"PBO:0069972"}


id: GO:0070356
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).","definition_xrefs":["PMID:7654227"],"direct_ancestors":[{"relation_name":"is_a","term_name":"SNARE complex","termid":"GO:0031201"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0032991"],"is_obsolete":false,"name":"synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex","synonyms":[{"name":"SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2)","type":"narrow"},{"name":"STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2 complex","type":"narrow"}],"termid":"GO:0070356"}


id: PBO:0043899
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cysteine rich protein 3","termid":"PBO:0043899"}


id: PBO:0042895
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"craniofacial development protein 1","termid":"PBO:0042895"}


id: GO:0045066
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"T cell differentiation","termid":"GO:0030217"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulatory T cell differentiation","synonyms":[{"name":"regulatory T cell development","type":"related"},{"name":"regulatory T lymphocyte differentiation","type":"exact"},{"name":"regulatory T-cell differentiation","type":"exact"},{"name":"regulatory T-lymphocyte differentiation","type":"exact"},{"name":"suppressor T cell differentiation","type":"exact"},{"name":"suppressor T lymphocyte differentiation","type":"exact"},{"name":"suppressor T-cell differentiation","type":"exact"},{"name":"suppressor T-lymphocyte differentiation","type":"exact"}],"termid":"GO:0045066"}


id: MONDO:0014223
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the ERBB4 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial amyotrophic lateral sclerosis","termid":"MONDO:0005144"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"amyotrophic lateral sclerosis type 19","secondary_identifiers":["MEDGEN:811607","DOID:0060210","GARD:15980","OMIM:615515","UMLS:C3715155"],"synonyms":[{"name":"ALS19","type":"exact"},{"name":"ERBB4 amyotrophic lateral sclerosis","type":"exact"},{"name":"amyotrophic lateral sclerosis 19","type":"exact"},{"name":"amyotrophic lateral sclerosis caused by mutation in ERBB4","type":"exact"},{"name":"amyotrophic lateral sclerosis type 19","type":"exact"}],"termid":"MONDO:0014223","xrefs":{"Monarch":{"xref_id":"0014223"}}}


id: PBO:0108947
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Spi-C transcription factor pseudogene 4","termid":"PBO:0108947"}


id: PBO:0051481
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin lambda variable (VI)-22-1 (pseudogene)","termid":"PBO:0051481"}


id: PBO:0052950
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinase suppressor of ras 1 pseudogene 1","termid":"PBO:0052950"}


id: GO:0032420
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.","definition_xrefs":["PMID:15661519","GOC:ecd","PMID:7840137"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron projection","termid":"GO:0043005"},{"relation_name":"is_a","term_name":"actin-based cell projection","termid":"GO:0098858"},{"relation_name":"part_of","term_name":"stereocilium bundle","termid":"GO:0032421"},{"relation_name":"part_of","term_name":"organelle","termid":"GO:0043226"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"stereocilium","termid":"GO:0032420"}


id: GO:0016286
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.","definition_xrefs":["OMIM:602754","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"calcium-activated potassium channel activity","termid":"GO:0015269"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"small conductance calcium-activated potassium channel activity","synonyms":[{"name":"SK KCa channels","type":"exact"},{"name":"SK calcium-activated potassium channel activity","type":"exact"},{"name":"small conductance KCa channels","type":"exact"}],"termid":"GO:0016286"}


id: GO:0045773
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of axon extension.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell growth","termid":"GO:0030307"},{"relation_name":"is_a","term_name":"regulation of axon extension","termid":"GO:0030516"},{"relation_name":"is_a","term_name":"positive regulation of developmental growth","termid":"GO:0048639"},{"relation_name":"is_a","term_name":"positive regulation of axonogenesis","termid":"GO:0050772"},{"relation_name":"positively_regulates","term_name":"axon extension","termid":"GO:0048675"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of axon extension","synonyms":[{"name":"activation of axon extension","type":"narrow"},{"name":"stimulation of axon extension","type":"narrow"},{"name":"up regulation of axon extension","type":"exact"},{"name":"up-regulation of axon extension","type":"exact"},{"name":"upregulation of axon extension","type":"exact"}],"termid":"GO:0045773"}


id: GO:0061037
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"is_a","term_name":"regulation of cartilage development","termid":"GO:0061035"},{"relation_name":"negatively_regulates","term_name":"cartilage development","termid":"GO:0051216"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of cartilage development","termid":"GO:0061037"}


id: _global:causally_upstream_of,_negative_effect
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.","direct_ancestors":[{"relation_name":"is_a","term_name":"causally_upstream_of","termid":"_global:causally_upstream_of"},{"relation_name":"is_a","term_name":"causally_upstream_of_or_within,_negative_effect","termid":"_global:causally_upstream_of_or_within,_negative_effect"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"causally_upstream_of,_negative_effect","secondary_identifiers":["RO:0002305"],"termid":"_global:causally_upstream_of,_negative_effect"}


id: MONDO:0100106
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A form of age-related epileptic encephalopathy, characterized by the onset of seizures within the first 4 weeks of life that can be generalized or lateralized, independent of the sleep cycle, and that can result in frequent seizures per day, leading to psychomotor impairment and death.","gene_count":0,"genotype_count":0,"name":"obsolete neonatal epileptic encephalopathy (obsolete MONDO:0100106)","termid":"MONDO:0100106","xrefs":{"Monarch":{"xref_id":"0100106"}}}


id: GO:1901361
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete organic cyclic compound catabolic process (obsolete GO:1901361)","synonyms":[{"name":"organic cyclic compound breakdown","type":"exact"},{"name":"organic cyclic compound catabolism","type":"exact"},{"name":"organic cyclic compound degradation","type":"exact"}],"termid":"GO:1901361"}


id: PBO:0057976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3691","termid":"PBO:0057976"}


id: MONDO:0007054
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acromial dimples","secondary_identifiers":["MEDGEN:869278","OMIM:102350","UMLS:C4023704"],"synonyms":[{"name":"acromial dimples","type":"exact"},{"name":"supraspinous fossae, congenital","type":"related"}],"termid":"MONDO:0007054","xrefs":{"Monarch":{"xref_id":"0007054"}}}


id: MONDO:0014797
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"lymphatic malformation","termid":"MONDO:0019313"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"lymphatic malformation 6","secondary_identifiers":["OMIM:616843","UMLS:C4225184","MEDGEN:908120"],"synonyms":[{"name":"LMPH3","type":"exact"},{"name":"generalised lymphatic dysplasia of Fotiou","type":"related"},{"name":"generalized lymphatic dysplasia of Fotiou","type":"related"},{"name":"lymphedema, hereditary, 3","type":"related"},{"name":"lymphedema, hereditary, III","type":"exact"},{"name":"lymphedema, hereditary, type III","type":"exact"}],"termid":"MONDO:0014797","xrefs":{"Monarch":{"xref_id":"0014797"}}}


id: FYPO:0002872
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of the endoplasmic reticulum (ER) is abnormal. In fission yeast, the ER is normally located in the cell cortex and tethered to the plasma membrane.","definition_xrefs":["PomBase:mah","PMID:23041194"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal endoplasmic reticulum organization","termid":"FYPO:0000805"},{"relation_name":"is_a","term_name":"abnormal organelle localization","termid":"FYPO:0006329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0000138","FYPO:0000002"],"is_obsolete":false,"name":"abnormal endoplasmic reticulum localization","synonyms":[{"name":"abnormal ER localization","type":"exact"},{"name":"abnormal endoplasmic reticulum localisation","type":"exact"},{"name":"abnormal endoplasmic reticulum localization during mitotic cell cycle","type":"related"},{"name":"abnormal endoplasmic reticulum localization during vegetative growth","type":"exact"}],"termid":"FYPO:0002872"}


id: PBO:0071232
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 73","termid":"PBO:0071232"}


id: MONDO:0018964
data:
  {"annotated_genes":["SJAG_04042","SJAG_04425","SJAG_04459"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85601,85602],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009354"},{"annotations":[86211],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009609"}]},"cv_name":"mondo","definition":"Homocystinuria without methylmalonic aciduria is an inborn error of vitamin B12 (cobalamin) metabolism characterized by megaloblastic anemia, encephalopathy and, sometimes, developmental delay, and associated with homocystinuria and hyperhomocysteinemia. There are three types of homocystinuria without methylmalonic aciduria; cblE, cblG and cblD-variant 1 (cblDv1).","definition_xrefs":["Orphanet:622"],"direct_ancestors":[{"relation_name":"is_a","term_name":"homocystinuria","termid":"MONDO:0004737"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"hereditary anemia","termid":"MONDO:0016624"},{"relation_name":"is_a","term_name":"inborn disorder of cobalamin metabolism and transport","termid":"MONDO:0019220"}],"gene_count":3,"genes_by_uniquename":{"SJAG_04042":null,"SJAG_04425":null,"SJAG_04459":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005066","MONDO:0004736","MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"homocystinuria without methylmalonic aciduria","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C4303479","icd11.foundation:726186034","MEDGEN:929148","GARD:16537","SCTID:721225009"],"synonyms":[{"name":"functional methionine synthase deficiency","type":"exact"},{"name":"homocystinuria without methylmalonic aciduria","type":"exact"},{"name":"methylcobalamin deficiency","type":"exact"}],"termid":"MONDO:0018964","terms_by_termid":{"MONDO:0009354":null,"MONDO:0009609":null},"xrefs":{"Monarch":{"xref_id":"0018964"}}}


id: MONDO:0017318
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"hyperpigmentation of the skin","termid":"MONDO:0019289"},{"relation_name":"is_a","term_name":"developmental defect during embryogenesis","termid":"MONDO:0019755"},{"relation_name":"is_a","term_name":"neurocutaneous syndrome","termid":"MONDO:0042983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328","MONDO:0005093"],"is_obsolete":false,"name":"phakomatosis pigmentovascularis","secondary_identifiers":["MEDGEN:220888","GARD:4312","ICD9:709.09","Orphanet:2875","UMLS:C1274879","MESH:C537894","icd11.foundation:1768130414","SCTID:403545005"],"synonyms":[{"name":"PPv","type":"related"},{"name":"Phacomatosis pigmentovascularis","type":"related"},{"name":"association of cutaneous vascular malformations and different pigmentary disorders","type":"related"},{"name":"phakomatosis pigmentovascularis","type":"exact"},{"name":"port-wine stain with oculocutaneous melanosis","type":"exact"}],"termid":"MONDO:0017318","xrefs":{"Monarch":{"xref_id":"0017318"}}}


id: PBO:0084161
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Highly-acidic RWD domain-containing cytoplasmic protein; forms a highly conserved complex with Rbg2p that is responsible for efficient cell growth under amino acid starvation and binds translational activator Gcn1p in dose-dependent manner according to stress level; associates with translating ribosomes; intrinsically unstructured protein whose stability is enhanced upon binding Rbg2p","termid":"PBO:0084161"}


