# terms

id: PBO:0046192
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ELMO domain containing 3","termid":"PBO:0046192"}


id: PBO:0060784
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B10 pseudogene 2","termid":"PBO:0060784"}


id: GO:1902281
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity.","definition_xrefs":["PMID:23721653","GOC:rb","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of RNA helicase activity (obsolete GO:1902281)","synonyms":[{"name":"down regulation of ATP-dependent RNA helicase activity","type":"exact"},{"name":"down-regulation of ATP-dependent RNA helicase activity","type":"exact"},{"name":"downregulation of ATP-dependent RNA helicase activity","type":"exact"},{"name":"inhibition of ATP-dependent RNA helicase activity","type":"narrow"},{"name":"negative regulation of ATP-dependent RNA helicase activity","type":"exact"}],"termid":"GO:1902281"}


id: PBO:0091807
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by S. japonicus rsv1","termid":"PBO:0091807"}


id: PBO:0082596
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Class I histone deacetylase (HDAC) family member; deacetylates Smc3p on lysine residues at anaphase onset; has sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; interacts with the Tup1p-Ssn6p corepressor complex","termid":"PBO:0082596"}


id: FYPO:0003586
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which replication fork processing is abnormal. Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted.","definition_xrefs":["GO:0031297","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal DNA replication","termid":"FYPO:0000217"},{"relation_name":"is_a","term_name":"DNA metabolism phenotype during vegetative growth","termid":"FYPO:0001346"},{"relation_name":"is_a","term_name":"abnormal cellular process during vegetative growth","termid":"FYPO:0001362"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0000293","FYPO:0000002"],"is_obsolete":false,"name":"abnormal replication fork processing","synonyms":[{"name":"abnormal HR-mediated fork restart","type":"related"},{"name":"abnormal collapsed replication fork processing","type":"exact"},{"name":"abnormal recovery from replication fork arrest","type":"exact"},{"name":"abnormal recovery from replication fork stalling","type":"exact"},{"name":"abnormal replication fork processing during mitotic cell cycle","type":"related"},{"name":"abnormal replication fork processing during vegetative growth","type":"exact"},{"name":"abnormal replication fork restart","type":"related"},{"name":"abnormal replication restart","type":"related"}],"termid":"FYPO:0003586"}


id: MONDO:0010303
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete colobomatous microphthalmia (obsolete MONDO:0010303)","termid":"MONDO:0010303","xrefs":{"Monarch":{"xref_id":"0010303"}}}


id: PBO:0090987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNARE Tlg2","termid":"PBO:0090987"}


id: GO:0070470
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.","definition_xrefs":["ISBN:0198547684","GOC:imk","GOC:mah","GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete plasma membrane respirasome (obsolete GO:0070470)","synonyms":[{"name":"plasma membrane electron transport chain","type":"exact"},{"name":"plasma membrane respiratory chain","type":"exact"}],"termid":"GO:0070470"}


id: MONDO:0044225
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete creatine kinase, brain type, ectopic expression of (obsolete MONDO:0044225)","secondary_identifiers":["HGNC:1992"],"synonyms":[{"name":"CKBE","type":"related"},{"name":"creatine KINASE, brain type, ectopic expression OF","type":"related"}],"termid":"MONDO:0044225","xrefs":{"Monarch":{"xref_id":"0044225"}}}


id: MONDO:1012969
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Hearing loss disorder that occurs in non-human animals","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing disorder, non-human animal","termid":"MONDO:1011318"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hearing loss disorder, non-human animal","termid":"MONDO:1012969","xrefs":{"Monarch":{"xref_id":"1012969"}}}


id: GO:0001325
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.","definition_xrefs":["PMID:12044938","GOC:jh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA metabolic process","termid":"GO:0006259"},{"relation_name":"is_a","term_name":"cellular component assembly","termid":"GO:0022607"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0044085","GO:0008150"],"is_obsolete":false,"name":"formation of extrachromosomal circular DNA","synonyms":[{"name":"assembly of extrachromosomal circular DNA","type":"exact"}],"termid":"GO:0001325"}


id: GO:2000941
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of plant-type cell wall cellulose catabolic process","termid":"GO:2000939"},{"relation_name":"is_a","term_name":"positive regulation of cell wall polysaccharide catabolic process","termid":"GO:2000968"},{"relation_name":"positively_regulates","term_name":"plant-type cell wall cellulose catabolic process","termid":"GO:0044348"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0005975"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"positive regulation of plant-type cell wall cellulose catabolic process","synonyms":[{"name":"positive regulation of plant-type cell wall polysaccharide breakdown","type":"exact"}],"termid":"GO:2000941"}


id: PBO:0051674
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"inhibitor of growth family member 4","termid":"PBO:0051674"}


id: GO:0010263
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.","definition_xrefs":["GOC:ct"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tricyclic triterpenoid metabolic process","termid":"GO:0010683"},{"relation_name":"is_a","term_name":"triterpenoid biosynthetic process","termid":"GO:0016104"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"tricyclic triterpenoid biosynthetic process","synonyms":[{"name":"tricyclic triterpenoid anabolism","type":"exact"},{"name":"tricyclic triterpenoid biosynthesis","type":"exact"},{"name":"tricyclic triterpenoid formation","type":"exact"},{"name":"tricyclic triterpenoid synthesis","type":"exact"}],"termid":"GO:0010263"}


id: MONDO:0016564
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"PSP-progressive non fluent aphasia (PSP-PNFA) is an atypical variant of progressive supranuclear palsy (PSP), a rare late-onset neurodegenerative disease. Unlike classic PSP (Richardson syndrome) patients present with an isolated speech production problem years before developing other motor features of PSP.","definition_xrefs":["Orphanet:240112"],"direct_ancestors":[{"relation_name":"is_a","term_name":"atypical progressive supranuclear palsy syndrome","termid":"MONDO:0020488"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"progressive supranuclear palsy-progressive non-fluent aphasia syndrome","secondary_identifiers":["UMLS:C5679850","MEDGEN:1842806","GARD:20649"],"synonyms":[{"name":"PSP-AOS","type":"exact"},{"name":"PSP-PNFA","type":"exact"},{"name":"progressive supranuclear palsy-apraxia of speech syndrome","type":"exact"}],"termid":"MONDO:0016564","xrefs":{"Monarch":{"xref_id":"0016564"}}}


id: GO:0045688
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of antipodal cell differentiation.","definition_xrefs":["GOC:go_curators","GOC:mtg_plant"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell differentiation","termid":"GO:0045595"},{"relation_name":"regulates","term_name":"antipodal cell differentiation","termid":"GO:0009557"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of antipodal cell differentiation","termid":"GO:0045688"}


id: FYPO:0001560
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased cellular amino acid level","termid":"FYPO:0003985"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"decreased cellular threonine level","secondary_identifiers":["FYPO:0001614"],"synonyms":[{"name":"decreased cellular L-threonine level","type":"exact"},{"name":"decreased cellular threonine level during mitotic cell cycle","type":"related"},{"name":"decreased cellular threonine level during vegetative growth","type":"exact"},{"name":"decreased level of threonine in cell","type":"exact"},{"name":"decreased threonine accumulation","type":"related"},{"name":"reduced cellular threonine level","type":"exact"},{"name":"reduced level of threonine in cell","type":"exact"}],"termid":"FYPO:0001560"}


id: GO:0072229
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proximal convoluted tubule development","termid":"GO:0072019"},{"relation_name":"is_a","term_name":"metanephric nephron tubule development","termid":"GO:0072234"},{"relation_name":"part_of","term_name":"metanephric proximal tubule development","termid":"GO:0072237"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric proximal convoluted tubule development","termid":"GO:0072229"}


id: MONDO:0006715
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Narrowing of the coronary artery lumen diameter.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"coronary artery disorder","termid":"MONDO:0005010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"coronary stenosis","secondary_identifiers":["DOID:4248","NANDO:2200246","SCTID:233970002","UMLS:C0242231","MedDRA:10011089","MESH:D023921","MEDGEN:66859"],"synonyms":[{"name":"coronary artery stenosis","type":"exact"}],"termid":"MONDO:0006715","xrefs":{"Monarch":{"xref_id":"0006715"}}}


id: PBO:0043951
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crystallin beta B2 pseudogene 1","termid":"PBO:0043951"}


id: GO:0050688
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to biotic stimulus","termid":"GO:0002831"},{"relation_name":"is_a","term_name":"regulation of defense response","termid":"GO:0031347"},{"relation_name":"is_a","term_name":"regulation of response to external stimulus","termid":"GO:0032101"},{"relation_name":"regulates","term_name":"defense response to virus","termid":"GO:0051607"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of defense response to virus","synonyms":[{"name":"regulation of antiviral response","type":"exact"}],"termid":"GO:0050688"}


id: MONDO:0042912
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schlegelberger-Grote syndrome","secondary_identifiers":["MESH:C536635","UMLS:C2931273","MEDGEN:419761"],"synonyms":[{"name":"Schlegelberger Grote syndrome","type":"related"},{"name":"syndrome with triphalangia of thumbs, thrombasthenia Glanzmann and deafness of internal ear","type":"related"},{"name":"triphalangeal thumbs thrombocytopathy deafness","type":"related"}],"termid":"MONDO:0042912","xrefs":{"Monarch":{"xref_id":"0042912"}}}


id: PBO:0027644
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_alpha-galactosidase_activity","termid":"PBO:0027644"}


id: SO:0002048
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A reading frame that could encode a full-length protein but which contains obvious mid-sequence disablements (frameshifts or premature stop codons).","definition_xrefs":["SGD:se"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reading_frame","termid":"SO:0000717"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"disabled_reading_frame","synonyms":[{"name":"dORF","type":"exact"},{"name":"disabled ORF","type":"exact"},{"name":"disabled_reading frame","type":"related"}],"termid":"SO:0002048"}


id: GO:1905271
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.","definition_xrefs":["GOC:als","PMID:21106936","GOC:TermGenie","GO_REF:0000059"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of proton-transporting ATP synthase activity, rotational mechanism (obsolete GO:1905271)","synonyms":[{"name":"regulation of H+-transporting ATP synthase activity","type":"exact"},{"name":"regulation of hydrogen ion translocating F-type ATPase activity","type":"exact"},{"name":"regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism","type":"exact"},{"name":"regulation of hydrogen ion transporting two-sector ATPase activity","type":"exact"}],"termid":"GO:1905271"}


id: GO:1990453
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex.","definition_xrefs":["PMID:24843044","GOC:bhm"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear protein-containing complex","termid":"GO:0140513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0005634"],"is_obsolete":false,"name":"nucleosome disassembly/reassembly complex","synonyms":[{"name":"eaf5/7/3 complex","type":"narrow"}],"termid":"GO:1990453"}


id: GO:0032133
data:
  {"annotated_genes":["SJAG_04412","SJAG_01837","SJAG_00697","SJAG_02807"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[73669,77394,109578,112267],"is_not":false,"summary":null,"term":"GO:0032133"}]},"cv_name":"cellular_component","definition":"A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.","definition_xrefs":["PMID:19570910","PMID:16824200","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule associated complex","termid":"GO:0005875"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00697":null,"SJAG_01837":null,"SJAG_02807":null,"SJAG_04412":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0015630"}],"interesting_parent_ids":["GO:0032991","GO:0015630","GO:0005575"],"is_obsolete":false,"name":"chromosome passenger complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"CPC","type":"broad"},{"name":"CPC complex","type":"exact"},{"name":"chromosomal passenger complex","type":"exact"}],"termid":"GO:0032133","terms_by_termid":{"GO:0032133":null}}


id: PBO:0085541
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein component of the small (40S) ribosomal subunit; interacts with Kti11p; deletion causes hypersensitivity to zymocin; homologous to mammalian ribosomal protein S7, no bacterial homolog; RPS7A has a paralog, RPS7B, that arose from the whole genome duplication","termid":"PBO:0085541"}


id: GO:1900856
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of fumitremorgin B biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of fumitremorgin B biosynthetic process (obsolete GO:1900856)","synonyms":[{"name":"down regulation of fumitremorgin B biosynthetic process","type":"exact"},{"name":"down-regulation of fumitremorgin B biosynthetic process","type":"exact"},{"name":"downregulation of fumitremorgin B biosynthetic process","type":"exact"}],"termid":"GO:1900856"}


id: PBO:0116781
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ventricular heart development associated lncRNA","termid":"PBO:0116781"}


id: GO:0009075
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete histidine family amino acid metabolic process (obsolete GO:0009075)","synonyms":[{"name":"histidine family amino acid metabolic process","type":"exact"},{"name":"histidine family amino acid metabolism","type":"exact"}],"termid":"GO:0009075"}


