# terms

id: GO:0106434
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The reactions involved in isomerization of all trans to all cis retnal.","definition_xrefs":["PMID:21447403"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinal metabolic process","termid":"GO:0042574"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"retinal isomerization","termid":"GO:0106434"}


id: MONDO:0010070
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive brachyolmia","termid":"MONDO:0018662"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497","MONDO:0006025"],"is_obsolete":false,"name":"brachyolmia type 1, Hobaek type","secondary_identifiers":["MEDGEN:338605","MESH:C537099","UMLS:C1849055","OMIM:271530","icd11.foundation:1213374086","GARD:995","Orphanet:93301"],"synonyms":[{"name":"BCYM1A","type":"exact"},{"name":"brachyolmia type 1, Hobaek type","type":"exact"},{"name":"brachyolmia, recessive type of Hobaek","type":"related"},{"name":"spondylodysplasia with Pure brachyolmia","type":"related"}],"termid":"MONDO:0010070","xrefs":{"Monarch":{"xref_id":"0010070"}}}


id: PBO:0027038
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_chromatin_binding_at_centromere_central_core","termid":"PBO:0027038"}


id: PBO:0049947
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypoxia inducible factor 1 subunit alpha","termid":"PBO:0049947"}


id: FYPO:0006425
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) in centromeric regions during the first meiotic nuclear division.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal meiotic sister chromatid cohesion at centromere","termid":"FYPO:0004667"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal meiotic sister chromatid cohesion at centromere during meiosis I","synonyms":[{"name":"normal meiotic sister chromatid cohesion at centromere during first meiotic nuclear division","type":"exact"},{"name":"normal meiotic sister chromatid cohesion, centromeric, during meiosis I","type":"exact"},{"name":"normal sister chromatid cohesion at centromere during meiosis I","type":"exact"}],"termid":"FYPO:0006425"}


id: GO:0019518
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.","definition_xrefs":["GOC:mah","MetaCyc:THREONINE-DEG2-PWY","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycine metabolic process","termid":"GO:0006544"},{"relation_name":"is_a","term_name":"threonine catabolic process","termid":"GO:0006567"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"L-threonine catabolic process to glycine","secondary_identifiers":["Reactome:R-HSA-8849175"],"synonyms":[{"name":"L-threonine breakdown to glycine","type":"exact"},{"name":"L-threonine catabolic process to pyruvate","type":"related"},{"name":"L-threonine catabolism to glycine","type":"exact"},{"name":"L-threonine degradation to glycine","type":"exact"},{"name":"threonine catabolic process to glycine","type":"broad"}],"termid":"GO:0019518"}


id: GO:0000963
data:
  {"annotated_genes":["SJAG_03104","SJAG_02302","SJAG_00255","SJAG_04700","SJAG_00797","SJAG_06586","SJAG_02526","SJAG_00997","SJAG_02288","SJAG_02991","SJAG_01704","SJAG_00865","SJAG_00358","SJAG_04113","SJAG_00077","SJAG_04885","SJAG_04377","SJAG_04367"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[103972],"is_not":false,"summary":null,"term":"GO:0000963"},{"annotations":[96613,90320,104295],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090615"},{"annotations":[110275],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140040"},{"annotations":[71109,114813],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000965"},{"annotations":[79572],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000964"},{"annotations":[88092,80716,70525,118306],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990180"},{"annotations":[78476],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070901"},{"annotations":[75900,119002],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072670"},{"annotations":[117342,94629],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990799"},{"annotations":[93162,76588],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070899"}]},"cv_name":"biological_process","definition":"The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.","definition_xrefs":["GOC:krc","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA processing","termid":"GO:0006396"},{"relation_name":"is_a","term_name":"mitochondrial gene expression","termid":"GO:0140053"}],"gene_count":18,"genes_by_uniquename":{"SJAG_00077":null,"SJAG_00255":null,"SJAG_00358":null,"SJAG_00797":null,"SJAG_00865":null,"SJAG_00997":null,"SJAG_01704":null,"SJAG_02288":null,"SJAG_02302":null,"SJAG_02526":null,"SJAG_02991":null,"SJAG_03104":null,"SJAG_04113":null,"SJAG_04367":null,"SJAG_04377":null,"SJAG_04700":null,"SJAG_04885":null,"SJAG_06586":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140053"},{"rel_name":"is_a","termid":"GO:0010467"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0140053","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"mitochondrial RNA processing","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0000963","terms_by_termid":{"GO:0000963":null,"GO:0000964":null,"GO:0000965":null,"GO:0070899":null,"GO:0070901":null,"GO:0072670":null,"GO:0090615":null,"GO:0140040":null,"GO:1990180":null,"GO:1990799":null}}


id: GO:0070017
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.","definition_xrefs":["PMID:2478219"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005886"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005886"],"is_obsolete":false,"name":"alphav-beta3 integrin-thrombospondin complex","synonyms":[{"name":"ITGAV-ITGB3-THBS1 complex","type":"narrow"}],"termid":"GO:0070017"}


id: GO:0061101
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron differentiation","termid":"GO:0030182"},{"relation_name":"is_a","term_name":"neuroepithelial cell differentiation","termid":"GO:0060563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neuroendocrine cell differentiation","termid":"GO:0061101"}


id: PBO:0088073
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis via its intrinsically disordered regions; stabilizes Rpa190p by deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p, possibly other transporters; localized to the nucleolus; null mutant phenotypes are functionally complemented by human USP36","termid":"PBO:0088073"}


id: GO:0060790
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.","definition_xrefs":["GOC:dph","GOC:tb","GOC:sdb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ectodermal placode formation","termid":"GO:0060788"},{"relation_name":"part_of","term_name":"odontogenesis of dentin-containing tooth","termid":"GO:0042475"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"tooth placode formation","termid":"GO:0060790"}


id: MONDO:0017579
data:
  {"annotated_genes":["SJAG_03145"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86824],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013812"}]},"cv_name":"mondo","definition":"Baraitser-Winter syndrome (BWS) is a malformation syndrome, characterized by facial dysmorphism (hypertelorism with ptosis, broad bulbous nose, ridged metopic suture, arched eyebrows, progressive coarsening of the face), ocular coloboma, pachygyria and/or band heterotopias with antero-posterior gradient, progressive joint stiffening, and intellectual deficit of variable severity, often with severe epilepsy. Pachygyria - epilepsy - intellectual disability - dysmorphism (Fryns-Aftimos syndrome (FA)) corresponds to the appearance of BWS in elderly patients.","definition_xrefs":["Orphanet:2995"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"lissencephaly spectrum disorders","termid":"MONDO:0018838"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03145":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"Baraitser-Winter cerebrofrontofacial syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0060229","GARD:5279","MEDGEN:340016","SCTID:702410002","UMLS:C1853623","OMIMPS:243310","ICD9:759.89"],"synonyms":[{"name":"BRWS","type":"related"},{"name":"Baraitser-Winter syndrome","type":"exact"},{"name":"Fryns-Aftimos syndrome","type":"related"},{"name":"cerebro-frontofacial syndrome, type 3","type":"related"},{"name":"iris coloboma with ptosis hypertelorism and intellectual disability","type":"related"},{"name":"iris coloboma with ptosis hypertelorism and mental retardation","type":"related"},{"name":"trigonocephaly ptosis coloboma","type":"related"},{"name":"trigonocephaly ptosis intellectual disability","type":"related"},{"name":"trigonocephaly ptosis mental retardation","type":"related"}],"termid":"MONDO:0017579","terms_by_termid":{"MONDO:0013812":null},"xrefs":{"Monarch":{"xref_id":"0017579"}}}


id: GO:0120158
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of catabolic process","termid":"GO:0009896"},{"relation_name":"is_a","term_name":"regulation of collagen catabolic process","termid":"GO:0010710"},{"relation_name":"is_a","term_name":"positive regulation of collagen metabolic process","termid":"GO:0010714"},{"relation_name":"positively_regulates","term_name":"collagen catabolic process","termid":"GO:0030574"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of collagen catabolic process","synonyms":[{"name":"activation of collagen catabolic process","type":"narrow"},{"name":"positive regulation of collagen breakdown","type":"exact"},{"name":"positive regulation of collagen catabolism","type":"exact"},{"name":"positive regulation of collagen degradation","type":"exact"},{"name":"up regulation of collagen catabolic process","type":"exact"},{"name":"up-regulation of collagen catabolic process","type":"exact"},{"name":"upregulation of collagen catabolic process","type":"exact"}],"termid":"GO:0120158"}


id: GO:0048162
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.","definition_xrefs":["GOC:mtg_sensu","ISBN:0198542771","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mammalian oogenesis stage","termid":"GO:0022605"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"multi-layer follicle stage","synonyms":[{"name":"mammalian oogenesis stage 5","type":"exact"}],"termid":"GO:0048162"}


id: PBO:0000637
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SWI/SNF complex subunit Snf30","termid":"PBO:0000637"}


id: PBO:0040994
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bolA family member 3","termid":"PBO:0040994"}


id: GO:0044524
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The modification of a protein amino acid by the addition of sulfur.","definition_xrefs":["PMID:19903941","PMID:22169477","GOC:jsg","GOC:jl","PMID:8161529"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification process","termid":"GO:0036211"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein sulfhydration","termid":"GO:0044524"}


id: GO:0035876
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.","definition_xrefs":["PMID:1708436","GOC:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete maintenance of meiotic sister chromatid cohesion, arms (obsolete GO:0035876)","synonyms":[{"name":"maintenance of meiotic sister chromatin cohesion along arms","type":"exact"},{"name":"maintenance of sister chromatin cohesion along arms at meiosis I","type":"exact"}],"termid":"GO:0035876"}


id: SO:0001899
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A repeat region which is part of the regional centromere outer repeat region.","definition_xrefs":["PMID:16407326","SO:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"centromeric_repeat","termid":"SO:0001797"},{"relation_name":"part_of","term_name":"regional_centromere_outer_repeat_region","termid":"SO:0001799"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dh_repeat","synonyms":[{"name":"dh repeat","type":"exact"}],"termid":"SO:0001899"}


id: PBO:0044520
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DAB adaptor protein 1","termid":"PBO:0044520"}


id: PBO:0077500
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 218","termid":"PBO:0077500"}


id: GO:1900318
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amine metabolic process","termid":"GO:0033238"},{"relation_name":"is_a","term_name":"regulation of cellular respiration","termid":"GO:0043457"},{"relation_name":"is_a","term_name":"regulation of alkane biosynthetic process","termid":"GO:1901577"},{"relation_name":"regulates","term_name":"methane biosynthetic process from dimethylamine","termid":"GO:2001129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006091"}],"interesting_parent_ids":["GO:0006091","GO:0008150"],"is_obsolete":false,"name":"regulation of methane biosynthetic process from dimethylamine","termid":"GO:1900318"}


id: GO:0160240
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that promotes premature RNA polymerase II transcription termination of transcripts that are unfavorably configured for transcriptional elongation by releasing RNA polymerase II from bound DNA or promoting RNA polymerase II degradation.","definition_xrefs":["PMID:33385327","PMID:34762484"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear RNA surveillance","termid":"GO:0071027"},{"relation_name":"part_of","term_name":"transcription initiation at RNA polymerase II promoter","termid":"GO:0006367"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0006351"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006351","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"RNA polymerase II transcription initiation surveillance","termid":"GO:0160240"}


id: FYPO:0000123
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are larger than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vacuolar morphology during vegetative growth","termid":"FYPO:0000368"},{"relation_name":"is_a","term_name":"large vacuoles","termid":"FYPO:0007821"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"large vacuoles during vegetative growth","synonyms":[{"name":"enlarged vacuoles during vegetative growth","type":"exact"},{"name":"large vacuoles during mitotic cell cycle","type":"related"},{"name":"vacuole organization defects, large vacuoles","type":"exact"}],"termid":"FYPO:0000123"}


id: MONDO:0006142
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A small cell carcinoma arising from the cervix.","definition_xrefs":["NCIT:C7982"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small cell carcinoma","termid":"MONDO:0000402"},{"relation_name":"is_a","term_name":"cervical carcinoma","termid":"MONDO:0005131"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"cervical small cell carcinoma","secondary_identifiers":["ONCOTREE:SCCE","EFO:1000171","UMLS:C0279674","DOID:6740","MEDGEN:79025"],"synonyms":[{"name":"Cervical small cell cancer","type":"exact"},{"name":"SCCE","type":"related"},{"name":"cervical small cell carcinoma","type":"exact"},{"name":"cervix small cell carcinoma","type":"exact"},{"name":"cervix uteri small cell carcinoma","type":"exact"},{"name":"small cell carcinoma of cervix","type":"exact"},{"name":"small cell carcinoma of cervix uteri","type":"exact"},{"name":"small cell carcinoma of the cervix","type":"exact"},{"name":"small cell carcinoma of the cervix uteri","type":"exact"},{"name":"small cell carcinoma of the uterine cervix","type":"exact"},{"name":"small cell carcinoma of uterine cervix","type":"exact"},{"name":"uterine cervix small cell carcinoma","type":"exact"}],"termid":"MONDO:0006142","xrefs":{"Monarch":{"xref_id":"0006142"}}}


id: GO:0004940
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors.","definition_xrefs":["GOC:mah","IUPHAR_GPCR:1274"],"direct_ancestors":[{"relation_name":"is_a","term_name":"beta-adrenergic receptor activity","termid":"GO:0004939"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"beta1-adrenergic receptor activity","synonyms":[{"name":"beta1 adrenoceptor","type":"exact"}],"termid":"GO:0004940"}


id: PBO:0091557
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"the sequence previously referred to as SPAC27D7.10c was a duplication caused by misassembly of the cosmid","termid":"PBO:0091557"}


id: FYPO:0003680
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing epirubicin.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0002060","FYPO:0000257","FYPO:0002058","FYPO:0000139","FYPO:0002057","FYPO:0000003"],"is_obsolete":false,"name":"normal growth on epirubicin","synonyms":[{"name":"normal cell population growth in presence of epirubicin","type":"exact"},{"name":"normal cell population growth on 4'-epidoxorubicin","type":"exact"},{"name":"normal cell population growth on epirubicin","type":"exact"},{"name":"normal cellular response to epirubicin","type":"related"},{"name":"normal vegetative cell population growth on epirubicin","type":"exact"}],"termid":"FYPO:0003680"}


id: PBO:0053072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipopolysaccharide binding protein","termid":"PBO:0053072"}


id: PBO:0043077
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cholinergic receptor nicotinic alpha 6 subunit","termid":"PBO:0043077"}


id: SO:0000393
data:
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id: GO:0010277
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reactions: chlorophyllide a + 2 H+ + 2 NADPH + 2 O2 = chlorophyllide b + 3 H2O + 2 NADP+.","definition_xrefs":["RHEA:30359"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)","termid":"GO:0016703"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"chlorophyllide a oxygenase activity","secondary_identifiers":["EC:1.14.13.122","GO:0046407"],"synonyms":[{"name":"CAO activity","type":"broad"},{"name":"chlorophyll a oxygenation activity","type":"exact"},{"name":"chlorophyll b synthesis activity","type":"exact"},{"name":"chlorophyll-b synthesis activity","type":"related"},{"name":"chlorophyllide a:oxygen 7-oxidoreduction activity","type":"related"},{"name":"chlorophyllide-a oxygenation activity","type":"related"}],"termid":"GO:0010277"}


id: RO:0002345
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","direct_ancestors":[{"relation_name":"is_a","term_name":"transports","termid":"RO:0002020"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exports","termid":"RO:0002345"}


id: PATO:0001710
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"size","termid":"PATO:0000117"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3-D extent","synonyms":[{"name":"3D size","type":"exact"}],"termid":"PATO:0001710"}


id: PR:Q9UT04
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAP8A3.13c gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UT04"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein P8A3.13c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAP8A3.13c","synonyms":[{"name":"Spom972h-SPAP8A3.13c","type":"exact"}],"termid":"PR:Q9UT04"}


id: GO:0043228
data:
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id: PATO:0000921
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"1-D extent","termid":"PATO:0001708"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"width","synonyms":[{"name":"breadth","type":"related"}],"termid":"PATO:0000921"}


id: MONDO:1012842
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any progressive retinal atrophy that occurs in dogs due to a mutation in the IMPG2 gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"progressive retinal atrophy, dog","termid":"MONDO:1012226"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"progressive retinal atrophy, IMPG2-related, dog","secondary_identifiers":["OMIA:002289-9615"],"synonyms":[{"name":"PRA4","type":"exact"},{"name":"progressive retinal atrophy 4, dog","type":"related"}],"termid":"MONDO:1012842","xrefs":{"Monarch":{"xref_id":"1012842"}}}


id: MONDO:0017558
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital elbow dislocation","termid":"MONDO:0017469"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital elbow dislocation, unilateral","secondary_identifiers":["MEDGEN:1842743","icd11.foundation:1630272046","GARD:21223","UMLS:C5681091","Orphanet:295225"],"termid":"MONDO:0017558","xrefs":{"Monarch":{"xref_id":"0017558"}}}


id: FYPO:0000329
data:
  {"alleles_by_uniquename":{"SJAG_00610:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00610","name":"pck2delta","uniquename":"SJAG_00610:allele-1"},"SJAG_01787:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01787","name":"pck1delta","uniquename":"SJAG_01787:allele-1"},"SJAG_04551:allele-2":{"allele_type":"amino_acid_insertion","description":"82-NITCIYDLDIIINPYNFNEVYIYEE-105","gene_uniquename":"SJAG_04551","name":"Pmk1Sj(ins82-105)","uniquename":"SJAG_04551:allele-2"},"SJAG_04551:allele-4":{"allele_type":"partial_amino_acid_deletion","description":"Pmk1 from S. pombe with deleted residues 82-105","gene_uniquename":"SJAG_04551","name":"Pmk1Sp(delta82-105)","uniquename":"SJAG_04551:allele-4"},"SJAG_04697:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04697","name":"gms1delta","uniquename":"SJAG_04697:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[119822],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0002033"},{"annotations":[119818,119814],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0001838"},{"annotations":[119521],"is_not":false,"rel_names":["output_of"],"summary":null,"term":"FYPO:0003727"},{"annotations":[119808],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0001038"}]},"cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein metabolic process during vegetative growth","termid":"FYPO:0000328"},{"relation_name":"is_a","term_name":"abnormal protein modification","termid":"FYPO:0002494"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00610":null,"SJAG_01787":null,"SJAG_04551":null,"SJAG_04697":null},"genotype_count":5,"genotypes_by_uniquename":{"Pmk1Sj(ins82-105)-82-NITCIYDLDIIINPYNFNEVYIYEE-105-amino_acid_insertion-expression-not_assayed_or_wild_type":{"display_name":"Pmk1Sj(ins82-105)(82-NITCIYDLDIIINPYNFNEVYIYEE-105)","display_uniquename":"Pmk1Sj(ins82-105)-82-NITCIYDLDIIINPYNFNEVYIYEE-105-amino_acid_insertion-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04551:allele-2","expression":"Not assayed or wild type"}]}]},"Pmk1Sp(delta82-105)-Pmk1_from_S._pombe_with_deleted_residues_82-105-partial_amino_acid_deletion-expression-not_assayed_or_wild_type":{"display_name":"Pmk1Sp(delta82-105)(Pmk1 from S. pombe with deleted residues 82-105 Δaa)","display_uniquename":"Pmk1Sp(delta82-105)-Pmk1_from_S._pombe_with_deleted_residues_82-105-partial_amino_acid_deletion-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04551:allele-4","expression":"Not assayed or wild type"}]}]},"gms1delta":{"display_name":"gms1delta","display_uniquename":"gms1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04697:allele-1","expression":"Null"}]}]},"pck1delta":{"display_name":"pck1delta","display_uniquename":"pck1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01787:allele-1","expression":"Null"}]}]},"pck2delta":{"display_name":"pck2delta","display_uniquename":"pck2delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00610:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002494","FYPO:0001320","FYPO:0001985","FYPO:0002274","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"abnormal protein modification during vegetative growth","references_by_uniquename":{"PMID:34198697":null,"PMID:36058798":null},"single_locus_annotated_genes":["SJAG_01787","SJAG_04551","SJAG_04697","SJAG_00610"],"single_locus_genotype_uniquenames":["Pmk1Sp(delta82-105)-Pmk1_from_S._pombe_with_deleted_residues_82-105-partial_amino_acid_deletion-expression-not_assayed_or_wild_type","pck1delta","Pmk1Sj(ins82-105)-82-NITCIYDLDIIINPYNFNEVYIYEE-105-amino_acid_insertion-expression-not_assayed_or_wild_type","pck2delta","gms1delta"],"synonyms":[{"name":"abnormal protein modification during mitotic cell cycle","type":"related"},{"name":"abnormal protein/peptide modification during vegetative growth","type":"exact"}],"termid":"FYPO:0000329","terms_by_termid":{"FYPO:0001038":null,"FYPO:0001838":null,"FYPO:0002033":null,"FYPO:0003727":null,"FYPO_EXT:0000001":null}}


id: MONDO:0022770
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"circumscribed cutaneous aplasia of the vertex","termid":"MONDO:0022770","xrefs":{"Monarch":{"xref_id":"0022770"}}}


id: MONDO:0002295
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A glomus tumor arising from the skin. It usually presents as a small red-blue nodule and it often associated with pain at the site.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"skin cancer","termid":"MONDO:0002898"},{"relation_name":"is_a","term_name":"dermis tumor","termid":"MONDO:0002300"},{"relation_name":"is_a","term_name":"glomus tumor","termid":"MONDO:0018327"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"skin glomus tumor","secondary_identifiers":["DOID:2430","MEDGEN:87537","SCTID:254795008","NCIT:C4491","UMLS:C0346083"],"synonyms":[{"name":"glomus neoplasm of skin","type":"exact"},{"name":"glomus neoplasm of the skin","type":"exact"},{"name":"glomus skin neoplasm","type":"exact"},{"name":"glomus skin tumor","type":"exact"},{"name":"glomus skin tumour","type":"exact"},{"name":"glomus tumor of skin","type":"exact"},{"name":"glomus tumor of the skin","type":"exact"},{"name":"glomus tumour of skin","type":"exact"},{"name":"glomus tumour of the skin","type":"exact"},{"name":"skin glomus neoplasm","type":"exact"},{"name":"zone of skin glomus tumor","type":"exact"},{"name":"zone of skin glomus tumour","type":"exact"}],"termid":"MONDO:0002295","xrefs":{"Monarch":{"xref_id":"0002295"}}}


