# terms

id: PATO:0002406
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Easily reduced to powder or easily fragmentable or crumbly.","definition_xrefs":["PATOC:MPATH"],"direct_ancestors":[{"relation_name":"is_a","term_name":"friability","termid":"PATO:0002405"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"friable","termid":"PATO:0002406"}


id: GO:0140738
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An inflammasome complex that consists of NLRP6, PYCARD/ASC and caspase-1 or caspase-4/caspase-11.","definition_xrefs":["PMID:30674671","PMID:34678144"],"direct_ancestors":[{"relation_name":"is_a","term_name":"canonical inflammasome complex","termid":"GO:0061702"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0032991"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005829"}],"interesting_parent_ids":["GO:0005737","GO:0032991","GO:0005575","GO:0005829"],"is_obsolete":false,"name":"NLRP6 inflammasome complex","termid":"GO:0140738"}


id: PBO:0050424
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterogeneous nuclear ribonucleoprotein H1 pseudogene 3","termid":"PBO:0050424"}


id: MONDO:0021043
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm composed of at least two distinct cellular populations.","definition_xrefs":["NCIT:C6930"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplasm","termid":"MONDO:0005070"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mixed neoplasm","secondary_identifiers":["MESH:D018193","UMLS:C1368354","ICDO:8940/1","MEDGEN:234575"],"synonyms":[{"name":"mixed neoplasm","type":"exact"},{"name":"mixed tumor","type":"exact"},{"name":"mixed tumour","type":"exact"}],"termid":"MONDO:0021043","xrefs":{"Monarch":{"xref_id":"0021043"}}}


id: GO:0047803
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.","definition_xrefs":["MetaCyc:CYSTEINE-LYASE-RXN","EC:4.4.1.10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbon-sulfur lyase activity","termid":"GO:0016846"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016829","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"cysteine lyase activity","secondary_identifiers":["RHEA:20916"],"synonyms":[{"name":"L-cysteine hydrogen-sulfide-lyase (adding sulfite)","type":"related"},{"name":"L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming)","type":"related"},{"name":"cysteine (sulfite) lyase activity","type":"related"}],"termid":"GO:0047803"}


id: GO:1904084
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epiboly.","definition_xrefs":["GO_REF:0000058","PMID:24892953","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of epiboly (obsolete GO:1904084)","synonyms":[{"name":"down regulation of epiboly","type":"exact"},{"name":"down-regulation of epiboly","type":"exact"},{"name":"downregulation of epiboly","type":"exact"},{"name":"inhibition of epiboly","type":"narrow"},{"name":"negative regulation of epiboly","type":"exact"}],"termid":"GO:1904084"}


id: PBO:0085063
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Non-essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and translocation into the ER; other members are Sec63p, Sec62p, and Sec66p","termid":"PBO:0085063"}


id: GO:0051647
data:
  {"annotated_genes":["SJAG_02431","SJAG_02286","SJAG_00594","SJAG_03264","SJAG_00397","SJAG_00113","SJAG_01662","SJAG_00140","SJAG_02737","SJAG_02509","SJAG_04001","SJAG_02561","SJAG_01370","SJAG_03673","SJAG_02651","SJAG_05185","SJAG_03073","SJAG_04143","SJAG_00368","SJAG_04387","SJAG_01297","SJAG_01863","SJAG_02045","SJAG_01613","SJAG_04003","SJAG_03835","SJAG_04597"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[110204],"is_not":false,"summary":null,"term":"GO:0051647"},{"annotations":[113013,104867,118933,102617,99452,89566,115922,97070,105158,113364,92822,93683,93218],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030989"},{"annotations":[113187,108518,103331],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0032118"},{"annotations":[106457,114739,106789],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0007097"},{"annotations":[76783,72521,115924,109363,103342,111561,118937],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098863"},{"annotations":[99527,101111],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0090561"},{"annotations":[89570,93220,101112,78097,99454],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000743"},{"annotations":[96261],"is_not":false,"rel_names":["positively_regulates","regulates"],"summary":null,"term":"GO:1902854"}]},"cv_name":"biological_process","definition":"Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organelle localization","termid":"GO:0051640"}],"gene_count":27,"genes_by_uniquename":{"SJAG_00113":null,"SJAG_00140":null,"SJAG_00368":null,"SJAG_00397":null,"SJAG_00594":null,"SJAG_01297":null,"SJAG_01370":null,"SJAG_01613":null,"SJAG_01662":null,"SJAG_01863":null,"SJAG_02045":null,"SJAG_02286":null,"SJAG_02431":null,"SJAG_02509":null,"SJAG_02561":null,"SJAG_02651":null,"SJAG_02737":null,"SJAG_03073":null,"SJAG_03264":null,"SJAG_03673":null,"SJAG_03835":null,"SJAG_04001":null,"SJAG_04003":null,"SJAG_04143":null,"SJAG_04387":null,"SJAG_04597":null,"SJAG_05185":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0008150"],"is_obsolete":false,"name":"nucleus localization","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"cell nucleus localization","type":"exact"},{"name":"establishment and maintenance of nucleus localization","type":"exact"},{"name":"localization of nucleus","type":"exact"},{"name":"nucleus localisation","type":"exact"}],"termid":"GO:0051647","terms_by_termid":{"GO:0000743":null,"GO:0007097":null,"GO:0030989":null,"GO:0032118":null,"GO:0051647":null,"GO:0090561":null,"GO:0098863":null,"GO:1902854":null}}


id: PBO:0070977
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L19 pseudogene 1","termid":"PBO:0070977"}


id: GO:0047603
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: acetoacetyl-CoA + H2O = acetoacetate + CoA + H+.","definition_xrefs":["EC:3.1.2.11","RHEA:15673"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA hydrolase activity","termid":"GO:0016289"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"}],"interesting_parent_ids":["GO:0016787","GO:0016788","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"acetoacetyl-CoA hydrolase activity","secondary_identifiers":["KEGG_REACTION:R01358","MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN"],"synonyms":[{"name":"acetoacetyl CoA deacylase activity","type":"related"},{"name":"acetoacetyl coenzyme A deacylase activity","type":"related"},{"name":"acetoacetyl coenzyme A hydrolase activity","type":"related"}],"termid":"GO:0047603"}


id: PBO:0054601
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2005","termid":"PBO:0054601"}


id: GO:1901186
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.","definition_xrefs":["GOC:TermGenie","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of signal transduction","termid":"GO:0009967"},{"relation_name":"is_a","term_name":"regulation of ERBB signaling pathway","termid":"GO:1901184"},{"relation_name":"positively_regulates","term_name":"ERBB signaling pathway","termid":"GO:0038127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"positive regulation of ERBB signaling pathway","synonyms":[{"name":"activation of EGF receptor family signaling pathway","type":"exact"},{"name":"activation of EGFR family signaling pathway","type":"related"},{"name":"activation of ERBB signaling pathway","type":"narrow"},{"name":"activation of ERBB signalling pathway","type":"exact"},{"name":"activation of ErbB signaling","type":"exact"},{"name":"positive regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"positive regulation of EGFR family signaling pathway","type":"related"},{"name":"positive regulation of ERBB signalling pathway","type":"exact"},{"name":"positive regulation of ErbB signaling","type":"exact"},{"name":"up regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"up regulation of EGFR family signaling pathway","type":"related"},{"name":"up regulation of ERBB signaling pathway","type":"exact"},{"name":"up regulation of ERBB signalling pathway","type":"exact"},{"name":"up regulation of ErbB signaling","type":"exact"},{"name":"up-regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"up-regulation of EGFR family signaling pathway","type":"related"},{"name":"up-regulation of ERBB signaling pathway","type":"exact"},{"name":"up-regulation of ERBB signalling pathway","type":"exact"},{"name":"up-regulation of ErbB signaling","type":"exact"},{"name":"upregulation of EGF receptor family signaling pathway","type":"exact"},{"name":"upregulation of EGFR family signaling pathway","type":"related"},{"name":"upregulation of ERBB signaling pathway","type":"exact"},{"name":"upregulation of ERBB signalling pathway","type":"exact"},{"name":"upregulation of ErbB signaling","type":"exact"}],"termid":"GO:1901186"}


id: PR:O94461
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC1687.21 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94461"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatase C1687.21 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1687.21","synonyms":[{"name":"Spom972h-SPAC1687.21","type":"exact"}],"termid":"PR:O94461"}


id: GO:0034769
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.","definition_xrefs":["PMID:17301221","GOC:sart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extracellular matrix disassembly","termid":"GO:0022617"},{"relation_name":"is_a","term_name":"basement membrane organization","termid":"GO:0071711"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"basement membrane disassembly","secondary_identifiers":["GO:0060881"],"synonyms":[{"name":"basal lamina disassembly","type":"related"}],"termid":"GO:0034769"}


id: PR:Q09173
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ptc3 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q09173"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 2C homolog 3 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC2G11.07c","synonyms":[{"name":"PP2C-3 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-ptc3","type":"exact"}],"termid":"PR:Q09173"}


id: GO:0034506
data:
  {"annotated_genes":["SJAG_03220","SJAG_03183","SJAG_03449","SJAG_03491","SJAG_00768","SJAG_03832","SJAG_00307","SJAG_04038","SJAG_00170","SJAG_00207","SJAG_01050","SJAG_03126","SJAG_03567","SJAG_00684","SJAG_00646","SJAG_01745","SJAG_02778","SJAG_01332","SJAG_01082"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[72278,89805,90890,91505,108113,112259,113639,115347,116467,118449],"is_not":false,"summary":null,"term":"GO:0034506"},{"annotations":[119139,113911,118502,93162,93903,108224,91881,111609],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0061638"},{"annotations":[103956],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0043505"}]},"cv_name":"cellular_component","definition":"The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.","definition_xrefs":["GOC:mah","GOC:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosomal region","termid":"GO:0098687"},{"relation_name":"part_of","term_name":"chromosome, centromeric region","termid":"GO:0000775"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00170":null,"SJAG_00207":null,"SJAG_00307":null,"SJAG_00646":null,"SJAG_00684":null,"SJAG_00768":null,"SJAG_01050":null,"SJAG_01082":null,"SJAG_01332":null,"SJAG_01745":null,"SJAG_02778":null,"SJAG_03126":null,"SJAG_03183":null,"SJAG_03220":null,"SJAG_03449":null,"SJAG_03491":null,"SJAG_03567":null,"SJAG_03832":null,"SJAG_04038":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005694","GO:0005575"],"is_obsolete":false,"name":"chromosome, centromeric core domain","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"chromosome, centric core region","type":"related"},{"name":"chromosome, centromeric core region","type":"exact"}],"termid":"GO:0034506","terms_by_termid":{"GO:0034506":null,"GO:0043505":null,"GO:0061638":null}}


id: PBO:0082540
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance","termid":"PBO:0082540"}


id: PBO:0090284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Prp19 complex subunit Prp45","termid":"PBO:0090284"}


id: PBO:0018285
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein implicated in autophagy Ctl1","termid":"PBO:0018285"}


id: GO:0006828
data:
  {"annotated_genes":["SJAG_04096","SJAG_03850","SJAG_01007","SJAG_04867"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[62161,65022,110610,72532],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071421"}]},"cv_name":"biological_process","definition":"The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transition metal ion transport","termid":"GO:0000041"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01007":null,"SJAG_03850":null,"SJAG_04096":null,"SJAG_04867":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"manganese ion transport","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"termid":"GO:0006828","terms_by_termid":{"GO:0071421":null}}


id: PBO:0041180
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"butyrophilin subfamily 3 member A2","termid":"PBO:0041180"}


id: GO:0072718
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to chemical","termid":"GO:0042221"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to cisplatin","termid":"GO:0072718"}


id: PBO:0073575
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"shisa family member 6","termid":"PBO:0073575"}


id: FYPO:0005439
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of DNA/DNA annealing activity is decreased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased catalytic activity","termid":"FYPO:0000663"},{"relation_name":"is_a","term_name":"abnormal DNA/DNA annealing activity","termid":"FYPO:0005438"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000653"}],"interesting_parent_ids":["FYPO:0000661","FYPO:0000652","FYPO:0000707","FYPO:0000653","FYPO:0001985","FYPO:0000654"],"is_obsolete":false,"name":"decreased DNA/DNA annealing activity","synonyms":[{"name":"reduced DNA/DNA annealing activity","type":"exact"}],"termid":"FYPO:0005439"}


id: PBO:0077942
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ala (anticodon AGC) 2-2","termid":"PBO:0077942"}


id: MONDO:0007021
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Allergic reaction to wheat that is triggered by the immune system.","definition_xrefs":["EFO:1001243"],"gene_count":0,"genotype_count":0,"name":"obsolete wheat allergic disease (obsolete MONDO:0007021)","secondary_identifiers":["MESH:D021182","ICD9:995.3","SCTID:420174000","DOID:3660"],"synonyms":[{"name":"allergic disease from wheat based food product","type":"exact"},{"name":"allergy of wheat based food product","type":"exact"},{"name":"allergy to wheat","type":"exact"},{"name":"wheat allergic reaction","type":"related"},{"name":"wheat allergy","type":"related"},{"name":"wheat based food product allergic disease","type":"exact"}],"termid":"MONDO:0007021","xrefs":{"Monarch":{"xref_id":"0007021"}}}


id: GO:0075713
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"establishment of viral latency","termid":"GO:0019043"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"establishment of integrated proviral latency","secondary_identifiers":["GO:0019047","VZ:980","Reactome:R-HSA-162592"],"synonyms":[{"name":"prophage integration","type":"exact"},{"name":"provirus integration","type":"exact"}],"termid":"GO:0075713"}


id: GO:1905429
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.","definition_xrefs":["GO_REF:0000071","PMID:18984164","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to amino acid","termid":"GO:0043200"},{"relation_name":"is_a","term_name":"response to nitrogen compound","termid":"GO:1901698"},{"relation_name":"is_a","term_name":"response to oxygen-containing compound","termid":"GO:1901700"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to glycine","synonyms":[{"name":"response to Gly","type":"exact"},{"name":"response to aminoacetic acid","type":"exact"},{"name":"response to aminoethanoic acid","type":"exact"},{"name":"response to glycin","type":"exact"}],"termid":"GO:1905429"}


id: MONDO:0016712
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Classic medulloblastoma is a histological variant of medulloblastoma, an embryonic malignancy, having a midline location, occurring most often in children and manifesting with variable symptoms such as headaches, nausea, vomiting and ataxia.","definition_xrefs":["Orphanet:251867"],"direct_ancestors":[{"relation_name":"is_a","term_name":"medulloblastoma","termid":"MONDO:0007959"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"classic medulloblastoma","secondary_identifiers":["GARD:17216","NCIT:C54039","SCTID:699704002","UMLS:C1707400","icd11.foundation:1548011794","MEDGEN:353541"],"synonyms":[{"name":"classic medulloblastoma","type":"exact"}],"termid":"MONDO:0016712","xrefs":{"Monarch":{"xref_id":"0016712"}}}


id: PBO:0109380
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"testis expressed transcript, Y-linked 11","termid":"PBO:0109380"}


id: PBO:0039841
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho GTPase activating protein 11A","termid":"PBO:0039841"}


id: PBO:0042887
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cilia and flagella associated protein 300","termid":"PBO:0042887"}


id: MONDO:0018791
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. A rare cerebral vasculopathy characterized by a progressive stenosis of the terminal portion of the internal carotid arteries and the development of abnormal collateral vessels.","definition_xrefs":["PMID:32089044"],"gene_count":0,"genotype_count":0,"name":"obsolete Moyomoya angiopathy (obsolete MONDO:0018791)","secondary_identifiers":["Orphanet:477768"],"termid":"MONDO:0018791","xrefs":{"Monarch":{"xref_id":"0018791"}}}


id: PBO:0085806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; down-regulated at low calcium levels; mCherry fusion protein localizes to the vacuole","termid":"PBO:0085806"}


id: GO:0016677
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on a heme group of donors","termid":"GO:0016675"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor","secondary_identifiers":["EC:1.9.6.-"],"synonyms":[{"name":"oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor","type":"exact"}],"termid":"GO:0016677"}


id: GO:1905196
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATPase activity, uncoupled.","definition_xrefs":["GOC:TermGenie","GO_REF:0000059","PMID:26545917"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of ATPase activity, uncoupled (obsolete GO:1905196)","synonyms":[{"name":"activation of ATPase activity, uncoupled","type":"narrow"},{"name":"activation of adenylpyrophosphatase activity","type":"related"},{"name":"positive regulation of adenylpyrophosphatase activity","type":"related"},{"name":"up regulation of ATPase activity, uncoupled","type":"exact"},{"name":"up regulation of adenylpyrophosphatase activity","type":"related"},{"name":"up-regulation of ATPase activity, uncoupled","type":"exact"},{"name":"up-regulation of adenylpyrophosphatase activity","type":"related"},{"name":"upregulation of ATPase activity, uncoupled","type":"exact"},{"name":"upregulation of adenylpyrophosphatase activity","type":"related"}],"termid":"GO:1905196"}


id: PBO:0047562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FGF14 antisense RNA 1","termid":"PBO:0047562"}


id: PBO:0045547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dual specificity phosphatase 2","termid":"PBO:0045547"}


id: SO:1001270
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:1001270 stop_codon_redefinition_as_pyrrolysine (obsolete SO:1001270)","termid":"SO:1001270"}


id: PATO:0002523
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A positional quality inhering in a bearer by virtue of the bearer's being located at a right angle relative to another entity and to the horizon.","definition_xrefs":["PATOC:EJS"],"direct_ancestors":[{"relation_name":"is_a","term_name":"position","termid":"PATO:0000140"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vertical to","termid":"PATO:0002523"}


id: PBO:0075934
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ST20 antisense RNA 1","termid":"PBO:0075934"}


id: PBO:0002490
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-amylase homolog Aah2 (predicted)","termid":"PBO:0002490"}


id: PBO:0085746
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in yeast cell wall biogenesis; localizes to the cell periphery; production of Nag1p is dependent upon the presence of Slt2p and Rlm1p; gene is nested within and antisense to IMO32","termid":"PBO:0085746"}


id: GO:0010515
data:
  {"annotated_genes":["SJAG_04312","SJAG_02444","SJAG_02592","SJAG_01311","SJAG_04026","SJAG_02723","SJAG_02773","SJAG_01254","SJAG_00526","SJAG_00975","SJAG_01699","SJAG_00472","SJAG_02266","SJAG_01084","SJAG_02730","SJAG_03081","SJAG_00600"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90018,93242,94769,96073,96215,102430,103745,106411,107732,107830,108425,108579,108775,110960,116449,117516,118052],"is_not":false,"summary":null,"term":"GO:0010515"}]},"cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of conjugation with cellular fusion","termid":"GO:0031138"},{"relation_name":"negatively_regulates","term_name":"induction of conjugation with cellular fusion","termid":"GO:0010514"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00472":null,"SJAG_00526":null,"SJAG_00600":null,"SJAG_00975":null,"SJAG_01084":null,"SJAG_01254":null,"SJAG_01311":null,"SJAG_01699":null,"SJAG_02266":null,"SJAG_02444":null,"SJAG_02592":null,"SJAG_02723":null,"SJAG_02730":null,"SJAG_02773":null,"SJAG_03081":null,"SJAG_04026":null,"SJAG_04312":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0000747"},{"rel_name":"negatively_regulates","termid":"GO:0000747"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0000747"],"is_obsolete":false,"name":"negative regulation of induction of conjugation with cellular fusion","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0010515","terms_by_termid":{"GO:0010515":null}}


id: FYPO:0003927
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell population phenotype in which a smaller than normal proportion of cells in the population is viable when double-strand breaks in DNA are continually made (for example, by constitutive expression of a nuclease).","definition_xrefs":["PomBase:mah","PMID:22093869"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell population viability","termid":"FYPO:0002057"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002057"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002057"],"is_obsolete":false,"name":"decreased population viability in presence of persistent double-strand breaks","synonyms":[{"name":"decreased frequency of HO survivors","type":"narrow"},{"name":"decreased population viability in presence of nuclease","type":"related"},{"name":"reduced population viability in presence of persistent double-strand breaks","type":"exact"}],"termid":"FYPO:0003927"}


id: PBO:0058225
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4515","termid":"PBO:0058225"}


id: PBO:0068528
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U1 small nuclear 129, pseudogene","termid":"PBO:0068528"}


id: PBO:0002368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterised trans-sulfuration enzyme (predicted)","termid":"PBO:0002368"}


id: PBO:0030039
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_fatty_acid_synthase_activity","termid":"PBO:0030039"}


id: GO:1900541
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of fumonisin.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secondary metabolite biosynthetic process","termid":"GO:0044550"},{"relation_name":"is_a","term_name":"carboxylic acid biosynthetic process","termid":"GO:0046394"},{"relation_name":"is_a","term_name":"fumonisin metabolic process","termid":"GO:1900539"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0044281","GO:0019748","GO:0008150"],"is_obsolete":false,"name":"fumonisin biosynthetic process","synonyms":[{"name":"fumonisin anabolism","type":"exact"},{"name":"fumonisin biosynthesis","type":"exact"},{"name":"fumonisin formation","type":"exact"},{"name":"fumonisin synthesis","type":"exact"}],"termid":"GO:1900541"}


id: MONDO:0011449
data:
  {"annotated_genes":["SJAG_05182","SJAG_04706","SJAG_02139","SJAG_04295","SJAG_05175"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87177,87178,87179,87180,87181],"is_not":false,"summary":null,"term":"MONDO:0011449"}]},"cv_name":"mondo","definition":"Salla disease is the mildest form of the free sialic acid storage disorders, which primarily affect the nervous system. Infants with Salla disease typically begin to experience poor muscle tone (hypotonia) during the first year of life,followed by slowly progressive neurological problems. Signs and symptoms include intellectual disability and developmental delay; seizures ; ataxia ; muscle spasticity; and involuntary slow movements of the limbs (athetosis). About one-third of affected children learn to walk. It is caused by mutations in the SLC17A5 gene and is inherited in an autosomal recessive manner. Treatment is generally symptomatic and supportive.","direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of carbohydrate transmembrane transport and absorption","termid":"MONDO:0017706"},{"relation_name":"is_a","term_name":"free sialic acid storage disease","termid":"MONDO:0019366"}],"gene_count":5,"genes_by_uniquename":{"SJAG_02139":null,"SJAG_04295":null,"SJAG_04706":null,"SJAG_05175":null,"SJAG_05182":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0002561","MONDO:0037792"],"is_obsolete":false,"name":"Salla disease","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:604369","MEDGEN:203368","NANDO:2201294","SCTID:87074006","UMLS:C1096903","NANDO:1200149","GARD:4754","NANDO:1200582","NCIT:C85067","Orphanet:309334","MedDRA:10067531"],"synonyms":[{"name":"SD","type":"related"},{"name":"Salla disease","type":"exact"},{"name":"sialic acid storage disease","type":"exact"},{"name":"sialuria, Finnish type","type":"related"}],"termid":"MONDO:0011449","terms_by_termid":{"MONDO:0011449":null},"xrefs":{"Monarch":{"xref_id":"0011449"}}}


id: GO:0090234
data:
  {"annotated_genes":["SJAG_00718","SJAG_03048","SJAG_01837","SJAG_04638"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[119942],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905560"},{"annotations":[118660,104273,91474],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905561"}]},"cv_name":"biological_process","definition":"Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.","definition_xrefs":["GOC:ascb_2009","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of centromere complex assembly","termid":"GO:0090230"},{"relation_name":"is_a","term_name":"regulation of organelle assembly","termid":"GO:1902115"},{"relation_name":"regulates","term_name":"kinetochore assembly","termid":"GO:0051382"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00718":null,"SJAG_01837":null,"SJAG_03048":null,"SJAG_04638":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0065003"}],"interesting_parent_ids":["GO:0008150","GO:0044085","GO:0065003"],"is_obsolete":false,"name":"regulation of kinetochore assembly","references_by_uniquename":{"GO_REF:0000107":null},"secondary_identifiers":["GO:1901719"],"synonyms":[{"name":"regulation of NMS complex assembly","type":"narrow"},{"name":"regulation of chromosome-kinetochore attachment","type":"narrow"}],"termid":"GO:0090234","terms_by_termid":{"GO:1905560":null,"GO:1905561":null}}


id: PBO:0065617
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase 4A3","termid":"PBO:0065617"}


id: PBO:0080084
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin specific peptidase 46","termid":"PBO:0080084"}


id: PBO:0068411
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ring finger protein, transmembrane 1 pseudogene 2","termid":"PBO:0068411"}


id: GO:1900600
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving endocrocin.","definition_xrefs":["GOC:di","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phenol-containing compound metabolic process","termid":"GO:0018958"},{"relation_name":"is_a","term_name":"secondary metabolic process","termid":"GO:0019748"},{"relation_name":"is_a","term_name":"carboxylic acid metabolic process","termid":"GO:0019752"},{"relation_name":"is_a","term_name":"ketone metabolic process","termid":"GO:0042180"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0019748","GO:0008150"],"is_obsolete":false,"name":"endocrocin metabolic process","synonyms":[{"name":"endocrocin metabolism","type":"exact"}],"termid":"GO:1900600"}


id: GO:0052842
data:
  {"annotated_genes":["SJAG_01154","SJAG_00244","SJAG_04870"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[58611,90539,107121],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052843"},{"annotations":[90540,107122],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052845"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate.","definition_xrefs":["PMID:10827188","PMID:11502751"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diphosphoinositol-polyphosphate diphosphatase activity","termid":"GO:0008486"}],"gene_count":3,"genes_by_uniquename":{"SJAG_00244":null,"SJAG_01154":null,"SJAG_04870":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016787"],"is_obsolete":false,"name":"inositol diphosphate pentakisphosphate diphosphatase activity","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000117":null},"secondary_identifiers":["Reactome:R-HSA-2023971","Reactome:R-HSA-1855198"],"termid":"GO:0052842","terms_by_termid":{"GO:0052843":null,"GO:0052845":null}}


id: PR:O14049
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 40S ribosomal protein S8 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO01779"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"40S ribosomal protein S8-A (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC2C4.16c","secondary_identifiers":["UniProtKB:O14049"],"synonyms":[{"name":"Spom972h-RPS8","type":"exact"}],"termid":"PR:O14049"}


id: GO:1902818
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving ethyl acetate.","definition_xrefs":["PMID:16013377","GOC:mengo_curators","GOC:TermGenie","GO_REF:0000068"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acetate ester metabolic process","termid":"GO:1900619"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ethyl acetate metabolic process","synonyms":[{"name":"ethyl acetate metabolism","type":"exact"},{"name":"ethyl ethanoate metabolic process","type":"exact"}],"termid":"GO:1902818"}


id: GO:0047662
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.","definition_xrefs":["EC:4.1.1.24","MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"aminobenzoate decarboxylase activity","secondary_identifiers":["RHEA:24200"],"synonyms":[{"name":"aminobenzoate carboxy-lyase (aniline-forming)","type":"related"},{"name":"aminobenzoate carboxy-lyase activity","type":"related"}],"termid":"GO:0047662"}


id: PBO:0060717
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NDUFA6 divergent transcript","termid":"PBO:0060717"}


id: PBO:0054521
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1921","termid":"PBO:0054521"}


id: FYPO:0006616
data:
  {"alleles_by_uniquename":{"SJAG_00028:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_00028","name":"rga6delta","uniquename":"SJAG_00028:allele-1"},"SJAG_04522:allele-1":{"allele_type":"deletion","description":"deletion","gene_uniquename":"SJAG_04522","name":"rga4delta","uniquename":"SJAG_04522:allele-1"}},"annotation_feature_type":"genotype","cv_annotations":{"single_locus_phenotype":[{"annotations":[121546,121547],"is_not":false,"summary":null,"term":"FYPO:0006616"}]},"cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and has a diameter greater than normal. Cell volume may or may not be increased.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"increased cell diameter","termid":"FYPO:0006615"},{"relation_name":"is_a","term_name":"viable cell","termid":"FYPO:0000124"},{"relation_name":"is_a","term_name":"abnormal vegetative cell shape","termid":"FYPO:0002196"},{"relation_name":"is_a","term_name":"increased cell diameter","termid":"FYPO:0006615"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00028":null,"SJAG_04522":null},"genotype_count":2,"genotypes_by_uniquename":{"rga4delta":{"display_name":"rga4delta","display_uniquename":"rga4delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_04522:allele-1","expression":"Null"}]}]},"rga6delta":{"display_name":"rga6delta","display_uniquename":"rga6delta","loci":[{"expressed_alleles":[{"allele_uniquename":"SJAG_00028:allele-1","expression":"Null"}]}]}},"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"has_part","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000004","FYPO:0000005","FYPO:0000002"],"is_obsolete":false,"name":"viable vegetative cell with increased cell diameter","references_by_uniquename":{"PMID:30664646":null},"single_locus_annotated_genes":["SJAG_04522","SJAG_00028"],"single_locus_genotype_uniquenames":["rga4delta","rga6delta"],"synonyms":[{"name":"viable cell with increased cell diameter during vegetative growth","type":"exact"},{"name":"viable vegetative cell with increased cell diameter during mitotic cell cycle","type":"related"},{"name":"viable vegetative cell with increased cell thickness","type":"exact"},{"name":"viable vegetative cell with increased cell width","type":"exact"}],"termid":"FYPO:0006616","terms_by_termid":{"FYECO:0000005":null,"FYECO:0000137":null,"FYPO:0006616":null,"FYPO_EXT:0000001":null,"FYPO_EXT:0000002":null}}


id: PBO:0086330
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein with WD-40 repeats involved in rRNA processing; associates with rDNA chromatin in H4-tail-dependent manner; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily","termid":"PBO:0086330"}


id: FYPO:0002786
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which occurrence of riboflavin binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal riboflavin binding","termid":"FYPO:0002388"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000707"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000652","FYPO:0000707"],"is_obsolete":false,"name":"decreased riboflavin binding","synonyms":[{"name":"reduced riboflavin binding","type":"exact"}],"termid":"FYPO:0002786"}


id: PBO:0047386
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box protein 24","termid":"PBO:0047386"}


id: PR:G2TRR0
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPBC336.16 gene.","definition_xrefs":["PRO:DNx","UniProtKB:G2TRR0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C336.16 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC336.16","synonyms":[{"name":"Spom972h-SPBC336.16","type":"exact"}],"termid":"PR:G2TRR0"}


