# terms

id: PBO:0075535
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"speedy/RINGO cell cycle regulator family member E15","termid":"PBO:0075535"}


id: GO:0047016
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.","definition_xrefs":["EC:1.1.1.181","MetaCyc:1.1.1.181-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity","secondary_identifiers":["RHEA:11896"],"synonyms":[{"name":"3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity","type":"related"},{"name":"3beta-hydroxy-delta5-C27-steroid oxidoreductase","type":"broad"},{"name":"cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity","type":"related"},{"name":"cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity","type":"related"}],"termid":"GO:0047016"}


id: PBO:0002966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleotide reductase (RNR) inhibitor","termid":"PBO:0002966"}


id: PBO:0080158
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"valosin containing protein lysine methyltransferase","termid":"PBO:0080158"}


id: GO:0120155
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.","definition_xrefs":["PMID:24895401","PMID:24413167","GOC:rn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"cellular bud neck","termid":"GO:0005935"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"MIH complex","synonyms":[{"name":"Mlc1p-Iqg1p-Hof1p complex","type":"exact"}],"termid":"GO:0120155"}


id: MONDO:0003256
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A generally benign intrasellar and/or suprasellar mass arising from the neurohypophysis or infundibulum. It is composed of nests of large cells with granular, eosinophilic cytoplasm due to abundant intracytoplasmic lysosomes. It generally has a slow progression and lacks invasive growth. (Adapted from WHO)","definition_xrefs":["NCIT:C7017"],"direct_ancestors":[{"relation_name":"is_a","term_name":"posterior pituitary gland neoplasm","termid":"MONDO:0003257"},{"relation_name":"is_a","term_name":"granular cell tumor","termid":"MONDO:0006235"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurohypophysis granular cell tumor","secondary_identifiers":["MEDGEN:232255","SCTID:699331002","DOID:5047","EFO:1000285","ICDO:9582/0","UMLS:C1333873"],"synonyms":[{"name":"granular cell tumor of Neurohypophysis","type":"exact"},{"name":"granular cell tumor of neurohypophysis","type":"exact"},{"name":"granular cell tumor of the Neurohypophysis (WHO grade I)","type":"exact"},{"name":"granular cell tumor of the neurohypophysis","type":"exact"},{"name":"granular cell tumor of the posterior pituitary gland","type":"exact"},{"name":"granular cell tumour of Neurohypophysis","type":"exact"},{"name":"granular cell tumour of neurohypophysis","type":"exact"},{"name":"granular cell tumour of the Neurohypophysis (WHO grade I)","type":"exact"},{"name":"granular cell tumour of the neurohypophysis","type":"exact"},{"name":"granular cell tumour of the posterior pituitary gland","type":"exact"},{"name":"neurohypophysis granular cell tumor","type":"exact"}],"termid":"MONDO:0003256","xrefs":{"Monarch":{"xref_id":"0003256"}}}


id: PBO:0083988
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic","termid":"PBO:0083988"}


id: PBO:0050764
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family E (Hsp10) member 1 pseudogene 26","termid":"PBO:0050764"}


id: GO:0070173
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of tooth mineralization","termid":"GO:0070170"},{"relation_name":"regulates","term_name":"enamel mineralization","termid":"GO:0070166"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of enamel mineralization","termid":"GO:0070173"}


id: GO:0033861
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of NAD(P)H oxidase activity","termid":"GO:0033860"},{"relation_name":"is_a","term_name":"negative regulation of oxidoreductase activity","termid":"GO:0051354"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of NAD(P)H oxidase activity","synonyms":[{"name":"down regulation of NAD(P)H oxidase activity","type":"exact"},{"name":"down-regulation of NAD(P)H oxidase activity","type":"exact"},{"name":"downregulation of NAD(P)H oxidase activity","type":"exact"},{"name":"inhibition of NAD(P)H oxidase activity","type":"narrow"}],"termid":"GO:0033861"}


id: GO:0035951
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.","definition_xrefs":["GOC:dgf"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter (obsolete GO:0035951)","synonyms":[{"name":"positive regulation of oligopeptide transport by activation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of oligopeptide transport by positive regulation of transcription from Pol II promoter","type":"exact"},{"name":"positive regulation of oligopeptide transport by stimulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of oligopeptide transport by up regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of oligopeptide transport by up-regulation of transcription from RNA polymerase II promoter","type":"exact"},{"name":"positive regulation of oligopeptide transport by upregulation of transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:0035951"}


id: PBO:0088387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase activating protein, Tsc2 paralog","termid":"PBO:0088387"}


id: GO:0048256
data:
  {"annotated_genes":["SJAG_01648","SJAG_03994","SJAG_04183","SJAG_01044","SJAG_01173","SJAG_05237","SJAG_01832"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[74802],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0048257"},{"annotations":[74930,78716,71710,75979,66739,73199],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017108"}]},"cv_name":"molecular_function","definition":"Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA endonuclease activity","termid":"GO:0004520"},{"relation_name":"is_a","term_name":"hydrolase activity, acting on ester bonds","termid":"GO:0016788"}],"gene_count":7,"genes_by_uniquename":{"SJAG_01044":null,"SJAG_01173":null,"SJAG_01648":null,"SJAG_01832":null,"SJAG_03994":null,"SJAG_04183":null,"SJAG_05237":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0140097","GO:0016787","GO:0003824","GO:0003674","GO:0016788"],"is_obsolete":false,"name":"flap endonuclease activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null},"termid":"GO:0048256","terms_by_termid":{"GO:0017108":null,"GO:0048257":null}}


id: GO:0004623
data:
  {"annotated_genes":["SJAG_04323","SJAG_02091","SJAG_02093","SJAG_03204"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[71462,76879,77779,78925],"is_not":false,"summary":null,"term":"GO:0004623"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.","definition_xrefs":["RHEA:15801"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipase activity","termid":"GO:0004620"},{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":4,"genes_by_uniquename":{"SJAG_02091":null,"SJAG_02093":null,"SJAG_03204":null,"SJAG_04323":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016787","GO:0016788","GO:0003674"],"is_obsolete":false,"name":"phospholipase A2 activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-1482884","Reactome:R-HSA-1482897","MetaCyc:PHOSPHOLIPASE-A2-RXN","Reactome:R-HSA-1602398","Reactome:R-HSA-1482907","EC:3.1.1.4","Reactome:R-HSA-1602399","Reactome:R-HSA-1602446","Reactome:R-HSA-1482759","Reactome:R-HSA-1482745","Reactome:R-HSA-1482856","Reactome:R-HSA-1482816","Reactome:R-HSA-1482771","Reactome:R-HSA-1482825","Reactome:R-HSA-8848484","Reactome:R-HSA-1482604","Reactome:R-HSA-1482900","Reactome:R-HSA-1602377","Reactome:R-HSA-1482656","Reactome:R-HSA-1602374","Reactome:R-HSA-1482679","Reactome:R-HSA-1482887","Reactome:R-HSA-1482868","GO:0102567","Reactome:R-HSA-1482778","Reactome:R-HSA-1602368","Reactome:R-HSA-1602417","GO:0102568","MetaCyc:RXN-15067","Reactome:R-HSA-1482776"],"synonyms":[{"name":"cytosolic phospholipase A2 activity","type":"narrow"},{"name":"lecithinase A activity","type":"related"},{"name":"phosphatidase activity","type":"related"},{"name":"phosphatidolipase activity","type":"related"},{"name":"phosphatidylcholine 2-acylhydrolase activity","type":"related"},{"name":"phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)","type":"narrow"},{"name":"phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)","type":"narrow"},{"name":"secreted phospholipase A2 activity","type":"narrow"}],"termid":"GO:0004623","terms_by_termid":{"GO:0004623":null}}


id: MONDO:0020721
data:
  {"annotated_genes":["SJAG_03961"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87085],"is_not":false,"summary":null,"term":"MONDO:0020721"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"},{"relation_name":"is_a","term_name":"inborn disorder of porphyrin metabolism","termid":"MONDO:0017754"},{"relation_name":"is_a","term_name":"inherited sideroblastic anemia","termid":"MONDO:0020099"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03961":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0002280","MONDO:0005570","MONDO:0005066"],"is_obsolete":false,"name":"X-linked sideroblastic anemia 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0060063","GARD:9456","MEDGEN:1638704","SCTID:62677000","OMIM:300751","MESH:C536761","UMLS:C4551511","Orphanet:75563"],"synonyms":[{"name":"ANH1","type":"related"},{"name":"SIDBA1","type":"related"},{"name":"X chromosome-linked sideroblastic anaemia","type":"related"},{"name":"X chromosome-linked sideroblastic anemia","type":"related"},{"name":"X-linked sideroblastic anaemia","type":"exact"},{"name":"X-linked sideroblastic anemia","type":"exact"},{"name":"XLSA","type":"exact"},{"name":"anaemia hereditary sideroblastic","type":"related"},{"name":"anaemia sex-linked hypochromic sideroblastic","type":"related"},{"name":"anemia hereditary sideroblastic","type":"related"},{"name":"anemia sex-linked hypochromic sideroblastic","type":"related"},{"name":"anemia, hereditary sideroblastic","type":"related"},{"name":"anemia, hypochromic","type":"related"},{"name":"anemia, sideroblastic, 1","type":"related"},{"name":"anemia, sideroblastic, 1, X-linked recessive","type":"exact"},{"name":"anemia, sideroblastic, X-linked","type":"related"},{"name":"erythroid 5-aminolevulinate synthase deficiency","type":"related"},{"name":"hereditary iron-loading Anaemia","type":"related"},{"name":"hereditary iron-loading Anemia","type":"related"},{"name":"sideroblastic anaemia X-linked","type":"related"},{"name":"sideroblastic anemia X-linked","type":"related"},{"name":"sideroblastic anemia, X-linked","type":"exact"}],"termid":"MONDO:0020721","terms_by_termid":{"MONDO:0020721":null},"xrefs":{"Monarch":{"xref_id":"0020721"}}}


id: MONDO:0020398
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital mitral stenosis is a congenital heart malformation comprising a spectrum of morphologically heterogeneous developmental anomalies that result in functional and anatomic obstruction of inflow into the left ventricle. The structure of the mitral valve is affected at the level of the supravalvular ring, annulus, leaflets or subvalvar copmponents and include supra-valvular ring, leaflet fusion (intra-leaflet ring), mitral parachute deformity and papillary muscle abnormalities. It may be isolated or associated with other heart malformations. The clinical presentation depends on the degree of obstruction, the presence of regurgitation, the presence and severity of associated pulmonary hypertension, and the presence of associated heart malformations. It may present with symptoms and signs of low cardiac output and right ventricular failure such as pulmonary infections, failure to thrive, exertional dyspnea, cough, cyanosis and congestive heart failure.","definition_xrefs":["Orphanet:99057"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitral valve stenosis","termid":"MONDO:0005852"},{"relation_name":"is_a","term_name":"congenital mitral valve insufficiency and/or stenosis","termid":"MONDO:0019817"},{"relation_name":"is_a","term_name":"inherited mitral valve disease","termid":"MONDO:0042966"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"congenital mitral stenosis","secondary_identifiers":["HP:0011570","ICD9:746.5","UMLS:C0158618","ICD10CM:Q23.2","NANDO:1200963","SCTID:82458004","GARD:1496","icd11.foundation:2102952411","MEDGEN:57857"],"synonyms":[{"name":"congenital mitral stenosis","type":"exact"},{"name":"congenital mitral stenosis (disease)","type":"exact"},{"name":"congenital mitral valve stenosis","type":"exact"},{"name":"hereditary mitral valve stenosis","type":"exact"}],"termid":"MONDO:0020398","xrefs":{"Monarch":{"xref_id":"0020398"}}}


id: PBO:0112607
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SIN signalling inhibitor, two-component GAP Cdc16","termid":"PBO:0112607"}


id: MONDO:0013320
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"16p11.2-p12.2 microdeletion syndrome is a recently described syndrome characterized by developmental delay and facial dysmorphism.","definition_xrefs":["Orphanet:261211"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of the short arm of chromosome 16","termid":"MONDO:0016894"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 16p12.2-p11.2 deletion syndrome","secondary_identifiers":["MEDGEN:462208","GARD:17243","OMIM:613604","SCTID:719576009","UMLS:C3150858","DOID:0060400","DECIPHER:68"],"synonyms":[{"name":"16p11.2-p12.2 microdeletion syndrome","type":"exact"},{"name":"16p11.2p12.2 microdeletion syndrome","type":"exact"},{"name":"Del(16)(p11.2p12.2)","type":"exact"},{"name":"chromosome 16p12.2-p11.2 deletion syndrome, 7.1- to 8.7-MB","type":"related"},{"name":"chromosome 16p12.2-p11.2 deletion syndrome, isolated cases","type":"exact"},{"name":"monosomy 16p11.2-p12.2","type":"exact"},{"name":"monosomy 16p11.2p12.2","type":"exact"}],"termid":"MONDO:0013320","xrefs":{"Monarch":{"xref_id":"0013320"}}}


id: FYPO:0002699
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to cell cortex during vegetative growth","termid":"FYPO:0000929"},{"relation_name":"is_a","term_name":"abnormal protein localization to actomyosin contractile ring","termid":"FYPO:0002560"},{"relation_name":"is_a","term_name":"decreased protein localization to cell division site","termid":"FYPO:0002869"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001320","FYPO:0001985","FYPO:0000032","FYPO:0000631","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"decreased protein localization to actomyosin contractile ring","synonyms":[{"name":"decreased protein localisation to actomyosin contractile ring","type":"exact"},{"name":"decreased protein localization to actomyosin contractile ring during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to actomyosin contractile ring during vegetative growth","type":"exact"},{"name":"decreased protein localization to actomyosin contractile ring involved in mitotic cytokinesis","type":"exact"},{"name":"decreased protein localization to cytokinetic contractile ring","type":"exact"},{"name":"decreased protein localization to mitotic contractile ring","type":"exact"},{"name":"decreased protein recruitment to actomyosin contractile ring","type":"related"},{"name":"reduced protein localization to actomyosin contractile ring","type":"exact"}],"termid":"FYPO:0002699"}


id: PATO:0001910
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A surface feature shape quality inhering in a bearer by virtue of the bearer's one part being layered over another connected part.","definition_xrefs":["PATOC:cjm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"surface feature shape","termid":"PATO:0001925"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"folded","termid":"PATO:0001910"}


id: PBO:0001743
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial fusion and transport protein Ugo1 (predicted)","termid":"PBO:0001743"}


id: GO:0032226
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of synaptic transmission, dopaminergic","termid":"GO:0032225"},{"relation_name":"is_a","term_name":"positive regulation of synaptic transmission","termid":"GO:0050806"},{"relation_name":"positively_regulates","term_name":"synaptic transmission, dopaminergic","termid":"GO:0001963"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of synaptic transmission, dopaminergic","synonyms":[{"name":"activation of synaptic transmission, dopaminergic","type":"narrow"},{"name":"stimulation of synaptic transmission, dopaminergic","type":"narrow"},{"name":"up regulation of synaptic transmission, dopaminergic","type":"exact"},{"name":"up-regulation of synaptic transmission, dopaminergic","type":"exact"},{"name":"upregulation of synaptic transmission, dopaminergic","type":"exact"}],"termid":"GO:0032226"}


id: MONDO:0008188
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"papillomatosis, confluent and reticulated","secondary_identifiers":["UMLS:C0263385","MESH:C566832","OMIM:167900","MEDGEN:472991"],"synonyms":[{"name":"carp","type":"related"},{"name":"papillomatosis, confluent and reticulated","type":"exact"},{"name":"papillomatosis, familial cutaneous","type":"related"},{"name":"papillomatosis, reticulated and confluent, of Gougerot and Carteaud","type":"related"}],"termid":"MONDO:0008188","xrefs":{"Monarch":{"xref_id":"0008188"}}}


id: GO:0051507
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete beta-sitosterol UDP-glucosyltransferase activity (obsolete GO:0051507)","termid":"GO:0051507"}


id: PBO:0088020
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tyrosyl-DNA phosphodiesterase I; hydrolyzes 3' and 5'-phosphotyrosyl bonds; involved in the repair of DNA lesions created by topo I and topo II; mutations in the human homolog, TDP1, result in the a neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy (SCAN1); yeast cells and human rhabdomyosarcoma lines that overexpress TDP1 both exhibit elevated dosage chromosomal instability (dCIN)","termid":"PBO:0088020"}


id: PBO:0075963
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"STARD4 antisense RNA 1","termid":"PBO:0075963"}


id: PBO:0067937
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 239","termid":"PBO:0067937"}


id: PBO:0070218
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 151 pseudogene","termid":"PBO:0070218"}


id: PBO:0078535
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 27","termid":"PBO:0078535"}


id: PATO:0001460
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A sensitivity of a process inhering in a biological process by virtue of the process unfolding in a location without oxygen.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitivity of a process to oxygen","termid":"PATO:0001458"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anaerobic (for occurrence)","termid":"PATO:0001460"}


id: PBO:0068961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 205, pseudogene","termid":"PBO:0068961"}


id: PBO:0076634
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transducin beta like 1 Y-linked pseudogene 1","termid":"PBO:0076634"}


id: SO:0000141
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The sequence of DNA located either at the end of the transcript that causes RNA polymerase to terminate transcription.","direct_ancestors":[{"relation_name":"is_a","term_name":"transcriptional_cis_regulatory_region","termid":"SO:0001055"},{"relation_name":"part_of","term_name":"transcript","termid":"SO:0000673"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"terminator","secondary_identifiers":["http://en.wikipedia.org/wiki/Terminator_(genetics)"],"synonyms":[{"name":"INSDC_feature:regulatory","type":"broad"},{"name":"INSDC_qualifier:terminator","type":"exact"},{"name":"terminator sequence","type":"exact"}],"termid":"SO:0000141"}


id: GO:0004386
data:
  {"annotated_genes":["SJAG_01354","SJAG_02835","SJAG_00857","SJAG_01152","SJAG_05173","SJAG_00884","SJAG_03923","SJAG_16455","SJAG_03036","SJAG_00995","SJAG_06597","SJAG_02295","SJAG_03730","SJAG_04372","SJAG_02061","SJAG_02822","SJAG_04183","SJAG_02558","SJAG_05105","SJAG_03157","SJAG_05025","SJAG_02242","SJAG_01221","SJAG_01953","SJAG_02348","SJAG_00583","SJAG_04669","SJAG_00887","SJAG_02991","SJAG_02199","SJAG_04230","SJAG_04355","SJAG_02294","SJAG_00986","SJAG_00616","SJAG_04974","SJAG_02686","SJAG_03886","SJAG_03077","SJAG_04589","SJAG_02200","SJAG_03479","SJAG_01677","SJAG_05372","SJAG_04064","SJAG_06642","SJAG_00898","SJAG_03780","SJAG_04118","SJAG_02382","SJAG_03495","SJAG_03193","SJAG_04650","SJAG_04480","SJAG_01762","SJAG_04772","SJAG_01182","SJAG_05353","SJAG_00786","SJAG_01644","SJAG_04081","SJAG_00597","SJAG_05276","SJAG_03206","SJAG_02690","SJAG_03898","SJAG_01499","SJAG_01315","SJAG_03897","SJAG_02287","SJAG_02879","SJAG_04210","SJAG_00798","SJAG_03533"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70625],"is_not":false,"summary":null,"term":"GO:0004386"},{"annotations":[78337,70719,113335,75128,78485,74992,71175,113333,73834,111333,79811,113331,113332,114669,78042],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043138"},{"annotations":[115665,106803,107615],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033679"},{"annotations":[74416],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034458"},{"annotations":[92541,58953,77215],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043139"},{"annotations":[100251,112909],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033678"},{"annotations":[100252],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032574"},{"annotations":[89540,72416,76669,77063,73178],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003678"},{"annotations":[90167,79216,118575],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036121"},{"annotations":[79219],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061749"},{"annotations":[78488,78341,71178,79815],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009378"},{"annotations":[77533,101776,115810,79071,96361,60600,108169,61609,103898,67938,69707,103498,57703,80746,72395,116748,65414,107651,72230,119058,60198,74335,75812,62577,79403,99699,79581,76491,79969,106151,58080,72206,75688,58877,75954,88137,101003,74494,57197,63896,75943],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0003724"},{"annotations":[70343,107618,109465,115669],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990518"},{"annotations":[73837,64098,73651,74995,78946,112918],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017116"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleic acid conformation isomerase activity","termid":"GO:0120545"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a nucleic acid","termid":"GO:0140640"},{"relation_name":"is_a","term_name":"ATP-dependent 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activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000003":null,"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0008026","Reactome:R-HSA-5686410","Reactome:R-HSA-169461","Reactome:R-HSA-5690996","Reactome:R-HSA-169468"],"synonyms":[{"name":"ATP-dependent helicase activity","type":"exact"}],"termid":"GO:0004386","terms_by_termid":{"GO:0003678":null,"GO:0003724":null,"GO:0004386":null,"GO:0009378":null,"GO:0017116":null,"GO:0032574":null,"GO:0033678":null,"GO:0033679":null,"GO:0034458":null,"GO:0036121":null,"GO:0043138":null,"GO:0043139":null,"GO:0061749":null,"GO:1990518":null}}


id: PBO:0063170
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAXIP1 antisense RNA 2","termid":"PBO:0063170"}


id: PBO:0049422
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GULP PTB domain containing engulfment adaptor 1","termid":"PBO:0049422"}


id: MONDO:0018006
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Adult-onset distal myopathy due to VCP mutation is a rare, genetic distal myopathy disorder characterized by middle age-onset of distal leg muscle weakness, atrophy in the anterior compartment resulting in foot drop, without proximal or scapular skeletal muscle weakness. Rapidly progressive dementia, Paget disease of bone and hand weakness have been reported. Muscle biopsy shows pronounced myopathic changes with rimmed vacuoles.","definition_xrefs":["Orphanet:329478"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant distal myopathy","termid":"MONDO:0016108"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0005336"],"is_obsolete":false,"name":"adult-onset distal myopathy due to VCP mutation","secondary_identifiers":["GARD:21492","MEDGEN:1660404","UMLS:C4749506"],"termid":"MONDO:0018006","xrefs":{"Monarch":{"xref_id":"0018006"}}}


id: GO:0043288
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoprenoid metabolic process","termid":"GO:0006720"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"apocarotenoid metabolic process","synonyms":[{"name":"apo carotenoid metabolic process","type":"exact"},{"name":"apocarotenoid metabolism","type":"exact"}],"termid":"GO:0043288"}


id: PBO:0086160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase activity and biphasic release to promote rDNA repeat segregation; required for condensin recruitment to the replication fork barrier site; TOF2 has a paralog, NET1, that arose from the whole genome duplication","termid":"PBO:0086160"}


id: RO:0002213
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.","direct_ancestors":[{"relation_name":"is_a","term_name":"regulates","termid":"RO:0002211"},{"relation_name":"is_a","term_name":"causally_upstream_of,_positive_effect","termid":"RO:0002304"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"positively_regulates","termid":"RO:0002213"}


id: PBO:0076081
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small transmembrane regulator of ion transport 1","termid":"PBO:0076081"}


id: MONDO:1011531
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hyperadrenocorticism that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hyperadrenocorticism, non-human animal","termid":"MONDO:1011403"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperadrenocorticism, domestic cat","secondary_identifiers":["OMIA:000494-9685"],"termid":"MONDO:1011531","xrefs":{"Monarch":{"xref_id":"1011531"}}}


id: GO:0051065
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.","definition_xrefs":["MetaCyc:1.17.4.2-RXN"],"gene_count":0,"genotype_count":0,"name":"obsolete CTP reductase activity (obsolete GO:0051065)","synonyms":[{"name":"CTP reduction","type":"related"}],"termid":"GO:0051065"}


id: PR:O94590
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sec1 gene.","definition_xrefs":["UniProtKB:O94590","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein transport protein sec1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC584.05","synonyms":[{"name":"Spom972h-sec1","type":"exact"}],"termid":"PR:O94590"}


id: MONDO:0015448
data:
  {"annotated_genes":["SJAG_00601","SJAG_05305","SJAG_00080","SJAG_01490","SJAG_03099","SJAG_00755","SJAG_00354","SJAG_02646","SJAG_04560","SJAG_01405","SJAG_03490"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87063],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032909"},{"annotations":[86084],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0859321"},{"annotations":[86838],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007415"},{"annotations":[85502],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014063"},{"annotations":[85503],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014064"},{"annotations":[85501],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014065"},{"annotations":[85505],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014066"},{"annotations":[86302],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014194"},{"annotations":[86786],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014356"},{"annotations":[86792],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014364"},{"annotations":[87066],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014496"}]},"cv_name":"mondo","definition":"Isolated complex III deficiency is a rare, genetic, mitochondrial oxidative phosphorylation disorder characterized by a wide spectrum of clinical manifestations ranging from isolated myopathy or transient hepatopathy to severe multisystem disorder (that may include hypotonia, failure to thrive, psychomotor delay, cardiomyopathy, encephalopathy, renal tubulopathy, hearing impairment, lactic acidosis, hypoglycemia and other signs and symptoms).","definition_xrefs":["Orphanet:1460"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial complex deficiency","termid":"MONDO:0000066"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00080":null,"SJAG_00354":null,"SJAG_00601":null,"SJAG_00755":null,"SJAG_01405":null,"SJAG_01490":null,"SJAG_02646":null,"SJAG_03099":null,"SJAG_03490":null,"SJAG_04560":null,"SJAG_05305":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0005066"],"is_obsolete":false,"name":"mitochondrial complex III deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:377658","UMLS:C1852372","GARD:8295","DOID:0111139"],"synonyms":[{"name":"isolated CoQ-cytochrome C reductase deficiency","type":"exact"},{"name":"isolated coenzyme Q-cytochrome C reductase deficiency","type":"exact"},{"name":"isolated complex III deficiency","type":"related"},{"name":"isolated mitochondrial respiratory chain complex III deficiency","type":"exact"},{"name":"isolated ubiquinone-cytochrome C reductase deficiency","type":"exact"}],"termid":"MONDO:0015448","terms_by_termid":{"MONDO:0007415":null,"MONDO:0014063":null,"MONDO:0014064":null,"MONDO:0014065":null,"MONDO:0014066":null,"MONDO:0014194":null,"MONDO:0014356":null,"MONDO:0014364":null,"MONDO:0014496":null,"MONDO:0032909":null,"MONDO:0859321":null},"xrefs":{"Monarch":{"xref_id":"0015448"}}}


id: GO:0102355
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H+.","definition_xrefs":["EC:3.1.1.91","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016788","GO:0016787"],"is_obsolete":false,"name":"2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity","secondary_identifiers":["MetaCyc:RXN-13371","RHEA:33967"],"termid":"GO:0102355"}


id: PBO:0046449
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EPPIN-WFDC6 readthrough","termid":"PBO:0046449"}


id: GO:0034113
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The attachment of a cell to a cell of a different type via adhesion molecules.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell adhesion","termid":"GO:0098609"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"heterotypic cell-cell adhesion","termid":"GO:0034113"}


id: MONDO:1010838
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Galactosialidosis that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactosialidosis, non-human animal","termid":"MONDO:1010166"},{"relation_name":"is_a","term_name":"lysosomal storage disease, dog","termid":"MONDO:1010860"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"galactosialidosis, dog","secondary_identifiers":["OMIA:000400-9615"],"termid":"MONDO:1010838","xrefs":{"Monarch":{"xref_id":"1010838"}}}


id: MONDO:0014406
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any pancreatic agenesis in which the cause of the disease is a mutation in the PTF1A gene.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreatic agenesis","termid":"MONDO:0009832"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pancreatic agenesis 2","secondary_identifiers":["OMIM:615935","MEDGEN:863174","GARD:16033","UMLS:C4014737"],"synonyms":[{"name":"PAGEN2","type":"related"},{"name":"PTF1A pancreatic agenesis","type":"exact"},{"name":"pancreatic agenesis 2","type":"exact"},{"name":"pancreatic agenesis caused by mutation in PTF1A","type":"exact"},{"name":"pancreatic agenesis type 2","type":"exact"},{"name":"pancreatic hypoplasia, congenital 2","type":"related"}],"termid":"MONDO:0014406","xrefs":{"Monarch":{"xref_id":"0014406"}}}