id: PBO:0076845
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"telomerase reverse transcriptase","termid":"PBO:0076845"}


id: GO:1905405
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cohesin loading.","definition_xrefs":["PMID:26687354","GO_REF:0000058","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of mitotic cohesin loading (obsolete GO:1905405)","termid":"GO:1905405"}


id: MONDO:1012496
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Dahlem dwarfism, non-human animal","termid":"MONDO:1011969"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dahlem dwarfism, rabbit","secondary_identifiers":["OMIA:001998-9986"],"termid":"MONDO:1012496","xrefs":{"Monarch":{"xref_id":"1012496"}}}


id: PR:Q09680
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC5H10.12c gene.","definition_xrefs":["UniProtKB:Q09680","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C5H10.12c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC5H10.12c","synonyms":[{"name":"Spom972h-SPAC5H10.12c","type":"exact"}],"termid":"PR:Q09680"}


id: PATO:0001876
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A concave 3-D shape quality inhering in a bearer by virtue of the bearer's having two parts, roughly spherical and of equal size, connected by a bar.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"concave 3-D shape","termid":"PATO:0002008"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dumbbell-shaped","termid":"PATO:0001876"}


id: MONDO:1011925
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system disorder, non-human animal","termid":"MONDO:0700104"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"},{"relation_name":"is_a","term_name":"syndromic disease, non-human animal","termid":"MONDO:1011360"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"primary ciliary dyskinesia, non-human animal","secondary_identifiers":["OMIA:000573"],"termid":"MONDO:1011925","xrefs":{"Monarch":{"xref_id":"1011925"}}}


id: PBO:0044923
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DiGeorge syndrome critical region gene 11","termid":"PBO:0044923"}


id: PBO:0041779
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calpain small subunit 2","termid":"PBO:0041779"}


id: PBO:0040251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy related 7","termid":"PBO:0040251"}


id: MONDO:0014634
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"46,XY complete gonadal dysgenesis","termid":"MONDO:0010765"},{"relation_name":"is_a","term_name":"46,XY partial gonadal dysgenesis","termid":"MONDO:0016674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"46,XY sex reversal 10","secondary_identifiers":["UMLS:C4225331","MEDGEN:897538","DOID:0111775","GARD:16109","OMIM:616425"],"synonyms":[{"name":"46,XY SEX reversal 10","type":"related"},{"name":"46,XY Sex reversal type 10","type":"exact"},{"name":"46,XY sex reversal 10","type":"exact"},{"name":"46XY sex reversal 10","type":"exact"},{"name":"SRXY10","type":"related"},{"name":"chromosome 17Q24 deletion syndrome","type":"related"}],"termid":"MONDO:0014634","xrefs":{"Monarch":{"xref_id":"0014634"}}}


id: PATO:0000634
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A spatial pattern inhering in a bearer by virtue of the bearer's involvement of only one part or side.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spatial pattern","termid":"PATO:0000060"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unilateral","termid":"PATO:0000634"}


id: PBO:0077245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane and coiled-coil domains 5B (pseudogene)","termid":"PBO:0077245"}


id: PBO:0055265
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2692","termid":"PBO:0055265"}


id: GO:0071851
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.","definition_xrefs":["GOC:vw"],"gene_count":0,"genotype_count":0,"name":"obsolete mitotic G1 cell cycle arrest in response to nitrogen starvation (obsolete GO:0071851)","synonyms":[{"name":"G1 mitotic cell cycle arrest in response to nitrogen starvation","type":"exact"}],"termid":"GO:0071851"}


id: PBO:0053464
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 426","termid":"PBO:0053464"}


id: GO:0050898
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.","definition_xrefs":["PMID:18987211"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic process","termid":"GO:0008152"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"nitrile metabolic process","synonyms":[{"name":"nitrile metabolism","type":"exact"}],"termid":"GO:0050898"}


id: MONDO:0016687
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare variant of diffuse astrocytoma. It is predominantly composed of neoplastic astrocytes showing a small cell body with few, flaccid processes with a low content of glial filaments and scant GFAP expression. This lesion is not well defined and is considered by some authors as an occasional histopathological feature rather than a reproducibly identifiable variant. When occurring in children, this neoplasm may be difficult to separate from pilocytic juvenile astrocytoma. (Adapted from WHO)","definition_xrefs":["NCIT:C4320"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diffuse astrocytoma","termid":"MONDO:0016686"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protoplasmic astrocytoma","secondary_identifiers":["GARD:20707","UMLS:C0334580","DOID:7008","ICDO:9410/3","Orphanet:251598","MEDGEN:87268"],"synonyms":[{"name":"protoplasmic astrocytic tumor","type":"exact"},{"name":"protoplasmic astrocytic tumour","type":"exact"},{"name":"protoplasmic astrocytoma","type":"exact"},{"name":"protoplasmic astrocytoma (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0016687","xrefs":{"Monarch":{"xref_id":"0016687"}}}


id: GO:0034160
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.","definition_xrefs":["GOC:add","PMID:16551253","PMID:17328678"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of toll-like receptor 8 signaling pathway","termid":"GO:0034159"},{"relation_name":"is_a","term_name":"negative regulation of cytoplasmic pattern recognition receptor signaling pathway","termid":"GO:0039532"},{"relation_name":"negatively_regulates","term_name":"toll-like receptor 8 signaling pathway","termid":"GO:0034158"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of toll-like receptor 8 signaling pathway","synonyms":[{"name":"negative regulation of TLR8 signaling pathway","type":"exact"},{"name":"negative regulation of toll-like receptor 8 signalling pathway","type":"exact"}],"termid":"GO:0034160"}


id: PBO:0042179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin B1","termid":"PBO:0042179"}


id: MONDO:0019299
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete unclassified genetic skin disorder (obsolete MONDO:0019299)","secondary_identifiers":["Orphanet:79385"],"termid":"MONDO:0019299","xrefs":{"Monarch":{"xref_id":"0019299"}}}


id: PBO:0049364
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"general transcription factor IIi pseudogene 23","termid":"PBO:0049364"}


id: MONDO:0060688
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperthyroxinemia, euthyroid, caused by generalized 5-prime-deiodinase deficiency","secondary_identifiers":["MEDGEN:326643","OMIM:617953","UMLS:C1840059"],"synonyms":[{"name":"hyperthyroxinemia, euthyroid, caused by generalized 5-prime-deiodinase deficiency","type":"exact"},{"name":"hyperthyroxinemia, euthyroid, due to decreased peripheral conversion of T4","type":"related"}],"termid":"MONDO:0060688","xrefs":{"Monarch":{"xref_id":"0060688"}}}


id: PBO:0061523
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NSFL1 cofactor","termid":"PBO:0061523"}


id: PBO:0086191
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication","termid":"PBO:0086191"}


id: PBO:0046212
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"elongin C pseudogene 5","termid":"PBO:0046212"}


id: MONDO:0023180
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"fragile X syndrome","termid":"MONDO:0010383"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile X syndrome type 3","termid":"MONDO:0023180","xrefs":{"Monarch":{"xref_id":"0023180"}}}


id: PBO:0038816
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADAM metallopeptidase domain 20 pseudogene 3","termid":"PBO:0038816"}


id: PBO:0036173
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_histone_H2A_phosphorylation_during_vegetative_growth","termid":"PBO:0036173"}


id: MONDO:1010784
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pyoderma that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyoderma, non-human animal","termid":"MONDO:1010142"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyoderma, dog","secondary_identifiers":["OMIA:001877-9615"],"termid":"MONDO:1010784","xrefs":{"Monarch":{"xref_id":"1010784"}}}


id: MONDO:1012261
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"stringhalt, non-human animal","termid":"MONDO:1011631"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stringhalt, horse","secondary_identifiers":["OMIA:000950-9796"],"termid":"MONDO:1012261","xrefs":{"Monarch":{"xref_id":"1012261"}}}


id: PBO:0044804
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 104A","termid":"PBO:0044804"}


id: MONDO:0700024
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Chromosomal disorder in which chromosome 19 is affected.","definition_xrefs":["MONDO:patterns/chromosome_type"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal anomaly","termid":"MONDO:0020049"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 19 disorder","termid":"MONDO:0700024","xrefs":{"Monarch":{"xref_id":"0700024"}}}


id: MONDO:0005519
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma arising in the renal pelvis. The majority of renal pelvis carcinomas are transitional cell and less frequently squamous cell carcinomas.","definition_xrefs":["EFO:0005582"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal carcinoma","termid":"MONDO:0005206"},{"relation_name":"is_a","term_name":"malignant renal pelvis neoplasm","termid":"MONDO:0044919"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240","MONDO:0004992"],"is_obsolete":false,"name":"renal pelvis carcinoma","secondary_identifiers":["UMLS:C1335749","ICD10CM:C65","DOID:4919","ICD9:189.1","NCIT:C6142","MEDGEN:235548","SCTID:363457009"],"synonyms":[{"name":"cancer of renal pelvis","type":"broad"},{"name":"carcinoma of kidney pelvis","type":"exact"},{"name":"carcinoma of renal pelvis","type":"exact"},{"name":"carcinoma of the kidney pelvis","type":"exact"},{"name":"carcinoma of the renal pelvis","type":"exact"},{"name":"kidney pelvis carcinoma","type":"exact"},{"name":"kidney renal pelvis cancer","type":"exact"},{"name":"malignant neoplasm of renal pelvis","type":"broad"},{"name":"malignant renal pelvis neoplasm","type":"broad"},{"name":"malignant tumour of renal pelvis","type":"broad"},{"name":"renal pelvis cancer","type":"broad"},{"name":"renal pelvis carcinoma","type":"exact"}],"termid":"MONDO:0005519","xrefs":{"Monarch":{"xref_id":"0005519"}}}


id: MONDO:0005494
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An invasive breast carcinoma which is negative for expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2).","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"progesterone-receptor negative breast cancer","termid":"MONDO:0000616"},{"relation_name":"is_a","term_name":"Her2-receptor negative breast cancer","termid":"MONDO:0000618"},{"relation_name":"is_a","term_name":"estrogen-receptor negative breast cancer","termid":"MONDO:0006513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"triple-negative breast carcinoma","secondary_identifiers":["MEDGEN:1649548","SCTID:706970001","UMLS:C4722518","NCIT:C71732","DOID:0060081","EFO:0005537","MESH:D064726"],"synonyms":[{"name":"triple-negative breast cancer","type":"exact"},{"name":"triple-negative breast carcinoma","type":"exact"},{"name":"triple-receptor negative breast cancer","type":"exact"}],"termid":"MONDO:0005494","xrefs":{"Monarch":{"xref_id":"0005494"}}}


id: PBO:0079488
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thioredoxin domain containing 8","termid":"PBO:0079488"}


id: GO:0052163
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete symbiont defense to host-produced nitric oxide (obsolete GO:0052163)","synonyms":[{"name":"defense response to host innate immune response nitric oxide production","type":"narrow"},{"name":"evasion or tolerance by organism of host NO","type":"exact"},{"name":"evasion or tolerance by organism of host nitric oxide","type":"exact"},{"name":"evasion or tolerance by organism of host-produced NO","type":"exact"},{"name":"evasion or tolerance by organism of host-produced nitric oxide","type":"exact"},{"name":"evasion or tolerance by organism of nitric oxide produced by other organism involved in symbiotic interaction","type":"broad"},{"name":"evasion or tolerance by symbiont of host-produced nitric oxide","type":"exact"},{"name":"evasion or tolerance of NO produced by host in response to organism","type":"exact"},{"name":"evasion or tolerance of nitric oxide produced by host in response to organism","type":"exact"},{"name":"modulation by organism of defense-related host NO production","type":"exact"},{"name":"modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction","type":"broad"},{"name":"modulation by symbiont of defense-related host nitric oxide production","type":"related"},{"name":"response to defense-related host nitric oxide production","type":"related"},{"name":"response to defense-related nitric oxide production by other organism involved in symbiotic interaction","type":"broad"}],"termid":"GO:0052163"}


id: PBO:0043054
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcineurin like EF-hand protein 2","termid":"PBO:0043054"}


id: PBO:0086251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein that negatively regulates mitotic exit; forms a complex with Kel1p and Bud14p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel1p, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate","termid":"PBO:0086251"}


id: PBO:0086130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein required for initiation of G0 program; prevents degradation of nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway; phosphorylated by Rim15p; GFP protein localizes to the cytoplasm and nucleus; IGO1 has a paralog, IGO2, that arose from the whole genome duplication","termid":"PBO:0086130"}


id: PATO:0000799
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000799 muscle elevation value (obsolete PATO:0000799)","termid":"PATO:0000799"}


id: PBO:0017589
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy associated beclin family protein Atg6","termid":"PBO:0017589"}


id: GO:0015666
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA endonuclease activity","termid":"GO:0004520"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140097"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0140097","GO:0003824"],"is_obsolete":false,"name":"restriction endodeoxyribonuclease activity","synonyms":[{"name":"restriction endonuclease activity","type":"exact"},{"name":"restriction enzyme activity","type":"exact"}],"termid":"GO:0015666"}


id: GO:0035563
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.","definition_xrefs":["GOC:bf","PMID:20404130"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of binding","termid":"GO:0051099"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of chromatin binding","termid":"GO:0035563"}


id: PBO:0057817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3137","termid":"PBO:0057817"}


id: GO:0035194
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.","definition_xrefs":["PMID:15066275","PMID:11713190","GOC:ems","PMID:18771919","PMID:33184244","PMID:15020054","PMID:32885814","PMID:11201747"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-transcriptional gene silencing","termid":"GO:0016441"},{"relation_name":"is_a","term_name":"regulatory ncRNA-mediated gene silencing","termid":"GO:0031047"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulatory ncRNA-mediated post-transcriptional gene silencing","secondary_identifiers":["Reactome:R-HSA-426496","Wikipedia:RNA_interference","GO:0016246"],"synonyms":[{"name":"PTGS","type":"broad"},{"name":"RNA interference","type":"broad"},{"name":"RNA-dependent post-transcriptional gene silencing","type":"exact"},{"name":"RNA-mediated post-transcriptional gene silencing","type":"exact"},{"name":"RNA-mediated posttranscriptional gene silencing","type":"exact"},{"name":"RNAi","type":"broad"},{"name":"cosuppression","type":"related"},{"name":"ncRNA-mediated post-transcriptional gene silencing","type":"exact"},{"name":"post-transcriptional gene silencing by RNA","type":"related"},{"name":"posttranscriptional gene silencing by RNA","type":"exact"},{"name":"quelling","type":"related"}],"termid":"GO:0035194"}


id: PBO:0040637
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brain abundant membrane attached signal protein 1","termid":"PBO:0040637"}


id: GO:0060628
data:
  {"annotated_genes":["SJAG_01166"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[77003],"is_not":false,"summary":null,"term":"GO:0060628"}]},"cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of intracellular transport","termid":"GO:0032386"},{"relation_name":"is_a","term_name":"regulation of vesicle-mediated transport","termid":"GO:0060627"},{"relation_name":"regulates","term_name":"endoplasmic reticulum to Golgi vesicle-mediated transport","termid":"GO:0006888"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01166":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0016192","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of ER to Golgi vesicle-mediated transport","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0060628","terms_by_termid":{"GO:0060628":null}}


id: GO:0034800
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.","definition_xrefs":["UM-BBD_reactionID:r1067"],"gene_count":0,"genotype_count":0,"name":"obsolete trinitrophenol dihydride denitratase activity (obsolete GO:0034800)","synonyms":[{"name":"TNP dihydride denitratase activity","type":"exact"},{"name":"2,4,6-trinitrophenol dihydride denitratase activity","type":"exact"}],"termid":"GO:0034800"}


id: MONDO:0009257
data:
  {"annotated_genes":["SJAG_02951","SJAG_01784","SJAG_03818"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86400,86401,86402],"is_not":false,"summary":null,"term":"MONDO:0009257"}]},"cv_name":"mondo","definition":"Galactose epimerase deficiency is a very rare, moderate to severe form of galactosemia characterized by moderate to severe signs of impaired galactose metabolism.","definition_xrefs":["Orphanet:79238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"galactosemia","termid":"MONDO:0018116"}],"gene_count":3,"genes_by_uniquename":{"SJAG_01784":null,"SJAG_02951":null,"SJAG_03818":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0037792","MONDO:0005328"],"is_obsolete":false,"name":"galactose epimerase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["SCTID:8849004","GARD:5392","UMLS:C0751161","MEDGEN:199598","DOID:0111458","NANDO:2200534","OMIM:230350"],"synonyms":[{"name":"GALE deficiency","type":"exact"},{"name":"GALE-D","type":"exact"},{"name":"Gale deficiency","type":"related"},{"name":"UDP-galactose-4-epimerase deficiency","type":"exact"},{"name":"epimerase deficiency galactosemia","type":"exact"},{"name":"galactose epimerase deficiency","type":"exact"},{"name":"galactosemia 3","type":"related"},{"name":"galactosemia type 3","type":"exact"},{"name":"uridine diphosphate galactose-4-epimerase deficiency","type":"exact"}],"termid":"MONDO:0009257","terms_by_termid":{"MONDO:0009257":null},"xrefs":{"Monarch":{"xref_id":"0009257"}}}


id: PBO:0088576
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III complex subunit Rpc82","termid":"PBO:0088576"}


id: PBO:0045000
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dicer 1, ribonuclease III","termid":"PBO:0045000"}


id: PBO:0018127
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Coffin-Lowry Syndrome","termid":"PBO:0018127"}


id: PBO:0004315
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.5.1.48","termid":"PBO:0004315"}


id: PBO:0000672
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"queuine tRNA-ribosyltransferase (predicted)","termid":"PBO:0000672"}


id: PBO:0111944
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAZ domain","termid":"PBO:0111944"}


id: GO:1902072
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.","definition_xrefs":["GOC:TermGenie","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cellular response to hypoxia","termid":"GO:1900038"},{"relation_name":"is_a","term_name":"regulation of hypoxia-inducible factor-1alpha signaling pathway","termid":"GO:1902071"},{"relation_name":"is_a","term_name":"negative regulation of intracellular signal transduction","termid":"GO:1902532"},{"relation_name":"negatively_regulates","term_name":"hypoxia-inducible factor-1alpha signaling pathway","termid":"GO:0097411"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of hypoxia-inducible factor-1alpha signaling pathway","synonyms":[{"name":"down regulation of HIF1alpha pathway","type":"exact"},{"name":"down regulation of hypoxia-inducible factor-1alpha signaling pathway","type":"exact"},{"name":"down regulation of hypoxia-inducible factor-1alpha signalling pathway","type":"exact"},{"name":"down-regulation of HIF1alpha pathway","type":"exact"},{"name":"down-regulation of hypoxia-inducible factor-1alpha signaling pathway","type":"exact"},{"name":"down-regulation of hypoxia-inducible factor-1alpha signalling pathway","type":"exact"},{"name":"downregulation of HIF1alpha pathway","type":"exact"},{"name":"downregulation of hypoxia-inducible factor-1alpha signaling pathway","type":"exact"},{"name":"downregulation of hypoxia-inducible factor-1alpha signalling pathway","type":"exact"},{"name":"inhibition of HIF1alpha pathway","type":"exact"},{"name":"inhibition of hypoxia-inducible factor-1alpha signaling pathway","type":"narrow"},{"name":"inhibition of hypoxia-inducible factor-1alpha signalling pathway","type":"exact"},{"name":"negative regulation of HIF1alpha pathway","type":"exact"},{"name":"negative regulation of hypoxia-inducible factor-1alpha signalling pathway","type":"exact"}],"termid":"GO:1902072"}


id: PBO:0072160
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S15a pseudogene 37","termid":"PBO:0072160"}


id: PBO:0083966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GID Complex subunit, serves as adaptor for regulatory subunit Vid24p; protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm","termid":"PBO:0083966"}


id: FYPO:0001384
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which a protein kinase activity is absent.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished catalytic activity","termid":"FYPO:0000664"},{"relation_name":"is_a","term_name":"abnormal protein kinase activity","termid":"FYPO:0001381"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000654","FYPO:0000661","FYPO:0000707","FYPO:0000652"],"is_obsolete":false,"name":"abolished protein kinase activity","synonyms":[{"name":"protein kinase activity abolished","type":"exact"}],"termid":"FYPO:0001384"}


id: MONDO:0700184
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A T-cell leukemia in which there is a persistent increase in the number of large granular lymphocytes in the peripheral blood and occurring in a cat.","definition_xrefs":["NCIT:C135724"],"direct_ancestors":[{"relation_name":"is_a","term_name":"feline neoplasm","termid":"MONDO:0700175"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"feline large granular lymphocyte lymphoma","termid":"MONDO:0700184","xrefs":{"Monarch":{"xref_id":"0700184"}}}


id: MOD:00094
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-cysteine residue to L-cysteine amide.","definition_xrefs":["PubMed:1892838","PubMed:7149738","RESID:AA0085"],"direct_ancestors":[{"relation_name":"is_a","term_name":"C1-amidated residue","termid":"MOD:00883"},{"relation_name":"is_a","term_name":"modified L-cysteine residue","termid":"MOD:00905"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"L-cysteine amide","synonyms":[{"name":"(2R)-2-amino-3-sulfanylpropanamide","type":"exact"},{"name":"2-amino-3-mercaptopropanamide","type":"exact"},{"name":"CysN","type":"exact"},{"name":"L-cysteine amide","type":"exact"},{"name":"MOD_RES Cysteine amide","type":"exact"},{"name":"amidated L-cysteine","type":"exact"},{"name":"cysteinamide","type":"exact"}],"termid":"MOD:00094"}


