# terms

id: FYPO:0007328
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah","PMID:31833215"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular physical quality phenotype during vegetative growth","termid":"FYPO:0001321"},{"relation_name":"is_a","term_name":"normal cellular physical quality phenotype","termid":"FYPO:0007723"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal number of Rad52 foci during vegetative growth","synonyms":[{"name":"normal number of Rad22 foci","type":"exact"},{"name":"normal number of Rad52 foci during mitotic cell cycle","type":"related"}],"termid":"FYPO:0007328"}


id: PBO:0040311
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP synthase F1 subunit alpha pseudogene 3","termid":"PBO:0040311"}


id: PR:G2TRJ7
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC1834.13 gene.","definition_xrefs":["UniProtKB:G2TRJ7","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein c1834.13 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1834.13","synonyms":[{"name":"Spom972h-SPAC1834.13","type":"exact"}],"termid":"PR:G2TRJ7"}


id: PBO:0062525
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 8 subfamily T member 1 pseudogene","termid":"PBO:0062525"}


id: PR:O13725
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An apolipoprotein A-I-binding protein that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01539","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAD(P)H-hydrate epimerase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC15A10.05c","secondary_identifiers":["UniProtKB:O13725"],"synonyms":[{"name":"NAD(P)HX epimerase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-APOA1BP","type":"exact"},{"name":"meiotically up-regulated gene 182 protein (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O13725"}


id: PBO:0053568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 583","termid":"PBO:0053568"}


id: PBO:0085049
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-essential protein of unknown function","termid":"PBO:0085049"}


id: PBO:0058441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5006","termid":"PBO:0058441"}


id: PBO:0069479
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 746, pseudogene","termid":"PBO:0069479"}


id: PR:O13737
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC16E8.02 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O13737"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized endoplasmic reticulum membrane protein C16E8.02 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC16E8.02","synonyms":[{"name":"Spom972h-SPAC16E8.02","type":"exact"}],"termid":"PR:O13737"}


id: PR:000025003
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mfm1 gene or a 1:1 ortholog thereof.","definition_xrefs":["PRO:MSY"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein","termid":"PR:000000001"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"M-factor precursor mfm1","pombase_gene_id":"SPAPB8E5.05","synonyms":[{"name":"mfm1","type":"exact"}],"termid":"PR:000025003"}


id: PBO:0067824
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 126","termid":"PBO:0067824"}


id: PR:O14119
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A seipin that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR21212:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"seipin homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3A11.04","secondary_identifiers":["UniProtKB:O14119"],"synonyms":[{"name":"Spom972h-BSCL2","type":"exact"}],"termid":"PR:O14119"}


id: PBO:0078059
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha joining 49","termid":"PBO:0078059"}


id: FYPO:0007239
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the old growing cell tip is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:31719163","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to growing cell tip","termid":"FYPO:0003316"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000138","FYPO:0001312","FYPO:0000257","FYPO:0000002"],"is_obsolete":false,"name":"normal protein localization to old growing cell tip","synonyms":[{"name":"normal protein localisation to old growing cell tip","type":"exact"},{"name":"normal protein localization to old growing cell end","type":"exact"},{"name":"normal protein localization to old growing cell tip during mitotic cell cycle","type":"related"},{"name":"normal protein localization to old growing cell tip during vegetative growth","type":"exact"}],"termid":"FYPO:0007239"}


id: GO:0045989
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of striated muscle contraction.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of striated muscle contraction","termid":"GO:0006942"},{"relation_name":"is_a","term_name":"positive regulation of muscle contraction","termid":"GO:0045933"},{"relation_name":"positively_regulates","term_name":"striated muscle contraction","termid":"GO:0006941"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of striated muscle contraction","synonyms":[{"name":"activation of striated muscle contraction","type":"narrow"},{"name":"stimulation of striated muscle contraction","type":"narrow"},{"name":"up regulation of striated muscle contraction","type":"exact"},{"name":"up-regulation of striated muscle contraction","type":"exact"},{"name":"upregulation of striated muscle contraction","type":"exact"}],"termid":"GO:0045989"}


id: FYPO:0007864
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to one or both poles of the meiotic spindle does not occur during the first meiotic nuclear division.","definition_xrefs":["PMID:34346498","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein localization","termid":"FYPO:0001375"},{"relation_name":"is_a","term_name":"abnormal protein localization to meiotic spindle","termid":"FYPO:0006454"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001985","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"abolished protein localization to meiotic spindle pole during meiosis I","synonyms":[{"name":"abolished protein localisation to meiotic spindle pole during meiosis I","type":"exact"},{"name":"abolished protein localisation to spindle pole during meiosis I","type":"exact"},{"name":"abolished protein localization to meiosis I spindle pole","type":"exact"},{"name":"abolished protein localization to spindle pole during first meiotic nuclear division","type":"exact"},{"name":"protein localization to meiotic spindle pole during meiosis I abolished","type":"exact"}],"termid":"FYPO:0007864"}


id: GO:0019211
data:
  {"annotated_genes":["SJAG_00078","SJAG_03793","SJAG_00526","SJAG_04968","SJAG_03681","SJAG_00095","SJAG_03353","SJAG_01142","SJAG_00369","SJAG_04638","SJAG_01270"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[118977],"is_not":false,"summary":null,"term":"GO:0019211"},{"annotations":[76789,74967,79250,73033,93259,118345,98032,115368],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072542"},{"annotations":[76117,72079],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008160"}]},"cv_name":"molecular_function","definition":"Binds to and increases the activity of a phosphatase.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme activator activity","termid":"GO:0008047"},{"relation_name":"is_a","term_name":"phosphatase regulator activity","termid":"GO:0019208"}],"gene_count":11,"genes_by_uniquename":{"SJAG_00078":null,"SJAG_00095":null,"SJAG_00369":null,"SJAG_00526":null,"SJAG_01142":null,"SJAG_01270":null,"SJAG_03353":null,"SJAG_03681":null,"SJAG_03793":null,"SJAG_04638":null,"SJAG_04968":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140677"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0030234"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0030234","GO:0140677","GO:0098772","GO:0003674"],"is_obsolete":false,"name":"phosphatase activator activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0019211","terms_by_termid":{"GO:0008160":null,"GO:0019211":null,"GO:0072542":null}}


id: GO:0008554
data:
  {"annotated_genes":["SJAG_04167"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[73796],"is_not":false,"summary":null,"term":"GO:0008554"}]},"cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism.","definition_xrefs":["PMID:9224683"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sodium ion transmembrane transporter activity","termid":"GO:0015081"},{"relation_name":"is_a","term_name":"P-type ion transporter activity","termid":"GO:0015662"},{"relation_name":"is_a","term_name":"ATPase-coupled monoatomic cation transmembrane transporter activity","termid":"GO:0019829"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04167":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"P-type sodium transporter activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["EC:7.2.2.3"],"synonyms":[{"name":"Na(+)-exporting ATPase activity","type":"broad"},{"name":"Na(+)-transporting ATPase activity","type":"broad"},{"name":"Na+-exporting ATPase activity","type":"broad"},{"name":"Na+-transporting ATPase activity","type":"broad"},{"name":"sodium exporting ATPase activity, phosphorylative mechanism","type":"exact"},{"name":"sodium transmembrane transporter activity, phosphorylative mechanism","type":"exact"},{"name":"sodium transport ATPase activity","type":"broad"},{"name":"sodium-exporting ATPase activity","type":"broad"},{"name":"sodium-exporting ATPase activity, phosphorylative mechanism","type":"exact"},{"name":"sodium-translocating P-type ATPase activity","type":"exact"}],"termid":"GO:0008554","terms_by_termid":{"GO:0008554":null}}


id: FYPO:0004903
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell separation after cytokinesis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Cell separation after cytokinesis RNAs are transcribed from genes whose products are involved in cell separation after cytokinesis.","definition_xrefs":["PomBase:mah","PMID:25530312"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased RNA level during vegetative growth","termid":"FYPO:0001117"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0006551","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"decreased level of cell separation after cytokinesis gene mRNA during vegetative growth","synonyms":[{"name":"decreased cell separation after cytokinesis gene mRNA accumulation during vegetative growth","type":"related"},{"name":"decreased level of cell separation after cytokinesis gene RNA during vegetative growth","type":"exact"},{"name":"decreased level of cell separation after cytokinesis gene mRNA during mitotic cell cycle","type":"related"},{"name":"decreased level of cell separation after cytokinesis gene transcripts during vegetative growth","type":"exact"},{"name":"decreased level of cytokinetic cell separation gene mRNA during vegetative growth","type":"related"},{"name":"reduced level of cell separation after cytokinesis gene mRNA during vegetative growth","type":"exact"}],"termid":"FYPO:0004903"}


id: GO:0002268
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.","definition_xrefs":["GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"follicular dendritic cell activation","termid":"GO:0002266"},{"relation_name":"is_a","term_name":"cell differentiation","termid":"GO:0030154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"follicular dendritic cell differentiation","termid":"GO:0002268"}


id: PBO:0055902
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 25","termid":"PBO:0055902"}


id: PBO:0002113
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DUF887 family protein","termid":"PBO:0002113"}


id: MONDO:0005341
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas.","definition_xrefs":["NCIT:C2921"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin squamous cell carcinoma","termid":"MONDO:0002529"},{"relation_name":"is_a","term_name":"basal cell carcinoma","termid":"MONDO:0020804"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005093"],"is_obsolete":false,"name":"skin basal cell carcinoma","secondary_identifiers":["MEDGEN:1648304","ONCOTREE:BCC","DOID:2513","CSP:2000-2719","HP:0002671","UMLS:C4721806","SCTID:254701007","ICDO:8090/3"],"synonyms":[{"name":"BCC","type":"broad"},{"name":"basal cell cancer","type":"broad"},{"name":"basal cell carcinoma","type":"broad"},{"name":"basal cell carcinoma of skin","type":"exact"},{"name":"basal cell carcinoma of the skin","type":"exact"},{"name":"basal cell epithelioma","type":"exact"},{"name":"basal cell skin carcinoma","type":"exact"},{"name":"basal cell tumor","type":"broad"},{"name":"basal cell tumour","type":"broad"},{"name":"basal cell tumour (morphologic abnormality)","type":"broad"},{"name":"epithelioma basal cell","type":"related"},{"name":"malignant basal cell tumour","type":"broad"},{"name":"malignant basal cell tumour (morphologic abnormality)","type":"broad"},{"name":"skin basal cell cancer","type":"exact"},{"name":"skin basal cell carcinoma","type":"exact"}],"termid":"MONDO:0005341","xrefs":{"Monarch":{"xref_id":"0005341"}}}


id: PBO:0051245
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable (II)-67-1 (pseudogene)","termid":"PBO:0051245"}


id: PBO:0057731
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 1306","termid":"PBO:0057731"}


id: GO:0099557
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.","definition_xrefs":["GOC:dos","PMID:19029886"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trans-synaptic signaling by trans-synaptic complex","termid":"GO:0099545"},{"relation_name":"is_a","term_name":"trans-synaptic signaling, modulating synaptic transmission","termid":"GO:0099550"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission","termid":"GO:0099557"}


id: MONDO:0013806
data:
  {"annotated_genes":["SJAG_00364"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86785],"is_not":false,"summary":null,"term":"MONDO:0013806"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"},{"relation_name":"is_a","term_name":"skin vascular disease","termid":"MONDO:0019293"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00364":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:17413","OMIM:614564","MEDGEN:482833","Orphanet:313846","UMLS:C3281203"],"synonyms":[{"name":"FCTCS","type":"related"},{"name":"cutaneous telangiectasia and cancer syndrome, familial","type":"related"},{"name":"familial cutaneous telangiectasia and oropharyngeal cancer predisposition syndrome","type":"related"},{"name":"familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome","type":"exact"},{"name":"telangiectasia, cutaneous, and cancer syndrome, familial","type":"related"}],"termid":"MONDO:0013806","terms_by_termid":{"MONDO:0013806":null},"xrefs":{"Monarch":{"xref_id":"0013806"}}}


id: MONDO:1012597
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Oculocutaneous albinism that occurs in cattle due to a mutation in the TYR gene.","definition_xrefs":["MONDO:patterns/nonhuman_disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oculocutaneous albinism, non-human animal","termid":"MONDO:1012579"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oculocutaneous albinism, TYR-related, cattle","secondary_identifiers":["OMIA:000202-9913"],"synonyms":[{"name":"coat/skin colour, oculocutaneous albinism type I (OCA1), TYR-related in Bos taurus (taurine cattle)","type":"exact"}],"termid":"MONDO:1012597","xrefs":{"Monarch":{"xref_id":"1012597"}}}


id: MOD:00819
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-glutamic acid residue to L-2-aminobutanoic acid.","definition_xrefs":["ChEBI:35619","DeltaMass:0","RESID:AA0409","PubMed:11740505"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-glutamic acid residue","termid":"MOD:00906"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-2-aminobutanoic acid (Glu)","synonyms":[{"name":"(S)-2-aminobutanoic acid","type":"exact"},{"name":"Abu","type":"exact"},{"name":"L-2-amino-n-butyric acid","type":"exact"},{"name":"L-2-aminobutanoic acid","type":"exact"},{"name":"L-2-aminobutyric acid","type":"exact"},{"name":"L-alpha-amino-n-butyric acid","type":"exact"},{"name":"L-alpha-aminobutyric acid","type":"exact"},{"name":"L-butyrine","type":"exact"},{"name":"alpha-amino-n-butyric acid","type":"exact"},{"name":"alpha-aminobutyric acid","type":"exact"},{"name":"butyrine","type":"exact"},{"name":"dCbxGlu","type":"exact"}],"termid":"MOD:00819"}


id: GO:0006147
data:
  {"annotated_genes":["SJAG_01997"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[68454],"is_not":false,"summary":null,"term":"GO:0006147"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine nucleobase catabolic process","termid":"GO:0006145"},{"relation_name":"is_a","term_name":"guanine metabolic process","termid":"GO:0046098"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01997":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0055086","GO:0008150"],"is_obsolete":false,"name":"guanine catabolic process","references_by_uniquename":{"GO_REF:0000041":null},"synonyms":[{"name":"guanine breakdown","type":"exact"},{"name":"guanine catabolism","type":"exact"},{"name":"guanine degradation","type":"exact"}],"termid":"GO:0006147","terms_by_termid":{"GO:0006147":null}}


id: GO:0046150
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"melanin metabolic process","termid":"GO:0006582"},{"relation_name":"is_a","term_name":"phenol-containing compound catabolic process","termid":"GO:0019336"},{"relation_name":"is_a","term_name":"pigment catabolic process","termid":"GO:0046149"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"melanin catabolic process","synonyms":[{"name":"melanin breakdown","type":"exact"},{"name":"melanin catabolism","type":"exact"},{"name":"melanin degradation","type":"exact"}],"termid":"GO:0046150"}


id: PBO:0049456
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycogenin 1 pseudogene 1","termid":"PBO:0049456"}


id: MONDO:0002866
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pathological conditions in the duodenum region of the small intestine (intestine, small).","definition_xrefs":["MESH:D004378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small intestine disorder","termid":"MONDO:0024635"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"duodenal disorder","secondary_identifiers":["ICD9:537.9","DOID:4072","ICD9:537.89","MEDGEN:8502","SCTID:52182008","UMLS:C0013289"],"synonyms":[{"name":"disease of duodenum","type":"exact"},{"name":"disease or disorder of duodenum","type":"exact"},{"name":"disorder of duodenum","type":"exact"},{"name":"duodenum disease","type":"exact"},{"name":"duodenum disease or disorder","type":"exact"},{"name":"duodenum disorder","type":"exact"}],"termid":"MONDO:0002866","xrefs":{"Monarch":{"xref_id":"0002866"}}}


id: MONDO:0008038
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare genetic disease characterized by cerebellar ataxia, cytopenias and predisposition to bone marrow failure and myeloid leukemia. Neurologic features variably include slowly progressive cerebellar ataxia or balance impairment with cerebellar atrophy and periventricular white matter T2 hyperintensities in brain MRI, horizontal and vertical nystagmus, dysmetria, dysarthria, pyramidal tract signs and reduced nerve conduction velocity. Hematological abnormalities are variable and may be intermittent and include cytopenias of all cell lineages, immunodeficiency, myelodysplasia and acute myeloid leukemia.","definition_xrefs":["Orphanet:2585"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete disorder of medulla oblongata (obsolete MONDO:0015141)","termid":"MONDO:0015141"},{"relation_name":"is_a","term_name":"hereditary cerebellar ataxia","termid":"MONDO:0100310"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"ataxia-pancytopenia syndrome","secondary_identifiers":["MEDGEN:230896","MESH:C563233","SCTID:768556005","OMIM:159550","GARD:3865","NCIT:C176909","UMLS:C1327919","ICD10CM:D61.0"],"synonyms":[{"name":"ATXPC","type":"related"},{"name":"ataxia-pancytopenia syndrome","type":"exact"},{"name":"myelocerebellar disorder","type":"exact"}],"termid":"MONDO:0008038","xrefs":{"Monarch":{"xref_id":"0008038"}}}


id: MONDO:0000078
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A common presentation of craniosynostosis and polysyndactyly.","definition_xrefs":["Wikipedia:Acrocephalosyndactylia"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acrocephalosyndactyly","termid":"MONDO:0019796"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"acrocephalopolysyndactyly","secondary_identifiers":["MEDGEN:673840","SCTID:205260006","UMLS:C0687154"],"synonyms":[{"name":"ACPS","type":"exact"}],"termid":"MONDO:0000078","xrefs":{"Monarch":{"xref_id":"0000078"}}}


id: GO:0061123
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of positive chemotaxis","termid":"GO:0050928"},{"relation_name":"is_a","term_name":"regulation of positive chemotaxis to cAMP","termid":"GO:0061118"},{"relation_name":"negatively_regulates","term_name":"chemotaxis to cAMP","termid":"GO:0043327"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of positive chemotaxis to cAMP","termid":"GO:0061123"}


id: PBO:0027807
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_KT5823","termid":"PBO:0027807"}


id: PBO:0028402
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_respiratory_electron_transport","termid":"PBO:0028402"}


id: PBO:0029865
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-viable_spheroid_vegetative_cell_population_(obsolete_FYPO:0002372)","termid":"PBO:0029865"}


id: PBO:0081573
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 500","termid":"PBO:0081573"}


id: PBO:0066268
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding motif protein Y-linked family 1 member B","termid":"PBO:0066268"}


id: PBO:0018128
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"splicing factor Bis1","termid":"PBO:0018128"}


id: GO:1901330
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inhibition of neuroepithelial cell differentiation","termid":"GO:0002085"},{"relation_name":"is_a","term_name":"regulation of odontoblast differentiation","termid":"GO:1901329"},{"relation_name":"negatively_regulates","term_name":"odontoblast differentiation","termid":"GO:0071895"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of odontoblast differentiation","synonyms":[{"name":"down regulation of odontoblast differentiation","type":"exact"},{"name":"down-regulation of odontoblast differentiation","type":"exact"},{"name":"downregulation of odontoblast differentiation","type":"exact"},{"name":"inhibition of odontoblast differentiation","type":"narrow"}],"termid":"GO:1901330"}


id: SO:0000432
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The U5 segment of the three-prime long terminal repeat.","direct_ancestors":[{"relation_name":"is_a","term_name":"three_prime_LTR_component","termid":"SO:0000849"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U5_three_prime_LTR_region","synonyms":[{"name":"U5 3' long terminal repeat region","type":"exact"},{"name":"U5 three prime LTR region","type":"exact"}],"termid":"SO:0000432"}


id: GO:0031863
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a prostaglandin D2 receptor.","definition_xrefs":["GOC:mah","GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"prostanoid receptor binding","termid":"GO:0031862"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"prostaglandin D2 receptor binding","synonyms":[{"name":"prostaglandin D2 receptor ligand","type":"narrow"},{"name":"prostanoid DP receptor binding","type":"exact"}],"termid":"GO:0031863"}


id: PBO:0050706
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HSPB2-C11orf52 readthrough (NMD candidate)","termid":"PBO:0050706"}


id: FYPO:0003793
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to osmotic stress is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal RNA level during vegetative growth","termid":"FYPO:0001317"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal RNA level during cellular response to osmotic stress","synonyms":[{"name":"normal RNA accumulation during cellular response to osmotic stress","type":"related"},{"name":"normal RNA level during cellular response to osmotic stress during mitotic cell cycle","type":"related"},{"name":"normal RNA level during cellular response to osmotic stress during vegetative growth","type":"exact"},{"name":"normal mRNA level during cellular response to osmotic stress","type":"narrow"},{"name":"normal transcript level during cellular response to osmotic stress","type":"exact"}],"termid":"FYPO:0003793"}


id: MONDO:0016396
data:
  {"annotated_genes":["SJAG_04084","SJAG_04321"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86642],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013853"},{"annotations":[87232],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014485"}]},"cv_name":"mondo","definition":"Pontocerebellar hypoplasia type 1 (PCH1), also known as Norman's disease, is a clinically and genetically heterogeneous group of autosomal recessive disorders with a prenatal onset characterized by diffuse muscular atrophy secondary to pontocerebellar hypoplasia and spinal cord anterior horn cell degeneration resulting in early death.","definition_xrefs":["Orphanet:2254"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental anomaly of metabolic origin","termid":"MONDO:0015327"},{"relation_name":"is_a","term_name":"bulbospinal muscular atrophy","termid":"MONDO:0016113"},{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"},{"relation_name":"is_a","term_name":"pontocerebellar hypoplasia","termid":"MONDO:0020135"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04084":null,"SJAG_04321":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0020022"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0006025","MONDO:0005559","MONDO:0005066","MONDO:0020022"],"is_obsolete":false,"name":"pontocerebellar hypoplasia type 1","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["icd11.foundation:1227773923","UMLS:C5442006","GARD:10704","MEDGEN:1780208","MESH:C548069","SCTID:718610008","DOID:0112322"],"synonyms":[{"name":"MRT32","type":"exact"},{"name":"Norman disease","type":"exact"},{"name":"PCH1","type":"exact"},{"name":"mental retardation, autosomal recessive 32","type":"related"}],"termid":"MONDO:0016396","terms_by_termid":{"MONDO:0013853":null,"MONDO:0014485":null},"xrefs":{"Monarch":{"xref_id":"0016396"}}}


