# terms

id: MONDO:0015573
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Subacute cutaneous lupus erythematosus (SCLE) is a form of cutaneous lupus erythematosus (CLE) that can present either as a non-scarring, annular photo-distributed dermatosis or psoriasiform plaques. SCLE is associated with anti-Ro/SSA antibodies and can be drug-induced.","definition_xrefs":["Orphanet:163525"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cutaneous lupus erythematosus","termid":"MONDO:0005282"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"subacute cutaneous lupus erythematosus","secondary_identifiers":["GARD:20042","MedDRA:10057903","SCTID:239891002","icd11.foundation:192274757","ICD10CM:L93.1","UMLS:C0024140","NCIT:C117111","MEDGEN:7403"],"termid":"MONDO:0015573","xrefs":{"Monarch":{"xref_id":"0015573"}}}


id: GO:0050760
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of thymidylate synthase biosynthetic process (obsolete GO:0050760)","synonyms":[{"name":"down regulation of thymidylate synthase biosynthetic process","type":"exact"},{"name":"down-regulation of thymidylate synthase biosynthetic process","type":"exact"},{"name":"downregulation of thymidylate synthase biosynthetic process","type":"exact"},{"name":"inhibition of thymidylate synthase biosynthetic process","type":"narrow"},{"name":"negative regulation of thymidylate synthase anabolism","type":"exact"},{"name":"negative regulation of thymidylate synthase biosynthesis","type":"exact"},{"name":"negative regulation of thymidylate synthase formation","type":"exact"},{"name":"negative regulation of thymidylate synthase synthesis","type":"exact"}],"termid":"GO:0050760"}


id: MONDO:0016662
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare autoinflammatory syndrome defined as recurrence of pericardial inflammation of unknown origin following the first episode of acute pericarditis and a symptom-free interval of 4-6 weeks or longer. Recurrent attacks of chest pain may be the sole presentation or the chest pain may be accompanied by pericardial friction rub, electrocardiographic or echocardiographic changes, pericardial effusion and increased C-reactive protein. Cardiac tamponade is a rare, life-threatening complication.","definition_xrefs":["Orphanet:251307"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autoinflammatory syndrome","termid":"MONDO:0019751"},{"relation_name":"is_a","term_name":"idiopathic disease","termid":"MONDO:0700007"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"idiopathic recurrent pericarditis","secondary_identifiers":["GARD:20695","SCTID:766704005","ICD10CM:I09.2","UMLS:C4707790","MEDGEN:1642945"],"synonyms":[{"name":"idiopathic relapsing pericarditis","type":"exact"}],"termid":"MONDO:0016662","xrefs":{"Monarch":{"xref_id":"0016662"}}}


id: GO:1905611
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding.","definition_xrefs":["PMID:23409027","GOC:PARL","GO_REF:0000059","GOC:TermGenie","GOC:bc"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of mRNA cap binding (obsolete GO:1905611)","synonyms":[{"name":"down regulation of mRNA cap binding","type":"exact"},{"name":"down-regulation of mRNA cap binding","type":"exact"},{"name":"downregulation of mRNA cap binding","type":"exact"},{"name":"inhibition of mRNA cap binding","type":"narrow"}],"termid":"GO:1905611"}


id: PBO:0060844
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurofilament medium pseudogene 1","termid":"PBO:0060844"}


id: GO:0150016
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma).","definition_xrefs":["GOC:bc","GOC:aruk","PMID:17046728","PMID:9214543","PMID:1720142","PMID:20629984","PMID:22683681"],"direct_ancestors":[{"relation_name":"is_a","term_name":"basal dendrite","termid":"GO:0097441"},{"relation_name":"is_a","term_name":"distal dendrite","termid":"GO:0150002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"basal distal dendrite","termid":"GO:0150016"}


id: PBO:0016112
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA pseudouridine synthase Pus3 (predicted)","termid":"PBO:0016112"}


id: GO:0015232
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transfer of heme from one side of a membrane to the other.","definition_xrefs":["PMID:29549126"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transmembrane transporter activity","termid":"GO:0022857"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0022857","GO:0003674"],"is_obsolete":false,"name":"heme transmembrane transporter activity","secondary_identifiers":["Reactome:R-HSA-917870","Reactome:R-HSA-917892","Reactome:R-HSA-9661408"],"synonyms":[{"name":"haem transporter activity","type":"exact"},{"name":"heme transporter activity","type":"broad"}],"termid":"GO:0015232"}


id: MONDO:0013772
data:
  {"annotated_genes":["SJAG_04325"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88507],"is_not":false,"summary":null,"term":"MONDO:0013772"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04325":null},"genotype_count":0,"is_obsolete":false,"name":"Huppke-Brendel syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["Orphanet:300313","UMLS:C4751114","MEDGEN:1659966","GARD:17365","OMIM:614482"],"synonyms":[{"name":"CCHLND","type":"related"},{"name":"Huppke-Brendel syndrome","type":"exact"},{"name":"acetyl CoA transporter deficiency","type":"exact"},{"name":"congenital cataract-deafness-severe developmental delay syndrome","type":"exact"},{"name":"congenital cataracts, hearing loss, and neurodegeneration","type":"exact"},{"name":"lethal neurodegenerative disorder due to copper transport defect","type":"exact"}],"termid":"MONDO:0013772","terms_by_termid":{"MONDO:0013772":null},"xrefs":{"Monarch":{"xref_id":"0013772"}}}


id: GO:0019309
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mannose metabolic process","termid":"GO:0006013"},{"relation_name":"is_a","term_name":"hexose catabolic process","termid":"GO:0019320"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0005975"],"is_obsolete":false,"name":"mannose catabolic process","synonyms":[{"name":"mannose breakdown","type":"exact"},{"name":"mannose catabolism","type":"exact"},{"name":"mannose degradation","type":"exact"}],"termid":"GO:0019309"}


id: PBO:0055395
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 2825","termid":"PBO:0055395"}


id: PBO:0030199
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-resistance_to_cytochalasin_B","termid":"PBO:0030199"}


id: PBO:0061226
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"NODAL modulator 2","termid":"PBO:0061226"}


id: PBO:0049252
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"growth hormone regulated TBC protein 1","termid":"PBO:0049252"}


id: PBO:0016103
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HEAT repeat protein, involved in protein localization to plasma membrane (predicted)","termid":"PBO:0016103"}


id: MONDO:0010712
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"panhypopituitarism","termid":"MONDO:0019591"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"panhypopituitarism, X-linked","secondary_identifiers":["UMLS:C0342376","SCTID:237683004","MEDGEN:87439","MESH:C538613","DOID:0111779","GARD:6737","OMIM:312000"],"synonyms":[{"name":"PHPX","type":"related"},{"name":"panhypopituitarism X-linked","type":"related"},{"name":"panhypopituitarism, X-linked","type":"exact"},{"name":"pituitary dwarfism IV","type":"related"},{"name":"pituitary dwarfism IV (formerly)","type":"related"},{"name":"pituitary dwarfism IV, formerly","type":"related"}],"termid":"MONDO:0010712","xrefs":{"Monarch":{"xref_id":"0010712"}}}


id: PBO:0003487
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"1.13.11.-","termid":"PBO:0003487"}


id: PBO:0082975
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytoplasmic thioredoxin isoenzyme; part of the thioredoxin system that protects cells from oxidative and reductive stress; subunit of the LMA1 complex, with Pbi2p, that promotes vacuole inheritance; cofactor for Tsa1p; required for ER-Golgi transport; facilitates mitochondrial import of small Tims (Tim9p, Tim10p, Tim13p) by maintaining them in reduced form along with Trx1p; component of a signal transduction redox relay in a light sensing pathway; abundance increases under DNA replication stress","termid":"PBO:0082975"}


id: MONDO:0012590
data:
  {"annotated_genes":["SJAG_02556"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88343],"is_not":false,"summary":null,"term":"MONDO:0012590"}]},"cv_name":"mondo","definition":"A syndrome characterized by aged bird-like facies, lack of subcutaneous fat, dwarfism, cachexia and microcephaly. Additional features include sun-sensitivity from birth, learning disabilities, hearing loss, and visual impairment. It has material basis in homozygous mutation in the ERCC4 gene on chromosome 16p13.","definition_xrefs":["DOID:0060590","PMID:17183314"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02556":null},"genotype_count":0,"is_obsolete":false,"name":"XFE progeroid syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:610965","NCIT:C173111","UMLS:C1970416","MEDGEN:410064","MESH:C567043"],"synonyms":[{"name":"XFE progeroid syndrome","type":"exact"},{"name":"XFEPS","type":"exact"},{"name":"XPF-ERCC1 progeroid syndrome","type":"exact"}],"termid":"MONDO:0012590","terms_by_termid":{"MONDO:0012590":null},"xrefs":{"Monarch":{"xref_id":"0012590"}}}


id: GO:0070237
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.","definition_xrefs":["GOC:add","ISBN:0781765196"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of immune system process","termid":"GO:0002684"},{"relation_name":"is_a","term_name":"positive regulation of T cell apoptotic process","termid":"GO:0070234"},{"relation_name":"is_a","term_name":"regulation of activation-induced cell death of T cells","termid":"GO:0070235"},{"relation_name":"positively_regulates","term_name":"activation-induced cell death of T cells","termid":"GO:0006924"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of activation-induced cell death of T cells","synonyms":[{"name":"activation of activation-induced cell death of T cells","type":"narrow"},{"name":"positive regulation of AICD","type":"broad"},{"name":"positive regulation of activated T cell apoptosis","type":"broad"},{"name":"positive regulation of activation-induced cell death of T lymphocytes","type":"exact"},{"name":"positive regulation of activation-induced cell death of T-cells","type":"exact"},{"name":"positive regulation of activation-induced cell death of T-lymphocytes","type":"exact"},{"name":"positive regulation of antigen-driven apoptosis","type":"broad"},{"name":"stimulation of activation-induced cell death of T cells","type":"narrow"},{"name":"up regulation of activation-induced cell death of T cells","type":"exact"},{"name":"up-regulation of activation-induced cell death of T cells","type":"exact"},{"name":"upregulation of activation-induced cell death of T cells","type":"exact"}],"termid":"GO:0070237"}


id: PBO:0062288
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily L member 1","termid":"PBO:0062288"}


id: PBO:0047398
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"F-box protein 36 pseudogene 1","termid":"PBO:0047398"}


id: PBO:0091807
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by S. japonicus rsv1","termid":"PBO:0091807"}


id: PBO:0074869
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nucleolar RNA, C/D box 53","termid":"PBO:0074869"}


id: GO:0102188
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ = 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity (obsolete GO:0102188)","termid":"GO:0102188"}


id: MONDO:0001488
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"corneal deposit","termid":"MONDO:0001308"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"anterior corneal pigmentation","secondary_identifiers":["ICD9:371.11","UMLS:C0155104","MEDGEN:509790","DOID:12307","SCTID:18377001"],"synonyms":[{"name":"anterior corneal pigmentations","type":"exact"}],"termid":"MONDO:0001488","xrefs":{"Monarch":{"xref_id":"0001488"}}}


id: FYPO_EXT:0000003
data:
  {"annotation_feature_type":"gene","cv_name":"fypo_extensions","definition":"small fraction of cells (penetrance) or weak phenotype (severity)","definition_xrefs":["PomBase:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"FYPO severity extension","termid":"FYPO_EXT:1000001"},{"relation_name":"is_a","term_name":"FYPO penetrance extension","termid":"FYPO_EXT:1000002"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"low","termid":"FYPO_EXT:0000003"}


id: SO:0002367
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A gene that codes for plastid LSU rRNA.","direct_ancestors":[{"relation_name":"is_a","term_name":"plastid_rRNA_gene","termid":"SO:0002366"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plastid_LSU_rRNA_gene","synonyms":[{"name":"plastid large subunit rRNA gene","type":"exact"}],"termid":"SO:0002367"}


id: MONDO:0000358
data:
  {"annotated_genes":["SJAG_03843"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88886],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0013378"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"disorder of facial skeleton","termid":"MONDO:0023369"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03843":null},"genotype_count":0,"is_obsolete":false,"name":"orofacial cleft","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:472000","UMLS:C3266076","SCTID:449790007","DOID:0050567","OMIMPS:119530"],"termid":"MONDO:0000358","terms_by_termid":{"MONDO:0013378":null},"xrefs":{"Monarch":{"xref_id":"0000358"}}}


id: PBO:0089646
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ras GEF Ste6","termid":"PBO:0089646"}


id: MONDO:0005225
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete acute myeloblastic leukemia with maturation (obsolete MONDO:0005225)","termid":"MONDO:0005225","xrefs":{"Monarch":{"xref_id":"0005225"}}}


id: MONDO:0009500
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"kuru","termid":"MONDO:0006825"},{"relation_name":"is_a","term_name":"inherited disease susceptibility","termid":"MONDO:0020573"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kuru, susceptibility to","secondary_identifiers":["UMLS:C1855588","MEDGEN:343389","OMIM:245300"],"synonyms":[{"name":"kuru, susceptibility to","type":"exact"},{"name":"susceptibility to kuru","type":"related"}],"termid":"MONDO:0009500","xrefs":{"Monarch":{"xref_id":"0009500"}}}


id: PBO:0034558
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histone_H2B-K119_ubiquitination","termid":"PBO:0034558"}


id: GO:0004507
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.","definition_xrefs":["EC:1.14.15.4"],"direct_ancestors":[{"relation_name":"is_a","term_name":"steroid hydroxylase activity","termid":"GO:0008395"},{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen","termid":"GO:0016713"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"steroid 11-beta-monooxygenase activity","secondary_identifiers":["Reactome:R-HSA-194017","RHEA:15629","MetaCyc:STEROID-11-BETA-MONOOXYGENASE-RXN","Reactome:R-HSA-193997","Reactome:R-HSA-5580292","Reactome:R-HSA-5600598"],"synonyms":[{"name":"cytochrome P450 CYP11B1","type":"narrow"},{"name":"cytochrome P450 CYP11B2","type":"narrow"},{"name":"cytochrome p450 XIB1 activity","type":"narrow"},{"name":"oxygenase, steroid 11beta -mono-","type":"related"},{"name":"steroid 11-beta-hydroxylase activity","type":"exact"},{"name":"steroid 11-beta/18-hydroxylase activity","type":"related"},{"name":"steroid 11beta-hydroxylase activity","type":"related"},{"name":"steroid 11beta-monooxygenase activity","type":"related"},{"name":"steroid 11beta/18-hydroxylase activity","type":"related"},{"name":"steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)","type":"related"}],"termid":"GO:0004507"}


id: PR:P40976
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- lys1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:P40976"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-2-aminoadipate reductase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAP7G5.04c","synonyms":[{"name":"L-aminoadipate-semialdehyde dehydrogenase (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-lys1","type":"exact"},{"name":"alpha-AR (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"alpha-aminoadipate reductase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P40976"}


id: MONDO:0018002
data:
  {"annotated_genes":["SJAG_06022"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[86958],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0014656"}]},"cv_name":"mondo","definition":"Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy is a rare mitochondrial disease characterized by adult onset of progressive external ophthalmoplegia, exercise intolerance, muscle weakness, manifestations of spinocerebellar ataxia (e.g. impaired gait, dysarthria) and mild motor peripheral neuropathy. Respiratory insufficiency has been reported in some cases.","definition_xrefs":["Orphanet:329336"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn mitochondrial myopathy","termid":"MONDO:0009637"},{"relation_name":"is_a","term_name":"mitochondrial oxidative phosphorylation disorder","termid":"MONDO:0016387"}],"gene_count":1,"genes_by_uniquename":{"SJAG_06022":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004069"},{"rel_name":"is_a","termid":"MONDO:0005336"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0004069","MONDO:0005336"],"is_obsolete":false,"name":"adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:17503","MEDGEN:1393682","SCTID:725464001","UMLS:C4511138"],"synonyms":[{"name":"adult-onset CPEO with mitochondrial myopathy","type":"exact"}],"termid":"MONDO:0018002","terms_by_termid":{"MONDO:0014656":null},"xrefs":{"Monarch":{"xref_id":"0018002"}}}


id: GO:0002906
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.","definition_xrefs":["GOC:add","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of B cell apoptotic process","termid":"GO:0002903"},{"relation_name":"is_a","term_name":"regulation of mature B cell apoptotic process","termid":"GO:0002905"},{"relation_name":"negatively_regulates","term_name":"mature B cell apoptotic process","termid":"GO:0002901"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of mature B cell apoptotic process","synonyms":[{"name":"down regulation of mature B cell apoptosis","type":"exact"},{"name":"down-regulation of mature B cell apoptosis","type":"exact"},{"name":"downregulation of mature B cell apoptosis","type":"exact"},{"name":"inhibition of mature B cell apoptosis","type":"narrow"},{"name":"negative regulation of mature B cell apoptosis","type":"narrow"}],"termid":"GO:0002906"}


id: PBO:0047903
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"fragile site, aphidicolin type, common, fra(7)(q11)","termid":"PBO:0047903"}


id: GO:0048774
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.","definition_xrefs":["GOC:jid","GOC:mh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"pigment cell differentiation","termid":"GO:0050931"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cyanophore differentiation","synonyms":[{"name":"cyanophore cell differentiation","type":"exact"}],"termid":"GO:0048774"}


id: GO:0140035
data:
  {"annotated_genes":["SJAG_04574"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[112496],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061649"}]},"cv_name":"molecular_function","definition":"A molecular adaptor that recognizes and binds a target protein containing a ubiquitin-like modification and that brings the target protein into contact with another protein to allow those proteins to function in a coordinated way.","definition_xrefs":["PMID:26060076"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-macromolecule adaptor activity","termid":"GO:0030674"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04574":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0030674"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0060090"}],"interesting_parent_ids":["GO:0003674","GO:0030674","GO:0060090"],"is_obsolete":false,"name":"ubiquitin-like protein reader activity","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"ubiquitination-like modification-dependent protein binding","type":"exact"},{"name":"ubiquitination-like protein reader activity","type":"exact"}],"termid":"GO:0140035","terms_by_termid":{"GO:0061649":null}}


id: FYPO:0006032
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased during mitotic DNA replication.","definition_xrefs":["PMID:28481910","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein localization to chromatin during vegetative growth","termid":"FYPO:0002909"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0001985","FYPO:0005447","FYPO:0000002","FYPO:0001320"],"is_obsolete":false,"name":"decreased protein localization to chromatin during mitotic DNA replication","synonyms":[{"name":"decreased protein localisation to chromatin during mitotic DNA replication","type":"exact"},{"name":"decreased protein localization to chromatin during DNA replication during mitotic cell cycle","type":"related"},{"name":"decreased protein localization to chromatin during DNA replication during vegetative growth","type":"exact"},{"name":"reduced protein localization to chromatin during mitotic DNA replication","type":"exact"}],"termid":"FYPO:0006032"}


id: PBO:0017808
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vitamin H transmembrane transporter (predicted)","termid":"PBO:0017808"}


id: PBO:0004882
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial inner membrane protein involved in cytochrome c oxidase assembly Pet191 (predicted)","termid":"PBO:0004882"}


id: SO:1001186
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:1001186 sequence_variant_causing_cryptic_splice_acceptor_activation (obsolete SO:1001186)","synonyms":[{"name":"sequence variant causing cryptic splice acceptor activation","type":"exact"}],"termid":"SO:1001186"}


id: GO:0045992
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of embryonic development","termid":"GO:0045995"},{"relation_name":"is_a","term_name":"negative regulation of developmental process","termid":"GO:0051093"},{"relation_name":"is_a","term_name":"negative regulation of multicellular organismal process","termid":"GO:0051241"},{"relation_name":"negatively_regulates","term_name":"embryo development","termid":"GO:0009790"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"negative regulation of embryonic development","synonyms":[{"name":"down regulation of embryonic development","type":"exact"},{"name":"down-regulation of embryonic development","type":"exact"},{"name":"downregulation of embryonic development","type":"exact"},{"name":"inhibition of embryonic development","type":"narrow"}],"termid":"GO:0045992"}


id: PBO:0091359
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dpb4-interacting, RRM and IDR-containing factor","termid":"PBO:0091359"}


id: MONDO:0007494
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete episodic kinesigenic dyskinesia 1 (obsolete MONDO:0007494)","secondary_identifiers":["NANDO:1200521"],"termid":"MONDO:0007494","xrefs":{"Monarch":{"xref_id":"0007494"}}}


id: PBO:0036338
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"metal-dependent protein hydrolase family protein, human C12orf10 ortholog","termid":"PBO:0036338"}


id: GO:0035648
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.","definition_xrefs":["PMID:17276917","GOC:bf","GOC:dos","PMID:11470898"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mating behavior","termid":"GO:0007617"},{"relation_name":"is_a","term_name":"circadian behavior","termid":"GO:0048512"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"circadian mating behavior","synonyms":[{"name":"circadian mating behaviour","type":"exact"},{"name":"circadian mating rhythm","type":"exact"}],"termid":"GO:0035648"}


id: GO:1990957
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.","definition_xrefs":["PMID:18337471","PMID:21498478","PMID:25150219","GOC:cilia","PMID:21422230","PMID:21555462"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex","termid":"GO:0032991"},{"relation_name":"part_of","term_name":"ciliary transition zone","termid":"GO:0035869"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0032991"],"is_obsolete":false,"name":"NPHP complex","synonyms":[{"name":"NPHP module","type":"exact"}],"termid":"GO:1990957"}


id: PR:Q9UTK6
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A tuftelin-interacting protein 11 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR23329:SF1","OMA:SCHPO01334","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G-patch domain-containing protein C1486.03 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC1486.03c","secondary_identifiers":["UniProtKB:Q9UTK6"],"synonyms":[{"name":"Spom972h-TFIP11","type":"exact"}],"termid":"PR:Q9UTK6"}


id: GO:0042850
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.","definition_xrefs":["GOC:mah","GOC:jsg","ISBN:0198506732"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-sorbose metabolic process","termid":"GO:0019312"},{"relation_name":"is_a","term_name":"hexose catabolic process","termid":"GO:0019320"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"L-sorbose catabolic process","synonyms":[{"name":"L-sorbose breakdown","type":"exact"},{"name":"L-sorbose catabolism","type":"exact"},{"name":"L-sorbose degradation","type":"exact"}],"termid":"GO:0042850"}


id: GO:0035036
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.","definition_xrefs":["GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell recognition","termid":"GO:0009988"},{"relation_name":"part_of","term_name":"single fertilization","termid":"GO:0007338"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"sperm-egg recognition","secondary_identifiers":["Reactome:R-HSA-1300642","Reactome:R-HSA-2534343"],"termid":"GO:0035036"}


id: GO:0008829
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: dCTP + H2O = dUTP + NH3.","definition_xrefs":["EC:3.5.4.13"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines","termid":"GO:0016814"},{"relation_name":"is_a","term_name":"deaminase activity","termid":"GO:0019239"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016810"}],"interesting_parent_ids":["GO:0016810","GO:0003824","GO:0003674","GO:0016787"],"is_obsolete":false,"name":"dCTP deaminase activity","secondary_identifiers":["MetaCyc:DCTP-DEAM-RXN","RHEA:22680","Reactome:R-HSA-180632"],"synonyms":[{"name":"5-methyl-dCTP deaminase activity","type":"related"},{"name":"dCTP aminohydrolase activity","type":"related"},{"name":"deoxycytidine triphosphate deaminase activity","type":"related"}],"termid":"GO:0008829"}


id: PBO:0080417
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"VPS51 pseudogene 1","termid":"PBO:0080417"}


id: GO:0099109
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel.","definition_xrefs":["PMID:9429760","GOC:dos"],"gene_count":0,"genotype_count":0,"name":"obsolete potassium channel activating, G protein-coupled receptor signaling pathway (obsolete GO:0099109)","synonyms":[{"name":"potassium channel activating, G-protein coupled receptor signaling pathway","type":"exact"}],"termid":"GO:0099109"}


id: PBO:0087240
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Serine kinase involved in cell cycle regulation and rDNA integrity; associated with late pre-40S particles via its conserved C-terminal domain; prevents premature use of pre-40S particles in translation; association with pre-40S particles regulated by its catalytic ATPase site and likely occurs after the release of Rio2p from these particles; involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA; phosphorylates Rpa43p in anaphase to remove Pol I from rDNA","termid":"PBO:0087240"}


id: MONDO:0011784
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any Moyamoya disease in which the cause of the disease is a mutation in the RNF213 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Moyamoya disease","termid":"MONDO:0016820"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Moyamoya disease 2","secondary_identifiers":["MESH:C536992","NCIT:C183312","OMIM:607151","UMLS:C1846689","MEDGEN:339584","GARD:15410"],"synonyms":[{"name":"MYMY2","type":"related"},{"name":"Moyamoya disease 2","type":"exact"},{"name":"Moyamoya disease caused by mutation in RNF213","type":"exact"},{"name":"Moyamoya disease type 2","type":"exact"},{"name":"RNF213 Moyamoya disease","type":"exact"},{"name":"moyamoya disease 2, susceptibility to","type":"exact"}],"termid":"MONDO:0011784","xrefs":{"Monarch":{"xref_id":"0011784"}}}


id: GO:0009307
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.","definition_xrefs":["GOC:jl","UniProtKB-KW:KW-0680"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DNA modification","termid":"GO:0006304"},{"relation_name":"is_a","term_name":"clearance of foreign intracellular DNA","termid":"GO:0044355"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006259"}],"interesting_parent_ids":["GO:0008150","GO:0006259"],"is_obsolete":false,"name":"DNA restriction-modification system","synonyms":[{"name":"DNA restriction","type":"broad"}],"termid":"GO:0009307"}


id: MONDO:0800435
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovarian cancer, familial, susceptibility to, 3","secondary_identifiers":["UMLS:C3150661","MEDGEN:462011"],"termid":"MONDO:0800435","xrefs":{"Monarch":{"xref_id":"0800435"}}}


id: PBO:0054125
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1491","termid":"PBO:0054125"}