id: PBO:0011496
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Bin3 family, methyltransferase (predicted)","termid":"PBO:0011496"}


id: MONDO:0011549
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hypotrichosis in which the cause of the disease is a mutation in the APCDD1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypotrichosis","termid":"MONDO:0003037"},{"relation_name":"is_a","term_name":"hypotrichosis simplex","termid":"MONDO:0018914"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypotrichosis 1","secondary_identifiers":["DOID:0110698","OMIM:605389","UMLS:C4551976","MEDGEN:1644234"],"synonyms":[{"name":"APCDD1 hypotrichosis","type":"exact"},{"name":"HHS","type":"broad"},{"name":"HTS","type":"exact"},{"name":"HYPT1","type":"exact"},{"name":"hereditary generalised hypotrichosis simplex","type":"exact"},{"name":"hereditary generalized hypotrichosis simplex","type":"exact"},{"name":"hypotrichosis 1","type":"exact"},{"name":"hypotrichosis caused by mutation in APCDD1","type":"exact"},{"name":"hypotrichosis simplex, generalized, hereditary","type":"related"},{"name":"hypotrichosis type 1","type":"exact"}],"termid":"MONDO:0011549","xrefs":{"Monarch":{"xref_id":"0011549"}}}


id: GO:0090015
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.","definition_xrefs":["GOC:tb","GOC:sdb_2009","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"auxin-activated signaling pathway","termid":"GO:0009734"},{"relation_name":"is_a","term_name":"regulation of leaflet formation","termid":"GO:0090016"},{"relation_name":"is_a","term_name":"positive regulation of leaf development","termid":"GO:1905623"},{"relation_name":"positively_regulates","term_name":"leaflet formation","termid":"GO:0090014"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of leaflet formation by auxin mediated signaling pathway","synonyms":[{"name":"positive regulation of leaflet formation by auxin mediated signalling pathway","type":"exact"}],"termid":"GO:0090015"}


id: GO:0110099
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.","definition_xrefs":["PMID:24085037","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of calcium import into the mitochondrion","termid":"GO:0110097"},{"relation_name":"is_a","term_name":"negative regulation of calcium ion transmembrane transport","termid":"GO:1903170"},{"relation_name":"negatively_regulates","term_name":"calcium import into the mitochondrion","termid":"GO:0036444"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0055085"],"is_obsolete":false,"name":"negative regulation of calcium import into the mitochondrion","termid":"GO:0110099"}


id: PBO:0004179
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-Pro dipeptidase (predicted)","termid":"PBO:0004179"}


id: GO:0019353
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.","definition_xrefs":["PMID:32976912"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protoporphyrinogen IX biosynthetic process","termid":"GO:0006782"},{"relation_name":"is_a","term_name":"tetrapyrrole biosynthetic process from glutamate","termid":"GO:0033526"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"part_of","termid":"GO:0033013"},{"rel_name":"is_a","termid":"GO:0033013"}],"interesting_parent_ids":["GO:0008150","GO:0006520","GO:0033013","GO:0044281"],"is_obsolete":false,"name":"protoporphyrinogen IX biosynthetic process from glutamate","synonyms":[{"name":"protoporphyrinogen IX anabolism from glutamate","type":"exact"},{"name":"protoporphyrinogen IX formation from glutamate","type":"exact"},{"name":"protoporphyrinogen IX synthesis from glutamate","type":"exact"}],"termid":"GO:0019353"}


id: MONDO:0014633
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An idiopathic generalized epilepsy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis. Affected individuals have cognitive regression and intellectual disability and that has material basis in heterozygous mutation in the SLC6A1 gene on chromosome 3p25.","definition_xrefs":["DOID:0060475"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"inborn disorder of amino acid transport","termid":"MONDO:0019216"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"},{"relation_name":"is_a","term_name":"childhood-onset epilepsy syndrome with developmental and/or epileptic encephalopathy","termid":"MONDO:0800500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"epilepsy with myoclonic atonic seizures","secondary_identifiers":["SCTID:230421008","GARD:16108","ICD9:345.10","UMLS:C0393702","OMIM:616421","Orphanet:1942","MEDGEN:98284","icd11.foundation:951920505"],"synonyms":[{"name":"Doose syndrome","type":"exact"},{"name":"EMAS","type":"exact"},{"name":"EMAtS","type":"exact"},{"name":"MAE","type":"exact"},{"name":"Myoclonic Atonic Epilepsy","type":"exact"},{"name":"epilepsy with myoclonic atonic seizures","type":"exact"},{"name":"epilepsy with myoclonic-astatic seizures","type":"exact"},{"name":"epilepsy with myoclonic-atonic seizures","type":"exact"},{"name":"epilepsy with myoclono-astatic crisis","type":"related"},{"name":"myoclonic astatic epilepsy","type":"related"},{"name":"myoclonic atonic epilepsy","type":"exact"},{"name":"myoclonic-astatic epilepsy in early childhood","type":"exact"},{"name":"myoclonic-atonic epilepsy","type":"exact"}],"termid":"MONDO:0014633","xrefs":{"Monarch":{"xref_id":"0014633"}}}


id: MONDO:0012768
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"prostate cancer, hereditary","termid":"MONDO:0700275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"prostate cancer, hereditary, 11","secondary_identifiers":["OMIM:611955","MESH:C567449","MEDGEN:394363","GARD:15536","UMLS:C2677773"],"synonyms":[{"name":"HPC11","type":"exact"},{"name":"prostate cancer, hereditary, 11","type":"exact"}],"termid":"MONDO:0012768","xrefs":{"Monarch":{"xref_id":"0012768"}}}


id: MONDO:0013017
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A hypotrichosis that has material basis in a mutation on chromosome 1p21.1-q21.3.","definition_xrefs":["PMID:16185270","DOID:0110702"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"Marie Unna hereditary hypotrichosis","termid":"MONDO:0018631"},{"relation_name":"is_a","term_name":"Marie Unna hereditary hypotrichosis","termid":"MONDO:0018631"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypotrichosis 5","secondary_identifiers":["OMIM:612841","UMLS:C2748535","GARD:15585","MEDGEN:440568","MESH:C567554"],"synonyms":[{"name":"HYPT5","type":"exact"},{"name":"MUHH2","type":"exact"},{"name":"Marie Unna hereditary hypotrichosis 2","type":"exact"},{"name":"Muhh2","type":"exact"},{"name":"hypotrichosis 5","type":"exact"},{"name":"hypotrichosis type 5","type":"exact"},{"name":"hypt5","type":"exact"}],"termid":"MONDO:0013017","xrefs":{"Monarch":{"xref_id":"0013017"}}}


id: PBO:0056597
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MDH1 pseudogene 2","termid":"PBO:0056597"}


id: MONDO:0015916
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete rare neuroinflammatory or neuroimmunological disease (obsolete MONDO:0015916)","secondary_identifiers":["Orphanet:182064"],"termid":"MONDO:0015916","xrefs":{"Monarch":{"xref_id":"0015916"}}}


id: PBO:0073986
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 25 member 1","termid":"PBO:0073986"}


id: PBO:0045329
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dedicator of cytokinesis 7","termid":"PBO:0045329"}


id: PBO:0061440
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor subfamily 2 group E member 3","termid":"PBO:0061440"}


id: PBO:0084518
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; required for respiratory growth; null mutant displays induction of the unfolded protein response; homologous to worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111","termid":"PBO:0084518"}


id: PBO:0039486
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain 20 family member A9, pseudogene","termid":"PBO:0039486"}


id: PBO:0073615
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SIDT1 antisense RNA 1","termid":"PBO:0073615"}


id: PBO:0046750
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exocyst complex component 5","termid":"PBO:0046750"}


id: PBO:0068701
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4 small nuclear 82, pseudogene","termid":"PBO:0068701"}


id: MONDO:0017632
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Any of the forms of liver and intrahepatic bile duct neoplasm that have a rare incidence.","definition_xrefs":["MONDO:patterns/rare"],"gene_count":0,"genotype_count":0,"name":"obsolete rare tumor of liver and intrahepatic biliary tract (obsolete MONDO:0017632)","secondary_identifiers":["Orphanet:306636"],"synonyms":[{"name":"rare liver and intrahepatic bile duct neoplasm","type":"exact"},{"name":"rare tumor of liver and IBT","type":"exact"}],"termid":"MONDO:0017632","xrefs":{"Monarch":{"xref_id":"0017632"}}}


id: MONDO:0012612
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0006025","MONDO:0005066"],"is_obsolete":false,"name":"intellectual disability, autosomal recessive 12","secondary_identifiers":["MESH:C567019","OMIM:611090","UMLS:C1970200","GARD:22540","MEDGEN:370850","DOID:0081180"],"synonyms":[{"name":"MRT12","type":"related"},{"name":"intellectual developmental disorder, autosomal recessive 12","type":"exact"},{"name":"intellectual disability, autosomal recessive 12","type":"exact"},{"name":"intellectual disability, autosomal recessive type 12","type":"exact"},{"name":"mental retardation, autosomal recessive 12","type":"related"},{"name":"mental retardation, autosomal recessive type 12","type":"exact"}],"termid":"MONDO:0012612","xrefs":{"Monarch":{"xref_id":"0012612"}}}


id: PBO:0071742
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L39 pseudogene 40","termid":"PBO:0071742"}


id: PBO:0075387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SP2 antisense RNA 1","termid":"PBO:0075387"}


id: PBO:0059051
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiosis specific nuclear structural 1","termid":"PBO:0059051"}


id: GO:0001811
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of type I hypersensitivity","termid":"GO:0001810"},{"relation_name":"is_a","term_name":"negative regulation of hypersensitivity","termid":"GO:0002884"},{"relation_name":"is_a","term_name":"negative regulation of immunoglobulin mediated immune response","termid":"GO:0002890"},{"relation_name":"negatively_regulates","term_name":"type I hypersensitivity","termid":"GO:0016068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of type I hypersensitivity","synonyms":[{"name":"down regulation of type I hypersensitivity","type":"exact"},{"name":"down-regulation of type I hypersensitivity","type":"exact"},{"name":"downregulation of type I hypersensitivity","type":"exact"},{"name":"inhibition of type I hypersensitivity","type":"narrow"}],"termid":"GO:0001811"}


id: PBO:0088014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Type II phosphatidylinositol 4-kinase; binds Las17p, a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization","termid":"PBO:0088014"}


id: GO:0004690
data:
  {"annotated_genes":["SJAG_04312"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73774],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004691"}]},"cv_name":"molecular_function","definition":"cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein serine/threonine kinase activity","termid":"GO:0004674"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04312":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0004672"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016301"}],"interesting_parent_ids":["GO:0016301","GO:0004672","GO:0003824","GO:0016740","GO:0003674","GO:0140096"],"is_obsolete":false,"name":"cyclic nucleotide-dependent protein kinase activity","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0004690","terms_by_termid":{"GO:0004691":null}}


id: GO:1901192
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of protein-containing complex assembly","termid":"GO:0031334"},{"relation_name":"is_a","term_name":"regulation of formation of translation initiation ternary complex","termid":"GO:1901190"},{"relation_name":"positively_regulates","term_name":"formation of translation initiation ternary complex","termid":"GO:0001677"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0065003"},{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"positive regulation of formation of translation initiation ternary complex","synonyms":[{"name":"activation of formation of translation initiation ternary complex","type":"narrow"},{"name":"activation of translation initiation ternary complex assembly","type":"exact"},{"name":"positive regulation of translation initiation ternary complex assembly","type":"exact"},{"name":"up regulation of formation of translation initiation ternary complex","type":"exact"},{"name":"up regulation of translation initiation ternary complex assembly","type":"exact"},{"name":"up-regulation of formation of translation initiation ternary complex","type":"exact"},{"name":"up-regulation of translation initiation ternary complex assembly","type":"exact"},{"name":"upregulation of formation of translation initiation ternary complex","type":"exact"},{"name":"upregulation of translation initiation ternary complex assembly","type":"exact"}],"termid":"GO:1901192"}


id: MONDO:0032654
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hyper-IgE syndrome","termid":"MONDO:0018037"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0005046"],"is_obsolete":false,"name":"hyper-IgE recurrent infection syndrome 3, autosomal recessive","secondary_identifiers":["UMLS:C4748969","DOID:0080595","OMIM:618282","MEDGEN:1648483"],"synonyms":[{"name":"HIES3","type":"related"},{"name":"HYPER-IgE RECURRENT INFECTION SYNDROME 3, AUTOSOMAL RECESSIVE","type":"related"}],"termid":"MONDO:0032654","xrefs":{"Monarch":{"xref_id":"0032654"}}}


id: GO:0045222
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.","definition_xrefs":["ISBN:0198506732","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete CD4 biosynthetic process (obsolete GO:0045222)","synonyms":[{"name":"CD4 anabolism","type":"exact"},{"name":"CD4 biosynthesis","type":"exact"},{"name":"CD4 formation","type":"exact"},{"name":"CD4 synthesis","type":"exact"}],"termid":"GO:0045222"}


id: GO:0016628
data:
  {"annotated_genes":["SJAG_00203","SJAG_02151","SJAG_01786","SJAG_04107","SJAG_03240","SJAG_04954","SJAG_04810","SJAG_02007","SJAG_01041","SJAG_03236","SJAG_01362","SJAG_00174","SJAG_04652","SJAG_02717","SJAG_03024"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[58759,67824],"is_not":false,"summary":null,"term":"GO:0016628"},{"annotations":[80677],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0050613"},{"annotations":[80687],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000246"},{"annotations":[59951],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004318"},{"annotations":[95378],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0141148"},{"annotations":[73464],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016156"},{"annotations":[118805,89820,105060,110010],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106414"},{"annotations":[61725],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0160198"},{"annotations":[61732],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102389"},{"annotations":[77167],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043115"},{"annotations":[79143],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008977"},{"annotations":[68161],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004665"},{"annotations":[111707],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019166"},{"annotations":[110011],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102262"},{"annotations":[110012],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102263"},{"annotations":[105061],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102264"},{"annotations":[118806],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102266"},{"annotations":[118807],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102267"},{"annotations":[66186],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0102265"}]},"cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.","definition_xrefs":["EC:1.3.1.-"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors","termid":"GO:0016627"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00174":null,"SJAG_00203":null,"SJAG_01041":null,"SJAG_01362":null,"SJAG_01786":null,"SJAG_02007":null,"SJAG_02151":null,"SJAG_02717":null,"SJAG_03024":null,"SJAG_03236":null,"SJAG_03240":null,"SJAG_04107":null,"SJAG_04652":null,"SJAG_04810":null,"SJAG_04954":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000003":null,"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-4419979","Reactome:R-HSA-4755572","Reactome:R-HSA-9661745","Reactome:R-HSA-9661726"],"termid":"GO:0016628","terms_by_termid":{"GO:0000246":null,"GO:0004318":null,"GO:0004665":null,"GO:0008977":null,"GO:0016156":null,"GO:0016628":null,"GO:0019166":null,"GO:0043115":null,"GO:0050613":null,"GO:0102262":null,"GO:0102263":null,"GO:0102264":null,"GO:0102265":null,"GO:0102266":null,"GO:0102267":null,"GO:0102389":null,"GO:0106414":null,"GO:0141148":null,"GO:0160198":null}}


id: PBO:0057223
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 379","termid":"PBO:0057223"}


id: GO:0046275
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catabolic process","termid":"GO:0009056"},{"relation_name":"is_a","term_name":"flavonoid metabolic process","termid":"GO:0009812"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"flavonoid catabolic process","synonyms":[{"name":"flavonoid breakdown","type":"exact"},{"name":"flavonoid catabolism","type":"exact"},{"name":"flavonoid degradation","type":"exact"}],"termid":"GO:0046275"}


id: PBO:0054101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1460","termid":"PBO:0054101"}


id: GO:0016436
data:
  {"annotated_genes":["SJAG_00722","SJAG_03008","SJAG_03332","SJAG_03773"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76303,79121,75985],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008650"},{"annotations":[80067],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070042"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.","definition_xrefs":["GOC:go-curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA methyltransferase activity","termid":"GO:0008649"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00722":null,"SJAG_03008":null,"SJAG_03332":null,"SJAG_03773":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0140098","GO:0016741","GO:0016740"],"is_obsolete":false,"name":"rRNA (uridine) methyltransferase activity","references_by_uniquename":{"GO_REF:0000033":null},"termid":"GO:0016436","terms_by_termid":{"GO:0008650":null,"GO:0070042":null}}


id: PBO:0005330
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA endoribonuclease involved in mRNP quality control (predicted)","termid":"PBO:0005330"}


id: GO:2000602
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of interphase of mitotic cell cycle.","definition_xrefs":["GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of interphase of mitotic cell cycle (obsolete GO:2000602)","synonyms":[{"name":"regulation of interphase of mitotic cell cycle","type":"exact"}],"termid":"GO:2000602"}


id: PBO:0039052
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"angiogenic factor with G-patch and FHA domains 1 pseudogene 1","termid":"PBO:0039052"}


id: FYPO:0003206
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to salt stress. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein-protein interaction","termid":"FYPO:0001645"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000702"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000707","FYPO:0000652","FYPO:0000702"],"is_obsolete":false,"name":"decreased protein-protein interaction during cellular response to salt stress","synonyms":[{"name":"decreased protein binding during cellular response to salt stress","type":"exact"},{"name":"decreased protein-protein interaction during salt stress","type":"exact"},{"name":"decreased protein-protein interaction in response to salt stress","type":"related"},{"name":"reduced protein-protein interaction during cellular response to salt stress","type":"exact"}],"termid":"FYPO:0003206"}


id: PBO:0084243
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle; HEH2 has a paralog, SRC1, that arose from the whole genome duplication","termid":"PBO:0084243"}


id: GO:0036454
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that has growth factor activity.","definition_xrefs":["GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"growth factor complex","termid":"GO:0036454"}


id: PBO:0045096
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DLX6 antisense RNA 1","termid":"PBO:0045096"}


id: PBO:0082702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the meiotic outer plaque of the spindle pole body; involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation","termid":"PBO:0082702"}


id: PBO:0046559
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group K member 1","termid":"PBO:0046559"}


id: MONDO:0019618
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An uncommon cause of hypopituitarism seen after severe postpartum hemorrhaging. Prolonged hypovolemia leads to ischemic necrosis of the pituitary. Clinical signs typically present in the puerperium and include failure to begin lactation, fatigue, hypotension and eventual amenorrhea. Clinical course is usually mild, however extreme cases may progress to adrenal failure. Prognosis is most favorable when hormone replacement is initiated soon after symptom onset.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sheehan syndrome","secondary_identifiers":["ICD10CM:E23.0","MESH:D007018","MEDGEN:116569","MedDRA:10036297","SCTID:290653008","SCTID:32390006","UMLS:C0242342","Orphanet:91355","icd11.foundation:421687193","NCIT:C35300","DOID:9476","GARD:7630"],"synonyms":[{"name":"Sheehan's syndrome","type":"exact"},{"name":"postpartum hypopituitarism","type":"exact"},{"name":"postpartum panhypopituitarism","type":"related"},{"name":"postpartum panhypopituitary syndrome","type":"related"},{"name":"postpartum pituitary necrosis","type":"related"}],"termid":"MONDO:0019618","xrefs":{"Monarch":{"xref_id":"0019618"}}}


id: MONDO:1011786
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease, non-human animal","termid":"MONDO:1011360"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"perinatal weak calf syndrome, non-human animal","secondary_identifiers":["OMIA:001817"],"termid":"MONDO:1011786","xrefs":{"Monarch":{"xref_id":"1011786"}}}


id: MONDO:0005940
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infections with viruses of the genus respirovirus, family paramyxoviridae. Host cell infection occurs by adsorption, via hemagglutinin, to the cell surface.","definition_xrefs":["MESH:D010253"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Paramyxoviridae infectious disease","termid":"MONDO:0005896"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"respirovirus infectious disease","secondary_identifiers":["MEDGEN:811417","UMLS:C3714630","EFO:0007465"],"synonyms":[{"name":"infections, Respirovirus","type":"related"}],"termid":"MONDO:0005940","xrefs":{"Monarch":{"xref_id":"0005940"}}}


id: PBO:0062316
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 6 subfamily B member 1","termid":"PBO:0062316"}


id: GO:1905296
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification.","definition_xrefs":["GO_REF:0000058","PMID:15073157","GOC:BHF","GOC:rl","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell fate specification","termid":"GO:0009996"},{"relation_name":"is_a","term_name":"negative regulation of neural crest formation","termid":"GO:0090301"},{"relation_name":"is_a","term_name":"negative regulation of neural crest cell differentiation","termid":"GO:1905293"},{"relation_name":"is_a","term_name":"regulation of neural crest cell fate specification","termid":"GO:1905295"},{"relation_name":"negatively_regulates","term_name":"neural crest cell fate specification","termid":"GO:0014036"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of neural crest cell fate specification","synonyms":[{"name":"down regulation of neural crest cell fate specification","type":"exact"},{"name":"down-regulation of neural crest cell fate specification","type":"exact"},{"name":"downregulation of neural crest cell fate specification","type":"exact"},{"name":"inhibition of neural crest cell fate specification","type":"narrow"}],"termid":"GO:1905296"}