id: GO:0140872
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system.","definition_xrefs":["PMID:20534346","PMID:24161266"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polyketide biosynthetic process","termid":"GO:0030639"},{"relation_name":"is_a","term_name":"ketone biosynthetic process","termid":"GO:0042181"},{"relation_name":"is_a","term_name":"mycotoxin biosynthetic process","termid":"GO:0043386"},{"relation_name":"is_a","term_name":"amide biosynthetic process","termid":"GO:0043604"},{"relation_name":"is_a","term_name":"phenol-containing compound biosynthetic process","termid":"GO:0046189"},{"relation_name":"is_a","term_name":"olefinic compound biosynthetic process","termid":"GO:0120255"},{"relation_name":"is_a","term_name":"ether biosynthetic process","termid":"GO:1901503"},{"relation_name":"is_a","term_name":"tertiary alcohol biosynthetic process","termid":"GO:1902645"},{"relation_name":"is_a","term_name":"secondary alcohol biosynthetic process","termid":"GO:1902653"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"viridicatumtoxin biosynthetic process","secondary_identifiers":["MetaCyc:PWY-7659"],"synonyms":[{"name":"viridicatumtoxin anabolism","type":"exact"},{"name":"viridicatumtoxin biosynthesis","type":"exact"},{"name":"viridicatumtoxin formation","type":"exact"},{"name":"viridicatumtoxin synthesis","type":"exact"}],"termid":"GO:0140872"}


id: FYPO:0006232
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydrogen peroxide.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished protein phosphorylation during vegetative growth","termid":"FYPO:0002033"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0002494","FYPO:0002274","FYPO:0001320"],"is_obsolete":false,"name":"abolished protein phosphorylation during cellular response to hydrogen peroxide","synonyms":[{"name":"abolished protein phosphorylation during cellular response to H2O2","type":"exact"},{"name":"abolished protein phosphorylation during cellular response to hydrogen peroxide during mitotic cell cycle","type":"related"},{"name":"abolished protein phosphorylation during cellular response to hydrogen peroxide during vegetative growth","type":"exact"},{"name":"protein phosphorylation abolished during cellular response to hydrogen peroxide","type":"exact"}],"termid":"FYPO:0006232"}


id: GO:0035673
data:
  {"annotated_genes":["SJAG_05182","SJAG_01660","SJAG_02139","SJAG_01983","SJAG_02602","SJAG_00922","SJAG_03577"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[75982],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015421"},{"annotations":[118748,72195,118749],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071916"},{"annotations":[95860,113518],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034634"},{"annotations":[108353],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1901584"},{"annotations":[72193],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042937"}]},"cv_name":"molecular_function","definition":"Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.","definition_xrefs":["GOC:vw","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amide transmembrane transporter activity","termid":"GO:0042887"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00922":null,"SJAG_01660":null,"SJAG_01983":null,"SJAG_02139":null,"SJAG_02602":null,"SJAG_03577":null,"SJAG_05182":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0022857","GO:0005215"],"is_obsolete":false,"name":"oligopeptide transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["GO:0015198"],"synonyms":[{"name":"oligopeptide transporter activity","type":"related"}],"termid":"GO:0035673","terms_by_termid":{"GO:0015421":null,"GO:0034634":null,"GO:0042937":null,"GO:0071916":null,"GO:1901584":null}}


id: PBO:0005067
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"malic enzyme, malate dehydrogenase (oxaloacetate decarboxylating), Mae2","termid":"PBO:0005067"}


id: PR:Q10271
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- arb2 gene.","definition_xrefs":["UniProtKB:Q10271","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"argonaute-binding protein 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC13G7.07","synonyms":[{"name":"Spom972h-arb2","type":"exact"}],"termid":"PR:Q10271"}


id: FYPO:0004614
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule, is abnormal.","definition_xrefs":["GO:0046785","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein-containing complex assembly","termid":"FYPO:0000447"},{"relation_name":"is_a","term_name":"abnormal microtubule dynamics during vegetative growth","termid":"FYPO:0000901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000054","FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abnormal microtubule polymerization during vegetative growth","synonyms":[{"name":"abnormal microtubule growth","type":"exact"},{"name":"abnormal microtubule polymerisation","type":"exact"},{"name":"abnormal microtubule polymerisation during vegetative growth","type":"exact"},{"name":"abnormal microtubule polymerization during mitotic cell cycle","type":"related"},{"name":"abnormal microtubule rescue","type":"related"}],"termid":"FYPO:0004614"}


id: PBO:0082392
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Beta' regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase","termid":"PBO:0082392"}


id: PBO:0058459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5188","termid":"PBO:0058459"}


id: PBO:0001457
data:
  {"annotation_feature_type":"gene","cv_name":"m_f_g","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone chaperone","termid":"PBO:0001457"}


id: SO:0001084
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The residue at an extremity of the sequence is not the terminal residue.","definition_xrefs":["EBIBS:GAR","UniProt:curation_manual"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polypeptide_sequencing_information","termid":"SO:0001082"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non_terminal_residue","secondary_identifiers":["BS:00072"],"synonyms":[{"name":"non terminal","type":"exact"},{"name":"non_ter","type":"exact"}],"termid":"SO:0001084"}


id: PBO:0013053
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"U2 snRNP-associated protein Sap130","termid":"PBO:0013053"}


id: PBO:0065088
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein kinase cAMP-activated catalytic subunit alpha","termid":"PBO:0065088"}


id: GO:2000732
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of transcription by RNA polymerase I","termid":"GO:0045943"},{"relation_name":"is_a","term_name":"positive regulation of termination of DNA-templated transcription","termid":"GO:0060566"},{"relation_name":"is_a","term_name":"regulation of termination of RNA polymerase I transcription","termid":"GO:2000730"},{"relation_name":"positively_regulates","term_name":"termination of RNA polymerase I transcription","termid":"GO:0006363"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0006355"},{"rel_name":"positively_regulates","termid":"GO:0006351"}],"interesting_parent_ids":["GO:0008150","GO:0006351","GO:0010467","GO:0006355"],"is_obsolete":false,"name":"positive regulation of termination of RNA polymerase I transcription","synonyms":[{"name":"positive regulation of RNA polymerase I transcription termination","type":"exact"},{"name":"positive regulation of transcription termination from Pol I promoter","type":"exact"},{"name":"positive regulation of transcription termination from RNA polymerase I promoter","type":"exact"}],"termid":"GO:2000732"}


id: MONDO:0010996
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary hemorrhagic telangiectasia","termid":"MONDO:0019180"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426"],"is_obsolete":false,"name":"hereditary hemorrhagic telangiectasia type 3","secondary_identifiers":["GARD:9902","UMLS:C1832774","MEDGEN:371403","MESH:C537140","OMIM:601101"],"synonyms":[{"name":"HHT3","type":"related"},{"name":"ORW3","type":"related"},{"name":"Osler Weber Rendu syndrome type 3","type":"related"},{"name":"telangiectasia hereditary hemorrhagic type 3","type":"related"},{"name":"telangiectasia, hereditary hemorrhagic, type 3","type":"related"}],"termid":"MONDO:0010996","xrefs":{"Monarch":{"xref_id":"0010996"}}}


id: PBO:0075965
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"StAR related lipid transfer domain containing 6","termid":"PBO:0075965"}


id: GO:0044681
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.","definition_xrefs":["PMID:10940029","GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"sulfopyruvate decarboxylase complex","termid":"GO:0044681"}


id: FYPO:0005288
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) occurs to a lower extent than normal. Specific genes that are normally not transcribed in the presence of glucose are transcribed in the mutant.","definition_xrefs":["GO:0045014","PMID:18430926","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal negative regulation of transcription by glucose","termid":"FYPO:0000044"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0006551","FYPO:0000298","FYPO:0001320","FYPO:0001985","FYPO:0000002"],"is_obsolete":false,"name":"decreased negative regulation of transcription by glucose","synonyms":[{"name":"decreased glucose repression","type":"exact"},{"name":"decreased glucose repression during vegetative growth","type":"exact"},{"name":"decreased negative regulation of transcription by glucose during mitotic cell cycle","type":"related"},{"name":"decreased negative regulation of transcription by glucose during vegetative growth","type":"exact"},{"name":"glucose repression defects","type":"related"},{"name":"glucose-insensitive transcription","type":"related"},{"name":"increased transcription of glucose starvation gene during vegetative growth","type":"related"}],"termid":"FYPO:0005288"}


id: MONDO:0030046
data:
  {"annotated_genes":["SJAG_02584"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[85746],"is_not":false,"summary":null,"term":"MONDO:0030046"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Mendelian neurodevelopmental disorder","termid":"MONDO:0100500"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02584":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092"],"is_obsolete":false,"name":"neurodevelopmental disorder and structural brain anomalies with or without seizures and spasticity","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1711516","OMIM:618890","UMLS:C5394423"],"synonyms":[{"name":"NEDBASS","type":"exact"},{"name":"NEURODEVELOPMENTAL DISORDER AND STRUCTURAL BRAIN ANOMALIES WITH OR WITHOUT SEIZURES AND SPASTICITY","type":"exact"},{"name":"neurodevelopmental disorder and structural brain anomalies with or without seizures and spasticity","type":"exact"}],"termid":"MONDO:0030046","terms_by_termid":{"MONDO:0030046":null},"xrefs":{"Monarch":{"xref_id":"0030046"}}}


id: PBO:0052821
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratin 87, pseudogene","termid":"PBO:0052821"}


id: GO:0002410
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The movement of a plasmacytoid dendritic cell in response to an external stimulus.","definition_xrefs":["PMID:15814331","GOC:add","PMID:15159375"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dendritic cell chemotaxis","termid":"GO:0002407"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"plasmacytoid dendritic cell chemotaxis","termid":"GO:0002410"}


id: FYPO:0007655
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at one or more specific sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes.","definition_xrefs":["PomBase:mah","PMID:33511417"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nucleosome positioning","termid":"FYPO:0000853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000641","FYPO:0005447","FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"increased nucleosome occupancy","synonyms":[{"name":"increased nucleosome occupancy during mitotic cell cycle","type":"related"},{"name":"increased nucleosome occupancy during vegetative growth","type":"exact"}],"termid":"FYPO:0007655"}


id: PBO:0072291
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S24 pseudogene 9","termid":"PBO:0072291"}


id: PBO:0088047
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ubiquitin-conjugating enzyme variant; involved in error-free postreplication repair; forms a heteromeric complex with Ubc13p, an active ubiquitin-conjugating enzyme; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p; protein abundance increases in response to DNA replication stress","termid":"PBO:0088047"}


id: FYPO:0002681
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal when the cell is subject to nitrogen starvation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein phosphorylation","termid":"FYPO:0002680"},{"relation_name":"is_a","term_name":"abnormal protein phosphorylation during nitrogen starvation","termid":"FYPO:0005033"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0002494","FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"increased protein phosphorylation during nitrogen starvation","synonyms":[{"name":"increased protein phosphorylation during cellular response to nitrogen starvation","type":"exact"},{"name":"increased protein phosphorylation during nitrogen depletion","type":"exact"},{"name":"increased protein phosphorylation during nitrogen deprivation","type":"exact"}],"termid":"FYPO:0002681"}


id: PBO:0069137
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 388, pseudogene","termid":"PBO:0069137"}


id: MONDO:0019972
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"arteriovenous hemangioma/malformation","termid":"MONDO:0001256"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dural sinus malformation","secondary_identifiers":["icd11.foundation:454640405","GARD:19368","MEDGEN:824993","Orphanet:97339","UMLS:C3839148"],"synonyms":[{"name":"cranial dural arteriovenous fistula","type":"exact"},{"name":"cranial dural arteriovenous malformations","type":"exact"}],"termid":"MONDO:0019972","xrefs":{"Monarch":{"xref_id":"0019972"}}}


id: PBO:0079752
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uridine-cytidine kinase 1 like 1","termid":"PBO:0079752"}


id: GO:1900928
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of L-threonine import into cell.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of organic acid transport","termid":"GO:0032892"},{"relation_name":"is_a","term_name":"positive regulation of transmembrane transport","termid":"GO:0034764"},{"relation_name":"is_a","term_name":"positive regulation of amino acid transport","termid":"GO:0051957"},{"relation_name":"is_a","term_name":"regulation of L-threonine import across plasma membrane","termid":"GO:1900926"},{"relation_name":"positively_regulates","term_name":"L-threonine import across plasma membrane","termid":"GO:1903807"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0006810"},{"rel_name":"positively_regulates","termid":"GO:0055085"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0055085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0055085","GO:0006810"],"is_obsolete":false,"name":"positive regulation of L-threonine import across plasma membrane","synonyms":[{"name":"activation of L-threonine import","type":"narrow"},{"name":"activation of L-threonine uptake","type":"narrow"},{"name":"positive regulation of L-threonine import","type":"broad"},{"name":"positive regulation of L-threonine uptake","type":"related"},{"name":"up regulation of L-threonine import","type":"exact"},{"name":"up regulation of L-threonine uptake","type":"related"},{"name":"up-regulation of L-threonine import","type":"exact"},{"name":"up-regulation of L-threonine uptake","type":"related"},{"name":"upregulation of L-threonine import","type":"exact"},{"name":"upregulation of L-threonine uptake","type":"related"}],"termid":"GO:1900928"}


id: GO:0070142
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Evagination of a membrane to form a synaptic vesicle.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle budding from membrane","termid":"GO:0006900"},{"relation_name":"part_of","term_name":"synaptic vesicle transport","termid":"GO:0048489"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0016192"}],"interesting_parent_ids":["GO:0006810","GO:0061024","GO:0016192","GO:0008150"],"is_obsolete":false,"name":"synaptic vesicle budding","termid":"GO:0070142"}


id: PBO:0090855
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uracil phosphoribosyltransferase Uck2","termid":"PBO:0090855"}


id: PBO:0069844
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1130, pseudogene","termid":"PBO:0069844"}


id: GO:0010825
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of centrosome duplication","termid":"GO:0010824"},{"relation_name":"is_a","term_name":"positive regulation of cell cycle process","termid":"GO:0090068"},{"relation_name":"positively_regulates","term_name":"centrosome duplication","termid":"GO:0051298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"positively_regulates","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"positive regulation of centrosome duplication","termid":"GO:0010825"}


id: GO:0047459
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH4.","definition_xrefs":["RHEA:10056","EC:4.3.1.14"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ammonia-lyase activity","termid":"GO:0016841"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016829","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"3-aminobutyryl-CoA ammonia-lyase activity","secondary_identifiers":["MetaCyc:4.3.1.14-RXN","KEGG_REACTION:R03030"],"synonyms":[{"name":"L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)","type":"related"},{"name":"L-3-aminobutyryl-CoA ammonia-lyase activity","type":"related"},{"name":"L-3-aminobutyryl-CoA deaminase activity","type":"related"}],"termid":"GO:0047459"}


id: PR:Q09811
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- rqh1 gene.","definition_xrefs":["UniProtKB:Q09811","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent DNA helicase hus2/rqh1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC2G11.12","synonyms":[{"name":"Spom972h-rqh1","type":"exact"}],"termid":"PR:Q09811"}


id: PBO:0059609
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ATP6 pseudogene 21","termid":"PBO:0059609"}


id: PBO:0086458
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; null mutant exhibits longer telomeres, altered Ty mobility, decreased resistance to rapamycin and wortmannin; induced in response to hydrostatic pressure; not an essential gene; YBR284W has a paralog, YJL070C, that arose from the whole genome duplication","termid":"PBO:0086458"}


id: PBO:0053276
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leukocyte immunoglobulin like receptor B2","termid":"PBO:0053276"}


id: PBO:0073422
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"seizure related 6 homolog like 2","termid":"PBO:0073422"}


id: GO:0018404
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.","definition_xrefs":["RESID:AA0210"],"gene_count":0,"genotype_count":0,"name":"obsolete protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine (obsolete GO:0018404)","synonyms":[{"name":"protein-heparan sulphate linkage via heparan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine","type":"exact"}],"termid":"GO:0018404"}


id: PBO:0049284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutathione S-transferase alpha 3","termid":"PBO:0049284"}


id: PBO:0078738
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA methyltransferase 1 like","termid":"PBO:0078738"}


id: GO:0120309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.","definition_xrefs":["PMID:18820079","PMID:22623724","PMID:11877446","PMID:26272611","GOC:ach","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular component organization","termid":"GO:0016043"},{"relation_name":"part_of","term_name":"cilium organization","termid":"GO:0044782"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cilium attachment to cell body","synonyms":[{"name":"cilial attachment to cell body","type":"exact"},{"name":"ciliary attachment to cell body","type":"exact"},{"name":"flagellar attachment to cell body","type":"exact"},{"name":"flagellum attachment to cell body","type":"exact"}],"termid":"GO:0120309"}


id: PBO:0087699
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR)","termid":"PBO:0087699"}


id: PATO:0010000
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in the bearer by virtue of the bearer consisting of a single, maximally connected structure.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"structure","termid":"PATO:0000141"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"maximally connected","termid":"PATO:0010000"}


id: GO:0141214
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of phospholipase C/protein kinase C signal transduction.","definition_xrefs":["PMID:32255775","PMID:24008408"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of intracellular signal transduction","termid":"GO:1902533"},{"relation_name":"positively_regulates","term_name":"phospholipase C/protein kinase C signal transduction","termid":"GO:0141212"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"positive regulation of phospholipase C/protein kinase C signal transduction","synonyms":[{"name":"positive regulation of PLC/PKC signal transduction","type":"exact"}],"termid":"GO:0141214"}


id: GO:0030912
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to water","termid":"GO:0009415"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to deep water","termid":"GO:0030912"}


id: GO:0002693
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate, or extent of cellular extravasation.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of leukocyte migration","termid":"GO:0002687"},{"relation_name":"is_a","term_name":"regulation of cellular extravasation","termid":"GO:0002691"},{"relation_name":"positively_regulates","term_name":"cellular extravasation","termid":"GO:0045123"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of cellular extravasation","synonyms":[{"name":"activation of cellular extravasation","type":"narrow"},{"name":"stimulation of cellular extravasation","type":"narrow"},{"name":"up regulation of cellular extravasation","type":"exact"},{"name":"up-regulation of cellular extravasation","type":"exact"},{"name":"upregulation of cellular extravasation","type":"exact"}],"termid":"GO:0002693"}


id: PBO:0046106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eukaryotic translation initiation factor 4B pseudogene 9","termid":"PBO:0046106"}


id: GO:0033685
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of gonadotropin secretion","termid":"GO:0032277"},{"relation_name":"is_a","term_name":"regulation of luteinizing hormone secretion","termid":"GO:0033684"},{"relation_name":"negatively_regulates","term_name":"luteinizing hormone secretion","termid":"GO:0032275"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of luteinizing hormone secretion","synonyms":[{"name":"down regulation of luteinizing hormone secretion","type":"exact"},{"name":"down-regulation of luteinizing hormone secretion","type":"exact"},{"name":"downregulation of luteinizing hormone secretion","type":"exact"},{"name":"inhibition of luteinizing hormone secretion","type":"narrow"}],"termid":"GO:0033685"}


id: PBO:0088876
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphopantothenate-cysteine ligase Cab2","termid":"PBO:0088876"}


id: GO:0045561
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of TRAIL receptor 1 biosynthetic process (obsolete GO:0045561)","synonyms":[{"name":"regulation of TRAIL receptor 1 anabolism","type":"exact"},{"name":"regulation of TRAIL receptor 1 biosynthesis","type":"exact"},{"name":"regulation of TRAIL receptor 1 formation","type":"exact"},{"name":"regulation of TRAIL receptor 1 synthesis","type":"exact"}],"termid":"GO:0045561"}


id: GO:0052515
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by organism of symbiont innate immunity (obsolete GO:0052515)","synonyms":[{"name":"positive regulation by organism of symbiont innate immunity","type":"exact"},{"name":"positive regulation of symbiont innate immune response","type":"exact"}],"termid":"GO:0052515"}


id: MONDO:0016730
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A well differentiated, slow growing neuroepithelial neoplasm composed of neoplastic, mature ganglion cells.","definition_xrefs":["NCIT:C6934"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mixed neuronal-glial tumor","termid":"MONDO:0016729"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gangliocytoma","secondary_identifiers":["GARD:10638","ONCOTREE:GNC","Orphanet:251937","MESH:D005729","NANDO:2200097","SCTID:116371000119107","UMLS:C5779630","ICDO:9492/0","MEDGEN:1830324","DOID:2426"],"synonyms":[{"name":"GNC","type":"related"}],"termid":"MONDO:0016730","xrefs":{"Monarch":{"xref_id":"0016730"}}}


id: MOD:01039
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"OBSOLETE because redundant and identical to MOD:00036. Remap to MOD:00036.","definition_xrefs":["PubMed:18688235"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE MOD:01039 hydroxy aspartyl (obsolete MOD:01039)","termid":"MOD:01039"}


id: PBO:0064293
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"perilipin 1","termid":"PBO:0064293"}


id: FYPO:0004339
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to hydrogen peroxide.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to nucleus during vegetative growth","termid":"FYPO:0001514"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000138","FYPO:0005447","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein localization to nucleus during cellular response to hydrogen peroxide","synonyms":[{"name":"decreased protein localisation to nucleus during cellular response to hydrogen peroxide","type":"exact"},{"name":"decreased protein localization to nucleus during cellular response to H2O2","type":"exact"},{"name":"decreased protein localization to nucleus during cellular response to hydrogen peroxide during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to nucleus during cellular response to hydrogen peroxide during vegetative growth","type":"exact"},{"name":"reduced protein localization to nucleus during cellular response to hydrogen peroxide","type":"exact"}],"termid":"FYPO:0004339"}


id: PBO:0001601
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3.2.1.1","termid":"PBO:0001601"}


id: MONDO:0019450
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Lissencephaly with cerebellar hypoplasia (LCH) is a variant form of lissencephaly and involves a heterogeneous group of cortical malformations without severe congenital microcephaly (>-3 SD). LCH is characterized by cerebellar underdevelopment ranging from vermian hypoplasia to total aplasia with classical or cobblestone lissencephaly. The phenotypic features of LCH include small head circumference (between -2 and -3 standard deviations (SD) forage) at birth and postnatally, moderate to severe intellectual disability, hypotonia and spasticity. Seizures are often observed and infantile spasms have been reported in some rare cases. LCH has been classified into six subgroups according to neuroradiographic properties and are classified LCH type A to F.","definition_xrefs":["Orphanet:86823"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lissencephaly spectrum disorders","termid":"MONDO:0018838"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"lissencephaly with cerebellar hypoplasia","secondary_identifiers":["SCTID:715817007","GARD:19068","icd11.foundation:649858830","UMLS:C4274995","MEDGEN:905529"],"synonyms":[{"name":"LCH","type":"exact"}],"termid":"MONDO:0019450","xrefs":{"Monarch":{"xref_id":"0019450"}}}