id: GO:1903485
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.","definition_xrefs":["GOC:TermGenie","GO_REF:0000058","GOC:mtg_cell_cycle"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of maintenance of mitotic actomyosin contractile ring localization (obsolete GO:1903485)","synonyms":[{"name":"activation of cytokinetic ring anchoring involved in mitotic cell cycle","type":"related"},{"name":"activation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"narrow"},{"name":"activation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"narrow"},{"name":"activation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle","type":"related"},{"name":"activation of maintenance of mitotic actomyosin contractile ring localization","type":"narrow"},{"name":"positive regulation of cytokinetic ring anchoring involved in mitotic cell cycle","type":"related"},{"name":"positive regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"positive regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"positive regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle","type":"related"},{"name":"up regulation of cytokinetic ring anchoring involved in mitotic cell cycle","type":"related"},{"name":"up regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"up regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"up regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle","type":"related"},{"name":"up regulation of maintenance of mitotic actomyosin contractile ring localization","type":"exact"},{"name":"up-regulation of cytokinetic ring anchoring involved in mitotic cell cycle","type":"related"},{"name":"up-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"up-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"up-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle","type":"related"},{"name":"up-regulation of maintenance of mitotic actomyosin contractile ring localization","type":"exact"},{"name":"upregulation of cytokinetic ring anchoring involved in mitotic cell cycle","type":"related"},{"name":"upregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"upregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle","type":"exact"},{"name":"upregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle","type":"related"},{"name":"upregulation of maintenance of mitotic actomyosin contractile ring localization","type":"exact"}],"termid":"GO:1903485"}


id: GO:0052512
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The increase by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation by organism of hormone or growth regulator levels in symbiont (obsolete GO:0052512)","synonyms":[{"name":"positive modulation of hormone or growth regulator levels in symbiont","type":"exact"},{"name":"positive regulation by organism of hormone or growth regulator levels in symbiont","type":"exact"}],"termid":"GO:0052512"}


id: MONDO:0800397
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inherited retinopathy caused by bi-allelic variants in the GRM6 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inherited retinal dystrophy","termid":"MONDO:0019118"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"GRM6-related retinopathy","termid":"MONDO:0800397","xrefs":{"Monarch":{"xref_id":"0800397"}}}


id: MONDO:0011401
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"early-onset autosomal dominant Alzheimer disease","termid":"MONDO:0015140"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002039"},{"rel_name":"is_a","termid":"MONDO:0000426"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0000426","MONDO:0002039","MONDO:0005559"],"is_obsolete":false,"name":"Alzheimer disease without neurofibrillary tangles","secondary_identifiers":["UMLS:C1858751","OMIM:604154","MEDGEN:346983","GARD:7190","MESH:C536599","OMIM:611155","DOID:0110048","MESH:C566998"],"synonyms":[{"name":"AD15","type":"exact"},{"name":"Alzheimer disease 15","type":"exact"},{"name":"Alzheimer disease without neurofibrillary tangles","type":"exact"},{"name":"Alzheimer disease-15","type":"exact"},{"name":"Alzheimer's disease 15","type":"exact"},{"name":"Alzheimer's disease type 15","type":"exact"},{"name":"Alzheimer's disease without neurofibrillary tangles","type":"related"}],"termid":"MONDO:0011401","xrefs":{"Monarch":{"xref_id":"0011401"}}}


id: GO:0052784
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.","definition_xrefs":["PMID:16000808","GOC:mengo_curators","PMID:15256553"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alpha-glucan biosynthetic process","termid":"GO:0030979"},{"relation_name":"is_a","term_name":"reuteran metabolic process","termid":"GO:0052783"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"reuteran biosynthetic process","synonyms":[{"name":"reuteransucrase-mediated reuteran biosynthesis","type":"narrow"}],"termid":"GO:0052784"}


id: PR:Q10208
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A pyruvate kinase I that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pyruvate kinase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC4H3.10c","secondary_identifiers":["UniProtKB:Q10208"],"synonyms":[{"name":"PK (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPAC4H3.10c","type":"related"},{"name":"Spom972h-pykF","type":"exact"}],"termid":"PR:Q10208"}


id: GO:2001062
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to xylan.","definition_xrefs":["GOC:mengo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide binding","termid":"GO:0030247"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"xylan binding","termid":"GO:2001062"}


id: FYPO:0006307
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which actin filament severing is decreased. Actin filament severing is the process in which an actin filament is broken down into smaller filaments.","definition_xrefs":["PomBase:mah","GO:0051014","PMID:22024167"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal actin filament-based process","termid":"FYPO:0006306"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"decreased actin filament severing","synonyms":[{"name":"decreased F-actin severing","type":"exact"},{"name":"decreased actin filament severing during mitotic cell cycle","type":"related"},{"name":"decreased actin filament severing during vegetative growth","type":"exact"},{"name":"reduced actin filament severing","type":"exact"}],"termid":"FYPO:0006307"}


id: GO:0061260
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.","definition_xrefs":["GOC:mtg_kidney_jan10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell differentiation involved in mesonephros development","termid":"GO:0061208"},{"relation_name":"is_a","term_name":"mesangial cell differentiation","termid":"GO:0072007"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesonephric mesangial cell differentiation","termid":"GO:0061260"}


id: GO:0047856
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H+.","definition_xrefs":["RHEA:10360"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0016787","GO:0003824","GO:0003674","GO:0016788"],"is_obsolete":false,"name":"dihydrocoumarin hydrolase activity","secondary_identifiers":["EC:3.1.1.35","KEGG_REACTION:R03692","MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN"],"synonyms":[{"name":"3,4-dihydrocoumarin hydrolase activity","type":"exact"},{"name":"dihydrocoumarin lactonohydrolase activity","type":"related"},{"name":"dihydrocoumarin lipase activity","type":"exact"}],"termid":"GO:0047856"}


id: GO:1904043
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity.","definition_xrefs":["PMID:24416422","GO_REF:0000059","GOC:hal","GOC:BHF","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete positive regulation of cystathionine beta-synthase activity (obsolete GO:1904043)","synonyms":[{"name":"activation of L-serine hydro-lyase (adding homocysteine)","type":"narrow"},{"name":"activation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)","type":"narrow"},{"name":"activation of beta-thionase activity","type":"narrow"},{"name":"activation of cystathionine beta-synthase activity","type":"narrow"},{"name":"activation of methylcysteine synthase activity","type":"narrow"},{"name":"activation of serine sulfhydrase activity","type":"narrow"},{"name":"activation of serine sulfhydrylase activity","type":"narrow"},{"name":"positive regulation of L-serine hydro-lyase (adding homocysteine)","type":"exact"},{"name":"positive regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)","type":"exact"},{"name":"positive regulation of beta-thionase activity","type":"exact"},{"name":"positive regulation of methylcysteine synthase activity","type":"exact"},{"name":"positive regulation of serine sulfhydrase activity","type":"exact"},{"name":"positive regulation of serine sulfhydrylase activity","type":"exact"},{"name":"up regulation of L-serine hydro-lyase (adding homocysteine)","type":"exact"},{"name":"up regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)","type":"exact"},{"name":"up regulation of beta-thionase activity","type":"exact"},{"name":"up regulation of cystathionine beta-synthase activity","type":"exact"},{"name":"up regulation of methylcysteine synthase activity","type":"exact"},{"name":"up regulation of serine sulfhydrase activity","type":"exact"},{"name":"up regulation of serine sulfhydrylase activity","type":"exact"},{"name":"up-regulation of L-serine hydro-lyase (adding homocysteine)","type":"exact"},{"name":"up-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)","type":"exact"},{"name":"up-regulation of beta-thionase activity","type":"exact"},{"name":"up-regulation of cystathionine beta-synthase activity","type":"exact"},{"name":"up-regulation of methylcysteine synthase activity","type":"exact"},{"name":"up-regulation of serine sulfhydrase activity","type":"exact"},{"name":"up-regulation of serine sulfhydrylase activity","type":"exact"},{"name":"upregulation of L-serine hydro-lyase (adding homocysteine)","type":"exact"},{"name":"upregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)","type":"exact"},{"name":"upregulation of beta-thionase activity","type":"exact"},{"name":"upregulation of cystathionine beta-synthase activity","type":"exact"},{"name":"upregulation of methylcysteine synthase activity","type":"exact"},{"name":"upregulation of serine sulfhydrase activity","type":"exact"},{"name":"upregulation of serine sulfhydrylase activity","type":"exact"}],"termid":"GO:1904043"}


id: PBO:0057583
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 888","termid":"PBO:0057583"}


id: GO:0002082
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.","definition_xrefs":["GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of aerobic respiration","termid":"GO:1903715"},{"relation_name":"regulates","term_name":"oxidative phosphorylation","termid":"GO:0006119"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0006091"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006091","GO:0008150"],"is_obsolete":false,"name":"regulation of oxidative phosphorylation","synonyms":[{"name":"OXPHOS","type":"exact"}],"termid":"GO:0002082"}


id: SO:0002121
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The configuration of the IG and TR variable (V), diversity (D) and joining (J) germline genes before DNA rearrangements (with or without constant (C) genes in undefined configuration. (germline, non rearranged regions of the IG DNA loci).","definition_xrefs":["IGMT:http://www.imgt.org/IMGTScientificChart/SequenceDescription/Keywords.php","GENCODE:http://www.gencodegenes.org/gencode_biotypes.html"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gene","termid":"SO:0000704"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"vertebrate_immune_system_gene","synonyms":[{"name":"immune_gene","type":"exact"}],"termid":"SO:0002121"}


id: PBO:0046196
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ELOA antisense RNA 1","termid":"PBO:0046196"}


id: GO:0031104
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The regrowth of dendrites in response to their loss or damage.","definition_xrefs":["GOC:tb","GOC:dph","GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"dendrite development","termid":"GO:0016358"},{"relation_name":"is_a","term_name":"neuron projection regeneration","termid":"GO:0031102"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"dendrite regeneration","termid":"GO:0031104"}


id: PBO:0050083
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group AT-hook 1 pseudogene 3","termid":"PBO:0050083"}


id: PBO:0068734
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U5A small nuclear 5, pseudogene","termid":"PBO:0068734"}


id: MONDO:0003076
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A retinoblastoma that only involves a single eye.","definition_xrefs":["NCIT:C8714"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinoblastoma","termid":"MONDO:0008380"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005328"],"is_obsolete":false,"name":"unilateral retinoblastoma","secondary_identifiers":["UMLS:C0854915","MEDGEN:208929","DOID:4651"],"termid":"MONDO:0003076","xrefs":{"Monarch":{"xref_id":"0003076"}}}


id: PBO:0085964
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein of unknown function; overexpression suppresses the high-frequency loss of mini-chromosomes, probably by increasing the rate of proper chromosome segregation; translated gene product of YCR041W, but not its transcript, is responsible for suppression; suppression ability of YCR041W is completely dependent on silencing protein Sir4p","termid":"PBO:0085964"}


id: PR:O42921
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A cytochrome c oxidase assembly factor 5 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO04058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial protein pet191 homolog (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC16A3.16","secondary_identifiers":["UniProtKB:O42921"],"synonyms":[{"name":"Spom972h-COA5","type":"exact"}],"termid":"PR:O42921"}


id: MOD:01840
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-isoleucine residue to L-allo-isoleucine.","definition_xrefs":["ChEBI:43433","PubMed:20805503","RESID:AA0546"],"direct_ancestors":[{"relation_name":"is_a","term_name":"stereoisomerized residue","termid":"MOD:00664"},{"relation_name":"is_a","term_name":"modified L-isoleucine residue","termid":"MOD:00910"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-allo-isoleucine","synonyms":[{"name":"(2S,3R)-2-amino-3-methylpentanoic acid","type":"exact"},{"name":"2-azanyl-3-methylpentanoic acid","type":"exact"},{"name":"3-methyl-norvaline","type":"exact"},{"name":"L-allo-isoleucine","type":"exact"},{"name":"L-threo-isoleucine","type":"exact"},{"name":"MOD_RES L-allo-isoleucine","type":"exact"},{"name":"allo-L-isoleucine","type":"exact"},{"name":"alpha-amino-beta-methylvaleric acid","type":"exact"}],"termid":"MOD:01840"}


id: PBO:0047286
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"FA complementation group M","termid":"PBO:0047286"}


id: PBO:0078124
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"T cell receptor alpha variable 8-6","termid":"PBO:0078124"}


id: GO:0000272
data:
  {"annotated_genes":["SJAG_00115","SJAG_02649","SJAG_04327","SJAG_02478","SJAG_03851","SJAG_04963","SJAG_00620","SJAG_02131","SJAG_02076","SJAG_01888","SJAG_01017","SJAG_03295","SJAG_03824","SJAG_03646","SJAG_01783","SJAG_01171","SJAG_05001","SJAG_01561","SJAG_06309","SJAG_00667","SJAG_03444"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[59017,68441,98024,98025,110377,117649],"is_not":false,"summary":null,"term":"GO:0000272"},{"annotations":[121665],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0030995"},{"annotations":[102085,95915],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0044347"},{"annotations":[72346,76871,72243,78841,75029],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0009251"},{"annotations":[105251],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005980"},{"annotations":[80640,73586,73848,74869,75161,81659],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061723"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.","definition_xrefs":["PMID:33139480"],"direct_ancestors":[{"relation_name":"is_a","term_name":"polysaccharide metabolic process","termid":"GO:0005976"},{"relation_name":"is_a","term_name":"macromolecule catabolic process","termid":"GO:0009057"},{"relation_name":"is_a","term_name":"carbohydrate catabolic process","termid":"GO:0016052"}],"gene_count":21,"genes_by_uniquename":{"SJAG_00115":null,"SJAG_00620":null,"SJAG_00667":null,"SJAG_01017":null,"SJAG_01171":null,"SJAG_01561":null,"SJAG_01783":null,"SJAG_01888":null,"SJAG_02076":null,"SJAG_02131":null,"SJAG_02478":null,"SJAG_02649":null,"SJAG_03295":null,"SJAG_03444":null,"SJAG_03646":null,"SJAG_03824":null,"SJAG_03851":null,"SJAG_04327":null,"SJAG_04963":null,"SJAG_05001":null,"SJAG_06309":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"polysaccharide catabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000043":null,"GO_REF:0000107":null,"PMID:24699070":null},"secondary_identifiers":["GO:0044244"],"synonyms":[{"name":"multicellular organismal polysaccharide catabolic process","type":"narrow"},{"name":"polysaccharide breakdown","type":"exact"},{"name":"polysaccharide catabolism","type":"exact"},{"name":"polysaccharide degradation","type":"exact"}],"termid":"GO:0000272","terms_by_termid":{"GO:0000272":null,"GO:0005980":null,"GO:0009251":null,"GO:0030995":null,"GO:0044347":null,"GO:0061723":null}}


id: PBO:0066933
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 235","termid":"PBO:0066933"}


id: GO:1900934
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process.","definition_xrefs":["GOC:mengo_curators","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of olefin metabolic process","termid":"GO:1900910"},{"relation_name":"is_a","term_name":"regulation of nonadec-1-ene metabolic process","termid":"GO:1900932"},{"relation_name":"positively_regulates","term_name":"nonadec-1-ene metabolic process","termid":"GO:1900876"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of nonadec-1-ene metabolic process","synonyms":[{"name":"activation of nonadec-1-ene metabolic process","type":"narrow"},{"name":"activation of nonadec-1-ene metabolism","type":"exact"},{"name":"positive regulation of nonadec-1-ene metabolism","type":"exact"},{"name":"up regulation of nonadec-1-ene metabolic process","type":"exact"},{"name":"up regulation of nonadec-1-ene metabolism","type":"exact"},{"name":"up-regulation of nonadec-1-ene metabolic process","type":"exact"},{"name":"up-regulation of nonadec-1-ene metabolism","type":"exact"},{"name":"upregulation of nonadec-1-ene metabolic process","type":"exact"},{"name":"upregulation of nonadec-1-ene metabolism","type":"exact"}],"termid":"GO:1900934"}


id: MONDO:0020622
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete blood group--stoltzfus system (obsolete MONDO:0020622)","secondary_identifiers":["OMIM:111800"],"synonyms":[{"name":"BLOOD GROUP--STOLTZFUS SYSTEM","type":"related"},{"name":"Sf","type":"related"},{"name":"blood group, Stoltzfus system","type":"exact"}],"termid":"MONDO:0020622","xrefs":{"Monarch":{"xref_id":"0020622"}}}


id: MONDO:1011078
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Urolithiasis that occurs in dog.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"urolithiasis, non-human animal","termid":"MONDO:1010267"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"urolithiasis, dog","secondary_identifiers":["OMIA:001033-9615"],"termid":"MONDO:1011078","xrefs":{"Monarch":{"xref_id":"1011078"}}}


id: PBO:0082335
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases; null mutant is sensitive to expression of the top1-T722A allele","termid":"PBO:0082335"}


id: PR:O94594
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC622.04 gene.","definition_xrefs":["UniProtKB:O94594","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized membrane protein C622.04 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC622.04","synonyms":[{"name":"Spom972h-SPCC622.04","type":"exact"}],"termid":"PR:O94594"}


id: GO:0047892
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.","definition_xrefs":["EC:2.4.2.25","MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN"],"direct_ancestors":[{"relation_name":"is_a","term_name":"UDP-glycosyltransferase activity","termid":"GO:0008194"},{"relation_name":"is_a","term_name":"pentosyltransferase activity","termid":"GO:0016763"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016757"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016740"}],"interesting_parent_ids":["GO:0016740","GO:0003824","GO:0003674","GO:0016757"],"is_obsolete":false,"name":"flavone apiosyltransferase activity","secondary_identifiers":["RHEA:19153"],"synonyms":[{"name":"UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity","type":"related"},{"name":"UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity","type":"related"},{"name":"uridine diphosphoapiose-flavone apiosyltransferase activity","type":"related"}],"termid":"GO:0047892"}


id: GO:0018343
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The covalent attachment of a farnesyl group to a protein.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein prenylation","termid":"GO:0018342"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein farnesylation","secondary_identifiers":["GO:0018347"],"synonyms":[{"name":"C-terminal protein farnesylation","type":"narrow"},{"name":"protein amino acid farnesylation","type":"exact"}],"termid":"GO:0018343"}


id: GO:0019464
data:
  {"annotated_genes":["SJAG_03641","SJAG_02901","SJAG_03861"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75942,79835,98326],"is_not":false,"summary":null,"term":"GO:0019464"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.","definition_xrefs":["MetaCyc:GLYCLEAV-PWY"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glycine catabolic process","termid":"GO:0006546"},{"relation_name":"is_a","term_name":"ammonium ion metabolic process","termid":"GO:0097164"}],"gene_count":3,"genes_by_uniquename":{"SJAG_02901":null,"SJAG_03641":null,"SJAG_03861":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006520"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006520","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"glycine decarboxylation via glycine cleavage system","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"glycine cleavage system","type":"broad"}],"termid":"GO:0019464","terms_by_termid":{"GO:0019464":null}}


id: PBO:0053922
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1219","termid":"PBO:0053922"}


id: PBO:0027983
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-inviable_after_spore_germination,_multiple_cell_divisions,_small_cell_with_abnormal_septum_morphology","termid":"PBO:0027983"}


id: PBO:0075251
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sorting nexin 18 pseudogene 3","termid":"PBO:0075251"}


id: PBO:0078822
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Pro (anticodon AGG) 2-5","termid":"PBO:0078822"}


id: PBO:0074383
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SMG6 nonsense mediated mRNA decay factor","termid":"PBO:0074383"}


id: PATO:0001589
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"Increased, intensified.","definition_xrefs":["PATOC:GVG"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0001589 enhanced (obsolete PATO:0001589)","termid":"PATO:0001589"}


id: PBO:0049610
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"H3 histone pseudogene 13","termid":"PBO:0049610"}


id: PBO:0078280
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Cys (anticodon GCA) 13-1","termid":"PBO:0078280"}


id: PBO:0054574
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1976","termid":"PBO:0054574"}


id: PBO:0014284
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"trimin, ribonuclease involved in priRNA formation Tri1","termid":"PBO:0014284"}


id: MOD:00285
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively results from forming an adduct between an aspartic acid residue, a glutamic acid residue, a methionine residue (forming a sulfonium ether), and the porphyrin compound heme b, (7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoato)iron.","definition_xrefs":["RESID:AA0280","PubMed:10447690","PubMed:7840679","PubMed:1320128","PubMed:10480885"],"direct_ancestors":[{"relation_name":"is_a","term_name":"porphyrin modified residue","termid":"MOD:00699"},{"relation_name":"is_a","term_name":"metal or metal cluster coordinated L-aspartic acid residue","termid":"MOD:02066"},{"relation_name":"is_a","term_name":"metal or metal cluster coordinated L-glutamic acid residue","termid":"MOD:02068"},{"relation_name":"is_a","term_name":"metal or metal cluster coordinated L-methionine residue","termid":"MOD:02071"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dihydroxyheme-L-aspartate ester-L-glutamate ester-L-methionine sulfonium","synonyms":[{"name":"1,5-bishydroxymethyl protoporphyrin IX 1-glutamate ester 5-aspartate ester 2-methionine sulfonium","type":"exact"},{"name":"BINDING Heme (covalent; via 3 links)","type":"exact"},{"name":"[13-[(S)-(4-amino-4-carboxy)butanoyloxymethyl]-3-[(S)-(3-amino-3-carboxy)propanoyloxymethyl]-12-[(S)-(3-amino-3-carboxy)propylsulfoniumethyl]-7-ethenyl-8,17-dimethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrate","type":"exact"},{"name":"dihydroxyheme-L-aspartate ester-L-glutamate ester-L-methionine sulfonium","type":"exact"},{"name":"myeloperoxidase heme cofactor","type":"exact"}],"termid":"MOD:00285"}


id: PBO:0049856
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HECT domain E3 ubiquitin protein ligase 4","termid":"PBO:0049856"}


id: PBO:0110230
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TORC1/2 complex WD repeat protein Wat1/Lst8","termid":"PBO:0110230"}


id: PBO:0075898
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ST7 overlapping transcript 4","termid":"PBO:0075898"}


id: GO:0120126
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion.","definition_xrefs":["PMID:24024382","GOC:sl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to metal ion starvation","termid":"GO:0180055"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"response to copper ion starvation","termid":"GO:0120126"}


id: PATO:0000355
data:
  {"annotation_feature_type":"gene","cv_name":"quality","gene_count":0,"genotype_count":0,"name":"OBSOLETE PATO:0000355 enzyme composition value (obsolete PATO:0000355)","termid":"PATO:0000355"}


id: GO:0045864
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine.","definition_xrefs":["GOC:go_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of metabolic process","termid":"GO:0009893"},{"relation_name":"is_a","term_name":"regulation of pteridine metabolic process","termid":"GO:0042068"},{"relation_name":"positively_regulates","term_name":"pteridine metabolic process","termid":"GO:0019889"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of pteridine metabolic process","synonyms":[{"name":"activation of pteridine metabolic process","type":"narrow"},{"name":"positive regulation of pteridine metabolism","type":"exact"},{"name":"stimulation of pteridine metabolic process","type":"narrow"},{"name":"up regulation of pteridine metabolic process","type":"exact"},{"name":"up-regulation of pteridine metabolic process","type":"exact"},{"name":"upregulation of pteridine metabolic process","type":"exact"}],"termid":"GO:0045864"}


id: PBO:0075406
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"sperm acrosome associated 4","termid":"PBO:0075406"}


id: PBO:0049475
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"granzyme M","termid":"PBO:0049475"}


id: SO:1000061
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The amino acid change following from the codon change changes the gross properties (size, charge, hydrophobicity) of the amino acid in that position.","definition_xrefs":["EBI:www.ebi.ac.uk/mutations/recommendations/mutevent.html"],"gene_count":0,"genotype_count":0,"name":"OBSOLETE SO:1000061 sequence_variant_causing_nonconservative_missense_codon_change_in_transcript (obsolete SO:1000061)","synonyms":[{"name":"mutation causing nonconservative missense codon change in transcript","type":"related"},{"name":"sequence variant causing nonconservative missense codon change in transcript","type":"exact"}],"termid":"SO:1000061"}


id: PBO:0041471
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chromosome 11 putative open reading frame 40","termid":"PBO:0041471"}


id: PBO:0075188
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"small nuclear ribonucleoprotein polypeptide G","termid":"PBO:0075188"}


id: PBO:0064254
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pleckstrin homology domain containing A3","termid":"PBO:0064254"}


id: MONDO:0032851
data:
  {"annotated_genes":["SJAG_03157"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88706],"is_not":false,"summary":null,"term":"MONDO:0032851"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":1,"genes_by_uniquename":{"SJAG_03157":null},"genotype_count":0,"is_obsolete":false,"name":"intellectual developmental disorder with impaired language and dysmorphic facies","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C5231444","OMIM:618653","MEDGEN:1684804","GARD:18520"],"synonyms":[{"name":"IDDILF","type":"related"},{"name":"INTELLECTUAL DEVELOPMENTAL DISORDER WITH IMPAIRED LANGUAGE AND DYSMORPHIC FACIES","type":"related"}],"termid":"MONDO:0032851","terms_by_termid":{"MONDO:0032851":null},"xrefs":{"Monarch":{"xref_id":"0032851"}}}


id: PBO:0084168
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Highly conserved subunit of the mitochondrial pyruvate carrier (MPC); expressed during growth on nonfermentable carbon sources, and heterodimerizes with Mpc1p to form the respiratory isoform of MPC; MPC localizes to the mitochondrial inner membrane and mediates pyruvate uptake; MPC3 paralog, MPC2, heterodimerizes with Mpc1p to form the fermentative MPC isoform; protein abundance increases in response to DNA replication stress","termid":"PBO:0084168"}


id: PBO:0087690
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP107","termid":"PBO:0087690"}


id: GO:0001760
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H+ = 2-aminomuconate 6-semialdehyde + CO2.","definition_xrefs":["EC:4.1.1.45","RHEA:16557"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carboxy-lyase activity","termid":"GO:0016831"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016829"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016829"],"is_obsolete":false,"name":"aminocarboxymuconate-semialdehyde decarboxylase activity","secondary_identifiers":["MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN","KEGG_REACTION:R04323"],"synonyms":[{"name":"2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)","type":"related"},{"name":"2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity","type":"related"},{"name":"2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity","type":"related"},{"name":"ACMSD activity","type":"exact"},{"name":"alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity","type":"related"},{"name":"alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity","type":"related"},{"name":"picolinic acid carboxylase activity","type":"related"},{"name":"picolinic acid decarboxylase activity","type":"related"}],"termid":"GO:0001760"}


id: PBO:0045395
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"developmental pluripotency associated 2 pseudogene 2","termid":"PBO:0045395"}