id: MONDO:0001054
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"pterygium","termid":"MONDO:0005085"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"double pterygium","secondary_identifiers":["MEDGEN:509817","ICD9:372.44","UMLS:C0155157","SCTID:41564009","DOID:10525"],"termid":"MONDO:0001054","xrefs":{"Monarch":{"xref_id":"0001054"}}}


id: GO:0072151
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell fate commitment","termid":"GO:0045165"},{"relation_name":"part_of","term_name":"mesangial cell differentiation","termid":"GO:0072007"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesangial cell fate commitment","termid":"GO:0072151"}


id: GO:0016155
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 10-formyltetrahydrofolate + H2O + NADP+ = (6S)-5,6,7,8-tetrahydrofolate + CO2 + H+ + NADPH.","definition_xrefs":["RHEA:10180","EC:1.5.1.6"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor","termid":"GO:0016646"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"formyltetrahydrofolate dehydrogenase activity","secondary_identifiers":["KEGG_REACTION:R00941","MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN"],"synonyms":[{"name":"10-formyl tetrahydrofolate:NADP oxidoreductase activity","type":"related"},{"name":"10-formyl-H2PtGlu:NADP oxidoreductase activity","type":"related"},{"name":"10-formyl-H4folate dehydrogenase activity","type":"related"},{"name":"10-formyltetrahydrofolate dehydrogenase activity","type":"related"},{"name":"10-formyltetrahydrofolate:NADP+ oxidoreductase activity","type":"related"},{"name":"N10-formyltetrahydrofolate dehydrogenase activity","type":"related"}],"termid":"GO:0016155"}


id: PBO:0049615
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H3 histone pseudogene 18","termid":"PBO:0049615"}


id: PBO:0078952
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Arg (anticodon TCT) 3-2","termid":"PBO:0078952"}


id: PBO:0074337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2","termid":"PBO:0074337"}


id: GO:1905258
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.","definition_xrefs":["PMID:14752510","GOC:PARL","GOC:TermGenie","GOC:bf","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of cellular response to stress","termid":"GO:0080135"},{"relation_name":"is_a","term_name":"regulation of intrinsic apoptotic signaling pathway","termid":"GO:2001242"},{"relation_name":"regulates","term_name":"intrinsic apoptotic signaling pathway in response to nitrosative stress","termid":"GO:1990442"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway","synonyms":[{"name":"regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress","type":"exact"},{"name":"regulation of nitrosative stress-induced apoptosis","type":"related"}],"termid":"GO:1905258"}


id: PBO:0083734
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential chromatin-associated protein; involved in initiation of DNA replication; required for association of MCM2-7 complex with replication origins; required to stabilize catalytic subunit of DNA polymerase-alpha; coordinates function of replication fork helicase; self-associates through its N-terminal domain","termid":"PBO:0083734"}


id: PBO:0072416
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S27 pseudogene 21","termid":"PBO:0072416"}


id: MONDO:0020860
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Infection of the fauces by Corynebacterium diphtheriae.","definition_xrefs":["NCIT:C34545"],"direct_ancestors":[{"relation_name":"is_a","term_name":"diphtheria","termid":"MONDO:0005504"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"faucial diphtheria","secondary_identifiers":["MEDGEN:3857","SCTID:3419005","UMLS:C0012556","ICD9:032.0"],"synonyms":[{"name":"Diphtheritic membrane","type":"related"},{"name":"Diphtheritic membranous angina","type":"related"},{"name":"Faucial Diphtheria","type":"related"},{"name":"Faucial diphtheria","type":"related"},{"name":"diphtheritic membrane","type":"related"},{"name":"diphtheritic membranous angina","type":"related"},{"name":"faucial diphtheria","type":"exact"}],"termid":"MONDO:0020860","xrefs":{"Monarch":{"xref_id":"0020860"}}}


id: FYPO:0007751
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but does not elongate normally or completely, and collapses during prometaphase I. Upon collapse the spindle may break or shrink.","definition_xrefs":["PomBase:mah","PMID:32723864"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spindle collapse during meiosis I","termid":"FYPO:0007103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0000631","FYPO:0001985"],"is_obsolete":false,"name":"spindle collapse during meiotic prometaphase I","synonyms":[{"name":"broken meiotic spindle during prometaphase I","type":"related"},{"name":"meiosis I spindle collapse during prometaphase","type":"exact"},{"name":"meiotic spindle breakage during prometaphase I","type":"exact"},{"name":"meiotic spindle collapse during prometaphase I","type":"exact"},{"name":"spindle collapse during prometaphase I","type":"exact"},{"name":"spindle collapse during prometaphase of meiosis I","type":"exact"}],"termid":"FYPO:0007751"}


id: PBO:0068647
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U4 small nuclear 28, pseudogene","termid":"PBO:0068647"}


id: PBO:0030160
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_chromatin_during_vegetative_growth","termid":"PBO:0030160"}


id: GO:1900834
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of emericellin biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of xanthone-containing compound biosynthetic process","termid":"GO:1900183"},{"relation_name":"is_a","term_name":"regulation of secondary metabolite biosynthetic process","termid":"GO:1900376"},{"relation_name":"regulates","term_name":"emericellin biosynthetic process","termid":"GO:1900766"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0019748"},{"rel_name":"regulates","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0044281","GO:0019748","GO:0008150"],"is_obsolete":false,"name":"regulation of emericellin biosynthetic process","synonyms":[{"name":"regulation of Variecoxanthone B anabolism","type":"related"},{"name":"regulation of Variecoxanthone B biosynthesis","type":"related"},{"name":"regulation of Variecoxanthone B biosynthetic process","type":"related"},{"name":"regulation of Variecoxanthone B formation","type":"related"},{"name":"regulation of Variecoxanthone B synthesis","type":"related"},{"name":"regulation of emericellin anabolism","type":"exact"},{"name":"regulation of emericellin biosynthesis","type":"exact"},{"name":"regulation of emericellin formation","type":"exact"},{"name":"regulation of emericellin synthesis","type":"exact"}],"termid":"GO:1900834"}


id: PBO:0056345
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAP4K3 divergent transcript","termid":"PBO:0056345"}


id: GO:0030500
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of bone mineralization.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of ossification","termid":"GO:0030278"},{"relation_name":"is_a","term_name":"regulation of biomineral tissue development","termid":"GO:0070167"},{"relation_name":"regulates","term_name":"bone mineralization","termid":"GO:0030282"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of bone mineralization","termid":"GO:0030500"}


id: PBO:0064188
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phospholipase A2 group XIIA pseudogene 2","termid":"PBO:0064188"}


id: MONDO:0043183
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"podder-tolmie syndrome","secondary_identifiers":["MEDGEN:419827","MESH:C537518","UMLS:C2931519"],"synonyms":[{"name":"meningoencephalocele, arthrogryposis and hypoplastic thumbs","type":"related"}],"termid":"MONDO:0043183","xrefs":{"Monarch":{"xref_id":"0043183"}}}


id: GO:0102091
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = an 1-phosphatidyl-1D-myo-inositol + phosphate.","definition_xrefs":["PMID:12878591","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylinositol monophosphate phosphatase activity","termid":"GO:0052744"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016787","GO:0003824","GO:0016788"],"is_obsolete":false,"name":"phosphatidylinositol-5-phosphate phosphatase activity","secondary_identifiers":["MetaCyc:RXN-10962"],"synonyms":[{"name":"phosphatidylinositol-5-phosphate 5-phosphatase activity","type":"exact"}],"termid":"GO:0102091"}


id: GO:0010764
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.","definition_xrefs":["GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of fibroblast migration","termid":"GO:0010762"},{"relation_name":"is_a","term_name":"negative regulation of cell migration","termid":"GO:0030336"},{"relation_name":"negatively_regulates","term_name":"fibroblast migration","termid":"GO:0010761"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of fibroblast migration","synonyms":[{"name":"negative regulation of fibroblast cell migration","type":"exact"}],"termid":"GO:0010764"}


id: PBO:0084404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Lysine-specific metalloprotease of the pitrilysin family; metalloprotease of the intermembrane space; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology; mutation in human homolog PITRM1 is implicated in autosomal recessive spinocerebellar ataxias (ARCA)","termid":"PBO:0084404"}


id: PBO:0001482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoadenosine phosphosulfate reductase","termid":"PBO:0001482"}


id: PBO:0004638
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial iron sulfur cluster assembly protein Isd11 (predicted)","termid":"PBO:0004638"}


id: GO:1902277
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion.","definition_xrefs":["GOC:TermGenie","GOC:jc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of protein secretion","termid":"GO:0050709"},{"relation_name":"is_a","term_name":"regulation of pancreatic amylase secretion","termid":"GO:1902276"},{"relation_name":"negatively_regulates","term_name":"pancreatic amylase secretion","termid":"GO:0036395"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"},{"rel_name":"negatively_regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"negative regulation of pancreatic amylase secretion","synonyms":[{"name":"down regulation of pancreatic amylase secretion","type":"exact"},{"name":"down-regulation of pancreatic amylase secretion","type":"exact"},{"name":"downregulation of pancreatic amylase secretion","type":"exact"},{"name":"inhibition of pancreatic amylase secretion","type":"narrow"}],"termid":"GO:1902277"}


id: GO:0052237
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete aerotaxis in other organism involved in symbiotic interaction (obsolete GO:0052237)","synonyms":[{"name":"aerotaxis in other organism during symbiotic interaction","type":"related"},{"name":"aerotaxis within other organism during symbiotic interaction","type":"exact"}],"termid":"GO:0052237"}


id: MONDO:0033135
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare autosomal dominant hereditary demyelinating motor and sensory neuropathy characterized by progressive distal muscle weakness and atrophy, distal sensory impairment, and decreased or absent reflexes in the affected limbs, with an onset in the first or second decade of life. Median motor nerve conduction velocities are typically less than 38 m/s. Patients often have foot deformities. Sural nerve biopsy shows decrease in myelinated fibers, myelin abnormalities, and onion bulb formation. Fatty replacement of muscle tissue predominantly affects the anterior and lateral compartment of the lower legs.","definition_xrefs":["Orphanet:476394"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease","termid":"MONDO:0015626"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease, demyelinating, type 1G","secondary_identifiers":["DOID:0111560","GARD:17851","OMIM:618279","UMLS:C4748940","MEDGEN:1648290"],"synonyms":[{"name":"CMT1G","type":"exact"},{"name":"Charcot-Marie-Tooth disease, demyelinating, type 1G","type":"exact"},{"name":"PMP2-related Charcot-Marie-Tooth disease type 1","type":"exact"}],"termid":"MONDO:0033135","xrefs":{"Monarch":{"xref_id":"0033135"}}}


id: PBO:0027229
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_fatty_acid","termid":"PBO:0027229"}


id: PBO:0089389
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"V-type ATPase V0 subunit c''","termid":"PBO:0089389"}


id: MONDO:0009953
data:
  {"annotated_genes":["SJAG_01960"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87431],"is_not":false,"summary":null,"term":"MONDO:0009953"}]},"cv_name":"mondo","definition":"Leukocyte adhesion deficiency type II (LAD-II) is a form of LAD characterized by recurrent bacterial infections, severe growth delay and severe intellectual deficit.","definition_xrefs":["Orphanet:99843"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital disorder of glycosylation type II","termid":"MONDO:0005501"},{"relation_name":"is_a","term_name":"congenital hematological disorder","termid":"MONDO:0009332"},{"relation_name":"is_a","term_name":"leukocyte adhesion deficiency","termid":"MONDO:0017570"},{"relation_name":"is_a","term_name":"disorder of multiple glycosylation","termid":"MONDO:0017749"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01960":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0024322","MONDO:0006025","MONDO:0005046","MONDO:0005066"],"is_obsolete":false,"name":"leukocyte adhesion deficiency type II","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0080492","SCTID:234583001","MESH:C535755","DOID:0070255","GARD:4634","NCIT:C4690","UMLS:C0398739","OMIM:266265","MEDGEN:96022"],"synonyms":[{"name":"CDG 2C","type":"related"},{"name":"CDG IIc","type":"exact"},{"name":"CDG syndrome type IIc","type":"exact"},{"name":"CDG-IIc","type":"exact"},{"name":"CDG2C","type":"exact"},{"name":"CDGIIc","type":"exact"},{"name":"LAD-II","type":"exact"},{"name":"LAD2","type":"exact"},{"name":"RHS","type":"exact"},{"name":"Rambam-Hasharon syndrome","type":"exact"},{"name":"SLC35C1-CDG","type":"exact"},{"name":"SLC35C1-CDG (CDG-IIc)","type":"related"},{"name":"congenital disorder of glycosylation type IIC","type":"related"},{"name":"congenital disorder of glycosylation, type IIc","type":"related"},{"name":"lad-II","type":"exact"},{"name":"lad-type II","type":"exact"},{"name":"leukocyte adhesion deficiency type 2","type":"exact"},{"name":"leukocyte adhesion deficiency type II","type":"exact"},{"name":"leukocyte adhesion deficiency, type 2","type":"related"},{"name":"leukocyte adhesion deficiency, type II","type":"exact"},{"name":"sialyl-Lewis X defect","type":"exact"}],"termid":"MONDO:0009953","terms_by_termid":{"MONDO:0009953":null},"xrefs":{"Monarch":{"xref_id":"0009953"}}}


id: MONDO:0019502
data:
  {"annotated_genes":["SJAG_03286","SJAG_01570","SJAG_02042","SJAG_02099","SJAG_01465","SJAG_03333","SJAG_04321","SJAG_01070","SJAG_03032","SJAG_04640","SJAG_01702","SJAG_04084","SJAG_03635","SJAG_04358","SJAG_00898","SJAG_01536","SJAG_01625","SJAG_01991","SJAG_03448","SJAG_01826","SJAG_04119","SJAG_04704","SJAG_00886","SJAG_04645","SJAG_04654","SJAG_03147","SJAG_02717","SJAG_00325"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87449],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0100255"},{"annotations":[86937],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014648"},{"annotations":[86901],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0040500"},{"annotations":[88082],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032662"},{"annotations":[87860],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032665"},{"annotations":[88767],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032789"},{"annotations":[88902],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030533"},{"annotations":[88217],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957288"},{"annotations":[88903],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0958204"},{"annotations":[88302],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013173"},{"annotations":[87760],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013528"},{"annotations":[88212],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014348"},{"annotations":[88101],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014409"},{"annotations":[88895,88896],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012613"},{"annotations":[86938],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014649"},{"annotations":[87632],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014815"},{"annotations":[88958],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014930"},{"annotations":[88824],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014996"},{"annotations":[88668],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0015020"},{"annotations":[88506],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0044313"},{"annotations":[88154,88155,88156],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0020850"},{"annotations":[88897],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0012615"},{"annotations":[88124],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013853"},{"annotations":[88714],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014485"},{"annotations":[87619],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013624"}]},"cv_name":"mondo","definition":"Autosomal recessive form of non-syndromic intellectual disability.","definition_xrefs":["MONDO:patterns/autosomal_recessive"],"direct_ancestors":[{"relation_name":"is_a","term_name":"non-syndromic intellectual disability","termid":"MONDO:0000509"},{"relation_name":"is_a","term_name":"disorder of carbohydrate transmembrane transport and absorption","termid":"MONDO:0017706"},{"relation_name":"is_a","term_name":"intellectual disability, autosomal recessive","termid":"MONDO:0100597"}],"gene_count":28,"genes_by_uniquename":{"SJAG_00325":null,"SJAG_00886":null,"SJAG_00898":null,"SJAG_01070":null,"SJAG_01465":null,"SJAG_01536":null,"SJAG_01570":null,"SJAG_01625":null,"SJAG_01702":null,"SJAG_01826":null,"SJAG_01991":null,"SJAG_02042":null,"SJAG_02099":null,"SJAG_02717":null,"SJAG_03032":null,"SJAG_03147":null,"SJAG_03286":null,"SJAG_03333":null,"SJAG_03448":null,"SJAG_03635":null,"SJAG_04084":null,"SJAG_04119":null,"SJAG_04321":null,"SJAG_04358":null,"SJAG_04640":null,"SJAG_04645":null,"SJAG_04654":null,"SJAG_04704":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0037792","MONDO:0006025"],"is_obsolete":false,"name":"autosomal recessive non-syndromic intellectual disability","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:88616","OMIMPS:249500","UMLS:C5680181","MEDGEN:1826073","DOID:0060308","GARD:18643"],"synonyms":[{"name":"AR-NSID","type":"exact"},{"name":"NS-ARID","type":"exact"},{"name":"autosomal recessive intellectual disability","type":"broad"},{"name":"autosomal recessive mental retardation","type":"exact"},{"name":"autosomal recessive non-syndromic intellectual disability","type":"exact"},{"name":"autosomal recessive non-syndromic mental retardation","type":"exact"},{"name":"intellectual disability, autosomal recessive","type":"broad"},{"name":"mental retardation, autosomal recessive","type":"exact"},{"name":"non-syndromic intellectual disability, autosomal recessive","type":"exact"}],"termid":"MONDO:0019502","terms_by_termid":{"MONDO:0012613":null,"MONDO:0012615":null,"MONDO:0013173":null,"MONDO:0013528":null,"MONDO:0013624":null,"MONDO:0013853":null,"MONDO:0014348":null,"MONDO:0014409":null,"MONDO:0014485":null,"MONDO:0014648":null,"MONDO:0014649":null,"MONDO:0014815":null,"MONDO:0014930":null,"MONDO:0014996":null,"MONDO:0015020":null,"MONDO:0020850":null,"MONDO:0030533":null,"MONDO:0032662":null,"MONDO:0032665":null,"MONDO:0032789":null,"MONDO:0040500":null,"MONDO:0044313":null,"MONDO:0100255":null,"MONDO:0957288":null,"MONDO:0958204":null},"xrefs":{"Monarch":{"xref_id":"0019502"}}}


id: GO:0051127
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of actin nucleation","termid":"GO:0051125"},{"relation_name":"is_a","term_name":"positive regulation of cytoskeleton organization","termid":"GO:0051495"},{"relation_name":"is_a","term_name":"positive regulation of supramolecular fiber organization","termid":"GO:1902905"},{"relation_name":"positively_regulates","term_name":"actin nucleation","termid":"GO:0045010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0030036"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"positively_regulates","termid":"GO:0007010"}],"interesting_parent_ids":["GO:0030036","GO:0008150","GO:0007010"],"is_obsolete":false,"name":"positive regulation of actin nucleation","synonyms":[{"name":"activation of actin nucleation","type":"narrow"},{"name":"stimulation of actin nucleation","type":"narrow"},{"name":"up regulation of actin nucleation","type":"exact"},{"name":"up-regulation of actin nucleation","type":"exact"},{"name":"upregulation of actin nucleation","type":"exact"}],"termid":"GO:0051127"}


id: PBO:0047660
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FKBP prolyl isomerase 11","termid":"PBO:0047660"}


id: PBO:0062991
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphofurin acidic cluster sorting protein 2","termid":"PBO:0062991"}


id: PBO:0066928
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 230","termid":"PBO:0066928"}


id: PBO:0076228
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPT16 homolog, facilitates chromatin remodeling subunit pseudogene 1","termid":"PBO:0076228"}


id: GO:0120009
data:
  {"annotated_genes":["SJAG_04370","SJAG_03247","SJAG_03416","SJAG_02375","SJAG_03746","SJAG_05268","SJAG_01229","SJAG_03338","SJAG_03710","SJAG_16459","SJAG_00230","SJAG_03718","SJAG_03721","SJAG_02323","SJAG_01590","SJAG_00355","SJAG_01329","SJAG_03741","SJAG_00576","SJAG_01305","SJAG_03851","SJAG_03172","SJAG_01225","SJAG_01722"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[57358],"is_not":false,"summary":null,"term":"GO:0120009"},{"annotations":[99429,99363,91051,102416,107770,118225,108669,109579,111476,105946,109454,100504,92730,103174,110594],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120010"},{"annotations":[96090,110144,118203,111314,93316,104511,108256,113291],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0120011"}]},"cv_name":"biological_process","definition":"The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).","definition_xrefs":["GOC:krc","PMID:24220498","PMID:20823909","PMID:25797198"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipid transport","termid":"GO:0006869"},{"relation_name":"is_a","term_name":"membrane organization","termid":"GO:0061024"}],"gene_count":24,"genes_by_uniquename":{"SJAG_00230":null,"SJAG_00355":null,"SJAG_00576":null,"SJAG_01225":null,"SJAG_01229":null,"SJAG_01305":null,"SJAG_01329":null,"SJAG_01590":null,"SJAG_01722":null,"SJAG_02323":null,"SJAG_02375":null,"SJAG_03172":null,"SJAG_03247":null,"SJAG_03338":null,"SJAG_03416":null,"SJAG_03710":null,"SJAG_03718":null,"SJAG_03721":null,"SJAG_03741":null,"SJAG_03746":null,"SJAG_03851":null,"SJAG_04370":null,"SJAG_05268":null,"SJAG_16459":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0061024","GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"intermembrane lipid transfer","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000108":null},"termid":"GO:0120009","terms_by_termid":{"GO:0120009":null,"GO:0120010":null,"GO:0120011":null}}


id: PBO:0116309
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"conserved fungal protein, possible MARVEL domain, implicated in membrane organization","termid":"PBO:0116309"}


id: MONDO:0017378
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete polymicrogyria-turricephaly-hypogenitalism syndrome (obsolete MONDO:0017378)","secondary_identifiers":["Orphanet:2925"],"termid":"MONDO:0017378","xrefs":{"Monarch":{"xref_id":"0017378"}}}


id: PBO:0077603
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transmembrane serine protease 11E","termid":"PBO:0077603"}


id: MONDO:0020467
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"monosomy X","termid":"MONDO:0020466"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005047"}],"interesting_parent_ids":["MONDO:0005047"],"is_obsolete":false,"name":"mosaic monosomy X","secondary_identifiers":["GARD:19677","SCTID:710010005","MEDGEN:873772","Orphanet:99228","UMLS:C4040907"],"synonyms":[{"name":"Mosaic Turner syndrome","type":"exact"},{"name":"Mosaic monosomy type X","type":"exact"},{"name":"XX/XO","type":"exact"}],"termid":"MONDO:0020467","xrefs":{"Monarch":{"xref_id":"0020467"}}}


id: GO:0061903
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.","definition_xrefs":["GOC:aruk","GOC:bc","PMID:18723082"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of 1-phosphatidylinositol-3-kinase activity (obsolete GO:0061903)","termid":"GO:0061903"}


id: GO:0004159
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.","definition_xrefs":["PMID:23150645"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","termid":"GO:0016628"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"dihydropyrimidine dehydrogenase (NAD+) activity","secondary_identifiers":["EC:1.3.1.1","MetaCyc:DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN"],"synonyms":[{"name":"5,6-dihydrouracil:NAD+ oxidoreductase activity","type":"related"},{"name":"dihydrothymine dehydrogenase (NAD+) activity","type":"narrow"},{"name":"dihydrouracil dehydrogenase (NAD+) activity","type":"narrow"},{"name":"pyrimidine reductase activity","type":"related"},{"name":"thymine reductase activity","type":"narrow"},{"name":"uracil reductase activity","type":"narrow"}],"termid":"GO:0004159"}


id: GO:0071649
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of chemokine production","termid":"GO:0032642"},{"relation_name":"regulates","term_name":"chemokine (C-C motif) ligand 5 production","termid":"GO:0071609"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0010467","GO:0008150"],"is_obsolete":false,"name":"regulation of chemokine (C-C motif) ligand 5 production","synonyms":[{"name":"regulation of CCL5 production","type":"exact"},{"name":"regulation of RANTES production","type":"exact"},{"name":"regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production","type":"exact"}],"termid":"GO:0071649"}


id: PBO:0083825
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential subunit of the Dam1 complex (aka DASH complex); couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases; sumoylated in an Mms21p-dependent manner; protein abundance increases in response to DNA replication stress","termid":"PBO:0083825"}


id: GO:0005029
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete CD27 receptor activity (obsolete GO:0005029)","synonyms":[{"name":"CD27 receptor activity","type":"exact"}],"termid":"GO:0005029"}


id: PBO:0056288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MANEAL pseudogene 1","termid":"PBO:0056288"}


id: GO:0046669
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of retinal cell programmed cell death","termid":"GO:0046668"},{"relation_name":"regulates","term_name":"compound eye retinal cell programmed cell death","termid":"GO:0046667"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of compound eye retinal cell programmed cell death","synonyms":[{"name":"regulation of retinal cell programmed cell death","type":"broad"}],"termid":"GO:0046669"}


id: PBO:0063166
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PAX3 and PAX7 binding protein 1","termid":"PBO:0063166"}


id: GO:1901185
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.","definition_xrefs":["GOC:BHF","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of signal transduction","termid":"GO:0009968"},{"relation_name":"is_a","term_name":"regulation of ERBB signaling pathway","termid":"GO:1901184"},{"relation_name":"negatively_regulates","term_name":"ERBB signaling pathway","termid":"GO:0038127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of ERBB signaling pathway","synonyms":[{"name":"down regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"down regulation of EGFR family signaling pathway","type":"related"},{"name":"down regulation of ERBB signaling pathway","type":"exact"},{"name":"down regulation of ERBB signalling pathway","type":"exact"},{"name":"down regulation of ErbB signaling","type":"exact"},{"name":"down-regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"down-regulation of EGFR family signaling pathway","type":"related"},{"name":"down-regulation of ERBB signaling pathway","type":"exact"},{"name":"down-regulation of ERBB signalling pathway","type":"exact"},{"name":"down-regulation of ErbB signaling","type":"exact"},{"name":"downregulation of EGF receptor family signaling pathway","type":"exact"},{"name":"downregulation of EGFR family signaling pathway","type":"related"},{"name":"downregulation of ERBB signaling pathway","type":"exact"},{"name":"downregulation of ERBB signalling pathway","type":"exact"},{"name":"downregulation of ErbB signaling","type":"exact"},{"name":"inhibition of EGF receptor family signaling pathway","type":"exact"},{"name":"inhibition of EGFR family signaling pathway","type":"related"},{"name":"inhibition of ERBB signaling pathway","type":"narrow"},{"name":"inhibition of ERBB signalling pathway","type":"exact"},{"name":"inhibition of ErbB signaling","type":"exact"},{"name":"negative regulation of EGF receptor family signaling pathway","type":"exact"},{"name":"negative regulation of EGFR family signaling pathway","type":"related"},{"name":"negative regulation of ERBB signalling pathway","type":"exact"},{"name":"negative regulation of ErbB signaling","type":"exact"}],"termid":"GO:1901185"}


id: MONDO:0958030
data:
  {"annotated_genes":["SJAG_00912"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87842],"is_not":false,"summary":null,"term":"MONDO:0958030"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"immunodeficiency disease","termid":"MONDO:0021094"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00912":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"immunodeficiency 118","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:1852539","OMIM:301115","UMLS:C5882665"],"termid":"MONDO:0958030","terms_by_termid":{"MONDO:0958030":null},"xrefs":{"Monarch":{"xref_id":"0958030"}}}


id: GO:0060697
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.","definition_xrefs":["GOC:BHF","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of lipid catabolic process","termid":"GO:0050996"},{"relation_name":"is_a","term_name":"regulation of phospholipid catabolic process","termid":"GO:0060696"},{"relation_name":"is_a","term_name":"positive regulation of phospholipid metabolic process","termid":"GO:1903727"},{"relation_name":"positively_regulates","term_name":"phospholipid catabolic process","termid":"GO:0009395"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006629"},{"rel_name":"positively_regulates","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"positive regulation of phospholipid catabolic process","termid":"GO:0060697"}


id: PBO:0059494
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"macrophage stimulating 1 receptor","termid":"PBO:0059494"}


id: PBO:0110232
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Pseudo HisTone","termid":"PBO:0110232"}


id: MONDO:0013064
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any multiple synostoses syndrome in which the cause of the disease is a mutation in the FGF9 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multiple synostoses syndrome","termid":"MONDO:0017923"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"multiple synostoses syndrome 3","secondary_identifiers":["MESH:C567839","GARD:15597","DOID:0081319","OMIM:612961","MEDGEN:414116","UMLS:C2751826"],"synonyms":[{"name":"FGF9 multiple synostoses syndrome","type":"exact"},{"name":"SYNS3","type":"related"},{"name":"multiple synostoses syndrome 3","type":"exact"},{"name":"multiple synostoses syndrome caused by mutation in FGF9","type":"exact"},{"name":"multiple synostoses syndrome type 3","type":"exact"}],"termid":"MONDO:0013064","xrefs":{"Monarch":{"xref_id":"0013064"}}}


id: GO:0110083
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.","definition_xrefs":["GOC:vw","PMID:29343550"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of cell cycle process","termid":"GO:0090068"},{"relation_name":"is_a","term_name":"regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly","termid":"GO:0110082"},{"relation_name":"is_a","term_name":"positive regulation of protein localization","termid":"GO:1903829"},{"relation_name":"positively_regulates","term_name":"protein localization to cell division site involved in mitotic actomyosin contractile ring assembly","termid":"GO:1903476"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007049"},{"rel_name":"positively_regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0008150","GO:0007049"],"is_obsolete":false,"name":"positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly","termid":"GO:0110083"}


id: PR:Q9USH1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A mediator of RNA polymerase II transcription subunit 31 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR13186:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator of RNA polymerase II transcription subunit 31 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCP31B10.03c","secondary_identifiers":["UniProtKB:Q9USH1"],"synonyms":[{"name":"SPCP31B10.03c","type":"related"},{"name":"Spom972h-MED31","type":"exact"},{"name":"cell separation protein sep10 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"mediator complex subunit 31 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"sep10","type":"related"},{"name":"soh1 homolog (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9USH1"}


id: PBO:0039150
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"AK3 pseudogene 5","termid":"PBO:0039150"}


id: PBO:0002741
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"signal recognition particle subunit Srp14","termid":"PBO:0002741"}