id: PBO:0058971
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"modulator of VRAC current 1","termid":"PBO:0058971"}


id: MONDO:0800306
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Lafora disease in which the cause of the disease is a variation in the NHLRC1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Lafora disease","termid":"MONDO:0009697"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0037792","MONDO:0005027"],"is_obsolete":false,"name":"myoclonic epilepsy of Lafora 2","secondary_identifiers":["MEDGEN:340621","UMLS:C1850764","OMIM:620681"],"synonyms":[{"name":"EPM2B","type":"exact"},{"name":"Lafora disease 2","type":"exact"},{"name":"MELF2","type":"exact"},{"name":"epilepsy, progressive myoclonic, 2B","type":"exact"},{"name":"myoclonic epilepsy of Lafora 2","type":"exact"}],"termid":"MONDO:0800306","xrefs":{"Monarch":{"xref_id":"0800306"}}}


id: FYPO:0003015
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during a cellular response to salt stress. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vegetative cell lysis","termid":"FYPO:0000647"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000004"}],"interesting_parent_ids":["FYPO:0000004","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"cell lysis during cellular response to salt stress","synonyms":[{"name":"cell lysis during cellular response to salt stress during mitotic cell cycle","type":"related"},{"name":"cell lysis during cellular response to salt stress during vegetative growth","type":"exact"},{"name":"cytolysis during cellular response to salt stress","type":"exact"},{"name":"inviable, lysed cell during cellular response to salt stress","type":"exact"},{"name":"lysed cell in response to salt stress","type":"exact"}],"termid":"FYPO:0003015"}


id: GO:0002208
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.","definition_xrefs":["GOC:add","ISBN:0781735149","PMID:14991701"],"direct_ancestors":[{"relation_name":"is_a","term_name":"somatic diversification of immunoglobulins","termid":"GO:0016445"},{"relation_name":"part_of","term_name":"immunoglobulin production involved in immunoglobulin-mediated immune response","termid":"GO:0002381"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"somatic diversification of immunoglobulins involved in immune response","synonyms":[{"name":"somatic diversification of antibodies during immune response","type":"related"},{"name":"somatic diversification of immunoglobulins during immune response","type":"related"}],"termid":"GO:0002208"}


id: GO:0051268
data:
  {"annotated_genes":["SJAG_01869"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[92144],"is_not":false,"summary":null,"term":"GO:0051268"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.","definition_xrefs":["GOC:ai","PMID:15564669"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors","termid":"GO:0016903"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01869":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"alpha-keto amide reductase activity","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0051268","terms_by_termid":{"GO:0051268":null}}


id: MONDO:0014110
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the MIP gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset non-syndromic cataract","termid":"MONDO:0011060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"cataract 15 multiple types","secondary_identifiers":["MEDGEN:815331","DOID:0110251","OMIM:615274","UMLS:C3809001"],"synonyms":[{"name":"CTRCT15","type":"exact"},{"name":"MIP early-onset non-syndromic cataract","type":"exact"},{"name":"cataract 15, multiple types","type":"related"},{"name":"early-onset non-syndromic cataract caused by mutation in MIP","type":"exact"}],"termid":"MONDO:0014110","xrefs":{"Monarch":{"xref_id":"0014110"}}}


id: GO:0040017
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of locomotion","termid":"GO:0040012"},{"relation_name":"is_a","term_name":"positive regulation of biological process","termid":"GO:0048518"},{"relation_name":"positively_regulates","term_name":"locomotion","termid":"GO:0040011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of locomotion","synonyms":[{"name":"activation of locomotion","type":"narrow"},{"name":"stimulation of locomotion","type":"narrow"},{"name":"up regulation of locomotion","type":"exact"},{"name":"up-regulation of locomotion","type":"exact"},{"name":"upregulation of locomotion","type":"exact"}],"termid":"GO:0040017"}


id: PBO:0031378
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_meiosis","termid":"PBO:0031378"}


id: MONDO:0100320
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A SARS-CoV-2-related disease that is caused by infection by SARS-CoV-2, and manifests after the original primary infection.","definition_xrefs":["PMID:32201335"],"direct_ancestors":[{"relation_name":"is_a","term_name":"post-viral disorder","termid":"MONDO:0021674"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"post-COVID-19 disorder","termid":"MONDO:0100320","xrefs":{"Monarch":{"xref_id":"0100320"}}}


id: PBO:0056557
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"minichromosome maintenance complex component 5","termid":"PBO:0056557"}


id: PBO:0031853
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_hydrogen_sulfide_biosynthesis","termid":"PBO:0031853"}


id: PBO:0070820
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L12 pseudogene 50","termid":"PBO:0070820"}


id: MOD:01741
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively replaces an O3-hydrogen atom of a serine residue with the Proteome Sciences TMT6plex-128 reporter+balance group.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"TMT6plex reporter+balance reagent O-acylated residue","termid":"MOD:01719"},{"relation_name":"is_a","term_name":"TMT6plex-128 reporter+balance reagent acylated residue","termid":"MOD:01736"},{"relation_name":"is_a","term_name":"O3-acylated L-serine","termid":"MOD:02003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TMT6plex-128 reporter+balance reagent O3-acylated serine","synonyms":[{"name":"3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoyl","type":"exact"},{"name":"Sixplex Tandem Mass Tag(TM)","type":"related"},{"name":"TMT6plex","type":"related"}],"termid":"MOD:01741"}


id: GO:0090682
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A G protein-coupled receptor activity that is responsible for the sense of bitter taste.","definition_xrefs":["GOC:tb","GOC:hat"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bitter taste receptor activity","termid":"GO:0033038"},{"relation_name":"is_a","term_name":"GPCR taste receptor activity","termid":"GO:0090681"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0038023","GO:0003674"],"is_obsolete":false,"name":"GPCR bitter taste receptor activity","synonyms":[{"name":"G protein-coupled receptor bitter taste receptor activity","type":"exact"},{"name":"G-protein coupled receptor bitter taste receptor activity","type":"exact"}],"termid":"GO:0090682"}


id: PR:Q09780
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A mevalonate kinase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00072","PANTHER:PTHR10457:SF4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mevalonate kinase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC13G6.11c","secondary_identifiers":["UniProtKB:Q09780"],"synonyms":[{"name":"MK (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-MVK","type":"exact"}],"termid":"PR:Q09780"}


id: GO:0034865
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete 2,4,4-trimethylpentanoate-CoA ligase activity (obsolete GO:0034865)","termid":"GO:0034865"}


id: PBO:0038985
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adrenoceptor alpha 2B","termid":"PBO:0038985"}


id: PBO:0109090
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sperm microtubule inner protein 4","termid":"PBO:0109090"}


id: GO:0019019
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.","definition_xrefs":["ISBN:0121585336"],"gene_count":0,"genotype_count":0,"name":"obsolete tripartite viral genome (obsolete GO:0019019)","termid":"GO:0019019"}


id: GO:0035308
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.","definition_xrefs":["GOC:bf"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of protein dephosphorylation (obsolete GO:0035308)","synonyms":[{"name":"down regulation of protein amino acid dephosphorylation","type":"exact"},{"name":"down-regulation of protein amino acid dephosphorylation","type":"exact"},{"name":"downregulation of protein amino acid dephosphorylation","type":"exact"},{"name":"inhibition of protein amino acid dephosphorylation","type":"narrow"},{"name":"negative regulation of protein amino acid dephosphorylation","type":"exact"}],"termid":"GO:0035308"}


id: PBO:0049156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRAM domain containing 2A","termid":"PBO:0049156"}


id: PBO:0060994
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nescient helix-loop-helix 1","termid":"PBO:0060994"}


id: MONDO:0018445
data:
  {"annotated_genes":["SJAG_03689"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86594],"is_not":false,"summary":null,"term":"MONDO:0018445"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"overgrowth syndrome","termid":"MONDO:0019716"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03689":null},"genotype_count":0,"is_obsolete":false,"name":"global developmental delay - lung cysts - overgrowth - Wilms tumor syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1648360","OMIM:618272","Orphanet:404476","GARD:17676","UMLS:C4748924"],"synonyms":[{"name":"GLOW","type":"exact"},{"name":"GLOW syndrome, somatic mosaic","type":"exact"},{"name":"global developmental delay, lung cysts, overgrowth, and wilms tumor","type":"exact"},{"name":"global developmental delay, lung cysts, overgrowth, and wilms tumour","type":"exact"},{"name":"glow syndrome","type":"exact"}],"termid":"MONDO:0018445","terms_by_termid":{"MONDO:0018445":null},"xrefs":{"Monarch":{"xref_id":"0018445"}}}


id: PBO:0061524
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"N-ethylmaleimide-sensitive factor pseudogene 1","termid":"PBO:0061524"}


id: MONDO:0018977
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Polyneuropathy associated with IgM monoclonal gammapathy (MG) with anti-MAG (myelin-associated-glycoprotein) activity is a demyelinating polyneuropathy characterized clinically by sensory ataxia, tremor, paresthesia, and impaired gait.","definition_xrefs":["Orphanet:639"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acquired peripheral neuropathy","termid":"MONDO:0015923"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG","secondary_identifiers":["GARD:13173","MEDGEN:1434346","UMLS:C1736154"],"synonyms":[{"name":"anti-MAG neuropathy","type":"exact"},{"name":"neuropathy associated with monoclonal IgM antibodies to myelin-associated glycoprotein","type":"exact"}],"termid":"MONDO:0018977","xrefs":{"Monarch":{"xref_id":"0018977"}}}


id: MONDO:0015422
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Orofaciodigital syndrome type 13 is a rare subtype of orofaciodigital syndrome, with sporadic occurrence, characterized by cardiac (mitral and tricuspid valve dysplasia) and neuropsychiatric manifestations (epilepsy, depression), in addition to oral, facial and digital malformations (lingual hamartomas, cleft lip, and brachydactyly, clinodactyly, syndactyly of hands and feet). Leukoaraiosis, on brain MRI examination, is also associated.","definition_xrefs":["Orphanet:141330"],"gene_count":0,"genotype_count":0,"name":"obsolete orofaciodigital syndrome type 13 (obsolete MONDO:0015422)","secondary_identifiers":["UMLS:C2932680","GARD:10694","SCTID:763835004","MEDGEN:420203","MESH:C548035"],"synonyms":[{"name":"Degner syndrome","type":"exact"},{"name":"OFD syndrome 13","type":"related"},{"name":"OFD13","type":"exact"},{"name":"OFDS 13","type":"related"},{"name":"oral facial digital syndrome 13","type":"related"},{"name":"oral facial digital syndrome type 13","type":"related"},{"name":"oral-facial-digital syndrome 13","type":"related"},{"name":"oral-facial-digital syndrome XIII","type":"related"},{"name":"oral-facial-digital syndrome type 13","type":"exact"},{"name":"orofaciodigital syndrome 13","type":"related"},{"name":"orofaciodigital syndrome XIII","type":"related"}],"termid":"MONDO:0015422","xrefs":{"Monarch":{"xref_id":"0015422"}}}


id: SO:0002073
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A position or feature within a sequence that is identical to the comparable position or feature of a specified reference sequence.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sequence_comparison","termid":"SO:0002072"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"no_sequence_alteration","synonyms":[{"name":"no sequence alteration","type":"exact"}],"termid":"SO:0002073"}


id: PBO:0073404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SET pseudogene 7","termid":"PBO:0073404"}


id: MONDO:0016532
data:
  {"annotated_genes":["SJAG_01653","SJAG_04038","SJAG_02384","SJAG_02848"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86284,86285],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014150"},{"annotations":[85602,85601],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014598"}]},"cv_name":"mondo","definition":"Lennox-Gastaut syndrome (LGS) belongs to the group of severe childhood epileptic encephalopathies.","definition_xrefs":["Orphanet:2382"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"},{"relation_name":"is_a","term_name":"childhood-onset epilepsy syndrome with developmental and/or epileptic encephalopathy","termid":"MONDO:0800500"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01653":null,"SJAG_02384":null,"SJAG_02848":null,"SJAG_04038":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"},{"rel_name":"is_a","termid":"MONDO:0700092"}],"interesting_parent_ids":["MONDO:0700092","MONDO:0005027"],"is_obsolete":false,"name":"Lennox-Gastaut syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NORD:1358","UMLS:C0238111","MEDGEN:116044","NANDO:2200879","MESH:D065768","SCTID:230418006","GARD:9912","MedDRA:10048816","icd11.foundation:651135242","NANDO:1200591","DOID:0050561","OMIM:606369","NCIT:C84816"],"synonyms":[{"name":"LGS","type":"exact"},{"name":"Lennox syndrome","type":"exact"},{"name":"encephalopathy of childhood","type":"related"},{"name":"epileptic encephalopathy Lennox-Gastaut type","type":"related"},{"name":"macrocephaly and epileptic encephalopathy","type":"related"}],"termid":"MONDO:0016532","terms_by_termid":{"MONDO:0014150":null,"MONDO:0014598":null},"xrefs":{"Monarch":{"xref_id":"0016532"}}}


id: PR:O74365
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- sol1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74365"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SWI/SNF chromatin-remodeling complex subunit sol1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC30B4.04c","synonyms":[{"name":"SWI/SNF complex subunit sol1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-sol1","type":"exact"},{"name":"switch one-like protein (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"transcription regulatory protein sol1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O74365"}


id: PBO:0108704
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ArfGAP, GTPase activating protein for Arf6, Ucp3","termid":"PBO:0108704"}


id: PR:O94453
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A ubiquinone biosynthesis protein COQ4, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00361","PRO:DNx","PANTHER:PTHR12922:SF5"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquinone biosynthesis protein coq4, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1687.12c","secondary_identifiers":["UniProtKB:O94453"],"synonyms":[{"name":"Spom972h-COQ4","type":"exact"},{"name":"coenzyme Q biosynthesis protein 4 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94453"}


id: PBO:0111768
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SNARE","termid":"PBO:0111768"}


id: PBO:0074005
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 25 member 5 pseudogene 6","termid":"PBO:0074005"}


id: GO:0009607
data:
  {"annotated_genes":["SJAG_01837","SJAG_01805","SJAG_04183","SJAG_04332","SJAG_03048","SJAG_00082","SJAG_04140"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117068,102722,90324,111578,94135],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140429"},{"annotations":[104500],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072429"},{"annotations":[102733],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072441"},{"annotations":[102734],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990820"},{"annotations":[102735,94879],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0072435"}]},"cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.","definition_xrefs":["GOC:hb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to stimulus","termid":"GO:0050896"}],"gene_count":7,"genes_by_uniquename":{"SJAG_00082":null,"SJAG_01805":null,"SJAG_01837":null,"SJAG_03048":null,"SJAG_04140":null,"SJAG_04183":null,"SJAG_04332":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to biotic stimulus","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"response to biotic stress","type":"narrow"}],"termid":"GO:0009607","terms_by_termid":{"GO:0072429":null,"GO:0072435":null,"GO:0072441":null,"GO:0140429":null,"GO:1990820":null}}


id: GO:0102833
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + alpha-D-galactosyl-(1->3)-1D-myo-inositol = D-galactosylononitol + myo-inositol.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity (obsolete GO:0102833)","termid":"GO:0102833"}


id: GO:0072675
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.","definition_xrefs":["CL:0000092","CL:0000779","GOC:BHF","GOC:mah","PMID:12713016"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syncytium formation by plasma membrane fusion","termid":"GO:0000768"},{"relation_name":"part_of","term_name":"multinuclear osteoclast differentiation","termid":"GO:0072674"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"osteoclast fusion","termid":"GO:0072675"}


id: PBO:0059148
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"myeloperoxidase","termid":"PBO:0059148"}


id: MONDO:0030986
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"blistering, acantholytic, of oral and laryngeal mucosa","secondary_identifiers":["OMIM:619226","UMLS:C5543184","MEDGEN:1785588"],"synonyms":[{"name":"ABOLM","type":"exact"}],"termid":"MONDO:0030986","xrefs":{"Monarch":{"xref_id":"0030986"}}}


id: PBO:0083979
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Glucosyl hydrolase required for beta-1,6-glucan biosynthesis; type II integral membrane protein that localizes to ER, plasma membrane, sites of polarized growth and secretory vesicles; functionally redundant with Skn1p; KRE6 has a paralog, SKN1, that arose from the whole genome duplication","termid":"PBO:0083979"}


id: PBO:0072030
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPS10-NUDT3 readthrough","termid":"PBO:0072030"}


id: PBO:0055348
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2777","termid":"PBO:0055348"}


id: MONDO:0003724
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Breast fibrocystic change characterized by the absence of epithelial cell hyperplasia.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"breast fibrocystic disease","termid":"MONDO:0005219"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"non-proliferative fibrocystic change of the breast","secondary_identifiers":["NCIT:C6943","UMLS:C1332628","MEDGEN:231966","DOID:5997"],"synonyms":[{"name":"breast fibrocystic change, non-proliferative type","type":"exact"},{"name":"non-proliferative fibrocystic change","type":"exact"},{"name":"non-proliferative fibrocystic change of breast","type":"exact"}],"termid":"MONDO:0003724","xrefs":{"Monarch":{"xref_id":"0003724"}}}


id: PBO:0060454
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NAGPA antisense RNA 1","termid":"PBO:0060454"}


id: MONDO:0015236
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital abnormalities of the aortic arch result from aberrant development of one or more components of the embyronic pharangeal arch system. Any component of this system can regress or persist abnormally, resulting in an extensive array of aortic arch anomalies. Clinically, they are classified by those that cause (or are likely to cause) physiolgogical abnormalities and those that do not. Physiologic abnormalities include tracheobronchial compression, esophageeal compression, and abnormal blood flow patteren.","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital anomaly of the great arteries","termid":"MONDO:0020292"},{"relation_name":"is_a","term_name":"branchial arch disease","termid":"MONDO:0022606"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aortic arch defects","secondary_identifiers":["UMLS:C5680872","Orphanet:1132","GARD:741","MEDGEN:1842770"],"termid":"MONDO:0015236","xrefs":{"Monarch":{"xref_id":"0015236"}}}


id: PBO:0003639
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"P-TEFb-associated cyclin-dependent protein kinase Cdk9","termid":"PBO:0003639"}


id: MONDO:0003213
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete ampulla of vater carcinoma (obsolete MONDO:0003213)","termid":"MONDO:0003213","xrefs":{"Monarch":{"xref_id":"0003213"}}}


id: GO:0086083
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.","definition_xrefs":["GOC:BHF","GOC:mtg_cardiac_conduct_nov11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding involved in heterotypic cell-cell adhesion","termid":"GO:0086080"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0098631"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515","GO:0098631"],"is_obsolete":false,"name":"cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication","termid":"GO:0086083"}


id: PATO:0001768
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A viability quality inhering in a bearer or a population by virtue of some of it's members' inability to survive to reproduce.","definition_xrefs":["PATOC:CVC"],"direct_ancestors":[{"relation_name":"is_a","term_name":"viability","termid":"PATO:0000169"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"semi-lethal (sensu genetics)","termid":"PATO:0001768"}


id: GO:0018205
data:
  {"annotated_genes":["SJAG_05032","SJAG_00727","SJAG_02082","SJAG_01164","SJAG_01776","SJAG_02503","SJAG_03843","SJAG_00604"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[105591],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009249"},{"annotations":[75949,115033,75795,72745,72855,76181,98089],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0016925"}]},"cv_name":"biological_process","definition":"The modification of peptidyl-lysine.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptidyl-amino acid modification","termid":"GO:0018193"}],"gene_count":8,"genes_by_uniquename":{"SJAG_00604":null,"SJAG_00727":null,"SJAG_01164":null,"SJAG_01776":null,"SJAG_02082":null,"SJAG_02503":null,"SJAG_03843":null,"SJAG_05032":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"peptidyl-lysine modification","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0018205","terms_by_termid":{"GO:0009249":null,"GO:0016925":null}}


id: PBO:0064487
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA polymerase theta","termid":"PBO:0064487"}


id: PBO:0086532
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; conserved among S. cerevisiae strains; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2","termid":"PBO:0086532"}


id: PBO:0113302
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in C/D snoRNP assembly; critical for formation of small nucleolar ribonucleoprotein complexes that are required for rRNA processing and 2'-O-methylation; regulates abundance of Rsa1p; required for growth at high temperature; mutations in human homolog ZNHIT3 cause PEHO syndrome, a ribosomopathy characterized by extreme cerebellar atrophy","termid":"PBO:0113302"}


id: PBO:0085859
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene; protein abundance increases in response to DNA replication stress; YLR108C has a paralog, YDR132C, that arose from the whole genome duplication","termid":"PBO:0085859"}


id: PBO:0030224
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_spindle_pole_body_morphology_during_vegetative_growth","termid":"PBO:0030224"}


id: PBO:0085777
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein needed for ER membrane biosynthesis in response to ER stress; member of the highly conserved FIT family of proteins involved in triglyceride droplet biosynthesis; homologous to human FIT2/FITM2, a fatty acyl-CoA diphosphatase; interacts with Sst2p and Hsp82p in high-throughput two-hybrid screens","termid":"PBO:0085777"}


id: GO:0051234
data:
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id: GO:1905488
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id: PBO:0003243
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id: PBO:0044020
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id: FYPO:0001908
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id: PBO:0057528
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id: PBO:0068045
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id: MONDO:0001380
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id: PBO:0030210
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id: MONDO:0005021
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id: GO:0097503
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id: GO:0052238
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id: PR:O94264
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id: PBO:0051380
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin kappa variable 6D-21 (non-functional)","termid":"PBO:0051380"}


id: PBO:0083613
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dynamin-like GTPase that mediates homotypic ER fusion; has a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; functional ortholog of the human atlastin ATL1, defects in which cause a form of the human disease hereditary spastic paraplegia; homolog of Arabidopsis RHD3","termid":"PBO:0083613"}


id: PBO:0049201
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GRIK1 antisense RNA 2","termid":"PBO:0049201"}


id: PBO:0039629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annexin A11","termid":"PBO:0039629"}