id: PBO:0076504
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taste 2 receptor member 4","termid":"PBO:0076504"}


id: MONDO:0019001
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete biotin-responsive basal ganglia disease (obsolete MONDO:0019001)","termid":"MONDO:0019001","xrefs":{"Monarch":{"xref_id":"0019001"}}}


id: PBO:0080375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vacuolar protein sorting 4 homolog B","termid":"PBO:0080375"}


id: GO:0005319
data:
  {"annotated_genes":["SJAG_02375","SJAG_00669","SJAG_02323","SJAG_04984","SJAG_00576","SJAG_00018","SJAG_05209","SJAG_01731","SJAG_03851","SJAG_00230","SJAG_03076","SJAG_02897","SJAG_01095","SJAG_02957","SJAG_03774","SJAG_03741","SJAG_00589","SJAG_02114","SJAG_02132","SJAG_16459","SJAG_04370","SJAG_02581","SJAG_02516","SJAG_03338","SJAG_01722","SJAG_01470","SJAG_01305","SJAG_03746","SJAG_06440","SJAG_00355","SJAG_01590","SJAG_03416","SJAG_03710","SJAG_01229","SJAG_01329","SJAG_03247","SJAG_03100","SJAG_00587","SJAG_03050","SJAG_02943","SJAG_03172","SJAG_01945","SJAG_03721","SJAG_01225","SJAG_03718"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[105439,102677],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015247"},{"annotations":[90866,90860,90863,90865,90861,90864,90867,90862,90868],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140326"},{"annotations":[112942],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034202"},{"annotations":[98260,94760],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140351"},{"annotations":[100582],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0170045"},{"annotations":[109024],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120013"},{"annotations":[99810],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0180013"},{"annotations":[101623,102555,70575],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990050"},{"annotations":[94762,98262],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140345"},{"annotations":[100535,94763,98263],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090554"},{"annotations":[97888],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120019"},{"annotations":[94764,98264,99812],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090555"},{"annotations":[70446,76936,76653,74887,73611],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008526"},{"annotations":[112883,99813],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140346"},{"annotations":[99814,98265,94765,112884],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090556"},{"annotations":[73556,103935,101759],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017128"},{"annotations":[91234,104389,106211,107110,107889,89555,108014],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120014"},{"annotations":[108576,94579,116612,102956,111709,77301,91812,109736],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120015"}]},"cv_name":"molecular_function","definition":"Enables the directed movement of lipids into, out of or within a cell, or between cells.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transporter activity","termid":"GO:0005215"}],"gene_count":45,"genes_by_uniquename":{"SJAG_00018":null,"SJAG_00230":null,"SJAG_00355":null,"SJAG_00576":null,"SJAG_00587":null,"SJAG_00589":null,"SJAG_00669":null,"SJAG_01095":null,"SJAG_01225":null,"SJAG_01229":null,"SJAG_01305":null,"SJAG_01329":null,"SJAG_01470":null,"SJAG_01590":null,"SJAG_01722":null,"SJAG_01731":null,"SJAG_01945":null,"SJAG_02114":null,"SJAG_02132":null,"SJAG_02323":null,"SJAG_02375":null,"SJAG_02516":null,"SJAG_02581":null,"SJAG_02897":null,"SJAG_02943":null,"SJAG_02957":null,"SJAG_03050":null,"SJAG_03076":null,"SJAG_03100":null,"SJAG_03172":null,"SJAG_03247":null,"SJAG_03338":null,"SJAG_03416":null,"SJAG_03710":null,"SJAG_03718":null,"SJAG_03721":null,"SJAG_03741":null,"SJAG_03746":null,"SJAG_03774":null,"SJAG_03851":null,"SJAG_04370":null,"SJAG_04984":null,"SJAG_05209":null,"SJAG_06440":null,"SJAG_16459":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215"],"is_obsolete":false,"name":"lipid transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-5683672","Reactome:R-HSA-8866329","Reactome:R-HSA-6801250","Reactome:R-HSA-5683714","Reactome:R-HSA-8848053","Reactome:R-HSA-1369052","Reactome:R-HSA-5682285","Reactome:R-HSA-5688397","Reactome:R-HSA-5682311","Reactome:R-HSA-1369028","Reactome:R-HSA-174786"],"synonyms":[{"name":"apolipoprotein","type":"related"},{"name":"lipophorin","type":"narrow"}],"termid":"GO:0005319","terms_by_termid":{"GO:0008526":null,"GO:0015247":null,"GO:0017128":null,"GO:0034202":null,"GO:0090554":null,"GO:0090555":null,"GO:0090556":null,"GO:0120013":null,"GO:0120014":null,"GO:0120015":null,"GO:0120019":null,"GO:0140326":null,"GO:0140345":null,"GO:0140346":null,"GO:0140351":null,"GO:0170045":null,"GO:0180013":null,"GO:1990050":null}}


id: GO:1904437
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of transferrin receptor binding.","definition_xrefs":["PMID:18353247","GOC:kom","GOC:TermGenie","GO_REF:0000059","GOC:BHF"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of transferrin receptor binding (obsolete GO:1904437)","synonyms":[{"name":"activation of transferrin receptor binding","type":"narrow"},{"name":"up regulation of transferrin receptor binding","type":"exact"},{"name":"up-regulation of transferrin receptor binding","type":"exact"},{"name":"upregulation of transferrin receptor binding","type":"exact"}],"termid":"GO:1904437"}


id: MONDO:0037251
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A chronic congestive enlargement of the spleen leading to the destruction of blood cells resulting in pancytopenia.","definition_xrefs":["PMID:35800794"],"direct_ancestors":[{"relation_name":"is_a","term_name":"splenic disorder","termid":"MONDO:0002332"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"congestive splenomegaly","secondary_identifiers":["GARD:5888","UMLS:C0154307","MESH:C537903","SCTID:19058002","MEDGEN:56339"],"synonyms":[{"name":"Banti syndrome","type":"exact"},{"name":"Banti's disease","type":"exact"},{"name":"Banti's spleen","type":"exact"},{"name":"Banti's syndrome","type":"exact"},{"name":"fibrocongestive splenomegaly","type":"related"},{"name":"idiopathic congestive splenomegaly","type":"related"},{"name":"idiopathic portal hypertension","type":"related"}],"termid":"MONDO:0037251","xrefs":{"Monarch":{"xref_id":"0037251"}}}


id: MONDO:1011176
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Osteochondrosis that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondrosis, non-human animal","termid":"MONDO:1010299"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteochondrosis, cattle","secondary_identifiers":["OMIA:000750-9913"],"termid":"MONDO:1011176","xrefs":{"Monarch":{"xref_id":"1011176"}}}


id: PR:Q9Y806
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC146.04 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9Y806"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FAD-linked sulfhydryl oxidase erv2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC146.04","synonyms":[{"name":"Spom972h-SPBC146.04","type":"exact"}],"termid":"PR:Q9Y806"}


id: MONDO:1010750
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Epidermolysis bullosa that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epidermolysis bullosa, non-human animal","termid":"MONDO:1010129"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"epidermolysis bullosa, dog","secondary_identifiers":["OMIA:000340-9615"],"termid":"MONDO:1010750","xrefs":{"Monarch":{"xref_id":"1010750"}}}


id: PBO:0046684
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation termination factor 1 pseudogene 2","termid":"PBO:0046684"}


id: PBO:0076810
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TENM3 antisense transcript 1","termid":"PBO:0076810"}


id: GO:1904402
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.","definition_xrefs":["PMID:17822405","GO_REF:0000071","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to ketone","termid":"GO:1901654"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to nocodazole","termid":"GO:1904402"}


id: FYPO:0003611
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of protein measured in a cell during one or both meiotic nuclear divisions is higher than normal. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein level","termid":"FYPO:0000836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0006551","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"increased protein level during meiosis","synonyms":[{"name":"increased protein accumulation during meiosis","type":"related"},{"name":"increased protein level during meiotic nuclear division","type":"exact"}],"termid":"FYPO:0003611"}


id: MONDO:0033056
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete genetic facial cleft (obsolete MONDO:0033056)","secondary_identifiers":["Orphanet:414726"],"termid":"MONDO:0033056","xrefs":{"Monarch":{"xref_id":"0033056"}}}


id: GO:0015786
data:
  {"annotated_genes":["SJAG_04406","SJAG_04162"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75479],"is_not":false,"summary":null,"term":"GO:0015786"},{"annotations":[112756],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120112"}]},"cv_name":"biological_process","definition":"The process in which UDP-glucose is transported across a membrane.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic anion transport","termid":"GO:0015711"},{"relation_name":"is_a","term_name":"pyrimidine nucleotide-sugar transmembrane transport","termid":"GO:0090481"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04162":null,"SJAG_04406":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055085","GO:0051179","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"UDP-glucose transmembrane transport","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0015786","terms_by_termid":{"GO:0015786":null,"GO:0120112":null}}


id: PBO:0113243
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Nuclear peptidyl-prolyl cis-trans isomerase (PPIase); impacts expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; role in rDNA maintenance; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers","termid":"PBO:0113243"}


id: GO:0010849
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of proton transport","termid":"GO:0010155"},{"relation_name":"is_a","term_name":"regulation of monoatomic ion transmembrane transporter activity","termid":"GO:0032412"},{"relation_name":"is_a","term_name":"regulation of ATP-dependent activity","termid":"GO:0043462"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of proton-transporting ATPase activity, rotational mechanism","synonyms":[{"name":"regulation of V-type ATPase activity","type":"broad"},{"name":"regulation of hydrogen ion transporting ATPase activity, rotational mechanism","type":"exact"}],"termid":"GO:0010849"}


id: FYPO:0005360
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the RTS1 replication termination site prevents replication fork movement in the opposite of normal direction. Normally, RTS1 acts as a barrier to replication forks moving in the cenII-distal direction.","definition_xrefs":["PomBase:mah","PMID:18723894"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal replication fork arrest at mating-type locus","termid":"FYPO:0003083"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0005447","FYPO:0000293","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"reversed RTS1 barrier polarity","synonyms":[{"name":"reversed RTS1 barrier polarity during mitotic cell cycle","type":"related"},{"name":"reversed RTS1 barrier polarity during vegetative growth","type":"exact"}],"termid":"FYPO:0005360"}


id: PBO:0086317
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with similarity to cyclin-dependent kinase inhibitors; downregulates low-affinity phosphate transport during phosphate limitation by targeting Pho87p to the vacuole; upstream region harbors putative hypoxia response element (HRE) cluster; overproduction suppresses a plc1 null mutation; promoter shows an increase in Snf2p occupancy after heat shock; GFP-fusion protein localizes to the cytoplasm","termid":"PBO:0086317"}


id: MONDO:0019591
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Insufficient production of all the anterior pituitary hormones.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"combined pituitary hormone deficiencies, genetic form","termid":"MONDO:0013099"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"panhypopituitarism","secondary_identifiers":["GARD:15020","Orphanet:90695","SCTID:32390006","DOID:9410","NCIT:C110940","UMLS:C0242343","MEDGEN:69171","ICD9:253.2","icd11.foundation:1576287890","MedDRA:10033662"],"synonyms":[{"name":"Simmond's disease","type":"exact"},{"name":"Simmonds' disease","type":"exact"},{"name":"complete hypopituitarism","type":"exact"}],"termid":"MONDO:0019591","xrefs":{"Monarch":{"xref_id":"0019591"}}}


id: PBO:0058966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"makorin ring finger protein 9, pseudogene","termid":"PBO:0058966"}


id: MONDO:0008733
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Familial glucocorticoid deficiency (FGD) is a group of primary adrenal insufficiencies characterized clinically by neonatal hyperpigmentation, hypoglycemia, failure to thrive, and recurrent infections, and biochemically by glucocorticoid deficiency without mineralocorticoid deficiency.","definition_xrefs":["Orphanet:361"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"chronic primary adrenal insufficiency","termid":"MONDO:0015129"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"familial glucocorticoid deficiency","secondary_identifiers":["MESH:C565974","SCTID:765326001","NCIT:C120446","DOID:0080620","icd11.foundation:861297039","GARD:2498","MEDGEN:885955","OMIMPS:202200","UMLS:C4054695"],"synonyms":[{"name":"GCCD","type":"related"},{"name":"glucocorticoid deficiency","type":"broad"}],"termid":"MONDO:0008733","xrefs":{"Monarch":{"xref_id":"0008733"}}}