id: GO:1900622
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Calcium-mediated signaling that results in positive regulation of transcription from an RNA polymerase II promoter.","definition_xrefs":["PMID:9407035","GOC:BHF","GOC:bf","GOC:TermGenie","GOC:dgf","PMID:9407036"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling (obsolete GO:1900622)","synonyms":[{"name":"activation of global transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"related"},{"name":"activation of transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"exact"},{"name":"calcineurin-dependent transcription activation","type":"narrow"},{"name":"calcineurin-dependent transcriptional induction","type":"narrow"},{"name":"calcineurin-mediated activation of transcription","type":"narrow"},{"name":"positive regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"related"},{"name":"positive regulation of global transcription from Pol II promoter by calcium-mediated signaling","type":"related"},{"name":"positive regulation of transcription from Pol II promoter by calcium-mediated signaling","type":"exact"},{"name":"positive regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling","type":"related"},{"name":"stimulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"narrow"},{"name":"stimulation of transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"exact"},{"name":"up regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"related"},{"name":"up regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"exact"},{"name":"up-regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"related"},{"name":"up-regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"exact"},{"name":"upregulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"related"},{"name":"upregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling","type":"exact"}],"termid":"GO:1900622"}


id: GO:0051136
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.","definition_xrefs":["PMID:12154375","ISBN:0781735149","PMID:9133426"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of alpha-beta T cell differentiation","termid":"GO:0046637"},{"relation_name":"regulates","term_name":"NK T cell differentiation","termid":"GO:0001865"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of NK T cell differentiation","synonyms":[{"name":"regulation of NK T cell development","type":"related"},{"name":"regulation of NK T lymphocyte differentiation","type":"exact"},{"name":"regulation of NK T-cell differentiation","type":"exact"},{"name":"regulation of NK T-lymphocyte differentiation","type":"exact"},{"name":"regulation of NKT cell differentiation","type":"exact"},{"name":"regulation of NT cell differentiation","type":"exact"},{"name":"regulation of natural T cell differentiation","type":"exact"},{"name":"regulation of natural killer T cell differentiation","type":"exact"}],"termid":"GO:0051136"}


id: PBO:0075513
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"signal peptidase complex subunit 2 pseudogene 4","termid":"PBO:0075513"}


id: PR:O43045
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An iron-sulfur cluster assembly 2, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","PANTHER:PTHR10072:SF26"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iron-sulfur assembly protein 2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC3B9.17","secondary_identifiers":["UniProtKB:O43045"],"synonyms":[{"name":"SPBC3B9.17","type":"related"},{"name":"Spom972h-ISCA2","type":"exact"}],"termid":"PR:O43045"}


id: PBO:0043537
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"component of oligomeric golgi complex 5","termid":"PBO:0043537"}


id: PBO:0062198
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily U member 1 pseudogene","termid":"PBO:0062198"}


id: GO:0090348
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.","definition_xrefs":["GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of organohalogen metabolic process","termid":"GO:0090347"},{"relation_name":"regulates","term_name":"organofluorine metabolic process","termid":"GO:0090346"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of organofluorine metabolic process","termid":"GO:0090348"}


id: GO:0042315
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids.","definition_xrefs":["GOC:curators"],"gene_count":0,"genotype_count":0,"name":"obsolete cytosol nonspecific dipeptidase activity (obsolete GO:0042315)","synonyms":[{"name":"cytosol nonspecific dipeptidase activity","type":"exact"}],"termid":"GO:0042315"}


id: GO:0010367
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space.","definition_xrefs":["GOC:tair_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isoamylase complex","termid":"GO:0043033"},{"relation_name":"part_of","term_name":"extracellular region","termid":"GO:0005576"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005576"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575","GO:0005576"],"is_obsolete":false,"name":"extracellular isoamylase complex","termid":"GO:0010367"}


id: MONDO:1010292
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ankylosing spondylitis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rheumatoid arthritis, non-human animal","termid":"MONDO:1010294"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankylosing spondylitis, non-human animal","secondary_identifiers":["OMIA:000046"],"termid":"MONDO:1010292","xrefs":{"Monarch":{"xref_id":"1010292"}}}


id: GO:0014909
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.","definition_xrefs":["GOC:mtg_muscle","CL:0000192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscle cell migration","termid":"GO:0014812"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"smooth muscle cell migration","termid":"GO:0014909"}


id: PBO:0087691
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis and is involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP160","termid":"PBO:0087691"}


id: GO:0002939
data:
  {"annotated_genes":["SJAG_00255","SJAG_04993"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[72881,79869],"is_not":false,"summary":null,"term":"GO:0002939"}]},"cv_name":"biological_process","definition":"The process whereby a guanine in tRNA is methylated at position N1 of the guanine.","definition_xrefs":["ISBN:155581073X","ISBN:1555811337"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA methylation","termid":"GO:0030488"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00255":null,"SJAG_04993":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0006399"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006399","GO:0010467","GO:0008150"],"is_obsolete":false,"name":"tRNA N1-guanine methylation","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"tRNA m1-guanine biosynthesis","type":"related"}],"termid":"GO:0002939","terms_by_termid":{"GO:0002939":null}}


id: PBO:0084547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Member of the PUF protein family; PUF family is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors","termid":"PBO:0084547"}


id: GO:0014918
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis.","definition_xrefs":["GOC:mtg_cardio"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of natriuresis by pressure natriuresis (obsolete GO:0014918)","synonyms":[{"name":"positive regulation of natriuresis by pressure natriuresis","type":"exact"}],"termid":"GO:0014918"}


id: PBO:0039787
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"aquarius intron-binding spliceosomal factor","termid":"PBO:0039787"}


id: GO:0021901
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.","definition_xrefs":["GOC:cls","GOC:dgh","GOC:dph","GOC:jid","GO_REF:0000021","PMID:16226447"],"direct_ancestors":[{"relation_name":"is_a","term_name":"commitment of multipotent stem cells to neuronal lineage in forebrain","termid":"GO:0021898"},{"relation_name":"part_of","term_name":"early neuron differentiation in forebrain","termid":"GO:0021862"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"early neuron fate commitment in forebrain","termid":"GO:0021901"}


id: PBO:0088169
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Widely-conserved NADHX dehydratase; converts (S)-NADHX to NADH in ATP-dependent manner; YKL151C promoter contains STREs (stress response elements) and expression is induced by heat shock or methyl methanesulfonate; downstream intergenic region drives antisense expression and mediates coordinated regulation of YKL151C and GPM1 phosphoglycerate mutase; protein abundance increases in response to DNA replication stress; homolog of Carkd in mammals and C-terminus of YjeF in E.coli","termid":"PBO:0088169"}


id: GO:0050096
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH4.","definition_xrefs":["RHEA:12829","EC:4.3.1.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ammonia-lyase activity","termid":"GO:0016841"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003824","GO:0016829","GO:0003674"],"is_obsolete":false,"name":"methylaspartate ammonia-lyase activity","secondary_identifiers":["KEGG_REACTION:R03696","MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN"],"synonyms":[{"name":"3-methylaspartase activity","type":"related"},{"name":"L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)","type":"related"},{"name":"L-threo-3-methylaspartate ammonia-lyase activity","type":"related"},{"name":"beta-methylaspartase activity","type":"related"}],"termid":"GO:0050096"}


id: GO:0047856
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.","definition_xrefs":["RHEA:10360"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016788","GO:0003824","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"dihydrocoumarin hydrolase activity","secondary_identifiers":["MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN","EC:3.1.1.35","KEGG_REACTION:R03692"],"synonyms":[{"name":"3,4-dihydrocoumarin hydrolase activity","type":"exact"},{"name":"dihydrocoumarin lactonohydrolase activity","type":"related"},{"name":"dihydrocoumarin lipase activity","type":"exact"}],"termid":"GO:0047856"}


id: GO:0071722
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.","definition_xrefs":["PMID:20221439","PMID:11313333","GOC:kmv"],"direct_ancestors":[{"relation_name":"is_a","term_name":"detoxification","termid":"GO:0098754"},{"relation_name":"part_of","term_name":"response to arsenic-containing substance","termid":"GO:0046685"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0098754"}],"interesting_parent_ids":["GO:0098754","GO:0008150"],"is_obsolete":false,"name":"detoxification of arsenic-containing substance","synonyms":[{"name":"detoxification of arsenic","type":"exact"}],"termid":"GO:0071722"}


id: PBO:0043182
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CDGSH iron sulfur domain 2","termid":"PBO:0043182"}


id: PBO:0013820
data:
  {"annotation_feature_type":"gene","cv_name":"subunit_composition","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dimeric","termid":"PBO:0013820"}


id: GO:0098025
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached.","definition_xrefs":["GOC:bm","VZ:3957"],"direct_ancestors":[{"relation_name":"is_a","term_name":"virion component","termid":"GO:0044423"},{"relation_name":"part_of","term_name":"virus tail","termid":"GO:0098015"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"virus tail, baseplate","synonyms":[{"name":"bacteriophage baseplate","type":"narrow"},{"name":"tail structure","type":"related"},{"name":"tail tip","type":"related"}],"termid":"GO:0098025"}


id: PBO:0069937
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 1230, pseudogene","termid":"PBO:0069937"}


id: GO:1903001
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.","definition_xrefs":["PMID:24345162","GO_REF:0000058","GOC:sjp","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of lipid transport","termid":"GO:0032369"},{"relation_name":"is_a","term_name":"negative regulation of transport across blood-brain barrier","termid":"GO:0150202"},{"relation_name":"is_a","term_name":"regulation of lipid transport across blood-brain barrier","termid":"GO:1903000"},{"relation_name":"negatively_regulates","term_name":"lipid transport across blood-brain barrier","termid":"GO:1990379"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0006810","GO:0008150"],"is_obsolete":false,"name":"negative regulation of lipid transport across blood-brain barrier","synonyms":[{"name":"down regulation of lipid transport across blood brain barrier","type":"exact"},{"name":"down-regulation of lipid transport across blood brain barrier","type":"exact"},{"name":"downregulation of lipid transport across blood brain barrier","type":"exact"},{"name":"inhibition of lipid transport across blood brain barrier","type":"narrow"},{"name":"negative regulation of lipid transport across blood brain barrier","type":"exact"}],"termid":"GO:1903001"}


id: GO:0004473
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH.","definition_xrefs":["RHEA:18253"],"direct_ancestors":[{"relation_name":"is_a","term_name":"malic enzyme activity","termid":"GO:0004470"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"malate dehydrogenase (decarboxylating) (NADP+) activity","secondary_identifiers":["MetaCyc:MALIC-NADP-RXN","Reactome:R-HSA-9012036","EC:1.1.1.40","KEGG_REACTION:R00216","Reactome:R-HSA-9012349"],"synonyms":[{"name":"'malic' enzyme","type":"related"},{"name":"(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)","type":"related"},{"name":"L-malate:NADP oxidoreductase activity","type":"related"},{"name":"NADP-linked decarboxylating malic enzyme","type":"related"},{"name":"NADP-malic enzyme activity","type":"related"},{"name":"NADP-specific malate dehydrogenase activity","type":"related"},{"name":"NADP-specific malic enzyme","type":"related"},{"name":"malate dehydrogenase (NADP, decarboxylating)","type":"related"},{"name":"malate dehydrogenase (decarboxylating, NADP)","type":"related"}],"termid":"GO:0004473"}


id: GO:0102934
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP.","definition_xrefs":["GOC:pz","RHEA:28230"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016491"],"is_obsolete":false,"name":"costunolide synthase activity","secondary_identifiers":["MetaCyc:RXN-8971","EC:1.14.14.150"],"termid":"GO:0102934"}


id: PBO:0072813
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sterile alpha motif domain containing 9","termid":"PBO:0072813"}


id: PBO:0111909
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repxeat protein","termid":"PBO:0111909"}


id: PBO:0087466
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of a palmitoyltransferase; this complex adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole; palmitoyltransferase is composed of Erf2p and Shr5p","termid":"PBO:0087466"}


id: PBO:0016118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"silenced P-specific polypeptide Pc","termid":"PBO:0016118"}


id: PBO:0067260
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 334, pseudogene","termid":"PBO:0067260"}


id: MONDO:0005126
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A principal or polar form of leprosy in which the skin lesions are few and are sharply demarcated. Peripheral nerve involvement is pronounced and may be severe. Unlike lepromatous leprosy (leprosy, lepromatous), the lepromin test is positive. Tuberculoid leprosy is rarely a source of infection to others.","definition_xrefs":["MESH:D015441"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leprosy","termid":"MONDO:0005124"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tuberculoid leprosy","secondary_identifiers":["EFO:0001056","SCTID:70143003","ICD10CM:A30.1","UMLS:C0023351","DOID:1025","icd11.foundation:310697776","ICD9:030.1","MEDGEN:6050"],"synonyms":[{"name":"smooth leprosy","type":"exact"},{"name":"tuberculoid leprosy [type T]","type":"exact"},{"name":"type T leprosy","type":"exact"}],"termid":"MONDO:0005126","xrefs":{"Monarch":{"xref_id":"0005126"}}}


id: MONDO:0003210
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.","definition_xrefs":["NCIT:C35417"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intrahepatic bile duct cancer","termid":"MONDO:0001487"},{"relation_name":"is_a","term_name":"cholangiocarcinoma","termid":"MONDO:0019087"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"intrahepatic cholangiocarcinoma","secondary_identifiers":["GARD:6042","SCTID:109842005","UMLS:C0345905","DOID:4928","MEDGEN:87521","icd11.foundation:1253728223","ONCOTREE:IHCH","EFO:1001961"],"synonyms":[{"name":"ICC","type":"exact"},{"name":"IHCH","type":"related"},{"name":"cholangiocarcinoma, intrahepatic, malignant","type":"exact"},{"name":"intrahepatic Cholangiocellular carcinoma","type":"exact"},{"name":"intrahepatic bile duct cancer (cholangiocarcinoma)","type":"exact"},{"name":"intrahepatic bile duct carcinoma","type":"exact"},{"name":"intrahepatic carcinoma of bile duct","type":"exact"},{"name":"intrahepatic carcinoma of the bile duct","type":"exact"},{"name":"intrahepatic cholangiocarcinoma","type":"exact"},{"name":"intrahepatic cholangiocarcinoma (bile duct cancer)","type":"exact"},{"name":"peripheral cholangiocarcinoma","type":"exact"}],"termid":"MONDO:0003210","xrefs":{"Monarch":{"xref_id":"0003210"}}}


id: GO:0021937
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that mediates the transfer of information from Purkinje cells to granule cell precursors.","definition_xrefs":["GOC:jid","GOC:dgh","GOC:dph","PMID:15157725","PMID:32554107","GOC:cls","GO_REF:0000021"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell signaling","termid":"GO:0007267"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"cerebellar Purkinje cell-granule cell precursor cell signaling","termid":"GO:0021937"}


id: GO:0005359
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.","definition_xrefs":["GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"D-glucose:proton symporter activity","termid":"GO:0005356"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"low-affinity D-glucose:proton symporter activity","synonyms":[{"name":"low-affinity glucose:proton symporter activity","type":"exact"},{"name":"low-affinity hydrogen/glucose transporter activity","type":"broad"},{"name":"low-affinity hydrogen:glucose symporter activity","type":"exact"},{"name":"low-affinity hydrogen:glucose transporter activity","type":"broad"}],"termid":"GO:0005359"}


id: PBO:0051072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy diversity 5-24 (non-functional)","termid":"PBO:0051072"}


id: SO:0002093
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A variant that impacts the internal interactions of the resulting polypeptide structure.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"3D_polypeptide_structure_variant","termid":"SO:0001599"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"structural_interaction_variant","synonyms":[{"name":"structural interaction variant","type":"exact"}],"termid":"SO:0002093"}


id: PBO:0003689
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA export protein Mep33","termid":"PBO:0003689"}


id: PBO:0084459
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR2 has a paralog, YUR1, that arose from the whole genome duplication","termid":"PBO:0084459"}


id: PBO:0053174
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine, glutamate and lysine rich 1","termid":"PBO:0053174"}


id: MONDO:0100138
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A mitochondrial myopathy caused by defects in the MICOS subunit gene APOO (MIC26). Modelling in yeast and flies demonstrate an inability to insert MICOS complex into the inner mitohondrial membrane. Associated symptoms include, lactic acidosis, cognitive impairment and autistic features.","definition_xrefs":["PMID:32439808"],"direct_ancestors":[{"relation_name":"is_a","term_name":"congenital nervous system disorder","termid":"MONDO:0002320"},{"relation_name":"is_a","term_name":"inborn mitochondrial myopathy","termid":"MONDO:0009637"},{"relation_name":"is_a","term_name":"X-linked recessive disease","termid":"MONDO:0020605"},{"relation_name":"is_a","term_name":"hereditary neuromuscular disease","termid":"MONDO:0100546"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069","MONDO:0005336","MONDO:0002320"],"is_obsolete":false,"name":"X-linked recessive mitochondrial myopathy","synonyms":[{"name":"X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features","type":"exact"}],"termid":"MONDO:0100138","xrefs":{"Monarch":{"xref_id":"0100138"}}}


id: PBO:0040783
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Beta cell long intergenic noncoding RNA 1","termid":"PBO:0040783"}


id: GO:0009350
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia.","definition_xrefs":["PMID:1550360"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intracellular protein-containing complex","termid":"GO:0140535"},{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"ethanolamine ammonia-lyase complex","termid":"GO:0009350"}


id: FYPO:0005083
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at non-coding RNA (ncRNA) genes is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PMID:21151114","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to chromatin during vegetative growth","termid":"FYPO:0001509"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001312","FYPO:0001320","FYPO:0000257","FYPO:0000138"],"is_obsolete":false,"name":"normal protein localization to chromatin at ncRNA gene","synonyms":[{"name":"normal protein localisation to chromatin at ncRNA gene","type":"exact"},{"name":"normal protein localization to chromatin at ncRNA gene during mitotic cell cycle","type":"related"},{"name":"normal protein localization to chromatin at ncRNA gene during vegetative growth","type":"exact"}],"termid":"FYPO:0005083"}


id: GO:0061809
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NAD+ + H2O = ADP-D-ribose + nicotinamide + H+, in a two step reaction: first an ADP-ribosyl cyclase reaction to synthesise cyclic ADP-ribose, followed by a cyclic ADP-ribose hydrolase reaction to generate (linear) ADP-ribose.","definition_xrefs":["EC:3.2.2.6","PMID:11866528"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, hydrolyzing N-glycosyl compounds","termid":"GO:0016799"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016798","GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"NAD+ nucleosidase activity, cyclic ADP-ribose generating","secondary_identifiers":["Reactome:R-HSA-8870346","Reactome:R-HSA-8938076","Reactome:R-HSA-9637699","MetaCyc:NADNUCLEOSID-RXN"],"synonyms":[{"name":"ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase","type":"exact"},{"name":"NAD hydrolase","type":"narrow"},{"name":"NAD(+) nucleosidase","type":"narrow"},{"name":"NADase","type":"narrow"},{"name":"nicotinamide adenine dinucleotide nucleosidase","type":"narrow"}],"termid":"GO:0061809"}


id: PBO:0062024
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 2 subfamily M member 5","termid":"PBO:0062024"}


id: GO:0140161
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in).","definition_xrefs":["PMID:15322102","GOC:ln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic acid:sodium symporter activity","termid":"GO:0005343"},{"relation_name":"is_a","term_name":"secondary active monocarboxylate transmembrane transporter activity","termid":"GO:0015355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"monocarboxylate:sodium symporter activity","termid":"GO:0140161"}


id: GO:1900044
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.","definition_xrefs":["GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein polyubiquitination","termid":"GO:1902914"},{"relation_name":"regulates","term_name":"protein K63-linked ubiquitination","termid":"GO:0070534"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0070647"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0070647","GO:0008150"],"is_obsolete":false,"name":"regulation of protein K63-linked ubiquitination","synonyms":[{"name":"regulation of protein K63-linked polyubiquitination","type":"exact"}],"termid":"GO:1900044"}


id: GO:0004133
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the cleavage of branch points in branched glycogen polymers.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete glycogen debranching enzyme activity (obsolete GO:0004133)","termid":"GO:0004133"}


id: GO:0140537
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification.","definition_xrefs":["PMID:9597751"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molecular function activator activity","termid":"GO:0140677"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0098772"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140677"}],"interesting_parent_ids":["GO:0140677","GO:0098772","GO:0003674"],"is_obsolete":false,"name":"transcription regulator activator activity","termid":"GO:0140537"}


id: MONDO:0018994
data:
  {"annotated_genes":["SJAG_01402","SJAG_03811","SJAG_02016","SJAG_04882"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87062],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010479"},{"annotations":[87294],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010689"},{"annotations":[87999,88000],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010699"}]},"cv_name":"mondo","definition":"A subtype of Charcot-Marie-Tooth disease with genetic defects on the X chromosome.","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary motor and sensory neuropathy","termid":"MONDO:0015358"},{"relation_name":"excluded_subClassOf","term_name":"X-linked syndromic intellectual disability","termid":"MONDO:0020119"},{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"},{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease","termid":"MONDO:0015626"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01402":null,"SJAG_02016":null,"SJAG_03811":null,"SJAG_04882":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease type X","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0050542","ICD9:356.9","MEDGEN:1637021","Orphanet:64747","GARD:12444","SCTID:230552007","UMLS:C4551551"],"synonyms":[{"name":"CMTX","type":"exact"},{"name":"COWCK","type":"exact"},{"name":"X-linked Charcot-Marie-Tooth disease","type":"related"},{"name":"X-linked hereditary motor and sensory neuropathy","type":"exact"}],"termid":"MONDO:0018994","terms_by_termid":{"MONDO:0010479":null,"MONDO:0010689":null,"MONDO:0010699":null},"xrefs":{"Monarch":{"xref_id":"0018994"}}}


id: FYPO:0002113
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell morphology phenotype in which a vegetatively growing cell is inviable, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"has_part","term_name":"curved vegetative cell","termid":"FYPO:0000016"},{"relation_name":"is_a","term_name":"curved vegetative cell","termid":"FYPO:0000016"},{"relation_name":"is_a","term_name":"inviable vegetative cell with abnormal cell morphology","termid":"FYPO:0002273"},{"relation_name":"is_a","term_name":"inviable vegetative cell with abnormal cell shape","termid":"FYPO:0002451"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"has_part","termid":"FYPO:0001320"},{"rel_name":"has_part","termid":"FYPO:0000004"},{"rel_name":"is_a","termid":"FYPO:0000005"},{"rel_name":"has_part","termid":"FYPO:0000005"},{"rel_name":"is_a","termid":"FYPO:0000004"},{"rel_name":"has_part","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000004","FYPO:0001985","FYPO:0000002","FYPO:0000005"],"is_obsolete":false,"name":"inviable curved vegetative cell","synonyms":[{"name":"curved inviable cell","type":"exact"},{"name":"inviable curved cell","type":"exact"},{"name":"inviable curved cell during vegetative growth","type":"exact"},{"name":"inviable curved vegetative cell during mitotic cell cycle","type":"related"},{"name":"lethal; curved vegetative cell","type":"exact"}],"termid":"FYPO:0002113"}


id: FYPO:0004006
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to menadione is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein level during vegetative growth","termid":"FYPO:0000833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000257","FYPO:0000002","FYPO:0001320","FYPO:0001312"],"is_obsolete":false,"name":"normal protein level during cellular response to menadione","synonyms":[{"name":"normal protein accumulation during cellular response to menadione","type":"related"},{"name":"normal protein level during cellular response to menadione during mitotic cell cycle","type":"related"},{"name":"normal protein level during cellular response to menadione during vegetative growth","type":"exact"}],"termid":"FYPO:0004006"}


id: MONDO:0005416
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)","definition_xrefs":["MESH:D020370"],"direct_ancestors":[{"relation_name":"is_a","term_name":"osteoarthritis","termid":"MONDO:0005178"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"osteoarthritis, knee","secondary_identifiers":["EFO:0004616","MEDGEN:98371","UMLS:C0409959"],"termid":"MONDO:0005416","xrefs":{"Monarch":{"xref_id":"0005416"}}}


id: GO:1901242
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out).","definition_xrefs":["GOC:TermGenie","PMID:12057006","PMID:15090538"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic cation transmembrane transporter activity","termid":"GO:0015101"},{"relation_name":"is_a","term_name":"alcohol transmembrane transporter activity","termid":"GO:0015665"},{"relation_name":"is_a","term_name":"ABC-type transporter activity","termid":"GO:0140359"},{"relation_name":"is_a","term_name":"carbohydrate derivative transmembrane transporter activity","termid":"GO:1901505"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"ABC-type doxorubicin transporter activity","secondary_identifiers":["TC:3.A.1.105.1"],"synonyms":[{"name":"ATPase-coupled doxorubicin transmembrane transporter activity","type":"related"},{"name":"doxorubicin transmembrane-transporting ATPase activity","type":"related"}],"termid":"GO:1901242"}


id: PBO:0108578
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome large subunit export factor","termid":"PBO:0108578"}


id: PBO:0113544
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Vacuolar transporter; imports large neutral amino acids into vacuole; targeted to vacuole via AP-3 pathway; member of family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters","termid":"PBO:0113544"}


id: PBO:0110333
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP5PF pseudogene 3","termid":"PBO:0110333"}


id: MONDO:1012409
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"gallbladder mucocele, non-human animal","termid":"MONDO:1011780"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"gallbladder mucocele, dog","secondary_identifiers":["OMIA:001524-9615"],"termid":"MONDO:1012409","xrefs":{"Monarch":{"xref_id":"1012409"}}}


id: GO:1902725
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:23212449"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of skeletal muscle cell differentiation","termid":"GO:2001015"},{"relation_name":"negatively_regulates","term_name":"skeletal muscle satellite cell differentiation","termid":"GO:0014816"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of satellite cell differentiation","synonyms":[{"name":"down regulation of satellite cell differentiation","type":"exact"},{"name":"down-regulation of satellite cell differentiation","type":"exact"},{"name":"downregulation of satellite cell differentiation","type":"exact"},{"name":"inhibition of satellite cell differentiation","type":"narrow"}],"termid":"GO:1902725"}


id: PBO:0002960
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trehalose-phosphate synthase Tps2 (predicted)","termid":"PBO:0002960"}


id: PBO:0088332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial thioredoxin family protein, implicated in sulfur cluster assembly","termid":"PBO:0088332"}


id: GO:0098913
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.","definition_xrefs":["GOC:mtg_cardiac_conduct_nov11","GOC:dph","GOC:tb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane depolarization during cardiac muscle cell action potential","termid":"GO:0086012"},{"relation_name":"part_of","term_name":"ventricular cardiac muscle cell action potential","termid":"GO:0086005"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"membrane depolarization during ventricular cardiac muscle cell action potential","synonyms":[{"name":"electrocardiogram QRS complex","type":"related"},{"name":"ventricular depolarization","type":"related"}],"termid":"GO:0098913"}


id: PBO:0027604
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_protein_localization_to_mitotic_spindle_pole_body_during_metaphase","termid":"PBO:0027604"}


id: GO:0033202
data:
  {"annotated_genes":["SJAG_02822","SJAG_03495","SJAG_04816","SJAG_03898","SJAG_02262","SJAG_03219"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[120183],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0033203"},{"annotations":[96734,72166,97868],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031422"},{"annotations":[111024,112274],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0017117"}]},"cv_name":"cellular_component","definition":"A protein complex that possesses DNA helicase activity.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic complex","termid":"GO:1902494"}],"gene_count":6,"genes_by_uniquename":{"SJAG_02262":null,"SJAG_02822":null,"SJAG_03219":null,"SJAG_03495":null,"SJAG_03898":null,"SJAG_04816":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"DNA helicase complex","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"termid":"GO:0033202","terms_by_termid":{"GO:0017117":null,"GO:0031422":null,"GO:0033203":null}}


id: PBO:0077800
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"torsin family 3 member A","termid":"PBO:0077800"}


id: PBO:0002812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA polymerase I upstream activation factor complex subunit Rrn10","termid":"PBO:0002812"}


id: PBO:0113476
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit VIb of cytochrome c oxidase; cytochrome c oxidase is also known as respiratory Complex IV and is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly and activity of cytochrome c oxidase; phosphorylated; easily released from the intermembrane space, suggesting a loose association with Complex IV","termid":"PBO:0113476"}


id: PATO:0001372
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A physical quality that inheres in propagating wave (light or sound) virtue of the bearer's change in direction when passing from one medium to another.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"radiation reflective quality","termid":"PATO:0001294"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"refractivity","termid":"PATO:0001372"}


id: PBO:0057164
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 320b-2","termid":"PBO:0057164"}


id: PBO:0026727
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_kinetochore_during_mitosis","termid":"PBO:0026727"}


id: MONDO:0030486
data:
  {"annotated_genes":["SJAG_04966","SJAG_01772"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87861,87862],"is_not":false,"summary":null,"term":"MONDO:0030486"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited dystonia","termid":"MONDO:0044807"},{"relation_name":"is_a","term_name":"VPS11-related neurological disorder","termid":"MONDO:0100617"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01772":null,"SJAG_04966":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0003441"}],"interesting_parent_ids":["MONDO:0003441"],"is_obsolete":false,"name":"dystonia 32","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:619637","UMLS:C5562029","MEDGEN:1794239","DOID:0060939"],"synonyms":[{"name":"DYT32","type":"exact"}],"termid":"MONDO:0030486","terms_by_termid":{"MONDO:0030486":null},"xrefs":{"Monarch":{"xref_id":"0030486"}}}


id: PBO:0028139
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_cytosolic_small_ribosomal_subunit_level","termid":"PBO:0028139"}


id: GO:2000657
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.","definition_xrefs":["GOC:BHF"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of apolipoprotein binding (obsolete GO:2000657)","termid":"GO:2000657"}


id: MONDO:0013720
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any classic complement early component deficiency in which the cause of the disease is a mutation in the C4B gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"classic complement early component deficiency","termid":"MONDO:0000015"},{"relation_name":"is_a","term_name":"immunodeficiency due to a classical component pathway complement deficiency","termid":"MONDO:0015699"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"complement component 4b deficiency","secondary_identifiers":["OMIM:614379","MEDGEN:482271","GARD:15797","DOID:0060298","UMLS:C3280641"],"synonyms":[{"name":"C4B classic complement early component deficiency","type":"exact"},{"name":"C4B deficiency","type":"related"},{"name":"C4BD","type":"related"},{"name":"classic complement early component deficiency caused by mutation in C4B","type":"exact"},{"name":"complement component 4B deficiency","type":"related"},{"name":"complement component 4b deficiency","type":"exact"}],"termid":"MONDO:0013720","xrefs":{"Monarch":{"xref_id":"0013720"}}}