id: PBO:0055894
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 14B","termid":"PBO:0055894"}


id: PBO:0002787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"urease Ure2","termid":"PBO:0002787"}


id: FYPO:0005423
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule in the mitotic spindle, occurs to a lesser extent than normal during anaphase A.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased mitotic spindle microtubule depolymerization","termid":"FYPO:0004650"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0000054","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased mitotic spindle microtubule depolymerization during mitotic anaphase A","synonyms":[{"name":"decreased mitotic spindle microtubule catastrophe during anaphase A","type":"related"},{"name":"decreased mitotic spindle microtubule depolymerisation during anaphase A","type":"exact"},{"name":"decreased mitotic spindle microtubule depolymerization during anaphase A during vegetative growth","type":"exact"},{"name":"decreased mitotic spindle microtubule depolymerization during movement of chromosomes towards separated spindle pole bodies","type":"exact"},{"name":"decreased mitotic spindle microtubule shrinkage during anaphase A","type":"related"},{"name":"decreased spindle microtubule depolymerization during anaphase A during mitotic cell cycle","type":"exact"},{"name":"reduced mitotic spindle microtubule depolymerization during anaphase A","type":"exact"}],"termid":"FYPO:0005423"}


id: GO:0102044
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor = 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.","definition_xrefs":["GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor","termid":"GO:0016708"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"3-chlorobenzoate-4,5-oxygenase activity","secondary_identifiers":["MetaCyc:RXN-10421"],"termid":"GO:0102044"}


id: MOD:01349
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod Chemical derivative -","definition_xrefs":["Unimod:320#C"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolyzed N-ethylmaleimide adduct","termid":"MOD:00631"},{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"hydrolyzed N-ethylmaleimide cysteine adduct","synonyms":[{"name":"Nethylmaleimide+water","type":"related"},{"name":"Nethylmaleimidehydrolysis","type":"related"}],"termid":"MOD:01349"}


id: PR:O13774
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A GTP cyclohydrolase 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00727"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTP cyclohydrolase 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17A5.13","secondary_identifiers":["UniProtKB:O13774"],"synonyms":[{"name":"GTP cyclohydrolase I (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"GTP-CH-I (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-GCH1","type":"exact"}],"termid":"PR:O13774"}


id: MONDO:0000099
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete trichoepithelioma, multiple familial (obsolete MONDO:0000099)","termid":"MONDO:0000099","xrefs":{"Monarch":{"xref_id":"0000099"}}}


id: MONDO:0004166
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Fallopian tube carcinoma that has developed in relatives of patients that have a history of fallopian tube carcinoma.","definition_xrefs":["NCIT:C40455"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"fallopian tube carcinoma","termid":"MONDO:0006206"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"hereditary fallopian tube carcinoma","secondary_identifiers":["UMLS:C1512418","MEDGEN:307556","DOID:7266"],"synonyms":[{"name":"familial fallopian tube carcinoma","type":"exact"},{"name":"familiar fallopian tube carcinoma","type":"related"},{"name":"hereditary fallopian tube cancer","type":"exact"},{"name":"hereditary fallopian tube carcinoma","type":"exact"}],"termid":"MONDO:0004166","xrefs":{"Monarch":{"xref_id":"0004166"}}}


id: PBO:0062244
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily BK member 1 pseudogene","termid":"PBO:0062244"}


id: MONDO:0007451
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"nephrogenic diabetes insipidus","termid":"MONDO:0016383"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"diabetes insipidus, nephrogenic, autosomal","secondary_identifiers":["GARD:15058","UMLS:C1563706","DOID:0081061","OMIM:125800","MEDGEN:289643"],"synonyms":[{"name":"diabetes insipidus, nephrogenic, 2","type":"exact"},{"name":"diabetes insipidus, nephrogenic, autosomal","type":"exact"},{"name":"diabetes insipidus, nephrogenic, type 2","type":"related"}],"termid":"MONDO:0007451","xrefs":{"Monarch":{"xref_id":"0007451"}}}


id: GO:0045967
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that reduces the rate of growth of all or part of an organism.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of growth rate","termid":"GO:0040009"},{"relation_name":"is_a","term_name":"negative regulation of growth","termid":"GO:0045926"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of growth rate","synonyms":[{"name":"down regulation of growth rate","type":"exact"},{"name":"down-regulation of growth rate","type":"exact"},{"name":"downregulation of growth rate","type":"exact"},{"name":"inhibition of growth rate","type":"narrow"}],"termid":"GO:0045967"}


id: GO:0061621
data:
  {"annotated_genes":["SJAG_00605","SJAG_04495","SJAG_02135","SJAG_00839","SJAG_02107","SJAG_03373","SJAG_06621","SJAG_02945","SJAG_06622","SJAG_00027","SJAG_03903","SJAG_04192","SJAG_04334","SJAG_02009","SJAG_00461","SJAG_02796","SJAG_03828","SJAG_02369","SJAG_03660","SJAG_01310"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[78226,94888,95382,98353,98623,103749,104005,105825,105826,105827,106196,106197,109767,109768,109769,109770,109771,109772,109773,116732],"is_not":false,"summary":null,"term":"GO:0061621"}]},"cv_name":"biological_process","definition":"The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.","definition_xrefs":["GOC:dph","ISBN:0201090910","ISBN:0879010479"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NADH metabolic process","termid":"GO:0006734"},{"relation_name":"is_a","term_name":"glycolytic process through glucose-6-phosphate","termid":"GO:0061620"},{"relation_name":"is_a","term_name":"glucose catabolic process to pyruvate","termid":"GO:0061718"}],"gene_count":20,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00461":null,"SJAG_00605":null,"SJAG_00839":null,"SJAG_01310":null,"SJAG_02009":null,"SJAG_02107":null,"SJAG_02135":null,"SJAG_02369":null,"SJAG_02796":null,"SJAG_02945":null,"SJAG_03373":null,"SJAG_03660":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04192":null,"SJAG_04334":null,"SJAG_04495":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0044281","GO:0008150","GO:0055086","GO:0006091"],"is_obsolete":false,"name":"canonical glycolysis","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["MetaCyc:ANAGLYCOLYSIS-PWY","Wikipedia:Glycolysis","Reactome:R-HSA-70171"],"termid":"GO:0061621","terms_by_termid":{"GO:0061621":null}}


id: MONDO:0014699
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal dominant non-syndromic intellectual disability in which the cause of the disease is a mutation in the CHAMP1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intellectual disability, autosomal dominant","termid":"MONDO:0100172"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"intellectual disability, autosomal dominant 40","secondary_identifiers":["MEDGEN:1810363","UMLS:C5676894","DOID:0070070","GARD:13539","OMIM:616579"],"synonyms":[{"name":"CHAMP1 autosomal dominant non-syndromic intellectual disability","type":"exact"},{"name":"MRD40","type":"exact"},{"name":"autosomal dominant intellectual disability 40","type":"exact"},{"name":"autosomal dominant mental retardation 40","type":"exact"},{"name":"autosomal dominant non-syndromic intellectual disability 40","type":"related"},{"name":"autosomal dominant non-syndromic intellectual disability caused by mutation in CHAMP1","type":"exact"},{"name":"intellectual disability, autosomal dominant 40","type":"exact"},{"name":"intellectual disability, autosomal dominant type 40","type":"exact"},{"name":"mental retardation, autosomal dominant 40","type":"related"},{"name":"mental retardation, autosomal dominant type 40","type":"exact"}],"termid":"MONDO:0014699","xrefs":{"Monarch":{"xref_id":"0014699"}}}


id: PBO:0077480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 200C","termid":"PBO:0077480"}


id: PBO:0071823
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S2 pseudogene 18","termid":"PBO:0071823"}


id: GO:0032517
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1.","definition_xrefs":["PMID:17324120","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein-containing complex","termid":"GO:0140535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"SOD1-calcineurin complex","termid":"GO:0032517"}


id: PBO:0111649
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Set1C complex and Lid2 complex subunit Ash2-trithorax family","termid":"PBO:0111649"}


id: FYPO:0002931
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which polyadenylated RNA molecules have poly(A) tails of that are longer than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal poly(A) tail length","termid":"FYPO:0002929"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002929"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002929","FYPO:0001985"],"is_obsolete":false,"name":"increased poly(A) tail length","synonyms":[{"name":"increased polyA sequence length","type":"exact"},{"name":"increased polyA tail length","type":"exact"},{"name":"long poly(a) tails","type":"exact"}],"termid":"FYPO:0002931"}


id: MONDO:0007763
data:
  {"annotated_genes":["SJAG_00440","SJAG_02231","SJAG_03787"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87144,87145,87146],"is_not":false,"summary":null,"term":"MONDO:0007763"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"renal cell carcinoma","termid":"MONDO:0005086"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00440":null,"SJAG_02231":null,"SJAG_03787":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005240"],"is_obsolete":false,"name":"nonpapillary renal cell carcinoma","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:144700","DOID:0050387"],"synonyms":[{"name":"CCRCC","type":"narrow"},{"name":"RCC","type":"related"},{"name":"adenocarcinoma of kidney","type":"related"},{"name":"clear cell renal cell adenocarcinoma","type":"narrow"},{"name":"clear cell renal cell carcinoma","type":"narrow"},{"name":"hypernephroma","type":"related"},{"name":"nonpapillary renal carcinoma 1 locus","type":"related"},{"name":"renal carcinoma, chromophobe, somatic","type":"exact"},{"name":"renal cell carcinoma","type":"broad"},{"name":"renal cell carcinoma, clear cell","type":"exact"},{"name":"renal cell carcinoma, clear cell, somatic","type":"exact"},{"name":"renal cell carcinoma, nonpapillary","type":"related"},{"name":"renal cell carcinoma, somatic","type":"exact"}],"termid":"MONDO:0007763","terms_by_termid":{"MONDO:0007763":null},"xrefs":{"Monarch":{"xref_id":"0007763"}}}


id: GO:0034204
data:
  {"annotated_genes":["SJAG_05209","SJAG_03209","SJAG_00587","SJAG_00669","SJAG_01470","SJAG_01731","SJAG_02897","SJAG_00018","SJAG_02943","SJAG_01095","SJAG_02516","SJAG_01945","SJAG_00230","SJAG_03050","SJAG_02581","SJAG_06440","SJAG_04734","SJAG_00589","SJAG_02114","SJAG_00576","SJAG_02957","SJAG_02132","SJAG_03774"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[102696,68999],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140331"},{"annotations":[77371,94786],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034203"},{"annotations":[102575,90885,109888,72517,60066,90880,90881,90884,90886,73238,99833,90887,90879,74903,90882,73398,90883,75161,101645],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045332"},{"annotations":[73574],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017121"}]},"cv_name":"biological_process","definition":"The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid transport","termid":"GO:0006869"},{"relation_name":"is_a","term_name":"regulation of membrane lipid distribution","termid":"GO:0097035"}],"gene_count":23,"genes_by_uniquename":{"SJAG_00018":null,"SJAG_00230":null,"SJAG_00576":null,"SJAG_00587":null,"SJAG_00589":null,"SJAG_00669":null,"SJAG_01095":null,"SJAG_01470":null,"SJAG_01731":null,"SJAG_01945":null,"SJAG_02114":null,"SJAG_02132":null,"SJAG_02516":null,"SJAG_02581":null,"SJAG_02897":null,"SJAG_02943":null,"SJAG_02957":null,"SJAG_03050":null,"SJAG_03209":null,"SJAG_03774":null,"SJAG_04734":null,"SJAG_05209":null,"SJAG_06440":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0051179","GO:0061024","GO:0008150"],"is_obsolete":false,"name":"lipid translocation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"intramembrane lipid transfer","type":"exact"}],"termid":"GO:0034204","terms_by_termid":{"GO:0017121":null,"GO:0034203":null,"GO:0045332":null,"GO:0140331":null}}


id: MOD:01182
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that crosslinks a cysteine and a histidine residue by forming the adduct 6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FAD.","definition_xrefs":["RESID:AA0436"],"direct_ancestors":[{"relation_name":"is_a","term_name":"FAD modified residue","termid":"MOD:00895"},{"relation_name":"is_a","term_name":"flavin crosslinked residues","termid":"MOD:01621"},{"relation_name":"is_a","term_name":"crosslinked L-cysteine residue","termid":"MOD:02044"},{"relation_name":"is_a","term_name":"crosslinked L-histidine residue","termid":"MOD:02048"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"6-(S-L-cysteinyl)-8alpha-(-3'-L-histidino)-FAD","synonyms":[{"name":"6-((R)-2-amino-2-carboxyethyl)sulfanyl-8alpha-[4-((S)-2-amino-2-carboxyethyl)imidazol-3-yl]-riboflavin 5'-(trihydrogen diphosphate) 5'->5'-ester with adenosine","type":"exact"},{"name":"6-(S-L-cysteinyl)-8alpha-(N3'-L-histidino)-FAD","type":"exact"},{"name":"6-(S-cysteinyl)-8alpha-(N(delta1)-histidyl)-FAD","type":"exact"},{"name":"6-(S-cysteinyl)-8alpha-(N(pi)-histidyl)-FAD","type":"exact"},{"name":"6-(S-cysteinyl)-8alpha-(N3'-histidyl)-FAD","type":"exact"},{"name":"6-(S-cysteinyl)-8alpha-(pros-histidyl)-FAD","type":"exact"},{"name":"BINDING FAD (covalent; via 2 links)","type":"exact"},{"name":"BINDING FAD (covalent; via 2 links, pros nitrogen)","type":"exact"},{"name":"CROSSLNK 6-(S-cysteinyl)-8alpha-(pros-histidyl)-FAD (His-Cys)","type":"exact"},{"name":"SCys6-NprosHis8a-FAD","type":"exact"}],"termid":"MOD:01182"}


id: GO:0052523
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by organism of symbiont programmed cell death (obsolete GO:0052523)","synonyms":[{"name":"enhancement or induction of symbiont programmed cell death","type":"exact"},{"name":"positive regulation by organism of symbiont programmed cell death","type":"exact"}],"termid":"GO:0052523"}


id: GO:0070857
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ketone metabolic process","termid":"GO:0010565"},{"relation_name":"is_a","term_name":"regulation of steroid biosynthetic process","termid":"GO:0050810"},{"relation_name":"is_a","term_name":"regulation of bile acid metabolic process","termid":"GO:1904251"},{"relation_name":"regulates","term_name":"bile acid biosynthetic process","termid":"GO:0006699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0006629","GO:0044281"],"is_obsolete":false,"name":"regulation of bile acid biosynthetic process","synonyms":[{"name":"regulation of bile acid anabolism","type":"exact"},{"name":"regulation of bile acid biosynthesis","type":"exact"},{"name":"regulation of bile acid formation","type":"exact"},{"name":"regulation of bile acid synthesis","type":"exact"}],"termid":"GO:0070857"}


id: MONDO:0012240
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any nemaline myopathy in which the cause of the disease is a mutation in the TPM2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"typical nemaline myopathy","termid":"MONDO:0015737"},{"relation_name":"is_a","term_name":"childhood-onset nemaline myopathy","termid":"MONDO:0015738"},{"relation_name":"is_a","term_name":"TPM2-related myopathy","termid":"MONDO:0100196"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0002320","MONDO:0005336"],"is_obsolete":false,"name":"congenital myopathy 23","secondary_identifiers":["GARD:15454","UMLS:C1836447","DOID:0110932","OMIM:609285","MEDGEN:324513","MESH:C538351","NCIT:C164225"],"synonyms":[{"name":"CAPM2","type":"exact"},{"name":"NEM4","type":"exact"},{"name":"TPM2 nemaline myopathy","type":"exact"},{"name":"cap myopathy 2","type":"exact"},{"name":"nemaline myopathy 4","type":"exact"},{"name":"nemaline myopathy 4, autosomal dominant","type":"exact"},{"name":"nemaline myopathy caused by mutation in TPM2","type":"exact"},{"name":"nemaline myopathy type 4","type":"exact"}],"termid":"MONDO:0012240","xrefs":{"Monarch":{"xref_id":"0012240"}}}


id: PBO:0050161
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 3 pseudogene 17","termid":"PBO:0050161"}


id: PBO:0001800
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.3.1.20","termid":"PBO:0001800"}


id: SO:0000430
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The R segment of the three-prime long terminal repeat.","direct_ancestors":[{"relation_name":"is_a","term_name":"three_prime_LTR_component","termid":"SO:0000849"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"R_three_prime_LTR_region","synonyms":[{"name":"R 3' long terminal repeat region","type":"exact"},{"name":"R three prime LTR region","type":"exact"}],"termid":"SO:0000430"}


id: GO:0050941
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell differentiation","termid":"GO:0045596"},{"relation_name":"is_a","term_name":"negative regulation of developmental pigmentation","termid":"GO:0048086"},{"relation_name":"is_a","term_name":"regulation of pigment cell differentiation","termid":"GO:0050932"},{"relation_name":"negatively_regulates","term_name":"pigment cell differentiation","termid":"GO:0050931"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of pigment cell differentiation","synonyms":[{"name":"down regulation of pigment cell differentiation","type":"exact"},{"name":"down-regulation of pigment cell differentiation","type":"exact"},{"name":"downregulation of pigment cell differentiation","type":"exact"},{"name":"inhibition of pigment cell differentiation","type":"narrow"}],"termid":"GO:0050941"}


id: PBO:0059865
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myotubularin related protein 2","termid":"PBO:0059865"}


id: FYECO:0000200
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which peptone was added to the medium or assay buffer in excess. Peptone is a mixture of nutrients generated by proteolytic digestion of animal protein with pepsin and serves as a nitrogen and amino acid source in some culture media. Peptone is not normally added to S. pombe growth media.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ peptone","termid":"FYECO:0000200"}


id: GO:0035446
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.","definition_xrefs":["EC:6.3.1.13","PMID:12033919"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acid-ammonia (or amide) ligase activity","termid":"GO:0016880"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016874","GO:0003824"],"is_obsolete":false,"name":"cysteine-glucosaminylinositol ligase activity","secondary_identifiers":["MetaCyc:RXN1G-121","RHEA:26176"],"synonyms":[{"name":"L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase","type":"related"},{"name":"MshC ligase","type":"related"},{"name":"desacetylmycothiol synthase","type":"related"}],"termid":"GO:0035446"}


id: GO:0044326
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine.","definition_xrefs":["GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"dendritic spine","termid":"GO:0043197"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"dendritic spine neck","secondary_identifiers":["NIF_Subcellular:sao1642908940"],"synonyms":[{"name":"neck","type":"broad"},{"name":"pedicle","type":"related"},{"name":"spine neck","type":"broad"}],"termid":"GO:0044326"}


id: GO:0042593
data:
  {"annotated_genes":["SJAG_02444","SJAG_03081","SJAG_04026","SJAG_04495","SJAG_04334","SJAG_01754","SJAG_01699","SJAG_04312","SJAG_00472","SJAG_00574","SJAG_01254"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[116946,107219,106868,102209,109390,115914,106277,109896,94591],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010619"},{"annotations":[76515,70502],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0001678"}]},"cv_name":"biological_process","definition":"Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate homeostasis","termid":"GO:0033500"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00472":null,"SJAG_00574":null,"SJAG_01254":null,"SJAG_01699":null,"SJAG_01754":null,"SJAG_02444":null,"SJAG_03081":null,"SJAG_04026":null,"SJAG_04312":null,"SJAG_04334":null,"SJAG_04495":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glucose homeostasis","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0042593","terms_by_termid":{"GO:0001678":null,"GO:0010619":null}}


id: PBO:0040196
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"argininosuccinate synthetase 1 pseudogene 9","termid":"PBO:0040196"}


id: GO:0006127
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of transferring reducing equivalents from NADH in the cytosol into the mitochondria via glycerol-3-phosphate. Cytosolic glycerol-3-phosphate dehydrogenase uses NADH to convert dihydroxyacetone phosphate (DHAP) to glycerol-3-phosphate (G3P) in the cytosol; G3P then diffuses into the mitochondria where mitochondrial glycerol-3-phosphate dehydrogenase uses FAD to convert G3P back to DHAP; the electrons on the reduced FADH2 are then available for use in the electron transport chain, and DHAP returns to the cytosol to complete the cycle.","definition_xrefs":["PMID:16368075","GOC:sjm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"NADH metabolic process","termid":"GO:0006734"},{"relation_name":"is_a","term_name":"NAD+ metabolic process","termid":"GO:0019674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0055086","GO:0008150"],"is_obsolete":false,"name":"glycerol-3-phosphate shuttle","secondary_identifiers":["MetaCyc:PWY-6118"],"synonyms":[{"name":"glycerol phosphate shuttle","type":"exact"},{"name":"glycerophosphate shuttle","type":"exact"}],"termid":"GO:0006127"}


id: PBO:0027582
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_vacuole_during_nitrogen_starvation","termid":"PBO:0027582"}


id: MONDO:0035357
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hepatic vascular disorder","termid":"MONDO:0002405"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"portosinusoidal vascular disease","secondary_identifiers":["UMLS:C5680289","MEDGEN:1842183","GARD:22393","Orphanet:596937"],"synonyms":[{"name":"PSVD","type":"exact"}],"termid":"MONDO:0035357","xrefs":{"Monarch":{"xref_id":"0035357"}}}


id: PBO:0085157
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nucleotide binding alpha subunit of the heterotrimeric G protein; interacts with the receptor Gpr1p, has signaling role in response to nutrients; required for the recruitment of Ras-GTP at the plasma membrane and in the nucleus","termid":"PBO:0085157"}


id: PBO:0054480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1880","termid":"PBO:0054480"}


id: PBO:0029686
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_oxidation","termid":"PBO:0029686"}


id: MONDO:0011843
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the TCAP gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"qualitative or quantitative defects of telethonin","termid":"MONDO:0016192"},{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"},{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"hypertrophic cardiomyopathy 25","secondary_identifiers":["DOID:0110328","MESH:C564388","OMIM:607487","MEDGEN:895360","UMLS:C4225408"],"synonyms":[{"name":"CMH25","type":"exact"},{"name":"TCAP hypertrophic cardiomyopathy","type":"exact"},{"name":"Tcap hypertrophic cardiomyopathy","type":"exact"},{"name":"cardiomyopathy familial hypertrophic 25","type":"exact"},{"name":"cardiomyopathy, familial hypertrophic, 25","type":"related"},{"name":"cardiomyopathy, familial hypertrophic, type 25","type":"exact"},{"name":"cardiomyopathy, hypertrophic, 25","type":"exact"},{"name":"hypertrophic cardiomyopathy caused by mutation in TCAP","type":"exact"},{"name":"hypertrophic cardiomyopathy type 25","type":"exact"}],"termid":"MONDO:0011843","xrefs":{"Monarch":{"xref_id":"0011843"}}}


id: PBO:0029614
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-viable_stubby_vegetative_cell","termid":"PBO:0029614"}


id: GO:1902745
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of lamellipodium organization.","definition_xrefs":["GOC:als","GOC:TermGenie","PMID:16054028","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell projection organization","termid":"GO:0031346"},{"relation_name":"is_a","term_name":"regulation of lamellipodium organization","termid":"GO:1902743"},{"relation_name":"positively_regulates","term_name":"lamellipodium organization","termid":"GO:0097581"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of lamellipodium organization","synonyms":[{"name":"activation of lamellipodium organization","type":"narrow"},{"name":"up regulation of lamellipodium organization","type":"exact"},{"name":"up-regulation of lamellipodium organization","type":"exact"},{"name":"upregulation of lamellipodium organization","type":"exact"}],"termid":"GO:1902745"}


id: FYPO:0000857
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of euchromatin is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.","definition_xrefs":["GO:0016584","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal nucleosome positioning","termid":"FYPO:0000856"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001312","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"normal nucleosome positioning in euchromatin","synonyms":[{"name":"normal nucleosome occupancy in euchromatin","type":"related"},{"name":"normal nucleosome positioning in euchromatin during mitotic cell cycle","type":"related"},{"name":"normal nucleosome positioning in euchromatin during vegetative growth","type":"exact"},{"name":"normal nucleosome spacing in euchromatin","type":"exact"}],"termid":"FYPO:0000857"}


id: FYECO:0000390
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which torin1 was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ torin1","synonyms":[{"name":"Torin1","type":"exact"}],"termid":"FYECO:0000390"}


id: PBO:0028890
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_after_spore_germination,_without_cell_division,_with_swollen_elongated_germ_tube","termid":"PBO:0028890"}


id: PBO:0056199
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAGEA8 antisense RNA 1","termid":"PBO:0056199"}


id: FYPO:0000722
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acidic pH. Cells stop growing (and may die) at a pH that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitive to stress during vegetative growth","termid":"FYPO:0000304"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000139","FYPO:0000003","FYPO:0001985"],"is_obsolete":false,"name":"sensitive to acidity","synonyms":[{"name":"acid pH resistance: decreased","type":"related"},{"name":"decreased growth during cellular response to acidity","type":"exact"},{"name":"decreased growth on acidic medium","type":"related"},{"name":"decreased vegetative cell population growth during cellular response to acidity","type":"exact"},{"name":"hypersensitive to acidity","type":"exact"},{"name":"sensitive to acidity during mitotic cell cycle","type":"related"},{"name":"sensitive to acidity during vegetative growth","type":"exact"}],"termid":"FYPO:0000722"}


id: GO:1904136
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis.","definition_xrefs":["GO_REF:0000058","GOC:dph","GOC:TermGenie","PMID:24892953"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of convergent extension involved in gastrulation","termid":"GO:1904103"},{"relation_name":"regulates","term_name":"convergent extension involved in notochord morphogenesis","termid":"GO:1904126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of convergent extension involved in notochord morphogenesis","termid":"GO:1904136"}


id: MONDO:0016889
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chromosome 7p deletion is a chromosome abnormality that occurs when there is a missing copy of the genetic material located on the short arm (p) of chromosome 7. The severity of the condition and the signs and symptoms depend on the size and location of the deletion and which genes are involved. Features that often occur in people with chromosome 7p deletion include developmental delay, intellectual disability, behavioral problems, and distinctive facial features. Most cases are not inherited, but people can pass the deletion on to their children. Treatment is based on the signs and symptoms present in each person.","definition_xrefs":["GARD:0001346"],"direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of chromosome 7","termid":"MONDO:0016872"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial deletion of the short arm of chromosome 7","secondary_identifiers":["icd11.foundation:1523142467","MEDGEN:1826021","GARD:1346","Orphanet:261911","UMLS:C5679668"],"synonyms":[{"name":"7p deletion","type":"related"},{"name":"7p monosomy","type":"related"},{"name":"chromosome 7p deletion","type":"related"},{"name":"deletion 7p","type":"related"},{"name":"monosomy 7p","type":"related"},{"name":"partial deletion of chromosome 7p","type":"exact"},{"name":"partial deletion of the short arm of chromosome type 7","type":"exact"},{"name":"partial monosomy 7p","type":"related"},{"name":"partial monosomy of chromosome 7p","type":"exact"},{"name":"partial monosomy of the short arm of chromosome 7","type":"exact"}],"termid":"MONDO:0016889","xrefs":{"Monarch":{"xref_id":"0016889"}}}


id: SO:0000327
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The last base to be translated into protein. It does not include the stop codon.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"CDS_region","termid":"SO:0000851"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coding_end","synonyms":[{"name":"coding end","type":"exact"},{"name":"translation termination site","type":"exact"},{"name":"translation_end","type":"exact"}],"termid":"SO:0000327"}


id: PBO:0012863
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exosome subunit Csl4","termid":"PBO:0012863"}