id: PBO:0054325
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1718","termid":"PBO:0054325"}


id: MONDO:0043892
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A bacterial infection related to a device used to replace a missing body part. The infection may occur during the operation from direct contamination or post-operatively through hematogenous spread.","definition_xrefs":["NCIT:C79705"],"direct_ancestors":[{"relation_name":"is_a","term_name":"infectious disease","termid":"MONDO:0005550"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prosthesis-related infectious disease","secondary_identifiers":["MESH:D016459"],"synonyms":[{"name":"device related infection","type":"exact"},{"name":"infections, prosthesis-related","type":"related"},{"name":"prosthesis related infections","type":"related"},{"name":"prosthesis-related infection","type":"exact"}],"termid":"MONDO:0043892","xrefs":{"Monarch":{"xref_id":"0043892"}}}


id: GO:0043953
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein transmembrane transport","termid":"GO:0071806"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0055085","GO:0008150"],"is_obsolete":false,"name":"protein transport by the Tat complex","synonyms":[{"name":"protein secretion by the TAT complex","type":"narrow"},{"name":"protein translocation by the TAT complex","type":"narrow"},{"name":"protein translocation by the twin-arginine translocation complex","type":"narrow"},{"name":"twin-arginine translocation pathway","type":"exact"}],"termid":"GO:0043953"}


id: PBO:0060324
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myosin IC","termid":"PBO:0060324"}


id: GO:0010852
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binds to and decreases the activity of an enzyme that catalyzes a ring closure reaction.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme inhibitor activity","termid":"GO:0004857"},{"relation_name":"is_a","term_name":"cyclase regulator activity","termid":"GO:0010851"},{"relation_name":"negatively_regulates","term_name":"cyclase activity","termid":"GO:0009975"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0009975"},{"rel_name":"is_a","termid":"GO:0004857"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"negatively_regulates","termid":"GO:0003824"},{"rel_name":"regulates","termid":"GO:0009975"},{"rel_name":"is_a","termid":"GO:0140678"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"regulates","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0009975","GO:0004857","GO:0098772","GO:0140678","GO:0030234","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"cyclase inhibitor activity","termid":"GO:0010852"}


id: PBO:0004518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deoxycytidylate deaminase (predicted)","termid":"PBO:0004518"}


id: PBO:0056692
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotic double-stranded break formation protein 4","termid":"PBO:0056692"}


id: GO:0046975
data:
  {"annotated_genes":["SJAG_01193","SJAG_02873"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[78949],"is_not":false,"summary":null,"term":"GO:0046975"},{"annotations":[95817],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140954"},{"annotations":[64454],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140955"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group to the lysine residue at position 36 of the histone H3 protein.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-lysine N-methyltransferase activity","termid":"GO:0016279"},{"relation_name":"is_a","term_name":"histone H3 methyltransferase activity","termid":"GO:0140938"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01193":null,"SJAG_02873":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0008276"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0008276","GO:0016741","GO:0016740","GO:0140096"],"is_obsolete":false,"name":"histone H3K36 methyltransferase activity","references_by_uniquename":{"GO_REF:0000003":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"histone H3K36 methylase activity","type":"exact"},{"name":"histone lysine N-methyltransferase activity (H3-K36 specific)","type":"exact"},{"name":"histone methylase activity (H3-K36 specific)","type":"exact"},{"name":"histone methyltransferase activity (H3-K36 specific)","type":"exact"},{"name":"histone-H3K36 methyltransferase activity","type":"exact"}],"termid":"GO:0046975","terms_by_termid":{"GO:0046975":null,"GO:0140954":null,"GO:0140955":null}}


id: GO:1990788
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins.","definition_xrefs":["PMID:24311597","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"cytosol","termid":"GO:0005829"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005829"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005829","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"GLI-SUFU complex","termid":"GO:1990788"}


id: GO:0016463
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) = ADP + phosphate + Zn2+(out).","definition_xrefs":["RHEA:20621"],"direct_ancestors":[{"relation_name":"is_a","term_name":"zinc ion transmembrane transporter activity","termid":"GO:0005385"},{"relation_name":"is_a","term_name":"P-type ion transporter activity","termid":"GO:0015662"},{"relation_name":"is_a","term_name":"ATPase-coupled monoatomic cation transmembrane transporter activity","termid":"GO:0019829"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"P-type zinc transporter activity","secondary_identifiers":["EC:7.2.2.12","MetaCyc:RXN0-5205"],"synonyms":[{"name":"ATP phosphohydrolase (Zn2+-exporting)","type":"exact"},{"name":"P(1B)-type ATPase activity","type":"narrow"},{"name":"P1B-type ATPase activity","type":"related"},{"name":"Zn(2+)-exporting ATPase activity","type":"related"},{"name":"Zn2+-exporting ATPase activity","type":"related"},{"name":"zinc exporting ATPase activity","type":"broad"},{"name":"zinc transmembrane transporter activity, phosphorylative mechanism","type":"related"},{"name":"zinc-exporting ATPase activity","type":"related"},{"name":"zinc-translocating P-type ATPase activity","type":"exact"}],"termid":"GO:0016463"}


id: MONDO:0013850
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete periodic fever, menstrual cycle-dependent (obsolete MONDO:0013850)","termid":"MONDO:0013850","xrefs":{"Monarch":{"xref_id":"0013850"}}}


id: PBO:0073290
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"septin 14 pseudogene 12","termid":"PBO:0073290"}


id: PBO:0062516
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 8 subfamily K member 2 pseudogene","termid":"PBO:0062516"}


id: GO:0061327
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.","definition_xrefs":["GOC:dph","GOC:mtg_kidney_jan10","PMID:19783135"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Malpighian tubule development","termid":"GO:0072002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"anterior Malpighian tubule development","termid":"GO:0061327"}


id: PR:Q9HGM6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC543.05c gene.","definition_xrefs":["UniProtKB:Q9HGM6","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transporter C543.05c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC543.05c","synonyms":[{"name":"Spom972h-SPBC543.05c","type":"exact"}],"termid":"PR:Q9HGM6"}


id: PBO:0016976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Mug108","termid":"PBO:0016976"}


id: PBO:0084769
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial NAD+ transporter; involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs; YIA6 has a paralog, YEA6, that arose from the whole genome duplication; human NAD+ transporter MCART1/SLC25A51 functionally complements the yia6 yea6 double null mutant, and yeast YIA6 reciprocally complements defects in MCART1/SLC25A51 null cells","termid":"PBO:0084769"}


id: SO:0000602
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A short 3'-uridylated RNA that can form a duplex (except for its post-transcriptionally added oligo_U tail (SO:0000609)) with a stretch of mature edited mRNA.","direct_ancestors":[{"relation_name":"is_a","term_name":"ncRNA","termid":"SO:0000655"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guide_RNA","secondary_identifiers":["http://en.wikipedia.org/wiki/Guide_RNA"],"synonyms":[{"name":"INSDC_feature:ncRNA","type":"broad"},{"name":"INSDC_qualifier:guide_RNA","type":"exact"},{"name":"gRNA","type":"exact"},{"name":"guide RNA","type":"exact"}],"termid":"SO:0000602"}


id: PBO:0054745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2154","termid":"PBO:0054745"}


id: PBO:0067175
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 231, pseudogene","termid":"PBO:0067175"}


id: PBO:0070075
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6atac small nuclear 32, pseudogene","termid":"PBO:0070075"}


id: PBO:0061369
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleophosmin 1 pseudogene 29","termid":"PBO:0061369"}


id: GO:0098789
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.","gene_count":0,"genotype_count":0,"name":"obsolete pre-mRNA cleavage required for polyadenylation (obsolete GO:0098789)","synonyms":[{"name":"cleavage and polyadenylylation specificity factor activity","type":"related"},{"name":"pre-mRNA cleavage factor activity","type":"exact"}],"termid":"GO:0098789"}


id: PBO:0078238
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor beta variable 20-1","termid":"PBO:0078238"}


id: PBO:0039531
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 34B","termid":"PBO:0039531"}


id: PBO:0041078
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BRIX1 pseudogene 1","termid":"PBO:0041078"}


id: PBO:0090360
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UbiE family methyltransferase","termid":"PBO:0090360"}


id: PBO:0053467
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 430","termid":"PBO:0053467"}


id: MONDO:0003304
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An elongated and multinodular neurofibroma, formed when the tumor involves either multiple trunks of a plexus or multiple fascicles of a large nerve, such as the sciatic. Some plexiform neurofibromas resemble a bag of worms, others produce a massive ropy enlargement of the nerve. (Adapted from WHO.)","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurofibroma","termid":"MONDO:0016755"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plexiform neurofibroma","secondary_identifiers":["ICDO:9550/0","HP:0009732","ICD9:215.9","MESH:D018318","NCIT:C3797","UMLS:C0206728","SCTID:403818001","MEDGEN:64640","DOID:5151"],"synonyms":[{"name":"plexiform neurofibroma","type":"exact"},{"name":"plexiform neurofibroma (disease)","type":"exact"}],"termid":"MONDO:0003304","xrefs":{"Monarch":{"xref_id":"0003304"}}}


id: MONDO:0002273
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited metabolic disorder that involves plasma protein metabolism malfunction.","definition_xrefs":["DOID:2345"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn errors of metabolism","termid":"MONDO:0019052"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"plasma protein metabolism disease","secondary_identifiers":["MEDGEN:840208","ICD9:273.8","UMLS:C3875058"],"termid":"MONDO:0002273","xrefs":{"Monarch":{"xref_id":"0002273"}}}


id: SO:0000507
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A non functional descendant of an exon, part of a pseudogene.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pseudogenic_region","termid":"SO:0000462"},{"relation_name":"non_functional_homolog_of","term_name":"exon","termid":"SO:0000147"},{"relation_name":"part_of","term_name":"pseudogenic_transcript","termid":"SO:0000516"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pseudogenic_exon","synonyms":[{"name":"pseudogenic exon","type":"exact"}],"termid":"SO:0000507"}


id: PBO:0054204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1584","termid":"PBO:0054204"}


id: MOD:01186
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-threonine residue to either N-acetyl-L-threonne, or O-acetyl-Lthreonine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetylated residue","termid":"MOD:00394"},{"relation_name":"is_a","term_name":"modified L-threonine residue","termid":"MOD:00917"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acetylated L-threonine","synonyms":[{"name":"AcThr","type":"exact"}],"termid":"MOD:01186"}


id: GO:0061714
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.","definition_xrefs":["GOC:BHF","GOC:hal"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cargo receptor activity","termid":"GO:0038024"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038024"}],"interesting_parent_ids":["GO:0038024","GO:0003674"],"is_obsolete":false,"name":"folic acid receptor activity","synonyms":[{"name":"folate receptor activity","type":"exact"}],"termid":"GO:0061714"}