id: MONDO:0044349
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An instance of hemoglobinopathy that is acquired during the lifetime of the individual.","definition_xrefs":["MONDO:patterns/acquired"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hemoglobinopathy","termid":"MONDO:0044348"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"}],"interesting_parent_ids":["MONDO:0005570"],"is_obsolete":false,"name":"acquired hemoglobinopathy","secondary_identifiers":["SCTID:127039000","MEDGEN:688237","UMLS:C1263995"],"synonyms":[{"name":"acquired hemoglobinopathy","type":"exact"}],"termid":"MONDO:0044349","xrefs":{"Monarch":{"xref_id":"0044349"}}}


id: PBO:0066839
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RN7SK pseudogene 139","termid":"PBO:0066839"}


id: GO:0015179
data:
  {"annotated_genes":["SJAG_04725","SJAG_04637","SJAG_03400","SJAG_02029","SJAG_00543","SJAG_00522","SJAG_03899","SJAG_04718","SJAG_04588","SJAG_03256"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[98488],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000515"},{"annotations":[97939],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0034639"},{"annotations":[102297,80925,99278],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061459"},{"annotations":[104751,112020],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015182"},{"annotations":[80920],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005313"},{"annotations":[80918,99279],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005290"},{"annotations":[112021,104752],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015188"},{"annotations":[99280,102298,104753,112022,80922],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015189"},{"annotations":[109884],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000064"},{"annotations":[102290],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015193"},{"annotations":[80923,92499],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0015194"},{"annotations":[80919],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0005302"}]},"cv_name":"molecular_function","definition":"Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.","definition_xrefs":["GOC:jsg","GOC:mah","ISBN:0815340729","GOC:mtg_transport","GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"amino acid transmembrane transporter activity","termid":"GO:0015171"},{"relation_name":"is_a","term_name":"carboxylic acid transmembrane transporter activity","termid":"GO:0046943"}],"gene_count":10,"genes_by_uniquename":{"SJAG_00522":null,"SJAG_00543":null,"SJAG_02029":null,"SJAG_03256":null,"SJAG_03400":null,"SJAG_03899":null,"SJAG_04588":null,"SJAG_04637":null,"SJAG_04718":null,"SJAG_04725":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0003674","GO:0005215","GO:0022857"],"is_obsolete":false,"name":"L-amino acid transmembrane transporter activity","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-212614"],"synonyms":[{"name":"L-amino acid transporter activity","type":"broad"}],"termid":"GO:0015179","terms_by_termid":{"GO:0000064":null,"GO:0000515":null,"GO:0005290":null,"GO:0005302":null,"GO:0005313":null,"GO:0015182":null,"GO:0015188":null,"GO:0015189":null,"GO:0015193":null,"GO:0015194":null,"GO:0034639":null,"GO:0061459":null}}


id: PBO:0051189
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy variable 3/OR16-7 (pseudogene)","termid":"PBO:0051189"}


id: MONDO:0016080
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Congenital respiratory-biliary fistula (RBF) is a rare developmental defect characterized by an anomalous connection of trachea or bronchus with left hepatic duct presenting with respiratory distress, recurrent respiratory infections and biliary expectoration or vomitus.","definition_xrefs":["Orphanet:2040"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system disorder","termid":"MONDO:0005087"},{"relation_name":"is_a","term_name":"disorder of development or morphogenesis","termid":"MONDO:0021147"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital bronchobiliary fistula","secondary_identifiers":["icd11.foundation:420429663","GARD:1475","SCTID:719452004","UMLS:C4304716","MEDGEN:930385"],"termid":"MONDO:0016080","xrefs":{"Monarch":{"xref_id":"0016080"}}}


id: PBO:0003181
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"horsetail movement protein Hrs1/Mcp6","termid":"PBO:0003181"}


id: MONDO:0006533
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A non-neoplastic lesion characterized by the proliferation of keratinizing squamous epithelium in the middle ear that results in the accumulation of keratin and cells. It is usually caused by repeated infections. If left untreated, it may increase in size and destroy the adjacent delicate bones of the middle ear.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"middle ear disorder","termid":"MONDO:0003276"},{"relation_name":"is_a","term_name":"cholesteatoma","termid":"MONDO:0006530"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005093"}],"interesting_parent_ids":["MONDO:0005093"],"is_obsolete":false,"name":"cholesteatoma of middle ear","secondary_identifiers":["MESH:D018424","ICD9:385.3","SCTID:194339007","NCIT:C3654","ICD9:385.33","icd11.foundation:2134365487","UMLS:C0155490","DOID:10964","EFO:1000678","ICD10CM:H71","ICD9:385.32","MEDGEN:57836"],"synonyms":[{"name":"Epidermosis of ear","type":"exact"},{"name":"Epidermosis of middle ear","type":"exact"},{"name":"cholesteatoma (disease) of middle ear","type":"exact"},{"name":"cholesteatoma of middle ear","type":"exact"},{"name":"cholesteatoma of middle ear and mastoid","type":"exact"},{"name":"cholesteatoma of middle ear and/or mastoid","type":"exact"},{"name":"cholesteatoma of the middle ear","type":"exact"},{"name":"middle ear cholesteatoma","type":"exact"},{"name":"middle ear cholesteatoma (disease)","type":"exact"},{"name":"unspecified cholesteatoma (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0006533","xrefs":{"Monarch":{"xref_id":"0006533"}}}


id: GO:0023042
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator.","definition_xrefs":["GOC:mtg_signal"],"gene_count":0,"genotype_count":0,"name":"obsolete signaling via protein/peptide mediator (obsolete GO:0023042)","synonyms":[{"name":"signaling via protein/peptide mediator","type":"exact"},{"name":"signalling via protein/peptide mediator","type":"exact"}],"termid":"GO:0023042"}


id: MOD:00215
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively cross-links an L-serine residue to the polymer heparan sulfate by a D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl tetrasaccharide.","definition_xrefs":["RESID:AA0210","PubMed:3472204"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-glycosyl-L-serine","termid":"MOD:00002"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"heparan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine","synonyms":[{"name":"heparan sulfate D-glucuronosyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine","type":"exact"},{"name":"heparin","type":"exact"},{"name":"heparitin sulfate","type":"exact"},{"name":"poly[alpha-1,4-(2-sulfate D-glucopyranuronosyl)-beta-1,4-(2-sulfamino-2-deoxy-6-sulfate D-glucosyl)]-beta-1,4-D-glucopyranuronosyl-beta-1,3-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-D-xylosyl-beta-1,3-L-serine","type":"exact"}],"termid":"MOD:00215"}


id: PBO:0058068
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 4287","termid":"PBO:0058068"}


id: PBO:0084879
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosome-associated protein; regulates mitochondrial DNA copy number and the size and distribution of mtDNA nucleoids; subunit of a complex containing Pet20p, Mam33p, and Pim1p that may regulate mtDNA replication; member of the PET20 domain-containing protein family; forms foci that partially co-localize with mtDNA","termid":"PBO:0084879"}


id: PBO:0040123
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ankyrin repeat and SOCS box containing 9 pseudogene 1","termid":"PBO:0040123"}


id: FYPO:0003859
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to wortmannin. Cells stop growing (and may die) at a concentration of wortmannin that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002683"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0005447","FYPO:0000139","FYPO:0002683","FYPO:0001985"],"is_obsolete":false,"name":"sensitive to wortmannin","synonyms":[{"name":"hypersensitive to wortmannin","type":"exact"},{"name":"sensitive to wortmannin during mitotic cell cycle","type":"related"},{"name":"sensitive to wortmannin during vegetative growth","type":"exact"}],"termid":"FYPO:0003859"}


id: GO:0018524
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate.","definition_xrefs":["UM-BBD_reactionID:r0033"],"gene_count":0,"genotype_count":0,"name":"obsolete acetophenone carboxylase activity (obsolete GO:0018524)","termid":"GO:0018524"}


id: PBO:0046593
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"endogenous retrovirus group K3 member 3","termid":"PBO:0046593"}


id: PBO:0077061
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"thrombospondin type 1 domain containing 7B","termid":"PBO:0077061"}


id: FYPO:0003135
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell adhesion phenotype in which cells adhere to other cells of compatible mating type normally (i.e. agglutination is indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal cellular process","termid":"FYPO:0000627"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal agglutination","synonyms":[{"name":"normal agglutination involved in conjugation with cellular fusion","type":"exact"}],"termid":"FYPO:0003135"}


id: PBO:0061990
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 2 subfamily BH member 1 pseudogene","termid":"PBO:0061990"}


id: GO:0052573
data:
  {"annotated_genes":["SJAG_02951","SJAG_02954","SJAG_01784","SJAG_03818"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[115727,111583,115735,115734],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0052574"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"nucleotide-sugar metabolic process","termid":"GO:0009225"}],"gene_count":4,"genes_by_uniquename":{"SJAG_01784":null,"SJAG_02951":null,"SJAG_02954":null,"SJAG_03818":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0055086"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"}],"interesting_parent_ids":["GO:0055086","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"UDP-D-galactose metabolic process","references_by_uniquename":{"GO_REF:0000107":null},"synonyms":[{"name":"UDP-D-galactopyranose metabolic process","type":"exact"},{"name":"UDP-D-galactopyranose metabolism","type":"exact"},{"name":"UDP-D-galactose metabolism","type":"exact"},{"name":"UDP-galactose metabolic process","type":"exact"},{"name":"UDP-galactose metabolism","type":"exact"},{"name":"uridine diphosphate galactose metabolic process","type":"exact"},{"name":"uridine diphosphate galactose metabolism","type":"exact"}],"termid":"GO:0052573","terms_by_termid":{"GO:0052574":null}}


id: MONDO:0016472
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Dracunculiasis (Guinea worm disease) is a neglected tropical disease (NTD) characterized by a painful burning skin lesion from which the Dracunculus medinensis parasite emerges approximately 1 year after infection resulting from consumption of unsafe drinking water containing parasite-infected copepods (Cyclops spp., microcrustacea also called water fleas).","definition_xrefs":["Orphanet:231"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Rhabditida infectious disease","termid":"MONDO:0005943"},{"relation_name":"is_a","term_name":"filariasis","termid":"MONDO:0016075"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dracunculiasis","secondary_identifiers":["MedDRA:10013618","DOID:14418","NCIT:C84677","MESH:D004320","MEDGEN:41653","ICD10CM:B72","ICD9:125.7","NORD:1060","SCTID:396334002","UMLS:C0013100","EFO:0007241","GARD:6286","icd11.foundation:1662537619"],"synonyms":[{"name":"Dracunculosis","type":"exact"},{"name":"Dracunculus medinensis caused disease or disorder","type":"exact"},{"name":"Dracunculus medinensis disease or disorder","type":"exact"},{"name":"Dracunculus medinensis infectious disease","type":"exact"},{"name":"GWD","type":"related"},{"name":"Guinea worm disease","type":"exact"},{"name":"Guinea worm infection","type":"related"},{"name":"Medina worm disease","type":"exact"},{"name":"dracontiasis","type":"exact"},{"name":"infection by Dracunculus medinensis","type":"exact"},{"name":"medinensis","type":"exact"},{"name":"parasitic infection caused by Dracunculus medinensis","type":"related"}],"termid":"MONDO:0016472","xrefs":{"Monarch":{"xref_id":"0016472"}}}


id: GO:0018214
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The addition of a carboxy group to a protein amino acid.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification process","termid":"GO:0036211"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"protein carboxylation","synonyms":[{"name":"protein amino acid carboxylation","type":"exact"}],"termid":"GO:0018214"}


id: MONDO:0003974
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete malignant triton tumor (obsolete MONDO:0003974)","termid":"MONDO:0003974","xrefs":{"Monarch":{"xref_id":"0003974"}}}


id: PBO:0077770
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TOMM22 pseudogene 6","termid":"PBO:0077770"}


id: PBO:0065645
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein tyrosine phosphatase non-receptor type 23","termid":"PBO:0065645"}


id: MONDO:0100214
data:
  {"annotated_genes":["SJAG_02206","SJAG_03626"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88913],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0100215"},{"annotations":[87697],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0100220"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"},{"relation_name":"is_a","term_name":"interstitial lung disease","termid":"MONDO:0015925"}],"gene_count":2,"genes_by_uniquename":{"SJAG_02206":null,"SJAG_03626":null},"genotype_count":0,"is_obsolete":false,"name":"Rajab interstitial lung disease with brain calcifications","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:462260","OMIMPS:613658","UMLS:C3150910"],"termid":"MONDO:0100214","terms_by_termid":{"MONDO:0100215":null,"MONDO:0100220":null},"xrefs":{"Monarch":{"xref_id":"0100214"}}}


id: MOD:00839
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes atoms of particular common isotopes with atoms of or groups containing deuteriumm, (2)H.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"isotope labeled residue","termid":"MOD:00702"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"(2)H deuterium labeled residue","termid":"MOD:00839"}


id: MONDO:0008940
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete endosteal sclerosis-cerebellar hypoplasia syndrome (obsolete MONDO:0008940)","termid":"MONDO:0008940","xrefs":{"Monarch":{"xref_id":"0008940"}}}


id: MONDO:0030915
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An autosomal recessive non-syndromic intellectual disability that has material basis in an autosomal recessive mutation of the RUSC2 gene on chromosome 9p13.","definition_xrefs":["DOID:0080239"],"direct_ancestors":[{"relation_name":"is_a","term_name":"autosomal recessive non-syndromic intellectual disability","termid":"MONDO:0019502"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0037792"},{"rel_name":"is_a","termid":"MONDO:0006025"}],"interesting_parent_ids":["MONDO:0037792","MONDO:0006025","MONDO:0005066"],"is_obsolete":false,"name":"intellectual disability, autosomal recessive 61","secondary_identifiers":["UMLS:C4540424","MEDGEN:1622296","OMIM:617773"],"synonyms":[{"name":"Alwadei syndrome","type":"related"},{"name":"MRT61","type":"related"},{"name":"autosomal recessive intellectual disability 61","type":"related"},{"name":"autosomal recessive mental retardation 61","type":"related"},{"name":"intellectual disability, autosomal recessive 61","type":"exact"},{"name":"mental retardation, autosomal recessive 61","type":"related"}],"termid":"MONDO:0030915","xrefs":{"Monarch":{"xref_id":"0030915"}}}


id: GO:0008942
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: NH4+ + 3 NAD(P)+ + 2 H2O = nitrite + 3 NAD(P)H + 5 H+.","definition_xrefs":["EC:1.7.1.4","PMID:31961593"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor","termid":"GO:0046857"},{"relation_name":"is_a","term_name":"nitrite reductase activity","termid":"GO:0098809"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"nitrite reductase [NAD(P)H] activity","secondary_identifiers":["KEGG_REACTION:R00787","KEGG_REACTION:R00789","MetaCyc:RXN0-6377"],"synonyms":[{"name":"NAD(P)H2:nitrite oxidoreductase activity","type":"related"},{"name":"NAD(P)H:nitrite oxidoreductase activity","type":"related"},{"name":"NADH-nitrite oxidoreductase activity","type":"related"},{"name":"NADPH-nitrite reductase activity","type":"related"},{"name":"ammonium-hydroxide:NAD(P)+ oxidoreductase activity","type":"related"},{"name":"assimilatory nitrite reductase activity","type":"related"},{"name":"nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity","type":"related"},{"name":"nitrite reductase [NAD(P)H2]","type":"related"}],"termid":"GO:0008942"}


id: FYPO:0000089
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methyl methanesulfonate. Cells stop growing (and may die) at a concentration of methyl methanesulfonate that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensitive to DNA damaging agents","termid":"FYPO:0000266"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001985","FYPO:0000003","FYPO:0000139","FYPO:0002683"],"is_obsolete":false,"name":"sensitive to methyl methanesulfonate","synonyms":[{"name":"hypersensitive to methyl methanesulfonate","type":"exact"},{"name":"sensitive to MMS","type":"exact"},{"name":"sensitive to methyl methanesulfonate during mitotic cell cycle","type":"related"},{"name":"sensitive to methyl methanesulfonate during vegetative growth","type":"exact"},{"name":"sensitive to methyl methanesulphonate","type":"exact"}],"termid":"FYPO:0000089"}


id: PBO:0003462
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mRNA processing protein (predicted)","termid":"PBO:0003462"}


id: GO:0140239
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.","definition_xrefs":["PMID:12839988"],"direct_ancestors":[{"relation_name":"is_a","term_name":"endocytosis","termid":"GO:0006897"},{"relation_name":"is_a","term_name":"establishment of localization in cell","termid":"GO:0051649"},{"relation_name":"is_a","term_name":"vesicle-mediated transport in synapse","termid":"GO:0099003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016192"},{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0016192","GO:0006810","GO:0051179"],"is_obsolete":false,"name":"postsynaptic endocytosis","termid":"GO:0140239"}


id: PBO:0030117
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-increased_protein_level_during_cellular_response_to_zinc_ion_starvation","termid":"PBO:0030117"}


id: MONDO:0001646
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Mild to moderate high blood pressure that is caused by an underlying medical condition.","definition_xrefs":["NCIT:P378"],"direct_ancestors":[{"relation_name":"is_a","term_name":"secondary hypertension","termid":"MONDO:0001200"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"benign secondary hypertension","secondary_identifiers":["ICD9:405.1","MEDGEN:57610","DOID:13143","ICD9:405.19","SCTID:194785008","UMLS:C0155620"],"termid":"MONDO:0001646","xrefs":{"Monarch":{"xref_id":"0001646"}}}


id: MONDO:1010330
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Keratitis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"disorder of orbital region, non-human animal","termid":"MONDO:1011315"},{"relation_name":"is_a","term_name":"disorder of visual system, non-human animal","termid":"MONDO:1011316"},{"relation_name":"is_a","term_name":"inflammatory disease, non-human animal","termid":"MONDO:1011327"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"keratitis, non-human animal","secondary_identifiers":["OMIA:001287"],"termid":"MONDO:1010330","xrefs":{"Monarch":{"xref_id":"1010330"}}}


id: GO:0034971
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete histone H3-R17 methylation (obsolete GO:0034971)","synonyms":[{"name":"histone H3 R17 methylation","type":"exact"},{"name":"histone H3R17me","type":"exact"},{"name":"histone lysine H3 R17 methylation","type":"exact"}],"termid":"GO:0034971"}


id: GO:1905623
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of leaf development.","definition_xrefs":["GO_REF:0000058","GOC:TermGenie","PMID:11606552"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of developmental process","termid":"GO:0051094"},{"relation_name":"is_a","term_name":"positive regulation of multicellular organismal process","termid":"GO:0051240"},{"relation_name":"is_a","term_name":"regulation of leaf development","termid":"GO:2000024"},{"relation_name":"positively_regulates","term_name":"leaf development","termid":"GO:0048366"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of leaf development","synonyms":[{"name":"activation of leaf development","type":"narrow"},{"name":"up regulation of leaf development","type":"exact"},{"name":"up-regulation of leaf development","type":"exact"},{"name":"upregulation of leaf development","type":"exact"}],"termid":"GO:1905623"}


id: FYPO:0007661
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during metaphase of meiosis I.","definition_xrefs":["PMID:11331883","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal protein localization to kinetochore during meiosis I","termid":"FYPO:0004214"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000138","FYPO:0000002","FYPO:0000257"],"is_obsolete":false,"name":"normal protein localization to kinetochore during meiotic metaphase I","synonyms":[{"name":"normal protein localisation to kinetochore during meiotic metaphase I","type":"exact"},{"name":"normal protein localization to kinetochore during meiosis I metaphase","type":"exact"}],"termid":"FYPO:0007661"}


id: GO:1901916
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis.","definition_xrefs":["PMID:22573892","GOC:dph","GOC:TermGenie"],"gene_count":0,"genotype_count":0,"name":"obsolete protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis (obsolete GO:1901916)","synonyms":[{"name":"protamine kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis","type":"narrow"},{"name":"protamine kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis","type":"narrow"},{"name":"protein kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis","type":"exact"}],"termid":"GO:1901916"}


id: PATO:0002328
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"An angle which is relatively low.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"decreased position","termid":"PATO:0001476"},{"relation_name":"is_a","term_name":"angle","termid":"PATO:0002326"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased angle to","termid":"PATO:0002328"}


id: PBO:0069656
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 933, pseudogene","termid":"PBO:0069656"}


id: GO:0002396
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.","definition_xrefs":["PMID:15928678","GOC:add","ISBN:0781735149","PMID:15771591"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"part_of","termid":"GO:0044085"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0044085","GO:0065003","GO:0008150"],"is_obsolete":false,"name":"MHC protein complex assembly","termid":"GO:0002396"}


id: PBO:0087289
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Silenced copy of a2 at HMR; similarity to Alpha2p; required along with a1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system","termid":"PBO:0087289"}


id: GO:0018940
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"phenol-containing compound metabolic process","termid":"GO:0018958"},{"relation_name":"is_a","term_name":"secondary metabolic process","termid":"GO:0019748"},{"relation_name":"is_a","term_name":"toluene-containing compound metabolic process","termid":"GO:0072490"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0019748"],"is_obsolete":false,"name":"orcinol metabolic process","secondary_identifiers":["UM-BBD_pathwayID:orc","MetaCyc:P342-PWY"],"synonyms":[{"name":"orcin metabolic process","type":"exact"},{"name":"orcin metabolism","type":"exact"},{"name":"orcinol metabolism","type":"exact"}],"termid":"GO:0018940"}


id: SO:0001439
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"A non-polar, hydorophobic amino acid encoded by the codons CCN (CCT, CCC, CCA and CCG).","direct_ancestors":[{"relation_name":"is_a","term_name":"amino_acid","termid":"SO:0001237"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"proline","synonyms":[{"name":"P","type":"exact"},{"name":"Pro","type":"exact"}],"termid":"SO:0001439"}


id: PBO:0089810
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNAJ domain protein Caj1/Djp1 type","termid":"PBO:0089810"}


id: MONDO:0018532
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete adenocarcinoma of liver and intrahepatic biliary tract (obsolete MONDO:0018532)","secondary_identifiers":["Orphanet:424943"],"synonyms":[{"name":"adenocarcinoma of liver and IBT","type":"exact"},{"name":"adenocarcinoma of the liver and IBT","type":"exact"},{"name":"adenocarcinoma of the liver and intrahepatic biliary tract","type":"exact"}],"termid":"MONDO:0018532","xrefs":{"Monarch":{"xref_id":"0018532"}}}


id: MONDO:0011087
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An inflammatory bowel disease that has material basis in variation in the chromosome region 12p13.2-q24.1.","definition_xrefs":["DOID:0110900","PMID:8841195"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inflammatory bowel disease","termid":"MONDO:0005265"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004335"},{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0004335","MONDO:0005046"],"is_obsolete":false,"name":"inflammatory bowel disease 2","secondary_identifiers":["OMIM:601458","UMLS:C1832321","MESH:C563310","MEDGEN:321934"],"synonyms":[{"name":"IBD2","type":"exact"},{"name":"inflammatory bowel disease 2","type":"exact"},{"name":"inflammatory bowel disease type 2","type":"exact"}],"termid":"MONDO:0011087","xrefs":{"Monarch":{"xref_id":"0011087"}}}


id: PBO:0016559
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Meiotic Rna Binding protein","termid":"PBO:0016559"}


id: PBO:0029650
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_nucleus_location","termid":"PBO:0029650"}


id: PBO:0045118
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DMRT like family A2","termid":"PBO:0045118"}


id: PBO:0050130
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"high mobility group box 1 pseudogene 40","termid":"PBO:0050130"}


id: PBO:0025471
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinetochore protein, CENP-L ortholog Fta1","termid":"PBO:0025471"}


id: MONDO:1010043
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Cystic fibrosis that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"respiratory system disorder, non-human animal","termid":"MONDO:0700104"},{"relation_name":"is_a","term_name":"hereditary disease, non-human animal","termid":"MONDO:1011321"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cystic fibrosis, non-human animal","secondary_identifiers":["OMIA:001794"],"termid":"MONDO:1010043","xrefs":{"Monarch":{"xref_id":"1010043"}}}


id: GO:0102393
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein = FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF.","definition_xrefs":["GOC:pz"],"gene_count":0,"genotype_count":0,"name":"obsolete decanoyl-[acp] 2-dehydrogenase activity (obsolete GO:0102393)","termid":"GO:0102393"}


id: MONDO:0005722
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Acute upper respiratory airways infection that results in the swelling of the larynx. It is usually caused by parainfluenza viruses. Signs include a characteristic barking cough and stridor.","definition_xrefs":["NCIT:C26735"],"direct_ancestors":[{"relation_name":"is_a","term_name":"laryngotracheitis","termid":"MONDO:0000263"},{"relation_name":"is_a","term_name":"bronchitis","termid":"MONDO:0003781"},{"relation_name":"is_a","term_name":"acute laryngitis","termid":"MONDO:0004777"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"croup","secondary_identifiers":["SCTID:71186008","MESH:D003440","ICD9:464.4","MEDGEN:3668","DOID:9395","UMLS:C0010380","EFO:0007227"],"synonyms":[{"name":"acute laryngotracheitis","type":"related"},{"name":"acute laryngotracheobronchitis","type":"exact"},{"name":"acute obstructive laryngitis","type":"exact"},{"name":"croup syndrome","type":"exact"}],"termid":"MONDO:0005722","xrefs":{"Monarch":{"xref_id":"0005722"}}}


id: GO:1990113
data:
  {"annotated_genes":["SJAG_04012","SJAG_04093"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[80315,120098],"is_not":false,"summary":null,"term":"GO:1990113"}]},"cv_name":"biological_process","definition":"The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.","definition_xrefs":["PMID:23459708","GOC:rb"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein-containing complex assembly","termid":"GO:0065003"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04012":null,"SJAG_04093":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0065003"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0065003","GO:0044085","GO:0008150"],"is_obsolete":false,"name":"RNA polymerase I assembly","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"DNA-directed RNA polymerase I complex assembly","type":"exact"},{"name":"RNA Polymerase I complex assembly","type":"exact"}],"termid":"GO:1990113","terms_by_termid":{"GO:1990113":null}}


id: FYPO:0000144
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core).","definition_xrefs":["PomBase:mah","PomBase:vw"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal gene silencing","termid":"FYPO:0000574"},{"relation_name":"is_a","term_name":"abnormal negative regulation of transcription during vegetative growth","termid":"FYPO:0000624"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0001320","FYPO:0000002","FYPO:0001985","FYPO:0006551"],"is_obsolete":false,"name":"abnormal chromatin silencing","synonyms":[{"name":"abnormal chromatin silencing during mitotic cell cycle","type":"related"},{"name":"abnormal chromatin silencing during vegetative growth","type":"exact"}],"termid":"FYPO:0000144"}