id: GO:0002249
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process contributing to lymphocyte anergy, a state of functional inactivation.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tolerance induction","termid":"GO:0002507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"lymphocyte anergy","termid":"GO:0002249"}


id: PBO:0054266
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1651","termid":"PBO:0054266"}


id: MONDO:0016164
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Herpetiform pemphigus is a rare superficial pemphigus disease characterized by severe intractable pruritus with erythematous or urticarial plaques and vesicles organized in a herpetiform pattern. Mucosae are generally spared. Eosinophilia in peripheral blood and low titers of circulating autoantibodies are observed in many cases. Histologically, minimal or no apparent acantholysis is associated.","definition_xrefs":["Orphanet:208524"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pemphigus","termid":"MONDO:0006594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005093","MONDO:0005046"],"is_obsolete":false,"name":"herpetiform pemphigus","secondary_identifiers":["GARD:20406","MEDGEN:1655315","UMLS:C4749730"],"termid":"MONDO:0016164","xrefs":{"Monarch":{"xref_id":"0016164"}}}


id: GO:0071819
data:
  {"annotated_genes":["SJAG_03599","SJAG_00641","SJAG_03752","SJAG_00087"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[62186,88847,112128,114684],"is_not":false,"summary":null,"term":"GO:0071819"}]},"cv_name":"cellular_component","definition":"A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.","definition_xrefs":["PMID:19226466","PMID:20395473"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00087":null,"SJAG_00641":null,"SJAG_03599":null,"SJAG_03752":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005634","GO:0032991","GO:0005575"],"is_obsolete":false,"name":"DUBm complex","references_by_uniquename":{"GO_REF:0000104":null,"GO_REF:0000107":null},"synonyms":[{"name":"SAGA DUBm complex","type":"narrow"},{"name":"deubiquitinating module","type":"exact"},{"name":"deubiquitination module","type":"exact"}],"termid":"GO:0071819","terms_by_termid":{"GO:0071819":null}}


id: PBO:0060106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND6 pseudogene 7","termid":"PBO:0060106"}


id: PBO:0016556
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BAR adaptor protein, human endophilin-A2 ortholog, implicated in endocytosis","termid":"PBO:0016556"}


id: MONDO:0013477
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the NEXN gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hypertrophic cardiomyopathy","termid":"MONDO:0024573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"hypertrophic cardiomyopathy 20","secondary_identifiers":["MEDGEN:462617","OMIM:613876","DOID:0110326","UMLS:C3151267"],"synonyms":[{"name":"CMH20","type":"exact"},{"name":"NEXN hypertrophic cardiomyopathy","type":"exact"},{"name":"cardiomyopathy familial hypertrophic 20","type":"exact"},{"name":"cardiomyopathy, familial hypertrophic, 20","type":"related"},{"name":"cardiomyopathy, familial hypertrophic, type 20","type":"exact"},{"name":"cardiomyopathy, hypertrophic, 20","type":"exact"},{"name":"hypertrophic cardiomyopathy caused by mutation in NEXN","type":"exact"},{"name":"hypertrophic cardiomyopathy type 20","type":"exact"}],"termid":"MONDO:0013477","xrefs":{"Monarch":{"xref_id":"0013477"}}}


id: PBO:0088171
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Xanthine-guanine phosphoribosyl transferase; required for xanthine utilization and for optimal utilization of guanine","termid":"PBO:0088171"}


id: FYPO:0005345
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which mitotic sister chromatid separation begins during interphase of the cell cycle.","definition_xrefs":["PomBase:mah","PMID:9808627"],"direct_ancestors":[{"relation_name":"is_a","term_name":"premature mitotic sister chromatid separation","termid":"FYPO:0000416"},{"relation_name":"is_a","term_name":"mitotic sister chromatid separation in absence of mitotic spindle","termid":"FYPO:0007125"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000337"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"part_of","termid":"FYPO:0000631"},{"rel_name":"part_of","termid":"FYPO:0005447"},{"rel_name":"part_of","termid":"FYPO:0000641"},{"rel_name":"part_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"part_of","termid":"FYPO:0000337"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000631","FYPO:0000641","FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0000337"],"is_obsolete":false,"name":"mitotic sister chromatid separation during interphase","synonyms":[{"name":"advanced mitotic sister chromatid separation during interphase","type":"exact"},{"name":"chromosome separation during interphase during vegetative growth","type":"exact"},{"name":"mitotic chromosome separation during interphase","type":"exact"},{"name":"premature mitotic sister chromatid separation during interphase","type":"exact"},{"name":"premature sister chromatid separation during interphase of mitotic cell cycle","type":"related"},{"name":"sister chromatid separation during mitotic interphase","type":"exact"}],"termid":"FYPO:0005345"}


id: PBO:0043241
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"claudin 1","termid":"PBO:0043241"}


id: GO:0051862
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:cc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biological process involved in interaction with symbiont","termid":"GO:0051702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"translocation of molecules into symbiont","synonyms":[{"name":"transport of molecules into symbiont","type":"exact"}],"termid":"GO:0051862"}


id: GO:0052024
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by symbiont of hormone or growth regulator levels in host (obsolete GO:0052024)","synonyms":[{"name":"activation by symbiont of hormone or growth regulator levels in host","type":"narrow"},{"name":"positive modulation of hormone or growth regulator levels in host","type":"exact"},{"name":"positive regulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction","type":"broad"},{"name":"stimulation by symbiont of hormone or growth regulator levels in host","type":"narrow"},{"name":"up regulation by symbiont of hormone or growth regulator levels in host","type":"exact"},{"name":"up-regulation by symbiont of hormone or growth regulator levels in host","type":"exact"},{"name":"upregulation by symbiont of hormone or growth regulator levels in host","type":"exact"}],"termid":"GO:0052024"}


id: PBO:0053452
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 400","termid":"PBO:0053452"}


id: PBO:0048811
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein subunit beta 5","termid":"PBO:0048811"}


id: MONDO:0800142
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An immunodeficiency disease caused by a variation in MAPK8, the gene encoding c-Jun N-terminal kinase 1 (JNK1), that is characterized by chronic mucocutaneous candidiasis and a connective tissue disorder that clinically overlaps with Ehlers-Danlos syndrome (EDS).","definition_xrefs":["PMID:31784499"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"chronic mucocutaneous candidiasis and connective tissue disease due to JNK1 haploinsufficiency","synonyms":[{"name":"JNK1 haploinsufficiency (causing combination of chronic mucocutaneous candidiasis and connective tissue disease)","type":"exact"}],"termid":"MONDO:0800142","xrefs":{"Monarch":{"xref_id":"0800142"}}}


id: GO:0042765
data:
  {"annotated_genes":["SJAG_03292","SJAG_00846","SJAG_05278","SJAG_02776","SJAG_03672"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[71037,71238,74917,74919,75741],"is_not":false,"summary":null,"term":"GO:0042765"}]},"cv_name":"cellular_component","definition":"An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.","definition_xrefs":["GOC:jl","PMID:12802054","GOC:rb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"caspase complex","termid":"GO:0008303"},{"relation_name":"is_a","term_name":"membrane protein complex","termid":"GO:0098796"},{"relation_name":"is_a","term_name":"endoplasmic reticulum protein-containing complex","termid":"GO:0140534"},{"relation_name":"is_a","term_name":"transferase complex","termid":"GO:1990234"},{"relation_name":"part_of","term_name":"endoplasmic reticulum membrane","termid":"GO:0005789"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00846":null,"SJAG_02776":null,"SJAG_03292":null,"SJAG_03672":null,"SJAG_05278":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005783"},{"rel_name":"part_of","termid":"GO:0005789"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0005783","GO:0032991","GO:0005789"],"is_obsolete":false,"name":"GPI-anchor transamidase complex","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"GPIT complex","type":"exact"}],"termid":"GO:0042765","terms_by_termid":{"GO:0042765":null}}


id: GO:0008341
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).","definition_xrefs":["GOC:go_curators","GOC:jid"],"gene_count":0,"genotype_count":0,"name":"obsolete response to cocaine (sensu Insecta) (obsolete GO:0008341)","synonyms":[{"name":"response to cocaine (sensu Insecta)","type":"exact"}],"termid":"GO:0008341"}


id: MONDO:0004920
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"male reproductive system disorder","termid":"MONDO:0003150"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydrocele","secondary_identifiers":["MEDGEN:318568","ICD9:603.9","UMLS:C1720771","DOID:9912","ICD9:603.8","SCTID:55434001"],"termid":"MONDO:0004920","xrefs":{"Monarch":{"xref_id":"0004920"}}}


id: GO:1905170
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle.","definition_xrefs":["GOC:PARL","GOC:TermGenie","GO_REF:0000058","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein localization","termid":"GO:1903828"},{"relation_name":"is_a","term_name":"regulation of protein localization to phagocytic vesicle","termid":"GO:1905169"},{"relation_name":"negatively_regulates","term_name":"protein localization to phagocytic vesicle","termid":"GO:1905161"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of protein localization to phagocytic vesicle","synonyms":[{"name":"down regulation of protein localisation in phagocytic vesicle","type":"exact"},{"name":"down regulation of protein localisation to phagocytic vesicle","type":"exact"},{"name":"down regulation of protein localisation to phagosome","type":"exact"},{"name":"down regulation of protein localization in phagocytic vesicle","type":"exact"},{"name":"down regulation of protein localization to phagocytic vesicle","type":"exact"},{"name":"down regulation of protein recruitment to phagosome","type":"exact"},{"name":"down-regulation of protein localisation in phagocytic vesicle","type":"exact"},{"name":"down-regulation of protein localisation to phagocytic vesicle","type":"exact"},{"name":"down-regulation of protein localisation to phagosome","type":"exact"},{"name":"down-regulation of protein localization in phagocytic vesicle","type":"exact"},{"name":"down-regulation of protein localization to phagocytic vesicle","type":"exact"},{"name":"down-regulation of protein recruitment to phagosome","type":"exact"},{"name":"downregulation of protein localisation in phagocytic vesicle","type":"exact"},{"name":"downregulation of protein localisation to phagocytic vesicle","type":"exact"},{"name":"downregulation of protein localisation to phagosome","type":"exact"},{"name":"downregulation of protein localization in phagocytic vesicle","type":"exact"},{"name":"downregulation of protein localization to phagocytic vesicle","type":"exact"},{"name":"downregulation of protein recruitment to phagosome","type":"exact"},{"name":"inhibition of protein localisation in phagocytic vesicle","type":"narrow"},{"name":"inhibition of protein localisation to phagocytic vesicle","type":"narrow"},{"name":"inhibition of protein localisation to phagosome","type":"narrow"},{"name":"inhibition of protein localization in phagocytic vesicle","type":"narrow"},{"name":"inhibition of protein localization to phagocytic vesicle","type":"narrow"},{"name":"inhibition of protein recruitment to phagosome","type":"narrow"},{"name":"negative regulation of protein localisation in phagocytic vesicle","type":"exact"},{"name":"negative regulation of protein localisation to phagocytic vesicle","type":"exact"},{"name":"negative regulation of protein localisation to phagosome","type":"exact"},{"name":"negative regulation of protein localization in phagocytic vesicle","type":"exact"},{"name":"negative regulation of protein recruitment to phagosome","type":"exact"}],"termid":"GO:1905170"}


id: PBO:0071017
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 19","termid":"PBO:0071017"}


id: FYPO:0001510
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a cell is viable, cell shape is altered, and cell size remains normal, in the vegetative growth phase of the life cycle.","definition_xrefs":["PomBase:mah","PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vegetative cell, abnormal cell shape, normal cell size","termid":"FYPO:0001121"},{"relation_name":"is_a","term_name":"viable vegetative cell with normal cell size","termid":"FYPO:0002176"},{"relation_name":"is_a","term_name":"viable vegetative cell with abnormal cell shape","termid":"FYPO:0002197"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0000257"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001312","FYPO:0000257","FYPO:0000005","FYPO:0000004","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"viable vegetative cell, abnormal cell shape, normal cell size","synonyms":[{"name":"viable lumpy cell","type":"related"},{"name":"viable vegetative cell with abnormal cell shape and normal cell size","type":"related"},{"name":"viable vegetative cell, abnormal cell shape, normal cell length","type":"narrow"},{"name":"viable vegetative cell, abnormal cell shape, normal cell size during mitotic cell cycle","type":"related"},{"name":"viable, abnormal cell shape, normal cell size during vegetative growth","type":"exact"}],"termid":"FYPO:0001510"}


id: PBO:0083246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; gene expression induced by heat","termid":"PBO:0083246"}


id: MONDO:0025270
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acquired infection of non-human animals by organisms of the genus toxoplasma.","definition_xrefs":["MESH:D014124"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protozoan infections, animal","termid":"MONDO:0025114"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"toxoplasmosis, non-human animal","synonyms":[{"name":"Toxoplasmoses, animal","type":"related"},{"name":"animal Toxoplasmoses","type":"related"},{"name":"animal toxoplasmosis","type":"related"}],"termid":"MONDO:0025270","xrefs":{"Monarch":{"xref_id":"0025270"}}}


id: PBO:0061545
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5', 3'-nucleotidase, cytosolic","termid":"PBO:0061545"}


id: PBO:0062094
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily A member 44 pseudogene","termid":"PBO:0062094"}


id: GO:0033939
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.","definition_xrefs":["EC:3.2.1.131"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing O-glycosyl compounds","termid":"GO:0004553"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016798","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"xylan alpha-1,2-glucuronosidase activity","secondary_identifiers":["MetaCyc:3.2.1.131-RXN"],"synonyms":[{"name":"1,2-alpha-glucuronidase activity","type":"related"},{"name":"alpha-(1->2)-glucuronidase activity","type":"related"},{"name":"xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity","type":"related"}],"termid":"GO:0033939"}


id: PBO:0038973
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adenosine A2b receptor pseudogene 1","termid":"PBO:0038973"}


id: PBO:0086107
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for assembly of the cytochrome bc(1) complex; acts as a chaperone for Rip1p and facilitates its insertion into the complex at a late stage of assembly; localized to the mitochondrial matrix; null mutant exhibits a respiratory growth defect and reduced mitochondrial zinc levels, which is characteristic of mutations affecting bc(1) complex assembly; member of the LYR protein family; human LYRM7 is a functional ortholog","termid":"PBO:0086107"}


id: PBO:0077799
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"torsin family 2 member A","termid":"PBO:0077799"}


id: PBO:0039593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anoctamin 10","termid":"PBO:0039593"}


id: PBO:0052525
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kelch like family member 40","termid":"PBO:0052525"}


id: PBO:0113296
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Proteasome-binding protein; interacts physically with multiple subunits of the 20S proteasome and genetically with genes encoding 20S core particle and 19S regulatory particle subunits; specifically blocks all three proteasome active sites; exhibits boundary activity which inhibits the propagation of heterochromatic silencing; contains a PI31 proteasome regulator domain and sequence similarity with human PSMF1, a proteasome inhibitor; not an essential gene","termid":"PBO:0113296"}


id: PBO:0079122
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis specific 13","termid":"PBO:0079122"}


id: PBO:0060721
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit A9","termid":"PBO:0060721"}


id: PBO:0059065
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MOB family member 4, phocein","termid":"PBO:0059065"}


id: PBO:0031708
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormally_arrested_mitotic_cell_cycle_progression","termid":"PBO:0031708"}


id: GO:1901361
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.","definition_xrefs":["GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete organic cyclic compound catabolic process (obsolete GO:1901361)","synonyms":[{"name":"organic cyclic compound breakdown","type":"exact"},{"name":"organic cyclic compound catabolism","type":"exact"},{"name":"organic cyclic compound degradation","type":"exact"}],"termid":"GO:1901361"}


id: MONDO:0014467
data:
  {"annotated_genes":["SJAG_01190"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87243],"is_not":false,"summary":null,"term":"MONDO:0014467"}]},"cv_name":"mondo","definition":"Any Charcot-Marie-Tooth disease in which the cause of the disease is a mutation in the COX6A1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"},{"relation_name":"is_a","term_name":"autosomal recessive intermediate Charcot-Marie-Tooth disease","termid":"MONDO:0017058"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01190":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0004069","MONDO:0006025","MONDO:0005066","MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease recessive intermediate D","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5569027","DOID:0110203","OMIM:616039","GARD:17723","MEDGEN:1800450","Orphanet:435998"],"synonyms":[{"name":"CMTRID","type":"exact"},{"name":"COX6A1 Charcot-Marie-Tooth disease","type":"exact"},{"name":"Charcot-Marie-Tooth disease caused by mutation in COX6A1","type":"exact"},{"name":"Charcot-Marie-Tooth disease recessive intermediate type D","type":"exact"},{"name":"Charcot-Marie-Tooth disease, recessive Intermediate type D","type":"exact"},{"name":"Charcot-Marie-Tooth disease, recessive intermediate D","type":"related"},{"name":"RI-CMT type D","type":"exact"},{"name":"autosomal recessive intermediate Charcot-Marie-Tooth disease type D","type":"exact"}],"termid":"MONDO:0014467","terms_by_termid":{"MONDO:0014467":null},"xrefs":{"Monarch":{"xref_id":"0014467"}}}


id: GO:0140327
data:
  {"annotated_genes":["SJAG_01945","SJAG_03050","SJAG_01731","SJAG_02516","SJAG_05209","SJAG_02897"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[102697,105453],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015247"},{"annotations":[94790,98289],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140351"},{"annotations":[99837],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0180013"},{"annotations":[98291,94792],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140345"},{"annotations":[98293,99839,94794],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090555"},{"annotations":[99840,112885],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140346"}]},"cv_name":"molecular_function","definition":"Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.","definition_xrefs":["Wikipedia:Flippase","PMID:20043909","PMID:25284293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ATPase-coupled intramembrane lipid transporter activity","termid":"GO:0140326"}],"gene_count":6,"genes_by_uniquename":{"SJAG_01731":null,"SJAG_01945":null,"SJAG_02516":null,"SJAG_02897":null,"SJAG_03050":null,"SJAG_05209":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140303"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0140303"],"is_obsolete":false,"name":"flippase activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"flippase activity (exoplasmic to cytosolic leaflet)","type":"exact"}],"termid":"GO:0140327","terms_by_termid":{"GO:0015247":null,"GO:0090555":null,"GO:0140345":null,"GO:0140346":null,"GO:0140351":null,"GO:0180013":null}}


id: SO:0001691
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A restriction enzyme recognition site that, when cleaved, results in no overhangs.","definition_xrefs":["SO:ke","SBOL:jgquinn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"restriction_enzyme_recognition_site","termid":"SO:0001687"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"blunt_end_restriction_enzyme_cleavage_site","synonyms":[{"name":"blunt end restriction enzyme cleavage site","type":"exact"}],"termid":"SO:0001691"}


id: GO:1902531
data:
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assayed or wild type"}]}]},"man1delta":{"display_name":"man1delta","display_uniquename":"man1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03449:allele-1","expression":"Null"}]}]},"mid1delta":{"display_name":"mid1delta","display_uniquename":"mid1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]}]},"mid1delta__pom1delta":{"display_name":"mid1delta pom1delta","display_uniquename":"mid1delta__pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]},"ned1-5A-S499A__S538A__T620A__T638A__S651A-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"ned1-5A(S499A; S538A; T620A; T638A; S651A 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type"}]}]},"ned1delta":{"display_name":"ned1delta","display_uniquename":"ned1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02763:allele-1","expression":"Null"}]}]},"nem1delta":{"display_name":"nem1delta","display_uniquename":"nem1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01906:allele-1","expression":"Null"}]}]},"nem2delta":{"display_name":"nem2delta","display_uniquename":"nem2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03940:allele-1","expression":"Null"}]}]},"nup132delta":{"display_name":"nup132delta","display_uniquename":"nup132delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01374:allele-1","expression":"Null"}]}]},"nup61delta":{"display_name":"nup61delta","display_uniquename":"nup61delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04284:allele-1","expression":"Null"}]}]},"pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"pim1-R152C(aa)","display_uniquename":"pim1-R152C-R152C-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04464:allele-1","expression":"Not assayed or wild type"}]}]},"pom1delta":{"display_name":"pom1delta","display_uniquename":"pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]},"rga4delta":{"display_name":"rga4delta","display_uniquename":"rga4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]}]},"rga4delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"rga4delta wee1-as8(T582G aa)","display_uniquename":"rga4delta__wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]},"shc1delta":{"display_name":"shc1delta","display_uniquename":"shc1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03360:allele-1","expression":"Null"}]}]},"sty1delta":{"display_name":"sty1delta","display_uniquename":"sty1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02592:allele-1","expression":"Null"}]}]},"vps32delta":{"display_name":"vps32delta","display_uniquename":"vps32delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01242:allele-1","expression":"Null"}]}]},"vps4delta":{"display_name":"vps4delta","display_uniquename":"vps4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_03892:allele-1","expression":"Null"}]}]},"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"wee1-as8(T582G aa)","display_uniquename":"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-2","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"multi_locus_annotated_genes":["SJAG_01143","SJAG_02392","SJAG_03596","SJAG_04280","SJAG_04522"],"name":"abnormal cellular component 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id: GO:0030841
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of intermediate filament polymerization","termid":"GO:0030839"},{"relation_name":"is_a","term_name":"positive regulation of protein polymerization","termid":"GO:0032273"},{"relation_name":"is_a","term_name":"positive regulation of cytoskeleton organization","termid":"GO:0051495"},{"relation_name":"positively_regulates","term_name":"intermediate filament polymerization","termid":"GO:0045107"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0007010"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"positively_regulates","termid":"GO:0065003"},{"rel_name":"regulates","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0007010","GO:0065003"],"is_obsolete":false,"name":"positive regulation of intermediate filament polymerization","synonyms":[{"name":"activation of intermediate filament polymerization","type":"narrow"},{"name":"positive regulation of intermediate filament polymerization and/or depolymerization","type":"broad"},{"name":"stimulation of intermediate filament polymerization","type":"narrow"},{"name":"up regulation of intermediate filament polymerization","type":"exact"},{"name":"up-regulation of intermediate filament polymerization","type":"exact"},{"name":"upregulation of intermediate filament polymerization","type":"exact"}],"termid":"GO:0030841"}


id: MONDO:0044245
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete nailbeds, pigmentation of (obsolete MONDO:0044245)","secondary_identifiers":["OMIM:161100"],"synonyms":[{"name":"NAILBEDS, pigmentation OF","type":"related"}],"termid":"MONDO:0044245","xrefs":{"Monarch":{"xref_id":"0044245"}}}


id: PBO:0028164
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_mycophenolic_acid","termid":"PBO:0028164"}


id: PR:O13945
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppk9 gene.","definition_xrefs":["UniProtKB:O13945","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein kinase domain-containing protein ppk9 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC23H4.02","synonyms":[{"name":"Spom972h-ppk9","type":"exact"}],"termid":"PR:O13945"}


id: PBO:0002172
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor TFIID complex subunit A/ SAGA complex subunit","termid":"PBO:0002172"}


id: GO:0035062
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).","definition_xrefs":["PMID:10984439","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear speck","termid":"GO:0016607"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"part_of","termid":"GO:0005654"}],"interesting_parent_ids":["GO:0005634","GO:0005654","GO:0005575"],"is_obsolete":false,"name":"omega speckle","termid":"GO:0035062"}


id: MONDO:0001920
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Otitis media that persists for at least six weeks, and that is associated with otorrhea through a perforated tympanic membrane.","definition_xrefs":["NCIT:C128386"],"direct_ancestors":[{"relation_name":"is_a","term_name":"suppurative otitis media","termid":"MONDO:0005975"},{"relation_name":"is_a","term_name":"chronic otitis media","termid":"MONDO:0021204"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chronic purulent otitis media","secondary_identifiers":["icd11.foundation:669695172","DOID:14247","ICD9:382.3","MEDGEN:543356","UMLS:C0271454","SCTID:38394007"],"synonyms":[{"name":"CSOM","type":"exact"},{"name":"chronic suppurative otitis Media","type":"exact"},{"name":"chronic suppurative otitis media","type":"exact"},{"name":"suppurative otitis media, chronic","type":"exact"}],"termid":"MONDO:0001920","xrefs":{"Monarch":{"xref_id":"0001920"}}}


id: PBO:0071132
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 134","termid":"PBO:0071132"}


id: PBO:0027557
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_transcription_from_RNA_polymerase_II_promoter","termid":"PBO:0027557"}


id: PBO:0090988
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rRNA processing protein Rrp36","termid":"PBO:0090988"}


id: PBO:0013803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"membrane-tethered transcription factor Sre2 (predicted)","termid":"PBO:0013803"}


id: GO:0048288
data:
  {"annotated_genes":["SJAG_00810"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79007],"is_not":false,"summary":null,"term":"GO:0048288"}]},"cv_name":"biological_process","definition":"The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear membrane fusion","termid":"GO:0000740"},{"relation_name":"part_of","term_name":"karyogamy","termid":"GO:0000741"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00810":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0061024"}],"interesting_parent_ids":["GO:0061024","GO:0008150"],"is_obsolete":false,"name":"nuclear membrane fusion involved in karyogamy","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"nuclear membrane fusion during karyogamy","type":"related"}],"termid":"GO:0048288","terms_by_termid":{"GO:0048288":null}}


id: PBO:0085740
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in transcription termination by RNA polymerase II; interacts with exonuclease Rat1p and Rai1p; has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition","termid":"PBO:0085740"}


id: PBO:0068461
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U1 small nuclear 38, pseudogene","termid":"PBO:0068461"}


id: PR:Q9UTB6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sds3 gene.","definition_xrefs":["UniProtKB:Q9UTB6","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptional regulatory protein sds3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC25B8.02","synonyms":[{"name":"Spom972h-sds3","type":"exact"},{"name":"clr6 histone deacetylase complex I subunit Sds3 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UTB6"}


id: MONDO:0020299
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete spinocerebellar ataxia type 15/16 (obsolete MONDO:0020299)","termid":"MONDO:0020299","xrefs":{"Monarch":{"xref_id":"0020299"}}}


id: MOD:00391
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-threonine residue to O-octanoyl-L-threonine.","definition_xrefs":["PubMed:11546772","Unimod:426#T","PubMed:12716131","RESID:AA0386"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-octanoylated residue","termid":"MOD:00669"},{"relation_name":"is_a","term_name":"O3-acylated L-threonine","termid":"MOD:02004"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:01155"}],"interesting_parent_ids":["MOD:01155"],"is_obsolete":false,"name":"O-octanoyl-L-threonine","synonyms":[{"name":"(2S)-2-amino-3-(octanoyloxy)butanoic acid","type":"exact"},{"name":"L-threonine octanoate ester","type":"exact"},{"name":"LIPID O-octanoyl threonine","type":"exact"},{"name":"O-octanoyl-L-threonine","type":"exact"},{"name":"O-octanoylated L-threonine","type":"exact"},{"name":"O3-octanoyl-L-threonine","type":"exact"},{"name":"OOctThr","type":"exact"},{"name":"Octanoyl","type":"related"},{"name":"octanoyl","type":"related"}],"termid":"MOD:00391"}


id: GO:0043435
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.","definition_xrefs":["PMID:15134857","Wikipedia:Corticotropin-releasing_hormone","PMID:11027914"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to peptide hormone","termid":"GO:0043434"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to corticotropin-releasing hormone","synonyms":[{"name":"response to CRF stimulus","type":"exact"},{"name":"response to CRH stimulus","type":"exact"},{"name":"response to corticoliberin stimulus","type":"exact"},{"name":"response to corticotropin-releasing factor stimulus","type":"exact"},{"name":"response to corticotropin-releasing hormone stimulus","type":"exact"}],"termid":"GO:0043435"}


id: FYPO_EXT:1000000
data:
  {"annotation_feature_type":"gene","cv_name":"fypo_extensions","definition":"root of FYPO extension ontology","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FYPO extension","termid":"FYPO_EXT:1000000"}