id: GO:1900398
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of nucleotide biosynthetic process","termid":"GO:0030809"},{"relation_name":"is_a","term_name":"regulation of pyrimidine nucleotide biosynthetic process","termid":"GO:1900397"},{"relation_name":"negatively_regulates","term_name":"pyrimidine nucleotide biosynthetic process","termid":"GO:0006221"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0055086"},{"rel_name":"negatively_regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"negative regulation of pyrimidine nucleotide biosynthetic process","synonyms":[{"name":"down regulation of pyrimidine nucleotide anabolism","type":"exact"},{"name":"down regulation of pyrimidine nucleotide biosynthesis","type":"exact"},{"name":"down regulation of pyrimidine nucleotide biosynthetic process","type":"exact"},{"name":"down regulation of pyrimidine nucleotide formation","type":"exact"},{"name":"down regulation of pyrimidine nucleotide synthesis","type":"exact"},{"name":"down-regulation of pyrimidine nucleotide anabolism","type":"exact"},{"name":"down-regulation of pyrimidine nucleotide biosynthesis","type":"exact"},{"name":"down-regulation of pyrimidine nucleotide biosynthetic process","type":"exact"},{"name":"down-regulation of pyrimidine nucleotide formation","type":"exact"},{"name":"down-regulation of pyrimidine nucleotide synthesis","type":"exact"},{"name":"downregulation of pyrimidine nucleotide anabolism","type":"exact"},{"name":"downregulation of pyrimidine nucleotide biosynthesis","type":"exact"},{"name":"downregulation of pyrimidine nucleotide biosynthetic process","type":"exact"},{"name":"downregulation of pyrimidine nucleotide formation","type":"exact"},{"name":"downregulation of pyrimidine nucleotide synthesis","type":"exact"},{"name":"inhibition of pyrimidine nucleotide anabolism","type":"exact"},{"name":"inhibition of pyrimidine nucleotide biosynthesis","type":"exact"},{"name":"inhibition of pyrimidine nucleotide biosynthetic process","type":"narrow"},{"name":"inhibition of pyrimidine nucleotide formation","type":"exact"},{"name":"inhibition of pyrimidine nucleotide synthesis","type":"exact"},{"name":"negative regulation of pyrimidine nucleotide anabolism","type":"exact"},{"name":"negative regulation of pyrimidine nucleotide biosynthesis","type":"exact"},{"name":"negative regulation of pyrimidine nucleotide formation","type":"exact"},{"name":"negative regulation of pyrimidine nucleotide synthesis","type":"exact"}],"termid":"GO:1900398"}


id: PBO:0062092
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily A member 42 pseudogene","termid":"PBO:0062092"}


id: GO:0048721
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the clypeus are generated and organized.","definition_xrefs":["GOC:rc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-embryonic animal morphogenesis","termid":"GO:0009886"},{"relation_name":"part_of","term_name":"clypeo-labral disc morphogenesis","termid":"GO:0007453"},{"relation_name":"part_of","term_name":"clypeus development","termid":"GO:0048723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"clypeus morphogenesis","termid":"GO:0048721"}


id: PBO:0090393
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clr6 histone deacetylase associated PHD finger protein Cph1","termid":"PBO:0090393"}


id: GO:1902033
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.","definition_xrefs":["GOC:TermGenie","PMID:23403623"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of stem cell proliferation","termid":"GO:0072091"},{"relation_name":"regulates","term_name":"hematopoietic stem cell proliferation","termid":"GO:0071425"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of hematopoietic stem cell proliferation","synonyms":[{"name":"regulation of hemopoietic stem cell proliferation","type":"exact"}],"termid":"GO:1902033"}


id: GO:1903898
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.","definition_xrefs":["GOC:bf","GOC:PARL","PMID:22013210","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of endoplasmic reticulum unfolded protein response","termid":"GO:1900102"},{"relation_name":"is_a","term_name":"regulation of PERK-mediated unfolded protein response","termid":"GO:1903897"},{"relation_name":"negatively_regulates","term_name":"PERK-mediated unfolded protein response","termid":"GO:0036499"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of PERK-mediated unfolded protein response","synonyms":[{"name":"down regulation of PERK branch of UPR","type":"exact"},{"name":"down regulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"down regulation of PERK-mediated unfolded protein response","type":"exact"},{"name":"down regulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"down regulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"down regulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"},{"name":"down-regulation of PERK branch of UPR","type":"exact"},{"name":"down-regulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"down-regulation of PERK-mediated unfolded protein response","type":"exact"},{"name":"down-regulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"down-regulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"down-regulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"},{"name":"downregulation of PERK branch of UPR","type":"exact"},{"name":"downregulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"downregulation of PERK-mediated unfolded protein response","type":"exact"},{"name":"downregulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"downregulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"downregulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"},{"name":"inhibition of PERK branch of UPR","type":"narrow"},{"name":"inhibition of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"inhibition of PERK-mediated unfolded protein response","type":"narrow"},{"name":"inhibition of PKR-like ER kinase signal transduction","type":"narrow"},{"name":"inhibition of UPR signaling by PERK stress sensor","type":"narrow"},{"name":"inhibition of endoplasmic reticulum unfolded protein response; PERK signaling","type":"narrow"},{"name":"negative regulation of EIF2AK3-mediated unfolded protein response","type":"related"},{"name":"negative regulation of PERK branch of UPR","type":"exact"},{"name":"negative regulation of PERK signaling in response to endoplasmic reticulum stress","type":"related"},{"name":"negative regulation of PKR-like ER kinase signal transduction","type":"exact"},{"name":"negative regulation of UPR signaling by PERK stress sensor","type":"exact"},{"name":"negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling","type":"exact"}],"termid":"GO:1903898"}


id: PBO:0035891
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_phosphatidylserine_externalization","termid":"PBO:0035891"}


id: FYPO:0000973
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to copper ions is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular response to chemical stimulus during vegetative growth","termid":"FYPO:0001318"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0000002","FYPO:0000298","FYPO:0001312"],"is_obsolete":false,"name":"normal cellular response to copper ion","synonyms":[{"name":"normal cellular response to copper","type":"exact"},{"name":"normal cellular response to copper ion during mitotic cell cycle","type":"related"},{"name":"normal cellular response to copper ion during vegetative growth","type":"exact"}],"termid":"FYPO:0000973"}


id: PBO:0080787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"XK related, Y-linked pseudogene 7","termid":"PBO:0080787"}


id: MONDO:0020397
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Parachute tricuspid valve is a rare congenital heart malformation defined as an insertion of the chordal apparatus into a single papillary muscle or a muscle group, making a pathognomonic 'pear' shape sign in the four-chamber echocardiographic view with the atrium forming the larger base of the pear and the leaflets the apex. Isolated parachute tricuspid valve may be asymptomatic or present with symptoms of tricuspid stenosis (diastolic inspiratory murmur, pulsation of jugular veins, hepatomegaly, edema, epigastric discomfort, right atrial enlargement, right ventricular hypertrophy, electrocardiography abnormalities). It may also be associated with other heart malformations and present with symptoms of the complex of malformations.","definition_xrefs":["Orphanet:99056"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital tricuspid malformation","termid":"MONDO:0020289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"parachute tricuspid valve","secondary_identifiers":["GARD:19624","MEDGEN:576478","UMLS:C0344755"],"termid":"MONDO:0020397","xrefs":{"Monarch":{"xref_id":"0020397"}}}


id: GO:0019049
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process in which a virus interferes with the ability of the host to mount a defense in response to its presence. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["ISBN:1555811272"],"gene_count":0,"genotype_count":0,"name":"obsolete virus-mediated perturbation of host defense response (obsolete GO:0019049)","secondary_identifiers":["Reactome:R-HSA-169131","Reactome:R-HSA-164944","Reactome:R-HSA-164938","Reactome:R-HSA-168305"],"synonyms":[{"name":"evasion of host defenses by virus","type":"narrow"},{"name":"mitigation of host antiviral defense response","type":"narrow"},{"name":"mitigation of host defenses by virus","type":"exact"},{"name":"perturbation of host defense response by virus","type":"exact"},{"name":"regulation by virus of antiviral response","type":"narrow"},{"name":"regulation of defense response to virus by virus","type":"exact"},{"name":"viral host defence evasion","type":"narrow"},{"name":"viral host defense evasion","type":"narrow"},{"name":"viral regulation of antiviral response","type":"exact"}],"termid":"GO:0019049"}


id: FYPO:0004629
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic DNA replication is normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal DNA replication","termid":"FYPO:0001133"},{"relation_name":"is_a","term_name":"normal mitotic cell cycle process","termid":"FYPO:0002741"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000257","FYPO:0000002","FYPO:0001312"],"is_obsolete":false,"name":"normal mitotic DNA replication","synonyms":[{"name":"normal DNA replication during mitotic cell cycle","type":"exact"},{"name":"normal DNA replication during vegetative growth","type":"exact"}],"termid":"FYPO:0004629"}


id: GO:0015466
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. An agent that can lyse the cell in which it is synthesized.","definition_xrefs":["GOC:ma"],"gene_count":0,"genotype_count":0,"name":"obsolete autolysin activity (obsolete GO:0015466)","synonyms":[{"name":"autolysin activity","type":"exact"}],"termid":"GO:0015466"}


id: PomGeneEx:0000009
data:
  {"annotated_genes":["SJAG_00118","SJAG_01143"],"annotation_feature_type":"gene","cv_annotations":{"qualitative_gene_expression":[{"annotations":[119563,119582],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"PomGeneEx:0000011"}]},"cv_name":"PomGeneExRNA","definition":"A qualifier that describes a level of RNA observed under a given set of conditions or at an indicated time.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene expression qualifier","termid":"PomGeneEx:0000001"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00118":null,"SJAG_01143":null},"genotype_count":0,"is_obsolete":false,"name":"RNA expression level","references_by_uniquename":{"PMID:25866389":null},"termid":"PomGeneEx:0000009","terms_by_termid":{"GO:0000087":null,"PomGeneEx:0000011":null}}


id: GO:0100059
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phenotypic switching.","definition_xrefs":["GOC:cjm","GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of phenotypic switching by transcription from RNA polymerase II promoter (obsolete GO:0100059)","termid":"GO:0100059"}


id: GO:0002627
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of antigen processing and presentation","termid":"GO:0002579"},{"relation_name":"is_a","term_name":"regulation of T cell antigen processing and presentation","termid":"GO:0002625"},{"relation_name":"is_a","term_name":"positive regulation of T cell mediated immunity","termid":"GO:0002711"},{"relation_name":"positively_regulates","term_name":"T cell antigen processing and presentation","termid":"GO:0002457"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of T cell antigen processing and presentation","synonyms":[{"name":"activation of T cell antigen processing and presentation","type":"narrow"},{"name":"positive regulation of T lymphocyte antigen processing and presentation","type":"exact"},{"name":"positive regulation of T-cell antigen processing and presentation","type":"exact"},{"name":"positive regulation of T-lymphocyte antigen processing and presentation","type":"exact"},{"name":"stimulation of T cell antigen processing and presentation","type":"narrow"},{"name":"up regulation of T cell antigen processing and presentation","type":"exact"},{"name":"up-regulation of T cell antigen processing and presentation","type":"exact"},{"name":"upregulation of T cell antigen processing and presentation","type":"exact"}],"termid":"GO:0002627"}


id: GO:0042332
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of a motile cell or organism in response to gravity.","definition_xrefs":["GOC:jid","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to gravity","termid":"GO:0009629"},{"relation_name":"is_a","term_name":"taxis","termid":"GO:0042330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"gravitaxis","secondary_identifiers":["GO:0048062"],"synonyms":[{"name":"geotactic behavior","type":"exact"},{"name":"geotactic behaviour","type":"exact"},{"name":"geotaxis","type":"exact"},{"name":"gravitactic behavior","type":"exact"},{"name":"gravitactic behaviour","type":"exact"},{"name":"taxis in response to gravitational stimulus","type":"exact"},{"name":"taxis in response to gravity","type":"exact"}],"termid":"GO:0042332"}


id: MONDO:0003335
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Polyneuropathy that is persistent or long-standing in nature.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyneuropathy","termid":"MONDO:0001824"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"chronic polyneuropathy","secondary_identifiers":["DOID:5221","MEDGEN:223911","NCIT:C36071","UMLS:C1167650"],"synonyms":[{"name":"polyneuropathy, chronic","type":"exact"}],"termid":"MONDO:0003335","xrefs":{"Monarch":{"xref_id":"0003335"}}}


id: PBO:0049847
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HEAT repeat containing 9","termid":"PBO:0049847"}


id: PBO:0080568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat and FYVE domain containing 3","termid":"PBO:0080568"}


id: PATO:0000843
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000843 relative auditory threshold value (obsolete PATO:0000843)","termid":"PATO:0000843"}


id: PBO:0085371
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Phosphotyrosine-specific protein phosphatase; major role in the pheromone adaptive response through dephosphorylation of the Fus3p MAPK with a minor role by Ptp2p and Msg5p; minor role in the inactivation of Hog1p MAPK during osmolarity sensing with major role by Ptp2p; dephosphorylates and regulates the localization of Hog1p; minor role in the cell wall integrity pathway through tyrosine dephosphorylation of the MAPK Slt2p while Ptp2p plays a major role; localizes to the cytoplasm","termid":"PBO:0085371"}


id: PBO:0090192
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER ubiquitin family protein","termid":"PBO:0090192"}


id: GO:0071468
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.","definition_xrefs":["Wikipedia:PH","GOC:mah","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to acidic pH","termid":"GO:0010447"},{"relation_name":"is_a","term_name":"cellular response to pH","termid":"GO:0071467"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to acidic pH","synonyms":[{"name":"cellular response to acidity","type":"broad"}],"termid":"GO:0071468"}


id: PBO:0110563
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eIF-5A-deoxyhypusine hydroxylase","termid":"PBO:0110563"}


id: PBO:0068298
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein 5","termid":"PBO:0068298"}


id: GO:0052771
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420.","definition_xrefs":["PMID:8536708","PMID:9352911","GOC:mengo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete coenzyme F390-G hydrolase activity (obsolete GO:0052771)","synonyms":[{"name":"8-hydroxyguanylylated-coenzyme F420 hydrolase activity","type":"exact"}],"termid":"GO:0052771"}


id: PBO:0028019
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_CAAX-protein_geranylgeranyltransferase_activity","termid":"PBO:0028019"}


id: FYPO:0005834
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached, is decreased. Transport of all proteins or a specific protein may be affected.","definition_xrefs":["GO:0099110","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein transport along microtubule to cell tip cortex during vegetative growth","termid":"FYPO:0005832"},{"relation_name":"is_a","term_name":"decreased protein transport along microtubule to cell tip during vegetative growth","termid":"FYPO:0005833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased protein transport along microtubule to cell tip cortex during vegetative growth","synonyms":[{"name":"decreased protein movement along microtubule to cell tip cortex during vegetative growth","type":"exact"},{"name":"decreased protein transport along microtubule to cell cortex of cell tip during vegetative growth","type":"exact"},{"name":"decreased protein transport along microtubule to cell tip cortex during mitotic cell cycle","type":"related"},{"name":"reduced protein transport along microtubule to cell tip cortex during vegetative growth","type":"exact"}],"termid":"FYPO:0005834"}


id: PBO:0086954
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Regulator of mitochondrial proline metabolism; tethered with Fmp32p to inner mitochondrial membrane in large hetero-oligomeric complex, abundance of which is regulated by proline; involved in mitochondrial proline homeostasis and cellular redox balance; null exhibits pronounced defect in proline utilization, and can be functionally complemented by expression of human homolog MCUR1","termid":"PBO:0086954"}


id: GO:1900467
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of cellular potassium ion homeostasis.","definition_xrefs":["GOC:dgf","GOC:TermGenie","PMID:20412803"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of cellular potassium ion homeostasis (obsolete GO:1900467)","synonyms":[{"name":"regulation of cellular potassium ion homeostasis","type":"exact"}],"termid":"GO:1900467"}


id: PBO:0058406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4776-1","termid":"PBO:0058406"}


id: PBO:0040787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"brain expressed X-linked 4","termid":"PBO:0040787"}


id: GO:0102539
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.","definition_xrefs":["GOC:pz","PMID:10627048"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity","secondary_identifiers":["MetaCyc:RXN-14769"],"termid":"GO:0102539"}


id: GO:0008692
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.","definition_xrefs":["EC:5.1.2.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"racemase and epimerase activity, acting on hydroxy acids and derivatives","termid":"GO:0016856"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016853","GO:0003674"],"is_obsolete":false,"name":"3-hydroxybutyryl-CoA epimerase activity","secondary_identifiers":["MetaCyc:OHBUTYRYL-COA-EPIM-RXN","RHEA:21760"],"synonyms":[{"name":"3-hydroxyacyl-CoA epimerase activity","type":"related"},{"name":"3-hydroxybutanoyl-CoA 3-epimerase activity","type":"related"},{"name":"3-hydroxybutyryl coenzyme A epimerase activity","type":"related"}],"termid":"GO:0008692"}


id: GO:1905861
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod.","definition_xrefs":["GOC:TermGenie","PMID:28074884","GO_REF:0000079"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component assembly","termid":"GO:0022607"},{"relation_name":"is_a","term_name":"supramolecular fiber organization","termid":"GO:0097435"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"intranuclear rod assembly","synonyms":[{"name":"intranuclear actin rod assembly","type":"exact"},{"name":"intranuclear actin rod formation","type":"exact"},{"name":"intranuclear rod formation","type":"exact"}],"termid":"GO:1905861"}


id: GO:0102562
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete hydroxyproline O-arbinofuranose transferase activity (obsolete GO:0102562)","termid":"GO:0102562"}


id: PATO:0001867
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A shape quality inhering in a bearer by virtue of it being a quadrilateral polygon in which all four angles are right angles.","definition_xrefs":["Wikipedia:http://en.wikipedia.org/wiki/Rectangular"],"direct_ancestors":[{"relation_name":"is_a","term_name":"parallelogram","termid":"PATO:0002317"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rectangular","secondary_identifiers":["Image:http\\://upload.wikimedia.org/wikipedia/en/e/ee/Shaperec.svg"],"termid":"PATO:0001867"}


id: PBO:0043686
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COTL1 pseudogene 2","termid":"PBO:0043686"}


id: PBO:0070344
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY4 pseudogene 17","termid":"PBO:0070344"}


id: PBO:0038323
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malacards_displayed_disease_name","termid":"PBO:0038323"}


id: PBO:0030390
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-protein_mislocalized_to_cytoplasm_during_cellular_response_to_hydrogen_peroxide","termid":"PBO:0030390"}


id: PATO:0000225
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000225 sensory function (obsolete PATO:0000225)","termid":"PATO:0000225"}


id: MONDO:0033644
data:
  {"annotated_genes":["SJAG_00983"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86143],"is_not":false,"summary":null,"term":"MONDO:0033644"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00983":null},"genotype_count":0,"is_obsolete":false,"name":"microcornea, rod-cone dystrophy, cataract, and posterior staphyloma 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:18383","OMIM:619082","MEDGEN:1755099","UMLS:C5436769"],"synonyms":[{"name":"MRCS1","type":"exact"}],"termid":"MONDO:0033644","terms_by_termid":{"MONDO:0033644":null},"xrefs":{"Monarch":{"xref_id":"0033644"}}}


id: PBO:0091546
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces pombe specific protein, expressed during meiotic cell cycle","termid":"PBO:0091546"}


id: PBO:0043237
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chloride voltage-gated channel Ka","termid":"PBO:0043237"}


id: PBO:0038897
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adhesion G protein-coupled receptor A3","termid":"PBO:0038897"}


id: GO:1903821
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any detection of stimulus that is involved in morphogenesis checkpoint.","definition_xrefs":["GOC:TermGenie","GOC:mtg_cell_cycle","GO_REF:0000060"],"gene_count":0,"genotype_count":0,"name":"obsolete detection of stimulus involved in morphogenesis checkpoint (obsolete GO:1903821)","synonyms":[{"name":"detection of stimulus involved in septin checkpoint","type":"related"},{"name":"perception of stimulus involved in morphogenesis checkpoint","type":"exact"},{"name":"perception of stimulus involved in septin checkpoint","type":"related"},{"name":"stimulus detection involved in morphogenesis checkpoint","type":"exact"},{"name":"stimulus detection involved in septin checkpoint","type":"related"},{"name":"stimulus sensing involved in morphogenesis checkpoint","type":"exact"},{"name":"stimulus sensing involved in septin checkpoint","type":"related"}],"termid":"GO:1903821"}


id: PBO:0068365
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein 148","termid":"PBO:0068365"}


id: GO:0052179
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete metabolism by symbiont of host cell wall pectin (obsolete GO:0052179)","synonyms":[{"name":"metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction","type":"narrow"}],"termid":"GO:0052179"}


id: PR:O43066
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ppk30 gene.","definition_xrefs":["UniProtKB:O43066","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine-protein kinase ppk30 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC6B1.02","synonyms":[{"name":"Spom972h-ppk30","type":"exact"}],"termid":"PR:O43066"}


id: SO:0001165
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A promoter motif with consensus sequence CARCCCT.","definition_xrefs":["PMID:16827941"],"direct_ancestors":[{"relation_name":"is_a","term_name":"promoter_element","termid":"SO:0001659"},{"relation_name":"part_of","term_name":"RNApol_II_promoter","termid":"SO:0000170"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DMv1_motif","synonyms":[{"name":"DMv1","type":"related"},{"name":"DMv1 motif","type":"exact"},{"name":"directional promoter motif v1","type":"related"}],"termid":"SO:0001165"}


id: GO:0004463
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + leukotriene A(4) = leukotriene B(4).","definition_xrefs":["RHEA:22324","EC:3.3.2.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ether hydrolase activity","termid":"GO:0016803"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"leukotriene-A4 hydrolase activity","secondary_identifiers":["Reactome:R-HSA-266072","MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN","KEGG_REACTION:R03057"],"synonyms":[{"name":"(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity","type":"related"},{"name":"LTA-4 hydrolase activity","type":"related"},{"name":"LTA4 hydrolase activity","type":"related"},{"name":"LTA4H","type":"related"},{"name":"leukotriene A(4) hydrolase activity","type":"related"},{"name":"leukotriene A4 hydrolase activity","type":"related"}],"termid":"GO:0004463"}