id: MONDO:0024560
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"patent ductus arteriosus","termid":"MONDO:0011827"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"PDA1","secondary_identifiers":["GARD:7342","OMIM:607411","UMLS:C4282128","MEDGEN:924232"],"synonyms":[{"name":"PDA","type":"related"},{"name":"PDA1","type":"exact"},{"name":"patent ductus arteriosus 1","type":"related"},{"name":"patent ductus arteriosus, susceptibility to","type":"exact"}],"termid":"MONDO:0024560","xrefs":{"Monarch":{"xref_id":"0024560"}}}


id: PBO:0077775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOMM40 pseudogene 2","termid":"PBO:0077775"}


id: PBO:0073211
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"semaphorin 4C","termid":"PBO:0073211"}


id: PBO:0069927
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1219, pseudogene","termid":"PBO:0069927"}


id: GO:0047464
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (heparosan-N-sulfate)(n) = (heparan-N-sulfate)(n). Converts D-glucosyluronate residues to L-iduronate residues.","definition_xrefs":["EC:5.1.3.17","MetaCyc:5.1.3.17-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"racemase and epimerase activity, acting on carbohydrates and derivatives","termid":"GO:0016857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016853"],"is_obsolete":false,"name":"heparosan-N-sulfate-glucuronate 5-epimerase activity","secondary_identifiers":["Reactome:R-HSA-2076371","RHEA:20197","Reactome:R-HSA-2024100"],"synonyms":[{"name":"C-5 uronosyl epimerase activity","type":"related"},{"name":"D-glucuronyl C-5 epimerase activity","type":"related"},{"name":"heparosan epimerase activity","type":"related"},{"name":"heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity","type":"related"},{"name":"heparosan-N-sulphate-glucuronate 5-epimerase activity","type":"exact"},{"name":"poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity","type":"related"},{"name":"polyglucuronate epimerase activity","type":"related"}],"termid":"GO:0047464"}


id: MONDO:0004929
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"disease of orbital part of eye adnexa","termid":"MONDO:0004751"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"constant exophthalmos","secondary_identifiers":["SCTID:89907009","MEDGEN:509884","DOID:9945","icd11.foundation:2100094996","ICD9:376.31","UMLS:C0155267"],"termid":"MONDO:0004929","xrefs":{"Monarch":{"xref_id":"0004929"}}}


id: PBO:0030105
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cellular_glutamate_level","termid":"PBO:0030105"}


id: PBO:0045081
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DLGAP5 pseudogene 2","termid":"PBO:0045081"}


id: GO:0035847
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.","definition_xrefs":["GOC:bf","GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oviduct epithelium development","termid":"GO:0035846"},{"relation_name":"part_of","term_name":"uterus development","termid":"GO:0060065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"uterine epithelium development","synonyms":[{"name":"uterus epithelial development","type":"exact"}],"termid":"GO:0035847"}


id: PBO:0030129
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cellular_magnesium_level","termid":"PBO:0030129"}


id: GO:0001302
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.","definition_xrefs":["GOC:jh","PMID:12044934"],"gene_count":0,"genotype_count":0,"name":"obsolete replicative cell aging (obsolete GO:0001302)","synonyms":[{"name":"replicative cell ageing","type":"exact"}],"termid":"GO:0001302"}


id: GO:1990578
data:
  {"annotated_genes":["SJAG_04583","SJAG_01785","SJAG_01422","SJAG_01227","SJAG_03281","SJAG_01329","SJAG_00784"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[87695,95051,98133,98986,100940,106690,115992],"is_not":false,"summary":null,"term":"GO:1990578"}]},"cv_name":"cellular_component","definition":"The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.","definition_xrefs":["PMID:25454947"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle membrane","termid":"GO:0031090"},{"relation_name":"part_of","term_name":"endoplasmic reticulum membrane","termid":"GO:0005789"},{"relation_name":"part_of","term_name":"perinuclear endoplasmic reticulum","termid":"GO:0097038"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00784":null,"SJAG_01227":null,"SJAG_01329":null,"SJAG_01422":null,"SJAG_01785":null,"SJAG_03281":null,"SJAG_04583":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"part_of","termid":"GO:0005789"},{"rel_name":"part_of","termid":"GO:0005783"}],"interesting_parent_ids":["GO:0005789","GO:0005783","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"perinuclear endoplasmic reticulum membrane","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"perinuclear ER membrane","type":"exact"}],"termid":"GO:1990578","terms_by_termid":{"GO:1990578":null}}


id: GO:0006967
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of antifungal peptide production","termid":"GO:0002804"},{"relation_name":"is_a","term_name":"positive regulation of antimicrobial peptide biosynthetic process","termid":"GO:0002807"},{"relation_name":"is_a","term_name":"regulation of antifungal peptide biosynthetic process","termid":"GO:0002810"},{"relation_name":"positively_regulates","term_name":"antifungal peptide biosynthetic process","termid":"GO:0002783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of antifungal peptide biosynthetic process","synonyms":[{"name":"activation of antifungal peptide biosynthetic process","type":"narrow"},{"name":"antifungal peptide induction","type":"exact"},{"name":"antifungal polypeptide induction","type":"exact"},{"name":"stimulation of antifungal peptide biosynthetic process","type":"narrow"},{"name":"up regulation of antifungal peptide biosynthetic process","type":"exact"},{"name":"up-regulation of antifungal peptide biosynthetic process","type":"exact"},{"name":"upregulation of antifungal peptide biosynthetic process","type":"exact"}],"termid":"GO:0006967"}


id: SO:0000061
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A binding site that, in the nucleotide molecule, interacts selectively and non-covalently with polypeptide residues of a restriction enzyme.","definition_xrefs":["SO:cb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclease_binding_site","termid":"SO:0000059"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"restriction_enzyme_binding_site","synonyms":[{"name":"restriction endonuclease binding site","type":"exact"},{"name":"restriction enzyme binding site","type":"exact"}],"termid":"SO:0000061"}


id: PR:G2TRT6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC417.16 gene.","definition_xrefs":["PRO:DNx","UniProtKB:G2TRT6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC417.16","synonyms":[{"name":"Spom972h-SPCC417.16","type":"exact"}],"termid":"PR:G2TRT6"}


id: GO:0003385
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.","definition_xrefs":["GOC:dph","GOC:tb","GOC:ascb_2009"],"gene_count":0,"genotype_count":0,"name":"obsolete cell-cell signaling involved in amphid sensory organ development (obsolete GO:0003385)","synonyms":[{"name":"cell-cell signalling involved in amphid sensory organ development","type":"exact"}],"termid":"GO:0003385"}


id: MONDO:0019970
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Sinding-Larsen-Johansson disease is a type of osteochondrosis affecting the attachment of the patellar tendon to the patella and characterized by tenderness and localized swelling of the patella.","definition_xrefs":["Orphanet:97337"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteochondrosis","termid":"MONDO:0018381"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Sinding-Larsen-Johansson disease","secondary_identifiers":["icd11.foundation:1733785551","MedDRA:10063585","UMLS:C1504517","MEDGEN:1672493","GARD:19366"],"synonyms":[{"name":"Osteochondrosis of patella","type":"exact"},{"name":"aseptic necrosis of patella","type":"exact"}],"termid":"MONDO:0019970","xrefs":{"Monarch":{"xref_id":"0019970"}}}


id: GO:0015112
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inorganic anion transmembrane transporter activity","termid":"GO:0015103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"nitrate transmembrane transporter activity","synonyms":[{"name":"nitrite/nitrate porter activity","type":"related"}],"termid":"GO:0015112"}


id: GO:0140892
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction chloride(in) + 2 hydrogencarbonate(out) + Na+(out) = chloride(out) + 2 hydrogencarbonate(in) + Na+(in).","definition_xrefs":["PMID:20389022","PMID:18577713","PMID:8189393"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium ion transmembrane transporter activity","termid":"GO:0015081"},{"relation_name":"is_a","term_name":"metal cation:monoatomic cation antiporter activity","termid":"GO:0140828"},{"relation_name":"is_a","term_name":"chloride:bicarbonate antiporter activity","termid":"GO:0140900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"sodium,bicarbonate:chloride antiporter activity","secondary_identifiers":["TC:2.A.31.2.4"],"synonyms":[{"name":"sodium,hydrogencarbonate:chloride antiporter activity","type":"exact"},{"name":"sodium-dependent chloride/bicarbonate exchanger activity","type":"exact"}],"termid":"GO:0140892"}


id: GO:0061977
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.","definition_xrefs":["PMID:20097540"],"direct_ancestors":[{"relation_name":"is_a","term_name":"articular cartilage development","termid":"GO:0061975"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hip joint articular cartilage development","termid":"GO:0061977"}


id: PBO:0088971
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase II CTD phosphatase Fcp1","termid":"PBO:0088971"}


id: PBO:0088741
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein trafficking protein Pga2","termid":"PBO:0088741"}


id: SO:0100015
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The more polar, carboxy-terminal region of the signal peptide (approx 3-7 aa).","definition_xrefs":["EBIBS:GAR"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cleaved_peptide_region","termid":"SO:0100011"},{"relation_name":"part_of","term_name":"signal_peptide","termid":"SO:0000418"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"c_terminal_region","synonyms":[{"name":"C-region","type":"related"}],"termid":"SO:0100015"}


id: PBO:0026695
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_tellurite","termid":"PBO:0026695"}


id: MONDO:0100209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"X inactivation, familial skewed","termid":"MONDO:0100209","xrefs":{"Monarch":{"xref_id":"0100209"}}}


id: GO:0044659
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm.","definition_xrefs":["PMID:26728778","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated cytolysis of host cell","termid":"GO:0001897"},{"relation_name":"is_a","term_name":"viral release from host cell","termid":"GO:0019076"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"viral release from host cell by cytolysis","secondary_identifiers":["VZ:1077","GO:0019077","GO:0046756"],"synonyms":[{"name":"cytolysis by virus of host cell","type":"related"},{"name":"lytic viral life cycle","type":"related"},{"name":"lytic viral release","type":"exact"},{"name":"viral exit from host cell by cytolysis","type":"exact"},{"name":"viral release by cell lysis","type":"exact"},{"name":"viral release by host cell lysis","type":"exact"}],"termid":"GO:0044659"}


id: GO:0140667
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of production of oxytocin.","definition_xrefs":["PMID:25096581"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of gene expression","termid":"GO:0010468"},{"relation_name":"regulates","term_name":"oxytocin production","termid":"GO:0036162"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of oxytocin production","termid":"GO:0140667"}


id: GO:0100039
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates pyrimidine nucleotide biosynthetic process.","definition_xrefs":["GOC:cjm","GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter (obsolete GO:0100039)","termid":"GO:0100039"}


id: PBO:0028244
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_SRP-dependent_cotranslational_protein_targeting_to_membrane","termid":"PBO:0028244"}


id: PBO:0081119
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZNFX1 antisense RNA 1","termid":"PBO:0081119"}


id: PBO:0084469
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase","termid":"PBO:0084469"}


id: PBO:0000146
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ThiJ domain protein","termid":"PBO:0000146"}


id: PATO:0000999
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A quality of a single process inhering in a bearer by virtue of the bearer's successive change from one thing or state to another and back again.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"occurrence","termid":"PATO:0000057"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alternation","termid":"PATO:0000999"}


id: GO:0010663
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.","definition_xrefs":["GOC:tb","GOC:mtg_apoptosis","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of muscle cell apoptotic process","termid":"GO:0010661"},{"relation_name":"is_a","term_name":"regulation of striated muscle cell apoptotic process","termid":"GO:0010662"},{"relation_name":"positively_regulates","term_name":"striated muscle cell apoptotic process","termid":"GO:0010658"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of striated muscle cell apoptotic process","synonyms":[{"name":"positive regulation of striated muscle cell apoptosis","type":"narrow"}],"termid":"GO:0010663"}


id: GO:0061936
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.","definition_xrefs":["PMID:21123745"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular process involved in reproduction in multicellular organism","termid":"GO:0022412"},{"relation_name":"is_a","term_name":"plasma membrane fusion","termid":"GO:0045026"},{"relation_name":"part_of","term_name":"double fertilization forming a zygote and endosperm","termid":"GO:0009567"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0061024"],"is_obsolete":false,"name":"fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm","termid":"GO:0061936"}