id: GO:0036514
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.","definition_xrefs":["GOC:PARL","PMID:21106844","GOC:bf","PMID:23517308"],"direct_ancestors":[{"relation_name":"is_a","term_name":"axon guidance","termid":"GO:0007411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dopaminergic neuron axon guidance","synonyms":[{"name":"DA axon guidance","type":"exact"},{"name":"dopaminergic axon guidance","type":"exact"},{"name":"mdDA axon guidance","type":"exact"}],"termid":"GO:0036514"}


id: GO:1905410
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cohesin unloading.","definition_xrefs":["PMID:26687354","GO_REF:0000058","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of mitotic cohesin unloading (obsolete GO:1905410)","termid":"GO:1905410"}


id: FYPO:0005664
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a cell is viable, and becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to nitrogen starvation.","definition_xrefs":["PMID:19366728","PMID:12399381","PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"viable cell","termid":"FYPO:0000124"},{"relation_name":"has_part","term_name":"elongated cell during nitrogen starvation","termid":"FYPO:0000998"},{"relation_name":"is_a","term_name":"viable cell","termid":"FYPO:0000124"},{"relation_name":"is_a","term_name":"elongated cell during nitrogen starvation","termid":"FYPO:0000998"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0000005"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0000004","FYPO:0000005"],"is_obsolete":false,"name":"viable elongated cell during nitrogen starvation","synonyms":[{"name":"cdr phenotype","type":"exact"},{"name":"viable elongated cell during nitrogen depletion","type":"exact"},{"name":"viable elongated cell during nitrogen deprivation","type":"exact"},{"name":"viable long cell during nitrogen starvation","type":"exact"}],"termid":"FYPO:0005664"}


id: GO:0008885
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.","definition_xrefs":["EC:6.3.1.8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acid-ammonia (or amide) ligase activity","termid":"GO:0016880"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016874"],"is_obsolete":false,"name":"glutathionylspermidine synthase activity","secondary_identifiers":["RHEA:21272","MetaCyc:GSPSYN-RXN"],"synonyms":[{"name":"GSP synthetase activity","type":"related"},{"name":"gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]","type":"related"},{"name":"gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity","type":"related"},{"name":"glutathione:spermidine ligase (ADP-forming) activity","type":"related"},{"name":"glutathionylspermidine synthetase activity","type":"related"}],"termid":"GO:0008885"}


id: PATO:0000674
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000674 absolute temperature value (obsolete PATO:0000674)","termid":"PATO:0000674"}


id: MONDO:0008935
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cerebellar ataxia-hypogonadism syndrome is a very rare autosomal recessive neurodegenerative disorder characterized by the combination of progressive cerebellar ataxia with onset from early childhood to the fourth decade, and hypogonadotropic hypogonadism (delayed puberty and lack of secondary sex characteristics). Cerebellar ataxia-hypogonadism syndrome belongs to a clinical continuum of neurodegenerative disorders along with clinically overlapping disorders such as ataxia-hypogonadism-choroidal dystrophy syndrome.","definition_xrefs":["Orphanet:1173"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary ataxia","termid":"MONDO:0100309"},{"relation_name":"is_a","term_name":"congenital hypogonadotropic hypogonadism","termid":"MONDO:0015770"},{"relation_name":"is_a","term_name":"inherited neurodegenerative disorder","termid":"MONDO:0024237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"cerebellar ataxia-hypogonadism syndrome","secondary_identifiers":["MEDGEN:349137","GARD:3314","DOID:0111587","OMIM:212840","UMLS:C1859305","MESH:C565870"],"synonyms":[{"name":"GDHS","type":"related"},{"name":"Gordon Holmes syndrome","type":"related"},{"name":"Gordon-Holmes syndrome","type":"exact"},{"name":"LHRH deficiency and ataxia","type":"related"},{"name":"cerebellar ataxia - hypogonadism","type":"related"},{"name":"cerebellar ataxia and hypogonadotropic hypogonadism","type":"related"},{"name":"luteinizing hormone releasing hormone, deficiency of with ataxia","type":"related"},{"name":"luteinizing hormone-releasing hormone deficiency with ataxia","type":"exact"},{"name":"luteinizing hormone-releasing hormone, deficiency of, with ataxia","type":"related"}],"termid":"MONDO:0008935","xrefs":{"Monarch":{"xref_id":"0008935"}}}


id: MONDO:0016832
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Distal 7q11.23 microduplication syndrome is a rare chromosomal anomaly characterized by a predominantly neuropsychiatric phenotype with a few dysmorphic characteristics. Speech delay, learning difficulties, attention deficit hyperactivity disorder, bipolar disorder and aggressiveness have been reported.","definition_xrefs":["Orphanet:261102"],"direct_ancestors":[{"relation_name":"is_a","term_name":"7q11.23 microduplication syndrome","termid":"MONDO:0012342"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"distal 7q11.23 microduplication syndrome","secondary_identifiers":["MEDGEN:1662568","UMLS:C4750782","GARD:20770"],"synonyms":[{"name":"Dup7q11.23D","type":"exact"},{"name":"distal dup(7)(q11.23)","type":"exact"},{"name":"distal trisomy 7q11.23","type":"exact"}],"termid":"MONDO:0016832","xrefs":{"Monarch":{"xref_id":"0016832"}}}


id: MONDO:0971033
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A thyroid gland carcinoma composed of groups of carcinoma cells with thymic epithelial differentiation.","definition_xrefs":["DOID:0081457"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thyroid gland carcinoma","termid":"MONDO:0015075"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"intrathyroid thymic carcinoma","secondary_identifiers":["MEDGEN:316474","UMLS:C1704613"],"termid":"MONDO:0971033","xrefs":{"Monarch":{"xref_id":"0971033"}}}


id: GO:0034265
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.","definition_xrefs":["PMID:18216168","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokinin biosynthetic process","termid":"GO:0009691"},{"relation_name":"is_a","term_name":"isopentenyl adenine metabolic process","termid":"GO:0034264"},{"relation_name":"is_a","term_name":"purine-containing compound biosynthetic process","termid":"GO:0072522"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"isopentenyl adenine biosynthetic process","synonyms":[{"name":"isopentenyl adenine anabolism","type":"exact"},{"name":"isopentenyl adenine biosynthesis","type":"exact"},{"name":"isopentenyl adenine formation","type":"exact"},{"name":"isopentenyl adenine synthesis","type":"exact"},{"name":"isopentenyladenine biosynthetic process","type":"exact"}],"termid":"GO:0034265"}


id: MONDO:0012427
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare autosomal dominant inherited disorder of connective tissue caused by mutations in either the TGFBR1 or TGFBR2 gene. Like Loeys-Dietz syndrome type I the disease is characterized by enlargement of the aorta and other arteries, and arterial tortuosity, but skeletal signs are typically less severe or absent in type 2. Skin abnormalities, such as velvety skin are often present in type 2.","definition_xrefs":["NCIT:C114768"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Loeys-Dietz syndrome","termid":"MONDO:0018954"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"Loeys-Dietz syndrome 2","secondary_identifiers":["MEDGEN:382398","UMLS:C2674574","GARD:10586","MESH:C537783","OMIM:610168","DOID:0070234"],"synonyms":[{"name":"LDS2","type":"related"},{"name":"Loeys-Dietz syndrome 2","type":"exact"},{"name":"Loeys-Dietz syndrome caused by mutation in TGFBR2","type":"exact"},{"name":"Loeys-Dietz syndrome type 2","type":"exact"},{"name":"Loeys-Dietz syndrome type II","type":"exact"},{"name":"Marfan syndrome, type II","type":"related"},{"name":"Marfan syndrome, type II, formerly","type":"related"},{"name":"TGFBR2 Loeys-Dietz syndrome","type":"exact"},{"name":"aortic aneurysm, familial thoracic 3","type":"related"}],"termid":"MONDO:0012427","xrefs":{"Monarch":{"xref_id":"0012427"}}}


id: MONDO:0018436
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13) is a rare subtype of acute myeloid leukemia with recurrent cytogenetic abnormalities characterized by clonal proliferation of myeloid blasts with predominantly megakaryoblastic differentiation in the bone marrow and blood, often with extensive infiltration of the abdominal organs. It occurs typically in infants and usually presents with hepatosplenomegaly, anemia, thrombocytopenia and nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections). Myelofibrosis and fibrosis of other infiltrated organs is also characteristic of this disease.","definition_xrefs":["Orphanet:402023"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute myeloid leukemia","termid":"MONDO:0018874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0004992","MONDO:0005046"],"is_obsolete":false,"name":"megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)","secondary_identifiers":["MEDGEN:1638466","UMLS:C4706584","GARD:21712","SCTID:763796007"],"synonyms":[{"name":"megakaryoblastic AML with t(1;22)(p13;q13)","type":"exact"}],"termid":"MONDO:0018436","xrefs":{"Monarch":{"xref_id":"0018436"}}}


id: MONDO:0013126
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Bartter syndrome, type 4B (obsolete MONDO:0013126)","termid":"MONDO:0013126","xrefs":{"Monarch":{"xref_id":"0013126"}}}


id: PBO:0067046
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 66, pseudogene","termid":"PBO:0067046"}


id: MONDO:0018909
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete legionellosis (obsolete MONDO:0018909)","termid":"MONDO:0018909","xrefs":{"Monarch":{"xref_id":"0018909"}}}


id: GO:0160177
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the rate which autophagosomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects).","definition_xrefs":["PMID:38360932"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of vesicle fusion","termid":"GO:0031340"},{"relation_name":"positively_regulates","term_name":"autophagosome-lysosome fusion","termid":"GO:0061909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0061024"},{"rel_name":"regulates","termid":"GO:0016192"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0016192","GO:0061024","GO:0006810"],"is_obsolete":false,"name":"positive regulation of autophagosome-lysosome fusion","termid":"GO:0160177"}


id: MONDO:0008636
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Double uterus, hemivagina and renal agenesis is a rare congenital urogenital anomaly characterized by the presence of double uterus (didelphys, bicornuate or septum-complete or partial), unilateral cervico-vaginal obstruction (obstructed hemivagina-communicant, not communicant or septate and unilateral cervical atresia) and ipsilateral renal anomalies (renal agenesis and/or other urinary tract anomalies). Patients are usually diagnosed at puberty after menarche due to recurrent severe dysmenorrhea, chronic pelvic pain, excessive foul smelling mucopurulent discharge, spotting and intermenstrual bleeding (depending on the existence of uterine or vaginal communications). fever, dyspareunia, and a palpable abdominal, pelvic or vaginal mass (mucocolpos or pyocolpos) may also be present.","definition_xrefs":["Orphanet:3411"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"reproductive system disorder","termid":"MONDO:0005039"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"double uterus-hemivagina-renal agenesis syndrome","secondary_identifiers":["MESH:C566010","OMIM:192050","SCTID:722431007","GARD:1910","UMLS:C1860549","MEDGEN:348132"],"synonyms":[{"name":"Double uterus and obstructed hemivagina syndrome","type":"exact"},{"name":"Herlyn-Werner syndrome","type":"exact"},{"name":"OHVIRA syndrome","type":"exact"},{"name":"Wunderlich syndrome","type":"exact"},{"name":"obstructed hemivagina and ipsilateral renal anomaly","type":"exact"},{"name":"uterus BICORNIS BICOLLIS with partial vaginal septum and unilateral HEMATOCOLPOS with ipsilateral renal agenesis","type":"related"}],"termid":"MONDO:0008636","xrefs":{"Monarch":{"xref_id":"0008636"}}}


id: MONDO:0016406
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete other metabolic disease with epilepsy (obsolete MONDO:0016406)","secondary_identifiers":["Orphanet:225713"],"termid":"MONDO:0016406","xrefs":{"Monarch":{"xref_id":"0016406"}}}


id: GO:0002369
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that contributes to cytokine production by a T cell.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cytokine production involved in immune response","termid":"GO:0002367"},{"relation_name":"is_a","term_name":"T cell mediated immunity","termid":"GO:0002456"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"T cell cytokine production","synonyms":[{"name":"T lymphocyte cytokine production","type":"exact"},{"name":"T-cell cytokine production","type":"exact"},{"name":"T-lymphocyte cytokine production","type":"exact"}],"termid":"GO:0002369"}


id: PBO:0000676
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5.4.2.1","termid":"PBO:0000676"}


id: GO:0032515
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops or reduces the activity of a phosphoprotein phosphatase.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of phosphoprotein phosphatase activity (obsolete GO:0032515)","synonyms":[{"name":"down regulation of calcineurin activity","type":"narrow"},{"name":"down regulation of phosphoprotein phosphatase activity","type":"exact"},{"name":"down regulation of protein phosphatase 2 activity","type":"related"},{"name":"down regulation of protein phosphatase 3 activity","type":"related"},{"name":"down regulation of protein phosphatase type 2A activity","type":"narrow"},{"name":"down regulation of protein phosphatase type 2B activity","type":"narrow"},{"name":"down-regulation of phosphoprotein phosphatase activity","type":"exact"},{"name":"down-regulation of protein phosphatase type 2A activity","type":"narrow"},{"name":"down-regulation of protein phosphatase type 2B activity","type":"narrow"},{"name":"downregulation of calcineurin activity","type":"narrow"},{"name":"downregulation of phosphoprotein phosphatase activity","type":"exact"},{"name":"downregulation of protein phosphatase 2 activity","type":"related"},{"name":"downregulation of protein phosphatase 3 activity","type":"related"},{"name":"downregulation of protein phosphatase type 2A activity","type":"narrow"},{"name":"downregulation of protein phosphatase type 2B activity","type":"narrow"},{"name":"inhibition of calcineurin activity","type":"narrow"},{"name":"inhibition of phosphoprotein phosphatase activity","type":"narrow"},{"name":"inhibition of protein phosphatase 2 activity","type":"related"},{"name":"inhibition of protein phosphatase 3 activity","type":"related"},{"name":"inhibition of protein phosphatase type 2A activity","type":"narrow"},{"name":"inhibition of protein phosphatase type 2B activity","type":"narrow"},{"name":"negative regulation of calcineurin activity","type":"narrow"},{"name":"negative regulation of protein phosphatase 2 activity","type":"related"},{"name":"negative regulation of protein phosphatase type 2A activity","type":"narrow"},{"name":"negative regulation of protein phosphatase type 2B activity","type":"narrow"},{"name":"regulation of protein phosphatase 3 activity","type":"related"}],"termid":"GO:0032515"}


id: GO:0035981
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.","definition_xrefs":["CL:0002673","GOC:yaf","PMID:3393851"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal muscle fiber differentiation","termid":"GO:0098528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tongue muscle cell differentiation","termid":"GO:0035981"}


id: MOD:01298
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification produced by formation of an adduct of an L-cysteine residue with 4-hydroxynonenal artificially reduced by a reagent such as NaBH4.","definition_xrefs":["PubMed:15133838","Unimod:335#C","PubMed:11910026"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"cysteine 4-hydroxynonenal adduct","termid":"MOD:01237"},{"relation_name":"is_a","term_name":"reduced 4-hydroxynonenal adduct","termid":"MOD:00642"},{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"},{"rel_name":"is_a","termid":"MOD:01155"}],"interesting_parent_ids":["MOD:00905","MOD:01155"],"is_obsolete":false,"name":"reduced cysteine 4-hydroxynonenal adduct","synonyms":[{"name":"HNE+Delta:H(2)","type":"related"},{"name":"reduced 4-Hydroxynonenal","type":"related"}],"termid":"MOD:01298"}


id: GO:0140568
data:
  {"annotated_genes":["SJAG_01435","SJAG_04203"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[101376],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140569"},{"annotations":[75087],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140570"}]},"cv_name":"biological_process","definition":"The removal of a mislocalized protein from a cellular membrane.","definition_xrefs":["PMID:24821790","PMID:28712723","PMID:32973005"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of protein localization to membrane","termid":"GO:0090150"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01435":null,"SJAG_04203":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"extraction of mislocalized protein from membrane","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0140568","terms_by_termid":{"GO:0140569":null,"GO:0140570":null}}


id: GO:0051135
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.","definition_xrefs":["PMID:12154375","PMID:9133426","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of alpha-beta T cell activation","termid":"GO:0046635"},{"relation_name":"is_a","term_name":"regulation of NK T cell activation","termid":"GO:0051133"},{"relation_name":"positively_regulates","term_name":"NK T cell activation","termid":"GO:0051132"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"positively_regulates","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"positive regulation of NK T cell activation","synonyms":[{"name":"activation of NK T cell activation","type":"narrow"},{"name":"positive regulation of NK T lymphocyte activation","type":"exact"},{"name":"positive regulation of NK T-cell activation","type":"exact"},{"name":"positive regulation of NK T-lymphocyte activation","type":"exact"},{"name":"positive regulation of NKT cell activation","type":"exact"},{"name":"positive regulation of NT cell activation","type":"exact"},{"name":"positive regulation of natural T cell activation","type":"exact"},{"name":"positive regulation of natural killer T cell activation","type":"exact"},{"name":"stimulation of NK T cell activation","type":"narrow"},{"name":"up regulation of NK T cell activation","type":"exact"},{"name":"up-regulation of NK T cell activation","type":"exact"},{"name":"upregulation of NK T cell activation","type":"exact"}],"termid":"GO:0051135"}


id: PBO:0086465
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative methyltransferase; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; not an essential gene; YMR310C has a paralog, YGR283C, that arose from the whole genome duplication","termid":"PBO:0086465"}


id: GO:0018194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of peptidyl-alanine.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-amino acid modification","termid":"GO:0018193"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-alanine modification","termid":"GO:0018194"}


id: MONDO:0001513
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disease of orbital part of eye adnexa","termid":"MONDO:0004751"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pulsating exophthalmos","secondary_identifiers":["UMLS:C0155271","DOID:12364","MEDGEN:509887","SCTID:2284002","icd11.foundation:1825207679","ICD9:376.35"],"termid":"MONDO:0001513","xrefs":{"Monarch":{"xref_id":"0001513"}}}


id: PBO:0075258
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 18 pseudogene 11","termid":"PBO:0075258"}


id: MONDO:0021289
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A in situ carcinoma that involves the caecum.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colon carcinoma in situ","termid":"MONDO:0004663"},{"relation_name":"is_a","term_name":"cecum carcinoma","termid":"MONDO:0006029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0004335"],"is_obsolete":false,"name":"carcinoma in situ of cecum","secondary_identifiers":["MEDGEN:83854","NCIT:C4594","SCTID:92559007","UMLS:C0347126"],"synonyms":[{"name":"caecum carcinoma in situ","type":"exact"},{"name":"caecum in situ carcinoma","type":"exact"},{"name":"carcinoma in situ of caecum","type":"exact"},{"name":"carcinoma in situ of the cecum","type":"exact"},{"name":"cecum carcinoma in situ","type":"exact"},{"name":"cecum carcinoma in situ aJCC v6","type":"exact"},{"name":"cecum carcinoma in situ aJCC v7","type":"exact"},{"name":"stage 0 caecum carcinoma","type":"exact"},{"name":"stage 0 cecum carcinoma","type":"exact"}],"termid":"MONDO:0021289","xrefs":{"Monarch":{"xref_id":"0021289"}}}


id: PBO:0076352
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"synaptotagmin 16","termid":"PBO:0076352"}


id: GO:1904708
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:19208546"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of epithelial cell apoptotic process","termid":"GO:1904035"},{"relation_name":"regulates","term_name":"granulosa cell apoptotic process","termid":"GO:1904700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of granulosa cell apoptotic process","synonyms":[{"name":"regulation of granulosa cell apoptosis","type":"narrow"},{"name":"regulation of granulosa cell of ovary apoptosis","type":"narrow"},{"name":"regulation of granulosa cell of ovary apoptotic process","type":"exact"}],"termid":"GO:1904708"}


id: MONDO:0016379
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Erosive pustular dermatosis of the scalp is a rare chronic inflammation of the scalp usually occurring in elderly women (>70 years old) and characterized by the development of painful pustules, shallow erosions, and crusting on atrophic skin that eventually result in cicatricial alopecia.","definition_xrefs":["Orphanet:222"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin disorder","termid":"MONDO:0005093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"erosive pustular dermatosis of the scalp","secondary_identifiers":["MEDGEN:96057","SCTID:238733003","GARD:2188","UMLS:C0406464","icd11.foundation:982719772"],"termid":"MONDO:0016379","xrefs":{"Monarch":{"xref_id":"0016379"}}}


id: FYPO:0006970
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of bisphosphoglyceric acid measured in the cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell during vegetative growth","termid":"FYPO:0001329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"decreased cellular bisphosphoglyceric acid level","synonyms":[{"name":"decreased cellular bisphosphoglyceric acid level during mitotic cell cycle","type":"related"},{"name":"decreased cellular bisphosphoglyceric acid level during vegetative growth","type":"exact"},{"name":"decreased cellular diphosphoglycerate level","type":"related"},{"name":"decreased level of bisphosphoglyceric acid in cell","type":"exact"},{"name":"reduced cellular bisphosphoglyceric acid level","type":"exact"}],"termid":"FYPO:0006970"}


id: GO:0010370
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A chromocenter adjacent to the nucleolus.","definition_xrefs":["PMID:15805479"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromocenter","termid":"GO:0010369"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"perinucleolar chromocenter","termid":"GO:0010370"}


id: PBO:0075455
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spermatogenesis associated 6","termid":"PBO:0075455"}


id: GO:0005726
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts.","definition_xrefs":["PMID:14731598"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"nuclear chromosome","termid":"GO:0000228"},{"relation_name":"part_of","term_name":"chromatin","termid":"GO:0000785"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"part_of","termid":"GO:0005634"}],"interesting_parent_ids":["GO:0005575","GO:0005694","GO:0005634"],"is_obsolete":false,"name":"perichromatin fibrils","termid":"GO:0005726"}


id: PBO:0116813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ENTPD3, EIF1B and MYRIP antisense RNA 1","termid":"PBO:0116813"}


id: FYPO:0000006
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is abnormal. A mitotic DNA damage checkpoint normally regulates progression through the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal response to DNA damage stimulus during vegetative growth","termid":"FYPO:0000157"},{"relation_name":"is_a","term_name":"abnormal mitotic DNA integrity checkpoint","termid":"FYPO:0000643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000298"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000298","FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0000631"],"is_obsolete":false,"name":"abnormal mitotic DNA damage checkpoint","synonyms":[{"name":"abnormal DNA damage checkpoint during mitotic cell cycle","type":"exact"},{"name":"abnormal mitotic DNA damage checkpoint activation","type":"exact"},{"name":"abnormal mitotic DNA damage checkpoint during cellular response to DNA damage","type":"exact"},{"name":"abnormal mitotic DNA damage checkpoint during vegetative growth","type":"exact"},{"name":"mitotic DNA damage checkpoint defects","type":"exact"}],"termid":"FYPO:0000006"}


id: PBO:0031201
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normally_arrested_mitotic_cell_cycle_progression","termid":"PBO:0031201"}


id: PBO:0006168
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-happens_during","termid":"PBO:0006168"}


id: GO:0031162
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The incorporation of exogenous sulfur into a metallo-sulfur cluster.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete sulfur incorporation into metallo-sulfur cluster (obsolete GO:0031162)","synonyms":[{"name":"sulphur incorporation into metallo-sulphur cluster","type":"exact"}],"termid":"GO:0031162"}


id: PBO:0043916
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collapsin response mediator protein 1","termid":"PBO:0043916"}


id: MONDO:0100221
data:
  {"annotated_genes":["SJAG_02326","SJAG_01307"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86229,86230],"is_not":false,"summary":null,"term":"MONDO:0100221"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"IFAP syndrome","termid":"MONDO:0100212"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01307":null,"SJAG_02326":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"IFAP syndrome 2","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16402","OMIM:619016","MEDGEN:1763502","UMLS:C5436607"],"synonyms":[{"name":"IFAP SYNDROME 2","type":"exact"},{"name":"IFAP2","type":"exact"},{"name":"ichthyosis , follicular, with atrichia and photophobia syndrome 2","type":"exact"},{"name":"ichthyosis follicularis, atrichia, and photophobia syndrome 2","type":"exact"}],"termid":"MONDO:0100221","terms_by_termid":{"MONDO:0100221":null},"xrefs":{"Monarch":{"xref_id":"0100221"}}}


id: GO:2000538
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of lymphocyte chemotaxis","termid":"GO:0140131"},{"relation_name":"is_a","term_name":"regulation of B cell chemotaxis","termid":"GO:2000537"},{"relation_name":"positively_regulates","term_name":"B cell chemotaxis","termid":"GO:0035754"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of B cell chemotaxis","termid":"GO:2000538"}


id: PBO:0076896
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed 50","termid":"PBO:0076896"}


id: MONDO:1011359
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Subcutaneous tissue disorder that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"integumentary system disorder, non-human animal","termid":"MONDO:1011328"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"subcutaneous tissue disorder, non-human animal","termid":"MONDO:1011359","xrefs":{"Monarch":{"xref_id":"1011359"}}}


id: FYPO:0000063
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which DNA recombination is abnormal. DNA recombination is a process that results in reassortment of genes, producing gene combinations different from those that were present in the parents.","definition_xrefs":["PomBase:mah","GO:0006310"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA metabolism phenotype","termid":"FYPO:0000293"},{"relation_name":"is_a","term_name":"abnormal metabolic process","termid":"FYPO:0000860"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0000293"],"is_obsolete":false,"name":"abnormal DNA recombination","synonyms":[{"name":"abnormal recombination","type":"exact"},{"name":"recombination defects","type":"exact"}],"termid":"FYPO:0000063"}


id: GO:0071005
data:
  {"annotated_genes":["SJAG_03430"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[105998],"is_not":false,"summary":null,"term":"GO:0071005"}]},"cv_name":"cellular_component","definition":"A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.","definition_xrefs":["GOC:krc","GOC:ab","PMID:18322460","GOC:mah","PMID:19239890"],"direct_ancestors":[{"relation_name":"is_a","term_name":"U2-type spliceosomal complex","termid":"GO:0005684"},{"relation_name":"is_a","term_name":"precatalytic spliceosome","termid":"GO:0071011"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03430":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005634","GO:0032991"],"is_obsolete":false,"name":"U2-type precatalytic spliceosome","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"GT-AG precatalytic spliceosome","type":"narrow"},{"name":"major precatalytic spliceosome","type":"exact"},{"name":"mammalian U2-type spliceosomal complex B","type":"narrow"},{"name":"mammalian U2-type spliceosomal complex B1","type":"narrow"},{"name":"yeast U12-type spliceosomal complex A2-1","type":"related"}],"termid":"GO:0071005","terms_by_termid":{"GO:0071005":null}}


id: PBO:0036467
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial DNA branch migration helicase Irc3 (predicted)","termid":"PBO:0036467"}


id: PBO:0068627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4 small nuclear 7, pseudogene","termid":"PBO:0068627"}


id: MONDO:0011260
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of pancreas lymphoma that is caused by an inherited modification of the individual's genome.","definition_xrefs":["MONDO:patterns/hereditary"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreas lymphoma","termid":"MONDO:0002114"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005570","MONDO:0004335"],"is_obsolete":false,"name":"pancreatic lymphoma, familial","secondary_identifiers":["MESH:C566516","OMIM:602596","MEDGEN:355383","UMLS:C1865139"],"synonyms":[{"name":"hereditary pancreas lymphoma","type":"exact"},{"name":"pancreatic lymphoma, familial","type":"exact"}],"termid":"MONDO:0011260","xrefs":{"Monarch":{"xref_id":"0011260"}}}