id: GO:0050163
data:
  {"annotated_genes":["SJAG_00493"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[107098],"is_not":false,"summary":null,"term":"GO:0050163"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.","definition_xrefs":["EC:5.3.2.2","RHEA:16021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, interconverting keto- and enol-groups","termid":"GO:0016862"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00493":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016853","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"oxaloacetate tautomerase activity","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["KEGG_REACTION:R00363","MetaCyc:OXALOACETATE-TAUTOMERASE-RXN"],"synonyms":[{"name":"oxalacetic keto-enol isomerase activity","type":"related"},{"name":"oxaloacetate keto-enol tautomerase activity","type":"related"},{"name":"oxaloacetate keto-enol-isomerase activity","type":"related"}],"termid":"GO:0050163","terms_by_termid":{"GO:0050163":null}}


id: GO:0072266
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal capsule formation","termid":"GO:0072129"},{"relation_name":"part_of","term_name":"metanephric capsule morphogenesis","termid":"GO:0072265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric capsule formation","termid":"GO:0072266"}


id: SO:0002291
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A non-coding RNA that is generated by backsplicing of exons or introns, resulting in a covalently closed loop without a 5’ cap or 3’ polyA tail.","definition_xrefs":["PMID:29626935","PMID:29230098","PMID:29086764","PMID:29182528","PMID:29576969"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ncRNA","termid":"SO:0000655"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"circular_ncRNA","synonyms":[{"name":"circRNA","type":"broad"},{"name":"circular ncRNA","type":"exact"},{"name":"noncoding circRNA","type":"exact"}],"termid":"SO:0002291"}


id: PBO:0054569
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1971","termid":"PBO:0054569"}


id: GO:0102552
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier].","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete lipoyl synthase activity (acting on glycine-cleavage complex H protein (obsolete GO:0102552)","termid":"GO:0102552"}


id: PBO:0086396
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative cytoplasmic short-chain dehydrogenase/reductase","termid":"PBO:0086396"}


id: MONDO:0015209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A gastroduodenal malformation that is not part of a larger syndrome.","definition_xrefs":["MONDO:patterns/isolated"],"gene_count":0,"genotype_count":0,"name":"obsolete non-syndromic gastroduodenal malformation (obsolete MONDO:0015209)","secondary_identifiers":["Orphanet:108963"],"synonyms":[{"name":"isolated gastroduodenal malformation","type":"exact"},{"name":"nonsyndromic gastroduodenal malformation","type":"exact"}],"termid":"MONDO:0015209","xrefs":{"Monarch":{"xref_id":"0015209"}}}


id: internal:pombase_gene_id
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pombase_gene_id","termid":"internal:pombase_gene_id"}


id: PBO:0025522
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by X. laevis MO15","termid":"PBO:0025522"}


id: PBO:0069235
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 490, pseudogene","termid":"PBO:0069235"}


id: GO:0097344
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes.","definition_xrefs":["GOC:vw","PMID:15260980","PMID:21385875","PMID:14759368"],"gene_count":0,"genotype_count":0,"name":"obsolete Rix1 complex (obsolete GO:0097344)","synonyms":[{"name":"IPI complex","type":"exact"}],"termid":"GO:0097344"}


id: PBO:0057305
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 515-2","termid":"PBO:0057305"}


id: GO:0043053
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development.","definition_xrefs":["PMID:10077613","GOC:cab1","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"entry into diapause","termid":"GO:0055115"},{"relation_name":"part_of","term_name":"dauer larval development","termid":"GO:0040024"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dauer entry","synonyms":[{"name":"nematode entry into dormancy","type":"exact"}],"termid":"GO:0043053"}


id: FYPO:0006078
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from ribosomal RNA are present at greater levels than normal.","definition_xrefs":["PMID:28541282","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased siRNA level","termid":"FYPO:0004207"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0001320","FYPO:0006551"],"is_obsolete":false,"name":"increased ribosomal RNA-derived siRNA level","synonyms":[{"name":"increased accumulation of ribosomal RNA-derived siRNA","type":"exact"},{"name":"increased accumulation of siRNAs homologous to ribosomal RNA","type":"related"},{"name":"increased level of ribosomal RNA-derived siRNA","type":"exact"},{"name":"increased level of siRNAs homologous to rRNA","type":"related"},{"name":"increased rRNA-derived siRNA level","type":"exact"},{"name":"increased ribosomal RNA-derived siRNA level during mitotic cell cycle","type":"related"},{"name":"increased ribosomal RNA-derived siRNA level during vegetative growth","type":"exact"}],"termid":"FYPO:0006078"}


id: PBO:0055321
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2749","termid":"PBO:0055321"}


id: GO:1900405
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cell separation after cytokinesis.","definition_xrefs":["PMID:10491317","PMID:12665550","GOC:mah","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter (obsolete GO:1900405)","synonyms":[{"name":"regulation of cytokinetic cell separation by regulation of transcription from RNA polymerase II promoter","type":"related"}],"termid":"GO:1900405"}


id: PR:O74360
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rga4 gene.","definition_xrefs":["UniProtKB:O74360","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rho-type GTPase-activating protein 4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC28E12.03","synonyms":[{"name":"Spom972h-rga4","type":"exact"}],"termid":"PR:O74360"}


id: PBO:0088162
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28","termid":"PBO:0088162"}


id: PATO:0000975
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000975 absolute porosity (obsolete PATO:0000975)","termid":"PATO:0000975"}


id: PBO:0087736
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the SMC5-SMC6 complex; the SMC5-SMC6 complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; binds single-stranded DNA and has ATPase activity; supports nucleolar function; S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair","termid":"PBO:0087736"}


id: PBO:0055790
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lysyl oxidase like 1","termid":"PBO:0055790"}


id: MOD:01631
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively removes or replaces an L-alanine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-alanine residue","termid":"MOD:00901"},{"relation_name":"is_a","term_name":"natural, standard, encoded residue removal","termid":"MOD:01651"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-alanine removal","termid":"MOD:01631"}


id: PATO:0000435
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000435 pattern value (obsolete PATO:0000435)","termid":"PATO:0000435"}


id: MONDO:0013400
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare, genetic, developmental defect during embryogenesis disorder characterized by severe, early-onset, salt-wasting adrenal insufficiency and ambiguous/female external genitalia (irrespective of chromosomal sex) due to mutations in the <i>CYP11A1</i> gene. Milder cases may present delayed onset of adrenal gland dysfunction and genitalia phenotype may range from normal male to female in individuals with 46,XY karyotype. Imaging studies reveal hypoplastic/absent adrenal glands and biochemical findings include low serum cortisol, mineralocorticoids, androgens, and sodium, with elevated potassium levels.","definition_xrefs":["Orphanet:168558"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"chronic primary adrenal insufficiency","termid":"MONDO:0015129"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"adrenal gland disorder","termid":"MONDO:0005495"},{"relation_name":"is_a","term_name":"46,XY disorder of sex development","termid":"MONDO:0020040"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Congenital adrenal insufficiency with 46, XY sex reversal OR 46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency","secondary_identifiers":["MESH:C566130","OMIM:613743","UMLS:C3151055","DOID:0050546","GARD:17033","NCIT:C131422","MEDGEN:462405"],"synonyms":[{"name":"46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency","type":"related"},{"name":"46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency syndrome","type":"related"},{"name":"XY sex reversal-adrenal failure","type":"exact"},{"name":"XY sex reversal-adrenal failure syndrome","type":"exact"},{"name":"adrenal insufficiency, congenital, with 46,XY SEX reversal, partial or complete","type":"exact"},{"name":"adrenal insufficiency, congenital, with 46XY sex reversal, partial or complete","type":"exact"},{"name":"cholesterol side-chain cleavage deficiency","type":"exact"},{"name":"p450scc deficiency","type":"exact"}],"termid":"MONDO:0013400","xrefs":{"Monarch":{"xref_id":"0013400"}}}


id: PBO:0087065
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L31B; associates with karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality; homologous to mammalian ribosomal protein L31, no bacterial homolog; RPL31B has a paralog, RPL31A, that arose from the whole genome duplication","termid":"PBO:0087065"}


id: MONDO:0034082
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete necrobiosis lipoidica (obsolete MONDO:0034082)","termid":"MONDO:0034082","xrefs":{"Monarch":{"xref_id":"0034082"}}}


id: GO:0052576
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.","definition_xrefs":["PMID:10758476"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate localization","termid":"GO:0052575"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"carbohydrate storage","termid":"GO:0052576"}


id: GO:0002156
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of thyroid hormone receptor signaling pathway","termid":"GO:0002155"},{"relation_name":"is_a","term_name":"negative regulation of intracellular signal transduction","termid":"GO:1902532"},{"relation_name":"negatively_regulates","term_name":"thyroid hormone receptor signaling pathway","termid":"GO:0002154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of thyroid hormone receptor signaling pathway","synonyms":[{"name":"negative regulation of thyroid hormone mediated signaling pathway","type":"exact"},{"name":"negative regulation of thyroid hormone mediated signalling pathway","type":"exact"}],"termid":"GO:0002156"}


id: MONDO:0800496
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A variable-age onset focal epilepsy syndrome with characteristic focal aware sensory auditory seizures. Seizures often produce such mild symptoms that they are not diagnosed. There are no implications expected for development or learning and seizures are typically infrequent and well controlled. EAF may occur as a familial syndrome, familial EAF (FEAF, previous known as autosomal dominant lateral temporal lobe epilepsy or autosomal dominant partial epilepsy with auditory features). Inheritance may be autosomal dominant (ADEAF), with incomplete penetrance.","direct_ancestors":[{"relation_name":"is_a","term_name":"variable-age onset focal epilepsy syndrome","termid":"MONDO:0800492"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"epilepsy with auditory features","synonyms":[{"name":"EAF","type":"exact"}],"termid":"MONDO:0800496","xrefs":{"Monarch":{"xref_id":"0800496"}}}


id: MONDO:0017439
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic amelia","termid":"MONDO:0017419"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"tetra-amelia","secondary_identifiers":["HP:0003057","Orphanet:294971","SCTID:702313004","UMLS:C2931216","GARD:5148","MESH:C536498","MEDGEN:444004"],"synonyms":[{"name":"Tetraamelia, autosomal recessive","type":"related"},{"name":"tetra-amelia syndrome","type":"related"},{"name":"tetra-amelia, autosomal recessive","type":"related"},{"name":"total amelia","type":"exact"}],"termid":"MONDO:0017439","xrefs":{"Monarch":{"xref_id":"0017439"}}}