id: MONDO:0020066
data:
  {"annotated_genes":["SJAG_00183","SJAG_01005","SJAG_00222"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86780],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013800"},{"annotations":[87395],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012873"},{"annotations":[86363],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014139"}]},"cv_name":"mondo","definition":"The Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.","definition_xrefs":["PMID:28306229"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete dermis elastic tissue disorder (obsolete MONDO:0019292)","termid":"MONDO:0019292"},{"relation_name":"excluded_subClassOf","term_name":"hereditary disorder of connective tissue","termid":"MONDO:0023603"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"developmental defect during embryogenesis","termid":"MONDO:0019755"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00183":null,"SJAG_00222":null,"SJAG_01005":null},"genotype_count":0,"is_obsolete":false,"name":"Ehlers-Danlos syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NANDO:1200645","NORD:1080","MESH:D004535","OMIMPS:130000","ICD10CM:Q79.6","DOID:13359","MEDGEN:41720","icd11.foundation:1122707206","MedDRA:10014316","NCIT:C34568","GARD:6322","Orphanet:98249","SCTID:398114001","UMLS:C0013720","NANDO:2200607","ICD9:756.83"],"synonyms":[{"name":"Danlos Disease, Ehlers","type":"exact"},{"name":"Danlos disease","type":"exact"},{"name":"Disease, Ehlers Danlos","type":"exact"},{"name":"Disease, Ehlers-Danlos","type":"exact"},{"name":"Dystrophia mesodermalis congenita","type":"exact"},{"name":"ED syndrome","type":"related"},{"name":"EDS","type":"exact"},{"name":"Ehler Danlos Syndrome","type":"exact"},{"name":"Ehlers Danlos Disease","type":"exact"},{"name":"Ehlers Danlos Syndrome","type":"exact"},{"name":"Ehlers Danlos syndrome","type":"exact"},{"name":"Ehlers-Danlos Disease","type":"exact"},{"name":"Ehlers-Danlos syndromes","type":"exact"},{"name":"Fibrodysplasia elastica generalisata","type":"exact"},{"name":"Hereditary collagen dysplasia","type":"exact"},{"name":"Meekeren-Ehlers-Danlos syndrome","type":"exact"},{"name":"Syndrome, Ehlers-Danlos","type":"exact"},{"name":"danlos ehlers syndrome","type":"exact"},{"name":"elastic skin","type":"exact"},{"name":"skin elastic","type":"exact"}],"termid":"MONDO:0020066","terms_by_termid":{"MONDO:0012873":null,"MONDO:0013800":null,"MONDO:0014139":null},"xrefs":{"Monarch":{"xref_id":"0020066"}}}


id: PBO:0090530
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F1-FO ATP synthase subunit E","termid":"PBO:0090530"}


id: GO:0002503
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The binding of a peptide to the antigen binding groove of an MHC class II protein complex.","definition_xrefs":["GOC:add","PMID:15771591","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peptide antigen assembly with MHC protein complex","termid":"GO:0002501"},{"relation_name":"part_of","term_name":"MHC class II protein complex assembly","termid":"GO:0002399"},{"relation_name":"part_of","term_name":"antigen processing and presentation of peptide antigen via MHC class II","termid":"GO:0002495"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0008150","GO:0065003"],"is_obsolete":false,"name":"peptide antigen assembly with MHC class II protein complex","termid":"GO:0002503"}


id: GO:0051477
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a mannosylglycerate from one side of a membrane to the other.","definition_xrefs":["GOC:ai","PMID:15034926"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate transmembrane transporter activity","termid":"GO:0015144"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transporter activity","termid":"GO:0046943"},{"relation_name":"is_a","term_name":"carbohydrate derivative transmembrane transporter activity","termid":"GO:1901505"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"mannosylglycerate transmembrane transporter activity","termid":"GO:0051477"}


id: PBO:0072123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S15a","termid":"PBO:0072123"}


id: FYPO:0003982
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of disulfide oxidoreductase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal oxidoreductase activity","termid":"FYPO:0000689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0001985","FYPO:0000652","FYPO:0000707","FYPO:0000661"],"is_obsolete":false,"name":"abnormal disulfide oxidoreductase activity","termid":"FYPO:0003982"}


id: GO:0033869
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.","definition_xrefs":["GOC:mah","GOC:pde"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleoside bisphosphate metabolic process","termid":"GO:0033865"},{"relation_name":"is_a","term_name":"nucleoside phosphate catabolic process","termid":"GO:1901292"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"nucleoside bisphosphate catabolic process","synonyms":[{"name":"nucleoside bisphosphate breakdown","type":"exact"},{"name":"nucleoside bisphosphate catabolism","type":"exact"},{"name":"nucleoside bisphosphate degradation","type":"exact"}],"termid":"GO:0033869"}


id: GO:0097294
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.","definition_xrefs":["GOC:yaf","PMID:27590927"],"direct_ancestors":[{"relation_name":"is_a","term_name":"XMP biosynthetic process","termid":"GO:0097293"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0008150","GO:0055086","GO:0044281"],"is_obsolete":false,"name":"'de novo' XMP biosynthetic process","synonyms":[{"name":"'de novo' XMP anabolism","type":"exact"},{"name":"'de novo' XMP biosynthesis","type":"exact"},{"name":"'de novo' XMP formation","type":"exact"},{"name":"'de novo' XMP synthesis","type":"exact"}],"termid":"GO:0097294"}


id: PBO:0045491
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Down syndrome critical region 9","termid":"PBO:0045491"}


id: GO:0045476
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.","definition_xrefs":["PMID:11973306","CL:0000026","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"is_a","term_name":"programmed cell death involved in cell development","termid":"GO:0010623"},{"relation_name":"is_a","term_name":"apoptotic process involved in development","termid":"GO:1902742"},{"relation_name":"part_of","term_name":"oogenesis","termid":"GO:0048477"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"nurse cell apoptotic process","synonyms":[{"name":"apoptosis of nurse cells","type":"exact"},{"name":"invertebrate nurse cell apoptosis","type":"narrow"},{"name":"nurse cell apoptosis","type":"narrow"},{"name":"nurse cell programmed cell death by apoptosis","type":"exact"},{"name":"programmed cell death of nurse cells by apoptosis","type":"exact"}],"termid":"GO:0045476"}


id: GO:0009024
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.","definition_xrefs":["EC:2.7.1.144"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kinase activity","termid":"GO:0016301"},{"relation_name":"is_a","term_name":"phosphotransferase activity, alcohol group as acceptor","termid":"GO:0016773"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016301"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016301","GO:0016740","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"tagatose-6-phosphate kinase activity","secondary_identifiers":["RHEA:12420","MetaCyc:TAGAKIN-RXN"],"synonyms":[{"name":"ATP:D-tagatose-6-phosphate 1-phosphotransferase activity","type":"related"},{"name":"phosphotagatokinase activity","type":"related"}],"termid":"GO:0009024"}


id: GO:0034254
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amide catabolic process","termid":"GO:0034251"},{"relation_name":"is_a","term_name":"regulation of urea metabolic process","termid":"GO:0034255"},{"relation_name":"regulates","term_name":"urea catabolic process","termid":"GO:0043419"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0071941"}],"interesting_parent_ids":["GO:0008150","GO:0071941","GO:0044281"],"is_obsolete":false,"name":"regulation of urea catabolic process","synonyms":[{"name":"regulation of urea breakdown","type":"exact"},{"name":"regulation of urea catabolism","type":"exact"},{"name":"regulation of urea degradation","type":"exact"}],"termid":"GO:0034254"}


id: PBO:0060776
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NADH:ubiquinone oxidoreductase subunit B8 pseudogene 2","termid":"PBO:0060776"}


id: GO:0030445
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.","definition_xrefs":["GOC:mah","GOC:mcc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"fungal-type cell wall","termid":"GO:0009277"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0005618"}],"interesting_parent_ids":["GO:0005575","GO:0005618"],"is_obsolete":false,"name":"yeast-form cell wall","termid":"GO:0030445"}


id: PBO:0062453
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily E member 125 pseudogene","termid":"PBO:0062453"}


id: PATO:0025000
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A physical quality inhering in a bearer by virtue of the bearer's disposition to being fit to be used as a safe means of hydration.","definition_xrefs":["Wikipedia:https://en.wikipedia.org/wiki/Drinking_water"],"direct_ancestors":[{"relation_name":"is_a","term_name":"physical quality","termid":"PATO:0001018"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potability","synonyms":[{"name":"drinkability","type":"exact"}],"termid":"PATO:0025000"}


id: MONDO:0004032
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant mixed epithelial neoplasm that arises from the ovary and is composed predominantly of serous and endocervical-type mucinous epithelium.","definition_xrefs":["NCIT:C40090"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ovarian seromucinous tumor","termid":"MONDO:0003811"},{"relation_name":"is_a","term_name":"ovarian carcinoma","termid":"MONDO:0005140"},{"relation_name":"is_a","term_name":"malignant mixed neoplasm","termid":"MONDO:0005853"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"ovarian seromucinous carcinoma","secondary_identifiers":["DOID:6898","UMLS:C0279392","DOID:6899","ONCOTREE:OSMCA","ONCOTREE:MXOV","MEDGEN:1651770"],"synonyms":[{"name":"malignant ovarian mixed epithelial neoplasm","type":"exact"},{"name":"malignant ovarian mixed epithelial tumor","type":"exact"},{"name":"malignant ovarian mixed epithelial tumour","type":"exact"},{"name":"mixed epithelial carcinoma of ovary","type":"exact"},{"name":"mixed epithelial carcinoma of the ovary","type":"exact"},{"name":"mixed ovarian carcinoma","type":"related"},{"name":"ovarian Seromucinous carcinoma","type":"exact"},{"name":"ovarian mixed epithelial carcinoma","type":"exact"},{"name":"ovary mixed epithelial carcinoma","type":"exact"}],"termid":"MONDO:0004032","xrefs":{"Monarch":{"xref_id":"0004032"}}}


id: PBO:0030538
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cAMP_level_during_glucose_starvation","termid":"PBO:0030538"}


id: PBO:0076102
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"syntaxin 7","termid":"PBO:0076102"}


id: GO:0071911
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.","definition_xrefs":["GOC:dsf","PMID:19477156","PMID:20643933"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neurotransmitter secretion","termid":"GO:0007269"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"synchronous neurotransmitter secretion","termid":"GO:0071911"}


id: FYPO:0006436
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is abnormal when the cell is exposed to methyl methanesulfonate. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal S-phase DNA damage checkpoint","termid":"FYPO:0000007"},{"relation_name":"is_a","term_name":"abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate","termid":"FYPO:0005268"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000298","FYPO:0001985","FYPO:0005447","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate","synonyms":[{"name":"abnormal S-phase DNA damage checkpoint activation during cellular response to methyl methanesulfonate","type":"exact"},{"name":"abnormal S-phase DNA damage checkpoint during cellular response to MMS","type":"exact"},{"name":"abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate during mitotic cell cycle","type":"exact"},{"name":"abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate during vegetative growth","type":"exact"},{"name":"abnormal intra-S phase DNA damage checkpoint during cellular response to methyl methanesulfonate","type":"exact"},{"name":"abnormal mitotic S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate","type":"exact"}],"termid":"FYPO:0006436"}


id: PBO:0049532
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2A.Z histone pseudogene 3","termid":"PBO:0049532"}


id: PBO:0061831
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oxoglutarate dehydrogenase L","termid":"PBO:0061831"}


id: GO:0033602
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of dopamine secretion","termid":"GO:0014059"},{"relation_name":"is_a","term_name":"negative regulation of catecholamine secretion","termid":"GO:0033604"},{"relation_name":"negatively_regulates","term_name":"dopamine secretion","termid":"GO:0014046"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of dopamine secretion","synonyms":[{"name":"down regulation of dopamine secretion","type":"exact"},{"name":"down-regulation of dopamine secretion","type":"exact"},{"name":"downregulation of dopamine secretion","type":"exact"},{"name":"inhibition of dopamine secretion","type":"narrow"}],"termid":"GO:0033602"}


id: MONDO:0017684
data:
  {"annotated_genes":["SJAG_03434"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87006],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013166"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of amino acid and other organic acid metabolism","termid":"MONDO:0019189"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03434":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"disorder of beta and omega amino acid metabolism","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:308407","UMLS:C0342707","ICD9:270.8","GARD:21303","MEDGEN:575186","SCTID:237940008","icd11.foundation:446569334"],"termid":"MONDO:0017684","terms_by_termid":{"MONDO:0013166":null},"xrefs":{"Monarch":{"xref_id":"0017684"}}}


id: PBO:0066157
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RBBP8 N-terminal like","termid":"PBO:0066157"}


id: PBO:0084175
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Histidinolphosphatase; catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control","termid":"PBO:0084175"}


id: PBO:0056950
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 16-2","termid":"PBO:0056950"}


id: PBO:0029104
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_cellular_lysine_level","termid":"PBO:0029104"}


id: FYPO:0003504
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of protein measured in the plasma membrane is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased protein level during vegetative growth","termid":"FYPO:0001327"},{"relation_name":"is_a","term_name":"abnormal plasma membrane during vegetative growth","termid":"FYPO:0003278"},{"relation_name":"is_a","term_name":"altered level of substance in plasma membrane","termid":"FYPO:0008331"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0006551","FYPO:0000002"],"is_obsolete":false,"name":"increased protein level in plasma membrane","synonyms":[{"name":"increased plasma membrane protein level during vegetative growth","type":"exact"},{"name":"increased protein level in cell membrane during vegetative growth","type":"exact"},{"name":"increased protein level in plasma membrane during mitotic cell cycle","type":"related"},{"name":"increased protein level in plasma membrane during vegetative growth","type":"exact"},{"name":"protein accumulation in plasma membrane","type":"exact"}],"termid":"FYPO:0003504"}


id: PBO:0027797
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_growth_on_tetraplatin","termid":"PBO:0027797"}


id: PBO:0080593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat domain 20","termid":"PBO:0080593"}


id: PBO:0059056
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"modulator of apoptosis 1","termid":"PBO:0059056"}


id: PBO:0048505
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GDF5 antisense RNA 1","termid":"PBO:0048505"}


id: GO:0160114
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The structure which joins the B1 protofilament of the B tubule to the A10 and A11 protofilaments of the A tubule within an axonemal microtubule doublet.","definition_xrefs":["PMID:29430673","PMID:37295417","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"axonemal doublet microtubule","termid":"GO:0097545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"axonemal microtubule doublet outer junction","termid":"GO:0160114"}


id: PBO:0043992
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chondroitin sulfate N-acetylgalactosaminyltransferase 2","termid":"PBO:0043992"}


id: GO:0006302
data:
  {"annotated_genes":["SJAG_04142","SJAG_01076","SJAG_00327","SJAG_02527","SJAG_01573","SJAG_03436","SJAG_00441","SJAG_00475","SJAG_03720","SJAG_01873","SJAG_00153","SJAG_01652","SJAG_01938","SJAG_03994","SJAG_04971","SJAG_02339","SJAG_01624","SJAG_01698","SJAG_03026","SJAG_03855","SJAG_05372","SJAG_02460","SJAG_04372","SJAG_02237","SJAG_00935","SJAG_05373","SJAG_03160","SJAG_02465","SJAG_02294","SJAG_00796","SJAG_02837","SJAG_00757","SJAG_04210","SJAG_02616","SJAG_00369","SJAG_02556","SJAG_05232","SJAG_01832","SJAG_03048","SJAG_04199","SJAG_03221","SJAG_02267","SJAG_04530","SJAG_01776","SJAG_02262","SJAG_05105","SJAG_00857","SJAG_04039","SJAG_03417","SJAG_04995","SJAG_02708","SJAG_00696","SJAG_16460","SJAG_00623","SJAG_01878","SJAG_01205","SJAG_05295","SJAG_01044","SJAG_02822","SJAG_02545","SJAG_03702","SJAG_03722","SJAG_01611","SJAG_02079","SJAG_01332","SJAG_00177","SJAG_03454","SJAG_05237","SJAG_03942","SJAG_01677","SJAG_01354","SJAG_05180","SJAG_02828","SJAG_04457","SJAG_01708","SJAG_01762","SJAG_00823","SJAG_00805","SJAG_01067","SJAG_04183","SJAG_00980","SJAG_02690","SJAG_02698","SJAG_03926","SJAG_00640","SJAG_04843","SJAG_00884","SJAG_03898","SJAG_02575","SJAG_04932","SJAG_02104","SJAG_05323","SJAG_02348","SJAG_03941","SJAG_01410","SJAG_00213","SJAG_01173"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72071,72148,76293,79520,79673,92118,116131,117689,118099],"is_not":false,"summary":null,"term":"GO:0006302"},{"annotations":[112101,96341,80198,73320,72507,88861,89484],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000729"},{"annotations":[72633,65822,75465,76196,65243],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000730"},{"annotations":[89485,99388,108023,88863,117186],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990918"},{"annotations":[73819,99613,70333,71405,73633,77739,74975,78521,80651,80317,112412,72409,74778],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000727"},{"annotations":[116713,114275],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0097680"},{"annotations":[79750,95213,101509,106666,74661,88715,97013,71161,75621,106095,91194,100951,74621,70628,89486,104495,79869,108111,77482,78049,78460,103537,112104,79857,75315,97427,71703,104207,118256,72748,111866,79146,116640,117187,77490,80622,88364,78186,71000,118112],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000724"},{"annotations":[117188,111324,89487,105387,100278,112105,88865,114668],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006303"},{"annotations":[77327,76886,111194],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045002"},{"annotations":[75316],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000736"},{"annotations":[78310,71472,108513,117835],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045003"},{"annotations":[96209],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061674"},{"annotations":[79573,117190,108113],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000706"},{"annotations":[78894],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000707"},{"annotations":[108025,110674],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010772"},{"annotations":[100985],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:1902346"},{"annotations":[79748],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0097552"},{"annotations":[102705],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:2001033"},{"annotations":[110554,94213],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:2000781"},{"annotations":[107770],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:2001034"},{"annotations":[73035,91238],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:2000779"},{"annotations":[109687],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0010569"},{"annotations":[75601,72571,75237,70239],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990414"}]},"cv_name":"biological_process","definition":"The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.","definition_xrefs":["GOC:elh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA 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break repair","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-5693532"],"termid":"GO:0006302","terms_by_termid":{"GO:0000706":null,"GO:0000707":null,"GO:0000724":null,"GO:0000727":null,"GO:0000729":null,"GO:0000730":null,"GO:0000736":null,"GO:0006302":null,"GO:0006303":null,"GO:0010569":null,"GO:0010772":null,"GO:0045002":null,"GO:0045003":null,"GO:0061674":null,"GO:0097552":null,"GO:0097680":null,"GO:1902346":null,"GO:1990414":null,"GO:1990918":null,"GO:2000779":null,"GO:2000781":null,"GO:2001033":null,"GO:2001034":null}}


id: MONDO:0007533
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any hereditary elliptocytosis in which the cause of the disease is a mutation in the SPTA1 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial hemolytic anemia","termid":"MONDO:0003689"},{"relation_name":"is_a","term_name":"hereditary elliptocytosis","termid":"MONDO:0017319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"elliptocytosis 2","secondary_identifiers":["MESH:C565058","GARD:15064","OMIM:130600","UMLS:C1851741","MEDGEN:343643"],"synonyms":[{"name":"EL2","type":"related"},{"name":"SPTA1 hereditary elliptocytosis","type":"exact"},{"name":"elliptocytosis 2","type":"exact"},{"name":"elliptocytosis type 2","type":"exact"},{"name":"elliptocytosis, Rhesus-unlinked type","type":"related"},{"name":"elliptocytosis-2","type":"exact"},{"name":"hereditary elliptocytosis caused by mutation in SPTA1","type":"exact"}],"termid":"MONDO:0007533","xrefs":{"Monarch":{"xref_id":"0007533"}}}


id: GO:0060446
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of branches in the open tracheal system are generated and organized.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"branching morphogenesis of an epithelial tube","termid":"GO:0048754"},{"relation_name":"part_of","term_name":"open tracheal system development","termid":"GO:0007424"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"branching involved in open tracheal system development","termid":"GO:0060446"}


id: GO:0071573
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.","definition_xrefs":["GOC:vw","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-DNA complex assembly","termid":"GO:0065004"},{"relation_name":"part_of","term_name":"telomere organization","termid":"GO:0032200"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0032200"},{"rel_name":"is_a","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0065003","GO:0008150","GO:0032200","GO:0044085"],"is_obsolete":false,"name":"shelterin complex assembly","synonyms":[{"name":"Pot1 complex assembly","type":"related"},{"name":"Pot1-Tpz1 complex assembly","type":"related"},{"name":"shelterin complex formation","type":"related"},{"name":"telosome assembly","type":"exact"}],"termid":"GO:0071573"}


id: MONDO:0018315
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with decreased bone density (obsolete MONDO:0019704)","termid":"MONDO:0019704"},{"relation_name":"is_a","term_name":"osteoporosis","termid":"MONDO:0005298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"X-linked osteoporosis with fractures","secondary_identifiers":["GARD:17614","Orphanet:391330","UMLS:C5190610","MEDGEN:1674557"],"termid":"MONDO:0018315","xrefs":{"Monarch":{"xref_id":"0018315"}}}


id: PBO:0002451
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-type ATPase V0 subunit c'' (predicted)","termid":"PBO:0002451"}


id: FYPO:0006594
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which localization of the gamma-tubulin complex to the spindle pole body is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization during vegetative growth","termid":"FYPO:0000644"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001312","FYPO:0000257","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"normal gamma-tubulin complex localization to mitotic spindle pole body","synonyms":[{"name":"normal gamma-tubulin complex localisation to mitotic spindle pole body","type":"exact"},{"name":"normal gamma-tubulin complex localization to mitotic SPB","type":"exact"},{"name":"normal gamma-tubulin complex localization to mitotic spindle pole body during vegetative growth","type":"exact"},{"name":"normal gamma-tubulin complex localization to spindle pole body during mitotic cell cycle","type":"related"}],"termid":"FYPO:0006594"}


id: PBO:0119737
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"palmitoyl hydrolase inactive","termid":"PBO:0119737"}


id: GO:0051565
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of endoplasmic reticulum calcium ion concentration","termid":"GO:0032471"},{"relation_name":"is_a","term_name":"smooth endoplasmic reticulum calcium ion homeostasis","termid":"GO:0051563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098771"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0098771"],"is_obsolete":false,"name":"negative regulation of smooth endoplasmic reticulum calcium ion concentration","synonyms":[{"name":"reduction of calcium ion concentration in smooth ER","type":"exact"},{"name":"reduction of calcium ion concentration in smooth endoplasmic reticulum","type":"exact"},{"name":"reduction of smooth ER calcium ion concentration","type":"exact"},{"name":"reduction of smooth endoplasmic reticulum calcium ion concentration","type":"exact"},{"name":"smooth ER calcium ion concentration reduction","type":"exact"},{"name":"smooth endoplasmic reticulum calcium ion concentration reduction","type":"exact"}],"termid":"GO:0051565"}