id: MONDO:0007783
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any malignant hyperthermia of anesthesia in which the cause of the disease is a mutation in the RYR1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"malignant hyperthermia of anesthesia","termid":"MONDO:0018493"},{"relation_name":"is_a","term_name":"malignant hyperthermia, susceptibility to","termid":"MONDO:0800188"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malignant hyperthermia, susceptibility to, 1","secondary_identifiers":["MESH:C535694","DOID:0080990","OMIM:145600","UMLS:C2930980","MEDGEN:443948"],"synonyms":[{"name":"King syndrome","type":"related"},{"name":"King-Denborough syndrome","type":"related"},{"name":"King-Denborough syndrome, included","type":"related"},{"name":"MHS","type":"related"},{"name":"MHS1","type":"related"},{"name":"RYR1 malignant hyperthermia of anaesthesia","type":"exact"},{"name":"RYR1 malignant hyperthermia of anesthesia","type":"exact"},{"name":"hyperpyrexia, malignant","type":"related"},{"name":"hyperpyrexia, malignant;MH KING syndrome, included","type":"related"},{"name":"hyperthermia of anaesthesia","type":"related"},{"name":"hyperthermia of anesthesia","type":"related"},{"name":"malignant hyperthermia of anaesthesia caused by mutation in RYR1","type":"exact"},{"name":"malignant hyperthermia of anesthesia caused by mutation in RYR1","type":"exact"},{"name":"malignant hyperthermia susceptibility 1","type":"exact"},{"name":"malignant hyperthermia susceptibility type 1","type":"related"},{"name":"malignant hyperthermia, susceptibility to, 1","type":"exact"},{"name":"malignant hyperthermia, susceptibility to, type 1","type":"exact"},{"name":"susceptibility to malignant hyperthermia 1","type":"related"}],"termid":"MONDO:0007783","xrefs":{"Monarch":{"xref_id":"0007783"}}}


id: GO:1905687
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity.","definition_xrefs":["GO_REF:0000059","GOC:PARL","GOC:TermGenie","PMID:23091060","GOC:bc"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of diacylglycerol kinase activity (obsolete GO:1905687)","synonyms":[{"name":"regulation of 1,2-diacylglycerol kinase (phosphorylating)","type":"exact"},{"name":"regulation of 1,2-diacylglycerol kinase activity","type":"exact"},{"name":"regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity","type":"narrow"},{"name":"regulation of ATP:diacylglycerol phosphotransferase activity","type":"narrow"},{"name":"regulation of CTP:diacylglycerol kinase activity","type":"narrow"},{"name":"regulation of DG kinase activity","type":"exact"},{"name":"regulation of DGK activity","type":"exact"},{"name":"regulation of arachidonoyl-specific diacylglycerol kinase activity","type":"exact"},{"name":"regulation of diacylglycerol:ATP kinase activity","type":"narrow"},{"name":"regulation of diglyceride kinase activity","type":"exact"},{"name":"regulation of sn-1,2-diacylglycerol kinase activity","type":"exact"}],"termid":"GO:1905687"}


id: PBO:0047243
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 236 member C","termid":"PBO:0047243"}


id: PBO:0002061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH dehydrogenase (predicted)","termid":"PBO:0002061"}


id: PATO:0001857
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape quality in a bearer by virtue of the bearer's curving inward.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"concavity","termid":"PATO:0002005"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"concave","termid":"PATO:0001857"}


id: PR:O43040
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ctf1 gene.","definition_xrefs":["UniProtKB:O43040","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cleavage and termination factor 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC3B9.11c","synonyms":[{"name":"Spom972h-ctf1","type":"exact"},{"name":"transcription termination factor ctf1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O43040"}


id: PBO:0072069
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S11 pseudogene 7","termid":"PBO:0072069"}


id: PBO:0039262
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aldehyde dehydrogenase 7 family member A1 pseudogene 4","termid":"PBO:0039262"}


id: PBO:0054402
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1798","termid":"PBO:0054402"}


id: FYPO:0000879
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal histone H3-K9 trimethylation during vegetative growth","termid":"FYPO:0000787"},{"relation_name":"is_a","term_name":"increased histone H3-K9 methylation during vegetative growth","termid":"FYPO:0000871"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002494","FYPO:0002274","FYPO:0001985","FYPO:0001320","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"increased histone H3-K9 trimethylation during vegetative growth","synonyms":[{"name":"increased histone H3 K9 trimethylation during vegetative growth","type":"exact"},{"name":"increased histone H3-K9 trimethylation during mitotic cell cycle","type":"related"},{"name":"increased histone H3K9 trimethylation during vegetative growth","type":"exact"},{"name":"increased histone H3K9me3 during vegetative growth","type":"exact"},{"name":"increased histone lysine H3 K9 trimethylation during vegetative growth","type":"exact"}],"termid":"FYPO:0000879"}


id: PBO:0071512
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L34 pseudogene 15","termid":"PBO:0071512"}


id: GO:0043600
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins.","definition_xrefs":["GOC:mtg_sensu","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"replisome","termid":"GO:0030894"},{"relation_name":"part_of","term_name":"cytoplasmic replication fork","termid":"GO:0043597"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005694"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0005575","GO:0005694"],"is_obsolete":false,"name":"cytoplasmic replisome","synonyms":[{"name":"prokaryotic replisome","type":"exact"}],"termid":"GO:0043600"}


id: PBO:0061437
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor subfamily 2 group C member 2","termid":"PBO:0061437"}


id: PR:Q9UUI4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A glioma tumor suppressor candidate region gene 2 protein that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01992","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C22F8.09 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22F8.09","secondary_identifiers":["UniProtKB:Q9UUI4"],"synonyms":[{"name":"Spom972h-GLTSCR2","type":"exact"}],"termid":"PR:Q9UUI4"}


id: PBO:0051754
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inositol hexakisphosphate kinase 3","termid":"PBO:0051754"}


id: GO:0060688
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of anatomical structure morphogenesis","termid":"GO:0022603"},{"relation_name":"is_a","term_name":"regulation of multicellular organismal process","termid":"GO:0051239"},{"relation_name":"regulates","term_name":"morphogenesis of a branching structure","termid":"GO:0001763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of morphogenesis of a branching structure","termid":"GO:0060688"}


id: GO:0044678
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine.","definition_xrefs":["PMID:8174566","GOC:mengo_curators","PMID:8119281","PMID:9063468"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase complex","termid":"GO:1990204"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"CoB-CoM heterodisulfide reductase complex","synonyms":[{"name":"coenzyme M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase complex","type":"exact"},{"name":"hydrogen:coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide oxidoreductase complex","type":"exact"}],"termid":"GO:0044678"}


id: MONDO:0011478
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"growth and developintellectual disability, ocular ptosis, cardiac defect, and anal atresia","secondary_identifiers":["MESH:C565755","UMLS:C1858182","MEDGEN:346757","OMIM:604690"],"synonyms":[{"name":"Roca syndrome","type":"related"},{"name":"Roca-Weidemann syndrome","type":"related"},{"name":"growth and developintellectual disability, ocular ptosis, cardiac defect, and anal atresia","type":"exact"},{"name":"growth and developmental retardation, ocular ptosis, cardiac defect, and anal atresia","type":"exact"}],"termid":"MONDO:0011478","xrefs":{"Monarch":{"xref_id":"0011478"}}}


id: PBO:0046480
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ERCC excision repair 5, endonuclease","termid":"PBO:0046480"}


id: GO:1903381
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","GOC:bf","GOC:PARL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of neuron apoptotic process","termid":"GO:0043523"},{"relation_name":"is_a","term_name":"regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","termid":"GO:1902235"},{"relation_name":"regulates","term_name":"neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","termid":"GO:0036483"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway","synonyms":[{"name":"regulation of ER stress-induced neuron apoptosis","type":"broad"},{"name":"regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway","type":"exact"},{"name":"regulation of endoplasmic reticulum stress-induced neuron apoptosis","type":"broad"},{"name":"regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","type":"exact"}],"termid":"GO:1903381"}


id: PBO:0074072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 25 member 47","termid":"PBO:0074072"}


id: GO:0043531
data:
  {"annotated_genes":["SJAG_02598","SJAG_02564","SJAG_02785","SJAG_03660"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70391,73160,89579,93220],"is_not":false,"summary":null,"term":"GO:0043531"}]},"cv_name":"molecular_function","definition":"Binding to ADP, adenosine 5'-diphosphate.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"adenyl ribonucleotide binding","termid":"GO:0032559"},{"relation_name":"is_a","term_name":"anion binding","termid":"GO:0043168"}],"gene_count":4,"genes_by_uniquename":{"SJAG_02564":null,"SJAG_02598":null,"SJAG_02785":null,"SJAG_03660":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"ADP binding","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"adenosine 5'-diphosphate binding","type":"exact"},{"name":"adenosine diphosphate binding","type":"exact"}],"termid":"GO:0043531","terms_by_termid":{"GO:0043531":null}}


id: PBO:0090571
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial outer membrane ATPase Msp1/Yta4","termid":"PBO:0090571"}


id: GO:0032015
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of Ran protein signal transduction.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of Ran protein signal transduction (obsolete GO:0032015)","termid":"GO:0032015"}


id: GO:0000821
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amino acid metabolic process","termid":"GO:0006521"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"arginine metabolic process","termid":"GO:0006525"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0006520","GO:0044281"],"is_obsolete":false,"name":"regulation of arginine metabolic process","synonyms":[{"name":"regulation of arginine metabolism","type":"exact"}],"termid":"GO:0000821"}


id: PBO:0059627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MTCH1 pseudogene 2","termid":"PBO:0059627"}


id: GO:1990524
data:
  {"annotated_genes":["SJAG_07008"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[110102],"is_not":false,"summary":null,"term":"GO:1990524"}]},"cv_name":"cellular_component","definition":"A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p.","definition_xrefs":["GOC:rn","PMID:24942160"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inner mitochondrial membrane protein complex","termid":"GO:0098800"}],"gene_count":1,"genes_by_uniquename":{"SJAG_07008":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005739"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737","GO:0005739","GO:0032991"],"is_obsolete":false,"name":"INA complex","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"INAC","type":"exact"}],"termid":"GO:1990524","terms_by_termid":{"GO:1990524":null}}


id: GO:0046579
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of Ras protein signal transduction","termid":"GO:0046578"},{"relation_name":"is_a","term_name":"positive regulation of small GTPase mediated signal transduction","termid":"GO:0051057"},{"relation_name":"positively_regulates","term_name":"Ras protein signal transduction","termid":"GO:0007265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of Ras protein signal transduction","secondary_identifiers":["Reactome:R-HSA-9026519","Reactome:R-HSA-9027284","Reactome:R-HSA-9034864"],"synonyms":[{"name":"activation of Ras protein signal transduction","type":"narrow"},{"name":"stimulation of Ras protein signal transduction","type":"narrow"},{"name":"up regulation of Ras protein signal transduction","type":"exact"},{"name":"up-regulation of Ras protein signal transduction","type":"exact"},{"name":"upregulation of Ras protein signal transduction","type":"exact"}],"termid":"GO:0046579"}


id: GO:0033595
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to hydroxyisoflavone","termid":"GO:0033594"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to genistein","termid":"GO:0033595"}


id: GO:0000736
data:
  {"annotated_genes":["SJAG_02556"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75338],"is_not":false,"summary":null,"term":"GO:0000736"}]},"cv_name":"biological_process","definition":"During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.","definition_xrefs":["PMID:10357855"],"direct_ancestors":[{"relation_name":"is_a","term_name":"removal of nonhomologous ends","termid":"GO:0000735"},{"relation_name":"part_of","term_name":"double-strand break repair via single-strand annealing","termid":"GO:0045002"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02556":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006281","GO:0006259","GO:0008150"],"is_obsolete":false,"name":"double-strand break repair via single-strand annealing, removal of nonhomologous ends","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0000736","terms_by_termid":{"GO:0000736":null}}


id: MONDO:0004771
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Fuchs' heterochromic uveitis (obsolete MONDO:0004771)","termid":"MONDO:0004771","xrefs":{"Monarch":{"xref_id":"0004771"}}}


id: GO:0015736
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.","definition_xrefs":["GOC:ai","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uronic acid transmembrane transport","termid":"GO:0015735"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"hexuronate transmembrane transport","synonyms":[{"name":"hexuronate transport","type":"related"}],"termid":"GO:0015736"}


id: PBO:0073501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small glutamine rich tetratricopeptide repeat co-chaperone beta","termid":"PBO:0073501"}


id: GO:0004471
data:
  {"annotated_genes":["SJAG_02176"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73585],"is_not":false,"summary":null,"term":"GO:0004471"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH.","definition_xrefs":["RHEA:12653"],"direct_ancestors":[{"relation_name":"is_a","term_name":"malic enzyme activity","termid":"GO:0004470"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02176":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"malate dehydrogenase (decarboxylating) (NAD+) activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["GO:0004472","GO:0016619","KEGG_REACTION:R00214","EC:1.1.1.39","Reactome:R-HSA-9012268","MetaCyc:1.1.1.39-RXN"],"synonyms":[{"name":"'malic' enzyme","type":"related"},{"name":"(S)-malate:NAD+ oxidoreductase (decarboxylating)","type":"related"},{"name":"(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)","type":"related"},{"name":"NAD-linked malic enzyme","type":"related"},{"name":"NAD-malic enzyme activity","type":"broad"},{"name":"NAD-specific malic enzyme","type":"related"},{"name":"malate dehydrogenase (decarboxylating) activity","type":"related"},{"name":"malate dehydrogenase (oxaloacetate-decarboxylating) activity","type":"exact"}],"termid":"GO:0004471","terms_by_termid":{"GO:0004471":null}}


id: PBO:0047578
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FGFR1 oncogene partner 2 pseudogene 1","termid":"PBO:0047578"}


id: PBO:0076550
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TatD DNase domain containing 2 pseudogene 2","termid":"PBO:0076550"}


id: GO:0042796
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.","definition_xrefs":["GOC:jl","ISBN:0321000382"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription by RNA polymerase III","termid":"GO:0006383"},{"relation_name":"is_a","term_name":"snRNA transcription","termid":"GO:0009301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0016073"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0016073","GO:0006351","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"snRNA transcription by RNA polymerase III","synonyms":[{"name":"snRNA transcription from Pol III promoter","type":"exact"},{"name":"snRNA transcription from RNA polymerase III promoter","type":"exact"}],"termid":"GO:0042796"}


id: GO:0015506
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).","definition_xrefs":["TC:2.A.41.1.1","TC:2.A.1.10.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside transmembrane transporter activity","termid":"GO:0005337"},{"relation_name":"is_a","term_name":"solute:proton symporter activity","termid":"GO:0015295"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"nucleoside:proton symporter activity","secondary_identifiers":["GO:0015536"],"synonyms":[{"name":"nucleoside permease activity","type":"related"},{"name":"nucleoside:hydrogen ion symporter activity","type":"exact"},{"name":"nucleoside:hydrogen symporter activity","type":"exact"}],"termid":"GO:0015506"}


id: GO:0061221
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney mesenchyme morphogenesis","termid":"GO:0072131"},{"relation_name":"part_of","term_name":"mesonephric mesenchyme development","termid":"GO:0061219"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric mesenchyme morphogenesis","termid":"GO:0061221"}


id: FYECO:0000431
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which itraconazole was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ itraconazole","synonyms":[{"name":"+ itraconazole","type":"exact"}],"termid":"FYECO:0000431"}


id: PBO:0038847
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADAM metallopeptidase with thrombospondin type 1 motif 16","termid":"PBO:0038847"}


id: PBO:0068663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4 small nuclear 44, pseudogene","termid":"PBO:0068663"}


id: GO:0008226
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled amine receptor activity","termid":"GO:0008227"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"tyramine receptor activity","termid":"GO:0008226"}


id: PBO:0073824
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 7 member 3","termid":"PBO:0073824"}


id: GO:0071125
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.","definition_xrefs":["PMID:15834425"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005886"],"is_obsolete":false,"name":"alphaV-beta3 integrin-EGFR complex","synonyms":[{"name":"ITGAV-ITGB3-EGFR complex","type":"narrow"}],"termid":"GO:0071125"}


id: GO:0033030
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.","definition_xrefs":["GOC:add","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of neutrophil apoptotic process","termid":"GO:0033029"},{"relation_name":"is_a","term_name":"negative regulation of myeloid cell apoptotic process","termid":"GO:0033033"},{"relation_name":"is_a","term_name":"negative regulation of leukocyte apoptotic process","termid":"GO:2000107"},{"relation_name":"negatively_regulates","term_name":"neutrophil apoptotic process","termid":"GO:0001781"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of neutrophil apoptotic process","synonyms":[{"name":"down regulation of neutrophil apoptosis","type":"exact"},{"name":"down-regulation of neutrophil apoptosis","type":"exact"},{"name":"downregulation of neutrophil apoptosis","type":"exact"},{"name":"inhibition of neutrophil apoptosis","type":"narrow"},{"name":"negative regulation of neutrophil apoptosis","type":"narrow"}],"termid":"GO:0033030"}


id: PBO:0046273
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"emerin","termid":"PBO:0046273"}


id: PBO:0051920
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"integrin subunit beta 3 binding protein","termid":"PBO:0051920"}


id: GO:0015040
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway.","definition_xrefs":["PMID:8599534"],"gene_count":0,"genotype_count":0,"name":"obsolete electron transfer flavoprotein, group I (obsolete GO:0015040)","synonyms":[{"name":"electron transfer flavoprotein, group I","type":"exact"}],"termid":"GO:0015040"}


id: PBO:0074784
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 5","termid":"PBO:0074784"}


id: MONDO:0000809
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by disseminated intravascular coagulation.","definition_xrefs":["MESH:D055665"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disseminated intravascular coagulation","termid":"MONDO:0001243"},{"relation_name":"is_a","term_name":"purpura","termid":"MONDO:0002610"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"purpura fulminans","secondary_identifiers":["icd11.foundation:1293848111","SCTID:13507004","UMLS:C0085650","DOID:0060538","MEDGEN:88448"],"synonyms":[{"name":"fibrinolytic purpura","type":"related"},{"name":"purpura gangrenosa","type":"exact"}],"termid":"MONDO:0000809","xrefs":{"Monarch":{"xref_id":"0000809"}}}


id: MONDO:1012201
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondroma causing progressive posterior paresis, non-human animal","termid":"MONDO:1011950"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteochondroma causing progressive posterior paresis, dog","secondary_identifiers":["OMIA:000749-9615"],"termid":"MONDO:1012201","xrefs":{"Monarch":{"xref_id":"1012201"}}}


id: MONDO:0008325
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pseudoatrophoderma colli","secondary_identifiers":["MEDGEN:96061","UMLS:C0406561","OMIM:177350","MESH:C562909","SCTID:238840009"],"synonyms":[{"name":"Pseudoatrophoderma colli","type":"exact"}],"termid":"MONDO:0008325","xrefs":{"Monarch":{"xref_id":"0008325"}}}


id: MOD:00000
data:
  {"annotated_genes":["SJAG_02522","SJAG_02260","SJAG_02980","SJAG_00827","SJAG_04819","SJAG_00109","SJAG_03012","SJAG_03290","SJAG_02694","SJAG_01488","SJAG_04953","SJAG_01970","SJAG_02183","SJAG_00784","SJAG_00733","SJAG_03632","SJAG_01162","SJAG_00288","SJAG_00254","SJAG_02766","SJAG_00937","SJAG_00432","SJAG_04972","SJAG_02435","SJAG_00318","SJAG_04149","SJAG_00096","SJAG_02504","SJAG_03671","SJAG_03032","SJAG_03861","SJAG_02205","SJAG_04125","SJAG_04553","SJAG_01587","SJAG_02972","SJAG_01626","SJAG_02827","SJAG_00331","SJAG_02489","SJAG_03641","SJAG_04238","SJAG_03009","SJAG_02388","SJAG_01671","SJAG_05230","SJAG_00464","SJAG_02763","SJAG_04551","SJAG_03524","SJAG_01766","SJAG_03914","SJAG_02592","SJAG_04789","SJAG_00043","SJAG_02498","SJAG_02902","SJAG_02472","SJAG_01029","SJAG_02450","SJAG_04067"],"annotation_feature_type":"gene","cv_annotations":{"PSI-MOD":[{"annotations":[81041],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00226"},{"annotations":[80930],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00793"},{"annotations":[81003,80948,81010,80872,81100,80964,81008,81101,81001,80992,80946,81051,80832,80917,80854,80873,81102,80911,80916,80928,80902,81040,80888,80869,81043,81050,81075,80878,80975,80947,81002,80851,80879,80889,80890,81000,80963,81049,80927,81009,81038,80926,80891,80880,80951],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00689"},{"annotations":[80897,81005,80974,80910,81084,81098],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00042"},{"annotations":[80997,80913],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00050"},{"annotations":[81016,81021,80862,81017,81019,80865,81020,81067,81070,80867,80866,81068,81069,80864,80863,81018,81071,80861],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00006"},{"annotations":[81007],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00126"},{"annotations":[81006,81028],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00123"},{"annotations":[81087],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00127"},{"annotations":[80915,80823,80846,80811,80849,80983,80990,81035,81092,81094,80907,80967],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00128"},{"annotations":[80836,119493,119708,80835,119707,119492,119709,119706],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00046"},{"annotations":[80966],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00159"},{"annotations":[119801,119802,119699,119803,119775],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:00696"},{"annotations":[80870,81031,81129,81130],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MOD:01154"}]},"cv_name":"PSI-MOD","definition":"Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue.","definition_xrefs":["PubMed:18688235"],"gene_count":61,"genes_by_uniquename":{"SJAG_00043":null,"SJAG_00096":null,"SJAG_00109":null,"SJAG_00254":null,"SJAG_00288":null,"SJAG_00318":null,"SJAG_00331":null,"SJAG_00432":null,"SJAG_00464":null,"SJAG_00733":null,"SJAG_00784":null,"SJAG_00827":null,"SJAG_00937":null,"SJAG_01029":null,"SJAG_01162":null,"SJAG_01488":null,"SJAG_01587":null,"SJAG_01626":null,"SJAG_01671":null,"SJAG_01766":null,"SJAG_01970":null,"SJAG_02183":null,"SJAG_02205":null,"SJAG_02260":null,"SJAG_02388":null,"SJAG_02435":null,"SJAG_02450":null,"SJAG_02472":null,"SJAG_02489":null,"SJAG_02498":null,"SJAG_02504":null,"SJAG_02522":null,"SJAG_02592":null,"SJAG_02694":null,"SJAG_02763":null,"SJAG_02766":null,"SJAG_02827":null,"SJAG_02902":null,"SJAG_02972":null,"SJAG_02980":null,"SJAG_03009":null,"SJAG_03012":null,"SJAG_03032":null,"SJAG_03290":null,"SJAG_03524":null,"SJAG_03632":null,"SJAG_03641":null,"SJAG_03671":null,"SJAG_03861":null,"SJAG_03914":null,"SJAG_04067":null,"SJAG_04125":null,"SJAG_04149":null,"SJAG_04238":null,"SJAG_04551":null,"SJAG_04553":null,"SJAG_04789":null,"SJAG_04819":null,"SJAG_04953":null,"SJAG_04972":null,"SJAG_05230":null},"genotype_count":0,"is_obsolete":false,"name":"protein modification","references_by_uniquename":{"PMID:26774782":null,"PMID:31150379":null,"PMID:32915139":null,"PMID:33791858":null,"PMID:34198697":null,"PMID:36408920":null},"synonyms":[{"name":"ModRes","type":"exact"}],"termid":"MOD:00000","terms_by_termid":{"GO:0034599":null,"GO:0034605":null,"GO:0036460":null,"GO:0042149":null,"GO:0071475":null,"GO:0120306":null,"GO:1904547":null,"MOD:00006":null,"MOD:00042":null,"MOD:00046":null,"MOD:00050":null,"MOD:00123":null,"MOD:00126":null,"MOD:00127":null,"MOD:00128":null,"MOD:00159":null,"MOD:00226":null,"MOD:00689":null,"MOD:00696":null,"MOD:00793":null,"MOD:01154":null}}


id: GO:2001127
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a methane from a formic acid.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"formate metabolic process","termid":"GO:0015942"},{"relation_name":"is_a","term_name":"methanogenesis","termid":"GO:0015948"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006091"}],"interesting_parent_ids":["GO:0006091","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"methane biosynthetic process from formic acid","termid":"GO:2001127"}


id: PBO:0040565
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"beta-1,4-galactosyltransferase 1","termid":"PBO:0040565"}


id: GO:0097552
data:
  {"annotated_genes":["SJAG_05373"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[79782],"is_not":false,"summary":null,"term":"GO:0097552"}]},"cv_name":"biological_process","definition":"The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences.","definition_xrefs":["GOC:di","PMID:22214610"],"direct_ancestors":[{"relation_name":"is_a","term_name":"recombinational repair","termid":"GO:0000725"},{"relation_name":"is_a","term_name":"mitochondrial double-strand break repair","termid":"GO:0097551"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05373":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006281"},{"rel_name":"is_a","termid":"GO:0006310"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0006310","GO:0006259","GO:0008150","GO:0006281"],"is_obsolete":false,"name":"mitochondrial double-strand break repair via homologous recombination","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"mtDSB repair via homologous recombination","type":"exact"}],"termid":"GO:0097552","terms_by_termid":{"GO:0097552":null}}


id: PBO:0030278
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_vegetative_cell_population_growth_rate","termid":"PBO:0030278"}


id: GO:0005930
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.","definition_xrefs":["GOC:bf","GOC:cilia","ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cytoskeleton","termid":"GO:0005856"},{"relation_name":"part_of","term_name":"ciliary plasm","termid":"GO:0097014"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005575","GO:0005737"],"is_obsolete":false,"name":"axoneme","secondary_identifiers":["GO:0035085","GO:0035086","Wikipedia:Axoneme"],"synonyms":[{"name":"ciliary axoneme","type":"exact"},{"name":"cilium axoneme","type":"exact"},{"name":"flagellar axoneme","type":"exact"},{"name":"flagellum axoneme","type":"exact"}],"termid":"GO:0005930"}


id: MONDO:0007767
data:
  {"annotated_genes":["SJAG_01151"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86035],"is_not":false,"summary":null,"term":"MONDO:0007767"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated hyperparathyroidism","termid":"MONDO:0015027"},{"relation_name":"is_a","term_name":"bone neoplasm","termid":"MONDO:0019060"},{"relation_name":"is_a","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"abnormal mineralization disorder","termid":"MONDO:0800096"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01151":null},"genotype_count":0,"is_obsolete":false,"name":"hyperparathyroidism 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:145000","MEDGEN:333554","UMLS:C1840402","GARD:18253"],"synonyms":[{"name":"HRPT1","type":"related"},{"name":"hyperparathyroidism 1","type":"exact"},{"name":"hyperparathyroidism type 1","type":"exact"},{"name":"hyperparathyroidism, familial isolated primary","type":"related"},{"name":"hyperparathyroidism, familial primary","type":"exact"},{"name":"parathyroid adenoma, familial","type":"related"}],"termid":"MONDO:0007767","terms_by_termid":{"MONDO:0007767":null},"xrefs":{"Monarch":{"xref_id":"0007767"}}}


id: MONDO:0018840
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A congenital disorder usually inherited in an autosomal recessive pattern. It affects the hepatobiliary system and the kidneys. It is characterized by liver fibrosis, portal hypertension, and renal cysts.","definition_xrefs":["NCIT:C97071"],"direct_ancestors":[{"relation_name":"is_a","term_name":"biliary tract disorder","termid":"MONDO:0004868"},{"relation_name":"is_a","term_name":"cirrhosis, familial","termid":"MONDO:0007329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0019303"},{"rel_name":"is_a","termid":"MONDO:0002515"}],"interesting_parent_ids":["MONDO:0019303","MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"isolated congenital hepatic fibrosis","secondary_identifiers":["NANDO:2200936","GARD:21995","NANDO:2100267","NORD:1225","Orphanet:485426","UMLS:C0009714","ICD9:777.8","MEDGEN:40449","MESH:C562378","SCTID:79607001"],"synonyms":[{"name":"Congenital Hepatic Fibrosis","type":"exact"},{"name":"congenital fibrose liver","type":"related"},{"name":"congenital hepatic fibrosis","type":"exact"},{"name":"isolated CHF","type":"broad"},{"name":"nonsyndromic congenital hepatic fibrosis","type":"exact"}],"termid":"MONDO:0018840","xrefs":{"Monarch":{"xref_id":"0018840"}}}