id: PBO:0043599
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"collagen type XXVIII alpha 1 chain","termid":"PBO:0043599"}


id: PBO:0067435
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 556, pseudogene","termid":"PBO:0067435"}


id: GO:0033058
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Self-propelled movement of a cell or organism from one location to another along an axis.","definition_xrefs":["GOC:mtg_MIT_16mar07"],"direct_ancestors":[{"relation_name":"is_a","term_name":"locomotion","termid":"GO:0040011"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"directional locomotion","termid":"GO:0033058"}


id: PBO:0087833
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents","termid":"PBO:0087833"}


id: PBO:0091568
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial proton-transporting ATP synthase complex assembly protein","termid":"PBO:0091568"}


id: PBO:0031340
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_N-ethylmaleimide","termid":"PBO:0031340"}


id: GO:0050888
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The determination of where on the body surface, within the body or in the environment a stimulus originates.","definition_xrefs":["ISBN:0721619908"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sensory processing","termid":"GO:0050893"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"determination of stimulus location","termid":"GO:0050888"}


id: GO:0070588
data:
  {"annotated_genes":["SJAG_02019","SJAG_03399","SJAG_04668","SJAG_01090","SJAG_01400","SJAG_04471","SJAG_00296","SJAG_02322","SJAG_03631","SJAG_04028","SJAG_02532","SJAG_05229","SJAG_04096","SJAG_04757","SJAG_04551","SJAG_03850","SJAG_02877","SJAG_04698","SJAG_02440"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[67157,71272,74184,75279,80202,96729,97367,111362],"is_not":false,"summary":null,"term":"GO:0070588"},{"annotations":[99272],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0036444"},{"annotations":[94292,76221,116455,68214],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0098703"},{"annotations":[117586],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0140146"},{"annotations":[93087],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061856"},{"annotations":[93105,115372],"is_not":false,"rel_names":["regulates","negatively_regulates"],"summary":null,"term":"GO:1905949"},{"annotations":[104090],"is_not":false,"rel_names":["regulates","positively_regulates"],"summary":null,"term":"GO:1905665"},{"annotations":[110652],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0061454"}]},"cv_name":"biological_process","definition":"A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"calcium ion transport","termid":"GO:0006816"},{"relation_name":"is_a","term_name":"monoatomic cation transmembrane transport","termid":"GO:0098655"},{"relation_name":"is_a","term_name":"inorganic cation transmembrane transport","termid":"GO:0098662"}],"gene_count":19,"genes_by_uniquename":{"SJAG_00296":null,"SJAG_01090":null,"SJAG_01400":null,"SJAG_02019":null,"SJAG_02322":null,"SJAG_02440":null,"SJAG_02532":null,"SJAG_02877":null,"SJAG_03399":null,"SJAG_03631":null,"SJAG_03850":null,"SJAG_04028":null,"SJAG_04096":null,"SJAG_04471":null,"SJAG_04551":null,"SJAG_04668":null,"SJAG_04698":null,"SJAG_04757":null,"SJAG_05229":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006810"},{"rel_name":"is_a","termid":"GO:0055085"}],"interesting_parent_ids":["GO:0055085","GO:0008150","GO:0051179","GO:0006810"],"is_obsolete":false,"name":"calcium ion transmembrane transport","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000108":null},"secondary_identifiers":["Reactome:R-HSA-3295583"],"synonyms":[{"name":"calcium ion membrane transport","type":"exact"},{"name":"transmembrane calcium transport","type":"exact"}],"termid":"GO:0070588","terms_by_termid":{"GO:0036444":null,"GO:0061454":null,"GO:0061856":null,"GO:0070588":null,"GO:0098703":null,"GO:0140146":null,"GO:1905665":null,"GO:1905949":null}}


id: GO:0016934
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.","definition_xrefs":["GOC:mtg_transport","ISBN:0815340729"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inhibitory extracellular ligand-gated monoatomic ion channel activity","termid":"GO:0005237"},{"relation_name":"is_a","term_name":"chloride channel activity","termid":"GO:0005254"},{"relation_name":"is_a","term_name":"extracellularly glycine-gated ion channel activity","termid":"GO:0016933"},{"relation_name":"is_a","term_name":"ligand-gated monoatomic anion channel activity","termid":"GO:0099095"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0022857"},{"rel_name":"is_a","termid":"GO:0005215"}],"interesting_parent_ids":["GO:0005215","GO:0003674","GO:0022857"],"is_obsolete":false,"name":"extracellularly glycine-gated chloride channel activity","secondary_identifiers":["GO:0004891","Reactome:R-HSA-975389"],"synonyms":[{"name":"extracellular-glycine-gated chloride channel activity","type":"exact"},{"name":"glycine receptor","type":"broad"},{"name":"glycine-inhibited chloride channel activity","type":"related"}],"termid":"GO:0016934"}


id: FYPO:0005476
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of filamentous actin measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. The total actin level (globular and filamentous actin) may be normal or abnormal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased protein level during vegetative growth","termid":"FYPO:0001324"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0005447","FYPO:0006551","FYPO:0001320","FYPO:0001985"],"is_obsolete":false,"name":"decreased filamentous actin level","synonyms":[{"name":"decreased accumulation of filamentous actin in cell","type":"related"},{"name":"decreased cellular F-actin level","type":"exact"},{"name":"decreased cellular filamentous actin level","type":"exact"},{"name":"decreased filamentous actin level during mitotic cell cycle","type":"related"},{"name":"decreased filamentous actin level during vegetative growth","type":"exact"},{"name":"reduced filamentous actin level","type":"exact"}],"termid":"FYPO:0005476"}


id: PBO:0083036
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Delta(9) fatty acid desaturase; required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria","termid":"PBO:0083036"}


id: MONDO:0015952
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete genetic neurodegenerative disease (obsolete MONDO:0015952)","termid":"MONDO:0015952","xrefs":{"Monarch":{"xref_id":"0015952"}}}


id: PATO:0002098
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A disposition inhering in a tumour by virtue of the bearer's disposition to spread and invade distant tissues.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"is_a","term_name":"neoplastic","termid":"PATO:0002011"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neoplastic, metastatic","termid":"PATO:0002098"}


id: FYPO:0006341
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis does not occur in the equatorial region of the cell during mitosis as in wild-type cells.","definition_xrefs":["PomBase:mah","PMID:16141239"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal endocytosis during vegetative growth","termid":"FYPO:0000034"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000138"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000138","FYPO:0001985","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"abolished equatorial endocytosis during mitosis","synonyms":[{"name":"abolished endocytosis to cell division site","type":"related"},{"name":"abolished equatorial endocytosis during M phase of mitotic cell cycle","type":"related"},{"name":"abolished equatorial endocytosis during cell division","type":"related"},{"name":"abolished equatorial endocytosis during mitosis during vegetative growth","type":"exact"},{"name":"abolished equatorial endocytosis during mitotic M phase","type":"related"},{"name":"endocytosis restricted to cell end during mitosis","type":"related"},{"name":"equatorial endocytosis abolished during mitosis","type":"exact"}],"termid":"FYPO:0006341"}


id: MONDO:0019441
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare hereditary Transthyretin (TTR)-related systemic amyloidosis (ATTR) with predominant cardiac involvement resulting from myocardial infiltration of abnormal amyloid protein.","definition_xrefs":["Orphanet:85451"],"direct_ancestors":[{"relation_name":"is_a","term_name":"familial restrictive cardiomyopathy","termid":"MONDO:0016340"},{"relation_name":"is_a","term_name":"amyloidosis, hereditary systemic 1","termid":"MONDO:0971004"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0005267"},{"rel_name":"is_a","termid":"MONDO:0005244"},{"rel_name":"is_a","termid":"MONDO:0021179"}],"interesting_parent_ids":["MONDO:0005244","MONDO:0005267","MONDO:0005066","MONDO:0021179"],"is_obsolete":false,"name":"ATTRV122I amyloidosis","secondary_identifiers":["icd11.foundation:1449168185","ICD10EXP:I43.1*","SCTID:715655000","UMLS:C4275067","ICD10EXP:E85.4+","GARD:16755","MEDGEN:907865"],"synonyms":[{"name":"ATTRV122I-related amyloidosis","type":"exact"}],"termid":"MONDO:0019441","xrefs":{"Monarch":{"xref_id":"0019441"}}}


id: GO:1902965
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of protein localization to early endosome.","definition_xrefs":["PMID:22621900","GOC:TermGenie","GOC:sjp","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of protein localization to endosome","termid":"GO:1905666"},{"relation_name":"regulates","term_name":"protein localization to early endosome","termid":"GO:1902946"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of protein localization to early endosome","synonyms":[{"name":"regulation of protein localisation in early endosome","type":"exact"},{"name":"regulation of protein localisation to early endosome","type":"exact"},{"name":"regulation of protein localization in early endosome","type":"exact"}],"termid":"GO:1902965"}


id: PBO:0083482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TDP1","termid":"PBO:0083482"}


id: PATO:0001855
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A positional quality inhering in a bearer by virtue of the bearer's being in the plane of the horizon.","definition_xrefs":["thefreedictionary.com:thefreedictionary.com"],"direct_ancestors":[{"relation_name":"is_a","term_name":"position","termid":"PATO:0000140"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"horizontal","termid":"PATO:0001855"}


id: GO:1901147
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis.","definition_xrefs":["GOC:TermGenie","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesenchymal cell apoptotic process involved in metanephros development","termid":"GO:1900200"},{"relation_name":"is_a","term_name":"mesenchymal cell apoptotic process involved in nephron morphogenesis","termid":"GO:1901145"},{"relation_name":"part_of","term_name":"metanephric nephron morphogenesis","termid":"GO:0072273"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis","termid":"GO:1901147"}


id: FYPO:0000830
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of vanadate ions (VO4(3-)) than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased resistance to chemical during vegetative growth","termid":"FYPO:0000126"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002682"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0002682","FYPO:0000139","FYPO:0005447","FYPO:0000003"],"is_obsolete":false,"name":"resistance to vanadate","synonyms":[{"name":"normal growth on sodium orthovanadate","type":"exact"},{"name":"resistance to orthovanadate","type":"exact"},{"name":"resistance to sodium orthovanadate","type":"exact"},{"name":"resistance to vanadate during mitotic cell cycle","type":"related"},{"name":"resistance to vanadate during vegetative growth","type":"exact"},{"name":"resistance to vanadate ions","type":"exact"},{"name":"resistance to vanadate(3-)","type":"exact"},{"name":"resistance to vanadium oxoanion","type":"broad"},{"name":"resistant to vanadate","type":"exact"}],"termid":"FYPO:0000830"}


id: PBO:0000788
data:
  {"annotation_feature_type":"gene","cv_name":"EC numbers","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2.5.1.-","termid":"PBO:0000788"}


id: MONDO:0044247
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete palmomental reflex (obsolete MONDO:0044247)","secondary_identifiers":["OMIM:167700"],"synonyms":[{"name":"PALMOMENTAL reflex","type":"related"}],"termid":"MONDO:0044247","xrefs":{"Monarch":{"xref_id":"0044247"}}}


id: PBO:0089955
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"heterotrimeric G protein beta (WD repeat) subunit Git5","termid":"PBO:0089955"}


id: GO:0030978
data:
  {"annotated_genes":["SJAG_04666","SJAG_03057","SJAG_01028","SJAG_04236","SJAG_00610","SJAG_04184","SJAG_02278","SJAG_00424","SJAG_02916"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75291,72388,80560,75119,73177],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0070600"},{"annotations":[104796,91318,96850,94319],"is_not":false,"rel_names":["regulates"],"summary":null,"term":"GO:0070610"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"glucan metabolic process","termid":"GO:0044042"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00424":null,"SJAG_00610":null,"SJAG_01028":null,"SJAG_02278":null,"SJAG_02916":null,"SJAG_03057":null,"SJAG_04184":null,"SJAG_04236":null,"SJAG_04666":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0005975"}],"interesting_parent_ids":["GO:0005975","GO:0008150"],"is_obsolete":false,"name":"alpha-glucan metabolic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"alpha-glucan metabolism","type":"exact"}],"termid":"GO:0030978","terms_by_termid":{"GO:0070600":null,"GO:0070610":null}}


id: GO:0018326
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine.","definition_xrefs":["RESID:AA0056"],"gene_count":0,"genotype_count":0,"name":"obsolete enzyme active site formation via S-acetyl-L-cysteine (obsolete GO:0018326)","termid":"GO:0018326"}


id: PBO:0036274
data:
  {"annotation_feature_type":"gene","cv_name":"name_description","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Coiled-coil domain Telomerase Regulatory protein","termid":"PBO:0036274"}


id: PBO:0063400
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosducin like","termid":"PBO:0063400"}


id: GO:0044180
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a unicellular organism grows in a threadlike, filamentous shape.","definition_xrefs":["GOC:mtg_cambridge_2009"],"direct_ancestors":[{"relation_name":"is_a","term_name":"filamentous growth","termid":"GO:0030447"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"filamentous growth of a unicellular organism","termid":"GO:0044180"}


id: GO:0002941
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.","definition_xrefs":["PMID:10770586","PMID:9546370"],"direct_ancestors":[{"relation_name":"is_a","term_name":"epithelial cell proliferation","termid":"GO:0050673"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"synoviocyte proliferation","termid":"GO:0002941"}


id: PBO:0087041
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L1A; N-terminally acetylated; homologous to mammalian ribosomal protein L10A and bacterial L1; RPL1A has a paralog, RPL1B, that arose from the whole genome duplication; rpl1a rpl1b double null mutation is lethal; ribosomes containing Rpl1b are more efficient in translation of respiration-related proteins","termid":"PBO:0087041"}


id: GO:0004533
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.","definition_xrefs":["EC:3.1.13.2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"RNA exonuclease activity, producing 5'-phosphomonoesters","termid":"GO:0016896"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0004527"},{"rel_name":"is_a","termid":"GO:0140098"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0003824","GO:0004527","GO:0016788","GO:0140098"],"is_obsolete":false,"name":"exoribonuclease H activity","secondary_identifiers":["MetaCyc:3.1.13.2-RXN"],"synonyms":[{"name":"retroviral reverse transcriptase RNaseH","type":"related"}],"termid":"GO:0004533"}


id: PBO:0090834
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane thiamine/proton high affinity transmembrane transporter Thi9","termid":"PBO:0090834"}


id: PBO:0039086
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ATP/GTP binding carboxypeptidase 1","termid":"PBO:0039086"}


id: GO:0047965
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.","definition_xrefs":["MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN","EC:2.3.1.142"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-palmitoyltransferase activity","termid":"GO:0016416"},{"relation_name":"is_a","term_name":"catalytic activity, acting on a glycoprotein","termid":"GO:0140103"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0140096"},{"rel_name":"is_a","termid":"GO:0016746"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016740","GO:0140096","GO:0003674","GO:0016746","GO:0003824"],"is_obsolete":false,"name":"glycoprotein O-fatty-acyltransferase activity","synonyms":[{"name":"fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity","type":"related"},{"name":"protein acyltransferase activity","type":"related"}],"termid":"GO:0047965"}


id: PBO:0086622
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene","termid":"PBO:0086622"}


id: PBO:0003352
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human PPT1","termid":"PBO:0003352"}


id: GO:0042853
data:
  {"annotated_genes":["SJAG_04145"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[70212],"is_not":false,"summary":null,"term":"GO:0042853"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.","definition_xrefs":["GOC:mah","GOC:jl","GOC:jsg"],"direct_ancestors":[{"relation_name":"is_a","term_name":"alanine catabolic process","termid":"GO:0006524"},{"relation_name":"is_a","term_name":"pyruvate family amino acid catabolic process","termid":"GO:0009080"},{"relation_name":"is_a","term_name":"L-alanine metabolic process","termid":"GO:0042851"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04145":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0006520"}],"interesting_parent_ids":["GO:0044281","GO:0008150","GO:0006520"],"is_obsolete":false,"name":"L-alanine catabolic process","references_by_uniquename":{"GO_REF:0000041":null},"synonyms":[{"name":"L-alanine breakdown","type":"exact"},{"name":"L-alanine catabolism","type":"exact"},{"name":"L-alanine degradation","type":"exact"}],"termid":"GO:0042853","terms_by_termid":{"GO:0042853":null}}


id: MONDO:0030062
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"familial isolated arrhythmogenic right ventricular dysplasia","termid":"MONDO:0016342"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005267"}],"interesting_parent_ids":["MONDO:0005267"],"is_obsolete":false,"name":"arrhythmogenic right ventricular dysplasia, familial, 14","secondary_identifiers":["OMIM:618920","UMLS:C5394505","DOID:0080959","MEDGEN:1712001"],"synonyms":[{"name":"ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA, FAMILIAL, 14","type":"exact"},{"name":"ARVD14","type":"exact"},{"name":"Arrhythmogenic Right Ventricular Cardiomyopathy 14","type":"exact"},{"name":"arrhythmogenic right ventricular dysplasia, familial, 14","type":"exact"}],"termid":"MONDO:0030062","xrefs":{"Monarch":{"xref_id":"0030062"}}}


id: GO:0044440
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"OBSOLETE. Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered.","definition_xrefs":["PMID:19696797","GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete endosomal part (obsolete GO:0044440)","synonyms":[{"name":"endosomal subcomponent","type":"exact"},{"name":"endosome component","type":"exact"}],"termid":"GO:0044440"}


id: PBO:0088961
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"serine/threonine protein phosphatase PP2A regulatory subunit, PTPA family Ypa1","termid":"PBO:0088961"}


id: PBO:0062888
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ovo like transcriptional repressor 1","termid":"PBO:0062888"}


id: GO:0097707
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes.","definition_xrefs":["PMID:25236395","PMID:26794443","GOC:mtg_apoptosis"],"direct_ancestors":[{"relation_name":"is_a","term_name":"programmed cell death","termid":"GO:0012501"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"ferroptosis","synonyms":[{"name":"iron-dependent programmed cell death","type":"related"}],"termid":"GO:0097707"}


id: GO:1904201
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of iodide transport.","definition_xrefs":["GOC:TermGenie","PMID:20392814","GO_REF:0000058"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of monoatomic anion transport","termid":"GO:0044070"},{"relation_name":"regulates","term_name":"iodide transport","termid":"GO:0015705"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0006810"}],"interesting_parent_ids":["GO:0008150","GO:0006810"],"is_obsolete":false,"name":"regulation of iodide transport","termid":"GO:1904201"}


id: MONDO:0014268
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Combined immunodeficiency due to OX40 deficiency is a rare combined T and B cell immunodeficiency characterized by susceptibility to develop an aggressive, childhood-onset, disseminated, cutaneous and systemic Kaposi sarcoma.","definition_xrefs":["Orphanet:431149"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"hereditary neoplastic syndrome","termid":"MONDO:0015356"},{"relation_name":"excluded_subClassOf","term_name":"non-SCID combined immunodeficiency","termid":"MONDO:0018814"},{"relation_name":"is_a","term_name":"combined immunodeficiency","termid":"MONDO:0015131"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005046"}],"interesting_parent_ids":["MONDO:0005046"],"is_obsolete":false,"name":"combined immunodeficiency due to OX40 deficiency","secondary_identifiers":["DOID:0111935","OMIM:615593","MEDGEN:816383","SCTID:766879006","GARD:17710","UMLS:C3810053"],"synonyms":[{"name":"IMD16","type":"related"},{"name":"OX40 deficiency","type":"related"},{"name":"combined immunodeficiency with childhood-onset Kaposi sarcoma","type":"exact"},{"name":"combined immunodeficiency with impaired immunity to HHV-8","type":"exact"},{"name":"combined immunodeficiency with impaired immunity to human herpes virus 8","type":"exact"},{"name":"immunodeficiency 16","type":"related"},{"name":"immunodeficiency type 16","type":"exact"}],"termid":"MONDO:0014268","xrefs":{"Monarch":{"xref_id":"0014268"}}}


id: PBO:0065375
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pregnancy specific beta-1-glycoprotein 3","termid":"PBO:0065375"}


id: PBO:0041623
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"calcium binding tyrosine phosphorylation regulated","termid":"PBO:0041623"}


id: PATO:0001927
data:
  {"annotation_feature_type":"gene","cv_name":"quality","definition":"A fluorescence which is lower than normal.","definition_xrefs":["PATOC:GVG"],"direct_ancestors":[{"relation_name":"decreased_in_magnitude_relative_to","term_name":"normal","termid":"PATO:0000461"},{"relation_name":"is_a","term_name":"fluorescent","termid":"PATO:0001290"},{"relation_name":"is_a","term_name":"decreased object quality","termid":"PATO:0002303"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"decreased fluorescence","synonyms":[{"name":"low fluorescence","type":"exact"}],"termid":"PATO:0001927"}


id: GO:0002161
data:
  {"annotated_genes":["SJAG_00443","SJAG_01259","SJAG_03545","SJAG_01248","SJAG_04738","SJAG_02428","SJAG_04285","SJAG_02015","SJAG_01797"],"annotation_feature_type":"gene","cv_annotations":{"molecular_function":[{"annotations":[57075,57383,59164,64437,65223,68269,77651],"is_not":false,"summary":null,"term":"GO:0002161"},{"annotations":[107893],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0043907"},{"annotations":[75348],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0051500"},{"annotations":[102388],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0106026"}]},"cv_name":"molecular_function","definition":"The hydrolysis of an incorrectly aminoacylated tRNA.","definition_xrefs":["PMID:16087889","GOC:hjd","PMID:14663147"],"direct_ancestors":[{"relation_name":"is_a","term_name":"catalytic activity, acting on a tRNA","termid":"GO:0140101"}],"gene_count":9,"genes_by_uniquename":{"SJAG_00443":null,"SJAG_01248":null,"SJAG_01259":null,"SJAG_01797":null,"SJAG_02015":null,"SJAG_02428":null,"SJAG_03545":null,"SJAG_04285":null,"SJAG_04738":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0140101"},{"rel_name":"is_a","termid":"GO:0140098"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0140101","GO:0140098"],"is_obsolete":false,"name":"aminoacyl-tRNA deacylase activity","references_by_uniquename":{"GO_REF:0000002":null,"GO_REF:0000033":null,"GO_REF:0000107":null},"synonyms":[{"name":"amino acid proofreading activity","type":"related"},{"name":"aminoacyl-tRNA hydrolysis activity","type":"related"}],"termid":"GO:0002161","terms_by_termid":{"GO:0002161":null,"GO:0043907":null,"GO:0051500":null,"GO:0106026":null}}


id: GO:0044683
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.","definition_xrefs":["MetaCyc:RXN-8125","PMID:9371433"],"direct_ancestors":[{"relation_name":"is_a","term_name":"methyltransferase activity","termid":"GO:0008168"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016741"}],"interesting_parent_ids":["GO:0003674","GO:0016741","GO:0016740","GO:0003824"],"is_obsolete":false,"name":"methylthiol:coenzyme M methyltransferase activity","secondary_identifiers":["RHEA:32667","EC:2.1.1.251"],"synonyms":[{"name":"methylthiol:coenzyme M methyl transferase activity","type":"exact"}],"termid":"GO:0044683"}


id: FYPO:0007842
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is absent.","definition_xrefs":["PomBase:mah","PMID:34019809"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abolished catalytic activity","termid":"FYPO:0000664"},{"relation_name":"is_a","term_name":"abnormal peptide alpha-N-acetyltransferase activity","termid":"FYPO:0007839"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000661"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000707"},{"rel_name":"is_a","termid":"FYPO:0000654"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000654","FYPO:0001985","FYPO:0000707","FYPO:0000661"],"is_obsolete":false,"name":"abolished peptide alpha-N-acetyltransferase activity","synonyms":[{"name":"abolished NAT activity","type":"related"},{"name":"abolished protein N-terminal acetyltransferase activity","type":"exact"},{"name":"peptide alpha-N-acetyltransferase activity abolished","type":"exact"}],"termid":"FYPO:0007842"}


id: FYPO:0003920
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal replication fork arrest at mating-type locus","termid":"FYPO:0003083"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000293"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0001985","FYPO:0005447","FYPO:0000293"],"is_obsolete":false,"name":"increased replication fork arrest at mating-type locus","synonyms":[{"name":"increased replication fork arrest at mating-type locus during mitotic cell cycle","type":"related"},{"name":"increased replication fork arrest at mating-type locus during vegetative growth","type":"exact"}],"termid":"FYPO:0003920"}


id: PBO:0030193
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-elongated_multinucleate_aseptate_vegetative_cell","termid":"PBO:0030193"}


id: PBO:0031722
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-normal_meiotic_recombination","termid":"PBO:0031722"}


id: GO:0050742
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine.","definition_xrefs":["RESID:AA0351"],"gene_count":0,"genotype_count":0,"name":"obsolete protein-FMN linkage via S-(4a-FMN)-L-cysteine (obsolete GO:0050742)","termid":"GO:0050742"}