id: MONDO:0004146
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A WHO grade I meningioma characterized by the coexistence of meningothelial cells and fibrous architectural patterns.","definition_xrefs":["NCIT:C4333"],"direct_ancestors":[{"relation_name":"is_a","term_name":"meningioma","termid":"MONDO:0016642"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transitional meningioma","secondary_identifiers":["UMLS:C0334611","MEDGEN:83174","ICDO:9537/0","DOID:7213"],"synonyms":[{"name":"mixed meningioma","type":"exact"},{"name":"transitional (mixed) meningioma","type":"exact"},{"name":"transitional meningioma (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0004146","xrefs":{"Monarch":{"xref_id":"0004146"}}}


id: GO:0010645
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.","definition_xrefs":["GOC:tb","GOC:dph","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cell communication","termid":"GO:0010646"},{"relation_name":"regulates","term_name":"cell communication by chemical coupling","termid":"GO:0010643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cell communication by chemical coupling","termid":"GO:0010645"}


id: MONDO:0013953
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any primary immunodeficiency disease in which the cause of the disease is a mutation in the IFNGR2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn error of immunity","termid":"MONDO:0003778"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 28","secondary_identifiers":["MEDGEN:862384","UMLS:C4013947","DOID:0111995","OMIM:614889"],"synonyms":[{"name":"IFNGR2 primary immunodeficiency disease","type":"exact"},{"name":"IMD28","type":"related"},{"name":"Ifngr2 deficiency","type":"related"},{"name":"immunodeficiency 28","type":"exact"},{"name":"immunodeficiency 28, Mycobacteriosis","type":"related"},{"name":"immunodeficiency type 28","type":"exact"},{"name":"primary immunodeficiency disease caused by mutation in IFNGR2","type":"exact"}],"termid":"MONDO:0013953","xrefs":{"Monarch":{"xref_id":"0013953"}}}


id: MOD:01764
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an N'-hydrogen atom of a histidine residue with the Proteome Sciences TMT6plex-131 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-histidine residue","termid":"MOD:00909"},{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent N-acylated residue","termid":"MOD:01717"},{"relation_name":"is_a","term_name":"TMT6plex-131 reporter+balance reagent acylated residue","termid":"MOD:01760"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-131 reporter+balance reagent N'-acylated histidine","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01764"}


id: GO:0061365
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the activity of triglyceride lipase.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of lipase activity","termid":"GO:0060193"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of triglyceride lipase activity","synonyms":[{"name":"positive regulation of TAG activity","type":"exact"}],"termid":"GO:0061365"}


id: PR:Q9UTQ9
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- spc2 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UTQ9"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"signal peptidase complex subunit spc2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1071.04c","synonyms":[{"name":"Spom972h-spc2","type":"exact"},{"name":"microsomal signal peptidase subunit 2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UTQ9"}


id: PBO:0109400
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed transcript, Y-linked 27, pseudogene","termid":"PBO:0109400"}


id: PBO:0060043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND4 pseudogene 31","termid":"PBO:0060043"}


id: GO:0007505
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body.","definition_xrefs":["GOC:bf","ISBN:0879694238"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fat body development","termid":"GO:0007503"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"adult fat body development","termid":"GO:0007505"}


id: PBO:0063441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphodiesterase 6C","termid":"PBO:0063441"}


id: PBO:0034238
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-correlated_with_condition","termid":"PBO:0034238"}


id: MONDO:0958229
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"vascular disorder","termid":"MONDO:0005385"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bleeding disorder, vascular-type","secondary_identifiers":["UMLS:C5935577","MEDGEN:1853829","OMIM:620715"],"termid":"MONDO:0958229","xrefs":{"Monarch":{"xref_id":"0958229"}}}


id: MONDO:0044971
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete disease of macromolecular complex (obsolete MONDO:0044971)","termid":"MONDO:0044971","xrefs":{"Monarch":{"xref_id":"0044971"}}}


id: PATO:0001021
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A physical quality inhering in a bearer by virtue of the bearer's capacity to do work.","definition_xrefs":["Wikipedia:http://en.wikipedia.org/wiki/Energy"],"direct_ancestors":[{"relation_name":"is_a","term_name":"physical quality","termid":"PATO:0001018"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"energy","termid":"PATO:0001021"}


id: PBO:0049077
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein-coupled receptor 108","termid":"PBO:0049077"}


id: GO:0051955
data:
  {"annotated_genes":["SJAG_02605","SJAG_00991","SJAG_05346","SJAG_03591","SJAG_03970"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88410],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905533"},{"annotations":[110913,92071,99210,93659],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905589"},{"annotations":[92072,93660,99211],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905534"},{"annotations":[93661],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905626"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amine transport","termid":"GO:0051952"},{"relation_name":"regulates","term_name":"amino acid transport","termid":"GO:0006865"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00991":null,"SJAG_02605":null,"SJAG_03591":null,"SJAG_03970":null,"SJAG_05346":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of amino acid transport","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0051955","terms_by_termid":{"GO:1905533":null,"GO:1905534":null,"GO:1905589":null,"GO:1905626":null}}


id: GO:0003792
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id: GO:0043063
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id: MONDO:0018239
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id: MOD:00787
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id: MONDO:0010893
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id: MONDO:0016808
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id: PBO:0054232
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id: FYPO:0003630
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id: PBO:0011088
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id: PBO:0030314
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id: MONDO:0027407
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id: GO:0055086
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id: GO:0070686
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  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The portion of the plasma membrane surrounding a macropinocytic cup.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell projection membrane","termid":"GO:0031253"},{"relation_name":"part_of","term_name":"macropinocytic cup","termid":"GO:0070685"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005886"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0005886"],"is_obsolete":false,"name":"macropinocytic cup membrane","synonyms":[{"name":"crown membrane","type":"exact"}],"termid":"GO:0070686"}


id: PBO:0044440
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome P450 family 4 subfamily F member 9, pseudogene","termid":"PBO:0044440"}


id: MONDO:0010565
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Protanopia is a severe type of color vision deficiency caused by the complete absence of red retinal photoreceptors. Protans have difficulties distinguishing between blue and green colors and also between red and green colors. It is a form of dichromatism in which the subject can only perceive light wavelengths from 400 to 650 nm, instead of the usual 700 nm. Pure reds cannot be seen, instead appearing black; purple colors cannot be distinguished from blues; more orange-tinted reds may appear as very dim yellows, and all orange-yellow-green shades of too long a wavelength to stimulate the blue receptors appear as a similar yellow hue. It is hereditary, sex-linked, and present in 1% of males.","definition_xrefs":["EFO:0005580"],"direct_ancestors":[{"relation_name":"is_a","term_name":"color vision disorder","termid":"MONDO:0001703"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"hereditary neurological disease","termid":"MONDO:0100545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"red color blindness","secondary_identifiers":["SCTID:51445007","ICD9:368.51","UMLS:C0155015","Orphanet:319691","DOID:13910","OMIM:303900","ICD10CM:H53.54","MEDGEN:56350"],"synonyms":[{"name":"CBP","type":"related"},{"name":"colorblindness, partial, protan series","type":"related"},{"name":"colorblindness, protan","type":"exact"},{"name":"partial achromatopsia, protan type","type":"exact"},{"name":"protan defect","type":"exact"},{"name":"protanomaly","type":"related"},{"name":"protanopia","type":"exact"},{"name":"red color blindness","type":"exact"},{"name":"red colorblindness","type":"related"}],"termid":"MONDO:0010565","xrefs":{"Monarch":{"xref_id":"0010565"}}}


id: MONDO:1011060
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Polycystic kidney disease that occurs in sheep.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polycystic kidney disease, non-human animal","termid":"MONDO:1010262"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"polycystic kidney disease, sheep","secondary_identifiers":["OMIA:000807-9940"],"termid":"MONDO:1011060","xrefs":{"Monarch":{"xref_id":"1011060"}}}


id: GO:0021944
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.","definition_xrefs":["GOC:dgh","GOC:dph","GOC:jid","PMID:15157725","GO_REF:0000021","GOC:cls"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell adhesion","termid":"GO:0098609"},{"relation_name":"part_of","term_name":"hindbrain radial glia guided cell migration","termid":"GO:0021932"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0007155"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration","termid":"GO:0021944"}


id: GO:0075528
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process in which a virus effects a change in the host immune response.","definition_xrefs":["GOC:bf","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete perturbation by virus of host immune response (obsolete GO:0075528)","synonyms":[{"name":"regulation by virus of host immune system process","type":"exact"}],"termid":"GO:0075528"}


id: FYPO:0005666
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  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal during one or both meiotic nuclear divisions.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin cytoskeleton","termid":"FYPO:0005665"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0004803"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0004803"],"is_obsolete":false,"name":"abnormal actin cytoskeleton during meiosis","synonyms":[{"name":"abnormal actin cytoskeleton during meiotic nuclear division","type":"exact"},{"name":"abnormal actin cytoskeleton physical object quality during meiosis","type":"exact"}],"termid":"FYPO:0005666"}


id: MOD:01046
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  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-tyrosine residue to 3'-chloro-L-tyrosine.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monochlorinated L-tyrosine","termid":"MOD:01028"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3'-chloro-L-tyrosine","synonyms":[{"name":"3'-ClTyr","type":"exact"}],"termid":"MOD:01046"}


id: PBO:0072734
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sphingosine-1-phosphate receptor 4","termid":"PBO:0072734"}


id: MOD:02059
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  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that contains an L-valine residue crosslinked to one or more amino acid residues.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-valine residue","termid":"MOD:00920"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crosslinked L-valine residue","synonyms":[{"name":"XlnkVal","type":"exact"}],"termid":"MOD:02059"}


id: GO:0032733
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  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cytokine production","termid":"GO:0001819"},{"relation_name":"is_a","term_name":"regulation of interleukin-10 production","termid":"GO:0032653"},{"relation_name":"positively_regulates","term_name":"interleukin-10 production","termid":"GO:0032613"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of interleukin-10 production","secondary_identifiers":["GO:2001181","GO:0045082"],"synonyms":[{"name":"activation of interleukin-10 production","type":"narrow"},{"name":"positive regulation of IL-10 production","type":"exact"},{"name":"positive regulation of interleukin-10 biosynthetic process","type":"narrow"},{"name":"positive regulation of interleukin-10 secretion","type":"narrow"},{"name":"stimulation of interleukin-10 production","type":"narrow"},{"name":"up regulation of interleukin-10 production","type":"exact"},{"name":"up-regulation of interleukin-10 production","type":"exact"},{"name":"upregulation of interleukin-10 production","type":"exact"}],"termid":"GO:0032733"}


id: PBO:0048875
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgin A6 family member A","termid":"PBO:0048875"}


id: MONDO:0035469
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete primary lymphedema without systemic or visceral involvement (obsolete MONDO:0035469)","secondary_identifiers":["Orphanet:568041"],"termid":"MONDO:0035469","xrefs":{"Monarch":{"xref_id":"0035469"}}}


id: MONDO:0014886
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  {"annotated_genes":["SJAG_02978"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86452],"is_not":false,"summary":null,"term":"MONDO:0014886"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"excluded_subClassOf","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"hyperpigmentation of the skin","termid":"MONDO:0019289"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02978":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"severe growth deficiency-strabismus-extensive dermal melanocytosis-intellectual disability syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:934712","GARD:17895","Orphanet:488627","UMLS:C4310745","OMIM:617051"],"synonyms":[{"name":"MRT55","type":"exact"},{"name":"intellectual disability, autosomal recessive 55","type":"exact"},{"name":"intellectual disability, autosomal recessive type 55","type":"exact"},{"name":"mental retardation, autosomal recessive 55","type":"exact"},{"name":"mental retardation, autosomal recessive type 55","type":"exact"},{"name":"neurodevelopmental disorder with microcephaly and gray sclerae","type":"exact"},{"name":"neurodevelopmental disorder with microcephaly and grey sclerae","type":"exact"}],"termid":"MONDO:0014886","terms_by_termid":{"MONDO:0014886":null},"xrefs":{"Monarch":{"xref_id":"0014886"}}}


id: PBO:0058711
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  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 6839","termid":"PBO:0058711"}


id: MONDO:0003083
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare slow growing benign tumor of aberrant and ectatic venous connections.","direct_ancestors":[{"relation_name":"is_a","term_name":"hemangioma","termid":"MONDO:0006500"},{"relation_name":"is_a","term_name":"congenital anomaly of cardiovascular system","termid":"MONDO:0024239"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"venous hemangioma","secondary_identifiers":["MEDGEN:90801","NCIT:C4296","ICDO:9122/0","SCTID:403968005","UMLS:C0334532","DOID:467","ICD9:228.09"],"synonyms":[{"name":"Venous angioma","type":"exact"},{"name":"Venous malformation","type":"exact"}],"termid":"MONDO:0003083","xrefs":{"Monarch":{"xref_id":"0003083"}}}