id: MONDO:0004183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any nerve disorder affecting the axon of a nerve.","definition_xrefs":["NCIT:C27301"],"direct_ancestors":[{"relation_name":"is_a","term_name":"peripheral neuropathy","termid":"MONDO:0005244"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"axonal neuropathy","secondary_identifiers":["MEDGEN:266071","DOID:7319","SCTID:60703000","UMLS:C1263857"],"synonyms":[{"name":"axon peripheral neuropathy","type":"exact"},{"name":"axonal neuropathy","type":"exact"},{"name":"peripheral neuropathy of axon","type":"exact"}],"termid":"MONDO:0004183","xrefs":{"Monarch":{"xref_id":"0004183"}}}


id: PR:P24865
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- cig1 gene.","definition_xrefs":["UniProtKB:P24865","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G2/mitotic-specific cyclin cig1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC4E9.02","synonyms":[{"name":"Spom972h-cig1","type":"exact"}],"termid":"PR:P24865"}


id: GO:0071953
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.","definition_xrefs":["GOC:BHF","GOC:mah","PMID:20236620"],"direct_ancestors":[{"relation_name":"is_a","term_name":"supramolecular fiber","termid":"GO:0099512"},{"relation_name":"part_of","term_name":"extracellular matrix","termid":"GO:0031012"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"elastic fiber","synonyms":[{"name":"elastic fibre","type":"exact"},{"name":"elastin fiber","type":"exact"}],"termid":"GO:0071953"}


id: FYPO:0004637
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate and other catalytic properties of a DNA-directed DNA polymerase activity are normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal catalytic activity","termid":"FYPO:0000660"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"}],"interesting_parent_ids":["FYPO:0000654","FYPO:0000257","FYPO:0000652"],"is_obsolete":false,"name":"normal DNA-directed DNA polymerase activity","synonyms":[{"name":"normal DNA polymerase activity","type":"broad"}],"termid":"FYPO:0004637"}


id: MONDO:0044228
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Since the initial discovery of the human electroencephalogram (EEG) by {1:Berger (1929)}, it has been speculated that neural oscillations play a broad role in nervous systems and form the basis for higher cognitive functions and consciousness. The presence of a beta/gamma oscillation (18 to 50 Hz) is thought to represent an activated state of the underlying neuronal network. These beta (12-29 Hz) and gamma (30-50 Hz) brain rhythms involve gamma-aminobutyric acid type A (GABA-A) receptor action ({2:Haenschel et al., 2000}; summary by {3:Porjesz et al., 2002}).","definition_xrefs":["OMIM:130190"],"gene_count":0,"genotype_count":0,"name":"obsolete eegbqtl (obsolete MONDO:0044228)","synonyms":[{"name":"EEGBQTL","type":"related"},{"name":"ELECTROENCEPHALOGRAPHIC pattern, BETA frequency, quantitative trait locus","type":"related"}],"termid":"MONDO:0044228","xrefs":{"Monarch":{"xref_id":"0044228"}}}


id: PBO:0041127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"BTB domain containing 8","termid":"PBO:0041127"}


id: GO:0005016
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:jid"],"gene_count":0,"genotype_count":0,"name":"obsolete neurotrophin TRKC receptor activity (obsolete GO:0005016)","synonyms":[{"name":"neurotrophin TRKC receptor activity","type":"exact"}],"termid":"GO:0005016"}


id: MONDO:0009611
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"3-methylglutaconic aciduria (3-MGA) type IV, or unclassified 3-MGA, is a clinically heterogeneous disorder characterized by increased 3-methylglutaconic acid excretion in individuals that cannot be classified as having one of the other forms of 3-MGA (3-MGA I, II or III).","definition_xrefs":["Orphanet:67048"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3-methylglutaconic aciduria","termid":"MONDO:0017359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004736"],"is_obsolete":false,"name":"3-methylglutaconic aciduria type 4","secondary_identifiers":["DOID:0110006","OMIM:250951","UMLS:C1855126","GARD:10342","MESH:C565393","MEDGEN:344425","SCTID:297233004","icd11.foundation:185382411"],"synonyms":[{"name":"3 alpha methylglutaconic aciduria type IV","type":"related"},{"name":"3 methylglutaconic aciduria type IV","type":"related"},{"name":"3-METHYLGLUTACONIC aciduria, type IV","type":"related"},{"name":"3-Methylglutaconic aciduria, type 4","type":"related"},{"name":"3-methylglutaconic aciduria type IV","type":"exact"},{"name":"MGA type IV","type":"exact"},{"name":"MGA4","type":"exact"},{"name":"MGCA4","type":"exact"},{"name":"Mga, type 4","type":"related"},{"name":"Not otherwise specified 3-MGA-Uria type","type":"related"}],"termid":"MONDO:0009611","xrefs":{"Monarch":{"xref_id":"0009611"}}}


id: PBO:0065337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protogenin","termid":"PBO:0065337"}


id: PBO:0017712
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by A. thaliana GRF2","termid":"PBO:0017712"}


id: GO:2001076
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"regulation of metanephric ureteric bud development","termid":"GO:2001074"},{"relation_name":"positively_regulates","term_name":"metanephric part of ureteric bud development","termid":"GO:0035502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of metanephric ureteric bud development","termid":"GO:2001076"}


id: GO:0102355
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H+.","definition_xrefs":["EC:3.1.1.91","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003674","GO:0016788","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity","secondary_identifiers":["RHEA:33967","MetaCyc:RXN-13371"],"termid":"GO:0102355"}


id: GO:1905476
data:
  {"annotated_genes":["SJAG_03970","SJAG_04597","SJAG_02392"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[88409],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0042997"},{"annotations":[94741],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140325"},{"annotations":[96186],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903077"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.","definition_xrefs":["GOC:PARL","GO_REF:0000058","PMID:26911690","GOC:TermGenie","GOC:bc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein localization","termid":"GO:1903828"},{"relation_name":"is_a","term_name":"regulation of protein localization to membrane","termid":"GO:1905475"},{"relation_name":"negatively_regulates","term_name":"protein localization to membrane","termid":"GO:0072657"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02392":null,"SJAG_03970":null,"SJAG_04597":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of protein localization to membrane","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"down regulation of protein localisation in membrane","type":"exact"},{"name":"down regulation of protein localization in membrane","type":"exact"},{"name":"down regulation of protein localization to membrane","type":"exact"},{"name":"down-regulation of protein localisation in membrane","type":"exact"},{"name":"down-regulation of protein localization in membrane","type":"exact"},{"name":"down-regulation of protein localization to membrane","type":"exact"},{"name":"downregulation of protein localisation in membrane","type":"exact"},{"name":"downregulation of protein localization in membrane","type":"exact"},{"name":"downregulation of protein localization to membrane","type":"exact"},{"name":"inhibition of protein localisation in membrane","type":"narrow"},{"name":"inhibition of protein localization in membrane","type":"narrow"},{"name":"inhibition of protein localization to membrane","type":"narrow"},{"name":"negative regulation of protein localisation in membrane","type":"exact"},{"name":"negative regulation of protein localization in membrane","type":"exact"}],"termid":"GO:1905476","terms_by_termid":{"GO:0042997":null,"GO:0140325":null,"GO:1903077":null}}


id: MOD:01180
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts a glycine residue to 2-hydroxyglycine.","definition_xrefs":["PubMed:17431180","RESID:AA0434","ChEBI:38048","PubMed:16178056","PubMed:17823333"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monohydroxylated residue","termid":"MOD:00425"},{"relation_name":"is_a","term_name":"modified glycine residue","termid":"MOD:00908"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2-hydroxyglycine observational artifact","synonyms":[{"name":"2-hydroxyglycine","type":"exact"},{"name":"2HyGly","type":"exact"},{"name":"alpha-hydroxyglycine","type":"exact"},{"name":"amino(hydroxy)acetic acid","type":"exact"},{"name":"aminohydroxyacetic acid","type":"exact"}],"termid":"MOD:01180"}


id: PBO:0013792
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"IRC1-L/borderline left","termid":"PBO:0013792"}


id: PBO:0063926
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoinositide-3-kinase regulatory subunit 5","termid":"PBO:0063926"}


id: PBO:0068487
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U1 small nuclear 70, pseudogene","termid":"PBO:0068487"}


id: PBO:0034813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial protein associated with respiratory chain (predicted)","termid":"PBO:0034813"}


id: PBO:0039178
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"A-kinase anchoring protein 8 pseudogene 1","termid":"PBO:0039178"}


id: PBO:0067338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 431, pseudogene","termid":"PBO:0067338"}


id: MONDO:0001469
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"stomach disorder","termid":"MONDO:0004298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335"],"is_obsolete":false,"name":"cascade stomach","secondary_identifiers":["UMLS:C0267183","ICD9:537.6","MEDGEN:540460","DOID:12234","SCTID:54051005"],"synonyms":[{"name":"hourglass stricture or stenosis of stomach","type":"exact"}],"termid":"MONDO:0001469","xrefs":{"Monarch":{"xref_id":"0001469"}}}


id: MONDO:0014691
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Noonan syndrome in which the cause of the disease is a mutation in the SOS2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Noonan syndrome","termid":"MONDO:0018997"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267","MONDO:0005046"],"is_obsolete":false,"name":"Noonan syndrome 9","secondary_identifiers":["NCIT:C176937","OMIM:616559","DOID:0060587","UMLS:C4225282","GARD:16137","MEDGEN:896352"],"synonyms":[{"name":"NS9","type":"exact"},{"name":"Noonan syndrome 9","type":"exact"},{"name":"Noonan syndrome caused by mutation in SOS2","type":"exact"},{"name":"Noonan syndrome type 9","type":"exact"},{"name":"SOS2 Noonan syndrome","type":"exact"}],"termid":"MONDO:0014691","xrefs":{"Monarch":{"xref_id":"0014691"}}}


id: GO:0001935
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell proliferation","termid":"GO:0050673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endothelial cell proliferation","termid":"GO:0001935"}


id: GO:0039623
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.","definition_xrefs":["VZ:810"],"direct_ancestors":[{"relation_name":"is_a","term_name":"icosahedral viral capsid","termid":"GO:0019030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"T=25 icosahedral viral capsid","termid":"GO:0039623"}


id: PBO:0089817
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial inner membrane peptidase complex catalytic subunit 2","termid":"PBO:0089817"}


id: PBO:0003361
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.5.1.1","termid":"PBO:0003361"}


id: PBO:0069343
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 603, pseudogene","termid":"PBO:0069343"}


id: FYPO:0003754
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one mitotic spindle.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic spindle","termid":"FYPO:0000338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0002399"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000120"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0002399","FYPO:0000002","FYPO:0000054","FYPO:0000120","FYPO:0005447","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"multiple mitotic spindles","synonyms":[{"name":"additional mitotic spindles present during vegetative growth","type":"exact"},{"name":"extra mitotic spindles during vegetative growth","type":"exact"},{"name":"increased number of mitotic spindles","type":"exact"},{"name":"mitotic spindles present in greater numbers during vegetative growth","type":"exact"},{"name":"multiple spindles during mitosis","type":"exact"},{"name":"multiple spindles during mitotic cell cycle","type":"related"}],"termid":"FYPO:0003754"}


id: MONDO:0021317
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A cancer that involves the cerebellum.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"brain cancer","termid":"MONDO:0001657"},{"relation_name":"is_a","term_name":"cerebellar neoplasm","termid":"MONDO:0002913"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"cancer of cerebellum","secondary_identifiers":["MEDGEN:57797","UMLS:C0153640","NCIT:C3569","ICD9:191.6","SCTID:449420002"],"synonyms":[{"name":"cancer of cerebellum","type":"exact"},{"name":"cancer of the cerebellum","type":"exact"},{"name":"cerebellar cancer","type":"exact"},{"name":"cerebellar neoplasm, malignant","type":"exact"},{"name":"cerebellar tumor, malignant","type":"exact"},{"name":"cerebellum cancer","type":"exact"},{"name":"malignant cerebellar neoplasm","type":"exact"},{"name":"malignant cerebellar neoplasms","type":"exact"},{"name":"malignant cerebellar tumor","type":"exact"},{"name":"malignant cerebellar tumour","type":"exact"},{"name":"malignant cerebellum neoplasm","type":"exact"},{"name":"malignant neoplasm of cerebellum","type":"exact"},{"name":"malignant neoplasm of the cerebellum","type":"exact"},{"name":"malignant tumor of cerebellum","type":"exact"},{"name":"malignant tumor of the cerebellum","type":"exact"},{"name":"malignant tumour of cerebellum","type":"exact"},{"name":"malignant tumour of the cerebellum","type":"exact"}],"termid":"MONDO:0021317","xrefs":{"Monarch":{"xref_id":"0021317"}}}


id: PR:P05501
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A cytochrome b that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO05077","PANTHER:PTHR19271:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome b (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPMIT.05","secondary_identifiers":["UniProtKB:P05501"],"synonyms":[{"name":"Spom972h-MT-CYB","type":"exact"},{"name":"complex III subunit 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"complex III subunit III (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"cytochrome b-c1 complex subunit 3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"ubiquinol-cytochrome-c reductase complex cytochrome b subunit (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P05501"}


id: GO:0055042
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate.","definition_xrefs":["GOC:jid","GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lactonohydrolase activity","termid":"GO:0046573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016788","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"5-valerolactone hydrolase activity","termid":"GO:0055042"}


id: FYECO:0000405
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which isoleucine was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping excess","termid":"FYECO:0000109"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ ile","synonyms":[{"name":"isoleucine added","type":"exact"}],"termid":"FYECO:0000405"}


id: PBO:0089134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"client-loading PAQosome cofactor","termid":"PBO:0089134"}


id: PR:Q09740
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A glutamine--fructose-6-phosphate aminotransferase [isomerizing] that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glutamine--fructose-6-phosphate aminotransferase [isomerizing] (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC12C2.11","secondary_identifiers":["UniProtKB:Q09740"],"synonyms":[{"name":"D-fructose-6-phosphate amidotransferase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"GFAT (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-glmS","type":"exact"},{"name":"hexosephosphate aminotransferase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q09740"}


id: PBO:0059677
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO1 pseudogene 43","termid":"PBO:0059677"}


id: PBO:0030256
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_histone_H3-K9_acetylation","termid":"PBO:0030256"}


id: PBO:0072352
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S26 pseudogene 38","termid":"PBO:0072352"}


id: GO:0072251
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"juxtaglomerulus cell differentiation","termid":"GO:0072052"},{"relation_name":"is_a","term_name":"cell differentiation involved in metanephros development","termid":"GO:0072202"},{"relation_name":"part_of","term_name":"metanephric juxtaglomerular apparatus development","termid":"GO:0072206"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"metanephric juxtaglomerulus cell differentiation","termid":"GO:0072251"}


id: GO:1903667
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of chemorepellent activity.","definition_xrefs":["PMID:22711818","GOC:TermGenie","PMID:24390142","GO_REF:0000059"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of chemorepellent activity (obsolete GO:1903667)","synonyms":[{"name":"regulation of chemorepellant activity","type":"exact"}],"termid":"GO:1903667"}


id: GO:0002269
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.","definition_xrefs":["ISBN:0781735149","GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukocyte activation","termid":"GO:0045321"},{"relation_name":"part_of","term_name":"inflammatory response","termid":"GO:0006954"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"leukocyte activation involved in inflammatory response","synonyms":[{"name":"immune cell activation during inflammatory response","type":"related"},{"name":"leukocyte activation during inflammatory response","type":"related"}],"termid":"GO:0002269"}


id: PBO:0003156
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sulfiredoxin","termid":"PBO:0003156"}


id: MONDO:0006967
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete septic abortion (obsolete MONDO:0006967)","secondary_identifiers":["MedDRA:10040056","MESH:D000031"],"termid":"MONDO:0006967","xrefs":{"Monarch":{"xref_id":"0006967"}}}


id: PBO:0050711
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heat shock protein family B (small) member 9","termid":"PBO:0050711"}


id: GO:0022821
data:
  {"annotated_genes":["SJAG_04616"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[80393],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015386"}]},"cv_name":"molecular_function","definition":"Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.","definition_xrefs":["GOC:mtg_transport","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"potassium ion transmembrane transporter activity","termid":"GO:0015079"},{"relation_name":"is_a","term_name":"metal cation:monoatomic cation antiporter activity","termid":"GO:0140828"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04616":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"solute:potassium antiporter activity","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"potassium ion antiporter activity","type":"exact"}],"termid":"GO:0022821","terms_by_termid":{"GO:0015386":null}}


id: PBO:0045106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diencephalon/mesencephalon homeobox 1","termid":"PBO:0045106"}


id: MONDO:0012480
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any transient neonatal diabetes mellitus in which the cause of the disease is a mutation in the ABCC8 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transient neonatal diabetes mellitus","termid":"MONDO:0020525"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005015"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0005066","MONDO:0005015"],"is_obsolete":false,"name":"diabetes mellitus, transient neonatal, 2","secondary_identifiers":["UMLS:C1835887","SCTID:609580007","GARD:15482","MEDGEN:372150","MESH:C563672","OMIM:610374"],"synonyms":[{"name":"ABCC8 transient neonatal diabetes mellitus (disease)","type":"exact"},{"name":"Tndm2","type":"related"},{"name":"diabetes mellitus, transient neonatal 2","type":"exact"},{"name":"diabetes mellitus, transient neonatal, 2","type":"exact"},{"name":"diabetes mellitus, transient neonatal, type 2","type":"exact"},{"name":"transient neonatal diabetes mellitus (disease) caused by mutation in ABCC8","type":"exact"}],"termid":"MONDO:0012480","xrefs":{"Monarch":{"xref_id":"0012480"}}}


id: PBO:0083482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TDP1","termid":"PBO:0083482"}


id: GO:2000029
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of secondary metabolite biosynthetic process","termid":"GO:1900376"},{"relation_name":"is_a","term_name":"regulation of phenylpropanoid metabolic process","termid":"GO:2000762"},{"relation_name":"regulates","term_name":"proanthocyanidin biosynthetic process","termid":"GO:0010023"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"regulation of proanthocyanidin biosynthetic process","synonyms":[{"name":"regulation of proanthocyanidin anabolism","type":"exact"},{"name":"regulation of proanthocyanidin biosynthesis","type":"exact"},{"name":"regulation of proanthocyanidin formation","type":"exact"},{"name":"regulation of proanthocyanidin synthesis","type":"exact"}],"termid":"GO:2000029"}


id: PBO:0074633
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, H/ACA box 27","termid":"PBO:0074633"}


id: PBO:0064331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospholipid scramblase 1","termid":"PBO:0064331"}


id: PBO:0084450
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mannose-6-phosphate isomerase; catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation","termid":"PBO:0084450"}


id: GO:0060512
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of a prostate gland are generated and organized.","definition_xrefs":["GOC:dph","PMID:18977204"],"direct_ancestors":[{"relation_name":"is_a","term_name":"developmental process involved in reproduction","termid":"GO:0003006"},{"relation_name":"is_a","term_name":"gland morphogenesis","termid":"GO:0022612"},{"relation_name":"part_of","term_name":"prostate gland development","termid":"GO:0030850"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"prostate gland morphogenesis","termid":"GO:0060512"}


id: PBO:0003014
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"S. pombe specific GPI anchored protein family 1","termid":"PBO:0003014"}


id: PBO:0003155
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dual specificity protein kinase Mph1","termid":"PBO:0003155"}


id: PBO:0071696
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RPL38 pseudogene 2","termid":"PBO:0071696"}


id: PBO:0052535
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kallikrein related peptidase 8","termid":"PBO:0052535"}


id: PBO:0077440
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane protein 175","termid":"PBO:0077440"}


id: PBO:0001098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"multi-copy suppressor of Chk1","termid":"PBO:0001098"}


id: GO:0051978
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phospholipid transporter activity","termid":"GO:0005548"},{"relation_name":"is_a","term_name":"solute:sodium symporter activity","termid":"GO:0015370"},{"relation_name":"is_a","term_name":"organophosphate ester transmembrane transporter activity","termid":"GO:0015605"},{"relation_name":"is_a","term_name":"lipid transmembrane transporter activity","termid":"GO:0170055"},{"relation_name":"is_a","term_name":"carbohydrate derivative transmembrane transporter activity","termid":"GO:1901505"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"lysophospholipid:sodium symporter activity","synonyms":[{"name":"lysophospholipid transporter activity","type":"broad"}],"termid":"GO:0051978"}


id: PBO:0087880
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance; null exhibits disrupted mitochondrial metabolism and low cardiolipin content, strongly correlated with overproduction of inositol; binds to phosphatidic acid","termid":"PBO:0087880"}


id: PBO:0065846
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAB11A, member RAS oncogene family pseudogene 2","termid":"PBO:0065846"}


id: PBO:0056658
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit 25","termid":"PBO:0056658"}


id: MONDO:0005487
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A disorder in which the individual suffers from both symptoms that qualify as schizophrenia and symptoms that qualify as a mood disorder (e.g., depression or bipolar disorder) for a substantial portion (but not all) of the active period of the illness; for the remainder of the active period of the illness, the individual suffers from delusions or hallucinations in the absence of prominent mood symptoms.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"psychotic disorder","termid":"MONDO:0005485"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"}],"interesting_parent_ids":["MONDO:0002039"],"is_obsolete":false,"name":"schizoaffective disorder","secondary_identifiers":["NCIT:C94378","icd11.foundation:106339515","ICD9:295.7","EFO:0005411","UMLS:C0036337","DOID:5418","MEDGEN:11334"],"termid":"MONDO:0005487","xrefs":{"Monarch":{"xref_id":"0005487"}}}


id: GO:2000865
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion.","definition_xrefs":["GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of steroid hormone secretion","termid":"GO:2000832"},{"relation_name":"is_a","term_name":"regulation of estradiol secretion","termid":"GO:2000864"},{"relation_name":"negatively_regulates","term_name":"estradiol secretion","termid":"GO:0035938"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of estradiol secretion","synonyms":[{"name":"negative regulation of oestradiol secretion","type":"exact"}],"termid":"GO:2000865"}


id: SO:0000829
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A chromosome originating in a nucleomorph.","definition_xrefs":["SO:xp"],"direct_ancestors":[{"relation_name":"has_origin","term_name":"nucleomorphic_sequence","termid":"SO:0000739"},{"relation_name":"is_a","term_name":"chromosome","termid":"SO:0000340"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nucleomorphic_chromosome","synonyms":[{"name":"nucleomorphic chromosome","type":"exact"}],"termid":"SO:0000829"}


id: GO:0047127
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate.","definition_xrefs":["EC:1.5.1.25","MetaCyc:1.5.1.25-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"thiomorpholine-carboxylate dehydrogenase activity","secondary_identifiers":["Reactome:R-HSA-5693347"],"synonyms":[{"name":"ketimine reductase activity","type":"related"},{"name":"ketimine-reducing enzyme","type":"related"},{"name":"thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity","type":"related"}],"termid":"GO:0047127"}