id: MONDO:0001754
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A potentially life-threatening pregnancy-related disorder characterized by tonic-clonic seizures in association with hypertension after the twentieth week of gestation and up to six weeks postpartum and in the absence of other potential causes of seizures.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"preeclampsia","termid":"MONDO:0005081"},{"relation_name":"is_a","term_name":"toxemia of pregnancy","termid":"MONDO:0045048"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"eclampsia","secondary_identifiers":["ICD10CM:O15","NCIT:C87167","icd11.foundation:1759760659","DOID:13593","SCTID:303063000","ICD9:642.64","MEDGEN:4443","MESH:D004461","UMLS:C0013537"],"synonyms":[{"name":"eclampsia in puerperium","type":"exact"},{"name":"eclampsia, postpartum","type":"exact"},{"name":"postpartum eclampsia","type":"exact"}],"termid":"MONDO:0001754","xrefs":{"Monarch":{"xref_id":"0001754"}}}


id: PBO:0063230
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protocadherin related 15","termid":"PBO:0063230"}


id: FYPO:0004563
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of alpha-galactosidase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal catalytic activity","termid":"FYPO:0000661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000707","FYPO:0000661","FYPO:0001985","FYPO:0000654"],"is_obsolete":false,"name":"abnormal alpha-galactosidase activity","termid":"FYPO:0004563"}


id: PBO:0066822
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 121","termid":"PBO:0066822"}


id: PBO:0111942
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PMT4 subfamily","termid":"PBO:0111942"}


id: PR:Q9UUB4
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- ade7 gene.","definition_xrefs":["UniProtKB:Q9UUB4","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphoribosylaminoimidazole-succinocarboxamide synthase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC409.10","synonyms":[{"name":"SAICAR synthetase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-ade7","type":"exact"}],"termid":"PR:Q9UUB4"}


id: GO:0036343
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.","definition_xrefs":["GOC:pr","PMID:17159989","Wikipedia:Psychomotor_learning","GOC:nhn"],"direct_ancestors":[{"relation_name":"is_a","term_name":"motor behavior","termid":"GO:0061744"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"psychomotor behavior","termid":"GO:0036343"}


id: GO:2000745
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any positive regulation of transcription from RNA polymerase III promoter that is involved in smooth muscle cell differentiation.","definition_xrefs":["GOC:BHF"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation (obsolete GO:2000745)","synonyms":[{"name":"activation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation","type":"related"},{"name":"activation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation","type":"related"},{"name":"positive regulation of transcription from Pol III promoter of nonstriated muscle cell differentiation","type":"exact"},{"name":"positive regulation of transcription from Pol III promoter of smooth muscle cell differentiation","type":"exact"},{"name":"positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation","type":"exact"},{"name":"positive regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation","type":"exact"},{"name":"positive regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation","type":"exact"},{"name":"stimulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation","type":"related"},{"name":"stimulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation","type":"related"},{"name":"up regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation","type":"exact"},{"name":"up regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation","type":"exact"},{"name":"up-regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation","type":"exact"},{"name":"up-regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation","type":"exact"},{"name":"upregulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation","type":"exact"},{"name":"upregulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation","type":"exact"}],"termid":"GO:2000745"}


id: MONDO:1010360
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Dacryocystitis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of orbital region, non-human animal","termid":"MONDO:1011315"},{"relation_name":"is_a","term_name":"disorder of visual system, non-human animal","termid":"MONDO:1011316"},{"relation_name":"is_a","term_name":"inflammatory disease, non-human animal","termid":"MONDO:1011327"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dacryocystitis, non-human animal","secondary_identifiers":["OMIA:002610"],"termid":"MONDO:1010360","xrefs":{"Monarch":{"xref_id":"1010360"}}}


id: RO:0002015
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.","direct_ancestors":[{"relation_name":"is_a","term_name":"has_regulatory_component_activity","termid":"RO:0002013"},{"relation_name":"is_a","term_name":"positively_regulated_by","termid":"RO:0002336"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"has_positive_regulatory_component_activity","termid":"RO:0002015"}


id: GO:0033723
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.","definition_xrefs":["EC:1.2.1.69"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aldehyde dehydrogenase (NAD+) activity","termid":"GO:0004029"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"fluoroacetaldehyde dehydrogenase (NAD+) activity","secondary_identifiers":["RHEA:16677"],"synonyms":[{"name":"fluoroacetaldehyde:NAD+ oxidoreductase activity","type":"related"}],"termid":"GO:0033723"}


id: MONDO:0014603
data:
  {"annotated_genes":["SJAG_04719"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87097],"is_not":false,"summary":null,"term":"MONDO:0014603"}]},"cv_name":"mondo","definition":"Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the CRYM gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal dominant nonsyndromic hearing loss","termid":"MONDO:0019587"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04719":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0000426"}],"interesting_parent_ids":["MONDO:0019497","MONDO:0000426"],"is_obsolete":false,"name":"autosomal dominant nonsyndromic hearing loss 40","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["DOID:0110566","UMLS:C4084708","GARD:18142","OMIM:616357","MEDGEN:896665"],"synonyms":[{"name":"CRYM autosomal dominant nonsyndromic deafness","type":"narrow"},{"name":"DFNA40","type":"narrow"},{"name":"autosomal dominant deafness 40","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness 40","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness caused by mutation in CRYM","type":"narrow"},{"name":"autosomal dominant nonsyndromic deafness type 40","type":"narrow"},{"name":"autosomal dominant nonsyndromic hearing loss 40","type":"exact"},{"name":"deafness, autosomal dominant 40","type":"narrow"},{"name":"deafness, autosomal dominant type 40","type":"narrow"}],"termid":"MONDO:0014603","terms_by_termid":{"MONDO:0014603":null},"xrefs":{"Monarch":{"xref_id":"0014603"}}}


id: GO:0045591
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.","definition_xrefs":["ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of T cell differentiation","termid":"GO:0045582"},{"relation_name":"is_a","term_name":"regulation of regulatory T cell differentiation","termid":"GO:0045589"},{"relation_name":"positively_regulates","term_name":"regulatory T cell differentiation","termid":"GO:0045066"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0007155"},{"rel_name":"positively_regulates","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0007155","GO:0008150"],"is_obsolete":false,"name":"positive regulation of regulatory T cell differentiation","synonyms":[{"name":"activation of regulatory T cell differentiation","type":"narrow"},{"name":"positive regulation of regulatory T cell development","type":"related"},{"name":"positive regulation of regulatory T lymphocyte differentiation","type":"exact"},{"name":"positive regulation of regulatory T-cell differentiation","type":"exact"},{"name":"positive regulation of regulatory T-lymphocyte differentiation","type":"exact"},{"name":"positive regulation of suppressor T cell differentiation","type":"exact"},{"name":"positive regulation of suppressor T-cell differentiation","type":"exact"},{"name":"stimulation of regulatory T cell differentiation","type":"narrow"},{"name":"up regulation of regulatory T cell differentiation","type":"exact"},{"name":"up-regulation of regulatory T cell differentiation","type":"exact"},{"name":"upregulation of regulatory T cell differentiation","type":"exact"}],"termid":"GO:0045591"}


id: MONDO:0019456
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An acute myeloid leukemia arising de novo and not as a result of treatment. It is characterized by the presence of myelodysplastic features in at least 50% of the cells of at least two hematopoietic cell lines. Patients often present with severe cytopenia.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"bilineal acute myeloid leukemia","termid":"MONDO:0011118"},{"relation_name":"is_a","term_name":"acute myeloid leukemia","termid":"MONDO:0018874"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0004992","MONDO:0005570"],"is_obsolete":false,"name":"acute myeloid leukemia with multilineage dysplasia","secondary_identifiers":["UMLS:C1292773","Orphanet:86845","MEDGEN:224861","icd11.foundation:1235412948","GARD:12761","NCIT:C9289","SCTID:445448008","ICDO:9895/3"],"synonyms":[{"name":"AML with multilineage dysplasia","type":"exact"},{"name":"AML with myelodysplasia-related features","type":"exact"},{"name":"De novo acute myeloid leukaemia with multilineage dysplasia","type":"exact"},{"name":"De novo acute myeloid leukemia with multilineage dysplasia","type":"exact"},{"name":"acute myeloid leukaemia with myelodysplasia-related features","type":"related"},{"name":"acute myeloid leukemia with myelodysplasia-related features","type":"related"}],"termid":"MONDO:0019456","xrefs":{"Monarch":{"xref_id":"0019456"}}}


id: FYPO:0003905
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is normal (i.e. indistinguishable from wild type) during the second meiotic nuclear division.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal subcellular component during vegetative growth","termid":"FYPO:0001313"},{"relation_name":"is_a","term_name":"normal spindle pole body","termid":"FYPO:0005379"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"output_of","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal meiotic spindle pole body morphology during meiosis II","synonyms":[{"name":"normal meiotic SPB morphology during meiosis II","type":"exact"},{"name":"normal meiotic spindle pole body structure during meiosis II","type":"narrow"},{"name":"normal spindle pole body morphology during meiosis II","type":"exact"},{"name":"normal spindle pole body morphology during second meiotic nuclear division","type":"exact"}],"termid":"FYPO:0003905"}


id: PBO:0087297
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Single-stranded DNA endonuclease (with Rad1p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein","termid":"PBO:0087297"}


id: PBO:0073581
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"shisa like 2B","termid":"PBO:0073581"}


id: PBO:0002192
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ShuGOshin","termid":"PBO:0002192"}


id: GO:1901588
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Any microtubule in a dendrite, a neuron projection.","definition_xrefs":["GOC:TermGenie","NIF_Subcellular:sao110773650"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule","termid":"GO:0005874"},{"relation_name":"part_of","term_name":"dendrite","termid":"GO:0030425"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0015630"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575","GO:0015630"],"is_obsolete":false,"name":"dendritic microtubule","synonyms":[{"name":"microtubule of dendrite","type":"exact"},{"name":"microtubulus of dendrite","type":"exact"}],"termid":"GO:1901588"}


id: MONDO:0017698
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"glycogen storage disease due to glycogen branching enzyme deficiency","termid":"MONDO:0009292"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0005066"],"is_obsolete":false,"name":"glycogen storage disease due to glycogen branching enzyme deficiency, congenital neuromuscular form","secondary_identifiers":["UMLS:C1856304","Orphanet:308670","MEDGEN:343523","GARD:17397"],"synonyms":[{"name":"GBE deficiency, congenital neuromuscular form","type":"exact"},{"name":"GSD due to glycogen branching enzyme deficiency, congenital neuromuscular form","type":"exact"},{"name":"GSD type 4, congenital neuromuscular form","type":"exact"},{"name":"GSDIV, congenital neuromuscular form","type":"exact"},{"name":"glycogen storage disease type 4, congenital neuromuscular form","type":"exact"},{"name":"glycogen storage disease type IV, congenital neuromuscular form","type":"exact"},{"name":"glycogenosis due to glycogen branching enzyme deficiency, congenital neuromuscular form","type":"exact"},{"name":"glycogenosis type 4, congenital neuromuscular form","type":"exact"},{"name":"glycogenosis type IV, congenital neuromuscular form","type":"exact"}],"termid":"MONDO:0017698","xrefs":{"Monarch":{"xref_id":"0017698"}}}


id: SO:0000113
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A viral sequence which has integrated into a host genome.","definition_xrefs":["SO:ke"],"direct_ancestors":[{"relation_name":"is_a","term_name":"integrated_mobile_genetic_element","termid":"SO:0001039"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proviral_region","synonyms":[{"name":"proviral region","type":"exact"},{"name":"proviral sequence","type":"related"}],"termid":"SO:0000113"}


id: MONDO:0012420
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive disorder caused by mutations in the MARVELD2 gene, encoding MARVEL domain-containing protein 2. The condition is characterized by profound prelingual deafness.","definition_xrefs":["NCIT:C129024"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hearing loss, autosomal recessive","termid":"MONDO:0019588"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0019497"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0019497"],"is_obsolete":false,"name":"autosomal recessive nonsyndromic hearing loss 49","secondary_identifiers":["MESH:C565717","DOID:0110506","OMIM:610153","MEDGEN:346670","GARD:22619","UMLS:C1857811"],"synonyms":[{"name":"DFNB49","type":"narrow"},{"name":"MARVELD2 autosomal recessive nonsyndromic deafness","type":"narrow"},{"name":"autosomal recessive deafness 49","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness 49","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness caused by mutation in MARVELD2","type":"narrow"},{"name":"autosomal recessive nonsyndromic deafness type 49","type":"narrow"},{"name":"autosomal recessive nonsyndromic hearing loss 49","type":"exact"},{"name":"deafness, autosomal recessive 49","type":"narrow"},{"name":"deafness, autosomal recessive type 49","type":"narrow"}],"termid":"MONDO:0012420","xrefs":{"Monarch":{"xref_id":"0012420"}}}


id: PBO:0077023
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thioesterase superfamily member 5","termid":"PBO:0077023"}


id: PBO:0069041
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 286, pseudogene","termid":"PBO:0069041"}


id: PBO:0070127
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U7 small nuclear 41 pseudogene","termid":"PBO:0070127"}


id: GO:0019621
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"creatinine catabolic process","termid":"GO:0006602"},{"relation_name":"is_a","term_name":"formate metabolic process","termid":"GO:0015942"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0008150"],"is_obsolete":false,"name":"creatinine catabolic process to formate","secondary_identifiers":["MetaCyc:CRNFORCAT-PWY"],"synonyms":[{"name":"creatinine breakdown to formate","type":"exact"},{"name":"creatinine degradation to formate","type":"exact"}],"termid":"GO:0019621"}


id: GO:2000930
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cellobiose metabolic process.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of carbohydrate metabolic process","termid":"GO:0006109"},{"relation_name":"regulates","term_name":"cellobiose metabolic process","termid":"GO:2000891"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"regulation of cellobiose metabolic process","synonyms":[{"name":"regulation of cellobiose metabolism","type":"exact"}],"termid":"GO:2000930"}


id: PR:P25009
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- puc1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P25009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin puc1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC19F5.01c","synonyms":[{"name":"Spom972h-puc1","type":"exact"}],"termid":"PR:P25009"}


id: MONDO:0004903
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"keratitis","termid":"MONDO:0003085"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"deep keratitis","secondary_identifiers":["DOID:9858","ICD9:370.59","MEDGEN:755799","ICD9:370.5","SCTID:445741003","UMLS:C2960633"],"termid":"MONDO:0004903","xrefs":{"Monarch":{"xref_id":"0004903"}}}


id: PBO:0109976
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"autophagy associated heterodimeric guanine nucleotide exchange factor (GEF) subunit Aut12","termid":"PBO:0109976"}


id: GO:0044317
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body.","definition_xrefs":["PMID:26930660"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neuron projection","termid":"GO:0043005"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"rod spherule","synonyms":[{"name":"rod cell spherule","type":"exact"},{"name":"rod photoreceptor spherule","type":"exact"}],"termid":"GO:0044317"}


id: MONDO:0100567
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare hereditary angioedema characterized by potentially life-threatening episodes of subcutaneous and/or submucosal edema without urticaria and with normal levels and function of C1 esterase inhibitor. Patients present with prolonged attacks which last for approximately two to five days and may include nonpitting edema of the skin, severe abdominal symptoms such as pain and swelling, and/or respiratory distress due to upper respiratory airways involvement. Affected locations and frequency of attacks differ slightly between subtypes. Estrogen-containing oral contraceptives and pregnancy are precipitating factors, especially in patients with a factor XII mutation.","definition_xrefs":["Orphanet:528647"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary angioedema","termid":"MONDO:0019623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"hereditary angioedema with normal C1Inh","secondary_identifiers":["MEDGEN:743231","UMLS:C1960459","GARD:22195"],"synonyms":[{"name":"HAE with normal C1 inhibitor","type":"exact"},{"name":"HAE with normal C1Inh","type":"exact"},{"name":"hereditary angioedema with normal C1 inhibitor","type":"exact"},{"name":"hereditary angioneurotic edema with normal C1 inhibitor","type":"exact"},{"name":"hereditary angioneurotic edema with normal C1Inh","type":"exact"}],"termid":"MONDO:0100567","xrefs":{"Monarch":{"xref_id":"0100567"}}}


id: PBO:0054404
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1800","termid":"PBO:0054404"}


id: PATO:0002489
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Overlap with quality inhering in a bearer by virtue of the bearer's being positioned under another entity so as to be covered by some portion of it.","definition_xrefs":["PATOC:WD"],"direct_ancestors":[{"relation_name":"is_a","term_name":"overlap with","termid":"PATO:0001590"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"overlapped by","termid":"PATO:0002489"}


id: GO:0060982
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"artery morphogenesis","termid":"GO:0048844"},{"relation_name":"is_a","term_name":"coronary vasculature morphogenesis","termid":"GO:0060977"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"coronary artery morphogenesis","termid":"GO:0060982"}


id: MONDO:0004225
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A condition characterized by the presence of a monoclonal gammopathy (MG) in which the clonal mass has not reached a predefined state in which the condition is considered malignant. Up to 25% of cases of monoclonal gammopathy of undetermined significance (MGUS) progress to a B-cell malignancy or myeloma. MGUS may occur in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases.","definition_xrefs":["NCIT:C3996"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"plasma cell neoplasm","termid":"MONDO:0004959"},{"relation_name":"is_a","term_name":"monoclonal gammopathy","termid":"MONDO:0004960"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"monoclonal gammopathy of uncertain significance","secondary_identifiers":["SCTID:277577000","ICD9:238.6","ONCOTREE:MGUS","SCTID:58648008","UMLS:C0026470","MESH:D008998","DOID:7442","ICDO:9765/1","MEDGEN:44485"],"synonyms":[{"name":"MGUS","type":"exact"},{"name":"benign monoclonal gammopathy","type":"exact"},{"name":"monoclonal gammopathy Of undetermined significance (MGUS)","type":"exact"},{"name":"monoclonal gammopathy of undetermined significance","type":"exact"},{"name":"monoclonal gammopathy of undetermined significance (MGUS)","type":"exact"},{"name":"monoclonal gammopathy of undetermined significance (morphologic abnormality)","type":"exact"},{"name":"monoclonal gammopathy of unknown significance","type":"exact"},{"name":"monoclonal gammopathy, benign","type":"exact"}],"termid":"MONDO:0004225","xrefs":{"Monarch":{"xref_id":"0004225"}}}


id: PBO:0053309
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lin-37 DREAM MuvB core complex component","termid":"PBO:0053309"}


id: PBO:0085243
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; potential role in the secretory pathway; seamless-GFP and mCherry fusion proteins localize to the vacuole, while SWAT-GFP fusion localizes to both the endoplasmic reticulum and vacuole; suppresses toxicity of slow-folding human Z-type alpha1-antitrypsin variant associated with liver cirrhosis and emphysema","termid":"PBO:0085243"}


id: MONDO:0017322
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with defective bone mineralization (obsolete MONDO:0019705)","termid":"MONDO:0019705"},{"relation_name":"is_a","term_name":"endocrine system disorder","termid":"MONDO:0005151"},{"relation_name":"is_a","term_name":"inborn vitamin metabolic disorder","termid":"MONDO:0005528"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005066"],"is_obsolete":false,"name":"disorders of vitamin D metabolism","secondary_identifiers":["UMLS:C5681017","GARD:21132","MEDGEN:1842308","Orphanet:289098"],"termid":"MONDO:0017322","xrefs":{"Monarch":{"xref_id":"0017322"}}}


id: GO:0031069
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of the hair follicle are generated and organized.","definition_xrefs":["GOC:ln"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure morphogenesis","termid":"GO:0009653"},{"relation_name":"is_a","term_name":"hair cycle process","termid":"GO:0022405"},{"relation_name":"part_of","term_name":"hair follicle development","termid":"GO:0001942"},{"relation_name":"part_of","term_name":"epidermis morphogenesis","termid":"GO:0048730"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hair follicle morphogenesis","termid":"GO:0031069"}


id: GO:1905181
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of urease activity.","definition_xrefs":["PMID:16244137","GO_REF:0000059","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of urease activity (obsolete GO:1905181)","synonyms":[{"name":"regulation of urea amidohydrolase activity","type":"exact"}],"termid":"GO:1905181"}


id: PBO:0029506
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_swollen_spore_population_with_abnormal_spore_shape_(obsolete_FYPO:0002209)","termid":"PBO:0029506"}


id: PBO:0066027
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RAN binding protein 10","termid":"PBO:0066027"}


id: GO:0044408
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism.","definition_xrefs":["GOC:cc"],"gene_count":0,"genotype_count":0,"name":"obsolete growth or development of symbiont on or near host (obsolete GO:0044408)","synonyms":[{"name":"growth or development of organism on or near host surface","type":"exact"},{"name":"growth or development of symbiont on or near host","type":"exact"}],"termid":"GO:0044408"}


id: PBO:0064668
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"peptidylprolyl isomerase A pseudogene 3","termid":"PBO:0064668"}


id: PBO:0016933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific protein Mug68","termid":"PBO:0016933"}


id: MONDO:0021257
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete glomus jugulare neoplasm (obsolete MONDO:0021257)","termid":"MONDO:0021257","xrefs":{"Monarch":{"xref_id":"0021257"}}}


id: PBO:0034342
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-distributary_of","termid":"PBO:0034342"}


id: PBO:0077013
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombospondin 2","termid":"PBO:0077013"}


id: PBO:0004890
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA specific adenosine deaminase (predicted)","termid":"PBO:0004890"}


id: MONDO:0014735
data:
  {"annotated_genes":["SJAG_03345"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87763],"is_not":false,"summary":null,"term":"MONDO:0014735"}]},"cv_name":"mondo","definition":"Any Charcot-Marie-Tooth disease type 2 in which the cause of the disease is a mutation in the VCP gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Charcot-Marie-Tooth disease type 2","termid":"MONDO:0018993"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03345":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0005244"],"is_obsolete":false,"name":"Charcot-Marie-Tooth disease type 2Y","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:17714","NCIT:C168974","MEDGEN:1800449","Orphanet:435387","DOID:0110168","UMLS:C5569026","OMIM:616687"],"synonyms":[{"name":"CMT2 due to VCP mutation","type":"exact"},{"name":"CMT2Y","type":"exact"},{"name":"Charcot-Marie-Tooth disease type 2 caused by mutation in VCP","type":"exact"},{"name":"Charcot-Marie-Tooth disease, axonal, autosomal dominant, type 2Y","type":"related"},{"name":"Charcot-Marie-Tooth disease, axonal, type 2Y","type":"related"},{"name":"Charcot-Marie-Tooth disease, axonal, type 2y","type":"exact"},{"name":"Charcot-Marie-Tooth disease, type 2Y","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy type 2Y","type":"exact"},{"name":"Charcot-Marie-Tooth neuropathy, type 2Y","type":"related"},{"name":"VCP Charcot-Marie-Tooth disease type 2","type":"exact"},{"name":"autosomal dominant Charcot-Marie-Tooth disease type 2 due to VCP mutation","type":"exact"},{"name":"autosomal dominant Charcot-Marie-Tooth disease type 2Y","type":"related"},{"name":"autosomal dominant axonal Charcot-Marie-Tooth type 2Y","type":"exact"}],"termid":"MONDO:0014735","terms_by_termid":{"MONDO:0014735":null},"xrefs":{"Monarch":{"xref_id":"0014735"}}}


id: PBO:0034204
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-in_heterochronous_homology_relationship_with","termid":"PBO:0034204"}


id: MONDO:0006313
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign, mucus-filled cervical cyst that occurs when mucus-secreting columnar epithelial cells are covered with squamous epithelium.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uterine cervix neoplasm","termid":"MONDO:0021230"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nabothian cyst","secondary_identifiers":["NCIT:C34835","Wikipedia:Nabothian_cyst","icd11.foundation:1329172977","EFO:1000390","UMLS:C0027269","SCTID:24565001","MEDGEN:6510"],"termid":"MONDO:0006313","xrefs":{"Monarch":{"xref_id":"0006313"}}}


id: PATO:0001167
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A structural quality inhering in a bearer by virtue of the bearer being harmed or injured or spoiled, such that its functionality is impaired.","definition_xrefs":["WordNet:WordNet"],"direct_ancestors":[{"relation_name":"is_a","term_name":"damage","termid":"PATO:0001020"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"damaged","termid":"PATO:0001167"}


id: MONDO:0850073
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"craniosynostosis","termid":"MONDO:0015469"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"non-syndromic unicoronal craniosynostosis","secondary_identifiers":["Orphanet:620102","MEDGEN:1842408","GARD:22470","UMLS:C5680401"],"termid":"MONDO:0850073","xrefs":{"Monarch":{"xref_id":"0850073"}}}


id: MONDO:1012259
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"spinal dysraphism, non-human animal","termid":"MONDO:1011671"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spinal dysraphism, dog","secondary_identifiers":["OMIA:000938-9615"],"termid":"MONDO:1012259","xrefs":{"Monarch":{"xref_id":"1012259"}}}


id: PBO:0032703
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_level_of_histone_H3_in_cell","termid":"PBO:0032703"}


id: PBO:0027245
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_polyadenylated_5.8S_rRNA_level","termid":"PBO:0027245"}


id: PBO:0064861
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein phosphatase 1 regulatory subunit 16B","termid":"PBO:0064861"}


id: GO:0006969
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:add"],"gene_count":0,"genotype_count":0,"name":"obsolete melanotic tumor response (obsolete GO:0006969)","synonyms":[{"name":"melanotic mass response","type":"exact"},{"name":"melanotic tumor response","type":"exact"}],"termid":"GO:0006969"}


id: PBO:0029538
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_mixed_population_including_spores,_germinated_spores_and_tapered_cells_(obsolete_FYPO:0002184)","termid":"PBO:0029538"}


id: GO:0002419
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.","definition_xrefs":["PMID:16730260","GOC:add","ISBN:0781735149"],"direct_ancestors":[{"relation_name":"is_a","term_name":"T cell mediated cytotoxicity","termid":"GO:0001913"},{"relation_name":"is_a","term_name":"T cell mediated immune response to tumor cell","termid":"GO:0002424"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"T cell mediated cytotoxicity directed against tumor cell target","synonyms":[{"name":"T lymphocyte mediated cytotoxicity directed against tumor cell target","type":"exact"},{"name":"T-cell mediated cytotoxicity directed against tumor cell target","type":"exact"},{"name":"T-lymphocyte mediated cytotoxicity directed against tumor cell target","type":"exact"}],"termid":"GO:0002419"}


id: PBO:0005057
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"wtf element Wtf5","termid":"PBO:0005057"}


id: PBO:0042964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coiled-coil-helix-coiled-coil-helix domain containing 4 pseudogene 2","termid":"PBO:0042964"}


id: FYECO:0000073
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in minimal medium where DHA (dihydroxyacetone) is the main carbon source.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping defined medium","termid":"FYECO:0000013"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DHA minimal medium","synonyms":[{"name":"DHA MM","type":"exact"},{"name":"dihydroxyacetone MM","type":"exact"},{"name":"dihydroxyactone minimal medium","type":"exact"}],"termid":"FYECO:0000073"}


id: PR:O42872
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An exosome complex component RRP41 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO01323","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exosome complex component ski6 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC3G9.10c","secondary_identifiers":["UniProtKB:O42872"],"synonyms":[{"name":"Spom972h-EXOSC4","type":"exact"},{"name":"ribosomal RNA-processing protein 41 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O42872"}


id: PBO:0038427
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha-2-macroglobulin pseudogene 1","termid":"PBO:0038427"}


id: FYECO:0000266
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Experiments were performed in medium containing glucose (typically <2% w/v), salts, water and with xanthine as the nitrogen source.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"grouping defined medium","termid":"FYECO:0000013"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glucose MM, xanthine nitrogen source","termid":"FYECO:0000266"}


id: FYPO:0008300
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed during prophase of the first division of the meiotic cell cycle in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized.","definition_xrefs":["PomBase:pc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal protein localization during meiosis","termid":"FYPO:0003549"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001985","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"abnormal punctate nuclear protein localization during meiotic prophase I","termid":"FYPO:0008300"}


id: GO:0120184
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components.","definition_xrefs":["PMID:25490267"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of focal adhesion disassembly","termid":"GO:0120182"},{"relation_name":"is_a","term_name":"negative regulation of cell-substrate junction organization","termid":"GO:0150118"},{"relation_name":"negatively_regulates","term_name":"focal adhesion disassembly","termid":"GO:0120181"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of focal adhesion disassembly","termid":"GO:0120184"}


id: PR:Q9UT45
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- eng1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UT45"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endo-1,3(4)-beta-glucanase 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC821.09","synonyms":[{"name":"Spom972h-eng1","type":"exact"},{"name":"endo-1,3-beta-glucanase 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"endo-1,4-beta-glucanase 1 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"laminarinase-1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UT45"}


id: GO:0099577
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"presynaptic modulation of chemical synaptic transmission","termid":"GO:0099171"},{"relation_name":"is_a","term_name":"regulation of translation at synapse, modulating synaptic transmission","termid":"GO:0099547"},{"relation_name":"is_a","term_name":"regulation of translation at presynapse","termid":"GO:0140244"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0010467","GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of translation at presynapse, modulating synaptic transmission","termid":"GO:0099577"}


id: PBO:0039028
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ArfGAP with GTPase domain, ankyrin repeat and PH domain 4","termid":"PBO:0039028"}


id: GO:0106362
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H+ + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP.","definition_xrefs":["PMID:23955153","GOC:sp","RHEA:66632","PMID:30619781"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein N-acetylglucosaminyltransferase activity","termid":"GO:0016262"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"}],"interesting_parent_ids":["GO:0003674","GO:0140096","GO:0003824","GO:0016740","GO:0016757"],"is_obsolete":false,"name":"protein-arginine N-acetylglucosaminyltransferase activity","termid":"GO:0106362"}


id: GO:0110162
data:
  {"annotated_genes":["SJAG_00244"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[117032],"is_not":false,"summary":null,"term":"GO:0110162"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).","definition_xrefs":["GOC:vw","PMID:27697865"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of mitotic spindle elongation","termid":"GO:0032888"},{"relation_name":"is_a","term_name":"regulation of mitotic spindle organization","termid":"GO:0060236"},{"relation_name":"regulates","term_name":"mitotic spindle elongation (spindle phase three)","termid":"GO:0061805"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00244":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0000226"},{"rel_name":"regulates","termid":"GO:0007010"},{"rel_name":"regulates","termid":"GO:0007049"}],"interesting_parent_ids":["GO:0007010","GO:0008150","GO:0000226","GO:0007049"],"is_obsolete":false,"name":"regulation of mitotic spindle elongation (spindle phase three)","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0110162","terms_by_termid":{"GO:0110162":null}}