id: PBO:0109403
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed transcript, Y-linked 30, pseudogene","termid":"PBO:0109403"}


id: GO:0103060
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose = kaempferol-3-rhamnoside-7-rhamnoside + UDP.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity (obsolete GO:0103060)","termid":"GO:0103060"}


id: MONDO:0009630
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"microphthalmia, isolated, with coloboma","termid":"MONDO:0000170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"microphthalmia, isolated, with coloboma 4","secondary_identifiers":["GARD:15200","MESH:C565378","SCTID:715771008","MEDGEN:344410","OMIM:251505","UMLS:C1855053"],"synonyms":[{"name":"MCOPCB4","type":"related"},{"name":"microphthalmia with colobomatous cyst","type":"related"},{"name":"microphthalmia, isolated, with coloboma 4","type":"exact"},{"name":"microphthalmia, isolated, with coloboma type 4","type":"exact"}],"termid":"MONDO:0009630","xrefs":{"Monarch":{"xref_id":"0009630"}}}


id: MONDO:0016764
data:
  {"annotated_genes":["SJAG_03786","SJAG_03497"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85464],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014050"},{"annotations":[87029],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013783"}]},"cv_name":"mondo","definition":"Anophthalmia and microphthalmia describe, respectively, the absence of an eye and the presence of a small eye within the orbit.","definition_xrefs":["Orphanet:2542"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete non-syndromic developmental defect of the eye (obsolete MONDO:0015217)","termid":"MONDO:0015217"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03497":null,"SJAG_03786":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"isolated anophthalmia-microphthalmia syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1826144","GARD:12085","UMLS:C5679828"],"synonyms":[{"name":"MAC spectrum","type":"exact"},{"name":"clinical anophthalmia","type":"related"},{"name":"isolated anophthalmia - microphthalmia","type":"related"},{"name":"isolated pure microphthalmia","type":"related"},{"name":"microphthalmia-anophthalmia-coloboma spectrum","type":"exact"},{"name":"nonsyndromic anophthalmia-microphthalmia syndrome","type":"exact"},{"name":"primitive anophthalmia","type":"related"}],"termid":"MONDO:0016764","terms_by_termid":{"MONDO:0013783":null,"MONDO:0014050":null},"xrefs":{"Monarch":{"xref_id":"0016764"}}}


id: FYPO:0001199
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal level of substance in cell during vegetative growth","termid":"FYPO:0001316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001312","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal cellular calcium level","synonyms":[{"name":"normal cellular calcium accumulation","type":"related"},{"name":"normal cellular calcium ion level","type":"exact"},{"name":"normal cellular calcium level during mitotic cell cycle","type":"related"},{"name":"normal cellular calcium level during vegetative growth","type":"exact"}],"termid":"FYPO:0001199"}


id: MONDO:0800206
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"epidermolysis bullosa dystrophica","termid":"MONDO:0006543"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"epidermolysis bullosa dystrophica with subcorneal cleavage","secondary_identifiers":["UMLS:C2675683","MEDGEN:436495"],"synonyms":[{"name":"EBDSC","type":"exact"}],"termid":"MONDO:0800206","xrefs":{"Monarch":{"xref_id":"0800206"}}}


id: GO:1990784
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.","definition_xrefs":["PMID:10051633"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to dsDNA","synonyms":[{"name":"response to double-stranded DNA","type":"exact"}],"termid":"GO:1990784"}


id: SO:0000928
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An edit to insert a AA dinucleotide.","definition_xrefs":["SO:ke"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:0000928 insert_AA (obsolete SO:0000928)","synonyms":[{"name":"insert AA","type":"exact"}],"termid":"SO:0000928"}


id: MONDO:0011997
data:
  {"annotated_genes":["SJAG_02453"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86333],"is_not":false,"summary":null,"term":"MONDO:0011997"}]},"cv_name":"mondo","definition":"A type of Hermansky-Pudlak syndrome (HPS), a multi-system disorder characterized by oculocutaneous albinism, bleeding diathesis and neutropenia.","definition_xrefs":["Orphanet:183678"],"direct_ancestors":[{"relation_name":"is_a","term_name":"constitutional neutropenia","termid":"MONDO:0015134"},{"relation_name":"is_a","term_name":"hereditary hemophagocytic lymphohistiocytosis","termid":"MONDO:0015541"},{"relation_name":"is_a","term_name":"Hermansky-Pudlak syndrome","termid":"MONDO:0019312"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02453":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005066","MONDO:0005093","MONDO:0005570"],"is_obsolete":false,"name":"Hermansky-Pudlak syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1842362","DOID:0060540","ICD10CM:E70.3","NCIT:C150368","MEDGEN:374912","GARD:15026","MESH:C537709","Orphanet:664500","NANDO:2200733","OMIM:608233"],"synonyms":[{"name":"AP3B1 Hermansky-Pudlak syndrome","type":"exact"},{"name":"HPS-2","type":"exact"},{"name":"HPS2","type":"exact"},{"name":"Hermansky Pudlak syndrome 2","type":"related"},{"name":"Hermansky-Pudlak syndrome 2","type":"exact"},{"name":"Hermansky-Pudlak syndrome caused by mutation in AP3B1","type":"exact"},{"name":"Hermansky-Pudlak syndrome type 2","type":"exact"},{"name":"Hermansky-Pudlak syndrome with neutropenia","type":"related"},{"name":"Platelet defects and oculocutaneous albinism","type":"related"}],"termid":"MONDO:0011997","terms_by_termid":{"MONDO:0011997":null},"xrefs":{"Monarch":{"xref_id":"0011997"}}}


id: PBO:0000978
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calmodulin Cam1","termid":"PBO:0000978"}


id: PBO:0050476
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"homeobox A4","termid":"PBO:0050476"}


id: GO:0072562
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.","definition_xrefs":["PMID:16373184","GOC:mah","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"extracellular space","termid":"GO:0005615"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005576"}],"interesting_parent_ids":["GO:0005575","GO:0005576"],"is_obsolete":false,"name":"blood microparticle","synonyms":[{"name":"cell membrane microparticle","type":"exact"}],"termid":"GO:0072562"}


id: PBO:0054305
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1697","termid":"PBO:0054305"}


id: GO:0009838
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The controlled shedding of a body part.","definition_xrefs":["ISBN:0140514031"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process","termid":"GO:0032502"},{"relation_name":"part_of","term_name":"multicellular organism development","termid":"GO:0007275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"abscission","secondary_identifiers":["Wikipedia:Abscission"],"termid":"GO:0009838"}


id: PBO:0064850
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 1","termid":"PBO:0064850"}


id: GO:0170057
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H+.","definition_xrefs":["EC:6.5.1.8","PMID:21311021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA ligase activity","termid":"GO:0008452"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016874","GO:0003824","GO:0003674","GO:0140098"],"is_obsolete":false,"name":"RNA ligase (GTP) activity","synonyms":[{"name":"3'-phosphate/5'-hydroxy nucleic acid ligase activity","type":"exact"}],"termid":"GO:0170057"}


id: GO:0034785
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+.","definition_xrefs":["UM-BBD_reactionID:r1034"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"salicylate 5-hydroxylase activity","secondary_identifiers":["EC:1.14.13.172","MetaCyc:RXN-10446","RHEA:35307"],"termid":"GO:0034785"}


id: GO:0097487
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A membrane-bounded vesicle wholly contained within a multivesicular body.","definition_xrefs":["PMID:21183070","GOC:pde"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytoplasmic vesicle","termid":"GO:0031410"},{"relation_name":"part_of","term_name":"multivesicular body","termid":"GO:0005771"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"is_a","termid":"GO:0031410"},{"rel_name":"part_of","termid":"GO:0005768"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0031410","GO:0005737","GO:0005575","GO:0005768"],"is_obsolete":false,"name":"multivesicular body, internal vesicle","termid":"GO:0097487"}


id: PR:Q10168
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A nuclear pore glycoprotein p62 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR12084:SF0","PRO:DNx","OMA:SCHPO01401"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleoporin nsp1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC26A3.15c","secondary_identifiers":["UniProtKB:Q10168"],"synonyms":[{"name":"Spom972h-NUP62","type":"exact"},{"name":"nuclear pore protein nsp1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"nucleoskeletal-like protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10168"}


id: PBO:0054004
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1332","termid":"PBO:0054004"}


id: PBO:0000089
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S. pombe specific DUF999 family protein 3","termid":"PBO:0000089"}


id: GO:0002687
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of leukocyte migration.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of immune system process","termid":"GO:0002684"},{"relation_name":"is_a","term_name":"regulation of leukocyte migration","termid":"GO:0002685"},{"relation_name":"is_a","term_name":"positive regulation of cell migration","termid":"GO:0030335"},{"relation_name":"positively_regulates","term_name":"leukocyte migration","termid":"GO:0050900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of leukocyte migration","synonyms":[{"name":"activation of leukocyte migration","type":"narrow"},{"name":"positive regulation of immune cell migration","type":"exact"},{"name":"positive regulation of leucocyte migration","type":"exact"},{"name":"stimulation of leukocyte migration","type":"narrow"},{"name":"up regulation of leukocyte migration","type":"exact"},{"name":"up-regulation of leukocyte migration","type":"exact"},{"name":"upregulation of leukocyte migration","type":"exact"}],"termid":"GO:0002687"}


id: PBO:0035756
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein-protein_interaction_during_cellular_response_to_salt_stress","termid":"PBO:0035756"}


id: GO:0018193
data:
  {"annotated_genes":["SJAG_00604","SJAG_02082","SJAG_01776","SJAG_02467","SJAG_00251","SJAG_02503","SJAG_04085","SJAG_04544","SJAG_05032","SJAG_03843","SJAG_01418","SJAG_04846","SJAG_00235","SJAG_01058","SJAG_01164","SJAG_00727"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[77342,78106,67024,59408,79433,80612,119077,59899],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017183"},{"annotations":[105556],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009249"},{"annotations":[98082,72838,114952,72728,75796,75950,76184],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016925"}]},"cv_name":"biological_process","definition":"The alteration of an amino acid residue in a peptide.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification process","termid":"GO:0036211"}],"gene_count":16,"genes_by_uniquename":{"SJAG_00235":null,"SJAG_00251":null,"SJAG_00604":null,"SJAG_00727":null,"SJAG_01058":null,"SJAG_01164":null,"SJAG_01418":null,"SJAG_01776":null,"SJAG_02082":null,"SJAG_02467":null,"SJAG_02503":null,"SJAG_03843":null,"SJAG_04085":null,"SJAG_04544":null,"SJAG_04846":null,"SJAG_05032":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-amino acid modification","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"termid":"GO:0018193","terms_by_termid":{"GO:0009249":null,"GO:0016925":null,"GO:0017183":null}}