id: MOD:01502
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces the O4'-hydrogen atom of a tyrosine residue with the Applied Biosystems iTRAQ4plex-116 reporter+balance group.","definition_xrefs":["OMSSA:175","Unimod:214#Y"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-tyrosine residue","termid":"MOD:00919"},{"relation_name":"is_a","term_name":"iTRAQ4plex-116 reporter+balance reagent acylated residue","termid":"MOD:01499"},{"relation_name":"is_a","term_name":"iTRAQ4plex reporter+balance reagent O-acylated residue","termid":"MOD:01713"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ4plex-116 reporter+balance reagent O4'-acylated tyrosine","synonyms":[{"name":"(4-methylpiperazin-1-yl)acetyl","type":"exact"},{"name":"Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry","type":"related"},{"name":"Representative mass and accurate mass for 116 & 117","type":"related"},{"name":"iTRAQ","type":"related"},{"name":"iTRAQ116Y","type":"exact"},{"name":"iTRAQ4plex","type":"related"}],"termid":"MOD:01502"}


id: MONDO:0010242
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"fetal akinesia deformation sequence","termid":"MONDO:0008824"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fetal akinesia syndrome, X-linked","secondary_identifiers":["UMLS:C1848171","GARD:2293","DOID:0081043","MEDGEN:341166","MESH:C537921","OMIM:300073"],"synonyms":[{"name":"X-linked form of fetal akinesia syndrome","type":"related"},{"name":"X-linked form of foetal akinesia syndrome","type":"related"},{"name":"fetal akinesia syndrome X-linked","type":"related"},{"name":"fetal akinesia syndrome, X-linked","type":"exact"},{"name":"foetal akinesia syndrome X-linked","type":"related"},{"name":"polyhydramnios, hypokinesia, brain malformations, telecanthus, and narrow palpebral fissures","type":"related"}],"termid":"MONDO:0010242","xrefs":{"Monarch":{"xref_id":"0010242"}}}


id: PBO:0028364
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-multiseptate_cell","termid":"PBO:0028364"}


id: GO:0047286
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.","definition_xrefs":["EC:2.4.2.36"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pentosyltransferase activity","termid":"GO:0016763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016757","GO:0003674","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"NAD+-diphthamide ADP-ribosyltransferase activity","secondary_identifiers":["RHEA:11820","Reactome:R-HSA-5336421","MetaCyc:RXN-11372"],"synonyms":[{"name":"ADP-ribosyltransferase activity","type":"broad"},{"name":"NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity","type":"related"},{"name":"NAD-diphthamide ADP-ribosyltransferase activity","type":"exact"},{"name":"mono(ADP-ribosyl)transferase activity","type":"broad"}],"termid":"GO:0047286"}


id: GO:0005905
data:
  {"annotated_genes":["SJAG_04517","SJAG_04609","SJAG_04565","SJAG_02805","SJAG_00104","SJAG_01167","SJAG_02282","SJAG_01748","SJAG_00800"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[58835,65699,74059,113168,113380],"is_not":false,"summary":null,"term":"GO:0005905"},{"annotations":[108708,74728,58349,78470],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0030122"}]},"cv_name":"cellular_component","definition":"A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.","definition_xrefs":["ISBN:0198506732","NIF_Subcellular:sao1969557946","PMID:17284835","GOC:mah","PMID:10559856"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane","termid":"GO:0016020"},{"relation_name":"part_of","term_name":"endomembrane system","termid":"GO:0012505"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00104":null,"SJAG_00800":null,"SJAG_01167":null,"SJAG_01748":null,"SJAG_02282":null,"SJAG_02805":null,"SJAG_04517":null,"SJAG_04565":null,"SJAG_04609":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"clathrin-coated pit","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000043":null,"GO_REF:0000107":null},"synonyms":[{"name":"coated pit","type":"exact"}],"termid":"GO:0005905","terms_by_termid":{"GO:0005905":null,"GO:0030122":null}}


id: MONDO:0011220
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"young-onset Parkinson disease","termid":"MONDO:0017279"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"parkinson disease 3, autosomal dominant","secondary_identifiers":["DOID:0111250","MESH:C566552","OMIM:602404","GARD:8578","MEDGEN:355499","UMLS:C1865581"],"synonyms":[{"name":"PARK3","type":"exact"},{"name":"Parkinson disease 3","type":"exact"},{"name":"Parkinson disease 3, autosomal dominant","type":"related"},{"name":"Parkinson disease 3, autosomal dominant Lewy body","type":"related"},{"name":"Parkinson disease type 3","type":"related"},{"name":"autosomal dominant Parkinson disease","type":"related"}],"termid":"MONDO:0011220","xrefs":{"Monarch":{"xref_id":"0011220"}}}


id: GO:0030677
data:
  {"annotated_genes":["SJAG_02547","SJAG_01623","SJAG_04916","SJAG_00955","SJAG_06613","SJAG_03796","SJAG_02553","SJAG_01369","SJAG_03234","SJAG_00306","SJAG_04582"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[115687,115775,91447,60656,71585,63798,118975,72018,99848,72052,104920],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005655"}]},"cv_name":"cellular_component","definition":"A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.","definition_xrefs":["PMID:12045094","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endoribonuclease complex","termid":"GO:1902555"},{"relation_name":"is_a","term_name":"ribonucleoprotein complex","termid":"GO:1990904"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00306":null,"SJAG_00955":null,"SJAG_01369":null,"SJAG_01623":null,"SJAG_02547":null,"SJAG_02553":null,"SJAG_03234":null,"SJAG_03796":null,"SJAG_04582":null,"SJAG_04916":null,"SJAG_06613":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"ribonuclease P complex","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"RNase P complex","type":"exact"}],"termid":"GO:0030677","terms_by_termid":{"GO:0005655":null}}


id: PBO:0041263
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"complement C1q binding protein","termid":"PBO:0041263"}


id: MONDO:0850059
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hereditary persistence of fetal hemoglobin-intellectual disability syndrome","secondary_identifiers":["Orphanet:619233","GARD:22458"],"termid":"MONDO:0850059","xrefs":{"Monarch":{"xref_id":"0850059"}}}


id: PBO:0080504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WAPL cohesin release factor","termid":"PBO:0080504"}


id: PBO:0081890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 840, pseudogene","termid":"PBO:0081890"}


id: PBO:0002149
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"focus formation at heterochromatic regions, Swi6_dependent","termid":"PBO:0002149"}


id: FYPO:0004488
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of one or more lysine residues in specific proteins, or at specific protein sites, does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein modification during vegetative growth","termid":"FYPO:0000544"},{"relation_name":"is_a","term_name":"abnormal protein acetylation during vegetative growth","termid":"FYPO:0002392"},{"relation_name":"is_a","term_name":"abolished biological process","termid":"FYPO:0005448"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0002274","FYPO:0005447","FYPO:0000002","FYPO:0002494"],"is_obsolete":false,"name":"abolished protein lysine methylation during vegetative growth","synonyms":[{"name":"abolished peptidyl-lysine methylation during vegetative growth","type":"exact"},{"name":"abolished protein acetylation during mitotic cell cycle","type":"related"},{"name":"protein lysine methylation abolished during vegetative growth","type":"exact"},{"name":"protein lysine methylation absent during vegetative growth","type":"exact"}],"termid":"FYPO:0004488"}


id: MONDO:0010349
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any primary ovarian failure in which the cause of the disease is a mutation in the BMP15 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"46 XX gonadal dysgenesis","termid":"MONDO:0009299"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"ovarian dysgenesis 2","secondary_identifiers":["MEDGEN:336903","MESH:C564499","OMIM:300510","DOID:0080494","UMLS:C1845294","DOID:0080861","GARD:18040"],"synonyms":[{"name":"BMP15 primary ovarian failure","type":"exact"},{"name":"ODG2","type":"related"},{"name":"ovarian dysgenesis 2","type":"exact"},{"name":"ovarian dysgenesis type 2","type":"exact"},{"name":"ovarian dysgenesis, hypergonadotropic, X-linked","type":"related"},{"name":"ovarian failure, hypergonadotropic, due to ovarian dysgenesis","type":"related"},{"name":"premature ovarian failure 4","type":"related"},{"name":"primary ovarian failure caused by mutation in BMP15","type":"exact"}],"termid":"MONDO:0010349","xrefs":{"Monarch":{"xref_id":"0010349"}}}


id: MONDO:0021171
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Classic form of Timothy syndrome, includes all features of generic.","direct_ancestors":[{"relation_name":"is_a","term_name":"Timothy syndrome","termid":"MONDO:0010979"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0005267","MONDO:0000426"],"is_obsolete":false,"name":"Timothy syndrome, classic type","secondary_identifiers":["ICD9:759.89","SCTID:699256006"],"synonyms":[{"name":"Timothy syndrome type 1 (disorder)","type":"exact"}],"termid":"MONDO:0021171","xrefs":{"Monarch":{"xref_id":"0021171"}}}


id: MONDO:0043862
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A pathologic process in the larynx that affects the production of speech. Causes include vocal cord paresis, vocal cord nodule, vocal cord polyp, and laryngitis.","definition_xrefs":["NCIT:C3441"],"direct_ancestors":[{"relation_name":"is_a","term_name":"laryngeal disorder","termid":"MONDO:0004382"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"voice disorders","secondary_identifiers":["SCTID:71941009","MEDGEN:12120","MESH:D014832","UMLS:C0042940","EFO:0009692"],"synonyms":[{"name":"neurologic dysphonia","type":"related"},{"name":"neurologic voice disorder","type":"exact"},{"name":"voice disorder","type":"exact"}],"termid":"MONDO:0043862","xrefs":{"Monarch":{"xref_id":"0043862"}}}


id: PBO:0041516
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 15 open reading frame 48","termid":"PBO:0041516"}


id: GO:0000727
data:
  {"annotated_genes":["SJAG_00857","SJAG_04210","SJAG_01044","SJAG_01354","SJAG_01762","SJAG_04995","SJAG_00884","SJAG_00696","SJAG_05180","SJAG_03160","SJAG_01624","SJAG_02348","SJAG_00327"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70345,71423,72429,73653,73839,74800,74997,77768,78550,80351,80686,99640,112417],"is_not":false,"summary":null,"term":"GO:0000727"}]},"cv_name":"biological_process","definition":"The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.","definition_xrefs":["PMID:10357855","GOC:elh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"double-strand break repair via homologous recombination","termid":"GO:0000724"}],"gene_count":13,"genes_by_uniquename":{"SJAG_00327":null,"SJAG_00696":null,"SJAG_00857":null,"SJAG_00884":null,"SJAG_01044":null,"SJAG_01354":null,"SJAG_01624":null,"SJAG_01762":null,"SJAG_02348":null,"SJAG_03160":null,"SJAG_04210":null,"SJAG_04995":null,"SJAG_05180":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"is_a","termid":"GO:0006310"},{"rel_name":"is_a","termid":"GO:0006281"}],"interesting_parent_ids":["GO:0006281","GO:0006259","GO:0006310","GO:0008150"],"is_obsolete":false,"name":"double-strand break repair via break-induced replication","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0000727","terms_by_termid":{"GO:0000727":null}}


id: GO:0051311
data:
  {"annotated_genes":["SJAG_05019","SJAG_01805","SJAG_07002","SJAG_00918","SJAG_03683","SJAG_03989","SJAG_01775","SJAG_03698","SJAG_01837","SJAG_00418","SJAG_00678","SJAG_03926","SJAG_02731","SJAG_03437","SJAG_05220","SJAG_03217","SJAG_04259","SJAG_00794","SJAG_01371","SJAG_02346","SJAG_05266","SJAG_05319","SJAG_01224","SJAG_04076","SJAG_01278","SJAG_05295","SJAG_03220","SJAG_01211","SJAG_04508","SJAG_02814","SJAG_03327"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[94195,88225],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051456"},{"annotations":[117444,108192,101696,94159,90647,88168,98978,114165,115920],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0031619"},{"annotations":[117066],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1904967"},{"annotations":[95923,110698,90111,94176,109522,107875,110273,109266,95678,100889,91346,89506,116307,98986,108196,113613,110741,117301,114481,98265,105848,102798,101700],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0051455"}]},"cv_name":"biological_process","definition":"A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.","definition_xrefs":["GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"metaphase chromosome alignment","termid":"GO:0051310"},{"relation_name":"is_a","term_name":"meiotic cell cycle process","termid":"GO:1903046"},{"relation_name":"part_of","term_name":"meiotic chromosome segregation","termid":"GO:0045132"}],"gene_count":31,"genes_by_uniquename":{"SJAG_00418":null,"SJAG_00678":null,"SJAG_00794":null,"SJAG_00918":null,"SJAG_01211":null,"SJAG_01224":null,"SJAG_01278":null,"SJAG_01371":null,"SJAG_01775":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_02346":null,"SJAG_02731":null,"SJAG_02814":null,"SJAG_03217":null,"SJAG_03220":null,"SJAG_03327":null,"SJAG_03437":null,"SJAG_03683":null,"SJAG_03698":null,"SJAG_03926":null,"SJAG_03989":null,"SJAG_04076":null,"SJAG_04259":null,"SJAG_04508":null,"SJAG_05019":null,"SJAG_05220":null,"SJAG_05266":null,"SJAG_05295":null,"SJAG_05319":null,"SJAG_07002":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0140013"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0007049","GO:0140013","GO:0008150"],"is_obsolete":false,"name":"meiotic metaphase chromosome alignment","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"metaphase plate congression during meiosis","type":"exact"}],"termid":"GO:0051311","terms_by_termid":{"GO:0031619":null,"GO:0051455":null,"GO:0051456":null,"GO:1904967":null}}


id: PBO:0064788
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase, Mg2+/Mn2+ dependent 1H","termid":"PBO:0064788"}


id: MONDO:0007869
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Kyrle disease is rare condition that affects the skin. People with this condition generally develop large papules with central keratin (a protein found in the skin, hair and nails) plugs throughout their body. These lesions are typically not painful but may cause severe itching. Although it can affect both men and women throughout life, the average age of onset is 30 years. The cause of the disease is currently unknown; however, it is often associated with certain conditions such as diabetes mellitus, kidney disease, liver abnormalities, and congestive heart failure. In some families, the condition appears to be inherited but an underlying genetic cause has not been identified. Treatment aims to address the associated signs and symptoms and any additional disease that may be present. Lesions often heal spontaneously but new ones continue to develop.","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kyrle disease","secondary_identifiers":["SCTID:34042008","OMIM:149500","UMLS:C0263382","MEDGEN:75516","MESH:C538130"],"synonyms":[{"name":"Kyrle disease","type":"exact"},{"name":"Kyrle's disease","type":"related"},{"name":"hyperkeratosis follicularis et parafollicularis in cutem penetrans","type":"related"}],"termid":"MONDO:0007869","xrefs":{"Monarch":{"xref_id":"0007869"}}}


id: PBO:0057211
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 378a","termid":"PBO:0057211"}


id: PBO:0025495
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoribosylpyrophosphate synthetase superactivity","termid":"PBO:0025495"}


id: PBO:0046445
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"erythropoietin","termid":"PBO:0046445"}


id: GO:0099034
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.","definition_xrefs":["GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete anchored component of postsynaptic endosome membrane (obsolete GO:0099034)","termid":"GO:0099034"}


id: GO:0008121
data:
  {"annotated_genes":["SJAG_01490","SJAG_00755","SJAG_00601","SJAG_02646","SJAG_07006","SJAG_03490","SJAG_MIT03"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[64203,104440,108337,113786,118069,118551,119443],"is_not":false,"summary":null,"term":"GO:0008121"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+.","definition_xrefs":["RHEA:11484"],"direct_ancestors":[{"relation_name":"is_a","term_name":"electron transfer activity","termid":"GO:0009055"},{"relation_name":"is_a","term_name":"proton transmembrane transporter activity","termid":"GO:0015078"},{"relation_name":"is_a","term_name":"oxidoreduction-driven active transmembrane transporter activity","termid":"GO:0015453"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on diphenols and related substances as donors","termid":"GO:0016679"},{"relation_name":"is_a","term_name":"active monoatomic ion transmembrane transporter activity","termid":"GO:0022853"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00601":null,"SJAG_00755":null,"SJAG_01490":null,"SJAG_02646":null,"SJAG_03490":null,"SJAG_07006":null,"SJAG_MIT03":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0003824","GO:0016491","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"ubiquinol-cytochrome-c reductase activity","references_by_uniquename":{"GO_REF:0000003":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0045154","MetaCyc:RXN-15816","Reactome:R-HSA-164651","GO:0045153","EC:7.1.1.8"],"synonyms":[{"name":"complex III (mitochondrial electron transport) activity","type":"narrow"},{"name":"cytochrome","type":"broad"},{"name":"cytochrome a","type":"narrow"},{"name":"cytochrome a3/copper complex","type":"narrow"},{"name":"cytochrome b562","type":"narrow"},{"name":"cytochrome b566","type":"narrow"},{"name":"cytochrome c1","type":"narrow"},{"name":"electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity","type":"related"},{"name":"electron transporter, transferring electrons within cytochrome c oxidase complex activity","type":"related"},{"name":"mitochondrial electron transport complex III","type":"related"},{"name":"soluble cytochrome b562","type":"narrow"},{"name":"ubiquinol-cytochrome c oxidoreductase activity","type":"related"},{"name":"ubiquinol-cytochrome c-2 oxidoreductase activity","type":"related"},{"name":"ubiquinol-cytochrome c1 oxidoreductase activity","type":"related"},{"name":"ubiquinol-cytochrome c2 reductase activity","type":"related"},{"name":"ubiquinol:ferricytochrome-c oxidoreductase activity","type":"related"},{"name":"ubiquinone--cytochrome-c oxidoreductase activity","type":"related"},{"name":"ubiquinone-cytochrome c oxidoreductase activity","type":"related"},{"name":"ubiquinone-cytochrome c reductase activity","type":"related"}],"termid":"GO:0008121","terms_by_termid":{"GO:0008121":null}}


id: GO:0048918
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.","definition_xrefs":["GOC:jid","GOC:dgh","GOC:cls","GOC:dph","ISBN:0125296509","GO_REF:0000021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lateral line nerve development","termid":"GO:0048892"},{"relation_name":"part_of","term_name":"posterior lateral line system development","termid":"GO:0048915"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"posterior lateral line nerve development","secondary_identifiers":["GO:0021733"],"synonyms":[{"name":"PLLN development","type":"exact"},{"name":"caudal lateral line nerve development","type":"exact"}],"termid":"GO:0048918"}


id: MONDO:0001051
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute form of otitis externa.","definition_xrefs":["MONDO:design_pattern"],"direct_ancestors":[{"relation_name":"is_a","term_name":"otitis externa","termid":"MONDO:0004795"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acute otitis externa","secondary_identifiers":["MEDGEN:508459","DOID:10518","SCTID:30250000","UMLS:C0149948","ICD9:380.12"],"synonyms":[{"name":"acute bacterial inflammation of external ear","type":"exact"},{"name":"acute otitis externa","type":"exact"},{"name":"acute otitis externa, diffuse","type":"exact"},{"name":"acute swimmer's ear","type":"exact"},{"name":"acute swimmers' ear","type":"exact"},{"name":"beach ear","type":"exact"},{"name":"otitis externa, acute","type":"exact"},{"name":"tank ear","type":"exact"}],"termid":"MONDO:0001051","xrefs":{"Monarch":{"xref_id":"0001051"}}}


id: PBO:0066929
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 231","termid":"PBO:0066929"}


id: MONDO:0022007
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition resulting from the excessive retention of water with sodium depletion.","definition_xrefs":["MESH:D014869"],"direct_ancestors":[{"relation_name":"is_a","term_name":"poisoning","termid":"MONDO:0029000"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"water intoxication","secondary_identifiers":["SCTID:71785001","MEDGEN:53061","UMLS:C0043049"],"synonyms":[{"name":"WATER INTOX","type":"related"},{"name":"Water Intoxication","type":"related"},{"name":"Water intoxication","type":"related"},{"name":"Water intoxication syndrome","type":"related"},{"name":"water intoxication syndrome","type":"exact"}],"termid":"MONDO:0022007","xrefs":{"Monarch":{"xref_id":"0022007"}}}


id: PBO:0065244
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline rich 15 like","termid":"PBO:0065244"}


id: PBO:0060099
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND5 pseudogene 46","termid":"PBO:0060099"}


id: GO:0001619
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity.","definition_xrefs":["GOC:dph"],"gene_count":0,"genotype_count":0,"name":"obsolete lysosphingolipid and lysophosphatidic acid receptor activity (obsolete GO:0001619)","synonyms":[{"name":"lysosphingolipid and lysophosphatidic acid receptor activity","type":"exact"}],"termid":"GO:0001619"}


id: GO:1902966
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.","definition_xrefs":["GOC:sjp","GO_REF:0000058","GOC:TermGenie","PMID:22621900"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein localization to early endosome","termid":"GO:1902965"},{"relation_name":"is_a","term_name":"positive regulation of protein localization to endosome","termid":"GO:1905668"},{"relation_name":"positively_regulates","term_name":"protein localization to early endosome","termid":"GO:1902946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of protein localization to early endosome","synonyms":[{"name":"activation of protein localisation in early endosome","type":"narrow"},{"name":"activation of protein localisation to early endosome","type":"narrow"},{"name":"activation of protein localization in early endosome","type":"narrow"},{"name":"activation of protein localization to early endosome","type":"narrow"},{"name":"positive regulation of protein localisation in early endosome","type":"exact"},{"name":"positive regulation of protein localisation to early endosome","type":"exact"},{"name":"positive regulation of protein localization in early endosome","type":"exact"},{"name":"up regulation of protein localisation in early endosome","type":"exact"},{"name":"up regulation of protein localisation to early endosome","type":"exact"},{"name":"up regulation of protein localization in early endosome","type":"exact"},{"name":"up regulation of protein localization to early endosome","type":"exact"},{"name":"up-regulation of protein localisation in early endosome","type":"exact"},{"name":"up-regulation of protein localisation to early endosome","type":"exact"},{"name":"up-regulation of protein localization in early endosome","type":"exact"},{"name":"up-regulation of protein localization to early endosome","type":"exact"},{"name":"upregulation of protein localisation in early endosome","type":"exact"},{"name":"upregulation of protein localisation to early endosome","type":"exact"},{"name":"upregulation of protein localization in early endosome","type":"exact"},{"name":"upregulation of protein localization to early endosome","type":"exact"}],"termid":"GO:1902966"}