id: GO:0097560
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.","definition_xrefs":["GOC:giardia","ISBN:9780124260207","PMID:5961344","PMID:16607022"],"direct_ancestors":[{"relation_name":"is_a","term_name":"9+2 motile cilium","termid":"GO:0097729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"left caudal flagellum","synonyms":[{"name":"left caudal cilium","type":"exact"}],"termid":"GO:0097560"}


id: GO:0005522
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.","definition_xrefs":["ISBN:0721662544"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein binding","termid":"GO:0005515"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"profilin binding","termid":"GO:0005522"}


id: PBO:0001054
data:
  {"annotation_feature_type":"gene","cv_name":"cat_act","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bifunctional enzyme","termid":"PBO:0001054"}


id: MONDO:0000109
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete basal ganglia calcification, idiopathic (obsolete MONDO:0000109)","termid":"MONDO:0000109","xrefs":{"Monarch":{"xref_id":"0000109"}}}


id: GO:0005117
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to wishful thinking (Wit), a type II bone morphogenic protein receptor.","definition_xrefs":["PMID:11856529","GOC:ceb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"signaling receptor binding","termid":"GO:0005102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0005515","GO:0003674"],"is_obsolete":false,"name":"wishful thinking binding","synonyms":[{"name":"SE20 receptor binding","type":"narrow"},{"name":"Wit binding","type":"exact"},{"name":"Wit ligand","type":"narrow"},{"name":"wishful thinking ligand","type":"narrow"}],"termid":"GO:0005117"}


id: MONDO:0700242
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any retinopathy caused by a heterozygous variant in the IMPG2 gene.","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited retinal dystrophy","termid":"MONDO:0019118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"IMPG2-related dominant retinopathy","synonyms":[{"name":"IMPG2-related dominant retinopathy","type":"exact"}],"termid":"MONDO:0700242","xrefs":{"Monarch":{"xref_id":"0700242"}}}


id: PBO:0004422
data:
  {"annotation_feature_type":"gene","cv_name":"gene_ex","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcriptionally regulates eng1 target genes","termid":"PBO:0004422"}


id: GO:0052048
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete interaction with host via secreted substance (obsolete GO:0052048)","synonyms":[{"name":"interaction with host via secreted substance during symbiotic interaction","type":"related"},{"name":"interaction with host via secreted substance involved in symbiotic interaction","type":"related"}],"termid":"GO:0052048"}


id: PBO:0064204
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PLAG1 zinc finger","termid":"PBO:0064204"}


id: GO:0016344
data:
  {"annotated_genes":["SJAG_02814","SJAG_00794","SJAG_01805","SJAG_03540","SJAG_02761","SJAG_01613","SJAG_02624","SJAG_04076","SJAG_03683"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[111088,104334,101099,66687,95641,102268,97175,117907,70160],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1990571"}]},"cv_name":"biological_process","definition":"The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome movement towards spindle pole","termid":"GO:0051305"},{"relation_name":"is_a","term_name":"meiotic cell cycle process","termid":"GO:1903046"},{"relation_name":"part_of","term_name":"meiotic chromosome segregation","termid":"GO:0045132"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00794":null,"SJAG_01613":null,"SJAG_01805":null,"SJAG_02624":null,"SJAG_02761":null,"SJAG_02814":null,"SJAG_03540":null,"SJAG_03683":null,"SJAG_04076":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0007049"},{"rel_name":"part_of","termid":"GO:0140013"}],"interesting_parent_ids":["GO:0051179","GO:0008150","GO:0140013","GO:0007049"],"is_obsolete":false,"name":"meiotic chromosome movement towards spindle pole","references_by_uniquename":{"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"chromosome migration to spindle pole during meiosis","type":"exact"},{"name":"chromosome movement towards spindle pole during meiosis","type":"exact"},{"name":"meiotic chromosome movement","type":"broad"},{"name":"meiotic chromosome movement to spindle pole","type":"exact"}],"termid":"GO:0016344","terms_by_termid":{"GO:1990571":null}}


id: PBO:0091538
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"not functionally complemented by human TPM1 skeletal muscle isoform","termid":"PBO:0091538"}


id: MONDO:0010596
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"primary membranoproliferative glomerulonephritis","termid":"MONDO:0018904"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"membranoproliferative glomerulonephritis, X-linked","secondary_identifiers":["OMIM:305800","MEDGEN:336706","MESH:C564423","UMLS:C1844501"],"synonyms":[{"name":"Mesangiocapillary glomerulonephritis, X-linked","type":"related"},{"name":"membranoproliferative glomerulonephritis, X-linked","type":"exact"}],"termid":"MONDO:0010596","xrefs":{"Monarch":{"xref_id":"0010596"}}}


id: GO:0052633
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: cis-aconitate + H2O = isocitrate.","definition_xrefs":["MetaCyc:ACONITATEHYDR-RXN","GOC:pde","GOC:vw","EC:4.2.1.3"],"gene_count":0,"genotype_count":0,"name":"obsolete isocitrate hydro-lyase (cis-aconitate-forming) activity (obsolete GO:0052633)","synonyms":[{"name":"aconitate hydratase activity","type":"broad"},{"name":"cis-aconitase activity","type":"broad"},{"name":"citrate hydro-lyase activity","type":"broad"},{"name":"citrate(isocitrate) hydro-lyase (cis-aconitate-forming)","type":"broad"},{"name":"citrate(isocitrate) hydro-lyase activity","type":"broad"}],"termid":"GO:0052633"}


id: GO:0060081
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of membrane potential","termid":"GO:0042391"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"membrane hyperpolarization","termid":"GO:0060081"}


id: PBO:0042988
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CHEK2 pseudogene 1","termid":"PBO:0042988"}


id: PBO:0043387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CLYBL antisense RNA 1","termid":"PBO:0043387"}


id: PBO:0000631
data:
  {"annotation_feature_type":"gene","cv_name":"genome_org","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"co-transcribed with divergently orientated functionally related gene","termid":"PBO:0000631"}


id: PBO:0062610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 10 subfamily T member 1 pseudogene","termid":"PBO:0062610"}


id: PBO:0076361
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SZRD1 pseudogene 1","termid":"PBO:0076361"}


id: MONDO:0011262
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare multiple congenital anomalies syndrome characterized by the association of camptodactyly, multiple eye defects (fibrosis of the medial rectus muscle, severe myopia, ptosis and exophthalmos), scoliosis, flexion contractures and facial anomalies (arched eyebrows, facial asymmetry with an abnormal skull shape, a prominent nose, small mouth, low-set and dysplastic ears, and a low nuchal hairline).","definition_xrefs":["Orphanet:1323"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome without intellectual disability","termid":"MONDO:0015161"},{"relation_name":"is_a","term_name":"dysostosis","termid":"MONDO:0018234"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005497"}],"interesting_parent_ids":["MONDO:0005497"],"is_obsolete":false,"name":"camptodactyly, myopia, and fibrosis of the medial rectus muscle of eye","secondary_identifiers":["OMIM:602612","UMLS:C1865133","MESH:C535876","GARD:216","MEDGEN:355918","SCTID:715986009"],"synonyms":[{"name":"Rozin hertz Goodman syndrome","type":"related"},{"name":"camptodactyly, joint contractures, facial skeletal defects","type":"related"},{"name":"camptodactyly, myopia, and fibrosis of the medial rectus muscle of eye","type":"exact"}],"termid":"MONDO:0011262","xrefs":{"Monarch":{"xref_id":"0011262"}}}


id: FYPO:0000666
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of a peptidase activity is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal catalytic activity","termid":"FYPO:0000661"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000661"}],"interesting_parent_ids":["FYPO:0000707","FYPO:0000654","FYPO:0000661","FYPO:0001985","FYPO:0000652"],"is_obsolete":false,"name":"abnormal peptidase activity","synonyms":[{"name":"abnormal protease activity","type":"exact"}],"termid":"FYPO:0000666"}


id: FYPO:0000171
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transport phenotype observed in the vegetative growth phase of the life cycle in which late endosome to vacuole transport is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vesicle-mediated transport during vegetative growth","termid":"FYPO:0000213"},{"relation_name":"is_a","term_name":"abnormal vacuolar transport during vegetative growth","termid":"FYPO:0000597"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0000138"],"is_obsolete":false,"name":"abnormal late endosome to vacuole transport","synonyms":[{"name":"abnormal late endosome to vacuole protein transport","type":"narrow"},{"name":"abnormal late endosome to vacuole transport during mitotic cell cycle","type":"related"},{"name":"abnormal late endosome to vacuole transport during vegetative growth","type":"exact"}],"termid":"FYPO:0000171"}


id: PBO:0028799
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_replication_fork_arrest","termid":"PBO:0028799"}


id: PBO:0003688
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.7.7.4","termid":"PBO:0003688"}


id: MONDO:0001802
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"},{"relation_name":"is_a","term_name":"tympanitis","termid":"MONDO:0024616"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"acute tympanitis","secondary_identifiers":["MEDGEN:509976","SCTID:297009","DOID:13790","UMLS:C0155460","ICD9:384.00"],"synonyms":[{"name":"acute myringitis","type":"exact"}],"termid":"MONDO:0001802","xrefs":{"Monarch":{"xref_id":"0001802"}}}


id: PBO:0072710
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RWDD3 divergent transcript","termid":"PBO:0072710"}


id: MONDO:0033310
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"Joubert syndrome","termid":"MONDO:0018772"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Joubert syndrome 31","secondary_identifiers":["GARD:16251","MEDGEN:1618082","OMIM:617761","DOID:0080277","UMLS:C4540355"],"synonyms":[{"name":"JBTS31","type":"related"},{"name":"Joubert syndrome 31","type":"exact"}],"termid":"MONDO:0033310","xrefs":{"Monarch":{"xref_id":"0033310"}}}


id: PBO:0088206
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Zn(II)2Cys6 family transcription factor; positively regulates sterol uptake genes under anaerobic conditions; involved in hypoxic gene expression; represses filamentation-inducing genes during vegetative growth; positively regulates mating with SUT2 by repressing expression of genes that act as mating inhibitors; repressed by STE12; relocalizes from the nucleus to the cytoplasm upon DNA replication stress; SUT1 has a paralog, SUT2, that arose from the whole genome duplication","termid":"PBO:0088206"}


id: MONDO:0017007
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"partial deletion of chromosome X","termid":"MONDO:0017003"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"partial deletion of the long arm of chromosome X","secondary_identifiers":["Orphanet:263756","GARD:20915","MEDGEN:1826028","UMLS:C5679688"],"synonyms":[{"name":"partial deletion of chromosome Xq","type":"exact"},{"name":"partial deletion of the long arm of chromosome type X","type":"exact"},{"name":"partial monosomy of chromosome Xq","type":"exact"},{"name":"partial monosomy of the long arm of chromosome X","type":"exact"}],"termid":"MONDO:0017007","xrefs":{"Monarch":{"xref_id":"0017007"}}}


id: FYPO:0002675
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTDP measured in a cell is higher than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased level of substance in cell during vegetative growth","termid":"FYPO:0001330"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"increased cellular dTDP level","synonyms":[{"name":"increased cellular dTDP level during mitotic cell cycle","type":"related"},{"name":"increased cellular dTDP level during vegetative growth","type":"exact"},{"name":"increased dTDP accumulation","type":"related"}],"termid":"FYPO:0002675"}


id: PBO:0040307
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATPase H+/K+ transporting subunit beta","termid":"PBO:0040307"}


id: MONDO:0009970
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of renal tubular dysgenesis that is caused by a modification of the individual's genome.","definition_xrefs":["MONDO:patterns/genetic"],"direct_ancestors":[{"relation_name":"is_a","term_name":"renal tubular dysgenesis","termid":"MONDO:0017609"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"},{"relation_name":"is_a","term_name":"inherited kidney disorder","termid":"MONDO:0100191"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0005240"],"is_obsolete":false,"name":"renal tubular dysgenesis of genetic origin","secondary_identifiers":["icd11.foundation:616055520","MEDGEN:1826125","OMIM:267430","Orphanet:97369","GARD:16854","UMLS:C5681536"],"synonyms":[{"name":"RTD","type":"related"},{"name":"genetic renal tubular dysgenesis","type":"exact"},{"name":"primitive renal tubule syndrome","type":"related"},{"name":"renal tubular dysgenesis","type":"related"},{"name":"renal tubular dysgenesis of genetic origin","type":"exact"},{"name":"renal tubular dysgenesis with choanal atresia and athelia","type":"related"}],"termid":"MONDO:0009970","xrefs":{"Monarch":{"xref_id":"0009970"}}}


id: PBO:0084209
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Homeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress","termid":"PBO:0084209"}


id: GO:0019817
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.","definition_xrefs":["GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vesicle fusion","termid":"GO:0006906"},{"relation_name":"is_a","term_name":"peroxisome organization","termid":"GO:0007031"},{"relation_name":"part_of","term_name":"peroxisome organization","termid":"GO:0007031"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0061024"},{"rel_name":"is_a","termid":"GO:0007031"},{"rel_name":"part_of","termid":"GO:0006810"},{"rel_name":"part_of","termid":"GO:0007031"},{"rel_name":"part_of","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0061024","GO:0016192","GO:0006810","GO:0008150","GO:0007031"],"is_obsolete":false,"name":"vesicle fusion with peroxisome","termid":"GO:0019817"}


id: PBO:0003375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA snR3","termid":"PBO:0003375"}


id: GO:0044042
data:
  {"annotated_genes":["SJAG_01888","SJAG_01783","SJAG_00963","SJAG_04666","SJAG_00610","SJAG_04659","SJAG_01290","SJAG_04462","SJAG_01171","SJAG_02192","SJAG_05001","SJAG_01561","SJAG_02446","SJAG_02278","SJAG_03587","SJAG_03705","SJAG_03057","SJAG_04483","SJAG_02076","SJAG_04771","SJAG_04184","SJAG_01835","SJAG_01453","SJAG_02178","SJAG_06309","SJAG_03851","SJAG_04073","SJAG_04327","SJAG_05285","SJAG_01288","SJAG_01376","SJAG_00115","SJAG_02222","SJAG_00876","SJAG_00218","SJAG_04236","SJAG_01089","SJAG_01787","SJAG_03646","SJAG_01255","SJAG_01028","SJAG_03123","SJAG_02590","SJAG_04963","SJAG_04668","SJAG_00424","SJAG_04509","SJAG_02916"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[64249,76943,78574],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0006078"},{"annotations":[96312],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034413"},{"annotations":[74753],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034412"},{"annotations":[72369,80559,75281,75109,73158],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070600"},{"annotations":[117802,76275,93434,74756,108030,72799,77629,115133],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0071970"},{"annotations":[79999,104540],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070880"},{"annotations":[103839,96963,103840,110006],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070879"},{"annotations":[72224,72327,76862,75019,78832],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009251"},{"annotations":[105204],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005980"},{"annotations":[81971,74308],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005977"},{"annotations":[73575,75151,80639,73837,81658,74859],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061723"},{"annotations":[78867,80809],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:0045719"},{"annotations":[94261,89321],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:0140748"},{"annotations":[89704],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0032951"},{"annotations":[92597,94245,107264,69386,119901,120034,107839],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0090334"},{"annotations":[96799,94267,104749,91262],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0070610"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide metabolic process","termid":"GO:0005976"}],"gene_count":48,"genes_by_uniquename":{"SJAG_00115":null,"SJAG_00218":null,"SJAG_00424":null,"SJAG_00610":null,"SJAG_00876":null,"SJAG_00963":null,"SJAG_01028":null,"SJAG_01089":null,"SJAG_01171":null,"SJAG_01255":null,"SJAG_01288":null,"SJAG_01290":null,"SJAG_01376":null,"SJAG_01453":null,"SJAG_01561":null,"SJAG_01783":null,"SJAG_01787":null,"SJAG_01835":null,"SJAG_01888":null,"SJAG_02076":null,"SJAG_02178":null,"SJAG_02192":null,"SJAG_02222":null,"SJAG_02278":null,"SJAG_02446":null,"SJAG_02590":null,"SJAG_02916":null,"SJAG_03057":null,"SJAG_03123":null,"SJAG_03587":null,"SJAG_03646":null,"SJAG_03705":null,"SJAG_03851":null,"SJAG_04073":null,"SJAG_04184":null,"SJAG_04236":null,"SJAG_04327":null,"SJAG_04462":null,"SJAG_04483":null,"SJAG_04509":null,"SJAG_04659":null,"SJAG_04666":null,"SJAG_04668":null,"SJAG_04771":null,"SJAG_04963":null,"SJAG_05001":null,"SJAG_05285":null,"SJAG_06309":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"glucan metabolic process","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"glucan metabolism","type":"exact"}],"termid":"GO:0044042","terms_by_termid":{"GO:0005977":null,"GO:0005980":null,"GO:0006078":null,"GO:0009251":null,"GO:0032951":null,"GO:0034412":null,"GO:0034413":null,"GO:0045719":null,"GO:0061723":null,"GO:0070600":null,"GO:0070610":null,"GO:0070879":null,"GO:0070880":null,"GO:0071970":null,"GO:0090334":null,"GO:0140748":null}}


id: MONDO:0014230
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any chronic mucocutaneous candidiasis in which the cause of the disease is a mutation in the TRAF3IP2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"chronic mucocutaneous candidiasis","termid":"MONDO:0015279"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"},{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005046","MONDO:0005093"],"is_obsolete":false,"name":"candidiasis, familial, 8","secondary_identifiers":["GARD:15981","UMLS:C3714992","MEDGEN:811541","OMIM:615527"],"synonyms":[{"name":"CANDF8","type":"related"},{"name":"TRAF3IP2 chronic mucocutaneous candidiasis (disease)","type":"exact"},{"name":"candidiasis, familial chronic mucocutaneous, autosomal recessive","type":"related"},{"name":"candidiasis, familial, 8","type":"exact"},{"name":"candidiasis, familial, type 8","type":"exact"},{"name":"chronic mucocutaneous candidiasis (disease) caused by mutation in TRAF3IP2","type":"exact"}],"termid":"MONDO:0014230","xrefs":{"Monarch":{"xref_id":"0014230"}}}


id: PBO:0070547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7a pseudogene 13","termid":"PBO:0070547"}


id: PBO:0031335
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_bleomycin","termid":"PBO:0031335"}


id: MONDO:0012876
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited thrombophilia","termid":"MONDO:0100240"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"heparin cofactor 2 deficiency","secondary_identifiers":["MESH:C562865","DOID:0111901","UMLS:C0398626","OMIM:612356","MEDGEN:96017","ICD9:286.3","SCTID:234468009"],"synonyms":[{"name":"Hcf 2 deficiency","type":"related"},{"name":"Hcf2 deficiency","type":"related"},{"name":"heparin cofactor 2 deficiency","type":"exact"},{"name":"heparin cofactor II deficiency","type":"related"},{"name":"thrombophilia 10 due to heparin cofactor II deficiency","type":"exact"},{"name":"thrombophilia due to heparin cofactor 2 deficiency","type":"related"}],"termid":"MONDO:0012876","xrefs":{"Monarch":{"xref_id":"0012876"}}}


id: PBO:0039872
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARHGAP29 antisense RNA 1","termid":"PBO:0039872"}


id: PBO:0114107
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"membrane DUF2015 family conserved fungal protein","termid":"PBO:0114107"}


id: MONDO:0008387
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Ring dermoid of cornea is characterized by annular limbal dermoids (growths with a skin-like structure) with corneal and conjunctival extension. Less than 30 cases have been described. Transmission is autosomal dominant and mutations in the PITX2 gene have been suggested as a potential cause of the condition.","definition_xrefs":["Orphanet:91481"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"eye neoplasm","termid":"MONDO:0021220"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"ring dermoid of cornea","secondary_identifiers":["GARD:9696","DOID:0111548","MESH:C535684","OMIM:180550","icd11.foundation:271430543","SCTID:723499000","MEDGEN:357922","UMLS:C1867155"],"synonyms":[{"name":"RDC","type":"related"},{"name":"RING dermoid of cornea","type":"related"},{"name":"Ring dermoid syndrome","type":"exact"},{"name":"bilateral, annular limbal dermoids with corneal and conjunctival extension","type":"related"},{"name":"ring dermoid of cornea","type":"exact"}],"termid":"MONDO:0008387","xrefs":{"Monarch":{"xref_id":"0008387"}}}


id: GO:0043456
data:
  {"annotated_genes":["SJAG_05314","SJAG_00685"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[77908],"is_not":false,"summary":null,"term":"GO:0043456"},{"annotations":[91516],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905857"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of amide metabolic process","termid":"GO:0034248"},{"relation_name":"is_a","term_name":"regulation of generation of precursor metabolites and energy","termid":"GO:0043467"},{"relation_name":"is_a","term_name":"regulation of carbohydrate catabolic process","termid":"GO:0043470"},{"relation_name":"is_a","term_name":"regulation of NADP metabolic process","termid":"GO:1902031"},{"relation_name":"regulates","term_name":"pentose-phosphate shunt","termid":"GO:0006098"}],"gene_count":2,"genes_by_uniquename":{"SJAG_00685":null,"SJAG_05314":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0005975"},{"rel_name":"regulates","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0006091","GO:0008150","GO:0055086","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"regulation of pentose-phosphate shunt","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"regulation of pentose phosphate pathway","type":"exact"},{"name":"regulation of pentose phosphate shunt","type":"exact"},{"name":"regulation of pentose-phosphate pathway","type":"exact"}],"termid":"GO:0043456","terms_by_termid":{"GO:0043456":null,"GO:1905857":null}}


id: PBO:0075663
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spectrin beta, non-erythrocytic 4","termid":"PBO:0075663"}


id: PBO:0043432
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CNIH3 antisense RNA 1","termid":"PBO:0043432"}


id: GO:0039548
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.","definition_xrefs":["PMID:21632562"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway","termid":"GO:0039537"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity","secondary_identifiers":["VZ:757"],"synonyms":[{"name":"inhibition of IRF3-dependent antiviral response","type":"related"},{"name":"inhibition of host IRF3 by virus","type":"related"},{"name":"suppression by virus of host IRF3 activity","type":"related"},{"name":"suppression by virus of host interferon regulatory factor 3","type":"related"},{"name":"suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity","type":"narrow"}],"termid":"GO:0039548"}


id: PR:O14263
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPAC7D4.08 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O14263"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein C7D4.08 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC7D4.08","synonyms":[{"name":"Spom972h-SPAC7D4.08","type":"exact"}],"termid":"PR:O14263"}


id: GO:0102025
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).","definition_xrefs":["GOC:mlg","GOC:pz"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thiosulfate transmembrane transporter activity","termid":"GO:0015117"},{"relation_name":"is_a","term_name":"ATPase-coupled inorganic anion transmembrane transporter activity","termid":"GO:0043225"},{"relation_name":"is_a","term_name":"ABC-type transporter activity","termid":"GO:0140359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"ABC-type thiosulfate transporter activity","secondary_identifiers":["GO:0032146","RHEA:29871","MetaCyc:ABC-7-RXN"],"synonyms":[{"name":"ATPase-coupled thiosulfate transmembrane transporter activity","type":"related"},{"name":"thiosulfate transmembrane-transporting ATPase activity","type":"related"},{"name":"thiosulphate ABC transporter activity","type":"exact"}],"termid":"GO:0102025"}


id: GO:0045195
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of gallstones, hard, crystal-like accretions of cholesterol and bile pigments which develop when bile contains too much cholesterol and not enough bile.","gene_count":0,"genotype_count":0,"name":"obsolete gallstone formation (obsolete GO:0045195)","synonyms":[{"name":"gallstone formation","type":"exact"}],"termid":"GO:0045195"}


id: PBO:0040049
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"actin related protein 2/3 complex subunit 1B","termid":"PBO:0040049"}


id: GO:0090673
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The binding of an endothelial cell to the extracellular matrix via adhesion molecules.","definition_xrefs":["GOC:BHF","GOC:BHF_miRNA","GOC:bc","PMID:19460962"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-matrix adhesion","termid":"GO:0007160"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0007155"}],"interesting_parent_ids":["GO:0008150","GO:0007155"],"is_obsolete":false,"name":"endothelial cell-matrix adhesion","termid":"GO:0090673"}


id: GO:0050531
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.","definition_xrefs":["RHEA:19309","EC:3.1.3.70"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatase activity","termid":"GO:0016791"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003824","GO:0016788","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"mannosyl-3-phosphoglycerate phosphatase activity","secondary_identifiers":["MetaCyc:3.1.3.70-RXN","KEGG_REACTION:R05790"],"synonyms":[{"name":"alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity","type":"related"}],"termid":"GO:0050531"}


id: MONDO:0008318
data:
  {"annotated_genes":["SJAG_04206","SJAG_04394","SJAG_02426"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88282,88283,88284],"is_not":false,"summary":null,"term":"MONDO:0008318"}]},"cv_name":"mondo","definition":"Proteus syndrome (PS) is a very rare and complex hamartomatous overgrowth disorder characterized by progressive overgrowth of the skeleton, skin, adipose, and central nervous systems.","definition_xrefs":["Orphanet:744"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete syndrome or malformation associated with head and neck malformations (obsolete MONDO:0015501)","termid":"MONDO:0015501"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"PTEN hamartoma tumor syndrome","termid":"MONDO:0017623"},{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"},{"relation_name":"is_a","term_name":"overgrowth syndrome","termid":"MONDO:0019716"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02426":null,"SJAG_04206":null,"SJAG_04394":null},"genotype_count":0,"is_obsolete":false,"name":"Proteus syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["NCIT:C85032","OMIM:176920","icd11.foundation:760267333","MESH:D016715","SCTID:23150001","GARD:7475","MEDGEN:39008","ICD9:759.89","UMLS:C0085261","DOID:13482"],"synonyms":[{"name":"Elattoproteus syndrome","type":"related"},{"name":"Proteus syndrome","type":"exact"},{"name":"Wiedemann's syndrome","type":"exact"},{"name":"gigantism, partial, of hands and feet, nevi, hemihypertrophy, and macrocephaly","type":"related"},{"name":"hemihypertrophy and macrocephaly","type":"related"},{"name":"partial gigantism of hands and feet, nevi, hemihypertrophy, macrocephaly","type":"related"},{"name":"partial gigantism-nevi-hemihypertrophy-macrocephaly syndrome","type":"exact"},{"name":"proteus syndrome, somatic","type":"exact"}],"termid":"MONDO:0008318","terms_by_termid":{"MONDO:0008318":null},"xrefs":{"Monarch":{"xref_id":"0008318"}}}


id: RO:0002515
data:
  {"annotation_feature_type":"gene","cv_name":"relationship","definition":"x is sequentially adjacent to y iff x and y do not overlap and if there are no base units intervening between x and y","direct_ancestors":[{"relation_name":"is_a","term_name":"does_not_overlap_sequence_of","termid":"RO:0002527"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sequentially_adjacent_to","termid":"RO:0002515"}


id: PBO:0064473
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA polymerase epsilon 4, accessory subunit","termid":"PBO:0064473"}


id: SO:0000646
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. siRNAs trigger the cleavage of their target molecules.","definition_xrefs":["PMID:12592000"],"direct_ancestors":[{"relation_name":"is_a","term_name":"small_regulatory_ncRNA","termid":"SO:0000370"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"siRNA","secondary_identifiers":["http://en.wikipedia.org/wiki/SiRNA"],"synonyms":[{"name":"INSDC_feature:ncRNA","type":"broad"},{"name":"INSDC_qualifier:siRNA","type":"exact"},{"name":"small interfering RNA","type":"exact"}],"termid":"SO:0000646"}


id: GO:0006112
data:
  {"annotated_genes":["SJAG_00570","SJAG_01080","SJAG_00963","SJAG_00132","SJAG_06309","SJAG_02178","SJAG_02076","SJAG_03964","SJAG_03442","SJAG_03851","SJAG_01376","SJAG_04963","SJAG_01783","SJAG_01561","SJAG_01089","SJAG_00115","SJAG_01319"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[90924,97648,108603,113748,116492,117834],"is_not":false,"summary":null,"term":"GO:0006112"},{"annotations":[105204],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005980"},{"annotations":[81971,74308],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005977"},{"annotations":[75151,80639,81658,73837,74859,73575],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061723"},{"annotations":[78867,80809],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:0045719"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"energy derivation by oxidation of organic compounds","termid":"GO:0015980"}],"gene_count":17,"genes_by_uniquename":{"SJAG_00115":null,"SJAG_00132":null,"SJAG_00570":null,"SJAG_00963":null,"SJAG_01080":null,"SJAG_01089":null,"SJAG_01319":null,"SJAG_01376":null,"SJAG_01561":null,"SJAG_01783":null,"SJAG_02076":null,"SJAG_02178":null,"SJAG_03442":null,"SJAG_03851":null,"SJAG_03964":null,"SJAG_04963":null,"SJAG_06309":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006091","GO:0008150"],"is_obsolete":false,"name":"energy reserve metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"energy reserve metabolism","type":"exact"}],"termid":"GO:0006112","terms_by_termid":{"GO:0005977":null,"GO:0005980":null,"GO:0006112":null,"GO:0045719":null,"GO:0061723":null}}


id: PBO:0047449
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Fc gamma receptor IIIb","termid":"PBO:0047449"}


id: PBO:0057933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MIR3659 host gene","termid":"PBO:0057933"}


id: MOD:01801
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-serine residue to an L-serinium (protonated L-serine).","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-serine residue","termid":"MOD:00916"},{"relation_name":"is_a","term_name":"alpha-amino protonated residue","termid":"MOD:01700"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protonated L-serine (L-serinium) residue","termid":"MOD:01801"}


id: MONDO:0008537
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"eyelid disorder","termid":"MONDO:0003382"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"telecanthus","secondary_identifiers":["MEDGEN:140836","Orphanet:98575","OMIM:187350","GARD:19505","UMLS:C0423113","MESH:C562941","icd11.foundation:210416501"],"synonyms":[{"name":"telecanthus","type":"exact"}],"termid":"MONDO:0008537","xrefs":{"Monarch":{"xref_id":"0008537"}}}