id: PBO:0088447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein kinase (CK1 family) Cki1","termid":"PBO:0088447"}


id: FYPO:0005308
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone acetylation during vegetative growth","termid":"FYPO:0000332"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0002274","FYPO:0001320","FYPO:0001985","FYPO:0002494"],"is_obsolete":false,"name":"increased histone H4-K8 acetylation during vegetative growth","synonyms":[{"name":"increased histone H4-K8 acetylation during mitotic cell cycle","type":"related"},{"name":"increased histone H4K8 acetylation during vegetative growth","type":"exact"}],"termid":"FYPO:0005308"}


id: PBO:0040282
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase Na+/K+ transporting subunit alpha 2","termid":"PBO:0040282"}


id: PBO:0066750
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 48","termid":"PBO:0066750"}


id: MONDO:0017602
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"ALK-positive anaplastic large cell lymphoma (ALK+ ALCL) is a type of ALCL, a rare and aggressive peripheral T-cell non-Hodgkin lymphoma affecting lymph nodes and extranodal sites, which is characterized by the expression of a protein called anaplastic lymphoma kinase (ALK).","definition_xrefs":["Orphanet:300895"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anaplastic large cell lymphoma","termid":"MONDO:0020325"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"ALK-positive anaplastic large cell lymphoma","secondary_identifiers":["MEDGEN:233117","NCIT:C37193","UMLS:C1332079","GARD:21251","ICDO:9714/3"],"synonyms":[{"name":"ALCL, ALK+","type":"exact"},{"name":"ALK+ ALCL","type":"exact"},{"name":"ALK+ anaplastic large cell lymphoma","type":"exact"},{"name":"ALK-positive anaplastic large cell lymphoma","type":"exact"},{"name":"ALKoma","type":"exact"},{"name":"anaplastic large cell lymphoma, ALK-positive","type":"exact"}],"termid":"MONDO:0017602","xrefs":{"Monarch":{"xref_id":"0017602"}}}


id: GO:0002757
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals generated by a ligand binding to its receptor that lead to the activation or perpetuation of an immune response.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"activation of immune response","termid":"GO:0002253"},{"relation_name":"is_a","term_name":"immune response-regulating signaling pathway","termid":"GO:0002764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"immune response-activating signaling pathway","synonyms":[{"name":"immune response-activating signal transduction","type":"exact"}],"termid":"GO:0002757"}


id: GO:0010720
data:
  {"annotated_genes":["SJAG_00514","SJAG_02392","SJAG_04853","SJAG_02169","SJAG_03581"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[96180,90205,94916],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051519"},{"annotations":[102605],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0075296"},{"annotations":[91068],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903024"}]},"cv_name":"biological_process","definition":"Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.","definition_xrefs":["GOC:dph","GOC:BHF","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell differentiation","termid":"GO:0045597"},{"relation_name":"is_a","term_name":"regulation of cell development","termid":"GO:0060284"},{"relation_name":"positively_regulates","term_name":"cell development","termid":"GO:0048468"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00514":null,"SJAG_02169":null,"SJAG_02392":null,"SJAG_03581":null,"SJAG_04853":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of cell development","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0010720","terms_by_termid":{"GO:0051519":null,"GO:0075296":null,"GO:1903024":null}}


id: GO:0039568
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus.","definition_xrefs":["PMID:17287281"],"gene_count":0,"genotype_count":0,"name":"obsolete suppression by virus of host STAT1 activity by inhibition of DNA binding (obsolete GO:0039568)","synonyms":[{"name":"inhibition of DNA binding of STAT1","type":"exact"},{"name":"suppression by virus of host STAT1 activity by negative regulation of DNA binding","type":"exact"}],"termid":"GO:0039568"}


id: PBO:0079640
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBE2Q2 pseudogene 11","termid":"PBO:0079640"}


id: FYPO:0000977
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to silver ions is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular response to chemical stimulus during vegetative growth","termid":"FYPO:0001318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0000298","FYPO:0001312","FYPO:0001320"],"is_obsolete":false,"name":"normal cellular response to silver ion","synonyms":[{"name":"normal cellular response to silver ion during mitotic cell cycle","type":"related"},{"name":"normal cellular response to silver ion during vegetative growth","type":"exact"}],"termid":"FYPO:0000977"}


id: PBO:0004043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S ribosomal protein L35a (predicted)","termid":"PBO:0004043"}


id: PR:Q9UR17
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- nrf1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UR17"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar transporter chaperone 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC21B10.04c","synonyms":[{"name":"Spom972h-nrf1","type":"exact"},{"name":"negative regulator of cdc42 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UR17"}


id: MONDO:0018934
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete mucopolysaccharidosis type 1 (obsolete MONDO:0018934)","termid":"MONDO:0018934","xrefs":{"Monarch":{"xref_id":"0018934"}}}


id: MONDO:0007273
data:
  {"annotated_genes":["SJAG_00260"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85986],"is_not":false,"summary":null,"term":"MONDO:0007273"}]},"cv_name":"mondo","definition":"Any paraganglioma in which the cause of the disease is a mutation in the SDHB gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"paraganglioma","termid":"MONDO:0000448"},{"relation_name":"is_a","term_name":"central nervous system cancer","termid":"MONDO:0002714"},{"relation_name":"is_a","term_name":"adrenal gland cancer","termid":"MONDO:0002817"},{"relation_name":"is_a","term_name":"malignant urinary system neoplasm","termid":"MONDO:0006295"},{"relation_name":"is_a","term_name":"hereditary pheochromocytoma-paraganglioma","termid":"MONDO:0017366"},{"relation_name":"is_a","term_name":"peripheral nervous system cancer","termid":"MONDO:0021089"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00260":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"paragangliomas 4","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:349380","UMLS:C1861848","GARD:10546","OMIM:115310"],"synonyms":[{"name":"PGL4","type":"related"},{"name":"SDHB paraganglioma","type":"exact"},{"name":"SDHB-related hereditary paraganglioma-pheochromocytoma syndrome","type":"related"},{"name":"carotid body tumors and multiple extraadrenal Pheochromocytomas","type":"related"},{"name":"carotid body tumours and multiple extraadrenal Pheochromocytomas","type":"related"},{"name":"paraganglioma caused by mutation in SDHB","type":"exact"},{"name":"paraganglioma, familial malignant","type":"related"},{"name":"paragangliomas 4","type":"exact"},{"name":"paragangliomas type 4","type":"exact"},{"name":"paragangliomas, hereditary extraadrenal","type":"related"},{"name":"pheochromocytoma, extraadrenal and cervical paraganglioma","type":"related"},{"name":"pheochromocytoma, extraadrenal, and cervical paraganglioma","type":"related"},{"name":"pheochromocytoma, familial extraadrenal","type":"related"}],"termid":"MONDO:0007273","terms_by_termid":{"MONDO:0007273":null},"xrefs":{"Monarch":{"xref_id":"0007273"}}}


id: GO:0019501
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"arsonoacetate metabolic process","termid":"GO:0018872"},{"relation_name":"is_a","term_name":"xenobiotic catabolic process","termid":"GO:0042178"},{"relation_name":"is_a","term_name":"carboxylic acid catabolic process","termid":"GO:0046395"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"arsonoacetate catabolic process","secondary_identifiers":["MetaCyc:P482-PWY"],"synonyms":[{"name":"arsonoacetate breakdown","type":"exact"},{"name":"arsonoacetate catabolism","type":"exact"},{"name":"arsonoacetate degradation","type":"exact"}],"termid":"GO:0019501"}


id: GO:0071223
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to lipoteichoic acid","termid":"GO:0070391"},{"relation_name":"is_a","term_name":"cellular response to molecule of bacterial origin","termid":"GO:0071219"},{"relation_name":"is_a","term_name":"cellular response to oxygen-containing compound","termid":"GO:1901701"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to lipoteichoic acid","synonyms":[{"name":"cellular response to LTA","type":"exact"}],"termid":"GO:0071223"}


id: PBO:0060370
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotilin","termid":"PBO:0060370"}


id: MONDO:0023275
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cystic hamartoma of lung and kidney is a rare developmental malformation reported in 3 patients characterized by the presence of benign hamartomatous cysts in kidney and lung, clinically presenting as abdominal mass. Others associated features include hyperplastic nephromegaly, medullary dysplasia and mesoblastic nephroma. There have been no further descriptions in the literature since 1987.","definition_xrefs":["Orphanet:2111"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney cancer","termid":"MONDO:0002367"},{"relation_name":"is_a","term_name":"lung cancer","termid":"MONDO:0008903"},{"relation_name":"is_a","term_name":"hamartoma of lung","termid":"MONDO:0021540"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005240"],"is_obsolete":false,"name":"Graham-Boyle-Troxell syndrome","secondary_identifiers":["SCTID:707530009","MEDGEN:444062","UMLS:C2931468","MESH:C537292","GARD:2557","ICD9:759.6"],"synonyms":[{"name":"Graham-Boyle-Troxell syndrome","type":"exact"},{"name":"cystic hamartoma of lung and kidney","type":"exact"},{"name":"cystic hamartomata of lung and kidney","type":"related"},{"name":"graham Boyle Troxell syndrome","type":"exact"}],"termid":"MONDO:0023275","xrefs":{"Monarch":{"xref_id":"0023275"}}}


id: PBO:0071594
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L36a pseudogene 11","termid":"PBO:0071594"}


id: PBO:0059769
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO3 pseudogene 43","termid":"PBO:0059769"}


id: PBO:0048645
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gap junction protein beta 5","termid":"PBO:0048645"}


id: PBO:0047116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 163 member A","termid":"PBO:0047116"}


id: GO:2000539
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein geranylgeranylation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of macromolecule biosynthetic process","termid":"GO:0010556"},{"relation_name":"is_a","term_name":"regulation of protein modification process","termid":"GO:0031399"},{"relation_name":"regulates","term_name":"protein geranylgeranylation","termid":"GO:0018344"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of protein geranylgeranylation","synonyms":[{"name":"regulation of C-terminal protein geranylgeranylation","type":"related"},{"name":"regulation of protein amino acid geranylgeranylation","type":"exact"}],"termid":"GO:2000539"}


id: PBO:0074583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 2B","termid":"PBO:0074583"}


id: GO:0002194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes.","definition_xrefs":["CL:0000182","PMID:9794819"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell migration","termid":"GO:0016477"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hepatocyte cell migration","termid":"GO:0002194"}


id: GO:0046153
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catabolic process","termid":"GO:0009056"},{"relation_name":"is_a","term_name":"eye pigment catabolic process","termid":"GO:0046151"},{"relation_name":"is_a","term_name":"ommochrome metabolic process","termid":"GO:0046152"},{"relation_name":"is_a","term_name":"ocellus pigment catabolic process","termid":"GO:0046159"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"ommochrome catabolic process","synonyms":[{"name":"ommochrome breakdown","type":"exact"},{"name":"ommochrome catabolism","type":"exact"},{"name":"ommochrome degradation","type":"exact"}],"termid":"GO:0046153"}