id: GO:0036464
data:
  {"annotated_genes":["SJAG_03132","SJAG_00686","SJAG_01159","SJAG_16457","SJAG_04772","SJAG_03762","SJAG_01822","SJAG_03498","SJAG_03954","SJAG_01222","SJAG_02592","SJAG_01625","SJAG_04427","SJAG_01548","SJAG_03276","SJAG_04342","SJAG_02638","SJAG_03283","SJAG_03696","SJAG_01512","SJAG_03460","SJAG_02263","SJAG_01436","SJAG_04640","SJAG_03214","SJAG_04480","SJAG_03876","SJAG_03070","SJAG_00544","SJAG_00759","SJAG_02419","SJAG_03597","SJAG_02573","SJAG_01479","SJAG_01053","SJAG_00391","SJAG_16454","SJAG_01910","SJAG_02239","SJAG_04407","SJAG_05010","SJAG_01897","SJAG_02164","SJAG_02213","SJAG_03113","SJAG_00507","SJAG_03424","SJAG_02628","SJAG_02663","SJAG_00423","SJAG_01650","SJAG_05694","SJAG_04744","SJAG_03157","SJAG_04672","SJAG_01026","SJAG_04880","SJAG_04350","SJAG_02995","SJAG_03023","SJAG_02469","SJAG_01317","SJAG_02808","SJAG_00474","SJAG_03277","SJAG_00285","SJAG_00966","SJAG_02540","SJAG_01954"],"annotation_feature_type":"gene","cv_annotations":{"cellular_component":[{"annotations":[96692,81148,94442,101861,93439,94903,107632,74784,107633,90225,96459,108911,111871,91778,100851,115332,91574,96258,113071,92187,99029,92069,107539,119312,89380,76398,92145,57668,72365,60525,111973,115630,94902,68400,91031,74349,75901,99708,78543,80570,91362,96458,97997,107279],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010494"},{"annotations":[101863,117165,111874,118628,76368,81500,73467,81434,80580,71997,77255,77809,75445,80679,78542,79349,91576,74908,76010,72864,77574,78392,114888,76174,79491,81408,74492,80584,71684,71708,92190,79568,81537,81774,97502],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0000932"}]},"cv_name":"cellular_component","definition":"A ribonucleoprotein granule located in the cytoplasm.","definition_xrefs":["GOC:bf","PMID:15121898","GOC:PARL"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribonucleoprotein granule","termid":"GO:0035770"},{"relation_name":"part_of","term_name":"cytoplasm","termid":"GO:0005737"}],"gene_count":69,"genes_by_uniquename":{"SJAG_00285":null,"SJAG_00391":null,"SJAG_00423":null,"SJAG_00474":null,"SJAG_00507":null,"SJAG_00544":null,"SJAG_00686":null,"SJAG_00759":null,"SJAG_00966":null,"SJAG_01026":null,"SJAG_01053":null,"SJAG_01159":null,"SJAG_01222":null,"SJAG_01317":null,"SJAG_01436":null,"SJAG_01479":null,"SJAG_01512":null,"SJAG_01548":null,"SJAG_01625":null,"SJAG_01650":null,"SJAG_01822":null,"SJAG_01897":null,"SJAG_01910":null,"SJAG_01954":null,"SJAG_02164":null,"SJAG_02213":null,"SJAG_02239":null,"SJAG_02263":null,"SJAG_02419":null,"SJAG_02469":null,"SJAG_02540":null,"SJAG_02573":null,"SJAG_02592":null,"SJAG_02628":null,"SJAG_02638":null,"SJAG_02663":null,"SJAG_02808":null,"SJAG_02995":null,"SJAG_03023":null,"SJAG_03070":null,"SJAG_03113":null,"SJAG_03132":null,"SJAG_03157":null,"SJAG_03214":null,"SJAG_03276":null,"SJAG_03277":null,"SJAG_03283":null,"SJAG_03424":null,"SJAG_03460":null,"SJAG_03498":null,"SJAG_03597":null,"SJAG_03696":null,"SJAG_03762":null,"SJAG_03876":null,"SJAG_03954":null,"SJAG_04342":null,"SJAG_04350":null,"SJAG_04407":null,"SJAG_04427":null,"SJAG_04480":null,"SJAG_04640":null,"SJAG_04672":null,"SJAG_04744":null,"SJAG_04772":null,"SJAG_04880":null,"SJAG_05010":null,"SJAG_05694":null,"SJAG_16454":null,"SJAG_16457":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005737","GO:0005575"],"is_obsolete":false,"name":"cytoplasmic ribonucleoprotein granule","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"synonyms":[{"name":"Staufen granule","type":"narrow"}],"termid":"GO:0036464","terms_by_termid":{"GO:0000932":null,"GO:0010494":null}}


id: GO:0007618
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.","definition_xrefs":["GOC:jl","ISBN:0387520546"],"direct_ancestors":[{"relation_name":"is_a","term_name":"multi-organism reproductive process","termid":"GO:0044703"},{"relation_name":"part_of","term_name":"sexual reproduction","termid":"GO:0019953"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mating","termid":"GO:0007618"}


id: PBO:0066633
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Rab interacting lysosomal protein like 2","termid":"PBO:0066633"}


id: GO:0007509
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.","definition_xrefs":["GOC:sat","GOC:isa_complete"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mesodermal cell migration","termid":"GO:0008078"},{"relation_name":"is_a","term_name":"cell migration involved in gastrulation","termid":"GO:0042074"},{"relation_name":"is_a","term_name":"tissue migration","termid":"GO:0090130"},{"relation_name":"part_of","term_name":"mesoderm formation","termid":"GO:0001707"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mesoderm migration involved in gastrulation","termid":"GO:0007509"}


id: PBO:0080832
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"YAP1 pseudogene 3","termid":"PBO:0080832"}


id: MOD:00186
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively substitutes an L-tyrosine residue with 3',3'',5'-triiodo-L-thyronine.","definition_xrefs":["ChEBI:18258","DeltaMass:0","Unimod:397","RESID:AA0177"],"direct_ancestors":[{"relation_name":"is_a","term_name":"triiodinated residue","termid":"MOD:00502"},{"relation_name":"is_a","term_name":"iodinated tyrosine","termid":"MOD:00998"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"3',3'',5'-triiodo-L-thyronine","synonyms":[{"name":"(S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid","type":"exact"},{"name":"3',3'',5'-triiodo-L-thyronine","type":"exact"},{"name":"3,3',5-triiodo-L-thyronine","type":"exact"},{"name":"3,5,3'-Triiodothyronine (from Tyrosine)","type":"exact"},{"name":"3,5,3'-triiodo-L-thyronine","type":"exact"},{"name":"4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine","type":"exact"},{"name":"I3Thy","type":"exact"},{"name":"MOD_RES Triiodothyronine","type":"exact"},{"name":"O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine","type":"exact"},{"name":"T3","type":"exact"},{"name":"Triiodothyronine","type":"related"},{"name":"liothyronine","type":"exact"},{"name":"triiodo","type":"related"}],"termid":"MOD:00186"}


id: GO:0098633
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Binding to a collagen fibril.","definition_xrefs":["PMID:21421911","GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"extracellular matrix binding","termid":"GO:0050840"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005488"},{"rel_name":"is_a","termid":"GO:0003674"}],"interesting_parent_ids":["GO:0005488","GO:0003674"],"is_obsolete":false,"name":"collagen fibril binding","termid":"GO:0098633"}


id: GO:0021615
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.","definition_xrefs":["ISBN:0838580343","GOC:cls","GO_REF:0000021","GOC:dgh","GOC:dph","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cranial nerve morphogenesis","termid":"GO:0021602"},{"relation_name":"part_of","term_name":"glossopharyngeal nerve development","termid":"GO:0021563"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"glossopharyngeal nerve morphogenesis","synonyms":[{"name":"CN IX morphogenesis","type":"related"}],"termid":"GO:0021615"}


id: MOD:01162
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from Unimod N-linked glycosylation","definition_xrefs":["Unimod:308"],"direct_ancestors":[{"relation_name":"is_a","term_name":"complex glycosylation","termid":"MOD:00725"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MOD:00764"}],"interesting_parent_ids":["MOD:00764"],"is_obsolete":false,"name":"fucosylated biantennary","synonyms":[{"name":"Fucosylated biantennary","type":"related"},{"name":"dHex(1)Hex(5)HexNAc(4)","type":"related"}],"termid":"MOD:01162"}


id: GO:0002937
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.","definition_xrefs":["ISBN:155581073X"],"direct_ancestors":[{"relation_name":"is_a","term_name":"tRNA thio-modification","termid":"GO:0034227"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006399"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006399","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"tRNA 4-thiouridine biosynthesis","termid":"GO:0002937"}


id: PBO:0004628
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribonucleotide reductase small subunit Suc22","termid":"PBO:0004628"}


id: GO:0071415
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to purine-containing compound","termid":"GO:0014074"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cellular response to purine-containing compound","synonyms":[{"name":"cellular response to purine","type":"related"}],"termid":"GO:0071415"}


id: GO:1990376
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation that results in negative regulation of mitotic G1/S transition.","definition_xrefs":["PMID:9135083"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation (obsolete GO:1990376)","termid":"GO:1990376"}


id: GO:0048232
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.","definition_xrefs":["GOC:dph","GOC:jid"],"direct_ancestors":[{"relation_name":"is_a","term_name":"gamete generation","termid":"GO:0007276"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"male gamete generation","termid":"GO:0048232"}


id: GO:0034016
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.","definition_xrefs":["RHEA:14889"],"direct_ancestors":[{"relation_name":"is_a","term_name":"intramolecular oxidoreductase activity, transposing C=C bonds","termid":"GO:0016863"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016853"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003824","GO:0016853","GO:0003674"],"is_obsolete":false,"name":"polyenoic fatty acid isomerase activity","secondary_identifiers":["EC:5.3.3.13","MetaCyc:5.3.3.13-RXN","KEGG_REACTION:R06502"],"synonyms":[{"name":"(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity","type":"related"},{"name":"(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity","type":"related"},{"name":"(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity","type":"related"},{"name":"PFI","type":"related"},{"name":"eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity","type":"related"}],"termid":"GO:0034016"}


id: GO:0047185
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.","definition_xrefs":["EC:2.3.1.44","RHEA:18305"],"direct_ancestors":[{"relation_name":"is_a","term_name":"O-acetyltransferase activity","termid":"GO:0016413"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016740"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016746"}],"interesting_parent_ids":["GO:0016740","GO:0003674","GO:0003824","GO:0016746"],"is_obsolete":false,"name":"N-acetylneuraminate 4-O-acetyltransferase activity","secondary_identifiers":["MetaCyc:2.3.1.44-RXN","KEGG_REACTION:R01806"],"synonyms":[{"name":"acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity","type":"related"},{"name":"sialate O-acetyltransferase","type":"broad"}],"termid":"GO:0047185"}


id: MONDO:1010343
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Diabetic cataract that occurs in non-human animals.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cataract, non-human animal","termid":"MONDO:1012962"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"diabetic cataract, non-human animal","secondary_identifiers":["OMIA:001865"],"termid":"MONDO:1010343","xrefs":{"Monarch":{"xref_id":"1010343"}}}


id: FYPO:0005308
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 occurs to a greater extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased histone acetylation during vegetative growth","termid":"FYPO:0000332"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0002274"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0002494"}],"interesting_parent_ids":["FYPO:0002274","FYPO:0002494","FYPO:0005447","FYPO:0000002","FYPO:0001985","FYPO:0001320"],"is_obsolete":false,"name":"increased histone H4-K8 acetylation during vegetative growth","synonyms":[{"name":"increased histone H4-K8 acetylation during mitotic cell cycle","type":"related"},{"name":"increased histone H4K8 acetylation during vegetative growth","type":"exact"}],"termid":"FYPO:0005308"}


id: FYPO:0006438
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which DNA molecules corresponding to alkylation damage repair intermediates are absent from the cell during DNA replication.","definition_xrefs":["PomBase:mah","PMID:23071723"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal vegetative cell phenotype","termid":"FYPO:0003755"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"alkylation damage repair intermediates absent","synonyms":[{"name":"alkylation damage repair intermediates absent during mitotic cell cycle","type":"related"},{"name":"alkylation damage repair intermediates absent during vegetative growth","type":"exact"}],"termid":"FYPO:0006438"}


id: GO:0016201
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.","definition_xrefs":["ISBN:0878932437","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative chemotaxis","termid":"GO:0050919"},{"relation_name":"part_of","term_name":"synaptic target recognition","termid":"GO:0008039"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"synaptic target inhibition","termid":"GO:0016201"}


id: FYPO:0005845
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a lower extent than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased histone H3-K9 trimethylation during vegetative growth","termid":"FYPO:0000882"},{"relation_name":"is_a","term_name":"abnormal histone methylation at silent mating-type cassette during vegetative growth","termid":"FYPO:0007373"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0002494"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0002274"}],"interesting_parent_ids":["FYPO:0005447","FYPO:0002274","FYPO:0000002","FYPO:0001985","FYPO:0002494","FYPO:0001320"],"is_obsolete":false,"name":"decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth","synonyms":[{"name":"decreased histone H3 K9 trimethylation at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"decreased histone H3-K9 trimethylation at mating-type region heterochromatin during vegetative growth","type":"exact"},{"name":"decreased histone H3-K9 trimethylation at silent mating-type cassette during mitotic cell cycle","type":"related"},{"name":"decreased histone H3K9 trimethylation at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"decreased histone H3K9me3 at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"decreased histone lysine H3 K9 trimethylation at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"decreased silent mating-type cassette histone H3-K9 trimethylation during vegetative growth","type":"exact"},{"name":"reduced histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth","type":"exact"}],"termid":"FYPO:0005845"}


id: MONDO:0021205
data:
  {"annotated_genes":["SJAG_04755","SJAG_05313"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89038,89039],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"MONDO:0968980"}]},"cv_name":"mondo","definition":"A disease that involves the ear.","definition_xrefs":["MONDO:patterns/location"],"direct_ancestors":[{"relation_name":"is_a","term_name":"otorhinolaryngologic disease","termid":"MONDO:0024623"}],"gene_count":2,"genes_by_uniquename":{"SJAG_04755":null,"SJAG_05313":null},"genotype_count":0,"is_obsolete":false,"name":"disorder of ear","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:3946","NCIT:C26757","SCTID:25906001","UMLS:C0013447","ICD9:388.8","ICD9:388.9"],"synonyms":[{"name":"Ear disease","type":"exact"},{"name":"Ear disorder","type":"exact"},{"name":"disease of ear","type":"exact"},{"name":"disease or disorder of ear","type":"exact"},{"name":"disorder of ear","type":"exact"},{"name":"ear disease","type":"exact"},{"name":"ear disease or disorder","type":"exact"}],"termid":"MONDO:0021205","terms_by_termid":{"MONDO:0968980":null},"xrefs":{"Monarch":{"xref_id":"0021205"}}}


id: MOD:00920
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that modifies an L-valine residue.","definition_xrefs":["PubMed:18688235"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein modification categorized by amino acid modified","termid":"MOD:01157"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"modified L-valine residue","synonyms":[{"name":"ModVal","type":"exact"}],"termid":"MOD:00920"}


id: PBO:0070594
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ribosomal protein L7a pseudogene 61","termid":"PBO:0070594"}


id: MONDO:0859205
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"female reproductive system disorder","termid":"MONDO:0002263"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"delayed puberty, self-limited","secondary_identifiers":["UMLS:C2874202","OMIM:619613","MEDGEN:1789612"],"termid":"MONDO:0859205","xrefs":{"Monarch":{"xref_id":"0859205"}}}


id: MONDO:0035651
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome is an autosomal dominant disorder characterized by choanal atresia, athelia or hypoplastic nipples, branchial sinus abnormalities, neck pits, lacrimal duct anomalies, hearing loss, external ear malformations, and thyroid abnormalities.","definition_xrefs":["OMIM:620186"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome","secondary_identifiers":["MEDGEN:1830104","GARD:22366","Orphanet:589856","UMLS:C5680310"],"synonyms":[{"name":"BCAHH","type":"exact"},{"name":"KMT2D-related choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome","type":"exact"},{"name":"branchial arch abnormalities, choanal atresia, athelia, hearing loss, and hypothyroidism syndrome","type":"exact"}],"termid":"MONDO:0035651","xrefs":{"Monarch":{"xref_id":"0035651"}}}


id: FYPO:0001480
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal catalytic activity","termid":"FYPO:0000660"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000652"},{"rel_name":"is_a","termid":"FYPO:0000654"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000652","FYPO:0000257","FYPO:0000654"],"is_obsolete":false,"name":"normal alpha,alpha-trehalase activity","synonyms":[{"name":"normal neutral trehalase activity","type":"exact"},{"name":"normal trehalase activity","type":"broad"}],"termid":"FYPO:0001480"}


id: PBO:0064085
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phosphatidylinositol transfer protein alpha","termid":"PBO:0064085"}


id: FYPO:0006570
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair is normal (i.e. indistinguishable from wild type). UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).","definition_xrefs":["PomBase:mah","GO:0070914"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal DNA repair","termid":"FYPO:0006569"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000298"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001312","FYPO:0000257","FYPO:0000298","FYPO:0001320"],"is_obsolete":false,"name":"normal UV-damage excision repair","synonyms":[{"name":"normal UV-damage excision repair during mitotic cell cycle","type":"related"},{"name":"normal UV-damage excision repair during vegetative growth","type":"exact"}],"termid":"FYPO:0006570"}


id: MONDO:0014744
data:
  {"annotated_genes":["SJAG_04622"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87722],"is_not":false,"summary":null,"term":"MONDO:0014744"}]},"cv_name":"mondo","definition":"An autosomal recessive cerebellar ataxia that has material basis in homozygous or compound heterozygous mutation in the SCYL1 gene on chromosome 11q13.","definition_xrefs":["DOID:0111155"],"direct_ancestors":[{"relation_name":"is_a","term_name":"syndromic disease","termid":"MONDO:0002254"},{"relation_name":"is_a","term_name":"autosomal recessive syndromic cerebellar ataxia","termid":"MONDO:0020047"},{"relation_name":"is_a","term_name":"acute disease","termid":"MONDO:0020683"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04622":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0006025"},{"rel_name":"is_a","termid":"MONDO:0005559"}],"interesting_parent_ids":["MONDO:0006025","MONDO:0005559"],"is_obsolete":false,"name":"acute infantile liver failure-cerebellar ataxia-peripheral sensory motor neuropathy syndrome","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["OMIM:616719","Orphanet:466794","GARD:17833","MEDGEN:1800507","UMLS:C5569084"],"synonyms":[{"name":"SCAR21","type":"exact"},{"name":"acute infantile liver failure-cerebellar ataxia-peripheral sensory motor neuropathy syndrome","type":"exact"},{"name":"autosomal recessive spinocerebellar ataxia 21","type":"related"},{"name":"autosomal recessive spinocerebellar ataxia 21 with hepatopathy","type":"exact"},{"name":"autosomal recessive spinocerebellar ataxia type 21","type":"exact"},{"name":"spinocerebellar ataxia, autosomal recessive 21","type":"exact"},{"name":"spinocerebellar ataxia, autosomal recessive 21, with hepatopathy","type":"related"},{"name":"spinocerebellar ataxia, autosomal recessive type 21","type":"exact"}],"termid":"MONDO:0014744","terms_by_termid":{"MONDO:0014744":null},"xrefs":{"Monarch":{"xref_id":"0014744"}}}


id: MONDO:0004544
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A WHO grade II, usually recurring meningioma characterized by the predominance of tissues that are histologically similar to chordoma.","definition_xrefs":["NCIT:C6908"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"clear cell meningioma","termid":"MONDO:0002918"},{"relation_name":"is_a","term_name":"grade II meningioma","termid":"MONDO:0045056"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"chordoid meningioma","secondary_identifiers":["MEDGEN:235089","ONCOTREE:CHOM","DOID:8368","UMLS:C1370510"],"synonyms":[{"name":"CHOM","type":"related"},{"name":"chordoid meningioma","type":"exact"},{"name":"meningioma, chordoid","type":"exact"},{"name":"meningioma, chordoid (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0004544","xrefs":{"Monarch":{"xref_id":"0004544"}}}


id: PBO:0070330
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNY4 pseudogene 2","termid":"PBO:0070330"}


id: PBO:0052451
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Kruppel like factor 3 pseudogene 2","termid":"PBO:0052451"}


id: MOD:01345
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"A protein modification that effectively converts an L-threonine residue to 2-amino-3-oxobutanoic acid.","definition_xrefs":["OMSSA:23","Unimod:401#T","PubMed:12716131","PubMed:9252331"],"direct_ancestors":[{"relation_name":"is_a","term_name":"modified L-threonine residue","termid":"MOD:00917"},{"relation_name":"is_a","term_name":"didehydrogenated residue","termid":"MOD:01888"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2-amino-3-oxobutanoic acid","synonyms":[{"name":"3-ketobutyrine","type":"exact"},{"name":"Didehydro","type":"related"},{"name":"twoamino3oxobutanoicacid","type":"exact"},{"name":"2-amino-3-ketobutyric acid","type":"exact"},{"name":"2-amino-3-oxo-butanoic_acid","type":"related"}],"termid":"MOD:01345"}


id: PBO:0119826
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mitochondrial ribosome recycling factor Rrf1","termid":"PBO:0119826"}


id: MONDO:0014982
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Any myopia (disease) in which the cause of the disease is a mutation in the P4HA2 gene.","definition_xrefs":["MONDO:patterns/disease_series_by_gene"],"direct_ancestors":[{"relation_name":"is_a","term_name":"myopia","termid":"MONDO:0001384"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"myopia 25, autosomal dominant","secondary_identifiers":["OMIM:617238","UMLS:C4310655","MEDGEN:934622"],"synonyms":[{"name":"MYP25","type":"exact"},{"name":"P4HA2 myopia (disease)","type":"exact"},{"name":"myopia (disease) caused by mutation in P4HA2","type":"exact"},{"name":"myopia 25, autosomal dominant","type":"exact"},{"name":"myopia 25, autosomal dominant; MYP25","type":"exact"}],"termid":"MONDO:0014982","xrefs":{"Monarch":{"xref_id":"0014982"}}}


id: MONDO:0019786
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Severe intellectual disability-epilepsy-anal anomalies-distal phalangeal hypoplasia is characterized by severe intellectual deficit, epilepsy, hypoplasia of the terminal phalanges, and an anteriorly displaced anus. It has been described in two sisters born to consanguineous parents. The syndrome is transmitted as an autosomal recessive trait and appears to be caused by anomalies in to chromosome regions, one localized to chromosome 1 and the other to chromosome 14.","definition_xrefs":["Orphanet:94066"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"syndromic intellectual disability","termid":"MONDO:0000508"},{"relation_name":"is_a","term_name":"multiple congenital anomalies/dysmorphic syndrome-intellectual disability","termid":"MONDO:0015159"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"severe intellectual disability-epilepsy-anal anomalies-distal phalangeal hypoplasia","secondary_identifiers":["MEDGEN:1372948","UMLS:C4510007","GARD:19247"],"termid":"MONDO:0019786","xrefs":{"Monarch":{"xref_id":"0019786"}}}


id: GO:0047714
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 a fatty acid + 2 H+.","definition_xrefs":["RHEA:13189"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lipase activity","termid":"GO:0016298"},{"relation_name":"is_a","term_name":"carboxylic ester hydrolase activity","termid":"GO:0052689"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016788"},{"rel_name":"is_a","termid":"GO:0016787"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0016787","GO:0003674","GO:0016788","GO:0003824"],"is_obsolete":false,"name":"galactolipase activity","secondary_identifiers":["MetaCyc:GALACTOLIPASE-RXN","EC:3.1.1.26"],"synonyms":[{"name":"1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity","type":"related"},{"name":"galactolipid acylhydrolase activity","type":"related"},{"name":"galactolipid lipase activity","type":"related"},{"name":"polygalactolipase activity","type":"related"}],"termid":"GO:0047714"}


id: PBO:0048955
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GOT2 pseudogene 6","termid":"PBO:0048955"}


id: GO:0050025
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2.","definition_xrefs":["RHEA:20728"],"direct_ancestors":[{"relation_name":"is_a","term_name":"L-amino-acid oxidase activity","termid":"GO:0001716"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"L-glutamate oxidase activity","secondary_identifiers":["EC:1.4.3.11","MetaCyc:L-GLUTAMATE-OXIDASE-RXN"],"synonyms":[{"name":"L-glutamate:oxygen oxidoreductase (deaminating)","type":"related"},{"name":"L-glutamic acid oxidase activity","type":"related"},{"name":"glutamate (acceptor) dehydrogenase activity","type":"related"},{"name":"glutamate oxidase activity","type":"related"},{"name":"glutamic acid oxidase activity","type":"related"},{"name":"glutamic dehydrogenase (acceptor)","type":"related"}],"termid":"GO:0050025"}


id: MONDO:0032752
data:
  {"annotated_genes":["SJAG_02236"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[88994],"is_not":false,"summary":null,"term":"MONDO:0032752"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"developmental and epileptic encephalopathy","termid":"MONDO:0100062"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02236":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0700092"},{"rel_name":"is_a","termid":"MONDO:0005027"}],"interesting_parent_ids":["MONDO:0005027","MONDO:0700092"],"is_obsolete":false,"name":"developmental and epileptic encephalopathy, 75","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["GARD:16352","MEDGEN:1684253","OMIM:618437","UMLS:C5193099","DOID:0112211"],"synonyms":[{"name":"DEE75","type":"exact"},{"name":"EIEE75","type":"exact"},{"name":"EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 75","type":"exact"},{"name":"developmental and epileptic encephalopathy 75","type":"exact"},{"name":"epileptic encephalopathy, early infantile, 75","type":"exact"}],"termid":"MONDO:0032752","terms_by_termid":{"MONDO:0032752":null},"xrefs":{"Monarch":{"xref_id":"0032752"}}}


id: PR:O74564
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- wtf9 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O74564"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized protein wtf9 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC970.11c","synonyms":[{"name":"Spom972h-wtf9","type":"exact"}],"termid":"PR:O74564"}


id: GO:0070428
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.","definition_xrefs":["GOC:add"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","termid":"GO:0070424"},{"relation_name":"regulates","term_name":"nucleotide-binding oligomerization domain containing 1 signaling pathway","termid":"GO:0070427"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway","synonyms":[{"name":"regulation of NOD1 signaling pathway","type":"exact"},{"name":"regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway","type":"exact"}],"termid":"GO:0070428"}


id: PBO:0082998
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Cytosolic protein required for sporulation","termid":"PBO:0082998"}


id: PBO:0061283
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"nuclear pore associated protein 1 pseudogene 4","termid":"PBO:0061283"}


id: SO:0001814
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"An attribute of a coding genomic variant.","direct_ancestors":[{"relation_name":"is_a","term_name":"variant_quality","termid":"SO:0001761"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"coding_variant_quality","synonyms":[{"name":"coding variant quality","type":"exact"}],"termid":"SO:0001814"}


id: PBO:0058939
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microtubule interacting and trafficking domain containing 1","termid":"PBO:0058939"}


id: MONDO:1012163
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"bird disease","termid":"MONDO:0024905"},{"relation_name":"is_a","term_name":"micromelia, non-human animal","termid":"MONDO:1011765"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"micromelia, ducks","secondary_identifiers":["OMIA:000648-8835"],"termid":"MONDO:1012163","xrefs":{"Monarch":{"xref_id":"1012163"}}}


id: GO:0044228
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The external part of the host cell wall and/or host plasma membrane.","definition_xrefs":["GOC:rph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"host cell part","termid":"GO:0033643"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0005575"],"is_obsolete":false,"name":"host cell surface","termid":"GO:0044228"}