id: PBO:0004666
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sds3-like family protein Dep1","termid":"PBO:0004666"}


id: MONDO:0010668
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Skeletal dysplasia-intellectual disability syndrome combines skeletal anomalies (short stature, ridging of the metopic suture, fusion of cervical vertebrae, thoracic hemivertebrae, scoliosis, sacral hypoplasia and short middle phalanges) and mild intellectual deficit. It has been described in four male cousins in three sibships. Glucose intolerance was present in three cases, and imperforated anus in one case. Carrier females had minor manifestations (fusion of cervical vertebrae and glucose intolerance). Transmission seems to be X-linked.","definition_xrefs":["Orphanet:1436"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"spondylodysplastic dysplasia","termid":"MONDO:0019694"},{"relation_name":"is_a","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"skeletal dysplasia-intellectual disability syndrome","secondary_identifiers":["MEDGEN:326949","MESH:C564101","SCTID:722478008","UMLS:C1839729","GARD:3520","OMIM:309620"],"synonyms":[{"name":"Christian syndrome","type":"exact"},{"name":"MRSD","type":"related"},{"name":"X-linked skeletal dysplasia-intellectual disability syndrome","type":"related"},{"name":"intellectual disability skeletal dysplasia abducens palsy","type":"related"},{"name":"intellectual disability, skeletal dysplasia, and abducens palsy","type":"related"},{"name":"mental retardation skeletal dysplasia abducens palsy","type":"related"},{"name":"mental retardation, skeletal dysplasia, and abducens palsy","type":"related"},{"name":"mental retardation-skeletal dysplasia","type":"exact"}],"termid":"MONDO:0010668","xrefs":{"Monarch":{"xref_id":"0010668"}}}


id: GO:0042838
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.","definition_xrefs":["GOC:mah","ISBN:0198506732","GOC:jsg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate catabolic process","termid":"GO:0016052"},{"relation_name":"is_a","term_name":"glucarate catabolic process","termid":"GO:0019394"},{"relation_name":"is_a","term_name":"D-glucarate metabolic process","termid":"GO:0042836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0005975","GO:0008150"],"is_obsolete":false,"name":"D-glucarate catabolic process","synonyms":[{"name":"D-glucarate breakdown","type":"exact"},{"name":"D-glucarate catabolism","type":"exact"},{"name":"D-glucarate degradation","type":"exact"},{"name":"saccharate catabolic process","type":"exact"},{"name":"saccharate catabolism","type":"exact"}],"termid":"GO:0042838"}


id: FYPO:0007536
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to regions of chromatin containing genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:30282034","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to chromatin during vegetative growth","termid":"FYPO:0001509"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001312","FYPO:0000257","FYPO:0000138"],"is_obsolete":false,"name":"normal protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth","synonyms":[{"name":"normal protein localisation to chromatin at RNA polymerase II-transcribed genes during vegetative growth","type":"exact"},{"name":"normal protein localization to chromatin at RNA polymerase II-regulated genes during vegetative growth","type":"exact"},{"name":"normal protein localization to chromatin at RNA polymerase II-transcribed genes during mitotic cell cycle","type":"related"},{"name":"normal protein localization to chromatin at polymerase II transcribed genes during vegetative growth","type":"exact"}],"termid":"FYPO:0007536"}


id: GO:1990932
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.","definition_xrefs":["PMID:15527424","PMID:11716358"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA binding","termid":"GO:0019843"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005488","GO:0003723","GO:0003674"],"is_obsolete":false,"name":"5.8S rRNA binding","termid":"GO:1990932"}


id: PBO:0063895
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol glycan anchor biosynthesis class S","termid":"PBO:0063895"}


id: PBO:0046961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 83 member A","termid":"PBO:0046961"}


id: PBO:0041670
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcyclin binding protein pseudogene 3","termid":"PBO:0041670"}


id: MONDO:0016439
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Elastoderma is a rare condition that affects the skin. People affected by elastoderma generally have increased laxity of skin covering a specific area of the body. Decreased recoil of the skin has also been reported. Although any part of the body can be affected, the skin of the neck and extremities (arms and legs, especially at the elbows and/or knees) are most commonly involved. The exact underlying cause is currently unknown; however, it generally occurs sporadically in people with no family history of the condition. There is no standard therapy available for elastoderma. Some cases have been treated with surgical excision (removal of affected skin), but hyperlaxity of skin often returns following the surgery.","direct_ancestors":[{"relation_name":"is_a","term_name":"dermis disorder","termid":"MONDO:0021154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"elastoderma","secondary_identifiers":["Orphanet:228240","ICD9:701.8","SCTID:238832003","GARD:12716","icd11.foundation:1880397739","MEDGEN:590504","UMLS:C0406555"],"termid":"MONDO:0016439","xrefs":{"Monarch":{"xref_id":"0016439"}}}


id: PBO:0003971
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab Escort Protein","termid":"PBO:0003971"}


id: MONDO:0014004
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"bilateral striopallidodentate calcinosis","termid":"MONDO:0008947"},{"relation_name":"is_a","term_name":"idiopathic disease","termid":"MONDO:0700007"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0002039"],"is_obsolete":false,"name":"basal ganglia calcification, idiopathic, 4","secondary_identifiers":["MEDGEN:767235","OMIM:615007","UMLS:C3554321","GARD:15893"],"synonyms":[{"name":"IBGC4","type":"related"},{"name":"basal ganglia calcification, idiopathic, 4","type":"exact"},{"name":"basal ganglia calcification, idiopathic, type 4","type":"exact"}],"termid":"MONDO:0014004","xrefs":{"Monarch":{"xref_id":"0014004"}}}


id: PBO:0073052
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small cysteine and glycine repeat containing 10 (gene/pseudogene)","termid":"PBO:0073052"}


id: MONDO:0100322
data:
  {"annotated_genes":["SJAG_00326","SJAG_00702"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86408],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008972"},{"annotations":[86257],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014743"}]},"cv_name":"mondo","definition":"A peroxisome biogenesis disorder which is due to defect in PEX7 or PEX5. This includes rhizomelic chondrodysplasia punctata due to defect in PEX7 or PEX5, and adult Refsum Disease due to defects in PEX7.","direct_ancestors":[{"relation_name":"is_a","term_name":"peroxisome biogenesis disorder","termid":"MONDO:0019234"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00326":null,"SJAG_00702":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0019053"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0019053","MONDO:0005244","MONDO:0005066","MONDO:0005559","MONDO:0006025"],"is_obsolete":false,"name":"non-Zellweger spectrum disorder","references_by_uniquename":{"PB_REF:0000006":null},"synonyms":[{"name":"non-Zellweger spectrum disorder","type":"exact"}],"termid":"MONDO:0100322","terms_by_termid":{"MONDO:0008972":null,"MONDO:0014743":null},"xrefs":{"Monarch":{"xref_id":"0100322"}}}


id: GO:0043632
data:
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id: MONDO:0000609
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  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete sideroblastic anemia with spinocerebellar ataxia (obsolete MONDO:0000609)","termid":"MONDO:0000609","xrefs":{"Monarch":{"xref_id":"0000609"}}}


id: GO:0102835
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  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (obsolete GO:0102835)","termid":"GO:0102835"}


id: PBO:0002349
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pot1 associated protein Poz1","termid":"PBO:0002349"}


id: GO:0009784
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id: PBO:0063246
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id: GO:2000819
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of nucleotide-excision repair.","definition_xrefs":["GOC:jp","PMID:18836076"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of DNA repair","termid":"GO:0006282"},{"relation_name":"regulates","term_name":"nucleotide-excision repair","termid":"GO:0006289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006281"},{"rel_name":"regulates","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0008150","GO:0006281"],"is_obsolete":false,"name":"regulation of nucleotide-excision repair","synonyms":[{"name":"regulation of NER","type":"exact"},{"name":"regulation of interstrand crosslink repair","type":"related"},{"name":"regulation of intrastrand cross-link repair","type":"related"},{"name":"regulation of pyrimidine-dimer repair, DNA damage excision","type":"exact"}],"termid":"GO:2000819"}


id: PBO:0005381
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  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pombe glycoprotease","termid":"PBO:0005381"}


id: PBO:0059726
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO2 pseudogene 34","termid":"PBO:0059726"}


id: GO:0002143
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id: GO:0048142
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id: GO:0018535
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  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor.","definition_xrefs":["EC:1.5.99.4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors","termid":"GO:0016645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"nicotine dehydrogenase activity","secondary_identifiers":["MetaCyc:NICOTINE-DEHYDROGENASE-RXN","UM-BBD_enzymeID:r0979","RHEA:14769","UM-BBD_enzymeID:r0978"],"synonyms":[{"name":"D-nicotine oxidase activity","type":"related"},{"name":"nicotine oxidase activity","type":"related"},{"name":"nicotine:(acceptor) 6-oxidoreductase (hydroxylating)","type":"related"},{"name":"nicotine:acceptor 6-oxidoreductase (hydroxylating)","type":"related"}],"termid":"GO:0018535"}


id: GO:0070465
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id: FYPO:0009035
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of formamide than normal.","definition_xrefs":["PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002682","FYPO:0000139","FYPO:0005447","FYPO:0000003"],"is_obsolete":false,"name":"resistance to formamide","synonyms":[{"name":"resistance to formamide during mitotic cell cycle","type":"related"},{"name":"resistance to formamide during vegetative growth","type":"exact"},{"name":"resistant to formamide","type":"exact"}],"termid":"FYPO:0009035"}


id: MONDO:0011628
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Propionic acidemia (PA) is an organic aciduria caused by the deficient activity of the propionyl Coenzyme A carboxylase and is characterized by life threatening episodes of metabolic decompensation, neurological dysfunction and that may be complicated by cardiomyopathy.","definition_xrefs":["Orphanet:35"],"direct_ancestors":[{"relation_name":"is_a","term_name":"classic organic aciduria","termid":"MONDO:0019215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"propionic acidemia","secondary_identifiers":["SCTID:69080001","MESH:D056693","NANDO:1200792","DOID:14701","NANDO:2200492","ICD10CM:E71.121","NCIT:C85030","NORD:714","GARD:467","MEDGEN:75694","OMIM:606054","UMLS:C0268579"],"synonyms":[{"name":"GLYCINEMIA, ketotic","type":"exact"},{"name":"Glycinemia, ketotic","type":"related"},{"name":"PCC deficiency","type":"related"},{"name":"Propionicacidemia","type":"related"},{"name":"hyperglycinemia with ketoacidosis and leukopenia","type":"related"},{"name":"ketotic II glycinemia","type":"exact"},{"name":"ketotic glycinemia","type":"exact"},{"name":"ketotic hyperglycinemia","type":"exact"},{"name":"prop","type":"related"},{"name":"propionic acidemia","type":"exact"},{"name":"propionic aciduria","type":"exact"},{"name":"propionyl-CoA carboxylase deficiency","type":"exact"},{"name":"propionyl-Coa carboxylase deficiency","type":"related"}],"termid":"MONDO:0011628","xrefs":{"Monarch":{"xref_id":"0011628"}}}


id: GO:0070122
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond).","definition_xrefs":["Wikipedia:Isopeptidase","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete isopeptidase activity (obsolete GO:0070122)","termid":"GO:0070122"}


id: MONDO:0043343
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Interposition of a portion of the colon (e.g., sigmoid colon) between the liver and the diaphragm. It is associated with abdominal pain, vomiting, constipation, anorexia and volvulus. Chilaiditi anomaly refers to asymptomatic interposition.","definition_xrefs":["MESH:D059269"],"direct_ancestors":[{"relation_name":"is_a","term_name":"colonic disorder","termid":"MONDO:0003409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"Chilaiditi syndrome","secondary_identifiers":["MEDGEN:452355","SCTID:14911005","UMLS:C0267494"],"synonyms":[{"name":"Chilaiditi anomaly","type":"related"},{"name":"Chilaiditi's anomaly","type":"related"},{"name":"Chilaiditi's syndrome","type":"related"},{"name":"Chilaiditis anomaly","type":"related"},{"name":"Chilaiditis syndrome","type":"related"},{"name":"anomaly, Chilaiditi","type":"related"},{"name":"anomaly, Chilaiditi's","type":"related"},{"name":"chilaiditi's syndrome","type":"related"},{"name":"hepatodiaphragmatic colonic interposition","type":"related"},{"name":"subphrenic interposition syndrome","type":"exact"},{"name":"syndrome, Chilaiditi","type":"related"},{"name":"syndrome, Chilaiditi's","type":"related"}],"termid":"MONDO:0043343","xrefs":{"Monarch":{"xref_id":"0043343"}}}


id: PBO:0003884
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial carboxylic acid transporter (predicted)","termid":"PBO:0003884"}


id: MOD:00352
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl 5-omega-hydroxyceramide ester.","definition_xrefs":["RESID:AA0347","PubMed:9651377","PubMed:10411887"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-glutamine residue","termid":"MOD:00907"},{"relation_name":"is_a","term_name":"lipoconjugated residue","termid":"MOD:01155"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:01155"}],"interesting_parent_ids":["MOD:01155"],"is_obsolete":false,"name":"L-glutamyl 5-omega-hydroxyceramide ester","synonyms":[{"name":"(S)-2-amino-5-[30-((2S,3R,4E)-1,3-dihydroxyicos-4-en-2-ylamino)-30-oxotriacontan-1-yloxy]-5-oxopentanoic acid","type":"exact"},{"name":"2-[30-(isoglutamyloxy)triacontanoyl]icosasphingosine","type":"exact"},{"name":"L-glutamyl 5-omega-hydroxyceramide ester","type":"exact"},{"name":"LIPID Omega-hydroxyceramide glutamate ester","type":"exact"}],"termid":"MOD:00352"}


id: GO:0048017
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.","definition_xrefs":["PMID:16088939","GOC:ceb","GOC:bf"],"gene_count":0,"genotype_count":0,"name":"obsolete inositol lipid-mediated signaling (obsolete GO:0048017)","synonyms":[{"name":"inositol lipid-mediated signal transduction","type":"exact"},{"name":"inositol lipid-mediated signalling","type":"exact"},{"name":"inositol phospholipid-mediated signaling","type":"narrow"}],"termid":"GO:0048017"}


id: GO:1904106
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained in, a location within a microvillus.","definition_xrefs":["GO_REF:0000087","GOC:kmv","GOC:TermGenie","PMID:25335890"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization","termid":"GO:0008104"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to microvillus","synonyms":[{"name":"protein localisation in microvillus","type":"exact"},{"name":"protein localisation to microvillus","type":"exact"},{"name":"protein localization in microvillus","type":"exact"}],"termid":"GO:1904106"}


id: PBO:0061033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ninein like","termid":"PBO:0061033"}


id: PBO:0039603
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acidic nuclear phosphoprotein 32 family member C","termid":"PBO:0039603"}


id: MONDO:0031013
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autoimmune form of optic neuritis.","definition_xrefs":["MONDO:patterns/autoimmune"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoimmune disorder of central nervous system","termid":"MONDO:0000568"},{"relation_name":"is_a","term_name":"autoimmune disorder of peripheral nervous system","termid":"MONDO:0000590"},{"relation_name":"is_a","term_name":"optic neuritis","termid":"MONDO:0005885"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005328"],"is_obsolete":false,"name":"autoimmune optic neuritis","secondary_identifiers":["DOID:0040089"],"termid":"MONDO:0031013","xrefs":{"Monarch":{"xref_id":"0031013"}}}


id: PBO:0046090
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 4A2 pseudogene 1","termid":"PBO:0046090"}


id: MOD:01459
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an N-terminal residue to an 4x(2)H labeled alpha-dimethylamino N-terminal residue.","definition_xrefs":["Unimod:199#N-term","PubMed:14670044","OMSSA:190"],"direct_ancestors":[{"relation_name":"is_a","term_name":"4x(2)H labeled dimethylated residue","termid":"MOD:00552"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"4x(2)H labeled alpha-dimethylamino N-terminal residue","synonyms":[{"name":"DiMethyl-CHD2","type":"related"},{"name":"Dimethyl:2H(4)","type":"related"},{"name":"mod190","type":"exact"}],"termid":"MOD:01459"}


id: PBO:0068984
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 228, pseudogene","termid":"PBO:0068984"}


id: PR:O74363
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sqs1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74363"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G-patch and R3H domain-containing protein C30B4.02c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC30B4.02c","synonyms":[{"name":"Spom972h-sqs1","type":"exact"}],"termid":"PR:O74363"}


id: PBO:0082339
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent 5'-flap endonuclease and DNA helicase; tracking protein for flap cleavage during Okazaki fragment maturation; involved in DNA repair/processing of meiotic DNA double strand breaks; cell cycle-dependent localization to telomeric chromatin and replicating chromosomes; required for telomerase-dependent telomere synthesis; stability, localization and nuclease activity regulated by sumoylation; forms nuclear foci upon replication stress; human homolog DNA2 complements yeast dna2 mutant","termid":"PBO:0082339"}


id: RO:0002327
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"capable_of","termid":"RO:0002215"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"enables","termid":"RO:0002327"}


id: MONDO:0014759
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive non-syndromic intellectual disability in which the cause of the disease is a mutation in the HNMT gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0006025","MONDO:0005066"],"is_obsolete":false,"name":"intellectual disability, autosomal recessive 51","secondary_identifiers":["DOID:0081214","GARD:22571","MEDGEN:903243","OMIM:616739","UMLS:C4225220"],"synonyms":[{"name":"HNMT autosomal recessive non-syndromic intellectual disability","type":"exact"},{"name":"MRT51","type":"exact"},{"name":"autosomal recessive non-syndromic intellectual disability caused by mutation in HNMT","type":"exact"},{"name":"intellectual developmental disorder, autosomal recessive 51","type":"exact"},{"name":"intellectual disability, autosomal recessive 51","type":"exact"},{"name":"intellectual disability, autosomal recessive type 51","type":"exact"},{"name":"mental retardation, autosomal recessive 51","type":"exact"},{"name":"mental retardation, autosomal recessive type 51","type":"exact"}],"termid":"MONDO:0014759","xrefs":{"Monarch":{"xref_id":"0014759"}}}


id: PBO:0074184
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 38 member 5","termid":"PBO:0074184"}


id: PBO:0043776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"carboxypeptidase A2","termid":"PBO:0043776"}


id: GO:1904250
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the extent of age-related resistance.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:19694953"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of innate immune response","termid":"GO:0045089"},{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of age-related resistance","termid":"GO:1904248"},{"relation_name":"positively_regulates","term_name":"age-related resistance","termid":"GO:0090644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of age-related resistance","synonyms":[{"name":"activation of ARR","type":"narrow"},{"name":"activation of adult seedling resistance","type":"narrow"},{"name":"activation of age-related resistance","type":"narrow"},{"name":"activation of flowering-induced resistance","type":"narrow"},{"name":"activation of mature seedling resistance","type":"narrow"},{"name":"activation of senescence-induced resistance","type":"narrow"},{"name":"positive regulation of ARR","type":"exact"},{"name":"positive regulation of adult seedling resistance","type":"narrow"},{"name":"positive regulation of flowering-induced resistance","type":"narrow"},{"name":"positive regulation of mature seedling resistance","type":"narrow"},{"name":"positive regulation of senescence-induced resistance","type":"narrow"},{"name":"up regulation of ARR","type":"exact"},{"name":"up regulation of adult seedling resistance","type":"narrow"},{"name":"up regulation of age-related resistance","type":"exact"},{"name":"up regulation of flowering-induced resistance","type":"narrow"},{"name":"up regulation of mature seedling resistance","type":"narrow"},{"name":"up regulation of senescence-induced resistance","type":"narrow"},{"name":"up-regulation of ARR","type":"exact"},{"name":"up-regulation of adult seedling resistance","type":"narrow"},{"name":"up-regulation of age-related resistance","type":"exact"},{"name":"up-regulation of flowering-induced resistance","type":"narrow"},{"name":"up-regulation of mature seedling resistance","type":"narrow"},{"name":"up-regulation of senescence-induced resistance","type":"narrow"},{"name":"upregulation of ARR","type":"exact"},{"name":"upregulation of adult seedling resistance","type":"narrow"},{"name":"upregulation of age-related resistance","type":"exact"},{"name":"upregulation of flowering-induced resistance","type":"narrow"},{"name":"upregulation of mature seedling resistance","type":"narrow"},{"name":"upregulation of senescence-induced resistance","type":"narrow"}],"termid":"GO:1904250"}


id: MONDO:1011584
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Paroxysmal nocturnal hemoglobinuria that occurs in Rhesus monkey.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"paroxysmal nocturnal hemoglobinuria, non-human animal","termid":"MONDO:1011413"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"paroxysmal nocturnal hemoglobinuria, Rhesus monkey","secondary_identifiers":["OMIA:002372-9544"],"termid":"MONDO:1011584","xrefs":{"Monarch":{"xref_id":"1011584"}}}


id: GO:0140031
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a protein upon phosphorylation of the target protein.","definition_xrefs":["PMID:26060076"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modification-dependent protein binding","termid":"GO:0140030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005515","GO:0005488"],"is_obsolete":false,"name":"phosphorylation-dependent protein binding","termid":"GO:0140031"}


id: PBO:0075992
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"STEAP family member 1B","termid":"PBO:0075992"}


id: PBO:0052981
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lactamase beta like 1","termid":"PBO:0052981"}


id: PBO:0048749
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycine-N-acyltransferase like 1 pseudogene 2","termid":"PBO:0048749"}


id: MONDO:0001241
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"neutropenia","termid":"MONDO:0001475"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"transient neonatal neutropenia","secondary_identifiers":["UMLS:C0158997","ICD10CM:P61.5","DOID:11245","MEDGEN:510688","SCTID:55444004","ICD9:776.7"],"termid":"MONDO:0001241","xrefs":{"Monarch":{"xref_id":"0001241"}}}


id: PBO:0067354
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 452, pseudogene","termid":"PBO:0067354"}


id: PBO:0030437
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_tRNA-Asp_C38_methylation","termid":"PBO:0030437"}


id: GO:1990767
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle.","definition_xrefs":["PMID:15937517"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor internalization","termid":"GO:0002031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0016192","GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"prostaglandin receptor internalization","termid":"GO:1990767"}


id: PBO:0038651
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acid phosphatase 1","termid":"PBO:0038651"}


id: PBO:0040234
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"activating transcription factor 6","termid":"PBO:0040234"}


id: MONDO:0021525
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign neoplasm that involves the body of uterus.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uterine benign neoplasm","termid":"MONDO:0000632"},{"relation_name":"is_a","term_name":"corpus uteri neoplasm","termid":"MONDO:0021254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign neoplasm of corpus uteri","secondary_identifiers":["NCIT:C3608","SCTID:92021007","MEDGEN:57808","UMLS:C0153998","ICD9:219.1"],"synonyms":[{"name":"benign corpus uteri neoplasm","type":"exact"},{"name":"benign corpus uteri tumor","type":"exact"},{"name":"benign corpus uteri tumour","type":"exact"},{"name":"benign neoplasm of body of uterus","type":"exact"},{"name":"benign neoplasm of the body of uterus","type":"exact"},{"name":"benign neoplasm of the corpus uteri","type":"exact"},{"name":"benign neoplasm of the uterine body","type":"exact"},{"name":"benign neoplasm of the uterine corpus","type":"exact"},{"name":"benign neoplasm of uterine body","type":"exact"},{"name":"benign neoplasm of uterine corpus","type":"exact"},{"name":"benign tumor of body of uterus","type":"exact"},{"name":"benign tumor of corpus uteri","type":"exact"},{"name":"benign tumor of the body of uterus","type":"exact"},{"name":"benign tumor of the corpus uteri","type":"exact"},{"name":"benign tumor of the uterine body","type":"exact"},{"name":"benign tumor of the uterine corpus","type":"exact"},{"name":"benign tumor of uterine body","type":"exact"},{"name":"benign tumor of uterine corpus","type":"exact"},{"name":"benign tumour of body of uterus","type":"exact"},{"name":"benign tumour of corpus uteri","type":"exact"},{"name":"benign tumour of the body of uterus","type":"exact"},{"name":"benign tumour of the corpus uteri","type":"exact"},{"name":"benign tumour of the uterine body","type":"exact"},{"name":"benign tumour of the uterine corpus","type":"exact"},{"name":"benign tumour of uterine body","type":"exact"},{"name":"benign tumour of uterine corpus","type":"exact"},{"name":"benign uterine body neoplasm","type":"exact"},{"name":"benign uterine body tumor","type":"exact"},{"name":"benign uterine body tumour","type":"exact"},{"name":"benign uterine corpus neoplasm","type":"exact"},{"name":"benign uterine corpus tumor","type":"exact"},{"name":"benign uterine corpus tumour","type":"exact"},{"name":"body of uterus benign neoplasm","type":"exact"}],"termid":"MONDO:0021525","xrefs":{"Monarch":{"xref_id":"0021525"}}}


id: GO:0018624
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H+ + NADH + O2 + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+.","definition_xrefs":["RHEA:16737","EC:1.14.12.11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor","termid":"GO:0016708"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"toluene dioxygenase activity","secondary_identifiers":["MetaCyc:TOLUENE-DIOXYGENASE-RXN","KEGG_REACTION:R03559","UM-BBD_enzymeID:r0253"],"synonyms":[{"name":"toluene 1,2-dioxygenase activity","type":"related"},{"name":"toluene 2,3-dioxygenase activity","type":"related"},{"name":"toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)","type":"related"}],"termid":"GO:0018624"}


id: GO:0008414
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the transfer of a CDP-alcohol group from one compound to another.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete CDP-alcohol phosphotransferase activity (obsolete GO:0008414)","termid":"GO:0008414"}


id: MONDO:0003508
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant germ cell tumor arising from the testis. It represents the rarest of the testicular germ cell tumors. Histologically it is characterized by the presence of syncytiotrophoblasts and cytotrophoblasts.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"testicular trophoblastic tumor","termid":"MONDO:0002871"},{"relation_name":"is_a","term_name":"testicular non-seminomatous germ cell cancer","termid":"MONDO:0003403"},{"relation_name":"is_a","term_name":"choriocarcinoma","termid":"MONDO:0005207"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"choriocarcinoma of testis","secondary_identifiers":["ONCOTREE:TCCA","UMLS:C0238449","DOID:5551","EFO:1000564","icd11.foundation:1972827817","MEDGEN:65969","NCIT:C7733"],"synonyms":[{"name":"choriocarcinoma","type":"related"},{"name":"choriocarcinoma of testis","type":"exact"},{"name":"choriocarcinoma of the testis","type":"exact"},{"name":"testicular choriocarcinoma","type":"exact"},{"name":"testis choriocarcinoma (disease)","type":"exact"}],"termid":"MONDO:0003508","xrefs":{"Monarch":{"xref_id":"0003508"}}}


id: FYPO:0005873
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a secondary septum that is thicker than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased septum thickness","termid":"FYPO:0001406"},{"relation_name":"output_of","term_name":"abnormal secondary cell septum biogenesis","termid":"FYPO:0003211"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000032","FYPO:0001985","FYPO:0000631","FYPO:0000002","FYPO:0001320","FYPO:0005447"],"is_obsolete":false,"name":"increased secondary cell septum thickness","synonyms":[{"name":"increased secondary cell septum thickness during mitotic cell cycle","type":"related"},{"name":"increased secondary cell septum thickness during vegetative growth","type":"exact"},{"name":"increased secondary septum thickness","type":"exact"},{"name":"thick secondary septum","type":"exact"}],"termid":"FYPO:0005873"}