id: PR:O94588
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  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cuf2 gene.","definition_xrefs":["UniProtKB:O94588","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"copper-binding regulatory protein cuf2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC584.02","synonyms":[{"name":"Spom972h-cuf2","type":"exact"},{"name":"copper homeostasis protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94588"}


id: PBO:0027880
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  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_H4-K20_monomethylation","termid":"PBO:0027880"}


id: MONDO:0003143
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A vascular lesion in the papillary dermis resulting from ectasia of pre-existing vessels. It is associated with secondary proliferative changes in the overlying epidermis (hyperkeratosis). It can present with widespread lesions (angiokeratoma corporis diffusum, often associated with inborn errors of metabolism) or as a localized lesion (angiokeratoma of Fordyce, angiokeratoma circumscriptum, and angiokeratoma of Mibelli).","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin hemangioma","termid":"MONDO:0003110"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"angiokeratoma","secondary_identifiers":["icd11.foundation:533651286","MEDGEN:1542","CSP:2007-0683","SCTID:254788004","UMLS:C0002985","DOID:479","NCIT:C2874","NCIT:C4488","MESH:D000794"],"synonyms":[{"name":"angiokeratoma (morphologic abnormality)","type":"exact"},{"name":"angiokeratoma of skin","type":"exact"},{"name":"angiokeratoma of the skin","type":"exact"},{"name":"cutaneous angiokeratoma","type":"exact"},{"name":"skin angiokeratoma","type":"exact"}],"termid":"MONDO:0003143","xrefs":{"Monarch":{"xref_id":"0003143"}}}


id: PBO:0038658
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acrosin","termid":"PBO:0038658"}


id: PBO:0003932
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy associated protein (predicted)","termid":"PBO:0003932"}


id: FYPO:0000746
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization does not occur. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell.","definition_xrefs":["PomBase:mah","PMID:21620704"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin cortical patch internalization","termid":"FYPO:0000743"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0004803"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0004803","FYPO:0000138","FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"abolished actin cortical patch internalization","synonyms":[{"name":"abolished F-actin patch internalization","type":"exact"},{"name":"abolished actin cortical patch internalisation","type":"exact"},{"name":"abolished actin cortical patch internalization during mitotic cell cycle","type":"related"},{"name":"abolished actin cortical patch internalization during vegetative growth","type":"exact"},{"name":"abolished actin patch internalization","type":"exact"},{"name":"actin cortical patch internalization abolished","type":"exact"}],"termid":"FYPO:0000746"}


id: MONDO:0019173
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Rabies is a viral zoonosis leading to a fatal encephalopathy if not treated.","definition_xrefs":["Orphanet:770"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viral infectious disease","termid":"MONDO:0005108"},{"relation_name":"is_a","term_name":"infectious disorder of the nervous system","termid":"MONDO:0020010"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"rabies","secondary_identifiers":["UMLS:C0034494","icd11.foundation:854762584","DOID:11260","NORD:1644","NCIT:C28182","ICD9:071","ICD10CM:A82","SCTID:14168008","MedDRA:10037742","GARD:7516","MEDGEN:48308","MESH:D011818"],"synonyms":[{"name":"lyssa","type":"exact"}],"termid":"MONDO:0019173","xrefs":{"Monarch":{"xref_id":"0019173"}}}


id: PBO:0030417
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_plasmid_loss","termid":"PBO:0030417"}


id: GO:1903560
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.","definition_xrefs":["GOC:TermGenie","GOC:kmv","PMID:24843024","PMID:24100226","GO_REF:0000068"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nitrile biosynthetic process","termid":"GO:0080028"},{"relation_name":"is_a","term_name":"L-amino acid biosynthetic process","termid":"GO:0170034"},{"relation_name":"is_a","term_name":"non-proteinogenic amino acid biosynthetic process","termid":"GO:0170043"},{"relation_name":"is_a","term_name":"3-cyano-L-alanine metabolic process","termid":"GO:1903558"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006520"],"is_obsolete":false,"name":"3-cyano-L-alanine biosynthetic process","synonyms":[{"name":"3-cyano-L-alanine anabolism","type":"exact"},{"name":"3-cyano-L-alanine biosynthesis","type":"exact"},{"name":"3-cyano-L-alanine formation","type":"exact"},{"name":"3-cyano-L-alanine synthesis","type":"exact"}],"termid":"GO:1903560"}


id: FYPO:0007687
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to nuclear exosome foci is normal (i.e. indistinguishable from wild type) during meiosis. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle.","definition_xrefs":["PMID:33574613","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization during meiosis","termid":"FYPO:0003790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000138"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257","FYPO:0000138"],"is_obsolete":false,"name":"normal protein localization to nuclear exosome focus during meiosis","synonyms":[{"name":"normal protein localisation to nuclear exosome focus during meiosis","type":"exact"},{"name":"normal protein localization to Mmi1 focus during meiosis","type":"exact"},{"name":"normal protein localization to Mmi1 nuclear focus during meiosis","type":"exact"},{"name":"normal protein localization to nuclear exosome foci during meiosis","type":"exact"},{"name":"normal protein localization to nuclear exosome focus during meiotic nuclear division","type":"exact"}],"termid":"FYPO:0007687"}


id: PBO:0030090
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_dipeptide_nitrogen_source","termid":"PBO:0030090"}


id: PBO:0070783
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 13","termid":"PBO:0070783"}


id: MONDO:0030718
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spermatogenic failure","termid":"MONDO:0004983"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"spermatogenic failure 67","secondary_identifiers":["DOID:0070566","OMIM:619803","UMLS:C5676947","MEDGEN:1804099"],"synonyms":[{"name":"SPGF67","type":"exact"},{"name":"spermatogenic failure 67","type":"exact"}],"termid":"MONDO:0030718","xrefs":{"Monarch":{"xref_id":"0030718"}}}


id: PBO:0038770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin related protein 8","termid":"PBO:0038770"}


id: GO:0097029
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.","definition_xrefs":["GOC:BHF","PMID:15845453"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myeloid leukocyte differentiation","termid":"GO:0002573"},{"relation_name":"is_a","term_name":"dendritic cell differentiation","termid":"GO:0097028"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mature conventional dendritic cell differentiation","termid":"GO:0097029"}


id: PBO:0085883
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; involved in energy metabolism under respiratory conditions; expression induced under carbon limitation and repressed under high glucose; RGI2 has a paralog, RGI1, that arose from the whole genome duplication","termid":"PBO:0085883"}


id: GO:0060755
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of leukocyte chemotaxis","termid":"GO:0002689"},{"relation_name":"is_a","term_name":"regulation of mast cell chemotaxis","termid":"GO:0060753"},{"relation_name":"negatively_regulates","term_name":"mast cell chemotaxis","termid":"GO:0002551"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of mast cell chemotaxis","termid":"GO:0060755"}


id: PBO:0114750
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitotic and meiotic cohesin unloading complex subunit Pds5","termid":"PBO:0114750"}


id: GO:0055097
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of molecular signals mediated by the detection of high density lipoprotein particle.","definition_xrefs":["GOC:BHF","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipoprotein particle mediated signaling","termid":"GO:0055095"},{"relation_name":"part_of","term_name":"cellular response to high density lipoprotein particle stimulus","termid":"GO:0071403"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"high density lipoprotein particle mediated signaling","synonyms":[{"name":"high density lipoprotein mediated signalling","type":"exact"},{"name":"high density lipoprotein particle mediated signal transduction","type":"exact"},{"name":"high density lipoprotein particle-mediated signaling","type":"exact"}],"termid":"GO:0055097"}


id: PBO:0028318
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-delayed_onset_of_mitochondrial_fission_during_cellular_response_to_hydrogen_peroxide","termid":"PBO:0028318"}


id: PBO:0029249
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-actin_filaments_present_in_increased_numbers","termid":"PBO:0029249"}


id: GO:0051899
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.","definition_xrefs":["Wikipedia:Depolarization","GOC:dh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of membrane potential","termid":"GO:0042391"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"membrane depolarization","secondary_identifiers":["Reactome:R-HSA-112308"],"termid":"GO:0051899"}


id: PBO:0060747
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B2","termid":"PBO:0060747"}


id: PBO:0074127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 30 member 10","termid":"PBO:0074127"}


id: PBO:0048253
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"galactose-3-O-sulfotransferase 1","termid":"PBO:0048253"}


id: GO:0050819
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of coagulation","termid":"GO:0050818"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"negatively_regulates","term_name":"coagulation","termid":"GO:0050817"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of coagulation","synonyms":[{"name":"anticoagulant activity","type":"related"},{"name":"down regulation of coagulation","type":"exact"},{"name":"down-regulation of coagulation","type":"exact"},{"name":"downregulation of coagulation","type":"exact"},{"name":"inhibition of coagulation","type":"narrow"},{"name":"negative regulation of clotting","type":"exact"}],"termid":"GO:0050819"}


id: PBO:0054263
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1648","termid":"PBO:0054263"}


id: FYPO:0003050
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type). Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci.","definition_xrefs":["PomBase:mah","GO:0007129"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular component organization","termid":"FYPO:0006003"},{"relation_name":"is_a","term_name":"normal meiotic cell cycle process","termid":"FYPO:0007078"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal homologous chromosome pairing","synonyms":[{"name":"normal homologous chromosome pairing at meiosis","type":"exact"},{"name":"normal synapsis","type":"exact"}],"termid":"FYPO:0003050"}


id: PBO:0048819
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G protein subunit gamma 5 pseudogene 3","termid":"PBO:0048819"}


id: MONDO:0100496
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare inherited muscular dystrophy characterized by the coexistence of limb-girdle weakness and early-onset diffuse joint contractures without cardiomyopathy.","definition_xrefs":["PMID:26581302"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive titinopathy","termid":"MONDO:0100493"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005336","MONDO:0002320"],"is_obsolete":false,"name":"Emery-Dreifuss-like muscular dystrophy","termid":"MONDO:0100496","xrefs":{"Monarch":{"xref_id":"0100496"}}}


id: PBO:0084503
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Meiosis-specific protein that localizes to chromosomes; prevents synapsis between nonhomologous chromosomes and ensures synapsis between homologs; forms complex with Mnd1p to promote homolog pairing and meiotic double-strand break repair; heterodimer of Hop2p-Mnd1p stimulates the Dmc1p-mediated strand invasion","termid":"PBO:0084503"}


id: PBO:0091723
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human CDK1","termid":"PBO:0091723"}


id: PBO:0070675
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7 pseudogene 46","termid":"PBO:0070675"}


id: GO:0044633
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism.","definition_xrefs":["PMID:20837040","GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation of complement activation, alternative pathway in another organism (obsolete GO:0044633)","synonyms":[{"name":"modulation of complement activation, alternative pathway in other organism","type":"exact"},{"name":"regulation of complement activation, alternative pathway in other organism","type":"related"}],"termid":"GO:0044633"}


id: FYPO:0001420
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a population of cells grow at the same rate as wild type in the vegetative growth phase of the life cycle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"},{"relation_name":"is_a","term_name":"normal cell population growth rate","termid":"FYPO:0001419"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0000139"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002060","FYPO:0000139","FYPO:0002057","FYPO:0000257","FYPO:0002058"],"is_obsolete":false,"name":"normal vegetative cell population growth rate","synonyms":[{"name":"normal growth rate","type":"broad"},{"name":"normal vegetative cell population proliferation","type":"related"},{"name":"normal vegetative cell proliferation","type":"related"}],"termid":"FYPO:0001420"}


id: PBO:0068713
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4atac small nuclear 2, pseudogene","termid":"PBO:0068713"}


id: GO:1903328
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of RNA metabolic process","termid":"GO:0051254"},{"relation_name":"is_a","term_name":"regulation of tRNA metabolic process","termid":"GO:1903326"},{"relation_name":"positively_regulates","term_name":"tRNA metabolic process","termid":"GO:0006399"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0006399"},{"rel_name":"regulates","termid":"GO:0006399"}],"interesting_parent_ids":["GO:0008150","GO:0006399"],"is_obsolete":false,"name":"positive regulation of tRNA metabolic process","synonyms":[{"name":"activation of tRNA metabolic process","type":"narrow"},{"name":"activation of tRNA metabolism","type":"narrow"},{"name":"positive regulation of tRNA metabolism","type":"exact"},{"name":"up regulation of tRNA metabolic process","type":"exact"},{"name":"up regulation of tRNA metabolism","type":"exact"},{"name":"up-regulation of tRNA metabolic process","type":"exact"},{"name":"up-regulation of tRNA metabolism","type":"exact"},{"name":"upregulation of tRNA metabolic process","type":"exact"},{"name":"upregulation of tRNA metabolism","type":"exact"}],"termid":"GO:1903328"}