id: MONDO:0000348
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete posterior polar cataract (obsolete MONDO:0000348)","secondary_identifiers":["DOID:0050537"],"synonyms":[{"name":"cataract, posterior polar","type":"exact"},{"name":"obsolete posterior polar cataract (disease)","type":"exact"}],"termid":"MONDO:0000348","xrefs":{"Monarch":{"xref_id":"0000348"}}}


id: PBO:0079709
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquilin 3","termid":"PBO:0079709"}


id: PBO:0073564
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Src homology 2 domain containing transforming protein D","termid":"PBO:0073564"}


id: PR:Q09886
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug42 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09886"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"meiotically up-regulated gene 42 protein (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC584.12","synonyms":[{"name":"Spom972h-mug42","type":"exact"}],"termid":"PR:Q09886"}


id: GO:0141151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of nitric oxide-cGMP mediated signal transduction.","definition_xrefs":["PMID:35931019"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of nitric oxide mediated signal transduction","termid":"GO:0010751"},{"relation_name":"is_a","term_name":"negative regulation of cGMP-mediated signaling","termid":"GO:0010754"},{"relation_name":"is_a","term_name":"regulation of nitric oxide-cGMP mediated signal transduction","termid":"GO:0141149"},{"relation_name":"negatively_regulates","term_name":"nitric oxide-cGMP-mediated signaling","termid":"GO:0038060"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of nitric oxide-cGMP mediated signal transduction","termid":"GO:0141151"}


id: MONDO:0020517
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A clinical variant of Langerhans cell histiocytosis characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults usually presenting with a lytic bone lesion. The etiology is unknown. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system disorder","termid":"MONDO:0005087"},{"relation_name":"is_a","term_name":"Langerhans cell histiocytosis","termid":"MONDO:0018310"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005570"],"is_obsolete":false,"name":"eosinophilic granuloma","secondary_identifiers":["UMLS:C0014461","MEDGEN:4979","MedDRA:10014956","Orphanet:99871","SCTID:129000002","icd11.foundation:1377407737","MESH:D004803","ICDO:9752/1","ICD9:277.89","NCIT:C3016"],"synonyms":[{"name":"Monostotic Langerhans cell histiocytosis","type":"exact"},{"name":"chronic and localised Langerhans cell histiocytosis","type":"exact"},{"name":"chronic and localized Langerhans cell histiocytosis","type":"exact"},{"name":"chronic unifocal Langerhans cell histiocytosis","type":"exact"},{"name":"eosinophilic granuloma","type":"exact"},{"name":"eosinophilic xanthomatous granuloma","type":"exact"},{"name":"unifocal Langerhans cell histiocytosis","type":"exact"}],"termid":"MONDO:0020517","xrefs":{"Monarch":{"xref_id":"0020517"}}}


id: GO:0061542
data:
  {"annotated_genes":["SJAG_04642"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[65370],"is_not":false,"summary":null,"term":"GO:0061542"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + S-adenosyl-L-homocysteine + H+.","definition_xrefs":["PMID:10777520","RHEA:44380","PMID:23190198"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-methyltransferase activity","termid":"GO:0008171"},{"relation_name":"is_a","term_name":"S-adenosylmethionine-dependent methyltransferase activity","termid":"GO:0008757"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04642":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016741"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016741","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"3-demethylubiquinol 3-O-methyltransferase activity","references_by_uniquename":{"GO_REF:0000003":null},"secondary_identifiers":["EC:2.1.1.64","Reactome:R-HSA-2162186"],"synonyms":[{"name":"2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase","type":"narrow"},{"name":"3-demethylubiquinol-n 3-O-methyltransferase activity","type":"exact"},{"name":"5-demethylubiquinone-10 methyltransferase","type":"narrow"},{"name":"5-demethylubiquinone-9 methyltransferase","type":"narrow"},{"name":"OMHMB-methyltransferase","type":"related"},{"name":"S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase","type":"related"}],"termid":"GO:0061542","terms_by_termid":{"GO:0061542":null}}


id: PBO:0040116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and SOCS box containing 3","termid":"PBO:0040116"}


id: MONDO:0041086
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"depressive disorder","termid":"MONDO:0002050"},{"relation_name":"is_a","term_name":"anxiety disorder","termid":"MONDO:0005618"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mixed anxiety and depressive disorder","secondary_identifiers":["SCTID:231504006","MEDGEN:572834","UMLS:C0338908"],"synonyms":[{"name":"anxiety depression","type":"related"},{"name":"mixed anxiety and depressive disorder","type":"exact"}],"termid":"MONDO:0041086","xrefs":{"Monarch":{"xref_id":"0041086"}}}


id: FYPO:0004218
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 20 of histone H4 does not occur.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished histone methylation during vegetative growth","termid":"FYPO:0002565"},{"relation_name":"is_a","term_name":"abnormal histone H4-K20 methylation during vegetative growth","termid":"FYPO:0004215"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0000002","FYPO:0002494"],"is_obsolete":false,"name":"abolished histone H4-K20 trimethylation during vegetative growth","synonyms":[{"name":"abolished histone H4 K20 trimethylation during vegetative growth","type":"exact"},{"name":"abolished histone H4-K20 trimethylation during mitotic cell cycle","type":"related"},{"name":"abolished histone H4K20me3 during vegetative growth","type":"exact"},{"name":"abolished histone lysine H4 K20 trimethylation during vegetative growth","type":"exact"},{"name":"histone H4-K20 trimethylation abolished during vegetative growth","type":"exact"},{"name":"histone H4-K20 trimethylation absent during vegetative growth","type":"exact"}],"termid":"FYPO:0004218"}


id: PBO:0084919
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Molecular chaperone of the endoplasmic reticulum lumen; involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway","termid":"PBO:0084919"}


id: PBO:0051077
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy diversity 6-19","termid":"PBO:0051077"}


id: GO:0030515
data:
  {"annotated_genes":["SJAG_00083","SJAG_04069","SJAG_02300","SJAG_01907","SJAG_02608","SJAG_04908","SJAG_05186","SJAG_02372","SJAG_02377","SJAG_03028","SJAG_00572","SJAG_04424","SJAG_01234","SJAG_02662","SJAG_03341","SJAG_00897","SJAG_03125","SJAG_00744","SJAG_00559","SJAG_00344","SJAG_02530","SJAG_00945","SJAG_03569","SJAG_04942","SJAG_00566","SJAG_02702","SJAG_04339","SJAG_03654","SJAG_05187","SJAG_02025","SJAG_01764","SJAG_03156","SJAG_00879","SJAG_04754","SJAG_03846","SJAG_03252","SJAG_04224"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[64227,71221,73848,75834,76332,76401,79559,80056,80508,89562,91644,92376,92969,93163,98850,101098,101914,106344,106579,108405,108972,110093,110469,110944,111435,112155,112378,114291],"is_not":false,"summary":null,"term":"GO:0030515"},{"annotations":[95691,101504,74858,90338],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034513"},{"annotations":[78300,74682,78427,66413,76076],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034511"}]},"cv_name":"molecular_function","definition":"Binding to a small nucleolar RNA.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA binding","termid":"GO:0003723"}],"gene_count":37,"genes_by_uniquename":{"SJAG_00083":null,"SJAG_00344":null,"SJAG_00559":null,"SJAG_00566":null,"SJAG_00572":null,"SJAG_00744":null,"SJAG_00879":null,"SJAG_00897":null,"SJAG_00945":null,"SJAG_01234":null,"SJAG_01764":null,"SJAG_01907":null,"SJAG_02025":null,"SJAG_02300":null,"SJAG_02372":null,"SJAG_02377":null,"SJAG_02530":null,"SJAG_02608":null,"SJAG_02662":null,"SJAG_02702":null,"SJAG_03028":null,"SJAG_03125":null,"SJAG_03156":null,"SJAG_03252":null,"SJAG_03341":null,"SJAG_03569":null,"SJAG_03654":null,"SJAG_03846":null,"SJAG_04069":null,"SJAG_04224":null,"SJAG_04339":null,"SJAG_04424":null,"SJAG_04754":null,"SJAG_04908":null,"SJAG_04942":null,"SJAG_05186":null,"SJAG_05187":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003723","GO:0003674","GO:0005488"],"is_obsolete":false,"name":"snoRNA binding","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0030515","terms_by_termid":{"GO:0030515":null,"GO:0034511":null,"GO:0034513":null}}


id: PBO:0046430
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EPH receptor B6","termid":"PBO:0046430"}


id: PBO:0067579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 736, pseudogene","termid":"PBO:0067579"}


id: GO:1904210
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex.","definition_xrefs":["PMID:17000876","GO_REF:0000079","GOC:PARL","GOC:TermGenie","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"VCP-NPL4-UFD1 AAA ATPase complex assembly","synonyms":[{"name":"Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly","type":"narrow"},{"name":"Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation","type":"narrow"},{"name":"VCP-NPL4-UFD1 AAA ATPase complex formation","type":"exact"},{"name":"p97-Ufd1-Npl4 complex assembly","type":"exact"},{"name":"p97-Ufd1-Npl4 complex formation","type":"exact"}],"termid":"GO:1904210"}


id: PBO:0058142
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4438","termid":"PBO:0058142"}


id: PBO:0079262
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tetratricopeptide repeat domain 33","termid":"PBO:0079262"}


id: SO:0001740
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene with a translational start codon of CUG.","definition_xrefs":["SO:mc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene_with_non_canonical_start_codon","termid":"SO:0001739"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gene_with_start_codon_CUG","synonyms":[{"name":"gene with start codon CUG","type":"exact"}],"termid":"SO:0001740"}


id: FYPO:0004156
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is lower than normal. Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein level during vegetative growth","termid":"FYPO:0001324"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"output_of","termid":"FYPO:0006551"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0006551","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein level during mitosis","synonyms":[{"name":"decreased protein accumulation during mitosis","type":"related"},{"name":"decreased protein level during mitosis during vegetative growth","type":"exact"},{"name":"decreased protein level during mitotic M phase","type":"related"},{"name":"decreased protein level during mitotic nuclear division","type":"exact"},{"name":"reduced protein level during mitosis","type":"exact"}],"termid":"FYPO:0004156"}


id: PBO:0067127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 173, pseudogene","termid":"PBO:0067127"}


id: MONDO:0014374
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any nephronophthisis in which the cause of the disease is a mutation in the CEP83 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nephronophthisis","termid":"MONDO:0019005"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005240"],"is_obsolete":false,"name":"nephronophthisis 18","secondary_identifiers":["DOID:0111125","UMLS:C3890591","MEDGEN:855697","OMIM:615862"],"synonyms":[{"name":"CEP83 nephronophthisis (disease)","type":"exact"},{"name":"NPHP18","type":"exact"},{"name":"nephronophthisis (disease) caused by mutation in CEP83","type":"exact"},{"name":"nephronophthisis 18","type":"exact"},{"name":"nephronophthisis type 18","type":"exact"}],"termid":"MONDO:0014374","xrefs":{"Monarch":{"xref_id":"0014374"}}}


id: MONDO:0008688
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"WT limb-blood syndrome is characterized by hematological anomalies (Fanconi anemia, leukemia and lymphoma) often appearing during childhood. Anomalies of the limbs and hands are also present: bifid or hypoplastic thumbs, cutaneous syndactyly, and ulnar and radial defects. The syndrome has been described in several families. Transmission is autosomal dominant.","definition_xrefs":["Orphanet:3466"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited aplastic anemia","termid":"MONDO:0001713"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0002280"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"WT limb-blood syndrome","secondary_identifiers":["UMLS:C1327917","icd11.foundation:1407849410","MEDGEN:231231","MESH:C536751","SCTID:719019000","GARD:39","OMIM:194350"],"synonyms":[{"name":"WT limb blood syndrome","type":"related"},{"name":"WT limb-blood syndrome","type":"exact"},{"name":"WTsyndrome","type":"related"},{"name":"radial-ulnar hypoplasia with bone marrow failure and/or leukaemia","type":"related"},{"name":"radial-ulnar hypoplasia with bone marrow failure and/or leukemia","type":"related"}],"termid":"MONDO:0008688","xrefs":{"Monarch":{"xref_id":"0008688"}}}


id: GO:0042797
data:
  {"annotated_genes":["SJAG_02101","SJAG_04934","SJAG_04261","SJAG_01765","SJAG_04408"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75526,76871,77396,80030,111852],"is_not":false,"summary":null,"term":"GO:0042797"}]},"cv_name":"biological_process","definition":"The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.","definition_xrefs":["ISBN:0321000382","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription by RNA polymerase III","termid":"GO:0006383"},{"relation_name":"is_a","term_name":"tRNA transcription","termid":"GO:0009304"}],"gene_count":5,"genes_by_uniquename":{"SJAG_01765":null,"SJAG_02101":null,"SJAG_04261":null,"SJAG_04408":null,"SJAG_04934":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006351"},{"rel_name":"is_a","termid":"GO:0006399"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0006399","GO:0006351","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"tRNA transcription by RNA polymerase III","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"tRNA transcription from Pol III promoter","type":"exact"},{"name":"tRNA transcription from RNA polymerase III promoter","type":"exact"}],"termid":"GO:0042797","terms_by_termid":{"GO:0042797":null}}


id: MONDO:0001713
data:
  {"annotated_genes":["SJAG_00749","SJAG_02046","SJAG_02556","SJAG_02597","SJAG_01568","SJAG_02280","SJAG_02708","SJAG_01410","SJAG_03335","SJAG_02335","SJAG_01296","SJAG_00465","SJAG_01621","SJAG_04695","SJAG_02749","SJAG_02585","SJAG_00468","SJAG_01512","SJAG_04414","SJAG_01366","SJAG_00921","SJAG_05180","SJAG_02358","SJAG_02339","SJAG_00166","SJAG_02904","SJAG_01588","SJAG_03254","SJAG_00611","SJAG_04746","SJAG_04478","SJAG_02802","SJAG_04168","SJAG_04204","SJAG_04066","SJAG_01840","SJAG_03919","SJAG_02340","SJAG_02894","SJAG_03762"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86639],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013851"},{"annotations":[85854,85853],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007110"},{"annotations":[86624,86625],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013217"},{"annotations":[87514],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013964"},{"annotations":[86149,86148],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014245"},{"annotations":[86724],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014394"},{"annotations":[85662],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010493"},{"annotations":[86754,86753],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011639"},{"annotations":[87149,87148],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044309"},{"annotations":[87152],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044310"},{"annotations":[86383,86382],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032668"},{"annotations":[86384],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032669"},{"annotations":[86386,86387],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032670"},{"annotations":[86104],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0031071"},{"annotations":[86182,86183],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012529"},{"annotations":[87086,87087],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012924"},{"annotations":[87084,87085],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012925"},{"annotations":[87102,87103],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012937"},{"annotations":[87101,87100],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012938"},{"annotations":[87104],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012939"},{"annotations":[86626,86627],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013216"},{"annotations":[86650],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013248"},{"annotations":[87074],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013499"},{"annotations":[85358],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014108"},{"annotations":[87329],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014986"},{"annotations":[87333],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014987"},{"annotations":[87330],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014985"}]},"cv_name":"mondo","definition":"An inborn condition characterized by deficiencies of red cell precursors that sometimes also includes leukopenia and thrombocytopenia.","definition_xrefs":["MESH:D029502"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"idiopathic aplastic anemia","termid":"MONDO:0012197"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"aplastic anemia","termid":"MONDO:0015909"}],"gene_count":40,"genes_by_uniquename":{"SJAG_00166":null,"SJAG_00465":null,"SJAG_00468":null,"SJAG_00611":null,"SJAG_00749":null,"SJAG_00921":null,"SJAG_01296":null,"SJAG_01366":null,"SJAG_01410":null,"SJAG_01512":null,"SJAG_01568":null,"SJAG_01588":null,"SJAG_01621":null,"SJAG_01840":null,"SJAG_02046":null,"SJAG_02280":null,"SJAG_02335":null,"SJAG_02339":null,"SJAG_02340":null,"SJAG_02358":null,"SJAG_02556":null,"SJAG_02585":null,"SJAG_02597":null,"SJAG_02708":null,"SJAG_02749":null,"SJAG_02802":null,"SJAG_02894":null,"SJAG_02904":null,"SJAG_03254":null,"SJAG_03335":null,"SJAG_03762":null,"SJAG_03919":null,"SJAG_04066":null,"SJAG_04168":null,"SJAG_04204":null,"SJAG_04414":null,"SJAG_04478":null,"SJAG_04695":null,"SJAG_04746":null,"SJAG_05180":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002280"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0002280"],"is_obsolete":false,"name":"inherited aplastic anemia","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:68383","DOID:1342","ICD9:284.0","GARD:18889","ICD9:284.09","ICD10CM:D61.0","NANDO:1200302","SCTID:28975000","UMLS:C5681331","NANDO:2201275","MEDGEN:1826154"],"synonyms":[{"name":"congenital aplastic anaemia","type":"related"},{"name":"congenital aplastic anemia","type":"related"},{"name":"congenital hypoplastic anaemia","type":"related"},{"name":"congenital hypoplastic anemia","type":"related"},{"name":"constitutional aplastic anaemia","type":"exact"},{"name":"constitutional aplastic anemia","type":"exact"},{"name":"hereditary aplastic anaemia","type":"exact"},{"name":"hereditary aplastic anemia","type":"exact"},{"name":"hypoplastic anaemia - familial","type":"related"},{"name":"hypoplastic anemia - familial","type":"related"},{"name":"rare constitutional aplastic anaemia","type":"narrow"},{"name":"rare constitutional aplastic anemia","type":"narrow"}],"termid":"MONDO:0001713","terms_by_termid":{"MONDO:0007110":null,"MONDO:0010493":null,"MONDO:0011639":null,"MONDO:0012529":null,"MONDO:0012924":null,"MONDO:0012925":null,"MONDO:0012937":null,"MONDO:0012938":null,"MONDO:0012939":null,"MONDO:0013216":null,"MONDO:0013217":null,"MONDO:0013248":null,"MONDO:0013499":null,"MONDO:0013851":null,"MONDO:0013964":null,"MONDO:0014108":null,"MONDO:0014245":null,"MONDO:0014394":null,"MONDO:0014985":null,"MONDO:0014986":null,"MONDO:0014987":null,"MONDO:0031071":null,"MONDO:0032668":null,"MONDO:0032669":null,"MONDO:0032670":null,"MONDO:0044309":null,"MONDO:0044310":null},"xrefs":{"Monarch":{"xref_id":"0001713"}}}


id: GO:0046791
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any viral process that results in the inhibition of complement neutralization of the host cell.","definition_xrefs":["PMID:10587354"],"gene_count":0,"genotype_count":0,"name":"obsolete suppression by virus of host complement neutralization (obsolete GO:0046791)","synonyms":[{"name":"negative regulation by virus of host complement neutralization","type":"exact"},{"name":"suppression by virus of host complement neutralization","type":"exact"}],"termid":"GO:0046791"}


id: PBO:0044291
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome X open reading frame 66","termid":"PBO:0044291"}


id: GO:0046476
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycosylceramide metabolic process","termid":"GO:0006677"},{"relation_name":"is_a","term_name":"glycosphingolipid biosynthetic process","termid":"GO:0006688"},{"relation_name":"is_a","term_name":"ceramide biosynthetic process","termid":"GO:0046513"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0006629"],"is_obsolete":false,"name":"glycosylceramide biosynthetic process","synonyms":[{"name":"glycosylceramide anabolism","type":"exact"},{"name":"glycosylceramide biosynthesis","type":"exact"},{"name":"glycosylceramide formation","type":"exact"},{"name":"glycosylceramide synthesis","type":"exact"}],"termid":"GO:0046476"}


id: PBO:0063627
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"profilin 1 pseudogene 3","termid":"PBO:0063627"}


id: GO:2000352
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.","definition_xrefs":["GOC:mtg_apoptosis","GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of apoptotic process","termid":"GO:0043066"},{"relation_name":"is_a","term_name":"regulation of endothelial cell apoptotic process","termid":"GO:2000351"},{"relation_name":"negatively_regulates","term_name":"endothelial cell apoptotic process","termid":"GO:0072577"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of endothelial cell apoptotic process","synonyms":[{"name":"negative regulation of apoptosis of endothelial cells","type":"exact"},{"name":"negative regulation of endothelial cell apoptosis","type":"narrow"},{"name":"negative regulation of endothelial cell programmed cell death by apoptosis","type":"exact"},{"name":"negative regulation of killing of endothelial cells","type":"exact"},{"name":"negative regulation of programmed cell death of endothelial cells by apoptosis","type":"exact"},{"name":"negative regulation of programmed cell death, endothelial cells","type":"exact"}],"termid":"GO:2000352"}


id: MONDO:0021761
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An erythrocytic disorder that is characterized by macrocytosis and megaloblastic changes of the bone marrow cells, with additional morphological defects of hands and feet.","definition_xrefs":["PMID:7641772"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acral dysostosis dyserythropoiesis syndrome","termid":"MONDO:0021761","xrefs":{"Monarch":{"xref_id":"0021761"}}}


id: GO:0008115
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + O2 + sarcosine = formaldehyde + glycine + H2O2.","definition_xrefs":["RHEA:13313","EC:1.5.3.1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor","termid":"GO:0016647"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"sarcosine oxidase activity","secondary_identifiers":["MetaCyc:SARCOX-RXN","KEGG_REACTION:R00610"],"synonyms":[{"name":"sarcosine:oxygen oxidoreductase (demethylating)","type":"related"}],"termid":"GO:0008115"}


id: FYPO:0004624
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which equatorial microtubule organizing center (eMTOC) assembly does not occur. eMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center.","definition_xrefs":["PomBase:mah","PMID:15004232","GO:1904185"],"direct_ancestors":[{"relation_name":"has_output","term_name":"eMTOC absent from cell","termid":"FYPO:0005687"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"},{"relation_name":"is_a","term_name":"abnormal eMTOC assembly","termid":"FYPO:0005690"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000054"],"is_obsolete":false,"name":"abolished eMTOC assembly","synonyms":[{"name":"abolished eMTOC assembly during mitotic cell cycle","type":"related"},{"name":"abolished eMTOC assembly during vegetative growth","type":"exact"},{"name":"abolished eMTOC formation","type":"exact"},{"name":"abolished equatorial microtubule organizing center assembly","type":"exact"},{"name":"abolished equatorial microtubule organizing center formation","type":"exact"},{"name":"eMTOC abolished","type":"exact"}],"termid":"FYPO:0004624"}