id: GO:0003409
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure.","definition_xrefs":["GOC:dph","GOC:tb","GOC:ascb_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure arrangement","termid":"GO:0048532"},{"relation_name":"part_of","term_name":"optic cup morphogenesis involved in camera-type eye development","termid":"GO:0002072"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"optic cup structural organization","synonyms":[{"name":"optic cup structural organisation","type":"exact"}],"termid":"GO:0003409"}


id: PBO:0001657
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"retinitis pigmentosa","termid":"PBO:0001657"}


id: GO:0061196
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"tongue development","termid":"GO:0043586"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"fungiform papilla development","termid":"GO:0061196"}


id: MOD:01176
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-lysine residue and an L-lysine residue converted to allysine with a carbon-nitrogen bond to form L-dehydrolysinonorleucine.","definition_xrefs":["PubMed:16929109","RESID:AA0430"],"direct_ancestors":[{"relation_name":"is_a","term_name":"uncategorized crosslinked residues","termid":"MOD:00692"},{"relation_name":"is_a","term_name":"crosslinked L-lysine residue","termid":"MOD:02051"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-dehydrolysinonorleucine","synonyms":[{"name":"(2S)-2-amino-6-([(5S)-5-amino-5-carboxypentylidene]amino)hexanoic acid","type":"exact"},{"name":"6-(N6-L-didehydrolysino)-L-norleucine","type":"exact"},{"name":"CROSSLNK Dehydrolysinonorleucine (Lys-Lys)","type":"exact"},{"name":"L-dehydrolysinonorleucine","type":"exact"},{"name":"N6-[(5S)-5-amino-5-carboxypentylidene]-L-lysine","type":"exact"},{"name":"XLNK6NleN6Lys","type":"exact"},{"name":"dehydrolysinorleucine [misspelling]","type":"exact"},{"name":"dehydrolysylnorleucine","type":"exact"},{"name":"didehydrolysinonorleucine","type":"exact"}],"termid":"MOD:01176"}


id: GO:0071753
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.","definition_xrefs":["GOC:add","ISBN:0781765196","PMID:20176268"],"direct_ancestors":[{"relation_name":"is_a","term_name":"immunoglobulin complex","termid":"GO:0019814"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0032991","GO:0005575"],"is_obsolete":false,"name":"IgM immunoglobulin complex","termid":"GO:0071753"}


id: MONDO:0018597
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A lymphatic flow disorder that causes severe respiratory issues. In children with plastic bronchitis, lymph fluid builds in the airways and forms rubbery or caulk-like plugs (known as casts). These casts block the airways, making it difficult to breathe.","direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system disorder","termid":"MONDO:0005087"},{"relation_name":"is_a","term_name":"lymphatic system disorder","termid":"MONDO:0005833"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"plastic bronchitis","secondary_identifiers":["Orphanet:439881","UMLS:C0264342","GARD:21835","MEDGEN:538495","SCTID:53926002"],"synonyms":[{"name":"croupous bronchitis","type":"exact"},{"name":"fibrinous bronchitis","type":"exact"},{"name":"pseudo-membranous bronchitis","type":"exact"}],"termid":"MONDO:0018597","xrefs":{"Monarch":{"xref_id":"0018597"}}}


id: MONDO:0800429
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dyslexia, susceptibility to, 4","secondary_identifiers":["MEDGEN:338829","UMLS:C1851968"],"synonyms":[{"name":"DYX4","type":"exact"}],"termid":"MONDO:0800429","xrefs":{"Monarch":{"xref_id":"0800429"}}}


id: PBO:0003997
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA polymerase zeta Rev7 (predicted)","termid":"PBO:0003997"}


id: PBO:0072154
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S15a pseudogene 31","termid":"PBO:0072154"}


id: _global:ecologically_related_to
data:
  {"annotation_feature_type":"gene","cv_name":"external","definition":"A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ecologically_related_to","secondary_identifiers":["RO:0002321"],"termid":"_global:ecologically_related_to"}


id: MONDO:0029144
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"extraoral halitosis due to methanethiol oxidase deficiency","secondary_identifiers":["MEDGEN:1648340","OMIM:618148","UMLS:C4748387"],"synonyms":[{"name":"EHMTO","type":"related"},{"name":"EXTRAORAL HALITOSIS DUE TO METHANETHIOL OXIDASE DEFICIENCY","type":"related"},{"name":"METHANETHIOL Oxidase Deficiency","type":"related"},{"name":"MTO Deficiency","type":"related"},{"name":"extraoral halitosis due to MTO deficiency","type":"exact"},{"name":"extraoral halitosis with dimethylsulfoxiduria","type":"related"}],"termid":"MONDO:0029144","xrefs":{"Monarch":{"xref_id":"0029144"}}}


id: PBO:0043224
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chloride channel accessory 3, pseudogene","termid":"PBO:0043224"}


id: GO:0031535
data:
  {"annotated_genes":["SJAG_01613","SJAG_03073"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[101113],"is_not":false,"summary":null,"term":"GO:0031535"},{"annotations":[103341],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:0062168"}]},"cv_name":"biological_process","definition":"The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.","definition_xrefs":["GOC:vw","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"microtubule sliding","termid":"GO:0051012"}],"gene_count":2,"genes_by_uniquename":{"SJAG_01613":null,"SJAG_03073":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"plus-end directed microtubule sliding","references_by_uniquename":{"GO_REF:0000107":null},"termid":"GO:0031535","terms_by_termid":{"GO:0031535":null,"GO:0062168":null}}


id: GO:0039577
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1.","definition_xrefs":["PMID:12620806"],"gene_count":0,"genotype_count":0,"name":"obsolete suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation (obsolete GO:0039577)","termid":"GO:0039577"}


id: PR:P79058
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- mug134 gene.","definition_xrefs":["UniProtKB:P79058","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA stability protein mug134 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC10F6.16","synonyms":[{"name":"Spom972h-mug134","type":"exact"},{"name":"initiation of G zero protein 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P79058"}


id: GO:0022843
data:
  {"annotated_genes":["SJAG_05229"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[76209],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0008331"}]},"cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.","definition_xrefs":["ISBN:0815340729","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"voltage-gated monoatomic ion channel activity","termid":"GO:0005244"},{"relation_name":"is_a","term_name":"monoatomic cation channel activity","termid":"GO:0005261"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05229":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0022857","GO:0003674","GO:0005215"],"is_obsolete":false,"name":"voltage-gated monoatomic cation channel activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-2534378","Reactome:R-HSA-6788999"],"synonyms":[{"name":"voltage-gated cation channel activity","type":"broad"}],"termid":"GO:0022843","terms_by_termid":{"GO:0008331":null}}


id: PBO:0044920
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DiGeorge syndrome critical region gene 6","termid":"PBO:0044920"}


id: GO:0099038
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaflet of a membrane, using energy from the hydrolysis of ATP.","definition_xrefs":["GOC:dos","GOC:BHF","GOC:rl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sphingolipid floppase activity","termid":"GO:0046623"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0140303"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0140303"],"is_obsolete":false,"name":"ceramide floppase activity","synonyms":[{"name":"ATP-dependent ceramide transporter activity","type":"broad"},{"name":"ATPase-coupled ceramide transporter activity","type":"broad"},{"name":"ceramide floppase activity (cytosolic to exoplasmic leaflet)","type":"exact"},{"name":"ceramide-translocating ATPase activity","type":"broad"}],"termid":"GO:0099038"}


id: PBO:0084367
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Lipid binding protein; binds to both free fatty acids with preference for saturated long-chain fatty acids and to sterols; contains two independent lipid-binding sites; involved in the export of free fatty acids and acetylated sterols; export functions are redundant with PRY2, and PRY3; important for survival of cells that accumulate free fatty acids; involved in detoxification  of hydrophobic compounds; secreted glycoprotein and member of the CAP/SCP protein superfamily","termid":"PBO:0084367"}


id: GO:0030839
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein polymerization","termid":"GO:0032271"},{"relation_name":"is_a","term_name":"regulation of intermediate filament polymerization or depolymerization","termid":"GO:0045108"},{"relation_name":"regulates","term_name":"intermediate filament polymerization","termid":"GO:0045107"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044085"},{"rel_name":"regulates","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0065003","GO:0008150","GO:0044085"],"is_obsolete":false,"name":"regulation of intermediate filament polymerization","termid":"GO:0030839"}


id: GO:1904897
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","PMID:15358192"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of fibroblast proliferation","termid":"GO:0048145"},{"relation_name":"regulates","term_name":"hepatic stellate cell proliferation","termid":"GO:1990922"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of hepatic stellate cell proliferation","synonyms":[{"name":"regulation of Ito cell proliferation","type":"exact"},{"name":"regulation of hepatic perisinusoidal cell proliferation","type":"exact"},{"name":"regulation of perisinusoidal cell proliferation","type":"exact"}],"termid":"GO:1904897"}


id: GO:0002727
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of natural killer cell mediated immunity","termid":"GO:0002715"},{"relation_name":"is_a","term_name":"regulation of cytokine production involved in immune response","termid":"GO:0002718"},{"relation_name":"regulates","term_name":"natural killer cell cytokine production","termid":"GO:0002370"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0008150","GO:0010467"],"is_obsolete":false,"name":"regulation of natural killer cell cytokine production","synonyms":[{"name":"regulation of NK cell cytokine production","type":"exact"}],"termid":"GO:0002727"}


id: PBO:0011447
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"exocyst complex subunit Sec3","termid":"PBO:0011447"}


id: GO:0150166
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of histone H3-K4 acetylation.","definition_xrefs":["GOC:aruk"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of histone H3-K4 acetylation (obsolete GO:0150166)","termid":"GO:0150166"}


id: PBO:0071062
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L21 pseudogene 64","termid":"PBO:0071062"}


id: GO:0019451
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-cysteine catabolic process to pyruvate","termid":"GO:0019450"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044281","GO:0006790","GO:0008150","GO:0006520"],"is_obsolete":false,"name":"L-cysteine catabolic process to pyruvate, using cysteine dioxygenase","secondary_identifiers":["MetaCyc:CYSTEINE-DEG-PWY"],"synonyms":[{"name":"L-cysteine breakdown to pyruvate, using cysteine dioxygenase","type":"exact"},{"name":"L-cysteine degradation to pyruvate, using cysteine dioxygenase","type":"exact"}],"termid":"GO:0019451"}


id: GO:0018345
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The covalent attachment of a palmitoyl group to a protein.","definition_xrefs":["PMID:15520806","GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein lipidation","termid":"GO:0006497"},{"relation_name":"is_a","term_name":"protein acylation","termid":"GO:0043543"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0042158"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0042158"],"is_obsolete":false,"name":"protein palmitoylation","secondary_identifiers":["GO:0018318","GO:0018349"],"synonyms":[{"name":"protein amino acid palmitoylation","type":"exact"}],"termid":"GO:0018345"}


id: GO:0036312
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location.","definition_xrefs":["GOC:bf","PMID:20505341"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphatidylinositol 3-kinase binding","termid":"GO:0043548"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0005515"}],"interesting_parent_ids":["GO:0003674","GO:0005488","GO:0005515"],"is_obsolete":false,"name":"phosphatidylinositol 3-kinase regulatory subunit binding","synonyms":[{"name":"PI3K regulatory subunit binding","type":"exact"},{"name":"p85 binding","type":"related"}],"termid":"GO:0036312"}


id: PBO:0025444
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"organic aciduria","termid":"PBO:0025444"}


id: PBO:0049342
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GTF2I antisense RNA 1","termid":"PBO:0049342"}


id: PBO:0088190
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Zinc-finger protein of unknown function; possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids; STP3 has a paralog, STP4, that arose from the whole genome duplication","termid":"PBO:0088190"}


id: FYPO:0006928
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which one or both nuclear membrane(s) form blebs. Membrane blebbing usually leads to decreases in nuclear size and the nucleus:cytoplasm volume ratio.","definition_xrefs":["PMID:31015410","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal nuclear envelope morphology during vegetative growth","termid":"FYPO:0000769"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002403"},{"rel_name":"output_of","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0002403","FYPO:0000002","FYPO:0005447"],"is_obsolete":false,"name":"nuclear membrane blebbing","synonyms":[{"name":"nuclear envelope blebbing","type":"related"},{"name":"nuclear membrane blebbing during mitotic cell cycle","type":"related"},{"name":"nuclear membrane blebbing during vegetative growth","type":"exact"}],"termid":"FYPO:0006928"}


id: PBO:0043656
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"COPI coat complex subunit zeta 2","termid":"PBO:0043656"}


id: MONDO:0000579
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete coronin-1A deficiency (obsolete MONDO:0000579)","termid":"MONDO:0000579","xrefs":{"Monarch":{"xref_id":"0000579"}}}


id: PBO:0049917
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hes related family bHLH transcription factor with YRPW motif 2","termid":"PBO:0049917"}


id: SO:0000633
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An mRNA with either a single protein product, or for which the regions encoding all its protein products overlap.","definition_xrefs":["SO:rd"],"direct_ancestors":[{"relation_name":"has_quality","term_name":"monocistronic","termid":"SO:0000878"},{"relation_name":"is_a","term_name":"mRNA","termid":"SO:0000234"},{"relation_name":"is_a","term_name":"monocistronic_transcript","termid":"SO:0000665"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"monocistronic_mRNA","secondary_identifiers":["http://en.wikipedia.org/wiki/Monocistronic_mRNA"],"synonyms":[{"name":"monocistronic mRNA","type":"exact"},{"name":"monocistronic processed transcript","type":"exact"}],"termid":"SO:0000633"}


id: GO:1902886
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity.","definition_xrefs":["PMID:23995839","GOC:di","GOC:TermGenie","GO_REF:0000059"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of proteasome-activating ATPase activity (obsolete GO:1902886)","synonyms":[{"name":"down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"down regulation of proteasomal ATPase activity","type":"exact"},{"name":"down regulation of proteasome channel gating activity","type":"narrow"},{"name":"down regulation of proteasome channel opening activity","type":"narrow"},{"name":"down regulation of proteasome-activating ATPase activity","type":"exact"},{"name":"down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"down-regulation of proteasomal ATPase activity","type":"exact"},{"name":"down-regulation of proteasome channel gating activity","type":"narrow"},{"name":"down-regulation of proteasome channel opening activity","type":"narrow"},{"name":"down-regulation of proteasome-activating ATPase activity","type":"exact"},{"name":"downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"downregulation of proteasomal ATPase activity","type":"exact"},{"name":"downregulation of proteasome channel gating activity","type":"narrow"},{"name":"downregulation of proteasome channel opening activity","type":"narrow"},{"name":"downregulation of proteasome-activating ATPase activity","type":"exact"},{"name":"inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"narrow"},{"name":"inhibition of proteasomal ATPase activity","type":"narrow"},{"name":"inhibition of proteasome channel gating activity","type":"narrow"},{"name":"inhibition of proteasome channel opening activity","type":"narrow"},{"name":"inhibition of proteasome-activating ATPase activity","type":"narrow"},{"name":"negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process","type":"exact"},{"name":"negative regulation of proteasomal ATPase activity","type":"exact"},{"name":"negative regulation of proteasome channel gating activity","type":"narrow"},{"name":"negative regulation of proteasome channel opening activity","type":"narrow"}],"termid":"GO:1902886"}


id: MONDO:0024658
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A malignant soft tissue neoplasm that arises from the extrahepatic bile ducts. Representative examples include Kaposi sarcoma, leiomyosarcoma, and rhabdomyosarcoma.","definition_xrefs":["NCIT:C5029"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bile duct sarcoma","termid":"MONDO:0002862"},{"relation_name":"is_a","term_name":"malignant tumor of extrahepatic bile duct","termid":"MONDO:0021321"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0002515","MONDO:0004335","MONDO:0004992"],"is_obsolete":false,"name":"extrahepatic bile duct sarcoma","secondary_identifiers":["MEDGEN:473546","UMLS:C2205442"],"synonyms":[{"name":"extrahepatic bile duct sarcoma","type":"exact"},{"name":"sarcoma of extrahepatic bile duct","type":"exact"},{"name":"sarcoma of the extrahepatic bile duct","type":"exact"}],"termid":"MONDO:0024658","xrefs":{"Monarch":{"xref_id":"0024658"}}}


id: PBO:0087000
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rho-family GTPase interacting protein and Cdc42p effector; required with Gic1p for cell polarity establishment and initiation of budding; involved in recruitment of septins to the presumptive bud site; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region; gic1 gic2 double mutants are defective for polarizing Cdc42p at elevated temperature, so may function both up- and downstream of Cdc42p; regulates mitotic exit","termid":"PBO:0087000"}


id: PBO:0057036
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 129-2","termid":"PBO:0057036"}


id: GO:0001088
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.","definition_xrefs":["GOC:txnOH"],"gene_count":0,"genotype_count":0,"name":"obsolete transcription factor activity, TFIIE-class binding (obsolete GO:0001088)","synonyms":[{"name":"TFIIE-class binding transcription factor activity","type":"exact"}],"termid":"GO:0001088"}


id: MONDO:0004536
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete villoglandular variant cervical mucinous adenocarcinoma (obsolete MONDO:0004536)","termid":"MONDO:0004536","xrefs":{"Monarch":{"xref_id":"0004536"}}}


id: PBO:0028314
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_localization_to_chromatin_at_LTRs","termid":"PBO:0028314"}


id: PBO:0068134
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 441","termid":"PBO:0068134"}


id: PR:000050570
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A septation initiation network scaffold protein cdc11 (Schizosaccharomyces pombe) that includes phosphorylated residues at a level greater than the interphase-observed phosphorylated form, and is only observed during mitotic anaphase.","definition_xrefs":["PomBase:VW","PMID:12546793","PRO:DAN"],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cdc11/HyperPhos","pombase_gene_id":"SPCC1739.11c","synonyms":[{"name":"PomBase_original_PRO_term_name: septation initiation network scaffold protein cdc11 hyperphosphorylated form (Schizosaccharomyces pombe)","type":"exact"},{"name":"Spom-cdc11/HyperPhos+","type":"exact"},{"name":"cdc11/HyperPhos","type":"exact"},{"name":"cdc11p hyperphosphorylated form (3) (Schizosaccharomyces pombe)","type":"related"}],"termid":"PR:000050570"}


id: PBO:0114413
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Schizosaccharomyces specific microprotein Tam12","termid":"PBO:0114413"}


id: GO:0030312
data:
  {"annotated_genes":["SJAG_00340","SJAG_00620","SJAG_03824","SJAG_00239","SJAG_04864","SJAG_02478","SJAG_02945","SJAG_01321","SJAG_00096","SJAG_01290","SJAG_01086","SJAG_02192","SJAG_06622","SJAG_06621","SJAG_03057","SJAG_01970","SJAG_01288","SJAG_01975","SJAG_03903","SJAG_04073","SJAG_03013","SJAG_00218","SJAG_02649","SJAG_01017","SJAG_04236","SJAG_00784","SJAG_01835","SJAG_03295","SJAG_02135","SJAG_04184","SJAG_04327","SJAG_02222","SJAG_00876","SJAG_04771","SJAG_03483","SJAG_03828","SJAG_01755","SJAG_02916","SJAG_04238","SJAG_03204","SJAG_04720","SJAG_02093","SJAG_04067","SJAG_00027","SJAG_04723","SJAG_01028","SJAG_05285","SJAG_02131"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[119779,116350,111016,92068,116056],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005619"},{"annotations":[58655,65184],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0043188"},{"annotations":[93606],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0005631"},{"annotations":[90506],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0010339"},{"annotations":[104618,108785,104874,104873,118550],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0070263"},{"annotations":[75108,74275,116734,110861,73067,110859,110863,91943,93430,110862,79684,116455,117609,91746,108621,110857,95860,115307,120347,76272,104350,75280,108026,78445,110860,119771,110858,103408,78202,115308,117586],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009277"},{"annotations":[89318],"is_not":false,"rel_names":["part_of"],"summary":null,"term":"GO:0005632"},{"annotations":[89433,117801,89432],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0031160"}]},"cv_name":"cellular_component","definition":"A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular anatomical structure","termid":"GO:0110165"},{"relation_name":"part_of","term_name":"cell periphery","termid":"GO:0071944"}],"gene_count":48,"genes_by_uniquename":{"SJAG_00027":null,"SJAG_00096":null,"SJAG_00218":null,"SJAG_00239":null,"SJAG_00340":null,"SJAG_00620":null,"SJAG_00784":null,"SJAG_00876":null,"SJAG_01017":null,"SJAG_01028":null,"SJAG_01086":null,"SJAG_01288":null,"SJAG_01290":null,"SJAG_01321":null,"SJAG_01755":null,"SJAG_01835":null,"SJAG_01970":null,"SJAG_01975":null,"SJAG_02093":null,"SJAG_02131":null,"SJAG_02135":null,"SJAG_02192":null,"SJAG_02222":null,"SJAG_02478":null,"SJAG_02649":null,"SJAG_02916":null,"SJAG_02945":null,"SJAG_03013":null,"SJAG_03057":null,"SJAG_03204":null,"SJAG_03295":null,"SJAG_03483":null,"SJAG_03824":null,"SJAG_03828":null,"SJAG_03903":null,"SJAG_04067":null,"SJAG_04073":null,"SJAG_04184":null,"SJAG_04236":null,"SJAG_04238":null,"SJAG_04327":null,"SJAG_04720":null,"SJAG_04723":null,"SJAG_04771":null,"SJAG_04864":null,"SJAG_05285":null,"SJAG_06621":null,"SJAG_06622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"external encapsulating structure","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"termid":"GO:0030312","terms_by_termid":{"GO:0005619":null,"GO:0005631":null,"GO:0005632":null,"GO:0009277":null,"GO:0010339":null,"GO:0031160":null,"GO:0043188":null,"GO:0070263":null}}


id: GO:0062241
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair.","definition_xrefs":["PMID:31635174"],"direct_ancestors":[{"relation_name":"is_a","term_name":"membrane-membrane adaptor activity","termid":"GO:0043495"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0060090"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0030674"}],"interesting_parent_ids":["GO:0060090","GO:0030674","GO:0003674"],"is_obsolete":false,"name":"double strand break-nuclear membrane anchor activity","synonyms":[{"name":"DNA repair factory","type":"related"}],"termid":"GO:0062241"}


id: GO:0160058
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires specialized features of a plant endodermal cell.","definition_xrefs":["PMID:21735349"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation","termid":"GO:0030154"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"plant endodermal cell differentiation","termid":"GO:0160058"}


id: PBO:0071364
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L29 pseudogene 23","termid":"PBO:0071364"}


id: PBO:0043116
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"CIAO2A pseudogene 1","termid":"PBO:0043116"}


id: PBO:0052018
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"JMJD7-PLA2G4B readthrough","termid":"PBO:0052018"}


id: _global:causally_upstream_of_or_within,_negative_effect
data:
  {"annotation_feature_type":"gene","cv_name":"external","direct_ancestors":[{"relation_name":"is_a","term_name":"causally_upstream_of_or_within","termid":"_global:causally_upstream_of_or_within"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"causally_upstream_of_or_within,_negative_effect","secondary_identifiers":["RO:0004046"],"termid":"_global:causally_upstream_of_or_within,_negative_effect"}


id: MONDO:0010222
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"X-linked form of Opitz G/BBB syndrome.","definition_xrefs":["MONDO:patterns/x_linked"],"direct_ancestors":[{"relation_name":"is_a","term_name":"X-linked disease","termid":"MONDO:0000425"},{"relation_name":"is_a","term_name":"Opitz G/BBB syndrome","termid":"MONDO:0017138"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"X-linked Opitz G/BBB syndrome","secondary_identifiers":["Orphanet:306597","MEDGEN:424842","UMLS:C2936904","OMIM:300000"],"synonyms":[{"name":"GBBB1","type":"related"},{"name":"Opitz Bbbg syndrome, type 1","type":"related"},{"name":"Opitz G/BBB syndrome, X-linked","type":"exact"},{"name":"Opitz GBBB syndrome, X-linked","type":"related"},{"name":"Opitz GBBB syndrome, type 1","type":"related"},{"name":"Opitz GBBB syndrome, type I","type":"related"},{"name":"Opitz GBBB syndrome, type I, X-linked recessive","type":"exact"},{"name":"Opitz syndrome","type":"related"},{"name":"Opitz syndrome, X-linked","type":"related"},{"name":"Opitz-G syndrome, type 1","type":"related"},{"name":"X-linked Opitz BBB/G syndrome","type":"exact"},{"name":"X-linked Opitz G/BBB syndrome","type":"exact"},{"name":"X-linked Opitz syndrome","type":"exact"},{"name":"XLOS","type":"exact"},{"name":"hypertelorism with esophageal Abnormality and hypospadias","type":"related"},{"name":"hypertelorism-hypospadias syndrome","type":"related"},{"name":"telecanthus-hypospadias syndrome","type":"related"}],"termid":"MONDO:0010222","xrefs":{"Monarch":{"xref_id":"0010222"}}}


id: GO:0097251
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.","definition_xrefs":["GOC:yaf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"leukotriene biosynthetic process","termid":"GO:0019370"},{"relation_name":"is_a","term_name":"leukotriene B4 metabolic process","termid":"GO:0036102"},{"relation_name":"is_a","term_name":"long-chain fatty acid biosynthetic process","termid":"GO:0042759"},{"relation_name":"is_a","term_name":"fatty acid derivative biosynthetic process","termid":"GO:1901570"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0006629"],"is_obsolete":false,"name":"leukotriene B4 biosynthetic process","synonyms":[{"name":"LTB4 anabolism","type":"exact"},{"name":"LTB4 biosynthesis","type":"exact"},{"name":"LTB4 formation","type":"exact"},{"name":"LTB4 synthesis","type":"exact"},{"name":"leukotriene B4 anabolism","type":"exact"},{"name":"leukotriene B4 biosynthesis","type":"exact"},{"name":"leukotriene B4 formation","type":"exact"},{"name":"leukotriene B4 synthesis","type":"exact"}],"termid":"GO:0097251"}


id: PBO:0083812
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Essential RNA-binding G protein effector of mating response pathway; ligand-activated RNA-binding protein that delivers RNAs involved in polarization and perpetualizing mating signal to shmoo tip during pheromone signaling; Scp160p-mediated RNA trafficking essential for chemotropism and successful mating; mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins","termid":"PBO:0083812"}


id: PBO:0078798
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Asn (anticodon GTT) 16-5","termid":"PBO:0078798"}


id: PBO:0070695
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L8 pseudogene 4","termid":"PBO:0070695"}


id: PBO:0065223
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline rich 5","termid":"PBO:0065223"}


id: GO:0009705
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.","definition_xrefs":["ISBN:0471245208","GOC:mtg_sensu"],"direct_ancestors":[{"relation_name":"is_a","term_name":"vacuolar membrane","termid":"GO:0005774"},{"relation_name":"part_of","term_name":"plant-type vacuole","termid":"GO:0000325"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005773"},{"rel_name":"part_of","termid":"GO:0005737"}],"interesting_parent_ids":["GO:0005773","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"plant-type vacuole membrane","synonyms":[{"name":"membrane of vacuole with cell cycle-independent morphology","type":"exact"},{"name":"tonoplast","type":"exact"},{"name":"vacuolar membrane","type":"broad"}],"termid":"GO:0009705"}


id: PBO:0044202
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cathepsin L family member 3, pseudogene","termid":"PBO:0044202"}


id: PBO:0053926
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1224","termid":"PBO:0053926"}


id: PBO:0078345
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Glu (CTC) 11-1","termid":"PBO:0078345"}


id: MONDO:0850049
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"painful legs and moving toes syndrome","secondary_identifiers":["Orphanet:617440","MEDGEN:1842291","GARD:12706","UMLS:C5680388"],"termid":"MONDO:0850049","xrefs":{"Monarch":{"xref_id":"0850049"}}}


id: PBO:0075807
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small RNA binding exonuclease protection factor La like 6, pseudogene","termid":"PBO:0075807"}


id: GO:0046329
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of MAPK cascade","termid":"GO:0043409"},{"relation_name":"is_a","term_name":"regulation of JNK cascade","termid":"GO:0046328"},{"relation_name":"negatively_regulates","term_name":"JNK cascade","termid":"GO:0007254"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"negatively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"negative regulation of JNK cascade","synonyms":[{"name":"down regulation of JNK cascade","type":"exact"},{"name":"down-regulation of JNK cascade","type":"exact"},{"name":"downregulation of JNK cascade","type":"exact"},{"name":"inhibition of JNK cascade","type":"narrow"}],"termid":"GO:0046329"}


id: PBO:0074803
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 13H","termid":"PBO:0074803"}


id: GO:0052442
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway (obsolete GO:0052442)","synonyms":[{"name":"modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway","type":"exact"},{"name":"modulation of defense-related symbiont JA-mediated signal transduction pathway by organism","type":"exact"}],"termid":"GO:0052442"}


id: PBO:0072702
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RuvB like AAA ATPase 2","termid":"PBO:0072702"}


id: GO:0048735
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structures of a haltere are generated and organized.","definition_xrefs":["GOC:rc","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"imaginal disc-derived appendage morphogenesis","termid":"GO:0035114"},{"relation_name":"is_a","term_name":"post-embryonic appendage morphogenesis","termid":"GO:0035120"},{"relation_name":"part_of","term_name":"haltere disc morphogenesis","termid":"GO:0007481"},{"relation_name":"part_of","term_name":"haltere development","termid":"GO:0007482"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"haltere morphogenesis","termid":"GO:0048735"}


id: GO:1905054
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.","definition_xrefs":["PMID:15919193","PMID:23918386","GO_REF:0000061","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"calcium-induced calcium release activity","termid":"GO:0048763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration","synonyms":[{"name":"calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium levels","type":"exact"}],"termid":"GO:1905054"}


id: SO:0001946
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A kind of histone modification site, whereby the 15th residue (a lysine), from the start of the H2B histone protein is acetylated.","definition_xrefs":["EBI:nj"],"direct_ancestors":[{"relation_name":"is_a","term_name":"histone_2B_acetylation_site","termid":"SO:0002143"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"SO:0000839"}],"interesting_parent_ids":["SO:0000839"],"is_obsolete":false,"name":"H2BK15_acetylation_site","synonyms":[{"name":"H2BK15 acetylation site","type":"exact"},{"name":"H2BK15ac","type":"exact"}],"termid":"SO:0001946"}