id: PBO:0061516
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NSA2 pseudogene 6","termid":"PBO:0061516"}


id: GO:2000389
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of neutrophil extravasation.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular extravasation","termid":"GO:0002691"},{"relation_name":"is_a","term_name":"regulation of neutrophil migration","termid":"GO:1902622"},{"relation_name":"regulates","term_name":"neutrophil extravasation","termid":"GO:0072672"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of neutrophil extravasation","termid":"GO:2000389"}


id: PBO:0039686
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amyloid beta precursor protein binding family B member 3","termid":"PBO:0039686"}


id: PBO:0026666
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-multinucleate_multiseptate_cell","termid":"PBO:0026666"}


id: FYPO:0002031
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin cytoskeleton morphology during vegetative growth","termid":"FYPO:0000350"},{"relation_name":"is_a","term_name":"abnormal actin cables","termid":"FYPO:0002435"},{"relation_name":"output_of","term_name":"abnormal actin cable organization","termid":"FYPO:0002030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0004803"},{"rel_name":"output_of","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0001985","FYPO:0004803"],"is_obsolete":false,"name":"abnormal actin cable morphology","synonyms":[{"name":"abnormal actin cable morphology during mitotic cell cycle","type":"related"},{"name":"abnormal actin cable morphology during vegetative growth","type":"exact"},{"name":"abnormal formin-nucleated actin cable morphology","type":"exact"},{"name":"disorganized actin cables","type":"exact"}],"termid":"FYPO:0002031"}


id: PBO:0076836
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TERF1 pseudogene 3","termid":"PBO:0076836"}


id: MONDO:0021518
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the hard palate.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"palatal neoplasm","termid":"MONDO:0005286"},{"relation_name":"is_a","term_name":"benign neoplasm of oral cavity","termid":"MONDO:0021445"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign neoplasm of hard palate","secondary_identifiers":["ICD9:210.4","UMLS:C0345552","MEDGEN:138020","NCIT:C4403","SCTID:92129006"],"synonyms":[{"name":"benign hard palate neoplasm","type":"exact"},{"name":"benign hard palate tumor","type":"exact"},{"name":"benign hard palate tumour","type":"exact"},{"name":"benign neoplasm of the hard palate","type":"exact"},{"name":"benign tumor of hard palate","type":"exact"},{"name":"benign tumor of the hard palate","type":"exact"},{"name":"benign tumour of hard palate","type":"exact"},{"name":"benign tumour of the hard palate","type":"exact"},{"name":"hard palate benign neoplasm","type":"exact"}],"termid":"MONDO:0021518","xrefs":{"Monarch":{"xref_id":"0021518"}}}


id: FYPO:0000634
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization to centromere during vegetative growth","termid":"FYPO:0000449"},{"relation_name":"is_a","term_name":"abolished protein localization to chromosome during vegetative growth","termid":"FYPO:0002841"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000138","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"abolished protein localization to centromere during vegetative growth","synonyms":[{"name":"abolished protein localisation to centromere during vegetative growth","type":"exact"},{"name":"abolished protein localisation to chromosome, centromeric region during vegetative growth","type":"exact"},{"name":"abolished protein localization to centromere during mitotic cell cycle","type":"related"},{"name":"abolished protein localization to chromosome, centric region during vegetative growth","type":"exact"},{"name":"abolished protein localization to chromosome, centromeric region during vegetative growth","type":"exact"},{"name":"protein absent from centromere during vegetative growth","type":"related"},{"name":"protein localization to centromere abolished during vegetative growth","type":"exact"}],"termid":"FYPO:0000634"}


id: FYPO:0003886
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein.","definition_xrefs":["PomBase:mah","GO:0006897"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal transport","termid":"FYPO:0001720"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000002","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"abnormal endocytosis","synonyms":[{"name":"abnormal actin-mediated endocytosis","type":"exact"},{"name":"abnormal protein internalization","type":"narrow"},{"name":"endocytosis defects","type":"exact"},{"name":"endocytosis: abnormal","type":"related"}],"termid":"FYPO:0003886"}


id: MONDO:0019552
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Centrifugal lipodystrophy is a rare, acquired, localized lipodistrophy characterized by single or, occasionally, multiple, centrifugally progressive, asymptomatic to sometimes mildly tender, hypopigmented, lipoatrophic skin depressions with weakly erymatheous inflammatory borders, typically associated with regional ipsilateral lymph nodes swelling. Lesions typically occur on lower trunk (in particular groin and abdomen region), followed by upper trunk (axilla and neighboring regions) and, rarely, neck and head. It is usually not associated with systemic disease and is typically self-resolving.","definition_xrefs":["Orphanet:90156"],"direct_ancestors":[{"relation_name":"is_a","term_name":"localized lipodystrophy","termid":"MONDO:0019194"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005066"],"is_obsolete":false,"name":"centrifugal lipodystrophy","secondary_identifiers":["GARD:19125","MEDGEN:590539","UMLS:C0406605","icd11.foundation:1561732835"],"synonyms":[{"name":"lipodystrophia centrifugalis abdominalis infantilis","type":"exact"}],"termid":"MONDO:0019552","xrefs":{"Monarch":{"xref_id":"0019552"}}}


id: PBO:0046814
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coagulation factor XIII B chain","termid":"PBO:0046814"}


id: PBO:0108626
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ino80, NuA4 and Swr1 complex actin-like protein Arp4","termid":"PBO:0108626"}


id: GO:0034037
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.","definition_xrefs":["GOC:mah","GOC:pde"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribonucleoside bisphosphate catabolic process","termid":"GO:0034031"},{"relation_name":"is_a","term_name":"purine nucleoside bisphosphate catabolic process","termid":"GO:0034034"},{"relation_name":"is_a","term_name":"purine ribonucleoside bisphosphate metabolic process","termid":"GO:0034035"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0055086"],"is_obsolete":false,"name":"purine ribonucleoside bisphosphate catabolic process","synonyms":[{"name":"purine ribonucleoside bisphosphate breakdown","type":"exact"},{"name":"purine ribonucleoside bisphosphate catabolism","type":"exact"},{"name":"purine ribonucleoside bisphosphate degradation","type":"exact"}],"termid":"GO:0034037"}


id: PBO:0074520
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small NF90 (ILF3) associated RNA A12","termid":"PBO:0074520"}


id: MONDO:0700067
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any myopathy in which the cause of the disease is a variation in the FKTN gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myopathy","termid":"MONDO:0005336"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of protein involved in O-glycosylation of alpha-dystroglycan","termid":"MONDO:0016155"},{"relation_name":"is_a","term_name":"hereditary skeletal muscle disorder","termid":"MONDO:0700223"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0024322"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002320","MONDO:0024322","MONDO:0005336"],"is_obsolete":false,"name":"myopathy caused by variation in FKTN","synonyms":[{"name":"FKTN myopathy","type":"exact"},{"name":"FKTN-related myopathy","type":"exact"},{"name":"myopathy caused by mutation in FKTN","type":"exact"}],"termid":"MONDO:0700067","xrefs":{"Monarch":{"xref_id":"0700067"}}}


id: PBO:0051045
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy diversity 1-14 (non-functional)","termid":"PBO:0051045"}


id: PBO:0110160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA chaperone, La protein, Sla1","termid":"PBO:0110160"}


id: FYPO:0004406
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing JM335.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0000257","FYPO:0000003","FYPO:0002057","FYPO:0002058","FYPO:0002060"],"is_obsolete":false,"name":"normal growth on JM335","synonyms":[{"name":"normal cell population growth in presence of JM335","type":"exact"},{"name":"normal cell population growth on JM335","type":"exact"},{"name":"normal cellular response to JM335","type":"related"},{"name":"normal vegetative cell population growth on JM335","type":"exact"}],"termid":"FYPO:0004406"}


id: PBO:0076610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TBC1 domain family member 28","termid":"PBO:0076610"}


id: MONDO:0003274
data:
  {"annotated_genes":["SJAG_03453","SJAG_04206","SJAG_03720","SJAG_00229","SJAG_00079","SJAG_02426","SJAG_02460","SJAG_00757","SJAG_04394","SJAG_04114","SJAG_01410","SJAG_04502","SJAG_03689"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87673,86552,86551,87672,86549,87670,87669,87671,86550,86548],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0016419"},{"annotations":[87156,87157,87688],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008903"},{"annotations":[86702],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011014"}]},"cv_name":"mondo","definition":"A primary or metastatic malignant neoplasm affecting the tissues of the thorax.","definition_xrefs":["NCIT:C3576"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cancer","termid":"MONDO:0004992"},{"relation_name":"is_a","term_name":"neoplasm of thorax","termid":"MONDO:0021350"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00079":null,"SJAG_00229":null,"SJAG_00757":null,"SJAG_01410":null,"SJAG_02426":null,"SJAG_02460":null,"SJAG_03453":null,"SJAG_03689":null,"SJAG_03720":null,"SJAG_04114":null,"SJAG_04206":null,"SJAG_04394":null,"SJAG_04502":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"thoracic cancer","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:5093","ICD9:195.1","MEDGEN:56320","UMLS:C0153661","SCTID:188361007"],"synonyms":[{"name":"cancer of thoracic segment of trunk","type":"exact"},{"name":"malignant neoplasm of the thorax","type":"exact"},{"name":"malignant neoplasm of thoracic segment of trunk","type":"exact"},{"name":"malignant neoplasm of thorax","type":"exact"},{"name":"malignant thoracic neoplasm","type":"exact"},{"name":"malignant thoracic segment of trunk neoplasm","type":"exact"},{"name":"malignant thoracic tumor","type":"exact"},{"name":"malignant thoracic tumour","type":"exact"},{"name":"malignant tumor of the thorax","type":"exact"},{"name":"malignant tumor of thorax","type":"exact"},{"name":"malignant tumour of the thorax","type":"exact"},{"name":"malignant tumour of thorax","type":"exact"},{"name":"thoracic segment of trunk cancer","type":"exact"},{"name":"thoracic tumor","type":"broad"},{"name":"thoracic tumour","type":"broad"},{"name":"thorax cancer","type":"exact"},{"name":"thorax neoplasm","type":"broad"},{"name":"tumor of thorax","type":"broad"},{"name":"tumour of thorax","type":"broad"}],"termid":"MONDO:0003274","terms_by_termid":{"MONDO:0008903":null,"MONDO:0011014":null,"MONDO:0016419":null},"xrefs":{"Monarch":{"xref_id":"0003274"}}}


id: PBO:0084264
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Integral inner mitochondrial membrane protein; role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases","termid":"PBO:0084264"}