id: PBO:0052219
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"potassium calcium-activated channel subfamily U member 1","termid":"PBO:0052219"}


id: PBO:0081985
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger and SCAN domain containing 12","termid":"PBO:0081985"}


id: PBO:0057550
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 664a","termid":"PBO:0057550"}


id: PBO:0048763
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"GDP-mannose 4,6-dehydratase","termid":"PBO:0048763"}


id: GO:0051479
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carbohydrate biosynthetic process","termid":"GO:0016051"},{"relation_name":"is_a","term_name":"glycoside biosynthetic process","termid":"GO:0016138"},{"relation_name":"is_a","term_name":"carboxylic acid biosynthetic process","termid":"GO:0046394"},{"relation_name":"is_a","term_name":"mannosylglycerate metabolic process","termid":"GO:0051478"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005975"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0005975","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"mannosylglycerate biosynthetic process","synonyms":[{"name":"mannosylglycerate anabolism","type":"exact"},{"name":"mannosylglycerate biosynthesis","type":"exact"},{"name":"mannosylglycerate formation","type":"exact"},{"name":"mannosylglycerate synthesis","type":"exact"}],"termid":"GO:0051479"}


id: PBO:0030718
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-altered_polysaccharide_level","termid":"PBO:0030718"}


id: GO:0048354
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.","definition_xrefs":["GOC:jid","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mucilage biosynthetic process","termid":"GO:0010192"},{"relation_name":"is_a","term_name":"mucilage metabolic process involved in seed coat development","termid":"GO:0048359"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"mucilage biosynthetic process involved in seed coat development","synonyms":[{"name":"mucilage anabolism during seed coat development","type":"exact"},{"name":"mucilage biosynthetic process during seed coat development","type":"related"},{"name":"mucilage formation during seed coat development","type":"exact"},{"name":"mucilage synthesis during seed coat development","type":"exact"}],"termid":"GO:0048354"}


id: GO:0001616
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Combining with ghrelin to initiate a change in cell activity.","definition_xrefs":["GOC:mah","PMID:17983853"],"direct_ancestors":[{"relation_name":"is_a","term_name":"G protein-coupled receptor activity","termid":"GO:0004930"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0038023"}],"interesting_parent_ids":["GO:0003674","GO:0038023"],"is_obsolete":false,"name":"growth hormone secretagogue receptor activity","synonyms":[{"name":"ghrelin receptor activity","type":"exact"}],"termid":"GO:0001616"}


id: PBO:0067652
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 827, pseudogene","termid":"PBO:0067652"}


id: PBO:0065513
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"platelet activating factor receptor","termid":"PBO:0065513"}


id: MOD:01030
data:
  {"annotation_feature_type":"gene","cv_name":"PSI-MOD","definition":"modification from DeltaMass","definition_xrefs":["DeltaMass:0"],"direct_ancestors":[{"relation_name":"is_a","term_name":"DeltaMass","termid":"MOD:00947"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hydroxybenzotriazole ester","synonyms":[{"name":"HOBt","type":"exact"}],"termid":"MOD:01030"}


id: PBO:0079299
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"alpha tocopherol transfer protein","termid":"PBO:0079299"}


id: PR:P36605
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A histidinol-phosphate aminotransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02885","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"histidinol-phosphate aminotransferase (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC11B10.02c","secondary_identifiers":["UniProtKB:P36605"],"synonyms":[{"name":"Spom972h-hisC","type":"exact"},{"name":"imidazole acetol-phosphate transaminase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:P36605"}


id: PBO:0067267
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 341, pseudogene","termid":"PBO:0067267"}


id: GO:1902777
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).","definition_xrefs":["GOC:TermGenie","PMID:24463506","GO_REF:0000068","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"organic acid catabolic process","termid":"GO:0016054"},{"relation_name":"is_a","term_name":"sulfur compound catabolic process","termid":"GO:0044273"},{"relation_name":"is_a","term_name":"carbohydrate derivative catabolic process","termid":"GO:1901136"},{"relation_name":"is_a","term_name":"6-sulfoquinovose(1-) metabolic process","termid":"GO:1902776"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006790"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006790","GO:0044281","GO:0008150"],"is_obsolete":false,"name":"6-sulfoquinovose(1-) catabolic process","synonyms":[{"name":"6-sulfoquinovose(1-) breakdown","type":"exact"},{"name":"6-sulfoquinovose(1-) catabolism","type":"exact"},{"name":"6-sulfoquinovose(1-) degradation","type":"exact"}],"termid":"GO:1902777"}


id: PBO:0113154
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for their deacetylation within transcribed genes; involved in transcription coupled-nucleotide excision repair; associates with C-terminal domain (CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to cytosol in response to hypoxia","termid":"PBO:0113154"}


id: GO:1904390
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell.","definition_xrefs":["PMID:24123365","GOC:TermGenie","GO_REF:0000086"],"direct_ancestors":[{"relation_name":"is_a","term_name":"retinal bipolar neuron differentiation","termid":"GO:0060040"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"cone retinal bipolar cell differentiation","synonyms":[{"name":"cone bipolar cell differentiation","type":"exact"},{"name":"retinal cone bipolar cell differentiation","type":"exact"}],"termid":"GO:1904390"}


id: MONDO:0020566
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete Klatskin tumor (obsolete MONDO:0020566)","termid":"MONDO:0020566","xrefs":{"Monarch":{"xref_id":"0020566"}}}


id: PBO:0048229
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"G antigen 1","termid":"PBO:0048229"}


id: PBO:0113059
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Component of small ribosomal subunit (SSU) processome; interacts with the U3 snoRNA (Snr17a/b); involved in rRNA processing and maturation; required post-transcriptionally for efficient retrotransposition; absence results in decreased Ty1 Gag:GFP protein levels; originally isolated as bud-site selection mutant that displays a random budding pattern; ortholog of human NOL7","termid":"PBO:0113059"}


id: GO:0075257
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of asexual sporulation resulting in formation of a cellular spore","termid":"GO:0043945"},{"relation_name":"is_a","term_name":"regulation of teliospore formation","termid":"GO:0075256"},{"relation_name":"positively_regulates","term_name":"teliospore formation","termid":"GO:0075255"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of teliospore formation","termid":"GO:0075257"}


id: PBO:0028820
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_replication_fork_reversal","termid":"PBO:0028820"}


id: PBO:0067035
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 49, pseudogene","termid":"PBO:0067035"}


id: PBO:0048564
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"golgi associated, gamma adaptin ear containing, ARF binding protein 2","termid":"PBO:0048564"}


id: PBO:0119992
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"PTPRN2 antisense RNA 3","termid":"PBO:0119992"}


id: PBO:0061592
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"neurotrophic receptor tyrosine kinase 3","termid":"PBO:0061592"}


id: PBO:0087098
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal lysine methyltransferase; specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); nuclear SET domain containing protein; relocalizes to the cytosol in response to hypoxia","termid":"PBO:0087098"}


id: PBO:0068188
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 495","termid":"PBO:0068188"}


id: GO:0075249
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.","definition_xrefs":["GOC:pamgo_curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of asexual sporulation resulting in formation of a cellular spore","termid":"GO:0043945"},{"relation_name":"is_a","term_name":"regulation of aeciospore formation","termid":"GO:0075248"},{"relation_name":"positively_regulates","term_name":"aeciospore formation","termid":"GO:0075247"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of aeciospore formation","termid":"GO:0075249"}


id: PBO:0085615
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; relative distribution to the nucleus increases upon DNA replication stress","termid":"PBO:0085615"}


id: PBO:0002837
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RhoGEF Rgf2","termid":"PBO:0002837"}


id: GO:0160220
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (R)-lactate + ATP + D-alanine = ADP + D-alanyl-(R)-lactate + phosphate.","definition_xrefs":["RHEA:37347"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ligase activity, forming carbon-oxygen bonds","termid":"GO:0016875"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016874"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016874"],"is_obsolete":false,"name":"D-alanine-(R)-lactate ligase activity","secondary_identifiers":["KEGG_REACTION:R09588","MetaCyc:RXN-11298","EC:6.1.2.1"],"synonyms":[{"name":"D-alanyl-D-lactate ligase activity","type":"exact"}],"termid":"GO:0160220"}


id: PBO:0036071
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_histone_H3-K9_methylation_during_vegetative_growth","termid":"PBO:0036071"}


id: PBO:0027905
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_degradation_during_mitosis","termid":"PBO:0027905"}


id: GO:0016024
data:
  {"annotated_genes":["SJAG_03563","SJAG_01233","SJAG_00426","SJAG_00168"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[81855,115027,116695,121538],"is_not":false,"summary":null,"term":"GO:0016024"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.","definition_xrefs":["PMID:24533860"],"direct_ancestors":[{"relation_name":"is_a","term_name":"CDP-diacylglycerol metabolic process","termid":"GO:0046341"},{"relation_name":"is_a","term_name":"glycerophospholipid biosynthetic process","termid":"GO:0046474"}],"gene_count":4,"genes_by_uniquename":{"SJAG_00168":null,"SJAG_00426":null,"SJAG_01233":null,"SJAG_03563":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006629","GO:0008150"],"is_obsolete":false,"name":"CDP-diacylglycerol biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"PMID:25318672":null},"synonyms":[{"name":"CDP-diacylglycerol anabolism","type":"exact"},{"name":"CDP-diacylglycerol biosynthesis","type":"exact"},{"name":"CDP-diacylglycerol formation","type":"exact"},{"name":"CDP-diacylglycerol synthesis","type":"exact"}],"termid":"GO:0016024","terms_by_termid":{"GO:0016024":null}}


id: SOFP:evidenceGB
data:
  {"annotation_feature_type":"gene","cv_name":"feature_property","direct_ancestors":[{"relation_name":"is_a","term_name":"feature_property","termid":"SOFP:feature_property"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"evidenceGB","termid":"SOFP:evidenceGB"}


id: PR:O74542
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- SPCC777.03c gene.","definition_xrefs":["UniProtKB:O74542","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"uncharacterized aminotransferase C777.03c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC777.03c","synonyms":[{"name":"Spom972h-SPCC777.03c","type":"exact"}],"termid":"PR:O74542"}


id: PR:O13896
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA-directed RNA polymerase III subunit RPC10 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO00468","PANTHER:PTHR11239:SF2"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III subunit RPC10 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC22A12.05","secondary_identifiers":["UniProtKB:O13896"],"synonyms":[{"name":"DNA-directed RNA polymerases III 12.5 kDa polypeptide (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RNA polymerase III subunit C10 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RNA polymerase III subunit C11 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-POLR3K","type":"exact"}],"termid":"PR:O13896"}


id: GO:0042060
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The series of events that restore integrity to a damaged tissue, following an injury.","definition_xrefs":["PMID:15269788","GOC:bf"],"direct_ancestors":[{"relation_name":"is_a","term_name":"response to wounding","termid":"GO:0009611"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"wound healing","secondary_identifiers":["Wikipedia:Wound_healing"],"termid":"GO:0042060"}


id: PBO:0069337
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, U6 small nuclear 597, pseudogene","termid":"PBO:0069337"}


id: FYPO:0001580
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing leucine as the nitrogen source.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0000003"}],"interesting_parent_ids":["FYPO:0000139","FYPO:0000003","FYPO:0002058","FYPO:0000257","FYPO:0002060","FYPO:0002057"],"is_obsolete":false,"name":"normal growth on leucine nitrogen source","synonyms":[{"name":"normal cell population growth on leucine nitrogen source","type":"exact"},{"name":"normal cell population growth on monomeric leucine nitrogen source","type":"exact"},{"name":"normal leucine utilization","type":"related"},{"name":"normal monomeric leucine utilization","type":"related"},{"name":"normal vegetative cell population growth on leucine nitrogen source","type":"exact"}],"termid":"FYPO:0001580"}


id: MONDO:0005209
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","gene_count":0,"genotype_count":0,"name":"obsolete cutaneous T-cell lymphoma (obsolete MONDO:0005209)","termid":"MONDO:0005209","xrefs":{"Monarch":{"xref_id":"0005209"}}}


id: PBO:0067562
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 715, pseudogene","termid":"PBO:0067562"}


id: GO:0047622
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.","definition_xrefs":["MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN","EC:3.2.2.7"],"direct_ancestors":[{"relation_name":"is_a","term_name":"purine nucleosidase activity","termid":"GO:0008477"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016798"},{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016787"}],"interesting_parent_ids":["GO:0003824","GO:0003674","GO:0016787","GO:0016798"],"is_obsolete":false,"name":"adenosine nucleosidase activity","secondary_identifiers":["RHEA:18669"],"synonyms":[{"name":"ANase activity","type":"related"},{"name":"N-ribosyladenine ribohydrolase activity","type":"related"},{"name":"adenosinase activity","type":"related"},{"name":"adenosine hydrolase activity","type":"related"},{"name":"adenosine ribohydrolase activity","type":"related"}],"termid":"GO:0047622"}


id: MONDO:0000756
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"An embryonal rhabdomyosarcoma located in the parameningeal region.","definition_xrefs":["PMID:10717216","DOID:0060338","PMID:23021437"],"direct_ancestors":[{"relation_name":"is_a","term_name":"embryonal rhabdomyosarcoma","termid":"MONDO:0009993"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0004992"],"is_obsolete":false,"name":"parameningeal embryonal rhabdomyosarcoma","termid":"MONDO:0000756","xrefs":{"Monarch":{"xref_id":"0000756"}}}


id: FYPO:0004681
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature polyadenylated 5.8S rRNA measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased mature 5.8S rRNA level","termid":"FYPO:0001138"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"output_of","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"output_of","termid":"FYPO:0006551"},{"rel_name":"output_of","termid":"FYPO:0005447"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0001985","FYPO:0000002","FYPO:0006551","FYPO:0005447"],"is_obsolete":false,"name":"decreased polyadenylated 5.8S rRNA level","synonyms":[{"name":"decreased 5.8S rRNA level during mitotic cell cycle","type":"related"},{"name":"decreased mature polyadenylated 5.8S rRNA transcript level","type":"exact"},{"name":"decreased polyadenylated 5.8S rRNA accumulation","type":"related"},{"name":"decreased polyadenylated 5.8S rRNA level during vegetative growth","type":"exact"},{"name":"decreased polyadenylated 5.8S rRNA transcript level","type":"exact"},{"name":"reduced polyadenylated 5.8S rRNA level","type":"exact"}],"termid":"FYPO:0004681"}


id: GO:0035768
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).","definition_xrefs":["GOC:BHF","CL:0000115"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell chemotaxis to fibroblast growth factor","termid":"GO:0035766"},{"relation_name":"is_a","term_name":"endothelial cell chemotaxis","termid":"GO:0035767"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endothelial cell chemotaxis to fibroblast growth factor","termid":"GO:0035768"}


id: GO:0042795
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.","definition_xrefs":["GOC:jl","ISBN:0321000382"],"direct_ancestors":[{"relation_name":"is_a","term_name":"transcription by RNA polymerase II","termid":"GO:0006366"},{"relation_name":"is_a","term_name":"snRNA transcription","termid":"GO:0009301"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016073"},{"rel_name":"is_a","termid":"GO:0006351"},{"rel_name":"part_of","termid":"GO:0010467"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0006351","GO:0016073","GO:0008150","GO:0010467"],"is_obsolete":false,"name":"snRNA transcription by RNA polymerase II","secondary_identifiers":["Reactome:R-HSA-6807505"],"synonyms":[{"name":"snRNA transcription from Pol II promoter","type":"exact"},{"name":"snRNA transcription from RNA polymerase II promoter","type":"exact"}],"termid":"GO:0042795"}


id: PBO:0045144
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"dynein axonemal heavy chain 1","termid":"PBO:0045144"}


id: PBO:0043959
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crystallin gamma D","termid":"PBO:0043959"}


id: GO:0006506
data:
  {"annotated_genes":["SJAG_01416","SJAG_03801","SJAG_03506","SJAG_00295","SJAG_04975","SJAG_04881","SJAG_02913","SJAG_03672","SJAG_02523","SJAG_01860","SJAG_01227","SJAG_03292","SJAG_02488","SJAG_03066","SJAG_03878","SJAG_05327","SJAG_02804","SJAG_04119","SJAG_04165","SJAG_01570","SJAG_00068","SJAG_04924","SJAG_06383","SJAG_04337","SJAG_05278","SJAG_02776","SJAG_03115","SJAG_00831","SJAG_06425","SJAG_00846"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[58089,58341,58502,58516,61205,63366,64287,64497,71574,73651,74628,74905,75222,76735,77261,77277,78152,78200,78937,79250,79261,79423,79453,79680,80063,89296,91433,94889,105658,105720],"is_not":false,"summary":null,"term":"GO:0006506"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.","definition_xrefs":["GOC:go_curators","ISBN:0198547684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"GPI anchor metabolic process","termid":"GO:0006505"},{"relation_name":"is_a","term_name":"phosphatidylinositol biosynthetic process","termid":"GO:0006661"},{"relation_name":"is_a","term_name":"glycolipid biosynthetic process","termid":"GO:0009247"},{"relation_name":"part_of","term_name":"GPI anchored protein biosynthesis","termid":"GO:0180046"}],"gene_count":30,"genes_by_uniquename":{"SJAG_00068":null,"SJAG_00295":null,"SJAG_00831":null,"SJAG_00846":null,"SJAG_01227":null,"SJAG_01416":null,"SJAG_01570":null,"SJAG_01860":null,"SJAG_02488":null,"SJAG_02523":null,"SJAG_02776":null,"SJAG_02804":null,"SJAG_02913":null,"SJAG_03066":null,"SJAG_03115":null,"SJAG_03292":null,"SJAG_03506":null,"SJAG_03672":null,"SJAG_03801":null,"SJAG_03878":null,"SJAG_04119":null,"SJAG_04165":null,"SJAG_04337":null,"SJAG_04881":null,"SJAG_04924":null,"SJAG_04975":null,"SJAG_05278":null,"SJAG_05327":null,"SJAG_06383":null,"SJAG_06425":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"part_of","termid":"GO:0051604"},{"rel_name":"is_a","termid":"GO:0006629"},{"rel_name":"part_of","termid":"GO:0010467"}],"interesting_parent_ids":["GO:0051604","GO:0010467","GO:0006629","GO:0008150"],"is_obsolete":false,"name":"GPI anchor biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000041":null,"GO_REF:0000107":null},"secondary_identifiers":["Reactome:R-HSA-162710","GO:0015998"],"synonyms":[{"name":"GPI anchor anabolism","type":"exact"},{"name":"GPI anchor biosynthesis","type":"exact"},{"name":"GPI anchor formation","type":"exact"},{"name":"GPI anchor synthesis","type":"exact"},{"name":"GPI/GSI anchor biosynthesis","type":"broad"},{"name":"GPI/GSI anchor biosynthetic process","type":"broad"},{"name":"glycosylphosphatidylinositol biosynthesis","type":"exact"},{"name":"glycosylphosphatidylinositol biosynthetic process","type":"exact"}],"termid":"GO:0006506","terms_by_termid":{"GO:0006506":null}}


id: MONDO:0016599
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"OBSOLETE. Autosomal dominant form of secondary polycythemia.","definition_xrefs":["MONDO:patterns/autosomal_dominant"],"gene_count":0,"genotype_count":0,"name":"obsolete autosomal dominant secondary polycythemia (obsolete MONDO:0016599)","secondary_identifiers":["Orphanet:247511"],"synonyms":[{"name":"autosomal dominant secondary erythrocytosis","type":"exact"},{"name":"secondary polycythemia, autosomal dominant","type":"exact"}],"termid":"MONDO:0016599","xrefs":{"Monarch":{"xref_id":"0016599"}}}


id: GO:0008651
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:ai"],"gene_count":0,"genotype_count":0,"name":"obsolete actin polymerizing activity (obsolete GO:0008651)","synonyms":[{"name":"actin polymerizing activity","type":"exact"}],"termid":"GO:0008651"}


id: GO:1990653
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The chemical reactions and pathways resulting in the formation of a monounsaturated fatty acid. A monounsaturated fatty acid has one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded, as opposed to polyunsaturated fatty acids.","definition_xrefs":["PMID:16443825","GOC:hjd"],"gene_count":0,"genotype_count":0,"name":"obsolete monounsaturated fatty acid biosynthetic process (obsolete GO:1990653)","termid":"GO:1990653"}


id: GO:0050040
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (S)-lactate + O2 = acetate + CO2 + H2O.","definition_xrefs":["EC:1.13.12.4","RHEA:16513"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)","termid":"GO:0016703"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003824"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"}],"interesting_parent_ids":["GO:0016491","GO:0003674","GO:0003824"],"is_obsolete":false,"name":"lactate 2-monooxygenase activity","secondary_identifiers":["KEGG_REACTION:R00319","MetaCyc:RXN-19631"],"synonyms":[{"name":"(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)","type":"related"},{"name":"L-lactate monooxygenase activity","type":"related"},{"name":"L-lactate-2-monooxygenase activity","type":"related"},{"name":"lactate monooxygenase activity","type":"related"},{"name":"lactate oxidase activity","type":"related"},{"name":"lactate oxidative decarboxylase activity","type":"related"},{"name":"lactate oxygenase activity","type":"related"},{"name":"lactic oxidase activity","type":"related"},{"name":"lactic oxygenase activity","type":"related"}],"termid":"GO:0050040"}


id: MONDO:0020368
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Axenfeld's anomaly is a rare congenital ocular defect caused by anterior segment dysgenesis and is characterized by anteriorly displaced Schwalbe's line and iris bands extending into the cornea. In contrast, Rieger's anomaly includes characteristic iris and pupil anomalies.","definition_xrefs":["Orphanet:98978"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"obsolete goniodysgenesis (obsolete MONDO:0020218)","termid":"MONDO:0020218"},{"relation_name":"is_a","term_name":"eye disorder","termid":"MONDO:0005328"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005328"}],"interesting_parent_ids":["MONDO:0005328"],"is_obsolete":false,"name":"Axenfeld anomaly","secondary_identifiers":["UMLS:C0266548","icd11.foundation:1703498511","SCTID:204152008","GARD:16485","MEDGEN:78611","MedDRA:10058653","ICD9:743.44"],"termid":"MONDO:0020368","xrefs":{"Monarch":{"xref_id":"0020368"}}}


id: MONDO:0007742
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"hereditary disease","termid":"MONDO:0003847"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5-hydroxytryptamine oxygenase regulator","secondary_identifiers":["OMIM:143460","UMLS:C3887951","MEDGEN:854659"],"synonyms":[{"name":"5-HYDROXYTRYPTAMINE oxygenase regulator","type":"related"},{"name":"5-hydroxytryptamine oxygenase regulator","type":"exact"},{"name":"HTOR","type":"related"}],"termid":"MONDO:0007742","xrefs":{"Monarch":{"xref_id":"0007742"}}}


id: PBO:0057416
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 548q","termid":"PBO:0057416"}


id: FYPO:0003848
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrazinocurcumin. Cells stop growing (and may die) at a concentration of hydrazinocurcumin that allows wild type cells to grow.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"increased sensitivity to chemical during vegetative growth","termid":"FYPO:0000127"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002683"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0000139","FYPO:0000003","FYPO:0002683","FYPO:0005447"],"is_obsolete":false,"name":"sensitive to hydrazinocurcumin","synonyms":[{"name":"hypersensitive to hydrazinocurcumin","type":"exact"},{"name":"sensitive to hydrazinocurcumin during mitotic cell cycle","type":"related"},{"name":"sensitive to hydrazinocurcumin during vegetative growth","type":"exact"}],"termid":"FYPO:0003848"}


id: GO:0052127
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. The directed movement of an organism or motile cell on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:mtg_pamgo_17jul06"],"gene_count":0,"genotype_count":0,"name":"obsolete movement on or near host (obsolete GO:0052127)","termid":"GO:0052127"}


id: PBO:0090536
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane ammonium transmembrane transporter Amt1","termid":"PBO:0090536"}


id: MONDO:0800437
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare condition characterized by the association of hypotonia, Moebius sequence (bilateral congenital facial palsy with impairment of ocular abduction), Pierre-Robin sequence (micrognathia, glossoptosis, and high-arched or cleft palate), unusual face, and growth delay.","definition_xrefs":["Orphanet:1358"],"direct_ancestors":[{"relation_name":"excluded_subClassOf","term_name":"multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome","termid":"MONDO:0015160"},{"relation_name":"excluded_subClassOf","term_name":"obsolete Mendelian syndromes with cleft lip/palate (obsolete MONDO:0015335)","termid":"MONDO:0015335"},{"relation_name":"is_a","term_name":"Carey-Fineman-Ziter syndrome","termid":"MONDO:0031415"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Carey-Fineman-Ziter syndrome 1","secondary_identifiers":["MEDGEN:1804638","UMLS:C5676876","ICD9:359.89","SCTID:429753001","DOID:0080194","MESH:C536102","OMIM:254940"],"synonyms":[{"name":"CFZS","type":"related"},{"name":"CFZS1","type":"exact"},{"name":"Carey Fineman Ziter syndrome","type":"related"},{"name":"Carey-Fineman-Ziter syndrome 1","type":"exact"},{"name":"Moebius sequence, Robin complex, and hypotonia","type":"related"},{"name":"congenital nonprogressive myopathy with Moebius and Robin sequences","type":"related"},{"name":"myopathy, congenital nonprogressive with Moebius and Robin sequences","type":"related"},{"name":"myopathy, congenital nonprogressive, with Moebius sequence and Robin sequence","type":"exact"},{"name":"myopathy-Moebius-Robin syndrome","type":"exact"}],"termid":"MONDO:0800437","xrefs":{"Monarch":{"xref_id":"0800437"}}}


id: FYPO:0005931
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at the silent mating-type cassettes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes.","definition_xrefs":["PMID:24662054","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased nucleosome occupancy","termid":"FYPO:0004491"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000641"},{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001320","FYPO:0000002","FYPO:0000641","FYPO:0005447","FYPO:0001985"],"is_obsolete":false,"name":"decreased nucleosome occupancy at silent mating-type cassette","synonyms":[{"name":"decreased nucleosome occupancy at mating-type region heterochromatin","type":"exact"},{"name":"decreased nucleosome occupancy at silent mating-type cassette during mitotic cell cycle","type":"related"},{"name":"decreased nucleosome occupancy at silent mating-type cassette during vegetative growth","type":"exact"},{"name":"decreased nucleosome occupancy in silent mating-type cassette","type":"exact"},{"name":"reduced nucleosome occupancy at silent mating-type cassette","type":"exact"}],"termid":"FYPO:0005931"}