id: PBO:0074967
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 114-9","termid":"PBO:0074967"}


id: PBO:0078857
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TRPC6 pseudogene 5","termid":"PBO:0078857"}


id: GO:0043049
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.","definition_xrefs":["PMID:12668634","GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ectodermal placode formation","termid":"GO:0060788"},{"relation_name":"part_of","term_name":"otic vesicle formation","termid":"GO:0030916"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"otic placode formation","termid":"GO:0043049"}


id: PR:Q10093
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC11D3.14c gene.","definition_xrefs":["UniProtKB:Q10093","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C11D3.14c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC11D3.14c","synonyms":[{"name":"Spom972h-SPAC11D3.14c","type":"exact"}],"termid":"PR:Q10093"}


id: MONDO:0026186
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete genetic developmental defect of the eye (obsolete MONDO:0026186)","secondary_identifiers":["Orphanet:183557"],"termid":"MONDO:0026186","xrefs":{"Monarch":{"xref_id":"0026186"}}}


id: GO:1990715
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an mRNA molecule coding sequence (CDS).","definition_xrefs":["GOC:kmv","PMID:25805859","SO:0000316"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mRNA binding","termid":"GO:0003729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003723"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0003723"],"is_obsolete":false,"name":"mRNA CDS binding","synonyms":[{"name":"mRNA coding region binding","type":"exact"},{"name":"mRNA coding sequence binding","type":"exact"}],"termid":"GO:1990715"}


id: PBO:0083837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p","termid":"PBO:0083837"}


id: PBO:0082187
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alcohol dehydrogenase; fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway; ADH1 has a paralog, ADH5, that arose from the whole genome duplication","termid":"PBO:0082187"}


id: PBO:0076624
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tubulin folding cofactor E like","termid":"PBO:0076624"}


id: PBO:0046986
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 86 member K, pseudogene","termid":"PBO:0046986"}


id: MONDO:0006521
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cutaneous eruptions resembling acne, characterized by the presence of papulonodules, pustules, comedones, or cysts in the face, trunk, and extremities. Causes include infections and the use of certain medications (e.g., antibiotics and steroids).","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dermatitis","termid":"MONDO:0002406"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"acneiform dermatitis","secondary_identifiers":["NCIT:C35277","UMLS:C0234894","EFO:1000662","MEDGEN:68607","DOID:4399"],"synonyms":[{"name":"Rash acneiform","type":"exact"}],"termid":"MONDO:0006521","xrefs":{"Monarch":{"xref_id":"0006521"}}}


id: FYPO:0007397
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of heme into the cell is abolished.","definition_xrefs":["GO:0140420","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular process during vegetative growth","termid":"FYPO:0001362"},{"relation_name":"is_a","term_name":"abnormal transport","termid":"FYPO:0001720"},{"relation_name":"is_a","term_name":"abolished biological process","termid":"FYPO:0005448"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0005447","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"abolished heme import","synonyms":[{"name":"abolished haem import","type":"exact"},{"name":"abolished heme import during mitotic cell cycle","type":"related"},{"name":"abolished heme import during vegetative growth","type":"exact"},{"name":"abolished heme import into cell","type":"exact"},{"name":"heme import abolished during vegetative growth","type":"exact"}],"termid":"FYPO:0007397"}


id: PBO:0073980
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 24 member 1","termid":"PBO:0073980"}


id: PBO:0046962
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FAM83A antisense RNA 1","termid":"PBO:0046962"}


id: FYPO:0001584
data:
  {"alleles_by_uniquename":{"SJAG_01143:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_01143","name":"mid1delta","uniquename":"SJAG_01143:allele-1"},"SJAG_02392:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_02392","name":"pom1delta","uniquename":"SJAG_02392:allele-1"},"SJAG_04280:allele-1":{"allele_type":"amino_acid_mutation","description":"T582G","gene_uniquename":"SJAG_04280","name":"wee1-as8","uniquename":"SJAG_04280:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"multi_locus_phenotype":[{"annotations":[119759],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0005503"}],"single_locus_phenotype":[{"annotations":[119533,119753,119535,119532],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0005503"},{"annotations":[119534],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"FYPO:0002870"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization during vegetative growth","termid":"FYPO:0000443"},{"relation_name":"is_a","term_name":"abnormal protein localization to cell tip","termid":"FYPO:0005987"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00030":null,"SJAG_01143":null,"SJAG_01794":null,"SJAG_02392":null,"SJAG_03581":null,"SJAG_03596":null,"SJAG_04280":null,"SJAG_04522":null},"genotype_count":3,"genotypes_by_uniquename":{"mid1delta__pom1delta":{"display_name":"mid1delta pom1delta","display_uniquename":"mid1delta__pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_01143:allele-1","expression":"Null"}]},{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]},"pom1delta":{"display_name":"pom1delta","display_uniquename":"pom1delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_02392:allele-1","expression":"Null"}]}]},"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type":{"display_name":"wee1-as8(T582G aa)","display_uniquename":"wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04280:allele-1","expression":"Not assayed or wild type"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320","FYPO:0000138","FYPO:0005447"],"is_obsolete":false,"multi_locus_annotated_genes":["SJAG_02392","SJAG_01143"],"name":"abnormal protein localization to cell tip during vegetative growth","references_by_uniquename":{"PMID:25866389":null,"PMID:30664646":null},"single_locus_annotated_genes":["SJAG_04280","SJAG_02392"],"single_locus_genotype_uniquenames":["pom1delta","wee1-as8-T582G-amino_acid_mutation-expression-not_assayed_or_wild_type"],"synonyms":[{"name":"abnormal protein localisation to cell tip during vegetative growth","type":"exact"},{"name":"abnormal protein localization to cell end during vegetative growth","type":"exact"},{"name":"abnormal protein localization to cell tip during mitotic cell cycle","type":"related"}],"termid":"FYPO:0001584","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000137":null,"FYECO:0000338":null,"FYPO:0002870":null,"FYPO:0005503":null}}


id: GO:0099191
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"trans-synaptic signaling","termid":"GO:0099537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"trans-synaptic signaling by BDNF","synonyms":[{"name":"trans-synaptic signaling by brain-derived neurotrophic factor","type":"exact"}],"termid":"GO:0099191"}


id: GO:0071542
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.","definition_xrefs":["GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron differentiation","termid":"GO:0030182"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dopaminergic neuron differentiation","termid":"GO:0071542"}


id: PBO:0089098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coatomer gamma subunit Sec21","termid":"PBO:0089098"}


id: MONDO:0015649
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Micturition-induced seizures is a rare neurologic disease characterized by tonic posturing or clonic movements triggered by micturition, with bilateral or unilateral involvement of the extremities and with or without loss of consciousness. Developmental delay is reported in some cases.","definition_xrefs":["Orphanet:166430"],"direct_ancestors":[{"relation_name":"is_a","term_name":"reflex epilepsy","termid":"MONDO:0017768"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027"],"is_obsolete":false,"name":"micturation-induced seizures","secondary_identifiers":["UMLS:C4706587","MEDGEN:1646690","GARD:20082"],"termid":"MONDO:0015649","xrefs":{"Monarch":{"xref_id":"0015649"}}}


id: PBO:0005793
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ER membrane protein DP1/Yop1","termid":"PBO:0005793"}


id: PBO:0065593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"prothymosin alpha pseudogene 9","termid":"PBO:0065593"}


id: MONDO:0003145
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A central nervous system embryonal tumor, not otherwise specified arising from the supratentorial region.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"supratentorial cancer","termid":"MONDO:0002071"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"supratentorial primitive neuroectodermal tumor","secondary_identifiers":["NCIT:C6968","UMLS:C1336538","DOID:4791","ICD9:209.30","SCTID:699318007","MEDGEN:234914"],"synonyms":[{"name":"CNS/supratentorial PNET","type":"exact"},{"name":"supratent. primitive neuro. tumor","type":"exact"},{"name":"supratent. primitive neuro. tumour","type":"exact"},{"name":"supratentorial PNET","type":"exact"},{"name":"supratentorial primitive neuroectodermal tumor","type":"exact"}],"termid":"MONDO:0003145","xrefs":{"Monarch":{"xref_id":"0003145"}}}


id: PBO:0116601
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KANK1 antisense RNA 1","termid":"PBO:0116601"}


id: GO:1902329
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any DNA replication termination that is involved in bacterial-type DNA replication.","definition_xrefs":["GOC:TermGenie","GOC:mtg_cell_cycle"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell cycle DNA replication termination","termid":"GO:1902294"},{"relation_name":"part_of","term_name":"bacterial-type DNA replication","termid":"GO:0044787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"is_a","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006259"},{"rel_name":"part_of","termid":"GO:0006260"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006259","GO:0006260","GO:0008150","GO:0007049"],"is_obsolete":false,"name":"bacterial-type DNA replication termination","synonyms":[{"name":"DNA replication termination involved in bacterial-type DNA replication","type":"exact"}],"termid":"GO:1902329"}


id: GO:0042741
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"antibiotic catabolic process","termid":"GO:0017001"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endogenous antibiotic catabolic process","synonyms":[{"name":"endogenous antibiotic breakdown","type":"exact"},{"name":"endogenous antibiotic catabolism","type":"exact"},{"name":"endogenous antibiotic degradation","type":"exact"}],"termid":"GO:0042741"}


id: MONDO:0009036
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Pfeiffer-type cardiocranial syndrome is an extremely rare disorder recognized in less than ten patients worldwide and characterized by a congenital heart defect, sagittal craniosynostosis and severe developmental delay (growth retardation and intellectual deficit).","definition_xrefs":["Orphanet:2872"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"},{"relation_name":"is_a","term_name":"syndromic craniosynostosis","termid":"MONDO:0015338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"cardiocranial syndrome, Pfeiffer type","secondary_identifiers":["OMIM:218450","MESH:C535578","UMLS:C1857495","MEDGEN:346598","SCTID:720606005","icd11.foundation:629231429","GARD:8586"],"synonyms":[{"name":"Cardiocranial syndrome","type":"related"},{"name":"Pfeiffer Cardiocranial syndrome","type":"related"},{"name":"Pfeiffer Singer Zschiesche syndrome","type":"related"},{"name":"Pfeiffer-Singer-Zschiesche syndrome","type":"exact"},{"name":"Pfeiffer-type cardiocranial syndrome","type":"related"},{"name":"craniostenosis, sagittal, with congenital heart disease, mental deficiency, and mandibular ankylosis","type":"related"},{"name":"craniosynostosis-congenital heart disease-intellectual disability syndrome","type":"exact"},{"name":"sagittal craniostenosis with congenital heart disease, mental deficiency and mandibular ankylosis","type":"exact"}],"termid":"MONDO:0009036","xrefs":{"Monarch":{"xref_id":"0009036"}}}


id: PBO:0083282
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; partially overlaps the verified essential gene RRP14","termid":"PBO:0083282"}


id: GO:1905909
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of dauer entry.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:21531333"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of dauer larval development","termid":"GO:0061065"},{"relation_name":"regulates","term_name":"dauer entry","termid":"GO:0043053"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of dauer entry","synonyms":[{"name":"regulation of nematode entry into dormancy","type":"exact"}],"termid":"GO:1905909"}


id: PBO:0059190
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAS related GPR family member F","termid":"PBO:0059190"}


id: PBO:0080247
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vomeronasal 1 receptor 10 pseudogene","termid":"PBO:0080247"}


id: PBO:0046287
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EML4 antisense RNA 1","termid":"PBO:0046287"}


id: GO:0019318
data:
  {"annotated_genes":["SJAG_02135","SJAG_00461","SJAG_06622","SJAG_02945","SJAG_03336","SJAG_00839","SJAG_03828","SJAG_02369","SJAG_04334","SJAG_03660","SJAG_02009","SJAG_04192","SJAG_00605","SJAG_02950","SJAG_03373","SJAG_03822","SJAG_02107","SJAG_03903","SJAG_03370","SJAG_02951","SJAG_03743","SJAG_05006","SJAG_01402","SJAG_03818","SJAG_06621","SJAG_02796","SJAG_02148","SJAG_02713","SJAG_01414","SJAG_00134","SJAG_02297","SJAG_01310","SJAG_00240","SJAG_02954","SJAG_02783","SJAG_00027","SJAG_02596","SJAG_01784","SJAG_02696","SJAG_04495","SJAG_00039"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[109762,103983,109765,95352,109761,98324,105812,109760,103726,105811,109759,98595,109764,109763,94858,106181,116738,106182,105810,78197],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061621"},{"annotations":[68265,61309,70070,94859,63385],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006000"},{"annotations":[114097,114103,114115,114104],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033499"},{"annotations":[61858],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006012"},{"annotations":[59756,68430,116226,62744],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006006"},{"annotations":[99062,99061,115000,115001,88828],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0019655"},{"annotations":[76492,79483],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006013"},{"annotations":[96909],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:2001172"},{"annotations":[75468],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0010906"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.","definition_xrefs":["ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monosaccharide metabolic process","termid":"GO:0005996"}],"gene_count":41,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00039":null,"SJAG_00134":null,"SJAG_00240":null,"SJAG_00461":null,"SJAG_00605":null,"SJAG_00839":null,"SJAG_01310":null,"SJAG_01402":null,"SJAG_01414":null,"SJAG_01784":null,"SJAG_02009":null,"SJAG_02107":null,"SJAG_02135":null,"SJAG_02148":null,"SJAG_02297":null,"SJAG_02369":null,"SJAG_02596":null,"SJAG_02696":null,"SJAG_02713":null,"SJAG_02783":null,"SJAG_02796":null,"SJAG_02945":null,"SJAG_02950":null,"SJAG_02951":null,"SJAG_02954":null,"SJAG_03336":null,"SJAG_03370":null,"SJAG_03373":null,"SJAG_03660":null,"SJAG_03743":null,"SJAG_03818":null,"SJAG_03822":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04192":null,"SJAG_04334":null,"SJAG_04495":null,"SJAG_05006":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0005975"],"is_obsolete":false,"name":"hexose metabolic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"synonyms":[{"name":"hexose metabolism","type":"exact"}],"termid":"GO:0019318","terms_by_termid":{"GO:0006000":null,"GO:0006006":null,"GO:0006012":null,"GO:0006013":null,"GO:0010906":null,"GO:0019655":null,"GO:0033499":null,"GO:0061621":null,"GO:2001172":null}}


id: PBO:0061078
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"natural killer cell triggering receptor","termid":"PBO:0061078"}


id: PBO:0078836
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Pro (anticodon TGG) 2-1","termid":"PBO:0078836"}


id: MONDO:1012042
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"cerebellar abiotrophy, non-human animal","termid":"MONDO:1011834"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cerebellar abiotrophy, goat","secondary_identifiers":["OMIA:000175-9925"],"termid":"MONDO:1012042","xrefs":{"Monarch":{"xref_id":"1012042"}}}


id: PBO:0078304
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Asp (anticodon GTC) 2-9","termid":"PBO:0078304"}


id: PBO:0081383
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein 223","termid":"PBO:0081383"}


id: PR:000046670
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe sre2 gene.","definition_xrefs":["PRO:DAN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor sre2 (Schizosaccharomyces pombe)","pombase_gene_id":"SPBC354.05c","synonyms":[{"name":"Spom-sre2","type":"exact"},{"name":"sterol regulatory element-binding protein 2 (Schizosaccharomyces pombe)","type":"exact"}],"termid":"PR:000046670"}


id: GO:1903942
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:22819705"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of respiratory gaseous exchange","termid":"GO:0043576"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"positively_regulates","term_name":"respiratory gaseous exchange by respiratory system","termid":"GO:0007585"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of respiratory gaseous exchange","synonyms":[{"name":"activation of respiratory gaseous exchange","type":"narrow"},{"name":"up regulation of respiratory gaseous exchange","type":"exact"},{"name":"up-regulation of respiratory gaseous exchange","type":"exact"},{"name":"upregulation of respiratory gaseous exchange","type":"exact"}],"termid":"GO:1903942"}


id: GO:0031808
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a H2 histamine receptor.","definition_xrefs":["GOC:nln","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled histamine receptor binding","termid":"GO:0031806"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"H2 histamine receptor binding","synonyms":[{"name":"H2 histamine receptor ligand","type":"narrow"}],"termid":"GO:0031808"}


id: GO:0031628
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an opioid receptor.","definition_xrefs":["GOC:nln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor binding","termid":"GO:0001664"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005515","GO:0005488","GO:0003674"],"is_obsolete":false,"name":"opioid receptor binding","termid":"GO:0031628"}


id: PBO:0003486
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aromatic ring-opening dioxygenase (predicted)","termid":"PBO:0003486"}


id: MONDO:0008722
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Short-chain acyl-CoA dehydrogenase (SCAD) deficiency is a very rare inborn error of mitochondrial fatty acid oxidation characterized by variable manifestations ranging from asymptomatic individuals (in most cases) to those with failure to thrive, hypotonia, seizures, developmental delay and progressive myopathy.","definition_xrefs":["Orphanet:26792"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA dehydrogenase deficiency","termid":"MONDO:0017714"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0002525"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002525"],"is_obsolete":false,"name":"short chain acyl-CoA dehydrogenase deficiency","secondary_identifiers":["icd11.foundation:180018315","OMIM:201470","NANDO:2200514","GARD:4822","MEDGEN:90998","ICD10CM:E71.312","DOID:0080154","MESH:C537596","UMLS:C0342783","NCIT:C84539"],"synonyms":[{"name":"ACADS deficiency","type":"exact"},{"name":"ACADSD","type":"related"},{"name":"Acads deficiency","type":"related"},{"name":"SCAD","type":"exact"},{"name":"SCAD deficiency","type":"exact"},{"name":"SCADD","type":"exact"},{"name":"Scad deficiency","type":"related"},{"name":"Scadh deficiency","type":"related"},{"name":"Short Chain Acyl CoA Dehydrogenase Deficiency","type":"exact"},{"name":"acyl-CoA dehydrogenase, short-chain deficiency","type":"exact"},{"name":"acyl-CoA dehydrogenase, short-chain, deficiency OF","type":"related"},{"name":"lipid-storage myopathy secondary to short-chain acyl-Coa dehydrogenase deficiency","type":"related"},{"name":"short chain acyl-CoA dehydrogenase deficiency","type":"exact"},{"name":"short-chain acyl-CoA dehydrogenase deficiency","type":"related"},{"name":"short-chain acyl-CoA dehydrogenase deficiency (SCAD)","type":"exact"},{"name":"short-chain acyl-Coenzyme A dehydrogenase deficiency (SCAD)","type":"exact"},{"name":"short-chain acyl-coenzyme A dehydrogenase deficiency","type":"related"}],"termid":"MONDO:0008722","xrefs":{"Monarch":{"xref_id":"0008722"}}}


id: PBO:0035723
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_glycosylation_during_vegetative_growth","termid":"PBO:0035723"}


id: PBO:0075677
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spermatogenic leucine zipper 1","termid":"PBO:0075677"}


id: PBO:0077809
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tumor protein p53 regulated apoptosis inducing protein 1","termid":"PBO:0077809"}


id: GO:0170057
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H+.","definition_xrefs":["PMID:21311021","EC:6.5.1.8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA ligase activity","termid":"GO:0008452"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140098"},{"rel_name":"is_a","termid":"GO:0016874"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0140098","GO:0016874","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"RNA ligase (GTP) activity","synonyms":[{"name":"3'-phosphate/5'-hydroxy nucleic acid ligase activity","type":"exact"}],"termid":"GO:0170057"}


id: PBO:0001807
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"amino acid permease, unknown 3 (predicted)","termid":"PBO:0001807"}


id: PBO:0043168
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cartilage intermediate layer protein","termid":"PBO:0043168"}


id: GO:0019560
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-histidine catabolic process","termid":"GO:0006548"},{"relation_name":"is_a","term_name":"monocarboxylic acid metabolic process","termid":"GO:0032787"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006520"],"is_obsolete":false,"name":"histidine catabolic process to hydantoin-5-propionate","secondary_identifiers":["MetaCyc:HISHP-PWY"],"synonyms":[{"name":"histidine breakdown to hydantoin-5-propionate","type":"exact"},{"name":"histidine degradation to hydantoin-5-propionate","type":"exact"}],"termid":"GO:0019560"}


id: PBO:0047662
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FKBP14 antisense RNA 1","termid":"PBO:0047662"}


id: PBO:0082890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases; required for premeiotic DNA synthesis, expression of early and middle sporulation specific genes and direct phosphorylation of the Smk1p MAPK to regulate spore morphogenesis","termid":"PBO:0082890"}


id: GO:1902128
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol.","definition_xrefs":["PMID:15949826","PMID:9872995","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phenol-containing compound catabolic process","termid":"GO:0019336"},{"relation_name":"is_a","term_name":"lignan catabolic process","termid":"GO:0046273"},{"relation_name":"is_a","term_name":"(-)-lariciresinol metabolic process","termid":"GO:1902127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0008150"],"is_obsolete":false,"name":"(-)-lariciresinol catabolic process","synonyms":[{"name":"(-)-lariciresinol breakdown","type":"exact"},{"name":"(-)-lariciresinol catabolism","type":"exact"},{"name":"(-)-lariciresinol degradation","type":"exact"}],"termid":"GO:1902128"}


id: GO:0051152
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.","definition_xrefs":["CL:0000192","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of muscle cell differentiation","termid":"GO:0051149"},{"relation_name":"is_a","term_name":"regulation of smooth muscle cell differentiation","termid":"GO:0051150"},{"relation_name":"positively_regulates","term_name":"smooth muscle cell differentiation","termid":"GO:0051145"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of smooth muscle cell differentiation","synonyms":[{"name":"activation of smooth muscle cell differentiation","type":"narrow"},{"name":"stimulation of smooth muscle cell differentiation","type":"narrow"},{"name":"up regulation of smooth muscle cell differentiation","type":"exact"},{"name":"up-regulation of smooth muscle cell differentiation","type":"exact"},{"name":"upregulation of smooth muscle cell differentiation","type":"exact"}],"termid":"GO:0051152"}


id: PBO:0002101
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor Deb1/Rdp1","termid":"PBO:0002101"}


id: PBO:0003693
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by S. cerevisiae SNT309","termid":"PBO:0003693"}


id: MONDO:1010439
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cardiomyopathy that occurs in chicken.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bird disease","termid":"MONDO:0024905"},{"relation_name":"is_a","term_name":"cardiomyopathy, non-human animal","termid":"MONDO:1010010"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cardiomyopathy, chicken","secondary_identifiers":["OMIA:000160-9031"],"termid":"MONDO:1010439","xrefs":{"Monarch":{"xref_id":"1010439"}}}