id: MONDO:0015972
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A form of anemia (disease) that is both rare and inborn.","definition_xrefs":["MONDO:patterns/rare_genetic"],"gene_count":0,"genotype_count":0,"name":"obsolete rare constitutional anemia (obsolete MONDO:0015972)","secondary_identifiers":["Orphanet:183651"],"synonyms":[{"name":"rare constitutional anemia (disease)","type":"exact"},{"name":"rare genetic anemia (disease)","type":"exact"},{"name":"rare inborn anemia (disease)","type":"exact"}],"termid":"MONDO:0015972","xrefs":{"Monarch":{"xref_id":"0015972"}}}


id: FYPO:0008349
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of 5'-nucleotidase activity is abnormal.","direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal catalytic activity","termid":"FYPO:0000661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000707","FYPO:0001985","FYPO:0000652","FYPO:0000661"],"is_obsolete":false,"name":"abnormal 5'-nucleotidase activity","termid":"FYPO:0008349"}


id: SO:0001672
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A DNA sequence to which bacterial RNA polymerase sigma 54 binds, to begin transcription.","direct_ancestors":[{"relation_name":"is_a","term_name":"bacterial_RNApol_promoter","termid":"SO:0000613"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bacterial_RNApol_promoter_sigma54_element","synonyms":[{"name":"<new synonym>","type":"related"},{"name":"bacterial RNA polymerase promoter sigma54","type":"exact"}],"termid":"SO:0001672"}


id: PBO:0089442
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane urea transmembrane transporter","termid":"PBO:0089442"}


id: GO:2000308
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of tumor necrosis factor superfamily cytokine production","termid":"GO:1903556"},{"relation_name":"is_a","term_name":"regulation of tumor necrosis factor (ligand) superfamily member 11 production","termid":"GO:2000307"},{"relation_name":"negatively_regulates","term_name":"tumor necrosis factor (ligand) superfamily member 11 production","termid":"GO:0072535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of tumor necrosis factor (ligand) superfamily member 11 production","synonyms":[{"name":"negative regulation of RANKL production","type":"exact"},{"name":"negative regulation of TNFSF11 production","type":"exact"}],"termid":"GO:2000308"}


id: PBO:0114502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Poly(A) RNA binding protein involved in nuclear mRNA export; component of the nuclear pore and nuclear RNA export factor; ubiquitin-associated (UBA) domain interacts with Mip6p; ortholog of human TAP","termid":"PBO:0114502"}


id: PBO:0003481
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTPase binding protein Rid1 (predicted)","termid":"PBO:0003481"}


id: GO:1903486
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any establishment of actomyosin contractile ring localization that is involved in mitotic cell cycle.","definition_xrefs":["GOC:mtg_cell_cycle","GOC:TermGenie","GO_REF:0000060"],"gene_count":0,"genotype_count":0,"name":"obsolete establishment of mitotic actomyosin contractile ring localization (obsolete GO:1903486)","termid":"GO:1903486"}


id: GO:0051246
data:
  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id: PBO:0109297
data:
  {"annotation_feature_type":"gene","cv_name":"misc","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"codon-optimization decreases protein concentration","termid":"PBO:0109297"}


id: PBO:0043991
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chondroitin sulfate N-acetylgalactosaminyltransferase 1","termid":"PBO:0043991"}


id: PBO:0040115
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and SOCS box containing 2","termid":"PBO:0040115"}


id: MOD:01986
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-serine.","definition_xrefs":["RESID:AA0623","PubMed:21526839"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-carbon thioether crosslinked residues","termid":"MOD:01992"},{"relation_name":"is_a","term_name":"crosslinked L-serine residue","termid":"MOD:02055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00905"}],"interesting_parent_ids":["MOD:00905"],"is_obsolete":false,"name":"2-(L-cystein-S-yl)-L-serine","synonyms":[{"name":"(2R)-2-amino-2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-3-hydroxypropanoic acid","type":"exact"},{"name":"(2R,5R)-2,5-diamino-5-carboxy-6-hydroxy-4-thiahexanoic acid","type":"exact"}],"termid":"MOD:01986"}


id: PBO:0058951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"muskelin 1","termid":"PBO:0058951"}


id: FYPO:0002986
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased during a cellular response to ionizing radiation. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased chromatin binding","termid":"FYPO:0002980"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000702"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000702","FYPO:0000707","FYPO:0001985","FYPO:0000652"],"is_obsolete":false,"name":"increased chromatin binding during cellular response to ionizing radiation","synonyms":[{"name":"increased chromatin binding during cellular response to IR","type":"exact"}],"termid":"FYPO:0002986"}


id: PBO:0053750
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 987","termid":"PBO:0053750"}


id: GO:0000145
data:
  {"annotated_genes":["SJAG_03357","SJAG_02166","SJAG_02753","SJAG_04044","SJAG_03864","SJAG_04960","SJAG_01925","SJAG_02320","SJAG_03938"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[57453,63267,67610,71148,73014,76391,76803,77758,91107],"is_not":false,"summary":null,"term":"GO:0000145"}]},"cv_name":"cellular_component","definition":"A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.","definition_xrefs":["PMID:27243008","GOC:cilia","PMID:15292201","PMID:9700152"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle tethering complex","termid":"GO:0099023"},{"relation_name":"part_of","term_name":"cell cortex","termid":"GO:0005938"}],"gene_count":9,"genes_by_uniquename":{"SJAG_01925":null,"SJAG_02166":null,"SJAG_02320":null,"SJAG_02753":null,"SJAG_03357":null,"SJAG_03864":null,"SJAG_03938":null,"SJAG_04044":null,"SJAG_04960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005938"}],"interesting_parent_ids":["GO:0005938","GO:0005575","GO:0005737","GO:0032991"],"is_obsolete":false,"name":"exocyst","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Wikipedia:Exocyst"],"synonyms":[{"name":"Sec6/8 complex","type":"exact"},{"name":"exocyst complex","type":"exact"}],"termid":"GO:0000145","terms_by_termid":{"GO:0000145":null}}


id: PBO:0031512
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_mating_efficiency","termid":"PBO:0031512"}


id: PBO:0065658
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase receptor type H","termid":"PBO:0065658"}


id: GO:1904023
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","GOC:dph","PMID:20935145"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of glucose metabolic process","termid":"GO:0010906"},{"relation_name":"is_a","term_name":"regulation of fermentation","termid":"GO:0043465"},{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"regulates","term_name":"glucose catabolic process to lactate via pyruvate","termid":"GO:0019661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006091"},{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006091","GO:0005975"],"is_obsolete":false,"name":"regulation of glucose catabolic process to lactate via pyruvate","synonyms":[{"name":"regulation of glucose fermentation to lactate via pyruvate","type":"exact"},{"name":"regulation of homofermentation","type":"exact"},{"name":"regulation of homofermentative lactate fermentation","type":"exact"},{"name":"regulation of homofermentative pathway","type":"exact"},{"name":"regulation of homolactate fermentation","type":"exact"},{"name":"regulation of homolactic fermentation","type":"exact"}],"termid":"GO:1904023"}


id: PBO:0031615
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_transposition","termid":"PBO:0031615"}


id: GO:0102198
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+.","definition_xrefs":["GOC:pz","RHEA:21172"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"L-idonate 5-dehydrogenase (NAD+) activity","secondary_identifiers":["MetaCyc:RXN-12107","EC:1.1.1.366"],"synonyms":[{"name":"L-idonate 5-dehydrogenase activity (NAD-dependent)","type":"exact"}],"termid":"GO:0102198"}


id: PBO:0068851
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 89, pseudogene","termid":"PBO:0068851"}


id: GO:0050538
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.","definition_xrefs":["MetaCyc:3.5.1.87-RXN","EC:3.5.1.87"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","termid":"GO:0016811"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824","GO:0016810"],"is_obsolete":false,"name":"N-carbamoyl-L-amino-acid hydrolase activity","secondary_identifiers":["RHEA:17581"],"synonyms":[{"name":"L-carbamoylase activity","type":"related"},{"name":"N-carbamoyl-L-amino acid amidohydrolase activity","type":"related"}],"termid":"GO:0050538"}


id: PBO:0051744
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"integrator complex subunit 10","termid":"PBO:0051744"}


id: PBO:0026667
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-septated_mononucleate_vegetative_cell","termid":"PBO:0026667"}


id: MONDO:0100523
data:
  {"annotated_genes":["SJAG_04566","SJAG_01530"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86867,86866],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008438"}]},"cv_name":"mondo","definition":"Heterozygous variants in SPAST have been reported in relation to pure spastic paraplegias (infantile, ascending), complicated or complex spastic paraplegia (with dementia, cerebellar ataxia, epilepsy, and/or peripheral neuropathy) and cerebral palsy. Age of symptom onset ranges from neonatal to advanced age with varying symptom severity,","direct_ancestors":[{"relation_name":"is_a","term_name":"central nervous system disorder","termid":"MONDO:0002602"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01530":null,"SJAG_04566":null},"genotype_count":0,"is_obsolete":false,"name":"SPAST-related motor disorder","references_by_uniquename":{"PB_REF:0000006":null},"termid":"MONDO:0100523","terms_by_termid":{"MONDO:0008438":null},"xrefs":{"Monarch":{"xref_id":"0100523"}}}


id: MONDO:0009677
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Autosomal recessive limb-girdle muscular dystrophy type 2C (LGMD2C) is a subtype of autosomal recessive limb-girdle muscular dystrophy characterized by a childhood onset of progressive shoulder and pelvic girdle muscle weakness and atrophy frequently associated with calf hypertrophy, diaphragmatic weakness, and/or variable cardiac abnormalities. Mild to moderate elevated serum creatine kinase levels and positive Gowers sign are reported.","definition_xrefs":["Orphanet:353"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive limb-girdle muscular dystrophy","termid":"MONDO:0015152"},{"relation_name":"is_a","term_name":"qualitative or quantitative defects of gamma-sarcoglycan","termid":"MONDO:0016143"},{"relation_name":"is_a","term_name":"familial dilated cardiomyopathy","termid":"MONDO:0016333"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005267","MONDO:0005336"],"is_obsolete":false,"name":"autosomal recessive limb-girdle muscular dystrophy type 2C","secondary_identifiers":["MEDGEN:98045","UMLS:C0410173","DOID:0110277","GARD:2429","MESH:C535900","OMIM:253700"],"synonyms":[{"name":"Adhalin deficiency, secondary","type":"related"},{"name":"DMDA1","type":"exact"},{"name":"Dmda","type":"related"},{"name":"Duchenne-like muscular dystrophy, autosomal recessive, type 1","type":"related"},{"name":"LGMD2C","type":"exact"},{"name":"Maghrebian myopathy","type":"exact"},{"name":"SCARMD","type":"exact"},{"name":"SGCG autosomal recessive limb-girdle muscular dystrophy","type":"exact"},{"name":"autosomal recessive Duchenne-like muscular dystrophy type 1","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy caused by mutation in SGCG","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy type 2C","type":"exact"},{"name":"deficiency of sarcoglycan gamma","type":"exact"},{"name":"gamma-sarcoglycanopathy","type":"exact"},{"name":"limb-girdle muscular dystrophy due to gamma-sarcoglycan deficiency","type":"exact"},{"name":"limb-girdle muscular dystrophy with gamma-sarcoglycan deficiency","type":"related"},{"name":"limb-girdle muscular dystrophy, type 2C","type":"related"},{"name":"muscular dystrophy, Duchenne-like","type":"related"},{"name":"muscular dystrophy, limb-girdle, autosomal recessive 5","type":"exact"},{"name":"muscular dystrophy, limb-girdle, type 2C","type":"exact"},{"name":"sarcoglycan, gamma, deficiency of","type":"related"},{"name":"severe childhood autosomal recessive muscular dystrophy North African type","type":"exact"},{"name":"severe childhood autosomal recessive muscular dystrophy, North African type","type":"related"}],"termid":"MONDO:0009677","xrefs":{"Monarch":{"xref_id":"0009677"}}}


id: PBO:0058069
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4288","termid":"PBO:0058069"}


id: FYPO:0009026
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing methionine as the nitrogen source.","definition_xrefs":["PomBase:mlr"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased vegetative cell population growth","termid":"FYPO:0004557"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0002058","FYPO:0001985","FYPO:0000003","FYPO:0005447","FYPO:0002057"],"is_obsolete":false,"name":"increased cell population growth on methionine nitrogen source","synonyms":[{"name":"increased growth on methionine nitrogen source","type":"broad"},{"name":"increased vegetative cell growth on methionine nitrogen source","type":"exact"}],"termid":"FYPO:0009026"}


id: GO:0097432
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.","definition_xrefs":["GOC:jc","PMID:19342486","CL:1001571"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyramidal neuron differentiation","termid":"GO:0021859"},{"relation_name":"is_a","term_name":"cerebral cortex neuron differentiation","termid":"GO:0021895"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hippocampal pyramidal neuron differentiation","termid":"GO:0097432"}


id: PBO:0063587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peroxisomal biogenesis factor 2","termid":"PBO:0063587"}


id: MONDO:0012826
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"scoliosis, isolated, susceptibility to, 4","secondary_identifiers":["UMLS:C2677108","MEDGEN:393659","OMIM:612238"],"synonyms":[{"name":"IS4","type":"exact"},{"name":"scoliosis, idiopathic, susceptibility to, 4","type":"exact"},{"name":"scoliosis, isolated, susceptibility to, 4","type":"exact"}],"termid":"MONDO:0012826","xrefs":{"Monarch":{"xref_id":"0012826"}}}


id: PBO:0043668
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coenzyme Q10B","termid":"PBO:0043668"}


id: MONDO:0007575
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete erythrokeratodermia variabilis (obsolete MONDO:0007575)","termid":"MONDO:0007575","xrefs":{"Monarch":{"xref_id":"0007575"}}}


id: PBO:0059543
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrially encoded tRNA-Lys (AAA/G)","termid":"PBO:0059543"}


id: GO:0015955
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.","definition_xrefs":["ISBN:0306444747","ISBN:0471394831","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pyrimidine deoxyribonucleotide metabolic process","termid":"GO:0009219"},{"relation_name":"is_a","term_name":"pyrimidine nucleotide interconversion","termid":"GO:0015953"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"pyrimidine deoxyribonucleotide interconversion","termid":"GO:0015955"}


id: GO:0043799
data:
  {"annotated_genes":["SJAG_02496"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[115134],"is_not":false,"summary":null,"term":"GO:0043799"}]},"cv_name":"molecular_function","definition":"Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide.","definition_xrefs":["EC:1.4.3.19"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aliphatic amine oxidase activity","termid":"GO:0052595"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02496":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"glycine oxidase activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"glycine:oxygen oxidoreductase (deaminating)","type":"exact"}],"termid":"GO:0043799","terms_by_termid":{"GO:0043799":null}}


id: MONDO:0014873
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare developmental skin condition consisting of abnormal pilosebaceous follicle development. It is characterized by linear or band-like distributions of groups of comedones, usually on the face, neck, upper arm, chest, and abdomen, that appear at birth or in childhood.","definition_xrefs":["NCIT:C3946"],"direct_ancestors":[{"relation_name":"is_a","term_name":"melanocytic nevus","termid":"MONDO:0005073"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"nevus comedonicus syndrome","secondary_identifiers":["Orphanet:64754","UMLS:C0265987","GARD:13073","MEDGEN:75592","OMIM:617025","SCTID:35962006"],"synonyms":[{"name":"NC","type":"related"},{"name":"NEVUS comedonicus","type":"related"},{"name":"Nevus comedonicus","type":"exact"},{"name":"acne Nevus","type":"exact"},{"name":"acneiform Nevus","type":"exact"},{"name":"comedo Nevus","type":"exact"},{"name":"nevus comedonicus, somatic","type":"exact"},{"name":"pilosebaceous nevoid disorder","type":"exact"}],"termid":"MONDO:0014873","xrefs":{"Monarch":{"xref_id":"0014873"}}}


id: GO:0141053
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the transfer of ubiquitin to a histone H2A substrate.","definition_xrefs":["PMID:25303536"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone ubiquitin ligase activity","termid":"GO:0140852"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0004842"},{"rel_name":"is_a","termid":"GO:0019787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140096"}],"interesting_parent_ids":["GO:0016746","GO:0004842","GO:0003674","GO:0019787","GO:0003824","GO:0140096","GO:0016740"],"is_obsolete":false,"name":"histone H2A ubiquitin ligase activity","termid":"GO:0141053"}


id: MONDO:0017589
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Follicular cholangitis and pancreatitis is a rare pancreatobiliary disease characterized by marked duct-centered lymphoid follicular inflammation that develops in both biliary and pancreatic ductal systems, mainly affecting the hilar bile ducts and the pancreatic head. Patients present with jaundice, abdominal pain, liver dysfunction, pruritus and/or weight loss. Histology shows lymphoplasmacytic infiltration with formation of numerous, large lymphpoid follicles around the affected bile and pancreatic ducts.","definition_xrefs":["Orphanet:300552"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pancreas disorder","termid":"MONDO:0002356"},{"relation_name":"is_a","term_name":"biliary tract disorder","termid":"MONDO:0004868"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"follicular cholangitis and pancreatitis","secondary_identifiers":["MEDGEN:1667817","UMLS:C4749906","GARD:21236"],"synonyms":[{"name":"follicular pancreatocholangitis","type":"exact"}],"termid":"MONDO:0017589","xrefs":{"Monarch":{"xref_id":"0017589"}}}


id: PBO:0016578
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X-chromosome Associated Protein","termid":"PBO:0016578"}


id: PBO:0071133
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 135","termid":"PBO:0071133"}


id: GO:1902887
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity.","definition_xrefs":["GO_REF:0000059","GOC:TermGenie","PMID:23995839","GOC:di"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of proteasome-activating ATPase activity (obsolete GO:1902887)","synonyms":[{"name":"activation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"narrow"},{"name":"activation of proteasomal ATPase activity","type":"narrow"},{"name":"activation of proteasome channel gating activity","type":"narrow"},{"name":"activation of proteasome channel opening activity","type":"narrow"},{"name":"activation of proteasome-activating ATPase activity","type":"narrow"},{"name":"positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"positive regulation of proteasomal ATPase activity","type":"exact"},{"name":"positive regulation of proteasome channel gating activity","type":"narrow"},{"name":"positive regulation of proteasome channel opening activity","type":"narrow"},{"name":"up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"up regulation of proteasomal ATPase activity","type":"exact"},{"name":"up regulation of proteasome channel gating activity","type":"narrow"},{"name":"up regulation of proteasome channel opening activity","type":"narrow"},{"name":"up regulation of proteasome-activating ATPase activity","type":"exact"},{"name":"up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"up-regulation of proteasomal ATPase activity","type":"exact"},{"name":"up-regulation of proteasome channel gating activity","type":"narrow"},{"name":"up-regulation of proteasome channel opening activity","type":"narrow"},{"name":"up-regulation of proteasome-activating ATPase activity","type":"exact"},{"name":"upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"upregulation of proteasomal ATPase activity","type":"exact"},{"name":"upregulation of proteasome channel gating activity","type":"narrow"},{"name":"upregulation of proteasome channel opening activity","type":"narrow"},{"name":"upregulation of proteasome-activating ATPase activity","type":"exact"}],"termid":"GO:1902887"}


id: GO:0090177
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.","definition_xrefs":["GOC:ascb_2009","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of planar polarity of embryonic epithelium","termid":"GO:0042249"},{"relation_name":"is_a","term_name":"embryonic morphogenesis","termid":"GO:0048598"},{"relation_name":"part_of","term_name":"neural tube closure","termid":"GO:0001843"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"establishment of planar polarity involved in neural tube closure","termid":"GO:0090177"}


id: PBO:0003502
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"telomere cap complex subunit Stn1","termid":"PBO:0003502"}


id: FYPO:0004325
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 5-fluorouracil. Cells stop growing (and may die) at a concentration of 5-fluorouracil that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0005447","FYPO:0002683","FYPO:0001985","FYPO:0000003"],"is_obsolete":false,"name":"sensitive to 5-fluorouracil","synonyms":[{"name":"hypersensitive to 5-fluorouracil","type":"exact"},{"name":"sensitive to 5-FU","type":"exact"},{"name":"sensitive to 5-fluorouracil during mitotic cell cycle","type":"related"},{"name":"sensitive to 5-fluorouracil during vegetative growth","type":"exact"}],"termid":"FYPO:0004325"}


id: PBO:0028080
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-multiple_mitotic_spindles","termid":"PBO:0028080"}


id: GO:1905072
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart.","definition_xrefs":["GOC:TermGenie","PMID:10645959","GOC:rl","GOC:BHF","GO_REF:0000094","PMID:16314491","PMID:19703439"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tissue development","termid":"GO:0009888"},{"relation_name":"part_of","term_name":"heart development","termid":"GO:0007507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cardiac jelly development","synonyms":[{"name":"heart cardiac jelly development","type":"exact"}],"termid":"GO:1905072"}


id: MONDO:0957791
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder with motor regression, progressive spastic paraplegia, and oromotor dysfunction","secondary_identifiers":["OMIM:620515","MEDGEN:1846192","UMLS:C5882695"],"termid":"MONDO:0957791","xrefs":{"Monarch":{"xref_id":"0957791"}}}


id: PBO:0058776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 7110","termid":"PBO:0058776"}