id: MONDO:0014714
data:
  {"annotated_genes":["SJAG_00279","SJAG_01943"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86358,86359],"is_not":false,"summary":null,"term":"MONDO:0014714"}]},"cv_name":"mondo","definition":"Progressive microcephaly-seizures-cortical blindness-developmental delay syndrome is a rare, genetic, neuro-ophthalmological syndrome characterized by post-natal, progressive microcephaly and early-onset seizures, associated with delayed global development, bilateral cortical visual impairment and moderate to severe intellectual disability. Additional manifestations include short stature, generalized hypotonia and pulmonary complications, such as recurrent respiratory infections and bronchiectasis. Auditory and metabolic screenings are normal.","definition_xrefs":["Orphanet:477814"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00279":null,"SJAG_01943":null},"genotype_count":0,"is_obsolete":false,"name":"progressive microcephaly-seizures-cortical blindness-developmental delay syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5567650","MEDGEN:1799073","GARD:17858","OMIM:616632"],"synonyms":[{"name":"SCBMS","type":"exact"},{"name":"seizures, cortical blindness, and microcephaly syndrome","type":"related"},{"name":"seizures, cortical blindness, microcephaly syndrome","type":"exact"}],"termid":"MONDO:0014714","terms_by_termid":{"MONDO:0014714":null},"xrefs":{"Monarch":{"xref_id":"0014714"}}}


id: PBO:0066192
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RBM12B antisense RNA 1","termid":"PBO:0066192"}


id: GO:0071835
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.","definition_xrefs":["GOC:mah","GOC:elh","GOC:jh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mating pheromone secretion","termid":"GO:0071834"},{"relation_name":"part_of","term_name":"conjugation with cellular fusion","termid":"GO:0000747"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"part_of","termid":"GO:0000747"},{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0000747","GO:0051179","GO:0023052","GO:0006810"],"is_obsolete":false,"name":"mating pheromone secretion involved in regulation of conjugation with cellular fusion","secondary_identifiers":["GO:0071832"],"synonyms":[{"name":"mating pheromone secretion involved in regulation of conjugation","type":"related"},{"name":"mating-type pheromone secretion involved in conjugation","type":"exact"},{"name":"peptide pheromone export involved in regulation of conjugation","type":"broad"}],"termid":"GO:0071835"}


id: PBO:0052620
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KRR1 small subunit processome component homolog","termid":"PBO:0052620"}


id: MONDO:0004778
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder involving inflammation of the epididymis and testes.","direct_ancestors":[{"relation_name":"is_a","term_name":"epididymitis","termid":"MONDO:0004779"},{"relation_name":"is_a","term_name":"orchitis","termid":"MONDO:0006882"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epididymo-orchitis","secondary_identifiers":["ICD9:604.90","MEDGEN:508448","icd11.foundation:1745517194","ICD9:604","ICD10CM:N45.3","DOID:9401","SCTID:197983000","UMLS:C0149881"],"termid":"MONDO:0004778","xrefs":{"Monarch":{"xref_id":"0004778"}}}


id: GO:0018905
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.","definition_xrefs":["UM-BBD_pathwayID:dme"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xenobiotic metabolic process","termid":"GO:0006805"},{"relation_name":"is_a","term_name":"ether metabolic process","termid":"GO:0018904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281"],"is_obsolete":false,"name":"dimethyl ether metabolic process","synonyms":[{"name":"dimethyl ether metabolism","type":"exact"},{"name":"methyl ether metabolic process","type":"exact"},{"name":"methyl ether metabolism","type":"exact"}],"termid":"GO:0018905"}


id: PBO:0045168
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DnaJ heat shock protein family (Hsp40) member A1 pseudogene 2","termid":"PBO:0045168"}


id: GO:0061860
data:
  {"annotated_genes":["SJAG_04150","SJAG_01010","SJAG_00272","SJAG_00729","SJAG_02182"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[89922,94311,95611,112587,113141],"is_not":false,"summary":null,"term":"GO:0061860"}]},"cv_name":"molecular_function","definition":"Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis.","definition_xrefs":["PMID:23499004","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ATP-dependent activity, acting on DNA","termid":"GO:0008094"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00272":null,"SJAG_00729":null,"SJAG_01010":null,"SJAG_02182":null,"SJAG_04150":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0140097","GO:0003674"],"is_obsolete":false,"name":"DNA clamp unloader activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"DNA clamp unloading activity","type":"exact"}],"termid":"GO:0061860","terms_by_termid":{"GO:0061860":null}}


id: MONDO:0005579
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A generalised epilepsy that encompasses several common seizure phenotypes including childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy and epilepsy with generalized tonic-clonic seizures alone. These epilepsy syndromes have polygenic inheritance with or without environmental factors contributing to seizure susceptibility. Seizure types include one or a combination of absence seizures, myoclonic seizures and/or generalized tonic-clonic seizures.","definition_xrefs":["OMIM:600669"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary generalized epilepsy","termid":"MONDO:0100576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"idiopathic generalized epilepsy","secondary_identifiers":["UMLS:C0270850","SCTID:19598007","MESH:C562694","EFO:0005917","DOID:1827","MEDGEN:75725","OMIMPS:600669"],"synonyms":[{"name":"EIG","type":"exact"},{"name":"IGE","type":"exact"},{"name":"epilepsy, idiopathic generalized","type":"exact"},{"name":"generalized epilepsy","type":"broad"},{"name":"hereditary idiopathic generalized epilepsy","type":"exact"},{"name":"idiopathic generalised epilepsy","type":"exact"},{"name":"idiopathic generalized epilepsy","type":"exact"}],"termid":"MONDO:0005579","xrefs":{"Monarch":{"xref_id":"0005579"}}}


id: PBO:0031292
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-localization_phenotype","termid":"PBO:0031292"}


id: PBO:0072192
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S17 pseudogene 9","termid":"PBO:0072192"}


id: SO:0000017
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A sequence element characteristic of the promoters of snRNA genes transcribed by RNA polymerase II or by RNA polymerase III. Located between -45 and -60 relative to the TSS. The human PSE_motif consensus sequence is TCACCNTNA(C|G)TNAAAAG(T|G). The basal transcription factor, snRNA-activating protein complex (SNAPc), binds the PSE_motif and is required for the transcription of both RNA polymerase II and III transcribed small-nuclear RNA genes.","definition_xrefs":["PMID:11390411","PMID:12621023","PMID:23166507","PMID:8339931","PMID:12651739"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA_motif","termid":"SO:0000713"},{"relation_name":"part_of","term_name":"promoter","termid":"SO:0000167"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PSE_motif","synonyms":[{"name":"PSE motif","type":"exact"},{"name":"proximal sequence element","type":"exact"}],"termid":"SO:0000017"}


id: PBO:0030310
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_level_in_germinating_spore","termid":"PBO:0030310"}


id: GO:0019432
data:
  {"annotated_genes":["SJAG_02763","SJAG_03609","SJAG_03162","SJAG_04041"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[71626,74908,77325,90376],"is_not":false,"summary":null,"term":"GO:0019432"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triglyceride metabolic process","termid":"GO:0006641"},{"relation_name":"is_a","term_name":"acylglycerol biosynthetic process","termid":"GO:0046463"}],"gene_count":4,"genes_by_uniquename":{"SJAG_02763":null,"SJAG_03162":null,"SJAG_03609":null,"SJAG_04041":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"triglyceride biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:TRIGLSYN-PWY","Reactome:R-HSA-75109"],"synonyms":[{"name":"triacylglycerol biosynthesis","type":"exact"},{"name":"triacylglycerol biosynthetic process","type":"exact"},{"name":"triglyceride anabolism","type":"exact"},{"name":"triglyceride biosynthesis","type":"exact"},{"name":"triglyceride formation","type":"exact"},{"name":"triglyceride synthesis","type":"exact"}],"termid":"GO:0019432","terms_by_termid":{"GO:0019432":null}}


id: MONDO:0024350
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"exanthem","termid":"MONDO:0006547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"pityriasis steatoides","secondary_identifiers":["UMLS:C1274781","ICD9:696.5","MEDGEN:698103","SCTID:403426003"],"synonyms":[{"name":"pityriasis steatoides","type":"exact"}],"termid":"MONDO:0024350","xrefs":{"Monarch":{"xref_id":"0024350"}}}


id: _global:formed_as_result_of
data:
  {"annotation_feature_type":"gene","cv_name":"external","direct_ancestors":[{"relation_name":"is_a","term_name":"output_of","termid":"_global:output_of"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"formed_as_result_of","secondary_identifiers":["RO:0002354"],"termid":"_global:formed_as_result_of"}


id: GO:1904126
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any convergent extension that is involved in notochord morphogenesis.","definition_xrefs":["GOC:dph","PMID:24892953","GOC:TermGenie","GO_REF:0000060"],"direct_ancestors":[{"relation_name":"is_a","term_name":"convergent extension involved in gastrulation","termid":"GO:0060027"},{"relation_name":"is_a","term_name":"convergent extension involved in organogenesis","termid":"GO:0060029"},{"relation_name":"part_of","term_name":"notochord morphogenesis","termid":"GO:0048570"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"convergent extension involved in notochord morphogenesis","termid":"GO:1904126"}


id: PBO:0108888
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPL7L1 pseudogene 1","termid":"PBO:0108888"}


id: MONDO:0014122
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any myofibromatosis in which the cause of the disease is a mutation in the NOTCH3 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"infantile myofibromatosis","termid":"MONDO:0016824"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myofibromatosis, infantile, 2","secondary_identifiers":["GARD:15939","MEDGEN:815414","NCIT:C176944","OMIM:615293","UMLS:C3809084"],"synonyms":[{"name":"IMF2","type":"related"},{"name":"NOTCH3 myofibromatosis","type":"exact"},{"name":"myofibromatosis caused by mutation in NOTCH3","type":"exact"},{"name":"myofibromatosis, infantile 2","type":"exact"},{"name":"myofibromatosis, infantile, 2","type":"exact"},{"name":"myofibromatosis, infantile, type 2","type":"exact"}],"termid":"MONDO:0014122","xrefs":{"Monarch":{"xref_id":"0014122"}}}


id: PBO:0086203
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that associates with mitochondrial ribosome; sumoylated under stress conditions in a genome wide study; YDR336W is not an essential gene","termid":"PBO:0086203"}


id: MOD:01208
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts a C-terminal residue to the copper(1+) carboxylate salt.","definition_xrefs":["Unimod:531#C-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"copper containing modified residue","termid":"MOD:00742"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"copper(1+) carboxylate C-terminal residue","synonyms":[{"name":"Cation:Cu[I]","type":"related"},{"name":"Replacement of proton by copper","type":"related"},{"name":"cuprous salt","type":"exact"}],"termid":"MOD:01208"}