id: MONDO:0043099
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"excluded_subClassOf","term_name":"intellectual disability","termid":"MONDO:0001071"},{"relation_name":"is_a","term_name":"pulmonary valve stenosis","termid":"MONDO:0006936"},{"relation_name":"is_a","term_name":"craniosynostosis","termid":"MONDO:0015469"},{"relation_name":"is_a","term_name":"cardiogenetic disease","termid":"MONDO:0100547"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267","MONDO:0005497"],"is_obsolete":false,"name":"Hordnes Engebretsen Knudtson syndrome","secondary_identifiers":["GARD:2736","MEDGEN:419333","MESH:C536067","UMLS:C2931100"],"synonyms":[{"name":"acrobrachycephaly, ventriculomegaly, pulmonary stenosis, ectopic anus and intellectual disability","type":"related"},{"name":"acrobrachycephaly, ventriculomegaly, pulmonary stenosis, ectopic anus and mental retardation","type":"related"}],"termid":"MONDO:0043099","xrefs":{"Monarch":{"xref_id":"0043099"}}}


id: PATO:0001793
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A spatial quality inhering in a bearer by virtue of the bearer's being located on right side of a another entity.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"position","termid":"PATO:0000140"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"right side of","termid":"PATO:0001793"}


id: PBO:0057995
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3919","termid":"PBO:0057995"}


id: PBO:0086148
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for nuclear envelope fusion during karyogamy; pheromone-regulated; peripheral protein of the nuclear membrane; interacts with Kar5p at the spindle pole body","termid":"PBO:0086148"}


id: PBO:0071319
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L27a pseudogene 3","termid":"PBO:0071319"}


id: PBO:0053633
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 680","termid":"PBO:0053633"}


id: FYPO:0008094
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the number of sites at which the protein Rpa2 accumulates is greater than normal during vegetative growth.","definition_xrefs":["PMID:37237082"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular physical quality phenotype","termid":"FYPO:0004638"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased number of Rpa2 foci during vegetative growth","termid":"FYPO:0008094"}


id: PBO:0080560
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WW domain binding protein 11","termid":"PBO:0080560"}


id: PBO:0109635
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PMS2 C-terminal like (pseudogene)","termid":"PBO:0109635"}


id: GO:0032488
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal.","definition_xrefs":["GOC:mah","PMID:18558478"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Rho protein signal transduction","termid":"GO:0007266"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"Cdc42 protein signal transduction","synonyms":[{"name":"Cdc42 signaling","type":"related"},{"name":"Cdc42 signaling pathway","type":"related"},{"name":"cdc42 signalling pathway","type":"related"}],"termid":"GO:0032488"}


id: PATO:0001171
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way.","definition_xrefs":["merriam-webster:merriam-webster"],"direct_ancestors":[{"relation_name":"is_a","term_name":"elasticity","termid":"PATO:0001031"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elastic","termid":"PATO:0001171"}


id: PBO:0034130
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-mutualistically_interacts_with","termid":"PBO:0034130"}


id: PBO:0083418
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the ribosomal gene RPL7B","termid":"PBO:0083418"}


id: PBO:0045550
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dual specificity phosphatase 5","termid":"PBO:0045550"}


id: MOD:01004
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass","definition_xrefs":["DeltaMass:95"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DeltaMass","termid":"MOD:00947"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diaminopropionyl","termid":"MOD:01004"}


id: PBO:0072681
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RUN and FYVE domain containing 2","termid":"PBO:0072681"}


id: PBO:0079824
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unc-51 like kinase 3","termid":"PBO:0079824"}


id: GO:1900008
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.","definition_xrefs":["PMID:15020466","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging (obsolete GO:1900008)","synonyms":[{"name":"down regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing","type":"related"},{"name":"down regulation of extrachromosomal rDNA circle accumulation during replicative cell aging","type":"related"},{"name":"down regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging","type":"related"},{"name":"down regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging","type":"related"},{"name":"negative regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing","type":"related"},{"name":"negative regulation of extrachromosomal rDNA circle accumulation during replicative cell aging","type":"related"},{"name":"negative regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging","type":"related"}],"termid":"GO:1900008"}


id: PBO:0055817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lactoperoxidase","termid":"PBO:0055817"}


id: MOD:01357
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces two hydrogen atoms of an L-lysine residue containing common isotopes with two (13)C,3x(2)H labeled methyl groups to form a 2x(13)C,6x(2)H labeled dimethylated L-lysine.","definition_xrefs":["PubMed:12686488","PubMed:16335955","Unimod:510#K"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"N6,N6-dimethyl-L-lysine","termid":"MOD:00084"},{"relation_name":"is_a","term_name":"modified L-lysine residue","termid":"MOD:00912"},{"relation_name":"is_a","term_name":"2x(13)C,4x(2)H labeled dimethylated residue","termid":"MOD:00927"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2x(13)C,4x(2)H labeled dimethylated L-lysine","synonyms":[{"name":"DiMethyl-C13HD2","type":"related"},{"name":"Dimethyl:2H(4)13C(2)","type":"related"}],"termid":"MOD:01357"}


id: PBO:0082793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the U2 snRNP; required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing; diploid mutants have a specific defect in MATa1 pre-mRNA splicing which leads to haploid gene expression in diploids","termid":"PBO:0082793"}


id: GO:1904109
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of cholesterol import.","definition_xrefs":["PMID:16772292","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cholesterol transport","termid":"GO:0032376"},{"relation_name":"is_a","term_name":"regulation of cholesterol import","termid":"GO:0060620"},{"relation_name":"positively_regulates","term_name":"cholesterol import","termid":"GO:0070508"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"positive regulation of cholesterol import","synonyms":[{"name":"activation of cholesterol import","type":"narrow"},{"name":"activation of cholesterol uptake","type":"narrow"},{"name":"positive regulation of cholesterol uptake","type":"exact"},{"name":"up regulation of cholesterol import","type":"exact"},{"name":"up regulation of cholesterol uptake","type":"exact"},{"name":"up-regulation of cholesterol import","type":"exact"},{"name":"up-regulation of cholesterol uptake","type":"exact"},{"name":"upregulation of cholesterol import","type":"exact"},{"name":"upregulation of cholesterol uptake","type":"exact"}],"termid":"GO:1904109"}


id: GO:0004850
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.","definition_xrefs":["EC:2.4.2.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine-nucleoside phosphorylase activity","termid":"GO:0016154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016757","GO:0003824","GO:0016740"],"is_obsolete":false,"name":"uridine phosphorylase activity","secondary_identifiers":["MetaCyc:URPHOS-RXN","Reactome:R-HSA-74372","RHEA:24388","Reactome:R-HSA-74376"],"synonyms":[{"name":"UPH","type":"related"},{"name":"UPase activity","type":"related"},{"name":"UrdPase activity","type":"related"},{"name":"pyrimidine phosphorylase activity","type":"broad"},{"name":"uridine:phosphate alpha-D-ribosyltransferase activity","type":"related"}],"termid":"GO:0004850"}


id: PBO:0063217
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protocadherin 7","termid":"PBO:0063217"}


id: GO:0002045
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis.","definition_xrefs":["PMID:16391003"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell adhesion","termid":"GO:0030155"},{"relation_name":"part_of","term_name":"intussusceptive angiogenesis","termid":"GO:0002041"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"regulation of cell adhesion involved in intussusceptive angiogenesis","termid":"GO:0002045"}


id: GO:0001896
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.","definition_xrefs":["PMID:26811896","GOC:add","GOC:jh2","GOC:mtg_apoptosis","PMID:19286987","PMID:10974124"],"direct_ancestors":[{"relation_name":"is_a","term_name":"programmed cell death","termid":"GO:0012501"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"autolysis","secondary_identifiers":["Wikipedia:Autolysis"],"termid":"GO:0001896"}


id: PBO:0086784
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole","termid":"PBO:0086784"}


id: PR:Q9USW4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An acetyl-coenzyme A transporter 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02941","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C21B10.09 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC21B10.09","secondary_identifiers":["UniProtKB:Q9USW4"],"synonyms":[{"name":"Spom972h-SLC33A1","type":"exact"}],"termid":"PR:Q9USW4"}


id: GO:0008165
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete pyrethroid resistance (obsolete GO:0008165)","synonyms":[{"name":"pyrethroid resistance","type":"exact"}],"termid":"GO:0008165"}


id: PBO:0074845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 36B","termid":"PBO:0074845"}


id: PBO:0046896
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FAM20B pseudogene 1","termid":"PBO:0046896"}


id: PBO:0054981
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2395","termid":"PBO:0054981"}


id: PBO:0048416
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GATA binding protein 4","termid":"PBO:0048416"}


id: GO:1900445
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of response to biotic stimulus","termid":"GO:0002833"},{"relation_name":"is_a","term_name":"positive regulation of filamentous growth of a population of unicellular organisms","termid":"GO:1900430"},{"relation_name":"is_a","term_name":"regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus","termid":"GO:1900443"},{"relation_name":"positively_regulates","term_name":"filamentous growth of a population of unicellular organisms in response to biotic stimulus","termid":"GO:0036180"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus","synonyms":[{"name":"activation of filamentous growth of a population of unicellular organisms in response to biotic stimulus","type":"narrow"},{"name":"up regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus","type":"exact"},{"name":"up-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus","type":"exact"},{"name":"upregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus","type":"exact"}],"termid":"GO:1900445"}


id: GO:0061468
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.","definition_xrefs":["GOC:dph","PMID:12734396","PMID:22863006"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular membrane-bounded organelle","termid":"GO:0043231"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"karyomere","termid":"GO:0061468"}


id: GO:0001966
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of an animal in response to touch.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavior","termid":"GO:0007610"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"thigmotaxis","synonyms":[{"name":"stereotaxis","type":"exact"},{"name":"taxis in response to mechanical stimulus","type":"broad"},{"name":"taxis in response to touch stimulus","type":"exact"}],"termid":"GO:0001966"}


id: MONDO:0975834
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 128","secondary_identifiers":["OMIM:620983"],"termid":"MONDO:0975834","xrefs":{"Monarch":{"xref_id":"0975834"}}}


id: GO:0006314
data:
  {"annotated_genes":["SJAG_MIT07","SJAG_MIT05","SJAG_MIT06"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[119421,119429,119430],"is_not":false,"summary":null,"term":"GO:0006314"}]},"cv_name":"biological_process","definition":"Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.","definition_xrefs":["PMID:10487208"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA recombination","termid":"GO:0006310"}],"gene_count":3,"genes_by_uniquename":{"SJAG_MIT05":null,"SJAG_MIT06":null,"SJAG_MIT07":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006310"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006259","GO:0006310"],"is_obsolete":false,"name":"intron homing","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0006314","terms_by_termid":{"GO:0006314":null}}


id: PBO:0079703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBOX5 antisense RNA 1","termid":"PBO:0079703"}


id: PBO:0114501
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Master meiotic regulator active only during meiotic events; activates transcription of early meiotic genes through interaction with Ume6p; regulator of meiotic commitment; phosphorylated by Rim11p; degraded by the 26S proteasome following phosphorylation by Ime2p; transcription is negatively regulated in cis by the IRT1 long noncoding antisense RNA","termid":"PBO:0114501"}


id: PBO:0003603
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial translational activator of cytochrome C oxidase I (predicted)","termid":"PBO:0003603"}


id: SO:0000377
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An enterobacterial RNA that binds the CsrA protein. The CsrB RNAs contain a conserved motif CAGGXXG that is found in up to 18 copies and has been suggested to bind CsrA. The Csr regulatory system has a strong negative regulatory effect on glycogen biosynthesis, glyconeogenesis and glycogen catabolism and a positive regulatory effect on glycolysis. In other bacteria such as Erwinia caratovara the RsmA protein has been shown to regulate the production of virulence determinants, such extracellular enzymes. RsmA binds to RsmB regulatory RNA which is also a member of this family.","direct_ancestors":[{"relation_name":"is_a","term_name":"small_regulatory_ncRNA","termid":"SO:0000370"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CsrB_RsmB_RNA","synonyms":[{"name":"CsrB RsmB RNA","type":"exact"},{"name":"CsrB-RsmB RNA","type":"exact"}],"termid":"SO:0000377"}


id: GO:0140421
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement into cell of externally available heme by receptor-mediated endocytosis.","definition_xrefs":["PMID:28193844"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endocytic iron import into cell","termid":"GO:0140298"},{"relation_name":"is_a","term_name":"heme import into cell","termid":"GO:0140420"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098771"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0016192","GO:0008150","GO:0006810","GO:0098771","GO:0051179"],"is_obsolete":false,"name":"endocytic heme import into cell","synonyms":[{"name":"heme assimilation","type":"broad"}],"termid":"GO:0140421"}


id: PBO:0011483
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C1-5,6,7,8-tetrahydrofolate (THF) synthase, trifunctional enzyme","termid":"PBO:0011483"}


id: GO:0003917
data:
  {"annotated_genes":["SJAG_05193","SJAG_04816"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70853,73026],"is_not":false,"summary":null,"term":"GO:0003917"}]},"cv_name":"molecular_function","definition":"Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.","definition_xrefs":["PMID:8811192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA topoisomerase activity","termid":"GO:0003916"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04816":null,"SJAG_05193":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"}],"interesting_parent_ids":["GO:0016853","GO:0003674","GO:0140097","GO:0003824"],"is_obsolete":false,"name":"DNA topoisomerase type I (single strand cut, ATP-independent) activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["MetaCyc:5.99.1.2-RXN","EC:5.6.2.1"],"synonyms":[{"name":"DNA topoisomerase I activity","type":"narrow"},{"name":"deoxyribonucleate topoisomerase","type":"broad"},{"name":"nicking-closing enzyme activity","type":"related"},{"name":"omega-protein activity","type":"related"},{"name":"relaxing enzyme activity","type":"related"},{"name":"swivelase activity","type":"related"},{"name":"topoisomerase","type":"broad"},{"name":"type I DNA topoisomerase activity","type":"exact"},{"name":"type I topoisomerase activity","type":"exact"},{"name":"untwisting enzyme activity","type":"related"}],"termid":"GO:0003917","terms_by_termid":{"GO:0003917":null}}


id: PBO:0005484
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acyl-coA desaturase (predicted)","termid":"PBO:0005484"}


id: PBO:0055985
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat transmembrane neuronal 3","termid":"PBO:0055985"}


id: GO:0090490
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O.","definition_xrefs":["KEGG_REACTION:R09583"],"gene_count":0,"genotype_count":0,"name":"obsolete L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) (obsolete GO:0090490)","termid":"GO:0090490"}


id: PBO:0045254
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"deoxyribonuclease 1","termid":"PBO:0045254"}


id: GO:0032479
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.","definition_xrefs":["GOC:mah","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cytokine production","termid":"GO:0001817"},{"relation_name":"regulates","term_name":"type I interferon production","termid":"GO:0032606"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of type I interferon production","secondary_identifiers":["Reactome:R-HSA-3134975"],"synonyms":[{"name":"regulation of type I IFN production","type":"exact"}],"termid":"GO:0032479"}


id: GO:1902158
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of response to DNA damage checkpoint signaling","termid":"GO:1902154"},{"relation_name":"is_a","term_name":"regulation of response to G2 DNA damage checkpoint signaling","termid":"GO:1902157"},{"relation_name":"positively_regulates","term_name":"response to G2 DNA damage checkpoint signaling","termid":"GO:0072426"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of response to G2 DNA damage checkpoint signaling","synonyms":[{"name":"activation of G2/M transition DNA damage checkpoint effector process","type":"exact"},{"name":"activation of response to G2 DNA damage checkpoint signaling","type":"narrow"},{"name":"activation of response to signal involved in G2/M transition DNA damage checkpoint","type":"exact"},{"name":"positive regulation of G2/M transition DNA damage checkpoint effector process","type":"exact"},{"name":"positive regulation of response to signal involved in G2/M transition DNA damage checkpoint","type":"exact"},{"name":"up regulation of G2/M transition DNA damage checkpoint effector process","type":"exact"},{"name":"up regulation of response to G2 DNA damage checkpoint signaling","type":"exact"},{"name":"up regulation of response to signal involved in G2/M transition DNA damage checkpoint","type":"exact"},{"name":"up-regulation of G2/M transition DNA damage checkpoint effector process","type":"exact"},{"name":"up-regulation of response to G2 DNA damage checkpoint signaling","type":"exact"},{"name":"up-regulation of response to signal involved in G2/M transition DNA damage checkpoint","type":"exact"},{"name":"upregulation of G2/M transition DNA damage checkpoint effector process","type":"exact"},{"name":"upregulation of response to G2 DNA damage checkpoint signaling","type":"exact"},{"name":"upregulation of response to signal involved in G2/M transition DNA damage checkpoint","type":"exact"}],"termid":"GO:1902158"}


id: PATO:0000191
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000191 learning_and memory (obsolete PATO:0000191)","termid":"PATO:0000191"}


id: PBO:0061256
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"notch receptor 1","termid":"PBO:0061256"}


id: GO:0019020
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.","definition_xrefs":["ISBN:0121585336"],"gene_count":0,"genotype_count":0,"name":"obsolete multipartite viral genome (obsolete GO:0019020)","termid":"GO:0019020"}


id: PBO:0088511
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-protein ligase E3, human BRAP ortholog","termid":"PBO:0088511"}


id: PBO:0069643
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 920, pseudogene","termid":"PBO:0069643"}


id: PBO:0039075
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1-acylglycerol-3-phosphate O-acyltransferase 3","termid":"PBO:0039075"}


id: GO:0036500
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity.","definition_xrefs":["GOC:PARL","GOC:bf","PMID:22013210"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ER-nucleus signaling pathway","termid":"GO:0006984"},{"relation_name":"is_a","term_name":"endoplasmic reticulum unfolded protein response","termid":"GO:0030968"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"ATF6-mediated unfolded protein response","secondary_identifiers":["Reactome:R-HSA-381033"],"synonyms":[{"name":"ATF6 branch of UPR","type":"exact"},{"name":"ATF6 signal transduction pathway","type":"broad"},{"name":"ATF6 signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"ATF6-alpha UPR branch","type":"narrow"},{"name":"ATF6-beta UPR branch","type":"narrow"},{"name":"UPR signaling by ATF6 stress sensor","type":"exact"},{"name":"activating transcription factor 6 signaling in unfolded protein response","type":"exact"},{"name":"endoplasmic reticulum unfolded protein response; ATF6 signaling","type":"exact"}],"termid":"GO:0036500"}


id: MONDO:0008811
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"XK aprosencephaly is a very rare syndromic type of cerebral malformation characterized by aprosencephaly (absence of telencephalon and diencephalon), oculo-facial anomalies (i.e. ocular hypotelorism or cyclopia, malformation/absence of nasal structures, cleft lip), preaxial limb defects (i.e. hypoplastic hands, absent halluces) and various other anomalies including ambiguous genitalia, imperforate anus, and vertebral anomalies. The syndrome is thought to have an autosomal recessive mode of inheritance.","definition_xrefs":["Orphanet:3469"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brain disorder","termid":"MONDO:0005560"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"XK aprosencephaly","secondary_identifiers":["SCTID:277921008","UMLS:C0795952","GARD:424","MESH:C536767","icd11.foundation:1805259428","OMIM:207770","MEDGEN:167087"],"synonyms":[{"name":"Garcia-Lurie syndrome","type":"exact"},{"name":"XK aprosencephaly syndrome","type":"related"},{"name":"XK-aprosencephaly","type":"exact"},{"name":"XK-aprosencephaly syndrome","type":"related"},{"name":"Xk syndrome","type":"related"},{"name":"aprosencephaly syndrome","type":"related"},{"name":"aprosencephaly-atelencephaly syndrome","type":"related"},{"name":"atelencephaly","type":"related"}],"termid":"MONDO:0008811","xrefs":{"Monarch":{"xref_id":"0008811"}}}


id: MONDO:0017613
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intellectual disability-hypotonia-skin hyperpigmentation syndrome","secondary_identifiers":["Orphanet:3050"],"synonyms":[{"name":"Medrano Roldan syndrome","type":"related"},{"name":"Medrano-Roldan syndrome","type":"exact"}],"termid":"MONDO:0017613","xrefs":{"Monarch":{"xref_id":"0017613"}}}


id: MONDO:0018392
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete male infertility with spermatogenesis disorder due to single gene mutation (obsolete MONDO:0018392)","secondary_identifiers":["Orphanet:399786"],"termid":"MONDO:0018392","xrefs":{"Monarch":{"xref_id":"0018392"}}}


id: PBO:0038735
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin like 7B","termid":"PBO:0038735"}


id: GO:1904809
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of dense core granule transport.","definition_xrefs":["GO_REF:0000058","PMID:22699897","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of intracellular transport","termid":"GO:0032386"},{"relation_name":"regulates","term_name":"dense core granule transport","termid":"GO:1901950"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of dense core granule transport","synonyms":[{"name":"regulation of dense core vesicle transport","type":"exact"}],"termid":"GO:1904809"}


id: MONDO:0014377
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the HCN1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"undetermined early-onset epileptic encephalopathy","termid":"MONDO:0018614"},{"relation_name":"is_a","term_name":"neonatal-onset developmental and epileptic encephalopathy","termid":"MONDO:0100455"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0004736","MONDO:0005066","MONDO:0005027"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 24","secondary_identifiers":["OMIM:615871","DOID:0080429","MEDGEN:862968","UMLS:C4014531","GARD:16024"],"synonyms":[{"name":"DEE24","type":"exact"},{"name":"EIEE24","type":"exact"},{"name":"HCN1 early infantile epileptic encephalopathy","type":"exact"},{"name":"developmental and epileptic encephalopathy 24","type":"exact"},{"name":"early infantile epileptic encephalopathy caused by mutation in HCN1","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 24","type":"exact"},{"name":"epileptic encephalopathy, early infantile, type 24","type":"exact"}],"termid":"MONDO:0014377","xrefs":{"Monarch":{"xref_id":"0014377"}}}


id: GO:0080026
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.","definition_xrefs":["PMID:18725356"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to auxin","termid":"GO:0009733"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to indolebutyric acid","synonyms":[{"name":"response to IBA stimulus","type":"exact"},{"name":"response to indole-3-butyric acid stimulus","type":"narrow"},{"name":"response to indolebutyric acid stimulus","type":"exact"}],"termid":"GO:0080026"}


id: MONDO:0850287
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An intrinsic asthma that is characertized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs.","definition_xrefs":["DOID:0080822"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intrinsic asthma","termid":"MONDO:0004765"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aspirin-induced respiratory disease","termid":"MONDO:0850287","xrefs":{"Monarch":{"xref_id":"0850287"}}}


id: MOD:01989
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-cysteine residue and an L-tyrosine residue by a thioether bond to form 2-(S-L-cysteinyl)-D-tyrosine.","definition_xrefs":["PubMed:21526839","RESID:AA0626"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stereoisomerized residue","termid":"MOD:00664"},{"relation_name":"is_a","term_name":"alpha-carbon thioether crosslinked residues","termid":"MOD:01992"},{"relation_name":"is_a","term_name":"crosslinked L-tyrosine residue","termid":"MOD:02058"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"2-(L-cystein-S-yl)-D-tyrosine","synonyms":[{"name":"(2R,5S)-2,5-diamino-5-carboxyl-6-(hydroxyphenyl)-4-thiahexanoic acid","type":"exact"},{"name":"(2S)-2-amino-2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-3-(4-hydroxyphenyl)propanoic acid","type":"exact"},{"name":"alpha-(L-cystein-S-yl)-D-tyrosine","type":"exact"}],"termid":"MOD:01989"}


id: PBO:0027209
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_telomeric_heterochromatin_during_horsetail_movement","termid":"PBO:0027209"}


id: PBO:0047420
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box and WD repeat domain containing 10B","termid":"PBO:0047420"}


id: PATO:0000493
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000493 amplitude value (obsolete PATO:0000493)","termid":"PATO:0000493"}


id: MONDO:0003658
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A group of lymphomas displaying molecular, morphologic, immunophenotypic, and clinical overlap between classical Hodgkin lymphoma and diffuse large B-cell lymphoma. This term particularly applies to mediastinal lymphomas with overlapping features of mediastinal (thymic) large B-cell lymphoma and classical Hodgkin lymphoma.","definition_xrefs":["NCIT:C37869"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lymphoma","termid":"MONDO:0005062"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma","secondary_identifiers":["ICDO:9596/3","UMLS:C1333878","GARD:10897","DOID:5822","MEDGEN:234323"],"synonyms":[{"name":"B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and Classic Hodgkin lymphoma","type":"exact"},{"name":"B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma","type":"exact"},{"name":"Gray zone lymphoma","type":"exact"},{"name":"Grey zone lymphoma","type":"exact"},{"name":"Hodgkin-like anaplastic large cell lymphoma","type":"exact"},{"name":"large B-cell lymphoma with Hodgkin features","type":"exact"}],"termid":"MONDO:0003658","xrefs":{"Monarch":{"xref_id":"0003658"}}}


id: GO:1901919
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.","definition_xrefs":["PMID:22570495","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of nuclease activity","termid":"GO:0032075"},{"relation_name":"is_a","term_name":"positive regulation of hydrolase activity","termid":"GO:0051345"},{"relation_name":"is_a","term_name":"regulation of ribonuclease activity","termid":"GO:0060700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of exoribonuclease activity","synonyms":[{"name":"activation of exoribonuclease activity","type":"narrow"},{"name":"up regulation of exoribonuclease activity","type":"exact"},{"name":"up-regulation of exoribonuclease activity","type":"exact"},{"name":"upregulation of exoribonuclease activity","type":"exact"}],"termid":"GO:1901919"}


id: PBO:0002703
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eIF2 alpha kinase Hri1","termid":"PBO:0002703"}


id: PR:O59760
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC1020.07 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O59760"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized hydrolase C1020.07 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1020.07","synonyms":[{"name":"Spom972h-SPCC1020.07","type":"exact"}],"termid":"PR:O59760"}


id: PBO:0033779
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_attachment_of_mitotic_spindle_microtubules_to_kinetochore","termid":"PBO:0033779"}


id: PBO:0088801
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab GAP","termid":"PBO:0088801"}


id: GO:0051434
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a BH3 protein domain, present in Bcl-2 family members. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.","definition_xrefs":["PMID:11048732","PMID:9020082","Prosite:PS01259","PMID:12133724","PMID:9704409"],"direct_ancestors":[{"relation_name":"is_a","term_name":"BH domain binding","termid":"GO:0051400"},{"relation_name":"is_a","term_name":"death domain binding","termid":"GO:0070513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"BH3 domain binding","termid":"GO:0051434"}


id: GO:0016324
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The region of the plasma membrane located at the apical end of the cell.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane region","termid":"GO:0098590"},{"relation_name":"part_of","term_name":"apical part of cell","termid":"GO:0045177"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005886","GO:0005575"],"is_obsolete":false,"name":"apical plasma membrane","termid":"GO:0016324"}


id: SO:0000568
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A promoter that can allow for transcription in both directions.","definition_xrefs":["SO:ke","PMID:21601935"],"direct_ancestors":[{"relation_name":"is_a","term_name":"promoter","termid":"SO:0000167"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bidirectional_promoter","synonyms":[{"name":"bidirectional promoter","type":"exact"}],"termid":"SO:0000568"}


id: PBO:0082165
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Adenylosuccinate synthase; catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence","termid":"PBO:0082165"}


id: PBO:0056966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 23c","termid":"PBO:0056966"}


id: PATO:0001442
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in a bearer by virtue of whether the bearer includes all its components.","definition_xrefs":["thefreedictionary.com:thefreedictionary.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"structure","termid":"PATO:0000141"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wholeness","termid":"PATO:0001442"}