id: PBO:0116208
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WD repeat protein, human WDR7 ortholog, implicated vacuolar acidification, autophgy, or vacuole localization","termid":"PBO:0116208"}


id: PBO:0041550
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 18 open reading frame 63","termid":"PBO:0041550"}


id: MONDO:1010199
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Muscular dystrophy, Duchenne type that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscular dystrophy, non-human animal","termid":"MONDO:0024965"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"muscular dystrophy, Duchenne type, non-human animal","secondary_identifiers":["OMIA:001081"],"termid":"MONDO:1010199","xrefs":{"Monarch":{"xref_id":"1010199"}}}


id: PBO:0075954
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"signal transducing adaptor molecule 2","termid":"PBO:0075954"}


id: PBO:0030583
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_vacuolar_threonine_level","termid":"PBO:0030583"}


id: GO:0003171
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the atrioventricular valve over time, from its formation to the mature structure.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"heart valve development","termid":"GO:0003170"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"atrioventricular valve development","synonyms":[{"name":"AV valve development","type":"exact"}],"termid":"GO:0003171"}


id: MONDO:0014474
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any autosomal recessive limb-girdle muscular dystrophy in which the cause of the disease is a mutation in the ISPD gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscular dystrophy-dystroglycanopathy, type C","termid":"MONDO:0000173"},{"relation_name":"is_a","term_name":"autosomal recessive limb-girdle muscular dystrophy","termid":"MONDO:0015152"},{"relation_name":"is_a","term_name":"myopathy caused by variation in CRPPA","termid":"MONDO:0100530"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0024322"},{"rel_name":"is_a","termid":"MONDO:0005336"},{"rel_name":"is_a","termid":"MONDO:0005066"}],"interesting_parent_ids":["MONDO:0005336","MONDO:0006025","MONDO:0002320","MONDO:0005066","MONDO:0024322"],"is_obsolete":false,"name":"autosomal recessive limb-girdle muscular dystrophy type 2U","secondary_identifiers":["DOID:0110295","GARD:17519","OMIM:616052","Orphanet:352479","MEDGEN:1683417","UMLS:C5190987"],"synonyms":[{"name":"ISPD autosomal recessive limb-girdle muscular dystrophy","type":"exact"},{"name":"LGMD2U","type":"exact"},{"name":"MDDGC7","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy caused by mutation in ISPD","type":"exact"},{"name":"autosomal recessive limb-girdle muscular dystrophy due to ISPD deficiency","type":"exact"},{"name":"muscular dystrophy limb-girdle type 2U","type":"exact"},{"name":"muscular dystrophy, limb-girdle, type 2U","type":"related"},{"name":"muscular dystrophy-dystroglycanopathy (limb-girdle) type C7","type":"exact"},{"name":"muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 7","type":"related"}],"termid":"MONDO:0014474","xrefs":{"Monarch":{"xref_id":"0014474"}}}


id: PBO:0072573
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleotide reductase regulatory TP53 inducible subunit M2B","termid":"PBO:0072573"}


id: PBO:0000914
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription factor TFIIIC complex A box associated subunit Sfc1","termid":"PBO:0000914"}


id: PBO:0062368
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 7 subfamily A member 3 pseudogene","termid":"PBO:0062368"}


id: GO:0030463
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete cell aging (sensu Fungi) (obsolete GO:0030463)","synonyms":[{"name":"cell aging (sensu Fungi)","type":"exact"}],"termid":"GO:0030463"}


id: MONDO:0010913
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Caroli disease (CD) is a rare congenital liver disease characterized by non-obstructive cystic dilatations of the intra-hepatic and rarely extra-hepatic bile ducts.","definition_xrefs":["Orphanet:53035"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete hereditary biliary tract disease (obsolete MONDO:0015509)","termid":"MONDO:0015509"},{"relation_name":"is_a","term_name":"non-neoplastic bile duct disorder","termid":"MONDO:0006322"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"Caroli disease","secondary_identifiers":["MESH:D016767","OMIM:600643","MedDRA:10013003","icd11.foundation:1757434239","NCIT:C84619","NANDO:2200934","EFO:1001286","MEDGEN:57924","SCTID:717232005","UMLS:C0162510","DOID:0050876","GARD:6002"],"synonyms":[{"name":"CAROLI disease, isolated","type":"related"},{"name":"Caroli disease isolated","type":"related"},{"name":"congenital polycystic dilatation of intrahepatic bile ducts","type":"related"},{"name":"cystic dilatation of the intrahepatic biliary tree","type":"related"}],"termid":"MONDO:0010913","xrefs":{"Monarch":{"xref_id":"0010913"}}}


id: PBO:0036427
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ubiquitin-like protein modifier for cullin Ned8","termid":"PBO:0036427"}


id: GO:0043499
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Binding to a component on the surface of a eukaryotic cell.","definition_xrefs":["GOC:jl"],"gene_count":0,"genotype_count":0,"name":"obsolete eukaryotic cell surface binding (obsolete GO:0043499)","synonyms":[{"name":"eukaryotic cell surface binding","type":"exact"}],"termid":"GO:0043499"}


id: GO:2000974
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of lymphoid progenitor cell differentiation","termid":"GO:1905457"},{"relation_name":"is_a","term_name":"regulation of pro-B cell differentiation","termid":"GO:2000973"},{"relation_name":"negatively_regulates","term_name":"pro-B cell differentiation","termid":"GO:0002328"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of pro-B cell differentiation","synonyms":[{"name":"negative regulation of pro-B cell development","type":"related"},{"name":"negative regulation of pro-B lymphocyte differentiation","type":"exact"}],"termid":"GO:2000974"}


id: PBO:0078783
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Asn (anticodon GTT) 8-1","termid":"PBO:0078783"}


id: PBO:0039436
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and death domain containing 1A","termid":"PBO:0039436"}


id: PBO:0047648
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FKBP prolyl isomerase 4 pseudogene 1","termid":"PBO:0047648"}


id: MONDO:0018919
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"McCune-Albright syndrome (MAS) is classically defined by the clinical triad of fibrous dysplasia of bone (FD), cafe-au-lait skin spots, and precocious puberty (PP).","definition_xrefs":["Orphanet:562"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"autosomal dominant disease","termid":"MONDO:0000426"},{"relation_name":"excluded_subClassOf","term_name":"obsolete polymalformative genetic syndrome with increased risk of developing cancer (obsolete MONDO:0015945)","termid":"MONDO:0015945"},{"relation_name":"excluded_subClassOf","term_name":"obsolete primary bone dysplasia with disorganized development of skeletal components (obsolete MONDO:0019708)","termid":"MONDO:0019708"},{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"McCune-Albright syndrome","secondary_identifiers":["NANDO:2200412","SCTID:726029005","MESH:D005359","NORD:1413","OMIM:174800","DOID:1858","ICD10CM:Q78.1","icd11.foundation:132749439","GARD:6995","MEDGEN:69164","NCIT:C48627","UMLS:C0242292"],"synonyms":[{"name":"Albright's disease","type":"exact"},{"name":"MAS","type":"exact"},{"name":"McCune Albright Syndrome","type":"exact"},{"name":"McCune Albright syndrome","type":"exact"},{"name":"PFD","type":"related"},{"name":"POFD","type":"related"},{"name":"gonadotropin-independent female-limited sexual precocity","type":"exact"},{"name":"mccune-albright syndrome, somatic, mosaic","type":"exact"},{"name":"polyostotic fibrous dysplasia","type":"related"}],"termid":"MONDO:0018919","xrefs":{"Monarch":{"xref_id":"0018919"}}}


id: GO:0022876
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.","definition_xrefs":["ISBN:0815340729","GOC:mtg_transport"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-N(PI)-phosphohistidine-sugar phosphotransferase activity","termid":"GO:0008982"},{"relation_name":"is_a","term_name":"galactosamine transmembrane transporter activity","termid":"GO:0019196"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0016740","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity","synonyms":[{"name":"galactosamine PTS transporter activity","type":"exact"}],"termid":"GO:0022876"}


id: MONDO:0018467
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Nephropathic infantile cystinosis is the most common and severe form of cystinosis, a metabolic disease characterized by an accumulation of cystine inside the lysosomes that causes damage in different organs and tissues, particularly in the kidneys and eyes.","definition_xrefs":["Orphanet:411629"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete nephropathy secondary to a storage or other metabolic disease (obsolete MONDO:0019743)","termid":"MONDO:0019743"},{"relation_name":"is_a","term_name":"inborn disorder of amino acid transport","termid":"MONDO:0019216"},{"relation_name":"is_a","term_name":"nephropathic cystinosis","termid":"MONDO:0100151"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0002561","MONDO:0005066","MONDO:0004736","MONDO:0006025"],"is_obsolete":false,"name":"nephropathic infantile cystinosis","secondary_identifiers":["UMLS:C3537440","ICD10EXP:E72.0+","NANDO:2201234","SCTID:62332007","GARD:9755","ICD10EXP:N16.3*","MEDGEN:760976","NANDO:1200162"],"synonyms":[{"name":"CTNS","type":"related"},{"name":"cystinosin, defect of","type":"related"},{"name":"cystinosis, atypical nephropathic","type":"related"},{"name":"cystinosis, infantile nephropathic","type":"exact"},{"name":"lysosomal cystine transport protein, defect of","type":"related"},{"name":"nephropathic infantile cystinosis","type":"exact"}],"termid":"MONDO:0018467","xrefs":{"Monarch":{"xref_id":"0018467"}}}


id: MONDO:0018734
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A skin hemangioma characterized by the presence of epidermal hyperplasia.","definition_xrefs":["NCIT:C4299"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin hemangioma","termid":"MONDO:0003110"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"verrucous hemangioma","secondary_identifiers":["ICDO:9142/0","Orphanet:464318","MEDGEN:90802","DOID:470","UMLS:C0334540","GARD:21927"],"synonyms":[{"name":"verrucous keratotic hemangioma","type":"exact"},{"name":"verrucous keratotic hemangioma (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0018734","xrefs":{"Monarch":{"xref_id":"0018734"}}}


id: GO:1900714
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process.","definition_xrefs":["GOC:TermGenie","GOC:di"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of small molecule metabolic process","termid":"GO:0062014"},{"relation_name":"is_a","term_name":"negative regulation of secondary metabolite biosynthetic process","termid":"GO:1900377"},{"relation_name":"is_a","term_name":"regulation of violaceol I biosynthetic process","termid":"GO:1900713"},{"relation_name":"negatively_regulates","term_name":"violaceol I biosynthetic process","termid":"GO:1900590"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"negatively_regulates","termid":"GO:0044281"},{"rel_name":"negatively_regulates","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"regulates","termid":"GO:0019748"}],"interesting_parent_ids":["GO:0019748","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"negative regulation of violaceol I biosynthetic process","synonyms":[{"name":"down regulation of violaceol I anabolism","type":"exact"},{"name":"down regulation of violaceol I biosynthesis","type":"exact"},{"name":"down regulation of violaceol I biosynthetic process","type":"exact"},{"name":"down regulation of violaceol I formation","type":"exact"},{"name":"down regulation of violaceol I synthesis","type":"exact"},{"name":"down-regulation of violaceol I anabolism","type":"exact"},{"name":"down-regulation of violaceol I biosynthesis","type":"exact"},{"name":"down-regulation of violaceol I biosynthetic process","type":"exact"},{"name":"down-regulation of violaceol I formation","type":"exact"},{"name":"down-regulation of violaceol I synthesis","type":"exact"},{"name":"downregulation of violaceol I anabolism","type":"exact"},{"name":"downregulation of violaceol I biosynthesis","type":"exact"},{"name":"downregulation of violaceol I biosynthetic process","type":"exact"},{"name":"downregulation of violaceol I formation","type":"exact"},{"name":"downregulation of violaceol I synthesis","type":"exact"},{"name":"inhibition of violaceol I anabolism","type":"exact"},{"name":"inhibition of violaceol I biosynthesis","type":"exact"},{"name":"inhibition of violaceol I biosynthetic process","type":"narrow"},{"name":"inhibition of violaceol I formation","type":"exact"},{"name":"inhibition of violaceol I synthesis","type":"exact"},{"name":"negative regulation of violaceol I anabolism","type":"exact"},{"name":"negative regulation of violaceol I biosynthesis","type":"exact"},{"name":"negative regulation of violaceol I formation","type":"exact"},{"name":"negative regulation of violaceol I synthesis","type":"exact"}],"termid":"GO:1900714"}


id: MONDO:0019284
data:
  {"annotated_genes":["SJAG_00321"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88279],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007900"}]},"cv_name":"mondo","definition":"A nail anomaly that is not part of a larger syndrome.","definition_xrefs":["MONDO:patterns/isolated"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nail disorder","termid":"MONDO:0002884"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00321":null},"genotype_count":0,"is_obsolete":false,"name":"inherited isolated nail anomaly","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5681477","GARD:19000","DOID:0080683","MEDGEN:1843192","OMIMPS:161050","Orphanet:79369"],"synonyms":[{"name":"isolated nail anomaly","type":"related"},{"name":"nail disorder, nonsyndromic congenital","type":"exact"},{"name":"nonsyndromic nail anomaly","type":"exact"}],"termid":"MONDO:0019284","terms_by_termid":{"MONDO:0007900":null},"xrefs":{"Monarch":{"xref_id":"0019284"}}}


id: PBO:0046893
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"family with sequence similarity 13 member C","termid":"PBO:0046893"}


id: PBO:0046716
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"EVA1C pseudogene 2","termid":"PBO:0046716"}


id: PBO:0087843
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Threonyl-tRNA synthetase; essential cytoplasmic protein; human homolog TARS can complement yeast null mutant","termid":"PBO:0087843"}


id: MONDO:1010558
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Spina bifida that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"spina bifida, non-human animal","termid":"MONDO:1010047"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"spina bifida, cattle","secondary_identifiers":["OMIA:000933-9913"],"termid":"MONDO:1010558","xrefs":{"Monarch":{"xref_id":"1010558"}}}


id: PBO:0074188
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"solute carrier family 38 member 9","termid":"PBO:0074188"}


id: GO:1901241
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.","definition_xrefs":["GOC:TermGenie","PMID:9315705"],"direct_ancestors":[{"relation_name":"is_a","term_name":"monocarboxylic acid transmembrane transporter activity","termid":"GO:0008028"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005215"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"}],"interesting_parent_ids":["GO:0022857","GO:0005215","GO:0003674"],"is_obsolete":false,"name":"4-hydroxyphenylacetate transmembrane transporter activity","termid":"GO:1901241"}


id: PBO:0076827
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"telomerase associated protein 1","termid":"PBO:0076827"}


id: MONDO:0007140
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete antiphospholipid syndrome (obsolete MONDO:0007140)","secondary_identifiers":["NANDO:1200271","NANDO:2200421"],"termid":"MONDO:0007140","xrefs":{"Monarch":{"xref_id":"0007140"}}}


id: MOD:00730
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"a protein modification that effectively replaces a hydrogen atom of an amino acid residue or of a modifying group with a arabinose sugar group through a glycosidic bond","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pentosylated residue","termid":"MOD:00729"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"arabinosylated","synonyms":[{"name":"Ara","type":"exact"}],"termid":"MOD:00730"}


id: PBO:0042408
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cell division cycle 20B","termid":"PBO:0042408"}


id: PBO:0114524
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Set3 complex WD repeat subunit Hif2","termid":"PBO:0114524"}


id: MONDO:0007446
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign skin condition commonly seen in dark-skinned individuals that is characterized by multiple small hyperpigmented papular lesions resembling seborrheic keratosis on the face and upper body.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dermatitis","termid":"MONDO:0002406"},{"relation_name":"is_a","term_name":"hereditary skin disorder","termid":"MONDO:0100118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"dermatosis papulosa nigra","secondary_identifiers":["MESH:C562379","icd11.foundation:168986957","MEDGEN:4238","OMIM:125600","DOID:4400","NCIT:C2984","EFO:1000686","SCTID:254669003","UMLS:C0011645","Wikipedia:Dermatosis_papulosa_nigra","ICD10CM:L82","ICD9:709.8"],"synonyms":[{"name":"dermatosis papulosa nigra","type":"exact"},{"name":"dermatosis papulosa nigra (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0007446","xrefs":{"Monarch":{"xref_id":"0007446"}}}


id: FYPO:0003349
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase B is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart.","definition_xrefs":["GO:1990023","PomBase:mah","GO:0000092"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to mitotic spindle midzone","termid":"FYPO:0004692"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000257","FYPO:0000138","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal protein localization to mitotic spindle midzone during anaphase B","synonyms":[{"name":"normal protein localisation to mitotic spindle midzone during anaphase B","type":"exact"},{"name":"normal protein localization to mitotic spindle midzone during anaphase B during vegetative growth","type":"exact"},{"name":"normal protein localization to spindle midzone during anaphase B during mitotic cell cycle","type":"exact"}],"termid":"FYPO:0003349"}


id: PBO:0016547
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"C1-5,6,7,8-tetrahydrofolate (THF) synthase, trifunctional enzyme Thf1","termid":"PBO:0016547"}


id: PBO:0047980
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FSHD region gene 1 family member G, pseudogene","termid":"PBO:0047980"}


id: GO:0070330
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + testosterone = 17beta-estradiol + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. Also converts androst-4-ene-3,17-dione into estrone.","definition_xrefs":["EC:1.14.14.14"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016712"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"aromatase activity","synonyms":[{"name":"estrogen synthetase activity","type":"narrow"}],"termid":"GO:0070330"}


id: PBO:0053331
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 163","termid":"PBO:0053331"}


id: MONDO:1011518
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Glycogen storage disease that occurs in ring-tailed coati.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycogen storage disease, non-human animal","termid":"MONDO:1011419"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"glycogen storage disease, ring-tailed coati","secondary_identifiers":["OMIA:001883-9651"],"termid":"MONDO:1011518","xrefs":{"Monarch":{"xref_id":"1011518"}}}


id: PBO:0091745
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPBC18H10.16 was previously designated as can1","termid":"PBO:0091745"}


id: MOD:01524
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"The protein modification reporter fragment produced by an Applied Biosystems iTRAQ4plex 116 reagent derivatized residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"derives_from","term_name":"iTRAQ4plex-116 reporter+balance reagent acylated residue","termid":"MOD:01499"},{"relation_name":"is_a","term_name":"iTRAQ4plex reporter fragment","termid":"MOD:01521"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"iTRAQ4plex-116 reporter fragment","synonyms":[{"name":"4-methyl-1-methylidenepiperazin-1-ium","type":"exact"}],"termid":"MOD:01524"}


id: PBO:0005391
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"medial ring protein Mid1","termid":"PBO:0005391"}


id: PBO:0042775
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"centrosomal protein 85","termid":"PBO:0042775"}


id: MONDO:0019701
data:
  {"annotated_genes":["SJAG_02855","SJAG_04810","SJAG_00326","SJAG_00702"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87148],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010621"},{"annotations":[87872],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008974"},{"annotations":[87855],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008972"},{"annotations":[87704],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014743"}]},"cv_name":"mondo","definition":"A rare congenital developmental disorder characterized by the presence of stippled foci of calcification in the hyaline cartilage, joint contractions, mental retardation and ichthyosis.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00326":null,"SJAG_00702":null,"SJAG_02855":null,"SJAG_04810":null},"genotype_count":0,"is_obsolete":false,"name":"chondrodysplasia punctata","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["ICD10CM:Q77.3","icd11.foundation:1923035846","MEDGEN:3052","NANDO:2201017","NCIT:C84632","Orphanet:93442","SCTID:360507004","UMLS:C0008445","DOID:2581","GARD:8542","ICD9:756.59","MESH:D002806"],"synonyms":[{"name":"CDP","type":"exact"},{"name":"chondrodysplasia calcificans congenita","type":"exact"},{"name":"chondrodysplasia punctata (stippled epiphyses) Group","type":"exact"},{"name":"chondrodysplasia punctata congenita","type":"exact"}],"termid":"MONDO:0019701","terms_by_termid":{"MONDO:0008972":null,"MONDO:0008974":null,"MONDO:0010621":null,"MONDO:0014743":null},"xrefs":{"Monarch":{"xref_id":"0019701"}}}


id: PBO:0052254
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KDEL endoplasmic reticulum protein retention receptor 1","termid":"PBO:0052254"}


id: GO:0075509
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any endocytosis that is involved in the uptake of a virus into a host cell.","definition_xrefs":["GOC:jl","VZ:977","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont entry into host cell","termid":"GO:0046718"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endocytosis involved in viral entry into host cell","synonyms":[{"name":"viral entry into host cell via endocytosis","type":"related"},{"name":"viral penetration via endocytosis followed by endosome disruption","type":"exact"},{"name":"virus endocytosis by host","type":"exact"}],"termid":"GO:0075509"}


id: GO:0046855
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process of removing a phosphate group from any mono- or polyphosphorylated inositol.","definition_xrefs":["ISBN:0198506732"],"gene_count":0,"genotype_count":0,"name":"obsolete inositol phosphate dephosphorylation (obsolete GO:0046855)","synonyms":[{"name":"myo-inositol phosphate dephosphorylation","type":"narrow"}],"termid":"GO:0046855"}


id: GO:0050242
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H+ + phosphoenolpyruvate.","definition_xrefs":["RHEA:10756"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phosphotransferase activity, paired acceptors","termid":"GO:0016781"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003674","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"pyruvate, phosphate dikinase activity","secondary_identifiers":["MetaCyc:PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN","EC:2.7.9.1","KEGG_REACTION:R00206"],"synonyms":[{"name":"ATP:pyruvate, phosphate phosphotransferase activity","type":"related"},{"name":"PPDK","type":"related"},{"name":"orthophosphate dikinase pyruvate","type":"related"},{"name":"pyruvate, Pi dikinase activity","type":"related"},{"name":"pyruvate,orthophosphate dikinase activity","type":"related"},{"name":"pyruvate,phosphate dikinase activity","type":"related"},{"name":"pyruvate-inorganic phosphate dikinase activity","type":"related"},{"name":"pyruvate-phosphate dikinase (phosphorylating)","type":"related"},{"name":"pyruvate-phosphate dikinase activity","type":"related"},{"name":"pyruvate-phosphate ligase activity","type":"related"},{"name":"pyruvic-phosphate dikinase activity","type":"related"},{"name":"pyruvic-phosphate ligase activity","type":"related"}],"termid":"GO:0050242"}


id: GO:0010393
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues.","definition_xrefs":["GOC:tair_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide metabolic process","termid":"GO:0005976"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0005975"],"is_obsolete":false,"name":"galacturonan metabolic process","synonyms":[{"name":"galacturonan metabolism","type":"exact"}],"termid":"GO:0010393"}


id: FYPO:0009080
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of calcofluor and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of calcofluor and sodium dodecyl sulfate that allow wild type cells to grow.","direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0002683","FYPO:0005447","FYPO:0000003","FYPO:0000139","FYPO:0001985"],"is_obsolete":false,"name":"sensitive to calcofluor and sodium dodecyl sulfate","synonyms":[{"name":"hypersensitive to calcofluor and SDS","type":"exact"},{"name":"hypersensitive to calcofluor and sodium dodecyl sulfate","type":"exact"},{"name":"sensitive to calcofluor and SDS","type":"exact"},{"name":"sensitive to calcofluor and SDS during vegetative growth","type":"exact"},{"name":"sensitive to calcofluor and SDS in combination","type":"exact"},{"name":"sensitive to calcofluor and sodium dodecyl sulfate during vegetative growth","type":"exact"},{"name":"sensitive to calcofluor and sodium dodecyl sulfate in combination","type":"exact"}],"termid":"FYPO:0009080"}


id: PBO:0026752
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_protein_phosphorylation_during_cellular_response_to_arginine","termid":"PBO:0026752"}


id: PBO:0028539
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_primary_cell_septum_thickness","termid":"PBO:0028539"}


id: GO:0007312
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.","definition_xrefs":["GOC:mah","GOC:mtg_sensu","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nuclear migration","termid":"GO:0007097"},{"relation_name":"is_a","term_name":"oocyte nucleus localization involved in oocyte dorsal/ventral axis specification","termid":"GO:0051663"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0051179"}],"interesting_parent_ids":["GO:0051179","GO:0006810","GO:0008150"],"is_obsolete":false,"name":"oocyte nucleus migration involved in oocyte dorsal/ventral axis specification","secondary_identifiers":["GO:0048126","GO:0048128","GO:0008102","GO:0030722"],"synonyms":[{"name":"establishment of localization of oocyte nucleus during oocyte axis determination","type":"broad"},{"name":"establishment of oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification","type":"related"},{"name":"establishment of oocyte nucleus localization during oocyte axis determination","type":"broad"},{"name":"establishment of oocyte nucleus localization involved in oocyte dorsal-ventral axis specification","type":"related"},{"name":"establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis determination","type":"related"},{"name":"establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification","type":"related"},{"name":"establishment of oocyte nucleus localization involved in oocyte dorsoventral axis specification","type":"related"},{"name":"nucleus positioning in oocyte during oocyte axis determination","type":"broad"},{"name":"oocyte axis determination, establishment of localization of nucleus","type":"broad"},{"name":"oocyte axis determination, establishment of oocyte nucleus localization","type":"broad"},{"name":"oocyte axis determination, establishment of position of nucleus","type":"broad"},{"name":"oocyte axis determination, oocyte nuclear migration","type":"exact"},{"name":"oocyte axis determination, oocyte nucleus migration","type":"exact"},{"name":"oocyte axis determination, positioning of nucleus","type":"broad"},{"name":"oocyte nuclear migration during oocyte axis determination","type":"exact"},{"name":"oocyte nucleus migration during oocyte axis determination","type":"exact"},{"name":"oocyte nucleus migration during oocyte axis specification","type":"related"},{"name":"oocyte nucleus positioning during oocyte axis determination","type":"broad"}],"termid":"GO:0007312"}


id: MONDO:0019547
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Wells syndrome is characterized by the presence of recurrent cellulitis-like eruptions with eosinophilia.","definition_xrefs":["Orphanet:901"],"direct_ancestors":[{"relation_name":"is_a","term_name":"skin disorder","termid":"MONDO:0005093"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"Wells syndrome","secondary_identifiers":["GARD:329","NORD:1124","UMLS:C0343101","MESH:C536693","icd11.foundation:1860796142","SCTID:238931006","ICD9:682.9","MEDGEN:91008"],"synonyms":[{"name":"Familial Eosinophilic Cellulitis","type":"exact"},{"name":"Wells' syndrome","type":"related"},{"name":"bullous cellulitis with eosinophilia","type":"related"},{"name":"eosinophilic cellulitis","type":"exact"}],"termid":"MONDO:0019547","xrefs":{"Monarch":{"xref_id":"0019547"}}}


id: PBO:0055691
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"liver cell viability associated lncRNA","termid":"PBO:0055691"}


id: FYPO:0005392
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) during a cellular response to ionizing radiation.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process during vegetative growth","termid":"FYPO:0001319"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0001312","FYPO:0000257","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"normal DNA recombination frequency during cellular response to ionizing radiation","synonyms":[{"name":"normal DNA recombination frequency during cellular response to IR","type":"exact"},{"name":"normal DNA recombination frequency during cellular response to ionizing radiation during mitotic cell cycle","type":"related"},{"name":"normal DNA recombination frequency during cellular response to ionizing radiation during vegetative growth","type":"exact"}],"termid":"FYPO:0005392"}


id: PBO:0031628
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abolished_sporulation","termid":"PBO:0031628"}


id: PR:O74394
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A 39S ribosomal protein L33, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"54S ribosomal protein L39, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC4F6.08c","secondary_identifiers":["UniProtKB:O74394"],"synonyms":[{"name":"SPBC4F6.08c","type":"related"},{"name":"Spom972h-MRPL33","type":"exact"}],"termid":"PR:O74394"}


id: GO:0004656
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.","definition_xrefs":["EC:1.14.11.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"procollagen-proline dioxygenase activity","termid":"GO:0019798"},{"relation_name":"is_a","term_name":"peptidyl-proline 4-dioxygenase activity","termid":"GO:0031545"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0140096","GO:0016491"],"is_obsolete":false,"name":"procollagen-proline 4-dioxygenase activity","secondary_identifiers":["MetaCyc:1.14.11.2-RXN","RHEA:18945","Reactome:R-HSA-1650808","KEGG_REACTION:R03219"],"synonyms":[{"name":"collagen proline hydroxylase activity","type":"related"},{"name":"hydroxylase, collagen proline activity","type":"related"},{"name":"peptidyl proline hydroxylase activity","type":"broad"},{"name":"procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity","type":"related"},{"name":"procollagen-proline,2-oxoglutarate-4-dioxygenase activity","type":"exact"},{"name":"proline hydroxylase activity","type":"broad"},{"name":"proline protocollagen hydroxylase activity","type":"related"},{"name":"proline, 2-oxoglutarate dioxygenase activity","type":"broad"},{"name":"proline,2-oxoglutarate 4-dioxygenase activity","type":"broad"},{"name":"prolyl 4-hydroxylase activity","type":"broad"},{"name":"prolyl hydroxylase activity","type":"broad"},{"name":"prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity","type":"broad"},{"name":"prolylprotocollagen dioxygenase activity","type":"related"},{"name":"prolylprotocollagen hydroxylase activity","type":"related"},{"name":"protocollagen hydroxylase activity","type":"broad"},{"name":"protocollagen proline 4-hydroxylase activity","type":"related"},{"name":"protocollagen proline dioxygenase activity","type":"related"},{"name":"protocollagen proline hydroxylase activity","type":"related"},{"name":"protocollagen prolyl hydroxylase activity","type":"related"}],"termid":"GO:0004656"}


id: PBO:0068806
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 43, pseudogene","termid":"PBO:0068806"}


id: GO:2000033
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of seed dormancy process.","definition_xrefs":["GOC:pr","GOC:obol","ISBN:9781405139830"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of seed maturation","termid":"GO:2000034"},{"relation_name":"regulates","term_name":"seed dormancy process","termid":"GO:0010162"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of seed dormancy process","synonyms":[{"name":"regulation of seed dormancy","type":"related"}],"termid":"GO:2000033"}


id: GO:0040013
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of locomotion","termid":"GO:0040012"},{"relation_name":"is_a","term_name":"negative regulation of biological process","termid":"GO:0048519"},{"relation_name":"negatively_regulates","term_name":"locomotion","termid":"GO:0040011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of locomotion","synonyms":[{"name":"down regulation of locomotion","type":"exact"},{"name":"down-regulation of locomotion","type":"exact"},{"name":"downregulation of locomotion","type":"exact"},{"name":"inhibition of locomotion","type":"narrow"}],"termid":"GO:0040013"}