id: PATO:0000879
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000879 fecundity value (obsolete PATO:0000879)","termid":"PATO:0000879"}


id: MONDO:0018426
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"attenuated familial adenomatous polyposis","termid":"MONDO:0016362"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AXIN2-related attenuated familial adenomatous polyposis","secondary_identifiers":["MEDGEN:1826067","Orphanet:401911","UMLS:C5680012","GARD:21703"],"synonyms":[{"name":"AXIN2-related AFAP","type":"exact"},{"name":"AXIN2-related attenuated FAP","type":"exact"},{"name":"AXIN2-related attenuated familial polyposis coli","type":"exact"}],"termid":"MONDO:0018426","xrefs":{"Monarch":{"xref_id":"0018426"}}}


id: GO:0009780
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions.","definition_xrefs":["ISBN:0716746840","GOC:jid","ISBN:0816017360"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NADPH regeneration","termid":"GO:0006740"},{"relation_name":"part_of","term_name":"photosynthesis, light reaction","termid":"GO:0019684"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0006091"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281","GO:0006091"],"is_obsolete":false,"name":"photosynthetic NADP+ reduction","termid":"GO:0009780"}


id: PBO:0044783
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"death effector domain containing","termid":"PBO:0044783"}


id: MONDO:0800442
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A heart disease that is present at birth that is caused by a variation in MYH-6. Representative examples include atrial septal defect, ventricular septal defect, tetralogy of Fallot and hypoplastic left heart syndrome.","definition_xrefs":["PMID:20656787","PMID:29505555","PMID:29969989","PMID:31638415","PMID:34481090","PMID:35863714","PMID:34384224","PMID:29590334","PMID:22194935","PMID:15735645"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital heart defects, multiple types","termid":"MONDO:0000119"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"MYH-6 related congenital heart defects","synonyms":[{"name":"MYH6 related congenital heart defects","type":"exact"}],"termid":"MONDO:0800442","xrefs":{"Monarch":{"xref_id":"0800442"}}}


id: MOD:00694
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes a halogen atom for a hydrogen atom.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by chemical process","termid":"MOD:01156"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"halogen containing residue","synonyms":[{"name":"HalRes","type":"exact"},{"name":"halogenated residue","type":"exact"}],"termid":"MOD:00694"}


id: PBO:0048353
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glyceraldehyde-3-phosphate dehydrogenase pseudogene 64","termid":"PBO:0048353"}


id: CHEBI:28304
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heparin","termid":"CHEBI:28304"}


id: MONDO:0019846
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acquired central diabetes insipidus (acquired CDI) is a subtype of central diabetes insipidus (CDI), characterized by polyuria and polydipsia, due to an idiopathic or secondary decrease in vasopressin (AVP) production.","definition_xrefs":["Orphanet:95626"],"direct_ancestors":[{"relation_name":"is_a","term_name":"central diabetes insipidus","termid":"MONDO:0015790"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acquired central diabetes insipidus","secondary_identifiers":["UMLS:C5680256","ICD10CM:E23.2","MEDGEN:1843437","icd11.foundation:1677009817","GARD:19291"],"synonyms":[{"name":"acquired CDI","type":"exact"},{"name":"acquired central diabetes insipidus","type":"exact"},{"name":"acquired neurogenic diabetes insipidus","type":"exact"}],"termid":"MONDO:0019846","xrefs":{"Monarch":{"xref_id":"0019846"}}}


id: PBO:0003449
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.1.1.71","termid":"PBO:0003449"}


id: GO:0050884
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuromuscular process","termid":"GO:0050905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neuromuscular process controlling posture","synonyms":[{"name":"regulation of posture","type":"exact"}],"termid":"GO:0050884"}


id: PR:Q9HE05
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A ubiquitin conjugation factor E4 B that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00878","PANTHER:PTHR13931:SF2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin conjugation factor E4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC20H4.10","secondary_identifiers":["UniProtKB:Q9HE05"],"synonyms":[{"name":"Spom972h-UBE4B","type":"exact"},{"name":"UB fusion protein 2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin fusion degradation protein 2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9HE05"}


id: PBO:0050272
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HMGN3 antisense RNA 1","termid":"PBO:0050272"}


id: MONDO:0015417
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"facial cleft","termid":"MONDO:0015411"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tessier number 6 facial cleft","secondary_identifiers":["UMLS:C0432120","icd11.foundation:1934815559","GARD:19969","Orphanet:141265","MEDGEN:609365"],"termid":"MONDO:0015417","xrefs":{"Monarch":{"xref_id":"0015417"}}}


id: MONDO:0011378
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete CFM1 (obsolete MONDO:0011378)","secondary_identifiers":["OMIM:603855"],"synonyms":[{"name":"CFM1","type":"exact"},{"name":"cystic fibrosis, modifier of, 1","type":"related"},{"name":"meconium ileus in cystic fibrosis, susceptibility to","type":"related"}],"termid":"MONDO:0011378","xrefs":{"Monarch":{"xref_id":"0011378"}}}


id: PATO:0000343
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000343 gametophyte incompatible value (obsolete PATO:0000343)","termid":"PATO:0000343"}


id: MONDO:0003608
data:
  {"annotated_genes":["SJAG_03588","SJAG_02641","SJAG_04376","SJAG_01630","SJAG_01179","SJAG_03957","SJAG_MIT13","SJAG_02384","SJAG_MIT15","SJAG_03972","SJAG_MIT03","SJAG_02848","SJAG_02656","SJAG_01816","SJAG_02007"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86122],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008134"},{"annotations":[85900,85901,85902],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010788"},{"annotations":[86253],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0020737"},{"annotations":[87186],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0015011"},{"annotations":[85741],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0033549"},{"annotations":[86131],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008135"},{"annotations":[86613],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957935"},{"annotations":[86408],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957978"},{"annotations":[85819],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008133"},{"annotations":[86027,86028],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012543"},{"annotations":[85793,85792],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014571"},{"annotations":[86979],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007429"}]},"cv_name":"mondo","definition":"A disorder characterized by loss of optic nerve fibers. It may be inherited or acquired. Acquired causes include ischemia, optic nerve neuropathy, glaucoma, trauma, radiation, brain tumors, and multiple sclerosis. It leads to vision disturbances.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"optic nerve disorder","termid":"MONDO:0002135"}],"gene_count":15,"genes_by_uniquename":{"SJAG_01179":null,"SJAG_01630":null,"SJAG_01816":null,"SJAG_02007":null,"SJAG_02384":null,"SJAG_02641":null,"SJAG_02656":null,"SJAG_02848":null,"SJAG_03588":null,"SJAG_03957":null,"SJAG_03972":null,"SJAG_04376":null,"SJAG_MIT03":null,"SJAG_MIT13":null,"SJAG_MIT15":null},"genotype_count":0,"is_obsolete":false,"name":"optic atrophy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:76976005","DOID:5723","MEDGEN:18180","ICD9:377.10","NCIT:C34863","icd11.foundation:568505454","UMLS:C0029124","ICD10CM:H47.2","ICD9:377.1","MESH:D009896"],"synonyms":[{"name":"atrophy of optic disc","type":"exact"},{"name":"atrophy of optic disk","type":"exact"}],"termid":"MONDO:0003608","terms_by_termid":{"MONDO:0007429":null,"MONDO:0008133":null,"MONDO:0008134":null,"MONDO:0008135":null,"MONDO:0010788":null,"MONDO:0012543":null,"MONDO:0014571":null,"MONDO:0015011":null,"MONDO:0020737":null,"MONDO:0033549":null,"MONDO:0957935":null,"MONDO:0957978":null},"xrefs":{"Monarch":{"xref_id":"0003608"}}}


id: PBO:0085057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-essential protein of unknown function; required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation; contains twin cysteine-x9-cysteine motifs; deletion affects mitochondrial morphology","termid":"PBO:0085057"}


id: MONDO:0015055
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acquired angioedema type 2 (AAE2) is a type of acquired angioedema (AAE) characterized by acute edema in subcutaneous tissues, viscera and/or the upper airway.","definition_xrefs":["Orphanet:100055"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acquired angioedema","termid":"MONDO:0019624"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"acquired angioedema type 2","secondary_identifiers":["MEDGEN:1814461","UMLS:C5680381","GARD:19747"],"synonyms":[{"name":"AAE 2","type":"exact"},{"name":"AAE II","type":"exact"},{"name":"acquired angioneurotic edema type 2","type":"exact"},{"name":"acquired angioneurotic oedema type 2","type":"exact"}],"termid":"MONDO:0015055","xrefs":{"Monarch":{"xref_id":"0015055"}}}


id: PBO:0076898
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed 52","termid":"PBO:0076898"}


id: MONDO:0958237
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"isolated hyperferritinemia","secondary_identifiers":["OMIM:620729","UMLS:C3854388","MEDGEN:892475"],"synonyms":[{"name":"hyperferritinemia","type":"exact"}],"termid":"MONDO:0958237","xrefs":{"Monarch":{"xref_id":"0958237"}}}


id: PBO:0084406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Lysophosphatidic acid acyltransferase; responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress; ICT1 has a paralog, ECM18, that arose from the whole genome duplication; human ABHD5 can complement ict1 null mutant","termid":"PBO:0084406"}


id: PBO:0087213
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S-adenosylmethionine-homocysteine methyltransferase; functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio; SAM4 has a paralog, YMR321C, that arose from a single-locus duplication","termid":"PBO:0087213"}


id: PBO:0071656
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L36 pseudogene 20","termid":"PBO:0071656"}


id: GO:0050506
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-D-glucose + vomilenine = H+ + raucaffricine + UDP.","definition_xrefs":["RHEA:19385","EC:2.4.1.219"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glucosyltransferase activity","termid":"GO:0035251"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824","GO:0016757"],"is_obsolete":false,"name":"vomilenine glucosyltransferase activity","secondary_identifiers":["KEGG_REACTION:R05882","MetaCyc:2.4.1.219-RXN"],"synonyms":[{"name":"UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity","type":"related"},{"name":"UDPG:vomilenine 21-beta-D-glucosyltransferase activity","type":"related"},{"name":"UDPG:vomilenine 21beta-D-glucosyltransferase activity","type":"related"},{"name":"vomilenine-glucosyltransferase activity","type":"related"}],"termid":"GO:0050506"}


id: GO:0007108
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process involved in starting cell separation.","definition_xrefs":["GOC:clt","GOC:dph","GOC:tb"],"gene_count":0,"genotype_count":0,"name":"obsolete cytokinesis, initiation of separation (obsolete GO:0007108)","synonyms":[{"name":"cytokinesis, initiation of separation","type":"exact"},{"name":"initiation of separation involved in cytokinesis","type":"exact"}],"termid":"GO:0007108"}