id: PR:P36587
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An NADPH--cytochrome P450 reductase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO03316","PANTHER:PTHR19384:SF17","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADPH--cytochrome P450 reductase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC29A10.01","secondary_identifiers":["UniProtKB:P36587"],"synonyms":[{"name":"CPR (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"P450R (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-POR","type":"exact"}],"termid":"PR:P36587"}


id: PBO:0025424
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA repair-deficiency disorders","termid":"PBO:0025424"}


id: GO:1902912
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex which is capable of pyruvate kinase activity.","definition_xrefs":["GOC:bhm","GOC:TermGenie","PMID:24606918","GO_REF:0000088"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase complex, transferring phosphorus-containing groups","termid":"GO:0061695"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"pyruvate kinase complex","termid":"GO:1902912"}


id: PBO:0065546
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prostaglandin D2 synthase","termid":"PBO:0065546"}


id: MONDO:0021845
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A syndrome characterized by a unilateral linear basal cell nevus, diffuse osteoma cutis, unilateral anodontia (missing teeth), and abnormal bone mineralization. This is an n-of-1 use case where only one patient or family has been described with this disorder.","definition_xrefs":["PMID:2715453"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"anodontia","termid":"MONDO:0008797"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Aloi Tomasini Isaia syndrome","secondary_identifiers":["UMLS:C2931405","GARD:417","MEDGEN:419073","MESH:C537049"],"synonyms":[{"name":"basal cell nevus anodontia abnormal bone mineralization","type":"exact"},{"name":"basal cell nevus, anodontia, abnormal bone mineralization","type":"related"},{"name":"unilateral linear basal cell nevus associated with diffuse osteoma cutis, unilateral anodontia, and abnormal bone mineralization","type":"related"}],"termid":"MONDO:0021845","xrefs":{"Monarch":{"xref_id":"0021845"}}}


id: MONDO:1010226
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Lymphangiosarcoma that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sarcoma, non-human animal","termid":"MONDO:0700131"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lymphangiosarcoma, non-human animal","secondary_identifiers":["OMIA:002476"],"termid":"MONDO:1010226","xrefs":{"Monarch":{"xref_id":"1010226"}}}


id: MONDO:0002949
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A histologic variant of basal cell carcinoma of the skin characterized by the presence of strands and nests of malignant cells that are embedded in a dense fibrotic stroma.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin basal cell carcinoma","termid":"MONDO:0005341"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005093"],"is_obsolete":false,"name":"morpheaform basal cell carcinoma","secondary_identifiers":["NCIT:C27182","MEDGEN:107825","DOID:4292","SCTID:403913006","UMLS:C0555191"],"synonyms":[{"name":"basal cell carcinoma sclerosing type","type":"exact"},{"name":"basal cell carcinoma, morphea","type":"exact"},{"name":"cicatricial basal-cell carcinoma","type":"exact"},{"name":"morphea-type (sclerosing) basal cell carcinoma","type":"exact"},{"name":"morphea-type basal cell carcinoma","type":"exact"},{"name":"morpheaform basal cell carcinoma","type":"exact"},{"name":"sclerosing type basal cell carcinoma","type":"exact"},{"name":"skin morphea-type (sclerosing) basal cell carcinoma","type":"exact"}],"termid":"MONDO:0002949","xrefs":{"Monarch":{"xref_id":"0002949"}}}


id: PBO:0045803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"erythroid differentiation regulatory factor 1","termid":"PBO:0045803"}


id: FYPO:0000623
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transcription regulation phenotype in which any process of positive regulation of transcription is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal regulation of transcription","termid":"FYPO:0004526"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0006551","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abnormal positive regulation of transcription","synonyms":[{"name":"abnormal activation of gene-specific transcription","type":"related"},{"name":"abnormal activation of transcription, DNA-dependent","type":"narrow"},{"name":"abnormal positive regulation of cellular transcription, DNA-dependent","type":"exact"},{"name":"abnormal positive regulation of gene-specific transcription","type":"related"},{"name":"abnormal positive regulation of transcription, DNA-dependent","type":"exact"},{"name":"abnormal stimulation of gene-specific transcription","type":"narrow"},{"name":"abnormal stimulation of transcription, DNA-dependent","type":"narrow"},{"name":"abnormal up regulation of gene-specific transcription","type":"related"},{"name":"abnormal up regulation of transcription, DNA-dependent","type":"exact"},{"name":"abnormal up-regulation of gene-specific transcription","type":"related"},{"name":"abnormal up-regulation of transcription, DNA-dependent","type":"exact"},{"name":"abnormal upregulation of gene-specific transcription","type":"related"},{"name":"abnormal upregulation of transcription, DNA-dependent","type":"exact"}],"termid":"FYPO:0000623"}


id: PR:O74780
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC25B2.08 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74780"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C25B2.08 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC25B2.08","synonyms":[{"name":"Spom972h-SPBC25B2.08","type":"exact"}],"termid":"PR:O74780"}


id: GO:0001840
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.","definition_xrefs":["GOC:ef","ISBN:0878932585","GOC:dph","ISBN:0878932437"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelium development","termid":"GO:0060429"},{"relation_name":"part_of","term_name":"chordate embryonic development","termid":"GO:0043009"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"neural plate development","termid":"GO:0001840"}


id: MONDO:0018775
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete axonal hereditary motor and sensory neuropathy (obsolete MONDO:0018775)","secondary_identifiers":["Orphanet:476109"],"synonyms":[{"name":"axonal HMSN","type":"exact"}],"termid":"MONDO:0018775","xrefs":{"Monarch":{"xref_id":"0018775"}}}


id: GO:1900491
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly.","definition_xrefs":["GOC:mengo_curators","GOC:pr","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of iron-sulfur cluster assembly","termid":"GO:1903329"},{"relation_name":"regulates","term_name":"[4Fe-4S] cluster assembly","termid":"GO:0044572"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0016226"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0016226"],"is_obsolete":false,"name":"regulation of [4Fe-4S] cluster assembly","synonyms":[{"name":"regulation of 4Fe-4S cluster assembly","type":"exact"},{"name":"regulation of [4Fe-4S] cluster biosynthetic process","type":"related"}],"termid":"GO:1900491"}


id: PBO:0036383
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human DPS1","termid":"PBO:0036383"}


id: PBO:0064865
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PPP1R21 divergent transcript","termid":"PBO:0064865"}


id: MONDO:0011183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"bone Paget disease","termid":"MONDO:0005382"},{"relation_name":"is_a","term_name":"primary osteolysis","termid":"MONDO:0019707"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Paget disease of bone 2, early-onset","secondary_identifiers":["DOID:0081365","OMIM:602080","UMLS:C4085251","MEDGEN:899166"],"synonyms":[{"name":"PDB2","type":"related"},{"name":"Paget disease of bone 2, early-onset","type":"exact"}],"termid":"MONDO:0011183","xrefs":{"Monarch":{"xref_id":"0011183"}}}


id: PBO:0039558
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat domain containing 50","termid":"PBO:0039558"}


id: PBO:0075619
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sepiapterin reductase","termid":"PBO:0075619"}


id: PBO:0054364
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1757","termid":"PBO:0054364"}


id: FYPO:0008124
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A abnormal nuclear envelope organization phenotype in which SPB fenestra in the nuclear envelope are larger than normal. SPB fenestra are the result of SPB extrusion.","definition_xrefs":["PMID:37783794"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nuclear envelope organization","termid":"FYPO:0000815"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"increased nuclear envelope SPB fenestra size","termid":"FYPO:0008124"}


id: FYPO:0007402
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of protein complex organization is abnormal.","definition_xrefs":["GO:0043933","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular component organization during vegetative growth","termid":"FYPO:0001353"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"abnormal protein complex organization during vegetative growth","synonyms":[{"name":"abnormal protein complex organisation during vegetative growth","type":"exact"},{"name":"abnormal protein complex organization during mitotic cell cycle","type":"related"},{"name":"abnormal protein-containing complex subunit organization during vegetative growth","type":"exact"}],"termid":"FYPO:0007402"}


id: PBO:0113361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein serine/threonine kinase; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress","termid":"PBO:0113361"}


id: PBO:0087851
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transaldolase of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift; NQM1 has a paralog, TAL1, that arose from the whole genome duplication","termid":"PBO:0087851"}


id: GO:0032124
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.","definition_xrefs":["PMID:10503190","GOC:dph","GOC:jl","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleus organization","termid":"GO:0006997"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"macronucleus organization","synonyms":[{"name":"macronuclear organization","type":"exact"},{"name":"macronuclear organization and biogenesis","type":"related"},{"name":"macronucleus organisation","type":"exact"}],"termid":"GO:0032124"}


id: FYPO:0007540
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the tyrosine residue at position 1 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:30282034","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein phosphorylation during vegetative growth","termid":"FYPO:0000776"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001312","FYPO:0000257"],"is_obsolete":false,"name":"normal phosphorylation of RNA polymerase II C-terminal domain tyrosine 1 residues during vegetative growth","synonyms":[{"name":"normal phosphorylation of RNA polymerase II C-terminal domain tyrosine 1 residues during mitotic cell cycle","type":"related"},{"name":"normal phosphorylation of RNA polymerase II CTD tyrosine 1 residues during vegetative growth","type":"exact"}],"termid":"FYPO:0007540"}


id: PBO:0018209
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyridoxal family transmembrane transporter (predicted)","termid":"PBO:0018209"}


id: PBO:0067325
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 416, pseudogene","termid":"PBO:0067325"}


id: PBO:0056865
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule associated monooxygenase, calponin and LIM domain containing 1","termid":"PBO:0056865"}


id: PBO:0076499
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"taste 1 receptor member 2","termid":"PBO:0076499"}


id: GO:0044609
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD.","definition_xrefs":["PMID:22446626","GOC:sp"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein-containing complex","termid":"GO:0140535"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"DBIRD complex","termid":"GO:0044609"}


id: GO:0032737
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate, or extent of interleukin-14 production.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of interleukin-14 production (obsolete GO:0032737)","synonyms":[{"name":"activation of interleukin-14 production","type":"narrow"},{"name":"positive regulation of IL-14 production","type":"exact"},{"name":"positive regulation of interleukin-14 biosynthetic process","type":"narrow"},{"name":"stimulation of interleukin-14 production","type":"narrow"},{"name":"up regulation of interleukin-14 production","type":"exact"},{"name":"up-regulation of interleukin-14 production","type":"exact"},{"name":"upregulation of interleukin-14 production","type":"exact"}],"termid":"GO:0032737"}


id: MONDO:0007435
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Dentatorubral pallidoluysian atrophy (DRPLA) is a rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I). It is characterized by involuntary movements, ataxia, epilepsy, mental disorders, cognitive decline and prominent anticipation.","definition_xrefs":["Orphanet:101"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Huntington disease-like syndrome","termid":"MONDO:0015548"},{"relation_name":"is_a","term_name":"autosomal dominant cerebellar ataxia type IV","termid":"MONDO:0019794"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0002039","MONDO:0005559"],"is_obsolete":false,"name":"dentatorubral-pallidoluysian atrophy","secondary_identifiers":["MEDGEN:155630","MESH:D020191","NANDO:1200043","NCIT:C122653","SCTID:267581004","UMLS:C0751781","SCTID:68116008","DOID:0060162","ICD9:333.99","NCIT:C7636","OMIM:125370","GARD:5643"],"synonyms":[{"name":"DRPLA","type":"exact"},{"name":"Dentatorubropallidoluysian atrophy","type":"exact"},{"name":"NOD","type":"related"},{"name":"Naito Oyanagi disease","type":"related"},{"name":"Naito-Oyanagi disease","type":"exact"},{"name":"ataxia, chorea, seizures, and dementia","type":"related"},{"name":"dentatorubral pallidoluysian atrophy","type":"related"},{"name":"dentatorubral-pallidoluysian atrophy","type":"exact"},{"name":"haw River syndrome","type":"exact"},{"name":"myoclonic epilepsy with choreoathetosis","type":"related"}],"termid":"MONDO:0007435","xrefs":{"Monarch":{"xref_id":"0007435"}}}


id: GO:0035071
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.","definition_xrefs":["GOC:bf","PMID:10882130","GOC:mtg_apoptosis"],"gene_count":0,"genotype_count":0,"name":"obsolete salivary gland cell autophagic cell death (obsolete GO:0035071)","termid":"GO:0035071"}