id: PBO:0090106
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"squalene cyclase-like protein","termid":"PBO:0090106"}


id: PBO:0052342
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"kinesin family member 1C","termid":"PBO:0052342"}


id: GO:0001630
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. (Was not defined before being made obsolete).","definition_xrefs":["GOC:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete GP40-like receptor activity (obsolete GO:0001630)","synonyms":[{"name":"GP40-like receptor activity","type":"exact"}],"termid":"GO:0001630"}


id: GO:1903657
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis.","definition_xrefs":["PMID:25049409","GO_REF:0000058","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of cell projection organization","termid":"GO:0031345"},{"relation_name":"is_a","term_name":"regulation of type IV pilus biogenesis","termid":"GO:1903656"},{"relation_name":"negatively_regulates","term_name":"type IV pilus assembly","termid":"GO:0043683"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0044085"}],"interesting_parent_ids":["GO:0008150","GO:0044085"],"is_obsolete":false,"name":"negative regulation of type IV pilus biogenesis","synonyms":[{"name":"down regulation of TFP biogenesis","type":"exact"},{"name":"down regulation of type 4 pilus biogenesis","type":"exact"},{"name":"down regulation of type IV fimbria assembly","type":"exact"},{"name":"down regulation of type IV fimbria biogenesis","type":"exact"},{"name":"down regulation of type IV fimbriae assembly","type":"exact"},{"name":"down regulation of type IV fimbriae biogenesis","type":"exact"},{"name":"down regulation of type IV fimbrial assembly","type":"exact"},{"name":"down regulation of type IV fimbrial biogenesis","type":"exact"},{"name":"down regulation of type IV fimbrium assembly","type":"exact"},{"name":"down regulation of type IV fimbrium biogenesis","type":"exact"},{"name":"down regulation of type IV pilus biogenesis","type":"exact"},{"name":"down regulation of type IV pilus biosynthesis","type":"exact"},{"name":"down-regulation of TFP biogenesis","type":"exact"},{"name":"down-regulation of type 4 pilus biogenesis","type":"exact"},{"name":"down-regulation of type IV fimbria assembly","type":"exact"},{"name":"down-regulation of type IV fimbria biogenesis","type":"exact"},{"name":"down-regulation of type IV fimbriae assembly","type":"exact"},{"name":"down-regulation of type IV fimbriae biogenesis","type":"exact"},{"name":"down-regulation of type IV fimbrial assembly","type":"exact"},{"name":"down-regulation of type IV fimbrial biogenesis","type":"exact"},{"name":"down-regulation of type IV fimbrium assembly","type":"exact"},{"name":"down-regulation of type IV fimbrium biogenesis","type":"exact"},{"name":"down-regulation of type IV pilus biogenesis","type":"exact"},{"name":"down-regulation of type IV pilus biosynthesis","type":"exact"},{"name":"downregulation of TFP biogenesis","type":"exact"},{"name":"downregulation of type 4 pilus biogenesis","type":"exact"},{"name":"downregulation of type IV fimbria assembly","type":"exact"},{"name":"downregulation of type IV fimbria biogenesis","type":"exact"},{"name":"downregulation of type IV fimbriae assembly","type":"exact"},{"name":"downregulation of type IV fimbriae biogenesis","type":"exact"},{"name":"downregulation of type IV fimbrial assembly","type":"exact"},{"name":"downregulation of type IV fimbrial biogenesis","type":"exact"},{"name":"downregulation of type IV fimbrium assembly","type":"exact"},{"name":"downregulation of type IV fimbrium biogenesis","type":"exact"},{"name":"downregulation of type IV pilus biogenesis","type":"exact"},{"name":"downregulation of type IV pilus biosynthesis","type":"exact"},{"name":"inhibition of TFP biogenesis","type":"narrow"},{"name":"inhibition of type 4 pilus biogenesis","type":"narrow"},{"name":"inhibition of type IV fimbria assembly","type":"narrow"},{"name":"inhibition of type IV fimbria biogenesis","type":"narrow"},{"name":"inhibition of type IV fimbriae assembly","type":"narrow"},{"name":"inhibition of type IV fimbriae biogenesis","type":"narrow"},{"name":"inhibition of type IV fimbrial assembly","type":"narrow"},{"name":"inhibition of type IV fimbrial biogenesis","type":"narrow"},{"name":"inhibition 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id: GO:0080160
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id: PBO:0044734
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id: GO:1905150
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id: PBO:0017967
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id: GO:0035336
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id: PBO:0085466
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id: PBO:0075920
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id: GO:0008652
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id: GO:0016787
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id: GO:1903688
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that activates or increases the frequency, rate or extent of border follicle cell migration.","definition_xrefs":["GOC:TermGenie","PMID:18394891","GO_REF:0000058","GOC:als"],"direct_ancestors":[{"relation_name":"is_a","term_name":"positive regulation of epithelial cell migration","termid":"GO:0010634"},{"relation_name":"is_a","term_name":"regulation of border follicle cell migration","termid":"GO:1903684"},{"relation_name":"positively_regulates","term_name":"border follicle cell migration","termid":"GO:0007298"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"positive regulation of border follicle cell migration","synonyms":[{"name":"activation of border follicle cell migration","type":"narrow"}],"termid":"GO:1903688"}


id: PBO:0113000
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Alpha-factor mating pheromone made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor; binds copper(II) ions","termid":"PBO:0113000"}


id: GO:0042539
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"hypotonic response","termid":"GO:0006971"},{"relation_name":"is_a","term_name":"response to salt stress","termid":"GO:0009651"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"hypotonic salinity response","synonyms":[{"name":"response to hypotonic salt stress","type":"exact"}],"termid":"GO:0042539"}


id: GO:2000112
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process.","definition_xrefs":["GOC:obol"],"gene_count":0,"genotype_count":0,"name":"obsolete regulation of cellular macromolecule biosynthetic process (obsolete GO:2000112)","synonyms":[{"name":"regulation of cellular biopolymer biosynthetic process","type":"exact"},{"name":"regulation of cellular macromolecule anabolism","type":"exact"},{"name":"regulation of cellular macromolecule biosynthesis","type":"exact"},{"name":"regulation of cellular macromolecule formation","type":"exact"},{"name":"regulation of cellular macromolecule synthesis","type":"exact"}],"termid":"GO:2000112"}


id: PBO:0117016
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"KIRREL3 antisense RNA 4","termid":"PBO:0117016"}


id: PBO:0051924
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"integrin subunit beta 6","termid":"PBO:0051924"}


id: GO:0047037
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: (7S)-salutaridinol + NADP+ = H+ + NADPH + salutaridine.","definition_xrefs":["EC:1.1.1.248","RHEA:10108"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","termid":"GO:0016616"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0016491","GO:0003824"],"is_obsolete":false,"name":"salutaridine reductase (NADPH) activity","secondary_identifiers":["MetaCyc:1.1.1.248-RXN","KEGG_REACTION:R04697"],"synonyms":[{"name":"salutaridinol:NADP+ 7-oxidoreductase activity","type":"related"}],"termid":"GO:0047037"}


id: MONDO:0013844
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"stutter disorder","termid":"MONDO:0000723"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"stuttering, familial persistent, 4","secondary_identifiers":["OMIM:614668","UMLS:C3553403","MEDGEN:766317"],"synonyms":[{"name":"STUT4","type":"exact"},{"name":"stuttering, familial persistent, 4","type":"exact"}],"termid":"MONDO:0013844","xrefs":{"Monarch":{"xref_id":"0013844"}}}


id: CHEBI:16414
data:
  {"annotation_feature_type":"gene","cv_name":"chebi_ontology","direct_ancestors":[{"relation_name":"is_a","term_name":"chemical entity","termid":"CHEBI:24431"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"L-valine","termid":"CHEBI:16414"}


id: PBO:0068190
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 5S ribosomal pseudogene 497","termid":"PBO:0068190"}


id: GO:0004466
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"Catalysis of the reaction: a long-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.","definition_xrefs":["RHEA:17721"],"direct_ancestors":[{"relation_name":"is_a","term_name":"acyl-CoA dehydrogenase activity","termid":"GO:0003995"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0016491"},{"rel_name":"is_a","termid":"GO:0003674"},{"rel_name":"is_a","termid":"GO:0003824"}],"interesting_parent_ids":["GO:0003674","GO:0003824","GO:0016491"],"is_obsolete":false,"name":"long-chain fatty acyl-CoA dehydrogenase activity","secondary_identifiers":["MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN","EC:1.3.8.8"],"synonyms":[{"name":"long-chain acyl-coenzyme A dehydrogenase activity","type":"related"},{"name":"long-chain-acyl-CoA dehydrogenase activity","type":"exact"},{"name":"palmitoyl-CoA dehydrogenase activity","type":"narrow"},{"name":"palmitoyl-coenzyme A dehydrogenase activity","type":"narrow"}],"termid":"GO:0004466"}


id: PBO:0061550
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"5'-nucleotidase, cytosolic IIIA","termid":"PBO:0061550"}


id: PBO:0039587
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"anoctamin 5","termid":"PBO:0039587"}


id: FYPO:0005006
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype in which the phosphorylation of serine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type).","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete normal protein serine phosphorylation (obsolete FYPO:0005006)","synonyms":[{"name":"normal peptidyl-serine phosphorylation","type":"exact"}],"termid":"FYPO:0005006"}


id: MONDO:0025100
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Inflammation of the udder in cows.","definition_xrefs":["MESH:D008414"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cattle disease","termid":"MONDO:0024913"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mastitis, bovine","synonyms":[{"name":"Mastitides, bovine","type":"related"},{"name":"bovine Mastitides","type":"related"},{"name":"bovine mastitis","type":"related"}],"termid":"MONDO:0025100","xrefs":{"Monarch":{"xref_id":"0025100"}}}


id: PR:Q9UTA1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- loz1 gene.","definition_xrefs":["PRO:DNx","UniProtKB:Q9UTA1"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"zinc finger protein C25B8.19c (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC25B8.19c","synonyms":[{"name":"Spom972h-loz1","type":"exact"}],"termid":"PR:Q9UTA1"}


id: PBO:0054229
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1611","termid":"PBO:0054229"}


id: PR:O74883
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A DNA-directed RNA polymerase III subunit RPC5 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR12069:SF0","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DNA-directed RNA polymerase III subunit rpc5 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC330.13","secondary_identifiers":["UniProtKB:O74883"],"synonyms":[{"name":"RNA polymerase III subunit C37 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"RNA polymerase III subunit C5 (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"SPCC330.13","type":"related"},{"name":"Spom972h-POLR3E","type":"exact"}],"termid":"PR:O74883"}


id: PBO:0062249
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"olfactory receptor family 5 subfamily BP member 1 pseudogene","termid":"PBO:0062249"}


id: PBO:0017897
data:
  {"annotation_feature_type":"gene","cv_name":"complementation","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"functionally complemented by human EIF3E","termid":"PBO:0017897"}


id: FYPO:0001149
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methylamine.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal vegetative cell population growth","termid":"FYPO:0001357"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0002058"},{"rel_name":"is_a","termid":"FYPO:0000003"},{"rel_name":"is_a","termid":"FYPO:0002060"},{"rel_name":"is_a","termid":"FYPO:0002057"},{"rel_name":"is_a","termid":"FYPO:0000139"},{"rel_name":"is_a","termid":"FYPO:0000257"}],"interesting_parent_ids":["FYPO:0000003","FYPO:0002057","FYPO:0000139","FYPO:0002058","FYPO:0002060","FYPO:0000257"],"is_obsolete":false,"name":"normal growth on methylamine","synonyms":[{"name":"normal cell population growth in presence of methylamine","type":"exact"},{"name":"normal cell population growth on methylamine","type":"exact"},{"name":"normal cellular response to methylamine","type":"related"},{"name":"normal vegetative cell population growth on methylamine","type":"exact"}],"termid":"FYPO:0001149"}


id: GO:1990215
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a symbiont alters or subverts vesicle-mediated transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["PMID:30893609","PMID:24248335","PMID:31492901","PMID:22319451"],"direct_ancestors":[{"relation_name":"is_a","term_name":"symbiont-mediated perturbation of host cellular process","termid":"GO:0044068"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"symbiont-mediated perturbation of host vesicle-mediated transport","synonyms":[{"name":"negative regulation by symbiont of host intracellular transport","type":"broad"},{"name":"symbiont-mediated perturbation of host endosomal trafficking","type":"related"}],"termid":"GO:1990215"}


id: PBO:0090921
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"plasma membrane mannan endo-1,6-alpha-mannosidase Dfg501","termid":"PBO:0090921"}


id: FYECO:0000052
data:
  {"annotation_feature_type":"gene","cv_name":"fission_yeast_phenotype_condition","definition":"An experimental condition in which arachidic acid was added to the medium or assay buffer in excess compared to standard medium or assay buffers.","definition_xrefs":["PomBase:al"],"direct_ancestors":[{"relation_name":"is_a","term_name":"+ fatty acid","termid":"FYECO:0000042"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"+ arachidic acid","termid":"FYECO:0000052"}


id: GO:0004442
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the reaction: D-myo-inositol 1,3-bisphosphate + H2O = D-myo-inositol 1-monophosphate + phosphate.","definition_xrefs":["EC:3.1.3.65","GOC:go_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete inositol-1,4,-bisphosphate 3-phosphatase (obsolete GO:0004442)","synonyms":[{"name":"inositol-1,4,-bisphosphate 3-phosphatase","type":"exact"}],"termid":"GO:0004442"}


id: PBO:0078482
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"tRNA-Ile (anticodon AAT) 5-2","termid":"PBO:0078482"}


id: GO:0051872
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"sphingosine metabolic process","termid":"GO:0006670"},{"relation_name":"is_a","term_name":"diol catabolic process","termid":"GO:0034313"},{"relation_name":"is_a","term_name":"sphingoid catabolic process","termid":"GO:0046521"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006629"}],"interesting_parent_ids":["GO:0006629","GO:0008150","GO:0044281"],"is_obsolete":false,"name":"sphingosine catabolic process","synonyms":[{"name":"(4E)-sphing-4-enine catabolic process","type":"exact"},{"name":"(4E)-sphing-4-enine catabolism","type":"exact"},{"name":"sphing-4-enine catabolic process","type":"exact"},{"name":"sphing-4-enine catabolism","type":"exact"}],"termid":"GO:0051872"}


id: PBO:0053072
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"lipopolysaccharide binding protein","termid":"PBO:0053072"}


id: PBO:0056846
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"O-6-methylguanine-DNA methyltransferase","termid":"PBO:0056846"}


id: GO:0046225
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.","definition_xrefs":["GOC:ai"],"direct_ancestors":[{"relation_name":"is_a","term_name":"toxin catabolic process","termid":"GO:0009407"},{"relation_name":"is_a","term_name":"peptide antibiotic catabolic process","termid":"GO:0030652"},{"relation_name":"is_a","term_name":"bacteriocin metabolic process","termid":"GO:0046224"},{"relation_name":"is_a","term_name":"detoxification of nitrogen compound","termid":"GO:0051410"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0019748"},{"rel_name":"is_a","termid":"GO:0098754"}],"interesting_parent_ids":["GO:0098754","GO:0008150","GO:0019748"],"is_obsolete":false,"name":"bacteriocin catabolic process","synonyms":[{"name":"bacteriocin breakdown","type":"exact"},{"name":"bacteriocin catabolism","type":"exact"},{"name":"bacteriocin degradation","type":"exact"}],"termid":"GO:0046225"}


id: PBO:0089332
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"HSP chaperone complex subunit Cns1","termid":"PBO:0089332"}


id: MONDO:0002478
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A biphasic neoplasm that arises from the ovary or the testis. It is characterized by the presence of neoplastic germ cells and neoplastic sex cord-stromal cells. It includes the gonadoblastoma and mixed germ cell-sex cord stromal tumor, unclassifiable.","definition_xrefs":["NCIT:C5241"],"direct_ancestors":[{"relation_name":"is_a","term_name":"mixed neoplasm","termid":"MONDO:0021043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"mixed germ cell-sex cord-stromal tumor","secondary_identifiers":["MEDGEN:232941","DOID:2996","UMLS:C1321220"],"synonyms":[{"name":"mixed germ cell-Sex cord neoplasm","type":"exact"},{"name":"mixed germ cell-Sex cord tumor","type":"exact"},{"name":"mixed germ cell-Sex cord tumour","type":"exact"},{"name":"mixed germ cell-Sex cord-stromal neoplasm","type":"exact"},{"name":"mixed germ cell-Sex cord-stromal tumor","type":"exact"},{"name":"mixed germ cell-Sex cord-stromal tumour","type":"exact"},{"name":"mixed germ cell-sex cord-stromal tumor (morphologic abnormality)","type":"exact"},{"name":"mixed germ cell-sex cord-stromal tumour (morphologic abnormality)","type":"exact"}],"termid":"MONDO:0002478","xrefs":{"Monarch":{"xref_id":"0002478"}}}


id: PR:O94415
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR11815:SF0","PRO:DNx","OMA:SCHPO04968"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPCC1620.08","secondary_identifiers":["UniProtKB:O94415"],"synonyms":[{"name":"SCS-beta (Schizosaccharomyces pombe 972h-)","type":"exact"},{"name":"Spom972h-SUCLA2","type":"exact"},{"name":"succinyl-CoA synthetase beta chain (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:O94415"}


id: PBO:0059884
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"MT-ND1 pseudogene 7","termid":"PBO:0059884"}


id: PR:Q10342
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein SDA1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR12730:SF0","PRO:DNx","OMA:SCHPO02440"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"protein sda1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC106.14c","secondary_identifiers":["UniProtKB:Q10342"],"synonyms":[{"name":"Spom972h-SDAD1","type":"exact"}],"termid":"PR:Q10342"}


id: GO:0034036
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.","definition_xrefs":["GOC:pde","GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ribonucleoside bisphosphate biosynthetic process","termid":"GO:0034030"},{"relation_name":"is_a","term_name":"purine nucleoside bisphosphate biosynthetic process","termid":"GO:0034033"},{"relation_name":"is_a","term_name":"purine ribonucleoside bisphosphate metabolic process","termid":"GO:0034035"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0044281"},{"rel_name":"is_a","termid":"GO:0055086"}],"interesting_parent_ids":["GO:0008150","GO:0044281","GO:0055086"],"is_obsolete":false,"name":"purine ribonucleoside bisphosphate biosynthetic process","synonyms":[{"name":"purine ribonucleoside bisphosphate anabolism","type":"exact"},{"name":"purine ribonucleoside bisphosphate biosynthesis","type":"exact"},{"name":"purine ribonucleoside bisphosphate formation","type":"exact"},{"name":"purine ribonucleoside bisphosphate synthesis","type":"exact"}],"termid":"GO:0034036"}


id: PBO:0004210
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DASH complex subunit Duo1","termid":"PBO:0004210"}


id: PBO:0054545
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1945","termid":"PBO:0054545"}


id: GO:0071896
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process in which a protein is transported to, and/or maintained at the adherens junction.","definition_xrefs":["PMID:26412237","GOC:mah","GOC:aruk","GOC:bc","GOC:BHF"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to cell-cell junction","termid":"GO:0150105"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to adherens junction","secondary_identifiers":["GO:1904696"],"synonyms":[{"name":"protein localisation in adherens junction","type":"exact"},{"name":"protein localisation in cell-cell adherens junction","type":"exact"},{"name":"protein localisation to adherens junction","type":"exact"},{"name":"protein localisation to cell-cell adherens junction","type":"exact"},{"name":"protein localization in adherens junction","type":"exact"},{"name":"protein localization in cell-cell adherens junction","type":"exact"},{"name":"protein localization to cell-cell adherens junction","type":"exact"}],"termid":"GO:0071896"}


id: PBO:0110167
data:
  {"annotation_feature_type":"gene","cv_name":"pubprop_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"canto_approver_orcid","termid":"PBO:0110167"}


id: MONDO:0020644
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A rare non-Hodgkin lymphoma that arises in and is confined to the lung at the time of diagnosis. Representative examples include bronchial mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma.","definition_xrefs":["NCIT:C5684"],"direct_ancestors":[{"relation_name":"is_a","term_name":"lung lymphoma","termid":"MONDO:0003987"},{"relation_name":"is_a","term_name":"non-Hodgkin lymphoma","termid":"MONDO:0018908"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005570"},{"rel_name":"is_a","termid":"MONDO:0004992"}],"interesting_parent_ids":["MONDO:0005570","MONDO:0004992"],"is_obsolete":false,"name":"lung non-Hodgkin lymphoma","secondary_identifiers":["UMLS:C1334453","MEDGEN:235267"],"synonyms":[{"name":"lung non-Hodgkin lymphoma","type":"exact"},{"name":"lung non-Hodgkin's lymphoma","type":"exact"},{"name":"non-Hodgkin lymphoma of lung","type":"exact"},{"name":"primary lung non-Hodgkin's lymphoma","type":"exact"}],"termid":"MONDO:0020644","xrefs":{"Monarch":{"xref_id":"0020644"}}}


id: FYPO:0002996
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A regulation phenotype in which regulation of DNA replication during the mitotic cell cycle is normal (i.e. indistinguishable from wild type) during a cellular response to hydrogen peroxide.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"normal regulation of mitotic cell cycle","termid":"FYPO:0001928"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0000257"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001312"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001320","FYPO:0000257","FYPO:0001312"],"is_obsolete":false,"name":"normal negative regulation of DNA replication during cellular response to hydrogen peroxide","synonyms":[{"name":"normal negative regulation of DNA replication during cellular response to H2O2","type":"exact"},{"name":"normal negative regulation of nuclear cell cycle DNA replication during cellular response to hydrogen peroxide","type":"exact"}],"termid":"FYPO:0002996"}


id: PR:Q9P3W1
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A general transcription factor IIE subunit 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PANTHER:PTHR13097:SF3","PRO:DNx"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transcription initiation factor IIE subunit alpha (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPAC458.07","secondary_identifiers":["UniProtKB:Q9P3W1"],"synonyms":[{"name":"SPAC458.07","type":"related"},{"name":"Spom972h-GTF2E1","type":"exact"},{"name":"TFIIE-alpha (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P3W1"}


id: GO:0052837
data:
  {"annotated_genes":["SJAG_00827"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[75444],"is_not":false,"summary":null,"term":"GO:0052837"}]},"cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.","definition_xrefs":["GOC:curators"],"direct_ancestors":[{"relation_name":"is_a","term_name":"oxazole or thiazole biosynthetic process","termid":"GO:0018131"},{"relation_name":"is_a","term_name":"sulfur compound biosynthetic process","termid":"GO:0044272"},{"relation_name":"is_a","term_name":"thiazole metabolic process","termid":"GO:0052838"}],"gene_count":1,"genes_by_uniquename":{"SJAG_00827":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0006790"}],"interesting_parent_ids":["GO:0008150","GO:0006790"],"is_obsolete":false,"name":"thiazole biosynthetic process","references_by_uniquename":{"GO_REF:0000033":null},"synonyms":[{"name":"thiazole anabolism","type":"exact"},{"name":"thiazole biosynthesis","type":"exact"},{"name":"thiazole formation","type":"exact"},{"name":"thiazole synthesis","type":"exact"}],"termid":"GO:0052837","terms_by_termid":{"GO:0052837":null}}


id: PBO:0051062
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"immunoglobulin heavy diversity 3/OR15-3B (non-functional)","termid":"PBO:0051062"}


id: PBO:0087035
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Ribosomal 60S subunit protein L17A; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; copurifies with the Dam1 complex (aka DASH complex); homologous to mammalian ribosomal protein L17 and bacterial L22; RPL17A has a paralog, RPL17B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress","termid":"PBO:0087035"}


id: MONDO:0006095
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"A carcinoid tumor characterized by a high mitotic rate, often associated with the presence of necrosis and nuclear pleomorphism.","definition_xrefs":["NCIT:C72074"],"direct_ancestors":[{"relation_name":"is_a","term_name":"carcinoid tumor","termid":"MONDO:0005369"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"atypical carcinoid tumor","secondary_identifiers":["MEDGEN:226834","SCTID:445238008","UMLS:C1266032","EFO:1000097"],"synonyms":[{"name":"atypical carcinoid tumor","type":"exact"},{"name":"malignant carcinoid tumor","type":"exact"},{"name":"malignant carcinoid tumour","type":"exact"}],"termid":"MONDO:0006095","xrefs":{"Monarch":{"xref_id":"0006095"}}}


id: MONDO:0035401
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"anencephaly","termid":"MONDO:0000819"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0002320"}],"interesting_parent_ids":["MONDO:0002320"],"is_obsolete":false,"name":"isolated anencephaly","secondary_identifiers":["icd11.foundation:452325024","Orphanet:563609","GARD:22254","ICD10CM:Q00.0"],"termid":"MONDO:0035401","xrefs":{"Monarch":{"xref_id":"0035401"}}}


id: PBO:0028491
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-abnormal_mitotic_spindle_midzone_assembly","termid":"PBO:0028491"}


id: GO:1900453
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.","definition_xrefs":["GOC:BHF","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"negative regulation of biological process","termid":"GO:0048519"},{"relation_name":"is_a","term_name":"positive regulation of synaptic transmission","termid":"GO:0050806"},{"relation_name":"is_a","term_name":"regulation of long-term synaptic depression","termid":"GO:1900452"},{"relation_name":"negatively_regulates","term_name":"long-term synaptic depression","termid":"GO:0060292"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"positively_regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"regulates","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"negative regulation of long-term synaptic depression","synonyms":[{"name":"down regulation of LTD","type":"related"},{"name":"down regulation of long term depression","type":"broad"},{"name":"down regulation of long term synaptic depression","type":"exact"},{"name":"down-regulation of LTD","type":"related"},{"name":"down-regulation of long term depression","type":"broad"},{"name":"down-regulation of long term synaptic depression","type":"exact"},{"name":"downregulation of LTD","type":"related"},{"name":"downregulation of long term depression","type":"broad"},{"name":"downregulation of long term synaptic depression","type":"exact"},{"name":"inhibition of LTD","type":"related"},{"name":"inhibition of long term depression","type":"broad"},{"name":"inhibition of long term synaptic depression","type":"narrow"},{"name":"negative regulation of LTD","type":"related"},{"name":"negative regulation of long term depression","type":"broad"},{"name":"negative regulation of long term synaptic depression","type":"related"}],"termid":"GO:1900453"}