id: GO:0035371
data:
  {"annotated_genes":["SJAG_02045","SJAG_02040","SJAG_01613","SJAG_02336","SJAG_01196","SJAG_02695","SJAG_00113","SJAG_00723","SJAG_02624","SJAG_00030","SJAG_00851","SJAG_03052","SJAG_02761","SJAG_03540","SJAG_00140"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[71018,79832,80263,99572,105013,119910],"is_not":false,"summary":null,"term":"GO:0035371"},{"annotations":[97930,104105,95566],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903754"},{"annotations":[97327,100731,114420,89980,104243,119032,102677],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904511"}]},"cv_name":"cellular_component","definition":"The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.","definition_xrefs":["PMID:12700769","GOC:lb","GOC:bf","PMID:16643273"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule end","termid":"GO:1990752"}],"gene_count":15,"genes_by_uniquename":{"SJAG_00030":null,"SJAG_00113":null,"SJAG_00140":null,"SJAG_00723":null,"SJAG_00851":null,"SJAG_01196":null,"SJAG_01613":null,"SJAG_02040":null,"SJAG_02045":null,"SJAG_02336":null,"SJAG_02624":null,"SJAG_02695":null,"SJAG_02761":null,"SJAG_03052":null,"SJAG_03540":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0015630"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0015630","GO:0005575"],"is_obsolete":false,"name":"microtubule plus-end","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"PMID:30726171":null},"synonyms":[{"name":"growing microtubule plus end","type":"exact"},{"name":"microtubule plus end","type":"exact"}],"termid":"GO:0035371","terms_by_termid":{"GO:0035371":null,"GO:1903754":null,"GO:1904511":null}}


id: GO:0018578
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.","definition_xrefs":["EC:1.13.11.3"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","termid":"GO:0016702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"protocatechuate 3,4-dioxygenase activity","secondary_identifiers":["UM-BBD_reactionID:r0143","MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN","RHEA:10084"],"synonyms":[{"name":"protocatechuate oxygenase activity","type":"broad"},{"name":"protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)","type":"related"},{"name":"protocatechuic 3,4-dioxygenase activity","type":"related"},{"name":"protocatechuic 3,4-oxygenase activity","type":"related"},{"name":"protocatechuic acid oxidase activity","type":"related"}],"termid":"GO:0018578"}


id: PBO:0063821
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pleckstrin homology like domain family B member 3","termid":"PBO:0063821"}


id: MONDO:0030361
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A type I interferonopathy characterized by severe developmental delay and progressive neurologic deterioration ending in premature death. Brain imaging shows diffusely abnormal white matter, severe cerebral atrophy, and intracranial calcification.","definition_xrefs":["PMID:33230297"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Aicardi-Goutieres syndrome","termid":"MONDO:0018866"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005046","MONDO:0005559"],"is_obsolete":false,"name":"Aicardi-Goutieres syndrome 8","secondary_identifiers":["OMIM:619486","MEDGEN:1790409","UMLS:C5551352"],"synonyms":[{"name":"AGS8","type":"exact"},{"name":"Aicardi-Goutieres syndrome 8","type":"exact"}],"termid":"MONDO:0030361","xrefs":{"Monarch":{"xref_id":"0030361"}}}


id: MONDO:0003160
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. An adenocarcinoma with sebaceous differentiation. It presents as a painless mass and it may be multifocal. It grows in the ocular adnexae and in the skin of head and neck, trunk, genitals, and extremities. It is characterized by the presence of malignant cells with multivesicular and clear cytoplasm. It may recur and metastasize.","definition_xrefs":["NCIT:C40310"],"gene_count":0,"genotype_count":0,"name":"obsolete sebaceous carcinoma (obsolete MONDO:0003160)","termid":"MONDO:0003160","xrefs":{"Monarch":{"xref_id":"0003160"}}}


id: PBO:0026751
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cellular_response_to_stress","termid":"PBO:0026751"}


id: PBO:0056924
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIOS divergent transcript","termid":"PBO:0056924"}


id: GO:0043468
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose.","definition_xrefs":["GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"is_a","term_name":"regulation of small molecule metabolic process","termid":"GO:0062012"},{"relation_name":"regulates","term_name":"fucose catabolic process","termid":"GO:0019317"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"regulation of fucose catabolic process","termid":"GO:0043468"}


id: PBO:0067384
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 488, pseudogene","termid":"PBO:0067384"}


id: PBO:0051198
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 3/OR16-16 (pseudogene)","termid":"PBO:0051198"}


id: MONDO:0008919
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Systemic primary carnitine deficiency (SPCD) is a potentially lethal disorder of fatty acid oxidation characterized classically by early childhood onset cardiomyopathy often with weakness and hypotonia, failure to thrive and recurrent hypoglycemic hypoketotic seizures and/or coma.","definition_xrefs":["Orphanet:158"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of amino acid metabolism","termid":"MONDO:0004736"},{"relation_name":"is_a","term_name":"disorder of fatty acid oxidation and ketogenesis","termid":"MONDO:0017713"},{"relation_name":"is_a","term_name":"disorder of carnitine cycle and carnitine transport","termid":"MONDO:0017716"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0004736","MONDO:0005066"],"is_obsolete":false,"name":"systemic primary carnitine deficiency disease","secondary_identifiers":["ICD9:277.82","ICD9:277.81","NANDO:1200973","OMIM:212140","NANDO:2200508","GARD:5104","NCIT:C98864","MEDGEN:90999","SCTID:21764004","MESH:C536778","UMLS:C0342788","DOID:14365"],"synonyms":[{"name":"CARNITINE deficiency, systemic primary","type":"related"},{"name":"CDSP","type":"exact"},{"name":"CUD","type":"exact"},{"name":"Carnitine deficiency","type":"exact"},{"name":"Carnitine deficiency, primary","type":"related"},{"name":"Carnitine deficiency, systemic, due to defect in renal reabsorption of Carnitine","type":"related"},{"name":"Carnitine deficiency, systemic, due to defect in renal reabsorption of carnitine","type":"related"},{"name":"Carnitine plasma-membrane transporter deficiency","type":"related"},{"name":"Carnitine transporter defect","type":"exact"},{"name":"Carnitine transporter, plasma-Membrane, deficiency of","type":"related"},{"name":"Carnitine uptake defect","type":"related"},{"name":"Carnitine uptake deficiency","type":"exact"},{"name":"SPCD","type":"exact"},{"name":"carnitine transporter deficiency","type":"exact"},{"name":"carnitine uptake defect","type":"exact"},{"name":"cud","type":"exact"},{"name":"deficiency of plasma-membrane carnitine transporter","type":"exact"},{"name":"primary carnitine deficiency","type":"exact"},{"name":"renal carnitine transport defect","type":"exact"},{"name":"systemic Carnitine deficiency","type":"related"},{"name":"systemic primary carnitine deficiency","type":"related"},{"name":"systemic primary carnitine deficiency disease","type":"exact"}],"termid":"MONDO:0008919","xrefs":{"Monarch":{"xref_id":"0008919"}}}


id: PBO:0050775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histatin 3","termid":"PBO:0050775"}


id: PBO:0003008
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER unfolded protein response protein (predicted)","termid":"PBO:0003008"}


id: PBO:0044514
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CXXC motif containing zinc binding protein","termid":"PBO:0044514"}


id: GO:0004973
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete N-methyl-D-aspartate receptor-associated protein activity (obsolete GO:0004973)","synonyms":[{"name":"N-methyl-D-aspartate receptor-associated protein activity","type":"exact"}],"termid":"GO:0004973"}


id: GO:1902135
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol.","definition_xrefs":["GOC:TermGenie","PMID:9872995","PMID:15949826"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lignan biosynthetic process","termid":"GO:0009807"},{"relation_name":"is_a","term_name":"diol biosynthetic process","termid":"GO:0034312"},{"relation_name":"is_a","term_name":"phenol-containing compound biosynthetic process","termid":"GO:0046189"},{"relation_name":"is_a","term_name":"(+)-secoisolariciresinol metabolic process","termid":"GO:1902133"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"(+)-secoisolariciresinol biosynthetic process","synonyms":[{"name":"(+)-secoisolariciresinol anabolism","type":"exact"},{"name":"(+)-secoisolariciresinol biosynthesis","type":"exact"},{"name":"(+)-secoisolariciresinol formation","type":"exact"},{"name":"(+)-secoisolariciresinol synthesis","type":"exact"}],"termid":"GO:1902135"}


id: GO:0052122
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete negative aerotaxis in host environment (obsolete GO:0052122)","synonyms":[{"name":"negative aerotaxis in response to host environment","type":"exact"}],"termid":"GO:0052122"}


id: GO:1902019
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.","definition_xrefs":["GOC:jl","GOC:TermGenie","GOC:cilia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell motility","termid":"GO:2000145"},{"relation_name":"regulates","term_name":"cilium-dependent cell motility","termid":"GO:0060285"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cilium-dependent cell motility","synonyms":[{"name":"regulation of ciliary cell motility","type":"related"},{"name":"regulation of cilium cell motility","type":"exact"}],"termid":"GO:1902019"}


id: PR:P79088
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein transport protein Sec61 subunit alpha isoform 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02501","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein transport protein sec61 subunit alpha (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC354.02c","secondary_identifiers":["UniProtKB:P79088"],"synonyms":[{"name":"Spom972h-SEC61A1","type":"exact"}],"termid":"PR:P79088"}


id: GO:0046262
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete nitrotoluene biosynthetic process (obsolete GO:0046262)","synonyms":[{"name":"nitrotoluene anabolism","type":"exact"},{"name":"nitrotoluene biosynthesis","type":"exact"},{"name":"nitrotoluene biosynthetic process","type":"exact"},{"name":"nitrotoluene formation","type":"exact"},{"name":"nitrotoluene synthesis","type":"exact"}],"termid":"GO:0046262"}


id: PBO:0043022
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"charged multivesicular body protein 1A pseudogene 1","termid":"PBO:0043022"}


id: MONDO:0001782
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cataract that produces swelling and opacity of the entire lens; cataracts are removed before maturity.","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"senile cataract","termid":"MONDO:0004847"},{"relation_name":"is_a","term_name":"cataract","termid":"MONDO:0005129"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"mature cataract","secondary_identifiers":["SCTID:849000","DOID:13717","ICD9:366.17","UMLS:C3665439","MEDGEN:784053"],"synonyms":[{"name":"total or mature cataract","type":"exact"},{"name":"total, mature senile cataract","type":"exact"}],"termid":"MONDO:0001782","xrefs":{"Monarch":{"xref_id":"0001782"}}}


id: PBO:0065933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rac family small GTPase 1 pseudogene 7","termid":"PBO:0065933"}


id: PBO:0061836
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"opioid growth factor receptor","termid":"PBO:0061836"}


id: PBO:0005209
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complements S. cerevisiae PET127","termid":"PBO:0005209"}


id: GO:0030445
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.","definition_xrefs":["GOC:mcc","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fungal-type cell wall","termid":"GO:0009277"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005618"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005618"],"is_obsolete":false,"name":"yeast-form cell wall","termid":"GO:0030445"}


id: FYPO:0001470
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0002058","FYPO:0002057","FYPO:0000003","FYPO:0002060","FYPO:0000139"],"is_obsolete":false,"name":"normal growth on tacrolimus","synonyms":[{"name":"normal cell population growth in presence of tacrolimus","type":"exact"},{"name":"normal cell population growth on tacrolimus","type":"exact"},{"name":"normal cellular response to FK506","type":"exact"},{"name":"normal cellular response to tacrolimus","type":"related"},{"name":"normal vegetative cell population growth on tacrolimus","type":"exact"}],"termid":"FYPO:0001470"}


id: GO:0030744
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H+.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete luteolin O-methyltransferase activity (obsolete GO:0030744)","termid":"GO:0030744"}


id: PBO:0083434
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YKR041W","termid":"PBO:0083434"}


id: PBO:0078469
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-His (anticodon GTG) 1-7","termid":"PBO:0078469"}


id: PBO:0113091
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytosolic aspartate aminotransferase involved in the metabolism of nitrogen and amino acids such as aspartate; localizes to and functions in peroxisomes in oleate-grown cells; moonlighting role as a ribosome-associated protein that modulates translation in response to stress","termid":"PBO:0113091"}


id: GO:0039020
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.","definition_xrefs":["PMID:19909807","GOC:mtg_kidney_jan10","PMID:9268568"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nephron tubule development","termid":"GO:0072080"},{"relation_name":"part_of","term_name":"pronephric nephron development","termid":"GO:0039019"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"pronephric nephron tubule development","termid":"GO:0039020"}


id: GO:0051554
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.","definition_xrefs":["PMID:11402179"],"direct_ancestors":[{"relation_name":"is_a","term_name":"flavone metabolic process","termid":"GO:0051552"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"flavonol metabolic process","synonyms":[{"name":"flavonol metabolism","type":"exact"}],"termid":"GO:0051554"}


id: PBO:0005321
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Tim9-Tim10 complex subunit Tim9 (predicted)","termid":"PBO:0005321"}


id: PBO:0062178
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"OR4M2 overlapping transcript 1","termid":"PBO:0062178"}


id: GO:0048616
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.","definition_xrefs":["GOC:jid","GOC:rc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-embryonic animal morphogenesis","termid":"GO:0009886"},{"relation_name":"part_of","term_name":"anterior midgut (ectodermal) morphogenesis","termid":"GO:0007441"},{"relation_name":"part_of","term_name":"post-embryonic ectodermal digestive tract morphogenesis","termid":"GO:0048614"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"post-embryonic anterior midgut (ectodermal) morphogenesis","termid":"GO:0048616"}


id: MONDO:0054581
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Townes-Brocks syndrome","termid":"MONDO:0007142"},{"relation_name":"is_a","term_name":"polydactyly-syndactyly-triphalangism","termid":"MONDO:0800066"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"Townes-Brocks syndrome 1","secondary_identifiers":["UMLS:C4551481","OMIM:107480","MEDGEN:1635275"],"synonyms":[{"name":"TBS1","type":"related"},{"name":"Townes-Brocks syndrome 1","type":"exact"},{"name":"Townes-Brocks-branchiootorenal-like syndrome","type":"related"},{"name":"anus, imperforate, with hand, Foot, and Ear anomalies","type":"related"},{"name":"deafness, sensorineural, with imperforate anus and thumb anomalies","type":"related"},{"name":"rear syndrome","type":"related"},{"name":"renal-ear-anal-radial syndrome","type":"related"},{"name":"townes-brocks branchiootorenal-like syndrome","type":"exact"}],"termid":"MONDO:0054581","xrefs":{"Monarch":{"xref_id":"0054581"}}}


id: PATO:0000616
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A symmetry quality inhering in a bearer by virtue of the bearer's lacking symmetry.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symmetry","termid":"PATO:0000965"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"asymmetrical","synonyms":[{"name":"asymmetric","type":"exact"},{"name":"asymmetry","type":"exact"}],"termid":"PATO:0000616"}


id: PBO:0000248
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase (predicted)","termid":"PBO:0000248"}


id: PBO:0029554
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_ethyl_methanesulfonate","termid":"PBO:0029554"}


id: GO:0015817
data:
  {"annotated_genes":["SJAG_03256","SJAG_03400"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[97711],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0089708"},{"annotations":[104196],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090513"}]},"cv_name":"biological_process","definition":"The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"basic amino acid transport","termid":"GO:0015802"},{"relation_name":"is_a","term_name":"carboxylic acid transport","termid":"GO:0046942"},{"relation_name":"is_a","term_name":"nitrogen compound transport","termid":"GO:0071705"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03256":null,"SJAG_03400":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"histidine transport","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"L-histidine transport","type":"narrow"}],"termid":"GO:0015817","terms_by_termid":{"GO:0089708":null,"GO:0090513":null}}


id: GO:2000418
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of eosinophil migration.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of leukocyte migration","termid":"GO:0002687"},{"relation_name":"is_a","term_name":"regulation of eosinophil migration","termid":"GO:2000416"},{"relation_name":"positively_regulates","term_name":"eosinophil migration","termid":"GO:0072677"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of eosinophil migration","termid":"GO:2000418"}


id: PBO:0082731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the Rpd3L histone deacetylase complex; involved in histone deacetylation; protein abundance increases in response to DNA replication stress","termid":"PBO:0082731"}


id: PBO:0108552
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clr6 associated factor 1 Laf1","termid":"PBO:0108552"}


id: PBO:0038976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ADPGK antisense RNA 1","termid":"PBO:0038976"}


id: FYPO:0004580
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a cell contains a larger number plasmid catenanes than normal. Plasmid catenanes are structures formed by two or more copies of a circular plasmid DNA molecule catenated together.","definition_xrefs":["PomBase:mah","PMID:15957215"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vegetative cell phenotype","termid":"FYPO:0003755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"increased number of plasmid catenanes","synonyms":[{"name":"increased number of catenated plasmids","type":"exact"},{"name":"increased number of plasmid catenanes during mitotic cell cycle","type":"related"},{"name":"increased number of plasmid catenanes during vegetative growth","type":"exact"},{"name":"increased plasmid catenane level","type":"exact"}],"termid":"FYPO:0004580"}


id: GO:0061903
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.","definition_xrefs":["GOC:bc","GOC:aruk","PMID:18723082"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of 1-phosphatidylinositol-3-kinase activity (obsolete GO:0061903)","termid":"GO:0061903"}


id: GO:0005951
data:
  {"annotated_genes":["SJAG_00392","SJAG_00412"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[70696,106888],"is_not":false,"summary":null,"term":"GO:0005951"}]},"cv_name":"cellular_component","definition":"A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.","definition_xrefs":["PMID:8626695"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00392":null,"SJAG_00412":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0032991","GO:0005737","GO:0005575"],"is_obsolete":false,"name":"carbamoyl-phosphate synthase complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"arginine-specific carbamoyl phosphate synthetase complex","type":"narrow"},{"name":"carbamoyl phosphate synthase complex","type":"exact"},{"name":"carbamoyl-phosphate synthase arginine-specific complex","type":"narrow"}],"termid":"GO:0005951","terms_by_termid":{"GO:0005951":null}}


id: PR:O42951
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- abz2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O42951"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aminodeoxychorismate lyase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC19G7.02","synonyms":[{"name":"4-amino-4-deoxychorismate lyase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ADC lyase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ADCL (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-abz2","type":"exact"}],"termid":"PR:O42951"}


id: FYECO:0000140
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"The experiment was carried out in vitro.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping experimental environment","termid":"FYECO:0000132"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"in vitro","termid":"FYECO:0000140"}


id: PBO:0043131
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CBY1 interacting BAR domain containing 2","termid":"PBO:0043131"}


id: MONDO:1011007
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Peripheral neuropathy that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peripheral neuropathy, non-human animal","termid":"MONDO:1010239"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peripheral neuropathy, dog","secondary_identifiers":["OMIA:001150-9615"],"termid":"MONDO:1011007","xrefs":{"Monarch":{"xref_id":"1011007"}}}


id: PBO:0066859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 159","termid":"PBO:0066859"}


id: SOFP:finished
data:
  {"annotation_feature_type":"gene","cv_name":"feature_property","definition":"If the annotation of the feature is complete","definition_xrefs":["so:sjc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"feature_property","termid":"SOFP:feature_property"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"finished","termid":"SOFP:finished"}


id: FYPO:0002486
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the occurrence of meiotic strand displacement is decreased. Meiotic strand displacement is the part of meiotic recombination in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected.","definition_xrefs":["GO:0000714","PomBase:mah","PMID:22723423"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal meiotic recombination","termid":"FYPO:0000008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000293","FYPO:0000631","FYPO:0000002","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"decreased meiotic strand displacement","synonyms":[{"name":"decreased D-loop unwinding","type":"related"},{"name":"decreased meiotic D-loop dissociation","type":"exact"},{"name":"decreased meiotic D-loop processing","type":"related"},{"name":"reduced meiotic strand displacement","type":"exact"}],"termid":"FYPO:0002486"}


id: GO:0016890
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete site-specific endodeoxyribonuclease activity, specific for altered base (obsolete GO:0016890)","termid":"GO:0016890"}


id: MONDO:0012597
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"prostate cancer, hereditary","termid":"MONDO:0700275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"prostate cancer, hereditary, 9","secondary_identifiers":["GARD:15505","UMLS:C1970250","MESH:C567031","OMIM:610997","MEDGEN:369689"],"synonyms":[{"name":"HPC9","type":"related"},{"name":"prostate cancer, hereditary, 9","type":"exact"},{"name":"prostate cancer, hereditary, type 9","type":"exact"}],"termid":"MONDO:0012597","xrefs":{"Monarch":{"xref_id":"0012597"}}}


id: PBO:0038397
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_during","termid":"PBO:0038397"}


id: MONDO:0957266
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RECON progeroid syndrome","secondary_identifiers":["OMIM:620370","UMLS:C5830504","MEDGEN:1841140"],"termid":"MONDO:0957266","xrefs":{"Monarch":{"xref_id":"0957266"}}}


id: GO:0120326
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:22589729","GOC:krc","PMID:14731267","GOC:ach"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont entry into host","termid":"GO:0044409"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"appressorium-mediated entry into host","synonyms":[{"name":"appressorium-mediated host invasion","type":"exact"},{"name":"appressorium-mediated host penetration","type":"exact"},{"name":"appressorium-mediated invasion into host","type":"exact"},{"name":"appressorium-mediated penetration into host","type":"exact"}],"termid":"GO:0120326"}