id: MONDO:0005154
data:
  {"annotated_genes":["SJAG_05194","SJAG_04956","SJAG_02876","SJAG_01012","SJAG_04944","SJAG_04109","SJAG_03535","SJAG_01950","SJAG_01372","SJAG_01841","SJAG_03961","SJAG_03363","SJAG_02015","SJAG_00409","SJAG_03011","SJAG_02896","SJAG_02049","SJAG_00938","SJAG_00175","SJAG_01166","SJAG_00358"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87348],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013111"},{"annotations":[87132],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008294"},{"annotations":[88602],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011559"},{"annotations":[88849],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013995"},{"annotations":[88787,88786],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0030810"},{"annotations":[87691],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0031040"},{"annotations":[87532],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008296"},{"annotations":[88454],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007256"},{"annotations":[87683],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0007369"},{"annotations":[87738],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0024568"},{"annotations":[86946],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014659"},{"annotations":[88659],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0032844"},{"annotations":[87941],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008265"},{"annotations":[87880],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014860"},{"annotations":[86921],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0054743"},{"annotations":[87278],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013000"},{"annotations":[88725],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011156"},{"annotations":[87358],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0011214"},{"annotations":[86970],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008319"},{"annotations":[88471,88472],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013771"},{"annotations":[87551],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0008297"},{"annotations":[88196],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0957577"},{"annotations":[88534],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0010420"}]},"cv_name":"mondo","definition":"A disease involving the liver.","direct_ancestors":[{"relation_name":"is_a","term_name":"hepatobiliary disorder","termid":"MONDO:0002515"},{"relation_name":"is_a","term_name":"endocrine system disorder","termid":"MONDO:0005151"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00175":null,"SJAG_00358":null,"SJAG_00409":null,"SJAG_00938":null,"SJAG_01012":null,"SJAG_01166":null,"SJAG_01372":null,"SJAG_01841":null,"SJAG_01950":null,"SJAG_02015":null,"SJAG_02049":null,"SJAG_02876":null,"SJAG_02896":null,"SJAG_03011":null,"SJAG_03363":null,"SJAG_03535":null,"SJAG_03961":null,"SJAG_04109":null,"SJAG_04944":null,"SJAG_04956":null,"SJAG_05194":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002515"},{"rel_name":"is_a","termid":"MONDO:0004335"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0002515"],"is_obsolete":false,"name":"liver disorder","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:893061","ICD9:573.9","UMLS:C4021780","MESH:D008107","DOID:409","EFO:0001421","NCIT:C3196","ICD10CM:K70-K77","SCTID:235856003","ICD9:573.8"],"synonyms":[{"name":"disease of liver","type":"exact"},{"name":"disease or disorder of liver","type":"exact"},{"name":"disorder of liver","type":"exact"},{"name":"hepatic disease","type":"exact"},{"name":"hepatic disorder","type":"exact"},{"name":"liver and intrahepatic bile duct disorder","type":"exact"},{"name":"liver disease","type":"exact"},{"name":"liver disease or disorder","type":"exact"},{"name":"liver disorder","type":"exact"}],"termid":"MONDO:0005154","terms_by_termid":{"MONDO:0007256":null,"MONDO:0007369":null,"MONDO:0008265":null,"MONDO:0008294":null,"MONDO:0008296":null,"MONDO:0008297":null,"MONDO:0008319":null,"MONDO:0010420":null,"MONDO:0011156":null,"MONDO:0011214":null,"MONDO:0011559":null,"MONDO:0013000":null,"MONDO:0013111":null,"MONDO:0013771":null,"MONDO:0013995":null,"MONDO:0014659":null,"MONDO:0014860":null,"MONDO:0024568":null,"MONDO:0030810":null,"MONDO:0031040":null,"MONDO:0032844":null,"MONDO:0054743":null,"MONDO:0957577":null},"xrefs":{"Monarch":{"xref_id":"0005154"}}}


id: MONDO:0005202
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms.","definition_xrefs":["NCIT:C41366"],"direct_ancestors":[{"relation_name":"is_a","term_name":"allergic disease","termid":"MONDO:0005271"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"atopic IgE-mediated allergic disorder","secondary_identifiers":["SCTID:115665000","EFO:0002686","UMLS:C1706410","ICD9:995.3","MEDGEN:739536"],"synonyms":[{"name":"Atopic allergy","type":"related"},{"name":"atopic state","type":"related"},{"name":"atopy","type":"related"}],"termid":"MONDO:0005202","xrefs":{"Monarch":{"xref_id":"0005202"}}}


id: GO:0008994
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.","definition_xrefs":["EC:4.1.2.19"],"direct_ancestors":[{"relation_name":"is_a","term_name":"aldehyde-lyase activity","termid":"GO:0016832"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016829"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016829","GO:0003824"],"is_obsolete":false,"name":"rhamnulose-1-phosphate aldolase activity","secondary_identifiers":["MetaCyc:RHAMNULPALDOL-RXN","RHEA:19689"],"synonyms":[{"name":"L-rhamnulose 1-phosphate aldolase activity","type":"related"},{"name":"L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)","type":"related"},{"name":"L-rhamnulose-1-phosphate lactaldehyde-lyase activity","type":"related"},{"name":"L-rhamnulose-phosphate aldolase activity","type":"related"},{"name":"rhamnulose phosphate aldolase activity","type":"related"}],"termid":"GO:0008994"}


id: PR:Q9C103
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- eme1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9C103"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crossover junction endonuclease eme1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAPB1E7.06c","synonyms":[{"name":"Spom972h-eme1","type":"exact"},{"name":"essential meiotic endonuclease 1 (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9C103"}


id: PBO:0056629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mediator complex subunit 9","termid":"PBO:0056629"}


id: GO:0007525
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.","definition_xrefs":["GOC:mtg_muscle","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"muscle structure development","termid":"GO:0061061"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"somatic muscle development","termid":"GO:0007525"}


id: GO:1901982
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to maltose.","definition_xrefs":["GOC:TermGenie","PMID:21566157"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disaccharide binding","termid":"GO:0048030"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0005488"],"is_obsolete":false,"name":"maltose binding","termid":"GO:1901982"}


id: MONDO:0022586
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"skeletal dysplasia","termid":"MONDO:0018230"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"bone dysplasia Moore type","secondary_identifiers":["GARD:923"],"termid":"MONDO:0022586","xrefs":{"Monarch":{"xref_id":"0022586"}}}


id: PBO:0001770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosome biogenesis protein Ltv1 (predicted)","termid":"PBO:0001770"}


id: GO:0000475
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"rRNA processing","termid":"GO:0006364"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"part_of","termid":"GO:0042254"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0010467","GO:0042254","GO:0008150"],"is_obsolete":false,"name":"maturation of 2S rRNA","termid":"GO:0000475"}


id: GO:0045703
data:
  {"annotated_genes":["SJAG_00630"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[70565],"is_not":false,"summary":null,"term":"GO:0045703"}]},"cv_name":"molecular_function","definition":"Catalysis of the reduction of a ketone group to form the corresponding alcohol.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on CH-OH group of donors","termid":"GO:0016614"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00630":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003824","GO:0016491","GO:0003674"],"is_obsolete":false,"name":"ketoreductase activity","references_by_uniquename":{"GO_REF:0000002":null},"termid":"GO:0045703","terms_by_termid":{"GO:0045703":null}}


id: GO:1902568
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of eosinophil activation.","definition_xrefs":["PMID:16254138","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of leukocyte activation","termid":"GO:0002696"},{"relation_name":"is_a","term_name":"regulation of eosinophil activation","termid":"GO:1902566"},{"relation_name":"positively_regulates","term_name":"eosinophil activation","termid":"GO:0043307"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of eosinophil activation","synonyms":[{"name":"activation of eosinophil activation","type":"narrow"},{"name":"up regulation of eosinophil activation","type":"exact"},{"name":"up-regulation of eosinophil activation","type":"exact"},{"name":"upregulation of eosinophil activation","type":"exact"}],"termid":"GO:1902568"}


id: PBO:0031504
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_valinomycin","termid":"PBO:0031504"}


id: PBO:0071966
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein S6 kinase A5","termid":"PBO:0071966"}


id: FYPO:0006242
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication forks stall at a lower frequency in mutant cells than in wild type during a cellular response to DNA damage.","definition_xrefs":["PMID:28806726","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal mitotic DNA replication","termid":"FYPO:0001343"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000631","FYPO:0000002","FYPO:0001985","FYPO:0005447","FYPO:0000293","FYPO:0001320"],"is_obsolete":false,"name":"decreased replication fork stalling during cellular response to DNA damage","synonyms":[{"name":"decreased frequency of replication fork stalling during cellular response to DNA damage","type":"exact"},{"name":"decreased replication fork stalling during cellular response to DNA damage during mitotic cell cycle","type":"related"},{"name":"decreased replication fork stalling during cellular response to DNA damage during vegetative growth","type":"exact"},{"name":"reduced replication fork stalling during cellular response to DNA damage","type":"exact"}],"termid":"FYPO:0006242"}


id: PBO:0071298
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L26 pseudogene 21","termid":"PBO:0071298"}


id: GO:0010510
data:
  {"annotated_genes":["SJAG_01402"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[76916],"is_not":false,"summary":null,"term":"GO:0010510"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.","definition_xrefs":["GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of acyl-CoA biosynthetic process","termid":"GO:0050812"},{"relation_name":"regulates","term_name":"pyruvate decarboxylation to acetyl-CoA","termid":"GO:0006086"}],"gene_count":1,"genes_by_uniquename":{"SJAG_01402":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0055086"},{"rel_name":"regulates","termid":"GO:0006790"},{"rel_name":"regulates","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0055086","GO:0006629","GO:0006790"],"is_obsolete":false,"name":"regulation of pyruvate decarboxylation to acetyl-CoA","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-204174"],"synonyms":[{"name":"regulation of acetyl-CoA biosynthetic process from pyruvate","type":"exact"}],"termid":"GO:0010510","terms_by_termid":{"GO:0010510":null}}


id: PR:Q9Y7Q6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- set7 gene.","definition_xrefs":["UniProtKB:Q9Y7Q6","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SET domain-containing protein 7 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC297.04c","synonyms":[{"name":"Spom972h-set7","type":"exact"}],"termid":"PR:Q9Y7Q6"}


id: GO:2000479
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.","definition_xrefs":["GOC:obol"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein serine/threonine kinase activity","termid":"GO:0071900"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of cAMP-dependent protein kinase activity","synonyms":[{"name":"regulation of 3',5' cAMP-dependent protein kinase activity","type":"exact"},{"name":"regulation of 3',5'-cAMP-dependent protein kinase activity","type":"exact"},{"name":"regulation of AMPK","type":"related"},{"name":"regulation of ATP:protein phosphotransferase (cAMP-dependent) activity","type":"exact"},{"name":"regulation of PKA","type":"related"},{"name":"regulation of PKA C","type":"related"},{"name":"regulation of STK22","type":"related"},{"name":"regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity","type":"exact"},{"name":"regulation of cAMP-dependent protein kinase, intrinsic catalyst activity","type":"exact"},{"name":"regulation of cyclic AMP-dependent protein kinase activity","type":"exact"},{"name":"regulation of protein kinase A activity","type":"related"}],"termid":"GO:2000479"}


id: GO:0061547
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.","definition_xrefs":["PMID:21356517","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transferase activity, transferring phosphorus-containing groups","termid":"GO:0016772"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0003824","GO:0016740","GO:0003674"],"is_obsolete":false,"name":"glycogen synthase activity, transferring glucose-1-phosphate","secondary_identifiers":["Reactome:R-HSA-3780994","Reactome:R-HSA-3781024"],"termid":"GO:0061547"}


id: MONDO:0021222
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A neoplasm (disease) that involves the lacrimal gland.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"eye neoplasm","termid":"MONDO:0021220"},{"relation_name":"is_a","term_name":"disorder of lacrimal gland","termid":"MONDO:0024625"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"lacrimal gland neoplasm","secondary_identifiers":["NCIT:C4360","UMLS:C0339124","MEDGEN:83280"],"synonyms":[{"name":"lacrimal gland neoplasm (disease)","type":"exact"},{"name":"lacrimal gland tumor","type":"exact"},{"name":"lacrimal gland tumour","type":"exact"},{"name":"neoplasm of lacrimal gland","type":"exact"},{"name":"neoplasm of the lacrimal gland","type":"exact"},{"name":"tumor of lacrimal gland","type":"exact"},{"name":"tumor of the lacrimal gland","type":"exact"},{"name":"tumour of lacrimal gland","type":"exact"},{"name":"tumour of the lacrimal gland","type":"exact"}],"termid":"MONDO:0021222","xrefs":{"Monarch":{"xref_id":"0021222"}}}


id: GO:0035904
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.","definition_xrefs":["Wikipedia:Aorta","GOC:bf","GOC:dgh","MA:0000062","UBERON:0000947"],"direct_ancestors":[{"relation_name":"is_a","term_name":"artery development","termid":"GO:0060840"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"aorta development","termid":"GO:0035904"}


id: FYECO:0000060
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"Chemical was endogenously produced in the experiment.","definition_xrefs":["PomBase:al"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE FYECO:0000060 chemical produced (obsolete FYECO:0000060)","termid":"FYECO:0000060"}


id: PBO:0000535
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-dependent RNA helicase Rok1 (predicted)","termid":"PBO:0000535"}


id: GO:0055042
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate.","definition_xrefs":["GOC:jid","GOC:mlg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lactonohydrolase activity","termid":"GO:0046573"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016788","GO:0016787","GO:0003824","GO:0003674"],"is_obsolete":false,"name":"5-valerolactone hydrolase activity","termid":"GO:0055042"}


id: PBO:0111740
data:
  {"annotation_feature_type":"gene","cv_name":"pombase_family_or_domain","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RecQ family helicase","termid":"PBO:0111740"}


id: MONDO:0003244
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A benign or malignant mesenchymal neoplasm originating in the central nervous system or the meninges and showing fibrous, fibrohistiocytic, adipose, myoid, endothelial, chondroid or osseous, but not meningothelial differentiation. Depending on the histological features and clinical behavior of these neoplasms, their grade ranges from benign (WHO grade I) to highly malignant (WHO grade IV). (Adapted from WHO)","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"central nervous system cancer","termid":"MONDO:0002714"},{"relation_name":"is_a","term_name":"soft tissue neoplasm","termid":"MONDO:0006424"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"central nervous system mesenchymal non-meningothelial tumor","secondary_identifiers":["DOID:502","MEDGEN:234104","UMLS:C1332893","NCIT:C5449"],"synonyms":[{"name":"CNS soft tissue neoplasm","type":"exact"},{"name":"CNS soft tissue tumor","type":"exact"},{"name":"CNS soft tissue tumour","type":"exact"},{"name":"central nervous system mesenchymal, non-meningothelial neoplasm","type":"exact"},{"name":"central nervous system mesenchymal, non-meningothelial tumor","type":"exact"},{"name":"central nervous system mesenchymal, non-meningothelial tumour","type":"exact"},{"name":"central nervous system soft tissue neoplasm","type":"exact"},{"name":"central nervous system soft tissue tumor","type":"exact"},{"name":"central nervous system soft tissue tumour","type":"exact"},{"name":"mesenchymal non-meningothelial tumor of the central nervous system","type":"exact"},{"name":"mesenchymal non-meningothelial tumour of the central nervous system","type":"exact"},{"name":"mesenchymal, non-meningothelial tumor of CNS","type":"exact"},{"name":"mesenchymal, non-meningothelial tumor of central nervous system","type":"exact"},{"name":"mesenchymal, non-meningothelial tumor of the CNS","type":"exact"},{"name":"mesenchymal, non-meningothelial tumour of CNS","type":"exact"},{"name":"mesenchymal, non-meningothelial tumour of central nervous system","type":"exact"},{"name":"mesenchymal, non-meningothelial tumour of the CNS","type":"exact"},{"name":"non-meningothelial mesenchymal tumor","type":"exact"},{"name":"non-meningothelial mesenchymal tumour","type":"exact"},{"name":"soft tissue neoplasm of CNS","type":"exact"},{"name":"soft tissue neoplasm of central nervous system","type":"exact"},{"name":"soft tissue neoplasm of the CNS","type":"exact"},{"name":"soft tissue neoplasm of the central nervous system","type":"exact"},{"name":"soft tissue tumor of CNS","type":"exact"},{"name":"soft tissue tumor of central nervous system","type":"exact"},{"name":"soft tissue tumor of the CNS","type":"exact"},{"name":"soft tissue tumor of the central nervous system","type":"exact"},{"name":"soft tissue tumour of CNS","type":"exact"},{"name":"soft tissue tumour of central nervous system","type":"exact"},{"name":"soft tissue tumour of the CNS","type":"exact"},{"name":"soft tissue tumour of the central nervous system","type":"exact"}],"termid":"MONDO:0003244","xrefs":{"Monarch":{"xref_id":"0003244"}}}


id: MONDO:0012453
data:
  {"annotated_genes":["SJAG_05289"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87004],"is_not":false,"summary":null,"term":"MONDO:0012453"}]},"cv_name":"mondo","definition":"A rare type of hereditary spastic paraplegia usually characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood (>30 years). In some cases, it can present as a complex phenotype with additional associated manifestations including peripheral neuropathy, bulbar palsy (with dysarthria and dysphagia), distal amyotrophy, and impaired distal vibration sense.","definition_xrefs":["Orphanet:101011"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary spastic paraplegia","termid":"MONDO:0019064"}],"gene_count":1,"genes_by_uniquename":{"SJAG_05289":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0005559"],"is_obsolete":false,"name":"hereditary spastic paraplegia 31","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MESH:C565210","MEDGEN:377858","SCTID:763068005","OMIM:610250","DOID:0110782","GARD:10817","UMLS:C1853247"],"synonyms":[{"name":"REEP1 hereditary spastic paraplegia","type":"exact"},{"name":"SPG31","type":"exact"},{"name":"autosomal dominant spastic paraplegia 31","type":"exact"},{"name":"autosomal dominant spastic paraplegia type 31","type":"exact"},{"name":"hereditary spastic paraplegia caused by mutation in REEP1","type":"exact"},{"name":"hereditary spastic paraplegia type 31","type":"exact"},{"name":"spastic paraplegia 31","type":"related"},{"name":"spastic paraplegia 31, autosomal dominant","type":"related"}],"termid":"MONDO:0012453","terms_by_termid":{"MONDO:0012453":null},"xrefs":{"Monarch":{"xref_id":"0012453"}}}


id: PATO:0000675
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000675 body temperature value (obsolete PATO:0000675)","termid":"PATO:0000675"}


id: GO:0106299
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.","definition_xrefs":["PMID:28087575"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acute inflammatory response","termid":"GO:0002526"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"resolution phase response","termid":"GO:0106299"}


id: GO:0160040
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A migrasome-mediated selective removal of damaged mitochondria process that maintains mitochondrion homeostasis in migrating cells.","definition_xrefs":["PMID:34108688"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mitochondrion distribution","termid":"GO:0048311"},{"relation_name":"is_a","term_name":"establishment of mitochondrion localization","termid":"GO:0051654"},{"relation_name":"is_a","term_name":"migracytosis","termid":"GO:0140495"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006810","GO:0008150","GO:0051179"],"is_obsolete":false,"name":"mitocytosis","termid":"GO:0160040"}


id: MONDO:0008948
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cerebrotendinous xanthomatosis (CTX) is an anomaly of bile acid synthesis characterized by neonatal cholestasis, childhood-onset cataract, adolescent to young adult-onset tendon xanthomata, and brain xanthomata with adult-onset neurologic dysfunction.","definition_xrefs":["Orphanet:909"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xanthomatosis","termid":"MONDO:0002615"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"},{"relation_name":"is_a","term_name":"syndromic dyslipidemia","termid":"MONDO:0015905"},{"relation_name":"is_a","term_name":"leukodystrophy","termid":"MONDO:0019046"},{"relation_name":"is_a","term_name":"inborn disorder of bile acid synthesis","termid":"MONDO:0019218"},{"relation_name":"is_a","term_name":"subcutaneous tissue disorder","termid":"MONDO:0019296"},{"relation_name":"is_a","term_name":"autosomal recessive metabolic cerebellar ataxia","termid":"MONDO:0020044"},{"relation_name":"is_a","term_name":"hereditary peripheral neuropathy","termid":"MONDO:0020127"},{"relation_name":"is_a","term_name":"cerebral lipidosis with dementia","termid":"MONDO:0020143"},{"relation_name":"is_a","term_name":"cholesterol catabolic process disease","termid":"MONDO:0045016"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0002561"},{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0002525"},{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0005559"},{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005244"}],"interesting_parent_ids":["MONDO:0002525","MONDO:0005066","MONDO:0002039","MONDO:0002561","MONDO:0005559","MONDO:0005328","MONDO:0005244","MONDO:0006025"],"is_obsolete":false,"name":"cerebrotendinous xanthomatosis","secondary_identifiers":["DOID:4810","OMIM:213700","GARD:5622","MESH:D019294","NANDO:1200856","MEDGEN:116041","icd11.foundation:1556875179","NCIT:C84628","SCTID:63246000","UMLS:C0238052"],"synonyms":[{"name":"CTX","type":"exact"},{"name":"CTx","type":"exact"},{"name":"cerebral cholesterinosis","type":"related"},{"name":"cerebrotendinous xanthomatosis","type":"exact"},{"name":"cholestanol storage disease","type":"exact"},{"name":"sterol 27-hydroxylase deficiency","type":"exact"}],"termid":"MONDO:0008948","xrefs":{"Monarch":{"xref_id":"0008948"}}}


id: GO:0047731
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.","definition_xrefs":["EC:1.1.3.14","MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor","termid":"GO:0016899"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"catechol oxidase (dimerizing) activity","secondary_identifiers":["RHEA:12809"],"synonyms":[{"name":"catechol:oxygen oxidoreductase (dimerizing)","type":"related"}],"termid":"GO:0047731"}


id: GO:0043403
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.","definition_xrefs":["GOC:mtg_muscle","PMID:16607119","PMID:12021255","GOC:ef"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tissue regeneration","termid":"GO:0042246"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"skeletal muscle tissue regeneration","synonyms":[{"name":"myofiber turnover","type":"related"}],"termid":"GO:0043403"}


id: PBO:0059177
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"muscle RAS oncogene homolog","termid":"PBO:0059177"}


id: MOD:00447
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively results from forming an adduct with a glucuronic acid either through a carboxyl group amide or ester bond, or through C1-glycosylation.","definition_xrefs":["DeltaMass:0","PubMed:7398618","Unimod:54#N-term"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycoconjugated residue","termid":"MOD:00764"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"N-glucuronylated residue","synonyms":[{"name":"Glucuronyl","type":"related"},{"name":"N-Glucuronyl (N terminus)","type":"exact"},{"name":"N-glucuronylation","type":"related"}],"termid":"MOD:00447"}


id: MONDO:0002085
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"movement disorder","termid":"MONDO:0005395"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign shuddering attacks","secondary_identifiers":["ICD10CM:G25.83","UMLS:C0375200","DOID:1713","ICD9:333.93","SCTID:446995005","MEDGEN:580931"],"termid":"MONDO:0002085","xrefs":{"Monarch":{"xref_id":"0002085"}}}


id: GO:0016298
data:
  {"annotated_genes":["SJAG_03204","SJAG_02091","SJAG_04973","SJAG_04105","SJAG_03604","SJAG_02907","SJAG_00321","SJAG_02487","SJAG_02093","SJAG_02543","SJAG_00199","SJAG_01198","SJAG_01519","SJAG_02068","SJAG_00158","SJAG_04790","SJAG_02100","SJAG_02161","SJAG_01219","SJAG_02715","SJAG_04323","SJAG_04292","SJAG_01036","SJAG_02089","SJAG_04110"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[100692],"is_not":false,"summary":null,"term":"GO:0016298"},{"annotations":[72489,95766,116038,65928,67316,68970],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004622"},{"annotations":[110769],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052714"},{"annotations":[80246,79072,80545,72635],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0047372"},{"annotations":[99645],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034479"},{"annotations":[74500],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004435"},{"annotations":[80343,78188,79169,72839],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004623"},{"annotations":[79853,77636],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004620"},{"annotations":[76107],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004630"},{"annotations":[63991],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004767"},{"annotations":[76908,79177,76757],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004771"},{"annotations":[71489,58459,73228,95767,100342,60211],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0004806"}]},"cv_name":"molecular_function","definition":"Catalysis of the hydrolysis of a lipid.","definition_xrefs":["ISBN:0198506732","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on ester bonds","termid":"GO:0016788"}],"gene_count":25,"genes_by_uniquename":{"SJAG_00158":null,"SJAG_00199":null,"SJAG_00321":null,"SJAG_01036":null,"SJAG_01198":null,"SJAG_01219":null,"SJAG_01519":null,"SJAG_02068":null,"SJAG_02089":null,"SJAG_02091":null,"SJAG_02093":null,"SJAG_02100":null,"SJAG_02161":null,"SJAG_02487":null,"SJAG_02543":null,"SJAG_02715":null,"SJAG_02907":null,"SJAG_03204":null,"SJAG_03604":null,"SJAG_04105":null,"SJAG_04110":null,"SJAG_04292":null,"SJAG_04323":null,"SJAG_04790":null,"SJAG_04973":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016788","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"lipase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000003":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-163402","Reactome:R-HSA-163432"],"termid":"GO:0016298","terms_by_termid":{"GO:0004435":null,"GO:0004620":null,"GO:0004622":null,"GO:0004623":null,"GO:0004630":null,"GO:0004767":null,"GO:0004771":null,"GO:0004806":null,"GO:0016298":null,"GO:0034479":null,"GO:0047372":null,"GO:0052714":null}}


id: PBO:0116636
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ARF GTPase activating protein 2","termid":"PBO:0116636"}


id: PBO:0045715
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"E2F transcription factor 3","termid":"PBO:0045715"}


id: MONDO:1010953
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Schwannomatosis that occurs in cattle.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"bovine neoplasm","termid":"MONDO:0700134"},{"relation_name":"is_a","term_name":"schwannomatosis, non-human animal","termid":"MONDO:1010217"},{"relation_name":"is_a","term_name":"neurofibromatosis, cattle","termid":"MONDO:1011566"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"schwannomatosis, cattle","secondary_identifiers":["OMIA:001963-9913"],"termid":"MONDO:1010953","xrefs":{"Monarch":{"xref_id":"1010953"}}}


id: PATO:0001399
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A cellular potency that is the capacity to produce differentiated cell types of all three primary germ layers and extraembryonic cell types.","definition_xrefs":["Wikipedia:http://en.wikipedia.org/wiki/Totipotent"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cellular potency","termid":"PATO:0001397"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"totipotent","termid":"PATO:0001399"}


id: PR:Q9UTE2
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO00382","PRO:DNx","PANTHER:PTHR10755:SF0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"oxygen-dependent coproporphyrinogen-III oxidase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC222.11","secondary_identifiers":["UniProtKB:Q9UTE2"],"synonyms":[{"name":"COX (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Coproporphyrinogenase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-CPOX","type":"exact"},{"name":"coprogen oxidase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9UTE2"}


id: FYPO:0004578
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured in the cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein level during vegetative growth","termid":"FYPO:0001324"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0006551","FYPO:0000002","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"decreased level of histone H3 in cell","synonyms":[{"name":"decreased accumulation of histone H3 in cell","type":"related"},{"name":"decreased cellular histone H3 level","type":"exact"},{"name":"decreased histone H3 level during vegetative growth","type":"exact"},{"name":"decreased level of histone H3 in cell during mitotic cell cycle","type":"related"},{"name":"decreased level of histone H3 in cell during vegetative growth","type":"exact"},{"name":"reduced level of histone H3 in cell","type":"exact"}],"termid":"FYPO:0004578"}


id: PBO:0064454
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pogo transposable element derived with KRAB domain","termid":"PBO:0064454"}


id: PBO:0035789
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_replication_fork_pausing_at_highly_transcribed_RNA_polymerase_II_genes","termid":"PBO:0035789"}


id: PBO:0062076
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 4 subfamily A member 7 pseudogene","termid":"PBO:0062076"}


id: PBO:0117043
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MAX antisense RNA 1","termid":"PBO:0117043"}


id: GO:0004506
data:
  {"annotated_genes":["SJAG_00370"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[78997],"is_not":false,"summary":null,"term":"GO:0004506"}]},"cv_name":"molecular_function","definition":"Catalysis of the reaction: H+ + NADPH + O2 + squalene = (S)-2,3-epoxysqualene + H2O + NADP+.","definition_xrefs":["RHEA:25282"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","termid":"GO:0016709"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00370":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"squalene monooxygenase activity","references_by_uniquename":{"GO_REF:0000033":null},"secondary_identifiers":["Reactome:R-HSA-191299","MetaCyc:SQUALENE-MONOOXYGENASE-RXN","KEGG_REACTION:R02874","EC:1.14.14.17"],"synonyms":[{"name":"squalene 2,3-oxidocyclase activity","type":"related"},{"name":"squalene epoxidase activity","type":"related"},{"name":"squalene hydroxylase activity","type":"related"},{"name":"squalene oxydocyclase activity","type":"related"},{"name":"squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity","type":"exact"},{"name":"squalene-2,3-epoxidase activity","type":"related"},{"name":"squalene-2,3-epoxide cyclase activity","type":"related"}],"termid":"GO:0004506","terms_by_termid":{"GO:0004506":null}}


id: PBO:0034098
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-realized_in","termid":"PBO:0034098"}


id: PBO:0067919
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 221","termid":"PBO:0067919"}


id: FYPO:0001930
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to gamma radiation is abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cellular response to stress during vegetative growth","termid":"FYPO:0001341"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000298","FYPO:0000002","FYPO:0001985","FYPO:0005447"],"is_obsolete":false,"name":"abnormal cellular response to gamma radiation","synonyms":[{"name":"abnormal cellular response to gamma radiation during mitotic cell cycle","type":"related"},{"name":"abnormal cellular response to gamma radiation during vegetative growth","type":"exact"},{"name":"abnormal sensitivity to gamma radiation","type":"exact"}],"termid":"FYPO:0001930"}


id: GO:0050677
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