id: FYPO:0004417
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to phosphate starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA level during vegetative growth","termid":"FYPO:0001317"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001312","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"normal RNA level during cellular response to phosphate starvation","synonyms":[{"name":"normal RNA accumulation during cellular response to phosphate starvation","type":"related"},{"name":"normal RNA level during cellular response to phosphate starvation during mitotic cell cycle","type":"related"},{"name":"normal RNA level during cellular response to phosphate starvation during vegetative growth","type":"exact"},{"name":"normal RNA level during phosphate starvation","type":"exact"},{"name":"normal mRNA level during cellular response to phosphate starvation","type":"narrow"},{"name":"normal transcript level during cellular response to phosphate starvation","type":"exact"}],"termid":"FYPO:0004417"}


id: GO:0002824
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.","definition_xrefs":["GOC:add","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of adaptive immune response","termid":"GO:0002821"},{"relation_name":"is_a","term_name":"regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","termid":"GO:0002822"},{"relation_name":"positively_regulates","term_name":"adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","termid":"GO:0002460"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","termid":"GO:0002824"}


id: PR:O14028
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC29B12.05c gene.","definition_xrefs":["PRO:DNx","UniProtKB:O14028"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial N(5)-glutamine methyltransferase mtq1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC29B12.05c","synonyms":[{"name":"Spom972h-SPAC29B12.05c","type":"exact"}],"termid":"PR:O14028"}


id: PBO:0061884
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"OPA1 antisense RNA 1","termid":"PBO:0061884"}


id: PBO:0086931
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane; exocyst association is negatively regulated via phosphorylation by Cdc5p during cytokinesis","termid":"PBO:0086931"}


id: PBO:0058037
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4258","termid":"PBO:0058037"}


id: MONDO:0015647
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Thinking seizures is a rare neurologic disease characterized by seizures induced by specific cognitive tasks, such as calculation or solving arithmetic problems (e.g Sudoku puzzle), playing thinking games (e.g. Rubik's cube, chess, cards), thinking, making decisions and abstract reasoning. Idiopathic generalized seizures are mainly involved, but partial epilepsies may, in rare cases, be observed.","definition_xrefs":["Orphanet:166424"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reflex epilepsy","termid":"MONDO:0017768"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"thinking seizures","secondary_identifiers":["MEDGEN:1647683","SCTID:763622006","GARD:20080","UMLS:C4706523"],"termid":"MONDO:0015647","xrefs":{"Monarch":{"xref_id":"0015647"}}}


id: PBO:0029288
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_Mei2_nuclear_dot","termid":"PBO:0029288"}


id: PBO:0047708
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"formin like 2","termid":"PBO:0047708"}


id: PBO:0083867
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box protein and component of SCF ubiquitin ligase complexes; involved in ubiquitin-dependent protein catabolism; readily monoubiquitinated in vitro by SCF-Ubc4 complexes; SCF-Ucc1 regulates level of Cit2 citrate synthase protein to maintain citrate homeostasis, acts as metabolic switch for glyoxylate cycle; UCC1 transcription is downregulated in cells grown on C2-compounds","termid":"PBO:0083867"}


id: PBO:0076033
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"STK32A antisense RNA 1","termid":"PBO:0076033"}


id: PBO:0028347
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_CENP-A_containing_chromatin","termid":"PBO:0028347"}


id: PBO:0087639
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to sites of exocytosis prior to SNARE-mediated fusion; PtdIns[4,5]P2-binding protein that localizes to exocytic sites in a Rho1p-dependent, actin-independent manner, targeting and anchoring the exocyst to the plasma membrane with Exo70p; direct GTP Rho1p effector; required for ER inheritance; relocalizes away from bud neck upon DNA replication stress","termid":"PBO:0087639"}


id: GO:0071514
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The establishment of epigenetic modifications (imprints) during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation.","definition_xrefs":["PMID:31965998","PMID:31896690","PMID:24492710"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epigenetic programming of gene expression","termid":"GO:0043045"},{"relation_name":"part_of","term_name":"germ cell development","termid":"GO:0007281"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006325"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0006325","GO:0008150"],"is_obsolete":false,"name":"genomic imprinting","synonyms":[{"name":"DNA imprinting","type":"exact"},{"name":"establishment of genomic imprinting","type":"exact"},{"name":"genetic imprinting","type":"exact"}],"termid":"GO:0071514"}


id: PBO:0038952
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADIPOQ antisense RNA 1","termid":"PBO:0038952"}


id: GO:0072513
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).","definition_xrefs":["GOC:BHF","GOC:mah","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of secondary heart field cardioblast proliferation","termid":"GO:0003266"},{"relation_name":"is_a","term_name":"positive regulation of cell population proliferation","termid":"GO:0008284"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of secondary heart field cardioblast proliferation","synonyms":[{"name":"negative regulation of second heart field cardioblast proliferation","type":"exact"}],"termid":"GO:0072513"}


id: GO:1903019
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.","definition_xrefs":["GO_REF:0000058","GOC:rl","GOC:BHF","PMID:23544079","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein metabolic process","termid":"GO:0051248"},{"relation_name":"is_a","term_name":"regulation of glycoprotein metabolic process","termid":"GO:1903018"},{"relation_name":"negatively_regulates","term_name":"glycoprotein metabolic process","termid":"GO:0009100"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of glycoprotein metabolic process","synonyms":[{"name":"down regulation of glycoprotein metabolic process","type":"exact"},{"name":"down regulation of glycoprotein metabolism","type":"exact"},{"name":"down-regulation of glycoprotein metabolic process","type":"exact"},{"name":"down-regulation of glycoprotein metabolism","type":"exact"},{"name":"downregulation of glycoprotein metabolic process","type":"exact"},{"name":"downregulation of glycoprotein metabolism","type":"exact"},{"name":"inhibition of glycoprotein metabolic process","type":"narrow"},{"name":"inhibition of glycoprotein metabolism","type":"narrow"},{"name":"negative regulation of glycoprotein metabolism","type":"exact"}],"termid":"GO:1903019"}


id: GO:0045862
data:
  {"annotated_genes":["SJAG_03048","SJAG_00071","SJAG_01131","SJAG_01544","SJAG_00712","SJAG_01489","SJAG_00766","SJAG_04477","SJAG_03699","SJAG_00642","SJAG_01210","SJAG_02723"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[89307],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905786"},{"annotations":[67707,69128,65920,61599,67315,68592],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901800"},{"annotations":[102743,107030,117456,112096,109273],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032436"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of proteolysis","termid":"GO:0030162"},{"relation_name":"is_a","term_name":"positive regulation of protein metabolic process","termid":"GO:0051247"},{"relation_name":"positively_regulates","term_name":"proteolysis","termid":"GO:0006508"}],"gene_count":12,"genes_by_uniquename":{"SJAG_00071":null,"SJAG_00642":null,"SJAG_00712":null,"SJAG_00766":null,"SJAG_01131":null,"SJAG_01210":null,"SJAG_01489":null,"SJAG_01544":null,"SJAG_02723":null,"SJAG_03048":null,"SJAG_03699":null,"SJAG_04477":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of proteolysis","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000108":null},"synonyms":[{"name":"activation of proteolysis","type":"narrow"},{"name":"positive regulation of peptidolysis","type":"exact"},{"name":"stimulation of proteolysis","type":"narrow"},{"name":"up regulation of proteolysis","type":"exact"},{"name":"up-regulation of proteolysis","type":"exact"},{"name":"upregulation of proteolysis","type":"exact"}],"termid":"GO:0045862","terms_by_termid":{"GO:0032436":null,"GO:1901800":null,"GO:1905786":null}}


id: PBO:0056426
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule affinity regulating kinase 1","termid":"PBO:0056426"}


id: MONDO:0017582
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare adenocarcinoma with poor prognosis, arising from the adenohypophysial cells of the anterior lobe of the pituitary gland or pre-existing adenomas. The majority are hormonally functioning neoplasms, usually producing prolactin or ACTH. The diagnosis is based on the presence of metastases. Syndromes associated with pituitary gland carcinomas include hyperprolactinemia, Cushing disease, and acromegaly.","definition_xrefs":["NCIT:C4536"],"direct_ancestors":[{"relation_name":"is_a","term_name":"head and neck carcinoma","termid":"MONDO:0002038"},{"relation_name":"is_a","term_name":"pituitary cancer","termid":"MONDO:0002109"},{"relation_name":"is_a","term_name":"bone carcinoma","termid":"MONDO:0002415"},{"relation_name":"is_a","term_name":"adenocarcinoma","termid":"MONDO:0004970"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"pituitary adenocarcinoma","secondary_identifiers":["SCTID:254955001","DOID:4916","UMLS:C0346300","HP:0011763","MEDGEN:91096","ICDO:8272/3","GARD:9371","ONCOTREE:PTCA","Orphanet:300385"],"synonyms":[{"name":"PTCA","type":"related"},{"name":"cancer of pituitary","type":"broad"},{"name":"cancer of pituitary gland","type":"broad"},{"name":"cancer of the pituitary","type":"broad"},{"name":"cancer of the pituitary gland","type":"broad"},{"name":"carcinoma of pituitary","type":"exact"},{"name":"carcinoma of pituitary gland","type":"exact"},{"name":"carcinoma of the pituitary","type":"exact"},{"name":"carcinoma of the pituitary gland","type":"exact"},{"name":"pituitary adenocarcinoma (disease)","type":"exact"},{"name":"pituitary carcinoma","type":"exact"},{"name":"pituitary gland adenocarcinoma","type":"exact"},{"name":"pituitary gland cancer","type":"broad"},{"name":"pituitary gland carcinoma","type":"exact"}],"termid":"MONDO:0017582","xrefs":{"Monarch":{"xref_id":"0017582"}}}


id: GO:0002118
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.","definition_xrefs":["GOC:hjd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"behavior","termid":"GO:0007610"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"aggressive behavior","secondary_identifiers":["Wikipedia:Aggression"],"synonyms":[{"name":"aggression","type":"exact"}],"termid":"GO:0002118"}


id: GO:0032131
data:
  {"annotated_genes":["SJAG_01971","SJAG_04778"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[101939],"is_not":false,"summary":null,"term":"GO:0032131"},{"annotations":[88535],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0032132"}]},"cv_name":"molecular_function","definition":"Binding to an alkylated residue in DNA.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"damaged DNA binding","termid":"GO:0003684"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01971":null,"SJAG_04778":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003677"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003677","GO:0003674"],"is_obsolete":false,"name":"alkylated DNA binding","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0032131","terms_by_termid":{"GO:0032131":null,"GO:0032132":null}}


id: PBO:0085782
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of the MutS family; forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans","termid":"PBO:0085782"}


id: GO:0120166
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium.","definition_xrefs":["PMID:20739093","PMID:6235212","PMID:125266","PMID:25311923","PMID:4410944","PMID:6235211","DOI:10.1007/978-3-642-00286-1_2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reproductive fruiting body development","termid":"GO:0030582"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protoperithecium formation","termid":"GO:0120166"}


id: GO:0102348
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: behenoyl-CoA + NADP = trans-2-docosenoyl-CoA + NADPH + H+.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete trans-docosan-2-enoyl-CoA reductase activity (obsolete GO:0102348)","termid":"GO:0102348"}


id: GO:0140739
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a NLRP6 inflammasome complex.","definition_xrefs":["PMID:30674671","PMID:34678144"],"direct_ancestors":[{"relation_name":"is_a","term_name":"canonical inflammasome complex assembly","termid":"GO:0140632"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0023052","GO:0065003","GO:0044085","GO:0008150"],"is_obsolete":false,"name":"NLRP6 inflammasome complex assembly","termid":"GO:0140739"}


id: MONDO:0020538
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Malignant dysgerminomatous germ cell tumor of ovary is the most common form of malignant germ cell tumor of ovary, arising from germ cells in the ovary, usually presenting during adolescence with pelvic mass, fever, vaginal bleeding, and acute abdomen and is characterized by bilaterality (around 10% of cases), association with dysgenetic gonads (5 to 10% of cases), elevated serum lactate dehydrogenase (LDH) and human chorionic gonadotrophin (hCG) (in the presence of syncitiotrophoblasts). Malignant dysgerminomatous germ cell tumor of ovary responds well to chemotherapy, potentially sparing patients from infertility and early mortality.","definition_xrefs":["Orphanet:99912"],"direct_ancestors":[{"relation_name":"is_a","term_name":"malignant germ cell tumor of ovary","termid":"MONDO:0018171"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"malignant dysgerminomatous germ cell tumor of ovary","secondary_identifiers":["GARD:19705"],"synonyms":[{"name":"dysgerminomatous germ cell cancer of ovary","type":"exact"},{"name":"dysgerminomatous germ cell cancer of the ovary","type":"exact"},{"name":"malignant dysgerminomatous germ cell tumor of the ovary","type":"related"},{"name":"malignant dysgerminomatous germ cell tumour of the ovary","type":"related"},{"name":"malignant ovarian dysgerminoma","type":"exact"}],"termid":"MONDO:0020538","xrefs":{"Monarch":{"xref_id":"0020538"}}}


id: GO:0031999
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of fatty acid beta-oxidation","termid":"GO:0031998"},{"relation_name":"is_a","term_name":"negative regulation of fatty acid oxidation","termid":"GO:0046322"},{"relation_name":"is_a","term_name":"negative regulation of lipid catabolic process","termid":"GO:0050995"},{"relation_name":"negatively_regulates","term_name":"fatty acid beta-oxidation","termid":"GO:0006635"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"negatively_regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"negative regulation of fatty acid beta-oxidation","synonyms":[{"name":"down regulation of fatty acid beta-oxidation","type":"exact"},{"name":"down-regulation of fatty acid beta-oxidation","type":"exact"},{"name":"downregulation of fatty acid beta-oxidation","type":"exact"},{"name":"inhibition of fatty acid beta-oxidation","type":"narrow"}],"termid":"GO:0031999"}


id: FYPO:0002466
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A mixed population phenotype in which all cells in a population are inviable, and the population includes a mixture of ungerminated spores, germinated spores and cells with abnormal morphology (i.e. size, shape, or structure). The cells with normal morphology arise from division of some of the germinated spores, and may form a microcolony of up to 64 cells.","definition_xrefs":["PomBase:mah","PomBase:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete inviable mixed population including spores, germinated spores and cells with abnormal morphology (obsolete FYPO:0002466)","termid":"FYPO:0002466"}


id: PBO:0076502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taste 2 receptor member 2, pseudogene","termid":"PBO:0076502"}


id: GO:0018289
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The incorporation of molybdenum into a metallo-sulfur cluster.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metal incorporation into metallo-sulfur cluster","termid":"GO:0018282"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"molybdenum incorporation into metallo-sulfur cluster","synonyms":[{"name":"molybdenum incorporation into metallo-sulphur cluster","type":"exact"}],"termid":"GO:0018289"}


id: GO:0140007
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2.","definition_xrefs":["PMID:28199306"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"KICSTOR complex","termid":"GO:0140007"}


id: PBO:0088927
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MEMO1 family, human MEMO1 ortholog, ancient conserved protein, in some organisms this domain is present with ammecr1 which interacts with mediator complex and is implicated in transcription, implicated in signalling and localization to the plasma membrane","termid":"PBO:0088927"}


id: MONDO:0011385
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any disease of a degenerative nature that affects the intervertebral disk.","definition_xrefs":["NCIT:C26983"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete bone deterioration disease (obsolete MONDO:0000834)","termid":"MONDO:0000834"},{"relation_name":"is_a","term_name":"vertebral column disorder","termid":"MONDO:0000812"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"intervertebral disk degenerative disorder","secondary_identifiers":["DOID:90","MEDGEN:102357","EFO:0004994","ICD9:722.6","UMLS:C0158266","MESH:D055959","OMIM:603932","SCTID:77547008"],"synonyms":[{"name":"IDD","type":"exact"},{"name":"cervical disc degenerative disease","type":"narrow"},{"name":"cervical disk degenerative disease","type":"narrow"},{"name":"degenerative disc disease","type":"exact"},{"name":"degenerative disk disease","type":"exact"},{"name":"degenerative disorder of intervertebral disc","type":"exact"},{"name":"degenerative disorder of intervertebral disk","type":"exact"},{"name":"intervertebral Disc Degeneration","type":"exact"},{"name":"intervertebral Disc degenerative disease","type":"exact"},{"name":"intervertebral Disc degenerative disorder","type":"exact"},{"name":"intervertebral disc degeneration","type":"exact"},{"name":"intervertebral disc disease","type":"exact"},{"name":"intervertebral disk degeneration","type":"exact"},{"name":"intervertebral disk degenerative disorder","type":"exact"},{"name":"intervertebral disk disease","type":"exact"},{"name":"lumbar disc degeneration","type":"narrow"},{"name":"lumbar disk degeneration","type":"narrow"},{"name":"vertebral Disc degenerative disease","type":"exact"},{"name":"vertebral Disc degenerative disorder","type":"exact"},{"name":"vertebral disc disease","type":"exact"},{"name":"vertebral disk disease","type":"exact"}],"termid":"MONDO:0011385","xrefs":{"Monarch":{"xref_id":"0011385"}}}


id: MONDO:1012368
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"linear IgA disease, non-human animal","termid":"MONDO:1011749"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"linear IgA disease, dog","secondary_identifiers":["OMIA:001330-9615"],"termid":"MONDO:1012368","xrefs":{"Monarch":{"xref_id":"1012368"}}}


id: PBO:0059673
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 39","termid":"PBO:0059673"}


id: MONDO:0010196
data:
  {"annotated_genes":["SJAG_03898"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87208],"is_not":false,"summary":null,"term":"MONDO:0010196"}]},"cv_name":"mondo","definition":"A rare inherited syndrome characterized by premature aging with onset in the third decade of life and with cardinal clinical features including bilateral cataracts, short stature, graying and thinning of scalp hair, characteristic skin disorders and premature onset of additional age-related disorders.","definition_xrefs":["Orphanet:902"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"excluded_subClassOf","term_name":"hereditary poikiloderma","termid":"MONDO:0016382"},{"relation_name":"excluded_subClassOf","term_name":"premature aging syndrome","termid":"MONDO:0019303"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"autosomal recessive disease","termid":"MONDO:0006025"},{"relation_name":"is_a","term_name":"progeroid syndrome","termid":"MONDO:0015333"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03898":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019303"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019303"],"is_obsolete":false,"name":"Werner syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1864550134","MEDGEN:12147","MESH:D014898","NANDO:1200676","DOID:5688","GARD:7885","MedDRA:10049429","ICD9:259.8","NCIT:C3447","OMIM:277700","SCTID:51626007","UMLS:C0043119","NANDO:2200831"],"synonyms":[{"name":"WRN","type":"related"},{"name":"WS","type":"exact"},{"name":"Werner syndrome","type":"exact"},{"name":"Werner's syndrome","type":"exact"},{"name":"adult premature ageing syndrome","type":"exact"},{"name":"adult premature aging syndrome","type":"exact"},{"name":"adult progeria","type":"exact"}],"termid":"MONDO:0010196","terms_by_termid":{"MONDO:0010196":null},"xrefs":{"Monarch":{"xref_id":"0010196"}}}


id: PBO:0066238
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding motif protein 45","termid":"PBO:0066238"}


id: GO:0002223
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals initiated by the binding of C-type lectin to its receptor on the surface of a target cell, and resulting in cellular activation.","definition_xrefs":["ISBN:0781735149","GO_REF:0000022","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"innate immune response activating cell surface receptor signaling pathway","termid":"GO:0002220"},{"relation_name":"is_a","term_name":"cellular response to lectin","termid":"GO:1990858"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"stimulatory C-type lectin receptor signaling pathway","secondary_identifiers":["Reactome:R-HSA-5621481"],"synonyms":[{"name":"stimulatory C-type lectin receptor signalling pathway","type":"exact"},{"name":"stimulatory Ly49 family receptor signaling pathway","type":"narrow"}],"termid":"GO:0002223"}


id: GO:0009678
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate.","definition_xrefs":["Wikipedia:Proton-pumping_pyrophosphatase","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proton transmembrane transporter activity","termid":"GO:0015078"},{"relation_name":"is_a","term_name":"active monoatomic ion transmembrane transporter activity","termid":"GO:0022853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"diphosphate hydrolysis-driven proton transmembrane transporter activity","secondary_identifiers":["RHEA:13973","EC:7.1.3.1","MetaCyc:TRANS-RXN-370","TC:3.A.10"],"synonyms":[{"name":"H+-exporting diphosphatase","type":"related"},{"name":"PP(i) hydrolysis-driven proton transmembrane transporter activity","type":"exact"},{"name":"hydrogen-translocating pyrophosphatase activity","type":"related"},{"name":"proton-pumping diphosphatase","type":"related"},{"name":"proton-pumping pyrophosphatase","type":"related"},{"name":"proton-translocating pyrophosphatase activity","type":"exact"},{"name":"pyrophosphate hydrolysis-driven proton transmembrane transporter activity","type":"related"}],"termid":"GO:0009678"}


id: PR:Q10218
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppc89 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q10218"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spindle pole body protein ppc89 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4H3.11c","synonyms":[{"name":"Spom972h-ppc89","type":"exact"},{"name":"meiotically up-regulated gene 127 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q10218"}


id: PATO:0005024
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An orientation quality inhering in a bearer by virtue of the bearer having a position that is directed along the longitudinal or anterior-posterior axis.","definition_xrefs":["PATOC:WD"],"direct_ancestors":[{"relation_name":"is_a","term_name":"orientation","termid":"PATO:0000133"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"longitudinal orientation","termid":"PATO:0005024"}


id: GO:0008701
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.","definition_xrefs":["EC:4.1.3.39","RHEA:22624"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxo-acid-lyase activity","termid":"GO:0016833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"4-hydroxy-2-oxovalerate aldolase activity","secondary_identifiers":["MetaCyc:MHPELY-RXN","UM-BBD_enzymeID:r0100","KEGG_REACTION:R00750","GO:0018804"],"synonyms":[{"name":"4-hydroxy-2-ketovalerate aldolase activity","type":"related"},{"name":"4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity","type":"related"},{"name":"4-hydroxy-2-oxopentanoate pyruvate-lyase activity","type":"related"},{"name":"4-hydroxy-2-oxovalerate pyruvate-lyase activity","type":"related"},{"name":"DmpG","type":"related"},{"name":"HOA","type":"related"}],"termid":"GO:0008701"}


id: GO:0010739
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.","definition_xrefs":["GOC:tb","GOC:BHF","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein kinase A signaling","termid":"GO:0010738"},{"relation_name":"is_a","term_name":"positive regulation of intracellular signal transduction","termid":"GO:1902533"},{"relation_name":"positively_regulates","term_name":"protein kinase A signaling","termid":"GO:0010737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of protein kinase A signaling","synonyms":[{"name":"positive regulation of PKA signaling cascade","type":"related"},{"name":"positive regulation of protein kinase A signaling cascade","type":"related"},{"name":"positive regulation of protein kinase A signalling cascade","type":"related"}],"termid":"GO:0010739"}


id: PBO:0042660
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CEA cell adhesion molecule 16, tectorial membrane component","termid":"PBO:0042660"}


id: PBO:0083954
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Gamma-tubulin small complex (gamma-TuSC) receptor; recruits the gamma-TuSC complex to the cytoplasmic side of the SPB, connecting nuclear microtubules to the SPB; involved in astral microtubule formation, stabilization, and with Stu2p, anchoring astral MTs at the cytoplasmic face of the SPB, and regulating plus-end MT dynamics; regulated by Cdc5 kinase","termid":"PBO:0083954"}


id: PR:O13686
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A WD repeat-containing protein 59 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02195","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC11E3.05","secondary_identifiers":["UniProtKB:O13686"],"synonyms":[{"name":"Spom972h-WDR59","type":"exact"}],"termid":"PR:O13686"}


id: MONDO:0014771
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Joubert syndrome in which the cause of the disease is a mutation in the KIAA0556 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Joubert syndrome","termid":"MONDO:0018772"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Joubert syndrome 26","secondary_identifiers":["OMIM:616784","UMLS:C4084843","DOID:0110995","MEDGEN:900415","GARD:16160"],"synonyms":[{"name":"JBTS26","type":"exact"},{"name":"Joubert syndrome 26","type":"exact"},{"name":"Joubert syndrome caused by mutation in KIAA0556","type":"exact"},{"name":"Joubert syndrome type 26","type":"exact"},{"name":"KIAA0556 Joubert syndrome","type":"exact"}],"termid":"MONDO:0014771","xrefs":{"Monarch":{"xref_id":"0014771"}}}


id: MONDO:0013036
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Zechi-Ceide syndrome","secondary_identifiers":["OMIM:612916","MESH:C567865","GARD:10582","UMLS:C2752047","MEDGEN:416693","Orphanet:217017"],"synonyms":[{"name":"Zechi Ceide syndrome","type":"related"},{"name":"Zechi-Ceide syndrome","type":"exact"},{"name":"occipital atretic cephalocele, unusual facies and large feet","type":"related"},{"name":"occipital atretic cephalocele, unusual facies, and large feet","type":"related"},{"name":"occipital atretic cephalocele-unusual facies-large feet syndrome","type":"exact"}],"termid":"MONDO:0013036","xrefs":{"Monarch":{"xref_id":"0013036"}}}


id: GO:0016356
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete organophosphorus susceptibility/resistance (obsolete GO:0016356)","synonyms":[{"name":"organophosphorus susceptibility/resistance","type":"exact"}],"termid":"GO:0016356"}


id: GO:0180002
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.","definition_xrefs":["PMID:28196538"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal tubular secretion","termid":"GO:0097254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"renal zinc excretion","synonyms":[{"name":"renal zinc ion excretion","type":"exact"},{"name":"renal zinc secretion","type":"exact"}],"termid":"GO:0180002"}


id: PATO:0001394
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father.","definition_xrefs":["Wikipedia:http://en.wikipedia.org/wiki/Diploid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"euploid","termid":"PATO:0001393"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diploid","termid":"PATO:0001394"}


id: GO:0044461
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any constituent part of the bacterial-type flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by a transmembrane ion potential, typically a proton or sodium potential.","definition_xrefs":["PMID:25251856","DOI:10.1002/9780470015902.a0000744.pub4","GOC:cilia","GOC:jl","GOC:mtg_sensu","PMID:10572114","PMID:12624192"],"gene_count":0,"genotype_count":0,"name":"obsolete bacterial-type flagellum part (obsolete GO:0044461)","synonyms":[{"name":"flagellin-based flagellum part","type":"exact"}],"termid":"GO:0044461"}


id: GO:0051897
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction","termid":"GO:0051896"},{"relation_name":"is_a","term_name":"positive regulation of intracellular signal transduction","termid":"GO:1902533"},{"relation_name":"positively_regulates","term_name":"phosphatidylinositol 3-kinase/protein kinase B signal transduction","termid":"GO:0043491"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction","secondary_identifiers":["Reactome:R-HSA-1257604","Reactome:R-HSA-165158","Reactome:R-HSA-9603381","Reactome:R-HSA-9028335","Reactome:R-HSA-9027276"],"synonyms":[{"name":"activation of protein kinase B signaling cascade","type":"narrow"},{"name":"positive regulation of AKT signaling cascade","type":"related"},{"name":"positive regulation of AKT signalling cascade","type":"related"},{"name":"positive regulation of PI3K-PKB/Akt pathway","type":"exact"},{"name":"positive regulation of PI3K/Akt signal transduction","type":"exact"},{"name":"positive regulation of PI3K/PKB signal transduction","type":"exact"},{"name":"positive regulation of PKB signaling cascade","type":"related"},{"name":"positive regulation of PKB signalling cascade","type":"related"},{"name":"positive regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction","type":"exact"},{"name":"positive regulation of protein kinase B signaling","type":"related"},{"name":"positive regulation of protein kinase B signaling cascade","type":"related"},{"name":"positive regulation of protein kinase B signalling cascade","type":"related"},{"name":"stimulation of protein kinase B signaling cascade","type":"narrow"},{"name":"up regulation of protein kinase B signaling cascade","type":"related"},{"name":"up-regulation of protein kinase B signaling cascade","type":"related"},{"name":"upregulation of protein kinase B signaling cascade","type":"related"}],"termid":"GO:0051897"}