id: PBO:0017816
data:
  {"annotation_feature_type":"gene","cv_name":"disease_associated","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Familial Kufor-Rakeb Syndrome","termid":"PBO:0017816"}


id: GO:0018950
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.","definition_xrefs":["GOC:jl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"xylene metabolic process","termid":"GO:0018948"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"o-xylene metabolic process","secondary_identifiers":["UM-BBD_pathwayID:oxy"],"synonyms":[{"name":"o-xylene metabolism","type":"exact"},{"name":"ortho-xylene metabolic process","type":"exact"},{"name":"ortho-xylene metabolism","type":"exact"}],"termid":"GO:0018950"}


id: PR:Q8WZJ9
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A solute carrier family 35 member B1 that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["OMA:SCHPO02527","PRO:DNx","PANTHER:PTHR10778:SF10"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"UDP-galactose transporter homolog 1 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC839.11c","secondary_identifiers":["UniProtKB:Q8WZJ9"],"synonyms":[{"name":"Spom972h-SLC35B1","type":"exact"}],"termid":"PR:Q8WZJ9"}


id: MONDO:0007068
data:
  {"annotated_genes":["SJAG_02850"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[87298],"is_not":false,"summary":null,"term":"MONDO:0007068"}]},"cv_name":"mondo","definition":"Adenylosuccinate lyase deficiency (ADSL deficiency) is a disorder of purine metabolism characterized by intellectual disability, psychomotor delay and/or regression, seizures, and autistic features.","definition_xrefs":["Orphanet:46"],"direct_ancestors":[{"relation_name":"is_a","term_name":"inborn disorder of amino acid metabolism","termid":"MONDO:0004736"},{"relation_name":"is_a","term_name":"inborn disorder of purine metabolism","termid":"MONDO:0019236"}],"gene_count":1,"genes_by_uniquename":{"SJAG_02850":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0005066"},{"rel_name":"is_a","termid":"MONDO:0004736"},{"rel_name":"is_a","termid":"MONDO:0019254"}],"interesting_parent_ids":["MONDO:0005066","MONDO:0019254","MONDO:0004736"],"is_obsolete":false,"name":"adenylosuccinate lyase deficiency","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["UMLS:C0268126","OMIM:103050","MEDGEN:78641","ICD9:277.2","SCTID:15285008","DOID:0050762","GARD:550","MESH:C538235","icd11.foundation:1725611919"],"synonyms":[{"name":"ADSL deficiency","type":"exact"},{"name":"ADSLD","type":"related"},{"name":"Adsl deficiency","type":"related"},{"name":"adenylosuccinase deficiency","type":"exact"},{"name":"adenylosuccinase lyase deficiency","type":"related"},{"name":"adenylosuccinate lyase deficiency","type":"exact"},{"name":"inborn (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity disorder","type":"exact"},{"name":"inborn error of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity","type":"exact"},{"name":"rare inborn error of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity","type":"exact"}],"termid":"MONDO:0007068","terms_by_termid":{"MONDO:0007068":null},"xrefs":{"Monarch":{"xref_id":"0007068"}}}


id: FYPO:0003521
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype in which the amount of L-ergothioneine measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell","termid":"FYPO:0000991"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0001985"],"is_obsolete":false,"name":"decreased cellular L-ergothioneine level","synonyms":[{"name":"decreased L-ergothioneine level","type":"exact"},{"name":"decreased cellular L-ergothioneine accumulation","type":"related"},{"name":"reduced cellular L-ergothioneine level","type":"exact"}],"termid":"FYPO:0003521"}


id: PBO:0055945
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"leucine rich repeat containing 53","termid":"PBO:0055945"}


id: MONDO:0003320
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Wilms tumor of the kidney characterized by the predominance of the blastema component.","definition_xrefs":["NCIT:C9147"],"direct_ancestors":[{"relation_name":"is_a","term_name":"kidney Wilms tumor","termid":"MONDO:0019004"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"MONDO:0004992"},{"rel_name":"is_a","termid":"MONDO:0005240"}],"interesting_parent_ids":["MONDO:0004992","MONDO:0005240"],"is_obsolete":false,"name":"blastema predominant kidney Wilms tumor","secondary_identifiers":["MEDGEN:83528","DOID:5182","UMLS:C0279609"],"synonyms":[{"name":"blastema predominant Wilms tumor","type":"exact"},{"name":"blastema predominant Wilms tumour","type":"exact"},{"name":"blastema predominant kidney Wilms tumor","type":"exact"},{"name":"blastema predominant kidney Wilms' tumor","type":"related"},{"name":"blastema predominant kidney Wilms' tumour","type":"related"},{"name":"blastema predominant kidney adenosarcoma","type":"exact"},{"name":"blastema predominant nephroblastoma","type":"exact"},{"name":"blastema predominant renal Wilm's tumor","type":"exact"},{"name":"blastema predominant renal Wilm's tumour","type":"exact"},{"name":"blastema predominant renal Wilms tumor","type":"exact"},{"name":"blastema predominant renal Wilms tumour","type":"exact"},{"name":"blastema predominant renal Wilms' tumor","type":"exact"},{"name":"blastema predominant renal Wilms' tumour","type":"exact"},{"name":"blastema predominant renal adenosarcoma","type":"exact"}],"termid":"MONDO:0003320","xrefs":{"Monarch":{"xref_id":"0003320"}}}


id: GO:0080134
data:
  {"annotated_genes":["SJAG_02244","SJAG_01205","SJAG_03705","SJAG_01528","SJAG_03345","SJAG_05000","SJAG_00573","SJAG_01253","SJAG_03048","SJAG_00293","SJAG_03568","SJAG_02392","SJAG_03160","SJAG_04666","SJAG_01632","SJAG_04457","SJAG_02104","SJAG_03969","SJAG_00424","SJAG_03695","SJAG_03263","SJAG_01114","SJAG_00610","SJAG_03417","SJAG_00642","SJAG_02331","SJAG_00823","SJAG_02682","SJAG_01150","SJAG_00369","SJAG_01585","SJAG_04522","SJAG_02292","SJAG_01787","SJAG_04825","SJAG_02058"],"annotation_feature_type":"gene","cv_annotations":{"biological_process":[{"annotations":[120364,101367,105750,97763,109017,109585],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903138"},{"annotations":[104312],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001033"},{"annotations":[79320,79843],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904293"},{"annotations":[113761],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904332"},{"annotations":[113714,93128,107864],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000639"},{"annotations":[69403,89950,92650,94310,119938,91316],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903139"},{"annotations":[71107,68112],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1903833"},{"annotations":[118413,91141],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1900039"},{"annotations":[114041,119306],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0045739"},{"annotations":[95779,112175],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000781"},{"annotations":[112924],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1905168"},{"annotations":[109382],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2001034"},{"annotations":[115450,62232,80213,115449],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000640"},{"annotations":[104335],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:1904547"},{"annotations":[74391,92794],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:2000779"},{"annotations":[111308],"is_not":false,"rel_names":["is_a"],"summary":null,"term":"GO:0010569"}]},"cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).","definition_xrefs":["GOC:dhl"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of response to stimulus","termid":"GO:0048583"},{"relation_name":"regulates","term_name":"response to stress","termid":"GO:0006950"}],"gene_count":36,"genes_by_uniquename":{"SJAG_00293":null,"SJAG_00369":null,"SJAG_00424":null,"SJAG_00573":null,"SJAG_00610":null,"SJAG_00642":null,"SJAG_00823":null,"SJAG_01114":null,"SJAG_01150":null,"SJAG_01205":null,"SJAG_01253":null,"SJAG_01528":null,"SJAG_01585":null,"SJAG_01632":null,"SJAG_01787":null,"SJAG_02058":null,"SJAG_02104":null,"SJAG_02244":null,"SJAG_02292":null,"SJAG_02331":null,"SJAG_02392":null,"SJAG_02682":null,"SJAG_03048":null,"SJAG_03160":null,"SJAG_03263":null,"SJAG_03345":null,"SJAG_03417":null,"SJAG_03568":null,"SJAG_03695":null,"SJAG_03705":null,"SJAG_03969":null,"SJAG_04457":null,"SJAG_04522":null,"SJAG_04666":null,"SJAG_04825":null,"SJAG_05000":null},"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of response to stress","references_by_uniquename":{"GO_REF:0000033":null,"GO_REF:0000107":null,"GO_REF:0000117":null},"termid":"GO:0080134","terms_by_termid":{"GO:0010569":null,"GO:0045739":null,"GO:1900039":null,"GO:1903138":null,"GO:1903139":null,"GO:1903833":null,"GO:1904293":null,"GO:1904332":null,"GO:1904547":null,"GO:1905168":null,"GO:2000639":null,"GO:2000640":null,"GO:2000779":null,"GO:2000781":null,"GO:2001033":null,"GO:2001034":null}}


id: PBO:0091629
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"phenazine biosynthesis PhzF protein family","termid":"PBO:0091629"}


id: PBO:0079858
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"unc-93 homolog B7 (pseudogene)","termid":"PBO:0079858"}


id: PBO:0088213
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"transposable element zinc finger related protein","termid":"PBO:0088213"}


id: PBO:0050831
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"hypoxia up-regulated 1","termid":"PBO:0050831"}


id: PBO:0073724
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SLAM family member 6","termid":"PBO:0073724"}


id: PR:O94309
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"A protein that is a translation product of the Schizosaccharomyces pombe 972h- git11 gene.","definition_xrefs":["PRO:DNx","UniProtKB:O94309"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"guanine nucleotide-binding protein subunit gamma (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC215.04","synonyms":[{"name":"Spom972h-git11","type":"exact"}],"termid":"PR:O94309"}


id: PBO:0090387
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"pig-Z, alpha-1,2-mannosyltransferase Smp3","termid":"PBO:0090387"}


id: PBO:0075548
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"SPECC1 pseudogene 2","termid":"PBO:0075548"}


id: PBO:0083430
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YER076C","termid":"PBO:0083430"}


id: GO:0098828
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"is_a","term_name":"regulation of nervous system process","termid":"GO:0031644"},{"relation_name":"is_a","term_name":"regulation of membrane potential","termid":"GO:0042391"},{"relation_name":"regulates","term_name":"inhibitory postsynaptic potential","termid":"GO:0060080"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0023052","GO:0008150"],"is_obsolete":false,"name":"modulation of inhibitory postsynaptic potential","synonyms":[{"name":"regulation of inhibitory postsynaptic potential","type":"exact"}],"termid":"GO:0098828"}


id: PR:Q9P7L5
data:
  {"annotation_feature_type":"gene","cv_name":"protein","definition":"An ornithine aminotransferase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-.","definition_xrefs":["PRO:DNx","OMA:SCHPO03865"],"direct_ancestors":[{"relation_name":"is_a","term_name":"Schizosaccharomyces pombe 972h- protein","termid":"PR:000029043"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ornithine aminotransferase car2 (Schizosaccharomyces pombe 972h-)","pombase_gene_id":"SPBC21C3.08c","secondary_identifiers":["UniProtKB:Q9P7L5"],"synonyms":[{"name":"Spom972h-OAT","type":"exact"},{"name":"ornithine--oxo-acid aminotransferase (Schizosaccharomyces pombe 972h-)","type":"exact"}],"termid":"PR:Q9P7L5"}


id: PBO:0075441
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"secreted protein acidic and cysteine rich","termid":"PBO:0075441"}


id: PBO:0089050
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"2',3'-cyclic-nucleotide 3'-phosphodiesterase","termid":"PBO:0089050"}


id: PBO:0005231
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"DUF1941 family protein","termid":"PBO:0005231"}


id: PBO:0005745
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"ammonium transporter Amt1","termid":"PBO:0005745"}


id: PBO:0013814
data:
  {"annotation_feature_type":"gene","cv_name":"warning","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"was previously annotated as atg14","termid":"PBO:0013814"}


id: GO:0071539
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"A process in which a protein is transported to, or maintained at, the centrosome.","definition_xrefs":["GOC:ecd"],"direct_ancestors":[{"relation_name":"is_a","term_name":"protein localization to microtubule organizing center","termid":"GO:1905508"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0051179"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0051179"],"is_obsolete":false,"name":"protein localization to centrosome","synonyms":[{"name":"protein localisation to centrosome","type":"exact"}],"termid":"GO:0071539"}


id: MONDO:1011140
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","definition":"Choanal atresia that occurs in domestic cat.","definition_xrefs":["MONDO:patterns/nonhuman_disease"],"direct_ancestors":[{"relation_name":"is_a","term_name":"choanal atresia, non-human animal","termid":"MONDO:1010289"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"choanal atresia, domestic cat","secondary_identifiers":["OMIA:001764-9685"],"termid":"MONDO:1011140","xrefs":{"Monarch":{"xref_id":"1011140"}}}


id: GO:0045168
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.","definition_xrefs":["GOC:go_curators","GOC:tb","GOC:dph"],"direct_ancestors":[{"relation_name":"is_a","term_name":"cell-cell signaling","termid":"GO:0007267"},{"relation_name":"part_of","term_name":"cell fate commitment","termid":"GO:0045165"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"},{"rel_name":"is_a","termid":"GO:0023052"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"cell-cell signaling involved in cell fate commitment","synonyms":[{"name":"cell fate commitment, cell-cell signaling","type":"exact"},{"name":"cell fate commitment, cell-cell signalling","type":"exact"},{"name":"cell-cell signaling during in cell fate commitment","type":"exact"},{"name":"cell-cell signaling resulting in cell fate commitment","type":"exact"},{"name":"cell-cell signalling during cell fate commitment","type":"exact"},{"name":"cell-cell signalling involved in cell fate specification","type":"narrow"},{"name":"cell-cell signalling resulting in cell fate commitment","type":"exact"}],"termid":"GO:0045168"}


id: PBO:0053366
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 278","termid":"PBO:0053366"}


id: PBO:0079198
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"TSPY like 1","termid":"PBO:0079198"}


id: GO:0075064
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.","definition_xrefs":["GOC:pamgo_curators"],"gene_count":0,"genotype_count":0,"name":"obsolete negative regulation invasive hypha growth (obsolete GO:0075064)","synonyms":[{"name":"negative regulation of symbiont invasive hypha formation in host","type":"exact"},{"name":"negative regulation of symbiont invasive hypha formation within host","type":"exact"}],"termid":"GO:0075064"}


id: GO:0086009
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.","definition_xrefs":["GOC:BHF","GOC:mtg_cardiac_conduct_nov11"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of membrane potential","termid":"GO:0042391"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"membrane repolarization","termid":"GO:0086009"}


id: PBO:0058516
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5704","termid":"PBO:0058516"}


id: PBO:0027497
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-sensitive_to_FR901464","termid":"PBO:0027497"}


id: MONDO:0016582
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"congenital heart malformation","termid":"MONDO:0019512"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"congenital mitral malformation","secondary_identifiers":["GARD:1495","Orphanet:2447","UMLS:C5680882","MEDGEN:1842184"],"termid":"MONDO:0016582","xrefs":{"Monarch":{"xref_id":"0016582"}}}


id: FYPO:0006705
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more pentose phosphates measured in a cell is lower than normal.","definition_xrefs":["PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"decreased level of substance in cell during vegetative growth","termid":"FYPO:0001329"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0001985"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0000002"}],"interesting_parent_ids":["FYPO:0001985","FYPO:0001320","FYPO:0000002"],"is_obsolete":false,"name":"decreased cellular pentose phosphate level","synonyms":[{"name":"decreased cellular pentose phosphate level during mitotic cell cycle","type":"related"},{"name":"decreased cellular pentose phosphate level during vegetative growth","type":"exact"},{"name":"decreased cellular pentose-phosphate level","type":"exact"},{"name":"decreased pentose phosphate accumulation","type":"related"},{"name":"reduced cellular pentose phosphate level","type":"exact"}],"termid":"FYPO:0006705"}


id: PBO:0043950
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"crystallin beta B2","termid":"PBO:0043950"}


id: GO:0090536
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters.","definition_xrefs":["GOC:krc"],"direct_ancestors":[{"relation_name":"is_a","term_name":"ISWI-type complex","termid":"GO:0031010"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0005575"},{"rel_name":"part_of","termid":"GO:0005634"},{"rel_name":"part_of","termid":"GO:0005694"},{"rel_name":"is_a","termid":"GO:0032991"}],"interesting_parent_ids":["GO:0005575","GO:0005634","GO:0005694","GO:0032991"],"is_obsolete":false,"name":"NoRC complex","termid":"GO:0090536"}


id: PBO:0018153
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Clr6 histone deacetylase complex subunit Nts1","termid":"PBO:0018153"}


id: GO:0003157
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.","definition_xrefs":["GOC:mtg_heart"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"heart development","termid":"GO:0007507"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"endocardium development","termid":"GO:0003157"}


id: PBO:0030310
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-decreased_protein_level_in_germinating_spore","termid":"PBO:0030310"}


id: PBO:0058448
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 5087","termid":"PBO:0058448"}


id: SO:0000029
data:
  {"annotation_feature_type":"gene","cv_name":"sequence","definition":"The canonical base pair, where two bases interact via WC edges, with glycosidic bonds oriented cis relative to the axis of orientation.","definition_xrefs":["PMID:12177293"],"direct_ancestors":[{"relation_name":"is_a","term_name":"base_pair","termid":"SO:0000028"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"WC_base_pair","synonyms":[{"name":"WC base pair","type":"exact"},{"name":"Watson Crick base pair","type":"exact"},{"name":"Watson-Crick base pair","type":"related"},{"name":"Watson-Crick pair","type":"exact"},{"name":"canonical base pair","type":"exact"}],"termid":"SO:0000029"}


id: GO:1901187
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway.","definition_xrefs":["GOC:BHF","GOC:TermGenie"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of signal transduction","termid":"GO:0009966"},{"relation_name":"regulates","term_name":"ephrin receptor signaling pathway","termid":"GO:0048013"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"regulates","termid":"GO:0023052"},{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150","GO:0023052"],"is_obsolete":false,"name":"regulation of ephrin receptor signaling pathway","synonyms":[{"name":"regulation of Eph receptor signaling pathway","type":"exact"},{"name":"regulation of Eph receptor signalling pathway","type":"exact"}],"termid":"GO:1901187"}


id: PBO:0084849
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"Mitochondrial ribosomal protein of the large subunit; involved together with Mrp7p in assembly of cytochrome c oxidase","termid":"PBO:0084849"}


id: GO:0099072
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane.","definition_xrefs":["GOC:dos"],"direct_ancestors":[{"relation_name":"is_a","term_name":"regulation of biological quality","termid":"GO:0065008"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"regulation of postsynaptic membrane neurotransmitter receptor levels","termid":"GO:0099072"}


id: GO:0035174
data:
  {"annotation_feature_type":"gene","cv_name":"molecular_function","definition":"OBSOLETE. Catalysis of the transfer of a phosphate group to a serine residue of a histone.","definition_xrefs":["GOC:bf"],"gene_count":0,"genotype_count":0,"name":"obsolete histone serine kinase activity (obsolete GO:0035174)","synonyms":[{"name":"histone-serine kinase activity","type":"exact"}],"termid":"GO:0035174"}


id: FYPO:0003623
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"OBSOLETE. A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of threonine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to heat.","definition_xrefs":["PomBase:mah"],"gene_count":0,"genotype_count":0,"name":"obsolete normal protein threonine phosphorylation during cellular response to heat (obsolete FYPO:0003623)","synonyms":[{"name":"normal protein threonine phosphorylation during cellular response to heat during mitotic cell cycle","type":"related"},{"name":"normal protein threonine phosphorylation during cellular response to heat during vegetative growth","type":"exact"}],"termid":"FYPO:0003623"}


id: MONDO:0016851
data:
  {"annotation_feature_type":"gene","cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"chromosome X disorder","termid":"MONDO:0700027"},{"relation_name":"is_a","term_name":"uniparental disomy","termid":"MONDO:0700086"}],"gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"maternal uniparental disomy of chromosome X","secondary_identifiers":["MEDGEN:1673747","UMLS:C5191056","Orphanet:261519","GARD:20783","icd11.foundation:573923144"],"synonyms":[{"name":"UPD(X)mat","type":"exact"},{"name":"maternal uniparental disomy of chromosome type X","type":"exact"}],"termid":"MONDO:0016851","xrefs":{"Monarch":{"xref_id":"0016851"}}}


id: GO:0030917
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.","definition_xrefs":["GOC:dgh"],"direct_ancestors":[{"relation_name":"is_a","term_name":"anatomical structure development","termid":"GO:0048856"},{"relation_name":"part_of","term_name":"brain development","termid":"GO:0007420"},{"relation_name":"part_of","term_name":"rostrocaudal neural tube patterning","termid":"GO:0021903"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"midbrain-hindbrain boundary development","synonyms":[{"name":"MHB development","type":"exact"},{"name":"isthmic organizer development","type":"exact"},{"name":"isthmomesencephalic boundary development","type":"exact"},{"name":"isthmus development","type":"exact"},{"name":"midbrain-hindbrain orgainizer development","type":"exact"}],"termid":"GO:0030917"}


id: GO:0070118
data:
  {"annotation_feature_type":"gene","cv_name":"cellular_component","definition":"The lipid bilayer membrane of any thylakoid within an organellar chromatophore.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"thylakoid membrane","termid":"GO:0042651"},{"relation_name":"is_a","term_name":"organellar chromatophore membrane","termid":"GO:0070112"},{"relation_name":"part_of","term_name":"organellar chromatophore thylakoid","termid":"GO:0070116"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"part_of","termid":"GO:0031410"},{"rel_name":"part_of","termid":"GO:0005737"},{"rel_name":"is_a","termid":"GO:0005575"}],"interesting_parent_ids":["GO:0031410","GO:0005575","GO:0005737"],"is_obsolete":false,"name":"organellar chromatophore thylakoid membrane","synonyms":[{"name":"Paulinella-type chromatophore thylakoid membrane","type":"exact"}],"termid":"GO:0070118"}


id: PBO:0067349
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"RNA, 7SL, cytoplasmic 446, pseudogene","termid":"PBO:0067349"}


id: PBO:0054303
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"long intergenic non-protein coding RNA 1695","termid":"PBO:0054303"}


id: PBO:0057965
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"microRNA 3686","termid":"PBO:0057965"}


id: GO:0032327
data:
  {"annotation_feature_type":"gene","cv_name":"biological_process","definition":"The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.","definition_xrefs":["GOC:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"molybdopterin cofactor catabolic process","termid":"GO:0032325"},{"relation_name":"is_a","term_name":"W-molybdopterin cofactor metabolic process","termid":"GO:0042046"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"GO:0008150"}],"interesting_parent_ids":["GO:0008150"],"is_obsolete":false,"name":"W-molybdopterin cofactor catabolic process","synonyms":[{"name":"Moco catabolic process","type":"broad"},{"name":"Moco catabolism","type":"broad"},{"name":"W-molybdopterin cofactor breakdown","type":"exact"},{"name":"W-molybdopterin cofactor catabolism","type":"exact"},{"name":"W-molybdopterin cofactor degradation","type":"exact"}],"termid":"GO:0032327"}


id: MONDO:0013258
data:
  {"annotated_genes":["SJAG_04616"],"annotation_feature_type":"gene","cv_annotations":{"mondo":[{"annotations":[89183],"is_not":false,"summary":null,"term":"MONDO:0013258"}]},"cv_name":"mondo","direct_ancestors":[{"relation_name":"is_a","term_name":"autism, susceptiblity to","termid":"MONDO:0020836"}],"gene_count":1,"genes_by_uniquename":{"SJAG_04616":null},"genotype_count":0,"is_obsolete":false,"name":"autism, susceptibility to, 16","references_by_uniquename":{"PB_REF:0000006":null},"secondary_identifiers":["MEDGEN:462027","UMLS:C3150677","OMIM:613410"],"synonyms":[{"name":"AUTS16","type":"related"},{"name":"autism susceptibility 16","type":"exact"},{"name":"autism with or without seizures","type":"related"},{"name":"autism, susceptibility to, 16","type":"exact"},{"name":"autism, susceptibility to, type 16","type":"exact"},{"name":"susceptibility to autism 16","type":"related"}],"termid":"MONDO:0013258","terms_by_termid":{"MONDO:0013258":null},"xrefs":{"Monarch":{"xref_id":"0013258"}}}


id: PBO:0042579
data:
  {"annotation_feature_type":"gene","cv_name":"PomBase gene products","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"cyclin dependent kinase inhibitor 3","termid":"PBO:0042579"}


id: PBO:0026640
data:
  {"annotation_feature_type":"gene","cv_name":"cvterm_property_type","gene_count":0,"genotype_count":0,"is_obsolete":false,"name":"annotation_extension_relation-elongated_vegetative_cell_during_cellular_response_to_UV","termid":"PBO:0026640"}


id: FYPO:0005695
data:
  {"annotation_feature_type":"genotype","cv_name":"fission_yeast_phenotype","definition":"A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of astral microtubules from the spindle pole body does not occur during mitosis.","definition_xrefs":["PMID:19001497","PomBase:mah"],"direct_ancestors":[{"relation_name":"is_a","term_name":"abnormal cell cycle process","termid":"FYPO:0002734"},{"relation_name":"is_a","term_name":"abolished cellular process","termid":"FYPO:0005449"},{"relation_name":"is_a","term_name":"abolished cytoplasmic microtubule nucleation","termid":"FYPO:0005693"}],"gene_count":0,"genotype_count":0,"interesting_parent_details":[{"rel_name":"is_a","termid":"FYPO:0005447"},{"rel_name":"is_a","termid":"FYPO:0000002"},{"rel_name":"is_a","termid":"FYPO:0000054"},{"rel_name":"is_a","termid":"FYPO:0000631"},{"rel_name":"is_a","termid":"FYPO:0001320"},{"rel_name":"is_a","termid":"FYPO:0001985"}],"interesting_parent_ids":["FYPO:0000002","FYPO:0000631","FYPO:0000054","FYPO:0001985","FYPO:0005447","FYPO:0001320"],"is_obsolete":false,"name":"abolished astral microtubule nucleation during mitosis","synonyms":[{"name":"abolished astral microtubule nucleation during mitosis during vegetative growth","type":"exact"},{"name":"abolished astral microtubule nucleation during mitotic nuclear division","type":"exact"},{"name":"astral microtubule nucleation during mitosis abolished","type":"exact"}],"termid":"FYPO:0005695"}