id: GO:0030631
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases.","definition_xrefs":["PMID:11435424","PMID:17204561","RESID:AA0321"],"direct_ancestors":[{"relation_name":"is_a","term_name":"translational readthrough","termid":"GO:0006451"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"pyrrolysine incorporation","synonyms":[{"name":"lysine methylamine methyltransferase cofactor adduct incorporation","type":"exact"},{"name":"monomethylamine methyltransferase cofactor lysine adduct incorporation","type":"exact"}],"termid":"GO:0030631"}


id: PBO:0075038
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 116-1","termid":"PBO:0075038"}


id: PBO:0024804
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-enables_activity_in","termid":"PBO:0024804"}


id: PBO:0069372
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 632, pseudogene","termid":"PBO:0069372"}


id: PBO:0080987
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ZBTB20 antisense RNA 3","termid":"PBO:0080987"}


id: GO:0003759
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Assists in the correct, non-covalent assembly of glycoproteins in vivo, but is not a component of the assembled structures when performing its normal biological function. Utilizes a lectin site as a means to associate with the unfolded glycoproteins.","definition_xrefs":["GOC:jl","PMID:11337494"],"gene_count":0,"genotype_count":0,"name":"obsolete glycoprotein-specific chaperone activity (obsolete GO:0003759)","synonyms":[{"name":"glycoprotein-specific chaperone activity","type":"exact"}],"termid":"GO:0003759"}


id: PBO:0116792
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ciliated left-right organizer protein containing ZP-N domains","termid":"PBO:0116792"}


id: MOD:00308
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cyclizes an L-glutamine residue to form a carboxyl-terminal L-glutamimide.","definition_xrefs":["RESID:AA0303","PubMed:14593103","Unimod:23#Q","PubMed:12771378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cyclized residue","termid":"MOD:00601"},{"relation_name":"is_a","term_name":"dehydrated residue","termid":"MOD:00704"},{"relation_name":"is_a","term_name":"modified L-glutamine residue","termid":"MOD:00907"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-glutamimide","synonyms":[{"name":"(3S)-3-aminopiperidine-2,6-dione","type":"exact"},{"name":"2-aminopentanimide","type":"exact"},{"name":"3-amino-2,6-piperidinedione","type":"exact"},{"name":"Dehydrated","type":"related"},{"name":"Dehydration","type":"related"},{"name":"L-glutamimide","type":"exact"},{"name":"alpha-aminoglutarimide","type":"exact"}],"termid":"MOD:00308"}


id: PBO:0091716
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Multistep PhosphoRelay","termid":"PBO:0091716"}


id: PBO:0052444
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kruppel like factor 2 pseudogene 1","termid":"PBO:0052444"}


id: GO:0008923
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-lysine + H+ = cadaverine + CO2.","definition_xrefs":["RHEA:22352"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"lysine decarboxylase activity","secondary_identifiers":["EC:4.1.1.18","KEGG_REACTION:R00462","MetaCyc:LYSDECARBOX-RXN"],"synonyms":[{"name":"L-lysine carboxy-lyase activity","type":"related"}],"termid":"GO:0008923"}


id: MONDO:0040797
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. An outdated term to describe certain types of headache which were thought to be related to blood vessel swelling and hyperemia as cause of pain. it is no longer a recognized term and not mentioned in the Headache classification of the International Headache society (IHS).","definition_xrefs":["Wikipedia:Vascular_headache","PMID:3048700"],"gene_count":0,"genotype_count":0,"name":"obsolete vascular headache (obsolete MONDO:0040797)","secondary_identifiers":["MESH:D014653","SCTID:128187005"],"synonyms":[{"name":"vascular headache","type":"exact"}],"termid":"MONDO:0040797","xrefs":{"Monarch":{"xref_id":"0040797"}}}


id: MONDO:0019115
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Melanocortin 4 receptor (MC4R) deficiency is the commonest form of monogenic obesity identified so far. MC4R deficiency is characterized by severe obesity, an increase in lean body mass and bone mineral density, increased linear growth in early childhood, hyperphagia beginning in the first year of life and severe hyperinsulinaemia, in the presence of preserved reproductive function.","definition_xrefs":["Orphanet:71529"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited obesity","termid":"MONDO:0019182"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"obesity due to melanocortin 4 receptor deficiency","secondary_identifiers":["MEDGEN:903905","SCTID:717269008","NCIT:C120394","GARD:16690","UMLS:C4273958"],"synonyms":[{"name":"MC4R deficiency","type":"exact"}],"termid":"MONDO:0019115","xrefs":{"Monarch":{"xref_id":"0019115"}}}


id: GO:0102646
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol = all-trans-geranylfarnesol + H2O.","definition_xrefs":["GOC:pz","PMID:24200803"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydro-lyase activity","termid":"GO:0016836"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"14betaH-scalarane-17alpha-19-diol synthase activity","secondary_identifiers":["MetaCyc:RXN-15759"],"termid":"GO:0102646"}


id: PATO:0001093
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001093 relative flux value (obsolete PATO:0001093)","termid":"PATO:0001093"}


id: GO:0050682
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to an AF-2 protein domain, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.","definition_xrefs":["PMID:9682036"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein domain specific binding","termid":"GO:0019904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"AF-2 domain binding","termid":"GO:0050682"}


id: GO:0034380
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.","definition_xrefs":["GOC:BHF","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"plasma lipoprotein particle assembly","termid":"GO:0034377"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"high-density lipoprotein particle assembly","secondary_identifiers":["Reactome:R-HSA-8963896"],"synonyms":[{"name":"HDL assembly","type":"exact"}],"termid":"GO:0034380"}


id: PBO:0078593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tripartite motif containing 60 pseudogene 6, Y-linked","termid":"PBO:0078593"}


id: GO:0005746
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.","definition_xrefs":["GOC:ecd","ISBN:0198547684","GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete mitochondrial respirasome (obsolete GO:0005746)","synonyms":[{"name":"mitochondrial electron transport chain","type":"exact"},{"name":"mitochondrial respiratory chain","type":"exact"},{"name":"mitochondrial respiratory chain supercomplex","type":"exact"},{"name":"mitochondrial respiratory supercomplex","type":"exact"}],"termid":"GO:0005746"}


id: PBO:0087292
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Silencing protein; interacts with Sir2p, Sir4p, and histone H3/H4 tails to establish transcriptionally silent chromatin; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p; C-terminus assumes variant winged helix-turn-helix (wH) fold that mediates homodimerization, which is critical for holo-SIR complex loading; required for telomere hypercluster formation in quiescent yeast cells; has paralog ORC1 from whole genome duplication","termid":"PBO:0087292"}


id: PBO:0040839
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"B cell acute lymphoblastic leukemia expressed","termid":"PBO:0040839"}


id: MONDO:0017247
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital pulmonary sequestration","termid":"MONDO:0017843"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"communicating congenital bronchopulmonary-foregut malformation","secondary_identifiers":["UMLS:C0265790","Orphanet:280821","GARD:21092","MEDGEN:539496"],"termid":"MONDO:0017247","xrefs":{"Monarch":{"xref_id":"0017247"}}}


id: GO:0001659
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A homeostatic process in which an organism modulates its internal body temperature.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multicellular organismal-level homeostasis","termid":"GO:0048871"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"temperature homeostasis","secondary_identifiers":["Wikipedia:Thermoregulation"],"synonyms":[{"name":"thermoregulation","type":"exact"}],"termid":"GO:0001659"}


id: PBO:0077224
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane channel like 1","termid":"PBO:0077224"}


id: GO:1901851
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.","definition_xrefs":["PMID:14593448","GOC:TermGenie","GOC:yaf","UniPathway:UPA00072"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catabolic process","termid":"GO:0009056"},{"relation_name":"is_a","term_name":"7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process","termid":"GO:1901850"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process","synonyms":[{"name":"7,8-didemethyl-8-hydroxy-5-deazariboflavin breakdown","type":"exact"},{"name":"7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolism","type":"exact"},{"name":"7,8-didemethyl-8-hydroxy-5-deazariboflavin degradation","type":"exact"},{"name":"coenzyme F0 breakdown","type":"exact"},{"name":"coenzyme F0 catabolic process","type":"exact"},{"name":"coenzyme F0 catabolism","type":"exact"},{"name":"coenzyme F0 degradation","type":"exact"}],"termid":"GO:1901851"}


id: FYPO:0004616
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule depolymerization, i.e. the removal of tubulin dimers from a cytoplasmic microtubule, does not occur at the plus end of the microtubule at the cell tip. Normally, rapid depolymerization takes place when the growing plus end of the microtubule reaches the cell tip.","definition_xrefs":["GO:0070462","PMID:15772152","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal microtubule depolymerization during vegetative growth","termid":"FYPO:0000902"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000054","FYPO:0001320","FYPO:0005447","FYPO:0000002"],"is_obsolete":false,"name":"abolished cytoplasmic microtubule depolymerization at plus end at cell tip","synonyms":[{"name":"abolished cytoplasmic microtubule depolymerisation at plus end at cell tip","type":"exact"},{"name":"abolished cytoplasmic microtubule depolymerization at plus end at cell end","type":"exact"},{"name":"abolished cytoplasmic microtubule depolymerization at plus end at cell tip during mitotic cell cycle","type":"related"},{"name":"abolished cytoplasmic microtubule depolymerization at plus end at cell tip during vegetative growth","type":"exact"},{"name":"abolished microtubule catastrophe at cell tip","type":"related"},{"name":"abolished microtubule plus end shrinkage at cell tip","type":"related"},{"name":"abolished plus-end specific microtubule depolymerization at cell tip","type":"exact"},{"name":"cytoplasmic microtubule depolymerization at plus end at cell tip abolished","type":"exact"}],"termid":"FYPO:0004616"}


id: PBO:0053913
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1208","termid":"PBO:0053913"}


id: PBO:0005579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histone chaperone Cia1","termid":"PBO:0005579"}


id: PR:Q9UTA8
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC25B8.10 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UTA8"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized methyltransferase-like C25B8.10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC25B8.10","synonyms":[{"name":"Spom972h-SPAC25B8.10","type":"exact"}],"termid":"PR:Q9UTA8"}


id: PBO:0039667
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"adaptor related protein complex 3 subunit mu 2","termid":"PBO:0039667"}


id: PBO:0018063
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cytochrome c oxidase assembly protein Pet117 (predicted)","termid":"PBO:0018063"}


id: PBO:0001687
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"60S acidic ribosomal protein Rpp1-1","termid":"PBO:0001687"}


id: PBO:0049533
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H2A.Z histone pseudogene 4","termid":"PBO:0049533"}


id: GO:0047830
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.","definition_xrefs":["EC:1.5.1.11","MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"D-octopine dehydrogenase activity","secondary_identifiers":["RHEA:16285"],"synonyms":[{"name":"2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)","type":"related"},{"name":"D-octopine synthase activity","type":"related"},{"name":"N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)","type":"related"},{"name":"ODH activity","type":"related"},{"name":"octopine dehydrogenase activity","type":"related"},{"name":"octopine:NAD oxidoreductase activity","type":"related"}],"termid":"GO:0047830"}


id: PBO:0059770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-CO3 pseudogene 44","termid":"PBO:0059770"}


id: PBO:0066671
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RIPPLY3 pseudogene 1","termid":"PBO:0066671"}


id: GO:0000393
data:
  {"annotated_genes":["SJAG_01214","SJAG_01152","SJAG_01315","SJAG_02455","SJAG_01200","SJAG_02295","SJAG_00859","SJAG_04497","SJAG_01504"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[98344],"is_not":false,"summary":null,"term":"GO:0000393"},{"annotations":[106133,78262,58114],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000349"},{"annotations":[77673,73494,105205,109917],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000350"},{"annotations":[100974],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0000388"}]},"cv_name":"biological_process","definition":"Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-RNA complex assembly","termid":"GO:0022618"},{"relation_name":"part_of","term_name":"mRNA splicing, via spliceosome","termid":"GO:0000398"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00859":null,"SJAG_01152":null,"SJAG_01200":null,"SJAG_01214":null,"SJAG_01315":null,"SJAG_01504":null,"SJAG_02295":null,"SJAG_02455":null,"SJAG_04497":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0016071"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0065003","GO:0016071","GO:0008150","GO:0010467","GO:0044085"],"is_obsolete":false,"name":"spliceosomal conformational changes to generate catalytic conformation","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000104":null,"GO_REF:0000107":null},"synonyms":[{"name":"3'-splice site cleavage, exon ligation","type":"broad"}],"termid":"GO:0000393","terms_by_termid":{"GO:0000349":null,"GO:0000350":null,"GO:0000388":null,"GO:0000393":null}}


id: PBO:0084923
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters; required for removal of toxic metabolites in ethanol producing yeast cells; localizes to lipid particles and membranes; member of the eukaryotic serine hydrolase family; functional ortholog of mammalian MGL","termid":"PBO:0084923"}


id: GO:0071275
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to aluminum ion","termid":"GO:0010044"},{"relation_name":"is_a","term_name":"cellular response to metal ion","termid":"GO:0071248"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to aluminum ion","synonyms":[{"name":"cellular response to aluminium ion","type":"exact"},{"name":"cellular response to aluminum","type":"exact"}],"termid":"GO:0071275"}


id: GO:0050912
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detection of chemical stimulus involved in sensory perception","termid":"GO:0050907"},{"relation_name":"part_of","term_name":"sensory perception of taste","termid":"GO:0050909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"detection of chemical stimulus involved in sensory perception of taste","synonyms":[{"name":"perception of taste, detection of chemical stimulus","type":"exact"},{"name":"perception of taste, sensory detection of chemical stimulus","type":"exact"},{"name":"perception of taste, sensory transduction of chemical stimulus","type":"exact"},{"name":"sensory detection of chemical stimulus during perception of taste","type":"exact"},{"name":"sensory detection of taste","type":"exact"},{"name":"sensory transduction of chemical stimulus during perception of taste","type":"exact"},{"name":"sensory transduction of taste","type":"exact"},{"name":"taste perception","type":"broad"}],"termid":"GO:0050912"}


id: PBO:0048533
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GEMIN7 pseudogene 1","termid":"PBO:0048533"}


id: GO:0035034
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binds to and modulates the activity of histone acetyltransferase.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"enzyme regulator activity","termid":"GO:0030234"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0030234"}],"interesting_parent_ids":["GO:0098772","GO:0030234","GO:0003674"],"is_obsolete":false,"name":"histone acetyltransferase regulator activity","synonyms":[{"name":"histone acetylase regulator activity","type":"exact"}],"termid":"GO:0035034"}


id: PBO:0072630
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger and SPRY domain containing 1","termid":"PBO:0072630"}


id: PBO:0064639
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pro-platelet basic protein pseudogene 2","termid":"PBO:0064639"}


id: SO:0000715
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A motif that is active in RNA sequence.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide_motif","termid":"SO:0000714"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA_motif","synonyms":[{"name":"RNA motif","type":"exact"}],"termid":"SO:0000715"}


id: GO:0051560
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.","definition_xrefs":["GOC:mah","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular calcium ion homeostasis","termid":"GO:0006874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098771"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0098771","GO:0008150"],"is_obsolete":false,"name":"mitochondrial calcium ion homeostasis","synonyms":[{"name":"calcium ion homeostasis in mitochondria","type":"exact"},{"name":"calcium ion homeostasis in mitochondrion","type":"exact"},{"name":"mitochondrial calcium ion concentration regulation","type":"exact"},{"name":"regulation of calcium ion concentration in mitochondria","type":"exact"},{"name":"regulation of calcium ion concentration in mitochondrion","type":"exact"},{"name":"regulation of mitochondrial calcium ion concentration","type":"exact"}],"termid":"GO:0051560"}


id: PBO:0068909
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 152, pseudogene","termid":"PBO:0068909"}


id: GO:0005858
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.","definition_xrefs":["ISBN:0815316194","GOC:cilia","GOC:hla","GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dynein complex","termid":"GO:0030286"},{"relation_name":"part_of","term_name":"axoneme","termid":"GO:0005930"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0015630"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991","GO:0015630","GO:0005737"],"is_obsolete":false,"name":"axonemal dynein complex","synonyms":[{"name":"axonemal dynein heavy chain","type":"narrow"},{"name":"axonemal dynein intermediate chain","type":"narrow"},{"name":"axonemal dynein intermediate light chain","type":"narrow"},{"name":"axonemal dynein light chain","type":"narrow"}],"termid":"GO:0005858"}


id: PBO:0069246
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 501, pseudogene","termid":"PBO:0069246"}


id: GO:0097433
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An electron dense body which may contain granules.","definition_xrefs":["NIF_Subcellular:sao730872736","ISBN:0195065719"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"dense body","termid":"GO:0097433"}


id: PBO:0084595
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Merged open reading frame; does not encode a discrete protein; YJL017W was originally annotated as an independent ORF, but as a result of a sequence change, it was merged with an adjacent ORF into a single reading frame, designated YJL016W","termid":"PBO:0084595"}


id: PBO:0045680
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynein light chain LC8-type 1","termid":"PBO:0045680"}


id: MONDO:0034733
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A rare otorhinolaryngological malformation characterized by a hypoplastic or absent cochlear nerve, resulting in variable hearing loss or total deafness, depending on the quantity of nerve fibers present. The condition can be unilateral or bilateral, occur as an isolated malformation or in the context of a complex syndrome, and may be associated with a hypoplastic internal auditory or cochlear nerve canal. [Orphanet:502318]","definition_xrefs":["Orphanet:502318"],"gene_count":0,"genotype_count":0,"name":"obsolete cochlear nerve deficiency (obsolete MONDO:0034733)","secondary_identifiers":["ICD10CM:H93.3"],"termid":"MONDO:0034733","xrefs":{"Monarch":{"xref_id":"0034733"}}}


id: PBO:0086316
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with similarity to ABC transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance","termid":"PBO:0086316"}


id: MONDO:0006410
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A proliferation of endometrial cells resulting in glandular enlargement and budding without changes in the basic structure of the endometrium. Epithelial atypia may be present or absent.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hyperplasia","termid":"MONDO:0005043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"simple endometrial hyperplasia","secondary_identifiers":["NCIT:C35463","UMLS:C0456483","SCTID:198324001","ICD9:621.31","EFO:1000525","MEDGEN:96819"],"termid":"MONDO:0006410","xrefs":{"Monarch":{"xref_id":"0006410"}}}


id: MONDO:0002161
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete fallopian tube carcinosarcoma (obsolete MONDO:0002161)","termid":"MONDO:0002161","xrefs":{"Monarch":{"xref_id":"0002161"}}}


id: GO:1905013
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from L-tryptophan.","definition_xrefs":["PMID:12140278","PMID:19843166","GOC:bf","GOC:PARL","GOC:TermGenie","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of amine metabolic process","termid":"GO:0033239"},{"relation_name":"is_a","term_name":"negative regulation of amino acid metabolic process","termid":"GO:0045763"},{"relation_name":"is_a","term_name":"negative regulation of purine nucleotide biosynthetic process","termid":"GO:1900372"},{"relation_name":"is_a","term_name":"negative regulation of NAD metabolic process","termid":"GO:1902689"},{"relation_name":"is_a","term_name":"regulation of 'de novo' NAD biosynthetic process from L-tryptophan","termid":"GO:1905012"},{"relation_name":"negatively_regulates","term_name":"'de novo' NAD+ biosynthetic process from L-tryptophan","termid":"GO:0034354"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"negatively_regulates","termid":"GO:0055086"},{"rel_name":"regulates","termid":"GO:0055086"},{"rel_name":"negatively_regulates","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0055086","GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"negative regulation of 'de novo' NAD biosynthetic process from L-tryptophan","synonyms":[{"name":"down regulation of 'de novo' NAD biosynthetic process from tryptophan","type":"exact"},{"name":"down regulation of de novo NAD biosynthetic process from tryptophan","type":"related"},{"name":"down-regulation of 'de novo' NAD biosynthetic process from tryptophan","type":"exact"},{"name":"down-regulation of de novo NAD biosynthetic process from tryptophan","type":"related"},{"name":"downregulation of 'de novo' NAD biosynthetic process from tryptophan","type":"exact"},{"name":"downregulation of de novo NAD biosynthetic process from tryptophan","type":"related"},{"name":"inhibition of 'de novo' NAD biosynthetic process from tryptophan","type":"narrow"},{"name":"inhibition of de novo NAD biosynthetic process from tryptophan","type":"related"},{"name":"negative regulation of 'de novo' NAD biosynthetic process from tryptophan","type":"broad"},{"name":"negative regulation of de novo NAD biosynthetic process from tryptophan","type":"related"}],"termid":"GO:1905013"}


id: GO:0046068
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine ribonucleotide metabolic process","termid":"GO:0009150"},{"relation_name":"is_a","term_name":"cyclic purine nucleotide metabolic process","termid":"GO:0052652"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0008150","GO:0055086","GO:0044281"],"is_obsolete":false,"name":"cGMP metabolic process","synonyms":[{"name":"cGMP metabolism","type":"exact"}],"termid":"GO:0046068"}


id: PBO:0072045
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S10 pseudogene 15","termid":"PBO:0072045"}


id: PBO:0066204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA binding motif protein 18","termid":"PBO:0066204"}


id: FYPO:0002156
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and one septum, and in which the septum is located between the two nuclei but is not perpendicular to the long axis of the cell.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"binucleate vegetative cell","termid":"FYPO:0001222"},{"relation_name":"is_a","term_name":"misoriented septum during vegetative growth","termid":"FYPO:0001390"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"binucleate monoseptate cell, with angled septum","synonyms":[{"name":"binucleate monoseptate cell, with angled septum during mitotic cell cycle","type":"related"},{"name":"binucleate monoseptate cell, with angled septum, during vegetative growth","type":"exact"},{"name":"binucleate monoseptate cell, with septum not orthogonal to long axis","type":"related"}],"termid":"FYPO:0002156"}


id: PBO:0091647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane amino acid transmembrane transporter Aat1","termid":"PBO:0091647"}


id: FYPO:0006784
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which vacuoles tubule-shaped.","definition_xrefs":["PMID:30451685","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vacuolar morphology during vegetative growth","termid":"FYPO:0000368"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"tubular vacuole morphology during vegetative growth","synonyms":[{"name":"tubular vacuole morphology during mitotic cell cycle","type":"related"},{"name":"tubular-shaped vacuoles during vegetative growth","type":"exact"}],"termid":"FYPO:0006784"}


id: PBO:0072092
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S12 pseudogene 23","termid":"PBO:0072092"}