id: MONDO:0019050
data:
  {"annotated_genes":["SJAG_04334","SJAG_00839","SJAG_01351","SJAG_04495","SJAG_00988","SJAG_00235","SJAG_01162","SJAG_02796","SJAG_04217","SJAG_03929","SJAG_02297"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85579],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010480"},{"annotations":[86240],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009259"},{"annotations":[86544],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009284"},{"annotations":[86516],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013275"},{"annotations":[87192],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0019531"},{"annotations":[86323],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009606"},{"annotations":[85872,85871],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009605"},{"annotations":[86799,86798],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009340"},{"annotations":[85934],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0009950"}]},"cv_name":"mondo","definition":"An inherited disorder characterized by structural alterations of a globin chain within the hemoglobin molecule.","definition_xrefs":["NCIT:C3092"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"familial hemolytic anemia","termid":"MONDO:0003689"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"hemoglobinopathy","termid":"MONDO:0044348"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00235":null,"SJAG_00839":null,"SJAG_00988":null,"SJAG_01162":null,"SJAG_01351":null,"SJAG_02297":null,"SJAG_02796":null,"SJAG_03929":null,"SJAG_04217":null,"SJAG_04334":null,"SJAG_04495":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"inherited hemoglobinopathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MedDRA:10060892","ICD10CM:D58.0","ICD9:282.7","Orphanet:68364","DOID:2860","MESH:D006453","SCTID:427306008","ICD10CM:D58.1","GARD:18883"],"synonyms":[{"name":"Hemoglobinopathies / iron metabolism","type":"exact"},{"name":"hemoglobinopathies","type":"exact"},{"name":"hemoglobinopathy","type":"related"},{"name":"hereditary hemoglobinopathy","type":"exact"}],"termid":"MONDO:0019050","terms_by_termid":{"MONDO:0009259":null,"MONDO:0009284":null,"MONDO:0009340":null,"MONDO:0009605":null,"MONDO:0009606":null,"MONDO:0009950":null,"MONDO:0010480":null,"MONDO:0013275":null,"MONDO:0019531":null},"xrefs":{"Monarch":{"xref_id":"0019050"}}}


id: PBO:0053457
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 410","termid":"PBO:0053457"}


id: PBO:0054325
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1718","termid":"PBO:0054325"}


id: MONDO:0020842
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Medullary carcinoma may refer to one of several different tumors of epithelial origin. As the term 'medulla' is a generic anatomic descriptor for the mid-layer of various organ tissues, a medullary tumor usually arises from the 'mid-layer tissues' of the relevant organ.","definition_xrefs":["Wikipedia:Medullary_carcinoma"],"gene_count":0,"genotype_count":0,"name":"obsolete medullary carcinoma (obsolete MONDO:0020842)","secondary_identifiers":["NCIT:C8998"],"termid":"MONDO:0020842","xrefs":{"Monarch":{"xref_id":"0020842"}}}


id: GO:1990857
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. An anaphase promoting complex bound to an activator in the Fzr1 (human)/Mfr1 (pombe) family.","definition_xrefs":["PMID:11493649"],"gene_count":0,"genotype_count":0,"name":"obsolete APC-Fzr1/Mfr1 complex (obsolete GO:1990857)","termid":"GO:1990857"}


id: GO:0038022
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.","definition_xrefs":["PMID:21041441","GOC:sart","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor activity","termid":"GO:0004930"},{"relation_name":"is_a","term_name":"olfactory receptor activity","termid":"GO:0004984"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0038023"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"G protein-coupled olfactory receptor activity","synonyms":[{"name":"G-protein coupled odorant receptor activity","type":"exact"},{"name":"G-protein coupled olfactory receptor activity","type":"exact"},{"name":"odorant receptor activity, G-protein coupled","type":"narrow"},{"name":"olfactory receptor activity, G-protein coupled","type":"exact"}],"termid":"GO:0038022"}


id: GO:0120034
data:
  {"annotated_genes":["SJAG_04509","SJAG_02379","SJAG_01794","SJAG_00514","SJAG_03453"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[93806,111742,91174,88213,90193],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1902917"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell projection organization","termid":"GO:0031346"},{"relation_name":"is_a","term_name":"positive regulation of cellular component biogenesis","termid":"GO:0044089"},{"relation_name":"is_a","term_name":"regulation of plasma membrane bounded cell projection assembly","termid":"GO:0120032"},{"relation_name":"positively_regulates","term_name":"plasma membrane bounded cell projection assembly","termid":"GO:0120031"}],"gene_count":5,"genes_by_uniquename":{"SJAG_00514":null,"SJAG_01794":null,"SJAG_02379":null,"SJAG_03453":null,"SJAG_04509":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150"],"is_obsolete":false,"name":"positive regulation of plasma membrane bounded cell projection assembly","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0120034","terms_by_termid":{"GO:1902917":null}}


id: PBO:0117163
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDKN2B and CDKN2A antisense cis and trans regulatory RNA 1","termid":"PBO:0117163"}


id: FYPO:0007325
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which an interaction between a protein and a transfer RNA (tRNA) is increased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein-RNA interaction","termid":"FYPO:0002135"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002131"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0001985","FYPO:0002131","FYPO:0000652"],"is_obsolete":false,"name":"increased tRNA binding","synonyms":[{"name":"increased protein-tRNA interaction","type":"exact"},{"name":"increased protein-transfer RNA interaction","type":"exact"},{"name":"increased transfer RNA binding","type":"exact"}],"termid":"FYPO:0007325"}


id: PBO:0045063
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"discs large MAGUK scaffold protein 3","termid":"PBO:0045063"}


id: PATO:0000385
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000385 hardness value (obsolete PATO:0000385)","termid":"PATO:0000385"}


id: PR:Q9HE05
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A ubiquitin conjugation factor E4 B that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00878","PANTHER:PTHR13931:SF2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin conjugation factor E4 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC20H4.10","secondary_identifiers":["UniProtKB:Q9HE05"],"synonyms":[{"name":"Spom972h-UBE4B","type":"exact"},{"name":"UB fusion protein 2 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquitin fusion degradation protein 2 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9HE05"}


id: MONDO:0010480
data:
  {"annotated_genes":["SJAG_02297"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85579],"is_not":false,"summary":null,"term":"MONDO:0010480"}]},"cv_name":"mondo","definition":"Any nonspherocytic hemolytic anemia in which the cause of the disease is a variation in the G6PD gene resulting in severely decreased activity levels of the enzyme glucose-6-phosphate dehydrogenase. Individuals with hemizygous or homozygous G6PD variants associated with chronic nonspherocytic hemolytic anemia (CNSHA) will clinically manifest CNSHA. Individuals with G6PD variants that cause CNSHA are at risk for severe neonatal jaundice and acute exacerbation of their chronic hemolytic anemia in response to certain medication exposures, chemical exposures, infections, or consumption of fava beans.","direct_ancestors":[{"relation_name":"is_a","term_name":"anemia, nonspherocytic hemolytic","termid":"MONDO:0000105"},{"relation_name":"is_a","term_name":"G6PD deficiency","termid":"MONDO:0005775"},{"relation_name":"is_a","term_name":"inborn disorder of pentose phosphate metabolism","termid":"MONDO:0019231"},{"relation_name":"is_a","term_name":"anemia due to erythrocyte enzyme disorder","termid":"MONDO:0020585"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02297":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0002280","MONDO:0005066","MONDO:0005570"],"is_obsolete":false,"name":"anemia, nonspherocytic hemolytic, due to G6PD deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:C567533","Orphanet:466026","GARD:6520","MEDGEN:403555","OMIM:300908","UMLS:C2720289"],"synonyms":[{"name":"Class I G6PD deficiency","type":"exact"},{"name":"anemia, congenital, nonspherocytic hemolytic, 1, G6PD deficient","type":"exact"},{"name":"anemia, nonspherocytic hemolytic, due to G6PD deficiency","type":"exact"},{"name":"class I glucose-6-phosphate dehydrogenase deficiency","type":"exact"},{"name":"hemolytic anaemia due to G6PD deficiency","type":"exact"},{"name":"hemolytic anemia due to G6PD deficiency","type":"exact"},{"name":"hemolytic anemia, G6PD deficient (favism), X-linked dominant","type":"exact"},{"name":"severe hemolytic anaemia due to G6PD deficiency","type":"exact"},{"name":"severe hemolytic anemia due to G6PD deficiency","type":"exact"}],"termid":"MONDO:0010480","terms_by_termid":{"MONDO:0010480":null},"xrefs":{"Monarch":{"xref_id":"0010480"}}}


id: MONDO:0017966
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete 46,XY disorder of gonadal development (obsolete MONDO:0017966)","secondary_identifiers":["Orphanet:325118"],"termid":"MONDO:0017966","xrefs":{"Monarch":{"xref_id":"0017966"}}}


id: FYPO:0002610
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at centromeric outer repeat regions. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal histone H2A phosphorylation during vegetative growth","termid":"FYPO:0002601"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001312","FYPO:0000257"],"is_obsolete":false,"name":"normal histone H2A phosphorylation at centromere outer repeat during vegetative growth","synonyms":[{"name":"abnormal histone H2A phosphorylation at centromere otr during vegetative growth","type":"exact"},{"name":"abnormal histone H2A phosphorylation at centromere outer repeat during vegetative growth","type":"exact"},{"name":"abnormal histone H2A phosphorylation at pericentric region during vegetative growth","type":"related"},{"name":"abnormal histone H2A phosphorylation at pericentromeric region during vegetative growth","type":"related"},{"name":"normal histone H2A phosphorylation at centromere outer repeat during mitotic cell cycle","type":"related"}],"termid":"FYPO:0002610"}


id: PBO:0060225
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"matrix remodeling associated 7","termid":"PBO:0060225"}


id: PBO:0057829
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR3147 host gene","termid":"PBO:0057829"}


id: MONDO:1011102
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Renal agenesis that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal agenesis, non-human animal","termid":"MONDO:1010272"},{"relation_name":"is_a","term_name":"renal disease, dog","termid":"MONDO:1012235"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"renal agenesis, dog","secondary_identifiers":["OMIA:002007-9615"],"termid":"MONDO:1011102","xrefs":{"Monarch":{"xref_id":"1011102"}}}


id: GO:0051322
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.","definition_xrefs":["GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle phase","termid":"GO:0022403"},{"relation_name":"part_of","term_name":"M phase","termid":"GO:0000279"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"anaphase","secondary_identifiers":["Wikipedia:Anaphase"],"termid":"GO:0051322"}


id: PBO:0090232
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myo-inositol transmembrane transporter","termid":"PBO:0090232"}


id: FYPO:0007803
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which macroautophagy does not occur when the cell is subject to leucine starvation.","definition_xrefs":["PomBase:mah","PMID:33534698","GO:0016236"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished macroautophagy","termid":"FYPO:0000380"},{"relation_name":"is_a","term_name":"abnormal metabolic process","termid":"FYPO:0000860"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abolished macroautophagy during leucine starvation","synonyms":[{"name":"abolished macroautophagy during cellular response to leucine starvation","type":"exact"},{"name":"abolished macroautophagy during leucine depletion","type":"exact"},{"name":"abolished macroautophagy during leucine deprivation","type":"exact"},{"name":"macroautophagy abolished during leucine starvation","type":"exact"}],"termid":"FYPO:0007803"}


id: PBO:0043561
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type V alpha 3 chain","termid":"PBO:0043561"}


id: PBO:0076029
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine kinase 25 pseudogene 1","termid":"PBO:0076029"}


id: GO:0051518
data:
  {"annotated_genes":["SJAG_00514","SJAG_03581","SJAG_02392"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90189,94911,96178],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051519"}]},"cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of unidimensional cell growth","termid":"GO:0051512"},{"relation_name":"is_a","term_name":"regulation of bipolar cell growth","termid":"GO:0051516"},{"relation_name":"positively_regulates","term_name":"bipolar cell growth","termid":"GO:0042815"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00514":null,"SJAG_02392":null,"SJAG_03581":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of bipolar cell growth","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"stimulation of bipolar cell growth","type":"narrow"},{"name":"up regulation of bipolar cell growth","type":"exact"},{"name":"up-regulation of bipolar cell growth","type":"exact"},{"name":"upregulation of bipolar cell growth","type":"exact"}],"termid":"GO:0051518","terms_by_termid":{"GO:0051519":null}}