id: MONDO:0013059
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Aicardi-Goutieres syndrome in which the cause of the disease is a mutation in the SAMHD1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Aicardi-Goutieres syndrome","termid":"MONDO:0018866"},{"relation_name":"is_a","term_name":"SAMHD1-related type 1 interferonopathy","termid":"MONDO:0700260"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0006025","MONDO:0005559"],"is_obsolete":false,"name":"Aicardi-Goutieres syndrome 5","secondary_identifiers":["MESH:C535608","NANDO:2200897","NCIT:C168564","OMIM:612952","GARD:10151","UMLS:C2749659","MEDGEN:413116"],"synonyms":[{"name":"AGS5","type":"related"},{"name":"Aicardi-Goutieres syndrome 5","type":"exact"},{"name":"Aicardi-Goutieres syndrome caused by mutation in SAMHD1","type":"exact"},{"name":"Aicardi-Goutieres syndrome type 5","type":"exact"},{"name":"SAMHD1 Aicardi-Goutieres syndrome","type":"exact"},{"name":"SAMHD1-related Aicardi-Goutieres syndrome","type":"related"}],"termid":"MONDO:0013059","xrefs":{"Monarch":{"xref_id":"0013059"}}}


id: FYPO:0008089
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which mitochondrion fusion is abnormal.","definition_xrefs":["PMID:37590302"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular component organization","termid":"FYPO:0000335"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"abnormal mitochondrial fusion","termid":"FYPO:0008089"}


id: PBO:0078410
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Gly (CCC) 4-1","termid":"PBO:0078410"}


id: MONDO:0007113
data:
  {"annotated_genes":["SJAG_02279"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86041],"is_not":false,"summary":null,"term":"MONDO:0007113"}]},"cv_name":"mondo","definition":"A neurogenetic disorder characterized by severe intellectual deficit and distinct facial dysmorphic features.","definition_xrefs":["Orphanet:72"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"excluded_subClassOf","term_name":"epilepsy","termid":"MONDO:0005027"},{"relation_name":"excluded_subClassOf","term_name":"chromosomal disorder","termid":"MONDO:0019040"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02279":null},"genotype_count":0,"is_obsolete":false,"name":"Angelman syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C75462","icd11.foundation:1106558408","ICD9:759.89","MESH:C531619","DECIPHER:54","MedDRA:10049004","DOID:1932","GARD:5810","ICD10CM:Q93.51","MESH:D017204","OMIM:105830","SCTID:76880004","DECIPHER:4","NANDO:2200960","MEDGEN:58144","NANDO:1200686","UMLS:C0162635"],"synonyms":[{"name":"AS","type":"related"},{"name":"Angelman syndrome","type":"exact"},{"name":"Angelman syndrome (Type 1)","type":"narrow"},{"name":"Angelman syndrome (Type 2)","type":"narrow"},{"name":"Angelman syndrome chromosome region","type":"related"},{"name":"Angelman’s syndrome","type":"exact"},{"name":"happy puppet syndrome","type":"exact"},{"name":"happy puppet syndrome (formerly)","type":"related"},{"name":"happy puppet syndrome, formerly","type":"related"},{"name":"puppetlike syndrome","type":"exact"}],"termid":"MONDO:0007113","terms_by_termid":{"MONDO:0007113":null},"xrefs":{"Monarch":{"xref_id":"0007113"}}}


id: MONDO:1011716
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"metabolic disease, non-human animal","termid":"MONDO:1011331"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome, non-human animal","secondary_identifiers":["OMIA:001290"],"termid":"MONDO:1011716","xrefs":{"Monarch":{"xref_id":"1011716"}}}


id: GO:0045710
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism.","definition_xrefs":["GOC:go_curators","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of salivary gland boundary specification","termid":"GO:0045705"},{"relation_name":"is_a","term_name":"regulation of larval salivary gland boundary specification","termid":"GO:0045708"},{"relation_name":"negatively_regulates","term_name":"larval salivary gland boundary specification","termid":"GO:0007433"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of larval salivary gland boundary specification","synonyms":[{"name":"down regulation of larval salivary gland determination","type":"exact"},{"name":"down-regulation of larval salivary gland determination","type":"exact"},{"name":"downregulation of larval salivary gland determination","type":"exact"},{"name":"inhibition of larval salivary gland determination","type":"narrow"},{"name":"negative regulation of larval salivary gland determination","type":"exact"}],"termid":"GO:0045710"}


id: GO:0030317
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.","definition_xrefs":["GOC:TermGenie","GOC:cilia","GO_REF:0000060","GOC:krc","PMID:26680031"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cilium-dependent cell motility","termid":"GO:0060285"},{"relation_name":"is_a","term_name":"cilium movement involved in cell motility","termid":"GO:0060294"},{"relation_name":"is_a","term_name":"sperm motility","termid":"GO:0097722"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"flagellated sperm motility","secondary_identifiers":["GO:0097724","GO:1905419","Wikipedia:Sperm_motility"],"synonyms":[{"name":"flagellated sperm movement","type":"exact"},{"name":"sperm flagellum movement","type":"exact"},{"name":"sperm flagellum movement involved in flagellated sperm motility","type":"exact"},{"name":"sperm flagellum movement involved in flagellated sperm movement","type":"exact"},{"name":"sperm motility","type":"broad"},{"name":"sperm movement","type":"broad"}],"termid":"GO:0030317"}


id: PATO:0000441
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A quality of a single process inhering in a bearer by virtue of the bearer's marked by tedious repetition.","definition_xrefs":["thefreedictionary.com:thefreedictionary.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"occurrence","termid":"PATO:0000057"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"repetitive","termid":"PATO:0000441"}


id: PR:O13808
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A glia maturation factor beta that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00830","PANTHER:PTHR11249:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin-depolymerizing factor gmf1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC17H9.11","secondary_identifiers":["UniProtKB:O13808"],"synonyms":[{"name":"Spom972h-GMFB","type":"exact"},{"name":"glia maturation factor-like protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O13808"}


id: GO:1901951
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.","definition_xrefs":["GOC:kmv","PMID:23358451","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of vesicle transport along microtubule","termid":"GO:1901608"},{"relation_name":"is_a","term_name":"regulation of dense core granule transport","termid":"GO:1904809"},{"relation_name":"regulates","term_name":"anterograde neuronal dense core vesicle transport","termid":"GO:1990048"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of anterograde dense core granule transport","termid":"GO:1901951"}


id: PBO:0071227
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L23a pseudogene 68","termid":"PBO:0071227"}


id: MONDO:0017730
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"metachromatic leukodystrophy, juvenile form","termid":"MONDO:0009591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002039","MONDO:0002525","MONDO:0002561","MONDO:0005244","MONDO:0005559"],"is_obsolete":false,"name":"metachromatic leukodystrophy, adult form","secondary_identifiers":["MEDGEN:199625","GARD:21330","NANDO:2201204","Orphanet:309271","NANDO:1200081","UMLS:C0751279","SCTID:24326000"],"synonyms":[{"name":"MLD, adult form","type":"exact"},{"name":"arylsulfatase A deficiency, adult form","type":"exact"}],"termid":"MONDO:0017730","xrefs":{"Monarch":{"xref_id":"0017730"}}}


id: MONDO:0008712
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acrocraniofacial dysostosis is a very rare form of acrofacial dyosotosis, reported in two sisters to date, characterized by short stature, acrocephaly, ocular hypertelorism, ptosis of eyelids, ocular proptosis, downslanting palpebral fissures, high nasal bridge, anteverted nostrils, short philtrum, cleft palate, micrognathia, abnormal external ears, preauricular pits, mixed hearing loss, bulbous digits, metatarsus varus, pectus excavatum and various radiological abnormalities. Features of this syndrome were reported to overlap with otopalatodigital syndrome types 1 and 2. There have been no further descriptions in the literature since 1988.","definition_xrefs":["Orphanet:949"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"acrofacial dysostosis","termid":"MONDO:0018237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"acrocraniofacial dysostosis","secondary_identifiers":["MEDGEN:349738","SCTID:720418008","MESH:C536892","OMIM:201050","UMLS:C1860145","GARD:3075"],"synonyms":[{"name":"Kaplan Plauchu Fitch syndrome","type":"related"},{"name":"Kaplan-Plauchu-Fitch syndrome","type":"exact"},{"name":"acrocraniofacial dysostosis","type":"exact"}],"termid":"MONDO:0008712","xrefs":{"Monarch":{"xref_id":"0008712"}}}


id: GO:0031153
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.","definition_xrefs":["ISBN:0521583640","GOC:mah","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"socially cooperative development","termid":"GO:0099120"},{"relation_name":"part_of","term_name":"sorocarp development","termid":"GO:0030587"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"slug development involved in sorocarp development","synonyms":[{"name":"migratory slug development during sorocarp development","type":"narrow"},{"name":"pseudoplasmodium biosynthesis","type":"exact"},{"name":"pseudoplasmodium formation","type":"exact"},{"name":"slug development during fruiting body development","type":"exact"},{"name":"slug development during sorocarp development","type":"related"},{"name":"standing slug development during sorocarp development","type":"narrow"}],"termid":"GO:0031153"}


id: PBO:0090150
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"LEM domain nuclear inner membrane protein Man1, Sad1 interacting factor","termid":"PBO:0090150"}


id: MONDO:0019904
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ring chromosome 3 syndrome is a rare chromosomal anomaly syndrome with a highly variable phenotype principally characterized by pre- and postnatal growth retardation, short stature, developmental delay, mild to severe intellectual disability, microcephaly and mild dysmorphic features (incl. triangular face, dysplastic ears, upslanting palpebral fissures, epicanthic folds, broad nasal bridge, full nasal tip, long philtrum, downturned corners of the mouth, and micro/retrognathia). Additional manifestations reported include hypotonia, mild articular limitation, hearing loss, digital anomalies (i.e. clinodacytyly, brachydactyly), café-au-lait patches and hypospadias.","definition_xrefs":["Orphanet:96172"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome 3 disorder","termid":"MONDO:0700010"},{"relation_name":"is_a","term_name":"ring chromosome disorder","termid":"MONDO:0700091"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring chromosome 3","secondary_identifiers":["UMLS:C4707449","SCTID:765486004","MEDGEN:1643677","NCIT:C121982","GARD:10839"],"synonyms":[{"name":"R3","type":"related"},{"name":"Ring 3","type":"related"},{"name":"Ring chromosome 3 syndrome","type":"related"},{"name":"Ring chromosome type 3","type":"exact"},{"name":"chromosome 3 ring","type":"related"},{"name":"rose cluster 3","type":"exact"}],"termid":"MONDO:0019904","xrefs":{"Monarch":{"xref_id":"0019904"}}}


id: FYPO:0001305
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of any long-chain fatty acid-CoA ligase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal catalytic activity","termid":"FYPO:0000661"},{"relation_name":"is_a","term_name":"abnormal metabolic process","termid":"FYPO:0000860"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000002","FYPO:0000707","FYPO:0001985","FYPO:0005447","FYPO:0000661","FYPO:0000654"],"is_obsolete":false,"name":"abnormal long-chain fatty acid-CoA ligase activity","synonyms":[{"name":"abnormal lcfa-ligase activity","type":"exact"}],"termid":"FYPO:0001305"}


id: PBO:0082746
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of the RSC chromatin remodeling complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; null mutants are osmosensitive; RSC30 has a paralog, RSC3, that arose from the whole genome duplication","termid":"PBO:0082746"}


id: GO:0030346
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a protein phosphatase 2B.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein phosphatase binding","termid":"GO:0019903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"protein phosphatase 2B binding","synonyms":[{"name":"calcineurin binding","type":"exact"},{"name":"protein phosphatase 3 binding","type":"related"}],"termid":"GO:0030346"}


id: GO:0008282
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity.","definition_xrefs":["GOC:bhm","PMID:16308567","PMID:16956886"],"direct_ancestors":[{"relation_name":"is_a","term_name":"potassium channel complex","termid":"GO:0034705"},{"relation_name":"is_a","term_name":"plasma membrane protein complex","termid":"GO:0098797"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005886","GO:0032991"],"is_obsolete":false,"name":"inward rectifying potassium channel","synonyms":[{"name":"ATP-sensitive potassium channel complex","type":"exact"},{"name":"KCNJ11-SUR complex","type":"related"},{"name":"KCNJ11-SURx complex","type":"related"},{"name":"KCNJ8-SUR complex","type":"related"},{"name":"KCNJ8-SURx complex","type":"related"},{"name":"Kir6-SUR complex","type":"related"},{"name":"Kir6.1-SUR complex","type":"related"},{"name":"Kir6.1-SURx complex","type":"related"},{"name":"Kir6.2-SUR complex","type":"related"},{"name":"Kir6.2-SURx complex","type":"related"},{"name":"Kir6.x complex","type":"related"},{"name":"Kir6.x-SURx complex","type":"related"},{"name":"inward rectifying K+ channel","type":"exact"}],"termid":"GO:0008282"}


id: PBO:0066762
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 60","termid":"PBO:0066762"}


id: GO:0160082
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit].","definition_xrefs":["PMID:11595184","PMID:11598268"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-proline 4-dioxygenase activity","termid":"GO:0031545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0140096","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"hypoxia-inducible factor-proline dioxygenase activity","secondary_identifiers":["RHEA:48400","EC:1.14.11.29"],"synonyms":[{"name":"HIF hydroxylase","type":"broad"},{"name":"HIF prolyl hydroxylase","type":"exact"}],"termid":"GO:0160082"}


id: GO:0072274
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glomerular basement membrane development","termid":"GO:0032836"},{"relation_name":"part_of","term_name":"metanephric glomerulus development","termid":"GO:0072224"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric glomerular basement membrane development","termid":"GO:0072274"}


id: PBO:0065119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein kinase C substrate 80K-H","termid":"PBO:0065119"}


id: PBO:0042350
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CD84 molecule","termid":"PBO:0042350"}


id: MONDO:1011167
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Osteochondritis dissecans that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondritis dissecans, non-human animal","termid":"MONDO:1010298"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteochondritis dissecans, dog","secondary_identifiers":["OMIA:000748-9615"],"termid":"MONDO:1011167","xrefs":{"Monarch":{"xref_id":"1011167"}}}


id: MONDO:0020629
data:
  {"annotated_genes":["SJAG_03898","SJAG_04816"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87355],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008876"},{"annotations":[86784],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0020628"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":2,"genes_by_uniquename":{"SJAG_03898":null,"SJAG_04816":null},"genotype_count":0,"is_obsolete":false,"name":"microcephaly, growth restriction and increased sister chromatid exchange","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIMPS:210900"],"synonyms":[{"name":"MGRISCE","type":"exact"}],"termid":"MONDO:0020629","terms_by_termid":{"MONDO:0008876":null,"MONDO:0020628":null},"xrefs":{"Monarch":{"xref_id":"0020629"}}}


id: PBO:0056470
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule associated serine/threonine kinase like","termid":"PBO:0056470"}


id: PBO:0071755
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein lateral stalk subunit P1 pseudogene 2","termid":"PBO:0071755"}


id: MONDO:0056796
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Renal damage and impaired renal function secondary to urinary tract obstruction.","direct_ancestors":[{"relation_name":"is_a","term_name":"kidney disorder","termid":"MONDO:0005240"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"obstructive nephropathy","secondary_identifiers":["UMLS:C0149939","icd11.foundation:848128884","MEDGEN:508456","NCIT:C120902","DOID:0070314","ICD9:593.89","SCTID:86249007"],"synonyms":[{"name":"congenital obstructive nephropathy","type":"exact"},{"name":"obstructive nephropathy","type":"exact"}],"termid":"MONDO:0056796","xrefs":{"Monarch":{"xref_id":"0056796"}}}


id: PATO:0000168
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000168 relative time (obsolete PATO:0000168)","termid":"PATO:0000168"}


id: PBO:0061432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear receptor subfamily 1 group H member 5, pseudogene","termid":"PBO:0061432"}


id: PBO:0085332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Phosphatidylinositol transfer protein (PITP); downregulates Plb1p-mediated turnover of phosphatidylcholine; forms a complex with Psd2p which appears essential for maintenance of vacuolar PE levels; found in the cytosol and microsomes; homologous to Pdr16p; deletion affects phospholipid composition","termid":"PBO:0085332"}


id: PBO:0083921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Formylglycinamidine-ribonucleotide (FGAM)-synthetase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway","termid":"PBO:0083921"}


id: GO:0106340
data:
  {"annotated_genes":["SJAG_01269"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[66115],"is_not":false,"summary":null,"term":"GO:0106340"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 H+ + 2 S-adenosyl-L-homocysteine.","definition_xrefs":["RHEA:42396"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA (guanine) methyltransferase activity","termid":"GO:0016423"},{"relation_name":"is_a","term_name":"tRNA (cytidine) methyltransferase activity","termid":"GO:0016427"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01269":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140101"}],"interesting_parent_ids":["GO:0140098","GO:0003824","GO:0016741","GO:0003674","GO:0016740","GO:0140101"],"is_obsolete":false,"name":"tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["Reactome:R-HSA-9024161","EC:2.1.1.205"],"synonyms":[{"name":"tRNA (cytidine 32-2'-O)-methyltransferase activity","type":"narrow"},{"name":"tRNA (cytidine(32)-2'-O)-methyltransferase activity","type":"narrow"},{"name":"tRNA (guanosine 34-2'-O)-methyltransferase activity","type":"narrow"},{"name":"tRNA (guanosine(34)-2'-O)-methyltransferase activity","type":"narrow"}],"termid":"GO:0106340","terms_by_termid":{"GO:0106340":null}}


id: MONDO:0044956
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare carcinoma that arises from the paranasal sinus. It is characterized by the presence of epidermoid cells, mucus producing cells, and cells of intermediate type.","definition_xrefs":["NCIT:C6018"],"direct_ancestors":[{"relation_name":"is_a","term_name":"paranasal sinus carcinoma","termid":"MONDO:0000380"},{"relation_name":"is_a","term_name":"mucoepidermoid carcinoma","termid":"MONDO:0003036"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"paranasal sinus mucoepidermoid carcinoma","secondary_identifiers":["MEDGEN:235461","UMLS:C1335340"],"synonyms":[{"name":"accessory sinus mucoepidermoid carcinoma","type":"exact"},{"name":"mucoepidermoid carcinoma of accessory sinus","type":"exact"},{"name":"mucoepidermoid carcinoma of paranasal sinus","type":"exact"},{"name":"mucoepidermoid carcinoma of the accessory sinus","type":"exact"},{"name":"mucoepidermoid carcinoma of the paranasal sinus","type":"exact"},{"name":"paranasal sinus mucoepidermoid carcinoma","type":"exact"}],"termid":"MONDO:0044956","xrefs":{"Monarch":{"xref_id":"0044956"}}}


id: MONDO:0858986
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete autosomal dominant spastic paraplegia type 80 (obsolete MONDO:0858986)","termid":"MONDO:0858986","xrefs":{"Monarch":{"xref_id":"0858986"}}}


id: MONDO:1012416
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Kurosawa and Kusanagi hypercholesterolaemia, non-human animal","termid":"MONDO:1011718"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kurosawa and Kusanagi hypercholesterolaemia, rabbit","secondary_identifiers":["OMIA:001567-9986"],"termid":"MONDO:1012416","xrefs":{"Monarch":{"xref_id":"1012416"}}}


id: PBO:0064705
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase A pseudogene 41","termid":"PBO:0064705"}


id: GO:1902010
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.","definition_xrefs":["GOC:dph","GOC:TermGenie","PMID:10882126"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of translation in response to stress","termid":"GO:0032055"},{"relation_name":"is_a","term_name":"regulation of translation in response to endoplasmic reticulum stress","termid":"GO:0036490"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"negatively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"negative regulation of translation in response to endoplasmic reticulum stress","synonyms":[{"name":"down regulation of protein biosynthetic process involved in ER stress response","type":"exact"},{"name":"down regulation of protein biosynthetic process involved in response to ER stress","type":"exact"},{"name":"down regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"down-regulation of protein biosynthetic process involved in ER stress response","type":"exact"},{"name":"down-regulation of protein biosynthetic process involved in response to ER stress","type":"exact"},{"name":"down-regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"downregulation of protein biosynthetic process involved in ER stress response","type":"exact"},{"name":"downregulation of protein biosynthetic process involved in response to ER stress","type":"exact"},{"name":"downregulation of protein biosynthetic process involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"inhibition of protein biosynthetic process involved in ER stress response","type":"narrow"},{"name":"inhibition of protein biosynthetic process involved in response to ER stress","type":"narrow"},{"name":"inhibition of protein biosynthetic process involved in response to endoplasmic reticulum stress","type":"narrow"},{"name":"negative regulation of protein anabolism involved in ER stress response","type":"exact"},{"name":"negative regulation of protein anabolism involved in response to ER stress","type":"exact"},{"name":"negative regulation of protein anabolism involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"negative regulation of protein biosynthesis involved in ER stress response","type":"exact"},{"name":"negative regulation of protein biosynthesis involved in response to ER stress","type":"exact"},{"name":"negative regulation of protein biosynthesis involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"negative regulation of protein biosynthetic process involved in ER stress response","type":"exact"},{"name":"negative regulation of protein biosynthetic process involved in response to ER stress","type":"exact"},{"name":"negative regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"negative regulation of protein formation involved in ER stress response","type":"exact"},{"name":"negative regulation of protein formation involved in response to ER stress","type":"exact"},{"name":"negative regulation of protein formation involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"negative regulation of protein synthesis involved in ER stress response","type":"exact"},{"name":"negative regulation of protein synthesis involved in response to ER stress","type":"exact"},{"name":"negative regulation of protein synthesis involved in response to endoplasmic reticulum stress","type":"exact"},{"name":"negative regulation of translation involved in ER stress response","type":"exact"},{"name":"negative regulation of translation involved in response to ER stress","type":"exact"},{"name":"protein biosynthesis inhibitor activity involved in ER stress response","type":"related"},{"name":"protein biosynthesis inhibitor activity involved in response to ER stress","type":"related"},{"name":"protein biosynthesis inhibitor activity involved in response to endoplasmic reticulum stress","type":"related"},{"name":"protein biosynthetic process inhibitor activity involved in ER stress response","type":"related"},{"name":"protein biosynthetic process inhibitor activity involved in response to ER stress","type":"related"},{"name":"protein biosynthetic process inhibitor activity involved in response to endoplasmic reticulum stress","type":"related"}],"termid":"GO:1902010"}