id: GO:0004341
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.","definition_xrefs":["EC:3.1.1.17"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016788"],"is_obsolete":false,"name":"gluconolactonase activity","secondary_identifiers":["MetaCyc:GLUCONOLACT-RXN","RHEA:10440"],"synonyms":[{"name":"D-glucono-1,5-lactone lactonohydrolase activity","type":"related"},{"name":"aldonolactonase activity","type":"related"},{"name":"glucono-delta-lactonase activity","type":"related"},{"name":"gulonolactonase activity","type":"related"},{"name":"lactonase activity","type":"broad"}],"termid":"GO:0004341"}


id: FYPO:0004067
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a lower extent than normal.","definition_xrefs":["GO:0071619","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein phosphorylation during vegetative growth","termid":"FYPO:0001838"},{"relation_name":"is_a","term_name":"abnormal RNA polymerase II C-terminal domain phosphorylation","termid":"FYPO:0007410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002274","FYPO:0001320","FYPO:0000002","FYPO:0005447","FYPO:0002494"],"is_obsolete":false,"name":"decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth","synonyms":[{"name":"decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during mitotic cell cycle","type":"related"},{"name":"decreased phosphorylation of RNA polymerase II CTD serine 2 residues during vegetative growth","type":"exact"},{"name":"reduced phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth","type":"exact"}],"termid":"FYPO:0004067"}


id: PBO:0012547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"20S proteasome complex subunit alpha 3 (predicted)","termid":"PBO:0012547"}


id: PBO:0059697
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO2 pseudogene 5","termid":"PBO:0059697"}


id: PBO:0004562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin Snx3 (predicted)","termid":"PBO:0004562"}


id: GO:0034759
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of iron ion transport","termid":"GO:0034756"},{"relation_name":"is_a","term_name":"regulation of monoatomic cation transmembrane transport","termid":"GO:1904062"},{"relation_name":"regulates","term_name":"iron ion transmembrane transport","termid":"GO:0034755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0055085","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"regulation of iron ion transmembrane transport","synonyms":[{"name":"regulation of iron ion membrane transport","type":"exact"},{"name":"regulation of transmembrane Fe transport","type":"exact"},{"name":"regulation of transmembrane iron ion transport","type":"exact"},{"name":"regulation of transmembrane iron transport","type":"exact"}],"termid":"GO:0034759"}


id: MONDO:1010564
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital adrenal hyperplasia that occurs in rabbit.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital adrenal hyperplasia, non-human animal","termid":"MONDO:1010050"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital adrenal hyperplasia, rabbit","secondary_identifiers":["OMIA:000017-9986"],"termid":"MONDO:1010564","xrefs":{"Monarch":{"xref_id":"1010564"}}}


id: SO:0002003
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A mating type region motif, the rightmost segment of homology in the HML and MAT mating loci (not present in HMR).","definition_xrefs":["SGD:jd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mating_type_region_motif","termid":"SO:0001999"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Z2_region","synonyms":[{"name":"Z2-segment","type":"exact"}],"termid":"SO:0002003"}


id: PBO:0027440
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_level_in_stationary_phase","termid":"PBO:0027440"}


id: FYPO:0003764
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with one nucleus and no septum, and then die.","definition_xrefs":["PomBase:mah","PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inviable after spore germination, single or double cell division, arrest with single nucleus","termid":"FYPO:0003759"},{"relation_name":"is_a","term_name":"inviable aseptate mononucleate vegetative cell","termid":"FYPO:0003763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000631"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"has_part","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0000032"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000631","FYPO:0005447","FYPO:0000002","FYPO:0000004","FYPO:0000032"],"is_obsolete":false,"name":"inviable after spore germination, single or double cell division, arrest with aseptate mononucleate cell","synonyms":[{"name":"inviable following spore germination, single or double cell division, arrest with aseptate mononucleate cell","type":"exact"},{"name":"inviable germinated spore, single or double cell division, arrest with aseptate mononucleate cell","type":"exact"},{"name":"lethal after spore germination, single or double cell division, arrest with aseptate mononucleate cell","type":"exact"}],"termid":"FYPO:0003764"}


id: GO:1903358
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of Golgi organization.","definition_xrefs":["PMID:17562788","GO_REF:0000058","GOC:als","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of organelle organization","termid":"GO:0033043"},{"relation_name":"regulates","term_name":"Golgi organization","termid":"GO:0007030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of Golgi organization","synonyms":[{"name":"regulation of Golgi organisation","type":"exact"},{"name":"regulation of Golgi organization and biogenesis","type":"related"}],"termid":"GO:1903358"}


id: GO:0000903
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods.","definition_xrefs":["GOC:vw","GOC:clt","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of cell shape during vegetative growth phase (obsolete GO:0000903)","synonyms":[{"name":"cell morphogenesis during vegetative growth phase","type":"related"},{"name":"cellular morphogenesis during vegetative growth","type":"related"},{"name":"regulation of cell morphogenesis during vegetative growth phase","type":"related"}],"termid":"GO:0000903"}


id: PBO:0006179
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-requires_regulator","termid":"PBO:0006179"}


id: PBO:0074373
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMG1 nonsense mediated mRNA decay associated PI3K related kinase","termid":"PBO:0074373"}


id: GO:0043231
data:
  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id: PBO:0045103
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id: GO:1905671
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id: MONDO:0005156
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id: PBO:0074065
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id: GO:0032219
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id: PBO:0071184
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id: MONDO:0002991
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  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma arising from the ovary. It is characterized by the presence of malignant epithelial cells in a fibrotic stroma. Histologic variants include clear cell, serous, mucinous, and endometrioid adenocarcinofibroma.","definition_xrefs":["NCIT:C40035"],"direct_ancestors":[{"relation_name":"is_a","term_name":"female reproductive organ cancer","termid":"MONDO:0001416"},{"relation_name":"is_a","term_name":"malignant mixed neoplasm","termid":"MONDO:0005853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"adenocarcinofibroma","secondary_identifiers":["MEDGEN:266966","UMLS:C1510778","DOID:4422"],"synonyms":[{"name":"adenocarcinofibroma","type":"exact"},{"name":"adenofibroma, malignant","type":"exact"},{"name":"malignant adenofibroma","type":"exact"}],"termid":"MONDO:0002991","xrefs":{"Monarch":{"xref_id":"0002991"}}}


id: PBO:0057915
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id: PBO:0004458
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id: PBO:0051118
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id: FYPO:0006196
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id: FYPO:0009003
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id: GO:0014713
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id: PR:O94685
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  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A RalBP1-associated Eps domain-containing protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02896","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UBA domain-containing protein 8 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC83.01","secondary_identifiers":["UniProtKB:O94685"],"synonyms":[{"name":"Spom972h-REPS1","type":"exact"}],"termid":"PR:O94685"}


id: GO:0140799
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + H+(in) = glycine(in) + H+(out).","definition_xrefs":["PMID:16701208","PMID:26912364"],"direct_ancestors":[{"relation_name":"is_a","term_name":"proton transmembrane transporter activity","termid":"GO:0015078"},{"relation_name":"is_a","term_name":"glycine transmembrane transporter activity","termid":"GO:0015187"},{"relation_name":"is_a","term_name":"amino acid:monoatomic cation antiporter activity","termid":"GO:0140848"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"glycine:proton antiporter activity","termid":"GO:0140799"}


id: PR:Q9P6M9
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 50S ribosomal protein L1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00732","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"54S ribosomal protein L1, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1610.02c","secondary_identifiers":["UniProtKB:Q9P6M9"],"synonyms":[{"name":"Spom972h-rplA","type":"exact"}],"termid":"PR:Q9P6M9"}


id: PBO:0044830
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"defensin beta 117 (pseudogene)","termid":"PBO:0044830"}


id: GO:0071648
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of chemokine production","termid":"GO:0032722"},{"relation_name":"is_a","term_name":"regulation of macrophage inflammatory protein-1 gamma production","termid":"GO:0071646"},{"relation_name":"positively_regulates","term_name":"macrophage inflammatory protein-1 gamma production","termid":"GO:0071607"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"positive regulation of macrophage inflammatory protein-1 gamma production","synonyms":[{"name":"positive regulation of CCL9 production","type":"exact"},{"name":"positive regulation of MIP-1g production","type":"exact"},{"name":"positive regulation of chemokine (C-C motif) ligand 9 production","type":"exact"}],"termid":"GO:0071648"}


id: MONDO:0018091
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Microcephaly-brachydactyly-kyphoscoliosis syndrome is characterized by profound intellectual deficit in association with microcephaly, short stature, brachydactyly type D, a flattened occiput, downslanting palpebral fissures, low-set large ears, a broad prominent nose and kyphoscoliosis. It has been described in three sisters. The disorder is likely to be transmitted as an autosomal recessive trait.","definition_xrefs":["Orphanet:3433"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"skeletal system disorder","termid":"MONDO:0005172"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"congenital limb malformation","termid":"MONDO:0019054"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microcephaly-brachydactyly-kyphoscoliosis syndrome","secondary_identifiers":["GARD:5490","UMLS:C2931177","MEDGEN:419731","SCTID:719378009","MESH:C536349"],"synonyms":[{"name":"Viljoen Kallis Voges syndrome","type":"related"},{"name":"Viljoen-Kallis-Voges syndrome","type":"exact"},{"name":"microcephaly brachydactyly kyphoscoliosis","type":"related"},{"name":"microcephaly, short stature, brachydactyly type D, flattened occiput, low-set large ears, prominent nose, kyphoscoliosis and intellectual disability","type":"related"}],"termid":"MONDO:0018091","xrefs":{"Monarch":{"xref_id":"0018091"}}}


id: FYPO:0003375
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of ubiquinone binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal molecular function","termid":"FYPO:0000706"},{"relation_name":"is_a","term_name":"binding phenotype","termid":"FYPO:0001092"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000257"],"is_obsolete":false,"name":"normal ubiquinone binding","synonyms":[{"name":"normal coenzyme Q binding","type":"exact"}],"termid":"FYPO:0003375"}


id: MONDO:0023369
data:
  {"annotated_genes":["SJAG_03843"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87353],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013378"}]},"cv_name":"mondo","definition":"A disease that involves the facial skeleton.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skull disorder","termid":"MONDO:0024654"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03843":null},"genotype_count":0,"is_obsolete":false,"name":"disorder of facial skeleton","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C1290148","MEDGEN:712533"],"synonyms":[{"name":"disease of facial skeleton","type":"exact"},{"name":"disease or disorder of facial skeleton","type":"exact"},{"name":"disorder of facial skeleton","type":"exact"},{"name":"facial skeleton disease","type":"exact"},{"name":"facial skeleton disease or disorder","type":"exact"},{"name":"maxillo-facial disease","type":"exact"},{"name":"maxillofacial anomaly","type":"exact"}],"termid":"MONDO:0023369","terms_by_termid":{"MONDO:0013378":null},"xrefs":{"Monarch":{"xref_id":"0023369"}}}


id: MONDO:0000903
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Myoclonus-dystonia syndrome (MDS) is a rare movement disorder characterized by mild to moderate dystonia along with 'lightning-like' myoclonic jerks.","definition_xrefs":["Orphanet:36899"],"direct_ancestors":[{"relation_name":"is_a","term_name":"combined dystonia","termid":"MONDO:0020065"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"myoclonus-dystonia syndrome","secondary_identifiers":["MESH:C536096","DOID:0090033","NANDO:1200522","GARD:7139","ICD9:333.99","SCTID:439732004"],"synonyms":[{"name":"DYT-SGCE","type":"exact"},{"name":"DYT11","type":"related"},{"name":"Hereditary essential myoclonus","type":"related"},{"name":"alcohol-responsive dystonia","type":"related"},{"name":"dystonia 11","type":"related"},{"name":"dystonia 11, myoclonic","type":"related"},{"name":"dystonia with myoclonus","type":"exact"},{"name":"dystonia, alcohol responsive","type":"related"},{"name":"dystonia, alcohol-responsive","type":"related"},{"name":"dystonia-11, myoclonic","type":"related"},{"name":"hereditary essential myoclonus","type":"exact"},{"name":"myoclonic dystonia","type":"exact"},{"name":"myoclonus, hereditary essential","type":"related"},{"name":"myoclonus-Dystonia","type":"related"},{"name":"myoclonus-dystonia","type":"related"},{"name":"myoclonus-dystonia syndrome","type":"exact"}],"termid":"MONDO:0000903","xrefs":{"Monarch":{"xref_id":"0000903"}}}


id: GO:0044105
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+.","definition_xrefs":["PMID:14736891","RHEA:68100"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"L-xylulose reductase (NADH) activity","secondary_identifiers":["MetaCyc:RXN-11825"],"termid":"GO:0044105"}


